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MEDICAL NEWS #. §§ wº : .. * * Y. ** * { º tion to 'Skada—Cholera—the Berlin Battle—English Animal * § # 3 #. º: ~}. * * S ** 3. 2 º' —É -ºf ºn Eclipse— * ; :# 3 *% ; -- ºr - ºngº Eclipse—The Title of Doctor..................8-9 à $. c sº -—-* . #. 3r : º º , sº : . CIFNiCA}, MIEMORANDA tº ** §, 3rºnic Injections of Morphia—Hernia Puncture—Morphia ... . . . fº. # t *:: * iº- #. ºsºbiealſy in Erysipelas 9–12 *.*, * & S * * º ~ *.*.*, , § ** *g *: * figãºs. •ºr º * * , ** - Y. & 3. | - * º ºg sº tº ------12 ...tro.ºadsrs of the clinic.... & . . ; as "º", *: * | 2 5 * > * **. $3, $s.” .* Y; i 4. -: ***** .* *::: s:: * , rººmmit Kees. -- #2 •º. &º.º. º *; -* *. & & 3. * * * < ... a-, erº, sº *—— *: &; t 3. : z-z-z- , * *. sº º **** * { - * *--- # . *----- Isº * Now is the time to subscribe for THE CLINrc. With , sº 4. •ºr the presenat number begins a new volume. As difficul- == s-º-º-º- . . . E ties have been experienced in securing tack numbers ### & - * we advise thºs wº intend to subscribe to do so at once. * * *** g &- **** iºt & Every physician ought to take the CLIN1c, becauseTap ment. The time for surgical interference, if indeed CITNIC is, in sh # tº º treatment by the knife is ever justifiable in such cases is, in short, an exponent of modern medicine. *as long passed; we may, however, derive some useful & Y *; *. *- 2 - - [JAN. 6, 1872. T IHI IE C T , T IN I. C. sº lessons in the management of hernia. He is 64 years of age. The tumor which you see extending from the pubes to knees is a double scrotal hernia—reducible on the right, irreducible on the left side. The left hernia is of 27 years standing, and occurred while he was engaged at some hard labor in a tan yard. The rup- ture on the right side happºned 5 years later. The great mass of this tumor is made by the protrusion on the left side, and this is irreducible; the right hernia, the reducible is not larger than the patient's fist. The penis, by the weight of the tumor dragging the skin from above downwards is entirely obscured. When he wishes to urinate he reduces the right hernia, this, pushing the skin upwards exposes the penis. The size of the scrotum is immense—measuring 13 inches in length and 27 inches in circumference. Dr. Gross re- ports a case 12 inches in length and nearly 2 feet in cir- cumference. Strange as it may seem this man, with this fearful encumbrance, makes a living by peddling. He suffers as do all persons with large irreducible herniae from disorders of digestion, colicky pains and constipa- tion of bowels. He finds most comfort in a fluid diet. Why is this hermia irreducible 7 First, from adhesions between the sac and its contents; second, from hyper- trophy of the protruded viscera, this is peculiarly true of the omentum ; third, from a contracted condition of the peritoneal cavity. * Could this have been prevented ? The answer to this question suggests some points of vital interest to us in the treatment of hernia in its early days. A scrotal hernia which is at first reducible may at låst become irreducible by neglect, by allowing it to remain without the abdomen. The ring contracts without strangulating, the protruded parts become inflamed, plastic matter unites them to each other, and to the sac. The lesson which I would impress upon you and which you should impress on your patients is immediate and permanent reduction and the early application of the truss in these cases, by the judicious use of these measures you may cure your patient, but if do not, you will most assuredly save him from the fearful calamity which has befallen this poor man. * What can you do for a case of irreducible hernia before it has attained great size? It is said that some cases, even old ones have been cured by long confinement to bed, low diet and free purgation; but you will find few persons who will submit to this course, especially when you cannot give them positive assurance of relief. Is the knife justifiable 2 Under some cir- cumstances I think it is. The following case will illustrate my meaning. In 1864 David Turner aged 15, entered the Commercial Hospital with an irreducible scrotal hernia, complicated with hydro- cele. The hernia was congenital, but had been irreducible but for two months. The scrotum was about six inches in length and three inches in diameter, and was daily increasing. He was an intelligent lad and was willing to take the hazard of an operation hº- rather than the encumbrance of what promised to be; * * and that very soon, an immense serotal tumor. I opened the sac found the hernia omental, returned it after breaking up the adhesions, and in one month he left the hospital entirely well. & Stricture—Prostatic Stricture. I present to you at this meeting two cases of stricture of the urethra. They are both permanent strictures, you all know well the classification of strictures, the spas- modic and the permanent; the former is insignificant— as simple as an ordinary cramp or muscular spasm, and hardly deserves to be placed along with the latter which is an impairment most painful to the patient and most difficult to the surgeon. Indeed I know of no non-malig- nant disease of more grave import than permanent stricture. What is stricture ? I think the definition of Sir Charles Bellis a good and correct one, he looked upon the urethra as a closed canal the sides of which fall together except when called into use. Now in stricture, this canal as he says has “lost its power of dilating.” Of these permanent obstructions I propose to speak to-day. What form do these obstructions assume? First you have linear stricture, seldom seen, it is a mere membra- nous screen stretched across the channel—thin, filmy, easily broken down; the first introduction of a sound usually dissipates it. Occasionally it takes the crescen- tic shape and encroaches upon but one side of the canal. Second, what is called the “bridle stricture” some- times presents itself. This kind of stricture seems to me to be more often in the imagination of the surgeon than in reality. It is described in your books as consisting of a number of bands thrown across the urethra, and most authorities as if to relieve themselves, suggest that these bands are but the result of “false passages” made by the injudiscious use of the sound. For myself, I cannot say that I have found them either as the result of disease or as following a violent and reckless use of instruments. Third, annular strictnre, this variety of urethral ob- struction is a limited, a closely defined stricture, as if a cord was thrown around the canal, contracting it and diminishing its dilating ability. This obstruction is rare, and when found is easily managed. Fourth, the tortuous stricture. This is the leading, the most difficult to manage and, unfortunately, the most frequent form of obstruction of the urethra. The plastic matter thrown out beneath the mucus mem- brane (never upon it except in those questionable in- stances of diphtheretic deposite) abridges the canal—first here, then there, until the calliber and dilating capacity of the tube is so encroached upon that “dilata- tion” complete, satisfactory to the patient, is lost, and the precess of micturition is accompanied with straining and pain, the intensity of the pain and the violence of *. JAN. 6, 1872.] the straining depending on the extent and unyielding quality of the stricture. In what part of the urethra are strictures most fre- quently found? Sir Henry Thompson after examining a large number of cases and specimens comes to the con- clusion that the contraction is most commonly found in the posterior part of the spongy portion of the urethra. Liston, depending on measurement instead of the more reliable guide, i. e., the anatomical relations of the canal, contended that the most frequent seat of stricture was about four inches from the meatus. The membra- nous portion of the urethra—that between the bulb and the apex of the prostate has been according to the ex- perience of some most frequently affected. Sometimes the whole canal is contracted—such an instance I will show you to-day. Is the prostatic portion of the urethra ever affected by stricture? Sir Henry Thompson says that no specimen of prostatic stricture is to be found in the museums of Paris, London or Edinburg; hence he ques- tions its existence. Leroy D'Etiolles, however, affirms its occurrence and refers to a specimen of it in his own collection. Ricord believed also in stricture of the pros- tatic urethra. Sir Henry in his learned work on stric- tures says, “at present, therefore, the existence of pros- tatic stricture appears to rest on the observations of Leroy D'Etiolles and Ricord. Its excessive rarity to say the least is at all events demonstrated.” I certainly have seen two cases of prostatic stricture during the past summer, and one of them I will present to you, to-day. The first was a patient from a neighboring state. An examination showed a stricture occupying about one inch and a half of the posterior portion of the Spongyurethra. The contraction was so great that a No. 2 bougie was introduced with difficulty. The dila- tation of this stricture developed the fact that the membranous portion was largely expanded, and the prostatic portion contracted. After long and repeated efforts the prostatic stricture yielded. The patient now before you consulted me last May for a stricture in the posterior part of the Spongy por- tion. I succeeded in dilating it until a No. 10 bougie could be introduced with ease. He passed a fair stream of water for some time, but gradually the stream began to diminish in size, and micturition was attended with pain and straining. He returned to the city and on examination I found the obstruction in the prostatic Portion. A No. 10 could still be introduced with ease to the apex of the prostrate, but was there arrested. With No. 3 I could enter but could not pass through the prostatic urethra. In attempting to withdraw the instrument it was held with great firmness by the stric- ture. I could not have been mistaken in the seat of the contraction for with my finger in the recºurm i could feel the instrument in the canal surrounded by the gland. After daily trials for a week I succeeded for the first time this morning in passing the instrument through the stricture into the bladder. By gradual dilatation I expect te cure the stricture here involving the pros- TIEI IET: C T , IIINTIC . - 3 tatic just as I did that situated in the spongy portion. The next patient, Martin, whom I present you has had stricture for ten years, and has two urinary fistulae. He voids his water in great suffering, most of it finding its way through the fistulae, but little passes by the urethra. The meatus is contracted and I find it impos- sible to introduce a No. 3 bougie. I now try No. 2 and succeed in introducing it about two inches. No. 1 pass- es as you see along the canal until I reach almost the termination of the spongy portion of the urethra, at this point this small instrument meets with obstruction, it may be caught in a fold of the mucous membrane, I withdraw it, and again, as I advance it, the obstruction appears at the same point. I use as you observe the slightest force in advancing the instrument. I cannot impress too strongly upon you the importance of great gentleness and delicacy in introducing an instrument into the urethra under all circumstances and especially when you have its capacity abridged and are using a small bougie. But little force is required to thrust such an instrument through the mucous membrane; the bad results of such an accident are easily foretold. The gravity of this case is apparent to you, the stricture involves the whole of the urethra to the bulb and may extend even beyond it. - Whāt are the effects of stricture? You generally find the canal behind the stricture dilated. The bladder is usually contracted and its walls, the muscular portion, thickened. A case is reported in which the vesical walls looked as thick and strong as the walls of the left ven- tricle of the heart. Sometimes these vesical muscles under great straining give way at one or more points, sacs and pockets form, the rupture of these cause urinary infiltration and this is followed by consequences the most disastrous. The kidneys and ureters suffer; in old cases you are likely to have degeneration of the former and dilatation of the latter. When a breach occurs in the urethra behind the stricture, perineal abscesses form and leave behind them perineal, urinary fistulae. This has been the case in the patient before you. The rup- ture of the urethra under constant straining allowed the urine to pass into the cellular tissue, abscesses formed and these, when opened, left adventitious urinal tracts. If you could see the violent exertions of this poor man when he is passing his water you would understand why in such cases the whole detrusor urinae apparatus is en- larged and strengthened for the purpose of forcing the urine through the lessened canal. - What is the treatment of stricture? Three methods are resorted to, viz: gradual dilatation, forcible rup- ture and urethrotomy. It is said that any stricture which allows the escape | of urine however small the quantity can be passed with a bougie and that dilatation under such circumstances complete and perfect, is practicable. This proposition is generally, but not always true. You may have a stricture that is so hard, so unyielding that it cannot be overcome by gradual dilatation. Again, you may have 4 TIEEE THE C T , T N T C . [JAN. 6, 1872. a stricture which yields temporarily to the introduction of sounds until a large size is admitted, and yet in twenty-four or forty-eight hours of rest, the whole ad- vantage gained is lost. Prof. Syme has reported such cases. Under these circumstances you must either re- sort to rupture or internal or external urethrotomy. For rupture or forcible dilatation of stricture a variety of instruments have been invented. The instrument of Mr. Holt, which I show you has been received with much favor and the best results have followed its use. It consists of two plates joined together, having the shape of a catheter. When the instrument has passed the constricted point a staff is inserted between the plates and forced down to and through the stricture. The dilator which I now hold in my hand is of French man- ufacture and is still more simple. There is a staff about the size of a No. 3 bougie—this is introduced and upon it slides an olive shaped body, this latter, wedge-like in action, is forced through the stricture. Still more nu- merous are the instruments invented for internal urethrotomy. The best which I have seen is Maison- neuve's, it is simple in construction and easy of manage- ment. A No. 2 steel bougie is grooved on its concavity, into this grove a staff is fitted carrying a blade with its cutting edge in front. It is arranged so that the incision may be from below upwards or from side to side, Experience shows that there are certain forms of stricture which cannot be overcome by gradual dilata- tion, and it is in these intractable cases that rupture or incisions are resorted to. Each surgeon has and is wedded to a favorite plan. One always resorts to rup- ture, another sees no virtue in breaking up a stricture in this way and always resorts to internal urethrotomy, whilst Syme, after doing most to enforce the axiom that all strictures are permeable and all permeable strictures can be dilated, arrived at the conclusion later in life that there were certain forms of urethral obstruction that could only be treated successfully by perineal sec- tion or external urethrotomy. He gives two classes of these cases. 1st. Cases in which the urethra is so irrit- able that the introduction of an instrument instead of alleviating, aggravates the suffering. 2d. Cases in which dilatation is rendered useless by the contractile tendency of the stricture. With all due defference to the authority of this distinguished surgeon I think there is another class of cases in which external incision is still more appropriate. I refer to those cases in which we have urinary fistulae. My patient, Martin, belongs to this class. You may dilate his stricture, but the fistulae remain; by external urethrotomy you relieve the stricture, you open a new track for the urine, the fistulae close. Prof. Syme lays down the rule that permeability is an indispensable pre-requisite to the per- formance of external division, and yet, in his earlier life, on one occasion he introduced his grooved sound down to a stricture which he could not pass, opened the urethra in front of the contraction and then guided the instrument through and cut upon it. This operation has been repeatedly performed without the aid of the grooved staff, and often the very best results have followed. I will be able with this patient in a few days to intro- duce the instrument of Syme; upon this I will divide the stricture, and whilst the urine is flowing through the incision the adventitious urinary tracts will close. In concluding my remarks on this subject I would suggest the following rules for your guidance. 1st. Dilatation, for all uncomplicated strictures which can be passed by a sound. - 2d. Internal Urethrotomy for all strictures complicated with great irritability of the urethra or obstinate con- tractile tendency—those cases in fact for which Syme recommends perineal section. 3d. Eaternal Urethrotomy or Perimeal Section for all strictures associated with urinary fistulae. —-º-º-º- BE LILAIDONN A IFOR AIRREST ©IF MMANIMA RY SECRETHON. BY THAD. A. REAMY, M. D. Mastitis is no trivial affair; and mammary abseess is a calamity which every conscientious obstetrician will spare no pains in averting from his parturient patients. When the child is still-born, or dies soon after delivery, or from any cause cannot be put to the mother's breast, any means which will arrest the mammary secretion is at once a desideratum. Belladonna, if properly employed, generally proves itself an agent competent to such a result. The testimony of the profession, however, upon this point, is quite conflicting. I need not stop to quote the authorities pro, or con. They are well known to be pretty equally divided, as to numbers and credibility. Each founding his opinions upon clinical experience. My own testimony is authorized by observation of 22 cases in private practice; running over a period of 15 years. In 20 cases Suceess was perfect. That is, no amount of Secretion occurred which gave rise to any trouble. In Several cases no milk was secreted at all. In two cases the remedy seemed to exert no influence whatever. The milk tubes being fully distended within the usual time; in one of them intense inflammation su- pervened followed by abscess. It is but fair to state, however, that in this case the breast which suffered, had endured a similar experience at a former period, and, from the consequent changes of structure, had not re- covered. In my judgment three important items enter largely into the question of success or failure with the remedy, viz: Time when employed; Preparation of the drug; Manner of application. 1st, Time. The application should be commenced within a few hours after delivery. Usually from forty to seventy hours intervene between delivery and full establish- JAN. 6, 1872.] ment of milk secretion. During this entire time the remedy should be applied, as it is far easier to arrest the secretion in its incipiency than when under full headway; to prevent the filling of the lacteal vessels, than to dispose of their contents, and the coincident pain and inflammation, after they are already filled. The plausibility of this proposition seems to me sufficiently manifest without argument. But is enforced by the views, now most generally received, by those who have faith in the antigalactic powers of belladonna, as to its modus operandi. I refer to the explanation first given by Mr. Richard Hughes. Succinctly put by Stille as follows: “Belladonna both excites the sympathetic nerve and depresses the cerebro-spinal influence; wherefore its application to the breast diminishes both its secreting power and the supply of the material on which that power is exercised.” The same doctrine is well expressed in the following quotation which I make from my friend, Dr. F. P. Anderson of this city. “Belladonna being a powerful excitant of the un- striped muscular fibre, it diminishes the afflux of blood through contraction of the arterial and glandular tunics. Hence it does not act as a direct astringent, but as a stimulant neurotic and as indicated by counteracting the inhibitory influence of the vagus, it addresses itself to the sympathetic system. Its efficacy in constipation may be attributed to such an agency. - “In studying the effects of belladonna in iritis, we observe two important facts: First, that its external application may have a local effect only; when a weak solution is applied about the eye or to the conjunctiva, the drug expends its energy in the neighboring tract, and the phenomena following are confined to the eye treated. - - “Secondly, that in dilating the pupil and diminishing ocular tension—by relieving engorgement through exci- tation of the vaSO-motors—it operates specifically on the sympathetic nerves. Thus, when the drug is applied to the mammary region during the period of secretion, this localized and peculiar influence controls the greater supply of blood directed to the gland.” Second, as to Preparation. An aqueous solution of the alcoholic extract, say fifty grains to the ounce, is preferable to either the fluid extract or an ointment —for the simple reason that it is more readily absorbed. Third, as to mode of Application. Let it be applied with the open hand of the nurse over the entire gland, or still better, let strips of muslin saturated with the solution be applied and covered over with oil silk. Let all friction be scrupulously avoided as tending pow- erfully to excite secretion in the gland. - Finally, and for the same reason, let the breasts not be emptied of colostrum or of any milk which may have been secreted. Keep pups, pumps and nurses mouths away. No injunction, made will be more difficult to enforce than this, nurses will insist that “a part of the T E H C T.I.N.I. c. 5 milk at least must be abstracted. The breast. must dry up by degrees,” and yet, who does not know that for every drachm of milk drawn, six drachms will be secreted as a consequence of the abstraction. I may be excused for insisting with my professional brethren who may wish'to give the remedy a fair trial ; that if on the second or third day, as may often occur, there should be some general fever accompanied with more or less pain and fullness of the breasts, no alarm need be suffered; do not be driven to abandon the treat- ment, all those symptoms will subside in a few hours. In this connection I am informed by my collegue, Prof. Jas. T. Whittaker, who was for six months a pupil in the Vienna Gen’l Hospital, that it is the uniform prac- tice in that institution upon the intervention of the first symptoms of inflammation in a mammary gland, to wet nurse the child, and thus remove every source of irritation. And he saw no cases of mammary abscess in any ward of that immense charity. I am gratified thus to have attested by the experience of extended hospital practice, the truth of principles which I had Settled upon as the result of personal observation in private practice. I have spoken only of belladonna for arrest of Secretion in cases where desired. In a future article I shall give my experience with it, in the man- agement of inflamed and painful breasts where lactation was permitted to go on. - — ——º-o-º-––. -- RUPTURE AND wounds or THE stomLACH. BY J. Q. A. HUDSON, M. D. *msº [Read before the Meigs and Mason Academy of Medicine, Dec. 21, '71.] The almost total fatality of any injury of the stomach with solution of continuity of its coats, is such that our medical literature presents but a meagre record of cases of this lesion. This arises not only from the fact of but few recoveries having been known, but also from the fact that death usually rapidly takes place; leaving no items of interest in their history worthy of record. There is, generally, simply the stomach lesion, shock, and death in a short period, a few hours at the furthest. Rupture of the stomach without external violence, is extremely rare; while perforation from disease, though rare, is comparatively more frequent. I find the two following cases recorded of rupture without external violence. “Doctor d’Beauclair relates a case of a lying-in wo. man, who died on the fifth day after delivery, with all the usual symptoms of peritonitis. Thirty hours after her decease, the body was opened, and a laceration was found, four inches in length, in the lesser curvature of the stomach. The edges of the laceration were highly inflamed, and in a state of gangrene” (Atm. Med. Record, April, 1828, p. 419). 6 [JAN. 6, 1872. TIH. H. C. LINTI c. “In April, 1828, a man aged thirty-four years, was brought into St. Bartholomews Hospital, complaining of severe pain in the abdomen. Ten hours afterwards, he was seized with violent vomiting; the pain ceased; the vomiting also ceased; he died in five hours more, The posterior surface of the stomach was found lacerated, to the extent of three inches; and the contents of the stomach had escaped through the aperture; the mucous membrane was reddened, there was no thickening, ulcera- tion or any apparent disease of the stomach” (Taylor's Med. Juris., 1861, p. 282). - Rupture of the stomach from external violence is usu- ally accompanied by lesions of other abdominal organs. It is probably always fatal, the patient generally not surviving the shock. Mr. Poland relates three fatal cases of this injury. In one, death took place in three hours; in five hours in the second; and at the end of five days in the third; quoted from Guy's Hospital Reports (see Rankin's Ab- stract, July, 1858, p. 189). - There are no positive symptoms determining the ex- istence of this lesion, but it may be suspected, if the force producing the injury was received upon the upper part of the abdomen, and there is severe abdominal pain, great shock, and vomiting of blood. Haematemesis is thought to be an unmistakable symptom of rupture, and it probably generally is, if occurring in connection with the accident received, with the other accompanying symptoms; yet, haematemesis sometimes occurred in rupture or wound of the upper portion of the small in- testines. Haematemesis might also be supposed to arise from injury to the mucous coat without rupture, but I find no cases to support such a supposition. There would be a greater liability to the occurrence of rupture, if the violence were received when the stom- ach was full, as, after a meal, and the danger of effusion would of course be greater, as effusion generally in this condition arises. It is well known that effusion into the cavity of the peritoneum, is the great source of danger, in all injuries involving the continuity of struc- ture of the abdominal organs. When it occurs, the shock is intensified, and peritoneal inflammation is a cer- tainty, if the patient rallies and reaction is established. In rupture of the stomach the abdominal parietes are usually intact, or at least the integument remains whole, while in wounds of this organ the abdominal wall is also involved. The fatality in wounds is probably not so great as in rupture, yet in the former, recoveries are rare. We find a few instances of recoveries from wounds of the stomach, but I can find none, in which all the symptoms were present that are believed to indi- cate rupture. Cases of recoveries are found from exten- sive wound of the stomach. The protrusion of this organ through the wound in the abdominal wall, and the ef. fusion of the gastric contents externally, may be consid- ered favorable circumstances, when occurring at the time of the injury. The force required to produce rupture, without solution of continuity in the parietes, must be great, producing other internal injury and increasing the severity of the shock; while in wounds the force is less and it is spent chiefly upon the part directly wounded. ... • If there be no protrusion of the stomach, the existence of the external wound favors the escape of the gastric contents externally, and, if the stomach and abdominal wounds are by accident or otherwise maintained in apposition until surgical aid is rendered the probability of internal effusion is lessened. Effusion into the peri- toneal cavity does, however, often occur. Death in these cases may result suddenly from shock at the moment of injury. These cases may be classed with those in which death arises from blows on the epi- gastrium of which Prof. Gross gives an instance (see Sys, of Surg. 3d Ed., p. 598). The following is a case of sudden death from a gun- shot wound. A policeman was shot by a pistol bullet in attempting to arrest a robber “He almost instantly expired.” On post-mortem the only injury found, is given. “There was an aperture with blackened edges, of the size of a shilling, an inch below the juncture of oesophagus with the stomach on its posterior surface; and another cor- responding aperture on the anterior surface of the stomach, also at the cardiac end, but lower than the aperture on the posterior surface. No important blood Wºssel was wounded.” (See Am. Journ. Med. Sci., Cct., 1842, p. 487.) The proportionate number of recoveries to deaths in stomach wounds is very small. The ratio as given by Percy referred to by Jno. Watson, is undoubtedly too high. Watson says: “Injuries of this sort are, unquestionably, among the severest and most alarming; but their proportion of deaths to re- coveries is perhaps fully estimated by Percy, who calcu- lates that out of twenty cases only four recover.” (See Am. Journ. Med. Sci., Oct., 1844, p. 326.) Hamilton, (Mil. Surg., 1865, p. 358,) places the rate much lower, and is probably nearer the truth. He says: “The fatality of these accidents is even much greater than in similar wounds of the intestines. Probably not one in fifty recovers; perhaps not one in a hundred.” All authors agree as to the great mortality; but in the absence of statistics nothing definite as to the pro- portion of recoveries to deaths can be known. The rarity of the report of cases of wounds of the stomach in military practice, is another proof of the mortality; since it is probable that nearly all thus wounded die on the battle field. I can find but one case of recovery from wound of the stomach occurring during the late war. There may be other cases reported, since my material for reference is not extensive. On post-mortem after wounds of the stomach, there is usually found a greater or less amount of foreign matter in the peritoneal cavity; such as blood, chyme, un- digested food, etc.; the existence or not of peritonitis depending upon the time of death in relation to such. JAN. 6, 1872.] TIEEE E CIT, IIST.I. C. 7 If death occur during the period of shock, but little in- flammation will be found; if the period of reaction has been some time passed, evidences of peritoneal inflam- mation will be more marked. * Notwithstanding the oft repeated statement that there is no peritoneal cavity as such, and that by the action of the muscles and atmospheric pressure, the cavity can not exist strictly speaking, yet, the contents of the stomach under certain circumstances (as well as those of the intestines,) and the contents of the blood vessels do get into the peritoneal cavity; the cavity being filled as much after the effusion as before. The abdominal contents are the same, there is simply a change of position or relation. Although the equable pressure of the abdominal parietes, keeping the viscera in close apposition, is a favorable condition to prevent effusion, yet is too often inefficient, as repeated post- mortems in wounds of the stomach and intestines have abundantly shown. The probability is, that Gross is nearer the truth than was Franro' or Jno. Belt, or B. Cooper, when he states that in the majority of cases of wounds penetrating the stomach or intestines there is effusion into the peritoneal cavity. The circumstances that favor absence of effusion are as follows: º 1. The concurrent protrusion of the wounded pºrt at the time the wound is received. The effusion is then external, and the surgeon can command the wound to prevent to a great extent, if not wholly, future effusion into the cavity. 2. Apposition of the wound in the tube, with the wound in the abdominal wall. If this apposition exists, and is maintained, the contents of the tube escape inter- nally if at all. 3. A quiescent state of the body and of the bowels im- mediately after and following the injury. 4. An empty condition of the wounded part of the tube at the time of the accident. The symptoms denoting wound of the stomach are the same, (though || sometimes less in degree,) as those of rupture. There are symptoms of shock shown by pallor, faint- ness, weak and frequent pulse, excessive pain in the abdomen, nausea and vomiting; and sometimes vomit- ing of blood. Haematemesis is considered as diagnostic; but it is often absent. The stomach may be wounded at a point including one of its principal blood vessels, or it may be wounded where no important blood vessel is included. So that although this symptom is valuable when present, with tolerable certainty denoting wound of the stomach, its absence is of no value to show that it is not wounded. Where the wound in the stomach cannot certainly be known by inspection, the situation and direction of the wound, the extent of penetration of the instrument may aid in the diagnosis. Symptoms of shock are not invariably present as in many of the cases of necrosis where the stomach was known to be wounded shock was slight or entirely absent. The same remark applies to nausea and vomiting. The symptoms indicating unfavorable prognosis are excessive shock, especially if of long duration ; vomit- ing of blood, especially if this should continue; as its persistency will point to the wound of some important blood vessel; a full state of the stomach when wounded, as this condition favors effusion; and after the reaction is established the supervention of peritonitis; especially if it is supposed to be caused by, or connected with, effusion into the peritoneal cavity. Before entering upon the treatment of wounds of the stomach I will present a summary of the cases of recovery so far as I have been able to collect them from the literature at my disposal. We may possibly be able to deduce some conclusions from them in regard to treatment. [To be continued.] —sº-º-º- A Case of Congenital Fissure of the Lids. BY W. W. SEELY, M. D. * sº-sº From the Transactions of the American Ophthalmological Society of July, 1871, just published. Freaks in embryological development are interesting as curiosities, and instructive when studied in connec- tion with the normal growth. The case I have met with presented abnormalities in both lids, and also in the ball. Beginning at the outer angle and following the lower lid toward the inner angle, we found the development perfect for about three-fourths of the length of the nor- mal lid. Then, by a pretty steep angle of declension, the lid terminated with a channel, through which the tears flowed upon the cheek. The remaining fourth of the lid was found as a piece of skin, of an irregular, in- verted V-shape, closely attached to the globe, extending to near the sclero-corneal junction. The upper lid extended, with perfect development, to a point corresponding to the beginning of the defect in the lower. Here there was a slight notch; then the free margin was continued on to the inner angle, but without cilicilia, or Meibomian glands, so far as I could discover. There were, also, no cilicilia on the angle ofter- mination in the lower lid, none upon the fold of skin attached to the globe. Nor we terhere any Meibomian glands in this attached portion, and no cartilage. There was likewise no trace of the inferior canaliculus. Dr. Wecker has given a description of a case of con- genital fissure of the lid (see Arch. für Ophthal, und Otol., vol. i.), and has referred to nine others. - So far as I can discover, the case I have described is peculiar in this, that there was a very large portion of skin attached to the globe. This portion, however, did not fill up the defect when the lids were closed, for a space was still left between the lid proper and the ad- herent portion. With the exception of this adhering part, the eyeball was perfect. T H E CITISTI c. [JAN. 6, 1872. I have seen one case of slight notching of the upper lid, occurring in a child affected with a single harelip. Also a dermoid tumor about the sclero-corneal junction, without any coloboma of the lids. The child whose case I have described had a suspicion of defect in the upper lip, and also of the alveolar pro- cess. The lip seemed to be thinned in front of each nostril, the fact becoming quite apparent when the child cried and the lip was stretched, - According to Kölliker (see “Entwickelungs Geschichte des Menschen und der Höheren Thiere”), we have the sclerotic and cornea appearing in the latter part of the second and first part of the third months. The eyelids begin, as small folds of skin, about the first of the third month; come into contact and unite in the fourth. It would seem, according to the pointing of some of these cases of defects, that, along with the formation of the lids, there must also take place a histological trans- formation of the skin covering the eyeball, into two layers of mucous membrane; the one, the palpebral, the other, the ocular conjunctiva, Continuing our reasoning with this view, we are of course forced to regard these colobomata as simply ar- rests of histological transformation. - As regards the operative interference, I would simply add that the first step was to free the movements of the ball, which of course were very much restricted by the cuticular attachment. To accomplish this, I dissected the attached portion loose, down to the level with the cul-de-sac, and snipped it off. Then, by loosening the conjunctiva a little, and making two incisions along the cul-de-sac, on either side, it was readily brought together over the denuded spot and held by two sutures. Two weeks later, I prepared the parts, denuding them up to the inner angle, also the lid, and, by making an incision horizontal to its free margin, carried it forward and fastened it. - - - It fitted nicely, and remained three days, when the mother brought the child in, saying she had torn the parts loose. Subsequent attempts failed to keep them together, - —º-e—º- scLENTIFIC NoTEs. General Physiology of Virus and of Infectious Diseases. BY M. CHEAUVEAU, Prof. Physiology at Lyons, Conclusions of an exhaustive memoir presented during the Cours Publics, from the Gazette Hebdom, Nov. 17, 1871, We have now finished, gentlemen, this investigation of the ultimate causes of infectious diseases. We may recapitulate now in the determination of the necessary distinctions in rendering our subject accurate and pre- C159, * - Among contagious diseases there is a large category properly called parasitic, due to the presence of animals or vegetables which multiply by direct alternate gen- eration; maladies in which the animals or vegetables act only by the local irritations and destructions which they induce. In these maladies if the parasites be very small or of nature but little aggressive or if they do not attack organs of great importance, their presence may be compatible with an almost perfect state of health. When they exist in reverse conditions they may be fatal. Examples: The trichina muscularis, the psoro- sperm of the silk worm, the hepatic douve, etc. Properly considered, these must be admitted in the category of infectious diseases, - - Another division of contagious affectious of parasitic nature forms the class of septic or septicoid diseases, which in the existing state of our knowledge are to be considered as produced by the rapid multiplication in the blood of organic ferments whose action is to induce a kind of poisoning of the nutritive fluids in greater or less degree according to the character of the poison, the condition of the individual, etc. These affections may complicate infectious diseases proper but should not be confounded with them. * * * Finally, a last class of contagious diseases comprises the infectious diseases proper, our subject of study: dis- eases whose symptoms do not correspond to those caused by direct action of parasite ferments. * * * In these diseases the entity of the contagium does not reside in the fluid elements of the juices containing the poisonous elements. This is absolutely determined. The plasma or the serum in which the granular ele- ments float is perfectly inert when deprived of these granules. The granules alone are the exclusive agents of infection. In regard to the origin and development of these agents we may say that the ultimate cause of the infec- tion resident in these minute masses of protoplasm is derived from the contact of germs themselves already infectious and capable of inducing similar properties in the bodies with which they come in contact, —sº-9—sº--— MEDICAL NEws. SKoDA has just received another ovation in Vienna, CHOLERA persists in Turkey. According to the Vienna Medical Press Dec. 10, the victims of the past week alone number 277. - THE BERLIN BATTLE-From a recent letter we learn that a doctor's quarrel of magnificent proportions is now raging in Berlin. The signal for the fight was the appointment of Frerichs as Lehenrt's successor to the position of Director of the Science Deputation, a body created in 1817. Profs. Langenbeck, Martin and Virchow have interviewed the minister of instruction, and highly explosive paper missiles have bsen discharged on all sides, Virchow's open declaration that Frerichs JAN. 6, 1872.] TEEE CITINI c. was not the proper person to fill such a position has |. created a profound sensation. In comment upon this statement the Vienna Medical Press remarks that “Such an expression from Virchow could only depend on facts, and these facts meet with confirmation when we reflect that Frerichs has done nothing in science, little or nothing in literature, for a very long time indeed, notwithstanding his various positions and his earlier labors. It is very well known that Frerichs has never been dearly loved as consulting physician, but there must be other reasons for this strong opposition against him which will be disclosed, no doubt, with time. ... • . . . . - * PHYSIOLOGICAL LABORATORY FOR ANIMALS.—A hos- pital is just opened in South London for the study of the diseases of the domestic quadrupeds and birds. A certain Mr. Brown of Dublin has endowed the hospital with £30,000. Eccentric as this expenditure might seem to be at first sight a moments reflection will re- veal the great value of such an institution in the new light it will cast upon the pathology of the diseases of man with whom the lower animals have so many af. fections in common. The direction of the hospital has been entrusted to the distinguished Burdon Sanderson of University College, and he has called to his assis- tance Dr. Klein of Brücke's laboratory in Vienna. DANGERS OF AN ECLIPSE,--The following edict was actually published in 1699, by the Elector of Darmstadt, in view of the approach of a total eclipse of the sun : “His Highness having been informed that on Wed- mesday morning next, at ten o'clock, a very dangerous eclipse will take place, orders that on the day previous, and a few days afterwards, all cattle be kept housed, and to this end ample fodder be provided; the doors and win- dows of the stalls to be carefully secured, the drinking wells to be covered up, the cellars and garrets guarded, so that the atmosphere may not obtain lodgment, and thus produce infection, because such eclipses frequent- ly occasion whooping cough, epilepsy, paralysis, fever, and other diseases, against which every precation should be observed.”—Scientific American. - THE TITLE OF “DOCTOR,”—The title of “Doctor” was invented in the twelfth century. Irnerius, a learned professor of law at the University of Bologna, induced the Emperor Lothaire II., whose chancellor he was, to create the title, and he himself was the first recipient of it. He was made doctor of laws by that University. Subsequently the title was borrowed by the Faculty of Theology, and first conferred by the University of Paris on Peter. Lombard. William Gordenio was the first person upon whom the title of Doctor of Medicine was bestowed; he received it from the College of Asti, in 1329,-N. Y. Med. Gaz. ". SMALL-Pox in BERLIN.—The present epidemic of Small-Pox in Berlin has already reached enormous pro- portions. Up to Dec. 10,9000 persons had been attacked, CLINICAL MEMORANDA. .*. 1HYPopFRMIC INJECTION OF MORPHIA.—Mr. J. P. Sleightholme gives(The Practitioner, July, 1871) the re- sults of his experience with this mode of medication de- rived from two thousand injections of morphia while house physician to the Manchester Royal Infirmary. He says that with one exception, he never saw any im- mediate ill-effects from it, and only in one case, any great evil result from its prolonged use. He seldom found it necessary to increase the dose beyond one-fourth of a grain. In conclusion; he says, “that when hypodermic injections of morphia were used with intention of re- lieving pain, they almost invariably succeeded in doing So, no matter how severe the pain might be; that when sleep was prevented by severe pain, the pain was re- lieved and sleep generally followed; but that when sleep- lessness depended upon or was accompanied by great ex- citement or delirium—as in mania, delirum tremens, acute chorea, &c.—the injections not only frequently failed to produce sleep, but were often followed by in- creased excitement and delirium.”—American Journ. of the Medical Sciences. - “Hernia puncture, a New and Easy Mode of Treat- ing Straugulated Hernia. Purancture for Abdom- imal Tympanites. Puncture of the Bladder for Re- tention and Infiltration of Urine.” The following discussion in the French Academy the report of which we find in the Edinburgh Medical Journal for December, 1871 is exceedingly interesting, and peculiarly so to us from the fact that in our neighbor- ing city, Louisville, three cases have been reported wherein the “New and Easy Method” has been resorted to, and with somewhat of success. These cases occurred in the practice of Drs. David Cummings and Douglas Morton, and have been reported in the Richmond and Louisville Medical Journal, by Dr. Morton. (See that journal for Sept. and Dec., 1871.) “Case of Strangulated Hernia, in which the intestine was punctured and air withdrawn, with remarks and discussion. –M. Dolbeau reports the following case:—B., aet. 59, entered hospital for the treatment of an aggravated con- dition of disease of the heart. He also had a reducible hernia. This, some days after admission, without any Special reason, became painful, and the patient soon showed all the classic symptoms of strangulated hernia, and was sent to the surgical wards of M. Dolbeau. The heart symptoms were by this time very urgent and alarming. This hernia was as large as a turkey's egg, in scrotum and in inguinal region, painful, hard, and resonant to precussion. 10 [JAN. 6, 1872. TEEE CI.I.INTI c. “The patient seemed so weak that M. Dolbeau thought it useless to operate, but next day (the fifth since any facal evacuations had been obtained) the patient was a little better, so that M. Dolbeau thought of trying puncture and tapping of the intestines. Two punctures were made by the smallest needle of M. Dieulafoy's in- strument, the first obtained only some reddish fluid mixed with fæces; the second also a quantity of fluid. The tumor was diminished in size, and taxis succeeded in reducing more than half of it into the abdomen; the remaining half was not painful, and seemed omentum only. Faradization of the abdominal muscles was then used, and in four hours a stool was obtained, which was soon followed by a second. The patient unluckily died of his heart-disease in the evening. An examination of the body showed that the hernia had been reduced, and that the puncture of the intestine had not caused any communication with the peritoneal cavity. The portion of intestine was removed and inflated with air; not a single bubble of air escaped, and the intestine remained distended. - “M. Boinet remarked that he had never performed the operation of puncture for hernia, but had often done it in abdominal tympanitis, even five or six times in one month on the same individnal. He had never seen any harm result from the punctures, which were quite inno- cent if performed with a sufficiently fine needle. Air and fluid can escape without causing effusion into the peritoneum, as the little aperture is at once closed by the contraction of the walls of the intestine. “M. Lábbé thought M. Dolbeau's communication very interesting. M. Dieulafoy's instrument was better suited than any other needle or trocar. He had done it in a case of peritonitis after ovariotomy, and there was no peritoneal effusion. He had on another occasion made a different use of the needle. A patient had re- tention of urine, and an enormous infiltration of urine in the perineum. The catheter could not be passed, but by the syringe the water was completely drawn from the bladder. After death the puncture was found to leave no trace of its presence, nor to have caused any escape of urine. “M. Tarnier referred to a paper he had published, in which he had recorded several cases of intestinal strangu- lation treated by puncture of the intestine. “M. Giraldes referred to a sealed packet which he had some time before deposited with the president, in which a series of observations on puncture of the intestine in strangulated hernia were recorded. He had often done it, both in children and adults. “M. Blot had punctured the intestine with a flat needle so long ago as 1855, in a case in which caesarian section had been performed, and peritonitis with disten- tion had occurred, and a lump of intestine had protruded. This could not be returned from its size till punctured. The patient died next day. Yet no trace whatever of effusion into the peritoneum from the needle-wounds could be found. It is possible to puncture the intestine with a fine instrument without any danger of effusion into the peritoneum. '. - “M. Verneuil had never performed the operation, and had some doubt of its efficacy on physiologico-pathologi- cal grounds. The intestine in these cases is paralyzed as well as strangulated, and the puncture would not have any effect in remedying the paralysis. The sub- ject gives an opportunity of mentioning a method of the taxis in which compression of the neck of the sac is added to the ordinary pressure on the hernial tumor itself with great advantage. “M. Trelat related two cases of hernia he had recently operated on with success after eleven and fifteen days of strangulation respectively. How to account for such an unexpected result?. His opinion was, that in these cases the patients had not really suffered from strangu- lated hernia, but from hernia in which adhesions be- tween the bowel and omentum had caused an arrest on the course of the faeces. Gosselin, in his Lectures on Hernia, describes adhesions, but thinks that they are rarely causes of accidents, as they are almost always soft, and merely the result of the peritonitis which accompanies the strangulation. In my two cases the intestine did not show the ring which generally is caused by the neck of the sac, but had adhesions which caused me to separate bowel from omentum by a careful and delicate dissection. The adhesions bled when separated in the first case so as to require perchloride of iron, and the second to resist even that styptic, and to require the use of the hot iron to several bleeding points. “M. Lábbé thought M. Trelat’s cases most important, and he agreed with him in his pathology. He had operated with success in a female of 82, in Whom he had to dissect many adhesions between intestine and omentum, which bled so much as to require perchloride of iron. He described another case in which symptoms of strangulation had gone on to a fatal issue, with- out the existence of real strangulation, but only the presence of adhesion between bowel and omentum. “M. Giraldes had lately seen a case of hernia in which the intestine had been strangulated in a sac of omentum. Had this been reduced en masse the patient would have been unrelieved. This condition had been recognized and well described by English surgeons. “M. Liegeois described a case in which he had opened a cavity from which gas with a faecal odor escaped, so that every one thought it was intestine, and the edges of it were stitched to the wound. The vomiting con- tinued, no faces escaped, and a future operation showed that the bowel had not been opened at all, but that it was gangrenous from being tightly strangulated by the cribriform fascia. - “M. Despres mentioned a case of hernia in which Boyer had opened skin, sac, omentum and bowel at once, they being all thin and adherent. Without destroying the adhesions or reducing the hernia he stitched up the wound, and the patient got well. The accident which M. Liegeois described had happened to many good surgeons. Gazette des Hôpitaua, Nos. 73, 75.” JAN. 6, 1872.] TIEEE E CIT, I N T C. 11 Puncturing the walls for pneumatosis has been per- formed so frequently of late and with such success that it is now established as a legitimate measure. Fonssa- groes has reported almost one hundred cases collected from his own and from the experience of others. This city furnishes several cases in which it has given great relief. “Hernia puncture” as Dr. Morton calls the operation for the relief of a strangulated bowel is hardly yet upon its trial—but few cases have been treated by this method. M. Tarnier it will be seen refers to a paper of his in which are “recorded several cases of in- testimal strangulation treated by puncture of the intes- time” but he gives no data of the success of the treat- ment. M. Giraldes is equally unsatisfactory in his mere reference to his sealed package in which is recorded his experience, M. Huguier, however, has invented an instrument to prevent the escape of gas and feces into the peritoneal cavity, and with this instrument he has successfully treated strangulated hernia. - No notice is taken of this treatment in either of the three fresh surgical works now on the table before us, viz: Grant's Science and practice of Surgery, Spence's Lectures on Surgery and Ashhurst's Principles and Practice of Surgery; the first and the last bearing, re- spectively, dates September, 1871 and November, 1871. It would seem from the silence of these three works that M. Tarnier's paper on “Hernia puncture,” has not had a very extensive circulation. The first case given by Dr. Morton was operated on by Dr. David Cummings, in November, 1869. The patient was a negro boy with a large strangulated scrotal hernia. “The instrument employed by Dr. Cummings was a hollow needle, made for applying sutures in vesico-vaginal fistula. Immediately on in- troducing this instrument, the gas which distended the bowel, gushed out, relaxing the walls of the loop and rendering reduction a matter of the utmost ease. The patient was up on the next day, and suffered no bad re- sults from the operation.” - In the second case, (an old hernia that became strang- ulated during a fit of coughing) Dr. Morton used “the nozzle of a hypodermic syringe.” He drew off some flatus, and with the syringe pumped out some fluid; but could not succeed in reduction. During an hour's absence (in which he was making arrangements for herniotomy) spontaneous return of the bowel occurred. Dr. Morton reports this case to show that no bad effects follow the puncture of the bowel. The third case we infer was successful. Dr. Morton used a small trocar and canula, and had an erysipelartous inflammation following the puncture, which he attrib- uted to the escape of fluid into the subcutaneous cellular tissue. To prevent this he advises a canula needle tapering from heel to point. - , Equally suggestive is the case reported by M. Lābbé, in which he with the smallest needle of Diénlafoy's in: strument relieved a dsstended bladder. After the death of the patient no trace of the puncture was left. sion, and pain of the inflamed skin. MoRPHIA HYPODERMICALLY IN ERYSIPELAS.—In the Deutsche Klinik, No. 39, is a paper from the pen of Professor Estlander, of Helsingfors, upon “The Subcu- taneous Injection of Morphia in Traumatic Erysipelas.” He states that he employed this injection originally in his clinical practice, in combination with the so-called abortive treatment (chiefly by means of tincture of iodine), mainly with the view of relieving the heat, ten- It was soon found, however, that the morphia must have exerted other ef- fects also, so quickly was the course of the disease mit- igated. It was therefore used in a series of cases as the sole local remedy, and the conviction became establish- ed that it must have exerted a direct influence on the inflammatory process, diminishing its intensity and ar- resting its progress. When the limits between the in- flamed and healthy portions of the skin are not very clearly defined, and the process manifests itself in the form of large red spots gradually approaching each other if we inject near the affected parts we usually find next day that the erysipelas has not extended farther, or has done so only to an insignificant extent. In cases in which the limits of the reddened and swollen skin are well marked, if we make some injections in its vicinity, we may find that the inflammatory process, which during the preceding twenty-four hours had made con- siderable progress, is sometimes at once arrested, but more frequently it continues in a diminished degree, gradually yielding in the course of a few days to a con- tinuation of the treatment. In the worst cases of erysipelas ambulans, as in the se- vere epidemic form, or where a peculiar disposition of the individual prevails, the morphia exerts as little effect as any other of the so-termed abortive remedies. In es- timating how far the results depend upon the peculiar nature of the erysipelas itself, and how much they are ascribable to the injections, Professor Estlander has un- dertaken many comparative trials, and he could relate many cases in which, while a rapid improvement fol- lowed the use of morphia, other cases treated at the same time, either expectantly or by means of other rem- edies, were much slower in their progress. Still, he is too well aware of the capricious character of erysipe- las to venture to deliver any categorical judgment upon the subject. But a five-years' experience has convinced him that these injections constitute a better mode of treating erysipelas than many other means. For the injections, two grains of the cholorate or acetate of morphia are dissolved in a drachm of water; and as Luer's syringe holds about a quarter of a drachm of which a quarter or a half is injected, it follows that the dose varies from one-eight to one-quarter of a grain. As, so far from the erysipelas ever appearing at the small puncture-wounds, these and their immediate vicin- ity are always respected by it, the dose may be distribu- ted over different º of the healthy skin, at a distance of one or two inches from the limits of the inflamma- tion. Usually the injection is made only once in twen- ty-four hours. 12 [JAN. 6, 1872. TH. H. cI, IISTI c. Professor Estlander has no intention of proposing this as an exclusive method of treating erysipelas, believing, on the contrary, that one of its advantages is that it ad- mits of the simultaneous use of other means. He has tried, indeed, all the various other remedies which have been recommended, and regards the tincture of iodine as the best of these. As soon as from shivering and the appearance of the wound erysipelas seems threatening, he administers an emetic, a means which he believes is nowadays too much neglected, and one which he be- lieves conduces to moderation of the disease. The mor- phia is next injected, either as the sole means or in con- junction with a daily painting with iodine, employing afterward wadding and compression by a roller where practicable. Ipecacuanha with phosphoric or sulphuric acid may afterwards be administered. The sesquichlor- ide of iron, once regarded as a specific, is of no real utility.—Times and Gaz., Dec., 9 '71. - —- sº-º-º- HoME NEws. LECTURES were regularly resumed in the College on Thursday morning last. The long pull on the home stretch commences. THE hospitality of the Good Samaritan was thoroughly tested last week on the occasion of a visit to the institu- tion by a large number of the most prominent eitizens of our city. The entertainment is said to have been the affair of the season. DURING the past year 2,752 patients have been register- ed and treated at the Dispensary of the Medical College of Ohio. THE most complete and elegant electrical apparatus in the U. S. is now being fitted up in the Good Samar- itan Hospital. Constant and Induced Currents,Galvano- Cautery, all manner of machinery in the electric art is ordered without regard to expense. The electric cham- ber with all its appliances is a gift—the private munifi- cence of a citizen of Cincinnati. THE medical sensation of the week has been the Lawler will case now being argued in our courts before Judge Cox. The question concerns the validity of a will made by Mr. Lawler in advanced life when the contestants claim, degenerative changes were present in marked degree, as evidenced by the post-mortem exami- nation as well as by collateral testimony. The lawyers on both sides refresh themselves after the severe labor of the day with light reading on medical subjects, more particularly with the latest novels on the anatomy, physiology and pathology of the brain Any points of general interest elicited will duly appear in The Clinic. TO THE REALDERS OF ** THE cLIN1c.” The termination of the first volune is a suitable occa- sion to review our work for the past six months, and to indicate our plans for the future. We think we may claim for THE CLINIC that it differs from other medical journals of the United States in its strictly practical character. The original contributions which have appeared in its pages have had the aim to afford some definite information to our readers, and have been as free as possible, we think, from that prominent defect of journalistic literature, the publication of papers pre- pared by their authors for the gratification merely of the cacoethes scribendi. Whatever excellence the original articles of the first volume may have possessed will certainly be sustained by the contributions of the future, some of which are promised us by the most dis- tinguished writers of the country. In this original de- partment it is proposed hereafter as heretofore, to dis- cuss the questions of the hour. Our pages will always be open to fair and candid criticism upon medical ques- tions, but merely personal controversies will under no circumstances be admitted. The department of selec- tions will contain as heretofore the cream of foreign literature. Our readers must have observed, me may | remark in this connection, that THE CLINIC usually anticipates all other journals of the United States in the publication of the discoveries and improvements in medical science. Hitherto our selections have been made chiefly from German, French and English sources: our facilities in this regard are now materially increased, and hereafter the medical literature of the other languages of Continental Enrope will be laid under contribution. Our readers may depend upon it that THE CLINIC will keep them en rapport with modern medicine. As a large subscription list will enable us to carry out these objects more perfectly we hope our friends will interest themselves to increase the circulation of THE CLINIC. State Medical Society. The following Special Committees are to report at the ensuing meeting in Portsmouth, on the second Tuesday of June, 1872, Uterine Therapeutics—H. J. Herrick, Cleveland; Ovariotomy—A. Dunlap, Springfield; Eye and Ear Sur- gery—W. W. Seely, Cincinnati; Vaccination—W. B. Davis, Cincinnati; Nervous Transmission—S. S. Scoville; Generation—J. T. Whittaker, Cincinnati; Puerperal Convulsions—J. Pomerine, Cincinnati; Pathology of the Blood—W. P. Thornton, Cincinnati; Therapeutics of Mineral Springs—G. E. Walton, Cincinnati; Therapeu- tics of Electricity—R. Bartholow, Cincinnati; New Rem- edies—E. R. Lang, Portsmouth; Gynaecology—C. D. Palmer, Cincinnati; Chronic Diseases of the Lungs— Wm. Carson, Cincinnati; Hernia Cerebri—P. S. Conner, Cincinnati; Obstetric Records—J. Helmick, Cleveland; Castration—W. C. Hall, Fayetteville; Electrolysis—W. H. Mussey, Cincinnati; Cholera Infantum—A. J. Miles, Cincinnati; Amputations—T. H. Kearney, Cincinnati; Belladonna—J. A. Little, Deleware, Ohio; Diseases of the Larynac—R. Wirth, Cincinnati; Uterine Diseases— E. B. Stevens, Cincinnati; Diseases of Skin—C. O. Wright, Cincinnati; Surgical Diseases of Women—T. A. Reamy, Cincinnati; Medical Chemistry—J. B. Hough, Ridgeville; Puerperal Insanity—R. Gundry, Dayton ; Prevailing Diseases throughout the State—J. R. Black, Newark; Inflammations of the Chest—J. A. Murphy, Cincinnati; Semiological Value of Yellow Elastic Tissue in Sputum—A. T. Keyt, Cincinnati; Relation of the Mental to Man's Physical Forces—A. B. Jones, Ports- mouth ; Asylums for Epileptics—W. J. Conklin, Byron Station, W. L. Peck, R. ºnary ; Pschycology—J. W. Hadlock, Cincinnati, DIVIDED MEDICINES, The Divided Medicine Com’y, CINCINNAT1, OHIO. 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Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE TO SPOIL BY ANY LENGTH of TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calls with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. For samples, Price Lists, and Agencies, address The Divided Medicine Co., - IECX 2688, Or FRFDERICK KRAUS, Chemist and Druggist, : - - •. & * Walnut Hills, Cincinnati, O. MR. FREDERICK KRAUs: - CINGINNATI, February 15, 1871. Dear Sir—The specimens of your “ Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: . w - SULPH:MORPFIII........ % grain in each square ARSEN:ACID 1 & ſº º::::...º.º.”--------------------- . * *A*. * * * * * * * * * * * * * * * * * * * * * * * * c e a e s a e e -20 te - . + Čºrts ºf...ſº & © . & 4 qū - CALOMISL..............................}4 grain in each square. COPPER........................ % § { • Zºº y RESPECTFULLY You Bs, E. S. WAYNE, Analytic Chemist. F. E. SUIR 7, E. S. WAYNE TT. THC. Suire & Co., WHOLESALE DRUGGIST's, INAL A. INT TJ ET AL C T TU TER, I INT G- £Hemists AND FHARM aceutists, CINCINNATI, OHIO. Have constantly on hand a full assortment of sex.x:cºexex, ox{UGs ANYO Ivocoxc)(N)es, cºrvo, CA), AºA)3A%us, TEST5, MEDICAL, GLASS WARE, &c., &c., And solicits the patronage of the trade and profession. We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, | “, Made in accordance with the U. S. P. and other recognized authori- ties. E"INFC ANTD EAERIHC CEDEMICA LS, Of the popular class of preparations known as II, T, IIXIIIHR, S, We manufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. Bitter Wine of Iron, An excellent Chalybeate and tonic, Wine of Iron, &c. AGENTS FOR BULLOCK & CRENSHAW'S Sugar-coated Pills and Granules. Price Lists of preparations and of Sugar-coated Pills sent by Mail upon application. 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Special attention paid to orders for Fine Microscopic objects and *rºcopº Apparatus, Magnifiers and Readers in great variety. edical Batteries, Barometers, Thermo- meters, Hygrometers, Urimometers and Rain Gauges, of the most approved construction always on hand. All orders promptly and accurately filled, JAS. FOSTER, JR. deali F. S. SHACKLEFORD, } *** * JAs. Foster, J.R. & Co. S. W. Cor. Fifth & Race Sts., Cincinnati, 0. TXIPR). S.INT-TM A-TE,SIET’S -º-N ºs-- No. 758 BRoadw AY, New York I HAVE been in the habit of applying and recommending the Truss manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined. LEWIS A. SAYRE, M. D. Surgeon, Bellevue Hospital. From Prof. Willard Parker to S. D. Townsend, M.D., Surgeon to the Massachusetts General Hospital, BEG leave to state for the benefit of all concerned, that I have known Dr. S. N. Marsh the last fifteen years. * * * I am in the constant habit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of 'Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with any of the risks to the patient that exist in many of the plans suggested and attempted to be carried into execution. I have confidence in Dr. Marsh as a gentleman of honor and integrity, and as such recommend him to the members of the medi- cal profession generally. WILLARD PARKER, M. D. Professor of Surgery, New York City Dr. S. N. Marsh's Patent Radical Cure Truss, and all other kinds of Trusses, Shoulder Braces, Supporters, Elastic Stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Oure Truss Offices of S. N. MARSH & CO., No. 2 Vesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. OPPOSITE THE HIGH STEEPLE, William Autenrieth, No. 71 WEST sIXTH stre+ET, Bºwiń walnut in WWE, sº CINCINNATI, OHIO, MANUFACTURER OF AND DEALER IN III, III III, III. Abdominal Supporters, Trusses, CLUB-FOOT SHOES, SPINAL APPARATUS, ETſ Keeps constantly on hand a full variety of Metalie and Rubber Syringes, Stomach Pumps, Etc., stockINGs Fort waſticose veins. Special attention given to the fitting of Apparatus for Deformities. Bºy Agent for DR. L. A. BABCOCK'S silver uterine Supporter, -ALSO- DR. AHL's POROUS FELT SPLINTs, •-ALSO- D A. 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Surgical Batteries, for Coutreization, of any size ordered. © THE RHEon Egos, or cuRRENT GUIDE, Patented February 1st, 1870, is an entirely new contribution to Science, by which total interruption, alternate connection and interruption, of inversion or the polarity of the current, is obtained by a mere pressure of the finger. We also manufacture Carbon or Gilt Steel Point Electrodes; Eye, Ear, Phrenic Nerve Electrodes; Catheters for Urethra and Uterus; Electric Scourges, Foot Plate, Tin or Carbon, Wires with or without Trocars. for resolution of Tumors, Tongue Plates, Rubber tubing, Battery fluid, &c. &c. Please call and ex- amine, or send for Circular to The Galvano-Faradic M'f'g Co., No. 167 East Thirty-fourth St., Cor. Third Av. New York, OPINION OF PROF. DOREMUS. College of the City of New York, cor. of Lexington Avenue and 23d Street, New York, November 7, 1870. J have carefully examined your new Electro-Magnetic Machine, with its valuable and ingenious improvements. I consider the In- 8t?"ttºment the most complete, the most varied in its applications, and most convenient I have ever seen. R. O.G.D.E.W DOR EMU.S. Late and Important Improvement.—Patent applied for. The Ex- celsior Machine Rendered Portable. Can now be carried around by city or sountry Physicians, charged and ready for use, without the posibility of spilling the Battery Fluid. ROBT CLARKE & Co. ~ PUBLISHERS, |||}|{&\ſill; Call the attention of the Medical Profession to their Externsive Stock of &nglish, 31ſtrican aud french wrozcºz moors. Paying particular attention to this branch of their business, they are enabled to execute all orders on the shortest notice, and at the most | reasonable rates. Their facilities for the impor- tation of FOREIGN BOOKS, THE PROCEED- INGS OF SOCIETIES and HOSPITAL RE- PORTS are unsurpassed, and any orders en- trusted to their care will be filled promptly, and at the lowest rates. Subscriptions received for FOREIGN and AMERICAN PERIODICALS. All the New Publications received as soon as issued. - Letters of Inquiry will receive our prompt and full attention. Catalogues furnished gratis on application. ROBERT CLARKE & Co., lºwhilºlº, mºulilº; PRINTERS AND BLANK BOOK MANUFACTURERS, 2eaders in Zaze,_Medical, Zheological, School, azed.2/?scellaneous Zooks, G & TVVest CINCINNATI, O. Fourth street, J. Taft. w. TAFT. Editor Dental Register J. & W. Taft, TENTIST's 17 WEST FOURTH STREET, . CINCIN NATI, O. #: Registers § ºxº A Monthly Journal, CONTAINING 48 PAGES, Devoted to the Interests of the Dental Profession, arosTER’s, Are furnished to Officers, and Soldiers on Government account. • * - I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMEs A. FOsTER, 911 (Shestnut Street, Philadelphia, Pa. No. 60 West Fourtin street. Cincimamati, Ohio, or 172 Jef- ferson Avenue, Detroit, Mich. HE C LINI C. PUBLISHED EVERY SATURDAY. T E R MIS-$2.00 a. Year, Invariably in Advance. All Communic ations relating to Publications must be addressed to the Editor : All Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer. Vol. 2. C IN C IN N A TI, J A N U A R Y 13, 1872. No. 2. *, ** ** *śs. T. whitra KER, M. D. No. 101 West Ninth Street, Cincinnati. - - - Editor. ...A-SSOCI-A-TIE EIDITOR.S. W. W. D.Awson, M. D. ThAD. A. REAMy, M. D. P. S. ConneR, M. D. C. D. PALMER, M. D. *W. W. SEELY. M. D. SAMUEL NickLEs, M. D. ºHAs. KEARNs, M. D. JNo. L. CLEVELAND, M. D. • * Roberts BARTHollow, M. D. M A F P& T VVAIN'S - NIHEVV E O OIP3C IS NOVV READY FOR CA NVASSEPS. It contains over 600 pages of reading matter, with 250 engravings, designed crpressly for this work, by the best artists in the country. A gents now at work upon it are meeting with unparalleled success. Agents at Circleville, O., reports 25 orders in 2 days; one at Louisville, Ky., reports 175 orders in 8 days; one at Middletown, Conn., reports 200 orders in 12 days; one at Cincinnati, O., re. ports 250 in 12 days. Early applicants secure choice of territory. For circulars, terms, &c., address NETTLETON & CO., 161 Elan Street, Cincinnati, O. W. W. SEELY, M. D., - - - - - - Theasunes. & No. 118 West Seventh Street, Cincinnati. . C L U B R A T E S. 4 Copies to one address * * * * * * * * * * * $ 7.00 6 4 & 6& 10.00 12 & & & & 18.00 C O N T E N T S. W ºssºmsº Page The Clinic Lamp Bracket, by F. P. Anderson, M. D tº e º $ tº e º 'º º tº g g g º 'º º tº º tº $ 1 tº ſº tº $ tº I3 Rupture and Wounds of the stomach by J. Q. A. Hudson, M. D........14 LECTURE & Clinical, on Liver Cirrhosis by Prof. Duchek of Vienna, (From the Vienna Med. Press, Dec. 3, 1871.).............................................. 17 screNTIFIC Notes * Iron, the Coloring Matter of Nature—Extra-Uterine retation- The Development of Myopia........... ....................................... 19-20 MEE}}|{CALL NEWS The Liberal Professions—Medical Fees in Italy—A College for Si- beria—On Embalming—Suicide by Morphia Hypodermically— Death of Dubois--Oppolzer's Successor—Cholera—Strasburg School—Small-Pox—University of Warsaw—Jewish Medicine— Books and Pamphlets Received CHAINHCA L. NIEMIORAN HDA • * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * Yºrgotin, Hypodermically in Haemoptysis—Bromide of Iron—Suc- cessful Method of Treating Dysmemorrhea and Sterility—Com- pressed Air in Hooping Cough—The Diseases of Alaska............ 22-24 HOAIF; NEWS .................. a * * * * * * * g e • - - - - - - - - - - - - - - - - * * * * * * * * 24 The spring Course of 1872.......................................... 24 oRrginAr; Artirer:Es: - - - -, }; §ºn spesign:sº º Editor Dental Register J. & W. TAFT, TDTEINTTISTS 117 WEST FOURTH STREET, CHN CIN N ATI, O. wº a nº Begisters Now is the time to subscribe for THE CLINIC. The new volume is just commencing. With this number is forwarded the table of contents of volume first, hitherto delayed in press. A glance over it will reveal the fact that all the news, inventions and discoveries of the year have been duly and fully recorded. Can you afford to A Monthly Journal, CONTAINING 48 PAGES, Devoted to the Interests of the Dental Profession, be without THE CLINIC” cº, ITT, e- - 28 Carriage Manufacturer, NOS. 9 and 11 East Sixth Street, bet. Main & Sycamore. I MARE NOTHING BUT F/RS7 Czz SS. Wºo ºf A', , Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of LIGHT FAMILY CARRIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive variety of light elegant designs of different cost and finish. In vehicles especially adapted to - PHYSE&HANS” {jSE, The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. The superiority of my light gentlemen's buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price lists furnished on application. References to Dr. W. W. Dawson and all the leading Physicians in the city and neighborhood. CAMIA Rao MANUFACTURING COMPANY, MANUFACTURERS AND IMPORTERS OF AND Window Shades, 37 West Fovazz Sragaz, CINCINNXTI, O. UNI) ERWEAR GENTLEMEN. Handling much larger quantities of fine and valuable Underwear than any other firm in the West, we are enabled to purchase at closer fig- ures. We are therefore prepared to offer extra inducements to consumers. IHOSIEERY, FULL LINES OF THE BEST ALWAYS ON HAND. SHIRTS MADE TO ORDER. WILSON BROS, Pike's opera House, Cineinnati; 931 wabash Ave- *e, and 88 West Washington street, Chicago, | E. De ALIBRO & BRO. IMPORTERS AND MANUFACTURER8 OF FOREIGN and DOMESTIC WOODS In veneers, Boards and Plank, |frºnt-Maº','!-Biſſani ºil-Biiſi'i. The only house in the Western country that saws Spanish and Mexi- can Cedar for Cigar-Box Makers We import our own wood direct, and can sell at prices to compete with any and everybody. Also saw and keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. Office and Warerooms, 136 and 138 West Second Street, Veneer Mill, 507, 509, 511, 513 & 515 W. Sixth St., CINCINNATI, colò RF cºe co- Fashionable Hatters, IMPORTERS AND MANUFACTURERS OF #,ABERs' Fürs, 92 WEST FOTTERTEL ST. Opposite Post Office, CINCININ ATI. *Special Inducements to Medical Men. BASCOM & CARPENTER, Stationers, Printers -AND-> Blank Book Manufacturers, 13e VINE stre+SEr, &\\\\\\\\\\\\e Wm. Wilson McGrew, wo, ºr rasr rovara scºrer. PIKE's OPERA HOUSE BUILDING, In porter and Dealer . . —“I N.--— - Diamond and Gold Jewelry, Watches for Ladies and Gentlemen, . Sterling Silver Tableware, - Bronzes, Antique and Modern; Marble and Bronze Clocks, Marble Statuary, FAN cºr Coons, G E N E R A LLY. . O D O Fº I L E S S A. IN ID PA I, A. T A E L E • In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERs & BARTLETT, of Portland, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. . Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. - Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. - . - tº: In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Itachitic Affections, in Chronic Rheumalism, &c. - The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. - We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. F. E. SUIR F. E. S. WAYNE F. E. Suire & Co., WHOLESALE DRUGGESTs, IN/[ _AL INT TJ ET AL C T TJ TER, IT INT G- £Hemists AN ID f'HARMACEutists, CINCINNATI, OHIO, Have constantly on hand a full assortment of sye), EcºEYO YO33 UGS ANOO WXXºoxc)(N)es, cxxxenxxcAx. AxºeAx}A^egs, • TESTS, MEDICAL, GLASS WARE, &c., &o., And solicits the patronage of the trade and profession. We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and . Proximate Principles of Plants, Made in accordance with the U. S. P. and other recognized authori- ties. FINIHE AN ID FRAE HS CHIEMICALS, of the popular class of preparations known as H. T., TIX I FR, S, We manufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which . the nauseous taste of medicines are disguised, and they made pleasant to take. Bitter Wine of Iron, An excellent Chalybeate and tonic, Wine of Iron, &c AGENTS FOR BULLOCK & CRENSHAW'S Sugar-coated Pills and Granules. Price Lists of preparations and of Sugar-coated Pills sent by Mail upon application. The long standing and well and widely known repu- tation of our house we offer as a guarantee for the reliability of our preparation, and the quality of the goods sold by us generally. Tullû, º Instrument Makers and Practical Opticians, Beg leave to return thanks for the patronage extended to them through a long series of years (having been established since 1836), and in the reorganization of their firm will endeavor to merit a continuation of the same. We wish it understood by the Profession and the Public generally that our invariable rule is, to make or import none but the best in. Struments. Those in want of any of the acknowledged good aids of vision to imperfect eyes, will always find the best and largest stock of Lenses, Spectacles, and the best models procurable, with pains- taking skill to adjust them to all conditions of sight, at our house. Special attention paid to orders for Fine Microscopic Objects and Microscopic Apparatus, Magnifiers and Readers in great variety. Medicai Batteries, Barometers, Thermo- rºmeters, Hygrometers, Urinometers and Raian Gauges, of the most approved construction always on hand. All orders promptly and accurately filled. JAS. FOSTER, JR. dealing F. S. SHACKLETORD, : *** ** HAs. FostER, JR. & Co. S. W. Cor. Fifth & Race Sts., Cincinnati, 0. TXTR). S-INT-TMC-A-TER,SIEEI’S &P) TRUSSES. & No. 758 BROADWAY, NEw York I HAVE been in the habit of applying and recommending the Truss manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined. LIEWIS A. SAY RE, M. D. * - Surgeon, Bellevue Hospital. Parker to S. D. Townsend, M. D., Surgeon to the Massachusetts General Hospital, * BEG leave to state for the benefit of all concerned, that I have known Dr. S. N. Marsh the last fifteen years. * * I am in the constant habit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with any of the risks to the patient that exist in many of the plans suggested and attempted to be carried into execution. I have confidence in Dr. Marsh as a gentleman of honor and integrity, and as such recommend him to the members of the modi- cal profession generally. WILLARD PARIKER, MI. D. Professor of Surgery, New York City From Prof. Willard Dr. S. N. Marsh's Patent Radical Cure Truss, and all other kinds of Trusses, Shoulder Braces, Supporters, Elastic Stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Cure Truss Offices of S. N. MARSH & CO., No. 2 Wesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West l'ourth St., between Main and Walnut, Cincinnati. - OPPOSITE THE HIGH STEEPLE, JAN. 13, 1872.] T H E C H., H. N. H. C. L. A M P B R A C K E T - BY F. P. ANDERSON, M. D. Lecturer at the Good Samaritan Hospital, The ordinary stands for the attachment of larynggo- scopic apparatus have such limited movements, that we are compelled to have our patients in a variety of attitudes and in constrained positions before satisfactory relations can be established with the mirror. Moreover, they are utterly useless for the examination of other than the buccal and aural cavities. - Mr. W. H. Meredith, of this city, has designed and constructed for me an admirable contrivance for employ- ing the reflector whenever artificial light may be re- quired, To an upright stand, terminating in a globe, is at- tached a shaft made in the form of a clamp, each end of which is fitted with a socket; the lower one receiving the ball of the stand, the upper containing a ball at the extremity of a shorter shaft. This second shaft and bulb are made of three pieces, held together at the outer end by the collar of a clamp that steadies a vertical rod for the lamp; they are hollow, and passing through is a rod extending from the clamp of the lamp-supporter into the bulb, where the base of a cone-shaped head rests against a rubber ball, and the shoulder fits against corresponding inclines in the shaft. The rod to which the reflector is attached is swung by a ball and socket, and the vertical position main- THE CL.INI c. 13 tained by a weight below. When the long shaft or clamp is brought together with the hand screw, the rod in the second shaft is drawn back by the inclines pressing on the conical head, and the frame is held in any position desired. Thus, we have three universal joints under the control of one clamp. == #º *:::: *: - 4. Wº: tº: The Tobold reflector and mirror may be used not only for the usual purposes, but also for the ex- amination of the vagina, rectum, and with the endoscope attached as in the second cut, the urethra and bladder. As the light may be thrown at any angle, this ap- paratus would prove Servicable in operations neces- Sarily undertaken at night, and in surgery of the uterus. - - I prefer the light from good kerosine oil to Cincinnati gas, but the student lamps can be replaced by an Ar- gand burner easily. . —=º-e-ºº--— THE AGE OF PLANTS.—The following statement by M. Tandon exhibit the age to which certain plants may attain: Palm 200-300 years, Elm 355, Cypress 388 years, Chestnut 626 years, Cedars 800 years, Nut Trees 900 years, Linden 1076 years, Fir 1200 years, Oak 1400 years, Taxas 2880 years, the Mammoth of California(37 feet di- ameter, 450 feet high) 5000 years, Dracana Draco 7000 years. The Nestor of these trees was measured by Humboldt(74 ft. at the base)in 1799 on the island Ten- eriffe. As is well known it fell in the storm of Jan. 2, 1868. The Wellington trees may attain to the age of 3000 years and over. * 14 [JAN. 13, 1872. TIEEE IED CT I INTI C. RU PTURE AND WOUNDS OF THE STOMACH. BY J. Q. A. HUDSON, M. D. [Read before the Meigs and Mason Academy of Medicine, Dec. 21, ’71.] Continued from No. 1. CASE 1. A trooper attempting suicide shot himself with a pistol, the ball passing through from the epigas- trium, in front, and lodging in the loins, where it was extracted. Fluids passed from the stomach through the posterior opening. Symptoms of shock were slight. Vomiting is not mentioned as being present. The an- terior opening soon closed up, and in six weeks the man recovered (see Am. Journ. Med. Sci., Aug., 1830, p. 528). CASE 2. This is the case of Alexis St. Marton, so well known throughout the world. I will give the descrip- tion of the accident in the words of Joseph Lovell, M.D., who attended the case. “The charge, consisting of powder and duck shot, was received in his left side, at a distance of not more than a yard from the muzzle of the piece. It entered pos- teriorly and in an oblique direction forward and inward; carrying away the integuments and muscles to the size of a man's hand; fracturing and entirely blowing off the anterior half of the sixth rib; fracturing the fifth; lacerating the lower portion of the left lung and diaphragm and perforating the stomach. “I saw him in 25 or 30 minutes after the accident, and, on examination, found a portion of the lung as large as a turkey's egg protruding through the external wound, lacerated and burnt, and immediately below this another protrusion, which, on further inspection, proved to be the stomach, lacerated through all its coats, and pouring out the food he had taken at break- fast through an orifice large enough to admit my fore finger.” Without quoting the narrator further, all that it is necessary to add is, that, by appropriate treatment, and after a tedious separation of pieces of broken ribs and of cartilages and extensive sloughings of the soft parts, in one year from the date of the accident the man recovered with an external opening communicating with the stomach, which Dr. Lovell describes as follows:— “The perforation was about the size of a shilling, with its edges firmly attached to the pleura and intercostal muscles, and the food and drinks continually exuded unless prevented by plug, compress and bandage.” In this case there were no symptoms of shock, no nausea or vomiting, and no blood passed out of the ori- fice in the stomach. A few months subsequent to his recovery a valve gradually formed by protrusion of the coats of the stom ach, that prevented the egress of the contents, but which ç »uld easily be pushed inwards (see Am. Med. Recorder, Jan., 1825, p. 14 and Beaumont's Eageriments, 1833, p. 17). CASE 3. By Benjamin Travers. A woman aged 53, in a fit of despondency, attempted suicide after the Chinese style. Wound transverse, below the umbilicus, three inches long. Part of large curvature of the stom- ach, the arch of the colon, and the entire large omentum protruded and strangulated in the wound. Omentum was found partially detached from the stomach, and on the stomach a peritoneal graze half an inch in length, and at another point a perforation of all the coats, ad- mitting the head of a large probe. Pulse 102 and irreg- ular, very faint and exhausted, disposition to hiccough. The perforation in the stomach was encircled by a fine silk ligature, the ends cut off close, and all the parts returned into the abdomen. The external wound was closed with the quill suture. Antiphlogistic treatment pursued as needed and the woman was well in two months (see Med. Chir. Review, April, 1826, p. 547). CASE 4. The following case exibits a parade of ig- norant rashness on the part of the surgeon, and the pow- er of nature over his misguided practice, aſid the acci- dent, that seemed combined to thrwart her efforts. The patient was an Indiah. The surgeon was called six days after the Indian was stabbed; during which time the Indian had walked thirty miles. “There was a wound four inches long, a little below and to the left of the Scrobiculus cordis. Protruding from the wound there presented a tumor, which, upon first view, I thought to be a portion of the bowels, but upon further inspection, I discovered that it was most probably omentum.” As there was some evidence of sphacelus a ligature was ap- plied to the whole of the protruded mass. This brought on incessant vomiting, small rapid pulse, cold and clammy skin, indicating the necessity of removing the ligature. These symptoms should have intimated cau- tion on the part of the surgeon, but timidity and caution were not his forte. Since the ligature would not succeed, he imagined that the knife would. He says, “I carefully separated the already dead parts of the tumor from that which was not in a state of gangrene. In doing so, I had to remove a portion of the stomach. The stomach was secured by ligature, and confined within the lips of the external wound. The wound was stitched and dressed with adhesion plaster.” Symptoms of shock followed, from which he rallied, and in twenty-two days the Indian was well, there being a “firm adhesion of the stomach along the lips of the external wound” (see Am. Journ. of Med. Sci., May, 1839, p. 261). CASE 5. A negro escaping from servitude, gave a back lick with a large knife while running and struck his pursuer, wounding him in the stomach. “The wound was about two inches below the ensiform cartilage and nearly three inches long externally. The stomach was opened by a wound more than two inches long. The dinner which the man had just taken before the accident' consisting of bacon, cabbage and cider, was partly dis- charged through the cut, and part of it escaped into the iº- JAN. 13, 1872.] T TH. H. cf.INTI c. 15 peritoneal cavity.” The external wound was sown up by an old Soldier, but the stitches were removed by the physician (Dr. Archer) on his first visit, two days after the accident. An abscess in right groin was opened during the subsequent treatment which discharged cabbage, etc. No statement given in regard to symp- toms of shock nor as to haematemisis. The man recover- ed, time required not given (see Am. Journ. Med. Sci., Oct., 1844, p. 327). - CASE 6. A Prussian peasant, endeavored to excite vomiting by pushing a knife down his throat, which he accidentally swallowed. . The account does not say whether the knife was open or shut. The knife was afterwards removed by Daniel Schroaben, by an incision to the left of the epigastrum. External opening two inches in length, dimensions of the wound in the stom- ach not stated, but it was probably small. The knife extracted was found to be nearly two inches long. No sutures were made in the stomach. The internal wound was closed by five pig sutures. “No serious symptoms ensued, and the patient soon got well” (see Am. Journ. of Med. Sci., Oct., 1844, p. 330). - CASE 7. A Prussian woman, swallowed a knife seven inches long which she was using to excite vomiting. Eleven days afterwards the knife was removed by gar- trotomy by a Dr. Hubner. “He found that the blade had already pierced through the stomach and had ex- cited slight suppuration around it.” No serious symp- toms are mentioned as having occurred, and no mention is made of sutures. “Her recovery was prompt” (see Am. Journ, of Med. Sci., Oct., 1844, pp. 330, 331). CASE 8. “A young fellow of Sprague, out of mere sport,” says Crollius, “swallowed a knife nine inches long, the point of which presented a little above the fundus of the stomach towards the left side, and the handle towards the spine. Two months afterwards it was successfully extracted from the stomach by Florian Mathis, first surgeon to the emperor.” No mention i made of any bad symptoms occurring; of shock or hem- orrhage, nor is any mention made of the use of sutures. (see Am. Journ. of Med. Sci., Oct., 1844, p. 330). CASE 9. A negro boy, six years of age, fell on a pair of sharp shears making a flap-like wound in the integu- ment near the left hypochondrium, through which the stomach protruded, exhibiting a wound in it three-fourths of an inch in length, which was discharging the contents of the stomach. The stomach was treated at the wounded part with a single stitch of fine silk. “The wound of the stomach was brought exactly opposite the integumentary wound and gently retained within its verge. A single stitch, patent lint with cold water and a bandage completed the dressing.” The only bad symptom mentioned is nausea and vom- iting while handling and returning the protruded stom- ach. Haematemesis is not mentioned. The boy recov- ered; time not stated (see Am. Journ, of Med. Sci., Jan., 1852, p. 285). * A case of wound of the stomach with recovery is re- haematermisis. attended to, that he felt well. ported in Am. Journ. of Med. Sci. for July, 1855, p. 273, but the symptoms detailed do not satisfy my mind that the stomach was wounded, consequently I shall not quote it. - CASE 10. G. H. Bowers, Private, 8th Ills. Cavalry wounded near Frederic, M. D., Sept. 13, 1862, “by a musket ball, which entered two inches above the um- bilicus, an inch to the left of the lienea alba, and made its exit beneath the tenth rib, three inches to the left of the spinous process of the tenth dorsal vertebraf. Im- mediately after he was shot he vomited blood copiously until syncope supervened. Haematemisis recurred fre- quently for seven days, and blood passed at stool. Acute peritonitis ensued. Liquid taken into the stomach passed freely through the anterior wound.” In eight months the parts were restored to their natural function, but the body was bent forward by intra-abdominal ad- hesions (Circular No. 6 S. G. O., Nov. 1, 1865, p. 25). CASE 11. Giovanni Nieto was wounded with a knife in the epigastrum accidentally. The wound was a little over an inch in extent in the parietes of the abdomen, being a little to the right of the linea alba between the umbilicus and ensiform cartilage; through which had passed a portion of a meal he had partaken of about two hours before the accident. A portion of the omentum of about four fingers breadth protruded. The omentum having been cleansed and returned, the parietal wound was closed by the twisted suture, over which a compress was applied. There were no symptoms of shock and no “He declared after his wound had been On the fifty-fifth day Nieto was completely well” (see Am. Journ. of Med. Sci. July, 1871, p. 272). CASE 12. The following statement of this case is all that I have access to relating to it. It is from Ham- ilton’s Mil. Surg., 1865, p. 361. Hamilton refers to the Am. Med. Times, April 4, 1863, for a full account of it. Hamilton says, “Dr. Peters relates in the same paper a case of punctured wound of the stomach, which came under his notice in New Mexico; the wound having been inflicted with a cheese knife. In this case, the man recovered in a short time without surgical inter- ference.” In this list of cases we have three of gunshot wounds and nine of wounds by cutting instruments, of which, in three cases the wound in the stomach was made by the surgeon for the extraction of foreign bodies. No sutures to the stomach were used in the gunshot wounds. Of the nine cases of wounds by cutting instruments sutures are stated to have been used in three cases. In one case of cxtraction of foreign body it is stated that no suture was used for the gastric wound. No mention is made of suture to the stomach in the other two cases of extraction of foreign bodies, and it is probable that none were used. In three cases of, incised wounds sutures were used. In one a single stitch; in another a small perforation was enclosed by a ligature; and in the third a ligature applied to the opening made by carelessly &: 16 [JAN. 18, 1872. TIEEE CI.INI c. cutting a part of the stomach away when removing gangrenous omentum. As regards the use of sutures applied to incised wounds of the stomach, there is little doubt of their necessity and usefulness in certain cases. We have, however, but very little instruction in our text books upon this point; indeed many of them make no mention of incised stomach wounds whatever. - Hamilton, in his Military Surgery 2865, makes no reference to incised wounds or their treatment, except by inference in his remarks on the case already quoted. Erichsen, in the last edition of his Surgery, does not refer to incised wounds of the stomach. The following writers are wholly silent on this subject: S. Cooper, The Prac. of Surg., 1846; B. Cooper, First Lines, 1885; John Hunter, Principles of Surg., Am. Ed., 1839; Malgaigne, Oper. Surg., Am. Ed. 1851; Wm. Ferguson, Prac. Surg., 1853. There is no allusion to either rup- ture or wounds of the stomach, in Braithwaite from the commencement to the present time. Dorsey, in his Elements of Surgery, V. I. p. 104, says, “When a wound can be seen, a number of Stitches proportioned to its extent must be used, the ligature cut off close, and the parts returned.” Collis says, (Lectures on Surgery, Am. Ed., 1845, p. 133,) “All you can do is, in wounds of the stomach, to keep the patient on the smallest quantity possible of food; and make him observe the utmost quiet.” Gross, (System of Surgery, 2nd Ed., v. II. p. 597,) says, “Wounds of the stomach must be closed by suture, and afterwards managed with especial reference to the prevention of undue inflammation.” A little further on he says, “Where gastroraphy has been neglected, or rendered impracticable, etc., but he does not give the conditions which render it imprac- ticable. In the Medico Chirurgical—Review, July, 1847, is a review of G. J. Guthrie's work “On Wounds and In- juries of the Abdomen and Pelvis.” On page 90 the reviewer gives in his own (the reviewer's) words Mr. G.'s method of treating wounds of the stomach. “If the wound is small, it must be treated by the continuous suture, first that of the intestines; and if the external aperture through which its contents are effused is too small to admit of the wound in the organ being sewn up, it should be enlarged. This is, however, only a suggestion for the prevention of certain death; Mr. Guthrie never having put it into force yet” Druitt, (Surgery, 1860, p. 463) mentions only the treatment of wounds of the stomach in connection with protrusion, and directs that the wound be sewn up and the parts returned. These meagre statements by surgeons who make any reference to the treatment of wounds of the stomach, and the silence of the majority of writers, are but the necessary result of want of experience and observation by reason of the great fatality of these accidents. y Death supervenes too rapidly to apply any treat- ment. The following rules in regard to the treatment sº of incised wounds of the stomach, are offered as probably a fair representation of the treatment according to the barren authority we can find. 1st. When the wounded part is protruded, or if it is easily accessible through the parietal wound, it should be treated with suture according to its extent. For a puncture or a perforating wound, its simple inclosure with a small ligature on the external surface is all that is required, if it is thought necessary to apply any suture. These small wounds (if 3 of an inch or less) will probably do well without suture or ligature if the stomach is and be kept empty. If the cut is of larger extent, the interrupted suture, or Gelys suture, or Lemberts suture, is probably preferable to the continued Suture. If it is known that the stomach is full, or partially so, more care should be used to secure an even coaptation of the edges of the wound, and the stitches should be nearer each other, not more than 1-6 of an inch apart. Some surgeons in wounds of great extent are partial to the continued suture as it is supposed to secure a more perfect adaptation of the parts, and is more easily applied. The kind of suture employed, is, perhaps not so import- ant as the skillful application of it, Securing a nice coaptation of the serous surfaces. 2nd. After the application of the suture, if practicable, the stomach wound should be kept within the lips of the parietal wound, or near to it since if effusion occurs there may be opportunity for external egress, and since the inflammatory action in the parts favor adhesion and consequent prevention of effusion. 3rd. The wound in a protruded stomach might be in such a part of it that apposition of the parietal wound with the former could not be maintained after a return of the parts. In such cases the surgeon is com- pelled after sewing up the wound to return the protru- sion and trust to nature. 4th. When we apprehend from the attending symp- toms that the stomach is wounded, but from the small- ness of the wound, we cannot apply the suture, and if there be no evidences of effusion into the peritoneal cavity, the case is to be treated by other means to be given further on, and no attempt is to be made by enlarg- ing the external wound to Secure by suture the wound in the stomach. • 5th. In all cases where the stomach wound cannot be reached and no effusion eacists, the external wound should be closed by suture and adhesive strips, compresses and bandages applied to aid in Securing as far may be an immobility of the parts. 6th. In cases where there is an effusion in the neigh- borhood of the wound the external wound if it has been closed should be opened, and by position and moderate compression an attempt be made to cause an escape externally of the foreign matters. Should this fail, the external opening should be enlarged, and the matters allowed to escape, and if after enlarging the external wound and allowing the escape of the effusion the stom- JAN, 18, 1872.] ach wound can be reached, it should be secured by Suture. 7th. What is to be done in cases of effusion into the gen- eral peritoneal cavity? These cases must be rare, since with the stomach wound and the effusion, death will usually soon follow ; but that such cases may occur and recover, case 5 treated by Dr. Archer proves. Many, probably most surgeons would abandon these cases to nature and to certain death ; yet would it not be preferable for the surgeon to follow G. J. Guthrie's plan before referred to, viz., to enlarge the external wound and secure if possible the wound in the stomach by suture, and then aid in the removal of the effusion by injecting a weak, tepid solution of chloride of sodium into the peritoneal cavity, as was successfully done by Peaslee in a case of double ovariotomy? (See Am. Journ. of Med. Sci., July, 1864, p. 48.) It is undoubtedly true that there is a difference in this membrane (the peritoneum) in different individuals as to its sensitiveness to morbid impressions, from the con- tact of foreign bodies; and when the system does not yield rapidly to the malign influences of the effusion it would appear proper that the surgeon should aid nature by removing the existing effusion and prevent its con- tinuance by securing the wound in the stomach. This plan of treatment is merely presented as a plausible one and seems to the writer to be the only reasonable course to pursue. t It may be urged against this plan that the evidences of effusion into the peritoneal cavity are sometimes un- certain. True, yet in cases when the Surgeon can make a positive diagnosis, must he abandon the only probable means of hope 2 The general treatment of wounds of the stomach may be stated in brief, to be ; absolute rest of body, in a posi- tion to fully relax the abdominal muscles, absolute ab- stinence from food for several days; using nutritive in- jections if withholding food by the stomach is long re- quired, as was done in the case of H. Martin. The use of ice or ice-cold applications to the parietal wound, the very limited allowance of ice or ice water to allay thirst. Opium to allay pain and inflammation, con- joined with liberal, general, and especially local blood- letting as circumstances demand. Enemas may be used to secure alvine evacuations if necessary. When food is resumed by the mouth, it should be given in a com- Centrated liquid form, and in Small quantities, such as beef essence, milk, etc., etc. —sº-o-º-- TIT FOR TAT—The following between General Syester and Dr. Warren from the Wharton trial now in progress at Annapolis; While this subject was under discussion, Attorney Seneral Syester remarked to witness: “A doctor ought to be able to give an opinion of a disease withont making mistakes!” Witness—They are as capable as lawyers. Attorney General—Doctor's mistakes are buried six feet inder ground. A lawyer's are not. Witness—But they are sometimes hung on a tree. T IEC IH C T , IIST I C - 17 IL H W E R C H R R H 49 S H S . A CIinical Łecture by Prof.; Duichek, Vienna. [From the Wiener Med. Presse, Dec. 3, 1871.] We learn from his history that our patient has been in the habit of imbibing freely of beer. For some time he has been ill, or better said perhaps, has felt that he has become weak and feebler. For the past six or seven weeks there has been vomiting every morning after coughing and retching in the throat, vomiting besides of mucus, of a fluid of sour taste. Associate with this anorexia occurred and gastric symptoms of other nature, and then SWelling of the lower abdomen, swelling which is significant, and which shall closer en- gage us. The first glance at our patient teaches us that we have to deal with a malady which extends its im- press over the whole body, and that we shall find changes in the abdomen which have exercised a slowly ad- vancing influence upon nutrition and the general health. Our patient shows marked bony development but the subcutaneous tissue is poor in fat, the skin is lax, flabby and paler than matural; the back of the hand is very pale; only on the uncovered surfaces is the healthy tinge apparent. There is no oadema of the lower ex- tremities. He can walk, there are no cephalic symp- toms. His tongue is somewhat, yet not markedly, coated white; neck and chest show the usual relations. The left nipple is somewhat higher than the right, an evidence that the right chest is narrower than the left. The thoracic arch is rather prominent. This may not be regarded, however, as the result of the abdominal swelling, for the abdomen is soft and yielding, and in no case does enlargement or dilatation of the lower thorax occur from this cause. Respiration is easy, symmetrical. Easy it is to see, however, that respiration is not the same as in a healthy man. In health there is a marked elevation of the anterior abdominal wall during in- spiration, a consequence of the descent of the diaphragm —the upper portion of the chest remaining comparatively quiet. In the female sex the diaphragm is less active, its descent is not so marked, on the other hand, there is greater motion of the upper ribs; plainer this becomes in disease. Just such a manifestation is pres- ent in our case, for a simple mechanical reason. In all diseases which distend the lower abdomen, marked ascites, meteorism, etc., the descensus diaphragmatis is hemmed; it cannot sink to its usual position without overcomingstronghindrances, and in such cases vicarious costal respiration is observed: in man it signifies mechan- ical obstruction to diaphragmatic descent. Such an obstruction is present in the case before you. Our pa- tient breathes more with his upper ribs because the descent of the diaphragm is hindered. When ascites is " | marked, any descent of the diaphargm ean scarcely be 18 [JAN. 13, 1872. __ TIEEE THE C T , T N T C - * demonstrated, percussion sounds are full as high as the fourth rib. The fifth intercostal space resounds with the tympanites of the stomach. Heart dullness reaches to the sixth rib, a little lower perhaps than noamal. Externally, cardiac dullness extends to its normal bounds, internally, up to the sternum is perfectly clear sound, distinct dullness at the left sternal border. The relations of cardiac dullness, therefore, are almost normal. To the right, mammary line, fifth rib, but light dullness is perceptible; above the sound is clear. Dullness, thus, is higher on the right than usual. Plainly this dullness depends upon the liver. At the xyphoid pro- cess there is dullness corresponding to the thickness of the left lobe of...the liver. When this is voluminous, even though the stomach be distended, the sound is still dull, when thinner, the dullness is less marked. Further to the left the sound of the stomach is manifest, perfectly clearly the dullness and clarity separate. The hepatic dullness may not be traced further to the left on account of the gastric sound, plainly because the liver lobe has increased in thickness. The lower border of the liver has its usual place, but its upper border is higher because of the higher diaphragm. Palpation in the hepatic region teaches us nothing concerning the liver; this region is empty, offering but little resistance, such as intestinal convolutions might yield. Towards or at the close of the recti muscles this resistance in- creases, so that we can say that the liver has not essen- tially increased in volume. It lies a little higher and we might conclude because it is a centimeter or two higher that it is somewhat larger but not much weight may be placed upon so little difference. If we examine the second important organ of the ab- domen, the spleen, we find the sound clear to the sev- enth rib, dull from the seventh to the tenth. Anteriorly it reaches in its broad diameter sharp up to the border of the ribs. Palpable is it not. This is, perhaps, because the tension of the abdominal parietes is very great so that the finger can only sink to a centimeter's depth. We demonstrate thus, in addition to the described condition of the liver, a marked enlargement of the spleen. Now, then, our first question is whence and since when is this enlargement? Tumor from intermittent ſever is not his history. This is, truly, its most frequent cause of which we shall speak anon. There is anothſ r cause of splenic enlargement; it is the presence of amyloid degeneration with like disease of the liver and kidneys, a sequel often enough, of precedent syphilis. So often, indeed, that it was formerly believed that amyloid degeneration only occurred in the case of syphilis, a view which is by no means correct. It may be present, this degeneration, probably in consequence of the destruction of the elements of the organ in other diverse conditions, may occur in intermittent fever. After a protracted intermittent, a permanent spleen tumor remains: amyloid degeneration then often affects it; presenting itself, thus, as a residium of the disease. We discover in our patient a demarcation line in the linea alba between the clear and dull sound. To the right and left the dull sound is limited by a horizontal line. We change the position of the patient, still we have the lowest part dull, distinctly marked again from tympanites above by a horizontal line. The parts now highest, before dull, yield now the clear sound. The Sounds have been changed thms with the change of the patient's posture, showing a free fluid in the abdominal cavity. It has sought the deepest part of the cavity and is separate from the tympanites of the swimming intestines above by a horizontal surface. A small quan- tity of fluid in the abdominal cavity sinks into the pel- Wis and is only demonstrable when it has risen above the pelvic intestines and is manifest to percussion. To resume, then, we have before us a condition im- plying a chronic disease. We observe general emacia- tion and debility. We have seen that the liver is a little though not markedly higher than normal; below it maintains the usual position. There is therefore slight enlargement rather than slight diminution in its size. The left lobe extends less far to the left than usual; its limiting border is detectible at the linea alba So that we must consider the left lobe to be rather thin- ner than normal. . Further we found the spleen enlarged, and finally free fluid is present in the abdominal cavity. From these tracings we have to decipher the disease before us. Because we have found so little wrong with the liver we may not depart from this organ in our dis- cussion for I shall exhibit to you later that we are able to draw definite conclusions as to the constitution of the liver from this complexity of symptons present. To this end we must refer to other manifestations, the most striking of which is the free fluid in the abdominal cavity. Det us inquire, now, how may such an accu- mulation, in general, occur 2 That the fluid here is not encysted, the change of position proves. This must first be clear because there are various kinds of free fluids in the abdominal cavity. An encysted tumor with considerable dullness would notºfurnish to per- cussion a level surface. This is of greatestimportance in the diagnosis of female abdominal disease because with them diseases of the sexual organs, ovarian cysts, uterine tumors, are so frequent. All tumors of considerable size may be distinguished from free fluids in the major- ity of cases by the fact that their limiting borders show to percussion a convex line. Tumors, too, as you may well undsrstand, are not so freely movable. There is one disease, however, whose differential diagnosis in this regard will give you trouble. It is chronic peritonitis. This is usually associate with neoplasms, tubercle, etc., and there is not only fluid effusion present, but also new formations, false membranes occasioning adhesions be- tween the intestines, abdominal walls and other organs. Flnids of this origin do not change place in the same m.anner on rapid change of position of patient. It flows between the adherent intestines and even this change occurs slowly and imperfectly, correspondingly mystify- JAN. 18, 1872.] T H E c T, TTNTI c. 19 ing the sonnds of percussion. If, then, the fluid may not he moved in toto, the supposition that pathological adhesions are present is justifiable. Of course this alone would not determine the disease, but it would establish the fact of adhesions and previous and concurrent in- flammatory lesions and then the question would arise what is the nature of the inflammatory process. The present case precludes such an iuſlammation: we have here to deal with a hydrops formed in the serous cavity; the tissues concerned having been changed only in the lightest degree—our case is hydrops ascites. Every hydrops naturally implies a stasis in the veins concerned or in the lymph vessels. Our first suspicion would point to venous stasis, and in this region as no other venous system could produce such a lesion, to the vena portae. We believe, then, that the circulation in this system is hemmed, either its trunk or in its branches in the liver, Always when ascites alone is present our first suspicion is directed to this vessel. Before going further we should mention that just such an ascites in connection with oedema of the feet may occur in Brights disease, with pulmonary oedema in bronchial catarrh and in heart disease. The question then arises is this ascites but a partial manifest of a general dropsy, is there, in other words, some disease present which may be regarded as the cause of general dropsy. In our case the present condition precludes such an idea. There is no trace of hydrops in the lower extremities. Possibly oedema was there and has since disappeared. Patients not infrequently present with the statement that they were dropsical in the feet but it has since vanished and is now confined simply to the abdomen. In such cases such changes have been effected in the peritoneum, per- manent thickening perhaps, as to have interferred with its reabsorption of the fluid effused. Here an ac- curate history is the great desideratum. In our case it is definitely determined that Oºdema of the extremities never “did exist. There has been at no time, then, a lesion causative of general dropsy. Heart diseases, kidney diseases, thus, are excluded. - [To be continued.] —º-e—cº- SCIENTIFIC NOTES. IRON, THE COLORING MATTER OF NATURE.-And last of all: A nobler color than all these—the noblest color ever seen on this earth—one which belongs to a strength greater than that of the Egyptian granite, and to a beauty greater than that of the sun set or the rose —is still mysteriously connected with the presence of this dark iron. I believe it is not ascertained on what the crimson of the blood actually depends; but the color is connected, of course, with its vitality, and that Vitality with the existence of iron as one of its substan- tial elements. & Is it not strange to find this stern and strong metal mingled so delicately in our human life that we cannot - evº, º Without its help?—Ruskin—The Two Paths EXTRA-UTERINE FOETATION.—A case of extra-uterine foetation was reciently admitted into the Vienna Hos- pital. "When the patient was dying, it was determined to make an effort to save the child. The Caesarean op- eration was performed, and the child gasped once or twice, but did not show further signs of life. The child was found quite free in the peritoneal cavity” and the post-mortem examination revealed the fact that the im- pregnated ovum had dropped into the fold of Douglas, and attached itself to the peritonéum. The umbilical cord was found surrounding the uterus in several coils, while it is supposed that the child escaped from the membranes two or three months ago. The Fallopian tube was so much spread out as to be undistinguishable as to its distal termination. The parts will be subjected to a careful examination, in order to see how far the pla- centa became formed, and the vascular supply acquired from parts not originally destined for the purpose. As evidencing the innate power of its support and growth in the impregnated ovum, without the aid of the organ specially furnished for its reception and growth, the case is one of no ordinary interest. EIN BEITRAG Zur Entwickelungs-Geschichte der Myopie, gestützt auf die Untersuchung der Augen von 4358 Schülern u. Schülerinnen. A contribution to the development of Myopia, based on the examination of the eyes of 4,358 Scholars, girls and boys. We extract simply some of the prominent points from this interesting article (to be found in Graefe's Archiv., vol. xvii, part i). The pupils were in seven Russian gymnasia where the ages ranged from 10 to 21; One progymnasium, four German Schools, for boys and girls, with ages from 8 to 20, and a normal School for educating teachers with ages from 17 to 24. Myopes - - - tº- 1,317=30.2 per ct. Frnmetropes - - º - 1,132=26. ( & Hypermetropes - º * - 1,889-–43.3 “ Amblyopes - - -> --> 20= 0.5 “ Total - - 4,358 100 per ct. Among 3,266 boys, there were Myopes tº t- º º 1,017=31.1 per ct. Emmetropes - - º - 867–26.5 “ Hypermetropes - - - 1,360=42. { { Amblyopes - - tº- tº- 13= 0.4 “ *=s* Total - s 3,266 100 per ct. Among 1,092 girls, there were Myopes gº * - º 300=27.5 per ct. Emmetropes - - * - 265 – 24.2 “ Hypermetropes - º * 520–47.7 “ Amblyopes - - - - = 0.6 “ Total - - 1,092 100 per ct. 20 [JAN. 13, 1872. T TE-ITE] . CT I I INT I C - Among 2,534 pupils of the Russian Gymnasia there Were Myopes - - - - 866=842 per ct Emmetropes - * * * - 654=25.8 “ Hypermetropes - - - 1,003=39.5 “ Amblyopes - - - - , 11= 0.5 “ Total - . 2,534 100 per ct. And among 1,824 pupils of the German Schools there Were * Myopes - - - - 451=24.7 per ct. Emmetropes - * gº - 478–26.2 “ Hypermetropes - - - 886=48.6 “ Amblyopes - * tºp * > 9– 0.5 “ Total - - 1,824 100 per ct. The large per centage of hypermetropes will be ob- served, and the author concludes that between the ages of 6–7, still more hypermetropes will be found. In the lower classes he found two-thirds of the children with H.; in the upper, one-third. Hence, he regards the normal refraction of young uninjured eyes hyperme- tropes. The so-called emmetropia or even myopia be- ing an exceptional condition for this eye. - In regard to the use of concave glasses, he says, their use while the refraction is undergoing changes, has of itself an injurious effect upon such eyes and he regards it a misfortune to be obliged to prescribe them for young myopes. He is inclined to modify the opinion usually So strongly expressed, that a highly myopic eye is a dis- eased eye. Undoubtedly, as he states, many highly myopic patients with excellent vision are never seen by the ophthalmologist; only those presenting subjective disturbances. He claims that the increase of myopes in the classes of more years study show that it is the occu- pation with all its attendant circumstances, that pro- duces this condition. - Myopia occurring in an hypermetropic or emmetropic eyeball, is due to the lengthening of its axis, and the author feels sure that the chief cause lies in the badly constructed school desks, and insufficient and bad light. ––– mºs-o-º- MIMEDICAH, NEWS. THE LIBERAL PROFESSIONS.—While I allow, that peculiar and important advantages arise from the ap- propriate studies of the three liberal professions, I must confess, that in crudition and Science, and in habits of deep and comprehensive thinking, the pre-eminence, in some degree, must be assignod to physicians.—Parr. MEDICAL FEES IN ITALY.—The question whether it was advisable to have a fixed tariff of medical fees, either general or local, was discussed at the recent meet- ing of the Italian Medical Association. The decision was, by a not very remarkable majority, in the negative in both cases. A COLLEGE FOR SIBERIA.—A quarter of a million dollars has been placed in the hands of Minister Tolstoi to form a University in Siberia. ON EMBALMING-The art of embalming, as is well known, is very old; even the ancient Egyptians had introduced the practice from Ethiopia, a country abounding in various gums, which served them to pre- serve the remains of their relatives. The transparency of these substances had induced some travelers to assert that the bobies were embalmed in glass, like insects in amber. posed the absurdity of such a report, since it is more than probable that glass was Scarcely, if at all, known amongst them. wax, and the Scythians Sewed them up in skins. De Pau and many other writers have ex- The Persians enveloped their dead in The operators were the priests, who persuaded the multitude that the immortal part of our being was re- tained within its earthly house so long as the corporal form could be preserved entire, and a belief in the transmigration of souls naturally led to the desire of re- taining them as long as it was possible in their former bodies; and the words of Virgil—“animamque sepul- chro, condimus”—would seem to warrant this belief amongst the ancients. The operator, or “incisor,” as he was called, appears to have been considerered a degraded being; for Diodorous tells us that, after the operation, he was pur- sued by the relations of the defunct, and pelted with stones, as having polluted the remains of the dead. As to remunoration, Diodorus Siculus states that the first class embalming cost a silver talent, the second twenty minae, and the third scarely anything. Rymer’s “Foedera,” vol. i. p. 1001, will be found a letter from the Keeper of the King's Wardrobe to Sir Ralph de Stoke, Clerk of the Great Wardrobe, stating that Richard de Montpelier is going to London on account of the king's (Edward I.) illness, and desires that every In facility may be afforded him to procure and make up the medicines. “Propter Infirmitatem Domini Regis per ordinationum Magister Nicolaus de Tyawick” (sic). Richard de Montpelier's account for this illness and subsequently the embalming the king amounted to £134 16s. 4d., a considerable sum in those days. Amongst other curious items we find:— £. S. d. Pro Emplastris Cironeis - - - - 4 0 0 Item pro Terebintine destillato - - - 0 40 0 Item pro uno Emplastro pro Collo Regis cum Ladano et Ambras Orientalis - - 0 60 0 Item pro vi. Malis Granates - - - - 0 60 0 Item pro sex unciis de Balsamo ad Corpus Domini Regis unguendes - gº - 13 0 0 Item pro pulveri aromatice de Aloeis Thuris Myrrhae ad ponendem in Corpord Regis 4 0 0 Item pro Musco uncia iiij. ad Ponendem in - Membris Regis (a) - - ſº - 0 60 o A curious fact with relation to the embalming of . JAN. ,131872.] TIEEE THE CIT I I INTI C. 21 Edward I. will prove that Master Nicolas of Tynwycke (who, the king said “was, more learned and fit to have the care of his health than any one in the realm”), Master Peter, the Surgeon, and Richard of Montpelier, the Espicer (or apothecary), did their duty well, for about fifty years ago the tomb of Edward I. was opened and the body found entire. A zealous antiquarian, Sir J. Ayscough, was induced to taste the “pickle” or fluid in which the royal body was preserved, and even then, more than 500 years after the embalmment, it showed traces of the spices used, and of which we have just given the charges and accounts. In modern times we find that Edmond Phillips had £40 4s. 8d. for embalming the body of Thomas Sutton, the benevolent founder of the Charterhouse. In the case of George II, the two Sergeant-Surgeons had £1228s. 9d. each for “opening and embalming,” and the apoth- ecary £152 for “a fine double cerecloth and a due quantity of rich perfumed powders.”—Times and Gaz., Dec. 9, 271. SUICIDE BY MORPHIA HYPODERMICALLY.--Dr. Stan- ton of Pensylvania met his death by an overdose of Morphia, one grain, self administrated on himself for the relief of an erysipeloid inflamation following a post- mortem. “Every remedy and appliance known to sci- ence were promptly used for his relief but without avail.” “Thus perished one of the brightëst ornaments of the Medical profession—a victim to his professional devo- tion and to the remedy he had so often successfully used to relieve the suffering of his fellow-men.”—Ea- change. DEATH OF DUBOIS-M. Paul Dnbois, Prof. of Mid- wifery in Paris and one of the most eminent obstetric authorities in France died on Nov. 29, at the advanced age of 76. He had held his professorship for 25 years. OPPOLZER's SUCCESSOR-Prof. Bamberger is finally ap- pointed by the new minister of Austria to fill Oppolzers place. Further intrigues are over. The home talent party is defeated and dead. There is general jubilee. CHOLERA-This pestilence has never persisted with Such obstinacy. Last month 379 fell victims in Con- stantinople in a single week. In Austria and Galicia it prevails still in all the old places of attack. In thir- teen places from which reports have been received 179 persons have been attacked; of these 154 died. STRASBOURG—The medical faculty is reorganized. Sixty students are already enrolled. SMALL-Pox—Our epidemic is slowly abating. Deaths average but five to six daily. As usual towards the close of every epidemic the type of the disease is consid- erably modified. Cases of confluent small-pox are rari- ties. - -: - THE UNIVERSITY OF WARSAw.—The Russification of the Warsaw University is now complete. All the Polish Professors have been removed. JEWISH MEDICINE.—We have observed in a religious contemporary devoted to the conversion of the Jewish race (the Scattered Nation), Sóme papers by one of our fraternity, Mr. Gaskoin, on “Medicine as Practiced by the Jews.” The September number contains an article under the heading “The Foundation of the University of Coadova,” which has an original stamp, and which sets things in a new and as yet unconsidered light. We hope to see these papers continued. From the Decem- ber number of the same publication, we are ſain to bor- row a few “Talmudic Gleanings.” These passages are of an extremely biting character, and serve to show the priestly race of yore in strong antagonism to our art: a “Talmudic Gleanings. “14. A Doctor that heals for nothing, his cure is worth nothing—Bava Kama, fol. 85, i. “15. Most donkey drivers are wicked, most camel drivers are worthy, most sailors are pious, but the best of Doctors are for hell.—Kidushin, fol. 82, i.—Note.— A Doctor, says a certain writer, has the advantage over the Angel of Death. The latter kills gratis, but the former is paid for it. - “16. Seven have no portion in the world to come—the legal writer, the scribe, the best of Doctors, etc.—Avoth. Drö. Nathan, c. 36. e “17. When a patient says, I am in need of (certain food), and the Doctor says he is not in need of it, the patient is rather to be listened to ; for(Prov. xiv., 10). the heart knoweth its own bitterness.-Yoma, fol. 83, c. 1. “18. If there be no Israelitish Doctor in the city, but there are in it a Samaritan Doctor and a Gentile Doctor, the latter may circumcise (a Jewish child), but not the former.—Avodah Zarah, fol. 26, c. 2. “19. Physician, heal thy lameness.—fol. 23, c. 2.-- Times and Gaz. Dec. 16 '71. We commend unto these theological Savages the fol- lowing: “The skill of the physician shall lift up his head; and in the sight of great men he shall be in admiration.”— Eccles. awarvi. 3. ——º-e—º--- Boolºs and Pamphlets. Received. A TREATISE on HUMAN PHYSIOLOGY, ETC., by John C. Dalton, M. D. Fifth Edition Revised and En- larged, Philadelphia, Henry C. Lea, 1871. - A TEXT BOOK on PATHOLOGICAL HISTOLOGY, by Dr. Edward Rindfleisch. Translated by Wm. C. Kloman, M. D., and F. T. Miles M. D., Philedelphia, Lindsay and Blakiston 1875. ESSENTIALS of PRACTICAL MEDICINE, by Henry Hartshorne, M. D. Third Edition Philadelphia, 1871 Henry C. Lea $2.40. MEDICAL OFFICE ** PUPILAGE, by John D. Jackson, M. D., Danville Ky, 22 T IEEE TER C T I I INT T C - [JAN. 13, 1872. VACCINATION and its PROTECTIVE POWER in WEST VIRGINIA. A report to the Governer Nov. 8, 1870 by John C. Hupp, M. D., State Vaccine Agent, Wheeling, 1871. THE RELATION of EPILEPSY to INSANITY and JU- RISPRUDENCE, by W. J. Conklin, M. D., Ohio State So- ciety Paper. - THE CLINICAL THERMoMETER, by Z. C. McElroy, M.D., Zanesville, Ohio. Reprint from Med. World, Oct., 1871. FourTH ANNUAL REPORT of the PUBLIC LIBRARY of CINCINNATI. THE MUTUAL RELATION of the MEDICAL PROFESSION, ITS PRESS and the CoMMUNITY, by Dr. Storer Jr. Re- print from Gynaecolog Journal, 1871. ADDRESS, Introductory to the 12 Regular Session of the Miami Medical college, by B. F. Richardson, M.D., Cincinnati, 1871. * ON CHRONIC HYPERTROPHY of the LIPS, by R. W. Taylor, M. D. Reprint from Med. World, N. Y. 1871. THE PHYSICIANs' DAILY PoCKETRECORD comprising a visiting list, many useful memoranda, tables, etc., by S. W. Bulter M. D. Philadelphia 1871 is the most complete, and at the same time, compact affair of the kind we remember to have seen. This is the only kind of vade mecum or compendium that should be allowed to be published. —sº-o-º- C LINHC AL MEMORANIDA. on the Therapeutical Value of the Hypodermic Injection of Ergotin in Haemoptysis. RY C. CURRIE RITCHIE, M. D. Physician to the Hulme Dispensary, Manchester, Experimental research has conclusively shown that ergot contracts the minute arteries, and by So doing in- creases the blood-pressure. A simple experiment will as Dr. Meadows has shown, be sufficient to establish the former of these propositions: thus, if a single grain of ergotin in solution be injected subcutaneously into the web of a frog's foot previously extended under a micro- scope, in a few minutes the circulation will be seen to become much quicker, then it will stop for a few sec- onds and oscillate in a spasmodic, jerking manner; after about half an hour, the blood-current will gradually return to its normal even, steady flow. The Well-known experiments of Brown-Séquard afford additional evi- dence on this point. He found that in the dog the Ves: sels of the pia mater contracted during its administration, just as with belladonna, but that ergot acted more pow- erfully on the cord than belladonna: both of these agents diminish the reflex power of the cord. The Bec- ond proposition, that the blood-pressure is increased, receives interesting corroboration from the recent re- Searches, chiefly with the haemadynamometer, of Dr. Ch. L. Holmes, published in the Archives de Physiologie, No. 3, for 1870. He finds that “ergot contracts the minute vessels by an action. on their muscular walls,” and “that this contraction augments the blood-pressure in the large vessels;” it is, moreover, found that pre- vious division of the vaso-motor nerves does not prevent the narrowing of the minute vessels, and that this diminution of calibre is also produced in the minute vessels of the lungs, causing a temporary diminution in the pressure of the systemic arteries. This last result has a direct bearing on the whole subject of pulmonary hemorrhages; and as it seemed to Dr. Holmes to be ca- pable of a scientific explanation, he performed numerous experiments in order to test its accuracy. Thus, he surmised that the effect might be due simply to the Sud- den introduction into the interior of the heart of a for- eign body, and accordingly he substituted other substan- ces for the ergot which he had injected into the jugular vein of a dog; but whereas the injection of ergot was with great rapidity followed by sudden diminution of the blood-pressure, which remained depressed for several seconds and then reached a higher level than before the injection, no such result followed the injection of the other substances. This sudden primary descent of the pressure-curve occurred after ergot-injection, even when it was introduced at a distance from the heart, and when the cardiac nerves had been divided previous to the injection; so that Dr. Holmes is led to the con-. clusion that the occurrence is due to contraction of the pulmonary vessels, “impeding or even preventing the passage of blood into the left heart, and so diminishing the flow into the arteries and lowering their tension.” Such considerations as these lead us to hope that renewed and extended investigation by those who have the opportunity of inquiring into the therapeutical ac- tions of the ergot of rye may assign this powerful agent its true place in our Materia Medica. An interesting paper published by Von Langenbeck in the Berliner Klinische Wochenschrift, No. 12, 1869, p. 117. “On the Hypodermic Injection of Ergot in Ane- urism,” contains the first account I can find of its ad- ministration by this method. He argued that, as ergot induced contraction of the smooth muscular fibres it would be a powerful agent in producing haemostasis, Two cases of aneurism, one in the right supra-clavicular fossa and the other of the right radial artery, were suc- cessfully treated by this means. Dr. Dutoit of Bern (Langenbeck's Arch. Bd. xii. No. 3), and others have successfully repeated this method of dealing with aneu- rism. In some editorial remarks appended to the med- ical periscope of the Elinburgh Medical Journal for July, 1870, a case is quoted where a patient who had bled to thirty-six ounces from the lungs, within a few minutes, had his hemorrhage completely checked in three min- utes by the subcutaneous injection of five grains of JAN. 13, 1872.] T EE THE C T , T TNT I C . 23 ergotin; and Dr. Allan Jamieson records a case in the British Medical Journal for June 3, 1871, in which the same treatment was successfully adopted in a slighter case. The last case attracted my attention to this mode of treatment, and I have since adopted it in eight cases, the particulars of which are now offered as data for judging of its value. The ergotin used was obtained form Messrs. T. and H. Smith, of Edinburgh, and a solution of five grains in ten minims of distilled water was employed, except in Case VIII, in which unusual irritation was produced by it; I therefore substituted a solution (prepared according to Langenbeck's formula) of three grains of ergotin, in equal parts of glycerine and rectified spirit, which produced very little irrita- tion. - [The Cases in detail follow. The remedy proved suc- cessful in every instance].—The Practitioner, Dec., '71. BROMIDE OF IRON.—This remedy is advocated by Dr. N. H. Norris, of Beloit, Wis. (North Western Med, and Surg. Journal), as nearly a specific in involuntary emis- sions and spermatorrhoea. He has administered it three times daily, an hour before or after meals, in doses of three to five grains, rubbed up in a little syrup. Prof. Namais (Practitioner) states that this remedy corrects defective formation of blood, and quiets nervous excitation, and produces the combined effects of iron and the bromides. He regards bromide of iron as being in many instances a therapeutic agent of Superior value in epilepsy even to the bromide of potassium.—Med. Record. - —º-o-º- A Successful Method of Treating Certain Cases of Dysmemorrhoea and Sterility. BY PROTHEROE SMITH, M. D. Senior Physiclan to the Hospital for Women, London. The plan which I then pursue is, first to prepare the patient by a purgative dose, and by abstinence from local excitement, and from alcoholic drinks, or much animal food, When hyperaemia exists, I scarify laterally the labia uteri repeatedly at the commissures of the labia, by which the vascularity of the organ is reduced and the shape of the ostincae, when constricted, is im’ proved. After accustoming the uterine canal to bear a metal bougie, which should be repeatedly and daily in- troduced, and increased in size until that of a No. 10 catheter can be borne without any pain, then the uter- ine dilator may safely be employed. It will be seen that this instrument consists of two short blades, two inches and a half long, the inner being continuous with the sliding shaft, with which it is nearly at a right angle, having at its proximate end a screw worked by a nut So as to mark precisely, by an index on the handle, the extent of dilatation employed. This should be used at first cautiously about every second day, always ceasing to screw as soon as pain is experienced. This is imme- diately relieved by a turn or two of the screw the reverse way. It will be found, in a short time, that the uterus be- comes accustomed to the dilatation, when it may be employed to a greater extent; and in the course of a few days or weeks, as the case may be, a forced dilata- tion to the extent of an inch or an inch and a half may be used with impunity. After this it will only be nec- essary to use the dilator daily for two or three days, and afterwards at longer intervals, to keep the parts open till they permanently heal in the state of distention effected by the operation. Time would fail me, were I to attempt to illustrate these remarks by a review of all the cases in which I have employed this mode of treatment. It must here suffice to remark, I have seen this practice followed by complete successin many instances, from amongst which I would quote the following extreme, but successful cases of dysmenorrhoea and sterility, treated by forcible extension and incision of the labia uteri. CASE I. A lady, aged 41, after sixteen years of mar- ried life without pregnancy, has since given birth to | two children. CASE II. A lady, aged 37, her husband hemiplegic from his youth, married thirteen years without family, and now has a living child. CASE III. A patient, aged 39, married twelve years, and barren, became the mother of a living child. CASE IV. The wife of a clergyman, aged 28, having been sterile for six years after marriage, was delivered of a living child. - CASE W. A resident in a distant colony, married fif. teen years, and barren, aged 38, became pregnant, but miscarried, in consequence of over-exertion at the sec- ond month of utero-gestation. - CASE VI. A delicate lady, aged 29, married nine years, but never pregnant, became so, and had a living child, followed by a second two years after. I select these few cases from a large number, because in all there existed more or less dysmenorrhoeal symp- toms, and three of them were complicated by consider- able structural disease, which had first to be removed before the plan of treatment I now advocate was adopted. In this paper I have endeavored, as far as possible, to confine my observations to facts capable of demonstra- tion; and I hope the experience of other members of this Association may confirm my own conclusion that forcible distension of the constricted os internum and incision of the OS externum only, in the manner de- scribed, in cases of obstructive dysmenorrhoea and ster- ility, is preferable to the operation by the hysterotome. The former is attended with less risk; and, with this impunity, it offers greater success, with the further ad- vantage of leaving the uterine tissue, excepting at its extreme mouth, without lesion.—Brit. Med. Journ., Dec. 16, ’71. - 24 [JAN. 18, 1872. T TH THE C T , T NTT C. CoMPRESSED AIR IN WHoop1Ng Cough.-No treat- ment has hitherto been found materially to shorten the disease. * * * * * * Now, however, the efforts of compressed airis stated by M. Fend to be a valuable meth- od of treatment. It was first recommended by M. Ber- tin and then by Dr. Sandahl of Stockholm, who reports no less than 102 cases rapidly cured by this means. M. Fend has also tried it and obtained extremely favorable results.-The Practitioner, Dec., '71. THE DISEASES OF ALASKA.—Dr. W. T. Wythe (Pac- ific Medical and Surgical Journal), in his “Medical Notes on Alaska,” states that bronchitis is never absent there; catarrh is seen at every change of the weather. Pneumonia often occurs, and in sporadic cases assumes a typhoid type. Rheumatism is very obstinate, and occurs very often, aud generally takes % the articular form. Tuberculous diseases are very common among both natives and whites. Phthisis pulmonalis runs a fearfully rapid course. Eczema is often seen, but yields readily to treatment. Syphilis is slowly but Surely killing all the natives of the north- west coast. Rheumatism, bronchitis, and scurvy are the prevailing diseases. lower portion of the radius often happen from accidents peculiar to the country, viz., trapping and rowing. Va- Tranverse fractures of the riola has never reached Alaska. —º-e'-º'- HOMIE NEWS. IF VIRCHow is really in earnest about leaving Berlin (which we don't believe) in search of more democratic institutions let him come to Cincinnati. Brown— Sequard's fate in Boston need not alarm him. Cincin- nati is sounder on the home talent question and Sister Anthony will give him a place at once. THEORY vs. PRACTICE.--When Vallandigham lay dying of a gun-shot wound in the abdomen the adven- turous Marion (Sims) sent out a telegram to his attend- ing surgeons, merely suggestive, you know, to cut down upon and ligate the bleeding vessels. “Many were the wounded at Sedam which might have been saved in this way” but were’nt on account of the timidity of the French surgeons. - Now what we want to know is this; When Mr. Fisk lay dying by the same accident at the Grand Central, New York, why did’nt the fearless Marion volunteer to go down into his bowels and tie up all the bleeding vessels and intestines and save his country this precious life 7 Medical College of Ohio. S P R J N G C 0 U R S E , * The regular eight weeks course of practical instruc- . tion for the Spring of 1872 commences May 15. Un- usual advantages are offered this year in the fact that the course will be conducted by the entire faculty of the College. The course will embrace the following topics: Clinical Medicine—Bartholow. Surgery—Dawson. ... " - Anatomy Brain and Nervous System—Gobrecht. Operative Surgery—Conner. « Obstetrics—Reamy. “ Ophthalmology—Seely. Female Pelvic Surgery—Palmer. Urinalysis—Nickles. - Physical Diagnosis—Cleveland. Fractures and Dislocations—Kearns. Microscropy—Whittaker. - Prof. Graham will deliver occasional lectures on Clin- ical Medicine and Diseases of the Chest during the pro gress of the Course. - The design of the Course is to present instruction in a thoroughly practical manner. Physical Diagnosis is to be demonstrated in the hospital wards; Operative Surgery, Operative Obstetrics, and Operative Ophthalmol- ogy, on the cadaver. . - The Dissecting Room will be under the supervision of Dr. where abundant material will be provided. Special attention will be paid to the chemical and mi- | croscopical analysis of morbid urine. - In order to render this course the most practical pos- sible, an opportunity will be afforded each individual of the class to make the various examinations and opera- tions on the living and dead subjects. Wednesday and Saturday afternoons will be devoted as heretofore to Medical and Surgical Clinics at the Good Samaritan Hospital: Two Daily Clinics will be regularly held in Cincinnati Hóspital, throughout the entire course; and a Daily Clinic will be held at the Dispensary of the Medical College of Ohio. One hour each evening will be devoted to Recitations on Anatomy, Physiology, Practice, Surgery, Obstetrics, and Materia Medica. The eminently practical nature of this course, and its shortness of duration, together with the great clinical advantages presented in Cincinnati, can but commend themselves favorably to the practitioner as well as the student. - FEES FOR THE ENTIRE CourSE, $10 As this Course does not count towards graduation, being cosidered supplemental to the regular winter course, graduates of the College are not required to matriculate. The matriculation of non-graduates is deducted from the fees of the ensuing winter session. William Autenrieth, No. 71 wrest sixth sTEREET, BETWERN WAINUT AND WINE, cincinnati, ohio, . III ſummºl. In Abdominal Supporters, Trusses, GLUBFOOT SHOES, - SPINAL APPARATUS, ETſ Keeps constantly on hand a full variety of * - & Metalie and ERubber syringes, stomach Pumps, Etc. STOCKINGS FOR WABDCOSE WEINS, special attention given to the fitting of Apparatus for Deformities. Mº Agent for DR. L. A. BABCOCK'S Silver Uterine Supporter, . ~. -ALSO– - DR. AHL SPOROUS FELT SPLINTs, –ALSO– T) A. Y. * S S T T, T N T S –AND– | tracted the attention of the most intelligent Physicians. - parent. W. Elliott's saddle-bags Flºrial Instrument. ExCEISIOR ELECTRO-MAGNETIC MACHINEs AND . GALVANIC BATTERIES. The Medical Profession is solicited to examine the valuable ſm- provements in electrical Instruments, Patented February 1st, 1870, manufactured by the GALVANO-FARADIC M’F’G CO. The recent re- searches of European Scientists in Therapeutical Electricity have at- Few can now dispense with Electrical Machines, although formerly abandoned, ow- ing to their inefficiency and inconvenience. These inconveniences are now abviated. Our instruments meet all the requirements of advanced science. They are the most elegant, powerful and cheapest ever offered. Combined simplicity, range of effects, and facillity of use. Always ready, require no preliminary preparation or assistance, no skill or experience and will remain in operation an indeffinite period. They produce the primary and secondary currents—the former in unequalled force. By a mere movement, either can be obtained without changing the Elec- trodes. THE FORIK is a peculiarity by which the rapidity of the shocks can be increased or diminished at pleasure—a therapeutical ne- cessity. On examination, other important improvements will be ap- There are FOUR SIZES of the Excelsior Electro-Magnetic or Faradic Machines: No. 1, small for family use, $10; No. 2, medium, for ordinary use, $15; No. 3, large, | for professional purposes, $20; No. 4, Double Cell, of great power, $30; There are three sizes of the Excelsior Galwanic Batteries: Eight Cells. $20; Sixteen Cells, $36; Thirty-two Cells, $60. Surgical Batteries, for Coutreization, of any size ordered. © THE RHEodeGos, or CURRENT GUIDE, Patented February 1st, 1870, is an entirely new contribution to Science, |by which total interruption, alternate connection and interruption, of inversion or the polarity of the current, is obtained by a mere pressure of the finger. We also manufacture Carbon or Gilt Steel Point Electrodes; Eye, Ear, Phrenic Nerve Electrodes; Catheters for Urethra and Uterus; Electric Scourges, Foot Plate, Tin or Carbon, Wires with or without Trocars. for resolution of Tumors, Tongue Plates, Rubber tubing, Battery fluid, &c. &c. Please call and ex- amine, or send for Circular to The Galvano-Faradio M'fg Co., No. 167 East. Thirty-fourth St, Cor. Third Av. New York, OPINION OF PROF. DOREMUS. College of the City of New York, cor. of Lexington Avenue and 23d Street, New York, November 7, 1870. I have carefully examined your new Electro-Magnetic Machine, with its valuable and ingenious improvements. I consider the In- stººlment the most complete, the most carded in its applications, a.º.d most convenient I have ever seen. R. O G D ENT DOR E.Jſ U.S. Late and Important Improvement.—Patent applied for. The Ex- celsior Machine Rendered Portable. Can now be carried around by city or sountry Physicians, charged and ready for use, without the posibility of spilling the Battery Fluid. DIVIDED MEDICINES, The Divided Medicine Com’y, CINCINNATI, OHIO. { The Company have the honor of bringing to the notice of the Profession, this NEW AND ExCEEDINGLY PRACTICAL METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. The Divided Medicines are prepared by FREDERICK KRAUS, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several squares must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MORE. - The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every square will consequently contain accurately measured quantities. But not only SolubLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINES. Ǻ - - "y sº. This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, ; : *, *, *, and even idoo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. - - Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE TO SPOIL BY ANY LENGTH OF TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calis with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. - For samples, Price Lists, and Agencies, address Medicine CQs IECX 2688, Or FRFDERICK KRAUS, Chemist and Druggist, Walnut Hills, Cincinnati, O. MR. FREDERICK KRAUs: - CINCINNAT1, February 15, 1871. *:3 Dear Sir–The specimens of your “ Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: - - SULPII:M0ſ: PPI II....................... % grain in each square. ARSFN:ACID.......................... 1-20 grain in each square. 4 4 CH IN INI ....................... 1. & 4 tº ſº. {{ CALOMEL.............................. 34 “ $ 4 46 • * COPPER ........................% ( & Respectfully Youes, ’’ E. S. WAYNE, Analytic Chemist. List of Pharmaceutical Preparations, MANUFACTURED BY Jozy Wºyazºr & Bºozººn, F.E.I.T.A.D.E.L.F.E.C.I.A. -º. ELIX. PHOS, IRON, QUININE AND STRYCHNIA, - ELIXIR OF GENTIAN FERRATED, ELIXIRVALERIANATE OF AMMONIA, (Goddard’s Formula,) --- - ELIXIR VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, Iron, with Phosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Iron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK, - - ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Hron, BITTER WINE OF IRON, Citrate of Hron and Peruvian Bark, —º- - FERRATED CORDIALELIXIE, ELIXIR CALISAYA BARK, WINE AND BISMUTH, ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, . - - FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, r TASTELESS COD LIVER OIL, TASTELESSCODLIVER OIL. FERRATED, BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and sherry wine, ELIXIR WALERIANATE OF STRYCHNIA, wine OF PEPSIN SYRUPSUPERPHOSPHATE OF IRON, EPSIN, - ELIXIR OF BISMUTH, COMP. FLUIDEXT, BUCHU AND PAREIRA BRAVA. * * STUIPIEPOSITOTERIES. Rectum, Waginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great &are, and of every variety of combination. Lists sent on application. * * SPONGE TENTS.—For the Urethra, of every size and style, made of finest quality of sponge. —- -*-*-- ---- - *** -** - -* - --- - -- -- - sº- -- - - *-- ---, -ss- *** :- * - -* - :- - -- * - - - -***-* - ºr-------- - --- *-*-*-* -- - - -- - - - --- - ---_E :=- ---º---- *-*-*-m-m- - *-*-*-*-m-sº *. - - --> - E: _ ==EEF --ºs- - - - • - -º-º-º-º-º-º-º- *-*- - *-*-*-*-ºs-sm- sº-sº º - . --→ - º - * > * -s-º-º-º- - *-* * - -*-*-ºs- —- ET - Sºº-º-º- * * ----------------e. 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The GOOD SAMARITAN HOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner ided with all the necessary ap- of sixth and Lock streets. It is handsomely furnished throughout, and is prov with commanding views, surround the whole house, and wide pointments of a First-class Hospital. Porticoes, entilation which is so essential to health and comfort. halls and abundant windows secure that full and free v Service is furnished by the sts.TERS OF CHARITY, Under the Superintendence of the well-known SISTER ANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. - { The regular Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each . Professor presiding over his own cspecial department. Patients may, however, select from the regular profession of the city any physician of their choice. - - esents extra inducements to Invalids throughout the State as a safe and The GOOD SAMARITAN HOSPITAL pr quiet asylum in any case of protracted illness, or in cases, more particularly, requiring Surgical Operation, where some stay is necessary in after treatment. - Rooms vary in price, according to the character of appointments necessary and service required, ranging, in general terms, between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand of service. Băș" Address, SISTEER ANTHON.Y., - 4 Hospital of the Good Samaritan, corner of Siaoth and Look, Sts., Cincinnati. Ohio- ROBT CLARKE & Co. PUBLISHERS, millºilº N0, 65 WEST FOURTH STREET, Call the attention of the Medical Profession to their Extensive Stock Of (ºuglish, Āmerican and freuth MELPIC-11, B00A.S. Paying particular attention to this branch of their business, they are enabled to execute all orders on the shortest notice, and at the most reasonable rates. Their facilities for the impor- tation of FOREIGN BOOKS, THE PROCEED- INGS OF SOCIETIES and HOSPITAL RE- PORTS are unsurpassed, and any orders en- trusted to their care will be filled promptly, and at the lowest rates. Fos"TER’s * IEP A TIENT Are furnished to Officers and Soldiers on Government a CCount. I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any dthers now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb—why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMEs A. FOsTER. 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cincinnati, Ohio, or 17.2 Jef- ferson Aves, ue, Detroit, Mich. SAML. P. THOMAS Subscriptions received for. FOREIGN and mºs AMERICAN PERIOD1CALS. All the New Publications received as soon as issued. Letters of Inquiry will receive our prompt and full attention. - Catalogues ſurnished gratis on application. ROBERT CLARKE & CO., Whilºlºmºnºlin PRINTERS AND BLANK BOOK MANUFACTURERS, 2eaders in Zaze. Medica?, ZZeological School, azed.//sce//azzeous Zooãs, G5 West Elourth Street, CINCINNATI, O. ID E A LEF IN English, French and Scotch G O O. Dºs, 34 West Fourth Street, CA.Ye.Z.º.º.º. Zºz. * E.s - 2& V N ſº : ~ | | *&~. s E. :s º i : -d |; - a H CINCINNATI. IET A C U L T Y. J A M E S G R A H A M, M. D., DE AN, Professor of the Theory and Practice of IMC edicine and Clinical JMC edicine. w. W. DAWSON, M.D., Professor of Principles and Practice of Surgery and Clinical Surgery C. D. PALMER, M.D., Professor of Medical and Surgical Diseases of Women. T. A. REAMY, M.D., Professor of Obstetrics and Diseases of Children. JOHN L. CLEVELAND, M.D., Demonstrator of Anatomy. CHARLES KEARNS, M.D., Assistant to the Chair of Surgery. ROBERTS BARTHOLOW, M.D., Professor of Materia Medica and Therapeutics. W. H. GOBRECHT, M.D., Professor of Anatomy. P. S. CONNER, M.D., Professor of Surgical Anatomy. W. W. SEELY, M.D., Professor of Diseases of the Eye and Ear. SAMUEL NICKLY'S, M.D., Professor of Physics and Medical Chemistry J A M HD S T . W H ITT A. Ex H. F. , - Professor of Physiology and Secretary of the Faculty. Janitor, College Building, Sixth St., bet. Vine and Raea, * T. Louis BRows, Prosector of Anatomy. CLI «s-ºs-ºs- PUBLISHED EVERY SATURDAY. T ERM s—$2.00 a Year, Invariably in Adyance. All Communications relating to Publigations must be addressed to the Editor: All Communicatións relating to Business, Subscriptions, Advertisements,"etc., to the Treasurer. Vol. 2, ... . & IN CIN N ATI, J 4 - > . . JAS. T. VVRITTAKER, M. D. - - - No. 101 West Ninth street, Cincinnati. Assocz.A.T.E. ºr rºofs. - W. W. D.Awson, M. D. THAD. A. REAMy, M. D. P. S. Conner, M. D. C. D. PALMER, M. D. W. W. SEELY, M. D. SAMUEI, NICKLEs, M. D. CHAs. KEARNs, M.D. Jno. L. CLEVELAND, M. D. - RobăRTs BARTHorow, M. D. Editor. W. W. SEELY, M. D., - - - - - - - TREASURER. No. 118 West Seventh street, Cincinnati. - club R AT Es. 4 Copies to one address......... ~~~~ ......# 7.00 {} * @ € $ I0.00 I 2 .84 “. ......... 18,00 C O N T E N T S. — - Page. º origiNAL ARTICLEs Medical Electricity and Medical Electrical Apparatus, by Roberts Bartholow, M. D. • * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * 25 l{*moval of a Uterine Polypoid Tumor, by A. Guthrie, MI. D............. 26 Čaronic Dysentery, Treatment by Chlorate of Potash, by E. Z. Shackleton, M. D.............. * . . . . . . . . . . “…...................................... 27 LECTURE . “linicaſ, on iñér Cirrhosis by Prof. Düchek of vienna, (From the Wiener Med. Presse, Dec. 10 and 17, 1871).................................. 27 - SCIENTIFIC NOTES The Pathology of Hydrophobia—Parasites of Small-Pox—Prize in Electricity “....................................... 20–30 MEDICAL NEWs ** The Actonian Prize–Novel Method of Inducing sleep—Medical Counsellors—The Palm to the True Victors—Testimony to an Italian Physician—The 44th Congress of German Physicians and Physicists............. i * t - º g º º q & s > g º º v c q x ç ç w g º & e º is tº $ tº º 30-32 correspond ENCE / . . . },etter from Mr. Stanton—An Explanation........ " \º. ........92 REviews ...' Neuralgia and the Diseases that simulate it, * ºf F. E. Anstie, M. D.—Reoprt of the Commissioner of Pensions to the Secty. of Interior for 1871,............... a * * tº tº e º is a º ºs s CLINICAL MEMIoIRANDA Ergot in Dysentery—New Treatment of Hydrocele, etc.—Vaccina- tion Papers—Quinine in Trachoma–Gonorrhea Treated by Water—A New Treatment of Spleen Tumors—Sulphurous a tº a tº e º g º º a tº ſº ºr e º 'º º q is a s is tº it * Acid in Contused Wounds—Cause of Infectious Diseases......33-35 HOME News..... * * * * * * * * * * * * * * * * * * * * * * * * * * * * g º ſº e º a e g º g g g g g is ..............36 The Gºod Samaritan Hospital................... .................36 **** Now is the time to subscribe for THE CLINIC. The new Volume is just commencing. Over one hundred new sub- *ribers are already entered this month. Back numbers *e disappearing fast, * * * ***...-----> ...........32-33 . {T} &J e A N U A R Y 20, 1872. No. coars are co- Fashionable Hatters IMPORTERS AND MANUFACTUREIts or ŁABHES” Fººs, 92 wrest FOURTH st'. Opposite Post Office, CINCININATI. & Special Inducerments to Medical Men. * - pg|ART Still MA !- ºb ES GNERS ASP. J. TAFT, W. T.A.F.T. Editor Dental Register J. & W. TAFT, TXTEINTTISTS 17 WEST FOURTH STREET, CINCINNATI, O. A Monthly Journal, CONTAINING 48 PAGES, Devoted to the Interests of the Dental Profession, - * , * Hills&SH No. 65 WEST FOURTH STREET, Call the attention of the Medical Profession to their Extensive Stock of &nglish, American and french wrorcºr moors. Paying particular attention to this branch of . their business, they are enabled to execute all || - º ‘. . Jºe ~ . - - - * < . - v. & - - - - - - - - *, * , 4. . ^ i. - ^. • - , , . ~ * : * * * * *. . . . . . . • * : . w S, - - * . ." * - - - - - * - * - #: “y” . - - -- -- • # , , , , . . . . * - - - -- - || - g | | |, ...' º . . . ; ; ; . :-- , . . * : us i . . . ... ', . : * : *** - - - : '.' . . . . . . . ‘. . . . . . . . . . . . . . : || || || || . : ºr * , - m. BMWERN WINt nu VINE, MANUFACTURER OF AND DEALER IN Abdominal Supporters, Trusses, GLUBFOOT SHOEs, orders on the shortest notice, and at the most| . . . . reasonable rates. Their facilities for the impor- | tation of FOREIGN BOOKS, THE PROCEED- INGS OF SOCIETIES and HOSPITAL RE-| PORTS are unsurpassed, and any orders en- | trusted to their care will be filled promptly, and at the lowest rates. Subscriptions received for FOREIGN and AMERICAN PERIODICALS. All the New Publications received as soon | as issued. Letters of Inquiry Will receive our prompt and full attention. - - -. Catalogues furnished gratis on application. RobHRT CLARKE & Co., whilºlº, mºtiºn PRINTERS AND BLANK BOOK MANUFACTURERS, Zealez’s a Zºº...?/edica/, ZŽeological, .Sc/oo/, and .7//sce//azzeozzy Zooſs, 655 West Fourth str. eet, - Keeps constantly on hand a full variety of - Metalic and Rubber syriages, stomach Pumps, Etc. ‘stockings Fon warticose veins, “-º- Special attention, given to th eff tting of-App aratus for. Deformities. - —ALso— • ‘’ - DR AHL's PORöUS FELT, SPLINTs, —A LSO– . . . . . . . . . . . . . . * , - . . . . . . . . . . . . . . . . . . . . .”. . . . . . . - . . .” • * : * ~ * ~ * > . - - --- - - - - - ... • “. - - . . A. ' *:S , , ºf Tº T : T.: Tººr rri c ve £--> \- .2 - - - - ~\sº . . . ~ * S. 3 ºz. . . | 1 || tº .. .. | Nºs —AND— CINCINNATI, O. º - • i * . . . . . . - .* ... " - -- ~. • . . . . . ºr . * . . . . . * - 1 . . ; - '-º'- ~f *** - º - *S*. * * . . . i -> * : - * > , - . 23 - . . . . * * , - - . . * * : - $s... Yºſer ºilić tºº...ºſité *-i- ºr - t • . - - ... - - -> - .* * * - - - - * . , - . - . . . . . . f. , ' ' ', . . . . . . . . . . ...-a, - ". . . . . . List of Pharmaceutical Preparations, won.w mºrezºn 4 anorman, F.H.I.E.A.D.E.I.P.E.C.I.A. ELIX. PHOS, IRON, QUININE AND STRYCHNIA, ELIXIR OF GENTIAN FERRATED, ELIXIRVALERIANATE OF AMMONIA, (Goddard’s Formula,) . . ELIXIR VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, Irons, with Phosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Iron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK, - ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER winE OFIRON, Citrate of Iron and Peruvian Hark, - ," FERRATED CORDIAL ELIXIR, ELIXIR CALISAYA BARK, WINE AND BISMUTH, & • ‘ ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, - * FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, - TASTELESS COD LIVER OIL, TASTELESS COD LIVER OIL. FERRATED, - .* BEEF, IRON AND WINE, Extract of Reef, Citrate of From a had sherry Winne. ELIXIRVALERIANATE OF STRYCHNIA, WINE OF PEPSIN SYRUP SUPERPHOSPHATE OF IRON. OF PEPSIN, " . - - ELIXIR OF BISMUTH, COMP. FLUIDEXT, BUCHU AND PAREIRA BRAVA. stſ E*E*Oslº DOERIEs. Reetum, Vaginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great eare, and of every variety of combination, Lists sent on application. * SPONGE TENTS,--For the Urethra, of every size and style, made of finest quality of sponge, -*- *S*_º ſº ſº - - -- ** Wm. Wilson McGrew, .Wo. 77 Wasz. Fourzºn, Sznarr, PIKE's OPERA HOUSE BUILDING, Importer and Dealer '-º'-wºº, I N Wºrwººeee- - Diamond and Gold Jewelry, sº Watches for Ladies and Gentlemen, Sterling Silver Tableware, Bronzes, Antique and Modern, Marble and Bronze Clocks, Marble Statuary, FAN cºr Coons, GENER ALLY. Carriage Manufacturer, Nos. 9 and 11 East Sixth Street, bet. Main & Sycamore. I MARE NOTHING BUT czar'ss ºro w A'. Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur passed. Of - Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive variety ºf light elegant designs of different cost and finish. In vehicles especially adapted to •º- PHYSE&#AAS” (SE. The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. The superiority of my light gentlemen’s buggies, road and, trotting wagons, and racing work of every description, has long -------- - - - -** * -- ~- F. E. Suutº. E. S. WAYNE T. E. Suire & Co., WHOLESALE DRUGGDSTS, IM. A. N. U E A CT UER IN G. gh exists A. N. D PHARM Aceutists, CITYCIN NATſ, OHIO, Have constantly on hand a full assortment of S EX, X: Cºſ’)S)O X}}{3 O G, S ANYO meoworses, cxxxºny)(CAX, AX'X'A}{A}^0 S, rests. Medical glass ware sº, sº, And solicits the patronage of the trade and profession. We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, ties. FINR, ANTD FRAEH, CHEMICALS. Of the popular class ºf preparation3 known as H. LIXII ER, s, We manuſactiſe a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. Bitter Wine of Iron, An excellent Chalybeate and loſic, Wine of Iron, &c AGENTS FOR BULLOCK & CRENSHAW'S Sugar-coated Pills and Granules. Y Price Lists of preparatious and of Sugar-coated Pills sent by Mail upon application. The long standing and well and widely known repu- tation of our house we offer as a guarantee for the reliability of our preparation, and the quality of the good" sold by us generally. Made in accordance with the U. S. P. and other recognized authori- i { TR.s.IN.INMARSH's º, "tº º JAMEs Fostºn, J.R., & Co. Instrument Makers and Practical Opticians, Beg leave to return thanks for the patronage extended to them through a long series of years (having been established since 1836), and in the reorganization of their firm will endeavor to merit a continuation of the same. We wish it understood by the Profession and the Public generally that our invariable rule is, to make or import none but the best in. struments. Those in want of any of the acknowledged good aids of vision to imperfect eyes, will always find the best” and largest stock of Lenases, Spectacles; and the best models procurable, with pains- } taking skill to adjust them to all conditions of sight, at our house. Special attention paid to orders for Fine Microscopic Objects and Microscopic Apparatus, Magnifiers and Readers in great variety.' Medical:Batteries, Earometers, Thermo- meters, Hygrometers, Urinomieters and ſtain Gauges. of the most approved construction always on hand. All orders promptly and accurately filled. ' ' ' ' ' ' . . . . . . . JAS. FOSTER, JR. F. S. Säääki ºpp, ; ** JAs. FostER, JR. & co. S.W. Cor. Fifth & Race Sts., Cincinnati, 0. §2) TRUSSES. c992 . No. 758. BROADWAY, NSW. Yoak HAWE, been in the habit of applying and recommeriding the Truss manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined. I.EWIS A. SAY RE, M. D. Surgeon, Bellevue Hospital. From Prof. Willard Parker to S. D. Townsend, M. D., Surgeon to the Massachusetts General Hospital. BEG leave to state for the benefit of all concerned, that I have known Dr. S. N. Marsh the last fifteen years. * * * I am in the constant habit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hornia. He has instruments superior to any I have ever seen, and his treatment is unattended with any of the risks to the patient that exist in many of the plans suggested and attempted to be carried into execution. I have confidence in Dr. Marsh as a gentleman of honor and integrity, and as such recommend him to the members of the medi- cal profession generally. WILLARD PARKER, MI. D. Professor of Surgery, New York City * Dr. S. N. Marsh's Patent Radical Cure Truss, and all other kinds of Trusses, Shoulder Braces, Supporters, Elastic Stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Cure Truss Offices of S. N. MARSH & CO., No. 2 Vesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. OPPOSITE THE HIGH STEEPIE, o) sºlubot You s! }\tol,lili) duolls tº otou A puu Sosuo auðI put ox&I to oldthyms ‘sloo quitºſ--- I ox A.lo)) tº oſtili.All: ; ) olqu').[0,1 out) Jo Sozºs ool (Il aan, 0.Iolſ.I. ‘pollsap st: ‘īrīsoup NH ou? quouſly A do ll), A pull at upo soilollug ou.L "poliſt; lululu pſule. Alojºuq out, Jo Injuou)s out) put: “poluovoid SI uo!) -biode.Ao on pun—uonor Jo Juo UAVulp out: Koul outſ] (tota 's]]sodop put soldquºt stº) tuouſ posinolo Allſånolou? ote sequid ouT, soould oAlloadsø. Houſ uſ poxg AIULTJ 5ulaq ‘oinoes aroul patapuol out suoquio put Sossº) Niomug ouj, poutiqo atu sºurinapu lººtout loulo ooutº Ajuluoo snoruošut sºul AgI laulo out, utol) ouabdos utoba ‘ssed upo soluld ouſ?, put u0(tal:O our loſt|A Ad poppaold ore sºns to sºutuado—uleleuſ) sple.Mu.A0p splio, -xo ‘Iloo qobo Jo tuo, eul on 5utpuodson too “ºutſ to AO0 sun go ošublj V pox, KIqb.Aotuut soutooed tºsop.AH oul Nog (outu to Wol aun on s.Saxl opiluoodSI oup $uſtim? Nā ‘outſou ºpjuſt snd otojoq “pot touliſ oth on Soddo (){} {}{S * jo subout Aq ‘O toddus Iulluo) to utuod uopoo.W out, i ittoſ, papuodsns out 2 q sould uoqtuo pub outſz ou.L ‘potonspiritupu Kºſoſºloolºſ Jo Khnutmb out 3up -IIonuoo Snu1—plulºſ Átoºlbºl out uſ postoluuſ og Kuut soluld on 1 Jo alou.A out do uoſº Iod u Kluo Juul os pauſing oq ūuo SAoSI ou I, sočut ºujºt ºu utoqn 5uſtumn Kq ‘uong Aoto pollsop out ºu pottſbºot puts ‘poto won to posſeſ oq truo slo) out] In A ‘xogſ touttſ ouſ ‘s.Sox osotin Agt ‘osuo tonno aun III hols tº liśnotuſ] *xogI tolluſ oun onuſ dIIs puto (Ioto ºu ‘g a S.Kox UoT 'polymbol trouſ w poxout -0.1 od urbo II upſula, Aq ‘V V SøIpuru H 3TſpIIS. pauſoe, -ju on; Xoq SI(Il ol, punl&L Atollèg oil] IQſ Setogldaool oil) out: osau.I. 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To poddons Kitſappus od utio 1 ſtolino oil (IoIIIA Aq “I ‘Iolumnuluto) tº poropio uſou A poliotºu Şſ opils spun ol, pool:Id sº q Ioſu.A 10Ao slo) Jo Joduinu ou? tuouſ ‘sopoulook I oth on Sossed luolino otºl HoſtEA, Iſānoiſ]] ( * (a ty (x oul ăuţpuolloiduroo uſ poolto! Tedxo oit upo Agnogºp ou taxa.Aoû ‘topbot out, otojoq 0]uid out, unſ.A smººted -du eq, Jo so.Inneaſ as Inouſ sſp ouſ puſtu ou ol quosolidol uto lunoooº tºdia.A ou Anq ‘Attoum.Insuſ sºul Jo uoaſă St. A lionditosop Jaj.Iq (; Taded tout.IQſ tº uſ XLIOX AoN Jo Kuudu(OO 5upiniouſnub IN optºtt: I-Oubaltº) alſº Aq pogſpout su Āto]]uq opul:ATB3 algºrod Iottloons out Jo od&l -011ooto jūollooxo In: AOIoq quosold on aſqº att; a A\ ‘9 togun V. ‘(I Ju ‘Aonohuštva SIRIqaoyſ X:I * - • s an at .1 ºr tº di V 1 * * : * > * * I & I I at . I p → H. P. W. Mr. * , | 3 H J J & © I SI I * 5 p > IA — , () —- * * : "I Q R. J., 3M W "I W N I #} R 3 (). ‘(I oppis oſqu'AoPW tº poorld sºutbog out uO splibq SSBIq C& of NITFEd H. H. L. […ISI ‘0& 'NV [. 26 THE CLINI c. [JAN. 20, 1872. Same, with Hydrostat attached - 23 00 | During each paroxysm of pain the tumor gradually No. 2–sixteen Cells, for General Use - - 3500 descended, and at length during one of unusual severity, - With Hydrostate - - - - 40 00 on the 18th, it was partially expelled from the uterine No. 3.-Thirty-two Cells, of Double Strength i cavity. where increased power is necessary, At 4 A. M. of the 19th she had another.paroxysm of and for Electrolysis - - - 60 00 pain, followed by excessive loss of blood which was with With Hydrostate - - - - 7000 difficulty restrained. At 10 A. M., assisted by Drs. The additional cost of the “Commutator,” if ordered Keables and Wilkin of this place, I applied a silk liga- for each of those Batteries, is $3.00. ture with Gooche's double canulas. Just as the liga- For a portable Battery this arrangement is the best ture had encircled the neck of the polypus, a copious that has hitherto been proposed. No Portable Battery, gush of blood occurred, which was inmediately arrested however, can work as satisfactorially as the permanent | by tightening it and again occurred upon relaxing it. arrangements described in a previous number of THE |The ligature now was drawn tight and firmly secured. CLIN1c. For permanent use the cups of Siemens and |The patient being much exhausted from loss of blood, Halske, and the regulator of the Galvano-Faradic Com- etc., was ordered two teaspoonſuls of brandy with one pany seem to us to be the most desirable. grain of opium to be repeated if necessary. --—--→–- A portion of the tumor having already sloughed, it now became doubly necessary to use every precaution to prevent Septicamia; accordingly she was ordered to RY : inject, per vaginam, Sol. Carbolic Acid (grs. xv to aqua Oiss) overy four hours. She slept some through the night, had no recurrence of pain, but the stomach was very irritable and would not tolerate quinine or any form of iron. - I was called April 8th, 1870, to see Mrs. R. act 34, On the morning of the 21st, the foctor was intolerable, who was suffering excruciating agony from violent and with a view of lessening the chances of blood- throes resembling labor pains, except that they were poisoning 1 ordered, Carbolic Aeid, grs. xv, Alum Wa- more continuous; she was bathed in perspiration and |ter Osº, to be injected, per vaginam, every two hours, tossing herself from side to side in bed. Upon inquiry hoping that the astringency of the alum by corrugating I found that she had suffered more or less at her catame- the tissues would, to a certain extent, prevent absorp- nial periods for three years, but much more so during tion of the poison. . . The ligature was tightened each the last year, which had also been attended with con- alternate day. She had no recurrence of hemorrhage, siderable loss of blood. The catamenia resumed regu- but had occasional attacks of diarrhoea, which were larly, and continued from six to eight days; during the kept in abeyance with Bismuth and Opium, Huxham's interim she was quite free from pain, but was much Tincture, Brandy and a nourishing diet: these were con- annoyed by leucorrhea. She had been married fifteen tinued until the 31st, when making gentle taction on the years but never been pregnant, her general health was canula it came away. The tumor was so large that it considerably impaired; appetite poor, bowels regular. Was removed from the vagina with considerable diffi- No organic disease of thoracic or abdominal organs. culty. It was pyriform in shape and fully as large as a Ordered Morph. Sulph., gr. at once to be repeated pint cup, and when laid open had the appearance of a overy half hour till the pain abated. On making a solid mass of flesh interspersed with fibrous tissue. digital examination per vaginam, I found the os Subsequent to this, she improved quite rapidly and somewhat dilated, soft and patulous, and a small tumor was able to sit up in ten days and was quite well in a presenting itself just within, seemingly as large as an month. • . egg. On the 9th she had another severe paroxysm of She menstruated regularly and without any abnor- pain accompanied by copious hemorrhage, for which mal trouble, on the 4th of the following July, the she was ordered Acetate of Lead and Opium. menses recurring every two weeks for three months, After the menstrual period had passed I made a specu- after which they became regular every month and have lar examination and found the tumor just within the continued so up to the present time (Nov. 23d, 1871). uterine neck; it having receded farther into the uterine | When conversing with her yesterday, she told me cavity on the cessation of pain. After explaining to that she had no more Pain during her “periods” now Mrs. R., the real nature of her case and the necessary than when she was 15 years of age. The pedicle of the opcration, I prescribed some iron and quinine and tumor Was remarkably large and must have been almost awaited the next menstrual epoch, which returned on an inch and a half in diameter; which partially accounts the 8th of May accompanied by a repetition, in an for º length of time the ligature was in cutting its aggravated form, of all the former symptoms; the hem- wº #pal points connected with the case are: orrhage only being controlled by frequent vaginal injec- || 1st. The immediate cessation of hemorrhage on tight- tions of alum-wator. ening the ligature. - Removal of it [terine Polypoid 'ſ'ku naaor. .A. ( ; UTHR1ſ., Mſ. D. Pella, lowa, JAN. 20, 1872.] TIEI IET: C T , IIST I C . 27 2d. The magnitude of the tumor. 3d. The largeness of its pedicle. - 4th. The possiple influence which the alum-water may have had in preventing absorption of putrid matter. - This case is reported in the hope that it might be of some value to those who are compiling statistics of “Uterine Tumors and Neoplasms.” --—-—e-e—e------ -- - - - - c H R o N I C D Y s E N T E R Y . some Further Testimony in favor of the Employ- ment of Chlor. Potash in Chronic Dysentery. - BY - E. Z. SHACKLETON, M. D. The successful employment of Potass. Chlor. in the treatment of Chronic Dysentery, reported by my friend Dr. A. B. Isham, of Walnut Hills, Ohio, in the The Clinic of Nov. 24, prompts me to add my testimony as to the efficacy of this medicine. Case 1. Mrs. A., German, aged 29, well nourished, was attacked July 11th with dysenteric stools, bloody and frequent. Some tenesmus and tormina. Treated herself with domestic remedies until July 22, when I was called to attend her. Found upon examination , the disease had passed into the chronic form. Stools frequent and Small, presenting a purulent ap- pearance, flakes of lymph, etc. *Tenesmus and tormina greatly increased. Abdohen full, tender upon pressure, Prescribed - JR. Ol. Ricini 3ss. Ol. Terebinth. Tr. Opii aa, gtt. a. TM. To be taken at once. This caused evacuations of scybala smeared with a muco-purulent material. - Having had good results from the administration of Pot. Chlor. in several previous cases, I determined to resort to it at once; accordingly, I prescribed Pot. Chlor. ten grs. every 4 hours; together with 1-5 gr. Morph- Sulph. sufficiently often to ensure freedom from pain. Saw patient again on 23, when she expressed herself as feeling much better. Stools not so frequent, tenesmus and tormina not so great. This treatment was persevered in, -except as pain became less, when less morph. was giv- en until wholly stopped on the 25th. Aug. 1st she was dismissed cured; discharges having become healthy in appearance, abdominal pains absent, etc. From this time she rapidly gained strength. Case 2. Fred. K. also a German and well nour- ished, age 55, Called to attend this man July 23, found he had been suffering with dysentery four days, stools frequent, small and bloody; lower bowels full. Gave full dose of Mag. Sulph. to carry away offending accu- mulations, and deplete inflamed mucous surface; operated promptly and fully. Patient not improved, gave Opium and Plumbi Acet., formentations to abdomen; also injections of Tr. Opii in thin starch water to re- lieve tenesmus, which it did to some extent; treatment continued until 26th, patient no better. Then changed to the Ipecac treatment, 3 gr. Morphia to quiet stom- ach, and in ten or fifteen minutes gave 20 gr. dose of Ipecac which was tolerated, gave this every 4 hours; continued this until 30th, discharges less frequent, but present a purulent appearance. Patient considerably debilitated. Stopped Ipecac and substituted Pot. Chlor. gr. x every 3 hours, Morphia sufficiently often to ensure rest. Continued treatment until Aug. 7th, when patient came to my office saying he was perfectly well. - Of course this prompt benefit could not be obtained did we not commence treatment soon after the assump- tion of the chronic form , extensive ulcerations would not so readily yield. St. MARYs, OHIo, Jan. 1, 1872. --------—-º-º-º--------- - - I, I ºf E R (; I R. R. H. O S H S . A Clinical Lecture by Prof. Houchek, Viennina. [From the Wiener Med. Presse, Dec.,10 and 17 1871.; ('onfinited from No. 2, Let us turn our attention now to the local origin of the disease. In the inflammations mentioned transuda- tions occur from the vessels themselves, from those parts, namely, where the inflammatory process has developed. That we have here before us an inflamma- tory lesion is improbable from the fact that the fluid in the abdominal cavity is free. Further we have estab- lished the fact that the spleen tumor present is not re- ferable to former disease which may have left it as a residuum. Finally this is not in harmony with an idiopathic peritonitis, wherefore we need not delay over the presumption of such an inflammation. Other facts assist us. If we direct our whole attention to the vena porta we may establish all the symptoms, develop them, indeed, therefrom. Stasis in the portal vein— I speak of its trunk or its chief branches—must necessa- rily occasion disturbances in the circulation of its various branches. If the trunk of the portal vein, the collecting canal of all its branches, be subjected to com- pression, the whole mass of blood is forced back upon the mesenteric, splenic, gastric, etc., veins. The best example of this is furnished in simple portal thrombosis wherein the roots of the vein are distended in high degree, the splenic vein thus is engorged with blood, in 28 [JAN. 20, 1872. TEEE CI.INI c. the substance of this organ as well, and the spleen with this increased volume presents itself thus as a tumor. It is not yet definitely determined whether this result is a simple phenomenon of stasis or whether there is not also associate with it alterations of tissue. Patholog- ically, we know that the spleen often enlarges rapidly, assuming a great increase in its volume. Spleen tumors are often encountered of such size as to extend two or three inches below the border of the ribs. Hard and firm they seem in consequence of the great distension of the capsule from the proliferation of the spleen substance which continually occurs. A second and much more frequently observed stasis presents itself in the roots of ! the numberless vessels which go to and from the mesenteric vein. These are vessels which ramify in the peritoneum, in the mesentery, upon the surface of the intestines, in the substance of the intestine itself, vessels which reach the liver through the mesenteric veins and through it finally the gentre of the circulation. A | stasis developed here must become evident in the intes- tine and the peritoneum. The exudation mentioned must then occur in the peritoneum very early and the same effects ensue as in the feet after ligation of the crural vein. When pressure is exerted upon the mesentery, ascites develops, as a further consequence, stasis in the intestinal vessels, transudations into the interior of the intestines, diarrhea, and if the process be rapidly developed, as is the case in portal thrombosis, the extremely distended vessels are ruptured and hem- orrhage occurs. In regard to these intestinal hemor rhages, however, I must remark that they occur from many internal causes. When ascites and spleen tumor are absent in such cases, the diagnosis may not be estab- lished. There are cases marked by has matemesis where the cause of the hemorrhage may not be assigned. The Yemae gastricte which empty into the Yenal splenicae may induce, in consequence of stasis in the Yena porta, stasis in the vessels of the stomach and though this may not lead to any marked exudation of fluid, it may and does not infrequently lead to hemorrhage. All this, however, is not symptomatic of granulated or cirrhotic liver, not symptomatic of any liver diseaso necessarily, symptomatic simply of stasis of the portal vein. The same manifestations are present when the portal vein is subjected to compression, when a thrombus is formed in its interior or extends into its branches, when, finally, there is such disease in the liver as to occlude the caliber of the numberless branches of its final rami- fication. * We are thus far, then, in our disease as to be able to diagnosticate some impediment to the cireulation of the portal vein ; that we may state, moreover, that this dis- turbance has its seat at various points, that it is in the trunk of the vessel or in its branches, because we find present ascites and tumor of the spleen. In further diagnosis we have now to regard at what point of the vena porta the obstruction must exist to evince the lesions present. It would lead us, to-day, too far from our purpose were we to discuss all the possibilities of such cases. We confine ourselves, therefore, to the most essential. Here belong, then, diseases which concern the branches of the portal vein and which extend thence to its trunk, diseases of the peritoneum and intestine. I need only remind you in the present case, that the history points to no such affections. There has been in our patient no previous dysentery, no intestinal dis- ease of any kind. He has slowly passed from a condi- tion of perfect health into that manifest before us, Our examination reveals no disturbing element, as tum.or from the pressure of which upon the short trunk of the vessel between the liver and duodenum these symptoms might ensue. We could establish nothing in this whole region other than the described condition of the liver. From the absence, then, of any extrinsic compression upon the portal trunk or branches we are cast back upon the liver. - - - How, now, may these disturbances in the portal circu- lation occur 7 Lesions may very early, as is readily understood, affect the branches into which the portal vein breaks up. When the chief of these branches are compressed, stasis must ensue. These cases are rare. It is possible that cicatrices following inflammations tumors, neoplasms in the liver may compress the portal branches. One of the diseases that furnishes most abundant new formations is carcinoma. But this dis- ease show this most remarkable peculiarity; it causes these portal disturbances in only the rarest cases. Ascites, it is true, does often occur, but the stasis is never 80 great as to induce an increase in the volume of - the spleen. On the contrary, we find quite early a marked reduction in its size, so that it is present but as a seeming appendix which must be sought after to be fonmd. This is because its tissue, under the metamo- photic changes of the new formation, becomes atrophied. It is attacked, with marasmus. We encounter the cause of these portal disturbances seldom, then, in the chief branches of the vein. We find the most frequent cause of the lesion to be connective tissue exuberations in the substance of the liver. One form of this affection is present in the well known granulated liver, liver cir- rhosis. Bessdes this there are various atrophic condi- tions which lead to connective tissue proliferation though only to moderate degree. Thus in the simple form of atrophy consequent upon that fatty degenera- tion which is caused by protracted hyperaemia, in simple hyperoemia, in heart disease of some years duration, we find the liver firmer and more solid, granulated lightly, too upon its surface. The connective tissue increases in volume, the liver becomes harder and firmer and these circumstances exercise, then, an influence upon the portal branches. The most fruitful source of con- nective proliferations is furnished by simple inflamma- tory processes, hepatitis, thus, a disease which is, how- ever, extremely rare in our climate and syphilis of the liver, an affection which produces, in those parts where retrograde change has commenced, opaque, whitish, JAN. 20, 1872.] THE CLINI c. 29 shiny cicatricial tissue either in linear or rounded form or in bridles with branching processes. - This cicatricial formation in the liver is, according to late investigations, not so very rare, and the masses of connective tissue often encountered in the liver with whose genesis we were quite unacquainted ten or twelve years ago, we have learned in the last few years to re- gard of syphilitic origin. The amount of stasis in syph- ilis of the liver must depend upon the amount and dis- tribution of the lesions peculiar to the disease. Such a mass in the right lobe would only affect a small number of portal branches, only an insignificant stasis, thus, would ensue, and this would be compensated for in other unaffected vessels. I have seen cases in life which have been marked by all the symptoms of liver cirrhosis, wherein a more thorough examination has revealed numberless cicatrices of syphilitic processes elsewhere in the body; treated, then, as cases of syphilis, cure has resulted. Syphilis is, then, a fruitful source of connective tissue proliferation and of stasis in the portal circulation. But the most frequent cause of these phenomena is liver cirrhosis. We understand by this a disease processin which there is symmetrical new formation of connective tissue. Of this, there are at most, but two varieties. The liver is permeated with masses of connective tissue, in a sense, new and foreign to it. It encroaches upon the interspaces for the portal branches which are com- pressed. The circulation in this vein is more and more interfered with until full stasis is brought about with the consequences present in the case before us. We have here a case of hydrops ascites not referable to changes in the mesenteric veins or in the portal trunk, as also a spleen tumor inexplicable on any other assumption. Our case implies a central impediment, in all proba- bility situate in the liver. The only other tenable theory would be a compression exerted between the liver and the vena cava an accident of such extreme rarity that it may be safely left out of account. Hay- ing established this we may now inquire what are the symptoms which atrophy of the liver presents. It should be first remarked that the influence of this dis- ease is different in different cases and at different times, so different, indeed, that many distinguish between a preliminary stage and a stage of attack. The liver is sometimes found large or moderately enlarged so that it is palpable beneath the border of the ribs; with this increase of size are present the symptoms of liver cir- rhosis, but on post-mortem the granular surface is want- ing. Masses of connective tissues are evident, unsy- mentrically arranged, without cicatrices, without granu- lation on the free surface or on the surface of section. It may be maintained that this is the preliminary stage Which may remain for a long time, not being attended With atrophy of the parenchyma. I may add, too, that We encounter cases wherein the process induces marked *ites, marasmus and death without any atrophy of * gland. Many have claimed this as a particular kind of cirrhosis in which the liver becomes enlarged and hardened from the rich proliferation of connective tissue in its interior. But it is as rational to maintain that this is but a preliminary stage and that in conse- quence of the rapid changes in the nutrition induced there has not been time sufficient for retrograde change and consequent atrophy: that when the process is more protracted this atrophy always ensues. Hitherto we have only been able to state that there must be stasis in the whole portal circulation for the production of these symptoms. Whether this stasis, however, be due to connective tissue proliferation is still sub judice. If a case be marked by liver enlarge- ment with a distinct border, other causes leading to stasis, particularly, liver syphilis, hyperamia from heart disease and other causes being excluded—or on the oth- er hand, if a case be marked by liver decrease, its border not being palpable at the moment of deepest diaphrag- matic descent, the diagnosis is more Secure. I may re- mark to you that the condition described in the books you will seldom encounter. The deductions of phantasy from the autopsies of exquisite cases are seldom realized in life. The fingers can not penetrate in palpation much more than one-quarter of an inch: elevations of an inch in hight may thus exist and escape detection. Granulations are flat and low, and may but very seldom be recognized by touch. I believe that in many cases in which they have been recognized, they have been products of syphilis. I remember to have treated a case of syphilis in a woman at the Josephinium hos- pital, where numbers of granulations of half an inch in hight were plain to the touch. To resume now in conclusion for to-day, we may ac- cept a case to be cirrhosis of the liver in all probability, where there is stasis of the portal system, when this stasis is inexplicable by other diseases, and where, further, splenic enlargement is present. Should there be associate with this a small liver and hob-mailed to the touch, the diagnosis is fixed. Confirmed, it is still further by a history of the abuse of spirituous drinks. —-tº-º-º-------- SCIENTIFIC NOTES. 'The Pathology of My drop in obia. An Abstract from the Prager Wiertejarschrift, No. xxiii, 1871. -* The symptoms just portrayed are regarded by many physicians and authors as characteristic of a specific inoculation from the bite of a rabid animal. But there are many eminent authorities who refuse to regard hydrophobia in man as a specific disease, and who deny, indeed, the possibility of human infection. Prof. Bruckmüller states in his interesting essay on hydrophobia, that all the symptoms claimed for hydro- phobia, according to his most abundant and varied ex- perience, occur in the most different disease processes; i) * } : - **— , t - .*, tº -- … . . * * *--- pneumonia, brain cancer, diseases of the prostate, etc.; further, there is no single pathological characteristic of hydrophobia found universally in all bodies dead of this disease: every lesion present may occur in other diseases. Hydrophobia, therefore, is no specific disease, but only under certain circumstances a prominent symp- Concerning its contagion, Bruckmüller maintains there are more facts against it than in its favor. Firstly, the symptoms of hydrophobia in man are very different from those in dogs, the most marked symptom of the disease in dogs, e. g., the desire to bite, is absent in man. Hydrophobia presents the most marked analogy to traumatic tetanus, may, indeed, only be distinguished from it by the cause of the latter. His conclusion is, therefore, that hydrophobia in man, when induced by the bite of a dog is nothing else than tetanus. Observe the statistics of dogs bitten by a mad dog, this is a strong fact against contagion. According to Hartwig, but 6 in 137 are affected ; the rest remain healthy. Inoculation imparts the disease in about 15 per cent of cases. In many cases entirely different diseases follow inoculation, typhoid fever, catarrhal processes, lung inflammations, Inoculations with blood are totally without effect. | Gºtc. Lorinser, also in Vienna, in his extremely interesting work on this disease, demonstrates the untenability of the prevailing doctrine of the contagion of hydrophobia. The transmission of a specific contagion from the dog to man, belongs, he claims, to the region of fables. There are no characteristic symptoms of this disease; what do exist prove only that the dog is sick and inclined to bite. Pathological sections exibit no characteristic lesion. Hence, Lorinser maintains that what has been called hydrophobia is not a definite disease, but is only a symp- tom of many and very different affections, - Concerning the disease, now, known as hydrophobia of man, the author is of the opinion that it is mistaken for convulsions, tetanus (perhaps from trauma, as well from cold, mental emotions, cycesses, all, however, in no con- nection with madness), hysteria, cramps, etc. Certain it is, that persons bitten by dogs, do sometimes in conse- quence either of wound, severe caustics applied, intense anxiety or of extraneous causes, become attacked with tetanic symptoms. In support of this are arrayed the following facts: 1. Hydrophobia sometimes originates without any cause whatever, without a previous bite, scratch or lick from a raging animal. - - 2. Among the great number bitten it is only seldom | that one is attacked with hydrophobia, Sladtburgen treated 12 persons bitten by a mad dog. But one be- came sick; he recovered. Cramer states that of 100 bitten in Hamburg, in 1852-3, only one died of hydro- phobia. - 3. In many cases, º occurs months or years after the witt: ; how may this be explained 2 processes which present no analogy to hydrophobia, as | (same as in trismus and | water. tom of the most diverse diseases (a view already expressed| by Köchlin). It is, then, to be regarded as a secondary manifestation, often induced by external influences. T C - [JAN. 20, 1872. 4. The course of the so-called hydrophobia as well as the lesions in the dead body differ not in the least from the symptoms and pathology of tetanus. Cries of pain are regarded as barks, convulsive twitchings of the mouth for attempts to bite; difficulty of swallowing osophageal cramp) for fear of * . 33 w º: 5. The course of diseases known to be induced in the body by the transmission of poisons from the lower animals, presents not the least resemblance to hydro- phobia. - Supported by all these facts, the author comes to the conclusion that hydrophobia in man is not an effect of animal poisoning; it is not a specific disease; it is noth- ing else than a neurosis. (trismus, tetanus) which may supervene upon trauma, occur as well from many other causes. PARASITES OF SMALL-Pox,-Weigert found in the corium of sections of the skin in small-pox vesicles or sacs of 0.01-0.02 mm. diameter which he with Reckling- hausen considers as lymph vessels whose contents ex- hibit the characteristics of bacterians as described by Recklinghausen. He found them only in hemorrhagic cases and in localities in the vicinity of the efflorescences of the disease; he does not believe, however, that they are peculiar to small-pox. In what relation they do stand to this disease he is not yet able to state.—Cen- tralbl.f. Med. Wissen, No. 39, 71. . PRIZE IN ELECTRICITY-By a decree, dated April 18, 1866, of the Minister of Public Instruction in France, a prize of 50,000fr, (2,000l.)was offered for the most useful application of the Voltiac Pile, the period for competi- tion to expire in April 1871. From a report of the minutes presented by the President of the Republic, it appears that candidates are few in number, and that in the opinion of the 8&vants to whom the memoirs were submitted, none is of sufficient merit to have earned the prize. By a decree of the 29th of November, the com- petition is now extended for another period of five years, to terminate on November 29, 1876, MEDICAL NEws. THE ACTONIAN PRIZE.-The next Actonian Prize or prizes offered by the Royal Institution, will be awarded * ſ | in the year 1872 to an essay or essays illustrative of the wisdom and beneficence of the Almighty. The subject is “The Theory of the Evolution of Living Things.” The prize fund is two hundred guineas, and it will be awar- ded as a single prize, or in sums of not less than one hundred guineas each, or withheld altogether, as the managers in their judgment shall think proper. Com- petitors for the prize are requested to send their essays to the Royal Institution, Albemarle Street, on or before June 30th, 1872, addressed to the Secretary, and the adjudication will be made by the managers in Decem- ber, 1872. - " . . JAN. 20, 1872.] TEEE C LINI. C. - 3] A NOVEL METHOD OF PRODUCING SLEEP IN IN- | FANTs.--Dr. Curren, writing in the Dublin Quarterly Journal of Med. Sci., of the Medical History of the Him- alayas, speaks ot a curious way which the woman of the country have of quieting their children when obliged to leave them. When a mother goes into a field to work, or is otherwise unable to take her child with her, she selects some sheltered spot near a stream, in which she places some straw for a bed for her infant, and then di- rects, by means of a piece of split bamboo, a current of water, of from one to two or three inches in diameter on its uncovered occiput and temples. This produces a soporific effect, which generally lasts as long as the water continues to flow. The sleep is said to be very soothing, and children who have been much subjected to its in- fluence are known to have been unusually free from the annoyances incidental to the period of dentition. MEDICAL COUNSELLORS.–Jas. Paget, D. C. L., F. R. .S. S., (Lancet), in a clinical lecture on “Dissection Wounds,” in connection with his late illness, remarked that Sir William Lawrence used to say that he had not known any one to recover on whose case more than seven had consulted. Our art has improved. He had the happiness of being attended by nine: Dr. Burrows, Sir William Jenner, Dr. Gull, Dr. Andrew, Dr. Gee, Mr. Caesar Hawkins, Mr. Savory, Mr. Thomas Smith, and Mr. Karkeek. lors was safety. THE PALM To THE TRUE VICTORS.—“The Prince lives, and every day gives us assurance that the great danger is over. But surely those who have undergone trials only inferior to those of the snf- ferer himself are not to be forgotten. If the nation re- joices and is thankful, it ought not to be forgotten what it owes to the skill and science, to the devotion and Self- sacrifice, in every sense entire and complete, of the physicians. Sir William Jenner would be the first to extol the exertions of the colleague who has earned from all at Sandringham what he values probably only second to the approbation of his conscience, the deepest grati- tude. In Dr. Gull were combined energy that never tired, watchfulness that never flagged-nursing so tender, ministry so minute, that in his functions he seemed to combine the duties of physician, dresser, dispenser, Valet, nurse—now arguing with the sick man in his delirum So, Softly and pleasantly that the parched lips open to take the scanty nourishment on which depended the re- serves of strength for the deadly fight when all else failed, now lifting the wasted body from bed to bed, now wash- ing the worn frame with vinegar, with ever-ready eye and ear and finger to mark any change and phase, to Watch face and heart and pulse, and passing at times twelve or fourteen hours at that bedside. Ánd when that Was over, or while it was going on—what a task for ... |-to soothe with kindest and yet not too to º .* yº †: was º great tº bºº, confidence. †h.”. ºair; . É. to justify ings I hear, and it is only just that º º be known, for very certain it is that from º of Whom they are said not one word of the truth like s would ever come.”—Dond. Corr. N. Y. Daily. He says, in this multitude of counsel- +- TESTIMONY To AN ITALIAN DISTRICT PHYSICIAN.— The municipality of Castiglion d'Orcia has presented Dr. Comparina, district medical officer of Campiglia, medical works to the valne of 140 lire(£5:12), in rec- ognition of the zeal and devotion with which he has per- formed his duties, L’Imparziale regards this as a rsre instance of public generosity, and hopes that the exam- ple may be frequently followed. - -————-º-e -º- The 44th Congress of the German society of Physicists and Physicians. Rostock. Sept. 18-24. 1871. Certainly the most enthusiastic, perhaps the most profitable session ever held by this learned body has that proven which assembled for the first time under a united Germany. Most instructive papers were presented in every department of science. We have space but to notice a few of the most prominent from the section on internal medicine. The next congress assembles at Leipsic the place where the Society was founded half a century ago. Prof. Leyden, (Königs- berg) read a paper on the peculiar character of the ex- pectoration in bronchial asthma. It is scanty, -1 drachm in 24 hours, grayish-white, and transtucent. It contains masses of fine fibrils and flocculi of considerable tenacity and usually a light gray color. These fibrils and flocculi are derived from the finest bronchioles and are composed of mucous corpuscles in retrograde change, dry and granular, with a mass of elongated, octahedral crystals visible under the microscope at 300-600 diame- ters. These crystals are imbedded in a basis substance consisting of cells in retrograde, granular, metamorphosis. Between these cells, granular masses are encountered in molecular motion. Similar crystals are observed in dry catarrh, croupous bronchitis with asthmatic com- plications, mucous tumors, leucocythaemic blood, and in the spinal cord. They are quite brittle, colorless, easily soluble in warm water, alkalies, and dilute acids, Prof. L., is inclined to accept the view that this peculiar secretion mechanically, perhaps also chemically, excites in the smaller bronchi an irritation in the vagus termin- ations in the bronchial mucous membrane with reflex contraction of their muscles, and thus the symptoms of nervous bronchial asthma are produced. An experi- mental proof cannot yet be furnished. Matters thrown into the air passages of animals never penetrate to the finest bronchi. In regard to therapy the remedies in highest repute are chloral hydrate, opium, ipecac, iodide of potash and inhalations of alkaline fluids. Prof. Waldenburg (Berlin,) demonstrated his Cesophagoscope and a quicksilver manometer. By means of the first the lateral walls of the upper part of the Oesophagus may be brought into view. The manometer which is connected with the mouth by means of a sac is designed for measuring the force of inspiration. It is 32 [JAN. 20, 1872, TIH. H. cI.TISTI c. of high importance in a diagnostic point of view in that unlike the spirometer it does not take into account the force exercised by the muscles. Inspiration and expira- tion moreover are separately measured and may thus be compared. º: 3: Prof. Liebreich (Berlin) on crotonchloralhydrat as a narcotic. [Chemistry omitted.] In animals this agent brings about anaesthesia of the head, under continued action, of the rest of the body; in the second stage there is absence of reflex excitability in consequence of affec- tion of the spinal cord; in the third, under-large doses, death follows by paralysis of the medulla oblongata. Animals may, however, still be maintained alive by means of artificial respiration since the action of the heart is not at all affected. Chloral, on the other hand, finally induces paralysis of the heart. It would seem from its action that dichlorallyle is formed in the body and this is analogus in its effect to aethylidenchloride. Experiments on man demonstrate that the brain may be brought into profound narcosis by crotonchloralhy- drat without interfering with the functions of the rest of the body, while with chloral a corresponding amount of brain narcosis is attended with general anaesthesia and dangerous reduction of the hearts activity. * * Prof. Binz (Bonn); On the effects of quinine on haemoglobin. According to former experiments fresh blood of warm blooded animals, which have received quinine in doses this side of fatality, shows distinctly diminished reaction to the stimulus of oxygen. By new experiments, by means of the direct action of quinine on haemoglobin and fresh blood, B. has demonstrated that haemoglobin dissolved in a dilute solution of quinine, remains protected against decomposition and oxygena- tion for a long time while the protecting solution becomes of a bluish-red color and of disagreeable odor. –Schmidf's Jahrbücher, Dec. 1, ’71. -—º-e-º--- ~~ ("@IRRESPONIDEN (‘E. CINCINNATI, ()., Jan. 16, ’72. EDS. CLINIC : In THE CLINIC of January 13th under the head of “Medical News” is an item speaking of the death of my brother Dr. Stanton, of Pennsylvania, as “Suicide by Morphia Hypodermically,” and stating that the dose taken was one grain. The dose taken was but little, if any, more than half a grain, and the case was not suicide. No one who knew my brother has the slightest suspicion that the case was one of suicide, in fact those who were cognizant of the circumstances knew that it was not. Will you please make these corrections in the The Clinic and oblige Yours Truly, William Stanton, It E VIE W S . NEURALGIA AND THE DISEASES THAT SIMULATE It. By Francis E. Anstie, M. D. For sale by Robert Clarke & Co. - We have been promised this book for some time through the London Practitioner, and now welcome it to our library. The author professes to put forward “substantially a new view” on the subject of neuralgia, which was briefly mentioned in his article in Reynold’s “System of Medi- cine,” three years ago. The subject is presented under the following divisions. Clinical history—Complieations of Neuralgia—Pathology and Etiology of Neuralgia— Diagnosis and Prognosis—Treatment. This completes part I. - - - - Part II is devoted to the diseases that resemble neu- ralgia—Myalgia—Spinal Irritation—The Pains of Hy- pochondriasis—Pains of Locomotor Ataxy—Pains of Cerebral Abscess—Pains of Alcoholism. Chap. I. Clinical history is very instructive, and is highly satisfactory, but it encroaches somewhat upon the chapters devoted to pathology, etiology and treat- ment. The characteristic feature of the book is devel- oped in the chapter devoted to pathology and etiology, viz., the theory that all neuralgia is of centric origin. He hopes to be able “to convince most readers, that the essential seat of every true neuralgia, is the posterior root of the spinal nerve in which the pain is felt, and that the essential condition of the tissue of that nerve root, is atrophy, which is usually non-inflammatory in origin.” This theory is maintained by a consideration of the etiology of neuralgia and the kindred neuroses, clinical observations, hypotheses, etc. Showing how peripheral irritation may produce centric degeneration . and centric degeneration pain. The chapter is rich in research and suggestion, but we fail to come to the same conclusion with the author and prefer, until some further advance is made in the pathology of the disease the “inhibition theory” of Handfield Jones. It does not appear but that a trophic degeneration of the cord, would be as plausible an explanation as a degeneration of the posterior root. The chapter devoted to treatment is in pleasant contrast to the majority of monographs and systems of practice that we meet with, whose prin- cipal strength is given to the etiology, symptomatology, pathology, etc., while the treatment of the disease in hand is merely briefly mentioned. Treatment here is as thoroughly discussed as the size of the book will admit, and fully represents the most enlightened and approved methods. The part devoted to the examina- tion of diseases resembling neuralgia closes this truly interesting and instructive votume. The fact that the author has been a-sufferer from the painful disease of which he treats, for years past, will lend to the book the increased charm of personal ex- perience, by one who was capable of noting and reason- ing from what he felt. JAN. 20, 1872.] .. TIH. H. C.L.INI c. REPORT of THE COMMISSIONER OF PENSIONs to the Secretary of the Interior for the yearending June 3, '71. —Upon examination of this interesting report, (sent to “THE CLINIC” with compliments of T. B. Hood, M.D., Chief of Medical Divison Pension Bureau,) we find that on the 30th of June last there were on the rolls 207,495 pensioners of all classes, receiving in the aggregate $33,077,383 63. Nearly 100,000 men of average not ex- ceeding 35 years were in receipt of invalid pensions on the 1st October, a price was peace secured. The tabulation of the several classes of injuries and diseases and their relative propor- tions has been admirably done, and will make the re- port of much value for future reference. The more. strictly business details of the operations of the Bureau will not so particularly interest the medical men of the country. The remarks on examinations and medical examiners are at once true and worthy of most careful consideration. That the affairs of the Bureau may be so administered as to do justice to the Government and the disabled, there must be competence and honesty on the part of those medical men upon whose reports of existing disability the Department at Washington must base its estimate of the propriety of allowing pensions and in what grade ; and upon each judgment of these examiners, payments for a period of ten years are made. When so much expenditure of money is to be made it behooves the U. S. Government to select and retain first class examining surgeons, and to do their work properly, compensation must be made for the services rendered. It is to be hoped that the suggestions of the Hon. Commssion- er of Pensions on this subject may be duly heeded by Congress. So too, as there must be an examination at Washington of these reports of medical examiners scattered over the whole country, such examination must be made by a thoroughly educated and specially trained chief of the Medical Division of the Bureau Prudence and economy alike dictate the formal recognition of such officer in the Bureau, making him second only to the Commissioner himself, and the paying him such liberal salary as will secure the right man for the place. Judg- ing from the report before us we think the country fortunate in having in this Pension Bereau such men as the present. Commissioner and Chief of the Medical l)ivision. - - - ----——sº- © -º---- - - - - - . . C J, INIC AI, WIEMORAN ID.V. on the Employment of Ergot in Dysentery. Paris Academy of Medicine, Séance. Oct. 10, 71. This note is presented to the Academy by Prof. Gub- ler in the name of M. Luton, Prof. of the clinic at the Ecole preparatoire at Reims, - During the epidemic of dysentery which prevailed in Reims towards the close of last summer and which has What an army of sufferers—At what 33 not yet entirely disappeared, I employed against this malady with varying success, most of the anti-dysenteric agents reported most efficacious. Our epidemic became severe, recovery ceased to be the rule. The action of medicines was not evident; the most of those attacked, particularly among the aged, succumbed to the disease. It seemed to me then time to seek for some new method of medication which might furnish results more satisfactory and more rapid. There came then under my treatment a female affected with both memorrhagia and dysentery. This gave me an op- portunity of trying the ergot of rye, whose employment is so efficacious against one of these diseases. Both af. fections were favorably influenced by this remedy at once, and after a few doses constipation was produced. which lasted at least four or five days. This attempt was repeated soon upon cases of simple dysentery. It always acted kindly in a very short time, amelioration soon occurring, afterwards complete re- covery. I gave the ergot in powder, three grammes [45 gr.] per day in divided doses of 50 ctgr. I have likewise prescribed ergotine in pilule or solution in cor- responding doses with the same advantage. Two or three days suffice ordinarily for complete cure. In grave cases of course longer time is required. Ergot does not attack the hemorrhagic element of dysentery only, but the malady in its entirety, the mu- cous secretions, tenes)nus, the colics, the fever are as well made to experience its good effects, and this in the first few hours of treatment. In one case marked by grave symptoms, as algidity, the reaction was as prompt as emergetic. The patient, an aged female, had taken only six grammes of ergot in two days and recovered completely. The number of patients treated in this way has not been large nor has the use of the drug been very extensive; but I believe I am justified to-day in signalizing public attention to this method of treatment, marked as it is by the rapidity of its effects and by the constancy of its action. I am prompted, therefore, with the intent of giving to these facts the widest possible publicity to address the Academy in this manner.—Bull de Therap., Nov. 30, 71. NEW TREATMENT OF CYSTS AND HYDROCELE.-M. Munod communicates the following to the Paris Sur- gical Society. The immediate cause of cysts and of se- rous accumulation in normal cavities lies in the pre- dominance of Secretion over absorption: treatment should be directed to the restoration of the equilibrium. Three years ago I was consulted by an individual with a voluminous goitre. I diagnostrated cyst of the thy. roid gland. By way of confirmation I made an explor. ation with a fine trocar when an amber colored fluid escaped ; when the cyst had again filled itself anew I practised the following operation; by the aid of a hy- drocele trocar I drew off a coffee cup [French] of seros- ity and injected an equal quantity of alcohol at 40 deg. Fifteen days thereafter I repeated the operation. In one month resolution was complete. No recurrence has - 34 [JAN. 20, 1872. TIH. H. cI, IISTIC. tion for a hydrocele. I removed a very little of the serum and injected one gramme of alcohol. Eight days thereafter the tumor had diminished. I now made a second operation ; fifteen days after it, a third. tient has been perfectly well for six months. In another amber liquid and injected one gramme of alcohol at 40 deg. This patient like the others resumed his occupa- tion immediately after the operation. Some days after, I made a second operation when the tumor entirely disappeared. Finally in a third instance, my own in- dividual case, a hydrocele formed the size of a hens egg. I made the puncture and the injection. On the same day I walked at least an hour. The liquid has dimin- ished considerably but has not entirely disappeared. By the proceedure of my employment the vaginal tu- mic is not destroyed but is restored to its normal condi- tion. I believe this treatment will be found valuable in hydrorachitis, ovarian cysts, hydrarthrosis, etc.—Bull. de Therap., Nov. 30, 71. VACCINATION-PAPERS.—Small-pox having entered our hitherto healthy town, there has been a great de- mand for vaccination; and I have, at times, found difficulty in keeping up a regular supply of lymph. To meet this, I have devised a new method of lymph pres- ervation; it is most portable, and very certain in its effect. Taking asheet of common sized (i. e., cream-laid) note paper, I paint it with fresh lymph taken from the vesicle with a fine camel-hair pencil. The lymph soon dries; and the paper is ready for use. When required, a minute piece may be cut out or torn off the sheet, and, after having been slightly breathed upon, should be stuck upon the freshened surface. If the paper be re- quired to be kept for any length of time, it should after being charged, be covered with a thin coating of white of egg. Isinglass will not do, as it cracks when dried— Preston—Brit. Med. Journ., Dec. 23, '71. QUININE IN TRACHOMA.—In the treatment of granu- lar pannus associate with blepharospasm, Bader (Guy's Hospital), has seen rapid and favorable results from the external application of sulphate of quinine. The anti- septic value of this preparation induced him to try it in granular lids, on the theory of the possible parasitic ori- gin of this disease. As much as could be held on the point of a small knife blade, is dusted upon the inner surface of the lower lid with a camel's hair pencil. The secretion is somewhat increased thereby, but photopho- bia and corneal affections quickly diminish and the granulations speedily become smaller.—Berlin Klin., Wochusehr., Dec. 4, '71. GONORRHEATREATED BY WATER.—A few weeks ago THE CLINIC contained a notice of the successful treat- ment of this disease by simple injections of water. Strong confirmation of the efficacy of this simple method is furnished in the following note. Dr. Castex (military service) recommends in this disease thirty injections of manifested in three years. A patient claimed my atten- My pa- fresh water per day. By this means the duration is shortened and the intercurrence of complications pre- vented. In no instance did haematuria, cystitis or orchitis occur. In no case were painful erections observed. |Castex treated in this way 312 patients mostly attacked |within 9 days. case of voluminous hydrocele I drew off a soup cup of These were treated altogether 4475 days an average of 14 days each. The same ratio was ob- served in 33 cases treated later in like manner. All these patients left the hospital perfectly cured having been kept each 2 days after recovery under observation. Of these 16 returned, however, with a recurrence of the disease.—Rec. de mem. de med, 3, axiv. ----------—sº- e-º-------- - - , , A New Treatment of Spleen Tumors. -- BY FR. CHvosTEK, M. D., Vienna. An Abstract from Schmidt's Jahrbücher, Dec. 1. ‘71. The first attempt to faradise the spleen in the living subject was made by Ziemssen, who was of the opinion, however, that it was only in cases of pathological and considerable increase in volume that this organ could be reached by the electric current. His method was to place one pole on the inner surface and one on the outer surface of the gland. He did not demonstrate any reduction of volume. He used moist electrodes—a method unsuited for excitation of deep seated organs, because only so little current penetrates beneath the surface. Chvostek attempted to reach the enlarged or- gan in a reflex way, by excitation, namely, of its vaso- motor and trophic nerves. To effect this, he faradises the integument of the splenic region with two pencils, by means of the Secondary current of an induction apparatus. - - - From the 16 cases detailed it results that by the method of faradisation cited, a marked influence upon the spleen tumor of intermittents may be effected, indeed, he was successful in most cases in inducing resolution of the organ, not only in acute, but also in chronic cases. The reduction effected in mediately after each session (two minutes) was lost to some degree in the intervals, yet the organ never regained its pre- vious size. Every succeeding session reduced the tumor somewhat. % *S* % . Of the individual cases detailed, the second is of spec- ial interest on account of the great volume of the tumor and on account of the great reduction effected in the first session of but two minutes duration. His reviewer states that, since the first publication of Chvostek’s ex- periments, he has had the opportunity of repeating them in a series sf cases, eight in all, and that he can confirm the results from his own experience. In acute tumors (four intermittent, two typhoid spleens) he was able to effect a marked reduction in volume very soon after the sessions. In his chronic cases the application remains without effect, even after ten minutes session, * * JAN. 13, 1872.] Quite lately he succeeded in bringing about a marked reduction in a leucaemic spleen tumor by Chwostek's method in the case of a man 33 years of age, whose en- tire left abdominal cavity was filled by an immense spleen. The blood in this case showed a marked increase of white corpuscles even after months of treatment with iron and quinine. The treatment first mentioned greatly improved his general health and diminished the propor- tion of white corpuscles in the blood. “In the last tem weeks there was no further reduction in the volume of the spleen. It extended upwards to the lower border of the sixth rib, protruded beyond the thoracic arch some 9 centr. and broadened out in the axillary line to 11 centr, diameter. I now commenced electrical excita- tion of the splenic region. From the very first session reduction commenced and continued up to the sixth (most marked, however, after the first), when no further diminution could be effected, probably on account of such organic changes as to place it beyond the power of any therapeutic agent. Microscopical examination of the blood showed no difference, before and after elec- tricity, in the quantity or proportion of white cor- puscles. SULPHURous ACID LOTION IN THE TREATMENT of CONTUSED WOUNDS.—Dr. John Balfour states that an extended experience has given him great faith in this application. It gives almost instant relief from pain, controls and greatly restrains suppurative action, and, where possible, secures primary union perhaps as effi- ciently as carbolic acid. The lotion is of the strength of one in twelve; a thin rag (the thinner the better) should be laid over the wound, and kept constantly wet for the first thirty-six to forty-eight hours. When cold becomes less agreeable, the lotion is used tepid, the rag being wetted every twelve hours and covered with gut- ta percha. Where primary union is taking place, about the third or fourth day, a dressing of zinc ointment is to be substituted for the washing: this allows the skin to heal. When suppuration is established, a zinc lotion may be used after a week or ten days, and the cure Wrought out on ordinary principles. Dr. Balfour records the following, amongst other cases:—S. B., a lad between eleveſ, and twelve years of age, on the 8th of June, in company with some other boys, was amus- ing himself with gunpowder; a “peeoge” (or devil) hung fire, and he poured some powder on it from the flask. This of course exploded, and tore open the metacarpal Space between the thumb and forefinger of the right hand. The metacarpal bone of the thumb was fractured, and both wrists scorched. A mass of the short flexors of the thumb was forced out of the wound, contused, torn, and blackened. As this muscular substance was much injured and could not be returned without using undue force, a good deal of it was cut off; the wound Was Washed out with the sulphurous acid lotion, covered with **ag wet with the same, and the fracture was kept 1Il position by tying the thumb to the forefinger. Had à fair night's rest; the wrists (not complained of yester- T H E CI I IN.I.C. a tº gº Jú) day) now painful and beginning to vesicate; dressed with carbolic acid and oil. Everything went on well, the burns on the wrists healed kindly, suppuration was most moderate, cicatrization rapid and perfect. Dr. Balfour lately passed the boy into a public work, with a thumb very little, if at all, the worse for the accident. —Edinburgh Medical and Surgical Journal, Nor., '71. CAUSE OF INFECTIOUS DISEASEs.--Dr. Balfour also showed, Med. Chir. Soc. Edinburgh, a piece of lead soil- pipe which had been inserted into an iron pipe just below the seat of a water-closet. The iron had been corroded, and a way of escape thus made for the poison- ous sewer gases into the house. This specimen had been removed from a house in which two fatal cases of diph- theria had occurred last summer; and Dr. Balfour stated that in his experience some such source of gaseous leakage had been invariably found, when sought for, in every house where diphtheria, typhoid fever, and other allied disorders had prevailed.—Edin. Med. Journ., Dec., '71. -——º-º-º--- - - - - Hoyitº NEws. . REMOVAL.--Dr. A. Schwagmeier to 650 Elm Street. THE specimen of a most remarkable case of intestinal invagination was forwarded to this city by Dr. Shackle- ton of St. Marys, Ohio, and was made the subject of a pathological lecture at the Good Samaritan on Saturday last. The subject will be worked up for THE CLIN1c as soon as a full history of the case can be obtained. THE number of patients registered and treated at the College Dispensary thus far this month is 158, T)R. CONNER's paper on the Excision of the Ganglion It is noticed in the last number of Virchow's Jahresher, der of Meckel continues to attract foreign attention. Gesammt. Med. DR. UNZICKER's paper on the use of Polygonum Hydropiper in Amenorrhea is noticed in the last num- ber of the British Medical Journal. Vaccisarios chPAPER THAN SHAvisa-iſ there is any one fact calculated to make a man believe that he dwells among Hottentots in the midst of a howling wilderness it is the following action of the Board of Health of this city as reported in the Gazette of January 10th. “Mr. Thomas presented a resolution to pay the dis. trict physicians $25 each for services in Vaccinating children in the public schools. “Mayor Davis moved to amend by paying them ten cents per capita for pupils vaccinated, Lost, and the original resolution was them adopted.” Shortly after reading this magnanimous procedure we chanced to meet one of the district physicians, and upon inquiry learned that he had been compelled to examine both arms of 2600 children, 400 of whom he had vaccinated. In several districts, the labor was even greater than this. The time required for the ex: aminations and vaccinations was three weeks. For this he was awarded $25. Scarcely one, we venture to state, but lost more than that every week in the time necessarily consumed. Six cents for protecting the life of each individual from this fearful scourge, to say nothing of checking the spread of the epidemic over the city, to the mansions of the Royal Board itself as well. As we have no desire to practice medicine in families where the value of medical service is thus ap- preciated we do not hesitate to enter indignant protest against this shameful prostitution of our science. The Board of Health, we are happy to state, constitutes but a very insignificant part of the population of Cincinnati. - - - . . . . . -- - - - - - --- *. - . . . Deformity, 1. Concealed Nipple, 1. Unbilical Ulcera- (orrection—The Spring Course of 1872 commences' . . . . . . . • & . • ? March 15th instead of May 15th as erroneously stated in our last issue. —e-e—e-- - - - - - ----- ----- 'A'ine Gºod samaritan Hospital. º THE following statistics show the work done in this excellent institution. * .. . . . . Whole number of patients admitted since Oct., 1866, Of these were discharged cured - 4,070 212 104 º or relieved, 1)ied, Remaining lec. 31, 1871, - * * - - Of the 212 deaths, 63 were due to consuumption, aud !) were from serious injury, the patients living but a | few hours after reaching the hospital. Including the deaths from all causes, it will be per- ceived that the ratio of deaths is somewhat less than 5 per centum, a mortality rate which ranks this Hos- pital with the most successful in the world. , , Of the whole number of patients admitted, 1,373 were wholly provided for at the expense of the institution; from its own resources, without aid from public taxa- tion. There were cared for as pay patients 3,018; but many of these paid Small sums which did not reimburse the hospital for the outlay on their behalf. It is true many of these paid liberally; otherwise, so many of the maintained at the public expense. |Chorea, 3. Hysteria, 2. | tirpation Nail, 5. | absolutely indigent poor could. not have been provided It will be perceived them, from these figures, that the Good Samaritan H ſospital has dispensed a noble charity Without being a burden on the tax-paying public, it has cared for the poor who in the City Hospital are * The great opportunities for medical instruction, such |an institution affords are best appreciated by the selec- tion of a few of the most prominent cases from the diff. erent departments of medicine as presented to the clinical, class during the past three months. as tº * Aphtha, 1. Medical Cases—Locomotor Ataxia, Atropia Poisoning, 1. Epilepsy, • . . . Hematuria, 1. Rheumatism, 5. Endocarditis, 2. Hydrophobia, 1. Pneumothorax, 1. Pleurisy with Effusion, 1. Dysentery, 4, Phthisis,8. Obstetrical, etc., Cases.—Puerperal Mania, 1. Foetal tion, 1. Lochial Suppression, 1. Endometritis, 1. Mām- mary Abscess, 1. Amenorrhea, 1. Molar Pregnancy, 1. Puerperal Fever, J. Eye Cases and Operations.—[ritis, 8. Paracentesis, 5. Iridectomy, 3. Cataract Operation, 1. Operation for Malposition Punctum, 1; for Epiphora, 5. Acute Gran- ulations, 4; Chronic, 5. Acute Keratitis, 2; Chronic, 8. Abscess Cornea, 1. Opacities Cornea, 6. Staphyloma, 3. Operation for Strabismus, 2. Suppurative Keratitis, 2. Operation for Trichiasis, 6. Excision Eye-ball, 1. . Surgical Cases and Operations—Encephaloid Mam- Morbus Coxae, 2. Removal of part of lower jaw for * . ~ : - ; * |Exostosis, 1. Bronchocele, 2. Amputation of Fingers, | 1; of Leg, 1; of Arm, 1. Operation for Hemorrhoids, 3; for Anal Fissure, 1. Fracture Inf. Maxilla, 2. Intra- Capsular Fracture Femur, 1. Fracture Tibia, 2. Dis- location Ulna backwards with Fracture Coronoid Pro- cess, 1. Abscess Tibia, 1. Epithelial Grafting, 3. Con- genital Hernia, 1; Scrotal, 2; Irreducible, 2; Inguinal, 1. Lipoma, 1. Operation for Talipes Equinus, 1. En- tero-Vaginal Fistula, (Congenital) 1. Recto-Vaginal Fistula, I. Gunshot wound, Foot, 1. Periostitis Tibiae, 1. Hypertrophy Labia Majora, 1. Hydrocele, 5. Ex- Venereal, etc., Disease.—Syphilis, Primary, 5; Sec- ondary, 10; Tertiary, 6. Orchitis, 2. Lupus, 1. Peri- ostitis, 3. Operation for Urethral Stricture by Ureth- rotome, 3; by Dilatation, 5. Circumcision, 2. Gon- orrhea, 8. Gleet, 3. Sarcocele, 1, Varieocele, 2. In the Pathological Department six autopsies have been held before the class. All the clinical lectures have been abundantly illustrated with specimens. DIVIDED MEDICINES, [he Divided Medicine Com’y, CINCINNATI, OHIO. The Company have the honor of bringing to the notice of the Profession, this NEW AND ExCEEDINGLY PRACTICAL METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. The Divided Medicines are prepared by FREDERICK KRAUS, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUAREs must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MoR.E. . . - The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every square will consequently contain accurately measured quantities. . . . . . . . But not only SoluRIE, but also INSoLUBLE MEDICAMENTs, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINEs. gº Y § This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, ! l * @ & ; , , h, ś, and even idoo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. * * - Besides the peculiarity of THESE MEDICINES, that they are Not LIABLE TO SPOIL BY ANY LENGTH OF TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. - - ... Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calls with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. - - For Samples, Price Lists, and Agencies, address - * - ls. . -- - -- . - . - The lieſne UQ's EOx 2ess, Or FRFDERICK KRAUS, Chemist and Druggist, - Walnut Hills, Cincinnati, O. - MR. FREDERICK KRAUs: * CINCINNAT), l'ebruary 15, 1871. Dear Sir—The specimens of your “ Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: SULPH:MORPHII............~% grain in each square. ARSEN:ACID...... * * * * * * * * * * * * * * * * * * *..l-30 grain in each, square. - “ CHIN.INI ....................... I 4 * { { {{ CALOMEL..............................}4 “ $ $ * { * { 0. COPPER .......................}% . {t 4 \ ºr Respºgtrully Yours, E. S. WAYNE, Analytic Chemist MARVIN's COD LIVEER, CII, * O' D C R LEs s AN ID PALATAB LE. In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERS & BARTLETT, of Portland, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. - Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Serofula, in Rachitic Affections, in Chronic Rheumatism, &c." - - - The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers . of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. - . - We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. . The Messrs. MARVIs, in order to devote their personal attention exclusively to the manufac. ture of the Oil, have retired altogether from its sale, which is in our hands only. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. {? !" |||||||}|| ||||P. ſ 16 × 13.4 S T 34 TH-ST., N E / Yo RK, By Special Appointment Electrical Instrument Makers to the New York State Hospital for Nervous Diseases, MANU FACTU Reſts of PowTABLE ELECTRO-MAGNETIC MACHINES, a - * .." " - - . º - Portable Galvanic Batteries, ('outinuous Current, Stölner's Improved, patented June 1st, 1870, and May 30th, 1871. These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery Fluid. | Mill-III: Millſ; For Iſospitals and General Practitioners, For Bye, Ear, Larynx, Nose, Uterus, Vagina, Bladder, Rec- tum, Feet, Phrenic and Sympathetic Nerves, Elec. trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. EXTRA (Ts rºſto M THE OPINIONS OF THE MOST FIH IN ENT MEMBERS OF THIS PROFESSION. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “Nothing cAN l:XCEED THE EFFICIENCY AND CON V FN (ENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” - We are authorized by Prof. Hammºnd to announce eta- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- provel and re-modified Instruments made by our Company. MEREDITH CLYM ER, M. D., Prof. of Diseases of the Neº- vous System and of the Mind, &c., &c.—“I consider their Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prof. of Surgery, St. Louis:– “In meat- ness, compactness asid efficacy, they can not be excelled.” ALFRED C. GARRATT, M. D., Boston :-"In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” - Similar Testimonials have been received from JOHN J. CRANE, M. D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A. MURRAY, M. D.; CHAS. E. BLUMENTHAL, M. D.; E. C. SEGUIN, M. D.; ALLEN MAYNARD, M. D., Cleveland, 0.; Dr. C. WANNIE, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES KELLY, Florence, O.; Dr. JOHN BECKER, Brighton, Iowa; Dr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes- barre, Pa.; JOHN J. CALDWELL, M. D., Brooklyn, and many other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an Electrical Instrument for medical purposes. CALL OR SEND FOR CIRCULAR AND PRICE LIST. w D E A LE F I N English, French and Scotch {3} { } { } HD's, 34 West Fourth Street, czycz.vx's ra. - * *-*-- - - - - - - - ----------, - - Are furnished to Officers and Soldiers on Govern Irer, tº 8. CCOUlt1t. I claim to have colnbined such improvements in Alt'ſ 1- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Linbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–Why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMES A. EOSTEER, 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cincinnati, Ohio, or 17.2 Jet. ferson Avenue, JPetrºit. $iich, ſº # | jº | 8 º # |; . |#|ºilº injurier; d ºf minuſ;inglli º | H|| ºr-tara º ºse Good sa M.ARIt AN HOSPITAL. The GOOD SAMARITAN HOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner of sixth and Lock streets. It is handsomely furnished through9% and is provided with all the necessary ap- pointments of a First-class Hospital. Porticoes, with commanding views, surround the whole house, and wide hails and abundant windows secure that full and ſtee ventilation which is so essential to health and comfort. Service is furnished by the sist ERs or CHARITY, Under the Superintendence of the well-known sistER ANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. The regular Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each Professor presiding over his own especial department. Patients may, however, select from the regular profession of the city any physician of their choice. The (;OOD SAMARITAN HOSPITAL presents extra inducements to Invalids throughout the State as a safe and quiet asylum in any case of protracted illness, ºr in cases, more particularly, requiring Surgical Operation, where some stay is necessary in after treatment. * Rooms vary in price, according to the ºutructer of appointments necessary and service required, ranging, iº general terms, between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand of gºş Address, th SISTER ANTHON.Y, Hospital of the Good Samaritan, Corner of Siacth and Lock Sts., Cincinnaté. Ohio, 3. - - * * ". * : - * . * ºr sº - - - - r ..: ' ' - - * Is Now READY FORCA NvAssFRs. It contains over 600 pages of reading matter, with 250 engravings, designed expressly for this work, by the best artists in the country. Agents now at work upon, it are meeting with unparalleled success. Agents at Circleville, . . . O., reports 25 orders in, 2 days; one at Louisville, Ky., . . reports 175 orders in 8 days; one at Middletown, Conn., | : ------- ~~... •...vº --- CAMARGO MANUFACTURING COMPANY. MANUFACTUREIts AND IMPORTERs of reports 200 orders, in 12 days; one at Cincinnati, O., re: jºi ... ' ports 250 in 12 days. Early applicants secure territory. For circulars; terms, &c., address …” 101 Elm street, cineinnati, o, ‘. . . . . ... º. . . 9, . . - a- * . . . . . . . ." , ; * x * ºrna - i.e. z. r - - - - * : * - r º - - - ... ſº ſº ºff; * * * * * , } 7%g (ºf * ſº." Aºi * ſº tº Hº). º »). * ºf -º-, --, --- sº sº. --, *s Blank Book Manufacturers, 1:so v1N -ris Exºr, | sº sº. T. D. A. LBRO & BRO. 1 M.Põ R'l'F.RS AND MANUFACTURERs OF FOREIGN and DOMESTIC WOODS In Veneers, Boards and Plank, intãº-Mºº-Biºaiti-kiºi. The only. lieuse in the western country that saws Spanish and Mexi: ran Cedar for Cigar-Box Makers We import our own wood direct, and "" in sell at prices to compete with any and everybody. Also saw and keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. Office and Warerooms, 136 and 138 west second street, Wenzer Milº. 507, 509, 541, 513 & 515 W. Sixth St., CINCINNATI. 32 West Fovara screer, CISC(NSXTI, (). H. H. BRENEMAN, Proprietor, R FO R GENTLEMEN. Handling much larger quantities of fine and valuable Underwear than any other firm in the West, we are enabled to purchase at closer fig- ures. We are therefore prepared to ofter extra inducements to consumers. HO's HR CRY, FULL LINES OF THE BEST ALWAYS ON HAND.. SHIRTS MADE TO ORDER. wilson BROS, Pike's opera House, Cincinnati: 981 Wabash Awe- atue, and SS West Washington street. Chieing is. º ** * | , iſ .* vs vs º - º w a . º, º |º sº- E. Tºº : ºf it tº º . . . .Hiſ - . . f * * * -- * W. * :-. § AN, K. º & ſº § º . || . . . it’ - ----- º Hjºiºſº . ." §§§ º * --...-. t * Zºš, Ss º: º re- v ºf ; ; ºr. - ! ..." U || || * - * . ...” ſ º E- l #--- - -§: wº- w: { CINCINNATI. ROBERTS BARTHOLOW, M.D., º it. º i sº w | º: - a - -. ſº | | | | | | | | | || -º-º-º-º-º-º- * ------.p. - **- • FA C U L T Y. - . . . . J AM ES G R A H A M, M. D., DEAN, Professor of the Theory and Practice of Medicine and Clinical Medicine. Professor of Materia Medica and Therapeutics. W. H. GOBRECEIT, M.D., Professor of Anatomy. P. S. CONNER, M.D., Professor of Surgical Anatomy. W. W. SEELY, M.D., Professor of Diseases of the Eye and Ea SAMUEL NICKLES, M.D., Professor of Physics and Medical Chemist .J. A. N4. IC S ~ --- T. LOUIS BROWN, Prosector of Anatomy. -*-*------------------------------------ 7". ry " I " . W. W. DAWSON, M.D., Professor of Principles and Practice of Surgery and Clinical Surgery C. D. PALMER, M.D., . Professor of Medical and Surgical Diseases of Women. T. A. REAMY, M.D., Professor of Obstetrics and Diseases of Children. JOHN L. CLEVELAND, M.D., Demonstrator of Anatomy. CHARLES KEARNS, M.D., Assistant to the Chair of Surgery. VV H. I. T. "J. A. LX R. J.R. . I” “) ſº “so I of JP) ysiology &nd Secretary of tin & Rºc 1 ty. Janitor, College Building, Sirth S., bel. Vine and Race. Pym'ed and Published by Noit Riº & M Unity, Medical College of Ohio Building, Cincinnati, PUBLISHED EVERY SATURDAY. If M S-$2.00 a Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editor: , . . . “All Communications relating to Business, Subscriptions, Adyertisements, etc., to the Treasurer. < Vol. 2. C IN C IN N AT I, J A N U A R Y 27, 1872. No. 4. JAS. T. whittaker, M. D. - - - Editor. No. 101 West Ninth Street, Cincinnati. -A-SSO’CIA-ºri; Eºdrº CER.S. W. W. D.Awson, M. D. ... Thad. A. ReAMy, M. D. P. S. Conn ER, M. D. C. D. PALMER, M. D. W. W. SEELY, M. D. SAMUEL Nickles, M. D. CHAs. KEARNs, M. D. - Rod ERTs BARTHollow, M. D. W. W. SEELY, M. D., TREAsukes, No. 118 West Seventh street, Cincinnati. : -y- club RATEs. 4 Copiés to ône address. JNo. L. CLEvel,AND, M.-D. Fashionable Hatters, - 1uPontens AND MANUFACTURElis of "EAnths' rugs, * * |92 wrisT FOURTH ST. Opposite Post Office, CINCINNAT). sarspeeial inducements to Medical Men. • * #. .*. ** is sess sº $ 7.00 6 & & & & -- 10,00 12 44 “. ...... * 18.00 C O N T E N T S. * } -: Tage * 3. origiNAL.ARTICLEs. º Intestinal Invagination; by Jasºr, whittaker, M. *~~~~~gº Rupture of the bladder, by P. Gardner, M.D ...” Fistula for Cystitis, a Reply to a New Critic, by A. T. Keyt, M. D....40 Translation Still Birth, An Abstract of a Review of Schultze’s Treatise (from the Archiv f. Gynaecologie, Vol. II. Sect. 3, 1871.)........................ 43 screNTIFIC NoTEs. Influence of Light on Sugar—Diabetes and the Fourth Wentricle of T-e-s-s-s-s-s-s s KoºBI. *Till.Man i - Bºś AS § NGRAVER -Sºlº WEST FOURTH SH sº SoNYWOOD US CINCINNATI. Oiſo, * * * * * * J. TAFT, W. TAFT. Editor Dental Register I. A w. Tart. IDENTIsTs 117 WEST FOURTH STREET, ~ - , - CINCINNATI, O. the Brain 43 MEDICAL NEWs Med. Service in the Navy—The Pest in Persia—Honors Recipro- cated—Small-Pox in Germany.................................. * * * * * * * * * * * *44-45 COLR RESPON D, ENCE Letter from Dr. Trush, Vienna, on Vaccination—Letter from Dr. Whiting, Another Misinterpretation....... 45-46 CLINICAL MEMORANDA Removal of Morbid Growths in Larynx by Section of the Cartilages —Bullet Explorers—Iodides of Ammonium and Sodium in Syphilis 46–48 48 The Spring Course of 1872 *-* * * = <= * = a- = Now is the time to subscribe for THE CLINIC. The new Volume is just commencing. Over 150 new subscribers are already entered this month. Back numbers are dis- appearing fast. . the pental R egister, A Monthly Journal, CONTAINING 48 PAGES, Devoted to the Interests of the Dental Profession, ROBT CLARKE & Co. William Autenrieth, PUBLISHERS, }|||}|S&Willº N0, 65 WEST FOURTH STREET, * Call the attention of the Medical Profession to their Extensive Stock of &nglish, 3merican and freuth JMAEA/CºA, AE(90AES, Paying particular attention to this branch of their business, they are enabled to execute all orders on the shortest notice, and at the most reasonable rates. Their facilities for the impor- tation of FOREIGN BOOKS, THE PROCEED- INGS OF SOCIETIES and HOSPITAL RE- PORTS are unsurpassed, and any orders en- trusted to their care will be filled promptly, and at the lowest rates. Subscriptions received for FOREIGN and AMERICAN PERIOD1CALS. All the New Publications received as soon as issued. Letters of Inquiry will receive our prompt and full attention. Catalogues furnished gratis on application. ROBERT CLARKE & Co., Whilºlºmºnºliº PRINTERS AND BLANK BOOK MANUFACTURERS, 22eaders in Zazy, Medica?, Z/ºeočoytcal, School, azed./esce//azzeozºs Zºoo/s, Q55 West Fourth Street, CINCINNATI, O. No. 71 WEST SIXTH STREET, BKTWEEN WALAUT-Aîb WINE, CINCINNATi, OHO, MANUFACTURER OF AND DEALER IN |||}|| || || || ||||||||} Abdominal Supporters, Trusses, GLUB-F00T SHOES, SPINAL APPARATUS, ETſ Koeps constantly on hand a full variety of Metalic and Eubber syringes, Stomach Pumps, Etc. STOCKINGS FOR WARDCQSE WEBNS, Special attention given to the fitting of Apparatus for Deformities. B& Agent for DR. L. A. BABCOCK'S Silver Uterine Supporter, -AIMSO- DR. AHL's POROUS FELT SPLINTS, -ALSO- T) A. Y. * S S B L T N T S -AND- S. W. Elliott’s Saddle-bags List of Pharmaceutical Preparations, worry wreza e amozwan, PHILADELPHIA ELIX, PHOS, IRON, QUININE AND STRYCHNIA, - . . . . . ELIXIR OF GENTIAN FERRATED, ELIXIR WALERIANATE OF AMMONIA, - - (Goddard's Formula,) * ELIXIR VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSFHATE OF IRON, Iron, with Phiosphorous and Calisaya, FERRATED ELIXIE OF CINCHONA, Iron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK, ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, CCMFCUND SyFUP OF HYPOPHOSPHITES, . . ~ * COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Coimposed of the Phosphates of Lime, Soda, Potassa and Iron,. BITTER WINE OF IRON, citrate of Iron and Peruvian Bark, - FERRATED CORDIAL ELIXIR, ELIXIR CALISAYA BARK, WINE AND BISMUTH, ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, wiNE OF WILD CHERRY BARK, . . . . . FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, - - ºf . . . . . . TASTELESS COD LIVER OIL, TASTELESS COD LIVER OIL. FERRATED, - ... . . . . . . . . . . BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and sherry wine, ELIXIRVALERIANATE OF STRYCHNIA, WINE OF PEPSIN SYRUPSUPERPHOSPHATE OF IRON, ----, & . . . . . . . . . . . ___ ELIXIR OF BISMUTH, COMP. FLUIDEXT, BUCHU AND PAREIRABRAVA. stſ PPOs.ITORIEs. Rectum, Vaginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great care, and of every variety of combination. Lists sent on application. - SPÖ NGE TENTS:—For the Urethra, of every size and 8tyle, made of fines; quality of sponge. Wm. Wilson McGrew, JW2, 9% WESZ" Aſozºzºz Szºzº, PIKE'S OPERA HOUSE BUILDING, Ap Importer and Dealer Diamond and Gold Jewelry, Watches for Ladies and Gentlemen, Sterling Silver Tableware, Bronzes, Antique and Modern; Marble and Bronze Clocks, Marble Statuary, FAN cºr Coons, GENER ALLY. IMAIRVIN'S cold LIVEER, OIL O ID O IR. I L I FC S S A. IN ID IPA. L. A. T. A. IB L E • In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERS & BARTLETT, of Portland, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits" which should gain it the preference over any other Oil in the market. Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachitic Affections, in Chronic Rhewmatism, &c. The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. DIVIDED MEDICINES, PREPARED BY The Divided Medicine Comy, CINCINNATI, OHIO. $ The Company have the honor of bringing to the notice of the Profession, this NEW AND ExcEEDINGLY PRACTICAL METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. The Divided Medicines aré prepared by FREDERICK KRAUS, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MORE. The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every square will consequently contain accurately measured quantities. But not only SoluRLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINES. This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, ; : *, *, *, and even 10bo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. Besides the peculiarity of THESE MEDICINES, that they are NOT liablE TO SPOIL BY ANY LENGTH OF TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calis with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. For samples, Price Lists, and Agencies, address The dicine CQs, IECX 2688, Or FRFDERICK KRAUS, Chemist and Druggist, Walnut Hills, Cincinnati, O. MR. FREDERICK KRAUs: CINCINNATI, February 15, 1871. Dear Sir—The specimens of your “Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: 8ULPH:MO RPPIII....................... % grain in each square. ARSEN: A CID.......................... 1-20 grain in each square. tº ſº CIT IN.INI ....................... 1 § { § { { % CALOMEL.............................. % 6 & 6 & * { “. COPPEſt ........................}% dº RespecTFULLY YoURs, E. S. WAYNE, Analytic Chemist. JAN, 27, 1872.] O R. I. G. I N A L A R T I C L E S. : O : I N T E S T IN A IL IN V A G IN A TI O N . BY JAS. T. WHITTAKER, M. D. Abstract of a Lecture delivered at the Good Samaritan Hospital, Jan. 13, 1872. GENTLEMEN : We are doubly fortunate to-day in the specimen to form the subject of our study: first in that it is in some respects one of the most remarkable examples of a very rare lesion in pathology; second in that it concerns a part of the body whose physiology is still fresh in our minds. It is really a subject of mutual congratulation that so many choice specimens in pathology have pre- sented in the limited time allotted to this department of our science; indeed, such good fortune had not been ours were it not for the occasional assistance of distant friends. I mention this fact merely to acquaint you with our obligations to Dr. Shackleton for the rare consideration he has exhibited to all of us in placing this specimen with the following letter in our hands. ST. MARYs, OHIO, Jan. 8, '72. Dear Dr. I send you this morning by express a specimen of invaginated bowel; it will perhaps be of some interest to you and the class. The man from whom the speci- men was taken was treated by my friend Dr. Stearns, of this place. The autopsy was made this P. M., 22 hours after death by Drs. Stearns, Bradley and myself. I will give you the history of the case as nearly as I can. The man was 51 years of age. The friends say he has suffered since boyhood with “cramp colic,” for the past twenty years he has suffered very considerably, and has during this time firmly believed there was a reptile of some kind in his bowels. This idea of his has ex- cited the curiosity of the whole country. In the inter- vals between his attacks of colic he lived with a con- siderable degree of comfort, indeed, was able to work hard. He has always been troubled with constipation and for many years there has been a very great amount of gurgling, peculiar and loud in the right iliac region; this gurgling was always exceedingly annoying to him. His last illness was of about a week's duration; during this illness there were unmistakable evidences of peri- itOnitis. * We found the abdomen very tympanitic, large quan- tities of lymph thrown out over the peritoneal surface, the whole bowels largely dilated; old adhesions over T IEEE TEE C T I I INT I C . 87 all parts of the intestines, stomach adherent to liver and small intestines; right kidney so adherent to intestines that on removing the bowels the kidney was torn out with them. General adhesions were so numerous that it was very difficult to trace up the small intestines. In moving the coecum we would get the characteristic gurgling Sound that was so noticeable during life. You will observe two outgrowths from the mucous surface, what are these ? Let us have the benefit of your exam- ination. Part of the receiving portion of the bowel you will perceive we cut away, an unavoidable mutilation, which I know you will regret. Yours Truly, E. Z. SHACKLETON. The most striking conditions manifest in this C3Sé a re first, the immense size of the gut. The largest German Sausage, the Schinkenwurst, may hardly aspire to such dimension as this. It measures in circumference 13 inches. If all the invagination has been removed, about 12 inches of the ileum has slipped into the colon. Next you will observe its marked discoloration, where it is not absolutely black, it is deeply livid, only here and there is the hue of a lighter red, nowhere of the normal clear and shiny gray, It has lain in alcohol on its way down to us consequently the odor of the decomposition so evidently present is no longer perceptible. To the touch it is resistent with a distinct doughy feel. At one extremity just above the coecum, which we recognize by its blind extremity, there is a protrusion of intestine through a button-like orifice. This is plainly the divided Small intestine as it enters the ileo-coecal valve. We have then before us a case of intussusception or in- vagination, volvulus it is sometimes improperly called, of the small intestine in the large. The ileum to use a rough illustration, is “telescoped” into the colon—and caught there and held by firm adhesions, between the apposing surfaces. Singular are the anatomical rela- tions of these surfaces. If I take this piece of healthy intestine and push one part down into the part below it, ensheath it, in other words, or invaginate it—vagina means a sheath—you will understand how it is that peritoneal surfaces and mucous surfaces must always come in contact with each other. If I now cut across the gut as ensheathed I expose three circles all round its circumference. The outermost is the receiving or intussuscipient gut, the innermost is the received or intussuscepted gut and the middle is the receding por- tion connecting the two. . What is the most remarkable feature of the case before us is the enormous thickening that has occurred in the inflammatory processes which have united the invaginated and receding layers. As you observe the combined wall of these two layers is quite three inches thick. This it is which has narrowed down the calibre of the received or interior gut so that I can barely insert into it the end of the little finger. Of course the mesen- 38 [JAN, 27, 1872. T H. H. cI.TISTI c. tery of the ileum must have been dragged into the large intestine, but it was doubtless removed in the difficult operation of dissecting out the large intestine. It is because the mesentery of the ensheathed is dragged into the ensheathing intestine that these inflammatory processes are first engendered. The mesentery carries the blood supply; the intestine, in some cases entirely deprived of its blood, undergoes necrosis and death, a condition which we have learned to regard as a conserv- ative process of nature. • . The reason of this rare accident is difficult to under- stand. When there is no tumor present whose weight might have dragged down the upper portion—and all the invaginations described are in the line of peristalsis —or no foreign body impacted which may have acted in the same way, we must assume a paralysis of the lower portion of the intestine whereby it is left dilated after the part above it has contracted. What would tend to support this view is the fact that every increase of the original invagination is at the expense of the re- ceiving part of the tube. Pflüger has shown experi- mentally that an irritation of the splanchnic nerves does hem the action of the intestinal muscles. Once produced, there is of course a constant tendency to its increase upon every contraction of the receiving part of the intestine. This accident may occur anywhere in the intestimal tract, small or large, most frequently, however, is it en- countered in the large intestine particularly at the ileo- cCecal valve as in the case before us. - In most cases as may be readily understood it termin- ates in death, either by the peritonitis excited or by septicæmia from the absorption of putrid matters. Yet cases of favorable termination are not So Very rare. Either the invaginated intestine, then, sloughs off and is passed per anum leaving a thick fibrinous ring at the point of entrance, or it becomes firmly adherent to the receiving tube leaving its calibre open. Sometimes it sloughs but partially, then there depends at the lower portion a fringe-like mass of mucous membrane, thicken- ed and engorged as in the present case to resemble neoplasms on the inner surface. In the first two cases recovery may be perfect. In the last there is constant intestinal difficulty left. It is easy enough to understand how cramp colic and constipation were constant attendants upon this case. The constriction of the inner tube is so great, indeed, that is wonderful that stercoraceous vomiting was not a symptom in his history. Evidently the canal was large enough to permit the passage of feces to extent sufficient to prevent this complication. The amount of thickening here, the really immense quantity of exudative material present, clearly proves the chronicity of the affection. In all likelihood this condition has existed ever since childhood, of course in much less marked degree. In course of time the tube became narrower and narrower, fecal accumulation with corresponding gaseous formation, as evidenced by gurg- ling and tympanites, more and more marked, the local became very gradually a general peritonitis, the cause of the death which was the only relief possible to such 3. CàSG. * The following cases collected from different sources at hand illustrate the different varieties of this lesion with other points of interest connected with the subject. 1.—Intussusception of portion of ileum. Passage of intussuscepted part per anum. Recovery. Woodman, Times and Gaz., Dec. 3, 1870. Temale, aged 41. At- tacked with sudden violent abdominal pain and vomit- ing. Pain localized at regio hypochond; no tumor palpable; constipation two days. Thirteenth day pains much more violent; spontaneous evacuation with piece intestine belonging to ileum. Recovery in short time. 2.—Extensive invagination, Small and large intestine. Ballard, Transact. Path. Soc. Lond, vol. viii, p. 385, in a child 6 mos. Death 6th day. Part of ileum and upper part of colon found in descending colon. Volvulus palpable, per rectum, to finger, like pregnant OS uteri. 3.—External protrusion, Sydney Jones, Transact. Path. Soc., loc. cit., p. 179. Healthy child at breast, sudden vomiting mucus and blood, constipation. End 3d day fecal discharge, recovery. Recurrence symp- toms after 3 weeks, stools with difficulty, End 4th week bowel gradually protruded from rectum to length of 6 inches. Gangrene ensued, death 9 weeks. Lower part of ileum and coecum with appendix found invag- inated into colon. Tube narrowed to # inch. 4.—Intussuscept, flex. Sigmoid, coli and upper part rectum. Holmes, Transact, l.c., p. 177. Tailor, aged 40. Diarrhea alternating with constipation. Death. End of invagination, which was 3 inches long, fringed. Perforation upper portion, communicating with Douglas space. 's - 5.—Invaginat, one yard Small intestine in consequence of fibrous tumor, size of a Walnut, Springing from mes- entery. Knauss, Würt Corr. Bl. 28, 1859, from Schmidt's Jahrbücher. 6.—Invag. and discharge after gangrene of nearly one yard of intestine; 10 in. ileum, whole coecum and part of colon ascendens. Perfect recovery in 14 days. Voss, Norsk Magazin vii, 1858, Schmidt’s Jahrb. cv, 335. 7.—Invaginat. descending colon, child, repeated hem- orrhage, Jacobi, Schmidt’s Jahrb. cxii, p. 362. 8.—Invag, one foot small intestine in colon after in- gestion one pound of cherries with seeds. Blandlot, Gaz Med. de Paris. Countryman, aged 19. Intense pain, obstimate constipation, death. No adhesions, canal size of little finger. 9.—Invaginat. Small intestine and coecum. Grizolle, Session Anatom. Soc., Paris. Schmidt's Jahrb., vii, 248. Diarrhea a constant symptom in life. Death by peri- tonitis. - 10.-Invag. colon in rectum. Lond. Med. Gaz., XY, Oct. 25, 1834, from Schmidt’s Jahrb., vol. vii, p. 282. Coecum and colon both invaginated, 10 mos. child. Only with considerable difficulty could the invagination be withdrawn. JAN, 27, 1872.] T TEEE THE C T , T N T C - 39 11–Invag. large part small intestine complicated with ascites. Schmidt's Jahrb. II. p. 40, 20 cent. ileum, coecum and ascending colon invaginated into sigmoid flexure and rectum. 12.-Invag. caused by traction fibrous tumor in mu- cous membrane. Holmes Surgery, iv, p. 612. 18.-Invag. 8 in. ileum with coecum and appen- dix. Recovery 6 weeks, Holmes Surgery, l.c. p. 617. 14—Invag. and discharge 29 inches colon in child 6 years of age. Gross Surgery II. 617. This is the cel- ebrated Dawson case. Notwithstanding the immense loss of intestine the child made an excellent recovery. From the same work is quoted the following “In 35 cases analyzed by Dr. William Thompson, the invagi- nated pieces varied in length from six inches to three feet and nearly all included the entire cylinder of the tube along with a portion of the mesentery. The small bowel was concerned in 22 cases and the large or the large and small in 13. The average duration of the disease was from four to five weeks.” REMARKS.—The rarity of this affection is illustrated by the fact quoted in Holmes Surgery that in 48,218 children [in whom invagination is most frequent] treat- ed at the Hosp. for Sick Children, London, in five years, but one death from invaginated intestine oc- curred. In the treatment of acute cases it is proposed to un- fold the invagination before adhesion has occurred by the injection of air or water. But little success, however, has been obtained in this way. A case is reported by Dr. Baldwin, of Florida, Am. Journ. Med. Sci., Oct., 1852, p. 568, where a supposed invagination was relieved by the injection, per rectum, of a large quantity of air. Pirigoff, according to Henoch. Klinik der Unterleibs Kr. Berlin, 1858, first proposed the operation of entero- tomy, laparotomy or entero-laparotomy, in relief of recent cases. According to Ulmer (loc. cit.), laparotomy has been undertaken in 11 cases of intestinal obstruc- tion. The operation was successful in six of these. It is alleged to be no more dangerous than caesarian sec- tion, lithotomy, extirpation of uterus or ovariotomy. Knives, forks, and other foreign bodies have been re- moved by laparo-enterotomy by Schwabe, Renault, Gruger, Shoval, Frizac. The operation has been repeat- edly performed as a means of prolonging life in oesoph- ageal stricture. The difficulty of locating the lesion is Principally theoretical. In most cases a tumor is palpa- ble. If not, the section should be made so as to reach the coecum where invagination is most frequent. After section the lividity of the intestine reveals the seat of the disease. The occurrence of stercoraceous vomiting is a safe indication of the time for operation. This usu- ally occurs from the 6th–9th day. Pfeiffer even went So far as to claim that “Laparotomia est volvulo neces- *ia.” Maissoneuve concluded his celebrated speech at the Paris Academy on this subject as follows:– “Intes. tinal obstruëtion, differ as they do in their nature, are **ide of the limits of our art. The chief means of relief is laparo-enterotomy. This operation may be at- tempted with hope of success in all cases where no gen- eral peritonitis or gangrene is present.” Finally, he cites the successful case of Dr. Reali in the hospital at Orvieto—Fror. Not. No. 182, May, 1849. The great relief of the terrible pain of gaseous disten- tion by puncture of the intestine is alluded to by sev- eral authors. In the treatment of chronic cases where adhesion and possibly gangrene has supervened, is there no hope left. In a case of this kind where there is such general ad- hesion that the right kidney was torn out in the act of dissecting away the invaginated gut there is of course no relief but death. But if the adhesions be not so great as in the present instance—and I find no case where they were so universal—would it not be justifia- ble to exsect the whole affected tract of intestine and unite the divided ends? Certainly we know that when a very great portion of intestine naturally sloughs away complete recovery follows and as well we know that several feet of intestine may be excised in the lower animal and the divided ends united by suture without the least, other than temporary, inconvenience to the animal. —º-G-sº- Accidental Rupture of the Bladder. BY P. GARDNER, M. D. Pine Grove, Ohio, On the evening of the 16th of November I was called to see Mr. W. R., at. 28, of mixed temperament, nervous predominating. On my arrival I found him in a most helpless and pitiable condition. His story was as follows: “About 1 o'clock P. M., of that day he had mounted a hay stack, leaving the pitch fork behind ; from some cause his foot-hold gave way and he slid down to the bulge of the stack where he encountered the upper end of the fork handle which struck him in the perineum” just anterior to the border of the sphincter, lacerating the parts extensively, entering the pelvic canal, ruptur- ing the bladder above its neck, passing backward pene- trating the rectum and ascending as high as the pro- montory of the sacrum. Here he was pinned until an assistant came and withdrew the fork by force. The bladder being distended at the time of the accident its contents were discharged into the open wound and escaped externally. I introduced a catheter through the urethra and threw an injection through it into the bladder; the injection was immediately thrown out through the accidental opening. I resolved, then, at once to avail myself of the benefits of the tube used after lithotomy, and requested medical assistance in the case. In due time Drs. C. D. Wall and W. W. Mills arrived, the former administered chloroform while the 40 [JAN. 27, 1872. T TEI IEH C T I I INTIC . latter aided me in introducing the tube through the wound into the bladder. The task was somewhat difficult but we at length succeeded, and in a few min- utes the urine commenced passing through the tube. I may here state that I evacuated the bowels freely before introducing the tube,and found that the opening in the bladder and rectum communicated, and that the faeces passed directly into the bladder. After the intro- duction of the tube I administered tannin and opium freely, and kept the bowels confined for six days, and thus obviated that difficulty. I allowed the tube to remain in the wound until the eighth day when I intro- duced the catheter through the urethra and withdrew the tube, plugging up the opening with lint saturated in glycerine. Occasionally air found its way into the bladder for a few days but I allowed the catheter to remain until he could micturate easily then withdrew it and a speedy recovery followed. In fifty days after the receipt of the injury he was able to go around and is now able to attend his business, suffering no incon- venience from the injury. Such are the facts without note or comment which I respectfully submit to the profession. ———sº- ©-sº-----— A Vindication of a Criticism on Fistula for Cystitis. BY A. T. KEYT, M. D. Being a Reply to Dr. Emmet.* In The Clinic of December 30, is a communication from Dr. Emmet in defense of the treatment of chronic cystitis by vesico-vaginal fistula; avowedly called forth by criticisms on this practice, one by myself, and one by an anonymous correspondent, both published in The Clinic of November 18. This communication with all kindness and respect towards the distinguished and gentlemanly author, I beg leave to notice. Says Dr. Emmet, “It is evident that the objections made to the operation, although plausibly taken, are merely theoret- ical.” Evidently the intention of this allegation is to destroy the force of the objections. My object was to produce such an invºntory of evils pertaining to this procedure as would present it in the light of its gravity. These conditions were so plain to my mind, that I had no thought but that as named they would be accepted. As they are now challenged in high quarters, it becomes eminently proper to briefly, as may be, examine the grounds on which they stand. I said the operation was very painful. It is a law well recognized, that a wound inflicted upon a sensitive part of the body will cause a sensation of pain. Under * Dr. Keyt is justly entitled, as he claims, to reply to a new critic. With this reply the discussion of this subject in The Clinic is definitely concluded.-EDS, CLINIO. this general law then, I cannot err in affirming as very painful the operation of thrusting a trocar through the sensitive vesical and vaginal walls, and the extension of the wound thus made by Scissors. Of the dangers of the operation, I instanced: 1st. Hemorrhage. This danger is deduced from ; first, the general law, that incised wounds of vascular parts are followed by bleeding: secondly, that this is an in- cised wound made in very vascular parts: thirdly, the inevitable therefore of the syllogism: fourthly, the fre- quency of this occurrence after lithotomy operations, so analogous to this: and fifthly, the difficulty of arrest- ing the hemorrhage, in this situation. If these prem- ises are good, the conclusion is just. This is a real danger not to be diminished or ignored by pronouncing it “merely theoretical.” 2nd. Shock. It is a perfectly rational conclusion, from what we know of the effects of wounds upon the nervous and vascular systems, and especially of the effects of op- erations on the bladder, that this condition would be an element of danger. It is produced for just what it is worth and no more. The inference is, that the lesser f rms of nervous disturbance, as rigors, etc., would be quite frequent, and the graver forms constituting shock proper, not so remote as to be justly omitted in an estimate of the gravity of this operation. 3rd. Urinary Infiltration. This condition is appre- hended from the situation being favorable for its occur- rence, and from its known frequency after lithotomy, which in vaginal lithotomy presents the same conditions, and in the male, conditions sufficiently analogous for just deduction. - Here are the walls of the bladder and vagina with a layer of loose connective tissue between them. A wound is made through and through which of course opens up this tissue. The urine trickles along the channel of the wound, and as it does so, a portion settles into the meshes thus ready prepared for it; then by gravity it sinks to and permeates the cellular tissue of the lower portions of the pelvis, and plausibly, by the operation of capillarity and the law of the diffusion of liquids it rises higher, and is more extensively and thor- oughly diffused. If there be a question as to the operation of these last two agencies, there can be none as to that of the first under whose influence alone sufficient region is invaded for most serious and ex- tensive ravages. ' The situation as it exists is thus seen to be favorable; nor is it essential as stated by Dr. Emmet, that there should be an “accumulation in the bladder;” though in the probable event of a temporary obstruction in the vaginal portion of the wound, the vesical portion remaining open, the opportunity of infil- tration would be increased; for then a collection of urine in the wound would be in steady contact with a larger surface of cellular tissue, thus favoring a more rapid diffusion; nor indeed is it at all presumable, that the tube with its vesical button, if one be used, can so accurately fit all the parts as to draw off all the urine. JAN, 27, 1872.] TIH. H. C. T.I.N.I. c. 41 I have been thus particular in the elucidation of this point because I have evidently been misunderstood. I hope now my meaning is made plain. Again, urinary infiltration is apprehended after this operation because it is a mostgrave and common sequence of lithotomy. Erichsen, in his surgery, states, “diffuse inflammation of the cellular tissue of the pelvis—is the most frequent cause of death after lithotomy.” And “the urine, as it escapes through the wound, sinks into the meshes of the loose cellular tissue over which it flows, and thus gives rise to infiltration, followed by rapidly extending inflammation and sloughing which speedily involves the whole of the neighboring textures.” When authority so high speaks so well it is needless to deduce other. If infiltration then takes place so readily after lithotomy, it can readily take place after this op- eration in which similar conditions and relations of wound and cellular tissue exist. It will also be noticed, that Mr. Erichsen’s idea is that the urine sinks into the cellular tissue as it flows through the wound, and not that it is forced in by a distended bladder behind an ob- structed outlet. 4th. Inflammation and ulceration of the wound. The wound thus made with its surfaces separated and bathed in urine, and the contiguons cellular tissue infiltrated with urine, must inflame and ulcerate. It is a natural and inevitable inference that in some cases the action would prove excessive, and result in sloughing of the wound with the evils of this process—among which may be mentioned a liability to secondary hemorrhage. This fourth danger can likewise be well supported by appealing to the results of lithotomy. 5th. Pelvic Cellulitis with its train. If the liability to infiltration of urine is established, this condition as surely follows, and it is even more certain, because it may-arise, also, from inflammation extending along the connective tissue from the wound as a starting point. It is needless to make any presentation of the well known gravity of this evil with its abscesses, sloughing of tissues, pyemia, etc., etc. 6th. Peritomitis. This grave element of danger arises in the same connections as the last. These, then, are my objections to the primary opera- tion with the reasons so far sustaining them. One species of argument I well know has not been introduced: I have offered no facts, no cases in which these evils and dangers were actual occurrences. As yet, we have had no full reports of cases subjected to the operation, and so we are in ignorance as to what facts they contain. If nothing to our purpose can be derived from these, we gravely apprehend the future will furnish all the facts needed, if gentlemen continue to perform the operation and give full reports of their cases. Even in the pres- ent showing of a limited number of cases where it has been performed, as claimed, without serious complication or disaster there is nothing to weigh against the conclusion of rational deduction, that this is a dangerous operation. When by sound reasoning a priori a procedure is made out as hazardous it is not logical or safe to disregard the conclusion, though the results of experience should be for a time against it. Some illustrations of this propos- ition arise in my mind which I proceed to give. Some years ago, when chloroform was being intro- duced as an anaesthetic, men reasoned about it, and con- cluded it was unsafe. They felt quite sure that an agent capable of such sudden, and powerful and pro- found influence would sometimes prove fatal, others were using it with happy effect; and reasoning from their experience it was safe. But what of chloroform to-day ? Let the published records of “deaths from chloroform” answer The structures, forces, and actions concerned in the process of parturition are such as to suggest in connec- tion with it the liability to uterine hemorrhage; and yet, in my midwifery practice, there have been times when I have had such a succession of cases in which “the loss of blood was so trifling as to be of no conse- quence,” that I might have concluded from the results of my experience, that the fear of hemorrhage in these cases was entirely theoretical. I extended my expe- rience, and met with the fearful floodings. Conceive of one reasoning, without reference to results, about the Safety or danger of lithotomy. By a natural and easy process he would arrive at the conclusion that it would be a highly dangerous operation; and yet, in the experience of many surgeons, this fatal operation has been performed, for a time, in an unbroken line of SUICCéSS. “The late Mr. Lynn had cut 25 patients with- out losing one, and he said that he thought he had at last discovered the secret of performing lithotomy with success; but, he added, that the Almighty punished him for his presumption, for he lost the next four cases that hg, cut.” “Mr. Liston, during a period of six years, in which he operated twenty-four times, lost no patient from litho- tomy at University College Hospital; but out of the whole thirty-seven cases which he cut during the period of his connection with that institution, there were five deaths; reducing the average to 1 in 7.2.” And the operation, now on its trial, so manifestly dangerous, from the possession of intrinsic and significant elements of danger; from its being so closely allied in the character and relations of its wound to lithotomy; and hence partaking to that extent of the evils and fatality of that operation; and again, from its being performed on patients broken down, without recupera- tive eſtergy, and hence more liable to suffer the evil consequences dreaded : even this operation has been performed a number of times without, it appears, re- ported disaster; and on the strength of these results it is declared by Dr. Emmet, its great American Exponent, “attended with as little risk as any operation in minor surgery.” If experience is extended, in this direction, we look to future tables with a column showing the number of cases operated on, and another the number 42 [JAN. 27, 1872. T H E c T.I.N.I. c. of deaths, to prove the fallacy of this limited experience, and confirm the conclusion arrived at by sound reason, that this is a dangerous operation. But the evils of the method, unless in the event of the patient's death, extend beyond the first operation. Upon the evil of the continuous dribbling of urine, I need not dwell; for Dr. Emmet states:— “The only serious objection to the operation is the inconvenience to the female from the escape of urine.” In my first communication I offered as objections the 8wbsequent operations. It is plain that two conditions of the opening may exist; first, a contracted condition with tendency to closure following a minimum of in- flammatory and ulcerative changes in the wound; and secondly, a permanently patulous condition following more or less sloughing of the wound. Evidently, if, in the contracted aperture, a tube with a “button” were retained, it would be so embraced as to necessitate an operation for its removal. If the tube be not worn or other means of maintaining the opening employed—and the frequent introduction of tent or bougie would be another evil—the fistula closes prematurely and all that was sought is lost. The plan must then be abandoned or the patient subjected to another operation. In the other condition of permanently patulous opening, the patient will ultimately require the operation for vesico- vaginal fistula or be left to go through life with her dis- tressing infirmity. This operation may indeed be “so well known and simplified in its every step, as to be within the scope of many surgeons all over the country.” Nevertheless it is equally well known by many surgeons and by all intelligent physicians, as well as keenly by the unhappy subjects of it, that it is an operation very tedious, very distressing, of considerable difficulty, often extensive and very liable to failure. It is well known, too, that the after treatment compelling con- finement to bed in a constrained and fixed posture with a catheter retained in the bladder and the bowels kept constipated by opiates, is exceedingly irksome and dis- tressing to the patient. The operation, too, has its risk, though in a just estimate, the danger is not comparable to that of the first, because the parts, from the rough handling they have been subjected to, now tolerate in- jury better; but mainly for the reason, that the walls of the bladder and vagina have consolidated about the fistula from the previous inflammation, thus effectually preventing infiltration of urine. No woman in whom this “strange and eventful” treatment is carried out to the end, can be expected to escape this operation; which in its simplest form is an evil of magnitude; for it is not conceivable that the fistula would so adapt itself to the requirement of the case as to close spontaneously just at the time it is considered no longer needed. The above I believe to be a simple and true statement of the circumstances of the subsequent operations. This is the method, involving so much of pain, and suffering and risk, that is proposed, and to some extent, practiced as a therapeutic resource in chronic cystitis. Says Dr. Emmet:—“A certain number of cases of long standing, however, exist where the walls of the bladder have become thickened, and this hypertrophy is kept up by the increasing effort to force out every drop of urine as it passes into the bladder. This condition, I believe, is incurable by any other known means than that gained by the rest afforded after creating an artificial opening.” There is still room for the opinion, which I think is entertained by many in the profession, that all these cases, curable by any means, can be successfully treated by judicious and safe methods. The principle of rest in the treatment of disease and injury is beautiful, most kind and effective in its influence. It is applicable to these cases when brought to bear on them in an easy and natural way, and without the intervention of a method causing unrest, perturbation and risk to life. It is said it is not proposed to resort to this procedure “under any circumstances until other means of relief have failed.” I should not consider that “other means” had been sufficiently tested until they had been tried and re-tried, under the most favorable circumstances of faithful, skillful attendance, and willing, obedient, cooperative patient, taking advantage of time, and rest, and all things; and then persevering until the patientis relieved, or found to be hopelessly incurable: and even in the last sad state I should expect “other means” to afford her some amelioration. I am willing to concede, however, that the fistula once successfully established, the current of the urine diverted from the urethra, and the patient no longer required to perform urination, the sense of relief is sudden and great. But the captivating result is purchased at too great a price; and a patient with this disease treated by the most faithful and favorable application of ordinary and safe means, has, in my belief, a far better chance for relief and continued comfortable existence than one treated by the extraordinary and unsafe method by fistula. Furthermore in this disease no exigency arises justifying an extreme measure, as in the conditions jus- tifying or calling for lithotomy, herniotomy and all the great legitimate operations of surgery. The conclusion of the whole matter is that the prac- tice should be condemned; at the same time I much regret that this is at variance with the estimate placed upon it by some of the Great in our profession. —º-º-º- AN ACCIDENT IN THE LABORATORY..—On Thurs- day, Dec. 21, a most distressing accident occurred in the laboratory of the Josephinium at Vienna. The Professor of Chemistry, Dr. Schneider, was busy with some chemical investigations when a sudden explosion took place in a glass vessel shattering it to pieces and wounding the chemist so severely about the face as to endanger sight in both eyes.' JAN. 27, 1872.] TIH. H. C.I.I.INI c. 43 S T I IL L. B I R T H [. Its Pathology and Therapy. An Abstract of a Review of Schultze’s (Jena) work, “Der Scheintod der Neugebornen” (from the Archiv. für Gynaekologie, vol. II, Sec. 3, 1871). The author defines still birth as an intra-uterine Suffo- cation of the living child and shows that the apoplectic and anaemic forms have a common cause with the purely suffocatory type, viz., interference with the placental respiration. For while brain pressure by irritation of the vagus causes a reduction of the pulse, anaemia by diminishing the activity of the heart's action with con- sequent back action upon the placental interchange produces the same results. Brain pressure and anaemia are the rare causes of placental disturbances; to the same effect tend more frequently, severe pains with short intervals, tetanus uteri, hemorrhages, syncope and death of the mother, premature separation of the placenta pressure on the cord, etc. The injurious effect of prem- ature respiration depends upon diminution of pressure in the umbilical arteries in consequence of the fullness of the vessels of the lungs as well as upon the distension of the right auricle, sequitur of the cava and umbilical vein, associate with the closure of the foramen ovale. The facts that the first acts of respiration in living children are marked by loud rales and that the first ex- cretions contain albumen show that these children have inspired prematurely. When on post-mortem, foreign substances are discovered in the trachea and bronchi, this premature respiration is proven : yet in some cases inspired substances may not be present; this happens or not, as may be understood, according to the disposi- tion of the face. In these cases there is found marked pulmonary hyperamia, with subpleural ecchymoses, a condition which may be referred in most instances to futile attempts at respiration, but which may result, on the other hand, from compression of the cord and stasis in the aorta and ductus arteriosus. The aspired sub- stance is liquor amnii with meconium and vernix caseosa. In exceptional cases, also, during operations or explorations atmospheric air may be inspired by the foetus. In these cases the lungs are usually only partly vesiculated. Sometimes the foetus begins, then, to cry in utero. If the presence of inspired substances be not recognized in the trachea and lungs of the still born at maturity, if the lungs be not found, then, in a condition of hyperaemia, the author concludes that death has oc- cured by protracted Suffocation without any preceding act of respiration. On account of the great flexibility of the costal cartilages immature births- may execute with open mouth acts of respiration which nevertheless fail to carry air to the lungs [The lungs may be found perfectly void of air, even after distinct extra-uterine effºrts at inspiration as Schröder has recently shown. Rev.J. Profound asphyxia and absence of rales in the resuscitated are signs that there has been no premature effort of respiration. The most marked grade of intra- uterine asphyxia may occur without any previous res- piratory effort, if interference with the placental respi- ration slowly increases. To this class belong those cases of still births which have lain for hours long without ... respiring, have been almost buried, indeed, when resus- citation finally occurred. They are only explicable on the assumption of a slow but profound reduction of the excitability of the medulla. Asphyxia, associate even with meconium discharge, may be, as is well known, only transitory in the course of labor and disappear entirely before its termination. This is because the disturbances of circulation induced by premature respiration have ceased with the relief of the disturbance of the placental respiration. Should the cause of the placental disturbance continue, the child usually makes repeated efforts at respiration, be- comes profoundly asphyxiated or dies. Further, it is not of rare occurrence for the foetal heart to be markedly retarded during the last uterine contraction and in this case the child begins to breathe unusually late. [While such a reduction of the heart’s activity, recognized by anscultation, does not, therefore, call for operative inter- ference in rapid termination of delivery, yet it teaches us not to dally too long in the preservation of the perin- eum, rather to hasten delivery, when necessitated, by sufficient section of the perineum (episiotomy) Rev.] In general, the prognosis is more favorable in cases where asphyxia has ensued without previous respiration than when this has previously occurred; most unfavor- able it is when respiration has been attempted when no air could enter the mouth on account of its position. The author coincides with Cazeaux in recognizing two grades of still birth ; the first, with muscular rigid- ity and red or livid skin; the second, graver, with mus- cular relaxation and pale skin. As Sequelae of still births after resuscitation, are to be considered the con- ditions engendered by the inspired substances. These may occasion atelectases and lobular pneumonias and, alas, only too often, subsequent death. Further, blood extravasations are not infrequent, especially in the brain, and from these may be derived the various muscular contractions of advanced childhood. The reduced excitability of the medulla, the accumu- lation of carbonic acid gas, the absense of oxygen in the blood, the disturbances of the circulation and the pres- ence of inspired substances in the organs of respiration— these are the factors with which a rational therapy has to contend. The author now details the various meth- ods of resuscitation usually resorted to, expresses objec- tions to each, and finally, concludes that his own meth- od, best, and almost simultaneously, fulfills the three most essential indications. In the lighter grades of asphyxia, the cord is to remain intact until the cessation of all pulsation. This is done that the closure of the ductus arteriosus may not be prevented by back action of the blood in the aorta. Mechanical irritation to the 44 [JAN. 27, 1872. T EIIH, C T.I. N. T. C. surface, sprinkling cold water, even immersion of the whole body in cold water, perhaps an emptying of 20-30 grm. blood from the cord are here in place. The asphyxia of the second grade (paleskin, relaxed muscles) demands immediate separation of the cord and induction of arti- ficial respiration by the method of the author. This consists in imparting to the child’s body a swinging mo- tion; the body is bent upon itself in the lumbar region, and then swung at first the head upwards and then the pelvis upwards when it is gradually turned upon its abdominal surface to effect a full expiration with expul- sion of the inspired substances. As the body is now returned to its first position, an act of inspiration occurs. This swinging motion is repeated eight or ten times, when a warm bath follows: then the body is again swung, when a cold bath follows, and this motion and these alternate baths are continued until the child cries or the heart ceases to beat. Should dyspnoea occur, the Swinging and cold baths are repeated. Should this swinging not lead to entrance of air in immature births upon the first trial, catheterisation of the trachea should be performed and air should be blown into the lungs before the motion is repeated. —sº-o-º- scIENTIFIC NoTEs. INFLUENCE OF LIGHT ON SUGAR.—M. Raoult states, in a paper read before the French Academy of Science, that cane sugar becomes transformed into grape sugar under the prolonged influence of light. Having dissolv- ed 10 grammes of white sugar in 50 grammes of pure water and boiled the solution for a few minutes, he placed equal portions in two white glass tubes, which were then hermetically closed. One was deposited in a dark place, while the other was exposed to light. Five months afterwards the tubes were opened, and the contents of that which had been exposed to light gave the reaction of glucose. DIABETES AND THE FOURTH VENTRICLE OF THE BRAIN.—In order to explain the apparently contradic- tory results, Cyon set about investigating the way in which the fibres of the annulus of Vieussens affect the liver, and more especially the circulation in it. On irritating these fibres, he found that a number of fine white lines appeared round the lobules of the liver, in the position occupied by the small branches of the portal vein and hepatic artery; and these were so nu- merous as to produce the appearance of whitish spots on the organ, which continued while the irritation lasted, and disappeared after it ceased. At the same time that these spots appeared, he noticed that any cut or tear in the liver bled less freely than before. This indicated that contraction of the portal vein or hepatic artery, or of both, had been occasioned by irritation of the annulus; but, in order to make assurance doubly sure, as well as to find out whether it was the artery or the vein that contracted, he put a T-cannula into the hep. atic artery, and connected it with a manometer. On then irritating the annulus of Vieussens, the pressure rose in the manometer as much as thirty to seventy millimetres of mercury; while in the carotid it only rose five to ten millimetres. To remove the last objection which might be raised, and show conclusively that the rise of pressure was due to contraction of the branches of the hepatic artery in the liver, and not to any other cause, he compressed the artery beyond the point where the canula had been inserted, so that no change in the calibre of its branches could have any influence on the blood-pressure in its trunk. On again irritating the annulus, he found that no alteration in the pressure was produced. Division of both annuli produced, as was to be expected, dilatation of the branches of the hepatic artery, and fall of the blood-pressure in it. When the portal vein was experimented on in the same manner, the pressure only rose ten or twelve millimetres during irritation; and he thinks this is probably due indirectly to the change in pressure in the artery. . These experiments completély prove that the vaso- motor nerves of the hepatic artery are contained in the annulus of Vieussens; that their division causes the vessel to dilate, and at the same time produces diabetes. The theory of Bernard, that the diabetes depends on the dilatation, and on the consequent rapid circulation of blood in the liver, is thus rendered in the highest degree probable.—Brit. Med. Journ., Dec. 23, '71. —sº-º-º- NIIEDICAL NEWS. MEDICAL SERVICE IN THE NAVY.—The Secretary of the Navy has recently announced to the navy, in a general order, No. 164, that no assistant-surgeon will be examined for promotion until after he has served in his official capacity “at least two years on board of a pub- lic vessel of the United States at Sea.” This is an accor- dance with the letter and spirit of the law, which re- quires that the professional qualifications of candidates shall be ascertained by suitable examination before they are appointed assistant-surgeons. The requirement of two years' service at sea prior to promotion, specified in the act, is to test the personal aptitude for “life on the ocean wave” without which a medical officer is worthless in the naval service. Gentlemen who have been Com- missioned three years may be examined for promotion at the discretion of the Secretary of the Navy, provided they have been qualified by two years' experience at sea. At the expiration of five years' service they are legally entitled to be examined for promotion, if qualified by at least two years' service at Sea. - THE PEST IN PERSIA.—Dr. Castaldi who was sent out from Teheran to investigate the epidemic prevail- ing in Kurdistan reports his observations to the sanitary council Constantinople to the effect that the epidemic is nothing less than the Asiatic pest. The disease begins with vigor, cerebral disturbance (sopor and delirium JAN. 27, 1872.] and vomiting. At times immediately, at times after a short period, boils begin to appear on the soft parts, in the axillae, and on the neck producing violent pains. Later the body is covered with bluish-black spots of the size of a pea and larger. It is in high degree contagious, ex- tending itself as in Bana from house to house. It first appeared last winter in the village Arbanus, which was totally depopulated. In Bana, 5,000 inhabitants, 150 cases have occurred, of these only 54 terminated fatally. In some of the villages of Asiatic Turkey bordering on Persia the pest has also appeared. HoNORS RECIPROCATED.—From the Constitutionnel we learn that it is proposed by the French government to decorate with the ribbon of the Legion of Honor all the German Physicians and internes who gave aid to the wounded of the French during the late war. The Emperor of Germany has thanked M. Thiers for this, and will in return bestow the iron cross with the white ribbon, upon the French Physicians and internes who distinguished themselves by extending succor to the German wounded. The Constitutionnel is glad that the internes are included in the proposition, and pronounces a eulogium upon this class for their courage, devotion, and self-denial. The Union Médicale of October 3, while agreeing with the Constitutionnel as to the merits of the internes, thinks that their patriotism will in- terfere with their wearing the iron cross or deriving great pleasure from its possession.—Phil. Times, Jan. 15, 1872. SMALL-Pox IN GERMANY.—The epidemic of this disease in Vienna is rapidly increasing. The number of deaths has not yet reached the proportions announced in Berlin, Breslau, etc., but it is already of such extent as to necessitate the construction of a new ward for small-pox patients in Prof. Hebra’s department. —-º-º-º- * CORRESPONDEN CE. VIENNA, AUSTRIA, December 18, 1871. - EDs. CLINIC: - I thought last night I should be able to write a short article to-day on vaccination, giving reasons why a good many physicians were opposed to it, etc. But on looking over some of the literature on this subject and especially syphilis vaccination, I find that it would require several days study to enable me to state what really has been proven and what not; time, which I cannot just now devote to such studies. Hence I will tell you what my ideas are on the subject and what I know to be fact. It is asked why are German physicians opposed to Vaccination ? Before answering the question itself. I find it necessary to protest against the assumption that the German physcians en masse are opposed to this measure, or even that a majority of them stand in any Way, in an attitude of opposition. I am forced to this T THE EI, C T , IISTIC . tion must be admitted. this city. 45 belief from what I read in German medical journals, as well as from what I hear and see in the several hospitals here. That a few are strenuously opposed to vaccina- The question “why” can be answered in a few words. It is preeminently the fear of syphilitic contamination. A quite secondary reason may also be the circumstance that even successful vaccina- tion does not entirely protect every individual against Small-pox. Is there sufficient cause to be afraid of syphilitic contamination through vaccination ? Un- doubtedly there is, for it is an admitted fact, that the blood of syphilitic persons if introduced under the cuticle of the non-syphilitic, will in a certain number of these latter, about 25 per cent., develop the disease ; hence, if vaccinating from arm to arm, we employ bloody lymph we are likely to infect healthy persons; providing, however, the person from whom such lymph is taken was at the moment suffering from some man- ifest form of syphilis. As a matter of course, the con- tamination is certain to occur, if vaccination is made from a syphilitic pustule or syphilitic Sore of any kind or crusts from such pustules or sores. It is not proba- ble, however, that any physician will in this manner spread the contagion, inasmuch as such practice would at once prove the offending party guilty of either gross ignorance, or criminal neglect. I will not maintain that in past years children and grown persons may not have been thus infected, on the contrary, it seems pretty well established that it has occurred; is however less likely to happen in future, because much more care will be exercised in the selection of vaccine-lymph, or crusts. This much the opponents to vaccination have established. But they have done more, they have spread distrust and horror by publishing as syphilitic, many cases which, at most, were what the dualists call chancroids, a peculiar ulcerative process, not producing any constitutional symptoms. Now, is all this sufficient cause to be opposed to and to discourage human vaccination ? Not at all. In the first place the danger of contamination has been largely overestimated, magnified. This is conclusively verified in every country where vaccination is practiced. As an instance I will simply cite the Foundling Hospital of Here about fourteen hundred children are vaccinated annually. The institution also furnishes vaccine-lymph to all vaccination districts in the Aus- trian empire, besides sending some abroad: one hun- dred and fifty tubes having been lately sent to Cincin- nati. The present Director of the Hospital, Dr. Fried- inger, has held this position for seventeen years and for two years besides was assistant in the institution. During all this long period with this great number of vaccinations annually, Dr. Friedinger has not, so he has informed me, seen a single case where syphilis had been communicated through vaccination. In one instance he took lymph from a child which a few days later showed unmistakable symptoms of syphilis. The vac- cinated child was kept under observation for a year, or 46 [JAN. 27, 1872, TIEEE THE C T , T: INTT C. more, and no syphilis ever manifested itself. Here, then, we have an instance where one man has performed upwards of 25,000 vaccinations, without having seen or learned that in any instance he had communicated syphilis, and this too, in a city like Vienna. Dr. F., however, exercised great care in the selection of his lymph sources, only strong, healthy children, free from every syphilitic manifestation are used as Stammimpflinge [sources]: the vesicles must bear the characteristic marks, and be not over seven days old, counting from the day of vaccination. All dwarfish, or abortive vesi. cles are to be avoided, likewise, and, particularly so those in which pus-cells have already been formed. Nor does it seem to be a matter of indifference as to how the operation is performed. Dr. Hobner, of Fratz, recently reported a case in point. He vaccinated from the same source a healthy child on both arms; on One arm by the method of very superficial incisions, on the other by somewhat deep punctures. On the first arm a typical vaccinia development was the result; but on the second, where puncture had been resorted to, in- stead of having a dry crust at the end of the third week an ulcerative process set in, and cicatrization did not take place until the end of the fifth week. The facts noted, it seems to me, go to prove that we need have no fear of syphilitic contamination if we will but observe the rules generally laid down for the guidance of vaccinators, and which are none other than those incidentally referred to as followed by Dr. Fried- inger, viz: To use as “Stammimpflinge” [sources] only strong, and as far as possible, healthy children ; the lymph to be taken from none but entirely normally developed vesicles, and not later than the seventh day, counting of course from the day of vaccination. Any vesicle, the contents of which are turbid, milky, or bloody should be scrupulously avoided, for there can be but little doubt that, in all cases where syphilis has been carried from one to another by vaccination, the source was just such a vesicle or pustule. The age of the “Stammimgflinge,” should also be taken into ac- count, it should not be less than six months, one year is still better. One reason for this is that congenital syph- ilis almost invariably manifests itself during the first six months of life; by far the greatest number occur during the first three months of life. In performing the operation itself care should be exercised to wound the cutis vera as little as possible; simply removing the epidermis by scratching, etc., seems to have given the very best results. In regard to minor objection to vaccination ; that it is not a perfect and permanent protection against Small- pox, it may be stated without fear of contradiction that a successful vaccination affords so nearly perfect protec- tion against variola, that the failures are but an in- finites mal per cent. Of those who subsequently suffer from small-pox, again, but a small per cent. have to go through severe grades of the disease; the large majority of vaccinated Small-pox patients being light cases, coa- sequently the rate of mortality among these is much lower thaa among those not vaccinated. To conclude then, I see no good and valid reasons why anybody, least of all a physician, should be opposed to judicious vaccination. - - Yours Truly, J. TRUSH. EDS. CLINIC : I was not a little startled on reading a paragraph in the number of your paper of the 13th headed “SUICIDE BY MORPHIA HYPODERMICALLY,” and a notice follow- ing of the death of the late lamented Col. David Stan- ton, M. D., of New Brighton, Pa. Now there is a dash of malignity in the caption to the short article referred to, that is perfectly inexplicable to me when I look at the high character of the names of those who conduct the paper, as well as the unexceptionable tone of the entire paper itself in other respects; and "I cannot avoid respectfully calling attention to this matter with the hope it may be accounted for by some inadvertence. If there was anything in the circumstance attending the sad fate of my friend Dr. Stanton, that warrant such an unqualified use in connection with it, of what in modern times is almost universally regarded as an extremely opprobious term, those whose opportunities were excellent for knowing the facts are still in ignor- ance of it. I trust the numerous friends of the de- ceased gentlemen, both in and out of the profession to which he belonged and adorned, may be relieved of the feeling which is engendered by such a public announce- ment as above, by the appearance of some satisfactory explanation. . - .* I am very Respectfully, Yours, cte. - * L. M. Whiting, M. D. CANTON, O., Jan. 20, '72. The notice of Dr. Stanton's death referred to was clipped from the Atlanta Med, and Surg. Journal, Nov., 1871. As Dr. Stanton was an entire stranger to the Editors of this paper, the “dash of malignity” is nonsense. Dr. Stanton killed himself accidentally. That is the fact and that is the tenor of the letter in the Atlanta Journal and the note in THE CLINIC. - It is a matter of regret, however, that any misinter- pretation of the statement has arisen, particularly as it turns out that the deceased has near relatives both in the medical and legal profession in this city.—EDs. CLINIC, º —-º-e-º- C LINICAL VIEM IORANIDA. THE REMOVAL OF MORBID GROWTHS FROM THE LARYNX BY SECTION OF THE CARTILAGES.—Mr. Arthur Durham read a paper before the Royal Medical and Chirurgical Society (Lancet, November 25), in JAN. 27, 1872.] 47 which he related in detail five cases, in each of which the operation had been performed in Guy's Hospital,— in three cases by himself, in one by Mr. Bryant, and in one by Mr. Colley. The result in four of these cases had been eminently satisfactory, free respiration and good voice having been regained. The remaining case was still under treatment. Appended to the communi- cation were more or less complete reports of all the cases the author had been able to find on record. These cases were thirty-two in number, and, with the five de- tailed in his communication, gave a total of thirty-seven. In nineteen of these the operation might be regarded as having been completely successful, natural respiration and voice (though in some instances not normal in tone) having been restored. In seven partial success was ob- tained, respiration having been restored, but the voice lost or very seriously impaired. In four cases some temporary relief was obtained. In three the result might be considered negative, neither good nor harm having been done. The reports of at least two cases were incomplete. In two cases—and two cases only— death resulted. In each of these, however, the im- mediate cause was blood-poisoning. Metastatic abscesses were found in the lungs in one case; in the other erysipelas and gangrene occurred, and broncho-pneu- monia and exhaustive fever ensued and led to a fatal issue.—Phil. Times, Jan. 15,’72. BULLET ExPLORERS.—The Improvements which have taken place in the modern applications of electric- ity have paved the way for more simple and yet more sensitive bullet explorers. One of these is the invention of Mr. De Wilde, a civil engineer, and is very compact- ly arranged in a box of small dimensions. The electric action is excited in a suitable cell; the electricity there developed is increased in intensity by the invention of a multiplying coil; an exploring probe is connected by insulated wires with the apparatus; and the indication, when the circuit is completed by contact of the two points of the probe with a leaden bullet or piece of iron, is given by the striking of a hammer against an alarm ‘bell. The bell sounds at each interruption and renewal of contact of the points with metal. The ex- ploring probe consists of a long slender tube of smooth vulcanite, containing two insulated needles, the points of which can be withdrawn within the tube, or be made to protrude, at the pleasure of the operator. Altogether it is an effective appliance as an exploring instrument, owing to the strongth of the electric current developed, and the marked manner in which the indications are given by the sound of the bell when a bullet or other metallic substance is met with. There is also attached to the instrument a bullet extractor, the two arms of which are insulated, and so arranged that, when they are connected, in the same way as the explorer, with the battery, they indicate the grasping of the foreign body similarly by the sound of the bell. Unless the metal be firmly grasped by both blades, without any other substance intervening, the indication will not of course be given. Another instrument of a similar nature has been made by Messrs. Krohne and Sesemann of London. The indications of contact with a lodged bullet or other metal are in this instrument afforded by the movements of a galvanometer, and of a fine needle working upon a dial-plate, in the same manner as is seen in the ordinary single needle telegraph. I have experimented with both instruments, and have found them equally effective in their indications. Attached to the latter instrument is not only a bullet-extractor as well as the explorer, but also a pair of acupuncture needles' for use in cases where metallic bodies are supposed to be lodged in soft tissues, away from any means of approach by a wound or sinus. A rough but sufficiently effective electric instrument for facilitating the discovery of metallic substances lodged in gun-shot wounds has been made in the follow- ing way. The magnet of an ordinary pocket-compass, which has had some turns of wire covered with thread wound round it as an induction coil, is employed for the electric indicator while a piece of copper sheeting, bent round a small plate of zinc, but separated from it by flannel padding Saturated with the usual diluted acid, forms the voltaic pile. The exploring instrument is formed by two insulated wires, bound together, but with the points left free. These parts being connected, when the circuit is completed by contact with metal, the indication is given by movement of the magnet of the compass-Longmore—Brit. Med. Journ., Dec. 30, 71. – sº-º-º- º - - The Iodides of Ammonium and sodium in Syphilis. IBY BERKELEY HILL, M. D. Surgeon to University College Hospital, It not unfrequently happens in cases where iodine is required, and the patient has taken iodide of potassium with good effect for a certain time, that this medicine either ceases to produce any result, or is no longer toler- ated. Faute de mieux, mercury is sometimes resorted to ; but, as the cases are not suitable for mercury, they generally become worse while taking it. In this diffi. culty, the iodides of sodium and ammonium are very useful, for they affect the body somewhat differently from the potassic salt. They can be borne by, and pro- duce the effect of iodine in many persons who have be- come nauseated by the latter. They moreover contain less alkali per weight of the Salt, and their alkali is less deteriorating to the blood than potash. One or two cases will illustrate my meaning. A gentleman was brought to me by his medical adviser, with extensive and obstimate syphilitic ulcers of the tongue and palate. He had had several other forms of syphilis during the nine or ten years he had been infected, and was in a 48 [JAN. 27, 1872. TIEEI IEH C T , I INTI C. weak and low-spirited condition. Early in the disease, he had taken mercury and other remedies in the usual way. Latterly, for the ulcers in his mouth, iodide of potassium had been given in doses gradually increasing to a scruple, and even half a drachm; but, when I was consulted, these had ceased to check the disease, and had produced iodism. In consequence of this, mercury and several other drugs had been tried again without benefit. Though his tongue was foul, his appetite, but for the pain of eating, was good. This is important; if the di-. gestion be deranged, it must be set right again before iodine can have fair play. Under these circumstances, the patient was ordered to begin with eight-grain doses of iodide of ammonium in bitter infusion three times daily. He bore this well, and in the course of a few weeks his tongue and palate were nearly healed. For complete cicatrisation it was necessary to alter the form to iodide of sodium; and, during two years, he has been taking this salt at short intervals to prevent the relapse of his disease. Here is another case of syphilis appear- ing unconquerable by either mercury or iodine, which had been given by several medical men whom the patient had consulted. The case was interesting from the probability of its being one of contagion through an infected monthly nurse “sucking the breasts.” The child was infected at the mouth subsequently to its mother, and the history in the mother points to con- tagion having entered by the nipple. patient until two years after infection; she had then severe ulceration of the tongue and of the soft and hard palate, and limited necrosis of the bone in the palate. From the prescriptions which she showed me, she had been taking scruple doses of iodide of potassium, for some time with good effect; but, latterly, even double doses of her medicine had only produced severe iodism without controlling the disease. It was with some reluctance that she consented to try iodine again; but, after a few eight-grain doses of iodide of sodium, coupled with frequent washing of the mouth with hyposulphite of soda and glycerine lotion, her sufferings were so far removed that she announced, a week afterwards, that she could eat crusts with ease; and, in a month, except that a morsel of necrosed bone still adhered, the mouth was quite well. The course of this case since has been obstinate; gummata appearing elsewhere after that in the mouth had healed; but she still takes iodine, some- times in one salt, sometimes in another, and occasionally mixed with Bell’s liquid extract of Sarsaparilla. It would be easy to multiply instances where, iodide of potassium having lost its effect, the progress towards recovery can still be maintained by another form of iodine; but that is needless.-Brit. Med. Journ., Dec. 23, 1871. - JIM FISK's brain is said to have weighed 59 ounces. Cuvier's, notably the heaviest, weighed only 64 ounces. Fisk’s is heavier than Simpson's, the fifth heaviest, in- deed, recorded. It would be interesting to have the particulars as to the number and depth of the convolu- tions, etc. Possibly the science of bumpology might receive some additions. I did not see the Medical College of Ohio. . S P R N G C 0 U R S E , The regular eight weeks course of practical instruc- tion for the Spring of 1872 commences March 15. Un- usual advantages are offered this year in the fact that the course will be conducted by the entire Faculty of the College. - - The course will embrace the following topics: Clinical Medicine—Bartholow. “ Surgery—Dawson. Anatomy Brain and Nervous System—Gobrecht. Operative Surgery—Conner. & 4 Obstetrics—Reamy. {{ Ophthalmology—Seely. Female Pelvic Surgery—Palmer. Urinalysis—Nickles. - Physical Diagnosis—Cleveland. & Fractures and Dislocations—Kearns. Genito-Urin. Dis.—Anderson. Microscropy—Whittaker. Prof. Graham will deliver occasional lectures on Clin- ical Medicine and Diseases of the Chest during the pro gress of the Course. - The design of the Course is to present instruction in a thoroughly practical manner. Physical Diagnosis is to be demonstrated in the hospital wards; Operative Surgery, Operative Obstetrics, Operative Ophthalmology, and Operative Gynaecology on the cadaver. - - The Dissecting Room will be under the supervision of Dr. where abundant material will be provided. Special attention will be paid to the chemical and mi- croscopical analysis of morbid urine. In order to render this course the most practical pos- sible, an opportunity will be afforded each individual of the class to make the various examinations and opera- tions on the living and dead subjects. Regular daily Medical and Surgical Clinics will be held at the Good Samaritan Hospital: Two Daily Clinics will be regularly held in the Cincinnati Hospital, throughout the . entire course; and a Daily Clinic will be held at the Dispensary of the Medical College of Ohio. One hour each evening will be devoted to Recitations on Anatomy, Physiology, Practice, Surgery, Obstetrics, and Materia Medica. - The eminently practical nature of this course, and its shortness of duration, together with the great clinical advantages presented in Cincinnati, can but commend themselves favorably to the practitioner as well as the student. FEES FOR THE ENTIRE COURSE, $10 As this Course does not count towards graduation, being considered supplemental to the regular winter course, graduates of the College are not required to matriculate. The matriculation of non-graduates is deducted from the fees of the ensuing winter session. ** F. E. Suikº. E. S. WAYNE F. E. suire & Co., wholesale DRUGGists, TM A-IN U E A CT Uſ ER, ITN G. £Hemists AND PHARM aceutists, CINCINNATI, OHIO. Have constantly on hand w full assortment of seveereo waves Aso moeoxexses, cxxxery)(XCA), AXºAX3A%Us, TESTs, MEDICAL GLAss war.B. &c., &c., And solicits the patronage of the trade and profession. We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, Made in accordance with the U. S. P. and other recognized authori- ties. FINFE AND RAF HE CHEMICALS, Of the popular class of preparations known as II, T, IL& IIER, S, We manufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. Bitter Wine of Iron, An excellent Chalybeate and tonic, Wine of Iron, &c AGENTS FOR BULLOCK & CRENSHAW's Sugar-coated Pills and Granules. ) Price Lists of preparations and of Sugar-coated Pills sent by Mail upon application. The long standing and well and widely known repu- tation of our house we offer as a guarantee for the reliability of our | Preparation, and the quality of the goods sold by us generally. TER, º; §§ " ; ºf sº JAMES FOs Wººl JR., & Co. |Instrument Makers and Practical Opticians, Beg leave to return thanks for the patronage extended to them through a loug Heries of years (having been established since 1836), and in the reorganization of their firin will endeavor to merit a continuation ºf the same. We wish it understood by the Professiºn and the Public generally that our invariable rule is, ſo make or import none but the best in- struments. Those in want of any of the acknowledged good aids of vision to imperfect eyes, will always find the best and largest stock of Lemases, Spectacles, and the best models procurable, with pains- taking skill to adjust them to all contiitions of sight. at our house. Special attention paid to orders for Fine Microscopic Objects and Microscopic Apparatus, Magnifiers and Readers in great variet v. Medical Batteries, Barometers, Thermo- Rhaeters, Hygrometers, Urimometers and Rain Gauges, of the most approved coustruction always on hand. All orders promptly and accurately filled. JAS, FOSTER, JR. dealing F. S. SHACKLEFORD, ! *** ** IAs. FostER, JR. & Co. S. W. Cor. Fifth & Race Sts., Cincinnati, 0. T)IER, S-INT-TV/I_A_IER/STEI’S TRUSSES. No. 758 BRoapway, NEw York HAVE been in the habit of applying and recommending the Truss manufactured by Dr. S. N. Marsli. for the last eight years, tº the ex- clusion of all others, and have found it to give general satisfaction. eflect- ing a radical cure, in the majority of cases, in a very fºw months. As a Truss for the radical cure of Hermia, l think it lar prº-ferable to any I have ever examined. LEWIS A. SAY li E, M. D. - Surgeon, Bellevue Hospital. From Prof. Willard Parker to S. D. Townsend. M. D., Surgeon to the Massachusetts General IIospital. B EG leave to state for the benefit of all concerned, that I have known lºr. S. N. Marsh the last fifteen years. St I am in the constant habit of sending my patients to him for treatment. I have been delighted with lais Truss, and the success he has met with in producing a Hindical Cure of líernia. He has instruments superior to any I have ever seen, and his treatment is unattended with au v of the risks to the pil lient that exist in inany of the plans suggested and attempted to be carried into execution. I have confidence in Dr. Maish as a gentleman of honor and integrity, and as such recommend him to the metal bºrn of the medi- cal profession generully. Wil, LA 1RL) l’Alt 1 E.R., M. I.). Professor of Surgery, New York City Dr. S. N. Marsh's Patent Radical Cure Truss, and all other kinds of Trusses, Shoulder Braces, Supporters. Elastic Stockings, SuspenRory Bandages, Apparatus or Spinal Curvature, Club Feet, bow Legs, and all other Physical Deformities, made and accurately fitted at the Ratlical Cure Truss Offices of S. N. M.A RSil & CO., No. 2 Wesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. OPPOSITE THE IIIGEI STEEPLF, O Carriage Manufacturer, **** NOS, 9 and 11 East Sixth Street, bet. Main & Sycamore. I MAKE NOTHING BUT AEA ſº,S 7" CZ.Z.S.S. W. 62/PA’. Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of LIGHT FAMILY CARRIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive variety of light elegant designs of different cost and finish. In vehicles especially adapted to • - PHYSECHANS” USE. The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. The superiority of my light gentlemen’s buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price lists furnished on application. References to Dr. W. W. Dawson and all the leading Piysicians in the city and heighborhood. ||||||||}|| ||||||}|| ||M|| 167 EAST 34TII-ST, NEIV Yo RK, By Special Appointment Electrical Instrument Makers tº the New York State Hospital for Nervous Diseases, ELECTRO-MAGNETIC MACHINES, Portable Galwamic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, 1870, and May 30th, 1871. : These Instruments are the most Elegant, Powerful, Effica-| cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery I'luid. - |M|| |||||—||M|| ||||||||}| PERMANIENT BATTERIEs, For Hospitals and General Practitioners, IET IIECTIER, OTDIEBS. For Bye, Ear, Larynx, Nose, Uterus, Vagina, Bladder, Rec- tum, Feet, Phrenic and Sympathetic Nerves, Eleo- trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. * Exrn Arts ritor trºm o Prwroxs or The wrosal Elliſ I.N EN I" M.E.M. ºf EItS (/ F T'Lº ſº PIE OFESS f ON. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “Not HING cAN EXCEED THE EFFICIENCY AND CONVENIENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” - "We are authorized by Prof. IIammond to announce en- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- proved and re-modified Instruments made by our Company. M EREDITH CLY \l ER, M. D., Prof. of Diseases of the Neº- vous System and of the Mind, &c., &c.—“ I consider their Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prof. of Surgery, St. Louis:–“ In neat- ness, compactness and efficacy, they can not be excelled.” ALFRED C. G. ARRATT, M. D., Boston :-"In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” Similar Testimonials have been received from JOHN J. CRANE, M. D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A. MURRAY, M. D.; CHAS. E. BLUMENTHAL, M. D.; E. C. SEGUIN, M. E.: ALLEN MAYN A R D, M. D., Cleveland, O.; Dr. C. WANN E, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES | KELLY, Florence, O.; Dr. JOIIN BECKER, Brighton, Iowa; Dr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes. barre, Pa.; JOHN J. CALDWELL, M. D., Brooklyn, and mauy other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an Electrical Instrument for medical purposes. call of send FOB CIRCULAR AND PEIGE LIST. SAML. P. THOMAS T.A.. I DEALER IN English, French and Scotch GOODs, 34 West Fourth Street, crwczºwycz Tr. Fosºrr:R's, IE_A_TIENT & § §§ Are furnished to Officers and Soldiers on Government il CCOUI n t- - I claim to have combined such improvements in ARTI. FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb – why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb—why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs — testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMES A. FOSTER. 911 Chestnut Street, Philadelphia, Pa. No. 60 West - Fourth street. Cincinnati, Ohio, or 172 Jef. ferson Avenuto, Detroit, Mich : Eºjī. #ſºft# Sé= --~. sº Éjºš. §º ºššíř: §§ § º - |*|| “.." ' ' ' ' ' ' ' '. ...'... ºn "Wº tº - : '. § # # # | | º | i. . * | ſ |ſº Hºzºs rº E º º | # i #| || | º ##|t º ji=jīšāºš =#|###| ||ºj | º |#####|-ºxº §:=#º: |†† #ºmiſſil ºf %; §§ §§º jºjº # Hºliº §. | º Bºšº º ". s: ::: #: w #. | sº # § # - * º º §§ §Mºº *.i § pº § Sº Yº w §* M º'E's - § i. | ñº; º:S jºiºſºs #. º:- - º,' s º % £ºft º º'º ºf 3.4% E-Z w º % % 2^ º'º' . * ºf 3% % tº . º ºzº * 3ºz º. : * * §§- ſº Zºº & - ºts'." ºšºft := T Rºssºft 2% --> ==S--iºsº % 2 - -º-º-ºss º- sº %22% * ...--º-º-º-ºsmºme- cº--> * :--> Etºss *~ f Zºº. Good sa MARITAN HOSPITAL. The GOOD SAMARITAN HIOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner of sixth and Lock streets. It is handsomely furnished throughout, and is provided with all the necessary ap- pointments of a First-class Hospital, Porticoes, with commanding views, surround the whole house, and wide halls and abundant windows secure that full and free ventilation which is so essential to health and comfort. Service is furnished by the - - SISTERS OF CHARITY, Under the Superintendence of the well-known SISTER ANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. The regular Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each Professor presiding over his own especial department. Patients may, however, select from the regular profession of the city any physician of their choice. The GOOD SAMARITAN HOSPITAL presents extra inducements to Invalids throughout the State as a safe and quiet asylum in any case of protracted illness, or in cases, more particularly, requiring Surgical Operation, where some stay is necessary in after treatment. - Rooms vary in price, according to the character of appointments necessary and service required, ranging, ja general terms, between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand of service. Bºy" Address, SISTER ANTHONY, - *-*. y Hospital of the Good samaritan, corner of Siacth and Lock Sts., Cincinnati, Ohio- M A F P& T VVA. I. N'S - N E VV TB O O IX IS NOVV READY FOR CA N VASSERS. It contains over 600 pages of reading matter, with 250 engravings, designed crpressly for this work, by the best artists in the $ountry. A gents now at work upon it are meeting with unparalleled success. A gents at Circleville, O., reports 25 orders in 2 days; one at Louisville, Ky., reports 175 orders in 8 days; one at Middletown, Conn., reſorts 200 orders in 12 days; one at Cincinnati, O., re- ports 250 in 12 days. Early applicants secure choice of territory. For circulars, terms, &c., address NETTLET ON & CO., 161 Elm Street, Cincinnati, O. *- BASCOM & CARPENTER, Printers Sy. Stationers, -AND- Blank Book Manufacturers, 136 VINE sºrrle ET, s\ssºs E. D. ALBRO & BRO. IMPoirTERS AND MANUFACTURERS OF FOREIGN and DOMESTIC WOODS In Veneers, Boards and Plank, frtaint-Mikº','!-Buliiſi'ani Star-Bilº'Wit. The only house in the Western country that saws Spanish and Mexi- can Cedar for Cigar-Box Makers We import our own wood direct, and can sell at prices to compete with any and everybody. Also saw and keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. Office and Warerooms, 136 and 138 West Second Street, Veneer Mill, 507, 509, 511, 513 & 515 W. Sixth St., CINCINNATI. CAN'ſ A F&G-O MANUFACTURING COMPANY., MANUFACTURERS AND IMPORTERS OF A N D Window Shades, 67 WºSz" Fotºzºzy Szººgz", CINCINNXT, O, H. H. BRENEMAN, Proprietor, UNDER WEAR GENTLEMEN. Handling much larger quantities of fine and valuable Underwear than any other firm in the West, we are enabled to purchase at closer fig- ures. We are therefore prepared to offer extra inducements to consumers. HO's IEERY, FULL LINES OF THE BEST ALWAYS ON HAND. SHIRTS MADE TO ORDER. wilson BROS, Pilke's opera House, Cincinnati; 931 Wabash Awe- nue, and ss West Washington street, Chicago- 2. 2. s ź. i | § w "gººº 2: i. s A. 2. - - *— '' - Eºº ºr - - 21st- Bºº. inimi; ; Riº mimim, fift. º Fºil i. - Sl lºss. Sº Aº º % º; WWAS E : ". - I F A C U L T Y. J A M E S G FR A H A M, M. D., DE AN, Professor of the Theory and Practice of IMedicine and Clinical Medicine. ROBERTS BARTHOLOW, M.D., - W. W. DAWSON, M.D., Professor of Materia Medica and Therapeutics. Professor of Principles and Practice of Surgery and Clinical Surgery W. H. GOBRECHT, M.D., º C. D. PALMER, M.D., Professor of Anatomy. - Professor of Medical and Surgical Diseases of Women. P. S. CONNER, M.D., T. A. REAMY, M.D., Professor of Surgical Anatomy. Professor of Obstetrics and Diseases of Children. W. W. SEELY, M.D., JOHN L. CLEVELAND, M.D., Professor of Diseases of the Eye and Ear. - Demonstrator of Anatomy. SAMUEL NICKLES, M.D., CHARLES KEARNS, M. D., Professor of Physics and Medical Chemistry. Assistant to the Chair of Surgery. J A M HE S T . W H ITT A EX E. F., Professor of Physiology and Secretary of the Faculty. T. Louis BRow N, Prosector of Anatomy. Janitor, College Building, Sixth St., bet. Vine and Race. Printed and Published by Nor R1s & Mr RRY, Medical College of Ohio Building, Cincinnati, THE CLINIC, PUID. LISIIIED IF VIEIRY SATUIR T E R M. S.–$2.00 a Year, Invariably in Advance. All Communications relating to Tublications must be addressed to the Editor: {DAY. * All Communications relating to Dusiness, Subscriptions, Advertisements, etc., to the Treasurer. Vol. 2. gº tº º Editor. sº JAS. T. VVH ITTA KER, M. D. No. 101 west Ninth street, Cincinnati. Asso~t.A.T.E. F.Torrors. W. W. T.Aws, N., M. D. Tii Ap. A. REAMy, MI. D. P. S. CoNNER, M. D. C. D. PALM ER, MI. D. W. W. SEELY, M 1). SAMU Fr. Nicku,Es, M. D. CHAs. KEARNs, Mſ D. JNo L CLEVELAND, M. D. Rob ERts BARtholow, M. D. C IN C IN N AT I, F E B R U A R Y 3, 1872. W. W. SEELY, M. D. • * * ~ *, * TREAstiter. No. 118 West Seventh street, Cincinnati. C L U B R A T E S, 4 Copies to one address................ * * * * * * * * * * * * * * * * *s º ſº º te is is tº sº e º is sº is tº a tº $ & e º ºs $ 7.00 6 { { “ .................. 10:00 12 & & “. ...................................................... 18.00 C O N T E N T S. - oitre+När, ARTrcies’ Some Medico-Legal Questions in the Watson-Shryock Murder Case, by Roberts Bartholow, M.D...................................................... 49 Page, Ophthalmist Neonatorum, by W. W. Seely, M. P.” “…& Atropia as an Antidote to Opium, by W. L. Buechner, M. D............54 THRANSI L A' N; © N On the Surgery of War, being an Abstract of a Review of Pirogoff's Report on the Franco-Germanic Service (from the Allgem. Militärärztl. Zeitung, Dec. 24, 1871.)............. tº a n e º 'º e º a tº º e º * * tº e < * * * * * * * * * * * 54 • SCIENTIFFIC NOTES Multiple Metastatic Abscesses—Transfusion of Blood M.I.E.[PHCAI, NEWS American Malicine—Honors to the Physicians of the Prince—The Rites of Found \tion Sacrifice—Circumcision of Corpses—A Valuable Carrier Pigeon—Small Pox in Germany—ceremonial & Purification c1. IN 19 A1. MEM ort ANDA A New Remedy for Small-Pox—Chloral in Gout—Charcoal in Gas- tric and Enteric Disorders—Chloride of Ammonium in Hepatic ſ (: Abscess—Electricity in Womiting of Pregnancy HOME NEWS * * * *mºnº amºus sº *-i- ºr sºm, ºmsºmºmº. ** = ** *** * * * *= * = • * THE CLINIC from hence forth will be furnished only to regular paid up subscribers. Gentlemen who have recieved the paper during the past month will, if they desire its continuance, forward their subscriptions to the Treasurer without delay. The low price at which the paper is published renders prepayment imperative. Regular subscribers who are minus any back numbers of this volume have but to signify the same at the office of the Treasurer. * co-Ars de co- Fashionable Hatters, #,A}}{ES” # UHS, 92 WEST FOTTER TH ST. Opposite Post Office, º CIN CININ ATI. & Special Inducements to Medical Men. J. TAFT, Editor Dental Register J. & W. TAFT, TIENTISTS 117 WEST FOURTH STREET, CIN CIN NATI, §§§ O. A Monthly Journal, Wº º CONTAINING 48 PAGES, Devoted to the Interests of the Dental Profession, **------- ===- & -:E– -F# == as- - ===E=E 3+= ------~~~~ cº------F >-r *--------------. —E--- +c-FLE ºfflº- --~~~~-. *------------ >- -- T-T_– :- -- * * --> -----------------E-º-T " - --> FI- - L - - >-------Tºtº ºt- - d *::=Eğ. = -- º B === º: :: º #E=º::=# = --~~~ - |; -*=== * -- * ºt," ... . . . tº -- * #.'º-º-º-º-º: F --~~ sº = ſum ºftiºs= ºf: ºftº: D far tº ſºlº tºº Priºr Hº tº ----- ===Hºº EEli Hill;tº-cº. jºſ, § #. # | # | intº º ' ' ', # --> #|## | # | | # jºjº #| ||lſº º | º-º #zºs == | § | # | ######## ##| † #| º #Eß zººs º | fººt; º t # * : * : * illu ... tº: -- ſ t - º º - E={# | # | º ºil-ºº: Ş º } ſ ''{I} | |||ſ ºn ºn a *.*.*. º S- ar(ſº +12% Zºº; lº ºš § Et-ɺ liºtºujiltºniº". - . . . #|| º --ſº- º ºRº | rSºś |ijºji; ºf # i *...* w ºw º Rºsº §§ º | - - 2 ºzººlºs S c &: ºssº ! tº º sº | |- sº ! º º Aº Aº º º ºw ºw. " ". ~. ºº::$º: Sºº- ſº- * . . . . . º * ſ º aſ a lº §§ º, ſ * . . # Fºs f §§f Soº ">-S: º #sºsºsºft . t ºf: |IHiſ .: Sº § - ! ºr ſº ºº: És 3. º: s: º º * || || || £º: §§§ §§§8.4%% v. 1 º: dº iſſºt sºas Sassº. ººº- * 5 {j º: §§: E §§§ a Eß: º *:::::==<= ɺ: º #.º: §:### Sºğ. S; +ºğº- ºº:: * : 2. E2-P, º -> Eº §: ** غ: É #####s *- . GOOD SA #3% źs º º º Sºsº: • & *::::: #! º, % ſ | :#sº š E- as **, |ſº 2.52% ... . º.º. º sº §% % &% #2%% 33% ºftº: É%% 2:2:2° - •º A. e. - %%ſº 3.4% * Z º -> :=º * *:42:5 É% º 2, 22.2 jº ºfflº §ºšº #Sºs ** 2. Ç/2 % *: º. A Zºº, , , 2/2 - %2%=- sº sºsºs:4%% % % *=s=====sº 22– Ž * : . . .” --S 5 §º: º º, =S$3%% (ſ 2.2% M A PITALIN EIOSIPLT ALT 1. The GOOD SAMARITAN HOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner of Sixth and Lock streets. pointments of a First-class Hospital. It is handsomely furnished throughout, and is provided with all the necessary ap- Porticoes, with commanding views, surround the whole house, and wide halls and abundant windows secure that full and free ventilation which is so essential to health and comfort. Service is furnished by the SISTERS OF CHARITY, Under the Superintendence of the well-known SISTER ANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. The regular Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each Professor presiding over his own especial department. Patients may, however, select from the regular profession of the city any physician of their choice. The GOOD SAMARITAN HOSPITA), presents extra inducements to Invalids throughout the State as a safe and quiet asylum in any case of protracted illness, or in cases, more particularly, requiring Surgical Operation, where some stay is necessary in after treatment. Rooms vary in price, according to the character of appointments necessary and service required, ranging, in general terms, between $3.00 and $15.00 per week. service. tº Address, SISTEER ANTHON.Y., This includes, of course, the diet list, and every demand of FIospital of the Good Samaritan, Corner of Siacth and Lock Sts., Cincinnati. Ohio. ROBT CLARKE & C0. William Autenrieth, PUBLISHERS, No. 71 WEST s][XTH sº DEREET, Hºlºhim ... N0, 65. WEST FOURTH STREET, MANUFACTURER OF AND DEALER IN *:::::::::::::::::::::::"I'll III IIHITI'll III/III, i ** § &nglish, 3merican and french Abdominal Supporters, Trusses, ºrcº P60A's. maroor shops. 'Paying particular attention to this branch of SPINAL APPARATUS, ETſ their business, they are enabled to execute all orders on the shortest notice, and at the most reasonable rates. Their facilities for the impor- Keep-constantly on hand a full variety of tation of FOREIGN BOOKS, THE PROCEED- INGS OF SOCIETIES and HOSPITAL RE- 4 tº PORTS are unsurpassed, and any orders en- Metalie and Rubber syringes, trusted to their care will be filled promptly, and at the lowest rates. Subscriptions received for FOREIGN and | BETWEEY WALWUT Ass WINE, ; i Stormtaleh Pumps, Ete. AMERICAN PERIODICALS. STQC(K556S FOR WABDCOSE WEUNS, All the New Publications received as soon &S issued. | Special attention given to the fitting of Apparatus for Deformities. Tetters of Inquiry will receive our prompt º 40 andful attention. •º tº a de : Gº Agent for DR. L. A. BABCOCK'S Catalogues furnished gratis on application. ROBERT CLARKE & Co., Silver Uterine Supperter, lºwhººlin,hºlm, mºnºliin PRINTERS AND BLANK BOOK MANUFACTURERS, -ALSO– DR. AHL's POROUS FELT SPLINTs, -ALSO- 2ealers in Zaze,_Medicač, Zheožogical, : School, azed.Mºscellaneous Zºooºs, D A. Y. * S S E LIN T S G5 West Fourth street, -AND- CINCINNArr, o. C - S. W. Elliott’s Saddle-bags |||||||||}|| MM|| ||M|| SAML. P. THOMAS 167. EAST 34 TLL-ST., NEW YOIRI, By Special Appointment Electrical Instrument Makers tº the New York State Hospital for Nervous Diseases, MAN UFACTURERS OF PORTABLE ELECTRO-MAGNETIC MACHINES, Portable Galwamic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, 1870, and May 30th, 1871. These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery I'luid. |M|| ||V|-|| ||||||| IPERMANIENT BATTERIEs, For Hospitals and General Practitioners, IET IIECTIE-2,OTDIES. For Eye, Ear, Larynx, Nose, Uterus, Vagina, Bladder, Rec- tum, Feet, Phrenic and Sympathetic Nerves, Elec. trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. -->O->O-c- IEXTRA tº TS FR0 yr TH F O PIN TON'S OF TII E. My OST EMI IN ENT MEM t; ERS ºu F Tºuſ: PItty FESS to N. WM. A. II AMIMOND, Prof. of Diseases of the Mind and Nervous System, Hellevue Hospital, says: “Notii ING cAN EXCEED TII E EFFICIENCY AND CONVENIENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” We are authorized by Prof. IIammond to announce ern- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- proved and re-modified Instruments made by our Company. * M EREDITII CLY \l ER, M. D., 1’rof. of Diseases of the Neº- vous System and of the Mind, &c., &c.—“l consider their Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prof. of Surgery, St. Louis:–“ In neat- ness, compactness and efficacy, they can not be excelled.” A LFR E.D. C. G. ARRATT, M. D., Boston :-"In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” Simi ar Testimonials have been received from JOHN J. CRANE, M. D., Vice-Pres. Med. Iłoard, Bellevue IIospital; A LEX. B. MOTT, Prof. of Surgery; A. MUR RAY, M. D.; CHAS. E. B.I.UMENTIIA L, M. D.; E. C. SEGUIN, MI. ix.; A LLEN MAYN A R D, M. D., Cleveland, O.; Dr. C. WANN i E, Waynesburg, Pa.; Dr. JOI) N KlNG, Cincinnati; Dr. JAMES KELLY, Florence, (); Dr. JO11N BECKER, Brighton, Iowa; lor. G. It SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes- b irre, Pa.; JOHN J. CALD WELL, M. D., Brooklyn, and In any other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an Llectrical Instruinent for medical purposes. J CALL OR SEND FOR CIRCULAR AND PRICE LIST. * Can be | DEALER IN English, French and Scotch GOODs, 34 West Fourth Street, ("A.W.’6”.A.W.Wº Z"A. FOSTER’s N 2. Sºº "a º ſ º U.Nº º IF_A_TIENT Willitial Are furnished to Officers and Soldiers on Government a CCount. I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others new in use. For the truth of this assertion, I would respect fully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs— my choice in a limb – why I commenced to manufacture them—suggestions to those sut- fering from loss of limbs—is it best to have an artificial limb–why is it that some get artificial limbs and do nºt wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb. etc., etc. All communications should be addressed to JAMES A. FOSTETR a 911 Chestnut Streets. Philadelphin, Pa. No. 60 West § U) šč. § tº § - § {ſ} § O § Nº. Fourth street. Cincinnati, Ohio, or 172 Jeſ. ferson Avenue, ixeiroit, Miche gºssmºs 'uºmº O' D C R L E s s A N ID PA. L.A.T A. E L E. In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERs & BARTLETT, of Portland, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. Our notice was first attracted to this Oil by several leading physicians of the city, who bad found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. - Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- ſectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Itachilic Affections, in Chronic Rheumalism, &c. - The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. - We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. \ - JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. DIVIDED MEDICINES, PREPARED BY The Divided Medicine Comy, CINCINNATI, OHIO. - { . +. - The Company have the honor of bringing to the notice of the Profession, this NEW AND ExcEEDINGLY PRACTICAL METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. The Divided Medicines are prepared by FREDERICK KRAUS, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several squarES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MORE. . The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every square will consequently contain accurately measured quantities. But not only SolubLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINES. A' 2 This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, ! ; ; , ºo, and even lobo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. . -- . . Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE TO SPOIL BY ANY LENGTH OF TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. • . Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calls with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. For samples, Price Lists, and Agencies, address The Divided Medicine Coe ‘p EOx: 2ess, Or FRFDERICK KRAUS, Chemist and Druggist, Walnut Hills, Cincinnati, O. MIt. FREDERICK KRAUs: CINCINNATI, renº, 15, 1871. Dear Sir—The specimens of your “ Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity opecified in each, viz: - SU LP II: M () ſº PH II....................... % grain in each square. ARSEN: ACID.......................... 1-20 grain in each square. ** (; H IN INI .......................] * * * * & tº CALOMEL 34 “ “ & 4 * COPPElt ........................% & 6 ResPEctfully Yours, E. S. WAYNE, Analytic Chemist FEB. 3, 1872.] O RIG IN A L A RTI C L E S. —sº-º-º- SOME MEDICO-H, EGAI, QUESTEONS IN THE waTsox-shºrt YoCK MURDER CASE. BY Roberts BARTHoLow, M. D. The trial of Watson for the murder of Shryock which has recently been concluded at Evansville, Indiana, involves some medico-legal questions of great im- portance. During the course of this investigation, there have occurred amongst the medical witnesses, those marked differences of opinion with which the public now, unfortuna'ely, are only too familiar. These un- scemly differences result from various causes. Medical men summoned to testify to facts, and as experts, differ widely in their powers of observation, in their reasoning faculties, and in their knowledge of the special questions submitted to their decision. Actuated by a foolish vanity, some physicians in the witness box are led to differ on matters of fact and opinion, because in agree- ing they would appear to be no wiser than their col- leagues. Nothing seems to be more grateful to such weak minds, than this mode of asserting their superiority. Moreover, professional prejudices frequently intervene to bias their opinions. They are sure to differ with an opponent or a professional rival. It follows from these facts that courts look with suspicion on expert testimony, and lawyers make use of it to confuse, rather than en- lighten juries. The Watson-Shryock murder case fur- nishes us no exception to this customary conduct of medical experts, and the acquiual of Watson, the accused, is largely due to the confusion in which they involved simple matters of fact. Shryock was wounded on the 20th of October, 1871, by a pistol ball fired by W son. The ball entered the right lateral plane of the body in the intercostal space between the ninth and tenth ribs. Dr. M. J. Bray, who it appears is a Professor of Surgery in the Evansville Medical College, was called upon to attend Shryock. He testified that he “discovered a bullet wound in his right side,” that “the bullet hit the ninth rib and passed between the ninth and tenth ribs.” Notwithstanding the strong probability that a bullet passing between the ninth and tenth ribs would involve the liver, we find this surgeon practising the enormity of probing the wound. With a disregard of the consequences of such manipulation, amazirg even in a novice, but most prehensible in a professed surgeon we find that he inserted a probe five or six inches into the Wound, and traced the ball as far as he could. , That he really did probe this wound of the liver ap- Pears in concurrent testimony. Dr. B. J. Day who TIE-L IEI, C T , T INTT C. 49 attended with Dr. Bray also “probed the wound.” Dr. Davidson, an intelligent young physician who was pres- ent, testifies that Dr. Bray “probed the wound down- ward and inwardly.” Any intelligent physican can after such statements estimate at their true value, the opinions of such an expert as Prof. Bray. It is true“he thought none of the viscera were injured,” although “he noticed jaundice about a week after the wound was inflicted.” Dr. Bray and Dr. Day also testified that Shryock had peritonitis in a few days after the in- jury, and Dr. Day with an insight which appears akin to “second sight” discovered two abscesses which appeared and disappeared in a miraculous manner under the touch of this medical magician. Notwith- standing this, Shryock became weaker, and although Dr. Day considered him in danger, he was placed on a steam- boat to be transported to Cincinnati. When he arrived on the boat Shryock appeared to a witness to be “so weak that he might die at any moment.” It appears further that he died en route, at the Louisville wharf on Sunday, the 15th of December. He was interred at the Wesleyan Cemetery near Cincinnati. The body was exhumed on the 8th of January by authority of the Coroner, and an autopsy was made by Dr. M. T. Carey. Captain Hargrave, Prosecuting Attorney of Vander- burgh County, Dr. H. M. Harvey of Evansville, Dr. R. H. Johnson of Cincinnati, and the writer were present at the autopsy. Notwithstanding the body of Shryock had lain in the ground twenty days, it was quite well preserved, and in a satisfactory condition for examina- tion. The eyes were much sunken, and there was a greenish-gray discoloration of the abdominal walls, but otherwise no obvious change had occurred. “A small oval cicatrix” in the words of Dr Carey “was found on the right side of the chest at the lower margin of the ninth rib, and six and a half inches to the right of the median line of the body.” Dr. Bray, who appeared to be extremely anxieus that none of the abdominal or- gans should prove to be injured by the ball, in his ex- planations to the jury, fixed the position of the wound of entrance, much further forward toward the median line of the body, than the situation of the cicatrix warranted. The abdominal organs although much dis- colored were in a satisfactory state of preservation, and it was quite easy to discover any lesions which the en- trance of the ball may have produced. The evidences of general peritonitis were conclusive. The intestines were glued together by inflammatory exudation and numerous fibrinous bands stretched across from the parietal to the visceral peritoneum. In separating some of these bands attached to the descending colon, the bowel gave way and perfectly normal feces escaped. Dr. Carey, in his report makes the extraordinary state- ment that this fecal matter was found external to the descending colon, and referring to two points of per- foration in the bowel leaves it to be inferred that this escape of feces was ante mortem. That he intends this inference to be made, is evident because he immediately #50 [FEB. 3, 1872. T H. H. C.I.I.INI c. alludes to a collection of “about sixteen ounces of yellow fluid having the color of feces in the right hypochondrium.” A perforation in the intestine, due to an ulcerative process, escape of fecal matter, and subsequent peritomitis, would form a theory to account for the death, and in fact this theory was made use of by an expert called for the defense. As there was no evidence of intestinal lesion, as the feces were not visible until Dr. Carey used his knife to separate the adhesions, and as the feces which then escaped were normal, the conclusion is irresistable that it was the post-mortem dis- section and not disease that had caused perforation of the intestine. The most remarkable lesion developed at the autopsy was the sero-purulent collection in the right hypochon- drium, alluded to above. This fluid was limited to this situation by adhesions between the parietal and hepatic peritoneum, and it was bounded above by the lower concave surface of the diaphragm, and below, by the upper convex surface of the liver. An excavation about one-fourth of an inch in depth at the deepest part, existed in the right lobe of the liver and formed the lower boundary of the sero-purulent collection. A cicatrix was discovered on this part of the liver. Dr. Cary who seems most desirous not to state facts which may bear an interpretation unfavorable to the accused, mildly expresses himself as follows: “Upon the anterior and inferior margin of the right lobe of the liver there was an induration and a puckered condition of the part, which looked somewhat like a cicatrix.” He has nothing to say in regard to the re- lation which the external wound bore to the cicatrix on the surface of the liver, notwithstanding he was coduct- ing a medico-legal investigation. Dr. H. M. Harvey of Evansville, a very intelligent and accurate physician who was present at the autopsy, testified that “the cicatrix on the liver corresponded with the external scar,” and this he ascertained most positively by passing a probe through the external wound. I saw this ex- periment made and also testified positively to the fact. A Dr. Johnson, of Cincinnati who admitted that he had been physician to Watson's family and was em- ployed by Watson's brother to attend the autopsy, testified that the external wound was not in relation to the cicatrix on the liver—but Dr. Johnson made many very remarkable assertions in the course of his examina- tion. If nothing more than a cicatrix indicating injury to the liver had been discovered, doubts might have arisen as to cause of it, but immediately in connection with the external cicatrix there was found a perfora- tion extending entirely through the right lobe of the liver. This canal was of a grayish-brown color, perfectly distinct from the rest of the liver substance as regards appearance, and contained within it some partly fluid and partly solid matter. Dr. Harvey testified that this canal was about the size of an ordinary lead pencil, which corresponds with my own observation. The eapert Dr. Johnson and Dr. Cary did not see this. Dr. Johnson testified in Court that this perforation had no existence, and Dr. Cary does not allude to it in his report to the coroner although it was laid open and commented on during the autopsy. Some concretions of very recent formation were found in the gall bladder. That these concretions were recent is evident from the following facts: they were very irregular in outline and very soft and friable. When several old biliary concretions are contained in the gall bladder, they are firmer, have smooth facets and are known, hence, as “articulating.” The gall bladder itself undergoes changes due to the long continued irritation of these concretions; the mucous membrane becomes thickened, and the organ contracts inflammatory adhesions to the surrounding parts. These changes are slow in progress and are not manifested by obvious objective symptoms; hence, biliary colic is the only conclusive evidence usually obtainable of the existence of these bodies. (Thudicum, p. 188. Trousseau, Vol. III. p. 218.) . As there were no lesions of the gall bladder whatever, as the concretions were soft and friable, and as there had been no symptoms of hepatic colic, it is clear the “gali stones found had been formed very recently.” Indeed there can be no doubt, that their formation was the direct product of the changes in the constitution of the bile wrought by the injury of the liver. The confident Dr. Johnson, affirmed that “the presence of these gall stones would seriously affect the health because no bile could be received into the gall bladder”—a remark which indicates that he is not aware that the gall bladder is not essential, that it is only a receptacle for the surplus bile, and that as the hepatic duct com- municates with the common duct, the bile will continue to flow into the intestine even when the gall bladder is permanently occluded. But Dr. Johnson acted as an expert whose business it was to defend the accused. The ball which passed through the liver was found “upon the anterior surface of the left kidney,” directly on a line with the external wound and the perforation through the liver. In order to avoid this import- ant organ, the liver, Dr. Bray in his testimony made the ball drop down into the cavity from the rectus muscle, and Dr. Johnson caused it to be deflected by the ninth rib and could not be induced to believe that it had entered the abdomen at all, until it was found on the left kidney, when he was put in the de- plorable position of having no theory to explain its presence. Several of the principal physicians of E ans- ville, Dr. S. W. Thompson, Dr. J. M. Myler, and, Dr. De Bruler examined as experts, testified that A ball entering the right lateral plane of the body b tween the ninth and tenth ribs, and reaching the 'eft idney, would necessarily pass through the right bbe of the liver. - - - I should not fail to notice the attempt made to ex- plain the cicatrix on the right lobe of the liver by an assumption that it was syphilitic in origin. Evidence was introduced at the trial to show that Shryock had FEB. 3, 1872.] T TED TEB C T , T TNT I C . 5} been syphilized, but there were no external or internal manifestations of syphiloma found at the autopsy. The cicatrix on the liver presented none of the characters significant of this condition and the rest of the organ not affected by the ball in its passage, was free from suspicion of syphiloma (Virchow, Syphilis der Leber). As the defense also maintained a theory that Shryock had died of phthisis and not of the gunshot wound, it is very important to examine with some attention the condition of the lungs. Dr. Thompson testified that Shryock was discharged from the army in 1863 on ac- count of consumption, but admitted that there was not found sufficient disease of the lungs to cause death. Even the confident Dr. Johnson admitted that, although “the lungs were very much consolidated by calcareous matter, consumption had nothing to do with the death.” Dr. Carey reports that “the upper lobes of the lungs were comparatively healthy except they contained some cretaceous tubercles.” He states, however, that “the lower lobes of both lungs were found in a state of carnification and contained small tubercular cavities”—— expressions which indicate clearly enough that Dr. Carey is not informed in regard to the recent pathological views on these points. The “state of carnification,” there can be no doubt, was simply pneumonia, and the cavity which was found at the base of the right lung, was formed in anticipation of a discharge through the lungs of the purulent collection on the other side of the diaphragm. It is now perfectly well known that ab- scesses of the liver frequently discharge through the lung, that adhesions form between the pulmonary and diaphragmal pleura, and that an inflammatory process is set up in the lung to make a passage way to the bron- chi. (On this point the reader may consult any work on the liver—Frerichs, Murchison or any modern work on Practice. Also Rokitansky, vol. 2, p. 108). Having thus set forth the reasons for believing that the ball which entered Shryock's body between the ninth and tenth ribs, wounded the liver and peritoneum, it remains to inquire whether the lesions found were attributable to this cause, and whether death was the result of the injury. On these points we find some extraordinary testimony by witnesses to fact and by the experts. Dr. Bray did not think the ball injured Shryock, that it could not have gone through the thickest part of the liver, and that death would have ensued in a few hours if this organ had been wounded. Dr. Day did not think the sero-purulent collection in the right hypochondrium bore any relation to the wound; the ball may have “aggravated” but did not cause it, and yet he admits that the abscesses right and left in regard to which he testified, followed the injury. Dr. Johnson testified that a wound of the thickest part of the liver would prove fatal by hemorrhage in from twelve to twenty- four hours. 9" the other hand, Dr. De Bruler, who is an accom- Plished physician, testified that a wound of the liver is not necessarily fatal, but that “a ball passing through the liver and lodging in the left kidney would produce a serious injury.” Dr. H. M. Harvey, whose testimony was a model of clearness and scientific accuracy, said that the ball passed through the thickest part of the liver, that the position of this organ varies somewhat with inspiration and expiration, that a gunshot wound of the liver may prove immediately fatal by hemorrhage and shock, that, if the patient recover from the imme- diate effect of the injury, he may succumb to the results of the inflammatory process. As it is impossible to reconcile the conflicting views of the experts, authorities must be appealed to in order to ascertain whose opinions are in accordance with existing knowledge. Are wounds of the thickest part of the liver neces- sarily immediately fatal 2 M. Verneuil has recently reported a case in which a revolver ball passed through the greatest diameter of the liver, without causing death, but peritonitis did not follow the injury. In Circular No. 3 for 1871, I find three cases—Dr. Whitehead's, Dr. McKee's and Dr. Hassig's— which the right lobe of the liver at its greatest diameter was wounded, and yet recovery ensued. In these instances, free diseharge took place from the external wound and gem- eral peritonitis did not follow. Severe shock followed immediately on the reception of the wound, and in Dr. McKee's case, a condition of collapse, but the patients emerged from this, and not being subjected to the de- structive changes consequent on general peritonitis and hepatitis, recovered. Hamilton (p. 363) thus speaks of wounds of the liver : “When a ball has penetrated this organ, death gener- ally ensues in a very few hours from internal hemorrhage; and in the large majority of cases, when owing to the more superficial course of the missile, a fatal hemorrhage does not occur, death follows in a few days from the supervention of inflammation both in the substance of the liver and in the peritoneum. Occasionally, how- ever, the patient survives a long time, or makes a com- plete recovery.” McLeod (p. 256), whose book is based on the expe- rience of the Crimean war, makes the following obser- vations: “Balls entering the liver, kidneys, or spleen, are well known to be usually mortal, although excep- tional cases are not rare. The collapse is generally very severe.” If some hemorrhage, or the effusion of any of the secretions, as bile * * * follow the injury, then the collapse will not only be severe but continue. The inflammation which is so certain to occur in the peritoneum requires very careful watching, as it often sets in very slowly and deceptively.” Larrey (Tome II, p. 420,) speaking of wounds of the liver, remarks that if extravasation of biliary matters takes place in the peritoneal cavity, the wound is necessarily fatal. He gives two instances of recovery from gunshot injury of the liver, but in these cases, the 52 [FEB. 3, 1872. TIE-T ED CT, T N T C. extravasated blood and biliary matters found vent through the external wound. Ballingall (p. 347) after alluding to the great mortality of gunshot wounds of the liver, thus describes a condition of things exactly like that found in the body of Shryock: “When the patient survives so long as to admit of an adhesion taking place between the surface of the liver and the abdomen contiguous to the wound, the matter which subsequently forms is precluded from access to the ab- dominal cavity, and the case is then assimilated to one of abscess of the liver.” Guthrie (p. 582,) sums up in a few sentences the results of wounds of the liver. “Wounds and injuries of the liver whether incised or penetrating, occurring from blows or from musket balls, are very serious, although not necessarily fatal. Some few persons recover altogether; some few with more or less of permanent disability. The remainder die during the first or inflammatory stage; or in the secondary one which follows from the twelfth or fourteenth day after the primary symptoms have in some measure sub- sided.” Hennen (p. 329,) says, “The wounds of the fixed viscera of the abdom.en though highly dangerous are not necessarily mortal: * * All deep wounds of the spleen, liver, or kidney, are almost immediately fatal from hemorrhage; some instances however occur, where even severe injuries are survived.” Hennen gives (p. 340) a remarkable instance of recovery in which the ball fractured the eighth and ninth ribs and passed through the greatest diameter of the right lobe of the liver. From these military authorities, the highest to which we can refer on questions connected with gun- shot wounds the following conclusions may be deduced: Gunshot wounds of the liver are not necessarily fatal. If the patient survive the shock of the injury, he may live a variable period of time. - Wounds of the liver that do not prove immediately fatal may cause death by secondary inflammation. Abscesses connected with the liver by limiting in- flammation, and general peritonitis are common results of wounds of the liver, It follows as a corollary from these conclusions that although Shryock's wound of the liver did not immedi- ately prove fatal, his death eventually was due to the inflammation which ensued, and was brought about in the mode indicated by the authorities on this sub- ject. Authorities referred to in the text: TIIUDICUM.—A Treatise on Gall stones: Chemistry, Pathology and Treatment. London, 1863. TROUSSEAU.—Clinique Médicale de L’Hotel Dieu de Paris Tome 3me Paris, 1865. VIRCHOW.--Die krankhaften Geschwälste. Zweiter Band, Berlin, 1865. American Journal of the Medical Sciences, January, 1872, p. 263. Their Churchill, Circular No. 3, Surgeon General's Office, 1871. HAMILTON.—Military Surgery, New York, 1865. M. LEOD.—Surgery of the Crimean War. Churchill, London, 1858. LARREY.-Clinique Chirurgicale Tome. deaux. Paris, 1829. - BALLINGALL-Outlines of Military Surgery. Fifth Edition, Edinburgh, 1855. - GUTHRIE.—Commentaries on the Surgery of the War. Sixth Edition, London, 1855. HENNEN.—Principles of Military Surgery, First Am. Ed., Phil., I830. —sº- e -º--- o P HT HI A L NIH A N E O N A T G R U ºf . BY PROF. SEELY. A Clinical Lecture at the Dispensary of the Medical College of Ohio. GENTLEMEN : The first case I beg to call your attention to is this little child, three weeks old. I open the eyelids and you see from one eye the matter streaming out ; in the other you might see it resting in the lower cul-de-sac. We have before us a case of the so-called ophthalmia neonatorum. What is the disease? From the physical characters certainly all would say a purulent iuflammation of the conjunctiva. I have already tried to impress on yºur minds some points in differential diagnosis in ophthalmic troubles. in these little people, while the tendency of mucous inflammations is towards the purulent form, yet it is by no means absolutely necessary for them all to assume it, for we sometimes find but a catarrhal form with only a muco-purulent discharge, and this may be slight. A simple statement of such a fact may be sufficient to afford some comfort when you are brought into contact with irritated eyes in your obstetric practice. Let us see what the symptoms are which should attract your attention. If in from twelve hours to a week or two after birth, you find the eyelashes matted together or the eyes tearing a good deal, and on depressing the lower lids the conjunctiva looks red and swollen You have sufficient cause for suspecting the commencement of an inflammation. If these symptoms appear in the first three days you *- would be warranted in regarding them as the beginning of what is most strictly termed ophthalmia neonatorum, purulent conjunctivitis in new born children. Aetiology. Almost any irritation of so delicate a membrane may produce a purulent inflammation, and yet there are certain irritants to which the eyes of the new born |are especically liable. FEB. 3, 1872.] TIH. H. C.L.INI c. 53 The child in its passage through the vagina comes in contact with whatever secretions may be there, and particles from these may be the exciting cause. These vaginal discharges are probably the most fre- quent cause of this disease, and the cases brought before you have only too frequently such an origin. I have given the mother of the child a prescription for blenorrhagia, which she says she was suffering from when the child was born. So in this case we probably need look no further for a cause, as you all know the virulence of the gonorrheal matter. Inoculation, then, is the most fruitful source of ophthalmia neonatorum. But do not be too ready to infer such an origin, as carelessness in cleansing the child, and caring for it by exposing the eyes to too bright a light, allowing the cold air to strike, etc., may produce the character of inflammation. For your therapeutics it matters little what the cause may be. If you have formed suspicions or not, you give the necessary precautions about the hands being clean when the child’s eyes are attended to, and that all the cleansing apparatus be absolutely clean and used only for the child. In this way you protect those about and also prevent reinoculation if the mother has gonorrhea. Gonorrheal ophthalmia is only produced by some of the particles of matter coming in contact with the conjunctiva, and it is on this account that we caution, so strongly, patients with gonorrhea against getting in any way the matter into the eyes. Prognosis. The prognosis will depend on the stage in which you see the case. Seen in the premonitory stage it is always good, for the congestion can almost always be removed by very simple treatment; if not seen till the eyelids are more or less thickened, and discharging pus it is still good; but if the cornea shows any signs of being involved the prognosis must be guarded. Treatment. In the first stage a weak astringent, such as half a grain of zinc or nitrate of silver to the oz. of water, or even a weak solution of the sulphate of morphia (gr. 3 aq 3i.) will suffice to relieve all the difficulty as a rule, if uscd every two or three hours. If the second stage has come on and there is more or less swelling of the lids and a purulent discharge, the indispensable condition is just what I insisted upon so strongly while talking to you at my Thursday’s clinic, on discharges from the ear, cleanliness. Every few minutes the matter must be wiped away with a soft rag, and once every fifteen or twenty min- utes the eyelids should be gently opened and some warm Water allowed to run from the end of the rag over the ball to wash the accumulated matter from the con- junctiva. This can all be done without waking the child. Local applications. After you have thoroughly cleansed the eyes, in the milder forms when the corneas are clear, and the lids but little thickened I recommend you to use, especially if you are not skillful in everting eyelids or can only see your patient once or twice a week, a weak solution of nitrate of silver gr. 3 or i. to 3i, a drop or two to be placed between the lids every half hour during the day if the solution is gr. 3, every hour or every two hours if it is gr. i. This plan succeeds well in a large number of cases and can be carried out by the mother or nurse. If there is a good deal of thickening of the conjunctiva, the papillae promfinent, your surest plan is to see the patient every day, place its head between your knees, as I do here, by way of illustration, evert the lids, the upper and lower at the same time or separately as you are able, then brush them with a strong solution of the nitrate, a ten or fifteen grain solution of the pure, or a twenty or thirty of the mitigated, washing the solution off immediately with salt and water, and finally with pure water. Such an application as this once a day is sufficient; using in the mean time, a collyrium of atro- pine or morphine (gr. 3 aq. 3i), two or three drops of which are to be gotten thoroughly into the eye three times a day. I have never seen any cases where the diphtheritic element was insufficient to modify the plans of treatment marked out, necessitating the care insisted upon in purulent ophthalmic of adults, Pure diphtheritic inflammation is never met with in new born infants, but some of its characters are : For example, we sometimes find the lids pretty hard and hot, with a palish conjunctiva secreting a thin dis- charge of a filmy character that quickly covers the surface of the membrane. Weaker in such cases recom- mends internally a small quantity of calomel three times a day and the rubbing on the brow of a little mercurial ointment, discontinuing this treatment imme- diately the purulent discharge thoroughly begins (See vol. 1, part 1, 2d Ed. Maladies des Yeux). The all im- portant question in this is how to act when there is an affection of the cornea. Your attention must be con- tinually directed to the state of the membrane, for in complications on its part lie the dangers. Here we want to get rid of the cause of the corneal affection, viz., the swelled lids and chemosed bulbous conjunctiva, as rapidly as possible, hence, we continue the applications and soothing wash : making use of extreme care if the lids are everted. If there is an ulcer a paracentesis of the anterior chamber should be made to relieve the intra-ocular tension. If a perforation has occurred, and a prolapse of the iris exists, it should be snipped off. The perforation may be large and the eye become staphylomatous, and require amputation. The narration of a case that recently presented itself at my private rooms, will be sufficient to put you on your guard in the after treatment of eyes left with a corneal cicatrix. - 54 [FEB. 3, 1872. TIEI IED CT, I. TNT I C - A girl of 13, had, while a child, some attacks of cir- cumscribed keratitis, from which resulted rather a prom- inent corneal cicatrix. No special attention was paid to the eye, until the parents noticed an increase in its size. The cornea and pericorneal tissue had yielded, the anterior chamber had increased in size and when I saw the case, the papilla was cupped and the eye was blind from glaucoma. I have put you on your guard what are the objective symptoms to be loëked for, as in little children, no subjective ones are to be expected. Every eye that presents a corneal cicatrix, and espec- ially an adherent one, the so-called leucoma adherems, should be looked after. Now if in such an eye, you at any time detect an in- crease in the intra-ocular tension, an iridectomy should be insisted upon at once. We had long been aware of tle danger in such cases, but it remained for Graefe, the great teacher whom all mourn, to put in a clear light the exact relation between cause and effect, and to show the steps that lead from one to the other. —º-e-º-- A tropia as an Antidote to GPium. BY W. L. BUECHNER, M. D. Yorngstown, Ohio, Mrs. H. H., aged 33 years, had been suffering for a week with severe facial neuralgia. January 24, she took a large dose of morphia; about four hours afterwards her condition alarmed her friends and I was sent for. On my arrival I found her lips and face purple, no pulse at the wrist, pulsation of heart hardly perceptible, respirations six per minute, pupils contracted to a small point, surface very cold. I pro- nounced the case hopeless, but recalling a case reported where the patient was saved by the hypodermic use of atropia, I concluded to give it a trial. I injected 1–48 (one-forty-eighth) grain of Atrop. Sulph. In five min- utes the breathing became better, the heart's activity more vigorous, the pupils dilated slightly ; in half an hour I repeated the dose (1–48th grain) and the case improved rapidly; in about forty minutes from inject- ing the first dose consciousness partially returned, and in about an hour, the effects of the morphia had entirely disappeared. HospitaL CAPACITY IN VIENNA.—The number of free beds in all the hospitals of Vienna is 219. There is one bed, thus, for every 144 inhabitants. Paris has one for every 151, London one for every 600 inhabitants. The mortality rate of the two extreme cities, however, differs materially. In London 22.4 in a thousand die every year; in Vienna 81.4. * T H E s U R G E R Y or w Art. BY PROF. PIRogoFF. Being an Abstract of an Eatensive Review of the Author's Report on the Military Service ºf the late Franco-Ger- manic War. From the Allgemeine Miltārārztlichle Zeitung, Vienna, Dec. 24, 1871. The fourth, the most extensive and important section of this interesting volume, takes into consideration all the essential questions concerning the surgery of war. The author begins with the general treatment of gun- shot wounds. Up to fifteen years ago all surgeons were united in the belief that antiphlogosis, in the form of ice, venesection, low diet, was a necessity in the treat- ment of these wounds. This opinion prevails now no longer. Even Esmarch, the enthusiast on the sulject of ice, seems to have modified his views for in the Ber- lin lazareths under his direction nothing is to be seen of this treatment. The injuries of the various parts of the body observed are next taken up. Concerning penetrating wounds of the head he states that be only saw ten in all the Seventy lazareths and in these there had been adopted neither an energetic antiphlogosis nor any operative proceedure. The results in the treatment of these wounds are now as form- erly discouraging: they died also without the operation of trephining. Most brilliant was the result in the cases of penetrating Chest wounds treated on the expectant plan. In each of the 70 lazareths were observed 5 or 10 cases of re- covery from these formerly considered fatal wounds. The cause of these favorable results, however, is not to be ascribed to treatment alone. The small size and the . form of the chassepot projectile, whereby passage through the intercostal spaces without injury to the ribs might he effected, should also be considered: in those cases where the ribs were splintered the result was, in this war, unfavorable. The admirable construc- tion of the German hospitals was an important element in securing good results in all cases. In eight cases paracentesis was followed by happy results; in two cases recovery ensued after hernia of the Hung. Of those wounded in the abdomen but five were found alive. One of these was struck in the right hip joint by a ball which remained concealed. There was dis- charged from the wound at first, hairs, later bile, and then cough ensued with expectoration of bile. In two others wounded in the abdomen, the ball passed through the convex surface of the liver. Finally there were two with wounds of the large intestine. All these were already out of danger. FEB. 3, 1872.] T TH. H. CT, INTI c. 55 The difference between the orifices of entrance and exit could not be distinguished in this as in other Wars: both openings presented the same appearance ; often, thus, the opportunity was presented of observing the healing of gunshot wounds without suppuration. The “Debridement préventure” [enlargement of wounds] of the French was nowhere adopted, on the other hand surgeons had fallen into the opposite extreme, there was fear of the often so efficacious dilatation of the wound. Salves and cerates were seldom encountered, in their place very frequently dilute solutions of carbolic acid; the mixture of the acid with oil is not so suitable. The author acknowledges himself an advocate of the panspermist theory and accepts a double infection, either by ferments developed from the constituents of pus and decomposed blood or by ferments which have penetrated from the external air. As to the closure of gunshot wounds he can say little good of this method and believes that the use of the lead plates of Burggräve and the plaster and caoutchouc envelopments of Leudörfer may be of injury. On the other hand he considers the method of Guerin the treatment by aspiration, as worthy of further trial. Borow's plan of exposing the wound to the air without any bandage whatever is reprehensi- ble because it does not sufficiently support the soft parts in the vicinity of the wound, does not exercise upon them antiphlogistic pressure and does not guard the wound itself against injury. The author is a great friend, however, of free drainage and irrigation. The use of charpie, of gauze bandages and of oakum “marine lint” which he found in the different hospitals is desig- nated a progress in the treatment of gunshot wounds. The teachings of Bouchet and Larrey as to the value of early amputation were accepted doctrines in military surgery thirty-five years ago; the authority of Dupuytren contributed no little to the sustentation of this view: It availed as a dogma in gunshot fractures to amputate as quickly as possible: should time be allowed to inter- vene more lives would be lost than limbs saved. The author himself long sanctioned this doctrine, taught it and widely extended it, and there are still many sur- geons who maintain it firmly. But the great majority of surgeons have retreated from this opinion and the reasons of their retraction are: 1—The Introduction of Statistics in Surgery; 2—The Invention and Extension of Immovable Ban- dages; - * 3—The Adoption of the Conservative Operations. Malgaigne it was who first showed in 1841 that the results of primary and secondary amputations of the upper extremity were exactly the same; they both had a mortality of 65-75 per cent. Malgaigne has further proven that the results of amputations for organic bone and joint diseases are more favorable than those from trauma. . In the fortieth decade the immovable plaster bandage attracted the attention of surgeons and about the same time resections of joints began. Even in 1836 * 87 Pirogoff had not seen a single joint resection either in Berlin or in Paris. , . . This revolution of opinion is seen in most marked degree in the treatment of gunshot fractures of the femur. In these injuries even conservative surgeons were convinced of the necessity of amputation. The mortality, 90-95 per cent. of these amputations, however, operated to the benefit of conservative principles. In this war were found thirty cases of perfectly united frac- tures in the middle and upper third of the thigh while but very few cases of recovery after thigh amputations were observed. - But what neither he (Pirogoff) nor any other surgeon (?) could have anticipated was the so extraordinarily happy termination of a great number of cases of gunshot wound of the knce joint.” He counted forty such fortunate cases; $n Some cases, indeed, even motion was maintained in the penetrated joint and in two instances of recovery the ball was still in the bone. He ascribes these favorable results to the smallness of the chassepot projectile and the direc- tion of the wound, from before backwards. In the treatment of gunshot fractures of the thigh, the immovable bandage, the inclined plane or a particular bed and permanent extension played a great role. As to the immovable bandage, he says, it is often present only in appearance not at all, then, fulfilling its design. Only then does it meet its end when the limb is uniformly enveloped and when both joints at the extremities of the fractured bone are likewise enclosed. The method of its present application is as follows: A drainage tube is first introduced into the wound, this is covered with charpie when the whole limb from above down- wards is bandaged and covered with plaster. He next takes a large piece of gauze wire, such as the sieve makers use, cuts windows in it beats out its borders smooth, bends over the sharp ends and then envelops the limb with it over the plaster bandage. This is now in turn covered with plaster and this again finally with a bandage saturated in the same material. When the plaster sets, the substance covering the windows is cut out with a scalpel. Sometimes he uses the inner bark of the linden tree instead of the wire envelop whenever it is desirable to have large windows that a loosened bandage inside may be tightened or supported. His method of preparing the bandage for removal and reapplication is as follows: A flannel bandage is ac- curately applied to the injured limb. This bandage is uniformly smeared with a paste made of one pound of boiled starch and one and a half to two beer glassesſul of powdered gypsum. Several pasteboard splints plas- tered with this mixture on both sides are then adjusted * Neudorfer in his writings cites repeatedly cases of recovery after gunshot wounds of the knee joint, some of them with partial use of the injured joint. It is stated also in the appendix (p. 224) we may now cherish the hope as well founded, if it should become an axiom in military surgery, in cases of injury to the knee joint, to apply an immediate plaster bandage instead of resorting as hitherto to immediate amputa. tion. that the number of cases of recovery would be much greater; might be cited, indeed, as of daily occurrence instead of being regarded as rarities and fortunate exceptions to a rule. - - 66 [FEB. 3, 1872. TIE-ITED CT, IT INT I. C. ' upon the bandage and fastened with a linen binder which is again covered with the starch and gypsum paste. This application dries in six to eight hours. The whole bandage is then split through in its length and painted with cabinet-makers varnish. In its reap- plication a band is pasted along the divided edges and the whole is fastened to the limb with five or six ban- dages. e As to the inclined plane in the freatment of gunshot wound of the thigh, Pirogoff can not speak in its praise. The Simon's bed consists of several separate and separa- ble pieces of mattress for the pelvis and the two lower extremities with a means of extension at the lower end: yet here, too, is a gypsum bandage necessary. The patient seen on the bed by Pirogoff at Simon's had in consequence of absence of the bandage not only a short- ening, but also an angular deformity. The price of the bed is only 25 fl. [$10.] Nothing encouraging was visible in resections of the knee and hip. There were some 50 cases of recovery of gunshot wounds of the shoulder, elbow and ankle, with- out resection, a fact which is significant against the adoption of early resections. Of resections of the ankle-joint he saw some twenty, among them, one where both astragalus and calcis were removed. The constant warm bath which he designates as maceration of the injured joint was nowhere in use. Seventeen cases of ligation of large arteries were re- lated to him : results were very sorrowful. He thinks the reason of this bad result was the delay in operation, the patients being already reduced by loss of blood. The selection of the place for ligation was often enough unfavorable; in hemorrhage from the femoral artery, for instance, the ligature instead of being placed in the external iliac was applied to the middle and upper third of the thigh; in hemorrhage in the flexion of the elbow, the brachial instead of the axillary was chosen. Prof. Simon gives preference to digital compression within the wound over the dangerous ligature in the treatment of hemorrhages, and has had some success to show for its adoption. Pirgoff, does not believe, however, that this method will find general adoption, because these hemor- rhages only occur in gangrene or that bad form of Sup- puration which extends from the wound to the arteries in reduced, cachectic individuals, diseased condition o the vessel walls or in ligation near a departing branch. It is certain that a ligature at a place removed from the wound is better borne than when the pressure on the diseased vessel occurs in the wound itself. In a case where he would fear ligation, Pirogoff would give prefer- ence to galvano-puncture of the arterial trunk. Three times he saw the formation of varicose aneurisms after perfect healing of gunshot wounds. All three cases were situated in the inguinal region. Next is disºussed the amputation of limbs. He says, “This subject forms a chapter as melancholy in the mo'ern history of military 8wrgery as in the ancient—Death and again death—that has been the result earlier as well as later in the majority of cases of amputations in the past war.” What else became of the amputated, as so few were seen in the 70 lazareths visited? With this opportunity, he takes occasion to differ with Langenbeck who stated at the 74th anniversary of the Friedrich Wilhelm Institute, that field service could only be of use to the severely wounded when it began immediately after the battle and ceased not later than two days after it; all unavoidable amputations, there- fore, must be performed in the first 12–24 hours after the battle. The later and intermediary amputations give the most unfavorable mortality per cent. Against this view, Pirogoff maintains that conserva- tive treatment and late amputation are so indissolubly united that if the possibility of the first be granted, the probability of benefit from the last must be acknowl- edged. The former doctrine of Bouchet and Larrey was consistent; it demanded that amputations should be as quickly performed as possible, because it claimed that the preservation of limbs, was in general, more dan- gerous than their amputation, and taught that whoever did not amputate immediately after an injury ran the risk, in the attempt of saving more limbs, of losing more lives. So soon, however, as conservative surgery is con- sidered admissible into military service, so soon, to be consistent, must protest be entered against early ampu- tations. To defend conservative surgery and at the same time to advocate early amputations is to be incon- sistent at once. In considering the favorable course of early in comparison with the unfavorable course of later amputations, it must not be forgotten that it was only the upper extremity that furnished this favorable result. And here conservative treatment has been attended by the best results. At the lower extremity early, as well as late amputations show the same unfavorable results. Whoever here gives preference to late over early resec- tion must give the same preference to late over early amputations. In a word, the introduction of conserva- tive treatment in modern military surgery is of itself a protest against early amputation, which of course ad- mits of no preservation of the limbs. To the honor of modern surgery, he confesses, that on the whole but few amputations of the upper extremity were made. Of cases of exarticulation of the humerus he found only three or four alive, while after Sebastopol he saw some thirty cases recover. But one case of exarticula- tion of the elbow-joint he met—that was in Strasbourg, and was near recovery. Of amputations of the thigh he remarks that he found about twenty convalescents in Strasbourg—amputations at the lower and middle third—of amputations of the upper third he met with but one living instance. Usu- ally the circular incision was made, while he prefers the flap, and in support of his preference he notices the fact that the naked bone protruded in some ten of the cases here encountered. Amputation by Gritti's method was not performed. One case of recovery was observed after amputatio transcondyloidea. FEB, 3, 1872.] Tº H. H. CT, ITNTIC . 57 Of cases of exarticulation at the hip and knee, he found none living. Of amputations of the leg, also, but few were met, and of these, half showed the anterior angle of the tibia protruded from the ulcerated skin, simply because the flaps were tunited in the transverse instead of in the vertical direction. - Of his osteoplastic resections performed on six patients, five were in satisfactory condition. Concerning pyacmia he remarks that this occurred mostly after severe hemorrhages, especially when sec- ondary hemorrhages ensued upon amputations render- ing the repeated ligation of arteries necessary. Gangrene exhibited preferably the diphtheritic type, nowhere was the fungous or hemorrhagic form encountered. Hospital erysipelas showed itself contagious in a few lazareths where it was successfully treated with camphor. Acute purulent infiltrations were relatively seldom encountered in German hospitals. Tetanus occurred pericdically, and was treated in some cases with large doses of chlo- ral hydrate. Cyanotic cholera and scurvy did not anywhere pre- sent. As to the influence of syphilis on the treatment of wounds he could furnish nothing reliable. The fifth section of this interesting volume closes the book with suggestions for improvement of the Russian service, a subject only of interest, of course, to Russian readers. - —sº- e-º- scIENTIFIC NOTES. On NMultiple Metastatic Abscesses. }Y Von RECKLINGHAUSEN, (Würzburg.) Transactions Würzburg Physik-Med. Gesellschaft, As to the nature and origin of the multiple metas- tatic abscesses of the different infectious diseases encoun- tered in the organs supplied by both the pulmonary and systemic circulations, there have prevailed, hitherto, —in these cases where concomitant endocarditis was absent—the most varied opinions. The view of Vir- chow, that they were referable to capillary emboli has been the most plausible. V. Recklinghausen has succeeded in discovering in a series of infectious diseases, especially in pyaemia and puerperal fever, further in typhus and acute articular rheumatism, and finally in urinary infiltration and gan- greme of the lungs, the cause of the abscesses to be Żmiliary accumulations of minute organisms which are to be designated as microcci. These are identical with the forms described by Buhl, Oertel and Nassiloff in diph- theria, and Klebs in cystitis and pyonephritis, and are definitely determined, both by their appearance and nore especially by their great resistance to different chemical agents, even caustic alkaſies, to be animal bodies themselves or substances originating from the retrograde metamaphosis of animal bodies, In greatest frequency the author found these parasitic deposits in the kidneys, sometimes perfectly recent, without any manifestation of reaction about them, again, and more frequently, surrounded by a zone of tissue of hemorrhagic or purulent infiltration. Their accumulation in the kidney is not limited only to the bloodvessels of which the smallest veins contain the great- est quaſitity; the author found them also in the urinary tubules from which they had passed out with the urine, proof that they were contained, either intra vitam or post-mortem, in the bladder. The distension of these different canals is at times so great that they assume a varicose appearance and further on perforation is effected and escap' of masses of parasites. A further variety of parasite, in every respect different from the micrococcus, a variety consisting of an accumulation of a greenish color, the author discovered in a case of scarlatina; these parasites in this case were the constituents of small ab- scesses in the pyramids of the kidneys. The urine of the pâtient at the 6th day of the disease contained casts covered with the elements described. The frequency of this presence of these various para- sites in the kidneys and in the urine as well as their extension and multiplicity there, affords, in the authors opinion, a significant indication for the localisation of the problematic germs of infectious diseases in general. As emboli in the sense which Virchow attaches to them may these parasite metastases not be regarded. Their extra vascular position is opposed to this view— moreover the author has demonstrated micrococci within the alveolae of the lungs—and then what partic- ularly refutes this opinion is the fact that in a great number of closely studied cases concomitant endo- carditis was not present. The small accumulation en- countered but one time tipon the mitral valve may, in all probability, be regarded as metastatic in the same sense as abscesses occuring in other organs. TRANSFUSION OF BIOOD.—Three interesting cases of transfusion are recorded by Jürgensen (Centralblatt, No. 28). The first was a case of phosphorus-poisoning. The patient was reduced to the last extremity of weak- mess, and suffered from hemorrhage and jaundice, when, two months after the poisoning, about 580 cubic centi- meters of blood, taken from three healthy persons, were injected into the median vein. Nearly the same quan- tity of blood was at the same time taken from the radial artery. He began, to recover immediately, and in a month could leave his bed. A syphilitic eruption, from which the patient was suffering at the time, disappeared after the transfusion, and did not return till two months afterwards. In the second case, the patient was a young woman in a state of extreme debility from gastric ulcer, to which had succeeded peritonitis and pleurisy. The blood used in the operation had to be brought some distance to the patient's residence in small well-closed A 58 [FEB. 3, 1872. TIEEE E C T , T TNTT C. bottles. It had been previously defibrinated, and before use was warmed to the temperature of the body. At the first operation, 350 cubic centimeters were injected into a deep vein of the arm; and, ten days later, a Smaller quantity into the peripheral end of the radial artery ; while the same quantity was allowed to flow from the central extremity. This had no favorable result; and death subsequently ensued, after the evac- uation of the pleuritic fluid by paracentesis. The third case was that of a man poisoned by exposure to carbonic acid in the hold of a ship. Nearly a day after exposure to the gas, the patient was quite unconscious, and had irregular and interrupted respiration and paroxysmal muscular contractions, while the reflex irritability was quite lost. In this case, 400 cubic centimeters of blood were drawn from the median vein; and thereupon 375 cubic centimeters of defibrinated blood, taken immedi- ately before from three other persons, were injected into the same vessel. During the operation, the muscular spasms ceased; and after the patient had been for one hour in a warm bath, and subsequently had cold water poured over him, he was able to open his eyes and to drink. Three hours later, he answered questions; and on the next morning consciousness was perfectly restor- ed. Recovery was complicated by the formation of red maculae, which subsequently became gangrenous, on the skin. These were seen at the time of the operation, and presumably were due to stoppage of minute vessels. Jürgensen regards transfusion of blood as a most valu- able remedial measure in carbonic acid poisoning, and advises an early recourse to it.—Brit. Med. Jonrn., Dec. 23, '71. -—sº-º-º- MIEDICAL NEWS. American Medicine. From the London Med. Times and Gazette, Jan. 6, 72. We this week publish the first of a regular series of letters relating to the affairs and position of our Pro- fession in America, which we trust will alike prove useful to our subscribers here and gratifying to our American brethren. It has ever been our desire to foster progress in Medicine; and as there is no means more useful towards that end, or more honorable in every way, than giving credit to whom credit is due, we have deemed it advisable to secure the services of one of the most eminent men in the United States and in our Australian colonies respectively to keep our readers aw courant with what is doing in their several localities. It is at once our duty and our pleaure to watch the changes of Medical doctrine and the improvements in practice, as they are gradually evolved at home and abroad, as nothing has struck us so much of late as the marvelous strides American Medicine has made within a few short years. This was most forcibly brought home to us a short while ago, when we were asked to recommend a book as the best on each of a certain number of subjects. The list was not a long one, and yet about one-half of those we had it on our conscience to recommend were American. Now, if this is not say- ing much for ourselves, it is saying much for our American brethren. There has always been a number of Physicians and Surgeons in America quite on a par with the best in this country, but that number used to be very limited. Furthermore, the American school was marked by certain characters of its own—the cur- riculum was exceedingly short, only the merest smatterings of Medicine and Surgery could be picked up in the period; and, with the exception of those educated in the older schools and abroad, few of its representatives could boast of great scientific attain- ments. Nevertheless, the men so educated, had to encounter the exigencies of Professional life as best they might; and here the vigor of the national character came prominently into play—so that, though rough, the Medicine and Surgery of the States had an exceed- ingly practical character. We have used the past tense here; for all this, although within the memory of most men now in the Profession, is already a matter of history. American Medicine has fairly passed into the scientific stage of development. It is well for us to look this matter fairly in the face, and to ask how it has been that, in America, Medicine has made such mighty strides in such a short space of time. As to the reality of the advance there can, we think, be no question; it is evidenced in many ways, but in none more powerfully than in the modern Medical literature, periodical and permanent, of the United States. With the abandon- ment of their dirty calf-binding and bad paper, the Americans seem to have made other changes important in every respect; and though we have not yet done them the compliment of pirating, as it is called, their works on this side the Atlantic, it is not becanse they are not used, for they are daily to be seen in the hands of students and practitioners alike. We have heard it said that most of the American liter- ature, as it comes to us, is not new—only reproduced— and undoubtedly the criticism is in some sense true; but the existence of such a literature implies a demand for something more than the scanty facts of pocket text- books, and is itself an evidence of the advance of which we speak. But this eager desire for the higher kinds of knowl- edge is made still more clear, to those of us connected with certain London institutions, by the crowds of men from America who flock there and elsewhere, seeking to prepare themselves to take a position in their own country. We are constantly meeting Americans— young and old—who have left America for one or two years, which they are spending in traveling from school to school, here and on the Continent, picking up every* FEB. 8, 1872.] T EHI E3 CT, ITNTI c. 59 thing that is to be learnt, and storing it up for future use. Go to Vienna, and the great majority of the English speakers there to be encountered are Americans; So, too, though in a less degree, in Berlin, and So, too, it used to be in Paris. These men have left their homes in Search of knowledge, and we may be sure that, having acquired it, they will reproduce it with interest when the proper time arrives. These are the signs of American advance, and true indications of future American greatness. We ourselves here in London would do well to ponder these things, for there is, unhappily, a tendency among us, more especially manifested in certain schools, to a display of self-satisfaction fatal to progress. Un- fortunately, our system of Hospital education leads to fostel this; it is diligently instilled into the minds of our students that to learn their Profession aright it is unncessary to stir beyond the walls of their own Hos- pital. When ideas are bred in-and-in too long, the result is as disastrous as it is in animal life: a puerile conceit is apt to take the place of a masculine breadth of thought, and to beget its like in the minds of others. But our English students neither pass from Hospital to Hospital enough, nor do they go abroad. Of all the means available for expanding the mind, none are equal to travel; nor for producing catholicity in Medicine is there anything like foreign study. In this we fear even now the Americans are beating us. In the future we shall have to look to our laurels. HONORS TO THE PHYSICIANS OF THE PRINCE.--Dr. Gull and Dr. Löwe, who were associated with Sir Wm. Jenner in the treatment of the Prince of Wales, are to be honored, the first with a baronetcy, the latter with a knighthood. Dr. Gull is also to become one of the body physicians to the Prince. THE RITES OF Found ATION SACRIFICE.-There is current is Scotland the belief that the Picts, to whom local legend attributes buildings of prehistoric antiquity, bathed their foundation-stones with human blood; and legend even tells us that St. Columbia found it neces- Sary to bury St. Oram alive beneath the foundation of his monastery, in order to propitiate the spirits of the soil who demolished by night what was built during the day. So late as 1843, in Germany, when a new bridge Was built at Halle, a notion was abroad among the peo- ple that a child was wanted to be built into the founda- tion. These ideas of church, or wall, or bridge, want- ing human blood or an immured victim to make the foundation steadfast, are not only wide-spread in Europ- ean folk-lore, but chronicle or tradition asserts them as matter of historical fact in district after district. Thus, When the broken dam of the Negat had to be repaired in 1468, the peasants, on the advice to throw in a living nan, are said to have made a beggar drunk, and buried him there. Thuringian legend declares that, to make the Castle of Liebenstein fast and impregnable, a child was bought for hard money of its mother, and walled in. She was eating a cake while the masons were at work, the story goes, and it cried out: “Mother, I see thee still; ” then later, “Mother, I see thee a little still;” and, as they put in the last stone, “Mother, now I see thee no more l’” The wall of Copenhagen, legend says, sank as fast as it was built; so they took an inno- cent little girl, set her on a chair at a table with toys and eatables, and, as she played and ate, twelve master- masons closed a vault over her; then, with clanging music, the wall was raised, and stood firm ever after. Thus Italian legend tells of the bridge of Arta, that fell in and fell in till they walled in the master-builder's wife, and she spoke her dying curse that the bridge should tremble like a flower-stalk henceforth. The Slevonic chiefs founding Detinze, according to old heathen custom, sent out men to take the first boy they met and bury him in the foundation. Servian legend tells how three brothers combined to build the fortress of Stradra (Scutari); but year after year, the demon (vila) razed by night what the three hundred masons built by day. The fiend must be appeased by a human sacrifice—the first of the three wives who should come bringing food to the workmen. All three brothers swore to keep the dreadful secret from their wives; but the two eldest gave traitorous warning to theirs, and it was the youngest brother's wife who came unsuspecting, and they built her in. But she entreated that an opening should be left for her to suckle her baby through, and for a twelvemonth it was brought. To this day, Servian wives visit the tomb of the good mother, still marked by a stream of water which trickles, milky with lime, down the fortress-wall. Lastly, there is our own legend of Vortigern, who could not finish his tower till the foundation-stone was wetted with the blood of a child born of a mother without a father.—Journ. Psych. Med., Jan., 1872. CIRCUMCISION OF CORPSES.—The laws of Austria as is well known, forbid any compulsory execution of re- ligious enactments. Many Jewish parents have taken advantage of this to evade circumcision of their new born male children. Lately the discovery has been made that the corpses of those who died thus unconse- crated had been circumcised in the Jewish burying ground by some orthodox fanatics. An investigation has beea ordered by the Government with a view of the detection and punishment of the perpetrators.- Wien. Med. Presse, Dec. 31, ’71. A VALUABLE CARRIER PIGEON.—From the Elizabeth Daily Journal of New Jersey of Nov. 28 we have a marvellous story of a carrier pigeon, which we commend to the notice of Mr. Tegetmeier. It performed the journey from Sopus Farm, Warren Co., N.J., to Sandusky Ohio, a distance of 400 miles, in exactly an hour, and its condition on its arrival at the latter place is thus described:—I found the greatest excitement had followed the arrival of the pigeon. Mr. Smythe told me that at precisely two o'clock the 60 [FEB, 3, 1872. TIH. H. C.T.INI c. bird came like an arrow into his house. His movement was more like a blue streak than a well-defined bird. He seemed but little exhausted, although nearly all the feathers were off his body, except the small patch held on his back by the gutta-percha which fastened the note. A few miles more would have worn every feather from his wings, and then he would have to depend upon the momentum already acquired to carry him on his jour- ney, and to steer by a tailless rump, and perhaps be killed in attempting to alight.” No wonder the owner offers to match this pigeon “when he has grown a new suit of feathers” for 1,000 dollars against any carrier pigeon that has not done this distance in an equal time. —Nature, Jan. 4, '72. SMALL-Pox IN GERMANY.—The epidemic of small- pox increases everywhere in intensity. The mortality in Berlin alone reaches 9000; over one per cent. of the population. Compulsory vaccination has been ordered in Gotha. CEREMONIAL PURIFICATION.—The seclusion and lus- tration among North-American Indian tribes have been compared with those of the Levitical law, but the ro- semblance is not remarkably close, and belongs rather to a stage of civilization than to the ordinance of a particular nation. It is a good case of independent development in such customs, that the right of putting out the fires and kindling “new fire” on the woman's return is common to the Iroquois and Sioux in North America, and the Basutos in South Africa. These latter have a well-marked rite of lustration by sprink- ling, performed on girls at womanhood. The Hottentots considered mother and child unclean till they had been washed and smeared after the uncleanly native fashion. Lustrations with water were usual in West Africa. Tartar tribes in Mongolia used bathing, while in Siberia the custom of 1 aping over a fire answered the purpose of purification. The Mautras of the Malay Peninsula have made the bathing of the mother after childbirth into a ceremonial ordinance. It is so among the indigenes of India, where both in northern and southern districts the naming of the child comes into connection with the purification of the mother, both ceremonies being performed on the same day.—Journ. Psychol. Med., Jan., '72. - ——º-e-Gº- CLK NICAL Aſ ºf M C RAN ID. A. A NEW REMEDY FOR SMALL-POX.—A letter from Berlin, announces the use of a new remedy in the pres- ent epidemic of small-pox in Berlin by Dr. Zuelger, the Director of this department in the Charité. It is Xylol (Dimethylbenzol)—two atoms of water substituted by two atoms of methyl—of which 10–12 drops are admin- istered in gelatine capsule every two or three hours. of the epidemic renders its further trial easy.—Wien. Med. Presse, Dec. 31, ’71. CHLORAL IN GOUT.-Chloral must be an efficient remedy in this disease as Dr. Puglièse (Lyon Medicale, No. 21,) Says that he gave 30 grs. of it to a patient suffering horrible agony, “never closing an eye from Sept. 25th to Oct. 3rd, and ten minutes afterwards he fell asleep to awake in a condition of “béatitude indescrip- tible.” CHARCOAL IN GASTRIC AND ENTERIC DISORDERS.— Dr. Rémy highly commends the use of vegetable char- coal prepared from the poplar after the process of M. Belloc. He exalts its efficacy as “truly marvellous” in the treatment of gastralgia, gastro-enteralgia, dyspepsia, pyrosis, the greater number of nervous affections of the stomach and bowels, and constipation. It is a valuable adjunct in the tonic treatment of gastro-enteric affec- tions. In certain cases of dysentery it has also been found very useful, and in one such instance, reported by Dr. Farr, of London, its effects was very satisfactory in the form of enemata.-L' Union Medicale. CIILORIDE OF AMMONIUM IN HEPATITIS AND HEPAT- IC ABSCESS.—This remedy is highly lauded in all cases of hepatic derangement where mercury or other re- solvants are indicated, both in France and Germany. It is given in doses of one gramme [15 gr.] morning and evening.—Bull. Therap., Dec. 15, 71. - VoyſITING OF PREGNANCY TREATED BY ELECTRIC- ITY..—Dr. S. Iffla presented a memoire to the medical association of Victoria, (Australia) communicating the great value of electricity in cases of obstinate vomiting of pregnancy. In one remarkable case, defiant of all med- ication, where the patient was reduced to the last degree, prompt recovery followed the application of the constant current to the epigastric region. A recurrence of the same difficulty in the same case in a subsequent pregnancy as promptly yielded a second time to the same means.—Bull. Therap. Dec. 15, '71. —cº-O-ºs- I H [ON IFE NEWS. DURING the month of January 270 cases were treated at the College Dispensary. An abundance of material for physical diagnosis, eye and ear disease, specific dis- ease, etc., etc., is thus secured for the ensuing Spring Course. Quite a number of Reviews are crowded out this week for want of space. Wanted—Nos. 2 and 8 of THE CLINIC by Dr. G. C. Most excellent results are reported. The great extent | Conard, Peru, Ind. F. E. SUIR F. E. S. WAYNE F. E. suire & Co., WHOLESALE DBUGGISTS, INZL A-IN TJ E A C T U ER, TIN G- £HEMists AND f'HARMAceutists, CINGINNATI, OHIO. Have constantly on hand a full assortment of sxex,xecºcºo ox{U GS ANYO myx)&Yoxc)(xxes, cxxxeryxxCAX, Axºp AYKAYºus, TESTs, MEDICAL, GLAss waRE, &c, &c., And solicits the patronage of the trade and profession. We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, Made in accordince with the U. S. P. and other recognized authori- Ç8. FINIHE AND FE.A.R.H. CHEMICALs, Of the popular class of preparations known as IE T, IDX IIHR, S, We manufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them In the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. Bitter Wine of Iron, An excellent Chalybeate and tonic, Wine of Iron, &c. AGENTS FOR BULLOCK & CRENSHAW's Sugar-coated Pills and Granules. ) Price Lists of preparations and of Sugar-coated Pills sent by Mail "Pon application. The long standing and well and widely known repu- *tion of our house we offer as a guarantee for the reliability of our | P**Paration, and the quality of the goods sold by us generally. : tºº sº F= } JAMES FosſºR, JR., & Co. Instrument Makers and Practical Opticians, Beg leave to return thanks for the patronage extended to them through a long series of years (having" been established since 1836), and in the reorganizatiºn of their firm will endeavor to merit a continuation ºf the same, We wish it understood by the Professiºn and the Public generally |tº our invariable rule is, to make or import none but the best in . struments. 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Marsh, for the last tight years, tº the ex- clusion of all others, and have found it to give general satisfaction. effect- ing a radical cure, in the nuljority of cases, in a very few months. As a Truss for the radical cure of Ilernia, I think it lar preferable to any I have ever examined. LE \\ IS A. SAY RE, M. D. Surgeon, Bellevue Hospital. From Prof. Willard Parker to S. D. Townsend, M. D., Surgeon to the Massachusetts General IIospital. B EG leave to state for the benefit of all concerned. thmt I have known lºr. S. N. Marsh the last fifteen years. * * * I am in the constant habit of sending my patients to him for treattuent. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with a ti v of the risks to the patient that exist in many of the plans suggested aud at teulpted to be carried into execution. 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We import our own wood direct, and can sell at prices to compete with any and everybody. Also saw and keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. Office and Warerooms, 136 and 138 West Second Street, Veneer Mill, 507, 509, 511, 513 & 515 W. Sixth St., CINCINNATI, List of Pharmaceutical Preparations, MANUFACTURED BY Jonºv. Irrezºn & phozººn, PHILADELPHIA. —dº- ELIX PHOS. IRON, QUININE AND STRYCHNIA, ELIXIR OF GENTIAN FERRATED, , ELIXIR WALERIANATE OF AMMONIA, (Goddard’s Formula,) - ELIXIR VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, * Hron, with Phosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Iron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK, - ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, … COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER WINE OF IRON, Citrate of Iron and Peruvian Bark, * x FERRATED CORDIAL ELIXIR, ELIXIR, CALISAYA BARK, WINE AND BISMUTH, ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, * FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, * TASTEIESS COD LIVER OIL, TASTELESS CODLIVER OIL. FERRATED, BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and sherry wine, ELIXIRVALERIANATE OF STRYCHNIA, –––––– Q wiNE OF PEPSIN, SYRUP SUPERPHOSPHATE OF IRON. FEFSI. - * ELIXIR OF BISMUTH, COMP. FLUIDEXT. BUCHU AND PAREIRA BRAVA. st JFE” O’s IT ( > Fr LEs. Rectum, Waginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great eare, and of every variety of combination. Lists sent on application. SPONGE TENTS.—For the Urethra, of every size and style, made of finest quality of spongo. Wººf, º ſº. Zººs sº §º: ... AºA, ſº º A'A' ºr # 5. sºlº º sº sº E sº |Tºº ... " 3. º - t i §:2S. " º lºſſ!!!! º ...: ſ | || # L 2-5 tiºn - º * §ſº *Nº, N.' - * ſºft ... [i]||. S. ſº sº CINCINN ATI. E" A C TU L T Y - J A M E S G R A H. A. M., M. D., D E A N , Professor of the Theory and Practice of Medicine and Clinical Medicine. ROBERTS BARTHOLOW, M.D., & W. W. DAWSON, M.D., Professor of Materia Medica and Therapeutics. Professor of Principles and Practice of Surgery and Clinical Surgery W. H. GOBRECHT, M.D., C. D. PALMER, M.D., Professor of Anatomy. † - Professor of Medical and Surgical Diseases of Women. P. S. CONNER, M.D., º - T. A. REAMY, M.D., Professor of Surgical Anatomy. Professor of Obstetrics and Diseases of Children. – W. W. SEELY, M.D., JOHN L. CLEVELAND, M.D., Professor of Diseases of the Eye and Ear. Demonstrator of Anatomy. SAMUEL NICKLES, M.D., ...' CHARLES KEARNS, M. D., Professor of Physics and Medical Chemistry. Assistant to the Chair of Surgery. J. A. M. E. s r. W H ITT A R E R , * Professor of Physiology and Secretary of the Faculty. - s T. Louis BRowN, Prosector of Anatomy. ...' Janitor, College Building, Sixth St., bet. Vine and Race. Printed and Published by Norbus & M URBY, Medical College of Ohio Building, Cincinnati. THE CLINIC, PUBLISHED EVERY SATURDAY. * R. R. M. S.–$2.00 a Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editor: $ ~ 3 All Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer, Af --> Vol. 2. C IN C IN N A TI, F E B R U A R Y 10, 1872. No. 6. *— —r JAS. T. VVHITTAKER, M. D. * gº mºs Editor. No. 101 West Ninth Street, Cincinnati. Çgº A. Bºſ tº CO = JASSOCIE.A.T.E. Hºº). ITO.R.S. W. W. DAWSON, M. D. THAD. A. REAMY. M. D. ſº P. S. ConneR, iM. D. C. D. PALMER, M. D. F ashionable Hatter §s, W. W. SEELY, M. D. SAMUEL NICKLEs, M. D. CHAs. KEARNs, M. D. JNo. L. CLEvel,AND, M. D. IMPORTERS AND MANUFACTURERS OF RoBERTs BARTHollow, M. D. W. W. SEELY, M. D., - - - - - - TREASURER. #A}}{ES.” FºrS, No. 118 West Seventh Street, Cincinnati. 92 WEST FOTTERTIE-L ST. Opposite Post Office, C L J B R A T E S. *- 4 Copies to one address * * * * * * * * * * * * * * * * * * * * * * * * * * * = e e º a e º e º 'º $ 7.00 CINCININATI. 6 & 4 sº *~ 10,00 ' | *Special Inducements to Medical Men. I2 4 & 6 4. 18.00 | * ~ : 7 TV = alsº º, T. ºr sº C O N T E N T S. . . . . Boº Stºkºſan — Page. . ºbesic N E. Rs AND is oric INAL ARTICLEs º -ºblºn EKºº Agoraphobia, by John D. Jackson, M. D 6|| . E.NGR AVE R S O NWO ODI On the Treatment of Inflammations by Means of an Air-Exhaust- ºlº 2. Wºº U.5995 IH. Sãº-º-º: ing Apparatus, by J. Bradley, M. D. 62 : CINCINN: *TI; OHIO. TRANSI LATION Gastric Juice and Pepine Solutions in the Treatment of Syphilis J. TAFT, W. TAFT. and Cancer (from Schmidt’s Jahrbücher, Jan., 1872)................. 62 Editor Dental Register SCIENTIFIC NOTES Urea formed in the Liver—Electrophysiologica 64-67 J. & W W Q TAF T, MIE DI (CAEL NEWS The Oldest Existing Medical Work—Plague in Bombay—Heels vs. Brains—The Hop Pillow—Fertility of American Women............ 67 T) IET: INT T T S T S CORRESPONDENCE Letter from Berlin (from the Brit. Med. Journ. (Dec. 31, ’71).-An * Exegetic Document st 67-68 11 7 W EST FOU RT H STR E ET, REVIEWS The Principles and Practice of Surgery, by John Ashburst, Jr., CH N CI TN N_A_T}{ 9 O. M. D. Philadelphia, H. C. Lea, 1871—Pulmonary Consump- tion, by Jas. H. Bennet, M. D.—Traité des Maladies du Fond de L’Oeil, etc., by Wecker and Jaeger—An Ophthalmological 9) Encyclopedia—Consumption, its Pathology and Treatment, by Wade Minor Iogan, M. D. S. W. Butler, Phila, 1871.......... 68-70 A Monthly Journal, CLINICAI, NIEM [ORANIDA Electricity in the Treatment of Tumors.................................... 70-72 CONTAINING 48 PAGES, HOME NEWS * 72 The Spring Course of 1872........ .. Tº Devoted to the Interests of the Dental Profession, ROBT CLARKE & Co. William Autenrieth, PUBLISHERS, hillinºiſ, N0, 65 WEST FOURTH STREET, Call the attention of the Medical Profession to their Extensive Stock of &nglish, Āmerican and £venth J/AA/º/, Aº(262/.S. 'Paying particular attention to this branch of their business, they are enabled to execute all orders on the shortest notice, and at the most reasonable rates. Their facilities for the impor- tation of FOREIGN BOOKS, THE PROCEED- INGS OF SOCIETIES and HOSPITAL RE- PORTS are unsurpassed, and any orders en- trusted to their care will be filled promptly, and at the lowest rates. Subscriptions received for FOREIGN and AMERICAN PERIODICALS. All the New Publications received as soon as issued. Letters of Inquiry will receive our prompt and full attention. Catalogues furnished gratis on application. ROBERT CLARKE & Co., lºwhilºlº, mºtiºn PRINTERS AND BLANK BOOK MANUFACTURERS, 2eaders 22 Zaze,_Medicaë, Z/ºeoſoyacal, &chooč, azed./esce&azzeocas ZPoo/s, 65& West Fourth Street, CINCINNATI, O. * * |No. 71 wrest sIxTH sºrrºrder, BETWEEN WAINUT Añº WINE, CINCINNATI, OHIO, III in Immº III. Abdominal Supporters, Trusses, GLUB-F00T SHOES, SPINAL APPARATUS, ETC & Keeps constantly on hand a full variety of Metalic and Rubber Syringes, Storm.ach Pumps, Etc. stockings Foh waſticose veins. Special attention given to the fitting of Apparatus for Deformities. gº Agent for DR. L. A. BABCOCK'S Silver Uterine Supporter, -ALSO- DR. AHL's POROUS FELT SPLINTs, • --ALSO– D A Y’s ser, INTs *s, -AND- 6. S. We Elliott's Saddle=bags AHé iſſiſſilij º - *::::=ºſºft #Fººlſ: ºftº === i ºffl ºil- ===ºiſºft jºiº ". - #E; i # | | º *E. º ºf . . f .# i. º º | j. #|i. ##! |† º # * † := -:S, §§sºs §: 5. =#. - ſº !" -ºšilláſi | | Fº: B * … . . . a ſº- lºº º_º|||||| ~- Sº § | ES: º Ş. i: ſi. ºft Sºsº* § - ----- §§ § %233; ; šº iº G |º - The GOOD SAMARITAN HOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner of Sixth and Lock streets. It is handsomely furnished throughout, and is provided with all the necessary ap- pointments of a First-class Hospital. Porticoes, with commanding views, surround the whole house, and wide halls and abundant windows secure that full and free ventilation which is so essential to health and comfort. Service is furnished by the SISTERS OF CHARITY, Under the Superintendence of the well-known SISTER ANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. The regular Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each Professor presiding over his own especial department. Patients may, however, select from the regular profession of the city any physician of their choice. The GOOD SAMARITAN HOSPITAL presents extra inducements to Invalids throughout the State as a safe and quiet asylum in any case of protracted illness, or in cases, more particularly, requiring Surgical Operation, where some stay is necessary in after treatment. Rooms vary in price, according to the character of appointments necessary and service required, ranging, in general terms, between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand o service. - &" Address, SISTER ANTHON.Y., EIospital of the Good Samaritan, Corner of Siacth and Lock Sts., Cincipanati, Ohio. * * …” A : * * bºrº 2 *- - * : *% º E--- sº º NSJ Carriage NOS. 9 and 11 East Sixth Street, bet. Main & Sycamore. - I MAKE NOTHING BUT Jº ZAPS 7" CZ.Z.S.S. WºO /*A*. Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of - - LIGHT FAMILY CARRIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive variety of light elegant designs of different cost and finish. In vehicles especially adapted to - PHYSICEANs' USE. The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. t The superiority of my light gentlemen’s buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price lists furnished on application. References Wm. Wilson McGrew, & wo, ºr rasr rovara scºrer. PIKE'S OPERA, HOUSE BUILDING, In porter and Dealer Diamond and Gold Jewelry, Watches for Ladies and Gentlemen, Sterling Silver Tableware, Bronzes, Antique and Modern; Marble and Bronze Clocks, Marble Statuary, FAN cºr Coons, G E N E R A L L Y. DIVIDED MEDICINES, FREPAIRED BY The Divided Medicine Com’y, CINCINNATI, OHIO. The Company have the honor of bringing to the notice of the Profession, this NEW AND ExCEEDINGLY PRACTICAL METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. The Divided Medicines are prepared by FREDERICK KRAUs, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MORE. - The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every square will consequently contain accurately measured quantities. But not only SoLUBLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINES. : & * This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, } % #. sh. Ho, and even idoo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE TO SPOIL BY ANY LENGTH OF TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. - Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calis with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. For Samples, Price Lists, and Agencies, address The I) NºSº Yº º IBOX 2688, Or FRFDERICK KRAUS, Chemist and Druggist, Walnut Hills, Cincinnati, O. MR. FREDERICK KRAUs: t CINCINNATI, February 15, 1871. Dear Sir—The specimens of your “Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: - 8ULPH:MORPHII....................... % grain in each square. ARSEN: ACID.......................... 1-20 grain in each square. ** CH IN INI .......................1 * * * * $º CALOMEL 34 “ $ 4 $6 “. COPP108 ....................... ..}% .*. 4 & - RzsPeoTruſ.I.Y. YoUEs, E. S. Wayne, Analytic chemist ^ y T EEE EIH C T , T INTT C - 61 vol. 2..] s A T U R D A Y, F E B R U A R Y 10, 1872. [No. 6. O R. I.G IN A L A R T I C L E S. A G O R A P J H I O B H A • Eisophobia, Autophobia. BY JoHN D. JACKson, M. D. Danville, Ky. On p. 116 of THE CLINIC for Oct. 14, 1871, under the heading AGORAPHOBIA, is a short paragraph from the Archiv Psychiatrie, giving some account of a neuro- pathic affection encountered by Westphal, and to which he has applied that name. It says, the most essential symptom of it “is a most acute anxiety or fear, ex- perienced in open spaces, long passages, theatres, concert saloons, etc., with no other cerebral disturbance. This feeling of dread, is lessened if a wagon or an individual stand in close vicinity, as also in the neighborhood of a well known house.” '; Though I have no recollection of having elsewhere seen any account of this curious affection, yet inasmuch as I am myself cognizant of two cases, I doubt whether if attention of the profession were generally directed toward it, it would prove after all, to be so very rare. One of the sufferers is a medical friend residing in the country, and although he to-day still does quite a respectable practice, yet, as he informs me, he has not for years ventured out of sight of his house, without an attendant. Like in Westphal's cases, he is a man of intelligence, and has frequently brought to bear every argument which his reason could summon, and all the force of his will against it. Unlike Westphal’s patients, he has never been subject to epilepsy or to any symptoms standing in a close connection to epilepsy. Nor with him, is there any hereditary connection. I might say furthermore, that he is what the world would term “a Well balanced man,” and usually free from eccentrici- ties or oddways. In society, his temper is remarkably cheerful and good humored, and in estimating his char- acter, I should pronounce him rather a man of fortiter &n re, than timidity. For a long time, he was sensitive regarding his trouble, and tried to conceal it from the World, but of late years, has pretty much given up all hope of overcoming the difficulty, and looks upon it as an evil to be viewed and discussed, as any other malady of the flesh. - He has been kind enough at my request, to write out * brief description of his case, which I append. Before doing so, however, I would Suggest another name than that proposed by Westphal. By the word agoraphobia, I suppose he means to indicate a fear while out in pub- lic places, or highways [agora phobia], but if we analyse the cases, we find that this is not exactly so—since this dread only comes over the person when he is there alone. It seems to me that the term isolophobia, eisophobia or autophobia, would more correctly express it. “The affection which you have requested me to give some account of, I have suffered from for a number of years. To give you the opportunity of estimating the value of antecedents and sequences, I might tell you that in childhood, I had Hooping-Cough, attended by violent attacks of epistaxis, repeatedly bleeding until I was exhausted. On recovering from this, I had asthma, until I was fourteen years of age; at puberty I was about rid of asthma, but dyspepsia with its train of troubles and horrors set in, and was accompanied by obstinate constipation, and haemorrhoids, from which latter, I suffered repeated and exhausting hemorrhages. “About nine or ten years since, I commenced suffer- ing from palpitations, attended with a sense of great fear of death, and an intense desire all the while to have some person with me. Each attack gave me great un- easiness, fearing it would be followed by another. A thought of it filled me with dread, and I began to avoid traveling about by myself, but on account of my re- covering so rapidly from the sensations, I would take heart, and kept my troubles to myself, and for a year perhaps I did not mention them to a soul—not even my wife—for all the while I was impressed as much as any one could be, with their puerile character, and feared on speaking of them, that I would be laughed at, or not believed. The spells grew more frequent during the next two or three years, though for two years, I never had one while in company with a single human being, even a helpless child; but in the third year, when in company with a single individual, I occa- sionally suffered it in an unfrequented place, and more especially when at a considerable distance from a house, but never when in close company with two or more persons. This grew upon me, until I was afraid to go a hun- dred yards by myself, even out in my own premises. Any violent physical exertion at this time produced suffering. Engaged at the time in the practice of med- icine and farming, of course my business had to suffer, and I grew melancholy, feeling that all my prospects in life were blighted. I however tried manfully to brave off the spells, though at each time I permitted myself to be alone, I suffered terrible agony from the sense of impending death, which was always accompanied by palpitations and rigors sometimes culminating in actual shakings, and occasionally accompanied with severe neuralgic pain in my back, and side or shoulders, followed by heat and thirst. My sufferings were great- est between 1866 and 1869, during wnich time I under- went two operations for haemorrhoids. Since then, 62 [FEB. 10, 1872. T IEEE THE C T , T IN. T. C. being cured of my hamorrhoidal troubles, and never venturing to go out by myself, I have grown somewhat better. “I have faithfully endeavored to break up this trouble in every conceivable way, but reasoning and medication have been in vain. As I have before inti- mated, I have again and again voluntarily been alone, and have tried to abstract my mind by firing shot after shot from my revolver, riding my horse at full speed, hallooing, whistling, counting, reading, and heaven only knows what all, but every expedient has been in vain. For six or eight years, I may say that I have never traveled a quarter of a mile alone, and as silly as it may sound to other ears, I but speak the plain truth, when I tell you that to-day, the wealth of all the Indies could not tempt me to do so.” ——-º-O-º- The Treatment of Inflammations by Means of Air Exhausting Apparatus. BY J. BRADLEY, M. D. St, Marys, Ohio, Dr. Arnott of London, I believe, has the credit of being the first to apply a partial vacuum to the lower extremities as a substitute for blood-letting; and from the reports I have seen with entire success. Notwith- standing the favorable reports given, it has, it seems, attracted but little attention in the old world, and about none at all in this country. Being impressed with the efficiency of inducing a vac- uum in the lower extremities for the cure of certain diseases, I had a pair of exhausters made after my own notion, vacuum boots I may style them, about three years ago, which I have been using since in every case that would admit of such treatment, and with really wonderful results. Profound congestion may thus be induced in the lower extremities to extent, indeed, of approaching syncope. This for the cure of certain in- flammations, is surely more potent for good than blood- letter can be ; for not only is the blood detracted from the inflamed parts, but it carries with it the nerve force that induced the inflammation. Physiologically considered it could not otherwise than have this effect. This is not the case in blood-letting. Many a patient, years ago, I have bled in pneumonia, and have observed that after the bleeding the congestion was the same. But in using my exhausters I have never been disap- pointed; the effect is certain for good if they are only used early in the disease. In all cases of congestive headaches that occur in fevers, or otherwise, I have succeeded in checking the pain in from five to twenty minutes, and this, as yet, without a single failure. I have had one case of epistaxis, and one of hemoptysis; both these were checked at once without the use of other means. For the cure of inflam- mations, I set my patient well up in bed, then apply my exhausters and bring him to the condition of an approaching syncope; if this be not brought about in ten or fifteen minutes, I begin to give small doses of antim. tart. or tr. lobelia, which soon induces the desired effect. In this condition now, I hold my patient an hour or more, to produce a lasting impression. I place him then in dorsal decubitus, give him a Dover's powder and apply a hot brick to the feet; if the inflammation be in the first stage, the treatment is ended—my patient is well. From the trials I have made in pneumonia I think I have lost my last patient from that disease; if I have been called during the congestive stage. I will give cases hereafter. —e-e—e-– Gastric Juice and Pepsime SoHutions in Cancer and Syphilis. BY DR. AUG, STöHR, Private Docent (Würzburg). Lussana, in particular, has recently recommended the gastric juice of the dog removed by fistula for the de- struction of malignant neoplasms; after him, the Italian, physicians made numerous experiments with the same agent. Stöhr's experiments began in winter (1869) while he was assistant at the medical clinic at Würz- burg. These he continued afterwards in private prac- tice and in his subsequent position of Ordinarius in the syphilitic department of the Würzburg military hospital where abundant material was present. It seemed of greatest importance to study the action of gastric juice on inoculable secretions. The author selected as the most suitable subject the inoculable chancre as this could be produced to any extent by inoculation rendering all kinds of experimentation possible. . At first was employed the juice taken from the stom- ach directly by fistula. The fistula was made in the usual manner. Escape of the contents of the stomach was prevented by the insertion of a canula or by simple cover of the orifice. During the first four or five weeks the opening remained sufficiently large, then exuber- ant granulations interfered to partially close the wound, so that many difficulties in obtaining the juice were experienced. It was furnished purest when, after the animals had hungered for a short time, small stones or bone fragments were introduced. The chyme was then strained through a linen and flannel filter. A tolerably clear fluid of acid reaction and amber color was thus obtained. The quantity secured, in several experiments, amounted, in a dog of average size, to 40–160 grim. only. The juice was easier obtained from a dog that had been killed as Schiff has stated. On several occasions, also, Wittich's method of obtaining the juice in glycerine was adopted. The juice of birds (owls and crows) which FEB. 10, 1872.] T ET H. C.T.I.N.I.C. 63 possesses the greatest digestive and antiseptic action was obtained by the old method of Spallanzani, viz., by the introduction of sponges into the oesophagus. To preserve the juice prepared artificially, variable quantities of hydrochloric acid and a small amount of chloride of so- dium were added; the fluid was then placed in well stoppered bottles where it would be preserved for sev- eral weeks without decomposition. The application was made either with a pencil by means of which the juice was painted over the surface 15–20 times a day or small pieces of cotton were satu- rated in the solution and kept upon the surface; in this latter case a larger layer of wadding soaked in a very dilute Solution of hydrochloric acid was applied over the cotton. The dressing must be kept constantly moist, since the transformation of albumen into peptones can only occur in the presence of an abundance of water. The following was the method of treatment of the chancres induced by inoculation. The application of the juice was commenced assoon as the ulcer has reached the size of a silver dime (8th–10th day). In almost all cases it was perfectly painless, a few patients stating that they experienced a slight itching or slight burning sen- sation at the margin of the ulcer shortly after the first application. An examination after three or four hours showed upon the surface a layer of grayish-white semi- transparent substance of * gºlaºu, aspect. In rarer cases this could be removed as a ‘continuous membrane; it adhered with moderate firmness so that it could be removed but with difficulty by a stream of water let fall beneath it. This was seen under the microscope to consist of corium elements and different forms of cells. As the application was continued this gelatinous layer became thicker though a purulent fringe was still dem- onstrable at the borders; after 24–36 hours, the borders Were somewhat contracted presenting less of the appear- ance of being punched out. If now the application of the juice was discontinued and the ulcer left without dressing, the gelatinous layer gradually dried, contracted concentrically and the surface presented a vaulted gray- ish-white crust of horny firmness, difficult to detach. Beneath this often was a layer of thick creamy pus. If this incrustation were not removed it remained fixed 5–11 days. Cicatrization then commenced about its edges and if it were now detached by force—which Would cause often hemorrhage—the ulcer beneath it Was found much smaller and with a good granulating surface. Perfect coating of the surface would then fol- low in a very short time under simple water dressings. In most cases, however, the author detached this layer several times from the bottom of the ulcer and applied *nd reapplied gastric juice until satisfied that no inocul- able material was left behind. The tendency of these ulcers, then, towards cicatrisation was particularly marked and followed usually between the fourth and *Venth day. In order to assure himself that this favor. able effect was not partly or totally due to the hydro- chloric acid always present in the juice employed, the author made numerous experiments which yielded al- ways negative results. The digestive fluid acts upon the ordinary chancre in the same way as upon that pro- duced by inoculation. In forty cases the mean duration of treatment was a fraction over nine days, the shortest five, the longest seventeen days. The inoculability of the secretion of the ulcer is totally lost after long con- tinued application of the gastric juice. In repeated ex- periments it was proven that inoculations with neither the translucent layer mentioned nor with the pus of the granulating surface after detachment of the crust could produce any reaction. To establish these results most conclusively he experimented in the following manner: in one series of cases he inoculated with a mixture of the pus of a freshly opened bubo with ten times its vol- ume of a dilute solution of hydrochloric acid, in another series with a mixture of the same pus with ten times its volume of the gastric juice of the dog. In the first series (six in number) but one inoculation failed, in the Second series no single inoculation succeeded, showed even not the least reaction. The author is of opinion that the gastric juice has, in a certain sense, the full action of a caustic. The inocul- able material of the secretion of the ulcer is totally destroyed, as also, of course, the inoculability of the secretion. This destruction is effected without pain, gradually, interstitially, penetrating to and macerating the ultimate histological elements of the tissue. To what depth the tissue must be “digested” to transform an infectious ulcer into a simple loss of substance, only experience with individual cases can teach. So soon as the conviction is reached that this transformation has been affected, so soon may the treatment with the juice be discontinued. Phagedemic chancres treated in this way are soon covered with luxuriant granulations. Condylomata and syphilitic neoplasms call for this treatment only when the surface is ulcerated. This transformation of the tissues into peptone re- quires a large amount of gastric juice and on this account the use of the juice for the destruction of large carcinomata and similar tumors has but little promise of success. It is probable, however, that after the ex- tirpation of such tumors the prolonged treatment of the base by applications of the juice wonld prevent their recurrenbe. Tissues which are highly vascular con- tra-indieate injections of gastric juice. Diphtheritic membrängs are easily dissolved or rather digested with large quantities of gastric juice. Whether this result may be obtained by simply peneiling the surface of the fauces is doubtful. The author has only tried the appli- cation to one light case of diphtheritic angina in Scarla- tina. He used the artificial juice and brought it to the surface with an atomizer. The individual “plaques” rapidly disappeared. It is probable that the gastric juice in this case attacks the low vegetable organisms which are known to exuberate so luxuriously in diph- theritic membranes. * 64 [FEB. 10, 1872. TIH. H. C.I.IISTI c. The most active of the different kinds of gastric juice was that obtained from fistulae or from the stomachs of dead dogs. The varieties of pepsine sold in the stores are only of value when not mixed with starch. The author usually employed a mixture of pepsine, one grn. [15 gr.] dissolved in 100–150 grim. distilled water to which were added 5–10 drops solution hydrochloric acid and 0.5 grm. common salt. Such mixtures are certainly inferior in the energy and rapidity of their caustic and disinfecting action to the natural juice, but they com- pensate for these deficiencies in the facility of their obtainment. --—sº- e <>--— — — — SCIENTIFFIC NOTES. UREA FORMED IN THE LIVER,-Next to the forma- tion of the urea physiologists are most interested in the place of its formation. Is the urea first made in the blood, and have the kidneys only to eliminate it? Or are the kidneys the place where it takes its origin 7 To solve this contested question N. Gréhant repeated in C. Bernard's laboratory the following decisive experi- ments. He extirpated both kidneys of a dog, and found, after this operation, that the blood contained more urea than before. The same results followed the placing of ligatures ºn the ureters. Both experiments proved the accumulation of urea in the blood. If the blood of the renal vein and artery of a perfectly healthy kidney be examined, it will be found that the venous blood contains less urea than the arterial, which shows us that some urea is lost during the passage of the blood through the kidneys. If the two ureters are tied so that no urea can be eliminated, the blood in the veins and arteries contains the same per-centage of urea. This is an indisputable proof that the urea is not formed in the kidneys, otherwise the venous blood would contain more urea than the arterial. The great mass of urea in the blood after the extirpation of the kidneys proves the same, for if this were not true the production of urea would cease after the kidneys have been extirpated. To determine the quantity of urea Gréhant used Millon's fluid. - . . - - Induced by the observations of Gréhent, Cyon at- tempted to prove that urea is produced in the liver. To this end blood was taken from the carotid of a dog which had not been narcotized, quickly defibrinized, and a part of it placed in an apparatus by means of which, it was to be forced through the liver. These, tubes were introduced respectively into the vena cava inferior, arteria hepatica, and vena porta, then the liver cut out of the body and placed in a vessel heated to the temperature of the blood. The first tube was connected with an aspirator, the second and third with the above- mentioned apparatus, in which the blood was contained. The circulation of the blood through the liver could be kept up by means of a connecting tube, which returned the blood on its arrival in the aspirator into the first showing that, in this Bº vessel, from which it could be again forced through the liver. After the blood had been several times passed through the liver it showed a greater per-centage of urea than a like quantity of the active blood of the same animal. Cyon draws, therefore, the conclusion that the liver is the place of formation of the urea. He promises, at the same time, to follow these short communications with a more elaborate article. (Hr. E. Cyon, “Ueber Harnstoffbildung in der Leber,” “Centralblat für die medicinischen Wissenschaften,’ 1870, No. 37.) p. 580.- Brit. For. Med. Chir. Rev., Jan., 1872. - – sº-º-º- E L E G T R o P HY s I o Lo G 10 A. Being an Attempt to show how Electricity may do much of what is commonly believed to be the special work of a vital Principle. BY C. B. RADCLIFFE. [From Nature, Jan. 4, 1872.] On a white marble slab let into the front of a house in the Strada Felicº at Bologna is an inscription house, then this temporary dwell- ing place, at the beginning of September 1786, Galvani discovered animal electricity in the dead frog, and hail- ing this event as the well-spring of wonders for all-ages (Luigi Galvani in questa casa di Sua temporaria dimora al primi di Septembre dell' anno 1786, scoperse dalle morte rane La Ellettricita Animale—Fonte di maraviglie a tutti secoli). Animal electricity, well spring of wonders for all ages! Yes, said I, as I copied these words a few weeks ago, and as I went into the house repeating them to myself. Yes, still said I, after seeing what was to be seen within the house. Within the house, indeed, there was much to excite the imagi- nation and to make me more ready to accept these words as the sober utterance of simple truth. Still the same were the common stairs leading from the open, outer door to the landing on the first floor, with its two main doors, one on each side, each one opening to a distinct set of apartments, in one of which had lived the discoverer of animal electricity; and the only change of moment was one which served to call back more vividly the memorablé past—a portrait in lithograph of Galvani himself hanging upon the wall facing the stair-head. Still the same was a third and smaller door, at which the portrait seemed to be looking, and beyond which were the stairs leading to the belvedere on the roof so common in Italian houses here- abouts. Still the same were these, stairs, the lower flights of even bricks, the upper of ricketty woodwork, unmended, scarcely swept, since the time when Galvani went up and down them afire with the discovery made FEB. 10, 1872.] T EEE CT, IISTI c. 65 in the belvedere to which they led. Still the same was the belvedere itself—the same walls, blank on one side, pierced on the three others with arched openings, two at each end, three at the front, each opening being built up breast-high so as to form the parapet—the same roof overhead with its bare rafters and tiles—and, run- ning across, each opening a little below its arched top and parallel with the parapet, the very same iron bar upon which the frogs' limbs had been suspended by cop- per hooks in the experiment to which the inscription on the slab outside the house refers. So little change was there, indeed, that, forgetting the present altogether, I could only think of this experiment in which the ex- istence of animal electricity was divined, and of those myriad other experiments to which it had led, and by which in the end the truth had been made manifest. So absorbed was I in these thoughts that I even forgot to look through the open arches of the belvedere at the blue Italian sky and other beauties of the prospect. And when at length I came down, I was more than ever in the mind to assent unhesitatingly to the words, “la elletricita animale, fonte di maraviglie a tutti secoli” —more than ever convinced that animal electricity would prove to be the key by which to unlock not a few of the secrets which are supposed to be exclusively in the keeping of life—more than ever resolved still to go on seeking for truth in the path along which I was urged to go by this conviction. Nor was I long at a loss how to begin to carry out this resolntion. I wanted to reiterate briefly and more clearly some of the things which I had said before respecting animal electricity, and the way in which this force may do a work ascribed to life in muscular action and nervous action; and at the same time to make use of certain new facts which were not a little calculated to confirm former conclusions. I wanted to show that the same workings of animal electricity may be detected in the condition called tone, and even in growth, and that these processes, no less than muscular action and nervous action, may have to be looked upon as electrical rather than as vital manifestations. A natural way of carrying out the resolution I had formed was, indeed, to do the work ready for me; and therefore the task I have now set myself is to do this work, begin- ning with an attempt to set forth a new theory of animal electricity, and then proceeding to say some- thing in turn on the way in which this theory sheds light upon muscular action, nervous action, the mainten- ance of the state called tone, and the process of growth in cells and certain fibres—something calculated to show that in each of these cases animal electricity may have to do much of what is commonly believed to be the work of a vital principle. 1. On a theory of animal electricity which seems to arise *aturally out of the facts. A Current, to which the name of muscle-current is §lven, may easily be detected in living muscle. It may be detected by applying the electrodes of the galvanom- eter, the one to the surface made up of the sides of the fibres, the other to that made up of either one of the two ends of the fibres, and also, though much less clearly, by examining either of these two surfaces singly, provided only the two points to which the electrodes are applied are at unequal distances from the central point of the surface. It may not be detected, if, instead of applying them in this manner, the electrodes are applied so as to connect either the two surfaces made up of the ends of the fibres, or two points equidistant from the central point of the surface made up of the sides, or of that formed by either one of the ends of these fibres. A current may or may not be detected under such cir- cumstances, and when it is detected its direction is such as to show that the surface made up of the sides of the fibre is positive in relation to that made up of either one of the two ends, and that the former surface is more positive and the latter more negative as the distance in- creases from the line of junction between these two sur- faces. In this way the galvanometer makes known the existence of points of similar and dissimilar electric tension in living muscle; and the only inference from the facts would seem to be that there is a curreat when the electrodes are applied so as to bring together points of dissimilar tension, but not othelwise. The facts are not to be questioned. The inferences arising from them can scarcely be mistaken. This current is to be detected in living muscle, but not in muscle which has passed into the state of rigor mortis. As muscle loses its “irritability,” indeed, it ceases to act upon the galvanometer, and no trace of the current is to be met with after the establishment of rigor mortis. As a rule, too, nothing is to be noticed except a gradual failure of current ; bnt now and then (though not in the frog) there may be a reversal in di- rection in the last moments preceding this final disap- pearance. * * * * * These, then, are the facts which may be looked upon as fundamental. There are the facts brought to light by Du Bois-Reymond through the instrumentality of the galvanometer—the muscle-current, present in living muscle during the state of rest, suddenly disappearing wben the state of rest changes for that of action, grad- ually disappearing as muscle loses its “irritably,” and absent altogether in rigor mortis; there are the facts which I myself have been able to make out for the first time by means of the wonderfully sensitive new quadrant electrometer of Sir William Thompson—the two op- posite charges of electricity, one positive, the other neg- ative, present in living-muscle during the state of rest, disappearing suddenly when this state changes for that of action, gradually disappearing before, and altogether absent in rigor mortis. And this is all that need be said upon this subject at present. And as in muscular so in nerve tissue, there is the current, in this case called the nerve-current, and there are the two opposite charges, positive and negative, this 66 [FEB. 10, 1872. TIEEI IEH C T , T: INT I. C. current and these charges being present during life, dis- appearing suddenly when the state of rest changes for that of action, disappearing gradually pari passw with the “irritability,” and absent altogether at the time when rigor mortis seized upon the muscles; and in truth every particular in the electrical history of the muscle is repeated with strict exactness in the electrical history of the nerve. In these two tissues, muscle and nerve, there is no difficulty in arriving at a knowledge of these facts; in other tissues, indeed, all that can be said is that faint indications of electricity are to be detected during life only, and that in Some of the fibrous structures there are differences between the surface made up of the sides of the fibres and that made up by either one of the two ends, which correspond to those met with in muscle and nerve. - These then being the fundamental points in the his- tory of animal electricity, the question is as to their meaning. To what theory do they point? In order to account for this muscle-current and nerve- current, Dr Du Bois-Reymond supposes that the muscle- fibre and nerve-fibre (the same law applies absolutely to both) are made up of what he calls peripolar molecules —of molecules, that is to say, which are (with the ex- ception of certain moments in which these electric rela- tions may be revresed) negative at the two poles and positive in the equatorial belt between those poles. He supposes that the sides of the fibres are positive because the positive equatorial belts are turned in this direction, and that the two ends are negative because the negative poles of the molecules face downwards to the ends. He supposed also that the muscle-current and nerve-current are merely the out-flowings of infinitely stronger currents ever circulating, closed around the peripolar molecules of the muscle and nerve respectively. And this view no doubt has much to recommend it. But another view may be taken of this matter—a view according to which this electrical condition of living muscle and nerve during rest is, not current, but static; and this view is that which recommends itself to my mind as in every way more simple, more compre- hensive, and more to the point practically. In taking this view the great resistance of the animal tissues to electrical conduction serves as the starting point. I assume that parts of these tissues may be bad enough conductors to allow them to act as dielectrics. I assume that the parts which are thus capable of act- ing as dielectrics are the sheaths of the fibres in muscle and nerve, or the cell-membrane of the contractile cells of those fibres in muscle which have no proper sheath. I assume that a charge, usually the negative, may originate in the molecular reactions of the contents of the sheath or cell-membrane, and that this charge, act- ing upon the inner surface of the sheath or cell-mem- brane, may induce the opposite charge upon the outer surface of the sheath or cell-membrane, and that in this way the sheath or cell-membrane during rest is virtually a charged Leyden-jar. I assume this charge is dis- charged when the state of rest changes for that of action. I assume that the surface made up of the sides of the fibres in muscle and nerve is positive because positive electricity has been induced upon this surface, and that the surface made up of either cut-end of the fibre is negative, because the negative electricity, developed upon the inner surface of the sheath or cell-membrane, is conducted to these ends by the contents of the sheath or cell. - All that I assume, indeed, may be readily illustrated upon a small cylinder of wood, left bare at its two ends, and having its sides covered with a coating which may be charged as a Leyden-jar is charged—a threefold coating, formed of an inner and outer layer of tinfoil, with an intermediate layer of gutta-perchasheeting, the latter layer projecting a little towards the two ends of the cylinder, so as to secure the necessary insulation of the inner and outer metallic surfaces; for by charging the inner layer of foil with negative electricity, this cylinder, which may be regarded as a model of muscular fibre, is found to be, not only positive at the sides and negative at the two ends, but more positive at the sides and more negative at each end as the distance increases from the line of junction between the sides and ends. With this model thus charged, indeed, it is easy to im- itate all the phenomena of the nerve-current and muscle- current, provided the electrodes of the galvanometer be applied in a suitable manner, and the charge be kept up. With this model thus charged, it is also easy to imitate all the tensional phenomena of nerve and muscle which are made known by the electrometer. And thus the nerve-current and muscle-current, instead of being out- flowings of infinitely stronger currents ever circulating around peripolar molecules, may be secondary phenom- ena only, the accidental result of dissimilar electric tension upon the surface of the fibres of muscle and nerve being brought into relation by means of the galvanometer or the electro-meter, as the case may be. X % + 3 + These, then, being the facts, it was evidently useless to go on searching for any numbers which could express anything like a common mean of resistance. It was evident, indeed, that the Soft tissues, one and all, apart from moisture, were to be looked upon as insulators, rather than as conductors. Nay, it was possible that they might be insulators rather than conductors even in the fresh state; for it is quite supposable that in this fresh state the walls of the fibres and cells forming these tissues may be virtually dry, with moisture on each side, not with moisture percolating from side to side, and that the degree of resistance presented by these tissues, when fresh, is not that which would be encoun- tered if the current passed across these walls, but that which is encountered by the current in passing along their outer moistened surface. It is quite supposable. that the measuring current may not pass across the walls of the cells and fibres at all, but may glide over and FEB, 10, 1872.] TIH. H. cI, IISTI c. 67 between them only. All this is supposable; and there- fore, the facts being as they are, I am, as I conceive, at liberty to assume that the walls of fibres and cells are sufficiently non-conducting to justify me in adopting the theory which I have ventured to propose—a theory, according to which, the electrical condition of muscle and nerve during rest is, not current, but static—the sheath of the fibre, or membrane, taking its place, being always charged as a Leyden-jar is charged, except during the time of action when there is a discharge of this charge—a theory which, to say the least, has a less visionary foundation than that which rests on peripolar molecules seeing that it rests upon structural facts which cannot be called in question—a theory also which, as will be seen in due time, has this in its favor, that it will simplify not a little several important problems in physiology. - - —sº-º-º- MIE OLEGAL NEWS. THE OLDEST MEDICAL WORK IN EXISTENCE.-An Egyptian papyrus, written in the days of Cheops, the monarch of the Fourth Dynasty, has recently been pre- sented to the British Museum by the Royal Institution. It is 7 feet 6inches long by 7 inches wide. Its contents are a series of recipes or modes of cure for different maladies, unaccompanied by any diagnosis or account of the dis- ease itself. Among the drugs mentioned are wax, fat, and incense. One remedy is for hemorhage from the head and other parts of the body, shavings or twigs of acacia, grains of a substance called kašpr, to be burnt; also milk, branches of olive, the hair of a cat, and honey. Many of the recipes date from an early period, as that of Amenophis III. of the eighteenth century.—Com- pendium of Medical Science. PLAGUE IN BOMBAY.—In the native State of Rolapore in the Bombay Presidency sheep suffered from a strange form of animal plague. This consists of a swarm of unusually voracious leeches. Besides this the Wolves were out, carrying off children, invalids, and the aged in the exposed villages. HEELs vs. BRAINS.–To show how very tenacious ladies are on this point, last year I was sent for to see a young lady in one of our London hotels. She wished to consult me about her foot. On Seeing it, I thought its state depended on her boots, and I asked to see them, The boots were brought in by the lady's maid, but the only thing I could observe about them was an im- mensely high heel. I said, ‘It is the high heel of your boots that causes the mischief, and unless you diminish this I can do nothing for you.” She became quite angry, and said she could not alter them: ‘I cannot do it, and I will not.” Suddenly she toned down, and said, ‘Pray, sir, what would people say if they saw me walking about the Park without high heels?' I said, ‘It is sim- ply heels versus brains. If you have brains, you will cut off the heels; if you have no brains, you will con- tinue to wear them.” She fortunately had brains, cut off the heels, and her foot got quite well.—Hewett— Phil. Times, Feb. 1772. THE HOP PILLow.—During the illness of the Prince of Wales, when all other remedies failed to produce a Soporific effect, the old-fashioned hop pillow was placed under his head and quiet sleep followed. THE AMERICAN MOTHER GROWING LESS PROLIFIC. —Dr. Toner of Washington, D. C., the statistician, in his diagram shows that what is held up as the peculiar shame of Massachusetts is equally true of all her sister States. It is shown that only one-half as many children are now born to each thousand women as in 1800, and that there has been a regular decrease from one decade of years to another. —-º-º-º- CORRESPONDENCE. How Professors are Appointed in Germany. It cannot but seem surprising that the appointment of a man so widely and favorably known as Frerichs is should have called forth So outspoken an opposition; and one can only find in this incident another illustra- tion of the maxim that, in appointments such as this, and in the election of university professors, no other consideration but that of efficiency is to have any weight. Another illustration of the same thing is to be found in the circumstance connected with the election or a suc- cessor to Oppolzer at Vienna, where a great clinical professorship has been standing vacant; and, though this delay points to a conflict of interest, it also betokens clearly enough a high sense of responsibility impressed upon those who have the patronage. From the oppo- sition that they have excited, both the Frerichs affair and the appointment at Vienna may be regarded as exceptions of the kind that prove the rule; and they at the same time prove clearly enough that, if in Germany the best man is usually chosen for the post, the cause of this is not, as has been alleged, that the patronage is exercised by a Minister of State. It is hardly an exag- eration to say that the man who is best entitled to this or that vacant professorship in science or in medicine can be pointed to in much the same way as at Cam- bridge one may hear who is to be the first wrangler on the next occasion. In both cases, the antecedents of the individual—the work that he has done—are freely can- vassed; and they constitute the reliable data to judge by. The whole system of study at a German University is calculated to bring the able and zealous workers in any department into the clearest prominence. A stu- dent, as he advances in his studies, develops a talent for this or that particular branch, which he is at liberty to follow out unrestricted. He enters a laboratory, and 68 [FEB. 10, 1872. TIEEE THE CIT, ITNT I. C. there undergoes a course of training ; and, when he has passed his professional examination, if he have a mind, he is encouraged to resume his work in the laboratory; and in course of time he completes some original re- search, as in physiology or pathology. Then, if he have shown himself a capable worker, he gets the next vacant assistantship; and if, as an assistant, he do not in the course of a year or two make some considerable contri- butions to the researches in his department, he is looked upon as falling short of his duties, and he will probably lack advancement. If, however, as is usually the case, he avail himself of his many opportunities, and under- takes researches to clear up this or the other doubtful point, he becomes favorably known to the scientific world; and in due time, and while he is yet a young man, he is rewarded with a professorship. And so, within a very few years, the Pathological Institute at Berlin has fur- nished from its assistants no fewer than five professors to various universities. These are Hoppe Seyler, Von Recklinghausen, Klebs, Kühne, and Cohnheim ; and the important work that these men have done testifies to the excellence of the system in which they were trained, and according to which they were promoted. Another series of names, though perhaps not so remark- able, could be furnished from the annals of the Physi- ological Institute; and indeed, there is hardly a great laboratory or a great clinique in Germany but can point to similar instances. Again, there are the docenten or lecturers, who reach their position through the same steps as the assistants, and who may have been assistants also. From them, too, the professors are chosen, although this is more the case in the non-medical faculties. Thus it will appear that efficiency in professorial chairs is secured, more than anything else, by the com- pletely organised system in which the rising generation of scientific workers are trained. When an appoint- ment comes to be made, it is usually done very quietly and to the general satisfaction. The other professors of the faculty in which the vacancy has occurred, agree upon some name, which they submit to the education minister. It does not appear that the professors have an actual privilege in this matter, but no doubt their rec- ommendatoin is invited, and is seldom or never set aside. The assistant or docent who has been thus nom- inated, “receives a call” to the professorship, and departs to take charge of an institute, or laboratory, or clinic of his own. He has not canvassed heaven and carth for testimonials; the custom is not known in Germany; and when a German savant receives a letter from foreign parts, requesting him to certify to what he can about his foreign confrère he is as much puzzled as if the request had been for a lock of his hair; he has not issued a bulky volume of those monotonous docu- ments translated from every language under the sun, and gathered together from the remotest corners of the educated world—the more remote the better. He finds, however that his qualifications are known with- out any effort on his part; and those who have nomi- nated him are content to rely on the long and testing apprenticeship which he has served to his special study. In other countries, again, it sometimes happens that natural, or even hereditary, genius is the only thing that can be appealed to.—Brit. Med. Journ., Dec. 30, 71. —-º-e-º- , –, Jan. 25, 1872. EDS. CLINIC : I have received several numbers of “THE CLINIC” in regular succession during the present month. As the first two contained a paper by Dr. , I thought they were sent by him. Two other numbers have come to hand with marks of being sent from the office of pub- lication. If they are sent from the office of publication with the design of making me an involuntary subscriber, pray, please excuse me. I buy and pay for sundry medical periodicals, home and foreign, and really do not desire to increase my expenditures in that direction. If the copy forwarded is intended as complimentary, or to solicit contributions to its pages from myself, that is quite a different matter. Writing out of customary channels of thought and observation, my papers cost me much labor, for it is difficult—exceedingly difficult, I find, to overcome early educational influnces; and so, not get myself confused in writing up life from its facts. The hypotheses, assumptions, traditions, etc., now in use are exceedingly convenient to avoid study. Nev- ertheless, I think I could promise you at least one, but not more than two articles per year. More than that would be accidental and supplemental or exigetic. With this explanation of my wishes in the matter, you can either discontinue The Clinic coming to my ad- dress, if it comes from the office of publication, or con- tinue it, as you please. If it is continued I will regard it as complimentary, and in due time offer a paper for publication in its pages. Very Truly, The publishers were interviewed forthwith. The transmission of THE CLINIC to the above address is discontinued. - —º-e-Gº- I REVIEWS. THE PRINCIPLES AND PRACTICE of SURGERY. By John Ashhurst, Jr., M. D. Philadelphia, Henry C. Lea. 1871.-pp. IO11—Cloth $6 50, Leather $7 50. Cincinnati, Robert Clarke & Co. Leaving out of consideration the masterly work by Prof. Gross, and the very valuable collection of surgical monographs published under the general title of “Holmes System of Surgery,” the works most prominently brought to the notice of our general practitioners and students, during the past ten years, have been those of Druitt and Erichsen. Until the lately issued edition of FEB. 10, 1872.] TIEEE IEH C T , T N T C . 69 the latter edited by Ashhurst of Philadelphia, the Amer- ican reprints of Druitt and Erichsen did not represent, either the actual state of scientific knowledge, or the improvements made in the later English editions of the works themselves. Following close upon his labors as American editor of Erichsen, Dr. Ashhurst has given to the profession a work of his own, in the preparation of which he has evidently availed himself of the recent contributions to surgery made by English and Continen- tal writers, of the labors of American surgeons, and of the clinical advantages afforded him by his position as surgeon to the Episcopal and Childrens' Hospitals in Philadelphia, and U. S. Army Hospitals during the late war. Of the forty-seven chapters into which the work is divided, two are occupied with “Inflammation,” its nature and treatment; two with “Operations in General and Minor Surgery;” two with “Amputations;” thirteen with “Surgical Injuries,” of vessels, nerves muscles, bones, joints and special regions; and the remainder with “Surgical Diseases,” local and general. The chapters upon “inflammation” are of special interest and value, particularly to students, from the fact that they present clearly, and with marked brevity, the pathological views at present entertained, without dogmatically pronouncing a decisive opinion upon ques- tions yet unsettled. For example, with reference to the vexed question of the origin of the pus corpuscle, the author says, “It is even more difficult to speak positively of the origin of the pus cell than of that of the lymph corpuscle. In many cases (as in abscesses) the former seems to originate directly from the latter by a simple liquefaction of the gelatinous intercellular substance of lymph; but in other instances the pus cell appears to have a different source. Virchow and other observers believe that pus corpuscles originate from rapid prolif- eration (luxuriation) of connective-tissue and other nucleated cells; while Cohnheim on the other hand maintains that the sole origin of the pus corpuscle is the migration by amoeboid movements of the white blood-corpuscle through the vascular walls. Finally Dr. Stricker and his co-laborers, while acknowledging the origin of pus cells from both these sources, have shown that the pus corpuscles themselves divide and multiply, and that in profuse Suppurations this is prob- ably the chief mode of pus formation.” In the chapter upon “operations in general,” in reference to anaesthetics, We find the following remarks which are as true as they are worthy of careful remembrance, “It is to be feared that students and young practitioners often get a false impression upon this point, and from seeing the fre- Quency and apparent profusion with which anaesthetics are administered by their clinical teachers, derive a notion that these agents are perfectly harmless, and may be indiscriminately resorted to under all circum- stances. The true rule upon this matter, (a rule which is indeed applicable to all our perturbing modes of treatment), is, that when anaesthetics are not positively beneficial they are injurious. Hence under ordinary circumstances, they should not, I think, be employed except for really important operations, and those which without their use would be tedious and painful.” As respects the choice between the various anaesthetic agents, the author expresses a preference for ether in a very large majority of cases; a preference certainly not shared by the greater number of surgeons; although it must be confessed that the rapidly increasing list of deaths from the administration of chloroform, is causing many an operator to question the propriety of contin- uing the use of his hitherto favorite anaesthetic agent. The relative merits of the different methods of ampu- tating are thus put by Dr. Ashhurst, “If any general rule were to be given, I should say that the circular in- cision or Teale's method gives the best stumps in the fore-arm, the modified-circular in the upper arm and the upper part of the thigh, the common double flap operation immediately above and below the knee, the circular or lateral flap in the lower part of the leg, and the oval operation at the joints.” In this opinion we would most heartily concur, and we are satisfied that there exists, particularly among many civil surgeons, an unjust prejudice against the circular or modified- circular operation. Our author is evidently not very strongly inclined to favor the special antiseptic treat- ment, which has of late attracted so much attention. “As has already been said, the merits of the antiseptic method cannot yet be considered as positively determ- ined. Failure on the part of other surgeons to attain the expected results, is attributed by the advocates of the plan to some mistake or neglect in the application ; and such may doubtless be the case. But it is obvious that any mode of treatment which is so intricate and complicated as to elude the skill of such excellent sur- geons as have failed with the antiseptic dressing, is not likely ever to be adopted for general employment.” We are inclined to think that it is not the intricacy nor complicated nature of the antiseptic dressing that causes the frequent failure in the hands of different surgeons, so much as want of care in the application and unwillingness to devote the time required for such application. So far as our own observation has gone, what is commonly denominated antiseptic dressing, is in no respect a dressing that excludes all undisinfected air from the wound under treatment, in other words, is not the antiseptic dressing at all. Thirty-eight pages are devoted to the consideration of “venereal diseases” which our author considers as three in number, “gon- orrhoea, chancroid, and syphilis.” The unity of the latter affections is claimed by but few writers of the present day, though their diversity is as Dr. Ashhurst says, “even now denied by a good many surgeons, and is practically ignored by a still larger number.” The major part of the book, of course, is devoted to the con- sideration of local diseases and injuries, special refer- ences to which cannot be made within the limits of a review of this character. The work is illustrated with 533 wood engravings, very many of which might have 70 [FEB. 10, 1872. TIEEI IET: C T II INTI C. been omitted without impairing in the least its value. Some of them are old friends, whose faces however have been seen so often and in so many different Works that we really begin to tire of them, friends though they are. One engraving indeed we notice upside down. We fear that some unfortunate student will ac- quire from it rather a queer idea of Bronchocele, and the position and relations of the larynx, trachea, and thyroid gland. Notwithstanding, however such little imperfections, “Ashhurst's Surgery” is of decided value, and better adapted to the wants of students and general practitioners than any other work of its size that has of late appeared. American surgery owes its thanks to Dr. Ashhurst for his very creditable contribution to the professional literature of the country; a contribution in which he has not failed to make due recognition of the labors of his fellow workers on this side of the At- lantic; and these fellow workers will have frequent oc- casion to avail themselves of the numerous statistical tables which he has elaborated and incorporated in the present volume. That the work is issued by Henry C. Lea is a sufficient guarantee of its typographical merits. - PULMONARY CONSUMPTION. By James Henry Ben- net, M. D. For Sale by Robert Clarke & Co. The first edition of this monograph was published in 1866, and was then entirely clinical; it was chiefly de- voted to proving the superiority of the “Hygienic or Sthenic method” of treatment over the old antiphlogistic plan. The progress of medicine now renders this no longer a question for discussion, but the rise and pro- gress of Virchow's doctrine of the inflammatory origin of pulmonary consumption allows the author to review simply the histology of this disease. This new doctrine of neoplastic growths is set aside and the old theory of tubercular origin is adhered to, with the conclusion that age and experience sustains the latter, while “on the other hand, most of the followers of the new ‘inflammation doctrines' are young, enthusiastic physicians full of knowledge but insufficient in ex- perience.” Whether the deposit be tubercular or inflammatory it is merely the evidence of exhausted vitality and gen- eral bodily decay. Such a condition cannot be remedied by medicine; it can only be the “handmaiden” of phys- iology. The author shows from his own personal (he having been a sufferer from this disease) and observed experience, that this condition is curable, and in some cases self limiting, as is evidenced by the old cicatrices found in the lungs in post-mortems of patients who have died from other causes. Whatever objections might be made to the histology of the author, his conclusions in regard to bodily hy- giene, climate, and medical treatment of this disease are sound and represent the views of modern science on this point, TRAITEY DES MALADIES DU FOND DE L'OEIL ET ATLAS D’OPHTHALMOSCOPIE, PAR L. de Wecker et E. de Jaeger. (A treatise on disease of the bottom of the eye and an ophthalmoscopic atlas). The descriptions are given in Wecker's splendid style and the ophthalmoscopic figures in illustration need no COmment. AN Ophthalmological Encyclopedia is to be brought out under the editorship of Profs. Saemisch (of Bonn) and Alfred Graefe (of Halle). They will be assisted by various well known professors and doctors. The work will be divided into two parts. 1.—Anatomo-physiological. 2.—Pathological. - The entire work is to be completed by 1874. CONSUMPTION, ITS PATHOLOGY AND TREATMENT, by Wade Minor Logan, M. D. S. W. Butler, Phil- adelphia, 1871. This little monograph begins with a pleasant preface. “My object in offering this little work “ ” * is simply to afford the results of some observations made, etc.; ” modest, unassuming, preposessing at once. But the text and preface differ materially. To such degree, indeed, as to recall a criticism men- tioned in Forster's Life of Goldsmith. ; “To seek to con- nect the preface in any way with the work prefaced would be generally labor in vain. The moral of it is in a remark of Johnson's when Boswell, admiring greatly his preface to Rolt's Dictionary of Trade and Commerce, asked him whether he knew much of Rolt and of his work, “Sir,” said Johnson, “I never saw the man and never read the book. The booksellers wanted a Preface to a Dictionary of Trade and Commerce, I knew very well what such a Dictionary should be and I wrote a Preface accordingly.” - Any one in the least familiar with the history of the literature of this subject must have been astounded at the claim of originality in its treatment by nitric acid. It is a presumption little short of effrontery, moreover, to parade as new at this period of our century views in pathology which were exploded long before the century was born. • * - While it is true therefore of the book that it is an ancient idea, backed chiefly by antediluvian authority it is true of its author that the work represents an honest effort which is in every sense worthy of encour- agement. There is this dogged striving after personal advancement manifested throughout the book, and as every kind of work conduces to this end the author has already succeeded in raising himself out of the mire of indolence and sloth. If he will only advance in the path he has thus struck out for himself the continued progress of the pilgrim is secure. FEB, 10, 1872.] T H E CIT, ITNTI C. 71 CILINICAL MEMORANDA. Electricity in the Treatment of Tumors. BY PROF. BENEDIKT. Transactions of the Vienna Medical Society, Dec. 31, ’71. Above all things is to be emphasized the progress in the technics of electricity in the treatment of tumors. This consists on the one hand, in the fact that instead of simple cutaneous application, acupuncture needles are in most general use, and this, not only by the uni- polar, but also by the bipolar method; further there is attached to each pole a whole series of needles instead of but a few as formerly. On the other hand, progress is attained by prolonging the duration of the current, and further by employing the different kinds of batteries, as for instance, besides that of Siemens', also those of stronger chemical action as the lead-zinc battery of Frommhold. The speaker exhibits a carbon-zinc battery whose inten- sity can be varied by the amount of fluid present. The most useful fluids are solutions of bichromate of potash and sulphuric acid (1:15). In inflammatory swellings, particularly of the joints, the cutaneous application is preferred. It is to be mentioned, however, that the current is not always to be applied directly to the in- flammatory swelling; the desired effect may also be at- tained indirectly through excitation of the nerves as of the sympathetic, of the spinal cord, of the nerve trunks, etc. For direct applications the Faradic current may also, under proper circumstances, be applied. Fluid accumulations, as sequelae of inflammations, cysts and collections in the various cavities are best treated by acupuncture and Siemens' elements. Barns has stated, however, good effects may be obtained in hydrocele by acupuncture alone. As a matter of in- terest, it is stated that hydatids of the liver have been repeatedly treated successfully by galvanism in the London hospitals. The application of the constant current is perhaps of the greatest value in hemorrhagic tumors. Angioma of all sizes are treated with the best results, usually, indeed, in a single session. The best form of electricity is that which furnishes medium quantity as in the bat- tery of the speaker. The needles of the positive pole are inserted and the other pole is either applied cutane- ously by means of a sponge, or a few negative needles are also introduced. It is essential to perforate at the base of the tumor. It may be mentioned here that “Very arterial hemorrhage produced by the needles or by any other cause may be instantly checked by the insertion of the needles connected with the positive pole. This method of arresting hemorrhage is of great- est value in bleeding after trauma, as it is often much * to check it in this way than to find a surgeon to the negative pole. As. ligate the bleeding vessels. The treatment of aneurisms by electro-puncture has also been materially advanced by the perfections in technic. There has always been fear that the acupuncture needle would open a channel of passage from the aneurism to the surrounding parts. Experience has shown this to be a theoretical objection only. With what impunity an acupuncture needle may |be penetrated into the depths of the body is evidenced in a case of fibroma uteri treated by the speaker, by means of long needles pushed through the abdominal walls; not the least reaction ensued along the canal of passage. The best battery for the treatment of aneurisms is that which, in quantity, is between the Siemens' and the galvano-caustic battery. The most efficient treat- ment is to plunge a series of needles, connected with the positive pole directly into the aneurismal sac. In general it may be stated, however, that the positive pole softens and liquefies, the negative clots and hardens, so that the former acts like caustic alkalies, the latter like the acids. In lymphatic tumors, i. e., swellings of the glands, the best method is the cutaneous application with Siemens' elements, or the acupuncture needlesin connection with Under this treatment, depressions are produced in the tumor, it is broken up, in other words, into smaller tumors and gradually total dissolu- tion is effected. The stronger chemical batteries are apt to cause ulceration and suppuration, and are, therefore, to be avoided. Chvostek has obtained excellent results in the treat- ment of indolent buboes. Numerous observations con- firm the benefits of this treatment in strumous swell- ings. The cutaneous application is often sufficient here. In many cases, most especially in cystic goitre, acu- puncture should be practiced in the same way as in glandular swellings. In that form of struma known as Morbus Basedowii, diminution of the swelling is obtained by galvanizing the sympathetic. The good results here are not to be referred to direct effects of the current as they are manifest after relatively feeble currents of short duration. In the treatment of neoplasms Prof. Groh, of Olmütz, deserves, according to Althaus, particular mention as many of theimprovements in technic are of his device. Benign tumors are much easier dissipated when the base is brought into a condition of necrosis and mor- tification. In carcinoma it is necessary to operate with the strongest currents of an hour or longer duration. To effect this the patient must be narcotized, as by morphia hypodermically. If feeble currents of short duration be used the growth of the tumor is stimulated; it increases then more rapidly than it is destroyed. The speaker has arrived at this conclusion from his own ex- perience and this conclusion has been confirmed, recently by others—that electrical excitation may stimulate these neoplasms to more rapid growth. Neftel of New York created quite a Sensation with his statement that he had cured a cancerous tumor of the size of an orrange and dissipated the cancerous cachexia in a few sessions. This 72 [FEB. 10, 1872. THE CLINT c. case is to be regarded as a remarkable exception to the rule as his patient seems to have been able to endure a great number of Siemens' elements without narcosis, what is certainly not usually the case. The unhealthy appearance of a patient is surely not always to be considered a cancerous cachexia. Neftel's method must be regarded as insufficient for most cases as in the first place so many elements can not be borne without nar- cosis, and in the Second place, unipolar puncture is sel- dom enough; the Siemens' elements further are not emergetic enough in effecting destruction. By means of the method above described Groh has cured thirteen of seventeen cases, several in a single session. . Groh has also cured two benign neoplasms of considerable size and one carcinoma of hazel-nut size by means of frequent applications, of several hours dura- tion, of weak currents of the Daniel's battery. The great advantage of electricity in the treatment of cancer is the total absence of loss of blood and of all reactionary manifestations. Moreover electrolysis may be further applied in situations where the knife would be danger- ous or when there would be risk of opening internal cavities. Whether treatment by electrolysis is more exempt from recurrence of the disease than treatment by operative proceedure is a question still subjudice. The experiments of Tripier and Malez in the treat- ment of strictures created at the time no little sensation. They effected cure in a whole series of cases very rapidly, often in a single session of but few minutes duration. | They used the Siemens' elements with a covered catheter connected with the negative pole and brought into con- tact with the cicatrix. Less favorable was the experience of Couriard, of St. Petersburg, who lost one case from pyaemia resulting from this treatment. The speaker has not had the op- portunity of collecting results in the treatment of cases of cicatrices in general or in special of strictures of the urethra. At least it must be said that this method of their treatment is not without danger, as the urethral wall may easily be severely cauterized; strong currents, therefore, are to be avoided. —-º-º-º- I HOMHE NEWS. * The Commencement Exercises will be held on Friday Evening March 1st. Ninety-one Candidates have registered for examination. - A bandaging contest was held at the Good Samaritan last week for a prize of a complete case of Surgical in- struments offered by Prof. Dawson. Eleven contest- ants entered the lists. Drs. Mussey, Juler and Dandridge were appointed referees. The general excellence displayed is best exemplified by the fact that the jury were unable to decide between five students, Messrs. Brown, Blackstone, Plummer, Lyle and Lockhart. Lots were drawn and the laurel fell upon the brow of Mr. T. Blackstone of Bainbridge, Ross Co. Ohio. Medical CoHHege of Ohio. SPRING c 0 U R S E. The regular eight weeks course of practical instruc- tion for the Spring of 1872 commences March 15. Un- usual advantages are offered this year in the fact that the course will be conducted by the entire Faculty of the College. - - The course will embrace the following topics: Clinical Medicine—Bartholow. “ Surgery—Dawson. Anatomy Brain and Nervous System—Gobrecht. Operative Surgery—Conner. “ Obstetrics—Reamy. “ Ophthalmology—Seely. Female Pelvic Surgery—Palmer. TJrinalysis—Nickles. Physical Diagnosis—Cleveland. Fractures and Dislocations—Kearns. Genito-Urin. Dis.—Anderson. Microscropy—Whittaker. Prof. Graham will deliver occasional lectures on Clin- ical Medicine and Diseases of the Chest during the pro gress of the Course. The design of the Course is to present instruction in a thoroughly practical manner. Physical Diagnosis is to be demonstrated in the hospital wards; Operative Surgery, Operative Obstetrics, Operative Ophthalmology, and Operative Gynaecology on the cadaver. - The Dissecting Room will be under the supervision of Dr. where abundant material will be provided. Special attention will be paid to the chemical and mi- croscopical analysis of morbid urine. In order to render this course the most practical pos- sible, an opportunity will be afforded each individual of the class to make the various examinations and opera- tions on the living and dead subjects. Regular daily Medical and Surgical Clinics will be held at the Good Samaritan Hospital: Two Daily Clinics will be regularly held in the Cincinnati Hospital, throughout the entire course; and a Daily Clinic will be held at the Dispensary of the Medical College of Ohio. One hour each evening will be devoted to Recitations on Anatomy, Physiology, Practice, Surgery, Obstetrics, and Materia Medica. The eminently praetical nature of this course, and its shortness of duration, together with the great clinical advantages presented in Cincinnati, can but commend themselves favorably to the practitioner as well as the student. - FEES FOR THE ENTIRE CourSE, $10 As this Course does not count towards graduation, being considered supplemental to the regular winter course, graduates of the College are not required to matriculate. The matriculation of non-graduates is deducted from the fees of the ensuing winter session. :- F. E. SUIR F. - E. S. WAYNE IET. THX. Suire & Co., WHOLESALE DRUGGDSTS, M. A.IN UFA CTU. R.I.N. G. pHEMists AND PHARMAceutists, CINCINNATI, OHIO. Have constantly on hand a full assortment of sye), Ecºexex, Yoº J Gºs ANOO woex,xc)(N)es, cºery)(XCA), Alex’AkkAºcus, TESTs, MEDICAL, GLAss warE, &c, &c., And solicits the patronage of the trade and profession. we would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, ti Made in accordance with the U. S. P. and other recognized authori- ÇS. - - ETINIFD AND EARH, CHEMICALs, Of the popular class of preparations known as II, T, IIXIII, s, We manufacture a full line. Those of our make may be relied 5pon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. Bitter Wine of Iron, An excellent Chalybeate and tonic, Wine of Iron, &c. AGENTS FOR BULLock & CRENSHAw's Sugar-coated Pills and Granules. ) - * Lists of preparations and of Sugar-coated Pills sent by Mail wºn *PPication. The long standing and well and widely known repu- *tion of our house we offer as a guarantee for the reliability of our **on, and the quality of the goods sold by us generally, |TIER, S.INT.INMA ERSEI mºll Eº JAMES FOSTER, JR., & Co. Instrument Makers and Practical Opticians, Beg leave to return thanks for the patronage extended to them through a long series of years (having been established since 1836), and in the reorganization of their firm will endeavor to merit a continuation of the |same. We wish it understood by the Profession and the Public generally that our invariable rule is, to make or import none but the best in- struments. Those in want of any of the acknowledged good aids of vision to imperfect eyes, will always find the best and largest stock of Lenses, Spectacles, and the best models procurable, with pains- taking skill to adjust them to all conditions of sight, at our house. Special attention paid to orders for Fine Microscopie Objects and Microscopic Apparatus, Magnifiers and Readers in great variety. edical Batteries, Barometers, Thermo- meters, Hygrometers, Urinometers and Rain Gauges, of the most approved construction always on hand. All orders promptly | and accurately filled. JAS. FOSTER. J.R. & F. S. SEACKEEford, ! ** JAs. FostER, JR. & co. S. W. Cor. Fifth & Race Sts., Cincinnati, 0. S 2 Ke TRUSSES. 392 No. 758 BRoadway, New York I HAVE been in the habit of applying and recommending the Truss : manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined. LEWIS A. SAY RE, M. D. Surgeon, Bellevue Hospital. From Prof. Willard Parker to S. D. Townsend, M. D., Surgeon to the Massachusetts General Hospital. BEG leave to state for the benefit of all concerned, that I have known Dr. S. N. Marsh the last fifteen years. * * * I am in the constant habit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with any of the risks to the patient that exist in many of the plans suggested and attempted to be carried into execution. I have confidence in Dr. Marsh as a gentleman of honor and integrity, and as such recommend him to the members of the medi- cal profession generally. WILLARD PARKER, M. D. Professor of Surgery, New York City * Dr. S. N. Marsh's Patent Radical Cure Truss, and all other kinds of |Trusses, Shoulder Braces, Supporters, Elastic Stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Cure Truss Offices of S. N. MARSH & CO., No. 2 Vesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. OPPOSITE THE HIGH STEEPLE, HMHillſ. Wilſº twº SAML. P. THOMAS 167 EAST 34TH-ST., NEW YORK, By Special Appointment Electrical Instrument Makers to the New York State Hospital for Nervous Diseases, MANUFACTURERS OF PORTABLE ELECTR0-MAGNETIC MACHINES, º Portable Galwanic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, 1870, and May 30th, 1871. These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery Fluid. |M|| |||||—|| |||||||} PERMANIENT BATTERIEs, For Hospitals and General Practitioners, IETIECTIER, CIDIES. For Eye, Ear, Larynx, Nose, Uterus, Vagina, Bladder, Rec- tum, Feet, Phrenic and Sympathetic Nerves, Elec. trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. - EXTRA (4TS FROM THE OPINIONS OF THE MOST JEI/IIIN ENT MEMBERS OF THIE PROFESS / ON. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “Nothing CAN EXCEED THE EFFICIENCY AND CONVENIENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” - We are authorized by Prof. Hammond to announce en- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- proved and re-modified Instruments made by our Company. * MEREDITH CLY MUER, M. D., Prof. of Diseases of the 'Ner- vous System and of the Mind, &c., &c.—“I consider theºr Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prºf. of Surgery, St. Louis:—“In neat- ness, compactness and efficacy, they can not be excelled.” A LFRED C. G ARRATT, M. D., Boston :-"In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” - Similar Testimonials have been received from JOHN J. CRANE, M. D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A. MURRAY, M. D.; CHAS. E. BLUMENTHAL, M. D.; E. C. SEGUIN, M. D.; ALLEN MAYNARD, M. D., Cleveland, O.; Dr. C. WANNIE, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES KELLY, Florence, O.; Dr. JOHN BECKER, Brighton, Iowa; Dr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes- barre, Pa.; JOHN J. CALDWELL, M. D., Brooklyn, and many other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an Electrical Instrument for medical purposes. CALL OR SEND FOR CIRCULAR AND PRICE LIST. j IDEALER IN English, French and Scotch GOOD's, 34 West Fourth Street, ("Z.W*("A.W.W.??"/. Fosrº-R's, IE'_A_TIEHINTT Are furnished to Officers and Soldiers on Government a CCount. - I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMES A. FOSTER, 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cincinnati, Ohio, or 172 Jeff- ferson Avenue, ioetroit, ñrich. - O ID O E L E S S A. N. D. P.A. L. A. T A E II, E. In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERs & BARTLETT, of Portsmouth, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. - - Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachitic Affections, in Chronic Rheumatism, &c. - The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. * We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. “We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for ** in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. List of Pharmaceutical Preparations, MANUEFACTUREED BY Jonºv wrºza e amozwan, FEIILADELPHIA. -º-h ELIX, PHOS, IRON, QUININE AND STRYCHNIA, * - ELIXIR OF GENTIAN FERRATED, ELIXIR WALERIANATE OF AMMONIA, s (Goddard’s Formula,) ELIXIE VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, Iron, with Phosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Iron, Peruvian Bark and Choice Aromatics, .” ELIXIR OF CALISAYA BARK, ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, . . COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER WINE OF IRON, . . . . Citrate of Iron and Peruvian Bark, FERRATED CORDIAL ELIXIR, ELIXIR CALISAYA BARK, WINE AND BISMUTH, ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, - FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, - - TASTELESS COD LIVER OIL, TASTELESS COD LIVER OIL. FERRATED, - BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and Sherry wine, ELIXIR WALERIANATE OF STRYCHNIA, WINE OF PEPSIN, SYRUP SUPERPHOSPHATE OF IRON, ELIXIR OF BISMUTH, COMP. FLUIDEXT, BUCHU AND PAREIRA BRAVA. STUTEPEPOSITOTER, ITES. Rectum, Vaginal, and Male Urethral Suppositories and Soluble Pessaries of Pnre Butter Cacao, made with great eare, and of every variety of combination. Lists sent on application. SPONGE TENTS.—For the Urethra, of every size and style, made of finest quality of sponge. MANUFACTURING COMPANY. MANUFACTURERS AND IMPORTERs of AND Window Shades, 37 Wasr Fowarm scºrer, CINGINNXT, 0. H. H. BRENEMAN, Proprietor, IRT S Made to order of N. Y. M. Muslin and 2300 HEAVY Linen, per dozen - - - $26 00 Wamsutta Muslin and 2100 HEAVY Lin- en, per dozen - - - - - - - - 33.00 Wamsutta Muslin and 1900 Linen, per doz. 30.00 Lonsdale Muslin and 1700 Linen, per doz. 27.0) First three qualities have ALL LIN EN Cuffs and Neckbands. At above prices Cuffs are attached. Same quality of our own manufac- ture, ready-made, $3 per dozen less. Perfect satisfaction given or money cheerfully refunded. - - - ... Also import and Manufacture Men's Furnish- ing Goods. - Pilce’s Opera-House, Fourth Street, Cincinnati; 9s 1 || Wabash Avenue, and SS West Washington Street, Chicago. M A R K TVA IN'S NEW E O OIX IS NOVV READY FOR CAN VASSERS. It contains over 600 pages of reading matter, with 250 engravings, designed expressly for this work, by the best artists in the country. Agents now at work upon it are meeting with unparalleled success. Agents at Circleville, O., reports 25 orders in 2 days; one at Louisville, Ky., reports 175 orders in 8 days; one at Middletown, Conn., reports 200 orders in 12 days; one at Cincinnati, O., re- ports 250 in 12 days. Early applicants secure choice of territory. For circulars, terms, &c., address NETTLETON & CO., 161 Elm Street, Cincinnati, O. BASCOM & CARPENTER, Stationers, Printers -AND- - Blank Book Manufacturers, 136 VINE sºl{REET, &\\\\\\\\\\\e E. D. ALBRO & BRO. IMPORTERS AND MANUFACTURERS OF FOREIGN and DOMESTICwOCDs In Veneers, Boards and Plank, frºnt-Maºri', 'al-Biliń'ani Star-Billiº, The only house in the Western country that saws Spanish and Mexi- can Cedar for Cigar-Box Makers We import our own wood direct, and can sell at prices to compete with any and everybody. Also saw and keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. office and warerooms, 136 and 138 West Second Street, veneer Min, 507, 509, 511, 513 & 515 W. Sixth St., CINCINNATI. S M | . f t§ ; * .* -% **-* * ºrs | -.R -º ~ *%; |w =|º ;: =|i -- -; i ºſº i. - #. ;Niš i. || :". IIIſ * : * - t #1; # || || º!. º -------- ſlºt. Eºtº: -- E== .# [2S ºft Yllſ. TY || || || || || zº a ‘tº ; : - . . |: 4. . ſº º 5- . º e- . . |--------- ºś :=>º-ºº::=>::=::Eº-º-º-º: s , rºº ==#######3:#E:::::::::::::::: *: ==ºfflº --->E E*-ºs- E->s-ºr- FºE #EEÉ: ------ CINCINNATI. E" A C TUſ I, T Y - - J AM E S G R A H A M, M. D., DE AN., Frofessor of the The Ory and Fractice Of IMC edicine and Clinical IMedicine. ROBERTS BARTHOLOW, M.D., W. W. DAWSON, M.D., Professor of Materia Medica and Therapeutics. 1 Professor of Principles and Practice of Surgery and Clinical Surgery W. H. GOBRECHT, M.D., . C. D. PALMER, M.D., Professor of Anatomy. Professor of Medical and Surgical Diseases of Women. P. S. CONNER, M.D., T. A. REAMY, M.D., Professor of Surgical Anatomy. *. Professor of Obstetrics and Diseases of Children. W. W. SEELY, M.D., - JOHN L. CLEVELAND, M.D., Professor of Diseases of the Eye and Ear. Demonstrator of Anatomy. SAMUEL NICKLES, M.D., CHARLES KEARNS, M.D., Professor of Physics and Medical Chemistry. - Assistant to the Chair of Surgery. J A M HE S T - W H ITT A. EX E ER, , Frofessor of Physiology and Secretary of the Faculty. ºr "T"-- T. LOUIS BROWN, Prosector of Anatomy. - Janitor, College Building, Sixth St., bet. Vine and Race. Printed and Published by NoFR1s & M URRY, Medical College of Ohio Building, Cincinnati. PUBLISHED IEVERY SATURDAY. TERM s—$2.00 $l. Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editor : •. . " " . . . . . All Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer. Vol. 2. C IN C IN N A TI, F E B R U A R Y 17, 1872. No. 7. JAS. T. whitTAKER, M. D. Editor. | No. 101 West Ninth Street, Cincinnati. Associ..A.T.E. E.D.I.ToIRs. W., W. Dawson, M. D. Thad. A. REAMY, M. D. P. S. CöNNER, M. D. C. D. PALMER, M. D. W. W. SEELY, M. D. SAMUEL NickLEs, M. D. CHAs. KEARNs, M.D. JNo. L. CLEVELAND, M. D. Roberts BARTHollow, M. D. :- W. W. SEELY, M. D., & * * - • - º º Tarasunen. • No. 118 West Seventh Street, Cincinnati. - C L U B “R AT E.S. ; 4 Copies to one address - $ 7.00 6 {{ ç ç. 10,00 12 4 & &&. 18.00 | C O N T E N T S. ==º Page ORIGINAL ARTICLEs The Acid Treatment of Rheumatism by D.T. Gilliam M. D.....…78 - Treatment of Dysentery by Ipecac Enemata by H. V. Ferrel M. D....74 TRANSLATHON - - Cancroid, Impetigo, etc., Their Diagnosis and Therapy, by M. A. Duvergie, (From the Bulletin Therapeutique, Nov.30, 1871)........74| SCIENTIFIC NOTES Vaso-Motor and Trophic Neuroses—The Chemistry of Hail—Fecun- dity of Germs 76–79 MEDICAL NEWS Charles Lever on the Medical Profession—German Provisions for Science—An Error of the Empire—The Revealer of Anaesthesia —The Würzburg Clinic—A New Field for Hoppe Seyler—Death of Jaeger—Honors to Dr. Cormack—Chloroform an Ineligible Agent for Robbers................................................................. 79-80 - correspond ENCE Letter from Vienna—The Diagnosis of Syphilis by the Microscopic Examination of the Blood...............--------------------------------------, 80-81 Books and Pamphlets Received....................................... 81 - CLINICAL MEMORANIDA, Phrenic Neuralgia—Intestinal Obstruction treated by Ice—Extract of Meat—A Case of Acute Cataract—Treatment of Pruritus Vulvae—Hot Baths in Hydrops—Indications for the Employ- ment of the Catheter in Old People—Antidote to Carbolc Acid —Opium in Phagedæna–Fistula for Cystitis......................... 82-84 * NºWs................................................................................ 84| THE discovery of peculiar germs in the blood of syph- ilitic patients, described elsewhere in our columns, is creating a profound sensation throughout Europe. If confirmed by future researchit becomes one of the greatest triumphs of scientific medicine in the nineteenth century. THE CLINIC will keep its readers posted in the rapid Fashionable Hatters, H.A.B.EES' Fürs, 92 wrest FOURTH ST. opposite Post office, - CINCINNATI. *special Inducements to Medical Men. Bº § RAVERSonwooDºº ºss ºf 32 WºST:FOURTH Sºº--ºl J. TAFT, Editor Dental Register J. & W. TAFT, TENTIsTs 117 WEST FOURTH STREET, CINCIN NATY, O. Begisters A Monthly Journal, CONTAINING 48 PAGES, development of this subject which is sure to ensue. Devoted to the Interests of the Dental Profession, ROBT CLARKE & CO. William Autenrieth, PUBLISHERS, ||N&SHillſ, No. 65 WEST FOURTH STREET, Call the attention of the Medical Profession to their Extensive Stock of &nglish, Āmerican and £venth arrozczz poors. 'Paying particular attention to this branch of their business, they are enabled to execute all orders on the shortest notice, and at the most || reasonable rates. Their facilities for the impor- tation of FOREIGN BOOKS, THE PROCEED- INGS OF SOCIETIES and HOSPITAL RE- PORTS are unsurpassed, and any orders en- trusted to their care will be filled promptly, and at the lowest rates. Subscriptions received for FOREIGN and AMERICAN PERIOD1CALS. - All the New Publications received as soon | . as issued. - Letters of Inquiry will receive our prompt and full attention. Catalogues furnished gratis on application. ROBERT CLARKE & CO., lºwhºlºmºn, hill; PRINTERS AND BLANK BOOK MANUFACTURERS, 2ealers in Zaze, .2/edica/, ZŽeo?ozical, Schoo!, azed.747sce//azzeozºs Zºoožs, 65 West Fourth Street, CINCINNATI, O. |No. 71 west sixTH stEEET, . BETWEEN WAISUT Añº VINK, cincinnati, ohio, MANUFACTURER OF AND DEALER IN III III III'll IIII Abdominal Supporters, Trusses, GLUB-F00T SHOES, SPINAL APPARATUS, ETC Keeps constantly on hand a full variety of Metalie and Eubber Syringes, Stomach Pumps, Etc. STOCKINGS FOR WABDGOSE WEDNS, Special attention given to the fitting of Apparatus for Deformities. lar Agent for Dr. L. A. BABCOCK's silver Uterine supporter, -ALSO– DR. AHL's POROUS FELT SPLINTs, -—ALSO– DAY's spi, INTs -ANIO- S. W. Elliott’s Saddle-bags - - - *—-- ~ : ~ : - "". tº-sº-º-º-º- --- * -º- ºs- -*-*-*. •- - - * *-*-m-º. **'. --- .*------------ **- t- - - ,---------------- ſ as º ºsmºs---------------sº ſ *-*-m-tº-m-tºmº-mº —cy == - *=----------"- * * sºme------" - # ==#| || -. : ºffiliffſhºhº. . F. ɺft : Hºmº º -- at-i-Eššjā; |##### - EEE İ | ;: # l | | . . º AS Lº-> ---E |Hiſ - C ---- firiº - d º # | º ºr:ºs ===} | ſº # | i. º jºº ~ §5-jiljºš |Hiſſiliji i. &ºiſ: § # =#| || §§§ Sºśc ſ §§ . . . . *::::, . " | g º º º 2, ºr ºt #3:22. ſº Sºś º | | | Hºſſilſ: 322:35:Sºº |º Mºś | L - | | | |. *…] : .23% ºsºſ sº-º- º- $2. §§ º - rº-º-º: F. : º ºš ŠºšSº º: S$3;S㺠| | | ||||||}º #3 ºiliº §: º | |||||Kºłº F- Tºº 3||||}|3 #$º |...} : : - }; º Hº - §: É - º tººlſ: - §:#= É$ F: ºº::=º: ######$$$ºś º ####$ºś ºf º – ºšššŠ 3. * * 3% ##### - sº º W “s.º & ſº § Sºśº: & 22.". * A A' Sº, ... º.º. > 2.4%º % at - 㺠% 2.2 º S-S-2 SS; -- = Hºsº-Slºss 2 + ſ^2; º - º ==Sºšć% #%= - - - Esº->=S =sº % | ”*- == Sº? *Z- GooD s AMARITAN HOSPITAL. The GOOD SAMARITAN HOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner of Sixth and Lock streets. It is handsomely furnished througho", and is provided with all the necessary ap- pointments of a First-class Hospital. Porticoes, with commanding views, surround the whole house, and wide halls and abundant windows secure that full and free ventilation which is so essential to health and comfort. Service is furnished by the SISTERS OF CHARITY, Under the Superintendence of the well-known SISTER ANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. r Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each Professor presiding over his own especial department. Patients may, however, select from the regular profession of the city any physician of their choice. * The GooDSAMARITAN HOSPITAL presents extra inducements to Invalids throughout the State as a safe and quiet asylum in any case of protracted illness, or in cases, more particularly, requiring Surgical Operation, where some stay is necessary in after treatment. Rooms vary in price, according to the character of appointments necessary and service required, ranging, in general terms, between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand of B& Address, sISTER ANTHONY, |Hospital of the Good Samaritan, corner of sixth and Lock Sts., Cincinnati, Ohio. º sº ||Nº||RTS vºy WºZN N 82 Carriage Manufacturer, Nos. 9 and 11 East Sixth Street, bet. Main & Sycamore. I MAKE NOTHING BUT A"//*S 7" C.A. & S.S. W’0/PA’, Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. • My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of * LIGHT FAMILY CAFFIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive variety of light elegant designs of different cost and finish. In vehicles especially adapted to PHYSICEANs' Use. The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I Enake for that purpose. The superiority of my light gentlemen’s buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price lists furnished on application. References to Dr. W. W. Dawson and all the leading Physicians in the city and heighborhood. n. Wilson McGrew, wo. 27 m.a.sr Forrrrr Srnarr, PIKE's OPERA HOUSE BUILDING, Importer and Dealer Diamond and Gold Jewelry, Watches for Ladies and Gentlemen, Sterling Silver Tableware, Bronzes, Antique and Modern; Marble and Bronze Clocks, Marble Statuary, G E N E R A L L Y. DIVIDED MEDICINES, The Divided Medicine Com’y, CINCINNATI, OHIO. The Company have the honor of bringing to the notice of the Profession, this NEW AND ExcEEDINGLY PRACTICAL METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. - The Divided Medicines are prepared by FREDERICK KRAUS, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and NO MORE. The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every square will consequently contain accurately measured quantities. But not only SoLUBLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINES. * This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, ; 3. #. sh. io. and even idbo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. - Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE TO SPOIL BY ANY LENGTH OF TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. - Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calis with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. For Samples, Price Lists, and Agencies, address §§ .# tiºn |S The Divided d IBOX 2688, Or FRFDERICK KRAUS, Chemist and Druggist, Walnut Hills, Cincinnati, O. MR. FREDERICK KRAUs: CINCINNAT1, February 15, 1871. - Dear Sir—The specimens of your “Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: SUI, PII:MORPH II....................... % grain in each square. ARSENACID.......................... 1-20 grain in each square. “ CHI IN INI ....................... 1 * * * * $6 CALOMEL.............................. 34 “ “ $ & tº º goPPER ........................}% { % RespecTFULLY Youns, E. S. WAYNE, Analytic Chemist. f T H E CI.I.N.I.C. Vol. 2..] S A T U R D A Y, F E B R U A R Y 17, 1872. [No. 7. O RIG IN A L A RTI C L E S. - 3 - - - ACHID . TREATMENT OF RIHIEUMIATISM. BY D. T. GILLIAM, M. D. Nelsonville, Ohio, It is not so much the intention of this article to in- troduce an innovation in the treatment of this disease, as to call the attention of the profession to certain facts, which I conceive to be of importance thereto. Our present accepted ideas of rheumatism are, that it is a disease of the blood—that the circulating fluid con- tains a materies morbi which gives rise to the various phenomena witnessed in the disease. Prout goes so far as to name the offending matter. His theory is—and it is only theory; having as yet never been satisfactorily demonstrated—that lactic acid is the morbific agent. The theory is good, and is so plausibly sustained that we are fain to accept it. .- . On these premises we base our so-called rational treatment. But while we endorse Prout's theory, and adopt the alkaline treatment as being that rationally indicated, we still cling to other methods of treatment, that are not rational as it seems to us, simply because they yield us good results. These are the less rational, but but by no means the less useful. - The object of this article is, to show that certain remedies heretofore used as empirical, are as justly en- titled to the appellation of rational, as many that are at present considered as such. & Now lactic acid in certain proportions exists in the blood as a proper constituent, and consequently its mere presence there cannot be considered as deleterious. But if it exist in disproportionate quantities, then we may believe that it exerts a bad influence. If, then, it be superabundant in the blood, it is so from one of two causes, if not from both together; 1st. It is because it is not metamorphosed or expelled from the system as it should be; or, 2nd. Because it is produced more rapidly than it Ought to be. - If it depend on the first condition, what are the in- dications of treatment? Evidently to promote its expulsion, or destruction, or its change into those principles into which it normally resolves. To promote its expulsion is not easily directly attain- able. But to destroy it, or promote the retrograde metamorphosis, if indeed it be a retrograde process—is not so difficult. Being an acid, we feel confident that it can be neutralized by an alkali; but while we are attempting to neutralize it, we are fulfilling the other indićation, viz., promoting its normal metamorphosis. This is clear enough when we consider how this change is wrought; the lactic acid after having played its part in the economy seeks an alkali with which to combine, (the free soda of the blood) and the resulting compound being oxidized, carbonate of soda and water is formed. Hence the use of alkalies in this condition is right, and proper, and eminently rational. So far allis well; but let us go on and see if there be any other phase of the subject. There are doubtless cases in which the second condi- tion obtains—where the lactic acid is produced more rapidly than it should be. Given, a case of this kind, what now are the indica- tions for treatment 7 Without hesitation we should say neutralize it—give the alkali. But such a course would be eminently improper. In order that we may understand why it would be im- proper, it will be necessary to ascertain what forces are at work to produce this excess of lactic acid. Lactic acid is derived from glucose, and glucose is derived from a great variety of sources. - The change from glucose into lactic acid is a natural transition, and is facilitated by an alkaline state of the blood. “Dr. Pavy conceives that particles of fibrin under- going change or decay constitute the natural ferment which converts glucose into lactic acid. An acid state of the blood is found to hinder this metamorphosis. (Headland on Medicines, pp. 128). Miathe affirms; “the natural transformation of glucose into lactic acid is hindered by tendency to acidity of the blood;’ and then, “the presence of an alkali is necessary to this transformation.” (Ch. Appliquée, pp. 75). Hence if we would prevent, or retard, the formation of lactic acid, we must reduce the alkalinity of the blood. It may seem paradoxical to advocate the administra- tion of acids to correct acidity of the blood, but is prob- ably not more so, than to administer acids for acidity of the stomach; a practice, the utility of which, will hardly be called in question. Acids have been used in the treatment of rheumatism and have yielded results the most gratifying. The books are full of enconiums on the excellent virtuºs of lemon juice as an anti-rheumatic; but some in their inordinate love for rationalism, seeing and acknowledg- ing its excellencies as a therapeutic agent in this dis- ease, have convinced themselves that black is white, and that lemon juice is not acid but preeminently alkaline. Then again most agree in using an alkali combined with an acid such as the acetate of potassa 74 T IEI IET C T III. TNT I C - [FEB. 17, 1872. in preference to the free alkali, claiming that they get better results. It would be a pleasant, though perhaps not profitable task, to trace these salts through the system, and note how speedily and effectually the alkali is expelled from the system, while the acid is retained and utilized. I have purposely refrained from alluding to the excellent influence acids exert over fevers and inflammatory affections in general, but in the Selection of our reme- dies all these things should be considered. The question now is, how to distinguish a rheumatism depending on a condition where the alkaline treatment is indicated, from one calling for acids. At present this is hardly possible, but when we con- sider that the animal economy is furnished with ample facilities for throwing off effete and deleterious matters, we may rest assured, that if the excessive supply of the offending matter be cut off, the system will quickly rid itself of that which remains. —-º-º-º- Treatment of Dysentery by Hpecac Rºmelmata. BY H. W. FERRELL, M. D. Carbondale, Ills, The Am. Journ. Med. Sciences, Jan., 1872, p. 254, notices an article from Dr. Jessop, in The Indian Med. Gazette, upon the use of ipecac by enema for the cure of dysentery. In July and August, 1870, during an epidemic of that disease in this section I treated thirteen cases of acute dysentery; the first and second in the usual manner. The first recovered, the Second, a child, aet 18 mo., died. The third and fourth, parents of the child (their other child had already died of the disease under the common treatment by another physician), were treated with lead and opium till I thought they too would die, when I decided to use ipecac. It was administered as follows: B. Pulv. Ipecac. 3i.’ Mucilag. Acacia, 3 vi. M. Give as Enema. This was repeated three times a day for three days, when a complete cure was effected. In another case, male, aet 40, its benefits were even more strikingly dis- played. Of the thirteen cases, two were treated with- out igecac ; one recovered and one died; three were evi- dently saved by it after the most approved treatment had entirely failed. In the remaining eight cases it was used early and alone, and in none did any symptoms arise betokening great danger, In July last I treated Mrs. I., widow, act about 50, for sporadic dysentery. Ipecac was administered per enema, and she made a hasty recovery—in her case, to relieve the excessive tormina, gtt. xv. fl. ext. hyosciami were added and had the desired effect. Dr. Jessop gives 10 gr. of the powder with 3.SS tr. opii in 3ii arrow root decoc. or mucilage three times a day. I have never given to an adult less than 60 gr. of the powder and in 3 vimucilage acacia or slippery elm which is as good and can often be obtained when others can not. —sº-º-º-o- Cameroid, Noli-Me-Tangere, Ulcerous HImpetigo Rodems, and Non-Ulcerous Impetigo Rodems. Their HDifferential Diagnosis amad Therapy. 13Y M. A. DEVERGIE. Member of the Academy of Medicine, Honorary Physician to the St. Louis (Paris) Hospital, From the Bull. Therap., Ncv. 30, 1871. In 1854 in the first edition of my “Treatise on Dig. eases of the Skin,” I thus expressed myself in reference to impetigo rodens; “This is a form of chronic impetigo very badly described, I might indeed say unknown, of which French writers have treated very imperfectly, or have not treated at all. I have had my attention di- rected to it for Some Seven or eight years, originally by a patient who had been suffering from it for nine years, and had been under the care of all the dermatologists in Paris, without obtaining relief.” In 1854 I had described three different forms of impetigo rodens, two non-ulcerous, and the third ulcerous, and had established several characteristics which serve to distinguish the latter species, (wlcerous impetigo rodens,) from noli-me- tangere. Since that time I have constantly studied this disease, and have established its treatment according to its varieties. If Alibert does not speak of impetigo rodens, he confounds its forms in the descriptions that he has given of the “dartre rongeante.” Willan & Bate- man (Ed. 1820, p. 204) devoted only a few words to this affection, which they have however des- ignated by name. What they do say, shows that they had but very imperfectly observed it. Their first Sentence proves this; “This variety of this disease stub- bornly resists the treatment employed; without doubt, because of the cancerous affection with which the cellular tissues and skin are attacked.” Rayer, Cazen- ave, Bazin, Hardy, make no mention of it in their works. M. Gibert devotes a short article to impetigo rodens, the seat of which he places upon and about the nose; but he very soon confounds it with certain forms of lupus. As to any special treatment of this variety he says nothing. The four affections embraced in the title of this article have between them correspondencies that I endeavored to establish in my “treatise on diseases of the skin,” as the result of the special observa- tions that I had then made. Time has enlarged the circle of these facts, and unhoped for cures have been FEB. 17, 1872.] TIEEI IET: C T , IIINT I C - 75 added to cures effected in diseases less grave; divers means, that I have employed since 1852, have enabled me to secure success more and more determined. It is this which has decided me to publish this new paper, and to call the attention of my fellow practitioners to these singular diseases in their but-little-known forms. Surgery applies to them too often the knife, and Med- icine dares not touch them, but confines herself to ad- vising the use of topical remedies which produce no effect. I shall first endeavor to establish between these affections the morbid differences, which will enable us to characterize them, and distinguish between them ; and shall then lay down a basis for their treatment, with such details as the subject may demand. The cancroid affection may be defined (regarding simply its appear- ance) as an ulceration of the skin, having its edges indurated, granular, mammillated, and resting upon a base, indurated in its centre as well as its circumference. Thenoli-me-tangere is nothing else; I mention this name in order to show that it is a synonym of cancroid disease and that we may not be compelled to return to it again. But if cancroid presents itself to our eyes under the form of an ulceration of the skin, having indurated edges, the disease that I have called ulcerous impetigo rodens presents often times conditions and an appearance very similar. However, it seems to me, the cancroid differs from the impetigo rodens in several respects. First. Not only in the cancroid is there induration of the edges of the sore, but the induration involves the whole surface; the ulceration rests upon tissue whose indura- tion is more or less strongly marked, so as to make the cancroid approach in character true cancer; in the wlcerous impetigo rodens the induration is found only in the prominent edges of the ulcer. Second. The appear- ance of ulcerous impetigo rodens approaches in many respects that of the syphilitic ulcer, that is to say, the ulcer is more or less scooped out, its edges elevated, eliptical, and not rounded as in the cancroid. Third. In the cancroid the secretion resembles the fetid sanies of cancer, while in the ulcerous impetigo rodens it partakes of the character of pus' and sanies. It is not so much that serous secretion which passes through all the dress- ings, as in cancer, and has a penetrating odor, as it is a mixture of pus of good character with a serous secre- tion which has no very marked odor. Fourth. In impetigo rodens we are very liable to have a flow of blood upon the slightest touch, the least rubbing; a disposition much less prominent in cancroid. Fifth. Without giving as a distinctive characteristic, the difference in location of the one and the other affection, yet there is in this respect a shade of difference that *y be established. Both are seated most often upon the face, but while the caneroid may attack all points of the face, and particularly the lips, under the form of * *gorgement, most often non-ulcerous at the outset, * embracing the whole thickness of the tissues; the * impetigo rodens is seated almost constantly at * of the corners of the eyes or on the side of the nose. Let it not be thought to be limited to small super- ficial ulcerations; its ulcers are sometimes 4 or 5 centi- metres in diameter, they are deep, of unhealthy appear- ance, with elevated indurated edges, bleeding, their sur- face generally longer than it is broad, sinuous, turn- ing from right to left, sometimes multiple and connected by ulcerated linear tracts, or separated by bands of healthy skin. To the touch, itsedges are hard and present a certain resemblance to cancroid. Sixth. It is a remark- able thing that the impetiginous disease originates in very circumscribed points, these points requiring years to attain diameters of from 2 to 3 centimetres. The surrounding skin is supple and perfectly healthy. There is no acute lancinating pain as in cancroid, simply tingling, like the sensation of a fly on the parts. These last characteristics are the most important, viz., the time that the disease requires to attain its small size, and the absence of shooting pains, in place of which there is tingliag in all the parts. While a pustular button with a sanious top resting upon an indurated base is the commencement of the trouble in cancroid, quickly transformed into an ulcer with elevated edges; wlcerous impetigo rodens shows itself by a circum- scribed point or linear ulceration, very slowly progress- ing, affecting principally, one of the angles of the eye, and the external angle by preference. Often, indeed, it is followed and that at a distance somewhat removed by a new small ulcer. The one and the other require years to attain any special size. This multiplicity of the points of departure, is a strong indication of impetigo rodens, for in the caneroid the outset and progress of the disease is almost constantly from a single point. An ulcer of impetigo rodens will require 3, 4, or 6 years to reach a length of from 10 to 25 millimetres; whlie in the course of a single year the cancroid will reach in extent and depth 3 or 4 centimetres, more or less. Seventh. In the cancroid the induration of the tissues shows itself with the disease, while indulation of a certain part of the sore will not appear in impetigo rodens till many years after its first manifestation. Such are the distinctive characteristics that I believe can be established between these two diseases. There are in them both peculiarities that we cannot point out before noticing the characters of ordinary impetigo. The name, impetigo, has been always given to a superficial pustular eruption, made up of psydracious pustules; that is to say, of pustules exceedingly thin, running together, drying rapidly and forming a crust, more or less yellow, sometimes canary-yellow, as in ordinary impetigo occurring in young persons. This then is the first char- acteristic to be noticed in the disease which occupies our attention. The second is indicated by the word rodens, “gnawing,” which signifies a disease which destroys more or less tissue. Simple impetigo is an affec- tion of the skin wholly superficial, which never leaves its traces other than in those exceptional cases where parents have left for years upon the head and forehead of the child an indolent dry crust without making any 76 [FEB. 17, 1872. T THE IFE C T , IL N T C - effort to remove it, in which cases the pressure of the crust upon the tissue ends in leaving a mark which is not effaced for a long time. But this is a print rather than a cicatria. In impetigo rodens the fall of the crust leaves always its indelible trace. petigo rodens which is always of more or less long stand- ing, the characters of the pustule of impetigo have dis- appeared, but any slight artificial irritation, as by a caustic application to one of the points of the surface, will suffice to bring out again the characteristics of the impetiginous secretion. The practitioner may by this means establish a diagnosis, differential and precise. [To be Continued.] ---—-mº-e-ºº--— SCIENTIFIC NOTES. •º. Vaso-MI6tor and Trophic Néuroses. IBY DR. A. EULENBURG (Berlin). A Lecture delivered before the Hufeland Society, Oct. 27, 71. (From the Berlin Klin. Wochertschr, Jan: 8, '72); GENTLEMEN : Allow me to make a little excursion into a region of nerve pathology that is perhaps of all the least circum- scribed in its range—the region of the vaso-motor and trophic neuroses. I can not of course conceive that I may be able to treat this subject here in any manner exhaustively, but I may attempt to bring out a few leading points that may serve as guides to further ex- planations in a territory so obscure. As chief considera- tion upon which I would like to dwell are the differ- entiations and analogies between vaso-motor and trophic neuroses, or, in a word, between angio-neuroses and tropho-neuroses. As is well known, the latter com- menced to play an important role in nerve pathology at an earlier period. I may only remind you that Rom- berg and Bergson designated progressive, one sided facial atrophy as a tropho-neurosis and Baerensprung derived herpes zoster from an affection of the trophic fibres aris- ing from the ganglia of the spinal cord. These views were adopted at a time, however, when the existence of trophic nerves was by no means demonstrated, but was considered only as a theoretical postulate. When some ten years ago these investigations on the vaso-motors received their new impulse from the labors of v. Bezold, Goltz, Ludwig, Thirg and others, there was the tendency to refer all pathological alterations of nervous origin not only in the circulation, but also in temperature, secre- tion and nutrition of individual parts of the body to a mor- bid action of the vaso-motor nerves. These efforts, in which I myself was extensively engaged, had, without doubt, much to justify them ; but they were carried too far, as actions were ascribed to the vaso-motor system In the ulcerous im- which we now know to be only effected with the con- currence of certain other factors of the nervous system. And when the term “trophic nerves” is applied to these factors, still is the conception an imperfect one. The general idea, however, is this; these nerves have to do not only with the nutrition of the parts in the narrower Sense of the term, but also with the regulation of the Secretory and absorptive processes of the economy. Later experimental investigations have demonstrated that the accomplishment of these processes is effected by nerves which may not be regarded as of vaso-motor function as these processes are continued even after destruction of the circulation. I may mention, for ex- ample, in regard to Secretion, the experiments of Ludwig and v. Wittich on the parotid gland. Ludwig has shown that the secretion of saliva is independent of blood pres- sure; when the nerves of the salivary glands are irri- tated, the pressure of the secreted saliva is greater than the pressure in the carotid artery; so likewise the tem- perature of the saliva may be higher than that of the blood. Wittich has proven that excitation of the cervi- cal sympathetic acts upon glandular Secretion in the same way even after arterial anaemia has been induced in the gland by ligation of the carotid artery. In ab- sorption Goltz has recently developed some facts by his very interesting experiments. If water or a Salt solution were injected into the lymph vessels of frogs after all the circulation had been arrested by ligation of the heart, while the brain and cord were left intact, the fluid injected was nevertheless almost totally absorbed —on the other hand, if the brain and cord were de- stroyed absorption was not affected. I may mention incidentally, also, other experiments of Goltz which dem- onstrate that the shiny, moist and wrinkled condition of the skin of the frog is maintained so long as the cen- tral nervous system is preserved intact; that, further, after destruction of the nervous system and one-sided section of the nerves distributed to the skin, the skin in the side of Section becomes more transparent because of the death of its pigment cells. Later histological develop- ments coincide with these results of experimentation. I remind you especially of the path-breaking discoveries of Pflüger, as to the different terminations of nerves in the gland cells of the salivary glands as well as of the liver and pancreas. These are nerves which Pflüger has designated nerves of Secretion. Pathological disturb- ances of these nerves may be termed appropriately neuroses Sui generis, glandular or Secretory neuroses. Still later discoveries have taught us further that not only the gland cells, but also cells of other tissues espec- ially of the epithelial contain terminations of nerve fi res. ' hey have been demonstrated in the posterior epithelial layer of the cornea, and in the nucleoli of their cell elements (Lipmann), further in the epithelium of the frog skin, in the connective tissue of the tail of the tad-pole (Hensen, Eberth). All these, so to speak, cellular nerves are probably of essential influence on the vitality of their cells as well as on the transforma- FEB. 17, 1872.] T IEI IET: C T , T INT I C. 77 tions of constructive and retrograde metamorphosis: and through this influence we are possessed of a surpris- ing confirmation of many pathological conditions, as, for instance, the corneal affections in the neuroparalytic affections consequent upon lesions of the trigeminal Iner Ve. It is not at all improbable that we may finally succeed, by the method of developing terminal nerve fibres, which is so essentially perfected in modern times, in demonstrating the connections of nerve fibres with other gland cells and with the cellular elements also of other tissues and thus may enlarge the histological field of the secretory and in a narrower sense the trophic neuroses. Experiment and pathology have, in a sense, anticipated these discoveries in histology, since they bave demonstrated that alterations in the nutrition o. the most different tissues—epidermoid, subcutaneous, muscular, osseous, articular, lymphatic—ensue in cont sequence of artificial or accidental injuries of nerves. Without mentioning the numerous experiments per formed in proof, I will only call to mind the phenom- ena following gunshot injuries or other traumata causing partial or total destruction of mixed nerve trunks. Our late war has furnished abundant material for this purpose and I have myself observed the most exquisite examples in proof. I am treating at present, for instan :e, a case of destruction of the ulnar nerve above the wrist: in this case the skin in the whole ulnar region of the finger is remarkably cool and pale as well as smooth, dry, and totally void of Secretion; the last phalanges are narrow and pointed, the nails are deformed and hypertrophic. The muscular tissue of the little finger is gone; there is constant tendency to panarities (felon) and ulceration. In other cases, as Fischer has lately exhibited, oedema and erysipelatous reddening (the shiny fingers and toes of Paget), further, anomalies in the growth of the hair, exanthemata, anchylotic joint inflammations, contractions, hyperplasia, and later, con- centric atrophy of the bones have all been observed after injury of the nerves of the extremities. To refer all these alterations exclusively to injury of the vaso- motor nerve fibres would be a labor of the greatest diffi- culty; for we know that elevation of temperature, red- dening and increase of secretion occur after division of the vaso-motors—effects which, after injuries of mixed nerve trunks, either do not present at all or only transi- torily, and, as a rule, soon to manifest opposite appear- ances. There must be, therefore, some further condition which compensates or more than compensates for the injury of the vaso-motors, and this, in the injury of mix- ed nerve trunks, is the concomitant injury of the secretory, and in a narrower sense, the trophic nerve fibres. When We, thus, in future, disassociate the disturbances of the vaso-motor, secretory and trophic nerve systems more dis- tinctly than ever before, we dissipate, to great extent, the cloud of obscurities and seeming contradictions which has hitherto and in high degree rendered difficult the comprehension of numerous neuropathological con- ditions. These difficulties depend mainly upon the fact that all disturbances of secretion and nutrition of neu- rotic origin were referred to disease of the vaso-motor fibres, either to their excitation or paralysis. As exam- ples, I may cite the disturbances of nutrition incident to many cases of trigeminal neuralgia, as ophthalmiae, herpetic and other exanthemata, atrophy and decolori- zation of the ciliae, superciliae and hairs of the head, atrophy of the skin and of the other soft or even bony parts of the face. These manifestations are referable neither to a contraction nor a reflex paralytic relaxation of the bloodvessels, since the symptoms proper to these conditions may be totally absent. On the other hand, in other cases of trigeminal neuralgia and still more in hemicrania we observe these vaSO-motor symptoms prominent while trophic disturbances of the kind just portrayed are absent. Meissner thus maintains and with great probability that ophthalmia neuroparalytica after injuries to the trigeminus does not depend upon a lesion of the vaso-motor, but of the specific trophic fibres accompanying the trigeminus beneath the Casserian ganglion. The one-sided progressive atrophy of the face occurring occasionally as an isolated disease it is cer- tainly unreasonable to refer to vaSO-motor cramp of a years duration; as little, too, are evidences of a relaxa- tion of vessels present, so that we must necessarily recur here to disturbances in the trophic symptom as Samuel has long ago justly maintained. It is worthy of men- tion, too, that hypertrophy of one side of the face may occur in connection with injuries of nerves; Sterling has already communicated an interesting case of this kind. This coincides perfectly with the experiments of Mantegazza who has observed hypertrophy of the con- nective tissue, of the periosteum, the bones, lymph glands, etc., in animals after section of the nerves. Morbus Basedowii, also, belongs in all probability to the trophic neuroses. Just here irreconcilable con- tradictions present on the old theory. The acceler- ated pulse was derived from an excitation of the cervi- cal sympathetic while the struma and exophthalmus were referred to a paralysis of the vaSO-motors of the cervical sympathetic (or their spinal centres) supplying the different vessels concerned. It is, probably, much nearer the truth to believe that an affection of the spe- cific trophic nerves is the cause of the glandular hyper- plasia and perhaps also of the remarkable increase in the retro-bulbar adipose tissue of the eye. Permit me now, in brief, to present another side of this subject, viz., the new and valuable points that may often be obtained in more accurate local diagnosis by this separation of vaso-motor and trophic symptoms. In lesions of peripheric mixed nerve trunks, in the rule, trophic and vaso-motor fibres are simultaneously affected. Våso-motor and trophic symptoms, therefore will mani- fest coincidently or in succession, as has been stated to occur after traumatic injuries to mixed nerve trunks. Nearer the centre, however, the vaso-motor and trophic tracts separate from each other as distinctly as do motor 78 [FEB. 17, 1872. T IEEE THE C T , T N T C . and sensitive fibres. It may be regarded as pretty well demonstrated that as there are separate centres for innervation of the heart, and bloodvessel tonicity so there are also separate centres for the regulation of ani- mal heat and of nutritive interchanges, but particularly for the nutrition of muscle. Concerning this tissue, especially, these centres for the voluntary muscles of the trunk and extremities are plainly situated in the anterior columns of the spinal cord and their fibres pass out into the anterior lateral columns of the cord and the anterior roots. Pathological conditions speak with decision in favor of this view. Confirmation is much more fre- quently found in recent times with the frequent and accurate microscopic examinations of the hardened cord than formerly under the more imperfect means of inves- tigation. Thus it is more and more frequently found to be true that the neuroses marked by extensive mus- cular atrophy, especially the so-called progressive muscu- lar atrophy is a aconsequence of a chronic myelitis or a simple degenerative atrophy of the anterior column of ganglion cells, and of the anterior column and root fibres of the spinal cord. I may remind you here of the older descriptions of Valentiner, Gull, Clarke, Luys and the later of Grimm, Bamberger, Joffroy, Rosenthal and others. That interesting neurosis described by Leyden, the so- called paralysis glosso-pharyngolabialis belongs here also. This is likewise attended with atrophy of the muscles concerned and is often associate with progressive mus- cular atrophy, being either the beginning of this affec- tion or complicating its close. Leyden found chronic myelitis constantly in this disease, particularly in the upper cervical region of the cord with degeneration of the anterior lateral columns and fatty atrophy of the anterior roots. In a third, only lately frequently ob- served neurosis, progressive muscular hypertrophy or lipomatosis musculorum luxurians where the volume of the muscle attacked seems to be increased by interstitial increase of fat while the muscular tissue itself disappears, I have already upon a former occasion felt myself con- strained to accept the view of a special origin of the dis- ease. I based this especially upon clinical grounds, particularly on the coincidence of this process, as I my- self first observed, with progressive atrophy in other muscle regions. This view, too, has been confirmed in the meantime by Barth, who demonstrated in a case, points of degeneration in the anterior horns and anterior lateral columns of the spinal cord. Finally there is to be arrayed here also a fourth affection, namely, the so- called essential or spinal paralysis of childhood. It is well known that in this condition there is by no means a definite paralysis, but an often rapid atrophy of muscles sometimes even of an entire extremity. It is then much more proper to designate the effection an essential atrophy or at least with Duchenne, a paralysie atrophique. The presumption was a safe one, therefore, to locate this affection as a primary lesion of the above mentioned regions of the spinal cord and to explain by its grade the variable extension of the peripheric muscular disease. But till now, there were lacking any more definite and exact results in confirmation. These deficiencies, how- ever, have been lately been filled by several French pathologists, Charcot, Parrot, Joffroy and Vulpian. They all found—and they were unanimous in descrip- tion—degenerative changes in the anterior horns and the anterior lateral columns as well as in the anterior roots of the spinal cord; differing only in grade accord- ing to the duration of the disease process, corresponding in all cases to the extent of peripheric muscular affec- tion. Recklinghausen, also (according to Rinecker), has observed in these cases atrophy of the anterior ganglion cells, of the anterior columns and of the anterior por- tions of the lateral columns of the cord. We may there- fore consider the proposition as established, that mus- cular atrophy may be ascribed to disease of the anterior column of ganglion cells including the anterior column and root fibres of the spinal cord. Thus also the occur- rence of diffuse muscular atrophy in connection with other spinal symptoms—paraplegia or spinal ataxia, for instance—signifies and is to be regarded usually as an extension of the original disease process to the gray sub- stance ef the anterior columns and the anterior ganglion cells. You observe thus, gentlemen, that clinical observa- tion and pathological anatomy must advance hand in hand with physiological experimentation to render at all possible any accurate comprehension of the multi- form disease processes of the nervous system. You see also how wide a field in this direction opens out before us. In the department of pathology it is not so much facts that are wanting as the proper interpretation of these facts, their reconciliation with established physio- logical data. This deficiency is easily understood when we remember that the physiology of the nervous system is still only in progress of revelation. The results of these investigations are of highest consequence in therapy, a department which already counts so many and so important acquisitions and yet has fallen into So many deplorable errors; errors rooted in the main in unphysiological comprehensions of the applications of valuable remedies. I refrain from entering this subject further although my theme admits a most instructive corollary. May we never forget that the pathology of the nervous system owes its brilliant inception and its entire development to the fact that its indomitable founder has bound it indissolubly with the physiology or (as J. Müller puts it) with the physics of the nerves | THE CHEMISTRY of HAIL–Prof. Kengott, of Zurich, states that a hail-storm lasting five minutes occurred at eleven o’clock in the morning of August 20, 1871, the stones from which were found to possess a salty taste. Some of them weighed twelve grains. They were found to consist essentially of true salt, such as oc- curs in Northern Africa on the surface of the plains, mainly in hexahedric crystals or their fragments, of a white color, with partly sharp and partly rounded FEB. 17, 1872.] T H H C T.I.N.T. C. 79 grains and edges. None of the crystals were entirely perfect, but appeared as if they had been roughly de- veloped on some surface. They had probably been taken up and brought over the Mediterranean from Some part of Africa, just as sand is occasionally trans- ported hence to the European continent and the Canaries by means of hurricanes. A still more remark- able phenomenon has been recently recorded by Prof. Eversmann, of Kasan—namely, the occurrence of Hail- stones, each containing a small crystal of sulphuret of iron. These crystals were probably weathered from Some rocks in large quantity, and were then taken up from the surface of the ground by a storm, and when carried into the hail-forming clouds served as a nucleus for the formation of hail-stones.—Nature, Jan. 11, ’72. THE FECUNDITY OF GERMS.—For we know that these low forms of organization are especially distin- guished by their power of rapid multiplication. Each individual plant of Reticularia marima,” a species of fungoid vegetable, produces no less than ten million of spores; and, according to Dr. Carpenter, a large kind of fungus, the Bovista giganteum, has been known to grow so rapidly that its cells must have been produced at the rate of four thousand millions per hour. Many of the infusoria also multiply themselves by division, and in this way increase rapidly in numbers in any in- fusion which is suitable for their growth. Prof. Bastiani has seen under the microscope a bacterium, of moder- ate size, “divide into two, and each of these into two others, somewhat smaller, in the course of fifteen min- utes.” But if such an organism were only to divide into two once in every fifteen minutes, and if this process were to go on for six hours, we shonld have at the end of that time over sixteen millions of bacteria, produced from a single individual. There is no diffi- culty, therefore, in accounting for the abundance in which the infusoria may appear in a solution, after a few germs have once been introduced from the atmos- phere.—Dalton–N. Y. Med. Journ., Feb., 72. —sº-G-seºn--- MEDICAL NEWS. CHARLES LEVER ON THE MEDICAL PROFESSION.— We print elsewhere a letter bearing the signature of Charles Lever, which appeared in the Pall Mall Gazette of Tuesday last and which bears a tribute, of which we may be justly proud, to the high moral and intellectual qualities of the members of the medical profession: qualities in no small degree due to the exercise of the calling in which the medical life is spent. Mr. Lever justly points out that the doctor is familiar at once with some of the deepest problems of science, and of the Practical working of the truths whence these problems T--— *9ted in Longet, Traité de Physiologie, vol. ii., part iii., p. 13 tºeneral and Comparitive Physiology, p. 95. torigin of the Lowest Organisms, p. 6. London, 1871. proceed. He shows also how the familiarity with the profession with all classes raises it above the prejudices of any, and renders it peculiarly fit to guage the state and tendencies of the national mind. We can not but warmly welcome an advocate so able; who says for our calling so much that modesty prevents us saying for ourselves, but which it would be mock modesty not to accept when said by another. It is not the least among the triumphs of medicine that it has numbered amongst its panegyrists the greatest names in literature. The eulogy sung by Homer has been reechoed from his time to ours; and Mr. Lever does but strike a chord that has already responded to the master touch of Thackeray and of Dickens.—London Lancet, Jan. 20, '72. GERMAN PROVISIONS FOR THE STUDY OF SCIENCE.- Although a stranger visiting Germany is in admiration at the number of laboratories and institutes that he sees everywhere, the Germans themselves are in the habit of grumbling that they have not enough; and just recently, provision has been made, in the budgets adopted by the legislature, for some consider- able extensions. Munich is to have a new pathological institute, separate from the hospital, at a cost of about £16,000, and £4,000, is to be spent on extending the physiological laboratory. Erlangen, also, another Bava- rian University, is to have a new pathological institute. The University of Berlin has had the sum of half a million thalers (about £75,000) voted to it for similar purposes. A fourth part of this sum is to be expended on a new physiological laboratory; and it is expected that a laboratory for physics will be built ajoining it. The pathological institute, already very complete, will be enlarged, at the cost of about £3,000, the extension being mostly in the department for pathological chem- istry, to which a suite of five rooms will be added, pro- viding accommodation for physiological and physical apparatus. It may be useful to mention that there is a description of the pathological institute at Göttingen, accompanied by plans written by Professor Krause, the director of the institute. In about one half of the German Universities there is an institute for path- ology separate Some little distance from the hospital; and this arrangement is found to be so convenient, that it will no doubt soon be universal. AN ERROR OF THE EMPIRE-The new and magnifi- cent Hotel Dieu whose construction has already cost many millions of francs and which would require in ad- dition for its completion, at least five millions, and for the roofing and walls two millions, has been utterly condemned by a commission of the hospital surgeons and physicians of Paris, after a thorough examination. After hearing the report of some of the most competent authorities, the Society of Hospital physicians and surgeons unanimously resolved that the Hotel Dieu, by its construction does not fulfill the conditions required by a hospital in the actual state of science and hygiene. Drs. Hérard and Hardy alone, while admitting the con- 80 [FEB. 17, 1872. T TEI IET: C T I I INTT C. struction of the hospital to be detestable would have been willing that the eight hundred beds should be re- duced to four hundred, and the building utilized for diseases of the skin, eyes, etc., keeping away really sick people—a proposition which was emphatically negatived. As a hospital this costly error of the empire would be more murderous than a great battle. It may be utilized as a Hotel de Ville in lieu of the building destroyed by the communists.-Brit. Med. Journ., Jan. 20, '72. “THE INVENTOR AND REVEALER OE ANAESTHETIC INHALATION.”—The committee of citizens of Boston chosen to raise a Morton Testimonial Fund, claim that no one, either in or out of the profession, up to the final experiment with ether at the Massachusetts Gen- eral Hospital in 1846, by William T. G. Morton had ever dared, in public or private, to saturate a man with ether, with the intention of producing insensibility to pain, and still less with the idea of urging a surgeon to perform a long and painful operation upon the uncon- scious patient. “The Historical Memoranda” states that “more than a year after the first operations were performed, the late Sir James Y. Simpson sent his pamphlet on chloroform to Dr. Morton, and after speak- ing of ether, and of its use as an anaesthetic,” he adds, —“Of course, the great thought is that of producing in- sensibility to pain; and for that the world is, I think, indebted to you.” . The Committee to obtain a proper testimonial for the family of the late Dr. Wm. T. G. Morton is composed of the following gentlemen: Drs. Chas. G. Putnam, Henry I. Bowditch, Geo. Hayward, R. M. Hodges, Luther Parks, Sam’l Kneeland, John C. Warren, and Fracis Minot, of Boston. The names of the following physicians of New York and Philadelphia have been added, with the consent of the various parties: Drs. E. R. Peaslee and Willard Parker, of New York, and Drs. S. D. Gross, J. M. Da Costa, and S. Weir Mitchell, of Philadelphia.-N. Y. Med. Rec., Feb. 1, ’72. THE WURzBURG CLINIC.—For the Professorship vacated by Bamberger, called to Vienna, the names of Prof. Biermer (Zurich), Prof. Gerhardt (Jena), and Prof. Leyden (Königsberg) are proposed. The Prussian journals lament the possibility of the loss of Leyden from one of their universities. A NEW FIELD FOR HOPPE SEYLER.—Hoppe Seyler, hitherto in Tübingen, has received a call to the chair of medical chemistry in the newly established university of Strasbourg. DEATH OF JAGER.—The renowned ophthalmologist Friedrich Jäger, Ritter von Jaxtthal, died in Vienna, Dec. 26, ’71, in the 88th year of his age. His no less distinguished son Prof. Edward Jäger continues in pos- ition. * HoNors To DR. CoRMACK.—Dr. John Rose Cormack, the correspondent of the British Medical Journal during the Franco-Prussian War, and formerly its editºr, is about to receive the honor of Knighthood for his devo- tion to the cause of the wounded during the sieges. His Services have already secured for him the thanks of the French and English Governments, and the Cross of the Legion of Honor. CHLOROFORM AN INELIGIBLE AGENT FOR ROBBERS. —Dr. Stephen Rogers, of New York, in a reprint on “Can Chloroform be used to facilitate Robbery 7” re- cords some facts which prove it to be an ineligible agent for the use of robbers. 1st. As to its use to promote the greater security from the disturbance of the sleeper, even were that practicable, the very time that would be consumed in the gradual and cautious administration of the vapor—the only possible theoretical manner of accomplishing it—would so increase the danger of detec- tion that few thieves would think of employing it. 2d. During the course of the administration of chloroform, whatever manner may be adopted, the patient or sub- ject, as a rule, becomes excited, often very violent and turbulent, with an irrepressible propensity to sing or shout, which is often so loud as to alarm the inmates of the whole house. He is in a state of wild chloroformic intoxication. The exceptions to this rule are so few that no prudent thief would think of running the risk of not meeting one of those exceptions; 3d. Supposing the two preceding obstacles overcome, and the victim thoroughly quieted into a narcotic sleep, a third and very frequent complication arises: he begins to vomit, and, while he does not generally make much noise about it, still he may, and he always requires attention lest fatal strangulation occur. The knowledge, among the criminal classes, that the abandonment of their vic- tim with a towel still over his face, to the liabilities of vomiting and strangulation, would often add the crime of murder to that of robbery, would have great effect in deterring them from the further employment of it.—Med. Rec., Feb. 1, ’72. —sº- e-Gº--— correspondence. Diagnosis of Syphilis by the Microscopic Examination of the Blood. VIENNA, January 12, 1872. MESSRS, EDITORS,--I have just returned from a meet- ing of the “Gesellschaft der Aerzte,” at which was announced a discovery of the most stupendous impor- tance. I am eager to be the first to herald to the new World, through your pages, the greatest success—I may venture to say—as yet achived by the microscope, to wit, the certain diagnosis of syphilis, I will give briefly, from memory, the course of procedure which led to this grand result, having first recorded the name of the propounder of the new theory as Dr. Lostorfer. Wishing to make a series of examinations of blood from FEB. 17, 1872.] syphilitic patients, Dr. L. applied to Prof. Zeissl, in August last, who at once placed his wards at the service of the investigator. The manner of conducting the re- Searches consisted in taking a drop of blood, placing it immediately between a slide and covering glass, then Setting the specimen under cover. A large number of slides were thus prepared, and daily examined micro- Scopically with a No. 10 immersion lens, Hartnack. The first two days nothing abnormal presented itself; but, on the third, minute shining bodies were discerned, which grew from day to day, until they attained the size of red blood-corpuscles. The shape was, in most instances, round, but modifications of that form were here and there noticed; they were all, however, provi- ded with tapering processes or “sprouts” The number of these corpuscles to be seen at one time within the field of the microscope was variable, amounting in only one specimen to fifty. A month later these objects were still visible. A solution of sugar, as well as several other solutions, caused them to shrivel up, become, as it were, folded upon themselves, lose their shining aspect, and cease to grow. Cold was also found to effect their development, inasmuch as a temperature below 10° Reaumur (54°Fah.) put a stop to all growth To prove the connection between these bodies and syphilis very many experiments were made with healthy and diseased blood, and the diagnosis confirmed beyond the possibility of doubt. Blood was then daily examined while the patients were undergoing treatment with mercury (einreibun- gen), and, after a certain time (in one case twenty-five days), during which the number of corpuscles was stead- ily decreasing, they had wholly vanished from the field. After these experiments, Dr. Lostorfer submitted him- self to Prof. Stricker and later to Prof. Hebra to have his power of diagnosticating syphilis, by the microscopic appearances of the blood, put to the test. On various occasions he received from them numbered slides with blood of syphilitic and non-syphilitic individuals. To their astonishment, he unerringly selected from the preparations those where the blood was tainted with syphilis, with the exception that on certain slides the blood was pronounced to be in a condition allowing of no conclusion being arrived at. The discoverer gives the name of syphilitic corpuscles to these bodies, which, he said, must originate in one or two ways—either from germs always present in the blood, but stimulated to #." by the syphilitic virus alone, or from such introduced bodily into the blood at the time of infection. In conclusion, he read the records of a number of cases with his microscopic observations of the blood from day to day. As Dr. Lostorfer ceased Speaking, a burst of genuine enthusiasm escaped from the assembled physicians, while Prof. Sºoda rose to greet the hero of the evening, as the proclaimer of what was destined to prove one of the most important discov- °ries of the age. He regretted that it was not customary TIH. H. cI.TINT C. 81 in Austria to give medals or other rewards of merit in such cases, stating that, had this statement been made in Paris, he would have been crowned, as he deserved. Prof. Stricker detailed the precautions taken to avoid error or deception in each of the trials to which Dr. L. was subjected. The latter's selection of diseased blood was always correct, and decided, except in the few ruined specimens. To ensure the purity of the healthy blood, he had taken his own and that of his servant. After a while Dr. L. distinguished between these two, inasmuch as the professor's was thicker and “dirtier.” Prof. Hebra confirmed all that had gone before, and said he had been so much struck with the discovery, that Prof. Stricker’s blood “contained more filth (schweinerei) than that of any other living man,” that he had instituted researches for similar peculiarities among his patients, but, thus far, without result. No words are needed to show the immense field for research, thus suddenly thrown open to investigators, nor can the practical results likly to proceed from this study be over-estimated. Microscopes all over the world will now be turned toward these new constellations, and their every freak recorded. Theories of unity and duality will soon cease to vex the earnest student and practitioner, and half the skill and learning of dermatologists is made of no value by this simple and certain indication of the presence of the syphilitic virus. The testimony of two such renowned and incredulous men as Professors Stricker and Hebra is a convincing proof that these corpuscles are not bub- bles to be pricked by the next impertinent microscopist. I trust I have not omitted nor misstated any of the main points of Dr. Lostorfer's paper, but if so, will send you in expiation of my offence a copy of his article, as Soon as printed. I am yours, &c., James R. Chadwick, M. D. —Bost. Med. Journ., Feb. 8, '72. —-º-º-º- ICOOIKS AND PAMIPIHILETS RECEIVERD. DALTON'S TREATISE ON HUMAN PHYSIOLOGY- Fifth Edition Revised and Enlarged—Philadelphia, Henry C. Lea, 1871—For sale by Robert Clarke. The best text book on Physiology extant in any land or language. HAND BOOK OF SIKIN DISEASES BY DR. ISIDOR NEU- MANN–Translated from the Second German Ed. by Lucias D. Bulkley, A. M. M. D. New York, D. Apple- ton & Co., I872. For sale by Geo. E. Stevens & Co. To be Reviewed. - PULMONARY CONSUMPTION, ITs NATURE, VARIE- TIES AND TTEATMENT by C. J. B. Williams, M. D. F. R. S., and Chas. T. Williams, A. M. M. D. Philadel- phia, Henry C. Lea, 1872. For ſale by Robert Clarke, $300. To be Reviewed, 82 [FEB. 17, 1872. TIEEE CI.I.INI c. WoRKS OF SIR. J. Y. SIMPSON.—Anaesthesia, Hospit- alism, Hermaphroditism. New York, D. Appleton & Co., 1872. For sale by Robert Clarke, $500. To be Reviewed. ESSENTIALs of THE PRINCIPLES AND PRACTICE OF MEDICINE by Henry Hartshorne, A. M. M. D. Phila., H. C. Lea, 1871—Third Ed., thoroughly revised. For sale by Robert Clarke & Co., $238. The best “crammer” out. Like all short cuts to knowledge, however, abrupt and deficient. THE AMERICAN PRACTITIONER–2 Vols., 1871. Superbly bound volumes of a first class journal. FIRST SPECIAL REPORT OF THE CHICAGO RELIEF AND AID SOCIETY.—Chicago, 1871—A thorough ex- posè of the world’s charity to our distressed sister city. TWELFTH ANNUAL REPORT OF LONGVIEW ASYLUM for the year 1871. THE INFLUENCE OF SPECULATIVE BELIEFS IN MED- CINE by Z. C. McElroy, M. D. Reprinted from the Cincinnati Lancet and Observer, Jan., 1872. Trash. THE HEALTH AND WEALTH OF THE CITY OF WHEELING by Jas. E. Reeves, M. D., Health Officer, 1871. A model report. —º-e—sº- (CJLHN}{{`AH, MIFMIORAN IDA. Phrenic Neuralgia. BY DR, MICHEL PETER (Paris). With this name is offered to neuropathology a hither- to unknown, at least undescribed form of neuralgia which is by no means of seldom occurrence, and which owes its symtomatology to several well known forms of disease, as angina pectoris, pleuritis diaphragmatica, pericarditis and hepatitis. It has been hitherto unrecognized because the mixed character of the phrenic has not until of late been recognized. Its characteristic symptoms are as follows: 1. Jaliopathic pains, most severe in the lower part of the chest and in the shoulder, less in the neck and nucha. These pains are increased by pressure. 2. Points of tenderness, corresponding to the course of the phrenic nerve, thus, at the anterior attachment of the diaphragm from the 7th-10th, particularly at the 9th rib ; at its posterior attachment, particularly at the angle of the last rib, further, at the trunk of the nerve, in front of the scalenus anticus, in the lateral region of the thorax in the 2nd and 3rd intercostal space, especially at the junction of the 3rd rib with its cartilage, some- times a little lower. These last points correspond to the . connections of the phrenic with the cardiac plexus. 3. Irradiating pains due to the connections of the phrenic with the nerves affected. In case of the cer- vical plexus, these are experienced inside the middle of the clavicle, and on the sides of the neck up to the lower jaw; in case of the brachial plexus, pains in the shoulder, inner surface of the arm, elbow and little finger. - - 4. Pains at the spinous processes of the 2nd-4th cervical vertebræ particularly at the 3rd and 4th. 5. Functional disturbances of respiration, mastication, deglutition and motion of the left arm. - Respiration is labored, imperfect and painful as are all acts in which the diaphragm participates—it becomes still more imperfect, even checked altogether by pres- sure on the nerves of the neck which sometimes causes coughing. . The impairment of motion of the arm depends partly on the pains in the shoulder and partly on paresis. The left arm suffers in affections of the heart, pericar- dium and spleen, the right in affections of the liver; affections of the diaphragm affect now one arm, now the other, again both. - Differential diagnosis between phrenic and intercostal neuralgia is easy. • *. - Rheumatism of the diaphragm cannot be differentiated from this affection. The one-sidedness of neuralgia may be a point of value. Diaphragmatic pleurisy is attended with fever ; its symptoms are much more in- tense. This depends, partly, however, upon the con- comitant neuralgia. The same is the case in heart affections; the pain in the shoulder will here excite suspicion. Diaphragmatic peritonitis and hepatitis have their own specific symptoms in differentiation. Angina pectoris has the radiating pains in common with the affection of the text but the anxiety and local cardiac symptoms allow a distinction. Gastralgia which might confuse diagnosis by its spontaneous pains does not possess the points of tenderness described. Intercostal neuralgia, finally, has also its specific character and is usually seated in the middle intercostal region. Phrenic neuralgia occurs Sometimes isolated, some- times intercurrent with other affections, especially hysteria and epilepsy, or with angina pectoris with or without heart disease or with Morbus Basedorwii, with |spleen affections, particularly in consequence of mi- asm or finally with affections of the liver. Prognosis, hence, varies according to these conditions. In simple neuralgia, it is favorable. Its treatment is that for neuralgia in general, wet cups, vesicants, morphia hypodermically, or simple sinapisms with anodyne applications. When the dis- ease is only a symptom, therapy must be directed to its C3, UISC, [Details of 16 cases follow].-Arch. Gen., 6 Str. avii. 303—Schmidt’s Jahrbücher, Jan., '72. " FEB. 17, 1872.] INTESTINAL OBSTRUCTION FROM ACCUMULATION OF FAECES CURED BY THE INTERNAL AND ExTERNAL USE OF ICE.-M. Prunac reports (L’Abeille Médicale, December 25; from Le Gazette des Hôpitauw) a case in which urgent symptoms of intestinal obstruction, de- pendent upon this cause, yielded to the application of ice to the abdomen, and to injections of ice-water every quarter of an hour, after having resisted the more usual methods of treatment. EXTRACT OF MEAT.-Some of the recent experiments on the nutritive value of the Extractum carnis do not give a high estimate of its physiological importance. Herr G. Bunge, who has been lately investigating this subject, under the direction of Dr. Schmiedeberg, of Dorpat, assigns a lower value (as a nutrient material) to the extract than to coffee, tea, or alcohol.—Archiv fur die gesammte Physiologie, Bd. iv. A CASE OF ACUTE CATARACT.-In the Klin. Monats- blat f Augenheilkinde (1870), Ritter reports a case of double cataract formed in less than seven days attended with no symptoms of irritation on the part of the exter- nal or internal membranes of the eye, with no alteration in the aqueous or vitreous humor. As the patient was a fireman the writer considered the intense heat as the cause of the opacity of the lenses. TREATMENToR PRURITUs VULVE.—Those who have had any experience in the treatment of this troublesome affection will learn with interest that Mr. McGrath states (The Canada Lancet, November, 1871) that he has found the following, applied by means of a soft Sponge after ablution morning and evening, attended with the most satisfactory and speedy result;-Biborate of soda, 3ij; hydrochlorate of morphia, gr. xx; hydro- cyanic acid, 3.j; glycerine, fºj; distilled rose-water, f; viij–Phil. Times, Feb. 1, ’72. HOT BATEIS IN HYDROPS.–These baths 28°-34° R., [89°-97°F.] with after perspiration of two or three hours have their indications and contra-indications. No age excludes them, the previous strength of constitution need not be regarded, except that caution must be ex- ercised in debilitated subjects. They are indicated in diffuse transudations in the subcutaneous tissue if not too extensive, in effusions into the peritoneum, pleura, pericardium, etc. If these dropsies are consequences of mal-nutrition—this is to be remedied. Transudations from depression of the heart's energy disappear under appropriate treatment. Transudations after Scarlatina form an extensive field for hot baths. Relief of transudations caused by pathological pro- Cesses is only possible when these lesions can be relieved. If these cannot be relieved the transudation can only be transitorily affected. Even this, however, is a great || comfort to the patient. Hot baths are contra-indicated in capillary bronchitis, beginning lung cedema, diminished excretion of urine, (in which latter case uraemic convulsions may occur). - T EIIL c1. INTI c. 83 They are indicated in chronic liver and spleen affec- tions as also in chronic heart disease as is demonstrated by cases in illustration. Most decidedly are they contra-indicated when fever is present, or disease of the brain or its membranes, in pericardial effusions of high degree or finally when the general strength is extremely prostrated,—Jahrb. f. Rinderheilk. N. F. 3, 1871—Schmidt’s Jahrb., Jan. 2, '72. —º-gº-ºº--— Indications for the Employment of the Catheter in Old People. M. Guyon, in one of his clinical conferences at the Hôpital Necker, lately remarked that retention of the urine is very common in old men, depending generally on affections of the bladder, or of the neck of the blad- der, or of the prostate. Many cases of supposed vesical paralysis are in reality due to prostatic disease. Reten- tion of urine in old people displays itself by symptoms that are eminently variable. Sometimes these symp- toms are strongly marked: the patients require to micturate frequently, and in doing so experience pain and burning heat which lasts for a long time; there may even be constitutional and febrile symptoms. In other instances, again, the symptoms are by no means prominent, especially in those cases where the bladder is but little contractile; the retention is then only indi- cated by percussion, palpation, and catheterism, the latter alone in many cases being reliable evidence of its presence. But this indication that catheterism should be adopted as an exploratory means is somewhat deli- cate, for the operation is not always inoffensive, and the patient suffering but little, subsequent troubles may be attributed by the patient or by his friends to the injudi- cious interference of the surgeon. If, however, the symptoms be well marked, then there is no room for hesitation, and M. Guyon even goes so far as to say that the catheter should be passed in the case of every old man who evacuates the contents of his bladder im- perfectly. He thinks that it is not necessary that it should enter the organ on the first occasion, since, if only introduced as far as the neck, it habituates the tissues to the contact of instruments, and indicates, in part at least, the seat of the disease. Stoppage of the flow of water is always a serious symptom in old people, and the best advice that can be given to them is to be sounded either with a simple sound or with a catheter, and that frequently. Indeed, if relief be not speedily afforded to such patients, dangerous symptoms soon make their appearance in the form of rigors, purulent urine, and violent reaction. Purely medical treatment is of no service in such cases, and he gives an instance in point. In 1869, in the month of September, M. Guyon had in his wards a man aged 48, who, after having been treated by ordinary remedies and by rest, left the hospital, but returned in January, 1870. He was now suffering from orchitis and 84 [FEB. 17, 1872. T H. H. C. T., IISTIC . distinct enlargement of the prostate; he passed water frequently; the urine was thick, but was voided in suffi- cient quantities to lead to the belief that the bladder was thoroughly emptied. On the 1st of February there was some fever present, and on the catheter being intro- duced about four ounces of urine were drawn off, and on a second occasion about six ounces. He was sounded four times, and was then told to sound himself. No other treatment was adopted. On the 7th the urine was clear yellow, and on the 15th he was able to remain five hours without urinating. Catheterism practiced in his case twice a day caused no return of the epididymitis. In another case, occurring in a dyspeptic subject, all the symptoms of cystitis were present. For a long time M. Guyon hesitated to sound him, and for two months he was treated medicinally without effect. At length he was catheterised, and the urine drawn off. The symptoms immediately diminished in intensity, and from this moment the urine, which had up to that time been troubled and imperfectly discharged, became limpid and even entirely evacuated. A third patient passed blood, and was obliged to remain in the recum- bent position. After careful exploration M. Guyon recognised the existence of retention of urine, and passed a catheter. From this time all the symptions of stone of which the patient complained disappeared. Thus not only stoppage of the flow of water occasions grave accidents, but it stimulates other diseases; it causes alterations of the walls of the bladder, and provokes cystitis. When the bladder is greatly distended, how- ever, it is imprudent to evacuate it completely. The frequency with which catheterism should be repeated is an important question. No absolute rule can be laid down, but it may be performed every five hours; but commonly the instrument should only be passed when there is intense desire to urinate. If, however, he ex- perience but little or no inconvenience, it should be passed at regular intervals. As a rule, the permanent retention of the catheter in the bladder is to be avoided, except perhaps in cases when the desire to pass water is very intense and frequent, or when the introduction of a catheter is very difficult. M. Guyon cites a case where it was worn for two years. It should in general be fixed in position till the bladder is habituated to catheterism. As adjuvants to the above treatment, in- jections may be employed, which may be hot, cold, or medicamented as occasion may require. (Lucas- Championnière's Journal de Médecine, tome xlii., cahier 2). — The London Practitioner, Jan., '72. ANTIDOTE TO CARBOLIC ACID.—Dr. T. Hasemann, from numerous careful experiments, both chemical and medicinal, advocates the use of a strong solution of Saccharate of lime, of course to be taken as soon as possi- ble, as an antidote to carbolic acid.—News and Library, Jan., '72. PHAGADAENA OF THE PENIS TREATED BY OPIUM.– A case under the care of Mr. Pollock, of St. George's Hospital, shows the advantage of this plan of treatment well. The patient was admitted with a phagadaenic ulceration of the glans penis, probably of syphilitic origin. He was ordered fifteen drops of tincture of opium every four hours; but as at the end of two days the patient had not made satisfactory progress, the dose was increased to twenty drops, and was combined with half a drachm of compound spirit of ammonia. At the same time a weak solution of carbolic acid was applied locally on lint. A speedy improvement was now observed, and cicatrisation was almost complete in a fortnight.—The London Practitioner, Jan., 1872. FISTULA FOR CYSTITIS.—Dr. Emmet reports in de- tail the history and treatment of several cases of cystitis in which a vesico-vaginal fistula was made for relief. He says “in making the selection I have intentionally presented some of the cases with which I have had most difficulty, wishing rather to give prominence to the dangers than to mislead.” In all he has operated in some ten or twelve cases, of which the present report embraces four, “I have had but one death follow the operation, the history of which is given in my work on Vesico-vaginal Fistula, p. 237. Case LXXIV—Cystitis resulting from cold, of eighteen years duration, followed by a pelvic abscess, which soon afterwards opened into the bladder and vagina. Fifteen months previ- ous to admission incontinence of urine suddenly took place with partial relief of the cystitis afterward. The vesico-vaginal sinus was enlarged so as to allow of the free escape of urine. Death from uraemia 48 hours after the operation. * % 3& * “With the exception of a patient who suffered from an attack of peritonitis, due to accidental exposure a week or more after the operation, I have met with but little difficulty in the after-treatment of other cases, and therefore have thought it unnecessary to extend this paper to a greater length.”—Am. Pract., Feb., '72. —- sº-º-º- HoME NEws. CoRRECTIONs Semi-Centennial Catalogue reported to date : Dr. W. S. Oneal instead of Dr. W. S. P. Neal. As THE CLINIC is constantly engaged in bringing to domestic notice the names of eminent foreigners it is no more than fair that foreign notices of domestic papers should be likewise duly chronicled. We observe thus in the last number of Virchow's Jahresbericht der Gesammt. Med., a notice of Prof. Dawson's case of hernia as presented to the Academy of Medicine, no less than ten different notices of various papers by Prof. Bartholow, and three of Prof. Blackman, besides the full abstract of Prof. Conner's paper mentioned a few weeks ago. The last number of the Paris Annales d’Oculistique contains a full abstract of Prof. Seely's paper on Stric- tures of the Nasal Duct, and the last number of the Archiv. f. Gynaekologie refers to a paper by a Cincin- nati Physician on the Morbid Anatomy of the Placenta. THE Commencement Exercises of this year will attract, it is hoped, a large number of the old graduates all over the land. It is proposed to establish an Alumni associa- tion to hold annual reunions each commencement. F. E. SUIR . . E. S. WAYNE IF. E. Suire & Co., WHOLESALE DRUGGDSTS, IM. A. N. U + A CT Uſ ER, IIST G. £HEMists AND PHARMAceutists, CINCINNATI, OHIO. Have constantly on hand a full assortment of sye), Ecºxed O)6. 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Medical Batteries, Barometers, Thermo- rameters, Hygrometers, Urinometers and Rain Gauges, of the most approved coustruction always on hand. All orders promptly and accurately filled. JAS. FOSTER, JR. dealing - F. S. SHACKLEFORD, ; *** * JAs. FostER, JR. & Co. S. W. Cor. Fifth & Race Sts., Cincinnati, 0. TIER). S-INT-INAL_A_IER,SIET’S No. 758 BROADWAY, New York HAVE been in the habit of applying and recommending the Truss manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it tar preferable to any I have ever examined. LEWIS A. SAY RE, M. D. Surgeon, Bellevue Hospital. From Prof. Willard Parker to S. D. Townsend, MI. D., Surgeon to the Massachusetts General IIospital, B EG leave to state for the benefit of all concerned, that I have known Dr. S. N. Marsh the last fifteen years. * * I am in the constant habit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with an v of the risks to the patient that exist in many of the plans suggested and attempted to be carried into execution. I have confidence in Dr. Mal sh as a gentleman of honor and integrity, and as such recommend him to the members of the medi- cal profession generally. • WILLA RD PARKER, MI. I.). Professor of Surgery, New York City IDr. S. N. Marsh's Patent Radical Cure Truss, and all other kinds of Trusses, Shoulder Braces, Supporters, Elastic Stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Cure Truss Offices of S. N. MARSHI & CO., No. 2 Wesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. w OPPOSITE THE HIGH STEEPLR, t|M|| Wilſº Mºſ SAML. P. THOMAS 167 EAST 34 TLI-ST., NE IV YO RIC, By Special Appointment Electrical Instrument Makers to the New York State Hospital for Nervous Diseases, MANUE ACTURERS OF PORTABLE ELECTRO-MAGNETIC MACHINES, Portable Galwamic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, 1870, and May 30th, 1871. * These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery Fluid. || || |||||—|| ||||||}} PERMANIENT EATTERIEs, For Hospitals and General Practitioners, TEIT IIECTIER, OTDIES. For Eye, Ear, Larynx, Nose, Uterus, Vagina, Bladder, Reč- tum, Feet, Phrenic and Sympathetic Nerves, Elec. trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. ->O->O->- EXTIRA (4TS FROMr TFIE O PINIONS OF THE IrOST JEMI NENT IMIEIM BERS OF THIS PROFESS E O N. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “Nothing cAN EXCEED THE EFFICIENCY AND CONVENIENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” We are authorized by Prof. IIammond to announce ern- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- provel and re-modified Instruments made by our Company. * \l EREDITH CLY MUER, M. D., Prof. of Diseases of the Neº- vous System and of the Mind, &c., &c.—“I consider their Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prof. of Surgery, St. Louis:—“In neat- ness, compactness and efficacy, they can not be excelled.” ALFRED C. G. AR RATT, M. D., Boston :-"In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” Similar Testimonials have been received from JOHN J. CRANE, M. D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A. MURRAY, M. D.; CHAS. E. BLUMENTHAL, MI. D.; E. C. SEGUIN, MI. D.; ALLEN MAYNARD, M. D., Cleveland, O.; Dr. C. WANNIE, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES KELLY, Florence, O.; Dr. JOHN BECKER, Brighton, Iowa; Dr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes- barre, Pa.; JOIIN J. CALDWELL, MI. D., Brooklyn, and many other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an Electrical Instrument for medical purposes. CALL OR SEND FOR CIRCULAR AND PRICE LIST, DE ALER IN English, French and Scotch GOOD's, 34 West Fourth Street, ("Z.W*("A.W.W.? 7"A. Are furnished to Officers and Soldiers on Government account. I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to, manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMES A. FOSTEE, 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cincinnati, Ohio, or 172 Jef- ferson Avenue, Detroit, Mich. List of Pharmaceutical Preparations, won.v. Irrazºn dº anoznan, FEIILADELPHIA. ELIX. PHOS, IRON, QUININE AND STRYCHNIA, - . . ." ELIXIR OF GENTIAN FERRATED, ELIXIR WALERIANATE OF AMMONIA, (Goddard’s Formula,) - - ELIXIR VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, Iron, with Phosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Iron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK, " . . ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER wine OFIRoş, citrate of Iron and Peruvian Bark, - - FERRATED CORDIAL ELIXIR, ELIXIR CALISAYA BARK, WINE AND BISMUTH, ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, - -- - - FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, - * TASTELESS COD LIVER OIL, TASTELESSCODLIVER OIL. FERRATED, BEEF. IRON AND WINE. e ELIXIRVALERIANATE OF STRYCHNIA, WINE OF rººm SYRUPSUPERPHOSPHATE OF IRON, - --- i lºw y ELIXIR OF BISMUTH, COMP. FLUIDEXT, BUCHU AND PAREIRA BRAVA. . . STUI PIPOSITOTER, TIES. Rectum, vaginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great care, and of every variety of combination. Lists sent on application. SPONGE TENTS.—For the Urethra, of every size and style made of finest quality of sponge. O' D C R LEs s AN ID PA. LATA B L E. ~ In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERs & BARTLETT, of Portsmouth, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. - Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachilic Affections, in Chronic Rheumatism, &c. • - The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. * We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. * JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. CAMARGO MANUFACTURING COMPANY, MANUFACTURERS AND IMPORTERS OF ../ſº SS * NS 3 . # *f AND Window Shades, 67 WºSz' A'oºziz Szºzzº, CINCINNXT, O, H. H. BRENEMAN, Proprietor, WILSON B Made to order of N. Y. M. Muslin and 2300 IIEAVY Linen, per dozen - - - $26 00 Wamsutta Muslin and 2100 HEAVY Lin- en, per dozen - - - - - - - - 33.00 Wamsutta Muslin and 1900 Linen, per doz. 30.00 Lonsdale Muslin and 1700 Linen, per doz. 27.0) First three qualities have ALL LIN EN Cuffs and Neckbands. At above prices Cuffs are attached. Same quality of our own manufac- ture, ready-made, $3 per dozen less. Perfect satisfaction given or money cheerfully refunded. * . . . * Also import and Manufacture Men’s Furnish- ing Goods. . . .” - rikes. Opera-House, Fourth Street, Cincinnati; 931 Wabasha Avenue, and ss West Washington * - Street, Chicago. |M. A. F. K TVA IN'S NIEVV B O O IX IS NOVV READY FOR CA N VASSE FRS. It contains over 600 pages of read:ng matter, with 250 engravings, designed expressly for this work, by the beft artists in the country. Agents now at work upon it are meeting with unparalleled success. Agents at Circleville, O., reports 25 orders in 2 days; one at Louisville, Ky., reports 175 orders in 8 days; one at Middletown, Conn., reports 200 orders in 12 days; one at Cincinnati, O., re- ports 250 in 12 days. Early applicants secure choice of territory. For circulars, terms, &c., address NETTLETON & CO., 161 Elm Street, Cincinnati, O. BASCOM & CARFENTER, Stationers, Printers -AND-. Blank Book Manufacturers, 136 v1.NE stre+ET, syssWSNs º: E. D. ALBRO & BRO. IMPORTERS AND MANU FACTUREIRS OF FOREIGN and DOMESTIC WOODS In Veneers, Boards and Plank, frº-Mikº','!-Biliń'milli-Biº": The only house in the Western country that saws Spanish and Mexi- can cedar for Cigar-Box Makers We import our own wood direct, and can sell at prices to compete with any and everybody. Also saw and keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. - Office and Warerooms, 136 and 138 West Second Street, Veneer Min, 507, 509, 511, 513 & 515 W. Sixth St., CINCINNAT1. sºlº- } º º, ºr AS ºs. Nº. º * —d : * fºr .. , , , . --- . . . . . . - * . . . º: * : * ~ *-*. iſ . º. WSºjº º 'º lºssº º |ºilº. ºº:: ix. E.; --- º × sº * . J. > *...º.º. Ex. xº F. E3: . * Tº , ſº aga. É. Ex- ** ſiliºsºls. E.--~~~~ ; : : º CINCINNATI. —º- FA C U L T Y. J A M ES G R A H A M, M. D., DEAN, IProfessor of the Theory and IPractice of IMCedicine and Cli •. S nical Medicine. -* *. , ... • * * : * ROBERTS BARTHOLOW, M.D., w. W. DAWSON, M. D., Professor of Materia Medica and Therapeutics. Professor of Principles and Practice of Surgery and Clinical Surgery W. H. GOBRECHT, M.D., - - -º- ' - C. D. PALMER, M.D., * * * Professor of Anatomy. Professor of Medical and Surgical Diseases of Women. P. S. CONNER, M.D., T. A. REAMY, M.D., Professor of Surgical Anatomy. Professor of Obstetrics and Diseases of Children. W. W. SEELY, M.D., JOHN L. CLEVELAND, M.D., Professor of Diseases of the Eye and Ear. Demonstrator of Anatomy. SAMUEL NICKLYSS, M.D., CHARLES KEARNS, M.D., Professor of Physics and Medical Chemistry. Assist, aſ to the Chair of Surgery. *... . . . . . . . . . * * J A MC E S TC - W H IT TD AL ES Jº, ER, • ** * * * Professor of Physiology and Secretary of the Faculty. agº"T"-se T. Louis Baown, Prosector of Anatomy. s —- --~~ Janitor, Collège Building, Sixth St., bet. Vine and Race. Printed and Published by Norris & M cFRY, Medical College of Ohio Building, Cincinnati. THE CLINIC, PUBLISHIED EVERY SATURDAY. TER M S-$2.00 a Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editor: All Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer. Vol. 2. C IN C IN N ATI, F E B R U A R Y 24, 1872. —º No. 8. JAS. T. VV HIT TAKER, M. D. Editor. Nq. 101 West Ninth Street, Cincinnati. -A-SSOCIC A.T.E. H. DITOIES. W. W. D.Awson, M. D. TILAD. A. ReAMy, M. D. IP. S. Con NER, M. D. C. D. PALM :R, M. D. W. W. SEELY. M. D. SAMUEL NICKLEs, M. D. CIIAs. KEARNs, M. D. JNo. L. CLEVELAND, M. D. Roperts BARTHoLow, M. D. W. W. SEELY, M. D., sº me º a sº tº TREASUREIt. No. 118 West Seventh Street, Cincinnati. C L U B R A T E S, 4 Copies to one address...................................................... $ 7.00 6 & & 4 10.00 12 ſ & & 4 18.00 C O N T E N T S. - * -º- Page: orrorNAL ARTICLEs Medical Electricity and Medical Electrical Apparatus—The Eee- tric Chamber of the Good Samaritan Hospital, by Roberts - Bartholow, M. D & & e º e º ºs e º ſº tº a º sº e s m s m ºn tº e s e º e º e º a gº tº e º 'º e s ſº tº e º 'º e º 'º e º 'º - ºr e º 'º e º e a 8? TRANSI LATION Cancroid, Impetigo, etc., Their Diagnosis and Therapy, by M. A. Duvergie, (From the Bulletin Therapeutique, Nov. 30, 1871)........90 Coal Dust in the Lungs, (A Chapter from Hirt's Staub-Inhalations Krankheiten, Breslau, 1871.)..................................................... 9] SCIENTIFIC NOTES Diagnosis of Syphilis by the Microscope—Sarcina in Blood........ 93-94 M. IE DICALL NEWS A Curious Suggestion—Quacks excluded from Penn. Hospital—A Facetious Review.................................................................. 94-95. CORRESPONDENCE Letter from Dr. Juler—The Recent Bandaging Contest.................... 95 CILINICAL, MIEN IORANIDA Turpentine in Acute Affections of the Middle Ear–Sºin Puncture s in Anasarca Qſ HOME NEWS................................................................................ 9( The Spring Course of 1872 90 *- * * * * * * * * *-*. WE hear a good deaſ in Cincinnati about the effects of our smoky atmosphere. Our information on this subject hitherto has been mostly in the way of glitter- ing generalities. THE CLINIC commences a series of translations in this number with some positive knowl- edge on this subject. Further in detail is presented, also, of Lostorfer's great discovery of the “syphilis corpuscle.” " coaxN te co- Fashionable Hatters, lyſportERS AND MANUFACTURElis 0F EA}}{ES” FºrS, 92 WEST FOTTERTH ST. Opposite Post Office, CINCININATI. & Special Inducements to Medical Mem. s #: º *A. OD jºsº. 32. WºST FOURTH: Sº &---. Nº CINCINNATI, OHIO: e we wº. -- *- J. TAFT, W. TAFT. Editor Dental Register J. & W. TAFT, IDENTIsTs 117 WEST FOURTH STREET, CHN CIN NATI, O. Registers A Monthly Journal, CONTAINING 48 PAGES, Devoted to the Interests of the Dental Profession, MARviv's COTD IT IIITVTIEHIER, GDIT_ O D O R. L. E S S A. IN ID PA I, A. T A E I L IE • In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERs & BARTLETT, of Portsmouth, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. * Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachilic Affections, in Chronic Rheumatism, &c. The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its meri” are tested by the medical profession the more highly will they be appreciated. The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufact ture of the Oil, have retired altogether from its sale, which is in our hands only. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. ROBERT CLARKE & Gū’S, LIST . OF NEW Mail, iTºm Mºulis in: GREEN'S PATHOLOGY AND MORBID ANATO MY, 8vo Cloth. $2 5c - - DUCHENNE'S LOCALIZED ELECTRIZATION. 8vo. $3 ot DILLENBERGER ON WOMEN AND CHILDREN’S DIS EASES. 12mo. $1 75 - BENNETT ON PULMONORY CONSUMPTION. 8vo. $1 5¢ FIRST HELP IN ACCIDENTS. 12mo. $1 50 BEASLEY'S DRUGGIST RECEIPT BOOK. 8vo. $3 5o ECHEVERRIA ON EPILEPSY. 8vo. Cloth. $5 oc HOWE ON EMERGENCIES. 8vo. $3 oo HAMMOND ON NERVOUS DISEASES. 8vo. $; oo RINDFLEISCH'S PATHOLOGICAL HISTOLOGY. $6 oc WARINGS’ PRACTICAL THERAPEUTICS, 2nd Am. Ed. 8vo. Cloth. $5 od Leather. $6 oo SCUDDER'S SPECIFIC MEDICATION. 12mo. Cloth. $2 5c TANNER'S HANDBOOK OF OBSTETRICS. 12 mo. $2 oc VAN BUREN ON DISEASES OF THE RECTUM. 12mo. Cloth. $1 5o FLINT’S EXAMINATION OF URINE. 12mo, Cloth. $ 1 oc VOGEL ON DISEASES OF CHILDREN. 8vo. Cloth. $4 5¢ BEARD AND ROCKWELL’S MEDICAL AND SURGICAL ECECTRIGITY. 8vo. Cloth. $4 5o ATTFIELD'S MEDICAL CHEMISTRY. 12mo. Cloth. $2.75 Leather. $3 25 BARTHOLOW'S HYPODERMIC MEDICATION. Cloth. $1 5o TURNBULL’S DISEASES OF THE EAR. 8vo. Cloth. $5 od TILT'S CHANGE OF LIFE. 8vo. Cloth. $5 od NEUMANN'S HAND-BOOK OF SKIN DISEASES. Cloth. $4 oo ANSTIE ON NEURALGIA. 8vo. Cloth. $3 oo. PANCOAST'S OPERATIVE SURGERY. 4to., with many - plates. $1o oo HOOD ON BONE SETTING. 12mo. $1 5o RINGER'S HAND-BOOK OF THER APEUTICS. 8vo. $4 oo I 2, TIMO. 8vo. HOLBROOK’S PARTURITION WITHOUT PAIN. 16mo. - $1 oo PROCTER'S LIGHT SCIENCE FOR LEISURE HOURS. 12mo. $1 75 - BERNARD’S PHYSIOLOGY OF THE HEART: 50 cts. BARNES’ OBSTETRICAL OPERATIONS. 8vo. $4 5o NICHOL’S FIRESIDE SCIENCE. 12mo. $1 5o. WOHLER'S MINERAL ANALYSIS. 12mo. Cloth. $3 oc PLATTNER'S MANUAL OF ANALYSIS WITH THE BLOWPIPE. 8vo. Cloth. $7 5o JEFFRIES ON THE EYE. 8vo. Cloth. $1 oo MANSFIELD, A THEORY OF SALTS. 8vo. Cloth. $4 oo JEFFRIES ON THE SKIN. 8vo. Cloth. $1 oo - GARDENING FOR PROFIT. 12mo. Cloth. $1 5o PRACTICAL FLORICULTURE. 12mo. FULLER'S SMALL FRUIT CULTURE. 12mo. Cloth. $1 5o WOOD WARD's countRY HOMES. 12mo. Cloth. $1 5c DARWIN'S ORIGIN OF SPECIES. 12mo. Cloth. $2 oc ARTHUR'S TREATMENT AND PREVENTION OF DE- CAY OF THE TEETH. 12mo. $1 5o TYND ALL ON LIGHT AND ELECTRICITY. 12mo. $1 25 THE AMATEUK MICROSCOPIST. Small 4to. $1 75 BOOKS IN PREPARATION. BRYANT'S PRACTICE OF SURGERY. BARNES ON DISEASES OF WOMEN. ROBERTS ON RENAL DISEASES. GUERSANT, SURGICAL DISEASES OF WOMEN AND CHILDREN. Medical, Scientific, and other Catologues sent on application. * Any book in the above list sent by mail or express, free of charge on receipt of price. . Cloth. $1 5o 65 West 4th Street, Cincinnati, Ohio. § William Autenrieth, No. 71 west sIXTH stre+EET, BKTWEEN WALWUT Año VINE, cincinnati, ohio, MANUFACTURER OF AND DEALER IN || || || |||||||| Abdominal Supporters, Trusses, TUB-F00T SHOES, SPINAL APPARATUS, ETſ . Keeps constantly on hand a full variety of Metalic and ERubber syringes, Stormzach Pumps, Etc. stockINGs Foſt vanicose veins, Special attention given to the fitting of Apparatus for Deformities. B& Agent for DR. L. A. BABCOCK'S §ilver Uterine Supporter, —ALSo— DR. AHL'S POROUS FELT SPLINTS, ~ALSO– DAY's spi, INTs -AND- S. W. Elliott's Saddle-bags List of Pharmaceutical Preparations, MANUEFACTURED EY Jø/ZW WJZZZZ & B/P0ZZZºº, FIHºrrº.4\D.E.L.F.H.I.A. —dº- ELIX. PHOS, IRON, QUININE AND STRYCHNIA, ELIXIR OF GENTIAN FERRATED, ELIXIR WALERTANATE OF AMMONIA, (Goddardi's Formula,) ELIXIR VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, Iron, with Phosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Iron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK, º ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, * COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER WINE OF IRON, Citrate of Iron and Peruvian Bark, FERRATED CORDIAL ELIXIR, ELIXIR CALISAYA BARK, WINE AND BISMUTH, - ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, TASTELESS COD LIVER OIL, TASTELESS COD LIVER OIL. FERRATED, BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and sherry wine, ELIXIR WALERIANATE OF STRYCHNIA, WINE OF PEPSIN SYRUP SUPERPHOSPHATE OF IRON, y ELIXIR OF BISMUTH, COMP. FLUIDEXT. BUCHU AND PAREIRA BRAWA. STUIEPEPOSITOTER, TIES. Rectum, Vaginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great care, and of every variety of combination. Lists sent on application. SPOINGE TENTS.–For the Urethra, of every size and 8tyle, made of finest quality of sponge. FOSTE: Fº’5 152 ALTTE INT Are furnished to Officers and Soldiers on Government account. I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMES A. FOSTEER, 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cincinnati, Ohio, or 172 Jef- ferson Avenue, Detroit, Mich. ..e. -- SAML. P. THOMAS T.A.. I I, OR, IDEALER IN English, French and Scotch GOOIDs, 34 West Fourth Street, ("A.W'6"A.W.W.??"}. ||||||}|| || ||M|| 167 EAST 34TH-ST., NEW YOI: R, By Special Appointment Electrical Instrument Makers to the New York State Hospital for Nervous Diseases, MANUFACTURERS OF POP TABLE ELECTRO-MAGNETIC MACHINES, Portable Galwamic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, 1870, and May 30th, 1871. These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery Fluid. |||||| ||||||—|| ||||||| E’ERMIANENT BATTERIEs, For Hospitals and General Practitioners, -TET IIECTIER, OTDIEGS- For Eye, Ear, Larynx, Nose, Uterus, Wagina, Bladder, Rec- tum, Feet, Phrenic and Sympathetic Nerves, Elec. trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. EXTRA 64TS FROIſ THE OPINIONS OF THE MOST JEIHINENT MEMBERS OF THIS PROFESS / ON. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “Not HING CAN EXCEED THE EFFICIENCY AND CONVENIENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” We are authorized by Prof. Hammond to announce eun- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- proved and re-modified Instruments made by our Company. * MEREDITH CLYMER, M. D., Prof. of Diseases of the Ner- vous System and of the Mind, &c., &c.—“I consider theºr Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prof. of Surgery, St. Louis:—“In neat- ness, compactness and efficacy, they can not be excelled.” ALFRED C. GARRATT, M. D., Boston :-"In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” Similar Testimonials have been received from JOHN J. CRANE, M. D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A. MURRAY, M. D.; CHAS. E. BLUMENTHAL, M. D.; E. C. SEGUIN, M. D.; ALLEN MAYNARD, M. D., Cleveland, O.; Dr. C. WANNIE, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES KELLY, Florence, O.; Dr. JOHN BECKER, Brighton, Iowa; Dr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes- barre, Pa.; JOHN J. CALDWELL, M. D., Brooklyn, and many other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an Electrical Instrument for medical purposes. -- CALL OR SEND FOR CIRCULAR AND PRICE LIST. DIVIDED MEDICINES, The Divided Medicine Com’y, CINCINNATI, OHIO. The Company have the honor of bringing to the notice of the Profession, this NEW AND ExCEEDINGLY PRACTICAI, METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. The Divided Medicines are prepared by FREDERICK KRAUs, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MORE. sº - The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every square will consequently contain accurately measured quantities. But not only SolueIE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINES. * - - |} * This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, ; , , , ºo, and even idoo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE TO SPOIL BY ANY LENGTH of TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calls with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. For Samples, Price Lists, and Agencies, address IECX 2688, Or FRFDERICK KRAUS, Chemist and Druggist, Walnut Hills, Cincinnati, O. MR. FREDERICK KRAUs: CINGINNAT1, February 15, 1871. Dear Sir—The specimens of your “ Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: . - SULPH:MORPH II....................... % grain in each square. ARSEN: ACID..........................1-20 grain in each square. ** CH IN INI .......................] ** * * 46 CALOMEL 34 “ “ “ “. COPPER ....................... 3% 66 ResPECTFULLY You Bs, E. S. WAYNE, Analytic Chemist. T TELIED CT I I INT I C . 85 Vol. 2..] S A T U R D A Y, F E B R U A R Y 24, 1872. [No. 8. | º *======####, B I re- Q----s -* Tººl º *Tº º 3 º # =}| º: Gymnº * *- T H E C O N S T A N T C U R R E N T B A TT E R Y A N D R E G U L A T O R () F T H E E L E C T R T C C H A M B E R O F T H E H O S P IT A L OF T H E G O O D S A M A R IT A. N. ( for description see meat page.) 86 [FEB. 24, 1872. T THITE C T , T IN IT. C. M IELDICAL ELECTRICITY AND MIEDICAL IELECT RICA L AIP PARATUS. The Electrical Room of the Good Samaritan Hospital. BY ROBERTS BARTHOLOW, M. D. Number 7. The applications of electricity to the treatment of disease have become so numerous and important, that no hospital can be considered properly provided, which does not contain the most approved electrical apparatus. We can now say that a hospital in Cincinnati is as By thoroughly equipped in this respect as any other. % == % º ſt ~ 2: .3 ::: * º - ſ \\ * * * º, * | º Bºº - |# §: t gaſ;| | º | º i. W Hºº ; | ||||||| [: the intelligent liberality of a gentleman of this city, the Good Samaritan Hospital now contains an electrical room furnished with all the appliances needed for the practical uses and scientific study of electricity. The patients will have the advantage of the undeniable good which comes of the use of electricity in suitable cases; the therapeutical resources of the Staff will be greatly increased, and the numerous students who attend the clinical courses will have the opportunity to learn all that has been, and is being accomplished in this depart- ment of medical Science. It is, therefore, with unmixed gratification that we submit to our readers an account of the Electrical Room of the Good Samaritan Hospital. The room is in close juxtaposition to the clinical | | ...~~ lecture room, and contains a permanent galvanic battery of sixty elements with regulator and the various forms of electrodes; an induction machine; a galvano-caustic battery, and galvano-caustic electrodes; and an exten- sion chair for the comfortable placing of the patient. Galvanie Battery.—The cups of the permanent battery are that modification of Daniell’s, known as Siemens and Halske's, and were made in the most excellent manner by Mr. Brown, a medical student and electrician of this city. This form of battery was originally intro- duced by Remak, and is now almost exclusively used by the continental electricians. It has the great merit of being truly constant; it remains long in action with- out losing power, and is very durable. As it has already been described in the columns of THE CLINIC it is not necessary to enter into any further particulars. The cups of the battery are connected with the Regu- lator of the Galvano-Faradic Company. This admirable instrument is provided with galvanometer, current wº assº . …" ; , , ſº * --~~ interrupter, polarity changer, current modifiers, and current selectors, thus permitting to the operator the production of all the electro-physiological and electro- therapeutical effects. On the left side of the regulator, communication may be made with 2, 4, 6, 8 and 10, and on the right with 10, 20, 30, 40 and 50 cups. The current flowing through either or both poles may be further modified by the right and left hand modifiers. The cups are contained in a neat upright walnut case in shape like a book case, and the regulator is placed on the table in front, which with its tiers of drawers resembles an office desk. (The first page wood-cut shows the arrangement). Wires pass from the regula- |tor to the lecture room so that applications may be FEB. 24, 1872.] made in presence of the class. In the same way one or all the wards of the hospital may be brought into direct communication with the battery. Faradic Machine.—The Faradic instrument selected, is the ingenious and excellent arrangement of the Galva- no-Faradic Company. It is represented in Fig. 2, (p.86) with one cell, but the hospital instrument is the “double cell battery.” The cellis Stoehrer's modification of Bun- sen's carbon battery, and consists of two carbon plates and one zinc plate. By means of the graduated hinged rod A, the zinc element is raised from or lowered into the exciting fluid, so that when not in use the zinc may be preserved from loss. A very important feature of this instrument is the “adjustable elastic fork” attached to the rheotome by which the operator may control the T TEI IET: C T IIINT I C - rapidity of the interruptions, making them slow or fast at will. In the instruments ordinarily in use the inter- ſº #º | | || º }l H | § l sº !lliºli tº ºr sº .* º | g * ſºlº { #98. ſ § º i | |jº #|\# $ - * #: ### g ! {: I 87 different degrees of susceptibility evinced on each occasion. As the strength of the primary current is in- creased by drawing out the movable coil 4, we count from left to right when we apply that current. The in- tensity of the secondary current is increased by pushing the movable coil inwards. In this case we make the record from right to left. - Galvano-Caustic Battery.—The engraving below rep- resents the hospital galvano-caustic battery, an im- proved modification of Stöhrer's and Grenet's. There are four capacious glass cells, each containing four large . zinc and three carbon plates. This is the “American Galvano-Caustic Battery” of the Galvano-Faradic Com- pany. It consists of zinc and carbon elements, the ex- citing fluid being a solution of bi-chromate of potash in dilute sulphuric acid. The elements may, as will be perceived on examination of the engraving, be raised {, } |º | - | º | | 1. Lº / \ º ºf sº -*-* … --, -se------------ ruptions occur so rapidly that the muscles are kept in a state of tonic contraction; whereas, in this, there may be, by regulating the vibrations of the hammer, distinct contraction and relaxation. Any electro-therapeutist will readily appreciate the advantages which belong to such an arrangement. Both the inducing and the in- duced currents are obtained from this machine, and an arrangement exists for changing from one to the other and for reversing the polarity of either. This instru- ment has the further advantage of a cell cover (Powell's Hydrostat F) which renders it perfectly portable with- out the necessity for emptying out the liquid. G, represents an indicator or scale affixed beneath the movable coil 4, graduated both ways, to enable the operator to make an exact record of the electricity ap- plied to his patient at each seance, thus determining the out of or lowered into the exciting fluid. When the action flags, air is blown into the fluid by the bellows. This battery is accompanied by a case containing all the galvano-caustic electrodes in situ. (Fig. 4, p. 88.) 1. Handle for looped electrodes. 2. Stem for loops. 3. Long tubes for laryngaeal application, for nasal polypi, etc. 4. Short tubes for loop. 5. Universal handle.—The upper end of each of the other cauteries can be inserted in the socket of this handle. 6. Platina point cauterizer for concentrated cauteriza- tion, counter irritation, etc. 7, 8, 9. Dome cauteries for cauterization of sinuses, bleeding surfaces, bases of ulcers, places where cicatricial 88 [FEB. 24, 1872. T TE:L THE CIT IIIN T C. contraction is desired, for the destruction of small growths, etc. 10. Long curved stem cauterizer for cavities, sinuses, €tC. 11. 12. 13. 14. 15. 16. 17. Straight stem cauterizer. Galvanic knife cautery. Right angle loop, which may be used as a knife. Galvanic curette. • Beak cautery for counter irritation. Short curved stem for cavities, sinuses, etc. Pocket for platina wire and porcelain domes. † * 7 O/ZZZ Fig. 4. This case contains most of the apparatus necessary for the surgical uses of electricity. It need hardly be remarked how important these uses are, and to what an extent the various galvano-caustic instruments are ap- plicable to the treatment of lesions hitherto remediable only by the surgeon's knife and to some, indeed curable by no other methods. For the benefit of the skeptical it may be stated that polypi, have by the galvanic loop been removed from the naso-pharyngeal space, from the larynx and from the uterus. By the same means the cervix uteri has been amputated and hemorrhoids ex- cised. By the electrolytic decomposition tumors and glandular enlargements have been resolved, aneurisms - consolidated, and hydatids of the liver destroyed. The needles for electrolysis are represented in Fig. 5. Fig. 5. For galvanization of the male bladder and urethra, the electrical room is provided with the catheters and sounds shown in Figs. 6, 7 and 8. For the electrical treatment of uterine maladies we have the various forms of electrodes represented in Figé. 9, 10, 11, 12, 13, 14, 15, 16 and 17. E::=>==E-BE:----- FE-Erz:TET=-EEE------------------ --- FEB. 24, 1872.] TIEI IEH C T , IIINTI C. 89 Fig. 18 represents Duchenne's ear electrode and Fig. | 19, a laryngeal electrode. Duchenne's electrodes for electrizing muscles is shown in Fig. 20. Beside the foregoing the electrical room is supplied with various electrodes for the general purposes of elec- trical application. Some of them are represented below. - Fig. 21. Sponge covered electrode for feet. - Fig. 22. Phrenic nerve electrode. Fig. 23. Metallic brush electrode. In the following woodcuts are shown various forms of single and double electrodes. Figs. 24, 25, 26, 27, 28. | n Winſ; º sº | ºt º º . º 90, [FEB. 24, 1872. T IEEE IET; C T , T: INTIC. Cancroid, Noli-Me-Tangere, UIcerous Impetigo Rodens, and Non-Ulcerous Impetigo Rodens. Their Differential Diagnosis and Therapy. BY M. A. DEVERGIE. Member of the Academy of Medicine, Honorary Physician to the St. Louis (Paris) Hospital, From the Bull. Therap., Ncy. 30, 1871. Continued from No. 7. Varieties and species of impetigo rodens. I have divided impetigo rodens into two varieties and species, the non-ulcerous and ulcerous. The first shows itself under two different forms. In the first is presented the ap- pearances of a lenticular circumscribed spot of sebaceous- acne, that is to say, of a grayish slightly-prominent growth, a little greasy and capable of being detached either by a fatty substance applied for some hours, or by a light poultice. This form is very often multiple, situated upon the eyelids or upon the side or back of the nose; and, despite its insignificant appearance, it leaves the prints of its existence upon the skin, and re- appears at the same points. In the other form, the disease has at its outset a more pronounced character, as a vesiculo-pustular affection. It shows itself at but a single point, most usually at the internal angle of the eye. It originates in some small inperceptible vesicles attended with the sensation as of a fly walking upon the skin. The vesicles open spontaneously—and become changed into a small, wrinkled, yellowish crust. The whole of these morbid productions occupy a space the size of a large pin-head. This state of things remains stationary for a longer or shorter period, ten, fifteen, twenty days or more, during which time the crust falls off, leaving an almost in perceptible cicatrix. A second eruption similar to the first then occurs, having for its point of departure the extreme circumference of the cicatrix produced by the first. This eruption advances in such a manner as to extend the length of the diseased patch and slightly its breadth. But such is the slow- ness of the development of the disease that it is only after many months, Sometimes many years, that there is noticed a diseased patch, partly cicatrized, partly covered by a crust, occupying a space of a half centi- metre, oval in shape, and causing real inconvenience only as it affects the expression, thus becoming disagree- able to the patient. So little is the inconvenience that results from it, that patients do not ordinarily consult a physician for two or three years. One very remark- able thing is, that this sort of affection is so very com- mon in men and rare in women. Without attempting to estimate with any exactness, I would say that it will be met with ninety times in a hundred in men. With ulcerous impetigo rodens it is altogether different, –E– for it probably attacks women as often if not more often than men. Whenever non-ulcerous impetigo rodens has attained the size that I have spoken of its surface is seen to be composed of two parts, of differentappearances; the one shows the skin depressed, indicating a cicatrix, the other is covered with a small impetiginous crust, rough to the touch, of a grayish color, and made up of the debris of the vesicles. This impetigo rodens may last for fifteen years and present the same characters, (aside from its increased dimensions,) without changing its nature or appearance. The ulcerous impetigo rodens is ulcerous from the start. Commencing with the appearances of impetigo, there is formed in a little while a very small ulceration, Scooping out the tissues. It enlarges by a - series of vesiculo-pustular eruptions, until it has attained such dimensions that the patient is obliged to dress it with cerate or pommades, which modify the primitive character of the eruption. Then the borders of the ulcer are elevated, somewhat indurated, bleeding upon the slightest touch, even on the least lifting of the little bit of charpie adherent to it. But the induration very rarely reaches the intensity of the cancroid. This variety shows itself tipon the cheeks, in the neighbor- hood of the nose and eyes. It is often multiple, spreads, destroying the angles of the lids, and giving rise to pus more or less well-elaborated. It is not acutely painful, and the pain is never of the lancinating character. There' is another disease with which the authors I have men- tioned, particularly Alibert and Bateman, have confound- . ed it; that is lupus. But there exists between the two affections very marked differences. First as to locality: lupus attacks most commonly, the end of the nose and upper lip. If it appears on the cheek it is generally but by extension, or if it commences there it is especially in the center and lower part of it. Again lupus may be developed upon any part of the body. Ulcerous impetigo rodens almost never shows itself except in the neigh- borhood of the eyelids,and one of their angles, or on the side of the nose, always the upper part of the nose. Lupus is never clearly circumscribed, its circumference is always surrounded by reddened, thickened skin, the turgescence of which is insensibly lost in healthy tissue. In impetigo rodens the disease is so sharply circumscribed, that the transition is abrupt from the diseased to healthy tissue. Lupus is developed almost always in those of lymphatic temperament and more or less scrofulous, save certain exceptions in this respect, in which the ev- idences of scrofula are not clearly apparent. If scrofula. has relations with impetigo rodens, which I do not dombt in certain cases, judging from appearances, they are far from being so marked as with lupus. To be Continued. —º-e-tº- HoNORS DECLINED.—Profs. Billroth and Brücke, of Vienna, have been offered chairs in the University of Strasbourg. They have, however, decided on remain- ing in Vienna. # FEB. 24, 1872.] T IEI IEH C T , II INTIL C. 91 C O AL ID U S T IN T H E L UN G. S. Anthracosis Pulmonum (Stratton), The Coal or the Miner’s Lung. BY DR. LUDWIG HIRT, (Breslau). A Chapter selected from the Author's work on “The Diseases of Labor- ers from the Inhalation of the Manufactory Dusts” (Die Stanbinhala- tions Krankheiten, Breslau, 1871.) SYNONYMs: Black Lung Infiltration (Gregory), False Melanosis (Marshall, Rilliet), Coal Miner's Lung, Coal in the Lungs (Graham, Thompson), Melanidie (Maurice), Encombrement Charbonneua, des Poumong (Riembault), Black Spit, etc. The history of this affection extendsbacksome distance in the past. Investigations concerning the penetration of dust into the lungs were excited by the discovery of the black coloring of the lungs, the lung pigment of Virchow, which was thought to depend upon the inhalation of fine particles of coal. All attention, then, was directed, especially, to the penetration of coal dust in the pulmo- nary tissue, and it is only in quite recent times that the action of other kinds of dust was subjected to accu- rate investigation. To an Englishman, Pearson, is due the credit of having been the first to establish this view. His statements, it is true, were not always correct yet they broke ground and led to valuable investigations. He based his view (1813) on chemical examinations of the black coloring matter of the lungs and bronchial glands and demonstrated their identity with carbon. As we have convinced ourselves by most searching in- vestigations of the Paris Bibliothéque Impériale, Laennec was not the first to express a suspicion of this kind. Neither the Mémoire of the Bulletin de la Faculté de Médecine de Paris, 1806, II, concerning Melanosis, cited by Zenker, nor in another of Lænnec's works written in 1819 is there any mention of this subject. It was only in 1819 in his Traité de l'Auscultation, tom. II. that he says that “He has several times entertained the suspicion that these black particles may originate from lamp smoke and other burning substances used in heat and illumination. This view received probability when Gregory (1831) first published a case in which the pig- mentation was confidently attributed to the inhalation of coal dust. The lungs in this case presented, besides the usual pigmentation, alterations in their tissue; they were lungs, moreover, of a coal miner. Similar contribu- tions were offered in England by Thompson, father and son, Philp, Simson, Stratton (author of the name anthracosis), Gibson, Mackela, Hamilton and others. The last mentioned furnished a report on the case of a moulder in a foundry. In France Andral (1837) pub- lished the case of a coal worker observed by Béhier; then and especially the anatomist Bourgery, Piorry, Tardieu, Bouillard, Villaret Reimbault all attempted by continued observations to establish the suspicion as a certainty. Maurice called particular attention to the fact that the material of the lungs of workers in coal was distinguishable from the true pigment of the lungs by the fact that the deposit was but little affected by all the acids and alkalies; it was therefore not pigment, it was coal. In Germany, among the oldest works should be men- tioned those of Erdmann (1831), and Brockmann (1851). The last mentioned claims besides the asthma metallarg- icum pneumonodes still another pulmonary melanosis which is not identical with anthracosis. The pigment found in the lungs is not a vegetable coal but a mixture of the vegetable and animal. These works did not meet much consideration at first in Germany since no one seemed able to regard these depositions as anything but true pigmentation. Even Virchow was at first opposed to the view of their carbonaceous nature, since the method of their deposition “the entire absence of pigment in the interalveolar septa and the immense ac- cumulation under the pleurae are facts which correspond very little to a progressive absorption.” Oppert (1857) supported Virchow. Then appeared Tranbe’s widely known and highly interesting and instructive case. It was that of a laborer who had long been engaged in an atmosphere charged with charcoal; who had expect- orated masses of black matter which the microscope demonstrated to contain fine particles of charcoal. These particles were irregular, angular, and of consider- able size; they were found some within, and some with- out the cells, some even in the act of penetration. They showed in the lungs a peculiar ruby-red color. On autopsy the lungs were found perfectly black and the fluid escaping from the surface of section was seen to contain particles of coal. While, now, there appeared in France the valuable investigations of Ruborn, Crocq, and others there was published in Germany by Seltman a most thorough work following the recent observations of Traube, Cohnheim, Kussmaul, Rosenthal, Levin, etc., more and more clearly determining the nature of our subject. Förster and Friedreich raised the last voices in doubt; they still held fast to the doctrine of pigmen- tation. Last of all came forth the classical work of Zenker, who demonstrated the penetration in lung tissue of particles of iron dust in the same manner as coal, now an accepted fact, overcoming by this announce- ment the very analogy postulated by Friedreich himself and silencing, thus, the last doubter on the whole sub- ject. This closed the long line of disputants pro. and con, to open, as we have already intimated, a new field for wider investigation, namely, besides the penetration of iron into lung tissue that of still other kinds of dust and thus to render it possible to draw from the path- 92 [FEB. 24, 1872. TIEEE IEH C T , I INTI C - ologico-anatomical condition of the lungs on autopsy a relatively certain conclusion as to the avocation of the individual during life. The most recent experiments of Slavyansky have shown that substances in minute subdivision entering the trachea may penetrate into the alveolae of the lungs and into the pulmonary tissue of animals, and may reach thus the lymphatic glands and the blood, moving most probably with the fluids of these canals respectively. With this there remains to mention still one other work, Dressler's, in the Prager Viertel-Jahrschrift to which we shall return, for a moment, later. Having thus made ourselves familiar with the cardinal points of the history of this, in every sense, so interesting affection we may turn to the consideration of its sym- tomatology and cause. Concerning symptoms, then, it is first to be specially and emphatically remarked that they correspond in no way to the marked anatomical lesions found present. The single characteristic, path- ognomonic symptom is the black expectoration of the laborer, and this must continue a long time after re- moval from the conditions of its production. Such ex- pectoration during and immediately after labor is totally without value in the diagnosis of anthracosis as it then comes from the trachea and larger tubes only. This ex- pectoration has been subjected to frequent and thorough investigation more especially by Friedreich, Traube, Sanders and many others.” According to the first mentioned of these investigators the black-wedge or heedle-shaped coal particles are found inside of the cells a view with which Traube and Mannkopf's observa- tions do not coincide. Traube, as already stated, found these coal particles partly inside the epithelial and mucous cells while Mannkopf found them only outside of the same. Friedreich maintains that this condition described, namely, the presence of coal particles partly enclosed in the cells and partly free—a condition which is really almost without exception in the lungs of coal miners—is only encountered in exceptional cases. Besides the particles of dust and the nucleated cells en- closing them, [lymph-like bodies are often observed in the sputa and not seldom also elastic fibres and tissue detritus. Except the presence of these constituents of the sputa just described, and their presence too, as we once again emphatically state, long after the avocation has ceased, there is no characteristic symptom which may establish the diagnosis of anthracosis during life. This we shall see exemplified in the closer investigation into the course of the disease which shall now engage UlS. According to the different views of different authors two or three different stages are to be recognized in this affection. If different stages are to be recognized, in general, it is best to accept those of Crocq+ and Tardieu. Crocq states that the first stage is marked by an anaemia of high degree with an occasional occurrence of the expectoration described as characteristic. Associate with these symptoms is a light dyspnoea [Kurzathmig- keit, short breathedness] with a sense of weariness towards evening. The second stage is caused by an ac- cumulation of coal particles and a corresponding dim- inution of the capacity of the lungs. It is evidenced by symptoms of asthma and is distinguished from other forms of this disease by its sudden inception, long dura- tion and imperfect remissions. That Crocq has gone too far in this view and that the disease here is nothing else than a simple emphysema induced by bronchial catarrh of many years duration, a bronchial catarrh not directly caused by coal dust inhalations, seems now, established beyond doubt. Tardieu characterises the second stage by the occurrence of anaemic manifestions, a pale, bluish-gray teint and wearisome gait. The dyspnoea is marked, all the respiratory muscles are strained, cough is at times continuous, at times periodic in acute attacks. The black expectoration which may last six years after the avocation is changed is sometimes of the character of bloody mucus. In description of the third stage, finally, both authors agree; it is the stage of consumption—phthisis anthracotica—differing only in its manifestations from the symptoms of the second stage by their greater intensity. This division into three stages or grades, on more thorough investigation, seems neither necessary nor practicably justifiable, as very frequently cases present which defy all classification, since the disease, in the first place, may be present in high degree and yet run its course without any symptoms whatever, or, in the second place, symptoms may present in entirely different sequence as the authors mentioned have por- trayed. It is best then to disregard the disvision into various stages, at least, to be familiar with the fact that we can by no means succeed in all cases in diagnosti- cating anthracosis from the symptoms during life since with the exception of the characteristic sputa mentioned they are common to many other affections which have nothing to do with this disease. It is only when this black sputa persists, when emphysema of high degree, heart disease and chronic tuberculosis manifest either as sequelae or complications “when all these symptoms bear with anthracosis a common stamp” that the diag- nosis is almost certain. The pulse, then, is quickened, cough is severe, the skin is dry, appetite is gone, diges- tion feeble, urine scant and general strength sinks rapidly to the most extreme marasmus. Physical ex- amination of the chest, then towards the end of the disease, reveals often caverns in the lungs but earlier in its course there is nothing specific observed that may render diagnosis sure. While we must confess that the affection in question presents us but little that is really characteristic in life, the pathologico-anotomical condition observed after * Wide Schmidt's Jahrbücher, W. 124, p. 149, 1864. #Schmidt's Jahrbücher, W. 126, p. 98, 1865. *Seltman, Die Anthracosis der Lungen, etc. Archiv. f. Klin. Med. Vol. II. p. 300, FEB. 24, 1872.] death is markedly characteristic and establishes the dis- ease in most cases at the first glance. In the beginning the minute coal particles are seen as disseminated black points in the alveolae and parenchyma; soon, now, larger masses are accumulated to form black figures of different variety. On the surface these spots seem tolerably equally distributed; they are neither thicker nor more abundant in the upper lobe. The pleura pre- sents a marbled appearance, it is at first smooth, later thicker and adherent in its two layers. In its further course whole sections of the parenchyma are changed into a black mass and in place of the former spots upon the surface there are black hard nodules of the size of a barley grain consisting of minute particles. Finally the tissue becomes a uniform black mass, containing a dark frothy fluid which stains substances in contact with it with a dark color. No trace of normal struc- ture now remains. Nodules of the size of cherry seed are deposited more especially in the middle and lower lobes. Lecanu, Grassi, Magendie and others found in these nodules vegetable coal with 18.4 per cent. ashes. As a rule, caverns are but seldom encountered, their origin, when present, is most probably from an ulcera- tion of the bronchial mucous membrane. This ulcera- tion, as we have already exhibited in the study of bronchiectasis, is by no means rare. It is only ob- served, however, in old miners that have worked for years in an atmosphere charged with coal dust ; such only are the cases which present the perfect picture of anthracosis. Varying in size and number these ulcera- tions are encountered in the upper as well as in the lower lobes at the periphery as well as towards the centre. Their usually uneven, seldom smooth, walls en- close dark colored pus. The bronchi contain also isolated coal particles but no spots such as are observed in the parenchyma. The bronchial glands in graver cases are enlarged and degenerated, and contain particles of coal. The coal nature of these particles is proven by the fact they are not attacked by concentrated acids and alkalies. They burn with a brignt, illuminating flame, on the platinum plate and are found almost perfectly free (Seltmann), very seldom enclosed in epithelial cells. We shall have opportunity again to show that this condition on autopsy is found in all cases of pneu- monoconiosis when we shall again call attention to its significance. Concerning the etiology of this affection there re- mains now not little to be said. It has but one cause and that is a long continued more or less abundant in- halation of the dust of coal. All circumstances which favor the abundant development of this variety of dust and favor its inhalation into the organs of respiration— dry rooms and chambers in manufactories, defective or no ventilation—favor also the production of this dis- † According to Dressler, loc. cit, the pigment of the bronchial glands is perfectly identical with vegetable coal. It is also of a deep black color and is insoluble in alkalies, acids, alcohol, ether and chloroform. T E-ITED CT I I INT I C - 93 ease in every individual long exposed. In the com- mencement of the disease an existing catarrh of the respiratory organs or even a great disposition thereto accelerates in marked degree the development of this disease which in prognosis is without exception un- favorable. Favorable circumstances may unquestion- ably so delay the end that the patient may still, con- sidering the gravity of the affection, attain to an age comparatively advanced. There is of course no special therapy for such an affection. We possess no means of removing firmly fixed foreign bodies from the substance of the lungs. The skill of the physician therefore is limited to a purely symptomatic treatment which is too well known to require mention here. If it be true anywhere, cer- tainly it is true here, as in all diseases caused by the inhalation of the various dusts, that it is much easier to prevent such affections than to cure them. [To be Continued.] –sº-º-º- SCIENTIFIC NOTES. On The Diagnosis of Syphilis by the Microscope. Dr. Lostorfer thinks that the negative results of blood investigation have been due to two causes, namely—1. Hitherto nearly all researches have been made with too low powers; he is convinced that such investigations cannot be made with a less magnifying power than with Hartnack's eyepiece No. 3, and the immersion-lens No. 10. 2. All researches have been made with fresh blood, and the objects soon spoiled by an unfavorable method of preservation. The opinion has, unfortun- ately, always been prevalent, that what is to be seen in blood must be seen best in fresh blood, but it has been overlooked that things may be so minute as not to be viewed at first, but that they may grow to a visible size. Under these considerations, Dr. Lostorfer commenced his researches in August, 1871, in Professor Zeissl's wards for syphilis. The method observed was excess- ively simple. A small drop of blood, taken from a syphilitic patient, was put as quickly as possible on a clean object-glass, covered, the whole object conveyed to an exsiccatorium, arranged in a kind of Recklinghau- sen's moist camera, and daily carefully examined with the magnifying powers mentioned above. The result of the first four objects was already positive, and re- mained so afterwards in large numbers of objects, the blood having been taken from different patients suffer- ing from various, yet unmistakable, forms of syphilis. During the first two days of investigation nothing could be seen except vibriones, bacteria, and commen- cing forms of Sarcina. In the third or fourth day, how- ever, and, in exceptional cases, after the lapse of twenty- four hours, minute bright corpuscles became visible, some of which remained immovable whilst others con- 94 [FEB. 24, 1872. TIEH FL, C T , T N T C. tinued in a state of undulation. Some of these bodies exhibited a projection. On the fourth day (exception- ally on the third, fifth, or sixth day) the corpuscles were enlarged in bulk and in numbers. Of those en- larged, the majority had the projections just named, which were undoubtedly a kind of sprouts, which in some cases were larger in size than the corpuscle itself. In the following days the growing continued, so that some of these bodies became as big as, and even bigger than, red blood-corpuscles. Besides these, there were numbers of smaller corpuscles visible, growing and sprouting, some exhibiting one projection, others three or more projections; the latter were sessile, or had a minute pedicle. The corpuscles were by no means all globular, but of different irregular shapes. After eight or ten days a vacuola was formed in the larger corpus- cles, which extended over the whole corpuscle, and terminated the further development of the growth, Different fluids, as sugar, Pasteur’s liquid, common Salt, acetic acid, etc., were not able to arrest the shrivelling of the bodies and further retrograde development. Concerning the number of corpuscles, it varies greatly in difierent cases. Whether this be dependent upon the different stage of the disease, cannot yet be said, and must be reserved for further investigation. Dr. Lostor- fer has treated in a similar manner the blood of patients laboring under gonorrhoea, diphtheria, eczema, typhus, elephantiasis, and lupus, but never found anything to be compared with the appearance of syphilitic blood. Dr. Lostorfer is cautious enough not to give any opinion as to the relation of the “syphilis-corpuscles,” as he calls them, to the disease; whether they be the cause or the result of the latter he pretends not to know, but contents himself to state the facts he has found. After having alluded to a number of patients (and their histories) from whom he had procured blood for examination, he winds up with the statement that he is able in any case to form the diagnosis of syphilis by ex- amining the blood microscopically. After the paper was read, and received with great applause and encomiums by Skoda and Hebra, Professor Stricker confirmed, in addition, that the author of the paper has been tried seven times—viz., five times by Stricker, and twice by Hebra—in the following man- ner: In the first trial, twelve objects, numbered and registered, were given to Dr. Lostorfer; two (Nos. 8 and 9) were taken from healthy persons, the other ten from three patients suffering from different forms of syphilis. After a few days, Dr. Lostorfer responded:—“Nos. 8 and 9 healthy, two objects spoiled, the rest syphilitic.” Second trial, made with seven objects—“Nos. 3, 5, and 8 syphilitic, the rest healthy.” In both trials, after four days the healthy objects were picked out from the syph- ilitic ones, with the exception of the two objects which were spoiled. Fourth trial, with twelve objects—four syphilitic, and eight healthy. (The objects by some accident having been exposed to a temperature of 12-15°C., previous to their deliverance to Dr. Lostorfer, the latter replied that “Nothing abnormal could be de- tected.”) Fifth trial, with four healthy and three syph- ilitic objects. The reply was corresponding to the registration made by Professor Hebra and kept by himself secretly. In the sixth trial, one syphilitic object was given, and five healthy; in the seventh, two syphilitic and four healthy; and in both cases recognised accor- dingly.—Lond. Med. Gaz., Jan. 27, '72. SARCINA IN BLOOD.—Dr. Ferrier of King's College, London, calls attention to a curious fact which he has just discovered, of great importance in reference to the much-discussed subject of disease-germs. He states that the peculiar microscopic organism, the Sarcina ventriculi, which has hitherto been found almost exclusively in diseased conditions of the stomach, exists in an unde- veloped state constantly in the blood of the lower ani- mals and in human blood, both in health and disease. Dr. Ferrier further states that the minute particles which are constantly found in vaccine lymph, and which have been supposed to be the active agents of the vaccine virus, are nothing more than undeveloped sarcinae.—Brit. Med. Journ., Jan. 27, '72. ——º-e—sº- MEDICAL NEws. A CURIOUS SUGGESTION.—Sir Dominic Corrigan has proposed, in a letter to the Dublin papers, that patients suffering under small-pox should be conveyed through the streets of that city on shallow baskets or cots six feet long, resting on poles on men's shoulders. “No suggestion,” says the Irish Times, “was ever made so well calculated to drive from the city of Dublin every- one who could leave it. QUACKS SHUT OUT FROM PENN. HoSPITAL.-The announcement of the Eclectic Medical College, in addi- tion to setting forth the great advantage which it offers to its students, says that these have access to the clin- ical lectures delivered at the Pennsylvania Hospital. This, we are glad to be able to say, is no longer true. The Managers of the Hospital have given the members of the medical and surgical staff the power to exclude the students of any medical institution that they may please, and acting under their directions, the Steward of the Hospital has declined to issue tickets to students of the Eclectic Medical College. This action on the part of the staff has called forth a note from the Dean, who must be a gentleman of most refreshing coolness. The note is as follows: “DEAR SIR:—You have intimated to our students that they cannot attend the Pennsylvania Hospital,—a state institution, which we aid in supporting. Before applying to the court for a mandamus, I merely desire to know if you persist in their exclusion. Please inform bearer. “Very respectfully, JosLPH SITES, Dean.” The only reply made by the Steward to this threaten- FEB. 24, 1872.] T THIIH, C T , ITNT I C . 95 ing epistle was that Dr. Sites was correctly informed; and up to this time no legal measures have been taker, so far as we are aware, to force the hospital to open its gates to the doctor's protégés. The Pennsylvania Hos- pital is not a public institution, but is supported entirely by voluntary contributions; but, even taking the view of it that Dr. Sites does, we cannot imagine how the Eclectic Medical College can possibly aid in its support, or in the support of any of the public institutions of the city; and the note is simply a piece of bravado, and was so regarded by the gentleman to whom it was addressed. It has been usual to grant certificates of attendance to all students who have taken the Hospital ticket; but, as there is evidence that these certificates have been made to serve for diplomas, the staff has determined to issue them only to the students of the regular colleges. —Phil. Times, Feb. 15, 272. THE following review is just as good as if it had origi- nated in the pages of THE CLINIC : A CONTRIBUTION TO THE TREATMENT OF VERSIONS AND FLEXIONS OF THE UNIMPREGNATED UTERUS. By EPH. CUTTER, A. M., M. D. Pamphlet, 8vo, pp. 44. Boston, James Campbell & Co., 1871.-Another effort towards a more successful treatment of uterine displace- ments. Dr. Cutter brings forward two pessaries, one of which he describes as “purely his own.” Both act as bent levers, the anterior edge of the perineum being the fulcrum, the cervix the point to be held or moved, while to the short external arm, force is applied by a band of india-rubber tubing, passing backwards between the nates and upwards to a waist-band. In their adjust- ment we are introduced to a new family of uterine in- struments, loop- and T-pessaries, vaginometer, vaginal sounds, perineal elastic bands, defecating attachment and joint—we become bewildered at the fertility of mechanical ingenuity. Amid the maze, some, doubt- less simple, points still preplex us. In regard to the short arm, we read, p. 13, “The perineal hook should surround the perineum without touching it,”—seem- ingly a difficult task for the hook; and how, we ask, are we to discover “if air does not circulate between it and the perineum” 7 Again, both elastic tube and hook are directly in the way of defecation. P. 13, “Patients should be instructed to loosen the belt about two inches before defecation, then turn the hook forwards and hold.” Fancy the agony of one seized with imperative intestinal premoni- tions, striving in vain at the last moment to remember the lucid directions, “loosen the belt about two inches before defecation,” etc. . Why about two inches before defecation, when another instrument might be so readily devised to measure it more accurately 2 On p. 15 we are told that should subsequent discom- fort arise there must be something wrong, either with the patient or pessary; and we learn that iodoform sup- positories are useful in allaying vaginal irritation before or after using this pessary, which doubtless possesses some subtile influence over that refractory drug which other pessaries do not. How truly and graphically could a grateful patient describe herself, after being relieved, as right to a Tl On page 31 the author shows how he often persuades unwilling patients to be bled: he tells them, “Water is indispensable to human life. If people fall into the water, and life is destroyed, is this an argument against its use as a beverage?” This is unanswerable, and al- most equal in clearness and simplicity to his “homely illustration” a few pages before: “Suppose you have a uterus in your coat-sleeve.” Excuse us; we had rather not. w We get on page 41 a chance insight into the personal habits of the author. What a simple, honest taste is expressed in the words, “I say lard, because I like it better than anything else.” I Better even than obstetric surgery, doctor? - We are advised that vaginal examinations be made upon a “dining-table.” Why, we ask, on a dining-table 7 True, he explains somewhat later, “because they [the patients] do not sink in.” Does ‘anybody suppose they do? We should fancy, however, that after submitting to his mechanical measurements and appliances they might be desirous of doing so, if they could.—Phil. Times, Feb. 15, '72. ——sº- e-º- CORRESPONIDENCE. EDS. CLINIC: GENTLIMEN : In your notice of the bandaging con- test, inaugurated by Prof. Dawson, at the Good Samari- tan Hospital, it is intimated that the jury convened for the occasion, were unable to decide between five of the eleven contestants, and consequently that the prize had to be awarded by drawing lots. I desire to correct this statement. The fact is that the students having shown their general proficiency in the arena by using different kinds of bandages and applying them to dissimilar parts of the body, the jury selected from their number, those who had attracted the most attention, and in order that the contest might be fair, confined them to the use of exactly similar bandages applied to exactly similar parts. While admiring the adroitness and exactness in bandaging of Messrs. Brown, Lockhart and Lyle, the race from the first appeared to be between Messrs. Black- stone and Plummer and was at length run conjointly, or almost so, by them. After the jury had discussed the respective merits of the two gentlemen, each of the two had a vote cast in his favor. It then rested with the third juryman to award the prize; it was decided that he should draw lots, and the luck fell to Mr. Black- stone whose rapidity and evenness in bandaging made him fully equal to Mr. Plummer, who excelled him in some other particulars. Yours Obediently, - CUNDEL JULER, M. D., M. R. C. S. L. 96 [FEB. 24, 1872. T IEEE IET: C T I I INT I C - CLINICAL MEMORANDA. TURPENTINE IN ACUTE AFFECTIONS OF THE MID- DLE EAR.—Dr. Weber, of Berlin, says he has used Oleum Terebinthinae internally, for two years, in acute and painful affections of the middle ear, and regards it a specific. He prescribes it in every stage of acute otitis media. In order for it to be effective it must be given in pretty large doses; e.g., twice during the day not quite a teaspoonful and in the evening a full one. If it produces nausea and dizziness, as it sometimes does, the doses during the day can be lessened, but not the one for the evening. . Even if the patient has suffered for weeks and been unable to sleep, in most cases sleep will be had on the first might. He regards its efficacy the most striking in acute rheumatic middle ear affections as contrasted with those the result of acute nasal catarrh. In the latter he recommends the inhalation of the steam from camomile tea with the addition of some balsam by which the patient is thrown into a heavy perspiration. Fresh acute otitis can, according to the author, be strangulated by the oil. He uses it even in traumatic middle ear affections, e. g., in tenotomy of the tensor tympani, also as a prophylactic before such an opera- tion.—Monatsschr. f. Ohrenh. [It might be well to state that inflation of the ear is used along with the oil, a proceeding that in itself in a large number of cases of acute middle ear affections is followed by the most marked relief]. SKIN PUNCTURE IN ANASARCA.—When other means fail to prevent the increase of dropsy, the anasarcous fluid may be allowed to escape through incisions or punctures in the legs. The drain of liquid usually affords great temporary relief, and is often followed by a copious Secretion of urine. It is not to be denied— and the patient and his friends should be informed— that incisions or punctures are sometimes followed by inflammation and sloughing of the integuments; but then, on the other hand, distension of the skin by an excessive dropsical accumulation is not unfrequently attended with the same unpleasant results. In my ex- perience, erysipelatous inflammation and sloughing have resulted more frequently from over-distension of the integuments than from punctures made to remove distension. On the whole, then, puncturing anasarcous legs is an operation which, when done with proper pre- cautions, is so advantageous to the patient, that we dare not shrink from the responsibility of advising it. Many instances have come under my observation in which this simple operation has prolonged life in com- parative comfort for a very considerable period.—John- son—Brit. Med. Journ., Jan. 27, 1872. —sº-º-º- IHOMIE NEWS. THE following gentlemen are appointed internes to the City Hospital for the ensuing year:—Jas. H. Brown, W. H. Falls, Jas. G. Hyndman, Ferdinand Kramer, J. L. Neave, B. Rattermann. During the past week the lecture rooms have present- ed a picturesque appearance. Ninety-five students might have been seen at any hour of the day nervously studying the ten questions posted on the board on all the branches of medicine successively. The agony of the week is over. Two days of cloudy anxiety now and then the sunshine of peace forever, Medical College of Ohio. S P R | N G C 0 U R S E , * & The regular eight weeks course of practical instruc- tion for the Spring of 1872 commences March 15. Un- usual advantages are offered this year in the fact that the course will be conducted by the entire Faculty of the College. The course will embrace the following topics: Clinical Medicine—Bartholow. “ Surgery—Dawson. - Anatomy Brain and Nervous System—Gobrecht. Operative Surgery—Conner. {{ Obstetrics—Reamy. & & Ophthalmology—Seely. Female Pelvic Surgery—Palmer. Urinalysis—Nickles. Physical Diagnosis—Cleveland. Fractures and Dislocations—Kearns. Genito-Urin. Dis.—Anderson. Microscropy—Whittaker. Prof. Graham will deliver occasional lectures on Clin- ical Medicine and Diseases of the Chest during the pro gress of the Course. The design of the Course is to present instruction in a thoroughly practical manner. Physical Diagnosis is to be demonstrated in the hospital wards; Operative Surgery, Operative Obstetrics, Operative Ophthalmology, and Operative Gynaecology on the cadaver. - The Dissecting Room will be under the supervisionof Dr. where abundant material will be provided. Special attention will be paid to the chemical and mi- croscopical analysis of morbid urine. In order to render this course the most practical pos- sible, an opportunity will be afforded each individual of the class to make the various examinations and opera- tions on the living and dead subjects. Regular daily Medical and Surgical Clinics will be held at the Good Samaritan Hospital: Two Daily Clinics will be regularly held in the Cincinnati Hospital, throughout the entire course; and a Daily Clinic will be held at the Dispensary of the Medical College of Ohio. One hour each evening will be devoted to Recitations on Anatomy, Physiology, Practice, Surgery, Obstetrics, and Materia Medica. The eminently practical nature of this course, and its shortness of duration, together with the great clinical advantages presented in Cincinnati, can but commend themselves favorably to the practitioner as well as the student. FEES FOR THE ENTIRE Course, $10 As this Course does not count towards graduation, being considered supplemental to the regular winter course, graduates of the College are not required to matriculate. The matriculation of non-graduates is deducted from the fees of the ensuing winter session. F. E. SUIRE. * E. S. WAYNE F. E. Suire & Co., WHOLESALE DBUGGDSTS, M. A. N. U E A CT UER IN G. £Hemists AND FHAR MACEUTISTS, CINCINNATI, OHIO. Have constantly on hand a full assortment of s)ex.):cºexexo ox{UGS ANYO WXYºoxc)(N)es,. cºeryxxcAM. Aexas Aºcus, TESTs, MEDICAL GLASS WARE, &c, &c., And solicits the patronage of the trade and profession- We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, Made in accordance with the U. S. P. and other recognized authori- ties. . FINE AND RAERE CHEMICALs, Of the popular class of preparations known as H. T. IIXIIIR, S, We manufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. . Bitter Wine of Iron, An excellent Chalybeate and tonic, Wine of Iron, &c. AGENTS FOR BULLOCK & CRENSHAW's Sugar-coated Pills and Granules. 3. Price Lists of preparations and of Sugar-coated Pills sent by Mail upon application. The long standing and well and widely known repu- tation of our house we offer as a guarantee for the reliability of our Preparation, and the quality of the goods sold by us generally. ... tº sº. 8 º' - JAMES FOSTER, JR., & CO. Instrument Makers and Practical Opticians, Beg leave to return thanks for the patronage extended to them through a long series of years (having been established since 1836), and in the reorganization of their firm will endeavor to merit a continuation of the same. We wish it understood by the Profession and the Public generally that our invariable rule is, to make or import none but the best in- struments. Those in want of any of the acknowledged good aids of vision to imperfect eyes, will always find the best and largest stock of Lenses, Spectacles, and the best models procurable, with pains- taking skill to adjust them to all conditions of sight, . at our house. Special attention paid to orders for Fine Microscopic Objects and Microscopic Apparatus, Magnifiers and Readers in great variety. Medical Batteries, Barometers, Thermo- meters, Hygrometers, Urinometers and Rain Gauges, of the most approved construction always on hand. All orders promptly and accurately filled. JAS. FOSTER, JR. dealing F. S. SHACKLEFORD, : *** * JAS. FostER, JR. & Co. S. W. Cor. Fifth & Race Sts., Cincinnati, 0. TIER, S.INT.INMA ERSEHI’s - No. 758 BRoapw AY, New York I HAVE been in the habit of applying and recommending the Truss manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. . As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined. LEWIS A. SAY RE, M. D. Surgeon, Bellevue Hospital. From Prof. Willard Parker to S. D. Townsend, M. D., Surgeon to the Massachusetts General Hospital. BEG leave to state for the benefit of all concerned, that I have known Dr. S. N. Marsh the last fifteen years. * * * I am in the constant habit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with anv of the risks to the patient that exist in many of the plans suggested and attempted to be carried into execution. I have confidence in Dr. Marsh as a gentleman of honor and integrity, and as such recommend him to the members of the medi- cal profession generally. WILLARD PARKER, M. 1). - Professor of Surgery, New York City Dr. S. N. Marsh's Patent Radical Cure Truss, and all other kinds of Trusses, Shoulder Braces, Supporters, Elastic Stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Cure Truss Offices of S. N. MARSH & CO., No. 2 Wesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. OPPOSITE THE HIGH STEEPLE. JW2, Ž% WºSA," Fovara. Szºnºr, - PIKE's OPERA HOUSE BUILDING, / ealer In porter and Diamond and Gold Jewelry, watches for Ladies and Gentlemen, Sterling Silver Tableware, Bronzes, Antique and Modern; Marble and Bronze Clocks, . Marble statuary, . FAN cºr Co O DS, G ENER ALLY. 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A gents at Circleville, O., reports 25 orders in 2 days; one at Louisville, Ky., reports J75 orders in 8 days; one at Middletown, Conn., reports 200 orders in 12 days; one at Cincinnati, O., re- ports 250 in 12 days. Early applicants secure choice of territory. For circulars, terms, &c., address NETTLETON & CO., I61 Elm Street, Cincinnati, O. BASCOM & CARPENTER, Stationers, Printers ---, --, Sºz -AND-- . Blank Book Manufacturers, 136 VINE sº IREET, " &\\\\\\\\\\\e E. De ALBRO & BRO. IMPORTERS JAND MANU FACTURERS OF FOREIGN and DOMESTIC WOODS In Veneers, Boards and Plank, fºr ſaint-Maºri', 'it-Bºilèſ'ari Stair-Blileº'º. Pike's opern-House, Fourth Street, Cinefnmati; 931 Wabash Avenue, and SS West Washington * street, Chicago. - - ** -> * * * : * > . The only house in the Western country that saws Spanish and Mexi- can Cedar for Cigar-Box Makers We import our owu wood direct, and can sell at prices to compete with any and everybody. Also saw a tid keen on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. office and Warerooms, 136 and 138 West Second Street, Wenyer Mill, 507, 509, 541, 513 & 515 W. Sixth St., CINCINNATI, £:32:3:... -- --- º §s # iſºlº º †† #| ||iſº º: |f||{{# ºft||| §§2.5ºE.; —#|ſſiſſiliº #; §§§ Sºś * * *** --- initiº . . . . . º.º.º. ~ º H. - 2 º' º º §§ | º º #|| ſ § - $2:S º : : º il'ſ | | zº: * Sºft §§§sº § flºº | #: § É #|#####|# É ######## ſº ####|º É. º * É fºliº; † - ºr 2: Fºsº º: 2:S25 j | # * # #### 3:25 ºf flºº. § #. % :=#####sº §. arº - 2. º: * & - ºfºº % % º: # º' -º-º: % ºzzº - §: ##$$.” -j - É -º-º-º: % % ſº #4 # ######## #7% % º r ØØ; ÉÉ4% ºãº ‘E exº---> E.; 2%% º ===== - 22º Aſ % % - --~~~~ -º- zzzº- %% GooD sAMARITAN HOSPITAT. The GOOD SAMARITAN HOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner of sixth and Lock streets. It is handsomely furnished through9% and is provided with all the necessary ap- pointments of a First-class Hospital. Porticoes, with commanding views, surround the whole house, and wide halls and abundant windows secure that full and free ventilation which is so essential to health and comfort. Service is furnished by the SISTERS OF CHARITY, Under the Superintendence of the well-known SISTER ANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. The regular Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each Professor presiding over his own especial department. Patients may, however, select from the regular profession of the city any physician of their choice. The GOOD SAMARITAN HOSPITAL presents extra inducements to quiet asylum in any some stay is necessary in after treatment. Rooms vary in price, general terms, between $3.00 and $15.00 per week. This includes, of course, Bºy" Address, SISTEER ANTHONY, Invalids throughout the State as a safe and case of protracted illness, or in cases, more particularly, requiring Surgical Operation, where according to the character of appointments necessary and service required, ranging, iº the diet list, and every demand of º: FIospital of the Good Samaritan, Corner of Siacth and Lock Sts., Cincinnati. Ohio- ||NF||RTS, Carriage Manufacturer, Nº. 9 and Il Fast Sixth Street, bet. Main & Sycamore. I MAKE NOTHING BUT Jº ZºS 7" CºA ºf S.S. W’0/*A*, Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of LIGHT FAMILY CAFFIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- ... tensive variety of light elegant designs of different cost and finish. In vehicles especially adapted to PHYSECHANS” {jSE, The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. The superiority of my light gentlemen's g:=s --- fºº::=ºs ea ººs - wº- . . . . . . tº buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price lists furnished on application. References to Dr. W. W. Dawson and all the leading Physicians in the city and neighborhood. : º żºłºś tº §§ º 5.3 -.* i º: | º:º. ||º- º*- rt-S. º=-. i. i º- º-- º | . | ºMº---------- ººi.R |i :º; ! f ;i| jR:| %º º|º §w *Nº & ºº ſ º:º CINCINN ATI. e-º-5-3- —-º- --~~~~ IF. A. C. LJ I, T Y . J A M E S G R A H A M, M. D., D E A N, Professor of the Theory and Practice of Medicine and Clinical Medicine. ROBERTS BARTHOLOW, M.D., Professor of Materia Medica and Therapeutics. W. H. GOBRECHT, M.D., Professor of Anatomy. P. S. CONNER, M.D., Professor of Surgical Anatomy. W. W. SEELY, M.D., Professor of Diseases of the Eye and Ear. SAMUEL NICKLY'S, M.D., Professor of Physics and Medical Chemistry. J. A. VI E S T * . W. W. DAWSON, M.D., Professor of Principles and Practice of Surgery and Clinical Surgery C. D. PALMER, M.D., Professor of Medical and Surgical Diseases of Women. T. A. REAMY, M.D., Professor of Obstetrics and Diseases of Children. JOHN L. CLEVELAND, M.D., Demonstrator of Anatomy. CHARLES KEARNS, M.D., Assistant to the Chair of Surgery. W H ITT A. Ex E. F. , Professor of Physiology and Secretary of the Faculty. ,--~~~~ T. LOUIS BRown, Prosector of , ! watomy. Janitor, College Building, Sixth St., bel. Vine and Race. Printed and Published by Noahrº & MURRY, Medical College of Ohio Building, Cincinnati, THE CLINI C. PTſIELISHED EVERY SATURDAY. T E R M S-$2.00° a Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editor: All Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer. Vol. 2. C IN C IN N A TI, Tºº M A R C H 2, 1872. No. 9. JAS. T. VVHITTAKER, M. D. No. 101 West Ninth Street, Cincinnati. _ASSOCIALTE EIDIETO-E,S. W. W. Dawson, M. D. THAD. A. REAMY, M. D. P. S. ConneR, M. D. C. D. PALMER, M. D. W. W. SEELY, M. D. SAMUEL. NICKLEs, M. D. CHAs. KEARNs, M. D. JNo. L. CLEvKLAND, M. D. RoRERTs BARTHolow, M. D. W. W. SEELY, M. D., No. 118 West Seventh Street, Cincinnati. -> º - Editor. TREASURER. C L U B R A TES, *-*s 4 Copies to one address.-----................................................ $ 7.00 6 & © 44. * 10,00 12 4 & & £ 18.00 C O N T E N T S. *-*- Page.] ORIGINAL AIRTICLES Purulent and Gonorrheal Conjunctivitis, by W. W. Seely, M.D........97 .** * A. - ºr ºr * ~~ * * * A Windication of the Hydrate of Chloral, by C. W. Cram, M, D.......... 98 TRANSTLATION Coal Dust in the Lungs, (A Chapter from Hirt's Staub-Inhalations Krankheiten, Breslau, 1871.) I02 SCIENTIFIC NOTES Recent Progressin Chemistry—The Painless Destruction of Animal Life ..... NIELD ICAI, NEWS Loyalty to Science—Statistics of the Race CORRESPONDENCE Letter from Dr. Trush, Vienna—A Case of Extra-Uterine Preg- nancy * 105 CLINICAL MEMORANIDA Sick Head-ache 107 Questions of the Examination..... 107 RIOME NEWS 108 THE CLINIC of this week-continues the exceedingly interesting series of articles on coal dust inhalation. The series will be concluded in the next number. It is a matter of regret that the translation on cancroid, etc., is unavoidably crowded over. In its place is presented, in a letter from our Vienna correspondent, a detailed account of a remarkable case of extra-uterine foetation. By request of a number of the students the questions of the examination are inserted in this number. co-Ary tº ce. Fashionable Hatters, IMPORTERS AND MANUFACTURERs of 92 WEST ENOTTERTIEH ST. Opposite Post Office, CINCININATI. sºrspecial Inducements to Medical Men. §§AN ºbesicNºs Alº … . . . . . . . 2, sº gº º A *...* 2:... . ºf . ---- ºr , -, -- " . = re^Sººt & 2. WES 77 FC JR. H. Sº º-º-º- SºciNCINNATI, ofilo. É. - J. TAFT, Editor Dental Fregister J. & W. TAFT, TXTEINTTISTS 117 WEST FOURTH STREET, W. TAFT. CINCIN NATI, O. A MOnthly Journal, CONTAINING 48 PAGES, Devoted to the Interests of the Dental Profession, O ID O ER, IL E S S A. IN ID PA. L. A. T. A. B. L. E . In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERs & BARTLETT, of Portsmouth, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. Our motice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. sº Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachitic Affections, in Chronic Rheumatism, &c. The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. William Autenrieth, No. 71 WEst, sIXTH strºBET, CINCINNATI, OHIO, MANUEACTURER OF AND DEALER IN || || || || || Abdominal Supporters, Trusses, GLUB-F00T SHOES, Keeps constantly on hand a full variety of Metaſic and Eubber syringes, Storm.ach Pumps, Etc. STOCKINGS FOR WAR}}(GOSE WEBNS, Special attention given to the fitting of Apparatus for Deformities. gº Agent for DR. L. A. BABCOCK'S tsilver Uterine Supporter, DR. AHL's POROUS FELT SPLINTS, D A. Y. * S S E LIN TS S. W. BETWEEN WALWUT Aib WIME, J 5. illiott’s Saddle-bags SPINAL APPARATUS, ETC -ALSO– —ALSO– -AND- ROBERT CLARKE & Gū’S. LIST OF NEW Mill, iTH in Mºulis Hill; GREEN'S PATHOLOGY AND MORBID ANATO MY, 8vo. Cloth. $2 5c - DUCHENNE'S LOCALIZED ELECTRIZATION. 8vo. $3 oo DILLEN BERGER ON WOMEN AND CHILDREN’S DIS- EASES. 12mo. $1 75 BENNETT ON PULMonoRY CONSUMPTION. 8vo. $1 5o FIRST HELP IN ACCIDENTS. 12mo. $1 50 BEASLEY'S DRUGGIST RECEIPT BOOK. 8vo. $3 50 ECHEVERRIA ON EPILEPSY. 8vo. Cloth. $5 od HOWE ON EMERGENCIES. 8vo. $3 oo HAMMOND ON NERVOUS DISEASES. 8vo. $5 od RINDFLEISCH'S PATHOLOGICAL HISTOLOGY. $6 oo WARINGS’ PRACTICAL THERAPEUTICS, 2nd Am. Ed. 8vo. Cloth. $5 oc Leather. $6 oo SCUDDER'S SPECIFIC MEDICATION. 12mo. Cloth. $2 50 TANNER'S HANDBOOK OE OBSTETRICS. I 2 mo. $2 oo WAN BUREN ON DISEASES OF THE RECTUM. 12mo. Cloth. $1 5o FLINT'S EXAMINATION OF URINE. 12mo. Cloth. $1 oo VOGEL ON DISEASES OF CHILDREN. 8vo. Cloth. $4 50 BEARD AND ROCKWELL’S MEDICAL AND SURGICAL ECECTRICITY. 8vo. Cloth. $4 50 ATTFIELD'S MEDICAL CHEMISTRY. 12mo. Cloth. $2.75 Leather. $3 25 BARTHOLOW’S HYPODERMIC MEDICATION. I 2 mo. Cloth. $1 5o TURNBULL’S DISEASES OF THE EAR. 8vo. Cloth. $5 oc TILT'S CHANGE OF LIFE. 8vo. Cloth. $5 oc NEUMANN'S HAND-BOOK OF SKIN DISEASES. 8vo. Cloth. $4 oo ANSTIE ON NEURALGIA. 8vo. Cloth. $3 oo. PANCOAST'S OPERATIVE SURGERY. 4to., with many plates. $1 o oo HOOD ON BONE SETTING. Izmo. $1 5o RINGER'S HAND-BOOK OF THERAPEUTICS. 8vo. $4 oo HOLBROOK’S PARTURITION WITHOUT PAIN. I. 6mo. $1 oo PROCTER'S LIGHT SCIENCE FOR LEISURE HOURS. 12mo. $1 75 BERNARD’S PHYSIOLOGY OF THE HEART: 50 cts. BARNES’ OBSTETRICAL OPERATIONS. 8vo. $4 50 NICHOL’S FIRESIDE SCIENCE. 12mo. $1 50. WOHLER'S MINERAL ANALYSIS. 12mo. Cloth. $3 oo PLATTNER'S MANUAL OF ANALYSIS WITH THE BLOWPIPE. 8vo. Cloth. $7 50 JEFFRIES ON THE EYE. 8vo. Cloth. $1 oo MANSFIELD, A THEORY OF SALTS. 8vo. Cloth. $4 oo JEFFRIES ON THE SKIN. 8vo. Cloth. $1 oo GARDENING FOR PROFIT. 12mo. Cloth. $1 50 PRACTICAL FLORICULTURE. 12mo. Cloth. $1 5o FULLER'S SMALL FRUIT CULTURE. 12mo. Cloth. $1 50 WOODWARD'S COUNTRY HOMES. 12mo. Cloth. $1 50 DARWIN'S ORIGIN OF SPECIES. 12mo. Cloth. $2 oo ARTHUR'S TREATMENT AND PREVENTION OF DE- CAY OF THE TEETH. 12mo. $1 50 TYNDALL ON LIGHT AND ELECTRICITY. 12mo. $1 25 THE AMATEUR MICROSCOPIST. Small 4to. $1 75 BOOKS IN PREPARATION. BRYANT'S PRACTICE OF SURGERY. BARNES ON DISEASES OF WOMEN. ROBERTS ON RENAL DISEASES. GUERSANT, SURGICAL DISEASES OF WOMEN AND CHILDREN. Medical, Scientific, and other Catologues sent on application. Any book in the above list sent by mail or express, free of charge on receipt of price. 65 West 4th Street, Cincinnati, Ohio. List of Pharmaceutical Preparations, MANU FACTURE O BY Jø/ZW WWZZZZ & ZºoZººZºº, FELLIADFELFECIA. —-º- ELIX. PHOS IRON, QUININE AND STRYCHNIA, ELIXIR OF GENTIAN FERRATED, ELIXIR, WALERIANATE OF AMMONIA, /* (Goddard's Formuła,) ELIXIR VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, Krom, with Phosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Kron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK, ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER WINE OF IRON, Citrate of Hron and Peruvian Bark, FERRATED CORDIAL ELIXIR, ELIXIR, CALISAYA BARK, WINE AND BISMUTH, ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMIUTH, TASTELESS COD LIVER OIL, TASTELESS COD LIVER OIL. FERRATED, BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and sherry wine, ELIXIR WALERIANATE OF STRYCHNIA, WINE OF PEPSIN SYRUP SUPERPHOSPHATE OF IRON. y ELIXIR OF BISMUTH, COMP. FLUIDEXT. BUCHU AND PAREIRA BRAWA. SUIPEPOSITOTER, TIES. Rectum, Vaginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great eare, and of every variety of combination. Lists sent on application. SPONGE TENTS.—For the Urethra, of every size and style, made of finest quality of sponge. & Instrument Makers and Practical Opticians, Beg leave to return thanks for the patronage extended to them through a long series of years (having been established since 1836), and in the reorganization of their firm will endeavor to merit a continuation of the game. We wish it understood by the Profession and the Public generally that our invariable rule is, to make or import none but the best in- struments. Those in want of any of the acknowledged good aids of vision to imperfect eyes, will always find the best and largest stock of Lenses, Spectacles, and the best models procurable, with pains- taking skill to adjust them to all conditions of sight, at our house. ' Special attention paid to orders for Fine Microscopic Objects and Microscopic *::::::: Magnifiers and Readers in great varietv. edical Batteries, Barometers, Thermo- meters, Hygrometers, Urinometers and Rain Gauges, of the mºst approved constraction always on hand. All orders promptly and accurately filled. - - JAS. FOSTER, JR. F. S. SHACKLEFORD, : **ing * * As. Foster, Jr. & co. S. W. Cor. Fifth & Race Sts., Cincinnati, O. TIER,.S.INT-TMCA R.S.H.’s - & de No. 758 BROADWAY, NEW YORR HAVE been in the habit of applying and recommending the Truss manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined. LEWIS A. SAYRE, M. D. Surgeon, Bellevue Hospital. From Prof. Willard Parker to S. D. Townsend, M. D., Surgeon to the Massachusetts General Hospital. B EG leave to state for the benefit of all concerned, that I have known Dr. S. N. Marsh the last fifteen years. * * * I am in the constant habit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with any of the risks to the patient that exist in many of the plans suggested and attempted to be carried into execution. I have confidence in Dr. Marsh as a gentleman of honor and integrity, and as such recommend him to the members of the medi- cal profession generally. WILLARD PARKER, M. D. Professor of Surgery, New York City amammammammº Dr. S. N. Marsh's Patent Radical Cure Truss, and all other kinds of Trusses, Shoulder Braces, Supporters, Elastic Stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all | other Physical Deformities, made and accurately fitted at the Radical Cure Truss Offices of S. N. MARSH & CO., No. 2 Wesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. OPPOSITE THE HIGH STEEPLE, F. E. SUIRz. E. S. WAYNE IT. T.C. Suire & Co., WHOLESALE DRUGGUST’S, IM. A. N. U E A C T TJ IF, T INT GF £Hemists AND RHARMAceutists, CINCINNATI, OHIO. Have constantly on hand a full assortment of sye), ecºexex) ox{UGS ANYO ſwk)ex}}(c)(N)es, c)HOEIVO(CA), Aº’A}{A^0 US, TESTS, MEDICAL, GLASS WARE, &c., &o., And solicits the patronage of the trade and profession. We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, lºade in accord ºnce with the U. S. P. and other recognized authori- ties. E"IN JH AND R.A.F.E CHEMICALS, Of the popular class of preparations known as E T, IL&T I IF, S, We manufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. Bitter Wine of Iron, An excellent Chalybeate and tonic, Wine of Iron, &c. AGENTS FOR BULLOCK & CRENSHAW'S Sugar-coated Pills and Granules. Price Lists of preparations and of Sugar-coated Pills sent by Mail upon application. The long standing and well and widely known repu- :ation of our house we offer as a guarantee for the reliability of our preparation, and the quality of the goods sold by us generally. -msº ----- Wm. Wilson McG wo. 27 west rowarm screer, PIKE's OPERA HOUSE BUILDING, Importer and Dealer —--~~zee I N eeeee- Diamond and Gold Jewelry, g .. Watches for Ladies and Gentlemen, - . Sterling Silver Tableware, 3. Bronzes, Antique and Modern; Marble and Bronze Clocks, - Marble statuary, FAN. cx Coops, G E N E R A L L Y. . T H E CI, IISTI c. 97 vol. 2.) S A T U R D A Y, M A R C H 2, 1872. [No. 9. O R. I.G IN A L A R T H C L E S. —---— PURULENT AND GONORE HEAL CONJUNCTIVITHS. + BY PROF. SEELY. A Clinical Lecture at the Dispensary of the Medical College of Ohio. I am unable to tell you, gentlemen, why as the re- sult of a given cause we find in our case one form of inflammation and in another case some other form. I present you to-day with two cases of inflammation of the conjunctiva, attended with a purulent discharge. The first case, as you see, presents all the symptoms of a violent inflammation, viz., great swelling of the lids, which are hot and Oedematous, the eyelashes matted together, great chemosis of the bulbous conjunc- tiva and an abundant purulent discharge. On questioning the patient we make out no infection by gonorrheal matter, but find that he has had weak eyes for sometime and that, being very much exposed, the eyes suddenly became greatly swollen, and in a day or two began to discharge freely. While speaking of granulations I told you that a possible termination to such a condition might in the appearance of all the symptoms be presented here. I also remarked that the manner in which granulations disap- peared was through absorption, and hence a certain amount of inflammation was necessary to rid the con- junctiva of the new growths. I also spoke of the process of getting rid of these bodies—the so-called inoculation method. I have also shown you how moist warmth may be applied to bring about a similar state of things. If my diagnosis is correct we have here a purulent in- flammatory process engrafted upon the trachoma. Everything seems to point in that direction. When we evert the lids we are unable to see any granulations it is true, because the papillae are enormously enlarged, and yet when you have seen a few cases of trachomatous conjunctiva convérted into the purulent and of the papillated the result of purulent primary inflammation you will be able to see that something which I think indicates a difference. - (* Here, as is usual, we have the statement that the eyes had been weak for some time. & - While speaking of this possible termination of granu- lations, I specially called your attention to the points in the therapeutical management, for in this resides the chief interest. In these conjunctival inflammations the danger is in complications on the part of the cornea. posed in part of calomel. Let us look then for a few moments at the points in treatment. In this country we see but seldom that terrible inflammation that attacks the conjunctiva, the diphtheritic, characterized by extreme hardness of the lid, due to a fibrinous exudation into the conjunctiva and sub-conjunctival tissue, bulbous as well as palpebral, that may bring about destruction of the cornea in some cases in 36 hours. - However, we not infrequently do see symptoms which indicate that we are in the presence of more or less stasis in the circulation. In the stage of inflammation and swelling that im- mediately precedes the purulent, in purulent conjunc- tivitis then, the point is to beware of the use of astring- ents, in fact I may say that is the safe general rule that cannot be insisted upon too strongly. In this stage your reliance must be upon a general and local anti- phlogistic treatment. A brisk purgative or two, com- Opium for the relief of pain. - Quiet in bed with the room moderately darkened. Locally, if the patient is in a physical condition that justifies it, blood-letting by leeches or cups. If the lids are greatly swollen a lengthening of the commissure by slitting the external angle, which of itself may let out the necessary amount of blood. - As a wash, the Sulphate of Atropia. (gr. jv. ad. 3.j). I say nothing of the application of cold as it requires such great care to be followed by beneficial results. After the purulent stage begins, indicated by the ap- pearance of pus, your more active local interference comes in. - The same cautioning at the beginning of this stage applies in this country as well as in Europe, “begin your astringents carefully,” for fear of producing a stasis in the circulation and changing the resolution stage into a violently active one, that gives rise to layers of lymph upon the surface of the conjunctiva, and possible a fibrinous exudation into its substance, As to the therapeutic agents, the one generally recom- mended in all purulent inflammations, is nitrate of silver. Then begin by applying a weak solution of the nitrate, (gr. v. ad. 3.j.) on the appearance of the purulent dis- charge, brushing it upon the everted lids, or on the lower if they cannot be everted on account of the swelling. - If the next day the purulency has increased you can apply a still stronger solution, and neutralize it with salt and water. When the symptoms of acuteness have began after a few days to subside your antiphlo- gistic treatment should be abandoned. For some little time after your brushing with the nitrate you can apply cold compresses to the lids, changing them every minute or two. The atropia and brushings with the nitrate should be continued until the purulent discharge has entirely ceased. - If complications on the part of the cornea arise there 98 [MAR. 2, 1872. T IEI IE C T , I INTI C. will be no reason for a discontinuance of the brushings, only more care must be taken not to make pressure on the cornea, and not to allow any of the nitrate to touch it. If there is an ulcer forming, the lower lid can still be brushed, and a compress bandage applied firmly over the eye, to be removed several times a day to cleanse the eye. This will probably be all that most of you will be able to do ; of course by such treatment you will only have met one part of the indications, for there is needed not only support to the weakened tissue to help it to bear the intra-ocular tension, but also a reduction of this intra-ocular tension, which is to Some extent ac- complished by the atropia. - So if it is possible a paracentesis of the anterior cham- ber should be made. If the ulcer is small, a perforation may take place beneath the bandage and no harm result further than a small opacity. - If the ulcer has perforated, and there is a prolapse of the iris, it is best to puncture it, then snip it off with the scissors. - What shall be our course in the case before us as re- gards the therapeutic management 2 I am specially glad of an opportunity to illustrate the differential treatment, if you will allow me the expression, between such a case and one of idiopathic purulent conjunctivitis. If my diagnosis is correct, we have a state of things that will rid the patient of these granulations provided we treat him properly. What is indicated ? What are we to do? I take it we are simply to be on guard to pre- vent mischief. We will prescribe a solution of atropine (gr. v.jjad.3.j), and simply have the eye kept clean. - If we cut short the suppurative stage we will interfere with the production of the very result hoped for, viz., the absorption of the granulations. Then in such cases keep in view what is to be accom- plished and only interfere when danger threatens, for example, implication of the cornea. Gonorrheal Ophthalmia. Here is an illustrative case. Not very violent, for, fortunately, the patient's eyes have withstood the worst of the siege. We still have quite an abundant discharge of pus, but the lids are not nearly so swollen as they were two days ago. - - This disease is undoubtedly one of the gravest that attacks the eye. . It is, if you please, an exaggerated purulent conjunctivitis. The cause is very virulent, and hence we have a correspondingly active inflamma- tion. The early symptoms differ little from those usually given for other inflammations of the conjunctiva, but pass on far more rapidly to the characters that corres- pond to so grave a disease, viz., extreme swelling of the lids, they are hot, red, and Oedematous; the conjunctiva is swollen and greatly chemosed, so that the cornea is almost hidden by its rolls. The purulent discharge is thick and yellow, profuse, running out upon the cheeks as it does in this patient's right eye when the lids are opened. You see that we are really in the presence of symp- toms of a violent purulent conjunctivitis. The history of the case makes us call it gonorrheal ophthalmia. An inflammation produced by getting some of the urethral pus into the eye. - Gonorrheal ophthalmia is a purulent conjunctivitis produced by contagion in the manner just stated. Even the discharge from the urethra termed gleet, the remains of gonorrhea, may produce a violent purulent conjunctivitis. So patients should always be on their guard so long as any discharge remains. We have seen then that here we have to do with an exaggerated purulent conjunctivitis, differing in degree, but not in kind. What are the therapeutic indications? If symptoms of conjunctival irritation appear in a patient suffering from gonorrhea they must be immedi- ately combatted by morphia or atrophia solutions, if considerable swelling is already present, I would recom- mend the same kind of treatment that I have given for commencing ophthalmia neonatorum, a weak solution of nitrate of silver used several times a day; even brushing the lids with a moderately strong solution and afterwards using ice or ice-cold compresses. The further indications differ in no respect from those in purulent conjunctivitis. sº e-ºn- -** wº A Vindication of the Hydrate of Chloral. BY C. W. CRAM, M. D. Columbus, Ohio. I read with much interest, in the January number of the London Lancet, the views of one of our own eminent surgeons, Dr. N. R. Smith, of Baltimore, regarding the use of the hydrate of chloral, but I cannot adopt his views. The article in question is headed “The Toxical Effects of Chloral Hydrate when persistently used as a Hypnotic, and Fatal Results of Large Doses.” To sus- tain the views here indicated the Doctor presents several cases that came under his care, observation or knowledge. Two cases in which toxical effects resulting from its continued use were claimed, were very similar. There was an eruption upon the fingers, erythematous inflam- mation, desquamation, with ulceration about the nails in each case. Upon inquiry it was found that, in each case, chloral had for sometime been taken for its hypnotic effect: and the eruption was concluded to be a conse- quence of its poisonous influence upon the blood. But not only at this point does chloral appear under the ban, but its evil influence, according to the belief of the parties concerned, still continued in the two cases; for while the eruption was apparently cured by topical MAR 2, 1872.] TIE-ITEB C T , T IN IT. C. 99 applications; in case No. 1, the patient, a gentleman of seventy years of age, was, after a few weeks, attacked with bronchitis, of which he died; while in case No. 2, the patient, a young lady of twenty-two years, was attacked with albuminuria, accompanied with general anasarca of which she finally recovered. And for these subsequent attacks—one of them fatal, chloral was held to answer as the cause. - Now is there anything in this outline sketch of these two cases that will warrant such a conclusion ? On the contrary, are we not justified in the belief that chloral had nothing to do with the abnormal condition as rep- resented in the eruption, save as a co-incident, and that it was innocent of any connection with the subsequent illness in either case? - Of course some systemic ailment preceded the erup- tion, causing pain or inability to sleep or the chloral would not have been called for ; and it appears to me by far more reasonable to associate the double illness in each case with this anterior ailment, as a pre-existing cause, rather than with chloral. H remember very well a case that was, in my belief, exactly in point with the two above given. It occurred over four years ago in the hospital to which I shall soon allude more in detail in connection with this medicine. It was a case of desquamative eruption upon the mid- dle third of the right leg, extending from the tibia out over the fibula, and occupying a space equal to the palmar surface of the hand. I had not then and have not since seen anything like it; and I have tried with- out success to class it in the books on skin diseases; but whatever it was, it certainly did not have chloral for its cause, as it was before this medicine was known. The patient was a strong man, apparently, but of sickly look, of about forty-five years of age. He stated that attempts had been made to cure it, but without avail. As he made no complaint aside from the local trouble, I applied remedies only to the part involved; and brushing this with creasote diluted with five parts of glycerine, and following this with lint saturated with olive oil, I had the pleasure of Seeing the parts com- pletely well in less than two weeks. But this pleasure was of short life. In a few days the man returned to the hospital looking deathly sick. There was entire loss of appetite, and anemia and emaciation rapidly ensued. Aside from these manifestations, his disease was obscure. He was in the hospital about four weeks and was considered dangerously sick, but he recovered under the active use of tonics and stimulants, and forced nourishment. Now my belief was then and is now, that this attack of sickness was due to systemic ailment that existed prior to and was the cause of the eruption; and that the suppression of the eruption without recog- nising and acting upon this fact by administering inter- mal remedies, had more or less to do with instituting the subsequent sickness, and was, consequently, bad prac- tºge, Dr. Smith follows the same plan of medication with the same result, and then attempts to throw the responsibility of the final result upon chloral. Next to these two cases comes one in which a young man, after taking a very large dose of chloral, was found dead upon the floor of his room, and his death attributed to this medicine. Now as there was no post-mortem ex- amination in the case, it cannot be known that his death was not due to some internal lesion with which medicine had nothing to do. But if we attribute death to chloral, it may have been only a remote cause, while a fall upon the floor was the immediate cause of the fatal result. The effect of this medicine is as stealthy as it is rapid; the patient under its influence often fall- ing asleep before he is aware of any such pending dispo- sition. Consequently we can easily see that a person, after taking a very large dose of it, might attempt to walk across a room, and, suddenly seized by its influence, fall to the floor and die; the death being largely due to the fall; while, over the same person quietly in bed the same amount of the medicine, although a very danger- ous dose might not prove fatal. Then follows a case in which death was attributed to this medicine, which was supposed to have been given in an ordinary dose, although it was preceded by a hypo- dermic injection of morphine, the amount of which was not known. Now it is singularly strange to me that one of so large an experience as the writer of the article in question, should hold the fatal result in this case to be “manifestly from an overdose of chloral.” Has the hypodermic injection of morphine, since this method of its use was first began, been wholly innocent? Possibly it has been in the hands of Dr. Smith; but there are practitioners of high standing who consider it dangerous to a degree that wholly forbids their use of this instru- ment, save in exceptional cases, where the morphine is contra-indicated by other modes of administration; and in these cases they govern its use with the most scru- pulous care. With this fact in view when there is a hypodermic injection of morphine in unknown quantity by an irregular practitioner, and this followed after an unknown length of time by a dose of chloral, and this followed by death after a space of time equally unknown —all of which occurred in the case under consideration, we should be very slow indeed to arraign chloral on the fatal result, while we allow morphine and the hypoder- mic syringe to go free. The next and last case presented is one where the death of the patient was supposed to be induced by the injection of a drachm and a half of chloral. In order to understand with any degree of certainty the connec- tion existing between the medicine and the fatal result in this case, it is important that we should have some knowledge of certain points upon which the article in question gives no information. The patient had sub- mitted to a severe surgical operation. Yet we are not told whether anaesthetics were used or not, or whether the shock to the system was light or severe, nor are we informed as to the length of time that elapsed between the operation and the administration of the chloral; in fact we are left wholly uninformed as to the nature of 100 T IEEE IET: C T I I INT I C - [MAR. 2, 1872. the operation and the condition of the patient following it. But passing by these essential conditions to the fair understanding of the case, without which no one can form a reliable opinion as to the cause of death, I think it safe to assert that the amount injected was three times too large. Not over half a drachm should be injected unless the patient is accustomed to its use. Now if a physician administers three times the proper amount of this medicine, and death results as a conse- quence, is the medicine responsible? If a physician in treating paralysis gives a large and fatal dose of Strychnia, is this remedy to answer for the result 2 . The aw of itself is a harmeless implement of industrial use and of much value, but if anyone using it as a wea- pon, destroys life with it, is the aa, to be held account- able? Or does the guilt rest upon him who, as the active controlling agent, either thoughtlessly or pur- posely belies the true character of the implement by instituting for it an improper and illegal use? The answer is evident. And yet we often exonerate the active, culpable agent, while we censure that which is only passive. Now, having in our experience, formed views differ- ent from those advanced in the Lancet article, we will proceed to give them and the leading facts upon which they are based, In the Hospital of the Ohio Penitentiary, there are at present 43 patients, which is about the average number, exclusive of out-patients. Of this hospital I have im- mediate charge through the night; Dr. N. Gray, a prac- titioner of large experience having general charge, but visiting the hospital during the day. Now by reference to the books I find that 43 lbs. of the hydrate of chloral have been given our pstients during the last twenty-two months. This amount at 20 grs. a dose, would give 1,662 doses, certainly a sufficient number to form reli- able data. Being in the hospital and among the patients during the whole night, I have a good opportunity to see the effects produced by this class of medicines. Watching these effects, I have been very strongly impressed with the great value of chloral. Here are what we deem its advantages:— 1st. It is prompt in its action, sleep being almost invariably induced in from fifteen to twenty minutes unless the patient has become accustomed to its use. 2d. The sleep it produces is remarkably quiet, being very seldom disturbed by dreams or any other form of restlessness. • 3d. Its action is not complicated by those disagreeable attendants that so often follow the use of the prepara- tions of opium, viz., nausea, constipation and paralysis of the bladder; the former, in some cases, in anticipation, strongly contra-indicating the use of any form of this drug. #. Its use is not followed by that craving for its continuance which so often attends the administration of the preparations of opium, particularly morphine, producing a multitude of opium eaters. 5th. It is safe, when given in a proper dose. We will now notice these five points in their order. a. That it is promptin its action is undisputed. And this is of much importance, as there are many cases that require to be brought as quickly as possible under the influence of some medicine of this class. It is more prompt, and in our belief more safe in its action, than . morphine by hypodermic injection. b. Not only is sleep undisturbed, but respiration is remarkably easy and regular. I have not seen a single exception to this. There is one among our number of patients who cannot take morphine without producing while asleep, a condition in which he will “catch” his breath, the respiratory acts taking place only from three to six times a minute. I have several times waked him from this, as I supposed, dangerous condition. Yet he was not in the least narcotized. On this man chloral has no such effect; but, sleeping under its influence, his respiration is easy and natural. This is a patient with tuberculosis. Another patient, with the same dis- ease, had occasionally been taking 3 gr. doses of morph- ine to quiet pain. One night he was unable to obtain sleep, and I gave him a full dose of morphine twice with- out any effect. Dr. Gray, when he made his call in the morning, ordered the same by hypodermic injection of 3 gr., but it had no effect. In the evening I repeated it with no better result. After three hours had elapsed, as he objected to the syringe, I again gave it by the mouth. This was continued until he had taken, during the night, 2% grs. of morphine, with no other effect, ap- parently, than to make him more wide-awake than be- fore. He expressed himself as feeling “mighty good,” but was the farthest from sleep possible. This condition continued through the day. In the evening I gave him thirty grs. of chloral, and in twenty minutes he was in a quiet sleep, in which he continued for three hours. When he awoke the same amount was repeated, when his sleep was continued through the remaining portion of the night. - This is but one of several similar cases that have occurred in the hospital; and they prove that under certain circumstances, the hydrate of chloral has a power that morphine, though given in what might be at another time a fatal dose, does not possess. c. As to the troublesome attendants that often follow in the train of opium, and its preparation :-that they are not associated with chloral, is very evident indeed. We have never seen them, have never heard of them, and have never read of them save in some uncertain cases. There were two or three cases among our patients in which its use was followed by diarrhoea; but as it was at a season of the year when this disorder was pre- valent, and as chloral has been at times successfully given in the treatment of the same, it is but fair to pre- sume that the complication was due to some cause other than the medicine in question. - For some time past, in order to ascertain as far as possible the relative merits of chloral and morphine, as ‘MAR, 2, 1872.] TIEHC E C I I INTI C. 101 sleep-producing agents, I have made diligent inquiry of the patients upon this point, but have not yet found the first instance where the chloral has been followed by indigestion, nausea, vomiting, loss of appetite, constipa- tion or paralysis of the bladder; while, upon the other hand, all of these often follow the administration of morphine,—a general interference with the Secretions as well as excretions, taking place; and so often does vomiting follow it that the cautious and conscientious physician can hardly prescribe this medicine without feeling that he is about to inflict upon his patient the torments of a slow emetic. d. It is well known to all physicians, that morphine, when administered a number of times successively, has a tendency, in some cases, to excite a strong and alarm- ing desire for its continuance—this desire soon culmin- ating in a complete infatuation, in which the patient is powerless to resist its influence. And there are cases known to almost every physician where the unfortunate victims of this habit take from half a drachm to a drachm of morphine daily. This is no exaggeration. We know of three such cases, one of them in this city. And we recently learned of a respectable young lady yet in her 'teens, who, without the knowledge of her parents, takes constant care to keep in possession for daily use, this trouble-defying, but nerve killing drug. And cases where several grains are taken daily are quite numerous. A few years ago, in an adjoining county, one of the most popular ministers of the Methodist Conference, com- mitted suicide, simply from the fact that he was an opium eater; and having for years struggled, with mind bordering upon despair, to break the hold of the evil influence, he finally determined to terminate the contest by terminating his own life. Now the miserable condition of persons who are addicted to this fearful habit, is almost invariably brought about—by the prescription of a physician, who, to lull the aching nerves, or induce sleep, has dosed and dosed with some form of opium, thoughtless of conse- quences. That this condition can be avoided in many instances, by the use of chloral, we firmly believe: and this consideration alone, where other points are supposed to be equal, should instantly turn the scale in favor of chloral, in all cases where a favorable prognosis is enter- tained; for this medicine appears to have no more ten- dency to arouse desire and set up a pernicious habit in its gratification, than does quinine. - e. It is safe, comparatively. As a rule, medicines of real value, will, if improperly given, prove capable of producing very injurious results; such a medicine is chloral. an instrument of evil, if not well directed. Of the 4; lbs. of this medicine used as already indicated, not a dose has given rise to an unfavorable symptom, either in immediate or remote effect, as far as I am aware. Certainly no death has resulted from its use. One patient, a female, sick of pulmonary tuberculosis began taking it over six months ago. In her case it does not Powerful for good, it is necessarily efficient as | seem to loose its effect, for she is still taking it, and the dose has not been increased. She appears to derive much benefit from it; for though sick for over two years, and a year ago considered likely to die at any moment, she still lives. Another patient, a male, prostrated by paralysis, took this medicine for over three months. He improved slowly, and is now at work. Another has taken it for over three months, and is much better than when he began its use. Others have taken it for three or four weeks, without any appearance of, or increase of anaemia. And no eruption has ever been seen upon the body or extremities that could be attrib- uted to its influence. We have usually given this medicine in 20 gr. doses, increased to 30 grs. where the patient has become accus- tomed to its use. In case of its failure to act promptly the dose has been repeated in half an hour but not Sooner. It is of the highest importance that great care should be exercised to determine the necessity for a repetition of a dose. Its influence extends through sev- eral hours; consequently, if two or three full doses were to be pushed rapidly at intervals of only fifteen or twenty minutes, when, with the exercise of a little patience the first dose would be sufficient, it might possibly prove that the cumulative influence would be at least enough to excite anxiety to the result. Now it appears to me that this encouraging experience with this medicine, involving its use in about 1,660 doses, is sufficient to go far in warranting its general use as a hypnotic. And I cannot see that there is any thing reliable in the Lancet article that will conflict with this view; for of the five cases therein adduced in oppo- sition to chloral, only two—the “eruption” cases, were within the purview of Dr. Smith's own knowledge; and to these he was called after the chloral had been given by other parties. While for chloral I write what I do know when I claim for it, in this hospital practice, ex- ceedingly marked and beneficial effects: this knowledge of its effect being acquired by attention to the sick through the whole night, which is an opportunity for studying the action of medicines used for hypnotic effect that but few possess. The claim of the article in question, that chloral pro- duces an eruption upon the extremities on the same principle upon which ergot prodnces dry gangrene, we cannot adopt; and the theory that chloral produces its effects by the liberation of chloroform in the blood, is, in our belief, hardly to be credited; for it appears to have an action distinctly its own, which is farther re- moved from chloroform than from alcohol. —-º-º-º---— A VENERABLE SURGEON AND A TOUGH PATIENT.- A short time ago Dr. Joseph Stevens, now in his 82nd year, amputated a thigh of a patient, 66 years old, for obstimate and extensive ulceration of the foot and leg of forty years duration On the second day the patient sat up in bed, and shaved himself, and before the end of a week was able to get out of bed, without assistance, each morning, to have his bed arranged. 102 [MAR. 2, 1872. TIEI IEH C T , I. NT I. C. C o A L D Us T IN T H E L J N G s. Anthraeosis Pulmonum (Strattorn), The Ceal or the Miner’s Lºng. BY DR. LUDwig HIRT, (Breslau). A Chapter selected from the Anthor's work on “The Eiseases of Labor- ers from the Inhalation of the Manufactory Dusts” (Die Starºbinhala- tions Krankheiten, Breslau, 1871.) Continued from No. 8. In the portrayal of the history of this affection we have already taken occasion to remark that the influ- ence of coal dust upon the health of the laborer has been made the subject of manifold investigation for a long period of time. We have discussed also the fact of penetration of this dust into pulmonary tissue and the pathologico-anatomical changes there induced. We pass now to the investigation and discussion of further points; the influence of coal dust upon the individual organs of economy, upon the genesis of individual dis- eases and the sanitary condition of coal workers in gen- eral. Such investigations regarding of course the rates of disease add mortality among these laborers are only of value when deduced from extensive statistics. It is lamentable, therefore, that all the works which treat of the influence of coal dust upon laborers, thorough as they are in some points, have, with few exceptions, disregarded statistics, or at least furnished them so scantily that definite conclusions are almost impossible. True, such statistics are not easily attained. Avocations implying an uninterrupted inhalation of coal dust are but few, as among 12.647 laborers whose diseases the author has studied, but 49 were workers in coal. But we may draw into the field of statistics—and we are perfectly justified in so doing when we are treating of the frequency of individual diseases—the laborers in coal mines themselves, and thus in marked degree facilitate investigations. To this intent the author visited the Knappschaftsverein of upper Silesia where thanks to the kindness of Dr. Lörve in Siemianonitz and director Scholinus in Tarnowitz he was put in possession of the sanitary reports for the six years 1862-67 whence the following statistics are drawn.t Concerning now first the morphological condition of coal dust it is to be remarked that stome coal presents under the microscope as sharply defined, polygonal or rounded, only seldom sharp pointed molecules, while # These reports, as the author has subsequently learned, were also need by Moll in his Inaugural Dissertation “Die Krankheiten der Bergarbeiter in Allgemeinen und der Oberschlesiens in Besonderen,” Berlin, 1869. wood coal, on the contrary, consists almost entirely of sharp, pointed, almost arrow-shaped particles showing at times unmistakably the nature of wood. Chiefly, however, wood coal is recognized by the circular orifices, the porous canals of the coniferae and by the brownish color which thin layers display. The soot, finally, an extremely fine, foose impalpable powder, shows no trace of angular or pointed molecules, consists rather essentially of roundish modules in conglomerate apposi- tion. When impurities are present in the dust—what is not seldom the case—they are easily detected under the microscope. It is of significance as to the effect when particles of flint are encountered ; they are recog- nized by their sharp, angular borders. Dust may con- tain even 30 per cent. of these impurities; the evil effects induced are referable then solely to them. Let us pass now to the consideration of the influence of coal dust upon the health of laborers and the method of its action. As we have already remarked the most different, at times even diametrically opposed, views have been proposed. On the one hand the inhalation of coal dust is considered as not wholly free from danger. Supporters of this view are Parent-Duchatelet, Pantries, Patissier, Vernois, Guillol; it may be, they claim, perfectly compatible with health; Beddoes even goes so far as to prescribe it medicinally. On the other hand there are those who regard it as one of the greatest enemies to health, an enemy which destroys all lungs and all Iaborers compelled to breathe it, which induces an early consumption and death. Supporters of this view, or in modifiéd form, are Mélier, Tardieu, Kuborn, Seltmann, Cox. Between these two extremes, as advo- cates of peace, stand Riembault, Böens-Boisseau and others who attempt to reconcile and harmonize the opposing views. The position of the author will be Iearned from the conclusions based upon the statistics furnished. **.* In order to obtain an idea of the general effect of coal dust inhalation it is perhaps best to investigate its influence on the individual organs of greatest importance and to ascertain the frequency of their diseases; it is of course proper that the respiratory organs as those most affected and endangered should receive the closest re- gard. Of the organs of respiration the bronchia shall first engage us. ' Almost all observers fully agree in the fact that the bronchial mucous membrane in constant or frequent contact with coal dust is strongly disposed to acute and still more to chronic affections, particularly catarrhs characterized by the expectoration of black sputa. The result of our observations fully confirms this condition and it is evident from the above mentioned sanitary report that next to rheumatism—that unavoid- able plague of miners—bronchial catarrhs claim the highest per cent. of all internal diseases. During the six years 1862-67, 30.879 miners suffered with internal diseases, of these 6.555, i.e., 16.4 per cent. are registered as catarrh of the organs of respiration. Further, in the district Hörde according to Sr. Martens observa- MAR, 2, 1872.] 103 - tions 11,499 suffered with internal diseases from 1842-58 inclusive; of these 2,213, i. e., 18.3 per cent. are regis- tered as catarrh (here, it is true, stomach and intestinal catarrh were included). Again, of 255 charbonniers examined by Vernois, 23 were sick; of these 13 suffered with habitual, 3 with acute bronchitis, a percentage (from very small numbers truly) raised to 69. Finally the author found among the 49 miners admitted to the Breslau (Allerheiligen) hospital during the years 1859–69, eleven, i. e., 22.4 per cent. patients with bron- chitis. There is no doubt, then, but that bronchial catarrhs hold a high numerical position among laborers exposed to coal dust inhalations, and that these catarrhs are remarkably frequently excited in this way. If we now examine the relation of coal dust inhalation to the genesis of diseases of the lungs we shall have to regard chiefly, inflammation, emphysema and tubercu- losis since other pulmonary affections—as in no way standing in this connection—may not be brought into consideration. Concerning pneumonia, then, first, We have to remark that although this disease, as we have already statistically demonstrated, occurs more fre- quently among dust inhalers than among other laborers yet it is but remarkably seldom excited by coal dust. This is a fact established alike from the extensive statis- tics of Upper Silesia and of Hörde, though the experience of the Breslau Hospital is not in unision therewith. Of the 39,879 patients of Upper Silesia 1,836, i.e., 4.7 per cent. were attacked with pneumonia ; of the 11,499 patients of Hörde 313, i. e., 3.6 per cent. were pneumo- nic while in Breslau Seven, i. e., 14.4 per cent. were sufferers from this disease. This gives us, thus, a per- centage (excepting the uncertain Breslau rates) which equals that of laborers engaged in other than “dusty” pursuits. This relatively seldom occurrence of the dis- ease is perhaps explained by the fact that the coal part- icles which penetrate into the lungs, as they (excepting wood coal) do not possess sharp edges, fail to exercise that amount of irritation necessary to inflammation. When, further, they are present in mass they merely fill the tissue and induce by gradual accumulation the alterations already described as characteristic of anthra- cosis. This condition, as is well known, may be present at times in light degree without any marked symptoms. Why it is, however, that sharp particles of wood coal may exist in quantity for years, as often enough occurs, without inducing pneumonia is hardly clear from the explanation just given. Of course, a large number of the cases of pneumonia cited must be attributed to ex- posure to cold, an agent which plays so important a role in the etiology of this affection in general. But except- ing these it must be stated that this negative property of coal dust, i. e., that it seldom or never excites an acute or chronic inflammation, is a peculiarity, a char- acteristic, which distinguishes it clearly from all vegeta- ble, even from all organic dusts. With reference to the frequency of emphysema among workers in coal we have to remark as follows: according 394, i. e., 0.9 per cent. were sufferers. | them confirmation or probability. to the statistics of Upper Silesia of the 39,879 laborers, Of the 23 patients observed by Vernois, four, i.e., 17.3 per cent.; of the 49 of the hospitals, four, i. e., 8.1 per cent, were patients with emphysema. The first pencentage (0.9) is un- precedently low. This is scarcely reached, as we have already shown, in the statistics of laborers in any of the manufactory dusts. The rates of the two others, especially those of Vernois (17.3) belong to the highest. It is certainly not to be forgotten that the last numbers are very small, hence scarcely suitable for the deduction of conclusions. When we reflect how simple a matter it is for four individuals among 23 or 49 laborers to be sufferers with emphysema without any connection with dust inhalation; when we reflect, further, what an im- mense influence so small a number at once exercises upon a percentage of cases only 23 or 49 in whole num- ber, we must certainly accept their deductions with caution until at least more extended experience lend The rates of Upper Silesia do not furnish this confirmation; they present, rather, such a low percentage for the frequency of emphysema here that we are almost constrained to believe that coal dust, ceteris paribus, has the property of preventing the disease, a view which is, of course, at once irrational and untenable. We are justified in raising these rates by the fact, on the one hand, that the lighter grades of emphysema so often present without occasioning such difficulty as to bring the patient to a physician and, on the other, that the small percentage is drawn from the few cases actually treated. The view that coal dust is an active excitant of emphysema is one of wide belief and is even now defended, though certainly without foundation. Coal dust, of itself, never induces emphysema. As a dust it may have emphysema, like any other dust, as a sequence. This is effected by the previous induction of broncluial catarrh and by the fact of the obliteration of the alveolae gradually effected by the deposition into their interior. Pulmonary tissue in proximity to affected parts has then a compensatory action to perform and then, of course, it may become emphysematous. These two cir- cumstances, catarrh and obliteration, may suffice, then, to induce an emphysema; they are circumstances, how- ever, which pertain to every other kind of dust inhaled and which do not, therefore, by any means justify the view that coal dust is a specific or frequent excitant of the disease. According to a statement made to me by Schöfeld of Brussels, emphysema is becoming much more infrequent among coal miners since they are no longer compelled to work in a stooped posture with the body half flexed, since, in other words, the passages have been enlarged so as to enable them to pursue their avocation in an erect posture. Thus we are gradually forced to the view that when emphysema is extremely frequent among coal miners, this frequency is to be ascribed to other causes than the inhalation of coal dust. We may express ourselves then, in consideration 104 [MAR. 2, 1872. T EEE THE C T , T N T C. of all these circumstances, as follows: 1.-Coal dust ea. cites emphysema, no oftener than any other organic or in- organic dust. Proof is the percentage of Upper Silesia taken from a list of 40,000 patients (coal miners) suffer- ing in six years with internal diseases, and convincing proof it remains even after increasing this percentage for the reasons stated above. 2.- The cases which do present are not to be ascribed to any specific action of coal dust upon the alveolae but to the effects of previous bron- chial catarrh, in some cases to mechanical obliteration of portions of pulmonary tissue, to over exertion, to . cold and perhaps to the more or less injurious effects of bad posture. Most essential and interesting, finally, is the study of the relations of coal dust inhalations to the development of pulmonary consumption, a question which will regard, of course, the frequency of this disease among miners, a question which thanks to the richness of our statistics admits of thorough and satisfactory investigation. [To be Concluded.] —— — —-º-o-º----—— SCHENTIFIC NOTES. TECENT PROGRESS IN CHEMISTRY.-Mr. E. C. C. Stanford, says:—I wonder what Sir Humphrey Davy would have said to any one who talked about stellar chemistry. That great man, in ridiculing the idea of lighting London with gas, triumphantly asked the famatics who proposed such a wild scheme, whether the dome of St. Paul's was to be the gasometer? Yet we cannot imagine Regent street illuminated, or rather darkened, with dips again, and to us stellar chemistry has a real meaning. Who will venture to bound a science which reaches far away through space, and with unerring accuracy tells us the composition of distant worlds and distant suns. What can be more humiliating to our small intelligences than the reflection that a distant star will photograph its spectrum on a sensitive surface with the ray of light that left it when the oldest man in this room was a boy 7 What would the great father of British chemistry have said, had he stood in the lecture room of the Royal Institution, where his great discoveries were made, and seen the burning hy- drogen extracted by our great countryman Graham, from a meteorite, the heat and light of another world; or could he look with Lockyer on the burning flames of hydrogen, which dart up from the sun to a height of 50,000 miles, or could he read the flashing telegrams which run so rapidly round our world, that all our notions of time are completely upset, and we actually receive intelligence to-day which was sent to-morrow 2 (Excuse the apparent absurdity; it only shows how powerless language is to keep up with human progress). Had he lived with us, he would have seen a large city dependent entirely for its communication with the outer world by a marvellous kind of photography, so minute that it enables a pigeon to carry a proof sheet of the Times under its wing.—Med, and Surg. Reporter. THE PAINLESS DESTRUCTION OF ANIMAL LIFE.- From a social point of view this question has no little interest. We therefore record that at the Medical So- ciety of London, October 16, 1871, Dr. B. W. Richard- son read a paper “On the Possibility of Destroying Animals intended for Human Consumption without the Infliction of Pain.” After reviewing the various means employed in the execution of this humane project, with partial success, he recommended the following vapors:–1. Hydramyle and bichloride of methylene. 2. Carbon disulphide and methylene bichloride. 3. Chloroform, or methylene and coal-gas. In sleep all Sensibility is destroyed in fifty or one hundred seconds. Two drachms is poured on domette, in a conical in- haler; the animal does not struggle; the butcher kills in the usual way; bleeding follows. First, primary syncopal convulsion (after loss of forty ounces of blood); Second, fatal convulsive paroxysm (after the loss of ten ounces more); the heart ceases to play. During narcotism the primary convulsion is suspended, or mnch reduced in force. The second convulsion (an entirely . reflex and painless phenomenon), insensibility, is quickly produced; no odor or taste is left. An ingeni- ous apparatus was shown, to contain the narcotic vapor, and to allow coal-gas to flow through. For oxen, a number of chambers could be devised, with swinging doors, through which oxen could be drawn on trucks by means of an endless chain, the chambers to be filled with the narcotising vapor. Animals could pass through the Lethal river of vapor, and be made oblivi- ous of death, at the rate of sixty per hour —sº-o-º--— MIEDICAL NEWS. LOYALTY TO SCIENCE.-The Paris Academy of Med- icine have refused to strike off the names of their emi- nent German colleagues from the roll of members, as they have been commanded to do. STATISTICS OF THE RACE,--The earth is inhabited by about, 1,380,000,000 of inhabitants, namely: 380,000, 000 of the Caucasian race, 580,000,000 of the Mongolian, 200,000,000 of the Ethiopian, 220,000,000 of the Malay races, and 1,000,000 of the American Indian. All these respectively speak 3,064 languages, and possess 1,000 different religions. The amount of deaths per annum, is 333,333,333, or 91,954 per day, 3,730 per hour, 60 per minute, or one per second. This loss is compensated by an equal number of births. The average duration of life throughout the globe is thirty-three years. One- fourth of its population dies before the seventh year, and one-half before the seventeenth. Out of 10,000 persons only one reaches his hundredth year; only one in 500 his eightieth; and only one in 100 his sixty-fifth. Married people live longer than unmarried ones, and a MAR. 2, 1872.] T EL ED CT, IT INT I C - 10 tall man is likely to live longer than a short one. Until the fiftieth year, women have a better chance of life than men; but beyond that period the chances are equal. Sixty-five persons out of 1,000 marry. The months of June and December are those in which mar- riages are most frequent. Children born in spring are generally stronger than those born in other seasons. Births and deaths chiefly occur at night. The number of men able to bear arms is but one eighth of the pop- ulation.—N. Y. Observer Year-Book. . —-º-º-º- correspond ENCE. A Case of Extra-Uterine Pregnancy. Reported by J. TRUSH, M. D. VIENNA, AUSTRIA, Jan. 17, '72. On the 26th. of November last was presented to the Collegium by Professor Carl Braun, a woman, about 30 years of age, pregnant with her third child, and then, according to her statement, near the end of gestation. She had been in the house for several days, but up to that moment had not been examined by Prof. Braun; he had been informed by one of his assistants that cer- tain anomalies were present in her case; he would now endeavor to ascertain the nature of the abnormal condi- tions. In the examination the following points were demonstrated: - gº - Patient feeble and much emaciated, although she had not been actually sick for some months past; her abdo- men was large and presented the contours of two une- qual growths, or tumors, the line of demarcation between them—a shallow, but distinct furrow—running across the abdomen from one anterior superior process of the ilium to the other. The larger one of these evidently contained the foetus and that a vigorous one, its motions being quite apparent at Some distance, and through palpation its approximate size and position were readily ascertainable—it could not weigh less than six-pounds, consequently was of fair size and lay in a so-called “cross position”, the head being high up in the left iliac region, the breech in the corresponding locality to the right. Examining in the same mannner the lower, smaller tumor, it was found to be a firm some- What elastic substance, susceptible of more or less distinct isolation from the foetal tumor, along the furrow above alluded to. To prove that this was not a distended bladder, a catheter was introduced, but only three or four ounces of urine passed off, without, in the: least, affecting the size of the growth; through the Vagina the finger came upon a tumor, similar in consis- tence to that noticed externally, it occupied the cul-de- Sac Óf Douglas and éntire right side of the pelvis. The Cervix uteri was found displaced towards the left, it was Soft, the os externum open, passable for one finger, but no foetal parts could be felt, either through the os uteri, or from any point of the vagina. The sound introduced into the uterus passed with facility, obliquely upwards and to the left, to the depth of four inches; for fear of rupturing “the membranes,”(?) no attempt was made, at this time, to pass it further, or in a different direction. From these data the diagnosis could not be made with absolute certainty, a more thorough exploration of the cavum uteri would be nesessary, nevertheless the case was believed to be one of normal pregnancy, with low attachment of the placenta and complicated with ovar- ian disease. An insertion of the placenta near the os internum uteri and the presence of an ovarian cyst, would, it was thought, account for the peculiar appear- ances of the abdomen and the condition of parts in the vagina. In the succeeding three or four days the “more thor- ough” exploration of the uterine cavity took place. A sound was introduced, as before, to the extent of four inches and then the point of the instrument directed towards the right, and, really, comparatively little pressure seemed to be necessary, to cause it to pass several inches further, but, no liquor amnii escaped, as had been anticipated would follow the execution of this maneuver; it was a circumstance that spoke strongly against the diagnosis of normal pregnancy with com- plications; the great probability now seemed to be, that the sound had passed into the right Fallopian tube, that the uterus was empty and the case consequently one of extra-uterine pregnancy. In order to clear up the last shadow of a doubt, the patient was placed under the influence of chloroform and a digital examin- ation of the uterine cavity-resorted to. It was empty —the examining finger could, on all sides, touch the parietes of the organ inside, therefore it could not con- tain a foetal head, and the larger and living foetus had attained its growth and development external to the uterine cavity. In relation to the pelvic tumor, it was still believed that its greatest bulk was due to an ovarian cyst, the remainder to the enlarged uterus and the extra-uterine placenta. Prior to the last series of explorations the patient had suffered no pain, certainly had perceived nothing like labor pains; shortly after these examinations however, abdominal pain and tenderness set in, gradually grow- ing more severe, but never assuming a paroxysmal character, accompanied by moderate febrile movement and increased frequency of pulse. Having been already feeble on entering the Hospital, the woman after the ac- cession of pain, etc., began to fail rapidly and it soon became evident that the exitus lethalis was near at hand. Nothing was to be hoped, under the circumstances, from the Cesarian section, except that the life of the child might perhaps be preserved thereby, hence her peculiar and deplorable condition and the operation re- quisite for delivery were explained to the patient, but she would listen to no such operative proceedings; she had been confined twice already in the natural way, that now it should be necessary to remove the child 106 [MAR. 2, 1872. TIEI IEH C T , IIIN IT. C. through an artificial opening, made with the knife in the abdominal walls, she could not and would not be- lieve. Nothing remained to be done therefore but to await the coming of events and act as circumstances might demand. The patient sank rapidly became un- conscious on the 3rd. and died comatose on the night of the 4th. of December. Immediately, Cesarian section was performed and the foetus removed but too late, for, though it gasped two or three times, yet the most persevering efforts at resusitation failed to establish normal respiration. . A considerable quantity of a greenish fluid was also removed at this time from the abdominal cavity of the deceased mother, but no exam- ination of the parts undertaken, it being the prerogative of the pathologist to do this The child proved to be much larger than had been anticipated; it weighed ten pounds, avoirdupois. Sectio Cadaveris, 34 hours after death. Much emaciated ; rigor mortis feeble expressed; brain anaemic; otherwise healthy; lungs, aside from hypostatic congestion normal. On opening the abdom- inal cavity the following condition of parts presented itself: At a point, about midway between ensiform car- tilage and umbilicus, an abnormal partition was stretch- ed across the cavity, formed by the transverse colon and great omentum, the latter appendage being firmly adherent to the abdominal walls, anteriorly and latterly. Above this partition lay the liver, duodenum, stomach and spleen; below it, the small intestines, ascending and descending colon, etc. The small intestines were spread out evenly over the posterior and lateral walls of the lower cavity; the several coils bound to each other and to the deeper lying partly by strong fibrous bands, giving to the whole a kind of basket-like appearance. The inferior boundary or floor of this cavity, was formed to the right, by some kind of tumor filling the iliac fossa on that side and extending some two inches beyond the median line of the body; on the left by the uterus, occupying the iliac fossa on this side and overlapping the tumor near the middle line, to the extent of one and a half, or two inches, being in front of it; and finally, by the bladder, located in front of both and in its normal central position. In the cavity thus described the foetus had been found, the greater portion of the umbilical cord still lay here, also a few ounces of turbid greenish liquid. It will be remembered that a consider- able quantity of such fluid—between two and three pints—had been removed at the time the sectio, Cesaris was made. In addition to the evidences of bygone in- flammatory processes, the adhesions, strong fibrous bands, etc., were also present those of recent peritoneal inflammation, in the shape of a pulpy exudation, dis- tributed in layers and strings over the various organs. Upon following the cord to its attachment, it was found to enter the oft mentioned tumor by an opening about two inches in diameter, situated just behind and a lit- tle above the right border of the uterus, thence to pass downwards within the envelope of the tumor to the reflection of the peritoneum and there to be inserted into its placenta. Through this opening protruded also, in a ruffle-like manner, a cream colored, shining mem- brane. More minute examination of this tumor proved it to be really nothing than an enormous placenta, enclosed in a strong membranous sack: the great size of the placenta being due to interstitial extravasation of blood which had become partially organized. The pro- truding membranes were connected with the placenta in the same manner as in normal pregnancy; they lay shriveled up on the anterior surface of the placenta and were to the greater extent, adherent to the enveloping fibrous sack. In bulk this tumor—placenta and mem- brane—was well nigh equal to an adult head. The uterus on the other hand was scarcely more than half the size usually found immediately after delivery in normal pregnancy. The measurement taken of the uterine cavity and cervix during life proved to be correct and on directing the point of the sound towards the region of the right Fallopian tube it also entered readily some kind of canal, but evidently not the Fallopian tube for, after passing through the wall of the uterus it appeared upon the free surface of the placenta sack. Laying open the uterine cavity, its interior sur- face was found lined with thick shaggy membrane— decidua vera—and the pathologist also demonstrated the orifice of the right Fallopian tube and immediately be- hind this the orifice through which the sound had passed. A fine probe could only be made to enter the Fallopian tube to the depth of two inches, there, to all appearances, it became impervious, could however be followed up to its termination near the right border of the placenta- tumor, it being located quite superficially upon the anterior surface of the same. Nothing was found of the right ovary. The left ovary and Fallopian tube pre- sented nothing abnormal. Concluding Remarks. The autopsy of the case dem- onstrated that the diagnosis made during life was as nearly correct as it was well possible to make it. True, the real character of the pelvic tumor had not been made out, nor had it been recognized that the foetus had already been born once, namely, into the abdominal cavity, and was then only waiting to be born again. But, as such cases are somewhat rare, no similar one having come under obrervation at the Vienna Lying-in Hospital during the last twenty years, it is not to be wondered that these conditions were not appreciated, even by gentlemen of such vast experience, as those who examined and diagnosed the case, Professors Braun and Spaeth. Whether or not it should be a matter of surprise that a Simpsons sound was pushed through the uterine par- ietes, when it was supposed to have entered the Fallo- pian tube and passed through this.into the foetal sack, is left for the reader to decide. * Since the autopsy it hs been ascertained that during the month of July last, this woman was treated at the “Rudolf’s” Hospital of this city for a disease presenting MAR. 2, 1872.] T TH THE CIT I I INT I C . 107 many of the well known symptoms of peritonitis. It is almost certain that at that time rupture of the primary foetal envelops occurred and that thenceforward the foetus lived and attained its full development among the intestines in the common cavity of the abdomen. As will have been perceived the location and condition of the Fallopian tube indicate that the fecundated ovum became attached to some part of the fimbriated extrem- ity of the tube and there reached a certain degree of development, when rupture of the sack and escape of the foetus into the abdominal cavity took place, followed by a mild peritonitis, this passing away without in the least, interrupting the growth of the foetus. C. LINICAL MEMORANIDA. SICK HEAD-ACHE,--The only remedies which are of: any avail are those which act on the nervous system, such as hot tea and coffee; or, after the stomaeh is quieter, and the more urgent symptoms have passed off, a little wine or ammonia. If the head-ache take more the form of hemicrania, then remedies are occasionally useful, as the local application of the bisulphide of car- bon, or galvanism, and internally the bromide of potas- sium. This is the only drug which I have really seen to be serviceable. Whilst the nausea exists and the worst symptoms prevail, even this remedy is of no avail. —Wilks—Brit. Med. Journ. QUESTIONS OF THE EXAMINATION. The Following Questions, Tem in Each Department were submitted to the Graduating Class of ’72. ANATOMY. 1. Give a general description of the skeleton. . Describe the os femoris. . What are the essential components of any entirely moveable joint? - . Describe the elbow joint. . Describe the heart. . Give its position. . Describe the larynx. . Describe the trachea, bronchi and bronchia. . What are the enveloping membranes of the cerebro- spinal axis? .” What are the great divisions of the encephalic mass and their relation ? . : . 10, SURGICAL ANATOMY. 1. What is the best place for ligating the common carotid artery, and what are its relations at that || part? - - 2. Popliteal artery, where found and relations? 8. What are the anatomical objections to ligating the first and second portions of the subclavian artery? 4 5 : : 10. Scarpa's triangle, boundaries and important parts contained. - By what muscles is the inner border of the foot elevated ? . Fractures in the upper third of radius, in what posi- tion best treated, and why? . What are the parts divided in the lateral operation of lithotomy? . Surgical anatomy of the shoulder joint. . Surgical anatomy of the elbow joint. . Surgical anatomy of the hip joint. PHYSIOLOGY. . The digestive juice with the widest range of action, and its chief ingredients? P . Trace fat through the system. . The cause or causes of circulation in the veins ? . Capillary circulation, continuous or intermittent, in either case why 7 . Chief use of the red blood corpuscles? . Uses of sweat 7 --- . The immediate and subsequent effects of wounding the cerebellum ? . The diurnal range of temperature and the variations compatible with health 7 . The necessary quantity of air in cubic feet for 24 hours? Describe a spermatozoid. CHEMISTRY. 1. Enumerate the general properties of acids and bases. i2 8 10. 5 . Give the composition, formula, and mode of prepa- ration of hydrochloric acid. . Describe the tests for arsenic. . What is the antidote to arsenic and how prepared ? . Describe normal urine. * . How is urea obtained from urine? . How are chlorine, Sulphuric acid, potassium and sodium detected in urine 7 . Describe the tests for sugar in urine. . How would you determine whether a deposit con- sists of urates, phosphates, oxalate of lime or uric acid 7 How would you discover blood in urine? SURGERY. . What are the various processes by which fractured bones unite 7 . What are the means you would use for strangulated hernia before resorting to an operation, and, fail- ing in these, what are the operations recommended and the advantages of each 7 . In what injuries of the ankle joint is deformity inevitable? . What are the stages of hip-joint disease and the treatment of each stage 7 . How would you treat wounds of the stomach 3 , What are the indications for amputation ? • - *** - , º, . 108 IMAR 2, 1 87 TIH. H. C.L.INI c. 7 10. : 9 10. : 5 6 . Describe the various methods of acupuncture. . Differentiate between intra and extra-capsular frac- ture of the neck of the femur. . Differentiate between abscess, encephaloid, aneur- ism, hernia and adenoma. - Name the principal disease which affect bones. PRACTICE. . State the prominent facts in the clinical history of malarial fevers. . What is the cause, course and termination of hepatic abscess? . What are the symptoms and dangers of desquama- tive nephritis? . Diagnosis between real and feigned epilepsy 7 . How treat habitual constipation? . What are the physical signs of pericarditis? . Diagnosis between peritonitis and enteritis. ... . . . How distinguish fixed neuralgia from inflammatory pain? . Give the dry and moistråles; what do they indicate? . How would you treat cardiac hypertrophy. GYNAECOLOGY. . Describe the uterus, location, size, weight, divisions, StructureS. . In what particulars does the neck of the womb differ from the body of the womb 7 . Describe ovulation and menstruation. . What circumstances would enable you (if possible)| to determine the difference between specific and non-specific vaginitis? . Mention the most common diseases of the uterus in the order of their frequency. . Name the various substances which may be expelled from the female pelvic organs. . Give the probable and positive evidences of the ex- istence of uterine cancer. . Mention the forms of dysmenorrhoea and differential diagnosis. . What are the conditions capable of producing amen- orrhoea? What are the diseases which may produce pelvic abscess? OBSTETRICS. . Give positive signs and duration of pregnancy. . Give diameters of pelvis at brim and outlet. . Give diameters of foetal head. . Describe the anterior and posterior lateral inclined planes, and their relations to the mechanism of labor. . Give the four cranial presentations, with the diag- nosis of the first. . Management of natural labor. p . Under what circumstances would you turn, and how 7 . Cause, symptoms, and treatment of unavoidable hemorrhage. 9. Cause and treatment of post-partum hemorrhage 2 10. Symptoms and treatment of puerperal convulsions? OPHTHALMOLOGY. 1. Name the bones that form the orbit. . Name the muscles found in the orbits giving the nerves that innervate them. : 3. Given a case of internal squint, how could you tell whether it was paralytic or not.? . Give the condition of the lids in ptosis and facial paralysis, with the muscles and nerves involved. . Give the structures of the eye from before back- wards. 6. Give the points of differential diagnosis in the various conjunctival inflammations. . Differential diagnosis of iridal and corneal inflam- mation with the general plan of treatment in the latter and the particular of the former. 8. Of what does the lachrymal apparatus consist and what may interfere with the carrying off of the tears ? - - 9. What is cataract, and what is its treatment? . What are the two methods of examining the eye with artificial light? MATERIA MEDICA. 1. Why is cod liver oil the best form in which to ad- minister a fat 2 . Describe the effects of arsenic on the primary assim- ilation. - - - 3. Name the preparations of arsenic and the dose of each. . Give the composition of opium. . What is the treatment of opium narcosis? 6. What practical tests for the purity of chloroform may be made at the bedside? 7. In danger from chloroform narcosis what methods of resuscitation are proper? 8. What is the distinction between galvanism and Faradism 2 - 9. To what class of cases are these two forms of elec- tricity especially applicable? 10. Write a prescription for a purgative pill. —º-O-ºsm-- IHION II E NEWS. THE report of the Commencement Exercises came to hand too late for insertion in this number. DR. THos. L. BROWN is about to establish himself permanently as an electrician. Brown is a master work- I (18.Il. DR. WADE MINOR LOGAN as we are informed begins soon a series of articles in a Journal of Mechanics on the diseases of laborers. Dr. Logan will work this subject up to general profit. He is blessed with the working capacity. DIVIDED MEDICINES, PREPARED BY The Divided Medicine Comy, CINCINNATI, OHIO. * The Company have the honor of bringing to the notice of the Profession, this NEW AND ExCEEDINGLY PRACTICAL METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. The Divided Medicines are prepared by FREDERICK KRAUS, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MORE. º The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every square will consequently contain accurately measured quantities. But not only SoLUBLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINES. - This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, ; : #. sh, 1.0, and even idoo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. - Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE TO SPOIL BY ANY LENGTH OF TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calls with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. For Samples, Price Lists, and Agencies, address - sº |s – S R İş. The Divided Medicine - - IECIX: 2688, Or FRFDERICK KRAUS, Chemist and Druggist, Walnut Hills, Cincinnati, O. MR. FREDERICK KRAUs: CINCINNATI, February 15, 1871. Dear Sir–The specimens of your “ Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity Specified in each, viz: - SULPH:MORPHII.......................% grain in each square. ARSEN:ACID......................... .1-20 grain in each square. “ CHIN INI ....................... 1 * * * * $6 CALOMEL 34 “ -- 66 & 6 COPPER ................. .......}% & ſº RespecTFULLY YoUBs, E. S. WAYNE, Analytic Chemist. ||||||}|| MM|| ||M|| FOSTER’s 167 E4ST 34 T LI-ST., NE IV YO It K, By Special Appointment Electrical Instrument Makers tº the New York State Hospital for Nervous Diseases, MAN UF ACTU. RERS () F PORTABLE ELECTRO-MAGNETIC MACHINES, Portable Galwanic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, 1870, and May 30th, 1871. These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery ſºluid. - |M|| |||||—|| |||||||} PEERMIAN ENT B ATTERIEs, For Hospitals and General Practitioners, TEIT IIECTIER, OTDIES. For Eye, Ear, Larynx, Nose, Uterus, Vagina, Bladder, Rec- tum, Feet, Phrenic and Sympathetic Nerves, Elec. trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. —-->O-O-c- AEXTRA ('TS JEMI NENT IM EMI E3 ERS OF THIS PIR OFESS / O N. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “Nothing cAN EXCEED THE EFFICIENCY AND CONVENIENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” We are authorized by Prof. Hammond to announce en- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- proved and re-modified Instruments made by our Company. W M EREDITH CLYM ER, M. D., Prof. of Diseases of the Neº- vous System and of the Mind, &c., &c.—“I consider their Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prof. of Surgery, St. Louis:–“ In neat- ness, compactness and efficacy, they can not be excelled.” A LFRED C. G AR 8 ATT, M. D., Boston :-" In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” Simi ar Testimonials have been received from JOHN J. CRANE, M. D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A. MURRAY, M. D.; CHAS. E. BLUMENTHAL, M. D.; E. C. SEGUIN, M. D.; ALLEN MAYNARD, M. D., Cleveland, O.; Dr. C. WANN IE, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES KELLY, Florence, O.; Dr. JOHN BECKER, Brighton, Iowa; Dr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAY ER, Wilkes- barre, Pa.; JOHN J. CALDWELL, M. D., Brooklyn, and many other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an Electrical Instrument for medical purposes. CALL OR SEND FOR CIRCULAR AND PRICE LIST. FROMr TH E O PINIONS OF THI E' WOST IF_A_TIEI, NTT Are furnished to Officers and Soldiers on Government àCCOunt. I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–why is, it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those . wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to J AMIES AL. FOSTETER. 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cincinnati, Ohio, or 172 Jef- ferson Avenue, Detroit, Mich. SAML. P. THOMAS TA II, OR, D E A LEF IN English, French and Scotch GO. O. D's, 34 West Fourth Street, CA.Y.cz.w.war zºr. Made to order of N. Y. M. Muslin and 2300 HEAVY Linen, per dozen - - - $26 00 Wamsutta Muslin and 2100 HEAVY Lin- en, per dozen - - - - - - - - 33.00 Wamsutta Muslin and 1900 Linen, per doz. 30.00 Lonsdale Muslin and 1700 Linen, per doz. 27.0) First three qualities have ALL LIN EN Cuffs and Neckbands. At above prices Cuffs are attached. Same quality of our own manufac- ture, ready-made, $3 per dozen less. Perfect satisfaction given or money cheerfully refunded. . Also import and Manufacture Men's Furnish- ing Goods. Pike's Opera-House, Fourth Street, Cincinnati; 931 Wabash Avenue, and 88 West Washington - street, Chicago. CAMARGO MANUFACTURING COMPANY. Manufacturers AND IMPORTERs of AND Window Shades, 67 Wasz Kovzzy Szarmºz, CINCINNXT, 0. H. E. BRENEMAN, Proprietor, meeting with unparalleled success. $S)\jS wº § § 9 M A F P T VVA. IN'S IN EVV B O O IX IS NOVV READY FOR CA N VASSEFS. It contains over 600 pages of read ng matter, with 250 engravings, designed expressly for this work, by the best artists in the country. Agents now at work upon it are Agents at Circleville, O., reports 25 orders in 2 days; one at Louisville, Ky., reports 175 orders in 8 days; one at Middletown, Conn., reports 200 orders in 12 days; one at Cincinnati, O., re- ports 250 in 12 days. Early applicants secure choice of territory. For circulars, terms, &c., address NETTLETON & CO., 161 Elm Street, Cincinnati, O. BASCOM & CARPENTER, Stationers, Printers —AND- Blank Book Manufacturers, 136 VINE sº DEREET, &\\\\\\\\\\p IE. D. ALBIRO & BRO. IMPORTERS AND MANUFACTURERS OF FOREIGN and DOMESTIC WOODS In Veneers, Boards and Plank, fººlinaiºhirº The only house in the Western country that saws Spanish and Mexi- can Cedar for Cigar-Box Makers We import ºn wood direct, and can sell at prices to compete with any and everybody. Also º keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. Office and Warerooms, 136 and 138 West Second Street, Veneer Mill, 507, 509, 511, 513 & 515 W. Sixth St., CINCINNATI, : - - §º: º * * Eº: - tº-ºº: º jº ---wº-ººrºº # |EEE: #=######; #|jī;=#########s º ~~~~ - Sºº lºſiºiſºtº |||}|{j =::::::::=\;\}} * - ====ºft ####: | # º # ºftºft - #=#| ||##| || ſºft ºº: -: : ########| |} #: T & ºft|####||{{=}|{{#: § ######| || º- w º Mºsº. ºº:: S$º ### {{}}|º # |# | |#######!--ºft#ºs āşşº; # - #|ſſ *ś% º §§ t; ſ † | º }; j jº - * * º §§§ # I § º # º º º "| | ##### ºftº 3. 35% wº º * £= º- # | #|| liftºft. i #|ºš ºffº #######| #|## #|| # § 2." É lºš #2% # §§ º º yº-ºº: º::::::::::= º #3:SºśS Bºžº: pº º º º :=#= § § -º- s: §§ #. - #####ººl. § Pººr. tº † : * * . . . ſ º -- w w Es - . Rºº.º.º. º % § § ź ######### º_º - "ºº" Sæs ºf dº º º jº >> % à - :--> #### bººk." Sºº-ºº: §: § 2.35% § % * sº º £º : ºr, S$ ;ºss ºftº 22::::::::: - º wº - º * * * * sº º: ; : .3 2 tº tº ſº, º - º sº - º iº g: : * w º Yºº-ºº. Sº § º, - # º:::::::sºlº: 2 § > =############ -ºº-º-º-º:Sºs jºšº -- £º:53:5. - §ºftº •: **º- **. §§§ §§§ ºf 2. £is * Ésº E. §º === sº =ºšš===Sººº %2%º %2: - š===sº 2.% ge:=- GooD sAMARITAN HOSPITAL. The GooD SAMARITAN HOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner of sixth and Lock streets. It is handsomely furnished throughout, and is provided with all the necessary ap- pointments of a First-class Hospital. Porticoes, with commanding views, surround the whole house, and wide halls and abundant windows secure that full and free ventilation which is so essential to health and comfort. Service is furnished by the sistºrs or on ARITY, Under the Superintendence of the well-known SISTER ANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. The regular Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each Professor presiding over his own especial department. Patients may, however, select from the regular profession of the city any physician of their choice. The GOOD SAMARITAN HOSPITAL presents extra inducements to Invalids throughout the State as a safe and quiet asylum in any case of protracted illness, or in cases, more particularly, requiring Surgical Operation, where some stay is necessary in after treatment. Rooms vary in price, according to the character of appointments necessary and service required, ranging, in general terms, between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand ot Bºy" Address, SISTEF, ANTHONY, Hospital of the Good Samaritan, Corner of Siacth and Lock Sts., Cincinnati. Ohio- Manufacturer, Nº. 9 and Il Bast Sixth Street, bet. Main & Sycamore. I MAKE NOTHING BUT "62 /*A*, Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of - 4. - - - LIGHT FAMILY CAFFIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive variety of light elegant designs of different cost and finish. In vehicles especially adapted to The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. - - The superiority of my light gentlemen’s buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price lists furnished on application. References 'to Dr. W. W. Dawson and all the leading gº º * * º 㺠iºsº ºf ſºlº ſº§§§ -- tº . § 9 ºff; º; ºº::=&ºi=#####: ^^%: É tº Sº: º f º i; # iº ºft Sº lºš sº ºº: sº ºft illilº; § || §§§ ºf º i: ". | E. #. ##| §: # º # º § | º #. |ftº: ; ||##xºj|#: ſºſºlſ||: | - §§ # | sº º É t º: Hirº § sº º; F: ; º § º S; º: |####|# §§ # | º #|ſºſº ||3: |#: #|#### #: º i º: |; | i. # º|º : ;º i # E- E E. Sº| º ſ #= -: E š =. CINCINN ATI. E" A C TU L T Y - J A M E S G R A H A M, M. D., D E A N, Professor of the The ory and Practice of Medicine and Clinical Medicine. ROBERTS BARTHOLOW, M.D., W. W. DAWSON, M.D., Professor of Materia Medica and Therapeutics. Professor of Principles and Practice of Surgery and Clinical Surgery W. H. GOBRECHT, M.D., C. D. PALMER, M.D., Professor of Anatomy. Professor of Medical and Surgical Diseases of Women. P. S. CONNER, M.D., - T. A. REAMY, M.D., Professor of Surgical Anatomy. Professor of Obstetrics and Diseases of Children. W. W. SEELY, M.D., JOHN L. CLEVELAND, M.D., Professor of Diseases of the Eye and Ear. Lemonstrator of Anatomy. SAMUEL NICKLES, M.D., CHARLES KEARNS, M. D., Professor of Physics and Medical Chemistry Assistant to the Chair of Surgery. .J A MC HD S T - W H ITT A 13 FC R, , Professor of Physiologv and Secretary of the Faculty. Janitor, College Building, Sixth St., bet. Vine and Race. *- T. Louis Brown, Prosector of Anatomy. Printed and Published by Nor his & M URRY, Medical College of 9hio Building, Cincinnati, INIC. PUBLISHED EVERY SATURDAY. T E R MS-$2.00 a Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editor : All Communications relating to Business, Subs criptions, Advertisements, etc., to the Treasurer. Vol. 2. C IN C IN N A TI, –sº M A R C H 9, 1872. No. 10. wº Q.º sit Editor. JAs. T. whitTAKER, M. D. No. 101 West Ninth Street, Cincinnati, Associ..A.T.E. EDITORs. W. W. D.Awson, M. D. THAD. A. REAMY, M. D. P. S. ConneR, M. D. C. D. PALMER, M. D. W. W. SEELY, M. D. SAMUEL NICKLEs, M. D. coars e co- Fashionable Hatters, IMPORTERS AND MANUFACTURERs OF CHAs. KEARNs, M. D. JNo. L. CLEVELAND, M. D. - Roberts. BARTHôLow, M. D. . . . - A Yº iſ& 9) -->gº - . — ........| Hºş’ FºS W. W, SEELY, M. D., • * * sº * = tº & º TREASURER. łºńºß Sº No. 118 West Seventh Street, Cincinnati. . . . . . . . . -- . . t - - - -- - 92 WEST ENOTTERTH ST. C L U B R A TES, _** y --~~~ ' -- ... ' Past office, - - * º ' ' || 4 Copies to one address $ 7.00 || CIN 6 § { “ --------------------------------------------.......... 10,00 ſ sº special Inducerments to Medical Men. 12 § { 6 & 18.0% - o o N T E N T S. .." — Päge *. origiNAL ARTICLEs Corpulence, by J. L. Cleveland, M. P.” * - - - - - 109 Solid Food in Typhoid Fever, by Sam’l D. Turner........................... 109 scIENTIFIC NoTEs Signs of Death........................................................................ *J. TAFT W Tart. ſº 3. e - gº TRANSI LATION Coal Dust in the Lungs, (A Chapter from Hirt's Staub-Inhalations Krankheiten, Breslau, 1871.).................................................... 102 118 Books and Pamphlets Received—Journal Changes (CILINICAL MEA. IORANIDA Treatment of Sick Head-ache—The Relative Value of the Quinine Salts... s - - - - - - - - - - - - - - - - - - - - - - - 118-119 HOME NEWS II Q The Spring Course of 1872.......................... 120 The results of investigations into the influence of coal dust upon the genesis and course of pulmonary con- sumption, showing as they do conclusively, that the inhalation of this dust is decidedly prophylactic, are as gratifying as unexpectéd. The whole article is worthy of the careful study of the sanitarian, The signs of death as exhibited by Caspar in his recent work on Med. ical Jurisprudence, as the latest on this subject from the highest medico-legal authority in the world, are of J. & W. TAFT, TIENTIST's 17 WEST FOURTH STREET, CINCIN NATI, O. The Registers A Monthly Journal, no less importance in a forensic point of view: Allbutt's views as to the nature and treatment Óf sick head-ache cannot fail to interest any physician who has had to CONTAINING 48 PAGES, deal with this malady so distressing and so intractable. Devoted to the Interests of the Dental Profession, O' D C F& L IRC S S A N ID IP A. L. A. T A E L E - In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERS & BARTLETT, of Portsmouth, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. § Our notice was ed to this Oil-by several leading physicians of the city, who had as not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachilic Affections, in Chronic Rheumatism, &c. The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. * # We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. william Autenrieth, \ No. 71 west sixTH stre+BET, BETWEEN WAINUT A&E WINE, CINCINNATI, OHIO, MANUFACTURER OF AND DEALER IN ||| || || |||||||} Abdominal Supporters, Trusses, CLUB-F00T SHOES, SPINAL APPARATUS, ETſ Keeps constantly on hand a full variety of Metalic and ERubber Syringes, Stormtach Pumps, Etc. STOCKINGS FOR WABDCOSE WEDNS, Special attention given to the fitting of Apparatus for Deformities. Lºſ Agent for DR. L. A. BABCOCK'S Silver Uterine Supporter, --ALSO– DR. AHL'S POROUS FELT SPLINTS, --ALSO – D A. Y. * S S R T, IN T S -AND- ROBERT CLARKE & G0°S. LIST QF NEW MHL iTH II MEHull; Hill; GREEN'S PATHOLOGY AND MORBID ANATO MY, 8vo. Cloth. $2 5o DUCHENNE'S LOCALIZED ELECTRIZATION. 8vo. $3 oo DILLENBERGER ON WOMEN AND CHILDREN’S DIS- EASES. 12mo. $1 75 BENNETT ON PULMONORY CONSUMPTION. 8vo. $1 50 FIRST HELP IN ACCIDENTS. 12mo. $1 50 BEASLEY'S DRUGGIST RECEIPT BOOK. 8vo. $3 5o ECHEVERRIA ON EPILEPSY. 8vo. Cloth. $5 od HOWE ON EMERGENCIES. 8vo. $3 oo HAMMOND ON NERVOUS DISEASES. 8vo. $5 od RINDFLEISCH'S PATHOLOGICAL HISTOLOGY. $6 oo WARINGS’ PRACTICAL THERAPEUTICS, 2nd Am. Ed. 8vo. Cloth. $5 oc Leather. $6 oo SCUDDER'S SPECIFIC MEDICATION. 12mo. Cloth. $2 5o TANNER'S HANDBOOK OF OBSTETRICS. 12 mo. $2 oo VAN BUREN ON DISEASES OF THE RECTUM. 12mo. Cloth. $1 5o FLINT’S EXAMINATION OF URINE. 12mo. Cloth. $ 1 oo VOGEL ON DISEASES OF CHILDREN. 8vo. Cloth. $4 50 BEARD AND ROCKWELL’S MEDICAL AND SURGICAL ECECTRICITY. 8vo. Cloth. $4 50 ATTFIELD'S MEDICAL CHEMISTRY. 12mo. Cloth. $2.75 Leather. $3 25 BARTHOLOW'S HYPODERMIC MEDICATION. 12mo. Cloth. $1 5o TURNBULL’S DISEASES OF THE EAR. 8vo. Cloth. $5 od TILT'S CHANGE OF LIFE. 8vo. Cloth. $5 od NEUMANN'S HAND-BOOK OF SKIN DISEASES. 8vo. Cloth. $4 oo ANSTIE ON NEURALGIA. 8vo. Cloth. $3 OO. PANCOAST'S OPERATIVE SURGERY. 4to., with many plates. $1 o oo HOOD ON BONE SETTING. 12mo. $1 50 RINGER'S HAND-BOOK OF THERAPEUTICS. 8vo. $4 oo HOLBROOK’S PARTURITION WITHOUT PAIN. I 6mo. $1 oo PROCTER'S LIGHT SCIENCE FOR LEISURE HOURS. 12mo. $1 75 BERNARD’S PHYSIOLOGY OF THE HEART. 5o cts. BARNES’ OBSTETRICAL OPERATIONS. 8vo. $4 50 NICHOL’S FIRESIDE SCIENCE. 12mo. $1 5o. WOHLER'S MINERAL ANALYSIS. I 2 mo. Cloth. $3 OO PLATTNER'S MANUAL OF ANALYSIS WITH THE BLOWPIPE. 8vo. Cloth. $7 50 JEFFRIES ON THE EYE. 8vo. Cloth. $1 oo MANSFIELD, A THEORY OF SALTS. 8vo. Cloth. $4 oo JEFFRIES ON THE SKIN. 8vo. Cloth. $1 oo GARDENING FOR PROFIT. 12mo. Cloth. $1 5o PRACTICAL FLORICULTURE. 12mo. Cloth. $1 5o FULLER'S SMALL FRUIT CULTURE. 12mo. Cloth. $ I 5o WOODWARD'S COUNTRY HOMES. 12mo. Cloth. $1 5o DARWIN’S ORIGIN OF SPECIES. 12 mo. Cloth. $2 oo ARTHUR'S TREATMENT AND PREVENTION OF DE- CAY OF THE TEETH. 12mo. $1 5o TYND ALL ON LIGHT AND ELECTRIC1TY. 12mo. $1 25 THE AMATEUR MICROSCOPIST. Small 4to. $1 75 BOOKS IN PREPARATION. BRYANT'S PRACTICE OF SURGERY. BARNES ON DISEASES OF WOMEN. ROBERTS ON RENAL DISEASES. GUERSANT, SURGICAL DISEASES OF WOMEN AND CHILDREN. Medical, Scientific, and other Catologues sent on application. Any book in the above list sent by mail or express, free of charge on receipt of price. S. W. Eſiliott’s Saddle-bags 65 West 4th Street, Cincinnati, Ohio. List of Pharmaceutical Preparations, MANUFACTUREID BY won.w’ Irrazºn 4 amoznan, FEIILADELPHIA. —dº ELIX, PHOS, IRON, QUININE AND STRYCHNIA, ELIXIR OF GENTIAN FERRATED, ELIXIR, WALERIANATE OF AMMONIA, (Goddard’s Formula,) ELIXIR VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, Iron, with Phosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Iron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK, ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, - COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER WINE OF IRON, Citrate of Iron and Peruvian Bark, FERRATED CORDIAL ELIXIR, ELIXIR CALISAYA BARK, WINE AND BISMUTH, ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, *}. TASTELESS COD LIVER OIL, TASTELESS COD LIVER OIL. FERRATED, - e BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and Sherry wine, ELIXIR WALERIANATE OF STRYCHNIA, -r * WINE OF PEPSIN, SYRUP SUPERPHOSPHATE OF IRON, ELIXIR OF BISMUTH, COMP. FLUIDEXT, BUCHU AND PAREIRA BRAWA. * STUTEPIEPOSITOTER, II ES. Rectum, Vaginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great eare, and of every variety of combination. Lists sent on application. SPONGE TENTS.—For the Urethra, of every size and Btyle, made of finest quality of sponge. FosſºR, JR., & co. Instrument Makers and Practical Opticians, Beg leave to return thanks for the patronage extended to them through a long series of years (having been established since 1836), and in the reorganization of their firm will endeavor to merit a continuation of the same. We wish it understood by the Profession and the Public generally that our invariable rule is, to make or import none but the best in- struments. Those in want of any of the acknowledged good aids of vision to imperfect eyes, will always find the best and largest stock of Lenses, Spectacles, and the best models procurable, with pains- taking skill to adjust them to all conditions of sight, at our house. Special attention paid to orders for Fine Microscopic Objects and Microscopic Apparatus, Magnifiers and Readers in great variety. edical Batteries, Barometers, Thermo- meters, Hygrometers, Urinometers and Rain Gauges, of the most approved constraction always on hand. All orders promptly and accurately filled. - . . . - JAS. FOSTER, JR. F. S. SHACKLEFORD, } *** * JAs. FostER, JR. & Co. S. W. Cor. Fifth & Race Sts., Cincinnati, 0. TIER,.S. INT.INMA ER.S.H.’s -tº :Sºx) TRUSSES. gº - - No. 758 BROADw AY, NEw Yoes HAVE been in the habit. of applying and recommending the Truss I manufactured by Drs S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a 'l russ for the radical cure of Hernia, I think it far preferable to any l have ever examined. LEWIS A. SAYRE, M. D. - Surgeon, Bellevue Hospital. From Prof. Willard Parker to S. D. Townsend, M. D., Surgeon to the Massachusetts General Hospital. T B EG leave to state for the benefit of āfi concerned, that I have known I Dr. S. N. Marsh the last fifteen years. * * I am in the constant abit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with any of the risks to the patient that exist in many of the plans suggested and attempted to be carried into execution. I have confidence in Dr. Marsh as a gentleman of honor and integrity, and as such recommend him to the members of the medi- cal profession generally. WILLARD PARKER, M. D. Professor of Surgery, New York City Dr. S. N. Marsh's Patent Radical Cure Truss, and all other kinds of Trusses Shoulder Braces, Supporters, Elastic Stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Cure Truss Offices of S. N. MARSH & CO., No. 2 Vesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. OPPOSITE THE HIGH STEEPLE, F. E. SUIR F. E. S. WAYNE F. E. Suire & Co., WHOLESALE DBUGGDST3, INZL AL INT TJ E A C T TJ IF, I INT G- £Hemists AND f'HARM aceutists, \ CINCINNATI, OHIO. Have constantly on hand a full assortment of sye), ecºx) ox{UGS ANYO WOEXOXCXN Es, cºeryxxcAx. AxºpA}{A}^Us, TESTS, MEDICAL, GLASS WARE, &c., &c., p ‘s And solicits the patronage of the trade and profession. We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, Made in accord.ince with the U. S. P. and other recognized authori- ties. ETINIFD ANTO EARHC CHEMICA LS, Of the popular class of preparations known as H. T., IL& IIER, S, We manufacture a full line. Those of our make may be relied apon (Aſº being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. Bitter Wine of Iron, An excellent Chalybeate and tonic, Wine of Iron, &c. AGENTS FOR BULLock & CRENSHAw's Sugar-coated Pills and Granules. & Price Lists of preparations and of Sugar-coated Pills sent by Mail upon application. The long standing and well and widely known repu- tation of our house we offer as a guarantee for the reliability of our preparation, and the quality of the goods sold by us generally. * > ** DIVIDED MEDICINES, The Divided Medicine Comy, CINCINNATI, OHIO. The Company have the honor of bringing to the notice of the Profession, this NEW AND ExcEEDINGLY PRACTICAI, METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. . The Divided Medicines are prepared by FREDERICK KRAUS, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MORE. . The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every square will consequently contain accurately measured quantities. But not only SoDUBLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINES. Vº - ºy This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, ; : #. sh. 10, and even idoo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. - Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE TO SPOIL BY ANY LENGTH OF TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. - Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calls with good accurately dosed ! medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. For samples, Price Lists, and Agencies, address - . "Iso- 2ese, Or FRFDERICK KRAUS, Chemist and Druggist, Walnut Hills, Cincinnati, O. MR. FREDERICK KRAUs: CINCINNATI, February 15, 1871. Dear Sir—The specimens of your “ Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: - SULPH:M0 RPTIII....................... % grain in each square. AT&SFN: A CID..........................1-20 grain in each square. “ CfI [N INI .......................1 “ “ {{. CALOMEL 34 “ - 4 4 “. COPPER ....................... % {{ RESPECTFULLY Yours, E. S. WAYNE, Analytic Chemist T H H C T ITNTIC . 109 Vol. 2.] S A T U R D A Y, M A R C H 9, 1872. [No. 10. O R. I G IN A L A R T I C L E S. –-º-º-º- C O R P U L E N C E . . A Case IIIustrating its Treatment. BY J. L. CLEVELAND, M. D. This condition is either the result of over-feeding or perverted assimilation. Adipose tissue when in its normal proportion, beautifies the body and serves for purposes of utility and comfort; but when increased much beyond a given proportion becomes an element of deformity and a source of very great discomfort, etc. It is not always easy to draw the line of demarcation between corpulence as robust health, and corpulence as an expression of disease. It has been defined a disease “when it renders persons, from a deficient respiration, uneasy in themselves, and from the inability to exercise, unfit for discharging the duties of life.” This allows us much latitude, which is required in the nature of the case, since a degree of obesity that would be disease in one, might be health in another; age, physical vigor, temperament, some other features perhaps, extraneous to the condition, constituting the difference. How- ever well persuaded medical men may be of the fact that corpulence is a disease, it does not alter the popular regard in which this condition is held. Jack Falstaff was a jest upon this class, who are still fre- quently made the “jest of the world.” The Spartan laws regarded the corpulent as subjects for punishment: “Citizens who grew too fat were soundly whipped.” “Namilus, the son of Pohytrus, was brought before the Ephori, and his excessive corpulence was exposed to the public. He was moreover treated with perpetual banishment if he failed to reduce his body within reason- able dimensions.” g Obese persons suffer from a diminution of vital power, and an unfitness for muscular activity, they are short- Winded, suffering from bodily torpor and mental hebetude. Lord Chesterfield thought fat and stupidity convertible terms; and Shakspere speaks of the fat-witted: the fat boy of the ‘Pickwick Papers' is sleepy-headed. Dr. T. K. Chambers, from his observation of 38 per- Sons, whose weight varied from 224 to 504 pounds, came to the following conclusions: the bony frame-work is less massive than in the spare, indicated by the small- *ss of the hands and feet. The skin is usually fresh colored and thin; the respiratory functions present a *Versal and well marked peculiarity, namely, the volume of air they are capable of taking in and expiring from the chest is considerably less than the average quantity contained and expired by healthy persons of equal height. The vital capacity is diminished and less carbon is expired. Adipose tissue may be distributed generally, or unusu- ally developed in certain localities, as in the mammae of the female, or in the omentum, thus spoiling fair propor- tions as well as being a Source of discomfort: It is not often met with before 30, though in some cases there is a congenital tendency to it. The cause and pathology of corpulence may be arrived at by noting the facts given us by physiological research, concerning the effects of food upon the animal economy. It has been found that to keep the body in a healthy state it requires from 5 to 8 pounds of mixed food every 24 hours; that is from I-26 to 1-20 of the weight of the individual in solid and liquid food, (supposing the body to be in a normal condition). This amount is about in the follow- ing proportion; the so-called solid food from 2 to 3 pounds. Liquids from 3 to 5 pounds. This represents the amount required under ordinary circumstances. A state of inactivity requiring less, and during extra- ordinary exertion much more food is required. Further, in order to have a healthy condition of body, the food must be mixed. Custom and instinct point to this physiological fact. Neither man nor the lower animals can live on the nitrogenous elements (albumen, fibrin casein, gluten, etc.,) alone, in a short time they will sicken and die; nor upon the non-nitrogenous elements (sugar, starch and fat,) on these they will likewise waste away, and starve in the midst of plenty. Nature fortunately has not left us to Select these elements for food, according to physiological laws, but we find them already combined in perfect harmony to the demands of the animal organism, and it only remains for us to follow the unperverted instinct of appetite. This should produce the normal amount of fat; which in health is about 1-20 the weight of the body in the male, and about 1-16 the weight of the body in the female. In the excessive disproportion that we have in corpulence, we may in some cases apply some of the facts that have been elicited by physiological research with very great advantage. The steps to be taken are simply these: the elements which produce fat in the system having been determined, the patient will avoid those elements as far as possible. Too much non-nitro- genous food favors the development of fat, and interferes with the proper nutrition of the muscular tissues, hence we find that rice feeders, potato eaters and those who indulge in fermented liquors are often bloated in their appearance and become extremely fat, and are not capable of extreme exertion. “The brewers dray- man although he has the appearance of robust health, is not a good subject for a college.” His muscular tisssue has been encroached upon by the fat, and his power has been weakened by an undue quantity of the respiratory element. The negroes on the sugar planta- % 110 [MAR. 9, 1872. TIEI IET: C T I I INTI C. tions are said to grow fat during the sugar season. Corpulent persons are generally vegetarians. “There is a sect of Brahmins who pride themselves upon their obesity, considering it a sign of wealth, whose diet con- sists exclusively of ſarinaceous vegetables. Fotherigal states that a rigid vegetable diet produces fat more cer- tainly than any other method. Bears fed exclusively upon bread grow very fat. It is well determined that food rich in fat and starches, as oils, fat meat, greasy gravies, sugars, the farinaceous vegetables or fluids con- taining oil, as milk, or alcohol; and sugar, as beer, ale, and strong wines, favor the production of adipose tissue. Dr. Chambers thinks that defective sun-light may be an important agent in developing fat, and relates a case that seems to sustain the view. Though corpulent men are generally “surfeit swelled,” they are not always either large or gross eaters, but they are invaria- bly great water drinkers, taking large draughts. Some- times corpulence is hereditary, it is then much more obstinate to treatment. - From the above remarks the treatment of corpulence naturally suggests itself, viz., to avoid as far as possible those kinds of food containing fat, sugar and starch. These principles were laid down by Dr. T. K. Chambers and were adopted by Dr. Harvey, in the so-called Banting system, which attracted so much attention several years ago. Bearing in mind the requirements of the animal economy, it is evident that a treatment upon this plan cannot be exclusive, as disease and debility will be the result. The animal diet when rigidly adhered to is often followed by grave consequences, as disorders of the nervous system, feeble digestion, obsti- nate constipation, general sluggishness, and, after a time, evidences of mal-nutrition. A dietary based upon sound physiological principles requires careful selections and close observation as to the effect that is being produced, making the changes that each individ- ual case calls for. Hence the necessity of intelligent advice whenever this method is to be adopted. The following case which I will narrate, while it illustrates the views that have been taken, also shows the necessity of exercising great care. A professional man, 29 years of age, about six feet high, weighed Sept. 25th, 224 pounds. This amount of fat did not interfere seriously with his locomotion, but he felt ap- prehensive in regard to the future, as he found that his weight was steadily increasing; besides he found that he was suffering from great hebetude of mind; in the afternoon when he sat down to his studies he would fall asleep in spite of every effort; this was not on account of a large dinner, for he was a light eater. He was much annoyed by this torpid condition of mind, and could rouse himself to mental activity only by great effort. This was very annoying to him as he is a man of more than ordinary mental and physical energy, and is actively engaged in the duties of his profession. He had tried the “Banting plan,” but was compelled to leave it off on account of the obstinate constipation it induced. He was satisfied that there was virtue in the method for by it he could always succeed in reducing his weight. He requested me to arrange for him a dietary and give him whatever advice I thought his case called for. The bill of fare was based upon the ideas that have been stated. Animal food was chiefly recommended, the fatty varieties avoided being veget- ables containing sugar, starch or oil. Tea and coffee without milk or sugar. No malt or alcoholic liquors and water only as required. I ordered vegetable and animal food in sufficient variety, as I supposed, to supply the physiological demands of the body, limiting him only in the use of certain articles. The faithfulness and resolu- tion with which my recommendations were carried out, may be inferred from the following table. He weighed regularly once a week on the same scales for fourteen weeks; this is the record. 1st week Sept 25th, weighed 224 pounds. • 2d “ Oct. 3d, {& 220 & 4 3d & & “ 10th, {{ 216 {& 4th “ “ 18th, “ 217 ºt 5th “ “ 23d, {{ 218 & & 6th “ “ 31st, 6 & 213; “ 7th “ Nov. 7th, “, 213 {& 8th “ “ 14th, {{ 211 & & 9th “ “ 21st, “ 210 {& 10th “ “ 28th, {{ 207 & & 11th “ Dec. 5th, ( & 205 & & 12th “ “ 12th, & 4 200 {{ 13th “ “ 19th, & 4 196 {{ 14th “ “ 26th, & & 192 &&. Feb. 13th, of this year 6 & 188 {{ Accompanying the above table was the following note: “There is I should judge at least 7 pounds difference between the clothing I wore on September 25th and those I now wear. So that I can justly claim to have lost seven pounds more than the record shows, as the record shows the loss without considering the additional increase in the weight of clothes. I have in the mean- time enjoyed perfect health, until about a week ago when I contracted a violent cold which has been troub- ling me since. I am so well satisfied with the experi- ment that I shall keep it up and advise you from time to time.” The gentleman also states that the heaviness and dis- position to sleep which formerly so much annoyed him, has entirely disappeared and has been replaced by a feeling of buoyancy and an ability to work much more satisfactory. He has not been troubled at all with constipation and he finds that he is beginning to lose taste for starchy and saccharine varieties of food of which he was formerly very fond. This change in the physio- logical habit of the system was not brought about (as is apparent from the record) without some shock; he con- tracted a “violent cold” which has proved very obstinate. This condition of catarrh of the upper air passages from which he has been suffering, was induced in all proba- MAR. 9, 1872.] T EL E. c 1 INTI c. 111 bility by the physiological change that is being wrought. Besides I would suggest that fat, which has been with- drawn in a great measure as food, is not only a calori- facient, but protects from cold as a non-conductor by means of the subcutaneous layer that invests the body, and this is gradually being reduced by means of the treatment. - * It is evident that patients undergoing this form of treatment are liable to various complications regulated by their constitutional tendencies. It is also generally evident that under appropriate advisement they can hardly suffer any serious consequences. It is not likely that most cases would yield so readily to treatment as the one just narrated without any medical interference; in most cases it will be found profitable, in some cases necessary, to use adjuvant remedies of various kinds, the alkalies, laxatives, tonics, etc. But after all, perhaps the most serious obstacle in the way of the success of i this method will be found in the patients themselves refusing or at least failing to conform fully to the requirements of the method. —-º-º-º- SOLID FOOD IN TYPHOID FEVER. * BY SAM'L D. TURNER, M. D. Circleville, Ohio, Without entering into a detailed history of the changes in opinion on the causes, course and treatment of typhoid fever, it is sufficient to allude to the fact, that this disease to-day is recognized as one of self-limitation, having like the other fevers a definite duration, course and specific lesion. - This recognition of the unity of the disease has so far modified treatment, that the physician is now con- tented to guide where he formerly sought to control or arrest; to put his patient in the most favorable position for recovery and trust to the restorative powers of na- ture for cure. In nothing is this change more marked than in the use of food. It is clear to us now, that much of the gravity of the disease was due to imperfect nutrition. Starvation undoubtedly killed more than the fever. We now see that increased heat, delirium, exhaustive diarrhoea, emaciation, fetid breath, destruction of elim- inative organs were common effects of starvation and typhoid fever. - Guided then by better knowledge and more extended observation, all modern authors urge the necessity of supplying the patient with a sufficient amount of nutri- tive food. With an equal agreement, authors join in recommending that all food should be fluid and point out the great danger of aggravated diarrhoea and possi- ble perforation of the bowels from the effect of solid food. Flint, Wood, Watson Niemeyer, Aitken, Reynolds, Murchison, and others, all agree in condemning its use. It is with diffidence, then, that I express my dissent from this view, and were my opinion not backed by a successful experience of eighteen years of moderately active practice, I would be content to keep a becoming silence. But this experience has taught me that these dangers are imaginary and that the advantages of solid over fluid food in typhoid fever are as great as fluid food is acknowledged to be over the older practice of semi-starvation. . Solid food does not cause indigestion, does not irritate the stomach or bowels. Given before structural altera- tions of the mucous coat, before privation of food has in- terfered with proper discharge of function, say within the 1st week, the stomach recoverstone, lost appetite returns, food is thoroughly digested, diarrhoea diminishes and disappears, the feces become natural in quantity and quality, delirium subsides, fever and thirst abate, reso- lution of the infarction of Pyers glands takes place, the evidences of mucousinflammation pass away and instead of all the symptoms increasing in gravity with the con- tinuance of the disease and the necessity arising for supporting the flagging strength with large doses of alcoholic stimulants and beef tea, the gravest attack grows mild, with the restoration of appetite, and the patient passes into convalescence by such imperceptible gradations that in most cases it becomes difficult to say at what time the fever ceased. I have yet to see the case in which solid food has aggravated in any way a single symptom. Where this has been properly administered I have never known death from perforation of or hemorrhage from the bowels or from intractable diarrhoea. Unfortunately Ihave kept no record of cases and can give no exact statement of results. From memory and from a partial examination of my note books I cannot place the ratio of deaths to recoveries at more than one in twenty, probably less. Such candidly and very briefly is the result of what may be called preeminently the food treatment of typh- oid fever, not to the entire exclusion of medicines, but with the minimum amount of dosage. I do not wish to set up a claim of originality in this matter and will merely call to the notice of the medical profession a brief article by Dr. Hooker, written many years ago on this subject. I was then led by satisfactory experience to adopt his conclusions. Give the patient at his usual meal times—thus observ- ing the habits of the digestive system—a regular diet of roasted potatoes, buttered toast, broiled beef steak, game or any other digestible fresh meat well served and prop- erly seasoned. Give little or no fluids while eating. Encourage Salivation by thorough mastication. The patient at the commencement loathes food more than medicine and it requires a full explanation of the benefits to follow and some moral force on the part of the physician to induce him to swallow a few mouthsful, but with each repetition the difficulties grow less and a steady persistence of a few days—ordinarily within four II2 [MAR. 9, 1872. TIEEE CI.INTI c. —sees the patient ready to take his meals with relishing appetite. The case can then be left largely to the point- ings of nature. I have nothing to offerin regard to medical treatment. Systematic treatises on medicine of the present day mostly agree upon this. But, in passing, I cannot re- frain from heartily disapproving of Niemeyer's endorse- ment of Wunderlich's large doses of calomel. If this practice and semi-starvation are followed on the con- tinent, I can not wonder at the fearful mortality there. Living in a rural district, quinine in large doses is at first administered. This not only clears up the diag- nosis but has a modifying effect upon the febrile action; an opiate to cheek early and profuse diarrhoea and pro- cure rest, and in graver cases of blood contamination, iron and chlorate of potassa, and sometimes stimulants, are indicated until the stomach recovers tone enough to digest natures only reliable stimulant—food. And then regimen and time. ———-º-º-º---—— $CHENTIFIC NOTES, $FIGNS OF D9EATH Johann Ludwig Casper, in his exhaustive work on Medical Jurisprudence, after referring to Frank's state- ment regarding the ease with which the conjunctiva may be separated from the cornea and to Larcher's black spot on the sclerotica, as scientific curiosities, says, em- phatically, that the well known signs of death are fully sufficient for a diagnosis. He enumerates the following stages between death and decomposition. 1. Respiration and Circulation have ceased. 2. Immediately after death the lustre of the eyes dis- appears. Who has not, he says, on raising the lids of a deceased person, noticed that peculiar, lifeless stare, which cannot be described ? Light, of course, has no effect on the pupils. 3. A reaction cannot be brought about by any means, in any part of the body. We say nothing, here, of the experiments with electricity, because they do not prop- erly helong to this subject. 4. The entire body grows pale. Still, persons that had, in life, a marked florid countenance, retain a good deal of color for many days after death. So, too, the red or livid margins of tumors do not change to the pale color of the corpse. Nor do the red, black or blue marks, made by tattooing disappear. Again, if there was present, at death, an icteric color, it does not change to white; and, finally, all marks of blows or bruises re- tain the color which they had at death. 5. The animal heat which existed at death, is retained for a time, because the cellular tissue is a poor conductor of heat. This is especially true of fat corpses, which, ceteris paribus, remain warm longer than those that are lean. But, in general, there are other circumstances, which is soon followed by other symptoms. that influence the retention of animal heat, such as the temperature of the place where the corpse is, and the manner in which death was brought about. It is well known how soon corpses grow cold in water, which, even in the hottest of summers, is colder than the air. In privy vaults and heaps of manure, a corpse naturally retains heat longer. The same must be said of persons that remain covered with bedding, after death. Persons who died of suffocation retain the animal heat notably longer than others.--It may be laid down as a general rule that in the great majority of corpses, the animal heat as far as the sense offeeling is concerned, disappears in from eight to twelve hours. In experiments with the thermometer this time is, on an average, doubled. 6. Immediately at, and after, death there occurs, also, a general relaxation of the muscles, the earliest symp- toms that prove the extinction of the turgor vitalis, and A corpse that shows only the signs enumerated (1 to 6) may be re- garded as that of a person who has been dead for from ten to twelve hours. - 7. A valuable proof of the extinction of the turgor vitalis is furnished by the softening and yielding of the eye ball. This may be distinctly noticed, in all corpses, after a lapse of from 24 to 30 hours; sometimes sooner, whilst the living eye ball resists the pressure of the finger under all possible circumstances, even in patients attacked with cholera and in persons just dying; in from 24 to 30 hours after death this resistance has ceased. The bulb yields, becomes soft as butter, until at an early stage of decomposition it bursts and pours oat its liquid. 8. The same cause, i.e., the extinction of the turgor, brings gradually about the well known flattening of the muscles in those parts on which the corpse lies, not only, therefore in the buttocks and calves, but also in the lateral portions of the upper and lower extremities, the cheeks, the anterior portion of the thigh, etc., accor- ding to the position in which the patient died or which he retained after death. 9. Hypostases, the result of the subsidence of the blood in the capillaries, according to the law of gravitation. They are, for this reason, found on the entire posterior (inferior) plane, the back, the nates, and the calves; but frequently, also, in the face, on the ears, on the lateral portions of the breast and the extremities. It is plain, therefore, that all hypostases may and do occur also on such unusual anterior and lateral portions of the body as the anterior region of the stomach, etc.; and in such cases we can determine, with a great degree of certainty, the position in which the deceased must have been, at or soon after, death. These hypostases become visible on the corpse, in from 6 to 12 hours after death, in rare cases even before that time. They gradually increase in extent until decomposition sets in. They are, in themselves, a perfect sign of real death. We must distinguish exterior from interior hypostases. - MAR. 9, 1872.] TIEEE IEH C T , I INTT C. 113 Eacterior Hypostases. Hypostases of the sub-cutaneous cellular tissue. Todtenflecke (death spots) constitute a significant symp- tom of death. The unskilled are in danger of confound- ing them with the marks of bruises, blows and the like, from which, however, they may easily be distinguished by incisions. An incision with the scalpel, in a Todten- jleck, will never reveal diffused liquid or coagulated blood at the base of the incision, at most a few small points of blood caused by several cutaneous veins, whilst an incision in the very smallest mark of a blow , or bruise is followed by a diffusion of blood. This being an infallible, and the only, diagnostic means of distinguishing exterior hypostases from the marks of blows and bruises, it ought never to be neglected. The color of exterior hypostases differs little from that of the crawfish, of copper or a bluish-red. As may readily be understood, they are never in the least ele- vated above the cuticle. Their form is very uncertain, sometimes striped, sometimes round, in other cases an- gular. At first they are found only here and there on the corpse, of the size of a walnut, an apple, or a dinner plate, until, gradually, they become confluent and cover entire portions of the body, such as the half of, or the entire back. Age, sex, constitution and the mode of death, have no influence on their formation; they are found even in cases of death caused by an excessive loss of blood. - - Interior Hypostases. These occur more especially in the following organs: 1. In the Brain. Here their presence is evinced by a fulness of the veins of the pia mater, which, in cases of a general abundance of blood in the cavity, is yet notably more marked than usual, and, in cases of anaemia, may still be easily seen. These hypostases of the brain occur even in cases of death from loss of blood. It is important not to confound them with hyperaemia of the brain (apoplexy) 2. The most constant interior hypostasis is that of the lungs. Orfila, says it becomes visible in from 24 to 86 hours after death; but it occurs really much sooner and at the time when a subsidence of the blood takes place in all the other parts of the body. The entire posterior of both lungs, about one-fourth of the complete parenchyma, is, in corpses lying on their backs, of a much deeper color than other portions, and an incision in the lungs, even in cases of aaaemia, reveals a notable fullness of blood. This is so remarkable, that the un- skilled are easily led into errors of diagnosis as to the Cause of death, e.g., apoplexy of the lungs, pneumonia, etc. This will especially occur where the blood is very dark and in cases of more or less cedema of the lungs. 8. Among the organs of the abdomen, hypostases occur, generally, in the intestines, and in the kidneys. They are quite common in the intestines, especially in the portions located in the pelvis. The bluish-red color of the inferior portion can deceive only the inex- perienced. The difference between places reddened by hyperamia and inflammation is shown by the color, the absence of lustre and by the location. 4. In the kidneys we find hypostases, principally at the posterior half, in cases where the corpse has remained on its back. They are, therefore, easily distinguished from a general plethora of these organs. - 5. The hypostases of the medullary substance of the spinal cord, has, up to the present time, been scarcely noticed, and yet it is important, because it too, may lead to errors of diagnosis. It is shown in the veins of the pia mater, and is the more frequently mistaken for meningitis as its occurrence is almost unknown to those engaged in the examination of corpses, because of the difficulty experienced in opening the spinal cord and the consequent rarity of such an operation. The novelty of the case easily misleads to the assump- tion of inflammation especially when it is known that the back has been subjected to acts of violence. The truth of this assertion may be readily demonstrated by examining a corpse that has lain on its back for some days, with reference to this hypostasis. Coagulation of the blood after death. 6. The heart is not subject to hypostasis. Still, the heart, more than any other organ or vessel, presents in the so-called polypi of the heart, a sign, which is of great importance in forensic diagnosis. It is expedient, therefore, to notice them here. These polypi are, as is well known, simply coagulated blood. That this coagu- lation in the heart sometimes takes place even before death, we may admit in cases where the death agony is of long duration, but certain it is that in the vast majority of cases it does not occur until after death, during the gradual escape of animal heat. Bockf and Donnét even go so far as to fix the time when this co- agulation commences at about four hours after death, but this can, at most, be considered only as the average time, for the tendency of the blood to coagulate varies according to its concrete quality. Hoppet hästlemon- strated that ceteris paribus, the coagulation of the blood will be accelerated, when it is thin and watery (hence the rapid coagulation after loss of blood and in cases of hydraemia) and that it will be retarded wheti it is deficient in oxygen and rich in carbon. Now, since it must be admitted, that the blood does not co- agulate all at once and simultaneously with death, but that it requires a certain time to go through the pro- cess of coagulation, it is clear that the doctrine that the blood, after death, can no longer coagulate, which is so often repeated, and was quite recently defended by Tardieu, is not correct, and the assertion that, because f Gerichtl, Sectionen, 4 Aufl. Leipzig, 1852, 5, 19. I Donné, Cours de Microscopie, p. 52. + Hoppe Seyler, Hdbch. d. Chem. Analyse, Berlin, 1865, p. 300. t Tardieu, Etude medico-legale sur l'infanticide, Paris, 1868, p. 71. 114 [MAR. 9, 1872. T THI EH C T , T N T C . the blood at the base of a wound is found to be coagu- lated, therefore, this wound must necessarily have been inflicted before death, cannot be maintained. Cadaveric rigidity. 10. The last sign of the earliest period of death, and which always precedes the first stages of decomposition, is cadaveric rigidity; the well known shortening and thickening of certain muscles, especially of the flexors | and adductors of the extremities, including the fingers and the lower jaw, which causes them to feel hard and firm. It begins in the neck and lower jaw, extends, subsequently, to the muscles of the face, throat, breast and upper extremities, and finally, the lower. This rigidity disappears in general, in the same manner, and after it has once disappeared, it does not occur again, but the corpse becomes flexible as before. Cadaveric rigidity commences, as a rule, in from 8 or 10 to 20 hours after death; in rare cases, sooner. Caspart says that in one case he noticed cadaveric rigidity of the lower jaw in 24 hours after death, and of the arms in 63 hours. It is necessary, therefore, to be cautious in determining the time of death. This rigidity may con- tinue much longer than from one to nine days which is the usual time. It seems to be certain, that in cases of narcotic poisoning it is either feeble or only of short duration. Tourdes” who examined two persons, killed by lightening, speaks of rapid and general rigidity, in both cases. In the immature foetus, mature neo- nati and small children it is comparatively feeble and of short duration. Caspar denies the statement of Som- mer that this is also the case in the aged. He considers it an error to maintain, as is often done, that in cases of death from suffocation, this rigidity does not occur at all, or at a later period or only for a short-time; they do not differ from ordinary cases. That a low temperature and alcohol favor a longer duration of rigidity, cannot be doubted. Caspar noticed it in several cases of death during intoxication as late as the fourth, seventh, eighth, and even ninth day, - Where the rigor-mortis is of longer duration, it is not uncommon to notice, in connection with it, discoloration caused by decomposition. An advanced state of decom- position alone does not, therefore, put an end to it. That it is in no case ever entirely absent, seems to be well established. The rigor mortis cannot well be con- founded with the rigidity caused by freezing. A frozen corpse is as stiff as a board, from head to foot, whilst in rigor mortis the extremities are, especially in the joints of the elbow and knee, still susceptible of some degree of flexion. A corpse that presents only the signs before enumerated (1 to 10) may be taken to be that of a person who has been dead at most two or three days.f f Caspar, Hdbch. d. gerichtl, med. Berlin, 1871, p. 27. *Tourdes, relation médicale de l'accident occasionné par le foidre, 8trasbourg, 1869. #Caspar p. 30. In order to accurately determine the time of death, it is of course, necessary, to have a correct knowledge of the various stages of the process of decomposition, but, the present article being already of sufficient length, and having, moreover, given an accout of all the signs necessary to determine death itself, we will defer the rest of the subject to a future time. Cincinnati, March, 1872. Henry Haacke —-º-e-º- G O A L ID U S T IN T H E L J N G S. Anthracosis Pulmonum (Stratton), The Coal or the Miner’s Lung. EY DR. LUDWIG HIRT, (Breslau). A Chapter selected from the Author's work on “The Diseases of Labor- ers from the Inhalation of the Manufactory Dusts” (Die Staubinhala- tions Krankheiten, Breslau, 1871.) Continued from No. 9. Concerning, then, first, the relative frequency of phthisis, we discover that of the 39.879 patients of Upper Silesia, 345, i.e., 0.3 per cent. only were affected. Of the 11,499 of Hörde, 129, i.e., 1.1 per cent. were patients with phthisis, while of the 49 miners, patients of our hospitals, only one was a sufferer from this disease. Of the 23 cases treated by Vernois, three are registered with phthisis. These results, with perhaps the single excep- tion of the last, are in gratifying accord with each other and establish the fact that of 100 patients among workers in coal, one, at most, 1.5, suffer with pulmonary consump- tion, a percentage as low as could have been hoped for. This conclusion gains in value and interest when it is remembered that it is confirmed by the observations and statements of different authors; all doubt is thus. relieved. Lewin, in his highly rational investigations —though mostly from small numbers it is true—arrives at the same result. Seltmann in his work on anthracosis expresses himself in the same sense and in Lombard's table, representing the frequency of phthisis in some 60 different trades, this disease falls among charbonniers to the 58th place This remarkable fact only meets its full appreciation when this percentage just given is compared with that derived from other “dusty” avoca- tion and from avocations free from dust. The frequency in which the disease under discussion occurs in other “dusty” avocations, whether the dust be organic or in- organic in nature we have already exhibited in a pre- vious page. A single glance at the table referred to suffices to demonstrate that no comparison at all is ad- missible as the frequency of the disease in the other MAR, 9, 1872.] “dusty” avocations surpasses that of the coal worker ten to twenty fold and more. Further comparison teaches us also that, even among laborers exposed to no dust inhalation in their pursuits, this disease is much more frequent, and now follows the most remarkable fact in these observations to the effect that the per- centage of phthisis is greater in entire populations than in laborers exposed to coal dust inhalations. The entire population of the Upper Silesian Verein is 148.429; of these 345, were consumptive, i.e., 2.3 in every 1000; we have seen alreadyi that it is only in a few selected places (St. Helena, Algeria,) that the percentage is but 2.5 while every where else the number of deaths in a thousand is three to four, almost double, thus the per- centage of our list. These facts from the Verein almost confirm to a cer- tainty the hypothesis that coal dust is far from ever being causative of consumption; that it is in this respect not to be compared with other dusts; that it in all probability pos- sesses the property of preventing the development of this dis- ease, of restraining it, more especially, in its further course. To illustrate these facts more clearly the following tables have been prepared in exhibition of the percentage of consumption among laborers, patients with internal dis- eases, embracing those who have inhaled inorganic and organic dusts, those from pursuits free from dust and those, finally, subjected to the inhalation of the dust of coal. Of 100 Patients Affected with Phthisis. Laborers inhaling inorganic dust about 26 per cent. & 4 & 4 organic & 4 § { 17 & 4 & & i. Ilo & 8 & & Il & 4 & 6 & 4 coal 4 & 4 4. 1.3 & 4 The statement of Guillot that he always found tubercle in the lungs of consumptive patients calcified, chalky —in process, thus, of cure—when much coal had been deposited (which chiefly takes place in the apices) affords an anatomical explanation to the peculiarity, already mentioned as pertaining to coal dust. In what manner the calcification of tubercle is brought about as the result of coal dust inhalation, whether coal acts as an antiseptic or whether it prevents the development of the vessels, which, according to Schröder van der Kolk, are always observed about tuberculous deposits, is a question that may not yet be answered. The fact that it was formerly believed (and even now this belief if often encountered): that coal dust develops consumption depended on the confounding of this disease with the above described anthracosis which in its latter stages sometimes runs a Course common to consumption; that these affections, however, are quite different from each other needs no further emphasis than a reference to the first section of our subject. As to the frequency of anthracosis among workers in TIEHI E C T , T N T C . 115 coal it is difficult, unfortunately, to make any definite Statements, because it remains often enough entirely or almost entirely without symptoms during life, when it is revealed only on section. In all probability all coal Workers suffer with it in light grade; grave cases are rare or at least are only rarely observed. Statistics are wholly wanting. The following table exhibits the relative frequency of chest affections among workers in coal. Of 100 Patients Affected with Chest Dis. Coal work- | Phthisis. | Chronic ] Emphy- Pneumo- || Total. erg. | Bronch. I sema. Inia. Upper Silesia.f 0.8 16.4 0.9 4.7 22.8 pr. ct. Hörde.t 1.1 18.3 ? 3.6 23 “ Parist º 69 17. 2 7 7 Breslau.” 2.0 22.4 8.1 14.4 46.9 F- While as we have seen in this portrayal that a large quantity of the coal dust which impregnates the labor- ers atmosphere is inhaled and penetrates the organs of respiration there is still another quantity which takes another course in the economy, being swallowed by the laborer into the Organs of digestion upon which it exer- cises an influence. That this influence, too, has been over-estimated hitherto is now without doubt. Rama- zinni, for instance, was Sorely afflicted with the belief that coal dust excites in the stomach an afflux of fluids and a preternatural sensibility, that it disturbed (?) the function of digestion and , thus laid the foundation for occlusion of the intestines, for the cachexia carbonica. Though it may not be maintained that the influence of coal dust upon the organs of digestion is entirely null yet we are certainly not justified in accepting the grave fears of the above mentioned observers. Coal dust in- duces, when accumulated, in mass, in the stomach of laborers, not accustomed to it, loss of appetite, light gastric catarrh, constipation and black discoloration of the feces. Long consuetude diminishes or dissipates the first mentioned inconvenience, leaving only a chronic obstinate constipation. Graver diseases of the abdom- inal organs in consequence of coal dust, more especially a cachexia from this cause are cases in rarest exception and even then may be predicated to a series of other predisposing and concurrent circumstances. As to the frequency of the diseases of the text we discover from the observations referred to that they occur among coal workers neither more frequently nor more rarely than among other laborers, since of the 39,879 patients of Upper Silesia, 5,531, i. e., 13.8 per cent., and of the 11,499 patients of Hörde about 14 per cent. suffered from gastric and intestinal catarrh. Similar, at least foesterlrn, Handbuch, etc., p. 375. #Total number examined 148.429. Total number patients with in- ternal diseases 39,879. tTotal number sick 11,499. fTotal number examined 255, patients 23. *Total number patients 49. 116 [MAR. 9, 1872. TiE E C T.I. NI c. but very little different, results are gleaned from the statistics of laborers in avocations free from dust. Though we may not, then, in conclusion, claim that a few inconveniences and light abnormities may not re- sult from the ingestion of coal dust, yet it can no longer be admitted that serious life or even health threatening diseases of any duration ever ensue from this cause. The relative frequency of disease in general, the aver- age duration of life and the mortality of coal workers will engage us when we come to speak of the different avocations which coal affords. For a general view of the influence of coal dust upon laborers the statistics just tabulated suffice; they embrace the diseases of most importance and of most frequent occurrence. They teach us, what is confirmed by a glance at the tables of other dusty avocations, that coal dust is not only the least injurious of all the various dusts, but also that there are conditions connected with its inhalation which exercise an unmistakeably beneficent influence upon the laborers health. After these general considerations there remains only to be considered the different trades which are worked in coal ; as already stated our lists afford us but few numbers from which to draw conclusions, embracing only 49 workers in coal and 76 chimney sweeps. Con- cerning first, the general frequency of disease—and here coal cart-men, coal shovellers and workers are included —it is to be remarked that this is extraordinarily low notwithstanding the fact that the labor of the first mentioned class is often extremely severe. According to Lewin, of 160 cartmen, 108, i. e., 67.5 per cent. were perfectly sound at the time of the examination; of 58 whose service had extended from 5-10 years, 34, i. e., 58.6 per cent. were perfectly healthy; of 45 whose ser vice had extended longer than 10 years, 51.5 per cent were sound. Shovellers and workers showed an even better condition, the results of examinations being ex- tremely favorable. In full accord with these results are those derived from the examination of chimney sweeps. Here too, the frequency of disease, as we dis- cover from Lewin, is extremely low. Of 45 boys exam- ined, 39, i. e., 84.6 per cent. were sound. After a ser- vice of 5-10 years 50 per cent. were sound, but after a service of over 10 years 92.3 per cent. were sound. This last statement, viz., that after 10 years almost all were healthy, would go to prove that coal dust is not only not injurious but is absolutely conducive to health; the numbers concerned, however, (only 36 sweeps) restrain us from further deductions. Of other pursuits which have much to do with coal dust, but which unfortunately do not occur in our lists, we may mention the moulder, the influence of whose labors has already been subject to such wide discussion and strife. The strewing of the ready ſorms with coal dust, the blowing away of the superfluous dust, these are the manipulations which have been considered as of such extreme danger to health. Yet, according to quency of individual diseases. Lewin, the frequency of disease is very slight among these laborers. Of the men examined 81.4 per cent. were healthy; after 5–10 years service 72.7 per cent.; after more than ten years 51.5 per cent. These numbers must certainly be discouraging to those who have been crying so long and loud for protective measures for moulders against the injurious effects of coal dust. Let us pass now to the investigation of the relative fre- The list for the workers in coal has already been exhibited; it has been shown that of 100 patients, 46.9 per cent. suffered with some form or other of pulmonary affection; of these 22.4 per cent, almost half, was bronchial catarrh, while phthisis claimed only two per cent. In chimney sweeps, now, We find that 41.8 per cent. of all diseases are chest affec- tions; of these bronchial catarrh takes 22.2 per cent, phthisis 6.5 percent. That this last disease occurs here three times as often as among other workers in coal is explicable not only by the fact that the labor is ex- tremely, even exhaustingly severe, but that the con- stant, unavoidable change from the warm chimney to the icy roof exposes them to frequent colds. These same circumstances may be evoked also in explanation of the relatively greater percentage of pneumonia (10.5) and of acute diseases in general (39.4) among this class of laborers. Among the firemen in manufactories, lung inflammations also frequently occur, not from the inha. lation of dust, but from the frequent change of tempera- ture. As to emphysema it plays but an insignificant role (2.6 percent, of all diseases) among chimney sweeps, While we find it noted at 8.1 per cent. among other coal Workers. This is a difference of difficult explanation. The last percentage given, 8.1, can hardly be considered reliable as we find that in the lists of Upper Silesia, emphysema holds a quite low place in percentage (0.9). This, as will be observed, is more in unison with that just given for chimney sweeps. The condition of health of colliers (charcoal burners.) was studied by the author in the neighborhood of Wal- denburg, in Austrian Silesia. A large number of kilns are built there whose presence is recognised at a great distance in consequence of the peculiar odor which they generate and diffuse. The colliers who are exposed continually to the influence of charcoal dust complain in general, but little. The effect of the dust is, of course, considerably relieved by the fact that they work in the open air where the wind is the ventilator. Even if charcoal dust possessed a decidedly injurious influence these laborers are still in a relatively favorable condition. Any injurious consequences from this dust inhalation is scarcely or not at all d e monstrable. Consumption belongs to the rarities i Pneumonias are observed no oftener among the laborers than among the other inhab- i"ance of the place. These statements, it is true, are j Concerning the relative frequency of anthracosis, there is as yet, but little to state. Black expectoration is not rare, but it is usually only temporary. Autopsies are strongly forbidden in the region visited by the author. MAR. 9, 1872.] not deduced from strict statistics. How may, indeed, such facts be established among a people who are not in the least interested themselves? The above statements, however, as to the frequency of consumption and pneu- monia rest upon perfectly reliable communications. As to other diseases, like the average mortality rate, but little reliable could be gleaned. The average duration of life is from 58–60 years. Compare Ramazzini, Patis- sier's revision, p. 10. n T As to the mortality rate we gather sufficient informa- tion from the annual report of 1851. Of 10,628 workers in coal, 160, i. e., 1.505 per cent. died ; of 9,741 shovel- ers [händlern], 140, i. e., 1.520 per cent. died; of 4,146 chimney sweeps, 95, i. e., 2.291 per cent. died. The least percentage was that from the cartmen busied in open air with constantly changing work; less favorable was that from those engaged in magazines, and most unfavorable was that from the hard working, often ex- posed, chimney sweeps. LITERATURE. Beddèes, An Essay on the Causes, Early Signs and Pre- vention of Pulmonary Consumption, London, 1801. Ramazzini, Patissier's Revision, p. 9, Ilmenau, 1823. Marshall, Lancet, Phthisis melanotica, 1834. Fuchs, tiber das Kohlenbrennen in Meilern in med- polizeilich. Hinsicht. Henker's Zeitschr. f. Staatsarzneikunde 17 Jahrg., 1837, Ergänzungs- heft, p. 12, et seq. - Schönfeld M., de l’état hygiènique et moral des ouvriers-enfants, employés aux mines de char- bon dans le district de Charleroi, Charleroi, 1843. Küpper, Krankheiten und Gefahren, welche den Bergmann in den Steinkohlengraben bedrohen, ^. Rhein und Westphal. Correspond. Bl, No. 17–23 1845. - Holland, Inhalation of gritty and metallic particles, Monthly Journ., Nov., 1843. Holland, Diseases of the Lungs from mechanical || causes, London, 1843. e Makettor, An Investigation into the Nature of the Black Phthisis, Edinburg, 1846. Brockmann, die Metalburgischen Krankheiten des Oberharzes. Osterode, 1851. Bartheleness, Diagnosis der Lungen Erlangen, 1855. Tardieu, Étude hygiènique sur la profession de mou- leur en cuivre, Paris, 1855. Cox J. W., Diseases of Coal workers and their causes, Journ. Pub. Health, Mar., 1857. François, Ueber Immanität der Steinkohlenarbeiter gegen Lungen Phthise, Presse méd. 43 und Bull. de l'Acad. de Belge, 1857. Maggiorani, Sull' ingresso dellasubstanze pulverulente nella via della respirazione, 1858. Vernois, Ann, d'hyg. 2 sér. ix. p. 844, Août 1858, melanosis TIH. H. cI.I.INTI c. 117 Fossion, Bericht tiber die Krankheiten der Arbeiter in der Steinkohlengruben, Bull. de l'Acad. de méd. de Belge, 8, 1859. Heszay, Krankheiten der Bergleute zu Hodritsch, Ungar, Zeitschr. II, 33, 1859. Schönfeld M, Recherches sur l'état sanitaire des houilliers, etc. Mém. pub. par l'Acad. royale de med. de Belgique, Tom. II. Bruxelles et Charleroi, 1859. Marten, die Schädlichkeiten and Krankheiten, denen die Kohlengrubenarbeiter unterworfen sind. Vierteljahrschr, f. ger. Med. XVI, Oct., 1860. “ zur med. statist. Geschichte der Hermanns- hütte zu Hörde, Pappenheim's Beiträge zur exacten Forschung, etc. Heft I, 1860. Reimbault, Hygiene des ouvriers mineurs, etc. Paris, 1861. - Böens Bosseau, Traité pratique des maladies, etc., des houilleurs, Brux, 1862. Villaret, Cas rare d’Anthracosis, etc. Paris, 1862. Perroud, de l’état charbonneux du poumon, a propos de quelque fait graves d'anthracosis. St. Etienne, 1862. Robers, C, De la phthisie charbonneuse et suivi de quelques considérations Sur la pénétration des corps pulverulentes et sur l'absoption des matières solides, Paris, 1862. Kuborn, Etude, Sur les maladies particulières aux ouvriers mineurs. Paris, 1863. Wilson, Customs and Diseases of the Miners of Dur- ham and Northumberland—Med. Times and Gaz., Oct., 17, p. 384, 1864. Friedriech, Virchow's Archiv. xxx, p. 394, 1864. Beaugrand, Sur la Santé des mineurs, Canstatts Jahresber, 1865. Lewin, Die Inhalations therapie, Berlin, 1865, p. 24, et seq. Seltmann, Die anthracosis der Lungen bei der Rohlenbergarbeitern, Deutsch. Arch. f. Klin. med. Vol. ii, p. 300, 1865. Zenker, tiber Staubinhalations Krankheiten, Deutsch. Arch. f. IClin. Med. vol. ii, p. I16, 1867. Vleminckx, Bulletin, etc., 1869. Tom. III, 12, p. 1249. º Schönfeld, M. Nouvelles recherches sur l'état sanitaire, moral et social des houilliers, Charleroi, 1860. Rindfleisch, Lehrbuch der patholog. Gewebelehre, 2nd Ed., p. 375, et seq., Leipzig, 1871. Merkel G. Zur Casuistik der Staubinhalations Irank- heiten, Deutsch. Arch f. Klin. Med. Vol. viii, p. 206, et seq. LAUGHING.-Rausius Texter, a French writer who flourished in the beginning of the Sixteenth century, gives a list of persons who died laughing, but he seems to doubt whether laughter ever causes death. It is stated that prolonged tickling of the soles of the feet is employed as a torture by the Chinese, the victim at length dying from exhaustion; and there was a vague Statement some forty or fifty years ago, of a man being tried for murder by tickling three wives to death. 118 [MAR. 9, 1872. TIEEE TED CT, ITN T C. Books and Pamphlets Received. NEUMANN's HAND Book of SKIN DISEASEs. Trans- lated by Lucius D. Bulkley, A. M. M. D. 60 wood cuts. New York, D. Appleton & Co., 1872—Geo. E. Stevens & Co. A PRACTICAL TREATISE ON THE DISEASES OF WomeN. By T. Gaillard Thomas, M. D. Third Edition Revised and Enlarged. Philadelphia, Henry C. Lea, 1872. Robt. Clarke & Co. Price $600. SEVENTEENTH ANNUAL REPORT of the Board of Trustees of the Southern Ohio Lunatic Asylum at Day- ton, for the year 1871, Columbus, 1872. PEPSIN–New Practical and Reliable Method to Pre- pare it, by E. Scheffer, Phila., 1872. —sº- e-º--- Journal Changes, etc. § Reuben A. Vance, M. D., whose name lately appeared as editor, is no longer connected with The Medical World. The publishers, Wm. Baldwin and Co. have issued the February number and propose to continue it themselves. THE NATIONAL MEDICAL JOURNAL.—On account of a determination on the part of the publishers of this Journal to insert an article, which in the shape presented, was not deemed suitable by the editors, Drs. Busey and Lee, these gentlemen have retired from the charge of the Journal and the February No. will be issued under the entire control of the publishers. VERMONT MEDICAL Journ AL.-J. M. Currier, M. D., of McIndoes Falls, Vermont, will commence early in the year the publication of a Medical Journal under the above title. —º-O-ºsm-- CILINICAL MEMORAN IDA. Treatment of Sick-Headache Dr. Clifford Allbutt, of Leeds General Infirmary, be- lieves it to be of the highest importance that sick-head- ache, properly so-called, should be recognized as a neu- ralgia, but he also believes that among physicians there is no longer much ignorance on this point. These head- aches may, and often do, occur in persons who present every other indication of good health and vigor; but in them or their family there is generally found a history of some other neurosis, such as asthma, neuralgia of the stomach, trunk or limbs, insanity, bed-wetting, eczema, psoriasis, and the like.i. If this be absent, there is gen- #There is no doubt a curious connection between sick-headache and gout; but Dr. Allbutt thinks that this is not due to any common ground in abdominal congestion or diphtheria, but rather in the curious neu- rotic element which enters into the true conception of gout itself. erally some history of great mental strain during the earlier life of the sufferer. The only well-marked excep- tion to this rule which Dr. Allbut has noted is the occurence of sick-headache in connection with uterine or ovarian disease, and in these cases bromide of potas- sium is especially valuable. Generally speaking, how- ever, sick-headaches are not due to peripheral causes, though these may intensify them, as epilepsy may thus be intensified. A coated tongue and a bad taste in the mouth are often complained of by the patients, and by these symptoms both patient and physician are often tempted to a purgative treatment and to a lowering of diet, which is very injurious. In the intervals of the attacks a very liberal diet is required, together with mental rest and wholesome conditions of routine and of variety; and the disordered tongue and taste are, no doubt, to be regarded as of nervous origin. In hemi- crania, for example, both the bad taste and the coat are often confined to the side on which the pain occurs. If the attack set in violently and without warning, little can be done, even by the hypodermic use of mor- phia, to cut it short. If a stimulant, such as black coffee, be given, it must be at the very commencement; afterwards it will do harm. The patient must be placed in a darkened and absolutely quiet room, and must ab- stain from all but the very lightest food till about 5 P.M., when the attack generally relaxes, and a mutton-chop may be taken with advantage. Dr. Allbutt thinks that sick-headache is substantially the same affection as hem- icrania, for every transition may be traced between the two, hemicrania in the majority of cases wandering be- yond its proper limits. Hemicrania he believes, with Anstie, to be a neuralgia of the fifth nerve; hence the injunction to avoid food during an attack is borne out by the well-known experience of asthmatics, who find that food in the stomaclu, probably by setting up irrita- tion in the vagus root, intensifies the paroxysm; in the same way the presence of food in the stomach during a paroxysm of sick-headache seems by the intermediation of the vagus to disturb the morbidly irritable root of the fifth nerve, which lies near its own. In the same way, Dr. Allbutt regards the vascular changes as secondary, and due to a propagation of the irritation in the medulla to the vaso-motor centre contained in that part; he be- lieves that the vasal paresis described by other writers on the subject is but partially true, and that this paresis is preceded by a period of irritation shown by pallor, coldness, small temporal pulse, and dilated pupil. This stage is seldom observed, as it usually occurs be- tween 5 and 8 o’clock A. M., and is succeeded by the paresis of exhaustion, with its evidences in the flushing, full and soft temporal pulse, and contracted pupil. The tight handkerchief and the cool applications comfort, he thinks, by their sedative influence upon the terminal expansion of the fifth nerve, and not by affecting the vascularity of the head. Many persons have more or less warning of an approaching attack, such as a feeling of dulness in the head, odd tinglings in limited regions, MAR. 9, 1872.] TEL H. cI.I.INI c. 119 —; and the like. Such persons may avert an attack by the use of five to ten cells of a continuous galvanic battery, or by means of twenty to sixty grains of nitrate of ammonia. In the intervals he relies, in addition to the measures already mentioned, upon tonics, of which ar- senic is the first in value and strychnine the second, and upon the daily or tri-weekly use of the continuous cur- rent. In uterine cases, of course, attention will be given to the peripheral disorder.—Brit. Med. Journ., Jan., 13. THE RELATIVE VALUE OF THE QUININE SALTS.— The following are the points in a note read by Mialhe, at the meeting of Jan. 30, '72, of the Paris Academy, upon the relative therapeutic value of quinine salts: - 1. Sulphate of quinine ought not to be used as a basic sulphate, but as an acid sulphate; 2. Sulphate of quinine is one of the most active and efficacious of all the quinine salts; 3. The efficacy of the valerianate of quinine depends more upon the valerianic acid than upon the quinine. 4. The tannate of quinine is one of the least active and least efficacious of the quinine salts, though it is not entirely devoid of effect. M. Chauffard remarked that he did not regard the tannate of quinine entirely inert, but that it was much less powerful, much less active than the sulphate, and that the latter must always be employed in paludal intermittent fevers. M. Jules Guérin could not agree with Mialhe that the efficacy of the valerianate of qui- nine depended upon the valerianic acid. It is a salt of - equal energy to the Sulphate in affections other than || paludal fevers. For the latter he prefers the sulphate. M. Piorry regards the efficacy of the salts of quinine as being proportionate to their solubility. He thinks in this respect no preparation equals the alcoholized quinine, which is competent in forty seconds to bring about considerable reduction in the kidney. The sulphate of quinine, even when acid, acts much slower.—Gazette des Hopitaux, Feb. 1, ’72. —-º-º-º- | HIOM IE NEWS. Medical College of Ohio Fifty-First Annual Commencement. The exercises as announced were held in College Hall Friday evening March 1st, in presence of perhaps the largest and most select assembly ever gathered upon such an occasion in the history of Cincinnati. Within fifteen minutes after the beginning of the exercises there was not even standing room in the lower half of the hall and numbers were turned away at the door. The exercises opened with an appropriate Prayer by the Rev. S. M. Merril, which was followed by Remarks by Prof. Jas. Graham, Dean of the Faculty. The Dean Congratulated the Hon. Board of Trustees, his colleagues, the profession and the public on the continued prosper- ity of the college, a prosperity this session so far as the number and character of the students were concerned unprecedent in the history of the institution. The ma- triculating list registered 226 names; the graduating class numbered ninety. A handsome tribute to the energy and enterprise of the younger members of the Faculty followed which was all the more gracious in that it had been predicted by some of the feeble in cir- culation, that the transfusion of so much youthful blood would be attended with disastrous results. Nearly 2000 alumini had been sent out from the old walls of the college in her more than half a century’s existence, and the eminence to which many of them had attained was best exemplified by the fact that in this city alone, no less than fifteen professors in colleges and lecturers in hospitals held the diploma of the Medical College of Ohio. The degrees were conferred by the Hon. Flamen Ball, Pres’t. of the Board of Trustees, according to the time honored custom of the institution. GRADUATES. Wm. A. Adair, Ohio; J. B. Anderson, Ind. ; J. S. Baughman, Ohio; Thos. L. Brown, Ohio; Joseph A. Brumleve, Ills; Samual P. Brundige, Ohio; John Wm. Burnett, Ills.; John Campbell, Ohio; C. D. Carpenter, Ohio; John M. Carr, Ohio; Robert F. Carpenter, Ohio; Geo. F. Cook, Ohio; S. Crumbaugh, Ohio; J. J. Dailey, Ind.; G. D. Darnall, Iowa; John T. Davis, Ohio; R. T. Dean, Ohio; J. D. Dougherty, Ohio; J. T. Drake, Ohio; J. W. Duncan, Ind. ; Wm. T. Elder, Ohio; Ephraim M. Fine, Ind, ; Robt. L. Finnell, Ky. ; C. H. Foertmeyer, Ohio; John A. Frame, Ohio; Orville Gaddy, Ind.; W. M. Goodlove, Ohio; David G. Grier, Ohio; Wesley B. Guthrie, W. Va.; Wm. A. Hall, John W. Hays, Ohio; Andrew J. Hazelwood, Ohio; E. E. Hughes, Ohio.; Allen Hussy, Ohio; Frank Hutchings, Ind. ; Chas. B. Johnson, Ills. ; Jas. John- son, Ills.; E. King, Ky., John A. Kroeger, Ills.; Fred- erick Langenbeck, Ohio; D. M, Lewis, Ohio; Samuel J. Lisman, Ind. ; J. M. Lockhart, Ohio; John M. Lyle, Ohio; A. A. Mannon, Ills.; R. Y. Martin, Ind. ; Abijah P. Mendenhall, Ind.; Leonidas Mason, Ind.; E. B. Miller, Ind.; Wm. E. Moore, Ohio; Winfield S. Marshall, Ills.; H. G. McAllister, Ohio; John S. McBean, Ohio; Josiah McKechnie, Ohio; B. B. Morgan, Ind., T. Goodloe Morrison, Ky. ; Noah D. Myers, Ind; John H. Nichols, Ohio; G. G. Parker, Ind., E. W. Parker, Ohio; John W. Piper, Ohio; I. Nutt Plummer, 120 [MAR. 9, 1872. T IEEE IET: C T , T INT I C - Ind. ; U. C. Prather, Ind. ; Robt. C. Prewett, Ills.; R. E. Pryor, Ohio; James B. Ray, Ohio; L. M. Reamy, Ohio; B. S. Rice, Ky., J. V. Bichardson, Ohio; A. W. | Ringer, Ohio; J. Thornton Robinson, Ohio; James H. Roll, Ohio; J. B. Rosson, Ills. ; Darious Rowe, Ohio; E. D. Snyder, Ohio; Willis E. Sutton, Ind. ; Amos Taylor, Ohio; James L. Taylor, Ohio; J. Smith Thomas, Ills.; Peter Thornton, Ky., M. W. B. Vickrey, Ind.; T. G. Vaughters, Ohio; H. C. Vincent, Ind., C. C. Walton, Ind. ; Amos H. Warner, Wis.; Albert A. Wells, Ky., W. T. Wells, Ind. Ad Eundem. DR. F. P. ANDERSON, (Miami Med. Coll. Cinti.) Ohio; DR. W. O. SMITH, (Transylvania Univ. Ky.) In Honoriam. E. S. Wayne, (College of Pharmacy, Philadelphia), Ohio. Total 90. Hon. Judge Whitman delivered the address on be- half of the Board of Trustees. The address was a half hour's sparkle on regular irregularities exhibiting in the language of a critic an intimate knowledge of the springs and actions of the so-called black arts in medicine with, at the same time, a hearty sympathy with all that is honest and true. Prof. Thad. A. Reamy closed the exercices with a valedictory address from the faculty. After the flow, the feast, at Dr. Dawson's until a late hour in the night. The music was fine, the speeches in good taste, the ban- quet worthy its host. The whole affair was a grand Sll CCeSS. The following gentlemen were elected internes to the Good Samaritan Hospital for the ensuing year as the result of the competive examination held last week: Drs. A. W. Ringer, John M. Carr, A. M. Lockhart. Service commenced this week. AT the recent election at the Academy of Medicine the following gentlemen were chosen officers for the en- suing year. Jas. Graham M. D. President, F. P. Ander- son M. D. Recording Secretary. Other officers, Vice Presidents, etc., were also elected but their names were not ascertained. DIED.—At his residence in Avondale, at five o’clock Friday morning March 1, of apoplexy, Israel S. Dodge, M. D., in the sixty-fifth year of his age. Dr. Dodge was a graduate of the Medical College of Ohio early in its history and has been for a long time an active member of its Board of Trustees. In his death Cincinnati loses one of her oldest and most respected citizens, and the medical profession a faithful and devoted servant. Medical College of ohio. S PR IN G C 0 U R S E, The regular eight weeks course of practical instruc. tion for the Spring of 1872 commences March 15. Un- usual advantages are offered this year in the fact that the course will be conducted by the entire Faculty of the College. • The course will embrace the following topics: Clinical Medicine—Bartholow. * “ Surgery—Dawson. - Anatomy Brain and Nervous System—Gobrecht. Operative Surgery—Conner. “ Obstetrics—Reamy. (£ Ophthalmology—Seely. Female Pelvic Surgery—Palmer. Urinalysis—Nickles. Physical Diagnosis—Cleveland. Fractures and Dislocations—Kearns. Genito-Urin. Dis.—Anderson. Microscropy—Whittaker. Prof. Graham will deliver occasional lectures on Clin- ical Medicine and Diseases of the Chest during the pro gress of the Course. The design of the Course is to present instruction in a thoroughly practical manner. Physical Diagnosis is to be demonstrated in the hospital wards; Operative Surgery, Operative Obstetrics, Operative Ophthalmology, and Operative Gynaecology on the cadaver. - The Dissecting Room will be under the supervision of Dr. Brown, where abundant material will be provided. Special attention will be paid to the chemical and mi- croscopical analysis of morbid urine. In order to render this course the most practical pos- sible, an opportunity will be. afforded each individual of the class to make the various examinations and opera- tions on the living and dead subjects. Regular daily Medical and Surgical Clinics will be held at the Good Samaritan Hospital: Two Daily Clinics will be regularly held in the Cincinnati Hospital, throughout the entire course; and a Daily Clinic will be held at the Dispensary of the Medical College of Ohio. One hour each evening will be devoted to Recitations on Anatomy, Physiology, Practice, Surgery, Obstetrics, and Materia Medica. - The eminently practical nature of this course, and its shortness of duration, together with the great clinical advantages presented in Cincinnati, can but commend themselves favorably to the practitioner as well as the student. . . . . FEES FOR THE ENTIRE Course, $10 As this Course does not count towards graduation, being considered supplemental to the regular winter course, graduates of the College are not required to matriculate. The matriculation of non-graduates is deducted from the fees of the ensuing winter session. Carriage Manufacturer, Nos. g and il East sixth Street, bet. Main & Sycamore. I MAKE NOTHING BUT - CºA, 2A S.S. W’62 ſº M'. Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of - LIGHT FAMILY CAFFIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very € X- tensive variety of light elegant designs of different cost and finish. In vehicles especially - PHYSECHANs' The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. * , - ) 6. The superiority of my light gentlemen's buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price lists furnished on application. References | to Dr. W. W. Dawson and all the leading Physicians in the city and neighborhood. S -msm-mate ||||||||||}|| MM|||}} ||M|| 167 EAST 34 TEI-ST., NE W YO RIC, By Special Appointment Electrical Instrument Makers tº the New York State Hospital for Nervous Diseases, MANUF ACTURERS OF PORTABLE ELECTRO-MAGNETIC MACHINES, Portable Galwamic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, 1870, and May 30th, 1871. These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery Fluid. |M|| |||||—|| || PERMANIENT EATTERIEs, For Hospitals and General Practitioners, IET ITECTIE, OTDIES. For Eye, Ear, Larynx, Nose, Uterus, Wagina, Bladder, Rec- tum, Feet, Phrenic and Sympathetic Nerves, Elec. trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. JEXTRA (!TS FROM THE O PINIONS OF THE MOST JEMIN ENT MEMBERS OF THIS PROFESSION. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “Nothing CAN EXCEED THE EFFICIENCY AND CONVENIENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” We are authorized by Prof. Hammond to announce en- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- roved and re-modified lnstruments made by our Company. * MEREDITH CLYMER, M. D., Prof. of Diseases of the Neº- vous System and of the Mind, &c., &c.—“I consider their Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prof. of Surgery, St. Louis:—“In neat- ness, compactness and efficacy, they can not be excelled.” ALFRED C. GARRATT, M. D., Boston :-"In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” Similar Testimonials have been received from JOHN J. CRANE, M. D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A. MURRAY, M. D.; CHAS. E. BLUMENTHAL, M. D.; E. C. SEGUIN, M. D.: | ALLEN MAYNARD, M. D., Cleveland, O.; Dr. C. WAN NIE, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES KELLY, Florence, O.; Dr. JOHN BECKER, Brighton, Iowa; Dr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes- barre, Pa.; JOHN J. CALD WILL, M. D., Brooklyn, and many other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an Electrical Instrument for medical purposes. CALL OR SEND FOR CIRCULAR AND PRICE LIST. FOSTER’s IE'_ALTTE NTT i Are furnished to Officers and Soldiers on Government account. I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMES A. FOSTEFr. 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cincinnmati, Ohio, or 172 Jef- ferson Avenue, Detroit, Mich. a ſº * * * SAML. P. THOMAS T.A.. I I, OR, N D E A LEF IN English, French and Scotch - GO. O. D's, 34 VVest Fourth Street, ("Z.W’("A.W.Wºź 7"/. IIRT S Made to order of N. Y. M. Muslin and 2300 HEAVY Linen, per dozen - - - $26 00 Wamsutta Muslin and 2100 HEAVY Lin- en, per dozen - - - - - - - - 33.00 Wamsutta Muslin and 1900 Linen, per doz. 30.00 Lonsdale Muslin and 1700 Linen, per doz. 27.0) First three qualities have ALL LIN EN Cuffs | and Neckbands. At above prices Cuffs are attached. Same quality of our own manufac- ture, ready-made, $3 per dozen less. Perfect satisfaction given or money cheerfully refunded. - Also import and Manufacture Men’s Furnish- ing Goods. t - Pike's opera-House, Fourth Street, Cincinnati; 931 Wabash Avenue, and 88 West Washington - Street, Chicago. CAMARGO MANUFACTURING COMPANY, MANUFACTURERS AND IMPORTERs of AND Window Shades, . 67 Wasz. Zºolºziz Szºnºr, CINCINNXT, 0. H. H. BRENEMAN, Proprietor, M. A. F. P. T. VVAIN'S - NIEVV E O O. Ex IS NOVV READY FOR CA NVASSERS. It contains over 600 pages of read ng matter, with 250 engravings, designed expressly for this work, by the best artists in the country. Agents now at work upon it. are meeting with unparalleled success. Agents at CircleVille, O., reports 25 orders in 2 days; one at Louisville, Ky., reports 175 orders in 8 days; one at Middletown, Conn., reports 200 orders in 12 days; one at Cincinnati, O., re. ports 250 in 12 days. Early applicants secure choice of territory. For circulars, terms, &c., address NETTLETON & CO., 161 Elm Street, Cincinnati, O. BASCOM & CARPENTER, Stationers, Printers Blank Book Manufacturers, 136 VINE s'TEREET, &\\\\\\\\\\\e E. D. ALBRO & BRO. IMPORTERS AND MANUFACTURERS OF FCREIGN and DONESTICwOCDS In Veneers, Boards and Plank, fºil-Millſ, (al-Bullier'ani air-Buitri'Wii, The only house in the Western country that saws Spanish and Mexi; can Cedar for cigar-Box Makers. We import our own wood direct, and can sell at prices to compete with any and everybody. Also º keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. Office and Warerooms, 136 and 138 West Second Street, Veneer Mill, 507, 509, 511, 513 & 515 W. Sixth St., CINCINNAT1. -º-º-º-º-º-º-º-º-º-º-- *-*-*-º-º-º-º-º-º-º-º-º-º-º-º-º-º-º-º- *-ºs - -------------- -*-*-*-*-*s-s-s-s- -----------as-ºs-mº-mºm- *** * *-*-*-*-*-*-*-*-*- •s------------------ee-m-s-ºs-ºs-wºmmºns -- a-------------------------- *#sº º ===sº i. tº º-t #Egº :-----|| : ----- i - - sº º t - ſ | || Nº.: list §:=#º: | GOOD SA The GOOD SAMARITAN HOSPITAL is pleasantly situated on an eminence It is handsomely furnished throughout, and is provided with all the necessary ap". Portičoes, with commanding views, surround the whole house, and wide of Sixth and Lock streets. pointments of a First-class Hospital. ;iſ ===#|| || || || º ill # I ſº E-tº # #!!! f i º | i S a. * * * **** * * §§§ºš% > -->==s: E- E-ºs-Sºº-ºº: SEEº-S gº iſſiſſiſſil | ſ : ºfflº º i ſº º º - E. -º-º-º-Hillſº > -ºll||{{ } it. iſſilij *; ||||||||||||||| lºſ # [[IIII # º | ºf: º # § # % | ! # wºº % & § § ºš Lº Sº sº 2 º # º:Sº §: # sº º Pº sºº a- º: ºº 2.- # ; §§ § º- º, £5 2. º% sº E. S. É 5. āş, §: # sº º : º -º:wº º §§ º 3. --> º ### Fº º *w- Zºº ſº 5: * § 2. 3. 5. - # º - --> # 5 º º š º ::::::: ºº::s: º 5.º. És?: * £2::$º º %. ºf, ºr, º º ſ: % ſº ..?% % #%% ########!/º =#. % ſºft ā- =º ºff. º *- #7%% º' Ž % % * ZZ, ºv/9 -- ES’.” %à - * 2 -*- -º- •º- É - º 2. *>N. sº: 4% ºf -º-º-> . - a Zºº.2 ºf 222 #sº * - ë:SE Šsº T-E- MARITAN HOSEITAL. overlooking the city, at the corner halls and abundant windows secure that full and free ventilation which is so essential to health and comfort. Service is furnished by the systERs of CHARITY, Under the Superintendence of the well-known SISTER ANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. - *, The regular Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each Professor presiding over his own especial department. of the city any physician of their choice. - The GOOD SAMARITAN HOSPITAL presents extra inducements to quiet asylum in any case of protracted illness, or some stay is necessary in after treatment. Patients may, however, select from the regular profession Invalids throughout the State as a safe and in cases, more particularly, requiring Surgical Operation, where Rooms vary in price, according to the character of appointments necessary and service required, ranging, iº general terms, gº" Address, : SISTEER ANTHONY, between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand of EHospital of the Good Samaritan, corner of sixth and Lock ste., cincinnati.onio. McGrew, wo. 27 west rowarm screer, PIKE's OPERA HOUSE BUILDING, importer and Dealer —” I N → ~~ Diamond and Gold J ewelry, Watches for Ladies and Gentlemen, Sterling Silver T ableware, Bronzes, Antique and Modern; Marble and Bronze Clocks, -- Marble Statuary, G E N E R A L L Y. & yº S. Sºx ñ. - º * -º-º: † ::::::$ºº B i º º Nº. º W S. º: - º cº & Cº . . Tº Y." - - Sº 'º fºº #: NºN º sº Z º A. º: % ; : 5.3.x: . rº. ſº i º j; ſºft º | .*. ºft|† .# | ; ºft| º lſº | º S., NZ ... ; | ; : = Fijū º|| ..}|† # ºši. º Ellº! CaSPAN: - ſ º . " 'i. I #: #ſ. CINCINN ATI. IET A C U L T Y. J AM ES G R A H. A. M., M. D., D E AN, IProfessor of the Theory and Practice Of Medicine and Clinical IMedicine. ROBERTS BARTHOLOW, M.D., Professor of Materia Medica and Therapeutics. W. H. GOBRECHT, M.D., Professor of Anatomy. P. S. CONNER, M.D., Professor of Surgical Anatomy. W. W. SEELY, M.D., Professor of Diseases of the Eye and Ear. SAMUEL NICKLES, M.D., Professor of Physics and Medical Chemistry J. A. VI. HX S TI. . W. W. DAWSON, M.D., Professor of Principles and Practice of Surgery and Clinical Surgery C. D. PALMER, M.D., Professor of Medical and Surgical Diseases of Women. T. A. REAMY, M.D., Professor of Obstetrics and Diseases of Children. JOHN L. CLEVELAND, M.D., Demonstrator of Anatomy. CHARLES KEARNS, M. D., Assistant to the Chair of Surgery. W H ITT A. Ex E F, , g Professor of IPhysiology and Secretary of the Faculty. ,--~~ T. LOU19 BRow N, Prosector of , natomy. Janitor, College Building, Sixth St., bet. Vine and Race. Printed and Published by Nohais & MURRY, Medical College of Ohio Building, Cincinnati, * wº- •. *** - 24 ~ : . . ….s º'º'; ' , , , , , , ; *… ". . . . - • A. ** - -3.3% s'. . . . - :**": *** ,” * “. TERMs—$2.00 ׺ PUBLISHED EveRY SATURDAY. per year, invariably in advance. All Communications relating to Publication must be addressed to the Editor; . . . . . all Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer. 3. Aºr == - - • - * --~~~~ • X , L- - ~ r- - F ºr T++E sºrtriotºrwºr's sur CINCIN IN ATI, M.A. R. C.H., 1872. IPI IETMLIEENT*r- —-w- _* * *- MEDICAL COLLEGE OF OHIO, sixTH & VINE stEEIs. . . SPRING COURSE of 1872. . . *- - - • *-* ~ * --~~3. Sº -, * → ~ * * DIRECTORY... . HOSPITALs. CINCINNATI, . . . Twelfth and Plum Sts. GooD SAMARITAN, ... is . . . Sixth and Lock Sts. .* * ... • +----. * * HoFELs. . . . . BURNIT ſous E, . . . ... N. E. Cor. Third and Vine. . GIBSON Hous E, “ . . Walnut, bet. Fourth and Fifth. WALNUT STREET Hòusī, - ***. . . . . Walnut, bet. Sixth and SPENCER HOUSE, . . . . - ? . - Broadway and Public Landing. GALT House, . . . . . . Cór. Main and Sixth. CRAwford Hous;. Cor. Sixth and BEV is Hous E, Court and HEYL House, - Cor. Sixth and Elm. IIENRIE Hous E, * - Third, bet. Main and Sycamore. St. JAMES Hotel, Fourth, bet. Main and Sycamore. MERCHANTS' HOTEL, - Fifth and Main Sts. INDIANA House, 163 West Fifth St. CENTRAI, Avenue Hotel, - Seventh. Walnut. -- Walnut Sts. Cor. Central Ave, and Longworth. º -- - AMUSEMENTs. PIKE's OPERA House, - Fourth, bet. Vine and Walnut. WooD's THEATER, - . Cor. Sixth and Vine Sts. NATIONAL THEATER, " *. Sycamore, bet. Third and Fourth. MozART HALL, . . . , - Cor. Vine and Longworth. Wisweil's ART GALLERY, No. 70 West Fourth St. *-4– *- BANKs. LAFAYETTE, . . Third, bet. Main and Walnut. FIRST NATIONAL, ‘. . . - Third and Walnut Sts. . . . . GILMoRE & DUNLAP, Fourth St., bét. Vine and Race. . , - ...” & -- ~ ..** * * .* RESTAURANTs. - —ºur- l _**-*- CHURCHES. * * - -º-º-º-º-º: { $ * f BUCKEYE DINING SAïooN, 218 Vine, near Sixth St. HARDING's DINING SALoon, 259 West Sixth St. | HUNT's DINING SALgoN, 172 & 174 Viñe St. MERCHANTs', $ 168 Race St. : ºf Bowmas's, .. 99 West Third St. ST. NiCHolAs, a Cor. Fourth and Race Sts. FARMERS AND MECHANICs, i . . . . 192 West Sixth St. * , , § - No. 49 Longworth St. $4.50 -- ... BoARDING HousEs. Room AND BOARD. 138 (t ºf 5.00 # 160. “. . . 4.50 & $5 161 “ 5.00. 110 West Sixth St., 5.00 i. 216 * : 5.00. : 145 Elm St., , ; 5.00 105 West Fifth St., 5.00 109 {{ 4.50 & $5 125 f : 5.00 127 “. 4.50 & $5 206 º 5.00 227 {{ 5.00 Cor. Sixth and Race, 5.00 No. 10 Perry St., , 6.00 397 West Sixth St. - FURNISHED Rooms. No. 67 Longworth St. 87 “ 107 “. 134 { { - 109 West Fifth St. 200 {{ 294 Sixth St. - 319 Vine St. ... • . 338 “ 99 John St. BOARDING. . 70 Laurel St. 51 110 110 37 Longworth St. Central Avenue Hotel. George St. - Sixth St. Longworth St. per week. {{ & 4 {{ 't & PARKs. EDEN, East End. |LINcoLN; Freeman and Clark. WASHINGTON, Twelfth and Race. TYLER DAVIDSON FountAIN, Fifth, between Vine and Walnut. t.*i- - - METHODIST, i Sixth St., bet. Vine and Race. Seventh and Smith Sts. Fifth, bet. Sycamore & Broadway. CHRISTIAN, e º Eighth, bet. Central Ave. & Plum. CONGREGATIONAL, Vine St., bet. Eighth and Ninth. PRESBYTERIAN, Broadway, bet. Fourth and Fifth. Fourth, bet. Walnut and Main. Fourth, bet. Vine and Race. EPISCOPAL, Seventh and Plum Sts. Fourth, bet. Walnut and Main. . Fourth, bet. Sycamore & Broadw'y. UNITARIAN, - 4 Mound and Sixth Sts. BAPTIST, Ninth, bet. Vine and Race. LUTHERAN (German), - - Elm, bet. Court and Ninth. Fifteenth and Liberty. UNIVERSALIST, Plum, bet. Fourth and Fifth. SWEDENBoRGIAN, Fourth and Smith. CATHOLIC, Cathedral, Plum and Eighth. SYNAGOGUES, Plum and Eighth Sts. Mound and Eighth Sts. FRIENDS, Eighth and Mound Sts. ExPREss of FICEs. ADAMS, * * No. 67 West Fourth St. AMERICAN, No. 118 West Fourth St. UNITED STATES, - No. 122 West Fourth St. HARNDEN, No. 67 West Fourth St. LIBRARIES. MEDICAL, Medical College of Ohio. PUBLIC (including Medical), Vine st bet. Sixth and Seventh. MERCANTILE, Walnut, bet. Fourth and Fifth. CATHolig INSTITUTE, Cor. Vine and Longworth Sts. THEOLOGICAL, t Cor. Vine and Sixth Sts. YoUNG MEN's CHRISTIAN Association READING ROOMs, Nos. 200 & 201 Vine St. THE STUDENT's suPPLEMENT. The Medical College of Ohio. When Cincinnati was a mere village and the Great West a wilderness—so long ago as 1818 —the Medical College of Ohio was founded by Dr. Daniel Drake. Even the present genera- tion of medical students need hardly be told that Dr. Drake was not only one of the most eminent citizens ever resident in Cincinnati, but also one of the most able and distinguished This ambitious and sagacious physician early dis- medical men this country has produced. covered the fortunate position of Cincinnati as a seat of medical education, and by perse- vering effort he secured the necessary legisla- tion and organized the Medical College of Ohio. The first Faculty meeting of the pro- fessors of the new college was held January 14th, 1820. The members present were Dr. Daniel Drake, President, and Dr. Elijah Slack, Registrar. Dr. named in the act of incorporation, Professor of Anatomy, and Dr. Coleman Rogers, Pro- Samuel Brown had been fessor of Surgery, but neither of these gentle- men were present. Great difficulty had been experienced in organizing a faculty which should not occasion disappointment; for Cincin- nati, then a frontier village, had not within its borders the profusion of medical talent which now exists in the metropolitan city. Owing to some differences which already had arisen in the new organization, Dr. Brown did not ac- cept his position of Professor of Anatomy and Dr. Coleman Rogers was dismissed by the President and Registrar at this first recorded meeting. The first commencement of the infant col- lege was held on the 4th of April, 1821, and seven candidates were admitted to the degree At this time the fac- ulty was constituted as follows: Daniel Drake, M. D., Prof. of Theory and Practice of Medicine. º Jesse Smith, M. D., Prof. of Anatomy and Physiology. * Benjamin S. Bohrer, M.D., Prof. of Materia Medica, Botany and Clinical Medicine. Elijah Slack, A. M., Prof. of Chemistry and Pharmacy. John D. Godman, M. D., Prof. of Surgery and Demonstrative Obstetrics. Two of them, Drs. Drake and Godman, had a national reputation which, indeed, has con- of Doctor of Medicine. tinued to our own time. The Cincinnati Hospital was formed also, by the personal efforts of Dr. Drake, and was, from its origin, the clinical department of the College. This was really the first combina- tion of clinical and didactic teaching in the United States, whatever claim may be set up in other quarters for the honor of priority in this important movement. In the minutes of a Faculty meeting held November 1st, 1821, we find the following rule: § 1x. Resolved, that the matriculated stu- defits shall be privileged to visit the Hospital with the Medical and Surgical attendants throughout the present year, and that it shall be the duty of said attendants to render the practice in that institution as instructive as possible. g This was a clear recognition of the value of true clinical, or bedside instruction. The difficulties which occurred in the first organization of the Faculty, continued during the first years of the struggling institution. The internal dissensions arose from the powers given by law to the Faculty, who regulated all the affails of the college, even filling the va- cancies in their own numbers. At a meeting held March 7th, 1822, Dr. Drake presiding, the following business, as appears by the min- utes, was transacted: “On motion of Dr. Smith, which was second- ed by Prof. Slack, it was voted memine contra dicente that Daniel Drake, M. D., be dismissed from the Medical College of Ohio.” Four days afterward this vote was canceled, and Dr. Drake restored, in orderit subsequent- ly appeared, to offer his resignation, which was accepted. Four times this able, ambitious and restless man entered the Faculty and quitted it, but at last he ended his eventful career in the institution which he had formed thirty-four years previously. Dr. Drake died on the 5th of November, 1852, just at the opening of the winter session. The Medical College of Ohio has heretofore been famous for the dissensions in its Faculty. The occupants of the Professorships have been men of positive qualities who had opinions of their own and did not hesitate to express them. Differences were common, and were expressed with energy, and fought with obstinacy. Not- withstanding these differences, lectures have been delivered for fifty years, and at least 1,900 graduates have gone forth with the di- ploma of the College. Eminent men have been connected with its Faculty, and men have risen to eminence who received their medical training within its walls. Drake, Cobb, More- head, Godman, Mussey, Gross, Lawson, Harri- son, Blackman and other distinguished physi- cians have been connected with the Faculty. Profs. Byford and Rea, of Chicago; Prince, of Jacksonville; Waterman, of Indianapolis; Murphy, Stevens, Taylor, Bramble, Thacker and others, of Cincinnati, are numbered a- mong its alumni. In the selection of profess- ors the College has not been unmindful of its own graduates, and in the present Faculty there are several who hold its diploma. As the Medical College of Ohio was for years the only Medical School in Cincinnati, its management was a fruitful source of dis- content in the profession of the city. The professorial positions were, of course, few in number, and the aspirants for professional The Trustees and Faculty, moved by a sense of what was most honors were numerous. necessary for the College, frequently selected eminent men from abroad to fill posts in the College. Thus, Godman, Gross, Mussey, Bläckman and others were, as the phrase goes, imported. It might have been presumed, in- deed, that the addition of eminent men to the professional ranks of our city would be highly considered; but it was far otherwise. Those who aspired to places received with open dis- trust, and even hostility, men who have con-T ferred honor on the profession of the city. Another bone of contention was the con- nection of the Commercial—now Cincinnati- Hospital with the College. For forty years the Faculty of the Ohio College were the ex- This ar- rangement—an arbitrary and exclusive, and, clusive attendants of the hospital. therefore, offensive one, it must be confessed— gave to the Ohio School an almost entire mo- nopoly of medical teaching in this city and prevented any successful rivalry. Professors in esse and posse, not connected with the of- ficial School of Medicine, were, therefore, bitterly opposed to this arrangement, and left no means untried to dissolve it. For forty years the contests over the hospital control raged with more or less violence, and have finally culminated in severing the connection of all college professors with this charity. Notwithstanding the frequent and bitter con- troversies which raged on these questions, a medical millenium has constantly been looked for by the profession of this city. A young medical college which was instituted to provide for “home talent” was organized out of these professional elements most hostile to the Ohio College. After a few years of precarious ex- istence, this institution, under arrangements termed the “coalition,” was swallowed up in the Ohio College. At the commencement held March 1st, 1858, the ad eundem degree of the Medical College of Ohio was conferred on all the graduates of the Miami College. The era of good feeling—the millenium—inaugurated by the union of the two Faculties did not long continue. We find that in 1860, these antago- nistic elements had burst asunder; the Miami professors were sent adrift and the old Ohio College professors united in a new organiza- tion. The semi-centennial exercises of last year closed fifty years of eventful history. The Medical College of Ohio entered on her 51st year stronger than ever, and with a brightened prospect of continued usefulness and renown. The results of the last session surpassed even the most sanguine expectations of success, and the SPRING Course of ’72 bids fair to excel to the same extent, all previous sessions of its kind. With a comparatively young, energetic and united Faculty to continue her 3areer— with a past renown to incite to higher aims, what shall prevent the future from becoming more glorious than the past has been eventful! * CLINIC, PUBLISHED EvKRY SATURDAY. T E R M S-$2.00 - *- a. Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editor: All Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer. —dº M A R C H 16, 1872. No. 11. or N C IN N ATI, JAS. T. whitTAKER, M. D. Editor. No. 101 West Ninth Street, Cincinnati. -A-SSOCIALTE EIDICTORS. W. W. D.Awson, M. D. THAD. A. REAMY, M. D. P. S. ConneR, M. D. . C. D. PALMER, M. D. W. W. SEELY, M. D. SAMUEL NICKLEs, M. D. CHAs. KEARNs, M. D. JNo. L. CLEVELAND, M. D. RoBERTs BARTHollow, M. D. - coars are ce. |Fashionable Hatters, IMPORTERS AND MANUFACTUBERS OF £ABEES' Rººs, 92 wrest FOURTH ST. - . . - - Opposite Post Office, CINCINNATI. saw-special Inducements to Medical Men- ºbesign:sº ENGRAVERSºWooDºº W. W. SEFLY, M. D., - - - - - - - TREASUREE. No. 118 west Seventh Street, Cincinnati. C LU B R AT ES. 4 Copies to one address. $ 7.00 6 “. . . “ 10,00 12 44 && 18,00 G O N T E W T S. - -* Page. oric INAL ARTICLES - Experiments in Epilepsy by Brown-Séquard, M. D., F. R. S............121|. Valedictory Address by Thad. A. Reamy, M. D 123 - TRANS LATION Cancroid, Impetigo, etc. Their Diagnosis and Therapy, by M. A. Duvergie, [From the Bulletin Therapeutique, Nov. 30, 1871]......126 scIENTIFIC NOTES spontaneous Hydrophobia—The Lacto-Phosphate of Lime in Fever ..127-129 * * * *. and Conval - NIE DIGALL NEWS. Lessons from Sandringham—Marriage and Crime--A Successor to the Zouave—Dogberry-cal—Honors to Dr. Gull....................129-130 - correspond ENCE Syphilis corpuscles (From Bost. Med. Journ., Mar. 7, '72.)— Anonymous—Not a Case of Conscience ...130-182 cLINICAL MEMORANDA ‘Digitalis an Antaphrodisiac. - 839 HOME NEWS 132 The spring Course of 1872. 132 THIS week's Clinic is of unusual interest in its original matter in the novel treatment of epilepsy suggested by its distinguished author. ... • - The translation on cancroid and allied diseases takes up to-day the therapy of these affections. will be concluded in the next number. The note on the lacto-phosphates in fever, etc., is of practical value. And then, we have a glance “at the other side” of the new discovery in syphilis. - The This subject ºsºl & 2 WEST FOURTH Sºº-ºº: i. Bºzº SºGINCINNATIOHIo: *~ww- J. TAFT, w. TAFT. J. & W. TAFT, TENTTIsTs 17 WEST FOURTH STREET, CINCINNATI, O. A Monthly Journal, CONTAINING 48 PAGES, Devoted to the Interests of the Dental Profession, *. - * * * COID T.I.VIEER, OIT, O I DO ER, IL, IE S S A. IN ID IPA. I. A. T.A.. I E I L I E • In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERs & BARTLETT, of Portsmouth, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. - Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachitic Affections, in Chronic Rheumatism, &c. The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more-extensively its merits are tested by the medical profession the more highly will they be appreciated. * g The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. *— William Autenrieth, No. 71 west sixth sºrrºr, BETWEEN WAINUT Añº VINE, cincinnati, ohio, MANUFACTURER OF AND DEALER IN III III IIHRIII III, Abdominal Supporters, Trusses, CLUB-F00T SHOES, SPINAL APPARATUS, ETC Keeps constantly on hand a full variety of Metalic and ERubber Syringes, Stomach. Pumps, IEtc., stockings For vamloose veins. Special attention given to the fitting of Apparatus for Deformities. ~gº Agent-for DR. L. A. BABCOCK'S Silver Uterine Supporter, -ALSO– DR. AHL'S POROUS FELT SPLINTS, - - -AISO- - T) A. Y. * S S E LIN TS ROBERT CLARKE & Co's. LIST OF NEW MHL iBTH in MBIII; inſ; |GREEN’s PATHOLOGY AND MORBID ANATOMY, 8vo. Cloth. $2 5o DUCHENNE'S LOCALIZED ELECTRIZATION. 8vo. $3 oo DILLENBERGER ON WOMEN AND CHILDREN’S DIS- EASES. 12mo. $1 75 BENNETT ON PULMONORY CONSUMPTION. 8vo. $1 5o FIRST HELP IN ACCIDENTS. 12nºo. $1 50 BEASLEY'S DRUGGIST RECEIPT BOOK. 8vo. $3 50 ECHEVERRIA ON EPILEPSY. 8vo. Cloth. '$5 oc HOWE ON EMERGENCIES. 8vo. $3 oo - HAMMOND ON NERVOUS DISEASES. 8vo. $; oo RINDFLEISCH'S PATHOLOGICAL HISTOLOGY. $6 oo WARINGS’ PRACTICAL THERAPEUTICS, 2nd Am. Ed. 8vo. Cloth. $5 od Leather. $6 oo SCUDDER'S SPECIFIC MEDICATION. 12mo. Cloth. TANNER'S HANDBOOK OF OBSTETRICS. 12mo. WAN BUREN ON DISEASES OF THE RECTUM. Cloth. $1 5o * FLINT’S EXAMINATION OF URINE. 12mo. Cloth. $ 1 oo VOGEL ON DISEASES OF CHILDREN. 8vo. Cloth. $4 5o BEARD AND ROCKWELL’S MEDICAL AND SURGICAL ECECTRICITY. 8vo. Cloth. $4 50 ATTFIELD'S MEDICAL CHEMISTRY. Izmo. Cloth. $2.75 Leather. $3 25 *. BARTHOLOW’S HYPODERMIC MEDICATION. Cloth. $1 5o -- TURNBULL’S DISEASES OF THE EAR. 8vo. Cloth. $5 od TILT'S CHANGE OF LIFE. 8vo. Cloth. $5 od NEUMANN'S HAND-BOOK OF SKIN DISEASES. Cloth. $4 oo ANSTIE ON NEURALGIA. 8vo. Cloth. $3 oo. PANCOAST'S OPERATIVE SURGERY. 4to., with many plates. $1 o oo gº - HOOD ON BONE SETTING. 12mo. $1 5o RINGER'S HAND-BOOK OF THERAPEUTICS. 8vo. $4 oo $2 5o $2 oo I 2 II, O. I 2, III C), 8vo. hoºks PARTURITION WITHOUT PAIN. 16mo. I OO PROCTER'S LIGHT SCIENCE FOR LEISURE HOURS. 12mo. . $1 75 BERNARD’S PHYSIOLOGY OF THE HEART. 50 cts. BARNES’ OBSTETRICAL OPERATIONS. 8vo. $4 5o NICHOL’s FIRESIDE SCIENCE. 12mo. $1 50. WOHLER'S MINERAL ANALYSIS. 12mo. Cloth. $3 oo PLATTNER'S MANUAL OF ANALYSIS WITH THE BLOWPIPE: 8vo. Cloth. $7 50 JEFFRIES ON THE EYE. 8vo. Cloth. $1 oo MANSFIELD, A THEORY OF SALTS. 8vo. Cloth. $4 oo JEFFRIES ON THE SKIN. 8vo. Cloth. $1 oo GARDENING FOR PROFIT. 12mo. Cloth. $1 50 PRACTICAL FLORICULTURE. 12mo. Cloth. $1 5o FULLER'S SMALL FRUIT CULTURE. Izmo. Cloth. $1 WOODWARD'S COUNTRY HOMES. 12mo. Cloth. $1 5o DARWIN'S ORIGIN OF SPECIES. 12 mo. Cloth. $2 oo ARTHUR'S TREATMENT AND PREVENTION OF DE- CAY OF THE TEETH. 12mo. $1 5o TYND ALL ON LIGHT AND ELECTRICITY. THE AMATEUR MICROSCOPIST. Small 4to. BOOKS IN PREPARATION. BRYANT'S PRACTICE OF SURGERY. BARNES ON DISEASES OF WOMEN. ROBERTS ON RENAL DISEASES. GUERSANT, SURGICAL DISEASES OF WOMEN AND CHILDREN. Medical, Scientific, and other Catologues sent on application. Any book in the above list sent by mail or express, free of charge on receipt of price- 5o I 2. In O. $1 25 $1 75 s: w. miliott's saddle-bass 65 West 4th Street, Cincinnati, Ohio. List of Pharmaceutical Preparations, MAN &JFACT iſ RED EY JøA.W WºZAZ & ZººZººZºº, PHºrrº.4 ºr F.H.I.A. —º- ELIX. PHOS, IRON, QUININE AND STRYCHNIA, ELIXIR OF GENTIAN FERRATED, ELIXIR, WALERIANATE OF AMMONIA, - (Goddard?’s Formula,) ELIXIR VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF. IRON, Hron, with Phosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Iron, Peruvian Bark and Choice Aromatics, * * ELIXIR OF CALISAYA BARK, - ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER WINE OF IRON, Citrate of Hron, and Pergaviaen Bark, FERRATED CORDIAL ELIXIR, - ELIXIR CALISAYA BARK, WINE AND BISMUTH, ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, º FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, - * TASTELESS COD LIVER 9ſº at TASTELESS COD LIVER OIL. FERRATED, *ē, BEEF, IRON AND WINE, Extraet of Beef, Citrate of Iron and sherry wine, ELIXIR WALERIANATE OF STRYCHNIA, WINE OF PEPSIN. - SYRUP SUPERPHOSPHATE OF IRON. 9 ELIXIR OF BISMUTH, COMP. FLUIDEXT. BUCHU AND PAREIRA BRAVA. st JIEPE*Os][TOR.I.Es. Bectum, Waginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great eare, and of every variety of combination. Lists sent on application. . - SPONGE TENTS.—For the Urethra, of every size and Btyle made of finest quality of sponge. * * * * * * * * , sº EFFEºle= } JAMES FOSTER, JR., & Co. Instrument Makers and Practical Opticians, Beg leave to return thanks for the patronage extended to them through a long series of years (having been established since 1836), and in the reorganization of their firm will endeavor to merit a continuation of the same. We wish it understood by the Profession and the Public generally that our invariable rule is, to make or import none but the best in- struments. Those in want of any of the acknowledged good aids of vision to imperfect eyes, will always find the best and largest stock of Lenses, Spectacles, and the best models procurable, with pains- taking skill to adjust them to all conditions of sight, at our house. Special attention paid to orders for Fine Microscopic Objects and Microscopic Apparatus, Magnifiers and Readers in great variety. edical Batteries, Barometers, Thermo- meters, Hygrometers, Urinometers and Rain Gauges, of the most approved constraction always on hand. All orders promptly and accurately filled. - JAS. FOSTER, JR. e F. S. SHACKLEFORD, } *ing * JAs. FosTER, JR. & Co. S. W. Cor. Fifth & Race Sts., Cincinnati, 0. TER. S.IN.INMA ER.S.H.’s - º:3°SS * *E= *. - - No. 758 BROADWAY, NEw Yob R HAVE been in the habit of applying and recommending the Truss I manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined. WIS A. SAY RE, M. D. - - Surgeon, Bellevue Hospital. From Prof. Willard Parker to S. D. Townsend, M. D., Surgeon to the Massachusetts General Hospital, BEG leave to state for the benefit of all concerned, that I have known Jº Dr. S. N. Marsh the last fifteen years. Mºr am in the constant. fiabit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a JRadical Cure of Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with any of the risks to , the patient that exist in many of the plans suggested and attempted to be cºrried into execution. I have confidence in Dr. Marsh as a gentleman of honor and integrity, and as such recommend him to the members of the medi- cal profession generally. WILLARD PARKER, M. D. : - Professor of Surgery, New York City Dr. S. N. Marsh's Patent Radical Cure, Truss, and all other kinds of Trusses, Shoulder Braces, Supporters, Elastic Stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical deformities, made and accurately fitted at the Radical Cure Truss offices of S. N. MARSH & CO., No. 2 Wesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. oppositE THE HIGH STEEPLE. F. E. SUIRz. E. S. WAYNE TT. THX. Suire & Co., WHOLESALE DRUGGDSTS, M. A.IN U FA CTU. R.I.N. G. £Hemists AND PHARMAceutists, CINCINNATI, OHIO. Have constantly on hand a full assortment of S)6),) EC4)(*)6]O pagos ANYo WXYeoxc)(N)es, C}{}(XSYYX)(CAX, Aeeaaarus, TESTS, MEDICAI, grass WARE, &c., &c., And solicits the patronage of the trade and profession. We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, alºne in accordance with the U. S. P. and other recognized authori- risk ANID R.A.ER. HX CHEMICALs. Of the popular class of preparations known as II, T, TIXIII-R, S, We manufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. Bitter Wine of Iron, An excellent Chalybeate and tonic, Wine of Iron, &c. AGENTS FOR BULLOCK & CRENSHAW'S sugar-coated Pills and Granules. Price Lists of preparations and of Sugar-coated Pills sent by Mail upon application. The long standing and well and widely known repu- tation of our house we offer as a guarantee for the reliability of our preparation, and the quality of the goods sold by us generally. Divided MEDICINES, *— The Divided Medicine Com’y, CINCINNATI, OHIO. ‘º The Company have the honor of bringing to the notice of the Profession, this NEW AND ExCEEDINGLY PRACTICAL METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. . . . . . The Divided Medicines are prepared by FREDERICK KRAUs, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MORE. - * 4. The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every Square will consequently contain accurately measured quantities. But not only SoluBLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINES. . . . . . This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, ; : *, *, *, and even idoo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. ', . . . . . . . . . . . Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE TO SPOIL BY ANY LENGTH of TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste... . . . . . . . . . - - Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calls with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own preseriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. - - - For Samples, Price Lists, and Agencies, address º - Box 2ese, Or FRFDERICK KRAUS, Chemist and Druggist, . Walnut Hills, Cincinnati, O. MR. FREDERICK KRAUs: . . . - CINGINNAT1, February 15, 1871. Dear Sir—The specimens of your “ Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: * , * + ... - - . . . SU LP II: MOſ. PPſ II....................... % grain in each square. ARSEN:AgID..........................I-20 grain in each square. “ GH IN IN I.......................] & 4 § { $6. CALOMEL... - 34 “ * : ; ; * * * 4 6 COPPER, ...“...............}% -- - $ & * - - - - ~ * r Respectfully You Bs, • J & • . E. S. WAYNE, Analytic Chemist. /* T IEEE THE C T , T TNT I C - 121 Vol. 2.] S A T U R D A Y, M A R C H 16, 1872. [No. 11. O R. I G IN A L A R T I C L E S. —se-e-a-— Ex P ER IM ENT's R N E PHL EP sy. BY PROF. C. E. BROWN SEQUARD, M.D., F. R. S. Professor of Comparative and Experimental Pathology, (Paris). A Lecture delivered before thé Cincinnati Academy of Medicine March 9th, 1872. Among the researches of the past twenty years no in vestigations are of greater importance and significance than those concerning the phenomena of arrest of ner. vous activity, the suspension, in other words, of the nerve force generated in the cells of gray matter in the brain and spinal cord. This phenomenon of arrest I may perhaps best illustrate by that sudden cessation of the heart's action which ensues upon a blow upon the epigastrium. The shock is thence conveyed to the brain whence it is reflected by the par vagum to the heart. This arrest or suspension of activity of nerve force thus engendered by peripheric irritation is full of promise in explanation of the action of remedial agents in the cure of disease. As you are all aware I have some time ago discovered the possibility of inducing epileptic convulsions in animals by injuring certain parts of the spinal cord. In animals thus rendered epileptic the least irritation, as that of tickling, of certain parts of the neck or face invariably brings on an epileptic attack. This irritation is of course transmitted through the sensitive nerves to the cells of gray matter whence it is reflected to the muscles through the motor nerves. Knowing, now, the effects of carbonic acid gas in in ducing collapse when brought to bear upon the larynx, I was led to believe that such an arrest of activity might be brought about by this agent as would interrupt a convulsive seizure. I found then by experiment upon these animals (guinea pigs) that when carbonic acid gas was directed into the larynx, in quantity just sufficient to permit recovery, that the fit would be in- Variably interrupted in form from one second to one second and a half. This interruption of the fit, more- over, was permanent, and was followed by that tickling of the nostrils with the forepaws which is always indica- tive of the permanent cessation of the convulsion. This result was verified in a great number of recently per- formed experiments during my last sojourn in Paris. It is essential, however, to secure this result, that the gas be somewhat forcibly injected, as it is necessary that the mechanical effects of a jet as well as its direct influ- ence upon the nerves be also secured. I found, more- over, that this immediate, or nearly so, cessation of the fit followed when the gas was made to traverse the trachea from below upwards by means of an opening in the tracheal tube. I now directed my attention towards the relief of an attack of epilepsy in man. For this purpose I visited the hospital for epileptics and paralytics in Paris where I soon had the opportunity of performing my experi- ments. - My first patient was a female in whom the epilepsy was complicated by a marked hysterical element, con- stituting what is known as the hystero-epileptic spasm. She had both tonic and clonic convulsions, bit her tongue, etc., yet it was plain to see that there was a decided hysterical element, as I have remarked, compli- cating the attack. In this case my remedy had no per- ceptible influence. I was more fortunate in my second case. In this patient the attack lasted usually 15-20 minutes. The convulsions were confined principally to one side. There was marked spasm of the muscles of the neck and chest. At first vomiting was produced which assumed a threatening aspect as I feared that strangulation might ensue as has indeed occurred in some cases reported. This fear however proved groundless. Over this attack my remedy had the happiest effect. The spasm of the muscles of the chest and neck relaxed in two minutes, becoming perfectly soft and flabby; a stiffness of the extremities lasted some eight minutes. The difference in the duration in this attack from previous ones, how- ever, proved conclusively the value of carbonic acid in abbreviating the duration and diminishing the violence of the seizure. Unfortunately my short stay in Paris after this experiment gave no other opportunity of confirming this discovery in man. Again: you are aware that one attack of epilepsy implies or begets such a condition of the nerve centres as will be followed by a series of attacks. This I have generally combatted with chloroform. When chloroform is promptly admin- istered upon the first attack before organic lesions are engendered the sequence of attack is interrupted. I have also met with the same results in the use of car- bonic acid. In three of the seven animals in which I provoked the epilepsy there has been a stoppage of the series of attacks after one had been treated in the method described. Moreover, I have observed that a certain number of the animals have been apparently cured by five or six applications of this agent, that is, epilepsy could no longer be induced artificially. To be sure we often have spontaneous cures of this disease in the guinea pig, but these never ensue in less than 6-8 weeks time and I have observed in these cases the following singular phenomena: when this animal is recovering from epilepsy the hair on those parts of the face and neck, 122 T H. H. [MAR. 16, 1872. C T , ITN. T.C. which when irritated excite an attack, gradually fall off and the animal is only cured of the disease when the spots referred to have become perfectly denuded of hair. The point that I desire to bring into prominent notice is the fact that peripheral irritation lowers, or tempo- rarily suspends the activity of the gray cells of the base of the brain and the spinal cord, and it is in this way that all such remedial agencies act. There are some cases, for instance, induced by laryngismus. Now in these cases it is well known that cauterisation of the larynx has been resorted to with the best effects. In a case of this kind under my care I adopted this expedient, cauterising with nitrate of silver just before the attack, with the effect of prevent- ing the paroxysm. In this case the paroxysm had recurred every 49 days. This periodicity of recurrence would seem strange were we not at all So familiar with the peculiar oddities of this strange disease as not to be astonished at any of its freaks. He had one attack in- duced by allowing himself to become exasperated with a servant at table after a full meal but, with this excep- tion, he was free from epilepsy for three years afterwards when he died from a fall, it may have been in an attack, but as he was of intemperate habits it is possible that it was during intoxication. In what I term, now, spinal epilepsy where there is congestion in a limited portion of the dorsal division of the cord, the phenomena of arrest may be induced by the lightest peripheral irritation. This is exemplified in a case I had under care by the discovery, not my own, an accidental one of a negro Servant, that a vigor- ous pull upon the big toe averted the threatened attack. This was effected of course by the transmission of the peripheral irritation to the cells of gray matter where an arrest or suspension of activity was brought about. You may perhaps have heard of the fact that in Corsica and some other countries they are in the habit of treating and curing sciatica by burning the ear; this is only another application of the same principle. I had in my hands once the case of a young girl, a clergyman's daughter, a patient with very severe epilepsy in whom the convulsions were more marked on the left side of the body which is, indeed, the rule. Here there was a distinct aura epileptica. I directed the nurse to try the effect of pinching the body, first the arm of the left side then the leg, afterwards both members of the opposite side and then various parts of the body. These manipulations were attended with good results; in some cases the attack was undoubtedly prevented. And so in compressing a limb or in binding it with a ligature —proceedures Sanctioned by long practice—we only irritate certain nerves and this irritation is transmitted to the cells of gray matter at the base of the brain and in the spinal cord. We used to think that in adopting these means we prevented something from passiug from the periphery to the brain; now we know that we act from the other direction, we prevent something from passing from the centre to the periphery. I had the opportunity while last in Paris of trying the effects of carbonic acid gas in the convulsions of strych- nia poisoning. Having induced the toxic effects of the drug in Some animals, I proceeded to inject the gas into the trachea and bronchi. The experiment succeeded in arresting the convulsions in a very short time. By this means it is hoped that the fatal effects of the poison may be held in check, in man, until evacuants and an- tidotal remedies may be administered So also in convulsions from loss of blood, the same cessation was brought about by the intralaryngeal in- sufflation of carbonic acid gas. I tried this experiment in three instances, two pigeons and one duck. It was a matter of regret to the speaker that he had not brought his animals with him. He did not expect to lecture on this occasion but upon some subsequent opportunity, and such would perhaps repeatedly occur, he would take pleasure in demonstrating these investi- gations. While it was a matter of indifference as to whom should be credited with these discoveries, it was nevertheless a great pleasure to the speaker to be able to present them first to an American audience and more especially to one in Cincinnati. [We recall for the benefit of our readers, a few of the important contributions made to science, by the distin- guished physiologist Prof. C. E. Brown-Sequard, now honoring our city with a visit. Both the physiology and pathology of the nervous system have been enriched by his discoveries. He first demonstrated that the sensory fibres of the spinal cord decussated at all points. By section of the lateral half of the cord he showed that anaesthesia followed in the parts below on the same side, and hyperaesthesia on the opposite side. The writer of this note was fortunate enough to have seen Dr. Brown- Sequard perform these vivisections and can testify to his marvellous dexterity. He enlarged the field of vaSO-motor physiology after Bernard's great discovery of the effects produced by division of the cervical sympathetic, by demonstrating that contraction of the vessels ensued on galvanisation of the divided extremity of the nerve. He is the author of the modern doctrine of reflex paralysis. -- -, * He has shown that irritation of the skin over the kidneys causes contraction of the vessels of these organs, and that immersion of one extremity in cold water will cause a fall of temperature in the other. He was the first to demonstrate the power of ergot to diminish the blood supply to the spinal cord. He has lately been engaged in Some very curious re- searches on the pathology of epilepsy; and has shown on guinea pigs that section of the Sciatic, and of certain parts of the spinal cord will be followed by gonvulsions when certain “zones” are irritated. * The lecture above given is on some points developed in his recent investigations]. MAR. 16, 1872.] T H H C T, ITNT c. 123 A D HD R E S S Waledictory to the CIass of the Fifty-First Annual Session of the Medical College of Ghio. BY PROF. THAD. A. REAMY. GENTLEMEN: I address you by appointment of my colleagues. At no period in the history of the Medical College of Ohio could it have been other than an honor to receive such an appointment. This conclusion is legitimate whether we consider the distinguished men who have composed its faculties or the alumni who, during its fifty years of continued success, have gone forth bear- ing its honors. - One year ago, on an occasion like this, an able and elaborate historical account of the rise and progress of this institution was given by one of her former most distinguished teachers—also a member of her Board of Trustees.i. One session more has been added to her fifty; one year more to her growth and strength. One class more has assembled within her time-honored precincts—and from that class, having passed successfully a rigid writ- ten examination, stands before me to-night one of the largest and most intelligent graduating classes which she has ever sent out honored with her parchments. The latter statement, gentlemen, is due to your in- dustry, to the distinguished competency of my col- leagues, their faithful and indefatigable labors in your behalf during the session just closed; and to the fine advantages which Cincinnati offers for medical educa- tion. Last, but not least, to the increased facilities which this college posesses over other schools. A few words as to the truth of this last remark. The proposition needs only to be stated, not argued, to obtain the assent of all well-informed minds that the school, which, other things equal, can afford most clinical in- struction of the most practical and varied character to its pupils, has at once established its claim to superiority of advantages. How is this with the Medical College of Ohio gentle- men 2 First, you have had access, on equal footing, with the pupils of other schools to the wards and amphi- theatre of that great charity, justly the pride of our city, the Cincinnati Hospital: an institution which in architectural grandeur and beauty, in all its appoint- ments, and in its noble mission is at once an honor to our people, and to Christian civilization. You have heard the clinical lectures, and witnessed the operations of the gentlemen composing the staff of that charity. So far, you are but equal with others, but; Secondly. you have had access to the wards and amphitheatre of f Prof. M. B. Wright. another, no less noble private charity—the Good Samar- itan Hospital, under the management of Sister Anthony, aided by her corps of untiring nurses—women who de- vote their lives to the welfare of others. This institu- tion in proportion to its capacity, is unsurpassed in its good work, its mission of mercy to the afflicted. More- over, as to facilities for clinical teaching, it is now en- dowed with scientific apparatus, electrical, etc., unsur- passed in completeness by any on this continent. Further, its staff is composed largely of the faculty of the Medical College of Ohio. To the benches of this hospital you, gentlemen, as matriculants of this college, have eacclusive access. Again; during the past session clinical lectures have been delivered daily in the Dispensary of the college, where the material has been not only ample, but the diseases discussed and treated, have covered the widest range. The value of this course can scarcely be esti- mated, for in it you were permitted to auscultate, percuss and often prescribe for the patient yourselves—advan- tages which are. enjoyed in no hospital in the land. Your appreciation of this means of instruction, was rec- ognised by your teachers, as they found it difficult sometimes to induce you to leave the dispensary room when the hour had arrived for the hospital lectures. When our dispensary material was abundant, it was often quite difficult to dispose of it before the hour. And I may add here, by way of parenthesis, that it is to be hoped in the future such mutual arrangements can be made between our college and the hospital, as not to have clinical lectures in each at the same time, for while it has been and will continue to be our duty and policy tosurge all our students to take the hospital tickets and attend the lectures and operations; still, our dispensary clinical advantages have grown to such magnitude, and are on such firm footing that we cannot for a moment think of surrendering them. Such a course would be an abandonment of one of our most distinctive claims of superiority. & A spring course, suplemental to the winter session has been already announced, and what has heretofore been unusual East or West, will be conducted by the regular members of the faculty. This course is to be eminently practical and operative. Moreover import- ant additions are to be made to our cabinet, chemical apparatus and other means for Scientific instruction. But I must desist from this line of remark as I have no time to pursue it. So much was considered proper to be said in justification of my claim as to our advantages for teaching, and so much was due to you, gentlemen, as now our alumni; and to you our honorable board of trustees, as an assurance that this institution which, under your fostering care has become historic, is still pushing forward with renewed energy and vigor, deter- mined from year to year, not only to elevate the standard of medical education, but to bear it herself in the first ranks of progress. But, gentlemen, why have you en- tered upon the study of medicine? Why subjected 124 [MAR. 16, 1872. TIE-L E C T.I. N. T. C. yourselves to a rigid course of mental discipline in pur- suit of this special branch of human knowledge? True, medicine has been acknowledged one of the learned pro- fessions, but have you therefore been lured to seek it 2 can you endure the Herculean labor demanded of those who win access to her inner courts and higher walks? It is true, if you succeed in obtaining practice it will yield you a competent support; but is not almost any other field more promising in this regard? To-night you go forth from us; our relations as teachers and pu- pils close. You have been trained in the science of medicine and just now commissioned to enter upon its practice. Ere you go I would have you remember this profession is not, mnst not, be mercenary. The precious stones to be wrought into its temple must not be handled by unskilled or defiled hands. Have you realized that the mission of the physician is to relieve human pain? A boon inestimable; to preserve that gift of the creator which includes all other gifts—life? “All that a man hath will he give for his life” is a wonderful truth, though first formally announced by a character not above suspicion. God has implanted a love of life in the human breast commensurate with its far reach- ing consequences. So far as we know either from rea- son or revelation in it is man's only opportunity of working out the objects of his creation, of preparing for eternity. Again, what are the ties of kindred ? Deeply as they are implanted in the soul, life severed, and they are de- stroyed. That committed to your keeping therefore, is a sacred trust. Are you qualified in heart and head to take it? If so, go forward to your posts of duty. If not, I beg you abandon this and seek other avocations. But, can human life be preserved ? Can disease be neu-, tralized 2 Pain subdued 7 These questions press them- selves upon you as you stand at the threshold of a pro- fessSon of whose votaries so much is required—and the voice of inquiry becomes louder and more imperative in view of the skepticism which so much obtains in the public mind on the subject, a skepticism, I grant, largely due to ignorance, nevertheless to be met and all the harder to meet because of the ignorance. Gentlemen, I would have you enter the profession at whose door you stand to-night with confidence in its resources and pow- ers. The sickly cry of those who are in it against the power of therapeutic agents over discase; a cry whose language is “I have lost confidence in medicines” is gen- erally irrefragable evidence of ignorance, and therefore those who utter it should go out. I can in the brief time alloted but name a few of the answers which should give assurance. Most of them modern in discovery and application. But first note the absolute power of sulphate of quinia not only to neutralize the force of malarial poison in the system generally, but to wrest the victim of pernicious inter- mittent from the very grasp of death and hand him over to health. The power of iron and bitter tonics to transform the pale, nervous, anaemic girl, who is about to become the victim of some inhaling quack because she has cough, to all the health, vigor and beauty of young womanhood. The power of iodide of potassium to disperse gummat- ous tumors of the brain, heretofore in all cases incurable. The power of bromide of potassium in the acute stages of cerebral congestion to lessen the diameter of the ves- sels, to remove pressure and thereby not only allay pain, but in many instances, avert effusion and its serious consequences, procuring tranquil and refreshing sléep in cases where delirium and convulsions were im- pending. In this connection I may say, that through the door which recent histological research has opened showing the influence of the vaso-motor nerves over cerebral congestion and anaemia, a light is pouring which is destined to illumine that mysterious disease epilepsy, and others of kindred character, less formidable, but heretofore equally inexplicable; moreover, there is to be richer fruit than simply this knowledge affords; experi- mental demonstration that there are certain drugs which will so act upon these nerves as to dilate or constringe the blood vessels to which they are supplied constitutes at once an achievement in scientific therapeutics which must mark the age in which it was made. * * * Again, here is a patient suffering from paralysis, from progressive muscular atrophy caused by disease at the nerve roots. The intelligent practitioner employs elec- tricity, the nerves are restored, and the muscles again are creatures of life. That which in another age was the subject of a miracle has become the legitimate work of the physician. In the same community is another paralytic, same members involved. The modern im- proved tests of diagnosis are applied—the cause is dis- covered to be hemorrhagic effusion within the cranium. Will you apply electricity here, as in the former case? No, that which cured the former will certainly make this case worse by increasing the cerebral congestion. But administer bromide and further along iodide of potassium, gradually the cause is removed and the pa- tient recovers. These cases are typical and prove the power of our art over disease. But the sword is two- edged. Here is proof–on the one hand that the bat- tery so potent for good in the hands of the educated medical man, may, nay often does become an engine of death in the hands of the ignorant. Again, these two cases which are not hypothetical, but real, at once burst that dogmatic bubble, similia similibus curantur, which treats symptoms alone. * + k 3& Fibroid tumors, heretofore irremediable in regions inaccessible with safety to the surgeons knife, are now resolved by electrolysis. Hydatids of the liver often disappear under similar treatment. Aneurismal tumors are dissipated under the power of the same agent which Franklin coyed from the clouds with his kite. * * * Here is a man with an old and indolent ulcer which has resisted treatment for twenty years. The surgeon. snips a piece of healthy skin from a neighboring part and plants it in the midst of the diseased mass, with MAR. 16, 1872.] TIH. H. cI, IISTI c. 125 what result? A perfect cure. The same process will prevent those frightful cicatrices which so often deform the features after severe burns. Ovarian tumors were in former times a great source of mortality, and such was the fearful mortality attendant upon their surgical interference less than thirty years ago, that a most dis- tinguished physician pronounced any man who would attempt such interference a murderer. Now, however, under improved surgical management the recoveries are 70 per cent. It is but little more than fifty years since Laennec announced to the profession his discoveries in physical diagnosis. Now the experienced auscultator distinguishes the different forms of pulmonary consump- tion, and separates the curable from the incurable. He detects also incipient heart lesions, defines their ex- act character, and gives such treatment as will ward off fatal results. Precision in these cases is the diagnostic law. * # * - Liebreich’s discovery of crotonchloral, an agent which produces anaesthesea of the entire body without sus- pending consciousness, promises magnificent results. The few therapeutic facts, gentlemen, to which your at- tention has been called may suffice for my purpose. The entire evening could be occupied in the citation of others equally positive. But these answer the inquiries with which we started out. I cannot close without call- ing your attention to the crowning scientific triumph of the age which comes to us from Vienna, authenticated by such names as Skoda, Hebra and Stricker. I refer to the discovery of Dr. Lostorfer of the characteristic cor- puscle of that specific malady which has been the curse of civilization, and which we suspect as tainting and underlying many intractable forms of disease whose origin could not heretofore be clearly made out. For more than half a century trained eyes have in all parts of the world been peering down into minute structures for these corpuscles. It remained for Dr. Lostofer with a Hartnack microscope, No. 3 eye piece and a No. 10 immersion lens to see them. This discovery will exert an influence upon positive diagnosis, and thereby direct therapeutics to results which cannot now be even esti mated. Already it in part verifies and at once simpli- fies the germ theory of disease. As already intimated’ most of the facts cited are of recent demonstration. Think not therefore that they are the fruits of this gen- eration. No ; they are the discoveries of the aggregate experience and wisdom and work of medical men in all countries for forty centuries. * * * Under the in- fluence of this science human life is annually lengthen- ing. It has been my purpose to-night to speak only of things which should encourage—give you faith, hope and zeal. There are many uncertainties and imperfec- tions in our science and our art, of these you have been well apprised during the course of instruction just closed. - I speak now of triumphs not failures. We hear occasionally from our legal brethren, politicians and statesmen, and also from our theological teachers, that medical men disagree, teach different systems, and therefore the science must be unreliable. Let us take no time to argue with these gentlemen, for who does not know that the laws of every country differ, accord- ing to the educated conscience of their makers. And that lawyers seldom agree as to the construction of the same law. Do statesmen even of the same political party agree as to high-tariff and free trade? Even now is not the parliament and cabinet of the two greatest nations on the earth, disputing as to the gramatical construction of a treaty ? And, of our theological brethren we would inquire, have there not been 180 creeds since Constan- tine 7 No truth is invalidated because men differ as to its construction. Christ the saviour of sinners, and faith in Him is the grand truth of Christianity—creeds do not invalidate it. Neither can differences of opinion among medical men destroy the truth of medical science. The profession upon which you have entered challenges your best powers, your loftiest ambition for usefulness, for greatness. And now let me say the difference in men as to what they accomplish, is not a difference in genius—success is not due to friends or fortuitous circumstances. Shall I give you the formula for success. The foundation is faith, the superstructure is work. I knew of a man who concluded to plant an orchard—he transplanted from a native thicket, young crab Scions. The soil was good—the trees grew. He was a devout man and I imagine as he stood under his trees, as he was wont, and looked up through their branches he prayed, “O Lord give us this year nice pippins, but his teeth were edged with sour crabapples; notwithstanding his devotion—to get the pippins he must graft and bud. Gentlemen, if you wish the richest fruits of professionel success, you must graft and bud. What more shall I say? In all your professional relations with your patients, to those who place their own lives or the lives and health of their friends in your hands under God, indeed in your relations to all mankind, be itrue to truth and honor, in heart and Soul, be pure. Finally as a faculty we bid you God speed and an affectionate farewell. - — —s-e-a---— — THE ANIMAL HospitaL.—We learn from the British Medical Journal that the Brown institution for Sick Animals is likely to commence at once a work of great public utility. Aided by a handsome grant from the Chambers of Agriculture, Profs. Sanderson and Klein, and Mr. Duguid, will undertake an extended series of observations on the treatment and comparitive pathology of pleuro-pneumonia, an epizootic which commits the most costly ravages among our herds. PAYING A FINE.-A student in the University, says the Edinburgh Courant, who was fined a guinea for dis- turbing his class last week, paid the greater part of it in halfpence, abóut a quarter of an hour being occupied by him in counting over the amount. This singular mode of “serving out” the Professor who inflicted the fine was carried out amid the laughter of the class, by whom the amount had been subscribed. 126 [MAR. 16, 1872. TEEE CI ITTI c. caneroid, Non-re-rangere, Ulcerous Impetigo Rodens, and Non-Ulcerous Impetigo Rodems. Their Differential Diagraosis and Therapy. BY - - M. A. DEVERGIE. Member of the Academy of Medicine, Honorary Physician to the St. Louis (Paris) Hospital, -ſº From the Bull. Therap., Ncy. 30, 1871. Continued from No. 8. This assemblage of facts seems to us to be sufficient to enable the practitioner to make a differential diag- nosis of these diverse affections, and to permit us to turn our attention to the practical side of the question, that is to say, its therapy. But as the disease is very obstin- ate I must, in order to justify the employment of the means that I shall suggest, declare what experience has taught me as to the different causes of its forms. I have never found any connection of effect and cause between the two forms of non-ulcerous impetigo rodens and syphilis, or scrofula, while to these two causes is most often to be attributed ulcerous impetigo rodens; not only syphilis acquired long before by the patient, but also hereditary syphilis. Just as it happens that by hereditary influence syphilis is changed into scrofula, or scrofulous syphilitic diathesis, so ulcerous impetigo rodens may be a consequence of hereditary syphilis. Not only is this disease directly related to scrofula evidences of the ex- istence of which have been manifested in early life, but also to the lymphatic disposition which has not shown itself by any morbid phenomena during youth. It has often been impôssible for usin any given case to determ- ine a priori which of these two causes existed. So before proceeding to any local treatment I do not hesitate to give patients a mixed medication, as I have called it, which comprises medicinal agents proper to combat the one and the other cause. This medication is composed of the “tisane de noyer”f iodide of potassium, bichloride of mercury, arsenic and cod-liver oil. In the way in which these agents are prescribed they do not destroy or neutral- ize each other, and they are given in small doses, incapable of injuring the health yet capable of affecting a cure. It is not in fact large powerful doses that produce the best effect upon chronic diseases, but prolonged treat- ment with small doses. It was this that Chomel brought out so strongly and with so much reason. In anti-syphilitic treatment, for example, large doses become hurtful before complete cure is effected, so that patients cannot continue the treatment more than a month or fThis tisane de noyer is a preparation of the juglans regia; which lat- ter is by the French highly esteemed in the treatment of scrofulous af. fections. The tisane is probably the infusion of the leaves (2 parts to 100), though I have not been able to ascertain the precise formula. [Trans.] a cure and destroying the syphilitic poison. opinion, held for a long time, is a cause of want of suc- six weeks; a time sufficient for the dissipation of the ex- ternal manifestations, but not sufficient for the destruc- tion of the cause giving rise to them. In syphilitic affections two agents seem to be able to destroy the morbid cause; these are the preparations of mercury and the iodide of potassium, the first employed for the the relief of the earlier, and the second of the later manifestations. It would however be an error to believe that the two have indifferently the power of effecting This cess. It is sufficient to have treated, as has been done for example at the St. Louis Hospital, a large number of cases of secondary and tertiary syphilis, to prove the incorrectness of this opinion, which has however been accepted by all practitioners who have paid but little attention to syphilis in its various forms and on a large scale. Let us see to what practitioners imbued with this false idea have been led. Ricord brought in vogue the protiodide of mercury, in the belief, probably, that it had a double action, that of mercury and that of iodine, which enters into the composition of the iodide of potassium. Gibert has recommended a syrup of iodide of mercury and of potas- sium, the composition of which is a little better, in that it contains a proportion of iodide of potassium capable of dissolving the iodide of mercury, and that is even in excess. But it is sufficient to consider the chemical constitution of these bodies to see that the physicians were completely deluded as to the efficacy of the reme- dies they proposed. In the first place, in the protiodide of mercury the iodine is in a state of insoluble combina- tion. The salt contains only so much iodine as is nec- essary to combine with the mercury, an insignificant quantity so far as any therapeutical effect is concerned; on the other hand, when the iodide of potassium alone is given as an anti-syphilitic there is prescribed for the patient a dose of at least 15 grs. a day which is some- times increased to 2, 3, or 4 times as much. With 3.j of the iodide of potassium there may be made 105.6 grs. of the protiodide of mercury. In the #, 3 or 1 gr. of the protiodide of mercury given to patients there is taken but 1–5th, 2–5ths or 3–5ths gr. of iodine in combination, while in 30 grs. of the iodide of potassium there is given about 23 grs. of iodine. The delusion is altogether in the name, and if the protiodide of mercury bas been adopted by the great majority of practitioners it is be- cause it was brought into use by syphilographers who have founded a school. For myself I do not hesitate to say that the protiodide of mercury is a poor remedial agent, and I have thus expressed myself for a long time, however much I have esteemed M. Ricord and the advances in the science that he has made. This agent is a bad one because it is insoluble, and to combat syphilis there must be daily given twenty or thirty times as much of this mercurial as it is necessary to give of the soluble bichloride of mercury; because again it is not known how much of it is absorbed; because it wº MAR. 16, 1872.] T EHI E3 CT, ITNTI C. 127 often salivates; and because its mode of administration is in opposition to an established precept of the time; to wit: that medicinal agents intended to be absorbed act better the more soluble they are. The syrup of Gibert is preferable because it contains a soluble salt of mercury; its action does not correspond, however, to that of the ordinary doses of the iodide of potassium and bichloride of mercury given separately. These various observations tend to justify the mixed or compound treatment, the constituents of which I have already stated, and which from the mode of its prepara- tion will be seen to fulfill the requirements of a mixed treatment while there is secured for each of its constitu- ents its own mode of action and doses. I have the patient take in the morning an hour and a half before eating, and in the evening three hours after the last meal, a tablespoonful of cod liver oil and follow it with a tablespoonful of the following syrup. - R. Ferri Jodid; 38s. Potassii Iodidi 3üss. Pſydrarg. Chlor. Cor. gr. iss. Syr. Simpl. 3aij. M. There is added to this, Fowler's solution, commencing with one drop morning and evening and increasing by a single drop daily, either in the morning or evening, until the amount reaches ten or twelve drops, six in the morning and six in the evening, continuing this dose without increasing it further. In this syrup the bichloride passes into the state of double iodide of potas- sium and mercury. To effect this change an insignifi- cant quantity only of the iodide of potassium is required, so that the directed 3iiss of the iodide of potassium is not found to be diminished to any appreciable amount. The iodide of iron remains unchanged, and the arsenic passes into the state of soluble iodide of arsenic. To resume; the patient takes then (1;) to combat the scrofu- lous element, the “tisane de noyer” cod liver oil and the iodide of iron in about 3 gr. doses daily, the entire amount of the syrup being taken up in about twelve days. (2;) to combat the syphilitic element, about 14 grs. of the iodide of potassium daily, about 1–16th gr. of the soluble mercurial salt and 10 drops of Fowler's solution. It is well known that arsenic is rightly con- sidered an anti-syphilitic agent in the treatment of the tertiary manifestations. In using these different reme- dies, the patient takes morning and evening a tablespoon- ful of cod liver oil and a cup of “tisane de noyer” with the addition of a tablespoonful of syrup and 10 drops of Fowler'ssolution. The employment of these remedies So varied in their nature and yet preserving in the mix- ture all-the conditions for their mode of action just as When taken separately, does not then present any diffi- culty. I have called this medication mixed or compound because it contains all the elements necessary for meet- ing the two causes which give rise to ulcerous impetigo rodens. It is in this form of the disease that a scrofulous or syphilitic origin may be suspected. When after two months trial of the treatment mentioned no improve- ment in the condition of the diseased parts can be seen, the treatment should be abandoned. Three, four or five months will be required for the producing of a cure in the successful cases. The improvement that takes place or the absence of improvement must indicate the con- tinuance or suspension of the treatment. When the treatment is continued, after two or three months the dose of the bichloride of mercury should be diminished one-fourth and the Fowler's solution may be omitted. It is very rarely that a complete cure of ulcerous impetigo Todens can be secured by this mixed internal treatment. Almost always recourse must be had to cauterization of the indolent portions of tissue that remain, in order to bring about perfect cicatrization. The disease having always existed for many years before it comes under the notice of a physician who knows how to cure it, the tis- sues have become modified in their organization, having been long nourished in a particular way. It is because of this condition, common to all chronic ulcerations, that they can never be cured without the employment of some modifying agent more or less energetic. [To be Concluded.] –mº-º-º- SČHENTIFIC NOTES. Spontaneous Hydrophobia. ...From the London Medical Times and Gazette. In the autumn of last year M. Guillery related an interesting instance of “spontaneous hydrophobia” to the Belgian Academy of Medicine, which is reported in the eighth number of its Bulletin for that year. A vigorous old man, 71 years of age, a tailor by trade, who had always had the best of health, was attacked on February 5, 1871, with pain in the head, neck and tem- poral region, which he attributed to cold. He thought little of it until he found, in the evening, on placing his hands in water for the purpose of washing them, that he was seized with a violent and painful spasm of the throat, and a great repugnance to repeat the immer- sion. Feeling thirsty, he tried to drink some water, tea, and coffee, but at each attempt the spasm returned and prevented him. This state of things continuing, M. Guilery was called to him on the 7th, and found him quite calm, speaking of his malady more as a curiosity than a suffering. He swallowed some meat without difficulty, but dared not appease his ardent thirst. Introducing fluid into the mouth without seeing it, by means of a tube, had also brought on the spasms. Persuaded to try, he managed by an immense effort to get down two teaspoonsful of coffee, but declared that he preferred enduring the thirst to repeating the pain- 128 [MAR. 16, 1872. THE CILITTI c. ful attempt. The mere sight of liquid brought on the spasms, accompanied by paroxysms of intense and pro longed fear. The liquid once removed, he conversed- calmly upon his strange malady. His pain in the head had disappeared; there was no fever or acceleration of pulse, and his tongue was only whitish. On the 8th, the symptoms described were found persisting and ag- gravated, cruel sufferings having been produced by attempting to wash the hands. The only thing the patient could take was a few morsels of bread dipped in wine, which had to be conveyed from behind, so that. he should not see them. Mere looking at a glass of water produced a fearful spasm. . An hour after he died, declaring that the attempt to do this had killed him. No post-mortem was performed. It is quite certain that he had not been bitten by any dog. * —-ºº-o-º---- On the Use of the Hacto-Phosphate of Hime as ann Analeptic MHedicamaeant in Ady Raahmaic Fever agad Îla Cornwalescence. BY DR. R. BLACKE, Laureate of the Medical School of Paris, &c, &c, In a great number of acute diseases, especially in ty- phoid fever, typhus, and certain forms of pneumonia, we often notice a condition of considerable adynamia which takes its origin either in the peculiar character of the malady or in the constitution of the patient, and is constantly attended by a marked rise of temperature. This latter phenomenon may be rationally explained by an unceasing and general process of denutrition of the tissues. And, indeed, it is well known that all molecular changes in the form or composition of the constituent parts of the organism are attended with a disengagement of heat, and that these physiological manifestations are under the dependence of the gangli- onic nervous system. - I was led to the employment of this salt by the physiological study of its action on all living organisms. For it is not only in animals, but also in an equal meas- ure in vegetables, that its action is powerful—since, a long time ago, botanists had stated that the ligneous skeleton of plants contained but insignificant propor- tions of the lime phosphate, whilst this substance was constantly found in the soft and nitrogenous parts of the plants. They had shown that the very existence of albuminoid substances was linked with the presence of the phosphate, and was everywhere found in direct ratio to the quantity of this agent, so that the more strongly nitrogenated vegetable food was precisely that which contained the more phosphates. . They had found out this substance in great abundance in the bud and growing leaves; they had seen it decrease in the fully developed organ, and take its way to the grain, where it became concentrated in view of the fu- ture development of the embryo. It is furthermore known that when a grain is deposited in a situation de- prived of phosphate, it produces a plant the develop- ment of which will continue only until the entire quantity of lime salt primarily contained in the grain shall have disappeared. Now, if we proceed to investi- gate the action of the phosphate in the mineral kingdom, We shall find identical phenomena. . . I may recall the fact that in the pregnant woman we See at the end of a few days the phosphates disappear almost completely from the urine and excretions, where- as in the pelvis and often in the cranium are formed os- teophyta,destined to disappear towards the latter months of pregnancy or the beginning of lactation. It can scarcely be objected that these phosphates are uniquely absorbed for the formation of the skeleton. Boussingault, in a series of exact experiments, which can not be too highly quoted, has shown that young animals take up much more phosphates than is required by the develop- ment of the bony tissues alone. Besides, Boussingault, Lehmann, Mayer, and other chemists and physiologists have shown in these cases also the strict correlation which links the presence of phosphates with that of nitrogenous substances, and the concentration of this salt in all organs which are going through a process of develop- ment, and they have enounced the opinion that phos- phate of lime is indispensable to the organization of albuminoid substances into cellules.* - - In order to obtain a correct knowledge of the action of the lime Salt upon nutrition, I carefully submitted a pigeon to the test of taking food which was almost de- prived of phosphate of lime. It soon lost all its liveli- ness, its appetite, a notable portion of its flesh and Weight, and it excreted more phosphate than it absorbed. At the same time the muscular and fibrous tissues diminished as rapidly as the skeleton. The addition of the phospate to its ordinary food soon brought back the normal condition from mineral inanition a fact which, though well known, had not until now been elucidated; that the vital activity of animals and temperature are proportionate to the quantity of lime phosphate which they contain; so that from the bird to man, and from man to the mollusk, the quantity of this sait follows a descending course. The lime phosphate, as has been seen, plays an im- portant part, after its absorption, and when it is carried away with the albuminoid substances through the cir- culatory torrent into the intimate recesses of our tissues. But that is not its only action. It is found in abund- ance in the stomach, forms an essential part of the gas- tric juice, and its action on the digestion of food is such that Blondlot considers the phosphate of lime to be the truly active element of the gastric secretion. And I may indeed even now state the fact that excitement of * “It has been recognized,” says Lehmann, “that in the inferior animals, in the organism of which carbonate of lime is yet the most abundant mineral substance, the phosphate of lime accumulates in the | situations where new cellules are undergoing a process of development.” MAR. 16, 1872.] appetite and facility of digestion constantly and quickly result from the ingestion of lacto-phosphate of lime. Such is, I believe, the uniform action of this sub- stance investigated in the animal and vegetable king- dom. It is scarcely needful here to refer to the use to which agriculturists have turned these notions in com- posing phosphated manures, and to the success has justified their applications. - How is it that, in man, the same favorable results have not been seen to follow the employment of the phos- phates even in such cases where they seemed to be most clearly called for—I mean rickets, osteomalacia, and fractures of bones? A great many physicians had been led, indeed, to employ the substance in these cases, but never with those marked and precise effects which had been expected. . - - - The failure of these attempts is satisfactorily ex- plained when we observe that the preparation invariably prescribed was the pulverulent phosphate of lime, of which lactic acid is the natural solvent. Now, this latter substance enters only for two thousandth parts in the composition of the gastric juice. It could there- fore transform and render absorbable only a very limit- ed part of the ingested salt; whilst the remainder, dis- sociated, reduced into an imperfect powder, passed with the food into the intestines, and there produced con- stipation, and consequently an arrest of all organic functions, the ordinary result of this pathological con- dition. - - It was therefore necessary, in order to obtain the bene- ficial effects of the substance, to introduce with certainty into the economy, large quantities of perfectly dissolved phosphate of lime. It was in 1868 that Mr. Dusart and myself, after hav- ing investigated with care the phenomena of the diges- tion of phosphate in the stomach, were led to reproduce | a substance representing exactly the composition of a portion of bone, rendered soluble and easily absorbable. I have thought it necessary to enter into all the above details, because the facts which they involve, if they were not unknown, had at least passed without much engaging the notice of the profession, and because there had been no explanation of these physiological results. It seems to me that now it will be easy to understand how in convalescence, and in acute affections of an adynamic form, the functions of nutrition are restored; how, after easy digestion, the assimilation of food is se- cured, and fills up the gaps produced by disease, or ar- rests denutrition caused by grave fevers, substituting in its stead a contrary movement. - - The lacto-phosphate of lime is at once an aliment and an article of food, and a medicament of the highest Value. Its administration cannot, like that of alcohol, produce mischievous consequences, and it never de- presses the nervous system charged with presiding over the transformations which takes place in the nature or form of the elements of our tissues—The Practitioner. Feb., 1872. - T TH. H. C. LINTI c. which | 129 MEDICAL NEws Lessons From Sandriangham. [From the Medical Record, New York Mar. 7, 1872.] It is not often that the management of any medical case assumes the proportions of a public event. When it does, besides the interest of the masses, and the repu- tation of the attending physicians, there are at stake the general standing of the profession, and the rank then assignable to physic among the physical sciences. The case of the Prince of Wales was of this class. gº In order to avóid even the appearance of being in- fluenced by popular and contradictory clamors in a question whose scientific interest is hardly second to the political, we have postponed the expression of some of the remarks suggested by the character of the bulletins of the physicians who attended this memorable case. But now that the public has rendered its ordinary ver- dict: “All is well that ends well,” let us say that all that came from Sandringham was not as well as it could have been for the eminent physicians themselves, nor for the profession at large, nor for the fair name and promotion of medical science. We particularly refer to the sanitary bulletins as not representing accurately the condition of the patient, as virtually and wrongfully ignoring the new means of clinical description whose veracity can not be impugned, and as made up of the flabby expressions of alternate fears and hopes. - - We have simply heard that the Prince was better, worse, recovering, sinking, rallying, convalescing, re- lapsing, and finally recovering. For many weeks after this was all the news given to an attentive world. The prognosis was as wavering, and seemingly as uncertain, as it might have been half a century ago, before ther- mometry or sphygmography was dreamt of Naturally these bulletins, very much resembling those issued from Metz when France had the misfortune of not losing Louis XV., alias le bien-aimé, were soon distrusted, and accused of exaggeration, even of falsehood; and openly said to be calculated in view of manufacturing loyalism, or for the vile object of fostering gambling combina- tions. That men like Drs. Jenner, Gull, and Lowe, whose scientific reputation is so high, could have exposed themselves, and the medical profession as a body, to such impossible imputations, shows that there was a serious misconception of their duties to the science of medicine, and that at a time when they had the whole civilized world for an audience. It seems that the cause of their mistake was the idea that the majesty of the subject precluded the possi- bility of publishing the true clinical record of his sick- ness, as if the disease should behave differently in a 130 [MAR. 16, 1872. TIED THE CIT, IT, INTIC . Prince than in a simple hospital patient. This courtly idea offers the only extenuation for the unscientific character of these bulletins, but is far from finding its justification even in courtly habits and traditions. For these traditions and habits have always been, in case of sickness of a Queen, King, or Crown-Prince, to issue bulletins as complete as the science of the time could afford, and to keep the royal patient constantly in view of some of the high officers of State. And why that publicity of sickness and death; why can not a king agonize quietly ; why must people prey upon his decomposing form by minute reports and by de visu proxies? Evidently because a prince—whatever could otherwise be his individual worth—is a cipher, whose social value is borrowed from the millions stand- ing by him, millions who have never been denied the right to know what becomes of the zero. Therefore we do not hesitate to affirm that, if the physicians of the Prince of Wales in issuing their bulle- tins have literally conformed themselves to courtly traditions, in avoiding or neglecting to stamp these bul- letins with the seal of modern positivism, they have forfeited the confidence of the English nation; they have left the door of their council chamber open to un- true but deserved suspicions; they have neglected a solemn occasion of impressing the people with the pre- cision of the methods of observation which have been substituted for guessing at the bedside; and thereby these eminent physicians have, in no small degree, low- ered, or at least prevented the legitimate rise of, the standard of physic in public estimation. On the contrary, let us for an instant suppose that these eminent men, improving the opportunity actually offered to them by the tradition of all the courts of Eu- rope, would have clothed their bulletins in the scientific form adopted by the medical institutions of London, Paris, Vienna, Berlin, New York; these daily or hourly reports would have been written in a few figures, and summed up every septenary. They could also have been accompanied by a few commentaries, such as es- cape from the lips of a medical man looking at the table of vital signs appended to the bed of an ordinary subject of typhoid fever. In the supposition that these popular and progressive views had prevailed in the judgment of the physicians in charge at Sandsingham, the world would have assisted to a novel and dramatic spectacle. We do not mean the spectacle of the pitiable youth slowly eaten up, then let go by the ulceration of his Peyer's glands—we mean the narration, by telegrams, of the phases of an almost ty- pical case of complicated typhoid fever. Never before would nations have listened to such a tale, mainly told in advance, like a prophecy by the thermometer; never such interest would have been attached to predictions of better or worse, fore-shadowed on the stem of the in- strument, and to the degrees of vitality infused in the patient by tonics or food, and written in the pulse-wave of the sphygmograph. Such a medical problem would never before have been solved to a larger or more inter- ested audience; no better opportunity could have been found to prove to the civilized world how much of a Science medicine has come to be. - . If this mode of bulletins had been adopted—and we firmly believe that Aitken, Sydney Ringer, Wunderlich, or Jaccoud would have carried it out—what an impulse would that lesson on positive diagnosis have given to the profession; how higher would physic have instantly ranked in the estimation of the public; and, to speak but once, like courtiers, what a chance the Prince would not have lost of being as useful and celebrated for his sickness as his father was for his goodness! These are some of the lessons we had, and had not, from Sand- ringham. - E. S. —New York, February 20, 1872. ~. MARRIAGE AND CRIME.-The influence of marriage on criminality is not less striking. Whilst the crimi- nality of single men for crimes against the person is 100, in married men it is only 49, and 45 for offences against property. The criminality of widows and widowers ap- proaches that of celibacy.” Relative to suicide, the author (Bertillon) concludes that this cause of death is reduced one-half by marriage. - - SUCCESSOR. To ZOUAVE,--Mr. Strong an American, has set up business in Marseilles for miraculous cures, like the Zouave Jacob. Mr. Strong refuses payment, and his curative mode consists in laying the hands, etc. An interminable procession of invalids daily wend their way to Mr. Strong’s villa on the sea-side, and the doctors intend to petition against what they call the “thauma- turgist. DOGBERRY-CAL.—“Justices' Justice” has become a proverb. Here is a sample of justices' science:—At Chelmsford the county magistrates declined to grant the use of the Shire-hall for a lecture on the sun, illus- trated by experiments in spectrum analysis, on the ground that the electric light might endanger the safety of the building f HoNORs To DR. GULL.-Sir Wm. Gull, Bart, has been appointed physician extraordinary to her Majesty the Queen. - —-º-º-º- CORRESPONDENCE. * syphilis-Corpuscles.” VIENNA, February 9, 1872. MESSRs. EDITORS: Every chair and every Square inch of standing room were filled this evening at the meeting of the “Gesellschaft der Aertze,” because of the advertised review of Dr. Lostorfer's discovery by Prof. Wedl. Prof. Hebra in the chair. Prof. Wedl, having first recounted the results of the * From the Boston Medical and Surgical Journal, March 7, 1872. MAR, 16, 1872.] T EL ED CT, ITNTI C. 131 examinations of Dr. Lostorfer, and the steps by which they were said to have been reached, stated that he had pursued the same method in his researches, but had failed to discover any corpuscles in the blood of syphil- itics which were not to be found equally in that of healthy individuals. He had easily found bodies, simi- lar to those described by Dr. L. as peculiar to syphilitic blood, in almost every specimen of blood examined, both healthy and diseased. They were round, shining bodies, of less size than the blood corpuscles, and having a slightly bluish-green shimmer. Prof. Gruber (aurist) and Docent Dr. Neumann (dermatologist) saw these specimens, and pronounced them to be precisely similar to the bodies which they had seen in Dr. L.'s prepara- tions. Prof. Wedl had then made a preparation of mistura oleosa, in which the fat drops were finely broken up, and in which, on comparison with the so-called syphilis-corpuscles, the small fat drop could not be dis- tinguished from the corpuscles. This applied only to the perfectly symmetrical round bodies. Besides these, bodies had been described of various forms and in many cases supplied with one or more sprouts; these the Pro- fessor asserted to be “torn-off pieces of protoplasm.” The formation of vacuoles was nothing more than a process of decomposition, in which carbonate of ammonia was formed, and which could be demonstrated any day by adding an alkalito fat, and watching their development in the fat. As to the supposed growth of the corpuscles, this the Professor asserted had not been proved, because Dr. L. had not shown that he had followed one and the same through its various stages of development; more- over, that he himself had watched thes same bodies for several weeks, and failed to note the slightest increase in size. In order to remove the corpuscles which had obscured the bodies in dispute, a stream of distilled water had been passed over the slide, and by this means the corpuscles left alone under the microscope. In con- clusion, he suggested that the fat had been introduced into the specimen by accident, as, for instance, in prick- ing the finger to obtain a drop of blood, a few drops of fat might be easily squeezed from out the sebaceous follicles of the skin, and be brought upon the slide with the blood. Prof. Stricker then rose to combat the scepticism of Prof. Wedl, with a reiteration of the extreme caution used in the tests to which Dr. L. had been subjected, and denied that the Professor could have seen the cor- puscles in question; adding further, that he himself had examined them many hundred times, and while unable to judge of their true nature, was convinced that they were neither molecules of fat nor protoplasmic bodies. Dr. Lostorfer inferred that if, as asserted by Prof. Wedl, the bodies had been observed on the first day after the blood was drawn, they could not have been those described by him, which never had appeared within the first twenty-four hours. He further con- cluded that if water had been added to the preparations, his corpuscles must have been destroyed, because he had proved them to be shrivelled up on the admixture of water, especially in the earlier stages of their existence. Prof. Stricker thought it likely that Prof. Wedl, by his stream of water, had at all events washed away the corpuscles together with the blood corpuscles, and had probably by its medium brought many new microscopic objects into the field. Prof. Wedl replied that the “wet chamber” in which the slides were placed would in any case admit water to the preparation by the well-known principle of the diffusion of fluids, and that the streams thereby pro- duced would effect the same as his method of washing the blood. He also thought that after twenty-four hours the blood corpuscles would have lost their color and might be taken for strange bodies. Dr. Neumann recounted some of Hallier's discoveries of spores indicative of various diseases, and his own ex- periments with the specimens supplied him by Hallier. The foreign and diagnostic bodies he had fully proved to be nothing but decomposed blood corpuscles. He had recently subjected syphilitic blood to constant observa- tion for ten hours a day, and had invariably found the same appearances as in his previous researches. Dr. Geber, the newly appointed 1st assistant of Hebra, had, at the request of the latter, examined a large num- ber of paticnts in the small-pox wards, and found, with the absence of syphilitic symptoms, many of these cor- puscles, in part precisely similar to those shown him by Lostorfer, and in part of a somewhat more bluish- green tint. Moreover, in a dead subject he had found them in great quantities. - Prof. Gruber testified to the exact resemblance of Prof. Wedl’s specimens to those of Dr. Lostorfer. It was finally decided that the matter of testing the possibility of a diagnosis of syphilis by means of these corpuscles should be referred to a committee, and the Chair appointed the following members of the Society, omitting, in accordance with the wishes of those present, all who had taken any part in the discussion of the evening: Prof. Rokitansky (Chairman), Profs. Brücke, Billroth, Reichert, Klob; Drs. Auspitz and Casche. To these was added the name of Prof. Karsten, after much excitement and opposition on the part of some present. - . The report of this committee I will send you as soon as published, and in the meantime thought that an ac- count of the ground taken by the opposing parties would not be devoid of interest to your readers. Iam very truly yours, . JAMES R. CHADw1CK, M. D. —-º-e-º- - * —, MARCH, 9th, 1872. PROF. W. W. DAWSON: DEAR SIR:—I find myself indebted to the Medical College of Ohio, the enclosed sum which please put in your faculty fund. This is not a case of conscience; no crime has been committed, only the writer feels his obli- 132 [MAR. 16, 1872. T EEE C LINI c. gation to this extent. Please acklowledge in Clinic. Respectfully, - R. S. M. [If the writer of the above will send us his address he will be furnished, without further question, with a copy of THE CLINIC]. —-º-o-º- CLRNHCAFL lºg(EMHORANIDA. DIGITALIS AN ANAPHRODISIAC.—M. Gourvat, in the course of a paper published in the Gaz. Méd. de Paris, on the action of digitalis, says: “When digitalis, or digitaline, is administered for some time to a man in full possession of sexual powers, these become gradually weakened, the propensities disappear, formation of the liquor seminis diminishes, and may at-last cease alto- gether. The anaphrodisiac properties of the drug are the secret of its good effect in spermatorrhoea. women, digitalis or digitaline excites strong, regular, and intermittent uterine contractions, and controls metorrhagia; hence digitalis is employed in producing abortions (Tardieu), . It is probable that this drug acts as an anaphrodisiac in women, inducing, by long- continued use, impotence and sterility, appearing also, in their cases, to interfere with the development of the Graafian vesicles; the propagation of species being thus doubly retarded.—N. Y. Med. Rec., Mar. 1, ’72. —-º-º-º- IHOMIE NEWS. THE SPRING COURSE opened out yesterday with an introductory by Prof. Conner. THE ACADEMY bristles with new life. The valedic- tory of the retiring President Dr. Comegys and the salutatory of the President elect Dr. Graham were both delivered at the last meeting. The evening was made historic further by the lecture of Prof. Brown-Sequard | which is presented in this issue. THE LECTURE of Wednesday last at the City Hospital before a crowded amphitheatre will appear in full in the next Clinic. • MARRIAGES OF THE DOCTORS.—Prof. Esmarch of Kiel is to marry the Princess Henrietta of Schleswig–Hol- stein. Dr. Frank formerly of the British army, now of Nice has recently married an English Countess and now Prof. Brown-Sequard of Paris has come to our city to be united to Miss Carlisle, one of his former patients in || Paris. THE OvARIOTOMY CASE operated on by Dr. Dunlap of Springfield in the hospital last Monday week, as ex- tensively reported in the daily papers, died on the fol- lowing Friday of peritonitis. The patient had been brought to the hospital from the country. DIED AT HIs Post.—Doctor W. P. Elstun of Columbia, was thrown from his buggy through the violence of an unmanageable horse, in the Twenty-fourth Ward yester- day forenoon, and killed. , Dr. Elstun was held in high favor by the people of this county as a physician and citizen for many years. He settled in Columbia in 1849, and has practiced there ever since. He leaves a wife and child. With || tions on the living and dead subjects. Medical College of ohio. .* sPRING cours E. -*s The regular eight weeks course of practical instruc- |tion for the Spring of 1872 commences March 15. Un- usual advantages are offered this year in the fact that the course will be conducted by the entire Faculty of the College. * - - The course will embrace the following topics: Clinical Medicine—Bartholow. - “. . Surgery—Dawson. - Anatomy Brain and Nervous System—Gobrecht. Operative Surgery—Conner. 4 & Obstetrics—Reamy. & 4 Ophthalmology—Seely. Female Pelvic Surgery—Palmer. Urinalysis—Nickles. - Physical Diagnosis—Cleveland. Fractures and Dislocations—Kearns. Genito-Urin. Dis.—Anderson. Microscropy—Whittaker. -- Prof. Graham will deliver occasional lectures on Clin- ical Medicine and Diseases of the Chest during the pro gress of the Course. - - - The design of the Course is to present instruction in a thoroughly practical manner. Physical Diagnosis is to be demonstrated in the hospital wards; Operative Surgery, Operative Obstetrics, Operative Ophthalmology, and Operative Gynaecology on the cadaver. The Dissecting Room will be under the supervision of Dr. Brown, where abundant material will be provided. Special attention will be paid to the chemical and mi- croscopical analysis of morbid urine. In order to render this course the most practical pos- sible, an opportunity will be afforded each individual of the class to make the various examinations and opera- Regular daily Medical and Surgical Clinics will be held at the Good Samaritan Hospital: Two Daily Clinics will be regularly held in the Cincinnati Hospital, throughout the entire course; and a Daily Clinic will be held at the |Dispensary of the Medical College of Ohio. One hour each evening will be devoted to Recitations on Anatomy, Physiology, Practice, Surgery, Obstetrics, and Materia Medica. : . The eminently practical nature of this course, and its shortness of duration, together with the great clinical advantages presented in Cincinnati, can but commend themselves favorably to the practitioner as well as the student. • FEEs FoR THE ENTIRE Course, $10 As this Course does not count towards graduation, being considered supplemental to the regular winter course, graduates of the College are not required to matriculate. The matriculation of non-graduates is deducted from the fees of the ensuing winter session. Carriage Manufacturer, Nos. 9 and 11 East Sixth Street, bet. Main & Sycamore. I MARE NOTHING BUT PS 7" Cz & S.S. Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur. J . . passed. Of LIGHT FAMILY CARRIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive variety of light elegant designs of different cost and finish. In vehićles especially adapted to PłºśAAS” The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. The superiority of my light gentlemen’s buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price lists furnished on application. References to Dr. W. W. Dawson and all the leading Physicians in the city and fieighborhood. ºur MP, mºſ § to § bul § –1 Fosrº-R's, * 167 EAST 34TH-ST., NEW YORK, By Special Appointment Electrical Instrument Makers to the New York State Hospital for Nervous Diseases, MANUFACTURERS OF PORTABLE ELECTRO-MAGNETIC MACHINES, Portable Galwamic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, 1870, and May 30th, 1871. These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery Fluid. |M|| |||||—|| || ||||}|\, PERMANIENT E ATTERIEs, For Hospitals and General Practitioners, ELECTRODEs. For Eye, Ear, Larynx, Nose, Uterus, Wagina, Bladder, Rec- tum, Feet, Phrenic and Sympathetic Nerves, Elec. trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. IEXTRA w!TS FRONT TH E O PINIONS OF THE MOST EMI NIENT MEM B ERS OF THIS PRO FESS / ON. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “Notuſ: a cAN ExCEED THE EFFICIENCY AND CONVENIENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” g We are authorized by Prof. Hammond to announce ern- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- proved and re-modified Instruments made by our Company. * MEREDITH CLY MUER, M. D., Prof. of Diseases of the Neº- vous System and of the Mind, &c., &c.--" I consider their Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prof. of Surgery, St. Louis:—“In neat- ness, compactness and efficacy, they can not be excelled.” ALFRED C. G ARRATT, M. D., Boston :-"In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” - Similar Testimonials have been received from JOHN J. CRANE, M. D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A. MURRAY, M. D.; CHAS. E. BLUMENTHAL, M. D.; , E. C. SEGUIN, MI. D.; ALLEN MAYNARD, M. D., Cleveland, O.; Dr. C. WAN NIE, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES KELLY, Florence, O.; Dr. JOHN BECKER, Brighton, Iowa; Dr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes- barre, Pa.; JOHN J. CALDWELL, M. D., Brooklyn, and many other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an Electrical Instrument for medical purposes. CALL OR SEND FOR CIRCULAR AND PRICE LIST. IE2_A_TIEI, NTT § 2. § sº O {O Are furnished account. I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMES A. FOSTEE., 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cincinnati, Ohio, or 172 Jef- ferson Avenue, Detroit, Mich. Officers and Soldiers on Government SAML. P. THOMAS DE ALER IN English, French and Scotch GOODs, 34 west Fourth Street, crwciww.wrſ. * WILSON BRO'S. IRTS Made to order of N. Y. M. Muslin and 2300 IIEAVY Linen, per dozen - $36 00 w amsutta Muslin and 2100 HEAVY Lin- en, per dozen - 33.00 Wamsutta Muslin and 1900 Linen, per doz. 30.00 | Lonsdale Muslin and 1700 Linen, per doz. 27.0) First three qualities have ALL LINEN Cuffs and Neckbands. At above prices Cuffs are attached. Same quality of our own manufac- ture, ready-made, $3 per dozen less. - Perfect satisfaçtion given or money cheerfully refunded. - Also import and Manufacture Men’s Furnish- ing Goods. - Pike's Opera-House, Fourth street, Cincinnati; 931 Wabash Avenue, and SS West Washington Street, Chicago. CAMARGO MANUFACTURING COMPANY, MANUFACTURERS AND IMPORTERS OF AND . Window Shades, &? Wasz' AWoLºziz Szºnºr, CINGINNXT, 0. H. H. BRENEMAN, Proprietor, º M A F K TVA IN'S NEW F3 C, O Ex - - IS fºovv READY FOR CA NVASSERS. It contains over 600 pages of read ng matter, with 250 engravings, designed expressly for this work, by the best artists in the country. Agents now at work upon, it are meeting with unparalleled success. . A gents at Circleville, O., reports 25 orders in 2 days; one at Louisville, Ky., reports 175 orders in 8 days; one at Middletown, Conn., reports 200 orders in 12 days; one at Cincinnati, O., re- ports 250 in 12 days. Early applicants secure choice of | territory. For circulars, terms, &c., address NETTLETON & CO., 161 IElm Street, Cincinnati, O. BASCOM & CARRENTER, Stationers, Printers Blank Book Manufacturers, 136 VINE sº DEREET, SNSASNN\\\\p E. D. ALBRO & BRO. IMPORTERS AND MANUFACTURSRs of FOREIGN and DOMESTIC WOODS In Veneers, Boards and Plank, fºr ſaint-Maºri', 'al-Bullier'anišiair-Blileº's, The only house in the Western country that saws Spanish and Mexi- can Cedar for Cigar-Box Makers. We import our own wood direct, and can sell at prices to compete with any and everybody. Also saw and keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. office and Warerooms, 136 and 138 West Second Street, Weneer Mill, 507, 509, 5ii, 513 & 515 W. Sixth St., CINCINNATI, i. - ºze= Jºe: : Ež - ºr=-3. :-----e.g lſº g g ºù; |##### sº { § º i # # #######|| If *-ºs | ift iſiº: º | #|iſſ ... º # # # w | # | § † | | º º!!!"; ſº §§ † º º iſºlſ|| #| |:; ſºft | gift Tººgº § 2 º'. # 3. Bºrº R- º 3: º |ff j. ºft $º: Wiś |\. pºse=s # * , E2EZE . 㺠Fº# &= - ºf ºº }. º 㺠ɺs jºjº §§ | Žiž % gº % % % Z. º §§ 2’ Eº 2, 4%%. %2. #3%%:#7 ãºft# * - #3% ºf S.Šºšº § %; % % £º Zºr ..ºvº sº tº š%:=’ Nº. §§§§ Es: ;:SSº % % %22&f=- #sºsºsºftºff ==s===sgº? * GOOD sa MARITAN Hospit. AL. The GOOD SAMARITAN IIOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner of Sixth and Lock streets. pointments of a First-class Hospital. It is handsomely furnished throughout, and is provided with all the necessary ap- Porticoes, with commanding views, surround the whole house, and wide halls and abundant windows secure that full and free ventilation which is so essential to health and comfort. Service is furnished by the SISTERS OF CHARITY, Under the Superintendence of the well-known SISTER ANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. The regular Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each Professor presiding over his own especial department. of the city any physician of their choice. Patients may, however, select from the regular profession The GOOD SAMARITAN HOSPITAL presents extra inducements to Invalids throughout the State as a safe and quiet asylum in any case of protracted illness, or in cases, more particularly, requiring Surgical Operation, where some stay is necessary in after treatment. ; Rooms vary in price, according to the character of appointments necessary and service required, ranging, in general terms, between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand ot service. 63;" Address, SISTER ANTHON.Y., Hospital Of the GOOd Samaritan, Corner of Siacth and Lock Sts., Cincinnati, Ohio. wo. 27 west Fovara scºrer, PIKE's OPERA HOUSE BUILDING, Importer and Dealer - Diamond and Gold Jewelry, - Watches for Ladies and Gentlemen, . . . Sterling Silver Tableware, - - . Bronzes, Antique and Modern; • Marble and Bronze Clocks, Marble Statuary, G E N E R A L L Y. & , twº s G . ſ º rº-º-º-F. ºw- cº-F * - c. , sº tº sººf. Nºnºvº Q º - ºf * - ºSS ſºlº S.A.S.T.Mº. sººººº-ºº: tº nº wº | º - - º º w ww. te *2 FT - cº- º ...] [2 º º º: º: ------it-s-s--- : a -jī:#;| Pººl * * | - ... . . ." ;:1: ". -* … . . . . #: |-.” Jºi. (ºf d º: ; ; ; • Wºº & - *g # -- - * * * if %$2. S-I; Fº º?. ... * * * * ſ !" - ". º º - ... ." * … ." ºft. ºil. º : Hºlº. Hſil: -º-ºº!}|| - “H”. “l-Hilº 'liº. . . . iiiii.;; ºº::-}|, - !"M}}}} | =º NIPS - ... " ...~" . : Hiſ ºw * ." - * * --- -E ºf sºjº &= w F- 2 : . | *** * . . º ..** * * * * ... tººl, º -r: .4% •=- ºffl * *- w *- º - - ºsº - S. … §§ - - jº • I-> * > * --- | F. "... - “... " " . º .. : ' '...} | . ===- • * j, Hºº. E. - Hº: * * * - H. H. * .." Hº-ji R". Hº E-------- º [. E_E M ===EEE * -º-º-º: * -- ~~~3° ºf ºº.” # tº ºn CINCINNATI. IF. A. C. TCſ L T Y - J A M ES G R A H A M, M. D., DE AN, IProfessor of the Theory and Practice Of Medicine and Clinical IMedicine. W. W. DAWSON, M.D., ROBERTS BARTHOLOW, M. D., Professor of Materia Medica and Therapeutics. Professor of Principles and Practice of Surgery and Clinical Surgery W. H. GOBRECHT, M.D., C. D. PALMER, M.D., Professor of Anatomy. Professor of Medical and Surgical Diseases of Women. P. S. CONNER, M.D., T. A. REAMY, M.D., Professor of Surgical Anatomy. Professor of Obstetrics and Diseases of Children. W. W. SEELY, M.D., JOHN L. CLEVELAND, M.D., - Professor of Diseases of the Eye and Ear. Demonstrator of Anatomy. SAMUEL NICKLES, M.D., CHARLES KEARNS, M. D., Assistant to the Chair of Surgery. Professor of Physics and Medical Chemistry J. A. M. E S T - W H ITU T. A. Ex E IR, , Frofessor of Physiology and Secretary of the H'aculty. Janitor, College Building, Sixth St., bet. Vine and Race. T. LOUIS BROWN, Prosector of Anatomy. Printed and Published by Noh RIs & M URBY, Medical College of Ohio Building, Cincinnati, * {i $ +ºf THE STUDENT'S SUPPLEMENT. Practical Instruction. “Is it advisable to attend the spring course?” This question is frequently asked, and merits careful consideration before sit is answered either by the student himself or the physician to whom, perhaps, the inquiry is addressed. Every right-minded student and practitioner recognizes that the period which custom has established for the undergraduate’s training is a very limited one, and the consequent neces- sity of using all of that limited time to the best advantage. It becomes, then, a question of very great impurtance in which way will the spring months of each year be most advantage- ously spent: in reading in the preceptor's of: fice, or in attending the “spring course.” At best, if the preceptor has the time and inclu- nation to do his lull duty by the student, the latter can only receive the 1esults of the pro- ſessional thought, study aud experience of a single individual, and watch the cases occurring in a practice limited to a district of a few miles radious. Anatoin.cal study must, of necessi- ty, in the vast majority of cases, be limited to reading books and examning dry bones. In almost as many cases, surgical study must be limited to reading, and the occasional opening of a boil or putting on a baldage. The conduct of a case or two of obstetrics will probably include all the practical midwifery training the office student whll receive. Now, if by this sort of training, valuable as it is, necessary as it is in its place and to its proper extent, the intervals between the win- ter courses of lectures are filled up, the newly- created M. D. will enter upon his professional caneer almost, if not altogether, wholly igno- rant of the mechanical part of his life-busines which, if he is to succeed, he must learn, . which, for his own good, and the good of his patients, he ought to know considerable about before he is pen mited to proclaim himself a doctor. Will he be aided in acquiring this most necessary knowledge by attending the Spring course : What is the scope and inten- tion of this spring course 2 Is it to give to the Student a repetition of the winter course, and that, too, a repetition limited, trite in the number of subjects considered and the tho- roughness with which they are considered Not at all. Its object is the enabling of the Student to learn for himself, under proper di- rection, how to auscultate the chest and to recognize and distinguish normal and abnor- mal sounds; how to make the various gynae- cological and obstetrical examinations, and to use the instruments that may have to be em- ployed in the treatment of cases in these de- partments of practice; how to perform required 9perations in opthalmology and general sur- §ery; how to examine tissues, healthy and diseased, and excretions, physiological and Pathological in character; in a word, to train Practically the eye, the ear and the hand. And while this training is going on the student has the advantages of hospital and dispensary clinics and the theoretical knowledge prev- *sly or at the time acquired is fixed in mind by º quizzes” and recitations. Is it not, then, advisable to employ two months in the Spring Of *h undergraduate year in attending the Spring course ? * ºmma--- The History of Anatomy, In the Medical School of Alexandria, found- ed by Ptolemy 1 (320 B.C.), human anatomy seeins to have found its first asylum. Celsus tells us that the reaction was so great that Erasistratus even opened the bodies of living meu condemned to death, that he might more accurately study the uner workings of the systein. This is, perhaps, about as true as the remark that Herophilas was able to recognize in the pulse of the king's son his love for his stepmother. No opportunites were offered in the rest of the world. Galen was compelled to travel from 1'ergamus to Alexandria to see a perfect skeleton. It is highly probable that he never opened a human body, as his descrip- tions of organs are only those of the ape and dog. The age in which he lived, says the his— torian, offered yearly thousands of human lives to the caprice of the Roman people, and their cruel eluperor cast them even as prey to the wild beasts of the Collis.um, but would no. grant one single dead body to the study of science. f Still as late as the seventh century the ex- amination of the dead was made a penal offense According to a passage in Cassivodorous, a Benedictine Monk and physician of that time, guards were placed in the different cemeteries to prevent the desecration of graves and all secret exhumations, and the Salisch law lor- bade any intercourse with any one who had even participated in robbing a tomb. With Mundinus (1290), Professor at Bologna, anato- my celebrated its second birth. He ventured to use the human body, and dissected two fe- males before his class. These he was coin- pelled to preserve unitil every organ and mem- ber was properly displayed To do this he adopted the same expedient which is still le- sorted to when material is scarce – he exhibited the intestines and internal organs, brain, mus- cles, bones, &c., in the order in which they first decay. But this happy inaugural to the science of anatomy was destined to meet with a sudden extinction. In the year 1300 Boniface III. pub- lished that celebrated Papal bull, which pro- nounced sentence of excommunication upon any one who dared to dissect a human being and boil asunder his bones. The occupation of the Benedictii,e monks with the science of medicine and its effect upon their religious proclivities, as injurious to pro- longed fasting, prayer, &c., seems to llave been the occasion of this famous document. The first dissection in Vienna, was held in 1404, by Galeatus of Padua. It was performed in public, and lasted eight days. Female bod- ies were not admitted until 1452. As a curios- ity, it may be mentioned that the body of a thief hung upon the gallows, was delivered over to the doctors and was by them restored to life. In 1492 this reanimation was repeated in another case, when the law was passed that bodies should hereafter be followed by the oi- ficers of justice to see that these attempts were not repeated. Sylvius soon after erected an amphitheater at Paris, that students might obtain a better view. In Andreas Vesalius (1514) anatomy receiv- ed its greatest reformer. His enemies, the Catholics, called him the luther of Anatomy, Such was his zeal for his study, that he was the subject of most violent persecution. Ac- cording to his own conſession, he did not hesi- tate to invade the sanct ty of the graveyard, and he habitually stole the bodies of criminals executed on the gallows or at the wheel Fi- nally he was connpelled to flee from his native country (Belgium) and betake him, self to Paris. His accurate acquaintance with even the smallest bones of the Wrist and ankle (he could distinguish them by touch with blinded eyes) gave him a corresponding reputation, and, as always occurs in such cases, excited in others a corresponding envy and persecution. He visited Italy, taught in all her universities, and was finally appointed by the Republic of Venice, Professor of the University of Padua, at the unprecedented age of thirty-three. His enthusiasm never ceased, and it finally awak- enca for him such intense hatred at Rome that he was ordered to make a pilgrimage to Jel u- salem in expiation of alleged crime. Having resigned his position and burned all his papers under the same cruel order, he set out upon his journey. On the return he was shipwrecked on the coast of the Island of Zante, where his body was alterwards found and recognized by a goldsmith, and placed in the Chapel of the Holy Virgill. The report that his punishment was ordered because he had opened the body of a lady of the Court at Maurid, while the heart was still beating, is but one of the cabals of his enemies. It is, however, true that his great work on Anatomy was subjected to cell- sorship of the linquisition by the older of Charles W.; and the question whether it was per missible to open dead bodies was asked dur- ing his time of the theological faculty of Sala- manca. The question was discussed with more reason by these learned gentlemen than that of the efficacy of baptisiu in the womb by means of Syriuge by the profound theologians of Sorbonne in 1733, for it was answered that the Bible did not prevent dissections. The portrait of Vesalius now hangs on the walls among world-renowned collections of the Pitti Palace at Florence, and his life has been written by Burggraeve. His restless, zealous spirit was inherited by lis pupil, Fallopla, who even excelled h m in the correctness of his drawings of anatomical subjects. But Fallopia stained his reputation by experimeuting upon criminals with diffel ent kinds of poison. Prejudice and superst tion still held sway during the follow ing hundi ed years. Nicko- laus Stein was obliged to reliounce the Protes- tant religion. Rolfinc of Jena excited such a fear among the people that many a poor crim- inal begged of lus Judges that he might not be “Rolfincked” after his death. Albrecht of Gottingen, who was obliged to dissect in a dark cellar near the fol tress door, was finally uenied even bread and water by the people of the town. Everywhere oppon- tunities were denied. How strange it now seems to read the boast of Paaw, that he was able to hold two or three dissectious every year. On account of this lack of material, wax preparations wel e made in great quanti- ty, and at enol mous prices. Such collections still exist at Florence and Vienna, and even now there is a village in F1 auce where nearly every inhabitant finds support in their prepa- lation Women and girls an e likewise engaged in numbers, and many specimens are wonder- ful models of beauty and accuracy Diffel ent organs and parts of the body were also preserved in alcohol. Peter the Great bought the collection of Ruysch (or 30,000 gul- dens; but a great part of it was destroyed on the voyage to St etersburg, as the sailors drank up the liquor in which they were con- tained. Quite recently a similiar accident de- stroyed a fine collection en route for Russia, and since this occasion, the precaution is al- ways taken to add a little con losive sublimate to the preserv lug fluid, which (\en the Scyth- ian stomach will probably respect. 'I he finst dis-ection in America was made in N. Y., in the year 1750. Very likely the first public dissection in Cincinnat] was held in the Amphitheater of the Medical College of Ohio, over fiſty years ago. GUIDE TO THE LECTURES IN THE COLLEGE AND HOSPITALS.* MON DAY. TUICSDAY. WEDNIESI) AY. THURSDAY. FRIDAY. SATURDAY. HOU R. 9 in * * - º # Reamy. Seely. Cleveland. Whittaker. Conner. Palmer. Dispens'y - —w- ; - GOOD SAMARITAN 11–12 Kearns. Reamy. Kearns. Cleveland. Whittaker. HOSPITAL. *----- - - -º-º- Tate. 12---1 Gobrecht. Conner. Palmer. Conner. Anderson. Seely. * GOOD SAMARITAN & 3—4 Nickles. Whittaker. HOSPITAL. Nickles. Seely. pººr 7 1-, i. *-- --- Dawson. 5–6 Whittaker. Cleveland. Seely. Conner. Recitat’n Reamy. Nickles. Bartholow. Palmer. Anderson. 8–10 Practical Anatomy. * The Order of Lectures at the Cincinnati Hospital is not yet announced. G2: Xo->=- THE SPRING SESSION OF 1872. A Bird's Eye View of the Course. Modern medicine is characterized by its positivism. The application of the various instruments of preci- sion, as they are called, the microscope, ophthalmoscope, thermometer, etc., enable the physician skilled in their use to make his diagnosis sure. The vague, indefinite, and unmeaning terms of even a decade or two ago are rapidly becoming obsolete in medical vocabulary. In their place is substituted that more exact phrase- ology which describes and locates with precision the organ affected and its disease. This is, of course, the natural consequence of the more exact knowledge which is now possessed—the result of the more direct means of investigation employed. Uncertain hypothesis, thus, has given way in great measure to actual demonstra- tion. The great advance of medicine as a science, in modern times, is but the legitimate triumph of experi- mental demonstration over what used to be called rational deduction. This revolution in the method of the study of medicine calls for a like revolution in the method of instruc- tion. Witness, now, the really wonderful effects which have followed the radical change in the manner of teaching and studying the languages, both ancient and modern. But a few years ago the student was com- pelled to pore over the dry rules of grammar and memorize pages of words; indeed, the grammar and the dictionary were his only aid. Few, there were, who ever attained proficiency. Now the whole system of inn- partation is different. At first but a few common, every-day words are learned; then follows a short practical exercise for translation, which is to be written down; and then a still more practical effort at conversation. To-day fluency in one, even several foreign languages, is common everywhere. It must certainly surprise those not familiar with the fact, to learn that there has been until recently but little, almost no change in the method of instruction in medicine for the past fifty years. There is offered to the student the same round of didactic lectures from morning till night. In many cases there is not a single demonstration made, not a point offered any where to address any other sense than that of the ear. The evils of such a method are only too apparent to any board of examiners; and painfully apparent they become to the student himself when he first attempts the execution of those precepts which his memory may still have pre- served Long ago foreign schools became impressed with the necessity of this change. Long ago the prac- tical method was adopted, and the benefits and attractiveness of such a system are at once evident in the crowds of students from all parts of the world that throng the private courses of the foreign universities. Two years ago this same plan was adopted in the Medical College of Ohio. Feeble as the effort may have been at first, it was, nevertheless, the first course of practical instruction ever presented in the United States. So successful it proved in the numbers of students attendant, and the enterprise and enthusiasm exhibited, that it has now been adopted as a fixed feature of instruction supplementary to the regular winter course. As already intimated, the distinctive feature of this course is its eminently practical nature; in detail, it is a model of the short courses of private instruction in all the foreign schools. There is first every provision made for clinical instruction. The large wards of the Good Samaritan and City Hospitals are constantly filled with patients with every possible malady. The dispensary of the College abounds in that class of cases more par- ticularly which first present themselves at the office of the young physician. The whole of Wednesday and Saturday afternoons are to be devoted to the Good Samaritan Hospital, while daily clinics will be held in the wards of the City Hospital. The dispensary is open from 9–11 every morning, and here more especially is opportunity granted for the individual examinations of every kind of disease. In the various operative courses every member of the class is to be permitted to make personal inspection, application, and manipulation of the various proceedings taught. In operative surgery, for instance, every amputation, ligation or operation of whatever nature, is to be thus repeated by each member of the class upon the dead body. In operative obstet- rics the female cadaver is also employed with the dead foetus; and here, too, the student is to be personally drilled in the detection of the various positions and presentations, as well as in all the operations of mid-wifery, foiceps application, version, craniotary, cephalotripsy, etc., etc. In the course on urinalysis, specimens of morbid urine are to be placed in the hands of each member of the class, and he is to be taught the method of detection and recognition of the varions conditions of disease. These are but a few points selected from the course in more specific illustration of its peculiar nature. In addition to these various operative and demonstrative courses, recitations are to be held, one each evening, on the various departments of medicine. In this way, and only by Home such means, may that drill and discipline be obtained which is an essential pre-requisite to accurate and fixed knowledge. These, then, are the advantages in brief which are offered in what is known as the practical system of instruction. No honest, earnest student will fail to embrace them; none but that will appreciate them in practice at their worth. w - THE CLINI C. PUBLISHED EVERY SATUR DAY. sº *:::: *** * T E R M S-$2.00 a Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editer i . . . . * *s-All Communications relating to Băsiness, Substriptions, Advertisements, etc., to the Treasurer. —£4— † = & —º- º * .* ---. Vol. 2.- * ~ * C IN C IN N A TI, M A R C H 23, 1872. ** - No. 12. JAS. T. VV HITTA KER, M. D. tº º º Editor. No. 101 West Ninth Street, Cincinnati. JASSO cI.A.T.E. EºPITOER.S.- . W. W. Dawson, M. D. THAD. A. REAMY, M. D. P. S. Con NER, M. D. C. D. PALMER, M. D. ! W. W. SEELY. M. D. SAMUEL Nickles, M. D. CHAs. KEARNs, M. D. JN6. L. CLEvel. AND, M. D. Roberts BARthonow, M. D. W. W. SEELY, M. D. - - - - - - - - - TREAsunza. No. 118 West Seventh Street, Cincinnati. C L U B R A T E S. 4 Copies to one address $ 7.00 6 66 & & : , 10,00 12 & 6 & & 18.00 C O N T E N T S. . * * *-ºsmºs Page. orticiNAL ARTICLEs The Mechanism of the Production of the Symptoms of Brain Dis- ease, by Prof. C. E. Brown-Séquard, M. D., F. R. S.................. 133. " t TRANsi,ATRox Cancroid, Impetigo, etc. Their Diagnosis and Therapy, by M. A. Duvergie, [From the Bulletin Therapeutique, Nov. 30, 1871]......130 SCIEN" TIFIC NOTES Convulsive Reflex Facial Neuralgia—vesico-Urethral Absorption— Medical Jurisprudence of Insanity—Syphilis in the Ape—The Action of Alcohol 138-141 MIE DICAL, NEWS. A Generous Testatrice—Patriotic—Baby Farms—A Comfortable Practice—Anecdote of Dupuytren—An Epidemic of Icterus— . Cholera—Teaching and Practising....... 141-142 CORRESIPON DENCE A Suit for Mal-practice—Charge of the Judge—A Fair Exchange— A Little Thin * * * 142 C. L.INI ICAI. M. [EMIOLRANIDA Chloral, Clinical and Experimental Researches—Arseniate of Qui- nia in Tetanus—A Quinine Collyrium—Poisoning by Atropia— j. TAFT, The Treatment of Pleurisy 143-144 HOME NEWS T44 The spring course of 1872 Y44. SEVERAL articles of original matter are crowded over this week to give place in full to the lecture of the distinguished stranger still within our gates. The therapy of cancroid and its allied affections, as detailed in the translation of to-day, is well worth a transfer to the physician's note book. The case of reflex glaucoma is in striking confirmation to the views of Brown-Séquard. The note on medical jurisprudence is likewise oppor- tune, as a view in full accord with that so recently ex- pressed in the Academy in a prolonged discussion on The this subject. co.é.IN te CCP- Fashionable *Hatters, IMPoitter:S AND MANUFACTUREIts of ... E.A.B.E.E.S." Fºtºs, 92 WEST FOTTERTEL ST. Opposite Post Officer CINCINNATI. t •wsreelal Inducements to Medical Men- RAVERSoNWOOD ºf Sãº. º - - gº * * * * *= W. TAFT. Editor Derntal Register J. & W. TAFT, TYETNTTIsTs 117 WEST FOURTH STREET, CINCIN NATI, O. A Monthly Journal, : CONTAINING 48 PAGES, Devoted to the Interests of the Dental Profession, Marvin's tºº COID IT ITVTIEEE, OIL O ID O E& L E S S A.N ID IP A. L. A. T. A. IB IL, IE • In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERs & BARTLETT, of Portsmouth, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. y In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachitic Affections, in Chronic Rheumatism, &c. * The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. ~x. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. List of Pharmaceutical Preparations, Jonºv. Irrazºr & amozwan, F.H.I.E.A.D.E.L.F.E.C.I.A. —º- ELIX. PHOS, IRON, QUININE AND STRYCHNIA, ELIXIR OF GENTIAN FERRATED, ELIXIRVALERIANATE OF AMMONIA, (Goddard’s Formuła,) ELIXIR VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, Iron, with Phosphorous and calisésa, FERRATED ELIXIR OF CINCHONA, Iron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK, ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER WINE OF IRON, Citrate of Iron amud Peruvian Bark, FERRATED CORDIAL ELIXIR, ELIXIR CALISAYA BARK, WINE AND BISMUTH, ELIXIR CALISAYA BARK, IRON AND SIRYCHNIA, WINE OF WILD CHERRY BARK, FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, TASTELESS COD LIVER OIL, TASTELESS COD LIVER OIL. FERRATED, BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and sherry wine, ELIXIR WALERIANATE OF STRYCHNIA, WINE OF PEPSIN SYRUPSUPERPHOSPHATE OF IRON. 9 ELIXIR OF BISMUTH, COMP. 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We wish it understood by the Profession and the Public generally that our invariable rule is, to make or import none but the best in. struments. Those in want of any of the acknowledged good aids of vision to imperfect eyes, will always find the best and largest stock of Lenses, Spectacles, and the best models procurable, with pains- taking skill to adjust them to all conditions of sight, at our house. Special attention paid to orders for Fine Microscopic Objects and *rºcopiº Apparatus, Magnifiers and Readers in great varietv. edical Batteries, Barometers, Thermo- meters, Hvgrometers, Urinometers and Rain Gauges, of the most approved coustraction always on hand. All orders promptly and accurately filled. , JAS. FOSTER, JR. . deali ^ F. S SHACKLEFORD, } *** ** JAs. FostER, JR. & Co. S. W. Cor. Fifth & Race Sts., Cincinnati, 0. TXIEvº, S-INT. INAL_A_IEC/SIET’S SS »TRUSSES. if you study carefully the phenomena of arrest of activ- ity of the heart and intestines as first observed by Jaeger, of arrest of respiration by galvanization of the par vagum or after passing carbonic acid gas into the larynx or after direct irritation of the larynx or, finally, after pricking the cord with a pin, you will admit that this cessation of activity starts from the point of irritation. In cases of brain disease, then, we have every variety of symptoms from any lesion, determined only by the part upon which the influence may be exerted. Start- ing, thus, with lesion of any part of the brain we may have a cessation of activity of any of the senses or of speech, or of one or more muscles according, as stated, to the part upon which the influence is exerted. Some time past I was led to believe that the loss of consciousness in epilepsy depended on a local syncope of the cerebral lobes from spasm of the blood-vessels. There is no doubt but that the blood-vessels of the cerebral | Robes do contract and there is no doubt but that such a cause is sufficient to induce loss of consciousness. But this syncope is too sudden to be attributed to the effects of contraction of vessels and consequent diminution of blood supply, hence I am compelled to retraet my for- mer opinion and to admit that here too the loss of con- sciousness is only a cessation of activity. It is demon- strated in some of these cases that there is dilatation of the vessels so that arterial blood flows from the sinuses, proof that the syncope does not depend upon lack of blood. It takes about 8–10 seconds for loss of conscious- ness to supervene after the circulation has ceased. In one case 12 seconds elapsed. In epilepsy this kºss of con- sciousness is immediate, consequently it can not depend upon this cause. - But here I am compelled to stop. I would be glad to continue this subject, may possibly have the opportu- nity of doing so upon some future occasion. May what I have remarked upon this most interesting subject stimulate some younger member of our profession to those further investigations which youth is more capable to undertake. —mº-O-º- THE CAPTURED MEDICAL STUDENTS AT HAVANA.— A correspondent writes that—“The Medical students now undérgoing imprisonment for the desecration of the tomb of Caslanon were removed about a fortnight ago from the city prison, La Punta (the scene of the No- vember massacre), to the villa of the Captain-General, the Molivo del Rey, on the Pasco de Jacon. It is sat- isfactory to know that the students are in excellent health and spirits. Food and cigars are brought daily to them by their friends. They wear the ordinary prison dress, with their hair closely cut, and with their legs chained. The most melancholy sight was to see the fathers and mothers, brothers, and sisters of these boys, who were sitting on rough benches under the Verandah, distracted with grief and anxiety, and whose minds must surely give way; in fact, some have already done so under their cruel infliction. It is considered in Havana that the removal of the students from the com- mon prison is the first step towards their ultimate. release.”—Times and Gazette, Mar. 2, '72. Cancroid, Noli-Me-Tangere, Ulcerous Impetigo Rodens, and Non-Ulcerous Impetigo Rođems. Their HDifferential Diagnosis and Therapy. BY M. A. DEVERGIE. Member of the Academy of Medicine, Honorary Physiclan to the St. Louis (Paris) Hospital, From the Bull. Therap., Nov. 30, 1871. Continued from No. 11. The compound treatment that we have mentioned is only applicable to ulcerous impetigo rodens, especially that of long standing. It should not be employed at the commencement of the ulcerous form nor before there is recognized in the patient certain proof of antecedent syphilis or scrofula. Most often the ulcera- tions in the early manifestations of the disease can be cured by cauterizations; but if they are obstinate, there should be no hesitation in employing the treatment in- dicated. As to the non-ulcerous forms of impetigo rodens, they always yield to cauterization, and do not require any general medication. In my treatise on the diseases of the skin I reported in detail the first case of impetigo rodens that I diagnosed and cured. I will mention here the principal circumstances. A lady acquaintance of our illustrious printer M. Firmin Didot, consulted me through him in 1845. She had in the neighborhood of one of the eyes an ulceration that had resisted all treat- ment. The lady had consulted the principal physi- cians and surgeons of Paris. It is useless to enumerate the various sorts of pommades, lotions and local applica- tions of all kinds that had been prescribed for her, as well as caustic and more or less superficial modifying applications. She showed me a list of prescriptions of diverse natures and origins. In the presence of such a past I postponed the case on some pretext or other, and reflected upon the means that I should make use of to effect a cure. I had already commenced a comparative study of caustics and their effects; I had come to have a decided preference for the chloride of zinc as being a powerful modifier, and one that could be regulated at will by conforming to the mode of employment in- dicated by Canquoin, who introduced it into therapeu- tics; whence the name that it bears, that of Canquoin's paste. The efforts that have been made since that time to vary the use of this caustic, and the daily employ- ment that I have made of it, have confirmed my early preferences. It is a dry caustic, i. e., it causes a dry eschar sometime after its application to the skin, one that does not attract moisture from the atmosphere nor give rise to any secretion or suppuration, at least not generally. The eschar, drying upon the cauterized MAR. 23, 1872.] TEEE CI.INI c. 137 part, remains adherent for twelve or fifteen days with- ont any dressing, and falls off leaving a very clean cicatrix. This cauterization does not necessitate any dressing; the applied caustic should be let alone. It gives rise half an hour after its application to an inflam- mation that increases for twelve hours, causing a swelling more or less extensive of the surrounding parts, the attending pain being very bearable and the sens: - tion subsiding after the first two or three hours. These painful sensations are so bearable that no patient has, refused to be cauterized a second time when this has become necessary. One remarkable thing is that the swelling, whatever its extent, even when it shows itself in an usually high degree, (and in this respect I may say that I have seen some rare cases in which the patients believed that they had taken erysipelas,) never causes any disturbance of the general health of the patient, and completely subsides in forty-eight hours, without leaving any traces, or necessitating recourse to emollient applications. These inconveniences that I have described are the exceptions. In the generality of cases the phenomena of cauterization are of no import. ance. Finally when one well understands the manage- ment of this caustic and the proportioning of the thick- ness of the layer which is to be applied to the parts to be destroyed, he is never obliged to reapply it to the same point, so that he may proceed from one point to another in such manner as to successively attack the whole surface of the wound, multiplying the cauteriza- tions and benefiting by them all the points attacked. In employing this caustic two preliminary measures must be attended to: 1. There must be procured chloride of zinc that has deliquesced under the influence of the humidity of the atmosphere. 2. There must be used in making the paste excellent wheat flour. In the shops chloride of zinc is found in two states fused in a solid mass or crystallised. In either state it has a strong affinity for the moisture of the air, and little by little becomes liquified. But the fluid which is formed from the fused chloride of zinc is of an oily consistence and more active than that which results from the exposure to the air of the crystallized chloride of zinc. The first then should be preferred. When the physician does not find this liquid layer fully formed in the bottle, he must then procure it by making an opening in the cork of the bottle which contains the solid chloride, and placing the bottle in a damp place ; he will thus obtain in the course of a week the liquid necessary for pre- paring the paste. The same results will not be secured by adding water to the solid chloride; the salt will be in part decomposed, and there will never be obtained the oleaginous liquid which I have before mentioned; it will not then enjoy in the same degree its caustic property. Nothing is simpler than the preparation of the paste, which results from the mixing of good flour with the chloride. Take a saucer or small cup; place in it a drop of the deliquesced chloride of zine; near by a little flour; then with a flat bladed instrument such |as a spatula or better a sharp pointed knife, work up together, little by little, the flour and chloride until a mass is obtained of a consistence more or less thick ac- cording to the intensity it is desired the caustic to have. It is the density of the paste that gives a measure of its mode of action. But in making this mixture, one must not lose sight of the fact that the paste once made afterwards becomes slightly more liquid and loses a little of its consistence when applied to the diseased part, and as it ought to keep in place without the use of any retentive apparatus it is necessary that it should be prepared a little thicker than it is desirable it should be when in use. It is not solely the consistence of the paste-that gives it its caustic power, but also the thick- ness of the layer applied. This is a matter of habit and practice. But the physician in using it should not lose sight of two factors, the consistence of the paste and thick- ness of the layer, if he would not have the effect exceed what it is desired to produce. The application to the affected part may be made by means of the instrument used in mixing the paste. It is sufficient to spread evenly the layer as well as to limit its circumference with the point of the instrument to cause as strong a cauterization at the circumference as in the centre. As soon as the paste has been applied its surface will be seen to become glistening from the little moisture that is absorbed from the air. If the paste runs and spreads it is because it is not sufficiently consistent. It should be removed with a piece of linen and a new application made. Then it should be left to itself; it sets in place, little by little dries, in some hours becoming firmly attached to the diseased tissue, which it attacks in all parts. The chloride of zinc is one of the least painful caustics. Applied as directed it adapts itself to all the conditions of the skin, according to the thickness of the layer. On this account and in the majority of cases, particularly in the forms of disease which we have described, where it penetrates to all parts, it should be preferred not only to other caustics, but filso to the solid preparations in the shape of stick or otherwise as proposed by M. Filhos; not that we would wish to disparage the advantages of these modes of using it, which have their special uses, particularly when it is desired to circumscribe tumors, and to remove them by means of caustics in stick or layers introduced into the depths of the tissues. It is important to add to the ad- vantages of this paste and this caustic that it leaves only very slightly apparent cicatrices, and those very rarely attended with deformity when the caustic has been properly applied. I recollect destroying in this way seven or eight tumors of frambaesia seated upon the face of a young girl of eighteen, without there resulting any very noticeable cicatrices. This result will not always be secured unless the patient never touches the eschar before it has spontaneously fallen off. For this reason I have several times had patients, even adults, wear a mask of very flexible iron wire similar to those sometimes placed on the arms, in order to protect the $38 [MAR. 23, 1872. * face against the rubbings which may involuntarily occur during sleep. It must be understood that Canquoin's paste has no action upon those parts of tissue or of a wound which are covered with a crust or the epidermis. Care must consequently be taken before applying it to secure the removal of such crusts. A small flaxseed poultice on the diseased surface for an hour or two will secure this result. I have entered into these details in order that there may be secured the good effects that may be obtained by the employment of this agent. If however, one compares Canquoin’s paste with other caustics, it will be seen that aside from the chloride or butter of antimony all the others give rise to eschärs more or less moist or causing secretion. Often it is necessary to envelope them and keep them in place by a layer of gauze Ör amadou or diachylon, etc. For the chloride of zinc no retentive dressing is necessary. As to the non-ulcerous impetigo rodens, a single applica- tion of the paste is ordinarily sufficient to cure it. In fifteen or eighteen days the patient is wholly rid of a disease that has annoyed him for many years. - A remarkable fact, and one that well shows the nature of the affection, is the appearance in persons somewhat lymphatic of a secretion around the cauterization which resembles in all its characters ordinary impetigo. It is almost painless, concrete and crystalline like impetigo, the crust which it forms drops off with the eschar. Such are the teachings of 3, thirty years practice respecting these various forms of disease. I have been led to bring together all the fruits of my experience and impart them to my fellow workers, convinced as I am that in taking notice of the facts pre- sented in this article they will thence derive marked advantages in their practice. The forms of disease that I have described (the treatment of which I have stated) are not rare. They are diseases most usually but little understood by physicians; and it is this that has led me to call their attention to this subject. -- - - sº- c, -º---— scIENTIFIC NotEs. wº t! O N V U L S I W E FA CIA L N E U R A L & H. A. Followed by Glaucoma, its starting Point being a “Peripheric Morbid zone.” Entire Relief of the Pains and Convulsions by Division of the Infra-orbital Nerve. IBY -- PROF. CH. ABADIE, (PARIs). An Abstract from the Journal d’Ophthalmologie, Feb., 1872. The author claims that the case is one of the greatest interest as regards the general pathology of the nervous system as well as ocular pathology. It is a clinical confirmation of the beautiful experi- * ments in physiologico-pathology of Hippel & Grünhagen upon the production of glaucoma. The subject was a woman who consulted the author in 1871 for a painful affection of the face which had been followed by a comi- plete loss of vision. * The disease began in 1863 under the form of attacks of pain in the left side of the face. - - For the first two years the neuralgic attacks only occurred at intervals of two or three days, later on, every day, and for about a year, twenty or thirty times a day. . . The patient presented the appearance of an extremè sufferer. - The violent contractions of the muscles of the left side of the face had produced large wrinkles in the skin, deviation of the angle of the mouth and nose; giving to the face the appearance of monolateral facial paralysis. The left eye presented all the external signs of chronic glaucoma. - - - No perception of light. The right eye was atrophied. The patient simply sought relief from the excruciating pains, which had lasted for eight years. - All the branches of the 5th pair seemed to be in- volved. - . - There were violent convulsions in the muscles of the left side of the face and head. Sometimes, during the more violent attacks, the muscles of the limbs were contracted. So there were veritable general convulsions, though no loss of consciousness. -- The patient presented all the characteristics of the epilepti-form facial neuralgia as described by Trousseau. A careful examination excluded the idea that the origin of the trouble was glaucoma of the left eye. The pains began before sight was affected, and were wº gº located at first not in the eye, but in the skin of the lips and of the malar region, afterwards in the upper and lower jaw. - - Later, ciliary pains, radiating to the brow, began in the eye, then the sight began to fail and finally disap- peared entirely. - Three years later violent pains appeared in the right eye, followed by ulceration and perforation of the cornea and complete destruction of the eye in three days. Numerous observations have established for a long time that irritation of the branches of the 5th nerve may produce glaucoma, and the articles by Hippel and Grünhagen (in Graefe’s Archiv, 7, xiv. et t. xvi, 1st part), recording their experiments in pathology, have shown very strikingly the important rôle this nerve plays in increasing intra-ocular tension. It was highly probable, then, in the author's opinion, that this case was one of glaucoma, the result of neural- gia of the 5th pair. - It was difficult to say what had caused the loss of the right eye, possibly glaucoma fulminans. Most of the teeth had been extracted, and pressure on those that remained did not increase the pains. On touching the skin of the brow, of the cheek, of the MAR. 28, 1872.] TIEEE C T.I. NI c. 139 ear, or of the inferior maxilla the patient experienced nothing in particular, but when that of the upper lip and of the angle of the nose on the left side was touched the cries were increased, the muscles were violently contracted and the pain so severe the patient could scarcely endure the touch. The slightest touching with the finger at these points sufficed to produce the most | cruel attack. - - - We have in these spots a perfect representation of Brown-Sequard's epileptogenous zones. [We refer the reader to Professor Brown-Sequard's lecture before the Academy of Medicine as published in the last number of THE CLINIC on these zones]. It is well known that cases analogous to those artificially produced exist in man. Violent general convulsions and veritable epileptic attacks occurr as | medical and surgical treatment. the result of a peripheric irritation of a small portion of the skin often quite remote from the cerebro-spinal axis. . . - A similar order of things occurs in those cases of irritation of the mucous membrane of the bowels, for example, by ascarides and other worms, in children, followed by general convulsions. - This case without doubt must be regarded as of the same class, and if the deductions are correct and the point of departure of the disease is from this morbid zone, operating upon it would produce a satisfactory therapeutic result. * . - A division of the infra-orbital nerve was made. Immediate complete anesthesia followed in the region where such intense pain had just been experienced, and | the patient was entirely relieved. No return after four months and a half, the time of writing. - The author proposes to collect and publish the cases already recorded, which he thinks admit of a similar interpretation. - Conclusions. The following conclusions are arrived at from this C2SO - - 1. Irritation of the trigeminus can produce glaucoma, as other clinical observations and the physiological ex- periments of Hippel and Grünhagen have demonstrated. 2. There exists a form of facial neuralgia of serious import from the intensity of the pains, their frequent appearance and their long continuance, accompanied by local and sometimes general muscular contractions. whose starting point is peripheric and confined to a small zone upon the skin. 3. This form of facial neuralgia presents itself with an assemblage of symptoms altogether similar to those attributed by authors to the classic disease known as epileptiform or convulsive facial neuralgia, tic douloureux of the face, etc., whose origin, instead o being peripheric, is probably central. - 4. Probably the two diseases presenting the same symptoms have been confounded, as the attention of observers had not as yet been called to these painful ZOI) eS. - - . - . In the author's case, for example, several physicians had already diagnosed the classic disease, so rebellious to all medical and surgical treatment, and had therefore been unable to render the patient any material aid. 5. To differentiate this new form from the old, I will designate it as convulsive neuralgia with peripheric zone, not using the word epileptogenous zone inasmuch as the attacks are never accompanied by loss of consciousness consequently not by the characteristic mark of epilepsy. 6. Convulsive neuralgia with peripheric zone may be completely cured if the zone can be found, either by dividing the nerves that pass to it, or perhaps by other Iſle?AIlS. The central form, on the contrary, resists as a rule all VESICO-URETHRAL ABSORPTION.—A number of ex- periments have been recently performed by Dr. Edward Alling which prove absorption by the mucous membrane of the urethra. The mucous membrane of the bladder in health absorbs almost nothing but in disease its ab- sorptive powers are very much increased. Opiates particularly were readily absorbed by the inflamed membrane of the bladder.—Gaz. Med. de Paris, Feb. 3, '72. —sº-º-º- On the Aspects of Law and Medicine in Relation to our Criminal Jurisprudence, with Special Reference to Cases of Insanity. BY DR. GEORGE MAY, President of the Reading Pathological Society, Public attention has been drawn to this important subject by the late trials of the Rev. John Selby Watson and Christiana Edmunds, the results of which I cannot but regard as a reproach to our legislation, too intol- erable to be longersustained. The only plea of insanity accepted by the judges in criminal cases, is the inability of the prisoner to distinguish right from wrong at the time when the crime was committed. The opinions of many learned psychologists are in direct antagonism to this legal dictum; and they declare it to be erroneous and inconsistent with our knowledge of the manifesta- tions of unsound mind. This conflict of opinion has been so painfully developed in the trial, conviction, and subsequent reprieve, of Miss Edmunds, that public feel- ing has been shocked, and our laws have been brought into general disrespect if not contempt. It is believed that many persons of unsound mind retain the abstract knowledge of right and wrong, although the judgment and power of controlling the will may be diminished or perverted, though not entirely lost. If this be true, it 140 [MAR. 23, 1872. TiEEE ci. ITTI c. must result that every alleged criminal act should be held responsible to the law; extenuating circumstances being admitted under the plea of insanity, and punish- ment awarded according to the degree of proved mental aberration. To admit the contrary, would be a direct encouragement to crime and dangerous to the public weal. Both law and medicine are concerned in the solution of this important problem. Law deals with the applicability of the penal statutes; and medicine, per- sonified in the experienced physician, must be the best exponent of psychological phenomena, since the struc- tures and functions of man, and the physical and mental derangements to which he is subject, are the objects of the study and practice of his professional life. When skilled in forensic investigations, who can be found bet- ter qualified to detect the crafty malingerer and to elucidate the truth? Now proving the offense to be the act of an unfortunate aberrant, and now only the cul- minating crime of a life of hardened villany. But to give due weight to the judgment of such a man, he must take an official position in the judicial inquiry. Trial by jury, so dearly cherished by Englishmen as the palladium of our civil rights, is sorely taxed in cases of disputed insanity. If to define sanity and insanity be a puzzle to the most acute metaphysician; if to fix the boundary in many cases be simply impossible, is it rea- sonable to expect a jury composed of men of ordinary intelligence satisfactorily to dispose of cases involving subtle distinctions, and replete with doubts and diffi- culties even to the most accomplished medical jurist 2 We need not wonder that medical evidence is not always complimentary to our profession, since all legally qualified practitioners are not psychological experts, and from the nature of their professional engagements and the absence of special training they cannot be; and yet they are called to give evidence and to express opinions for the guidance of juries on the issue of which hang life or death. At the trial of Miss Edmunds, important medical evi- dence in favor of her insanity was adducted; but it was overruled, the unhappy prisoner was convicted and condemned, and then submitted again to medical inquiry and ultimately reprived. Surely this reproach to our jurisprudence cannot endure. I venture to ask the members of this society to concur with me in assert- ing the time to have arrived when in the name of justice and humanity, and for the honor and dignity of our profession, we are called to urge the legislature to inves- tigate and revise our laws in relation to criminal juris- prudence, and , specially with regard to cases of questionable sanity.—Brit. Med. Journ, Mar. 2, 72. SYPHILIS IN THE APE.--Dr. Schmidt reports in his zoological clinic that, according to a communication from Edward Lund in Manchester, an ape had his penis almost entirely destroyed by ulceration, that the hair fell out in places and that the frontal bone as well as some of the long bones were perfectly carious. In the zoological garden of Bellevue at Manchester where the animal died it was ascertained from the keeper who had had charge of the apes for a number of years that these animals had been previously subjects of a disease which was characterized by ulceration of the external organs of generation and which was extended by sexual intercourse. In the same collection in which the ape had lived there was a female ape diseased in like manner; the vulva was surrounded by condylomatous formations of considerable size and there was an abund- ant sero-purulent vaginal discharge.—Schmidt's Jahrb., Feb. 14, '72. - —-nº-O-ºsm-- or the Probabie Action of Alcohol in the Body. BY DR. LIONEL S. BEALE, F. R. S. But we may now very briefly consider the influence of alcohol upon the organism, and its probable operation as an article of diet. What becomes of alcohol when it is" taken into the stomach 7 There is no doubt that if the spirit is strong when introduced, it is much diluted by the pouring out of fluid from the vessels and glands of the stomach, and that it is quickly absorbed, in its diluted state, into the blood. That this is so is proved by the familiar fact that the smell of alcohol is often very perceptible in the breath. Moreover, as is well known, alcohol has been detected by chemical tests in the breath, in the sweat, in the urine, and in the other secretions by a number of observers. Alcohol has also been proved to exist in the blood. There is, therefore, no doubt that alcohol, as alcohol, may not only be taken up by the blood, but may circulate with the nutrient fluid, and eventually pass away from it un- changed. But it must not therefore be concluded that all the alcohol every person takes is thus absorbed as alcohol, caused to circulate through the body as alcohol, and at last excreted unchanged; for such a conclusion would be opposed to the facts of observation and ex- periment. The truth seems to be, that some of the alcohol taken, is unchanged in the system, but that a considerable and very varying proportion of the total quantity introduced is caused to disappear altogether as alcohol, and to pass through most important changes, escaping at last from the organism probably as carbonic acid and water. - A certain quantity of alcohol is digested and assimi- lated; and it is quite certain that the capacity for the digestion of alcohol varies very remarkably in different individuals. It is most probable that the alcohol is taken up by, and carried with, the portal blood to the liver. It is then appropriated with other substances by the bioplasm of the hepatic cells, and completely changed. Its elements are arranged, and added to the constituents which form the liver-cell, and which grad- ually break up to form the ingredients of bile, the liver-sugar, and the so-called amyloid matter. MAR 28, 1872] TIH. H. C. T.I. NTT c. 141 . . It is the living matter of the yeast-cell that splits up to form alcohol and carbonic acid, water, and a form of cellulose. We shall not be surprised to find that another form of living matter—that of the liver-cell—has the power of appropriating alcohol, rearranging its elements, and causing them to combine with other elements to form compounds having properties very different from those of the materials out of which they were made. And it seems probable that under certain circumstances other forms of bioplasm of the body are able to take up and appropriate alcohol; for it is certain that in some prolonged cases of exhausting disease a large amount of alcohol is readily assimilated, while ordinary foods can only be taken in such infinitesimal amount that we cannot attribute to them much influence in the main-l tenance of life. In severe cases of fever, as I shall again have occasion to state, the greater portion of the alcohol introduced is probably not oxidised, as used to be supposed, but appropriated. Its effect is to lower, not to elevate, the temperature ; and, so far from in- creasing the dyspnoea in bad cases of bronchitis, pneu- monia, etc., by throwing increased work upon the lungs, as used to be affirmed, it has a directly contrary effect. Dr. Parkes has shown that diluted alcohol, given daily in such proportions that not more than two ounces of absolute alcohol are consumed in the twenty-four hours, in most cases improves the appetite, and slightly quickens the heart's action; but that larger amounts have an opposite effect as regards the appetite, and greatly increase the cardiac beats. Anstie and Dupré showed that if doses of alcohol sufficiently large to produce narcotic effects are taken, alcohol escapes in the excretions, but when smaller quantities are taken, alcohol escapes in the excretions, but when smaller quantities are taken it is not to be detected. This may be the true explanation of the fact that alcohol in certain cases cannot be detected in any of the secretions at all. It is certain that the quantity required to produce narcosis varies greatly in different individuals, and perhaps this may account for the different results obtained in the course of different experiments: Dr. Dupré has quite recently proved that, of the alcohol taken in moderate doses (48 to 68 grammes of absolute alcohol), only a minute fraction is excreted as alcohol, while by far the larger proportion is disposed of in the system in some other manner.” Dupré's obser- vations show that this alcohol is not stored up in the system as alcohol, and slowly evolved in the form of alcohol. He remarks that the amount of alcohol eliminated per day does not increase with the continu- ance of the alcohol diet, and that, therefore, all the alcohol taken daily must be disposed of daily, and con- verted into some other substance in the system.f * Proceedings of the Royal Society, January 25, 1872. f Dr. Dupré has discovered in the urine and in the breath a substance, which, though not alcohol, gives the ordinary reactions relied upon for detecting that substance. It yields acetic acid by oxidation, and gives the emerald-green reaction with bichromate of potassium and strong sulphdric acid. It yields iodoform. This body was found after Bix weeks’ total abstinence from alcohol, and was detected in the case. of a teetotaler. We must therefore conclude that, of the alcohol taken, only a small but very variable amount is ex- creted as alcohol, but that the larger proportion, at least in the case of most organisms, is changed in the system; not simply acted upon by other things in a state of change, as may be effected out of the body, but actually taken up by the living matter or bioplasm, appropriated and converted into other substances. Though probably not applied to the nutrition of tissues, its elements may perhaps assist to form some of the con- stituents of bile, sugar, fatty and amyloid matter.— Times and Gaz., Mar. 2, '72. - —sº-º-º- MEDICAL NEWS A GENEROUs TESTATRICE.-Madame Reid, according to the London Times, has left £110,000 sterling to the consumption hospital at Brompton. PATRIOTIC.—The society of Medicine of Paris unani- mously voted to transfer the fund for the annual ban- quet to the national subscription for the ransom of France. BABY FARMS.—The existence of a “baby farm” was discovered a few days ago in Marseilles by a novel species of detective. A mastiff was seen carrying the arm of a newly born infant in his mouth, and his move- ments being watched, led to the arrest of a woman who confesses to have exercised this calling for thirty years. THE LARGEST ConsulTING PRACTICE IN THE WoRLD.—Dr. Gull, of Guy,s Hospital, London, is said to have the largest consulting practice of any physician in the world— worth not less than £25,000 a year ($125,000). ANECDOTE OF DuPUYTREN.—The large class of re- calcitrant patients Dupuytren used to circumvent by means of a bell. When a patient who ought to pay left his consulting room without bestowing the customary honorarium, he touched a particular bell, whereupon the porter, before opening the front door, said: “I believe monsieur has forgotten his fee,” and thus forced the would-be-dead-head to be honest. - AN EPIDEMIC OF ICTERUS.—During the past three months Paris and all its environs have been subjected to an epidemic of icterus. CHOLERA.—Cholera has completely disappeared from Constantinople. The officer of health has removed all naval restrictions since Jan. 22. TEACHING AND PRACTISING.—There is a law in Bel- gium which prevents professors in the University of the state from exercising any other avocation, without special permit from the government, than that of in- struction. The minister of the interior Kervyn de Letterhone has recently called the attention of the pro- fessors of medicine to the fact that they are also subject 142 [MAR. 23, 1872. TEEE CI.I.INI c. to this law. It is the intention of the government to grant the privilege of practice in only the most excep- tional cases. This law, comments the Paris Gazette, is exceedingly wise. Professors of a state institution should devote their whole time in their didactic lectures to the theory and in their clinical to the practice of medicine. In France everywhere position is aspired after as a means of obtaining a clientèle which, when obtained is alike | injurious to the education of students and to the pro- gress of science which the professor has no longer time to cultivate. This subject should meet with our [France] most serious consideration in the reorganization of our system of medical instruction. It is, however, no more than just that if our professors are to be deprived of the rev- enue, often very lucrative, attending a large clientèle, the state should assure them a large and fixed compensation, at least should grant them the income from the inscrip- tions of students attending their own lectures. —º-e—sº- CORRES) PONIDENCE. CHILLICOTHE, O., March 11th, 1872. EDS. CLINIC; Last fall I was sued for mal-practice—in a case of oblique fracture of the femur at the junction of the middle third. The trial took place a few days since, lasting 7 days. I was honorably aquitted of all charges. Enclosed you will please find a synopsis of the judge's charge to the jury. The profession is deeply interested in all such trials, hence I forward you the enclosed for publication. Another physician has been sued for mal-practice in a similar case. The trial will take place in a few weeks. Yours very truly. B. F. Miesse, M. D. synopsis of the Charge to the Jury by Judge Samuel F. Steel. J. W. Marys, Plaintiff. 2)S. Benj. F. Miesse, M. D., Defendant. In order to entitle plaintiff to recover in this action he must satisfy the jury by a preponderance of the evi- | ence: first, that defendant attended him in the char- acter of a surgeon and undertook to treat his fractured thigh. It is immaterial whether he was employed by the plaintiff or by the township trustees; his liability would be the same in both cases. Second, that from a want of ordinary skill on the part of the defendant, or a failure on his part to exercise ordinary care in the man- ner of treating the plaintiff, the latter has been injured; that is, that the leg is shorter or weaker than it would have been if treated with such skill and care or that the plaintiff was put to greater inconvenience or suffering by reason of such want or failure on the part of the defendant. What is meant by ordinary skill and ordinary care is that reasonable degree of skill and care which is ordinarily possessed and exercised by men who practice the profession of surgeon and hold themselves out to the public as qualified to practice that profession. If the jury find from a preponderance of the evidence, that in treating plaintiff's fractured thigh the defendant did not exercise ordinary skill or care and that the plaintiff was injured thereby, your duty will then be to - determine the amount of damages the plaintiff ought to recover. In estimating these you have the right to take into consideration the plaintiff’s loss of time, his pain and suffering, and expense occasioned by defendant’s want of skill or care, and such injury to him and to his business, as will in future probably result from the injury he has received by reason of the defendant's negligence, and to give the plaintiff such damages as will compen- sate him for all these things. And if you should find that the defendant was guilty of such gross negligence as to show wantoness or to indicate intentional wrong on his part, you may go beyond the rule of compensa- tion and allow such damage as you may think proper by way of punishment to the defendant. But the law does not presume either a want of care or a want of skill on the part of the defendant. One or both of these must be made out by the plaintiff. It is not for the defendant to prove his innocence but for the plaintiff to prove defendant's guilt. In the absence of an express agree- |ment to that effect the law does not imply an agreement on the part of the surgeon to effect a cure, but it does imply an agreement on his part to treat every case he undertakes with ordinary skill and care, and that in cases of doubt as to the best mode of treatment he will use his best judgment in the matter. —º-o-º- OPPOSITE YALE COLLEGE. NEW HAVEN, CONN., Mar. 16th, 1872. EDs. CLINIC: Dear Sirs:—We mail you this day a copy of the “College Courant” published by us. We de- sire to obtain in every college one or two persons who, during the year, shall send us items of news or articles. We would propose to send you the paper for one year for $2.00, one-half the subscription price, provided you will occasionally send us an item of news from your college. - Very Truly Yours, . Chas. C. Chatfield & Co. MEDICAL COLLEGE OF OHIO, F. CINCINNAT1, OHIo, Mar. 20th, 1872. EDS :- CoLLEGE COURANT: Dear Sirs:—We mail you this day a copy of “THE CLINIC” published by us. MAR. 23, 1872.] TIH. H. cIIISTI c. 143 We desire to obtain in every college one or two persons to become subscribers. We would propose to send you “THE CLINIC” for one year for $2.00, the regular sub- scription price, provided you forward the item of expense. Very Truly Yours, PUBLISHERS CLINIC. —-tº-e-ºº----- C. LINEICAI, MEMORANIDA, Chloral, Clinical and Experimental Researches. BY DR. ZUBER, (Strasbourg). Chloral was presented to materia medica by Drs. Otto and Liebreich in 1860 before the Faculty of Med- icine at Berlin. It was discovered in 1832 by M. Liebig as the result of the long continued action of chlorine upon alcohol. The liquid chloral mixed with a little water combines with it and presents then in the form of a crystalline mass non-transparent, the hydrate of chloral : C2 C13 k }co, no 2HO. H It is the hydrate of chloral that is employed in therapy. - In his most excellent work M. Zuber remarks tha when it is given in small doses frequently repeated it produces no good effect, as the action of the first dose is lost before the remedy is repeated. It must be given them in one dose. – It is administered by the mouth, in applications and in subcutaneous injections. M. Zuber recommends the dose as follows: For infants - - - - - 2-3 gr. 4-5 gr. 5 gr. and over. For women gº º tº EE tº For men - - • - - - The ordinary formula is as follows: R. - Chloral hydrat. 4-6 gr. Syrup Syrup. Aurant, aa 15-20 gr. -º- If only a light sedative action is desired, it is obtained by the formula of Liebreich . - B. Chloral hydrat, 2 gr. Mucilaginis 15 gr. Syrup 30 gr. Aquae dist. ‘S. Spoonful doses every half hour. The application of chloral should be concentrated. It is not an advantageous method of administration. |utes to the development of normal tissue. In subcutaneous injection its absorption is easily effected. This method, however, is liable to local accidents, M. Zuber has had one abscess result, one eschar. M. Liebreich has never observed an accident. M. Zuber terminates his work with the following con- | clusions: 1. Chloral hydrate, pure and in sufficient dose is a powerful sedative to the nervous system. 2. As a hypnotic it induces sleep rapid, profound, rarely preceded by a period of agitation and followed by no malaise; a sleep preferable to that of opium. As an anaesthetic it produces a light diminution of sensibility, sufficient to permit explorations and minor |operations; but it cannot substitute chloroform in the great operations of surgery.—Gaz Med. de Paris, Feb. 10, '72. ARSENIATE OF QUINLA IN TETANUS.—Dr. Pietro Galli has employed this remedy in tetanus with most ex- cellent results. It acts in two ways, against the nervous element of the disease and against its intermittency. This first action is secured by the arsenic, a reliable anti- periodic and at the same time sedative in relieving the partial alterations of the nerves; the second action is secured by the quinia, a remedy whose sovereign power in this direction is universally known. These two rem- edies thus simultaneously employed and reinforced also by opium to relieve the activity of the circulation and facilitate absorption contributed much to the recovery of the cases mentioned. The malady presented the characters of a veritable intermittent fever accompanied by tetanic pains. As it has its seat in the central por- tion of the central hemispheres extending out along the ramifications of the trigeminal nerve and involving the spinal cord with the connections of the great sympa- thetic, it demands a medication of such heroic action as to combat at the same time its periodicity and the grava concomitant symptoms.-L'Ippocratico–Gaz Med. d. Paris, Jan. 29, '72. A QUININE COLLYRIUM.–Dr. Vincenze Gotti lauds the value of a solution of quinine as a collyrium accord- ing to the method of Magni in his clinic at Bologna and urgesstrongly its adoption in the therapy of ophthalmolgy It has been recommended some time ago by Prof. Nagel of Tübingen. It is to be used especially in cases of kerato-conjunctivitis scrofulosa. It acts further—as the four cases would seem to prove—in a most surprising way in phlegmonous affections of the cornea and in corneal wlceration, as it checks the formation of pus and contrib- The quantity used is 0. 25 [3. 3-4ths gr.] to 30 [450 gr.] distilled water. The application which is not painful should be made several times a day.—Riv. clin. iv. io, cii.- Schmidts Jahrbücher, Feb. 14, '72. PoſsONING BY ATROPIA.—What then in conclusion | are the different means of therapy from time to time introduced in cases of atropine poisoning. The first indication consists, if the poison have been 144 [MAR. 23, 1872, TIH. H. CLINI c. ingested per stoma, in recourse to evacuants; emetics and purgatives may in some cases remedy the dangers and hasten the cessation of the toxic effects. With a view of neutralising the action of the atropine certain pharmaceutic preparations have been employed from time to time, with greater or less success, as iodine, io- dised water, iodide of potassium, tannin, caffein, thein, etc. These various substances in combining with atro- pia form insoluble compounds. Of all the various medical agents opium is the remedy, without doubt, which has played the chief role in therapy in recent times. The fact of the myotic action of this substance in contrast with the midriatic of atropine led at once to the view of its specific antidotal power. 3. This antagonism recognised between these two agents, however, has been contested by most authors. For our own part, notwithstanding the fact of its employment in our case, we do not believe opium to be possessed of the antidotal powers imputed to it, being persuaded that most cases of atropine poisoning terminate favorably spontaneously.—Prunac—Gazette des Hospitawa, Jan. 27, 72. —-º-º-º- On the Treatment of Pleuritis. BY DR. H. QUINCKE. Private Docent in Bærlin. The following are the eonclusions from an extensive and most interesting article in the last number (Feb. 19, 1872), of the Berlin Klinische Wochenschrift: The best method of removing serous exudations is by ouncture with a small trocar and suction. Except in cases in danger of apnoea the puncture is to be undertaken in large as well as in small exudations as soon as absorption is in any way delayed. Even in those cases where a palliative effect only is to be hoped for, puncture is still often indicated. in purulent, exudations incision, and subsequent cleansing out of the pleural cavity with fluid and air is to be undertaken on all occasions and early for the the reason that spontaneous absorption is improbable in these cases, certainly is very tedious. In many cases of pneumothorax also where purulent exudation has taken place operative treatment is in- dicated. º ——º-e-ºs- | HOM IE NEWS. THE SPRING CourSE opens with thirty students, nearly double the number of this time last year. Full particulars of the course with other matters of interest to the student, will be found in the student's supple- ment to be had in the college library. PROF. BRown-SíquaRD still remains in our city. It is rumored that he will permanently locate in either New York or Cincinnati. WE HOPE TO BE ABLE to make such arrangements with the Secretary of the Academy of Medicine as to secure us a weekly abstract of its proceedings. Medical College of Ohio. S P R | N G C 0 U R S E , The regular eight weeks course of practical instruc- tion for the Spring of 1872 commenced March 15. Un- usual advantages are offered this year in the fact that the course will be conducted by the entire Faculty of the College. - The course embraces the following topics: Clinical Medicine—Bartholow. “ Surgery—Dawson. Anatomy Brain and Nervous System—Gobrecht. Operative Surgery—Conner. {{ Obstetrics—Reamy. {{ Ophthalmology—Seely. Female Pelvic Surgery—Palmer. Urinalysis—Nickles. Physical Diagnosis—Cleveland. Fractures and Dislocations—Kearns. Genito-Urin. Dis.—Anderson. Microscropy—Whittaker. Prof. Graham will deliver occasional lectures on Clin- ical Medicine and Diseases of the Chest during the pro gress of the Course. The design of the Course is to present instruction in a thoroughly practical manner. Physical Diagnosis is to be demonstrated in the hospital wards; Operative Surgery, Operative Obstetrics, Operative Ophthalmology, and Operative Gynaecology on the cadaver. The Dissecting Room will be under the supervision of Dr. Brown, where abundarit material will be provided. Special attention will be paid to the chemical and mi- croscopical analysis of morbid urine. In order to render this course the most practical pos- sible, an opportunity will be afforded each individual of the class to make the various examinations and opera- tions on the living and dead subjects. Regular daily Medical and Surgical Clinics will be held at the Good Samaritan Hospital: Two Daily Clinics will be regularly held in the Cincinnati Hospital, throughout the entire course; and a Daily Clinic will be held at the Dispensary of the Medical College of Ohio. One hour each evening will be devoted to Recitations on Anatomy, Physiology, Practice, Surgery, Obstetrics, and Materia Medica. - The eminently practical nature of this course, and its shortness of duration, together with the great clinical advantages presented in Cincinnati, can but commend themselves favorably to the practitioner as well as the student. • * - - FEES FOR THE ENTIRE Course, $10 As this Course does not count towards graduation, being considered supplemental to the regular winter course, graduates of the College are not required to matriculate. The matriculation of non-graduates is deducted from the fees of the ensuing winter session. DIVIDED MEDICINES, The Divided Medicine Com’y, CINCINNAT1, OHIO. The Company have the honor of bringing to the notice of the Profession, this NEw AND ExcEEDINGLY PRACTICAL METHOD of dividing into doses. Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. The Divided Medicines are prepared by FREDERICK KRAUs, Chemist of the Company, with the most scrupulous" accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a mannér that the several squarEs must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MoRE. .. - - -- The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every square will consequently contain accurately measured quantities. - But not only SolubLſſ, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINES. - - - This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, ; : # *. iło, and even idbo part £f a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. - - - - - Besides the peculiarity of THESE MEDIGINES, that they are NOT LIABLE To SPOIL BY ANY LENGTH of TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calis with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares) within four days. For Saxmpies, Price Lists, and Agencies, address w EOIX. 2688, Or FRFDERICK KRAUS, Chemist and Druggist, - Walnut Hills, Cincinnati, O. MR. FREDERICK KRAUs: CINCINNAT1, February 15, 1871. - - Dear Sir—The specimens of your “ Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: - SULPII:MI0 RPH II....................... % grain in each square. ARSEN: ACID.......................... 1-20 grain in each square. “ CH IN.INI ....................... 1 as “ . “ CALOMEL % “ s * I tº º COPPER ...“º § { - ResPECTFULLY Yourts, E. s. Waxse, Analytic Chemist ||||||||}|| MM|| ||M|| Fos"TER’s ~. 167 EAST, 34TH-St., NEW YORK, By Special Appointment Electrical Instrument Makers to the New York State Hospital for Nervous Diseases, MANUFACTURERS OF PORTABLE ELECTRO-MAGNETIC MACHINES, Portable Galwanic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, 1870, and May 30th, 1871. These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery Fluid. - |M|| ||||—||f|| || PEERMANIENT BATTERIEs, For Hospitals and General Practitioners, IEET ITECTIER, OTDIES. For Eye, Ear, Larynx, Nose, Uterus, Wagina, Bladder, Rec- tum, Feet, Phrenic and Sympathetic Nerves, Elec. trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. FºxTRA tºt'S FRONT TH F O PINIONS OF THE WroST JEMI NENT MEMBERS OF TLRI; PIE OFESS / ON. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “Nothing CAN EXCEED THE EFFICIENCY AND CONVENIENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” We are authorized by Prof. Hammond to announce en- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- proved and re-modified Instruments made by our Company. A MEREDITH CLYMER, M. D., Prof. of Diseases of the Neº- vous System and of the Mind, &c., &c.—“I consider their Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” - LEWIS BAUER, Prof. of Surgery, St. Louis : —“In neat- ness, compactness and efficacy, they can not be excelled.” ALFRED C. G ARRATT, M. D., Boston :-"In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” * -> Similar Testimonials have been received from JOHN J. CRANE, M. D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A. MUR RAY, M. D.; CHAS. E. BLUMENTHAL, M. D.; E. C. SEGUIN, MI. D.; ALLEN MAYNARD, M. D., Cleveland, O.; Dr. C. WANNIE, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES KELLY, Florence, 0.; Dr. JOHN BECKER, Brighton, Iown; Dr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes- barre, Pa.; JOHN J. CALDWELL, M. D., Brooklyn, and many other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an • Electrical Instruinent for medical purposes. CALL OR SEND FOR CIRCULAR AND PRICE LIST. \\limlija –28, LIMIB5 \\ =<-2 W Are furnished to Officers and Soldiers on Government account. I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb – why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb. etc., etc. All communications should be addressed to -JAMES A. FOSTEE, 911 º'hestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cinginnati, Ohio, or 172 Jef- ferson Avenue, Detroit, Mich. SAML. P. THOMAS DEA LEF IN English, French and Scotch GOOD's, 34 West Fourth Street, & Z-W'6'' A.W.W.?? We - *- _-_----- a- * = ------ -º- *-*- as - *-*-*-sº-sº *-*- - - -º-º-º-º-º-º-º-º-º-º-ºs- -*-r -º-º-º-º- *-*- º * - * , sº wº- - - -*-* *-*-* -- - *- ------- - • *-*-* *- -º-º-º-º-º- --- **-* **-m- -*-*--- – :---- *F-F- *-** -º-º-º-º-º-º-º-º-º- * ---------- -* - - * * **** <--—- * *-*-*-*-** **-**-*- *-m- *-*-*-* --- -º-º-º-º-º- -º-º-º- -º-º-º-º: *- <= -==== sº-, -ss- - -º-º-º-º-º: -ms. −” -- ---" =--------------- - - -*-*. -º-º-º- - - i. **-*-*. * * -º-º-º-º-mm-mm-mm-mm- *-*-** * ...t. -- —-º-FE --> § <-- - ET - sº- *-*-*-*-m-mºss-sº-º-em-sºmeºn-mº-nº-ºº- =-º-º-º-º-º-mee-mºr -- *-*-*-m-º-º-º-º-º-º- *--------- †: :==E ºfte-F Eº-E - *-m-s-s-s-sm - ~~~~~~ ºz --------------- -*-* --~~-- +EET">E 33%- • *--ºr wºm-m-m- *-*-*-*-*-*-*-*. F-ºº::=~ *-E. F- ------s - *::= Zºe *-* *-*-em- - ------- - ºf- - "T----- - *-*-ºs- -as- cº- * * *-*-*-*-m-tº-sº- -ms--- - ºt: - *-* *-*-m-m-m- -- *-m-s- º --- * ---m- * - A sº º -- -*-m-m-m-m-m- * - -*. tº * =-- *T --> -- - - - - - ** A. -- - - - --------. **-* º mº- - - - 7- - sº-ºs - -** * *-i- - - -**- • * **, - *-* —-T - * -*- *-*- *-* - --- *-- *-* - - *-m- - -º- # †- -: -- º | f jś w # | #| i i :*Aſ t - |. *, º tjø. §§§ º | # ill |# º º º: : iii; ES ######. º º º # l |# *... • * º ji #º § º gºšiº º Sºº §§ # # º º ãº:3#= º غ º-s, ś * → E:- E. º: - § º sis w Gº •- º - º:#: ź - &###: : ź Sººfiº tº §º -2&ºº. %:- ºº::#####$3% : a tº sº º/2- ######## º %: $252; ####### $º * º: - #ſº ºrate º P--- #3 Nº. !? 52:- - zºº ºftº -º º .* -º-º-º: Sºś Złżº - Sºś2%% §5:.S.- §§º 3.3% §% º 3% §§3% %2% #===ºs;=& %%zº - --~~ - E: ESESºcº sº Ż zze--- GOOD sAMARITAN HOSPITAL. The GooD SAMARITAN HOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner It is handsomely furnished throughout, and is provided with all the necessary ap- Porticoes, with commanding views, surround the whole house, and wide ial to health and comfort. of Sixth and Lock streets. pointments of a First-class Hospital. halls and abundant windows secure that full and free ventilation which is so essent Service is furnished by the SISTERS OF CHARITY, Under the Superintendence of the well-known SISTER ANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. The regular Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each Professor presiding over his own especial department. Patients may, however, select from the regular profession of the city any physician of their choice. The GOOD SAMARITAN HOSPITAL presents extra inducements to Invalids throughout the State as a safe and quiet asylum in any case of protracted illness, or in cases, more particularly, requiring Surgical Operation, where some stay is necessary in after treatment. wº Rooms vary in price, according to the character of appointments necessary and service required, ranging, jº general terms, between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand ot service. tº Address, SISTEER ANTHONY, Hospital of the Good Samaritan, Corner of Stacth and Lock Sts., Cimoirºmatº. Ohio- WILSON BRO's. R P3. T VVA. IN'S MA $ S HIRTS Made to order of N. Y. M. Muslin and 2300 HEAVY Linen, per dozen - - - $26 00 Wamsutta Muslin and 2100 IIEAVY Lin- en, per dozen - - - - - - - - 33 00 Wamsutta Muslin and 1900 Linen, per doz. 30.00 Lonsdale Muslin and 1700 Linen, per doz. 27.0). First three qualities have ALL LIN EN Cuffs and Neckbands. At above prices Cuffs are attached. Same quality of our own manufac- ture, ready-made, $3 per dozen less. Perfect satisfaction given or money cheerfully refunded. Also import and Manufacture Men’s Furnish- ing Goods. Pike's Opern-House, Fourth Street, Cincinnati; 931 Wabash Avenue, and 88 West Washingtons - Street, Chicago. CAM ALI R.G.O MANUFACTURING COMPANY, MANUFACTUREIs AND IMpontens of A ND Window Shades, dº Wasr Fovara Srager, CINCINNXT, O, B. B. BBENEMAN, Proprietor, * - - NEW TE O O. Ex IS NOVV READY FOR CA NVASSERS. It contains over 600 pages of rending matter, with 250 engravings, designed txpressly for this work, by the best artists in the country. Agents now at work upon it are meeting with unparalleled success. Agents at Circleville, O., reports 25 orders in 2 days; one at Louisville, Ky., . reports 175 orders in 8 days; one at Middletown, Conn., reports 200 orders in 12 days; one at Cincinnati, O., re- ports 250 in 12 days. Early applicants secure choice of territory. For circulars, terms, &c., address NETTLETON & Co., 161 Eton Street, Cincinnati, O. -diº BASCOM & CARPENTER, Stationers, Printers Blank Book Manufacturers, 136 v1.NE sºrrºr:ET, &\\\\\\\\\\p E. D. ALBRO & BRO. IMPORTERS AND MANU FACTU it ERS OF FOREIGN and pºsticwoods In Veneers, Boards and Plank, frtiſii-Mºtº-Bilºuiii-Hinº, The only house in the western country that saws Spanish and Mexl: , can Cedar for cigar-Box Makers We import our own wood direct, and can sell at pric-s to compete with any and everybºdy. Also º keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. omee and warerooms, 136 and 138 West Second street, Veneer Mill, 507, 509, 5ii, 513 & 515 W. Sixth St., CINCINNATle * ** *- —-º * * * * *- - & e * * .4 • *s -- ~ * * * * * * * & *> 3. **, * © $ tº Yºº Y * º sº sº . 53. * *s } * .. .. f * * © . - \ \ 2 & i. JW2, 9% WESZ" A'alºzº, Szºzº, PIKE'S OFERA HOUSE BUILDING, In porter and Dealer Diamond and Gold Jewelry, Watches for Ladies and Gentlemen, Sterling Silver Tableware, Bronzes, Antique and Modern; Marble and Bronze Clocks, Marble Statuary, FAN cy. Coons, GENER ALLY. r ■ ■! ; : , , , ; , , , , , , , , :.: , , , , , , , , … +=:: * ,' * * * *, º* * ·* º *■ ' '; , , , , , , , ! !!!vº ! ' , ' ' ..., º +', ,'$% “?* , ! ·· · · · · * . ,|-* ... * *$ ſº 'º', ' ' + i * : ? ∞ •--·º ^ „ …ſº •∞ §•| ') +|-_2_(2)__) __,_,_Téſa · @ ₪) , , , , , , , , , … …….…) :# 21},...,', ,''' ([[№ſ ||,T}{{ſiſ}}%ſ*(?:(?:%(***)?). | + 1w , !ſººſ ~§..…., .º_º -Äſſä}}Lºs , , , , ,NS_2,…", $, ſăÑ . . . . .'), ! ¡ ¿• …º 2 < (~·№.5.• • • • • • • • •**■~~~~^^--.-.-.-.-.-.-.-.-…--·! ± 1. ^.^ſº ,ſaepºſ:5•~~·:•H|× ſº -!K(s) {-*, , , , , : · · · · · ·» . , º, , , : „ “!º º،º 11 || ► ►. . . . . . . '...º.. №ſſae' , :, ’:’, :’º.??? ..? - ?, ? - ?!∞ √° √ ( , , , , , , . }}sae ae …:…º aeſ ae• • • • •*.* ( , !ºſ ſae (NN)) + · · · · * * * *∞: , * * * * . ºae!= --!---,• • • • •ſ º∞-~ • • • • • • • • • º: º --> … . ". º, - - - - - Exº-º-º- ºr ===# - * sº-º-º-º- D - •-- ºv.º. º º : .* *- w - > º EE -ºt „…S#----§§ ~~~~--~~~::~~=+? ¡+! € ·ſae•.•º 8 .№ §§§f.? ©S,ſae! , , CINCINNATI. ~~~~~~~ ** F A c U L T Y S G R A H A M , Professor of the Theory and IPractice of Medicine and Clinical Medicine. D E A N , y M. D. J A M E W. W. DAWSON, M.D., Professor of Principles and Practice of Surgery and Clinical Surgery C. D. PALMER, M.D., Professor of Medical and Surgical Diseases of Women. T. A. REAMY, M.D., Professor of Obstetrics and Diseases of Children. •y M. D y Demonstrator of Anatomy. JOHN L. CLEVELAND CHARLES KEARNS, M. D •y A8sistant to the Chair of Surgery. •y ROBERTS BARTHOLOW, M. D Professor of Materia Medica and Therapeutics. W. H. GOBRECHT, M.D., Professor of Anatomy. P. S. CONNER, M.D., Professor of Surgical Anatomy. W. W. SEELY, M.D., Professor of Diseases of the Eye and Ear. EL NICKLES, M.D., SAMU Professor of Physics and Medical Chemistry PX E. F. , W H ITT A. ecretary of the Faculty. XVI E S T . of Physiology and S J. A. sys; O r" Profe ! Janitor Prosector of Anatomy. T. Louis BRown, College Building, Sixth St., bet. Vine and Race. Printed and Published by Norris & M URRY, Medical College of Ohio Building, Cincinnati. THE CLINIC. PUBLIsr ºf &RY sat URDAY. TEI, MS-82.00 a Year, Invariably in Advance. --> {: All Communications relating to Bus? . . ; ,&tions relating to Publications must be addressed to the Editer t § Jscriptions, Advertisements, etc., to the Treasurer. Vol. 2. C IN C IN N A TI, M A R C H 30, 1872. No. 13. -* JAS. T. whitra KER, M. - - - Editor. ºšš. ...i. co-Ary Le CCP t (...) W. W. D -A-SSO C.I.A ºn E :rriº . W. D.Awson, M. D. The Tâ. REAMy, M. D. ſº - P. S. ConneR, M. D. C. , i*ALMER, M. D. EC W. W. Seely, M. D. Y SAM fel, Nick'ss, M. D. Fashionable , atters, CHAs. KEARNs, M. D. { JN - L. CLE, LAND, M. D. IMPORTERS AND MANUFACTUREHS 0} RoBERTS £wthorow, M. D. - - r * - W. W. SEELY, M. D. wº f - - - - - TREAsukee. #Aº #ES.” FURS, No. 118 West Seventh Street, Cincinnati. y * T. clue ºaſes. 92 wrest E'OTTERTEL ST. — ``s , * Opposite Post Office, 4 Copies to one address...................................................... $ 7.00 : - 6 4 & 6 & - 10,00 3 CINCININATI. 12 4& “. ...... 18.00 sº special Inducements to Medical Men. a C O N T E N T S. * º ſ ſºlº Qº | ORIGINAL ARTICLES Bº *A ºlº º Tll. LM Amputation of the Cervix Uteri, by J. C. McMechan M. D.............. 145} 10)º ºbesic.N. ERS AND Cases Illustrative of Treatment by Air-Exhausting Apparatus by § \ || -º-º-º-º-º: . . . . WITF J. Bradley M. D. T45 $ENGRAVE RSonwoo D} TRANSLATE 6.N. -sºº B2 WEST fog/RTH Sºrrºr. | Digitalis, Its Action on Circulation and Temperature by Prof. S. CINCINNATI, OHIO, Ackerman (Berlin Klin. Wochensehr., Jan, 15, '72.)................... 146 r SCIENTIFIC NOTIES * * *-*-- J. TAFT, W. TAFT. Germs of Healthy Blood–Alcohol and Tobacco as Cause of Ambly- opia—How Brown-Séquard's Hair turned White....................... 147-148 Editor Dental Register M IELDICAL NEWS. International Medical Congress—Conquest of Alsace–Human Hair - J D & * W C TART N * * J º --ó- " —St. Paul and St. Luke—American Medical Association—Bogus Medical ºlig-bº of Dr. Foster of Lewisburg—The Syphilis Committee.................................................................. I-18-150 CORRESPONDENCE * IET: INTTT S T S Letter from Dr. Duncan—A Case in Teratology........................ ...... 150 - cLINICAL MEMORANDA • . . . ...º.º. 117 WEST FOURTH STREET, Spasm of Accomodation—Alcohol at Different Periods of Life....152-155 HOME NEWS. 155-156 * * * * * *-* = • *- *-*m- -y- ** ~y- WE have to-day a little high science in explanation CHIN (CIN IN ATI, O. of the action of digitalis on the circulation and temper- ature. It is to studies in this direction that we are in-f debted for whatever of positive knowledge we possess on ‘Rhe the action of medicines. ... $1. A rare case in teratology follows. |R. Mental º * \tº SSNs - egistero Our selections from ophthalmology are unusually A. Monthly J Ournal, abundant. This subject is being everywhere more rapidly developed than any other i. e. partment of CONTAINING 48 PAGES medicine. y We shall be able to present Prof. Bovºsaurº last lecture in full in the next Clinic. Devoted to the Interests of the Dental Profession, * * In calling the attention of Physicians and Druggists to the Cod, Liver). Oil manufactured by Messrs. MARVIN BROTHERs & BARTLETT, of Portsmouth, N. H., (of which we're the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. i * Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. ,” Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachitic Affections, in Chronic Rheumatism, &c. The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable iºthe stomach, but less valuable as a remedial agent. We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. List of Pharmaceutial Preparations, MANUEFACTURED BY Jozzy Wyżſzºg & Bºozºº, F.E.L.I.A.D.E.L.F.E.C.I.A. —º- ELIX, PHOS, IRON, QUININE AND STRYCHNIA, ELIXIR OF GENTIAN FERRATED, ELIXIR WALERIANATE OF AMMONIA, (Goddard's Formula,) ELIXIR VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, Iron, with Phosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Iron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK, ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER WINE OF IRON, Citrate of Iron and Peruviala Bark, FERRATED CORDIAL ELIXIR, ELIXIR CALISAYA BARK, WINE AND BISMUTH, ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, . FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, TASTELESS COD LIVER OIL, TASTELESS COD LIVER OIL. FERRATED, • BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and sherry wine, ELIXIRVALERIANATE OF STRYCHNIA, WINE OF PEPSIN SYRUP SUPERPHOSPHATE OF IRON, y ELIXIR OF BISMUTH, COMP. FLUIDEXT, BUCHU AND PAREIRABRAVA. STUI PIPOSITOTE&II ES. -- Bectum, Waginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great eare, and of every variety of combination. Lists sent on application. SPON GE TENTS.—For the Urethra, of every sise and style made of finest quality of spongº. William Autenrieth, ROBERT CLARKE & GD’S. No. 71 WEst, sIXTH st'REET, BKTWEEN WALWUT Añº VINE, CINCINNATi, OHIO, MANU FACTURER OF AND DEALER IN || || || ||||||||| Abdominal Supporters, Trusses, CLUB-F00T SHOES, SPINAL APPARATUS, ETſ reeps constantly on hand a full variety of Metalic and Rubber syringes, Storm.ach Punips, Etc. STOCKINGS FOR WAR}}COSE WEDNS, Epecial attention given to the fitting of Apparatus for Deformities. Bºy Agent for DR. L. A. BABCOCK'S Silver Uterine Supporter, —A LSO– DR. AHL's POROUS FELT SPLINTS, —ALSO – SIP T, IN T S -ANE)— D A. Y. *S , NICHOL’S FIRESIDE SCIENCE. LIST OF NEW Mill, iTH in Mºuli; inſ; GREEN'S PATHOLOGY AND MORBID ANATO MY, 8vo. Cloth. $2 5o * DUCHENNE'S LOCALIZED ELECTRIZATION. 8vo. $3 oo DILLENBERGER ON WOMEN AND CHILDREN’S DIS- EASES. 12mo, $1 75 BENNETT ON PULMonoRY consumption. 8vo. $1 go FIRST HELP IN ACCIDENTS. 12mo. $1 50 BEASLEY'S DRUGGIST RECEIPT BOOK. 8vo. $3 5o ECHEVERRIA ON EPILEPSY. 8vo. cloth. $5 oc HOWE ON EMERGENCIES. 8vo. $3 oo HAMMOND ON NERVOUS DISEASEs. 8vo. $5 od RINDFLEISCH'S PATHOLOGICAL HISTOLOGY. $6 oo WARINGS’ PRACTICAL THERAPEUTICS, 2nd Am. Ed. 8vo. Cloth. $5 oc Leather. $6 oo SCUDDER'S SPECIFIC MEDICATION. 12mo. Cloth. $2 5o TANNER'S HANDBOOK OF OBSTETRICS. 12mo. $2 oo VAN BUREN ON DISEASES OF THE RECTUM. 12mo. Cloth. $1 5o FLINT'S EXAMINATION OF URINE. 12mo. Cloth. $ 1 oo VOGEL ON DISEASES OF CHILDREN. 8vo. 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Instrument Makers and Practical Opticians, Beg leave to return thanks for the patronage extended to them through || a long series of years (having been established since 1836), and in the reorganization of their firm will endeavor to merit a continuation of the same. We wish it understood by the Profession and the Public generally that our invariable rule is, to make or import none but the best in- struments. Those in want of any of the acknowledged good aids of vision to imperfect eyes, will always find the best and largest stock of Lenses, Spectacles, and the best models procurable, with pains- taking skill to adjust them to all conditions of sight, at our house. Special attention paid to orders for Fine Microscopic Objects and Microscopic ſº Magnifiers and Readers in great variety. edical Batteries, Barometers, Thermo- meters, Hygrometers, Urimometers and ſtain Gauges, of the most approved construction always on hand. All orders promptly and accurately filled. º JAS, FOSTER, JR. e F. S. SHACKLEFORD, ! * * JAs. FostER, JR. & Co. J. S. W. Cor. Fifth & Race Sts., Cincinnati, 0. TXTER, S.INT. TMI. A_IF/STEL’S sº :- " R - y - w - :2 5KS:º º No. 758 BROADWAY, NEw Yohk I HAVE been in the habit of applying and recommending the Truss manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined. LEWIS A. SAYRE, M. D. Surgeon, Bellevue Hospital. Parker to S. D. Townsend, M. D., Surgeon to the Massachusetts General Hospital. BEG leave to state for the benefit of all concerned, Dr. S. N. Marsh the last fifteen years. * * * I am in the constant habit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with any of the risks to the patient that exist in many of the plans suggested and attempted to be carried into execution... I have confidence in Dr. Marsh as a gentleman of honor and integrity, and as such recommend him to the members of the medi- cal profession generally. WILLARD PARKER, M. D. - Professor of Surgery, New York City From Prof. Willard that I have known Br. S. N. Marsh's Patent Radical Cure Truss, and all other kinds of |. Trusses, Shoulder Braces, Supporters, Elastic Stockings, Suspensory | . Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Qure Truss Offices of S. N. MARSH & CO., No. 2 Wesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. oPPOSITE THE HIGH STEEPLE, R&^ Agents for Clement's Patent Artificial Legs, F. E. SUIR -. E. S. WAYNE suire & Co., WHOLESALE ORUGGDSTS, TM. A. IN TJ E A C T TJ IF, T INT GF £Hexists AND PHARMAceutists, CINCINNATI, OHIO. Have constantly on hand a full assortment of S}ex,)ecº)ex) ox{U GS ANYO IYXXE)0)(C)(NYCS, cºeroxcAx, Ax-eAHAºcus, TESTS, MEDICAL, GLASS WARE, &c., &o., r And solicits the patronage of the trade and profession- We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, & Made in accordance with the U. S. P. and other recognized authori- ties. FINE AND EAERHE CHEMICALs. Of the popular class of preparations known as IE T. T. DK I BR, S, We manufacture a full line. Those of our make may be relſed apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. Bitter Wine of Iron, An excellent Chalybeate and tonic, Wine of Iron, &c. AGENTS FOR BULLOCK & CRENSHAW'S Sugar-coated Pills and Granules. Price Lists of preparations and of Sugar-coated Pills sent by Mail upon application. The long standing and well and widely known repn- tation of our house we offer as a guarantee for the reliability of our preparation, and the quality of the goods sold by us generally. tº gº, ſº * º III, º WS- AFS: *---- *- . . ." ==Q º Užs) Carriage Manufacturer, NOS. 9 and 11 East Sixth Street, bet. Main & Sycamore. I MAKE NOTHING BUT F/APS-77 Czz SS. Wºo Ar A-, Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of g LIGHT FAMILY CARRIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive variety of light elegant designs of different cost and finish. In vehicles especially PHYSECHANS” {jSE, The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. - adapted to The superiority of my light gentlemen’s buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price lists furnished on application. References T TE-ITEH C T , T TNT I C . :*TY Vol. 2.) SAT U R DAY, M A R C H 30, 1872. [No. 13. O RIGINAL ARTICLEs. AMPUTATIon of THE CERVIx UTERI. - By * DR. J. C. McMECHAN, Cincinnati, 0. On October 8th, 1871, I saw Mrs. D.—for the first time. - - For eight years she had been suffering with an affec- tion of the womb. She was sterile and had dysmenor- rhea. She had been married nine years, and about one year after that event had had a miscarriage, self induced by the introduction of a knitting needle into the literus. On examination the cervix was found elongated at least an inch and a quarter. The neck was conoidal in shape. Intra-uterine measurement was three inches and a half. The uterus was retroflected. The next time I saw the patient, I called Dr. Whitta- ker in consultation, and we proposed to amputate the cervix. To this the patient consented, but on examin- ation the neck was found so congested and enlarged, (it was just after menstruation), that it was impossible to draw it down sufficiently close to the vulva to oper- ate. Another objection to the operation was that in the then congested state of the organ hemorrhage would probably have proved dangerous. It was considered best, as a temporary expedient, to open the neck by a bi-lateral incision. This operation Dr. Whittaker per- formed, and tents were introduced for several weeks to maintain the dilation so gained. On November the 13th, the patient not feeling sufficiently relieved, and there being no congestion of the cervix I determined to amputate. , Assisted by . Dr. Hancock, by means of the Sim's speculum and a tenaculum the neck was brought down to the vulva and amputated with the curved scissors. Nearly an inch of the cervix was taken off. But little hemorrhage followed, and the womb was kept well dilated for three weeks following the amputation by Sponge tents. . . . |Up to the time of removing the cervix the pain at each monthly period had been very intense for a number of years, so much so that the patient generally remained in bed during these periods. At the present time the retroflection has almost dis- appeared, having been treated simply by semi-weekly reposition with the sound for six weeks. Since the operation there has been no pain at the .145 menstrual epoch and the patient feels entirely relieved. She has never been pregnant since the miscarriage eight years ago, and could not possibly have become so owing to the mechanical impossibility of the passage of Semen through the elongated and constricted cervix. The patient being now so well, the menstrual flow occurring so regularly, freely and painlessly, there is every reason to believe that she will soon have her wish of maternity fulfilled. - This operation was first brought into prominence by Lisfranc, who operated 99 times. He gave many favor- able results from his operations, but his student Panby,” who saw his numerous cases, states that the results were not always so favorable, and that several of the cases proved fatal. -- It is of undoubted utility in proper cases, and the case related, as proven by the result, belongs to this category. —º-o-º- Cases IIIustrative of the Value of the Air-Exhaust- ing Apparatus in Acute Diseases. BY J. BRADLEY, M. D. St. Marys, Ohio, CASE 1.-Mr. M., aged 16, Pleurisy—was taken ill in the evening and sat up all night in an arm chair. Called the next morning, I found his temperature 1033°, pulse 112, respirations 50, with severe pain in the left side. I applied six wet cups and ordered veratrium. On my visit that evening I found him no better. Ithen applied my exhausters as he sat ; in about five minutes he said “I feel the pain going away,” and in a few minutes more the pain was entirely gone. In about an hour I took them off and laid him down—gave a Dover's pow- der with hot bricks to his feet. This ended the treat- ment—he was well the next day. CASE 2.—Mr. B., a laborer in a spoke factory, aged 17, Pneumonia—was taken ill 10 o'clock A. M. I was called the same evening; found his heat 104°, pulse 118, respirations 40, with dyspnoea that gave him much alarm. I applied my exhausters at once. In a few minutes he said “I can breathe easily.” After about an hour I took them off, and administered a Dovers powder; applied heat to the feet as before. The treat- ment ended here—he resumed work at noon the next day. CASE 3.—Mrs. M., aged about 35, a country woman, large and lax: Pneumonia—I was called the next morn- ing. Found her temperature 104}*, pulse 120, respira- tions 40, with deep seated pain in the right side, and almost constant dry cough. I at once applied my ex- hausters, which in about an hour relieved her of the pain and cough entirely. They were again followed by * Panby Maladies de l'Utérus, Paris, 1836. 146 [MAR. 30, 1872. T TH THE CIT I INT I. C. *- Dover's powder and hot bricks as in the other cases. On my morning visit I was told that the pains, cough, and fever had returned in the evening, and she had had a bad night. Temperature at visit 102},” pulse 112, respirations 40, as before; pain severe and almost con- stant. I again applied my exhausters at the same time giving a little antimon. tart. which soon brought her near a fainting condition. I kept her in this condition about an hour and a half relieving her of all pain and cough as before, but this time permanently. On leaving I found her temperature 99°, pulse 112 as before, but small and soft. The next day I found her sitting up out of bed, pulse 80. She was well, except a little dry cough. Now I ask what other treatment could have been used in the above cases with such favorable results? And these are not isolated cases. Such resnlts have followed in every instance where I have used the air- exhausting apparatns, previously described, when it has been applied on the first or second day of the attack. —-º-º-º--— DIGITALIS, Its Action on Circulation and Temperature. JBY PROF. ACKERMANN. From the Berlin. Klin. Wochenschrift, Jan. 15, 1872. The physiological action of digitalis upon the circula- tion has been subjected by Traube, as is well known, to most searching and accurate investigation, and the chief points established by a great number of experiments beyond the shadow of doubt. Based on a short reca- pitulation of the most essential results of his investiga- tions, Traube formulises the theory of the physiological action of digitalis on the circulation as follows: Digitalis acts, 1. Exciting and in further course depressing on the inhibitory nervous system. 2. Exciting and in further course depressing on the vaSO-motor nervous system. 3. Depressing on the cardiac muscles. Five years ago I made a tolerably long series of ex- periments—with a defective kymographion, it is true— on the effects of digitalis on dogs. Since the results of these experiments agreed in all essential points with Traube's and did not contain anything new of impor- tance there was no justification for their publication. Later experiments, however, undertaken with Sander- wald's kymographion, made accurately after Traube's description, have furnished further results, have led Inore especially to a conclusion as to the connection which seems to exist between the changes in the circu- lation and the long known action of digitalis on animal temperature. 1. Action on the Circulation. Quite constantly is observed, immediately after the injection of a large dose of digitalis (0.05) into the jug- lar vein of the dog a diminution of the frequency of the pulse which is always attended with an increase of the individual pulse waves. Traube has already referred this diminution of pulse frequency to an irritation of the inhibitory nerves of the heart, without having been able, however, to adduce any absolute proof for his view. Retardation of the pulse ensues—as Traube himself con- fesses—even where section of the vagi has been per- formed before the digitalis has been administered, so that Traube—in protection of his theory—was forced to the belief that the retardation after division of the vagi was effected from the peripheric extremities of the divided nerve. That this view was correct is proven by means of an agent which has the power of perfectly paralysing the heart fibres of the vagus. Such a substance, as Bezold has discovered, is atropine. If this substance be injected in sufficient quantity (usually 0.010–0.015 suf. fice) the pulse frequency is not at all retarded by digitalis. - < .. After this pulse retardation ensues, sometimes quite suddenly, oftener gradually, an increase of pulse fre- quency far above normal. This has been ascribed by Traube, likewise correctly, to a paralysis of the vagi. But it is only in part affected in this way; for this in- crease in frequency is also observed when the vagi have been perfectly paralyzed by the previous administration of atropia. We must therefore conclude that this frequency of the pulse under digitalis depends, besides upon paralysis of the vagi, upon a stimulation of the musculo-motor apparatus or the acceleratory nerves of the heart. - *. After this acceleration of pulse frequence follows, then, quite frequently, yet not constantly, a second re-. tardation usually associate with great irregularity. This seems to depend upon a beginning paralysis of the heart muscle, and, when it occurs, it usually passes away suddenly into a complete arrest of the heart's action. This arrest of the heart's activity which may ensue upon the acceleration of the pulse, even, indeed, upon the primary pulse retardation, is absolutely independent of the action of digitatis upon the inhibitory nerves. It seems to be favored by the direct contact of the drug with the muscular substance of the heart and is with- out doubt based on a paralysis of the musculo-motor apparatus. Immediately upon its occurrence the heart reacts no longer, as Stannius has long ago demonstrated, to electric excitation. - Regularly is observed, further, after the injection of digitalin, an increase in the arterial pressure, usually very marked. This phenomenon is entirely independent of pulse frequency, as it may be present or absent with every grade of frequency. It is caused, anyhow in part, perhaps entirely, by vaso-motor excitation, for it is ob- served in less degree where the cord in the region of MAR. 30, 1872.] TIEI IEH C T , T N T C . 147 the atlas has been previously divided. Whether it be alone brought about by vaso-motor excitation or whether the heart also does not take part in its produc- tion could not hitherto be definitely determined. This increase of pressure may pass, with every grade of pulse frequency, into a diminution of pressure down to or below the normal, in consequence, to great extent, certainly, of paralysis of the heart muscle. In the beginning of the primary retardation also, a diminution of pressure below the normal may occur owing to the fact that at the time of vagus excitation the vaso-motor excitation is absent. The diminution of pressure, then, is to be regarded as the direct consequence of vagus irritation. - As it is well known there are very often observed in experiments in blood pressure regular, peculiar varia- tions, much slower than the pulse, whose cause, accord- ing to Hering's investigations, is to be sought in the con- nection between respiration and cardiac action. These variatioſis, which in antithesis to the primary pulse waves may be denoted as secondary waves, are likewise retard- ed by injections of digitalis and in the same relation as the pulse, i.e., the number of the pulse waves following a secondary wave remain the same before and after retardation. - 2. Action on Temperature. In my former investigations as to the effects of large doses of digitalis upon animals I made a great number of observations upon the temperature of the rectum in the hope of discovering the connection between the circulatory changes and the well known antipyretic effect of digitalis. These attempts were utterly fruitless. The reason of this failure, as I have since convinced myself, was not because a reduction of temperature does not follow after large doses of digitalis, but because, as Heidenhain has already shown, the rectum is an un- suitable place for the observation of temperature. It is necessary to obtain the temperature of the blood in a large blood vessel and I have lately made a number of experiments in which I have observed the temperature of the blood under the action of digitalis in the ascend- ing cava by means of a Heidenhain thermometer. These experiments have furnished positive results. The temperature sinks with the increase and ascends again with the diminution of pressure even above the normal, beyond the pressure at the commencement. So far as my experiments hitherto justify a conclusion it seems that the loss of heat occurs most rapidly and markedly when the pulse had been frequent and small and the pressure low before the remedy was administered. If, then, in consequence of the digitalis, a marked retardation of the pulse occurs simultaneously with con- siderable increase of pressure, the loss of heat is very great. It is less when the pulse becomes frequent under unchanged or even diminished pressure. These results, however, need further experimental confirmation. Heidenhain has already shown that the reason of the temperature reduction in connection with increase of arterial pressure depends, most probably, on an increased rapidity of the motion of the blood in the capillaries. This view does not by any means coincide with Weber's theory of the motion of the blood ; for the greater the difference in pressure between the arteries and veins [i, e., the higher it is in the arteries] so much the more rapidly must the blood pass from the arteries to the veins. • Traube, in his latest already mentioned communica- tion, has attempted to explain the action of digitalis in many heart affections by the physiological effects of this agent upon the circulation. The effect of this drug, as is well known, is most marked in insufficiencies and stenoses of the left ostium venosum. Venous hyper- ‘aemiae with corresponding anaemia of the aortic system, are natural to this condition and are, with their con- sequences, diminished or allayed by a greater distension of the aortic system with blood. Such a distension we can induce by means of digitalis and when induced it is mostly, perhaps solely, the effect of vaso-motor irrita- tion. This causes increase of pressure in the arteries, a more rapid motion of blood in the capillaries and diminu- tion of the venous pressure. The consequence of all this is that retreat of the transuded fluids into the capillaries and veins so often a fact of clinical observa- tion, a thinning of the blood and an increased secretion of urine which is also immediately favored by the in- creased pressure in the arteries. Traube has also dem- onstrated that in consequence of this retardation of car- diac contractions the nutrition of organs is favored. The antipyretic action of digitalis finds a sufficient ex- planation in the loss of heat connected with inerease of pressure. Finally, I have to mention with gratitude that my honored colleague Prof. Aubert has favored me through- out these investigations with his counsel and assistance. –-nº-e-Qº--- SCIENTIFIC NOTES. THE GERMS OE HEALTHY BLOOD.—The last number of Stricker's Jahrb. contains an article “On the Presence of Fungi in the Blood of Healthy Men,” by Adolph Lor- storfer. Lorstorfer drew blood from the fingers of eleven people who considered themselves in perfect health with every precaution to avoid contamination with dirt, and examined the specimens daily with a Hartnack microscope, ocular 3, objective 10. During the first two days he observed nothing remarkable, except in some cases a few scattered groups of small granules. On the third day similar groups were always found, though still scattered. The granules were of equal size, consid- erably larger that those of the colorless blood corpuscles, but without any definite arrangement. On the fourth day they had increased in size, and were arranged in groups of four, so as to resemble the well known Sar- cind ventriculi, On the fifth day the granules had slightly 148 [MAR, 30, 1872, TIEI IE C T , I INTI C. increased in number and size, but after this date no change was observable up to the tenth day, when the preparations became unserviceable. Lorstorfer thinks his experiments render it probable that the germs of Sarcina ventriculi exist in the blood as a natural condi- tion. THE ABUSE of ALcohol AND Tobacco As A CAUSE OF AMBLYOPIA. By Dr. L. Hirschiller, of Pesth.—The author appears to have had large experience among the intemperate, and gives the following résumé of symp- toms of amblyopia a potu : - Objects appear as if under a veil, and this dimness comes on suddenly. They are apt to swim and tremble; persons faces seem to the patient to be bluish or yellow; glistening, metallic surfaces are badly discriminated ; only large print (Jaeger 14–20) can be read; at first it seems clearer than it does after looking a short time; objects soon grow hazy and utterly confused. Vision is worst at mid-day, and best at twilight and by artificial light. To external inspection there is nothing abnormal, ex- cept perhaps slight conjunctival catarrh. The pupil is contractile, and is quite indisposed to expand. Visual field is intact. Central Scotoma is rare. By the ophthal- moscope the nerve may be normal, or slightly reddened, or of a dirty gray; at the latter stages it may be white, and indicate beginning atrophy. The amblyopia soon reaches its maximum, and remains for a long time unchanged. & Amblyopia from tobacco differs little in symptoms from the above. The proneness of the pupil to contract is sometimes remarkable. Amblyopia from other causes, as menstrual troubles or rheumatic processes, etc., etc., may present precisely similar symptoms. The pathology of the disease the author is disposed to locate in the brain-tissue. For treatment, the author relies on entire abstinence from the use of alcohol and tobacco, and a general hygienic method. Local depletion does little good. Attention to digestion, exercise, and fresh air, are most essential. —Archiv. für Oph., a vii., 1, 221. ———º-º-º--— Experiments Demonstrating that the Hair of Man may change rapidly from Black to White. - BY BROWN-SEQUARD. From the Archives de Physiologie, May, 1860, p. 442. It is still a question whether the hair of the head and beard may change color rapidly, as many facts would seem to show. It has even been affirmed that the change from black to white may take place to greater or less extent in the hair or beard in a manner almost suddenly. I do not wish to discuss the question as to what faith may be attached to the assertions, for the most part, of persons of no scientific authority.* I propose only to re- port some experience which leaves no doubt whatever as to the possibility of a very rapid change of color in the human hair. ** In the month of August I first observed the appear- ance of a few white hairs in my beard in the midst of both cheeks, anteriorly. The posterior portions had already been sprinkled with white hairs for several years but up to the period I am about to mention there had been none upon the anterior part of the cheeks. On awaking one morning I observed a few white hairs on this anterior part where they had not before been seen. I then conceived the idea of extirpating these hairs of latest appearance (there were only five on one side and seven on the other) to observe whether hairs of similar color would reappear. I had not long to wait. In the midst of the hairs of this part of my face, black or deep brown in their entirelength and a few others white only at the root, I found two days after the epilation men- tioned three hairs on the right side and two on the left white in their entire length. The result of this experiment was not doubtful. But in order to be more sure of the facts I had observed, I repeated the experiment several times during the five or six weeks following and on each occasion I had the opportunity of observing the black hairs become white in their whole length in from two to five days. I need hardly say that the hairs commenced to whiten in the neighborhood of their roots. I was then in my ordinary condition of health and was not under the influence of any mental disturbance. Thus, without any appreciable cause other than that incidental to a certain age there occurred in my case a very rapid change of color from black to white in a considerable number of hairs. So far as I could deter- mine this change occurred, in every instance, in the night. I made no microscopic examination of the white hairs. • These experiments leave no doubt whatever of the possibility of a very rapid transformation (probably in less than one night) of black into white hairs. —-º-º-º-- MIEDICAL NEWS AN INTERNATIONAL MEDICAL CONGRESS IN 1873.− It is intended to hold an International Medical Congress in Vienna in 1873, under the protectorate of the Arch- duke Rainer. This will be the third assembly of the kind; the first having been held in Paris in 1867, and the second in Florence in 1869. The programme com- prises several important subjects in public medicine; viz., vaccination, quarantine (especially in cholera), the regulation of prostitution, and the sanitation of large towns. There will also be brought forward for discussion *I would refer those who would learn existing knowledge on this subject to the excellent treatise of my friend Charcot, published in 1861, in the Gazette Hedomidaire, vol. viii p. 445. * * * * * ... . . . * ~ * ~ * * MAR. 30, 1872.] T EH. H. C. T.I. NI c. 149 proposals for an International Pharmacopoeia, and for the establishment, as far as possible, of uniformity of medical education in all countries, with consequent reciprocity in the value of diplomas. CONQUEST OF ALSACE.-The Germans who openly | proclaim their universities as among the most effective of their means of conquest, have made arrangements for establishing an university at Strasbourg. An imperial credit of 200,000 thalers will be opened for 1872; and to this will of course be added the receipts from the students and provincial subscriptions. It is intended that there shall be forty-two ordinary and twenty extra- ordinary professors in the university. Among the ordinary professors are some names of European rep- | utation; viz., Waldeyer (Anatomy); Hoppe-Seyler (Physiological Chemistry); Von Recklinghausen (Path- ological Anatomy); Schmiedeberg (Materia Medica); Leyden (Medicine); Lücke (Surgery); Gusserow (Mid- wifery); etc. It is openly proclaimed that the professors appointed have accepted their perhaps not very enviable posts as a patriotic duty. The organisation of the faculty of medicine is not yet completed; but it is intended to open the university at the commencement of next sumnºr session. “INDEx To PRICES” is responsible for the following.— The demand for human hair is so great that it is im- possible to supply it. Price has risen to 16s. a pound. As much as 1,000 dols, has been offered for a “head of hair” six feet long. Some ladies dress fifty to sixty miles of hair every morning. ST. PAUL AND ST. LUKE.-‘‘Honor a physician with the honor due unto him for the uses which ye may have of him; for of the Most High cometh healing, and he shall receive honor of the king. The skill of the physi- cian shall lift up his head, and in the sight of great men he shall be admiration.”—In the new Lectionary, this is the commencement of the evening lesson on the day sacred to St. Luke, the evangelist and physician. But the Lord Chamberlain is apparently of a different opinion. . We counted about fifteen hundred clergy in St. Paul’s cathedral at the public thanksgiving, some hundreds of soldiers and lawyers, and about one dozen invited members of the medical profession. There were one hundred and four members of the London Board of Works invited; but neither the Council of the College of Surgeons, nor the General Council of Great Britain and Ireland. Against the hundred and four tickets sent to the Board of Works may be counted two sent to the University of London, one to the College of Physicians, and one to the College of Surgeons. In the official statement by the Lord Chamberlain of the professions represented, that of Medicine is not even mentioned. Accipe dum dolet is a motto long ago recommended to the profession by a shrewd observer. Lord Sydney gives a new force to it, by excluding the profession from an adequate representation on this occasion of public re- joicing, to which they were not altogether foreign, and in which their official representatives would not have been misplaced.—Brit. Med. Journ., Mar. 2, 72. American Medical Association. * The twenty-third Annual Session will be held in Philadelphia, Pa., May, 1872, at 11 A. M. The follow- ing Committees are expected to report: On Cultivation of the Cinchona tree, Dr. Lemuel J. Deal, Pennsylvania, Chairman. On the Anatomy and Diseases of the Retina, Dr. R. F. Mitchel, Alabama, Chairman. On the Comparative Pathology and the Effects which Diseases of Inferior Animals have upon the Human System, Dr. Geo. Sutton, Indiana, Chairman. On the Structure of the White Blood Corpuscles, Dr. J. G. Richardson, Pa., Chairman. On Vaccination, Dr. T. N. Wise, Kentucky, Chairman. On Skin Transplantation, Dr. J. Ford Thompson, D. C., Chairman. . On the Nature and Process of the Restoration of Bone, Dr. A. L. McArthur, Illinois, Chairman. On Some Diseases peculiar to Colorado, Dr. John Elsner, Colorado, Chairman. On Correspondence with State Medical Societies, Dr. N. S. Davis, Illinois, Chairman. On National Health Council, Dr. Thomas M. Logan, California, Chairman. On Nomenclature of Diseases, Dr. Francis Gurney Smith, Pa., Chairman. On What, if any, Legislative means are Expedient and Advisable, to Prevent the Spread of Contagious Diseases, Dr. M. H. Henry, New York, Chairman. On American Medical Necrology, Dr. J. D. Jackson, Kentucky, Chairman. On Medical Education, Dr. J. S. Weatherly, Alabama, Chairman. 4- On Medical Literature, Dr. Theoph. Parvin, Indiana, Chairman. On Prize Essays, Dr. Alfred Stille, Pa., Chairman. On the Climatology and Epidemics of New Hamp- shire, Dr. G. R. Crosby; Vermont, Dr. G. B. Bullard; Massachusetts, Dr. E. Cutter; Rhode Island, Dr. Edw. T. Caswell; Connecticut, Dr. J. C. Jackson; New York, Dr. W. F. Thoms; New Jersey, Dr. E. W. Hunt; Penn- sylvania, Dr. W. R. Wells; Maryland, Dr. C. H. Ohr; Georgia, Dr. A. J. Semmes; Missouri, Dr. W. S. Edgar; Alabama, Dr. R. F. Mitchel; Texas, Dr. S. M. Welsh; Illinois, Dr. David Prinoe; Indiana, Dr. Dugan Clark; District of Columbia, Dr. J. W. H. Lovejoy; Iowa, Dr. J. Williamson; Michigan, Dr. S. H. Douglas; Ohio, Dr. J. A. Murphy; California, Dr. F. W. Hatch; Tennessee, Dr. W. K. Bowling; West Virginia, Dr. E. A. Hil- dreth; Minnesota, Dr, Chas. N. Hewitt; Virginia, Dr. A. G. Wortham; Delaware, Dr. L. B. Bush; Kansas, Dr. Tiffin Sinks; Mississippi, Dr. J. P. Moore; Louisi- ana, Dr. S. M. Bemiss; Wisconsin, Dr. J. K. Bartlett; 150 [MAR. 30, 1872. -T H E C T.I. N. T. C. Kentucky, Dr. L. P. Yandell, Sr.; Colorado, Dr. R. G. Buckingham; Oregon, Dr. E. R, Fiske; North Car-|. olina, Dr. J. F. Haywood; South Carolina, Dr. M. Simmons. Physicians desiring to present papers before the Asso- ciation should observe the following rule: “Papers appropriate to the several sections, in order to secure consideration and action, must be sent to the Secretary of the appropriate section at least one month before the meeting which is to act upon them. It shall be the duty of the Secretary to whom such papers are sent, to ex- amine them with care, and, with the advice of the Chairman of his Section, to determine the time and order of their presentation, and give due notice of the same.” OFFICERS OF SECTIONS.—Chemistry and Materia Medica.--Drs. R. E. Rogers, Philadelphia, Pa., Chair- man; Ephraim Cutter, Boston, Mass., Secretary. Practice of Medicine and Obstetrics.--Drs. D. A. O’Don- nell, Baltimore, Md., Chairman; Benj. F. Dawson, New York, N. Y., Secretary. Surgery and Anatomy.—Drs. John T. Hodgen, St. Louis Mo., Chairman ; W. F. Peck, Davenport, Iowa, Sec- retary. Medical Jurisprudence, Hygiene, and Physiology.—Drs. S. C. Busey, Washington, D.C., Chairman; E. L. How- ard, Baltimore, Md., Secretary. Psychology.—Drs. Isaac Ray, Philadelphia, Pa., Chair- man; John Curwen, Harrisburg, Pa., Secretary. Secretaries of all medical organizations are requested to forward lists of their Delegates, as soon as elected, to the Permanent Secretary. Railroad and hotel arrange- ments will be announced at an early date. Address W. B. Atkinson, Permanent Secretary, 1,400 Pine Street Southwest corner Broad, Philadelphia. —sº-º-º- Bogus Medical Colleges. REPEAL OF THE CHARTERs of the Philadelphia University of Medicine and Surgery and Eclectic Med- ical College of Philadelphia.-The unblushing effrontery with which Paine, of the Ninth Street concern, and Buchanan, Hylton & Bissell, of the Pine-Street shop, have conducted their nefarious business has at last re- ceived a permanent quietus by the joint action of the Senate and Assembly of Pennsylvania. In November last the Herald and general press made a combined attack on the nuisance, and the sweeping erpose then made reached even the ears of the law- makers at Harrisburg, and an investigation was at once ordered. The Committee of the Senate had one or two sessions here and others in Harrisburg, and, so over- whelming was the evidence against these individuals, that the Senate on hearing the report of the Committee, voted unanimously to repeal their charters. Senator Bandall, Chairman of the Committee, was satisfied from the first that the .. made by the press were genuine, yet he gave the professors (?) every opportunity to prove their innocence. Death of a Well Known Physician. : NORTH LEWISBURG, CHAMPAIGN Co., O., Mar. 26,- Dr. H. C. Foster of this place, who was thrown from his buggy several weeks ago and suffered a broken leg just one inch below the hip, died from his injuries this morning. A strange feature of this case is, that after he found he could not get well, he telegraphed for his brother to come and see him, who immediately started, but taking the ill-fated train on the Pan-handle road, which was thrown from the track near Altoona, Pennsylvania, last Friday, he also received a broken leg similar to that of the Doctor’s. THE SYPHILIs CoMMITTEE.—The committe appointed by the Vienna Medical Society to examine and report on Dr. Lostorfer's researches on syphilitic blood has been dissolved, the members nominated having declined to accept the duty assigned to them. —-º-o-º- CORRESPONIDENCE. NASHVILLE, IND., March 18tlı, 1872. EDS. CLINIC : : - I submit herewith a brief report of a case of foetal deformity that has come under my notice since my return from your city. It is not the peculiarity of deformity that has arrested my attention so much, as we find almost every grade of deformity mentioned in our literature upon this subject, but it is the cause, which appears most certainly to have produced it in this case; one that I have not seen alluded to in any medical work, nor heard men- tioned as being productive of this particular type of malformation. Mrs. H., American aged 23, medium stature, was delivered unaided of her third child, a female, on the 6th inst., after a somewhat tedious and severe labor, Dr. J. S. Arwine of Columbus, Ind., attending her. The child was well formed in every way as far as could be observed except that the parietal bones, occipital bone and frontal bone, were but partially developed. The bones forming the nose were almost entirely want- ing; a small tubercular eminence representing the point of the nose, pierced on either side by exceedingly small openings, the external nasal orifices. The eyes appeared to be well developed, but the lids coalesced so they could not be separated without surgical interfer- ence. The bridge of the nose was depressed below the level of the eyes. - 1 * This case occurring in the family where I had been making my home, I was immediately shown the child which was still alive, and presented the deformities above alluded to. It was deeply cyanosed, respiration being quite feeble and irregular. It made frequent attempts to cry, but seemed unable to utter an audible sound. I was informed by the nurse that it had only made similar efforts since its birth. I administered some milk and water prepared for the purpose, a small ‘MAR. 30, 1872.] TIEEI IEL, C T , I INTI C. 1.51 quantity of which it swallowed with great difficulty. Respiration was almost entirely performed by the mouth in consequence of the minuteness of the nasal orifices. |. It lingered about three hours after my arrival when it was attacked with a light convulsion and expired. The child’s head presented the evidences of a con- striction by a substance corresponding in size to an or- dinary umbilical cord. I wrote to Dr. Arwine in ref. erence to the condition of the child at birth and received the following reply: “The child was wound up in the cord in the following manner. The funis passed around the right side of the child, under the left axilla and twice around the neck, and I am fully convinced by its shortness interfered very materially with the expulsive efforts of labor and protracted the case very much. My opinion is that the cord was originally around the head and was forced from its imbedded position during the progress of labor down around the neck. The cord constricted the head, I think, and arrested the full de- velopment of the particular bones misshapen or absent, and occasioned the deformity in question.” I may state that Dr. Arwine is an old practitioner of undoubted ability, a graduate of the Medical College of Ohio in ’52 or ’53 and a reliable man in every respect. Now we have as a proof of the cord having been the prime cause of the deformity, a hollow depression ex- tending around the occipital bone about the region of the superior curved line, also an indenture in the mid- dle of the helix of each ear, a depression at the external margin of each orbit and the obliteration of the bridge of the nose ; a line corresponding, thus, quite well to a circle drawn around the head in those regions. These furrows bore evidence of having been produced by a cord of the size of the navel-string. Beneath and above this apparent constriction was the want of development spoken of The integument was perfect and there was a sufficient growth of hair over the scalp. Is it not very probable that in this case the cord was looped about the foetal head during the early months of gesta- tion, and as the development progressed the cord became constricted about the head, produced these marks, de- pressed the nose, caused the adhesion of the eyelids, and by the constriction arrested the nutrition and develop- ment of the parts found absent. I attended this lady in her two former confinements, both the children were males, Small but well formed. The labors were short and characterized by less pain than is the rule. I would like to have the opinion of THE CLINIC upon this matter. Yours, etc., J. W. Duncan, M. D. There is no ground for any other theory in explana- tion. It certainly was not an anencephalic foetus for mention is made of the presence of the scalp in situ. The furrow and agenesis of bones described, might have been produced, it is true, by a false band from the membranes which escaped observation, but as it is ex- pressly stated that the cord was exceedingly anomalous in its course the view expressed is far more plausible. From any of the works of reference at hand we do not discover an exactly similar case. A case of absence of the frontal bone and superciliary arch is reported in the Revue Méd. vol. xi, p. 146, 1821. It was a case, how- ever, in which the placenta was adherent to the scalp. The following extracts elucidate other points of interest in the case: The usual length of the cord is about that of the foetus 18–20 in. It is far oftener longer than the normal than shorter. Baudelocque mentions a length of 58 in. ; Morlame of 60; L'Heritier and Schneider have reported a length of over 9 feet! (3 mêtres).” This excess of length favors (1) the accident of twisting of the cord around the neck or limbs of the child; (2) the formation of knots; (3) prolapse of the cord. All these may become causes of dystocia. (1) The encircling of the neck, which is by far the most frequent form, was formerly thought to have been due to active motions of the child. Sieboldt attributed it to the fact that the arm left the body and carried the cord with it. Simp- son, having noticed that the circles generally passed over the right shoulder towards the left, attributed the cause to a greater force of the right umbilical artery; this was strengthed by a future observation, in which the cord passed from the left shoulder towards the right, when an opposite version was also found in the cord. Generally the cord forms but one circle. Schneider has seen 6; Baudelocque, 7; Credé, 8; and Gray, 9. They occur, too, more frequently than is generally supposed; thus Devilliers has observed them 3 times in a hundred cases, Churchill between 9 and 10. Weid- man's proportion ran 123 to 100; Verrier, 18.3; Mayer, 19; and Beale, 20, in the same number. Walcher con- sidered that it was only in the rarest case that they proved dangerous to the life of the foetus, because the placental insertion of the cord descended with each con- traction of the uterus. Veit has shown, however, that partial and total asphyxia not infrequently results from constriction of the trachea. “The infant literally com- mits suicide,” says Monro. Gardien was the first to prove that death is induced more frequently by the interruption of the circulation. Velpeau is scarcely disposed to admit this, but Monod, Taxil, and Hillairet have placed it beyond doubt, by showing that the neck may be so compressed as to leave deep grooves upon its surface; in the case of Taxil, the neck was reduced to 4 millimetres (?) in thickness. In these cases death occurs, of course, before labor; in the rule, however, death only supervenes in labor when the grasp of the halter is tightened. * Manuel, Pratique De L’Art des Accouchements. 1867. f Siebold, De Circumvolutione Funiculi Umbilicalis. 1834. I Klob (Path. Anat.). Verrier, Paris, Göttlingen, 152 [MAR. 30, 1872. T EC H C T I IN TC. The cord may encircle the neck or limbs, moreover, when its length is perfectly normal, or even shorter than normal; thus, Spaeth observed the cervical circle once in a cord measuring but 13% in, length. That the cord, when entwined about the limbs of a child, may amputate the limb, is a fact with which we have long since been made acquainted by Montgomery, who has reported a number of interesting cases in the essay on “Spontaneous Amputation in Utero.” Schwabe has also reported a case of amputation of the leg of an embryo of three months just above the ankle-joint. Braun thinks this impossible, as death would result sooner by obliteration of the calibre of the vessels in the cord, whereupon Klob pertinently remarks that it is questionable whether even the pulsation of the cord might not be sufficient to divide the delicate structures of an embryo at this period. Finally, cases are not wanting in which the cord has passed down between the limbs, traversed the length of the back, and then encircled the neck. Streeter* has demonstrated that many cases of pre- ternatural presentation may arise from abnormal length of the cord, particularly when twisted about the neck or limbs. —sº-C-º- C. L. (NICAL VIEN (OIRAN IDA. SUB-CUTANEOUS ASPIRATION IN STRANGULATED HERNIA.—To the facts pertaining to this subject which we have already registered we add the following taken from the inaugural dissertation of M. Dr. Autun. It adds additional lustre to the happy results already ob- tained by the instrument of Dieulafoy. Some time ago Dr. Dugue, physician at Mans wrote to M. Collin (Charrière) that in a case of strangulated hernia Dieulafoy's aspirator had furnished remarkable results. The facts, as related, are as follows: My confrère and friend Dr. Bourdy came a few days ago to take me to assist him in an operation for strangulated hernia which he was about to perform on a woman in the suburbs of Mans. It was a case of left inguinal hernia, strangulated for four days. It was an enterocele. The intestine greatly distended and resistant contained gas and fluid. Before operating we wished to try the aspirator. The needle (No. 1) being plunged into the intestine, the body of the pump very rapidly filled itself with gas and liquid and the tumor subsided very rapidly, becoming soft and flaccid. We believed then that the reduction would be easily effected ; this was unfortunately not the case, the hernia remained adherent. M. Bourdy proceeded to operate immediately. The intestine having been exposed, it was impossible to find the point of puncture and during the operation and at the moment of reduc- tion there escaped from the intestine neither a drop of liquid nor a bubble of gas. The adhesions having been *w- ºr ~ * * Lee's Midwifery, p. 122. broken up, the intestine was returned with the greatest facility. Some hours after the operation, under the influence of a purgative (30 grim. ol. ricini) fecal dis- charge was reestablished, and on the next morning we found our patient in the most Satisfactory condition. There was no fever, pain nor cramp, the abdomen was flaccid and supple. This fact, although the success was incomplete on account of adhesions, would seem to demonstrate conclusively the impunity with which the intestine may be punctured and the absence of all danger in reduction after this puncture—These de Paris–Bull. Therap., Jan. 30, 72. —-º-º-º- Aethylidenchloride. BY A STEFFEN, (Stettin). From the Berliner Klinische Wocheuschrift, Feb. 5, 1872. At the congress of German physicians and physicists held at Rostock in September last the wish was ex- pressed that I should publish my experience with athylidenchloride in the children's hospital at Stettin. I do this now the more readily because the employment of this agent seems to me to have been hitherto very limited. - We have used the remedy during the past few months Some twenty times in children and once in the adult. Its inhalation is effected just as simply as the inhalation of chloroform. Since aethylidenchloride has a pleasanter and milder odor than chloroform and does not irritate the skin to the same degree, children resist it much less, older children almost not at all. To attain the most rapid effect, as much as possible must be inhaled in the beginning. Its effect is as follows: Children are rendered perfectly unconscious in two, at most in three minutes. On two occasions in which I cut through a number of lupus facei papules there occurred no loss of consciousness but there was perfect anaesthesia in the diseased parts so that the sections were entirely void of pain. If the patients are not restless before inhalation no accelera- tion of the heart's action manifests, and as little is respiration affected. Patients present the appearance of a quiet sleep. The effect of aethylidenchloride is of shorter duration than that of chloroform. In operations, therefore, requiring considerable time, the anaesthetic must be reinhaled as soon as signs of consciousness manifest. In childhood, for operations of short duration an average of three or four grammes [45-60 grs.] is fully sufficient. In the case of a woman, on the other hand, operated on for carcinoma mammae by a physician of this city, where the extirpation could not be effected at once but only in piece-meal manner, about thirty grammes were employed. MAR. 30, 1872.] T IEET THE C T , T INTI C. 153 So soon as the effect of the agent subsides the patient recovers rapidly without experiencing any inconve- niences whatever. Children, in the rule, as soon as they recover consciousness call for their dinner. In adults also all effects disappear quickly and without any inconvenient consequences. Vomiting during or after inhalation occurs in children only in exceptional cases. If we compare the action of aethylidenchloride and chloroform we must admit that the former is to be pre- ferred on account of its prompt effect, further, because it seems to be less dangerous as the heart's action and respiration are not influenced, both of which are decidedly, often dangerously, affected by chloroform. Finally, aethylidenchloride deserves the preference because patients recover from it so speedily and without subsequent disagreeable sequelae. The objection that aethylidenchloride is more evanescent in its action is overcome by the more frequent repetition or the longer continuance of its inhalation. An essential objection to it at present is its high price. This, it is to be hoped, will soon alter itself. - With this experience, I do not hesitate to give aethylidenchloride the decided preference over chloro- form and to recommend its use most warmly. —-º-e—sº- Intermittent Blepharospasm. BY DR. A. SEELIGMULLER (Halle). From the IClinische Monatsbl. f. Augenkeilkrande, Aug. Ó Sept., 1871. (Schmidt's Jahrb., Feb. 4th, 1872). We make an abstract of the following case on account of its rarity, as a contribution to nerve pathology of such extraordinary interest. A countrywoman, aged 57, suffered for 30 years from a peculiar spasm of the lid. During her time of service she suffered many times from rheumatic tooth-ache by which the most of her teeth had dropped out. During such an attack she spent a night in a cold room so she was obliged to be taken home stiff and paralysed. The cold disappeared after sweating, but soon after at times in sewing and knitting dimness of vision came on which imperceptibly became changed into a convulsive spasm of the lids. Different therapeutic measures were resorted to, among others, division of both supraorbital nerves, without effect. Pregnancy, etc., had produced no change. During the climacteric period other nervous troubles had come and gone. Pure hysterical attacks, however, were never present. Periodic spasm of the lids appeared as follows; some- times the lids involuntarily closed two or three times an hour, sometimes as high as ten times, and remained closed one or two minutes without the patient being able to open them without the help of the hand. If the lids were forcibly opened there was violent gasping or drawing back of the head by jerks. The spasm came on especially when the patient looked down, on turning the head, chewing solid food, walking or reading, working in a bent position, deep thinking, listening to frightful stories, even from loud talking in the room. It came on oftener if the patient carried anything in both hands than if one was free. Objective examination gave, beyond numerous wrink- les in the skin about the eye, no disease of the lids or eyes. At the height of the attacks the physicians in attend- ance were unable to open the lids perceptibly. The rest of the senses were normal, excepting the sense of Smell which had been lost for two years. From examina- tions made from time to time by various physicians dif- ferent pressure points were revealed, which were painful on the slightest pressure, on an irritation of which the lids immediately came open, like the lid of a box by pressure on its spring. These points were the back teeth of the lower jaw; both supra-orbital notches; both parietal protubrances especially the left; the temporal ridge itself, the transyerse process of the upper cervical Vertebra especially the left; the upper sympathetic cer- vical ganglion ; the brachial plexuses above the clavicle and the spinous processes from the 1–8 dorsal vertebrae. Strong pressure upon the radial and ulnar processes at wrist joint produced no pain but gradual opening of lids. Other points, painful on pressure in healthy per- Sons, e. g., the sternum, the skin over the shin, had no effect on the spasm of the lids. The patient was experi- mentally subjected to treatment by electricity. The negative pole of 6 or 8 elements was placed upon the breast, the positive upon the above named pressure points. The result of the first sitting was favorable. Not only did the susceptibility to pain in the pressure points disappear, but also the spasm of the lids became much more seldom so the patient could read a long time, which was formerly impossible. A complete cure, however, was not effected, as the trouble returned in its former severity after the treatment. Cutting the gums about the teeth had already been done in Berlin without effect, and was not again resorted to. Prof. Arlt in his book has recorded four cases of this extraordinary disease, Wrecker and Mackenzie each one. Handfield Jones of London, (Studies on Functional Disorders) mentions a similar case. A very peculiar case of the same nature is given by Broadburt (Med. Times and Gaz.), where the patient’s head was drawn back and the lids were closed when he talked, the patient being free from attacks so long as he kept quiet. Alfred Graefe also saw a case in his clinic in Halle. In none of these cases was there the so-called hysterical or ner- vous temperament. This periodic spasm of the lids is not to be confounded with the continuous spasm gener- ally to be relieved by division of the supra-orbital nerve. 154 [MAR. 30, 1872. T EI IEH C T , T: N T C . Preputial Calculi.” BY J. G. KERR, M. D. Canton, China, Phymosis is not an uncommon deformity among the Chinese, and it is, of course, only in cases where this abnormal condition existed that preputial calculi could form. The cases included in this table were operated on in the Medical Missionary Society’s Hospital in Canton, and I need but refer to the simplicity and entire free- dom from danger of the operation, required for the relief of these cases, to show how utterly destitute of surgical skill the physicians of the oldest nation on the earth are, and how much need there is of giving them the knowledge and appliances of western science and art. A reference to the table will show that in every case except one the calculi were multiple. In two cases the number exceeded one hundred ; in one there were forty, and in three others there were between twenty and thirty. In one or two cases the calculi were uniform in size and shape, but, in most of those where they were numerous, there were a few large and many small ones. Some had smooth, even surfaces, while others were angular, with facets. The most remarkable of the cases was No. 7, operated on in 1862. The patient was thirty-eight years old. The prepuce was much thickened and enlarged, and the presence of calculi was easily discovered by a probe. A crucial incision was made in order to remove the stones, and the superfluous thickened skin was removed by circumcision. The calculi were two in number, and the weight one ounce and a quarter. The diameters of one were one and five-eighth by one and one-eighth inch. It had two concave facets, on opposite sides. One facet which received the second stone was smooth and polished. The concave facet on the other side was precisely like the first, except that it was slightly roughened by recent deposit. The second stone was one and a half inch in diameter, and was almost a per- fect double convex lens in shape. One of its sides, where it rested on the other stone, was worn quite smooth, and it had evidently been shifted from one side of the first stone to the other, thus maintaining the completeness of the two concave facets. The calculi from case No. 2 are in the possession of Prof. S. D. Gross, of Jefferson Medical College, Philadelphia. I will add an account of two more cases, not included in the table, because neither of them is strictly either preputial, urethral, or urinary calculus: Yip Akwong, aged twenty-one, was admitted into the Medical Missionary Society's Hospital, July 27, 1867 (then in charge of F. Wong, M. D.,) with an accu- * From the N. Y. Med. Joura., Mar., '72. mulation of calculi, in a sac half the size of a walnut, on the underside of the penis, about its middle, and communicating by a small opening with the urethra. It had existed since his childhood, but had given rise to no difficulty in passing water until recently. The sac was laid open by a free incision, and a large number of calculi removed. They were of various sizes, whitish, Smooth, and shining. Four of them were about the size of a pigeons'-eggs, with irregular surface and angles. Six were smaller, oval in shape, and angular. There were two hundred and eighty-one small pieces, varying - in size from that of a pea to a millet seed. Total num- ber, two hundred and ninety-one. The other case is, strictly speaking, one of lithotomy, but the stone was in an unusual situation: A patient, aged fifty years, from Hoi-ping District, was admitted with stricture of long standing and urinary fistulas, which he persistently asserted had existed only about one year, but the appearance of the parts indicated a much longer duration. On probing the fistulas, a . stone was discovered, located on the right side of the contracted scrotum, near the groin. The fistula was enlarged toward the perinaeum, and the stone extracted. It weighed two and a half drachms, and its diameters measured one and a half by three-quarters of an inch. Its appearance indicated that it was composed of uric. acid. Cases of Preputial Calculi. No. of Age | Date of No. of Weight. IREMARKS. Case, years. Operation | Calculi Oz. I dr. Sc. 1. 58 1856 2 2 { { 103 2 All smooth. 3 .. 24 2 I. Smooth and angular. g - # | | | | | | | | *% 6 63 1860 40 1 || 2 ||Uniform in size, shape. 7 38 1862 2" | 1 || 2 || 2 |One had two facets in * which the other (being double convex) fitted. 8 47 { { 4 9 1863 6 1 10 & 4 6 II. 1866 4 Surface rough. I2 72 1867 116 1. { { & C I3 42 1869 6 1 || 1 14 56 1871 5 Also had stone in bladder 15 8 & & 22 T 6 (; € $ I6 39 { { 28 11. 17 | 75 { { 2 § 18 39 § { 11. 2 3 large and 8 small. ACUTE SPASM OF ACCOMMODATION, ACCOMPANIED BY SPASMODIC NEUROSIS OF THE FACIAL NERVE.- An anaemic girl aged 11 who had been much engaged in sewing, was attacked with photophobia and continuous spasm of the upper half of the left side of the face. Beyond a somewhat narrowed pupil there was nothing to be observed in the diseased eye. The lids could only be slowly opened when the sound eye was closed. The left globe was painful on pressure, could not fix, objects seemed enlarged. Accommodation was only possible between 5% inches and 7 inches. The right eye was hypermetropic 1-24, left 1-13. MAR. 30, 1872.] T H. H. C.I., ITNTI c. 155 Instillation of atropia produced an improvement in a few days. - Iodine and morphine were used endermically, in- ternally iron with quinine and valerian. In six days there was a relapse. Later a blister was applied and the atropine solution continued for four-weeks. A cure was brought about and the patient could work again with the aid of convex glasses No. 24.—Dr. Gos- Sctti—Ann, d'Oculistique, Mar. Avril., 1872. —º-º-º-ºm- & Alcohol at Different Periods of Life. BY LIONEL S. BEALE, M. D., F. R. S. My conclusions as regards giving alcohol to the young are in the main not at variance with the opinions of those who advocate extreme temperance. My own ex- perience leads me to believe that the majority of young healthy people would do well without alcohol, and I believe the habitual daily consumption by young persons —even of a moderate quantity—of wine or beer, is quite unnecessary, and mere waste, while in some instances it is positively injurious to health. At the same time, there can be no doubt that in certain cases where the health fails in children, and even in infants, great benefit results from giving small quantities of wine daily for a short time. Hard-working people, students, professional men, and people actively engagéd have been advised to take stimulants, as a general rule—and some, no doubt, require them; but I believe many would enjoy very good health without any alcohol at all, while the recom- mendation that they should take plenty of claret or other light wine is bad advice for several reasons. Not only is a bottle of light wine not required, but in many cases it is actually injurious. That people who can get it will often take a bottle of light wine, and more, is quite certain; but that they require it, or that it is good for their health, will not bear discussion. Up to the age of 40 very little stimulant is, as a gen- eral rule, really desirable for healthy persons, and I ex- pect most people of average health would get on better without any. My own personal experience is this:–I was never very strong, though always able to get through a very considerable amount of physical exertion without suffering from fatigue. Up to the age of 40 I hardly ever touched stimulants of any kind, and when I did take a little I not unfrequently experienced an attack of sick headache before my ordinary condition of health was restored. Lately, however, I have found the ad- vantage of half a tumbler of ale daily; and I can bear half an ounce, and sometimes three or four ounces, of wine without suffering. I dare say, as I grow older, I may, like most persons, require a little more; but when in the country, and taking plenty of exercise, I feel very well and contented without any stimulants whatever. The experience of some members of my family who have lived to be old, and that of many persons of whom I have inquired, accords with my own. In old age, I be- lieve, stimulants are really necessary, and sometimes are even more important than food itself. I feel sure the life of many old people is prolonged by the judicious use of alcohol, and I think that some, who have been very careful all through life, take far too little stimulant when they grow old—Times and Gaz, Mar, 2, '72. --º-º-º: ==Cº-O-º- JBIOMIE NEWS. I S R A E L S. ID O D G E , MI. ID . Born Oct. 6, 1807. Died Mar. 1, 1872. When death takes from our midst one of our oldest and best known associates, “it is very meet, right, and our bounden duty” to pay a tribute of respect to his memory. Especially is it So, when as now in the death of HDr. Dodge, we mourn a personal friend and one sus- taining to us important official relations. More than forty years ago Dr. Dodge came from his early home near Marietta to attend lectures in the Medical Col- lege of Ohio. When the cholera broke out in 1832-3, the Dr. though an undergraduate commenced practice, being urged to do so by the necessities of the time and the advice of his friend and preceptor Dr. Drake. Graduating in 1834 he selected Cincinnati as the field of his life-work and from that time till his death was a patient hard-working physician, up early and down late, doing with all his might what he had to do, interrupting his labors only when by ill health compelled to do so. His judgment was good, his reading extensive, his prac- tice honest and successful. His memory will be long cherished, not so much because of professional knowl- edge and skill as on account of his kindliness of heart and readiness to help by deeds rather than words. He was in an unusual degree the friend of the poor, and in a forty years professional life spent many a day and many a night caring for those who could make him no pecuniary return. He knew the weaknesses of human nature and was ready to make excuses for those whom others censured. Personally, I never knew a man more free from “envy, hatred, malice and all uncharitableness” To the Medical College of Ohio he was a constant firm friend, even in days when many turned against the In- stitution that had nurtured and developed them. Time and again have I heard him speak of the dark days, the crises through which the College has passed, when her strongest defenders hardly dared hope that she would struggle through and beat down the opposition of ene- mies within and enemies without. He most heartily rejoiced in the successes of her present and the hopeful- ness of her future, and grew enthusiastic as he remem- bered the glories shed upon her and the profession at large by her long list, from Drake to Blackman, of 156 [MAR. 30, 1872. T E H C T, ITN I C. & eminent Professors now deceased. In the discharge of his duties as Trustee he had no individual ends to subserve, no personal animosities to gratify. Whatever measure seemed to be for the best interests of the College was sure to have his hearty support, and knowing him as I did, I know that his official errors, if there were such, were sins of the head and not of the heart. His death though sudden was not unexpected, for there had been apparent to his medical friends for very many months a progressive impairment of nervous power that taken in connection with evident arterial degenerations could be interpreted in but one way. Within a few months on at least four different occasions the Dr. had attacks, that in their loss of consciousness, facial and lingual paralysis, intense cephalalgia. etc., gave warning of the ultimate result. His last illness was of less than twenty-four hours duration. The good physician, the faithful friend, the honest man, the devout Christian “rests from his labors and his works do follow him.” - P. S. C. . The following preamble and resolutions presented by the committee appointed at the last meeting of the Academy of Medicine were adopted on perusal, “ WHEREAs, Death, has so often approached our ranks in the selection of victims, that his presence has almost ceased to be appalling. To-day he may claim one whose industry, energy, attainments and aspiration have given promise of an early opening into full manhood; to-morrow he may select another, who, in advanced age, had reached the summit of his ambition and usefulness; and “Whereas, Our familiarity with human weakness and its suffering, and man’s earthly destiny, does not allay our regrets when one dies who, for many long years, had sustained an honorable and praisewothy relation to the profession; and by his tenderness, attention and symp- athy had secured the confidence and affections of his patients; and “Whereas, It has become our duty to reiterate that Dr. Israel Dodge is dead, and to say in the sincerity of our hearts that we shall miss his presence here, that we shall miss him in our Social gatherings, in our anxious consultations, in our efforts to mitigate disease and prolong life; therefore “Resolved, That as we held him in high esteem dur- ing life, so will we cherish a recollection of his useful- ness and goodness although dead. “Resolved, That his devotion to the profession, his freedom from guile, his conciliatory disposition and the tenderness and frankness of his naturé are worthy our constant imitation. “Resolved, That we tender the family and friends of our deceased brother our heartfelt sympathies.” After the report and resolutions were read, Dr. Carson was called upon and said that he was called to see Dr. Dodge upon the day of his attack. He ascertained that at 2 P. M. of that day, the doctor while dressing, suddenly fell back unconscious, remain- ing in that condition about twenty minutes. When he recovered consciousness he complained of much pain in the forepart of his head and was found to be hemiple- gic in the left side. He remained conscious for 2 or 3 hours when he again became comatose and continued so until his death, which occurred at 5 A. M. the follow- ing day. gs The autopsy was made 30 hours after death—on re- moving the Scalp a considerable extravasation of blood was found beneath it, probably occasioned by his fall. On removing the calvarium a large extravasation of blood was found between it and the meninges. The membranes were quite firmly attached in places to the superior portion of the skull. The basilar arteries were found degenerated, especially that of the right side. A large cavity was found in the anterior part of the right hemisphere, filled with blood; the extravasation exerting pressure upon the corpus striatum. On the walls of the cavity was found a small artery, ruptured, from whence the extravasation came. There was some softening of the right hemisphere. No old clots found. The examination of the liver was of especial interest in view Óf the fact. that the doctor had suffered a number of years ago from hepatic abscess, which had discharged into the lung. On opening the abdomen the liver was found firmly adherent to all the surrounding structures by old adhesions. The gall bladder was so firmly attached to the duodenum, that it was torn off in removing the liver, though but slight force was used. The substance of the liver was a little soft but otherwise healthy. There were no cicatrices in it, and none in the diaphragm or lung. - The speaker stated that he had seen two cases of hepatic abscess before in which there were no cicatrices : in the liver on post mortem examination. * CINCINNATI, Mar. 24, '72. EDS. CLINIC : k I have asked some of the members of the Academy if they would object to my giving a weekly abstract of the proceedings for publication in THE CLINIC. They do not wish to have their remarks in print until after the minutes have been read at the Academy and cor- rected if need be. This explains why I have not left a copy with you. If I do as you request my course will certainly be severely criticised. Yours Truly, L. Wolfe, Sec. Academy. The above note explains itself. We have often been solicited by members of the Academy to publish just such an abstract as the Secretary cheerfully promised to furnish. “Several members object to the publication of their remarks until they are read before the Academy and corrected.” This would give us the minutes of the Academy just two weeks after date. In the days when canal boats and post chaises were our only means of ob- taining information, we might have been content to fill the pages of THE CLINIC with the stale news of a dis- tant city at this interval. As we can readily report the proceedings of the Academies of Paris, London, Berlin, Vienna or St. Petersburg—do it, indeed, all the time— at this interval, we shall hardly inflict upon that portion of the profession which prefers a weekly paper to a monthly or quarterly in order to keep themselves posted, the remarks made right here where our paper is published, a fortnight after date. If THE CLINIC, then, continues to present to its readers the proceedings of the medical societies of Europe and Asia in lieu of those of Cincin- nati, they will understand and appreciate the chief rea- son for its course. DIVIDED MEDICINES, PREPARED BY Divided Medicine Com'y, CINCINNATI, OHIO. The Company have the honor of bringing to the notice of the Profession, this NEw AND ExCEEDINGLY PRACTICAL METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. - The Divided Medicines are prepared by FREDERICK KRAUs, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MoR.E. - - - The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every square will consequently contain accurately measured quantities. But not only SoluRLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINEs. . - This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, ; : *, *, *, and even idoo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of prepaiing medicines. - Besides the peculiarity of THESE MEDIGINES, that they are NOT LIABLE TO SPori, BY ANY LENGTH of TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calls with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. For Samples, Price Lists, and Agencies, address +. The IDivide º - - - IECDX 2688, Or FRFDERICK KRAUS, Chemist and Druggist, Walnut Hills, Cincinnati, O. - MR. FREDERICK KRAUS: CINCINNAT1, February 15, 1871. Dear Sir—The specimens of your “ Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: - SULPH:MORPHII.......................}6 grain in each square. I ARSEN:ACID.......................... 1-20 grain in each square. “ CH IN INI ....................... 1 * * * * * * CALOMEL.............................. 34 “ “ $ 4 & 6 COPPER ....................... .3% § { - - - - ResPECTFULLY YoUBs, E. S. WAYNE, Analytic Chemist. ||||||}|| || ||M|| Fosºrrºrt's 167 EAST 34TH-ST., NEW YORK, By Special Appointment Electrical Instrument Makers to the New York State Hospital for Nervous Diseases, MANUFACTURERS OF PORTABLE - ELECTRO-MAGNETIC MACHINES, Portable Galwanic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, 1870, and May 30th, 1871. - These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery Fluid. |M|| ||||||—|| |||||} PEERMAN ENT BATTERIEs, For Hospitals and General Practitioners, ELECTROIDEs. For Eye, Ear, Larynx, Nose, Uterus, Wagina, Bladder, Rec- tum, Feet, Phrenic and Sympathetic Nerves, Eleo- trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. EXTRA (4TS FROM THE OPINIONS OF THE TWOST JEMIN ENT MEMBERS OF THIS PROFESS / O N. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “No THING CAN EXCEED THE EFFICIENCY AND CONVENIENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” - We are authorized by Prof. Hammond to announce eun- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- proved and re-modified Instruments made by our Company. * MEREDITH CLYMER, M. D., Prof. of Diseases of the Neº- vous System and of the Mind, &c., &c.—“I consider their Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prof. of Surgery, St. Louis:—“In neat- ness, compactness and efficacy, they can not be excelled.” ALFRED C. GARR, ATT, M. D., Boston :-"In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” Similar Testimonials have been received from JOHN J. CRANE, M. D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A. MURRAY, M. D.; CHAS. E. BLUMENTHAL, M. D.; E. C. SEGUIN, M. D.; ALLEN MAYNARD, M. D., Cleveland, 0.; Dr. C. WANNIE, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES KELLY, Florence, O.; Dr. JOIIN BECKER, Brighton, Iowa; Dr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes- barre, Pa.; JOHN J. CALDWELL, M. D., Brooklyn, and many other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an Electrical Instrument for medical purposes. CALL OR SEND FOR CIRCULAR AND PRICE LIST. m|ritia Are furnished to Officers and Soldiers on Government account. - I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I’ commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb—why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMES A. FOSTEER, 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cincinnati, Ohio, or 172 Jef. ferson Avenue, Detroit, Mich- SAML. P. THOMAS TAIL or, IDEALER IN English, French and Scotch . GOOD's, 34 West Fourth Street, CA.W.C.A.W.W.? TA. º i; i =# É * St. stººlſ: --- |# º | H | # ſ #. º §§ ºfflº, # # | º: # iſ lift | ## *::::= ; º ſº º:-3– 3:S * - º E-º-º: - - §§§ Sº? ##$$ºš #s : #: Eºs º º º > ---. > > 2: º- >-tº- r ===S& : ===2 ºz. - #######4 ſº §:#; Zººlºº A º "... Rºsſ. - 3::::: Zº, Nº, tº ſº.; f % Rººs 55-ºº: 23% %2. - §ºž%% ſº % • * *-* - §§2. : Zºº 22 Aft 2% --- sº -- > sº sAMARITAN HOSPITAL. GOOD The GooD SAMARITAN HOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner of Sixth and Lock streets. It is handsomely furnished throughout, and is provided with all the necessary ap- pointments of a First-class Hospital. Porticoes, with commanding views, surround the whole house, and wide halls and abundant windows secure that full and free ventilation which is so essential to health and comfort. Service is furnished by the SISTERS OF CHARITY, Under the Superintendence of the well-known SISTER ANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. The regular Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each Professor presiding over his own especial department. Patients may, however, select from the regular profession of the city any physician of their choice. The Good SAMARITAN HOSPITAL presents extra inducements to Invalids throughout the State as a safe and quiet asylum in any case of protracted illness, or in cases, more particularly, requiring Surgical Operation, where some stay is necessary in after treatment. Rooms vary in price, according to the character of appointments necessary and service required, ranging, " general terms, between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand of service. gas-Address, SISTER ANTHONY, Hospital of the Good Samaritan, Corner of Stacth and Lock Ste., Otºtoºººººº- Ohio. WILson BRD's. M A R K TVA IN'S S HIRT S Made to order of N. Y. M. Muslin and 2300 HEAVY Linen, per dozen - - - $36 00 Wamsutta Muslin and 2100 HEAVY Lin- en, per dozen - - - - - - - - 33.00 Wamsutta Muslin and 1900 Linen, per doz. 30.00 Lonsdale Muslin and 1700 Linen, per doz. 27.00 First three qualities have ALL LIN EN Cuffs and Neckbands. At above prices Cuffs are attached. Same quality of our own manufac- ture, ready-made, $3 per dozen less. Perfect satisfaction given or money cheerfully refunded. Also import and Manufacture Men’s Furnish- ing Goods. Pike's Opera-House, Fourth Street, Cincinnati; 931 Wabash Avenue, and 88 West Washington Street, Chicago. CALMA R.G.O. MANUFACTURING COMPANY., MANUFACTURERS AND IMPORTERS OF AND Window Shades, 67 WºSzº Motºziz Szºzºz', CINCINNXTI, O, H. H. BRENEMAN, Proprietor, NEW E O O. Ex. IS NOVV READY FOR CA NVASSERS. It contains over 600 pages of reading matter, with 250 engravings, designed expressly for this work, by the best artists in the country. Agents now at work upon, it are meeting with unparalleled success. Agents at Circleville, O., reports 25 orders in 2 days; one at Louisville, Ky., reports 175 orders in 8 days; one at Middletown, Conn., reports 200 orders in 12 days; one at Cincinnati, O., re. ports 250 in 12 days. Early applicants secure choice of territory. For circulars, terms, &c., address NETTLETON & CO., 161 Elm Street, Cincinnati, O. BASCOM & CARPENTER, Stationers, Printer -AND- • * : *** Blank Book Manufacturers, 136 VINE sº CEREET, &\\\\\\\\\e E. D. ALBRO & BRO. IMPORTERS AND MANUFACTURESRS OF FOREIGN and DOMESTIC WOODS In Veneers, Boards and Plank, frºnt-Miº','!-Birčani al-Bilº, The only house in the Western country that saws Spanish and Mexie C8-T1 §.º. Cigar-Box Makers. We . ºw" wood direct, and ll at prices to compete with any and everybody, - *. º keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. office and Warerooms, 136 and 138 West Second Street, Veneer Mill, 507, 509, 511, 513 & 515 W. Sixth St., CINCIMNAT1- *... -- Wm. Wilson McGrew, * wo. zz masr Fovara sºrrºr. f PIP3E'S OPERA, HOUSE BUILDING, Importer and Dealer Diamond and Gold Jewelry, watches for Ladies and Gentlemen, Sterling Silver Tableware, Bronzes, Antique and Modern; Marble and Bronze Clocks, Marble Statuary, FAN cy. Coons, G E N E R A LLY. f Rºº | Fº . -> f W ſº - [… º M º: - i. - *~s & - sº º tº ºr tº ºr -º-º: $2. ſº. Tº \ }, \ \º Nº. . . . tº: º º ºvs " . “, ºr ºs .."º. r . ſ * g - º * . . . - s & º: º: | º fift. kº º i º - ---. º ||{{\ º - º ------ *- º Nº. º, sº º * tº . i: sº. |; tº, |..; ſº } º | | # É - § 5. - i." §: |º [2:SE2S. |†† CINCINN ATI. E" A C TU T., T Y. J A M E S G FR A H A M, M. D., D E A N, Professor of the Theory and I?ractice of Medicine and Clinical Medicine. ROBERTS BARTHOLOW, M. D., W. W. DAWSON, M.D., Professor of Materia Medica and Therapeutics. Professor of Principles and Practice of Surgery and Clinical Surgery W. H. GOBRECHT, M.D., C. D. PALMER, M.D., Professor of Anatomy. Professor of Medical and Surgical Diseases of Women. P. S. CONNER, M.D., T. A. REAMY, M.D., I’rofessor of Surgical Anatomy. Professor of Obstetrics and Diseases of Children. W. W. SEELY, M.D., JOHN L. CLEVELAND, M.D., Professor of Diseases of the Eye and Ear. Lemonstrator of Anatomy. SAMUEL NICKLES, M. D., CHARLES KEARNS, M.D., Professor of Physics and Medical Chemistry Assistant to the Chair of Surgery. J. A. M. E S T . W H ITT Al IX E R , Professor of Physiology and Secretary of the Faculty. *~ T. Louis BBown, Prosector of Anatomy. Janitor, College Building, Sixth St., bet. Vine and Rae, - Printed and Published by Noah is & M URBY, Medical College of Ohio Building, Cincinnati, HE CLINIC, PluſBLISHED EVERY SATURDAY. TER MS-$2.00 a Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editor: All Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer. Vol. 2. C IN C IN N A TI, A PRIL 6, 1872. No. 14. JAS. T. VVHITTAKER, M. D. No. 101 West Ninth Street, Cincinnati. _ASSOCIALTE EIDITOR,S. W. W. D.Awson, M. D. THAD. A. REAMY, M. D. P. S. ConnKR, M. D. C. D. PALMER, M. D. W. W. Sārīy, M. D. SAMUEL NIGKLEs, M. D. CHAs. KEARNs, M. D. JNo. L. CLEvELAND, M. D. RoBERTs BARTHoLow, M. D. w. W. SEELY, M. D., . No. 118 West.Seventh Street, Cincinnati. —A F.TRT-Tº * C L U B R A TES, *-*. Editor. º •º *º TREAsuaza. co-Ary we ces Fashionable Hatters, IMPORTERS AND MANUFACTURERS OF FºES” FöRS, 92 wrisT FOURTH ST. Opposite Post Office, * :**** ‘. . . CINCININATI. 12 & 6 & & sº lºav"Special Inducements to Medical Men. C O N T E N T S. - == —, Page. §§§liºn ORIGINALL ARTICLES The Mode of Production and the Treatment of Nervous Diseases by Prof. C. E. Brown-Séquard M. D., F. R. S I57 * TRANSLATION The Process of Decomposition (An Abstract from Caspar's Gerichtl. Medicin. Berlin 1871) T 60 SCIENTIFIC NOTES Sea Sickness, the Means of Relieving it—Sympathetic Ophthalmia...160 ME DIGALL NEWS. The “Milah” and the “Mohel”—The Significance of Diagnosis—A Vaccination Martyr-The Libéral{Party in Prussia–Trepan- ning the Sternum—A Knighthood for Cormack—A Cross for Virchow s • * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * ee e s - e is e e s - e. e. e. a CLINICAL MEMORANIDA Constriction of the Penis by a Wedding Ring—Hernia Reduced by Digital Dilitation—The Chlorohydrate of Narceine—Treatment of Enuresis—Electricity in Trachoma—Xylol in Small-Pox 1ſ;8 * * * * * * * -º-sº ºn wºº -- * - * * We are put in possession, now, of all the facts beating upon the much vexed and perplexed reflex action by the distinguished author of this doctrine himself. A full abstract of the chapter from Caspar's “Legal Medicine” on the process of decomposition follows. A perusal of this chapter in any other work on medical% jurisprudence will exhibit how great was our need of more positive and definite information on this subject. Some of us at least, can confirm by personal expe- -rience the value of the expedient suggested in relief of sea-sickness whether we subscribe to the theory in ex- planation ºf not. We have an entertaining letter to-day with some ed- 120 º ERS AN | - *: J. TAFT, Editor Dental Register J. & W. TAFT, TXTENTISTS 117 WEST FOURTH STREET, CHN CIN N ATI, O. A Monthly Journal, CONTAINING 48 PAGES, tailed information as to exactly how it is done in Israel. *~~ Devoted to the Interests of the Dental Profession, List of Pharmaceutical Preparations, Jonºv wrºzºn dº anoznan, FIFILADELPHIA. —dº- ELIX. PHOS, IRON, QUININE AND STRYCHNIA, ELIXIR OF GENTIAN FERRATED, ELIXIR, WALERIANATE OF AMMONIA, (Goddard’s Formula,) ELIXIR. 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CAM'ſ A.I.R.G.O MANUFACTURING COMPANY., MANUFACTURERS AND IMPORTERS OF Window Shades, &? Wasr Fovarw Szºzº, CINCINNXT, O, B. H. BRENEMAN, Proprietor. M A F P& T VVA. I. N'S NEW E O O. Ex IS NOVV READY FOR CA N VASSE FRS. It contains over 600 pages of read ng matter, with 250 engravings, designed expressly for this work, by the best artists in the country. Agents now at work upon, it are meeting with unparalleled success. Agents at Circleville, O., reports 25 orders in 2 days; one at Louisville, Ky., reports 175 orders in 8 days; one at Middletown, Conn., reports 200 orders in 12 days; one at Cincinnati, O., re- ports 250 in 12 days. Early applicants secure choice of territory. For circulars, terms, &c., address NETTLETON & CO., 161 Elm Street, Cincinnati, O. *A BASCOM & CARPENTER, Stationers, Printers * Blank Book Manufacturers, 136 VINE sºl{REET, &NWASNN\\\\e E. De ALBIRO & BRO. 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Special attention paid to orders for Fine Microscopic Objects and Microscopic Apparatus, Magnifiers and Readers in great varietv. Medical Batteries, Barometers, Thermo- meters, Hygrometers, Urinometers and Rainn Gauges, of the most approved construction always on hand. All orders promptly and accurately filled. JAS. FOSTER, JR. F. S. SHACKLEFORD, } * * JAs. FostER, JR. & Co. S. W. Cor. Fifth & Race Sts., Cincinnati, 0. TXTER, S.INT. TN/I_A_TEv/SIET’S º E-F º º gºº A "&"º 3º) TRUSSES. & 9. No. 758 BROADwAY, NEW YORR HAVE been in the habit of applying and recommending the Truss manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- I clusion of all others, and have found it to give general satisfaction, effect ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined. LEWIS A. SAYRE, M. D. Surgeon, Bellevue Hospital. From Prof. Willard Parker to S. D. Townsend, M. D., Surgeon to the Massachusetts General Hospital. B EG leave to state for the benefit of all concerned, that I have knowr 1Jr. S. N. Marsh the last fifteen years. * * I am in the constant habit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with any of the risks to the patient that exist in many of the plans suggested and attempted to be carried into execution. I have confidence in Dr. Marsh as a gentleman of homoſ and integrity, and as such recommend him to the members of the modi. cal profession generally. WILLARD PARKER, M. D. Professor of Surgery, New York City Dr. S. N. Marsh's Patent Radical Cure Truss and all other kinds of Trusses, Shoulder Braces, Supporters, Elastic Stockings, SuspenBory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radica) Cure Trugs Offices of S. N. MARSH & CO., No. 2 Vesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. OPPOSITE THE HIGH STEEPLE, mar Agents for Clement's Patent Artificial Legs. & Co., IT. THD. Suire wholesale DRuggists, IM. A. IN U E A CT Uſ ER, IIST G. £Hexists AND PHARMACEutists, CINCINNATI, OHIO. Have constantly on hand a full assortment of s}ºx,xecºexex, OX3 UGS ANYO IV.OEO)(c)(N)es, cºeryxxcAx. 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The long standing and well and widely known repu- :ation of our house we offer as a guarantee for the reliability of our preparation, and the quality of the goods sold by us generally. TIH. H. cI.INTI c. 157 [No. 14. Vol. 2..] S A T U-R D A Y, A P R I L 6, 1872. O R. I. G. I. N. A. L. A. R. TI C L E S. T H II E MO DE OF ORIGIN AND THIE TREATMENT O F NERVOLUS DISEASES. BY PROF. C. E. Brown-SEQUARD, M. D., F. R. S. Prof. of Comparative and Experimental Pathology (Paris), A Lecture Delivered at the Cincinnati Hospital, March 28, '72. Gentlemen and Ladies: In my lecture ten or twelve days ago, I dwelt upon the modes of production of certain brain diseases. I at- tempted to show you that the views of former belief can now be held no longer. The proofs I brought forward are perfectly convincing of this fact and I do not intend to return to speak of them again to-day. There is one point, however, in the mode of the production of brain disease which my limited time did not permit me to fully explain, and I wish to speak of this before I take up the subject for to-day. Those present at my last lecture will remember that I said that symptoms arise not as the direct but as an indirect effect, an influence originating at a distance and propagated to other parts so as to disturb their functions. I stated that there were two sets of phenom- ena produced at a distance from the seat of irritation. These two effects are absolutely distinct from each other. The one consists in the production of morbid phenomena, the other in the induction of a cessation of activity giv- ing rise to paralytic symptoms. Take the case of an individual struck on the left side of the head. There may ensue the loss of the power of expressing his ideas by speech. In this case there is an arrest, an interrup- tion or a stoppage of activity. If the same individual under other circumstances happen to be struck in the same part there might other symptoms manifest quite different in character, as epilepsy, for instance. In this case, I remarked, there would be the production of mor- bid phenomena. There are, thus, these two great classes of symptoms from the same lesion, the arrest of activity on the one hand and the production of morbid phenom- ena on the other. There are many other ways to ex- plain the production of these symptoms besides the one to be mentioned. The view that the function of that part of the nervous system in which disease exists, is lost or destroyed, is false. Pressure, for instance, exerted upon a part may produce a set of symptoms or may in- duce a cessation of activity of various faculties of the mind. I do not here by any means intend to say that destruction of a part is not followed by certain symp- toms, only that it is not followed by the same symptoms. Dr. Tuerck, a physician of Vienna, was the first to point out a fact to which some friends of mine, Charcot and Vulpian and others contributed largely. It is that when disease exists in certain parts its propagation is along the nerve fibres extending from it. Thus, disease may reach the extremity of the body from the head to the foot. In that case an active disorganization of some fibres in their entire length takes place. This secondary degeneration occurs very frequently. It is certainly to be looked upon as a cause of symptoms, but can not be regarded as the principal cause for the very manifest reason that these symptoms only appear after a long time, one month or more being required sometimes from the head to the foot, or arm, or from the liver to the brain, etc. So that we are not to look upon symptoms that appear immediately as caused in that way. In most instances, symptoms of brain disease arise by a mechanism entirely different. There are many ways in which they can be explained but their explanation requires such a knowledge of physiology and pathology that I can not enter into them now. &r It is perfectly well known that the nervous system can act upon parts so as to affect their blood supply, to produce in them a diminution of their blood. But this view although it has no share in the production of brain symptoms can not explain more than a few phenomena. It is now perfectly well known, and I have contributed to its establishment, that an irritation starting from dis- ease in the tissue of the brain or spinal cord may pro- duce an attraction of blood to, or increase in its amount in, many other parts. This is by a peculiar chemical influence exerted on the tissue so that blood is attracted to it and its nutrition is increased. Indeed inflamma- tion may be so produced. Many of the inflammations of the lungs and other viscera of the chest are brought about by this mechanism. But this is not the legitimate way. The general mode of production of symptoms is simply by the arrest of activity in certain parts. We know, now, well that certain cells of gray matter may be so acted upon that their action will be stopped just as a piece of soft iron is stopped by a magnet. It is a matter of indifference by what means this arrest of ac- tivity is produced. It is only essential that we recog- nise that any function may be arrested by distant irritation, When we take an animal and prick quickly certain parts of the cord or medulla oblongata, even by a mere prick Scarcely below the surface with the thinnest needle, we find very frequently that the action of those cells which serve for mentality in man as well as in an- imals ceases. They become unconscious for a time, sometimes permanently. Besides the cessation of the activity of the cells of mental action there may be an arrest of activity of the cells serving to respiration and besides' the arrest of 158 [APR. 6, 1872. TIH. H. C.LINTI c. activity of the cells of the nervous system there may be an arrest of the activity of the cells which serve for the interchange between the blood and the tissues so that the blood remains red in the veins. In health the blood becomes black because it surrenders its oxygen to the tissues and takes up carbonic acid gas. In dis- ease there is an arrest of the activity of the cells of the tissues so that this interchange does not take place and the color of the blood remains unchanged. In many in- stances also there is a diminution in the force of the cir- culation so far as it depends upon the heart. There are other manifestations of like interest regarding this sub- ject but I have no time to dwell upon them now. I may mention merely the phenomena of the arrest of putrefaction. In one case a dog exhibited no signs of putrefaction in two or three weeks and muscles have been preserved as long as seven or eight weeks, facts which go to show how great an influence is exerted by a mere prick of the needle. If we consider the greatness of the effects from such a trifling cause we observe that we have results that are similar to those from severe lesions as hemorrhage from the brain. Death even will occur very frequently. But it is not death which I am to consider but symptoms. In cases of sudden alterations at the base of the brain we have symptoms such as paralysis produced suddenly. In some cases it disappears, also, suddenly, though the cause may be continous. I have collected, now, more than fifty cases of disease of the base of the brain at the level of the crura cerebelli and in the neghborhood of the pons Varolii and corpora restiformia in which there was paralysis on the side of the body corresponding with the disease. These cases cannot possibly be explained by the conduction of nerve fibres. They are only explicable by the indirect influence of distant points of irritation. - To the medical gentlemen here present I will say that of the fifty cases of same-sided lesion and paralysis— cases not all seen by myself but collected from reliable sources—that when the lesion is deeper, when it en- croaches upon the tissue to such extent as to destroy one-half of its substance, the mechanism of the produc- tion of symptoms may appear to be different. A lasting paralysis may ensue upon an irritation con- fined to the nerves of one side of the chest. A paralysis of the corresponding side thus may be of weeks duration even of months. Dr. August Waller who assisted in the examination of these cases showed that these nerves were in no connection with the paralysed limbs. The paralysis so induced is by an indirect influence, that is, an irritation originating at one point induces these phenomena at a distant point. If we take other facts, such as those that occur in animals after division of one nerve only, as the sciatic, we find many different symptoms, indeed, from the same lesion. A great variety of effects is thus induced which may persist for months and months. In certain animals we notice an increase in the temperature of the ear. Sensibility to pinching, burns and great irritation diminishes: later new symptoms appear, epilepsy may manifest and still later, changes occur in the skin, the hair may fall or parasites may be found in places pre- viously free, facts showing the alteration which has taken place. When the hair has all fallen, the fits cease, sensibility to pain returns, the animal has recovered. Other interesting facts in this connection are the in- crease in milk in the mammary gland in the female animal on the side corresponding to the lesion, the limb in which the nerve has been divided has increased in sensibility, the belly hangs loose and paralysis may ensue. There are many other facts that might be men- tioned but enough has been stated to show the prop- agation of irritation to distant points. If we pass to another series of proofs in man as well as in the lower animals resting upon experiments of injuring the auditory nerve, a nerve of special sense, we observe here again that a great variety of effects will be produced. I may only mention them briefly; cold, toppling gait but full possession of the mind and in gome cases, without irritation of the skin, great sensi- bility to pain. In the case of a large bull-frog which I experimented upon first in this country pricking the bag which contains it caused the most different effects. When the nerve on the opposite side was injured the animal moved in a circle like a horse in a circus. After a while it regains the power of going straight showing that this effect is only temporary. Another phenomena of interest was the hyperaesthesia observed everywhere. In the case of the frog on one occasion the animal gave vent to an audible sound of pain, a phenomenon of most rare occurrence. These are all direct proofs that an irritation will give rise to the most diverse effects. I was once called to see a patient in great suffering who had symptoms of an abscess in the mastoid portion of the temporal bone with irritation of the auditory nerve. An opening into the mastoid process and the discharge of the abscess relieved him. In children not infre- quently convulsions are due to an irritation of the auditory nerve. This has been shown to be true by a medical friend of mine in London. And now I must pass to other considerations discon- nected with this part of my subject. I should like to be able to speak further upon the phenomena dependent upon an excitation or arrest of nervous activity but I am warned by my limited time to enter upon the second part of my programme as announced. I am now to speak of the mode of treatment more especially of functional nervous disorders. It is quite essential that we still hold in view this phenomena of arrest of activity in considering the treatment of nervous disorders. It is in this way that convulsions are checked. I have already remarked in the Academy of Medicine how convulsions are checked by peripheric irritation some in one place, others in another. Even the most violent and lasting convulsions, those of half an hour's duration, those in wnich violent jerking follows, APR. 6, 1872.] T H E CI, IISTI c. 159 as after strychnia, may be arrested by pulling the big toe, etc. It is in this way that we stop the action of the cord and complete relaxation follows. In epilepsy we may have the opportunity in the use of these means to detect cases of feigned affection. It is not necessary that pricking be resorted to, galvanisation or any irrita- tion may be sufficient to check the paroxysm. More than this, all kinds of convulsion may be checked in this way and, what sounds strange, by the same means as those which produced them. My friend Bernard found that when chloroform was applied to the frog, circulation in the capillaries ceased. Bernard did not explain this but it is certainly due to reflex action, the bloodvessels are acted upon just as after galvanisation of certain nerves. In one woman in whom a recurrence of the paroxysm was especially to be dreaded, as she had fractured the humerus and dislocated the shoulder by the mere force of muscular effort in the last attack, I administered chloroform and kept her under it continuously for a number of days. Hibbardon of London, kept a patient under chloroform three days permitting her to recover only sufficiently to take liquid food. This might seem a dangerous practice, but Simp- son has found that patients may be kept under chloro- form for many days. I was not aware of this fact at the time but have since ascertained it. If no vomiting nor depression of pulse occurs, chloroform may be adminis- tered with impunity for a long time. In my case the patient passed over the threatened attacks safely and was afterwards free for a fortnight when another convul- sion occurred. Callus had already formed, however, so that there was no further damage. - You will ask why is it not legitimate to employ chlor- oform in every case. It is a practice I would not hesitate to adopt in every case where I could administer it my. || self. Unfortunately the physician is so busy—having more than one case to attend to, at least after a certain age—that he has not the time to so employ it. But there are cases in which epilepsy is followed by coma or dangerous hemorrhage or threatening suffocation from spasm of the larynx in which the physician is not to hesitate but is to give it a whole day at a time. In my practice I have not had more than eight or ten such cases, and I have always succeeded in shortening the fit and the coma, in some instances when the coma had lasted previously from one to three days. Chloroform produces these effects in these cases by reflex action. There are many cases of nervous affection in which a peripheric irritation effects a cure or at least a preven- tion of the disease. What, now, are the best means to be employed? In organic disease of the base of the brain or in any part of the brain or cord the most powerful means of changing the state of the circulation is the heated iron. In all applications pain is to be avoided. If I had again to treat the eminent patient who was under my care in Paris in '57 I would not again use the six moxas of Previous employment. Moxas indeed are to be rejected altogether as pain is really an obstacle to cure. Of all means the actual cautery brought to a white heat and applied in parallel lines upon the surface is the best, least painful, and most potent counter-irritant. The great mistake, by which this remedy of old employ- ment in England and here was brought into disrepute, consisted in the application of the iron at a red heat when the pain induced is very severe Heated to white- ness it not only gives less pain but the resulting eschar heals more rapidly. I may say here that physicians in the rule are too yielding to the feelings of their patients. They are not bold enough in this regard dreading to be called barbarians. It is unfortunate that there is a tendency towards the abandonment of this agency as its pain is hardly felt and its after effects are of very short duration. I have myself used the heated iron in almost all cases of nervous affection. I have applied it freely even to the faces of young ladies who have then gone out among their friends flattered with the belief that they had exhibited an astonishing courage in withstand- ing it. Permanent disfiguration is very rare, the mark generally disappears in 3-5 weeks and the full beauty of the skin returns. It should be passed over the surface with some pressure and with speed in parallel lines. It hardly produces any pain only a sensation of dryness. The resulting eschar has but very little discharge and soon disappears. This means is best adapted to cases in which there is congestion somewhere. It is not neces- sary, however, that there shall be congestion as it is the best means of treatment of simple neuralgia where there is no congestion. I have now in memory but very few cases that have resisted it. Jobert and Valleix say they have never seen it fail. I do'nt go so far as that. I have had failures. Another means extremely potential is ice. This agent ranks next to the actual cautery. It is to be ap- plied, not by Chapman's ice bag, but bare or crushed finely and folded in a towel. It is not to remain upon the surface more than 10 or 12 minutes. In any kind of nervous affection it offers a good chance of cure. It looses its efficacy, however, after a time. The idea was put forth that ice diminished the temperature of the brain by reducing the size of the blood-vessels. I doubt if it do not rather dilate the vessels as after galvanisation of the nerve in the neck. After this my friend Dr. Waller a celebrated German physician, untimely dead, as he had published very little, conceived the idea that he could produce changes in nutrition in the head by pressing upon the nerves in the neck. Many physicians had had this idea before but they thought the changes were effected by pressure upon the carotid. Now it is known that they depend upon pressure of the par vagum and sympathetic. When it was found that we could produce changes in the blood vessels by pressure upon these nerves I one day tried the influence of galvanism. Of course I was unaware of the great risks of such a proceedure. We went on boldly with the intention of stopping a terrible 160 [APR. 6, 1872. TIEEE c1.TISTI c. —r- head-ache. Well, we stopped the head-ache but we almost stopped life too. The patient became pulseless and lost consciousness for two or three minntes. It proved a rather dangerous remedy and we did not re- apply it. The method of Waller was to press upon the nerves near the angle of the jaw, that is, over the carotid and whenever the carotid is pressed, the nerves are also pressed. The result of my experiment made me un- willing to employ this means. My friend Dr. Waller used to relieve epilepsy in this way on a large scale. He used it with great advantage in cases of disease of the cells of gray matter of the brain. In this way also in that group of affections in which we desire to bring. about a diminution of the force and frequency of the heart's action, as in the acute fever of articular rheu- matism, this means may be employed with benefit. As my time is now becoming short I shall content myself with the remark that if we keep in view the dis- coveries and teachings of the last ten years regarding the suspension of activity by peripheric irritation we shall he led to a better mode of treatment of nervous affections. I should say something with reference to the points of election in making this irritation. If we act on a sur- face which receives nerves from a centre we act upon the centre itself; thus in epilepsy as the disease usually affects the medulla oblongata we select parts in connec- tion with nerves from this centre. In cases of congestion of the spine we select the skin of the leg or thigh. These facts have been very little known or developed. Lastly we are to remember to avoid pain as a coun- ter-irritant as pain interferes with the desired effect. A good agent in this regard is the nitrate of silver whose application is void of pain. It possesses great power in neuralgias and other nervous affections. It rapidly changes the color of the skin to a dark chestnut color but it produces no sensation. Collodion applied to a large surface or oil answers pretty much the same pur- pose as a means of peripheric irritation of the nerves of the skin though their action is not perceived. In some cases of inflammation of the throat such simple means as these afford excellent results. I should be glad to continue this subject further but I have already passed the limits of my time. I have in conclusion to thank you, ladies and gentlemen, for your kind attention. —sº-O-ºsm- A SUIT FOR FORGERY.—At a late meeting of the British General Medical Council (Mar. 1, ’72,), Dr. Ben- nett moved, Dr. Aquilla Smith seconded him, and it was resolved: “That the Registrar be directed to write to the Solicitor authorising him to take the necessary steps to prosecute the student alleged to have been guilty of forging a certificate of having passed his preliminary examination at the Hall of the Society of Apothecaries, by which he obtained admission on the Students' Reg- ister.” T H E PR o o Ess o F D Eco M P os IT I o N. An Abstract from Caspar's Handbuch der Gerichtlichen Medicin. Berlin, 1871. sº. In No. 10 of “THE CLINIC” we endeavored to lay before its readers, concisely, the views of Caspar on the signs of death, as developed in his exhaustive work on medical jurisprudence, leaving the consideration of the process of decomposition, with reference to the time of death, for a separate article. We will now turn our attention to this subject. Caspar says it is surrounded with many difficulties. It is not easy to describe, by mere words, the various changes in color and consistency of organs which the corpse undergoes, and in view of the many agents that affect the process of decomposition anything like a general rule can be laid down only with great caution. He thinks it is scarcely an exaggeration when Orfila says that “it is beyond the powers of man,” to determine the time of death in corpses that have undergone decomposition. And yet, Devergie says of his subordinates in the Paris Morgue, and Caspar has noticed the fact himself in Berlin, that men without any culture whatever, acquire, by mere routine, a judgment in this matter, which, in general, is quite correct; whence our author argues it must be possible to do it still more accurately by employing scientific means. Whilst appreciatings the labors of Orfila, Lesueur, Güntz and Devergie”, he censures them for devoting too much attention to trifling details, making their works prac- tically worthless for the medical jurist. Interior Conditions of Decomposition. The causes which modify the process of decomposition, by either hastening or retarding it, so that the corpse of A may in from 24 to 36 hours present the same appear- ance as the corpse of B in from 3 to 4 weeks, must be sought in the individual, or externally. As a matter of course, decomposition itself is possible only through ex- terior influences. Fresh flesh, hermetically sealed, does not decompose. Individually, the progress of decomposition is mod- ified, 1. By Age. Caspar admits what all authors main- tain, that neo-nati, cet, par., undergo decomposition more rapidly than other corpses. Still, we have to take into consideration the fact not noticed by any other writer, that they are nearly all found naked immedi- ately after birth, or at most, enveloped in a few rags, having been exposed, or thrown into the water, into vaults, or hidden in manure or rubbish; whilst naked corpses of a greater age are almost exclusively only * Orfila (). Ilesuer, Handb. z. , Gebr. f. Gerichtl. Leipzig, 1832-35. Güntz, der Leichnam des Nengeborenen, Leipzig, 1827. Devergie I, p. 88-253, Ausgrabungen, APR. 6, 1872.] TIH. H. cIIISTI c. 161 those of persons drowned. But the influence of clothing on retarding the process of decomposition is very essential. 2. Sea, according to Caspar, has no influence. But he has noticed that the corpses of women, who died immediately after parturition, decomposed very rapidly, no matter what was the cause of death. - 3. The Constitution has a very decided influence. Fat, spongy and lymphatic bodies undergo decomposi- tion far more rapidly than bodies lean and dry, because an abundance of liquids favors the process. In the corpses of the aged this process is retarded, probably, because they are generally lean and dry. 4. The mode of death has a marked effect on the pro- cess of decomposition. It occurs much later after the sudden death of healthy persons than in persons dead of diseases which exhaust the system ; such as typhus, dropsy following organic lesions, or tuberculosis. Mutilated bodies, and those of persons killed by repeated acts of violence, by mechanical force, on railroads, etc., decompose rapidly. Excepted from this rule are the bodies of persons that were killed by the falling of walls; the stones, rubbish, or sand with which they re- main covered, preventing a direct contact with the air. Persons suffocated by smoke, . carbonic oxide gas, or sulphuretted hydrogen, decompose rapidly. After death from narcotic poisons, decomposition is accelerated. This is much less the case after other poisons, and especially phosphorus. Where the blood was poisoned by alcohol, i. e., in cases of drunkards who died of apoplexy, in a state of intoxication, Caspar observed that the corpses retained their freshness for a remark- ably long time. - It is worthy of notice, finally, that after poisoning by sulphuric acid the process of decomposition is decidedly retarded, probably because the acid prevents the forma- tion of ammonia, or continues to neutralise the ammonia formed by decomposition. After poisoning by arsenic decomposition occurs according to the ordinary laws, but it is well known thºt it is interrupted in its course by the process of mummification, of which more here- after. # - We ought to remember, however, that, although the foregoing statements are generally correct, there must be still other causes, as yet unknown, which hasten or retard decomposition. • As cases in point, the following are cited by Caspar. On March 18th, 1848, two men suffered the same death, by º wounds, at the same time on the barricades in Berlin. Nevertheless, the signs of decomposition were dissimilar. At another time, a man and a woman, both aged between 50 and 60 years, died the same night from suffocation by carbonic oxide gas. Four days after, the man's corpse was quite green on the abdomen and back, whilst that of the woman, though remarkably fat, was, internally as well as externally, quite fresh. Eacterior Conditions of Decomposition. The exterior conditions have a more decided effect on decomposition than the interior. They are air, water and heat. - a. Atmospherie air. Everything that favros or hinders its access to dead animal (as well as vegetable) sub- stances, hastens or retards the process of decomposition. Helmholz” has shown that no decomposition takes place in flesh that is in contact with water cleared by boiling and air conducted through red-hot tubes, until all | organic germs are destroyed. The oxygea of the atmos- pheric air is, consequently, the chief condition of de- composition. Corpses remaining in the open air decom- pose much more rapidly than those that were buried, and even than those lying in water. Decomposition sets in sooner in naked or lightly clothed corpses than in those that are completely dressed, especially if the clothes are tight and but little permeable. The access of air may be obstructed or favored by the composition of the earth. If it is light and porous, de- composition will commence sooner than if it is moist and dense. But here a great deal must be ascribed to the action of water because light earth (sand) is at the same time dry, whilst moist earth (clay) is naturally damp. So, too, corpses decompose sooner in shallow graves than in those of great depth. It is further im- portant to consider the cover that surrounds the corpses is the earth, which is well shown by Orfila. Everybody knows how soon coffins of common pine are destroyed, and, with them, the corpses; whilst the great men of of former times, buried in coffins of hard wood, tin or stone, were preserved for an uncommonly long period. On the contrary, corpses that were buried in an entirely nude state decompose very rapidly. b. Water. Without water and watery vapor no de- composition takes place. But the water of the corpse itself is sufficient. It gradually evaporates, and, event- ually, bursts the walls of the abdomen, of the thorax and, finally, even the bones of the skull, and the corpse macerates in its own liquids. Before this time, however, maggots and larvae make their appearance on the surface at first on the eyelids, ears, vulva and groins, until their number is increased to myriads and the complete and total destruction of all the soft parts follows. But in proportion as water without has access to the corpse, decomposition will be more rapid, and vice versa. c. Heat. A high degree of heat, alone, causes the liquids of the body to evaporate and favors the very op. posite of the process of decomposition, i.e., the drying up, if not roasting of the corpse, as we see it in com- bustion. Ordinary heat, however, when combined with air and humidity, favors decomposition. It is well known that a corpse will decompose more rapidly in summer than in winter. Bodies that at a summer tem- perature of 16 to 20° R. are still in a good state of pre- servation, may, in the course of 24 hours, become en- tirely unfit for dissection, whilst in water, at a tempera- ature of from 5 to 8° R. this will not be the case for 10 or 12 days. The difference of temperature is exceed- ingly remarkable in the case of water. If the corpse freezes in water (or humid earth) it will be preserrved *Erdmann d. Marchner, Journal d. Pract. Chemi., Bd. 31, s.420. 162 [APR. 6, 1872. TIEEE IEH C T LI INTIL C. by the mammoth, exhumed in Siberia, and now to be seen in the Museum of the University at Moscow, though the remains of the tissues are partly saponified. In winter, a corpse taken from water showing a tempera- ture of from 2 to 6°. R. 10 to 12 days after death, may still be so well preserved as to enable an examiner to demonstrate the signs of death from suffocation, which in summer, at a temperature of from 18 to 20° R. is often impossible after 5 to 7 days; and here, another circumstance must be considered. It is well known, that the temperature of the water is lower, under its surface, than on it and in the superior strata, because the rays of the sun strike only these. Decomposition will, therefore, be accelerated when the corpse is on the surface, and retarded when it remained at the bottom. Another point that must not be overlooked is this, that a corpse taken from the water and exposed to the air, will decompose with exceeding rapidity. The progress will be greater in one day than it would have been in 3 or 4 days, had the corpse remained in the water. So, too, a higher or lower degree of the temperature of the earth affects decomposition. Corpses buried in shallow graves will, therefore, (as also for the reason given above under atmospheric air) decompose more rapidly than those in deep graves, Comparison of the Signs of Decomposition according to the Media, Caspar says it is perplexing for the practitioner to di- vide the process of decomposition into stages according to the different media, as has been done by Orfila, De- vergie and Güntz, and he thinks it is superfluous, be- cause this process is, in all cases, one and the same from the first moment to the last, modified only by the media and all the various conditions heretofore enumerated. It appears, to him, more judicious to set up a general criterion regarding all three media, i.e., air, water and earth, leaving the effect of the other conditions to be considered in each given case. Aware of the difficulty of setting up such criterion, yet from his large experience he does not believe to depart from the truth in announc- ing the following doctrine: the average degree of temper- ature being about equal, a corpse eago&cd to the open air for one week (or month), exhibits the same degree of decom- position as a corpse that remained in water two weeks (or months) amd one that was buried in the earth in the usual way, for eight weeks (or months). The same degree of decomposition will therefore, cet. par., be shown by three corpses of which a has been exposed to the air, e. g., on the ground, for a month; b was drowned two months ago; and c has been dead and buried in an ordinary coffin for eight months. A due regard for this rule and a proper intimation of the circumstances of each specific case, will avoid essential €rrorS. for a long time, even for thousands of years, as is shown | Successive Changes of the Corpse, Externally. 1. The first sign is the well known greenish color of the walls of the abdomen, on the appearance of which the odor of decomposition is noticed. It occurs in from 24 to 36 hours. (The exception in the case of persons found drowned will be referred to hereafter). • 2. In the same time, the eye-balls soften, and yield to the pressure of the finger. . • . 3. In from 3 to 5 days after death this green color becomes more marked and covers the entire abdomen, including the exterior sexual organs. In the latter, it assumes, in both sexes, a rather brownish-green, dirty appearance from the start. In a great many corpses, especially in cases of suffocation, sanguineous, frothy liquids, with air-bubbles, ooze from nostrils and mouth. At the same time, green spots appear, with great topical irregularity, on other places, especially on the back, the lower extremities, the neck and lateral portions of the thorax. - 4. In from 8 to 12 days after death this discoloration, with which the odor keeps even pace, has covered the entire body and become darker. In Some places, especially in the face and on the entire neck down to the breast, the color even at this stage, is reddish-green, the decomposed blood having extravasated into the cellular tissue. Putrid gases are developed and inflate the abdomen. These are (but not in all cases) combustible gases, sulphurretted and phosphuretted hydrogen. On making an incision in the walls of the abdomen, the gas which escapes, will, on lighting it, burn for a considera- ble time, with a small flame. This takes place, almost without exception, with the gas proceeding from the scrotum. The cornea has become concave, but the color of the eyes may still be recognized, whilst it is no longer possible, in all cases, to determine whether the pupils of the immature foetus are open or not. The sphincter ani is open. In some places of the corpse, especially on the extremities, on the neck and breast, cutaneous veins of a dirty red may be seen through patches of skin of a lighter color. The nails are still firm. 5. In from 14 to 20 days after death, the color of decom- position has everywhere become green, like the color of the frog, and bloodred-brown. The cuticle, in some places, is raised in blisters of the size of a walnut ; in others, patches as large as a plate, and still larger, are entirely detached. Innumerable maggots cover the body, seeking especially the folds of the skin and the natural cavities. The evolution of gas has increased to such an extent, that the abdomen looks like a large ball, the thorax is artificially rasied, and the entire cellular tissue presents the appearance of inflation. The corpse resembles that of a giant. The features can no longer be distinguished, and even intimate friends find it difficult to recognize the body; for the lids, the lips, the nose and the cheeks appearing much swelled, the physiognomy is naturally entirely different. The color APR. 6, 1872.] T H. H. C. T., T N T C . 163 of the eyes can no longer be distinguished, because the eye-ball (iris and pupil being obliterated) shows in all such corpses, without exception, a uniform dirty-red color in the entire extent of the sclerotica. In men, the penis has become enormously large, and the scrotum may reach the size of a child’s head. The nails are detached with their roots, and may be easily pulled from the limbs. The scalp comes off readily. Temperature is an important condition in bringing about this high degree of decomposition. Taking the extremes of temperature, it may be said, that 16 to 20° R. in summer, will have the same effect in from 8 to 10 days as 0 to 8° R. in winter in from 20 to 30 days. We mentioned that at this stage of decomposition the corpse is covered with maggots. But where it was exposed to the open air or had lain in the water, it is not uncom- mon to find that it has been a prey to other animals, especially rats, but also dogs, cats, birds of prey, foxes and wolves. The evidences of such voracity are found on the chest and abdomen which frequently have been opened; and on the extremities, which, in many places appear as if dissected down to the bones. A little atten- tion will prevent us from confounding such lesions with traumatic effects. Finding a corpse in the condition just described, we may affirm with some degree of certainty, that the individual has been dead at least as long as above stated, but not that it could not have been dead longer, for this stage of decomposition differing thus from former stages, continues, generally, many weeks, even a few months, and but very gradually proceeds to the following stage: Corpses in a state of putrescence, of a green color, inflated and eacoriated, found one month after death, cannot well, cet, par., be distinguished from similar corpses found in from 3 to 5 months after death. 6. The stage of putrid colliquation begins in from 4 to 6 months after death; in corpses lying in warm and humid media, even sooner. The constant evolution of gas has opened the cavities of the chest and abdomen. Often the bones of the skull, too, have yielded in the sutures and the brain has escaped. All the soft parts are in a state of pap-like solution, or have been partly dissolved and consumed. Entire bones, especially those of the skull and extremities, are bare. Those of the extremities are often, even at this stage, detached at the joints; the fasciae and ligaments being destroyed. No trace of the physiognomy can be recognised. The ex- istence of mammae can no longer be determined, and since the external sexual organs have also disappeared, the sex of the individual can be known from the exterior habitus only in case the hair of the pudenda is still visible, which is often the case. As is well known, in a female, this hair is strictly confined to the mons veneris, in the male it extends to the umbilicus. According to Schulze, exceptions to this rule are not rare.” It is also still possible to determine the sex by searching for a ºtterus. - [To be Concluded.] * Jenaische Zeitschrift, Bd. iv. Heft 2, s. 312. SCIENTIFIC NOTES. S E A-S I C K N E S S . The Means of Relieving it. BY SIR. JAMES ALDERSON, M. D., D. C. L., F. R. S. Consulting Physician to St. Mary's Hospital, From the British Med. Journal, Mar. 9, 1872. The cause of sea-sickness and its possible amelioration is a subject particularly appropriate at the present time. It is more agreeable to offer suggestions for relief than to comment on the Sybaritic weakness which is generally displayed in impatience of the evils usually to be en- countered in a passage across the Channel. When we remember that not half a century ago, people, waiting days or perhaps weeks for fair wind and weather, were glad to consider a voyage of six hours of tossing and sickness as a very favorable one, one can hardly under- stand how the present generation feel it unendurable to submit to a single hour and a half after having started at a given time. Though, however, we must admit the fact that we are less brave in meeting discomforts than our predecessors, there is still satisfaction in diminishing those discomforts to the utmost in our power. We have seen the futility of various childish devices, such as stimulants, globules, ice-bags, etc., all of which, not being based on any true knowledge of the evils to be met, are merely empirical. Rejecting all of these, there- fore, it will be well to invite attention to a scientific ex- planation of the cause of sea-sickness, and to base on that explanation a proposal for a remedy. A suggestion was made sixty years ago by Dr. Wollas- ton, that sea-sickness proceeds from pressure of blood upon the brain; and this view is supported by patholog- ical observations, since injury or pressure on the brain is almost invariably attended by vomiting, which is its earliest symptom. Dr. Wollaston explains the way in which pressure is induced upon the brain during the motion of a ship at Sea, by reference to the action of mercury in the tube of a barometer. He says “that if a barometer be carried out to sea in a calm, the mercury will rest at the same height as when on shore; but when the ship falls by the subsidence of the waves, the mercury is seen apparently to rise in the tube which contains it.” I may add to this, that anyone who has carried a mountain-barometer, and has happened to let it descend suddenly, must have been sensible of a concus- sion of the mercury against the top of the tube, and must have both heard and felt the blow. In fact, the mere action of walking is sufficient, by the alternate rise and fall of the hand, to produce this effect. Dr. Wollas- 164 [APR. 6, 1872, TIH. H. C.T.I. NI c. ton considers that the action of the blood on the brain, at the moment of the descent of the ship, is identical with that of the mercury on the top of the barometer, and that there is an actual pressure, and even a blow, which, by frequent repetition, produces nausea and vomiting. Now it is to be regretted that Dr. Wollaston does not state the true scientific explanation of the apparent rise of the mercury in the barometrical tube, to which inaccuracy may possibly be referred the reason why so little notice has been taken of this valuable suggestion. It is not necessary here to analyse his statement with a view to refute it. The fact is undeniable, that contact does take place between the mercury and the upper part of the tube with more or less violence, and the proper explanation of the apparent rise of the mercury when the tube de- scends is this: that when the rigid tube falls, the mercury, having its own inertia, and not being attached to, or a part of, the tube, remains stationary—at least for a time; thus the tube is pushed down upon or over the mercury, and the concussion takes place. Exactly the same occurs between the brain and vessels on the one part and the blood on the other. The approximately rigid brain and vessels are carried downwards, the blood remains by its own inertia, and the consequence is to crowd blood into the vessels of the brain, and so press with increased force, producing a certain shock; this shock and the attendant pressure produce sickness and vomiting. The vomiting induced is of a peculiar char- acter—very different from that proceeding from a common disordered stomach; it occurs in a spasmodic manner, and violent retching remains after the contents of the stomach have been ejected. This continuous retching seems to indicate the repeated action of the in- creased pressure. * Referring to the experience of sufferers from sea-sick- ness, it is admitted by all that they are most sensible of the miserable feeling at the moment of the descent of the ship. They are also conscious at that particular time of an instinctive effort to sigh or take a deep in- spiration, the meaning of which is manifest. During deep inspiration, the chest is dilated for the reception of air, and its vessels become more open to admit blood, so that a return of blood from the head is then more free than at any other period of complete respiration; whilst on the contrary, by the act of expelling air from the lungs, the ingress of blood is obstructed. This obstruc- tion is proved by observation when the surface of the brain is exposed by the operation of trephing; a succes- sive turgescence and subsidence of the brain is then seen in alternate motion with different states of the chest. A deep inspiration, therefore, at the time of the descent of the ship tends to counteract the turgescence of the brain. Sickness is sometimes produced by waltzing. In this case the same theory of pressure on the brain holds good; but during rapid gyration in waltzing the blood is acted on differently: it is centrifugal force which causes the blood to rise in the vessels supplied to the brain. There is an additional cause of cerebral disturbance from the confusion of objects rapidly presented to the eye; from this comes giddiness. In reference to sickness brought on by swinging, I cannot do better than quote Dr. Wollaston: “Sickness, by swinging, is evidently from the same cause as sea- sickness, and that direction of the motion, which occa- ions the most piercing sensation of uneasiness, is con- formable to the same explanation already given. It is in descending forwards that this sensation is perceived, for then the blood has the greatest tendency to move from the feet towards the head, since the line joining them is in the direction of the motion; but when, in the descent backwards, the motion is transverse to the line of the body, it occasions but little inconvenience, because the tendency to propel the blood towards the head is then inconsiderable.” - This last observation of Dr. Wollaston, quite accurate as to the result, plainly suggests the practical bearing of the subject. Knowing the mode in which the ship's movement acts on the brain, we are at once furnished with the only rational way of averting sea-sickness. The first point is wholly to avoid the upright posture. Every one knows that it is a common practice to lie down, and this is done almost instinctively, but it is also known that to do so, though frequently successful, it is not invariably so. The way in which the motion in a swing effects the brain affords the proper explanation why lying down is not invariably successful; and shows that it is necessary, not only to take a recumbent posi- tion, but to lie in the right direction. A person lying down with the feet towards the bows of a ship is, whilst it descends in pitching, in the same position as a person in a swing descending forwards, in which case we have seen that sickness is produced by blood being forced upon the brain. On the contrary, a person lying down with his head towards the bows is, during the descent of the ship, in the position of one descending backwards in a swing, in which case the pressure by the blood will be towards the feet, and, therefore, relief rather than an inconvenience will be experienced, the tendency be- ing to reduce the natural supply of blood to the brain. It is necessary, therefore, not only to lie down, but to do so with the head to the bows; and it is highly desirable that this position should be assumed before the ship be- gins to move. There is a secondary advantage to be gained by closing the eyes, and so shutting out the con- fusion arising from the movement of surrounding objects. If the philosophical explanation here given be the correct one, which there is no reason to doubt, it adds one more to many unanswerable objections to the device of taking passengers in railway carriages on board gigan- tic vessels. No relief would be afforded by that plan to the miseries of sea-sickness, since, except in a perfect calm, nothing can prevent the rising and falling of the ship, and the consequent action of the blood upon the brain APR. 6, 1872.] TIEEI IEH C T II INT I. C. 165 The sitting posture would be equally unfavorable with the upright, and there would be, in addition, the com- mon motion of a carriage, which alone, with some per- sons, produces sickness. It is well to forbear imagining the miseries of sitting, shut up, face to face, with fellow sufferers, and, at the end of the voyage, of missing the one consolation of leaving the scene of your sickness, with all its disgust- || ing evidences behind, and getting into a clean and pure conveyance free from late contaminations, It is beside the subject of this paper to discuss the danger of unstable equilibrium from deck-loading, which must raise the centre of gravity and depress the meta- centre; also to hint that engineers may promise immu- nity from danger, whilst the melancholy fate of the Captain forbids us to trust in their scientific calculations. One thing is more than probable, that, in rough weather, deck-loading will produce heavy rolling motion. Short of the wild idea which goes by the name of the “Ferry scheme,” with all its doubtful experiments and certain tremendous outlay, much might be done to alleviate the discomforts of the passage across the Chan- nel. There might be larger vessels, with increased steam-power; better means for embarkation; shorter passages might be ensured, and comfortable arrange- ments might be made, so that every passenger could recline with the head to the bows of the vessel, whether on the deck or in the cabin. All these points might be ensured without any dangerous experiment, and there can be little doubt that the testimony of passengers would soon prove the efficacy of the plan. —sº-o-º--— sympathetic ophthalmia. From the Klin. Monatsbl. f. Augenh., Oct., Nov., Dec., '71. At the lastophthalmological meeting in 1871 (Heidel- burg). Dr. Cohn reported two cases of sympathetic ophthalmia the result of gunshot injury that are of in- terest from the peculiar form of the exciting cause. The first patient was struck by a chassepot ball at the outer angle of the left eye which fractured the orbital border. The eye was entirely blind. The ophthalmo- scope revealed a white spot bordered with pigment, eight or ten times the size of the papilla, it being impos- sible to tell whether it belonged to the retina or choroid, The Dr. decided, however, that it was an exudative | mass. The papilla could not be seen nor were vessels visible over the patch. It was in the outer portion of the fundus, corresponding with the part of the eyeball that was injured. - At the first examination the vision of the other eye (to right) was 50–70ths. There was no trace of iritis, cyclitis (inflammation of the ciliary body) or irido- cyclitis in the injured eye, simply total blindness; a magnesium light even not being recognised. Conse- of the latter with atrophy of choroid.” quently none of the usual conditions that produce sym- pathetic trouble. - All forms of treatment failed to produce any effect. An examination after five months showed the vision to be 40–70ths in the right eye. The patient could now only continue to use his eye for four or five minutes at a time. Enucleation of the left globe was practiced. An ex- amination of the extirpated eyeball by Prof. Waldeyer showed “chronic chorio-retinitis with plastic exudation on the inner surface of the retina and fibrous hardening Four weeks af- ter the enucleation the vision of the right was 50–50ths, a complete restitution. The second patient was injured on the upper lid of the right eye by a bomb, that scarcely left any trace on the skin. The sight soon became defective, and an ophthal- moscopic examination revealed a little brownish-red spot on the macula lutea of the size of a pin head sur- rounded by a yellowish-red zone from which extended a few small horizontal white lines. There was a central scotoma corresponding exactly with the macula lutea. By eccentric vision letters No. 20 of Senellen could still be made out. After some weeks the left eye, which at first was per- fect, could only read No. 3 Senellen. Enucleation was practiced on the 22nd April, and when the patient was seen last, 22nd August, the vision was perfect. Prof. Walkyer made the examination of the eyeball and found nd trouble in the iris, ciliary bodies, or media. In the macula lutea there was a small elevation that corresponded with the ophthalmoscopic picture. The author concludes that sympathetic trouble may arise without there being any affection of the iris or ciliary body. - Donders, eight years ago in one of the meetings stated that a peculiar form of sympathetic trouble may appear without any subjective appearances, which must be dis- tinguished from irido-cyclitis and irido-choroiditis. ' Also von Gräfe at the same time stated that such cases must not be confounded, as those not dependent upon affec- tions of the uveal tract usually afforded a favorable prognosis. —sº-º-º- MHEDICAL NEWS The **M) ſillain” and the **MIonel” A Letter from Dr. Epstein to the Cincinnati Israelite, Mar. 29, '72. CINCINNATI, O., March 20, 1872. ED. ISRAELITE.-A severe and almost fatal case of bleeding after the rite of “Milah” having recently occur- red in my medical practice, I am induced, by a regard for the welfare of the Israel of our country, to ask your favor of publishing in your widely circulated paper a few hints on the prevention and management of exces- sive bleeding after “Milah.” 166 [APR. 6, 1872. T ET H. c T.I.N.T.c. 1. “Hitooch” alone, performed with ordinary care, could hardly ever give rise to excessive bleeding, owing to the great contractility of the external skin. A little cold water—or still better, mixed with an equal part of vinegar—would be all that were necessary to stop the bleeding in ordinary cases. This part of the rite is a trifling affair, and devoid of any danger, 2. The skill and coolness of the “Mohel” shows itself in the delicate and apparently violent second act of “Priah,” which, as we all know, is essential to the com- pleteness of the rite as prescribed. It is well that the “Mohel” be not over-hurried at the performance of it. One cannot but admire the good tact of the usual ritual arrangement, making the father say his “B'racha” at the stage before the “Priah.” It would be even well to enjoin the father to pronounce his Hebrew clear and distinct (rather troublesome in certain regions of the world), and thus afford the “Moheſ” sufficient leisure to survey the wound, and prepare for a successful “Priah” I am not intending to presume to instruct the “Mohlim” in Israel any where; but as they are mostly not physi- cians (a fact greatly to be regretted), I merely wish to supplement their ritual knowledge by a consideration of the anatomical nature and arrangement of the tissue to be operated upon at this stage. This is the inner mem- brane of the “Orlah”—“Or Hapnimi.” It is far less contractile than the external skin, to “Or Hahitson,” and on that account remains, after the “Hitooch,” closely covering most of the “Atarah,” by which, I mean the entire head, and not only its lower projecting rim. This membrane is thin, translucent, and usually deli- cate, so that the color of the “Ataroh” is seen through it. Tracing the course of this membrane at this stage of the rite, we would follow it down to the groove, behind the projecting lower rim of the “Ataroh,” and there we would find the important fact, that it is more firmly at- tached to the “Guid,” thence it is reflected upon, and loosely attached to, the inner surface of the now partly amputated external skin—“Or Hahitson.” Tracing now again this delicate inner membrane—“Or Hopnimi”— around the “Guid” and in the groove, behind the pro- jecting rim of the “Ataroh,” we will find that it term- inates on either side, in one fold, on the lower surface of the “Ataroh,” at a little distance from the aperture of it. Here the delicate membrane, and the tissues underneath it, form what is anatomically called “the Frenulum,” or “Bridle,” which is very sensitive and vascular, i. e., more abundantly provided with nerves and blood-vessels than that membrane is elsewhere. The same vascularity exists, only in a less degree, at its attachment in the groove, behind the “Ataroh.” The skill of the “Mohel,” in performing “Priah,” consists in tearing this delicate membrane just sufficiently, and no more, so as to enable him to push it back with ease from the “Ataroh,” So as to expose it and its projecting rim completely all around. When well performed, the “Priah” is in itself a means of stopping the bleeding, for a torn wound bleeds less “Mohel” hastens away to his daily task of life. than an incised one; and the crowding of the folds of this membrane into the retracted remaining portion of the “Orlah” prevents the bleeding, and both speedily form a healthy soft cicatrix. In ordinary cases, there- fore, the usual cold water dressing of the wound is all that is necessary. But it may happen that this mem- brane is unusually tough, and when the “Mohel” is a little excited, he may overdo the performance of “Priah” and detach the membrane on either side from its attach- ment in the groove, behind the “Ataroh,” nay, may even tear it completely off all around the “Guid,” and reach violently into the “Frenulum” (above named), and lacerate it so that the membrane hangs in one or more shreds about or underneath the “Ataroh.” Here the good “Mohel” gets even more excited, and in the usual, but very unnecessary over-haste in per- forming the third part of the rite, viz., “M’tsitsah,” while he spurts about with blood, wine and water, like a small fire-engine, the good “Mohel” may entirely over- look the damage done and the danger induced. He vainly believes, that having pushed back the membrane in the groove, behind the “Ataroh,” or not, and having temporarily, by the “M’tsitsah,” staunched the bleeding, and adjusted his first cold water dressing, that all is done. The diaper is pinned on, the baby quieted, the rest of the ceremony gone through with, the “Mazel Tov” resounds all around, the congratulatory glasses clink to the good cheer of all present, and soon the good But, perhaps, before he reaches his business place, the careful nurse, or anxious mother, notices that the baby is unusually quiet, and examining it, finds the diaper bloody. In haste the Good “Mohel” is recalled ; and his perplexity and the parents' perturbation begin. What is to be done? [Here follow directions (Gentile) for checking hemor- rhage, the treatment of complications, etc. The whole article concludes with an editorial suggestion that “No Mohel should be employed unless well known to be an expert in the operation or a practical physician.”] THE SIGNIFICANCE OF DIAGNOSIS.—A man who was told by a physician that his wife had a cancer, borrowed a book in order to read upon the subject himself; after which he remarked to the physician that he did not think his wife had cancer: “her symptoms were more those of diagnosis, and if she had that it would kill her ſ” A VACCINATION MARTYR.—“Example is better than precept.” Acting upon this wholesome maxim, a Medical Practitioner stated during the progress of a case in the Court of Queen's Bench the other day, that he had been vaccinated 477 times. It was his practice to vaccinate himself when parents objected, to prove there was no harm in it. THE LIBERAL PARTY IN PRUSSIA.—It has been widely rumored and publicly stated that the eminent leader of the Liberal party in Prussia, and equally emi- nent pathologist and physician, Professor Virchow, was APR. 6, 1872.] TEEE CI.I.INI c. 167 about to quit Berlin, under circumstances of political discouragement, and to take up his residence in London. We understand that this statement is without founda- tion: in truth, Virchow's activity in parliament this winter has bºen crowned with very considerable success, the ministry having adopted some of the important principles for which his party contends. His position and influence as an uncompromising Liberal in Parlia- ment is probably as great now as ever it was, in spite of all the prestige that the ministry have acquried from the late war.—Brit. Med. Journ., Mar. 9, '72. - TREPANNING THE STERNUM.—This operation was performed upon a certain divine at Amsterdam who was by this means, freed from a great quantity of matter; and the heart was thus left so naked that, by applying a looking-glass opposite the wound, he could see his own heart beating, which he seemed to take some pleasure in. This was the noted Becker, who has written against the existence of devils.-Boerhaave's Institutes, English edition, 1746.—Brit. Med. Journ., Mar. 9, '72 A KNIGHTHooD FOR CORMACK.—The honor of Knighthood was formally conferred by the Queen on Dr. (now Sir) John Rose Cormack at the levée on Thurs- day. - A CROSS FOR VIRCHOW.-Professor Virchow has re- ceived the cross of Commander of the Italian order of the Crown from King Victor Emmanuel. —sº-o-º- CLINICAL, MIEM [O] RANIDA. Constriction of the Penis by a Wedding Ring. - BY DR. M. DUMAREST (Lyons). Interne des Hopitaux, From the Lyon Médicale, March 3, '72. G—, married, aged 59. Entry Sept. 27, '71. Eight days before entry, with a design at least original, he in- troduced his penis into his wedding ring. The ring was imbedded behind the glans and prepuce. The prepuce was in the condition of paraphymosis and the constric- tion of the ring had produced an ulceration of unequal depth: it was very deep on the upper surface of the penis, superficial over the urethra on the under surface. Micturition was difficult but still possible. The ring was divided in three segments, subsequent cicatrisation was rapid; two days afterwards he left the hospital almost cured. In this patient notwithstanding the violence and long duration of the constriction, though there was ulceration, there was no gangrene. Gangrene of the penis from mechanical cause is very rare, whether the cause be | artificial constriction or by paraphymosis. In truth ulcerations from a ligature of the penis, ulceration not only of the dorsum but of the much more resistant under surface, ulceration so extensive as to produce urethral fistula may exist and yet gangrene will not ensue. M. Laroyenne, notably, has seen two cases of ulceration of this kind in children fearful of punishment who tied the penis to avoid wetting the bed. Our patient is a proof that sphacelus does not present as easily as most of the authors claim. It is useless to add that fatal mortification of the penis may ensue if the constriction be of long duration and excessively violent. As to paraphymosis it is gen- erally admitted that it may be easily complicated with gangrene; far from being true, this complication is ex- tremely rare. M. Laroyenne has never observed it. In all cases it easily produces ulcerations of the prepuce and furrow. This ulceration may cause the most serious dangers on the under surface, if it involve the urethral canal. It may be the point of departure of an urethral fistula or indeed of an immediate urinary infiltration or finally of a future stricture. But the circulation is ex- tremely rarely sufficiently arrested at the outset to in- duce, by the sole fact of constriction, mortification of the glans or the cavernous body. M. Demarquay” and many others with him are wrong, then, in admitting its frequency, with either phymosis or paraphymosis. Cases of ligation or constriction of the penis by foreign bodies are not rare. A few are encountered everywhere. We cite a few as follows: e M. Demarquay has reported two; the first was pub- lished by M. Leteinturier, of Havre. The introduction of the penis into a ring was followed by mortification of the skin of the entire penis and the anterior part of the scrotum. The patient was a peasant who had used this token of love from his mistress in this way as a charm. The second was that of Bourgeoist who did not hesi- tate to remove a portion of the corona glandis to facili- tate the detachment of the constricting ring. It was a radical proceedure: the patient was released from it with a few eschars upon the prepuce and the dorsum. penis from which he recovered in two months. Nat. Guillot reported the case of a baker who in the first months of marriage permitted his wife to pass over the penis the bond which she had carried on her finger. This ring was gold and a pharmaceutist conceived the ingenious idea which released the patient. He dissolved it in a bath of mercury. - . M. Guibout, in 1868, communicated to the Société des Hôpitaux the case of a man of more than 60 years of age who had introduced his penis up to the root in seven rings of copper, very small and very strong, “to procure,” as he said, “a few moments of pleasure.” These rings remained in place eleven hours. The penis had become hard; cyanosed, extremely turgid and of ganrenous hue. After a thousand efforts the seven rings e- *Archives de Méd., 1870. f Mém. de l'Acad. Roy, de Chirurg., vol. I. 168 [APR. 6, 1872. TIEEE CI, IISTI c. were successively divided. In eight days every local trace had disappeared. Two well known cases we finally cite; the one of a soldier in whom Larrey found the penis fastened in the socket of his bayonet, and the other that of the bather found suspended by the penis from the cock of his bath tub. STRANGULATED HERNIA REDUCED BY DIGITAL DILATATION.—Dr. Acaldo da Savigliano reports that he was called to a patient aged 63 years, with an in- guinal hernia of forty years standing. - In consequence of a gastronomic excess this patient was attacked with intense colic and incessant fecal emesis. Futile essays at reduction by taxis had been made by two physicians. Ice had been applied, blood had been let, the patient had been put into a hot bath. On the following day, the patient being in the same condition, a renewed attempt at taxis was made and then, 18 hours after strangulation, an operation, was performed. This operation consisted in an incision parallel to the long axis of the tumor, division of the sac and exposure of the intestine which was found livid but still warm. The operator then introduced his finger beneath the ring as a guide to the bistoury, but perceiving that after having insinuated the little finger he was able to introduce the middle finger, he dispensed with the incision and succeeded in returning the intes- tine into the cavity of the abdomen.—Gazetta Med. di Torino–Bull. de Therap., Feb. 15, '72. CHLOROHYDRATE OF NARCEINE by Hypodermic Injection.—M. Paul Pétrini reports, in his dissertation on this subject fourteen cases in the additional experience of Prof. Béhier (Hôtel-Dieu) and in the different depart- ments of this hospital with the following conclusions: 1. In a dose very minute, the chlorohydrate of narceine possesses an action decidedly sedative. 2. It is much superior in sedative action to the salts of atropia. - 3. Its anti-emetic action is equal if not superior to the chlorohydrate of morphia. 4. As a hypnotic, even after morphia and the other preparations of opium have failed, the chlorohydrate of narceine in dose most minute produces Soporific effects. 5. The chlorohydrate of narceine acts with the same efficacy and with the same rapidity in whatever part of the body injected. - 6. Even in minimum dose the chlorohydrate of narceine produces a transitory elevation of temperature and a momentary augmentation of pulse and respira- tion. There is observed at the same time a reduction of arterial tension.—Bull. de Therap., Feb. 15, '72. TREATMENT OF ENURESIS.—Cases of enuresis are, as a rule, very troublesome to deal with ; and, therefore | though I have nothing new to recommend, I think it may be worth while to record a very successful case. Emily B., 6% years, healthy, and of healthy parents, had from infancy up to November last, been used to wet the bed nightly. All sorts of treatment had been tried in vain. I ordered the lower part of the spine to be sponged nightly before she was put to bed. This has been continued every since, and she has only once wet the bed. This speaks for itself. I shall continue the treatment for some months longer, and have no doubt a permanent cure will have been effected.—Savage—Brit. Med. Journ., Mar. 9, '72. GRANULATIONs of THE Conjunctiva TREATED BY ELECTRICITY.--Dr. Arcoleo of Palermo has already employed this remedy with success in these cases (Eléments d'electrothérapie oculaire in Gazetta Clinica di Palermo 1870). Shortly after Dr. Kohn of Berlin obtained satisfactory results in seventeen cases; this physician employed a battery of only one element. Having protected the eye with Jaeger's plates he placed the heated platinum wire on the eyelid. Dr. Kohn, thus had recourse to thermal galvano-cautery, while Drs. Arcoleo and Rodolfi secured the chemical galvano- cautery. Dr. Schivardi's method is thus described: The negative pole of the battery composed of two ele- ments of Bunsen is applied by means of a buttoned sound to the inverted surface of the upper lid. The positive pole is applied to the nucha by a sponge sat- urated in salt water. The first session is of ten minutes duration. Dr. Schivardi publishes three observations of old granulations lasting respectively, in duration, two, three and eight years. The first case was cured in five sessions; the second was decidedly improved in two sessions; the third, aftected also with concomitant blepharitis and pannus, not only recovered from these affections, but also regained sight in nine sessions. To practice electrisation three assistants are required, one to hold the positive pole, the other the negative, the third holds the lid reversed and the head fixed. This application of electricity is now to be taken into serious consideration in the medical world, for the dis- cussion of the therapeutic value of electricity in ocular maladies is made the order of the day for the next con- gress of the Italian ophthalmological association.— Il Morgagni—Bull. Therap., Jan. 30, 72. XYLOI, IN SMALL-POX.—I have during the last few of the prevailing epidemic of small-pox here, used xylol with most satisfactory results. I do not, however, agree with giving it in capsules, as recommended, simply on account of the great difficulty generally experienced by patients in Swallowing during the severe stages of the disease; nor is it miscible with water alone, as stated. I have given it in doses to adults of 20 minims every three or four hours, either in milk or mixture of almonds; the latter I prefer. I should be glad to hear of its ex- tensive use, as I believe in its efficacy, although I can- not define its specific action.—H. B. Hurman, Bridge- Water.—Brit. Med. Journ., Mar. 9, '72. ºmmºn- The Divided Medicine Com’y, CINCINNAT1, OHIO. The Company have the honor of bringing to the notice of the Profession, this NEw AND ExCEEDINGLY PRACTICAI, METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. The Divided Medicines are prepared by FREDERICK KRAUs, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MORE. - - .e. The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every square will consequently contain accurately measured quantities. But not only SOLUBLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINEs. - €º - * This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain; # *, *, *, *, and even idoo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. •', - - Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE To SPOIL BY ANY LENGTH of TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calls with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. For Samples, Price Lists, and Agencies, address Hoºese, Or FRFDERICK KRAUS, Chemist and Druggist, Walnut Hills, Cincinnati, O. - MR. FREDERICK KRAUs: . CINCINNAT1, February 15, 1871. . Dear Sir—The specimens of your “Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: ſº- SULPH:MORPHII......................3% grain in each square. ARSEN:ACID......................... .1-20 * tº *ś::::::::::::::::::::Aerºn inºch Tºrº. §º: lºsiºn mºnº é & COPPER * * * * * * * * * * * * * * * * * * * a see wº}% & ſº . :, RESPECTFULLY YoUBs, E. S. WAYNE, Analytic Chemist. Carriage Manufacturer, re 9 and 11 East Sixth Street, bet. Main & wana, I MARE NOTHING BUT Frasz, czass work, Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, . such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of --- LIGHT FAMILY CARRIAGEs Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive variety of light elegant designs of different cost and finish. In vehicles especially adapted to PHYSKEFANS” {|SE. The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. The superiority of my light gentlemen’s buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price lists furnished on application. References to Dr. W. W. Dawson and all the leadin v/ . . . e & . g < Tº ºr 2. º º “... 2 º' A ššº §º 2% % - 2 22. % Ø ºf . 2.". 2 ºf %2% - % % 2- Sº 24.3 Šºć Fºº Sºs E-E: :// Zºº :===s sº % *-*- %92ſº GooD s AMARITAN HOSPITAL. The GOOD SAMARITAN HOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner of sixth and Lock streets. It is handsomely furnished throughout * * provided with all the necessary ap- pointments of a First-class Hospital, Porticoes, with commanding views, surround the whole house, and wide halls and abundant windows secure that full and free ventilation which is so essential to health and comfort. Service is furnished by the - SISTERS OF CHARITY, Under the Superintendence of the well-known SISTER ANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. Theºregular Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each Professor presiding over his own especial department. Patients may, however, select from the regular profession of the city any physician of their choice. The GOOD SAMARITAN HOSPITAL presents extra inducements to Invalids throughout the State as a safe and quiet asylum in any case of protracted illness, or in cases, more particularly, requiring Surgical Operation, where some stay is necessary in after treatment. Rooms vary in price, according to the character of appointments necessary and service required, ranging, in general terms, between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand of service. - Gº" Address, SISTEE ANTHONY, - Hospital of the Good Samaritan, Corner of Siacth and Lock Sts., Cincinnati. Ohio- CINCINN ATI. E" A G U L T Y. J A M E S G R A H A M, M. D., D E AN, Professor of the The Ory and Practice of Medicine and Clinical Medicine. ROBERTS BARTHOLOW, M.D., W. W. DAWSON, M.D., Professor of Materia Medica and Therapeutics. Professor of Principles and Practice of Surgery and Clinical Surgery W. H. GOBRECHT, M.D., C. D. PALMER, M.D., Professor of Anatomy. Professor of Medical and Surgical Diseases of Women. P. S. CONNER, M.D., - T. A. REAMY, M.D., Professor of Surgical Anatomy. Professor of Obstetrics and Diseases of Children. JAMES T. WHITTAKER, M.D., JOHN L. CLEVELAND, M.D., Professor of Physiology. Demonstrator of Anatomy. SAMUEL NICKLY'S, M.D., - CHARLES KEARNS, M. D., Professor of Physics and Medical Chemistry Assistant to the Chair of Surgery. © VVT. VV . SFXEI.Y. , N.I. D., IP 1"ofesso of ID is e º uses of the Iºye arid IHEar, andl Secretary of the Faculty. --- $ T. LOU18 BRow N. M. I.). I'rosecutor of Anatomy. F. NoHLE, Janitor, College Building, Sixth St., bet. Vine and Race. - - y } ge 12. g y -* Printed and Published by Non R1s & MURRY, Medical College of Ohio Building, Cincinnati, THE CLINIC, 19t.JBLISHED EVERY SATUR DAY. *... ... ?" * * "Ya Vol. 2. HITTAKER, M. D. No. 101 West Ninth Street, Cincinnati. JAS. T. VV _A_SSOCIALTIE, ETXITOR,S. W. W. D.Awson, M. D. THAD. A. REAMY, M. D. P. S. ConneR, M. D. C. D. PALMER, M. D. W. W. SEELY, M. D. ``SAMUEL NICKLEs, M. D. CHAs. KEARNs, M. D. JNo. L. CLEvKLAND, M. D. RoBERTs BARTHollow, M. D. W. W. SEELY, M. D., - farasvara. No. 118 West Seventh Street, Cincinnati. CLUB RATEs, - 4 Copies to one address $ 7.00 6 & & & & 10,00 12 & & & 4 18.00 C O N T E N T S. *-*-*. • Page. ORIGINALL ARTICLES A Review of Some of Prof. C. E. Brown-Séquard’s JRoberts Bartholow, M. D... TRANSI LATION The Process of Decomposition (An Abstract from Caspar’s Gerichtl. Medicin. Berlin, 1871) scIENTIFIC NoTEs Extracts from Quetelet’s Science of Man—Sea-Sickness—Prof. Laycock on Ears—Wentral Body Heat 174-177 M IELDICAL NEWS. American Medical Association—Kentucky State Medical Society— Signs of the Times—Medical Science in Quito—Salaries of Phys- icians B. C.—A Munificent Donation—A Heavily Backed Journal–French Patriotism—The Oldest Medical College in the West—Graduates in Medicine in 1872............................ CLINICAL MEMORANDA Opinions, by T80 º .180 Ergot in Varices—Management of Epilepsy HOME NEWS. THE curious processes of saponification and mummifi- cation meet with full discussion in the exhaustive chapter on the process of decomposition concluded to-day. Quetelet's recent developments from his continued statistical researches are an extension of those investi- gations which have long ago made this method of de- duction famous. Buckle, it will be seen, is only his ex- ponent in political economy. No one can fail to be interested with the chapter on the conformation of the ear as an indication of cerebral development. The discovery of the effects of ergot on varicose veins as detailed under Clinical Memoranda, is another of those happy results now becoming so frequent, from the scientific study of the action of medicines, C IN C IN N A TI, A PRIL 13, 1872. Editor. . 92 wres J. TAFT, TERM s—$2.00 a Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editor: • * : * All Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer. .* No. 15. coArs e co- Fashionable Hatters, IMPORTERS AND MANUFAUTURERS OF EABEES” FºrS, T ENOTTERTEL ST. Opposite Post Office, CINCININATI. ºrSpecial Inducements to Medical Men. 120CART.ºrillman Bº **** fill §N. ºbesidiºs ANº. º Editor Dental Register J. & W. TAFT, TXETNTTIST's 117 WEST FOURTH STREET, CINCINNATI, O. A Monthly Journal, CONTAINING 48 PAGES, Devoted to the Interests of the Dental Profession, --- & ºr * * * sº sº * *** *- º,” > * * & As —-mºsºmſ” sº- * tº *** &4. r —-ar * - f * , *-* * _f ; ºr - sº. **as 2-ºx * * **** --- *r-sº-gs ** º -** *- *** *. * *~. *. R & . . . 57. * ". . 111 S O * * . 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CALOMEL * % § { •6 $6 * * COPPER • . . . . . . . . . . . ***** tº e º is ſº gº tº % 6 & - Respectfully YoUBs, E. S. WAYNE, Analytic Chemist. *-*. vol. 2..] s A T U R D A Y, A P R I L 13, 1872. [No. 15. O R. I G IN A I, A R T I C L E S. A Review or some or prior. C. E. anows. . seouard's opinions. By RoBERTS BARTHOLOW, M. D. The lectures of Dr. Brown-Séquard published in the three preceding numbers of THE CLINIC, furnish us much material for reflection. If his views are not always tenable, at least, they are interesting and suggestive, and exhibit that fertility in invention and independence in statement characteristic of the pioneer. Few of our readers need be told how numerous and important have been Dr. Brown-Séquard's contributions to knowledge. Many of his discoveries have taken.permanent place in science. But the very qualities of mind which are most necessary to the successful prosecution of discov- eries often unfit the investigator for a patient and candid examination of the views of others. Hence, his opinions and the observations on which the opinions are based, are apt to be one-sided. It requires the work of many investigators to develop the whole truth. In illustration of this narrowness of perception which comes of devotion to a special line of investigation, I may take Dr. Brown-Séquard's views on the importance of reflex action from peripheral irritation in the causa- tion of various convulsive and other morbid phenomena. It is undoubtedly true that he has admirably shown by vivisections how injuries of the spinal cord and of cer- tain nerve trunks, may result in such an exaltation of the reflex faculty that irritation of the epileptogenic zones, will be followed by epileptic seizures. This happy demonstration has led him to a generalization of the influence of reflex action so sweeping, as to prac- tically exclude from consideration the large body of facts demanding a very different interpretation. His central idea is that peripheral irritation causes an in- crease of .the activity of some, and a suspension of the activity of other parts of the nervous system, and the symptoms of disordered function which ensue are thus produced. Irritation of the epileptogenic zone causes a suspension of activity of the cerebral hemis- pheres (loss of consciousness), and an increase of activity of the “spasm centre” (convulsive seizures). He thus for the time being ignores the influence of local brain lesions in causing definite symptoms, and indeed he affirms “that we may not refer symptoms to specific lesions.” He also failed to advert to the now well-estab- lished fact, that peripheral injuries cause changes in the T H E CI, IISTI c. 169 nervous centres with which the points of irritation are connected. In the space and time at my disposal, I cannot do more than examine into these two questions and make some observations on the points of practice "evolved by Brown-Séquard from his theories. 1. Are there special centres of function in the brain, and do injuries of them cause definite symptoms ? Dr. Brown- Séquard assumes the negative and brings forward the various and contradictory symptoms, and sometimes the absence of symptoms in brain diseases in support of his side of the question. I think it can hardly be denied that the present tendency of medical belief is to con- sider the brain a compound organ made up of many parts having different functions. This is partly ad- |mitted by Dr. Brown-Séquard when he states that the left hemisphere is more immediately concerned in the function of language. “Indeed” he says “cases of aphasia following right sided lesions—unless the indi- vidual be left handed—are exceedingly rare.” It is true Broca's localization of articulate language in the third left frontal convolution, although supported by many observations, has been opposed by many and cannot now be considered as established, but further investigations will hereafter, no doubt, as former obser- vations have, more conclusively, limit the seat of this faculty in the left hemisphere. That extensive de- struction of brain tissue should occur in the right hem- isphere without any pronounced symptoms need not occasion surprise, when we reflect that the left hemis- phere is the first developed, and as the facts show, first and chiefly educated in the performance of functions. That lesions in various parts of the brain should occur without producing characteristic objective evidences, and that the symptoms of a certain form of brain dis- ease may vary in different cases, is a condition of things not unparalleled indeed, in the diseasesofother organs the physiological functions and morbid changes of which are better understood. It is not uncommon for a latent pneumonia to exist without the usual signs, or for a hepatalgia to be confounded with hepatic colic. Will we therefore ignore physical diagnosis in diseases of the lungs, or rational signs, in determining the character of hepatic diseases? If it be shown in numberless instances that a hemorrhagic extravasation in the left corpus striatum, will cause right hemiplegia, what will be the value of some rare instances in which paralysis followed on the same side as the injury 2 Such excep- tional instances would rather indicate a deviation from the true structural type. Although alternating hemi- plegia may occur from disease of the corpora striała, yet who does not admit that it is a most significant symptom of disease of the pons Varolii. Paralysis of the extremi- ties on one side and of the third nerve on the opposite side most surely indicates disease of a crus cerebri. Paresis of muscles to which the 7th nerve is distributed is also alluded to by Dr. Brown-Séquard as due to widely different lesions and as therefore wanting in significance as a symptom, but is it not perfectly well known that 170 [APR. 13, t&72. TIEHE TER C T , T N T C . we may fix with great accuracy on the position of a lesion of this nerve, whether in its trunk or in the centre from which it takes its origin? Paralytic affections of the various cranial nerves, enable us to locate with the greatest certainty the position of adventitious products in the brain, notwithstanding exceptional instances may occur due to causes which we cannot now well explain. To deny the value of these signs and to exaggerate the importance of exceptional instances, is to discourage all attempts at accuracy in the diagnosis of brain lesions and to relegate the study of these affections to the ob- scurity of a century ago. This is all the more sur- prising in Dr. Brown-Séquard who has been celebrated for his diagnostic acumen. His discouraging observa- tions may, however, have their inspiration in the desire of the specialist to exaggerate to ordinary professional minds the difficulties, and the special skill and knowl- edge necessary for success, in his special field of prac- tice. Dr. Brown-Séquard does not always, however, dis- courage diagnostic refinements in nervous diseases. He has indeed, distinguished himself by subdividing the functions of the organs concerned in his favorite doctrine of reflex action. Thus he makes no less than “eleven kinds of nerve fibres” having “distinct functions” (Lectures on the Diagnosis and Treatment of Functional Nervous Affections Part 1. p. 11). He has carried this subdivision to the utmost limit of plausability, for, in a recent publication he affirms “that the conductors capa- ble of causing convulsions are distinct from those which serve for the voluntary movements” (Archive de Phy-| siologie Vol. 2, p. 776). Vulpian and Philipeux have shown, however, by transplantation of nerve fibres, that the nerves merely conduct nerve force, and indifferently whether it be of motion or sensation. If there be so many kinds of nerve fibres, there must be special nerve cells capable of reacting definitely to the impressions received. Hence, it follows, these nerve cells must con- stitute centres, the disturbance of which by disease, must cause definite reactions, or symptoms. Our ina- bility in any case to locate the seat of the alterations as manifest by the symptoms (anaesthesia, hyperasthesia, etc.) is due of course to the imperfection of our knowledge. Examples showing contrary to Brown-Séquard’s views, that symptoms indicate lesions, might be greatly multi- plied, but I pass for want of space from these general considerations to the special question of centres of func- tion in the brain. The one-sidedness of Brown-Séquard's opinions may be best shown by bringing forward some of the more modern views regarding functions of certain parts of the cerebra! mass. The facts of comparative anatomy show that intellectual power is determined by the development of the cerebral hemispheres. In the gray matter of the brain, it is now held, resides those complex functions included in the term, intellection, and hence upon the depth and complexity of the convo- lutions, depends the mental power of the individual. This well known fact has been illustrated by the re- searches of Lockhart Clarke and Meynert, on the differ- ent layers of the cortical substance. Modern investiga- tions more and more tend to establish the connection of the faculty of language with the left hemisphere of the brain, although it may not be limited to the third fron- tal convolution as maintained by Broca, or to the walls of the Sylvian fissure as held by Meynert. Dr. Brown- Séquard entirely ignores the observations of Meynert in regard to the changes in the cornu ammonis which occur in epilepsy and other motor diseases. Careful micro- scopic researches have demonstrated the constancy of organic alterations of the cortical periphery (MESCHEDE, Virchow's Archiv., 1865. LOCKHART CLARK, Lancet, &c.) in cases of general paralysis of the insane. The facts showing the connection of the tubercula quadrigemina. with the function of sight are too numerous and direct to be overcome in significance by the contradictory ex- amples brought forward by Brown-Séquard—many of which may have arisen in errors of observation. Although denying the existence of centres of function Brown-Séquard admits the importance of the medulla oblongata as the seat of convulsive movements in epi- lepsy, yet he is silent in regard to the “spasm centre” of Nothnagel and the “inhibiting centre” of Setschenow. (Virchow's Archiv für Pathologische Anat. and Phys. Band xliv. Hft. 1). Four systems of inhibitory nerves are now pretty gen- erally admitted by physiologists: the cardiac, the respi- ratory, the intestinal, and those which restrain the reflex actions. We are more particularly indebted to Weber and Budge for the demonstration of the first, to Rosen- thal for explaining the second and to Pflüger chiefly, for pointing out , the third, the inhibiting centre of Setschenow being the fourth. To these must be added the “cilio-spinal region” of Budge and Waller. The ex- istence of all these centres rests upon the same basis of proof as Brown-Séquard’s discoveries—upon experiments on animals and the results of disease in man, and are just as much entitled to credence. 2. Are the symptoms caused by peripheral irritation, solely due to reflea action ? Dr. Brown-Séquard answers this question in the affirmative, In assuming this posi- tion he ignores numerous facts which require a different interpretation. Especially from the point of view of the therapeutical application of counter irritation, does this question demand our most earnest attention. It is certainly true—and it is a demonstration the impor- tance of which it would be difficult to overestimate— that injuries of the spinal cord and of nerve trunks is followed by epilepsy on irritation of certain zones Sup- plied by the fifth and the spinal accessory. But we should not be so dazzled by the brilliancy of this dem- onstration as to lose sight of a fact which we obtain from Dr. Brown-Séquard, himself, that these epileptic attacks do not follow immediately on receipt of the injury, but appear after a period of three weeks. By this time the influence of the injury has been sufficiently exerted to induce changes in the “spasm centre.” Peripheral irri- APR. 13, 1872.] 171 tation—for example counter irritation—is too commonly supposed to produce effects merely through reflex action —the irritation of the surface being reflected from the centre to the vaso-motor nerves. For this very partial and incomplete view of the modus operandi of counter irritants Dr. Brown-Séquard is largely responsible. His famous experiment of irritation of the skin over the lumbar region causing contraction of the vessels of the kidney has exercised an undue influence in shaping opinion on this subject. Peripheral irritation does more than simply excite reflex action : it induces, if long con- tinued, structural changes in the centres of reflex action. A variety of facts go to prove this. In the blister treat- ment of acute rheumatism the reaction of the urine is changed from acid to neutral or alkaline. Sometime ago Waller, and afterwards Turck, demonstrated that section of the roots of a spinal nerve will be followed by atrophy and degeneration of the posterior root and of its connections upward in the spinal cord. Vulpian has shown that after section of the nerves of a limb no- table atrophy takes place in that part of the spinal cord from which these nerves take their origin. Duchenne de Boulogne and Joffroy, have apparently established the existence of two sets of cells in the cord—trophic and motor. Numerous clinical observations have ren- dered it highly probable that trophic centres exist in the cerebro-spinal axis. It follows from these facts that peripheral irritation not only excites actions of a reflex Kind, but induces changes in the cells of the trophic centres. This latter fact, Dr. Brown-Séquard admits in his last lecture when alluding to the observations of Turck. If changes take place in the centres from per- ipheric irritation, shall we not refer the morbid phenom- ena which result rather to these centric lesions? So in Dr. Brown-Séquard's epileptic guinea pigs shall we not refer the convulsive siezures to centric lesions—for is it not admitted that the convulsions occur not at once, but some weeks after the peripheric injuries? In fact Westphal has very recently shown that min- ute hemorrhagic extravasations occur in the medulla of these guinea pigs, and that the convulsions do not begin until this process has taken place. There is one other fact relating to counter irritation | in regard to which Brown-Séquard is unaccountably silent. I now refer to the difference in effects which fol- low slight and temporary irritation, and the deeper and more enduring injuries. Especially when he came to discuss the influence of his theories on his therapy, we should have had some light thrown on this important question. It is now well understood that whilst slight irritation of the terminal filaments of the sensory nerves -as the action of a mustard plaster—causes reflex con- traction of the organic muscular fibre of the arterioles, deep injuries by exhausting the irritability of the sym- pathetic, induce paralysis and hence dilatation of the vessels. This last mentioned result is illustrated by the ulceration of the duodenum which ensues after deep burns of external parts. Finally, Dr. Brown-Séquard the range of utility of which is so much wider. argues ill, indeed, for the therapeutical skill of a special- does not allude, except in the most indefinite way, to. the changes in the trophic centres wrought by severe or long continued peripheral irritation. 3. Dr. Brown-Séquard's therapeutical maxims. In read- ing his lectures on “The Treatment of Functional Ner- vous Diseases,” and his most recent utterance in the last number of THE CLINIC, it must appear evident to any practical mind, that an experimental physiologist, devoted to a theory of the truth of which he is thor- oughly persuaded, is a poor guide in therapeutics. His special views constantly intervene to bias his opinions and his practice. This fact is conspicuously shown in his last lecture. Recognising the all-sufficient influence of peripheric irritation in the production of morbid phenomena, his remedies are comprised in two classes; those that cause, and those that allay peripheric irrita- tion. “It is a matter of indifference by what means this arrest of activity is produced. It is only essential that we recognise that any function may be arrested by dis- tant irritation,”—in this language Dr. Brown-Séquard formulates his theory. The practical outcome of his therapeutical speculations is seen in his suggestion to stop an epileptic paroxysm—“to arrest activity”—by injecting carbonic acid into the larynx His favorite measures are the cautery to a white heat, and ice. “The most powerful means of changing the state of the circu- lation is the heated iron,” and “ice ranks next to the cautery.” He thus comprehends all morbid processes in the blood supply of the affected part—all therapy, in the means of acting on the vessels. • - Whilst Dr. Brown-Séquard makes much use of on of the physical forces—heat—it is a matter of extreme surprise that he utterly ignores another—electricity— It ist in nervous diseases, that he has not yet adopted the applications of the constant and induced currents, either in diagnosis or in treatment. It is impossible for him to ignore electricity. The literature of the subject is too vast, the names of its advocates too influential, the claims for its therapeutical efficiency too strongly urged, to permit him to pass it over in silence. Finally weshould not fail to note that Dr. Brown-Séquard offers us nothing new in the treatment of nervous diseases, except his very extraordinary and impracticable sugges- tion to arrest the epileptic paroxysm by injecting car- bonic acid into the larynx. The observations which he has made in his lectures in Cincinnati were before per- fectly familiar to the medical profession. But we should not expect much in the direction of practical therapy. Dr. Brown-Séquard's strengh lies, of course, in origi- mal investigations—in evolving theories from a basis of experimental inquiry—a much higher plane for intel- lectual effort, it is true, than drug-giving. To practical physicians belong the humbler task of applying to the treatment of disease the new views of normal and disor- dered function which are disclosed in his researches. The very bias which he has in favor of his own opinions and his apparent indifference to the researches and dis- coveries of others, by narrowing his breadth of view, reduce his therapeutical resources to the level of any ordinary medical practitioner. - 172 [APR. 13, 1872. TIEEE C T.I. NI c. T H E P R o o Ess o F D Eco M P os IT I o N. An Abstract from Caspar's Handbuch der Gerichtlichen Medicin. Berlin, 1871. Continued from No. 14. Saponification. The constant effect of water on a corpse in a state of colliquative decomposition, arrests that process, whether the corpse lies actually in water, or only in very damp earth. By the union of margaric acid and ammo- nia, in many corpses, a process of saponification sets in, and a peculiar fat, known as adipocire (Leichenfett, Fettwachs) is formed. This occurs more readily in fat bodies; hence the corpses of children saponify more easily than those of adults. Caspar says it is difficult to determine the time when this process first begins. Referring to Devergie's opinion that it takes the body of a person drowned, one year, and that of a person buried in the earth three years, to entirely saponify, he cites the case of a newly born child, buried in very damp earth, one-third of whose body he found saponified only 13 months after death; and the case of a foetus which he found entirely imbedded in adipocire 64 months after burial. He thinks the formation of adipocire will hardly assume any considerable dimensions until after 3 or 4 months in water, and 6 months in damp earth. The fat itself cannot be mistaken, even by the most unskill- ful. It is homogeneous in its formation, white, or with a slightly yellowish tint, soft under the knife and fusible in a flame. Its odor is not very disagreeable, and rather resembles that of musty cheese. The muscles, with their tendons and aponeuroses are first attacked, but there is no organ in the body that does not succumb to the process. According to Güntz's experiments, the adipocire of a corpse is of greater volume than all the fat the body posessed. This is important when we wish to determine the weight of the corpse of a newly born child for the purpose of calculating its age. Caspar, like Devergie, has never seen an entire corpse completely Saponified, but he observed the complete saponification of a foetus in utero. Mummification. This is the well known, remarkable and complete dry- ing up of the body, in which it retains, generally, its form, and even its features, (though the latter may be distorted), and assumes the brown color of rust. The skin of a mummified corpse is dry; it feels like parch- ment and lies close to the bones. Its odor is not at all like the odor of decomposed bodies but resembles that of old cheese. The interior organs have either entirely disappeared, or they have been changed into a dark brown, dry mass, the organic parts of which cannot be formed, may last thousands of years. distinguished by the naked eye. Artificial mummifica- tion, by the injection of arsenic, and the various methods of embalming was known already to the Egyptians. But the general conditions of natural mummification are but little known. It occurs as well in corpses that are exposed to a continuous desiccating draught of air, in vaults for instance, as in those to which the air has scarcely any access at all, e. g., corpses buried in leaden coffins. Caspar thinks it cannot be doubted that corpses | readily mummify in dry, hot places, and that the tales of mummified entire caravans, in the Arabian deserts, are not incredible. Certain it is, that a mnmmy, once We could not, therefore, determine the time of death in the case of a corpse found mummified, with any degree of probability. Successive Changes of the Corpse, Interiorly. Caspar says that the interior organs are never and under no conditions subject to a uniform effect of the process of decomposition. From his long experience and independent of the assertions of Bichat, Orfila, Devergie, Güntz and Hébread, he feels justified in giving the following data as reliable: - 1. The trachea, including the larynx, is attacked first. As long as the discoloration on the abdomen is confined to separate green spots, the mucous membrane of the entire trachea, down to the bronchi, is a pale color, ex- cept when death was caused by suffocation or laryngitis. But as decomposition progresses and the green spots on the abdomen become confluent (though the corpse, ex- teriorly, may otherwise appear fresh) the mucous mem- brane assumes a uniform dirty green, greenish-brown, cherry-red, or brown-red, no vascular injections being visible in this discoloration. This takes place, in sum- mer, in from 3 to 5, in winter, in from 6 to 8 days. Caspar warns us not to mistake a simple and early phenomena of decomposition for capillary injection and the result of death from suffocation or drowning. Age, constitution and mode of death make here no difference. In the further course of decomposition the mucous membrane becomes olive-green, the different parts of the cartilage separate, but months pass before they en- tirely disappear. 2. The substance of the brain of neo-nati and children up to one year of age follows next. - 3. No organ is found in so many different forms as the stomach. We find it of various sizes, inflated with gas or collapsed, partly or entirely filled with the re- mains of food, or empty. As it imbibes coloring matter freely, the mucous membrane will look yellowish from the contents of the gall bladder, bloody and black from medicines and dark juices of fruit, red from red wine and so on, to say nothing of the dangers brought about by sickness, catarrh, inflammation, corrosive poisons or the jelly-like softening of the process of decomposition. The stomach decomposes early. The first traces of de- composition appear in from 4 to 6 days in the fundus, in the shape of detached, dirty red spots, which are not APR. 18, 1872.] T H E c T, IISTI c. 173 circumscribed, very irregular in form, of various sizes, some as large as a dinner plate. The reddish patches are, generally, traversed by blood-red diffused venous strands. These spots are mostly caused by the imbibi- tion of serum, which has taken up the coloring matter of the red corpuscles of the blood, into the walls of the vessels, and, through these, immediately into the sur- rounding cellular tissue. All these signs become first visible on the posterior wall, where they are, in part, caused by hypostasis; soon, however, they appear also on the anterior wall. At the same time, similar blood- red venous strands are formed at the lesser curvature. These alterations are of great importance in doubtful cases of poisoning. Caspar says that the signs which many writers have described as blood stases, and even as traces of inflammation, and which they have desig- nated as the signs of death from suffocation by hanging or drowning, are nothing but the signs of early decom- position here enumerated. As the process of decompos- ition continues, the discoloration of the stomach changes from dirty red to greyish-black and the membranes gradually succumb to the softening process, which, how- ever, progresses at the same rate in all other membranes. In not a single case has Caspar noticed, as a mere pro- duct of decomposition, the detachment of the mucous membrane from the muscular tissue, which occurs as the effect of corrosive poisons which must not be confound ed with the merely emphysematic loosening of the mucosa. Still, in a very few cases, an excoriation of the mucous membrane may be caused by the bursting of a blister of decomposition, but then the base of the blister and its surroundings will be colored, and the existence of other blisters of decomposition, not ruptured, will insure a correct diagnosis. - & 4. Next in order are the intestines, and all that has been said with regard to the stomach, applies to the re- maining portion of the alimentary canal. The coloring caused by exosmosis, in the intestines near the gall blad- der, known even to those who have made but few autop- sies, can deceive no one. But the hypostatic coloring of the intestinal loops, which occurs early, and is espec- ially visible in the loops taken up from the small pelvis, may easily give rise to mistakes. During the course of decomposition the intestines become dark brown, they burst, pour out their contents, become greasy, and are, finally, converted into a shapeless dark paste. In one case, where a corpse had been exhumed, that showed no trace of any of the organs of the thorax, Caspar found fresh feces in what appeared to be an intestinal loop which had preserved the distinctive odor of human faces, - 5. In the majority of cases, the spleen is preserved longer than the stomach and alimentary canal. Still it belongs to the class of organs that are attacked at an early date. It becomes soft and, gradually, jelly-like, may be readily crushed, and after decomposition has progressed still further it becomes of a steel blue green º ; Soft, that it can be scraped off with the handle of 8, KIllie. 6. The omenta and mesenteries withstand decomposi- tion a little longer. If they are very lean, they may be in a good state of preservation for several weeks after death; but if full of fat they decompose early. They become of a greyish-green color, and dry. These organs do not readily occasion errors. 7. In ordinary cases, the liver is found solid and firm for a few weeks after death. In neo-nati, however, it is attacked sooner than in adults. Decomposition appears first on the convex side, in a glittering green color which subsequently covers the entire organ, until it is changed into a coal black. As in all organs, a portion of its blood evaporates at the same rate, and the parenchyma is gradually turned into a jelly-like mass. But if the gall bladder contains no bile (which exudes or evaporates), it collapses. 8. The substance of the brain of adults is the last in order of the series of organs that decompose early. The brain collapses immediately after death, and this con- tinues as decomposition progress. Remarkable as it is the first traces of decomposition do not appear on the surface, but at the base of the cerebrum, in a light green color which extends from below upwards, and, gradually, over the entire brain. It visibly progresses from the grey substance to the white. In a moderate tempera- ture the brain softens in from 2 to 3 weeks, but it takes months before the brain of adults becomes that reddish mass, into which the brain of neo-nati is so very soon converted. A wounded brain, like all wounded organs, owing to the increased access of air decomposes much more rapidly. This circumstance may impede a thor- ough examination of penetrating injuries to the head, 9. The heart is the first of the series of organs that decompose at a later date. When the stomach, intestines, liver, etc., have for weeks been in a state of decomposi- tion, the heart is still fresh and distinct in all its parts, though flat and collapsed, containing at that time, gen- erally no blood at all, or only a few remnants of greasy blood. Generally the heart softens: its color is at first greenish, subsequently greyish-green, and finally black. The little quantity of liquor pericardii evaporates after decomposition has progressed but very little, and the pericardium becomes quite dry. Still, the heart does not show this high degree of decomposition until several months after death. - 10. The lungs show the effects of decomposition about simultaneously with the heart, sometimes sooner. In corpses that exteriorly present the higher degrees of de- composition, such as a green color, excoriation of the epidermis, etc., the lungs are frequently still so well pre- served that their structure may be distinctly recognised. This indisputable fact says Caspar, is an important answer to the objections made by theorists, to the hy- drostatic test. For if the lungs of a new born child, whose corpse is still fresh, or shows only the first signs of decomposition, such as a greenish color of the walls of the abdomen, floats on water, we cannot, in the light of experience, assume, that they do so because gases of 174 [APR. 13, 1872. T EH. H. CT, IISTIC. decomposition have developed and made them specifi- cally lighter than water. The lungs do not decompose Bo soon after death, extremely rare cases only excepted. Moreover, decomposition of the lungs cannot be mis- taken. Its first traces appear in the shape of circum- scribed spots of a pale red color and the size of a pin's head up to that of a millet-seed on the surface of the lungs. They are caused by a circumscrihed raising of the pleura, or the filling of one or more peripheric lung cells with gas. An incision shows at once the fact that this accumulation of gas does not penetrate to the par- enchyma. These early traces of decomposition of the lungs, in corpses otherwise still fresh, are not at all rare, whilst the higher degrees of decomposition of the lungs in such corpses are, as before stated, extremely rare. In such cases, too, decomposition shows itself in blis- ters varying in size from a millet-seed to a bean caused by an accumulation of a gas below the pleura and can be so easily recognised, that they are in themselves a very plain diagnostic sign of decomposition leading us without difficulty to ascribe the floating of the lungs to their putrescent condition. These blisters are first single and in the most different portions of the lungs. Subse- sequently they increase in number so as to closely cover entire portions, especially the inferior surface of both lungs. - Notwithstanding the development of these blisters the lungs do not, at first, change their color. In the course of decomposition the color becomes darker, dark green and finally black, and the destruction of the parenchyma keeps even pace with this discoloration. The lungs| soften, the evaporation of the liquids causes them to collapse, and at last, they are entirely destroyed. 11. The kidneys follow next. Their color turns brown; afterwards they begin to soften, whilst their granulated texture can still be recognised, and not until long after death are they found greasy, of little consistency, and of a black and green color. - 12. The bladder, whether empty, or partly or entirely filled, shows no signs of decomposition until all the organs enumerated have been attacked. 13. The aesophagus does not, in the process of decom- position, keep even pace with the rest of the alimentary canal. When stomach and intestines can no longer be critically examined, it will be found for months, still pretty tense, though of a dirty greenish color. 14. A pancreas, showing signs of decomposition, can be found only in a corpse entirely deeomposed. Its color turns a dirty red, until it finally suecumbs to gen- eral destruction. 15. The diaphragm decomposes very late. Though in the first weeks after death green spots make their appearance, still its muscular and aponeurotic structures may be clearly distinguished in corpses four to six months after death. 16. Small bloodvessels running into putrescent organs are withdrawn from observation; but the larger vessels, especially the arteries, are of all the soft parts among the very last to succumb to destruction. 17. To the uterus, Caspar vindicates (against Orfila) the greatest resistance to decomposition of all the soft parts. When not a single other organ ean any longer be examined it is still found entire in its position pretty fresh and dense, of a dirty red color, and so well pre- served that we may cut it open and examine its interior. To show the importance of this fact; Caspar” cites at great length, a case in point from which we abstract the principal items. A young servant girl suddenly disap- peared. Rumor would have it that she was enceinte, as the result of a liaison with a married man of previously unsullied reputation. Nine months later her body was found in the privy of the house where she had lived. Skull, lower jaw and the greater portion of the lower extremities had by maceration been deprived of the soft parts; the joints were partly loosened, and whatever there was left of the soft parts was nothing but stinking black remnants. The muscles of the abdomen had changed to adipocire; the intestines, liver, spleen and kidneys had become a black greasy mass. And yet Caspar found the uterus entire, of a light red color, hard and firm to the touch and under the knife, of normal virginal size; its cavity empty. He concluded, of course, that the deceased at the time of her death could not have been enceinte. - - Cincinnati, March, 1872. HENRY HAACKE. —-º-º-º- screNTIFIC NoTEs. Extracts from Quetelet’s Contributions to the science of Mºſarn. To Quetelet is due the argument from the astonish- ing regularity from year to year in the recurrences of murders and Suicides, a regularity extending even to the means or instruments by which these violent acts are committed; his inference being broadly “that it is society which prepares the crime, the criminal being only the instrument which executes it.” To quote a luminous instance of this regularity of action, M. Quetelet gives a table of the ages of marriage in Belgium (Phys. Soc. i. p. 275). Here the numbers of what may be called normal marriages, those between men under 45 with women under 30, as well as of the less usual unions where the women are between 30 and 45, show the sort of general regularity which no one would expect from mere consideration of the circumstances. The astonishing feature of the table is the regularity of the unusual marriages. Disregarding decimals, and calculating the approximate whole numbers in their proportion to 10,000 marriages, the table shows in each of five five-year periods from 1841 to 1865, 6 men aged from 30 to 45 who married women aged 60 or more, and 1 to 2 men aged 30 or less who married women aged 60 or more. M. Quetelet may well speak of this as the * Caspar's Gerichtl. Med. 5. Aufl. II. Berlin, 1871. APR. 18, 1872.] T EH. H. C. T., T N T C - 175 most curious and suggestive statistical document he has met with. These young husbands had their liberty of choice, yet their sexagenarian brides brought them up one after the other in periodical succession, as sacrifices to the occult tendencies of the social system. The statistician’s comment is, “It is curious to see man, proudly entitling himself King of Nature and fancying himself controlling all things by his free will, yet sub- mitting unknown to himself, more rigorously than any other being in creation, to the laws he is under subjec- tion to. These laws are co-ordained with such wisdom that they even escape his attention.” “ * * It is well known in current opinion that more children are born in the night than in the day; in fact, there are about five night-born against four day-born, the maximum being about mid-night, the minimum a little before noon (i. p. 208). Why this is no one yet knows; it is a case of unexplained law. But another not less curious law relating to births seems to have been at last successfully unravelled. In Europe about 106 boys are born to every 100 girls. The explanation appears to depend on the husband being older than the wife; which difference again is regulated by prudential considera- tions, a man not marrying till he can maintain a wife. In connection with this argument it must be noticed that illegitimate births show a much less excess of male children (p. 168). be accepted), it appears that a law which has been supposed to be due to purely physiological causes is traceable to an ultimate origin in political economy. The examples brought forward by Quetelet, which thus show the intimate relation between biological and ethical phenomena, should be pondered by all who take an interest in that great agent of our time—the intoduc- tion of scientific evidence into problems over which theologians and moralists have long claimed exclusive jurisdiction. This scientific invasion consists mainly in application of exact evidence, in place of inexact evidence and of proof in place of sentiment and authority. Already the result of introduction of statistics into in- quiries of this kind appears in new adjustments of the frontier line between right and wrong, as measured under our modern social conditions. Take, for instance, the case of foundling hospitals, which provide a “tour,” or other means for the secret reception of infants aban- doned by their parents. It has seemed and still seems to many estimable persons an act of benevolence to found and maintain such institutions. But when their opera. tion comes to be studied by statisticians, they are fonnd to produce an énormous increase in the number of ex- posed illegitimate children (Phys. Soc. i. 384). In fact, thus to faciliate the safe, the secret abandonment of children is to set a powerful engine at work to demoral- ise society. Here, then, a particular class of charitable actions has been removed, by the statistical study of its effects, from the category of virtuous into that of vicious actions. And even more important transition of the same is taking place in the estimation of almsgiving Here, then (if this explanation may from the ethical point of view. Until modern ages, through all the countries of higher civilisation, men have been urged by their teachers of morality to give to the poor, worthy or unworthy; the state of public opinion being well exemplified by the narrowing of the word “charity” from its original sense to denote the distribu- tion of doles. Yet, when the statistics of pauperism were collected and studied, it was shown that indiscrim- inate almsgiving is an action rather evil than good, its tendency being not only to maintain, but actually to produce idle and miserable paupers. In our time a large proportion of the public and private funds distrib- uted among the poor is spent in actually diminishing their industry, frugality, and self reliance. Yet the evil of indiscriminate almsgiving is diminishing under the influence of sounder knowledge of social laws, and genuine charity is more and more directed by careful study of the means by which wealth may be spent for the distinct benefit of Society. Such examples as these show clearly the imperfection and untrustworthiness of traditional, or what is called intuitive morality, in deciding on questions of right and wrong, and the neces- sity of appealing in all cases to the best attainable in- formation of social Science to decide what actions are really for or against the general good, and are therefore to be classed as virtuous or vicious.--Nature, Mar. 7, '72. —º-º-º- Sea-Sickness. Sir, Recent, though not large, experience emboldens me to make one or two comments on the ingenious theory of sea-sickness, supported by Sir James Alderson in your last number. Mechanical theories succeed completely or not at all. If sea-sickness were due to the impact of the mass of blood within the body on the brain in its quasi-rigid coverings, or rather, as Sir James Alderson rightly says, of the brain and its coverings on the mass of blood, then every person who lay down flat with his head to the bows would escape sea-sickness; which, so far as my ex- perience goes, is not the case. Undoubtedly the hori- zontal position, with the head low and the eyes shut, offers the best prospect of escape from the malady; but I have never seen any reason to attribute the result to the direction of the head. The feeling of dissociation between one’s solid and fluid component parts—as if they found a difficulty in keeping pace with one another in the race of floating up and down with the ship—must be only too familiar to landsmen. The focus of discomfort appears to be not the brain but the Solar plexus. A feeling of distress at this point is the instantaneous accompaniment of every lurch, whether vomiting occur or not. That no such sensation follows a degree of concussion of the brain sufficient to produce violent vomiting, I can personally testify; if, indeed, recollection in such a case be worth anything. 176 [APR. 13, 1872. T EH. H. c T.I.N.T. c. Again, if the cause were so purely mechanical and simple, all persons ought to suffer in proportion to the patency of their vascular systems, which I have not observed to be the case. And the remedy ought to be equally simple, namely, pressure by a pair of pads on the carotids during the descent of the portion of deck occupied by the traveler. A lever attached to a small parachute would easily effect this. The same plan might be applied to waltzers, by an adaptation of the arrangement called the governor of a steam-engine. Landsmen who repeat their voyages only at consider- able intervals ought not, if this explanation be the right one, to gain any immunity from the repetition ; whereas, in most cases, they do gain a certain degree of immu- nity. And the recovery of all on board, after two or three days at Sea, ought to be due to an alteration in the mechanical conditions of their cerebral circulation ; a proposition which it would be difficult to prove. I need hardly say that these remarks are not prompted by want of respect for the authority of the accomplished writer to whose paper they refer. I merely suggest that the demonstration would be more complete if these points were noticed. If a channel ferry scheme had occurred to Dante, he would doubtless have added another depth to his Inferno, in which the offender, immured in a railway carriage lined with frowzy cloth padding, with closed windows, should make perpetually the sea and land journey be- tween London and Paris in the company of five of our volatile neighbors.-Mayo, Brit. Med. Journ., Mar. the crown. 23, '72. —º-e—º- |PROF. LAY COCIR ON EARS : H, obed and Lobeless Ears; Monkey Ears; Roger Tichborne's and “The Claimant’s” Ears. From the London Med. Times and Gazette, Mar 16, ’71" In the Medical Times and Gazette for Mar. 22, 1862, appears a lecture by Professor Laycock on the coexistence of weakness or defective organ- isation of the brain, with certain peculiarities of formation of the face, and especially of the parts answering to the “ribs” of the cranial vertebrae. For instance, congenital defect of the brain and tendency to tubercular or other tissue-degeneration are so often associ- ated with a defective and receding chin that artists and novelists, when they wish to describe aperson of unusual strength of character, are sure to give him a well developed square-cut chin. An upper jaw contracted from side to side, with a very narrow and highly arched palate; the “rabbit jaws” with upper teeth projecting so that they cannot be covered by the lips; peg-like deformity of the upper lateral incisors; imperfect development of the * * • * , s • * . • ‘’ s • . . " upper lip, and going so far as hair lip and cleft palate; and noses, either snubbed and turned up, showing the cavities of the nostrils, or preternaturally big and saus- age-like, as in the Aztecs, are all familiar examples, But we wish to recall attention especially to Professor Laycock's remarks on the ears, for they refer by antici- pation to the difference between the ears of Roger Tichbourn and those of the “Claimant” who is now awaiting his trial for perjury. - r “The form,” says Professor Laycock, “of the external ear depends upon two fundamental elements—namely, first, the cartilage with its muscles; secondly, the helix and lobule. In man the cartilage of the perfect ear is comprised within an ellipse or ellipsoid proportionate to the head, and to this is attached a geometrically-formed helix and a pendent ellipsoid lobule. In proportion as these parts are defective, or as the ear is monstrous, triangular, Square, or of irregular form, it indicates a ten- | dency to cerebral degeneration or defect. Monstrous ears, with defective helix or lobules, are very common in idiots and imbeciles. You will note the defective form and absence of lobule in the female Aztec and in the case of dementia. The ear of the male Aztec cretin is also defective, but it more nearly resembles the ear of the chimpanzee. * “Angle of Position of the Ear.—You will find that the |ears of persons differ much as to the angle of position on the head. The ear points either backwards towards the vertex of the head, as in the chimpanzee, or upwards to Ears pointing backwards are usually defec- tive in form and development of parts, as the helix or lobule. ę “Modifications of the Helia, and Lobule.—Race has, I think, an influence on the development of the external ear, although I speak with reserve, not having had nu- merous opportunities for observing and comparing. But, so far as I have had them, I conclude that the ear in colored races more nearly approximates that of the chimpanzee than in our Anglo-Saxon race, in which the helix is full and the lobule large and pendent as com- pared with men of the darker races that I have seen, whether African or Malay. Sea, has certainly an in- fluence, for it appears to me that women generally have not only the whole ear smaller than men, but the helix and lobule smaller in proportion to the ear. And Ithink I may venture to say, as the result of numerous examin- ations of the ears of female lunatics and imbeciles, that from one-third to one-fourth are below the standard of development as to the lobule. In men somewhat feminine in form, and compartively defective in force of character, the ears are often feminine as to the helia and lobule. You may have such men manifesting great refinement and sensibility, and perhaps considerable intellectual power; but, at the same time, even with marks of genius, there is often seen less capability of endurance mentally, less force of character, less tenacity of purpose, and even less clearness of ideas than in standard men. t “Men of high intellectual attainments, great capacit APR. 18, 1872.] TIH. H. C.L.INI c. 177 for mental labor, and great force of character, have a full perfectly ovoid ear, the helix well developed, the lobule plump, pendent, and unattached to the cheek at its an= terior margin. These characteristics are seen in all the portraits of great men which Lavater gives, and are easily observed in living celebrities. I was much struck with the highly characteristic ear in these respects of the Prince Consort, as he stood without his hat when laying the foundation-stone of our Industrial Museum in October. . . - * “Activity of the instincts and appetites, and perhaps of vegetative or nutrient force in general, seems also to coincide with a well-developed lobule. It is worthy of remembrance that these parts are not constituted wholly of cartilage; the helix is cartilage covered with a layer of condensed cellular and adipose tissue, but the lobule is made up wholly ofcondensed cellular and adipose tissue without any cartilage whatever. This layer and the skin || covering it are highly vascular. Now, in proportion as the helix is simply cartilaginous and the lobule defective, or, in other words, as this vascular elastic tissue is want" ing, you seem to have imperfect encephalic action and development. And with certain reservations, the plump- ness and vascularity of the lobules may be considered to coincide with common activities within the encephalaon. I say within the encephalon because I am satisfied we must not restrict our consideration of the question to intellectual activity alone, for that implies only activity of a certain kind. You may have great volitional activity, as in the day laborer, or great sensual activity as in the sensualist, who seeks only the indul- gence of his appetites, whether sexual or others. But it is further to be noted that this vascular activity may be wholly local and due to exclusively local causes, as constant exposure to the atmosphere. “Defective and Adherent Lobule.—In a perfect ear the ovoid lobule hangs from the cartilage with a rounded lower margin, which at its inner border is not confluent | with the face. Now, if this inner margin be adherent to the cheek, and at the same time the lobule be only a segment of an ellipse, there is more or less tendency to imperfect cerebral action. A more important form is seen when the lobe is not only soldered to the dheek, but its posterior half cut away, as it were, and the helix defective.” t - - The significance of Professor Laycock's remarks is obvious. Roger. Tichbourn had a soldered and ill- developed lobule. This was quite consistent with his whole character and person—overbred, not well- developed, and, undersized. On the other hand, the well-developed lobule of the Wagga-Wagga slaughter- man seems consistent with his audacity, strength of purpose, and power of will. That one condition can be changed into the other we hold to be incredible. VENTRAL BODY HEAT—Animals preserve their tem- perature best in abdominal decubitus or in crouched positions in which the belly is covered by the ground or by the extremities. If rabbits be left bound upon their backs with extended limbs, as in the position for experi- mentation, in a room of usual temperature (13–15 C.) they continue to cool off to such extent that death en- sues in from one-half to one day. This loss of heat is not caused by the fastenings for if the animal be abundantly covered with wool or some such protection it does not occur. Man, too, gives off a much greater quantity of heat from the ventral than from the dorsal surface as is easily verified by the more marked chilliness experienced in a cold room in bed under light covers when decubitus is on the back than when partly or en- tirely on the belly or even with flexed limbs. The reason of this greater radiation from the ventral surface is certainly due to the fact that the viscera are covered anteriorly with a much lighter layer of muscle, etc.— Ackerman,—Berlin. Klin. Wochenschr, Jan. 15, 72. —-º-e—sº- MEDICAL NEws AMERICAN MEDICAL Association. WM. B. ATKINSON, M. D., Permanent Secretary, 1400 Pine Street, Southwest cor. Broad, Philadelphia. The Twenty-third Annual Session will be held in HoRTICULTURAL HALL, Philadelphia, Broad Street above Spruce, on Tuesday, May 7, 1872, at 11 A. M. HOTEL ARRANGEMENTS. Continental, Chestnut and 9th, $4 a day Girard, Chestnut and 9th, $3 a day. La Pierre, Broad below Chestnut, $3 a day. Colonnade, Chestnut and 15th, $3 a day. St. Cloud, Arch below 8th, $3 a day. St. Elmo, Arch above 3d, $2 50 a day. American, Chestnut below 6th, $2.50 a day. Merchants, 4th above Market, $2.50 a day. St. Lawrence, Chestnut below 12th, $2 a day. Alleghany, Market below 9th, $1.75 a day. St. Charles, 3d bel. Arch, lodging only, 50 cts. a day. Miller's, 7th and Chestnut, lodging only, $150 a day. Meals at restaurant of Horticultural Hall, and Petry’s, N.W. cor. Broad and Walnut, each 50 cts. RAILROADS. All the Railroads have agreed to issue half fare, excur- sion or return free tickets. Bay All who desire to avail themselves of the above rates, must send to the Secretary their full names, and the names of all the railroads over which they must travel in coming to the session, with stamp for postage. - WM. B. ATKINSON. SPECIAL. Camden and Amboy, excursion tickets at $4 from New York to Philadelphia and return, if fifty tickets 178 * [APR. 13, 1872. TIEEE E C T.I. N. T. C. are taken. For this ticket, send money to Dr. A. E. M. Purdy, 123 East Thirteenth Street, New York. From Washington to Philadelphia and return, $6 if|P fifty tickets are taken. Central Pacific, half local rates, —-º-c-ºn- KENTUCKY STATE MIEDICAL SOCHETY Transactions of the Annual Congress of ’72. The Kentucky State Society closed its sessions April 4, at Louisville where it had convened for the annual con- vention of ’72. - - The first part of the session was occupied by a question of medical ethics; Dr. E. S. Gaillard having preferred a number of charges against the private and professional character of Dr. David W. Yandell. After considerable debate the subject was decided out of order. An ap- peal from this decision not having been sustained, the charges were withdrawn. Dr. T. N. Wise, (Covington), the President of the association then delivered the annual address. The subjects upon which the speaker dwelt were the necessi- ties of the legalisation of dissection, of enactments to secure efficiency in the dispensation of medicines, the registration of births, marriages and deaths, and quite extensively upon medical education. As the speakers views are somewhat at variance with those usually pro- pounded on such occasions we take the liberty of making the following extracts: “There is, gentlemen, an undeniable connection between the age of a government—between the popular character and genius of the people—and all of the pub- lic, literary and scientific, institutions which such a peo- may originate, develop and support. Illustration is useless. History, with her magic pen, has given us endless illustrations. of the Government and the genius of the people are chiefly scientific and military; in France they are characterized by self devotion, impulse and enthusiasm: in England they are conservative, aristocratic and thorough; in Scotland, Scholastic, accurate and analytical, in America, practical, rapidly changing, strongly marked by an easy and swift adaptation of forces to the results which are to be accomplished. These undeniable facts are due to the wonderful construction of the human mind, which, among its endless glories, numbers that special glory which is beyond all description and praise —the faculty of adapting the individual to the sphere in which he is to move, to the habits, customs and the necessities of those who surround him ; to those great differences of thought, perception and action which characterize each and all of the nations of the earth, and which in the aggregate have given them individuality | and a separate history. All institutions, then, of every people, in order to be permanent, must be adapted to the people who surround such institutions, and who are to give it its permanency, success and glory. If this be the case—if the lessons of history be not pointless—foolish fables—how vain, how foolish it is to expect that the medical institutions of America are to be conformed to those of other nations, rather than to the genius of the people, who are to give to each institution a local habi- Thus in Germany, the character | tation, a reputation and a name? How illogical is it, therefore, for us to expect that our medical institutions, eculiar to a peculiar people, should conform to institu- tions which have originated and been sustained by na- tions differing entirely from our own in age, genius, demands and characteristics. • . Let us not, therefore, seek after strange gods—let us venerate and protect our own.” - We have space but to notice a few of the papers pre- sented. - - Dr. Fraze read a paper on the Kentucky. - - Dr. L. P. Yandell, Jr., reported cases of epilepsy in which blueness of the skin, resulting from the use of nitrate of silver, was removed by the use of nitrate of potash. He also reported a case of parasitic disease, known as favus, the parasites being the effect and not the cause of the disease. Also, a singular case of vesi- cular disease. - - - - - A paper of Dr. J. W. Clemens on apparatus for trans- verse fracture was referred to the Committee on Publi- cation. - - Dr. J. J. Speed read a paper on Phthisis, which was referred to the Committee on Publication with direc- tions to publish it. - º Dr. D. W. Yandell read a paper on epilepsy treated with bromide of potassium and sulphate of atropia. Papers by Dr. D. T. Smith and Dr. C. T. Ulrich were referred to the Committee on Publication. Mineral Waters of 3. - The following special committees were appointed: Registration—Dr. Jno. D. Jackson, Danville, Chair- man. - Publication—Drs. Jno. Goodman, T. P. Satterwhite, and S. Brandeis. - - - Medical Electricity—Prof. J. W. Holland. - Recent Improvements in Ophthalmic Surgery—Dr. D. S. Reynolds. - - - - The President was chosen a delegate to the American Medical Association, which meets in Philadelphia next month, and was authorized to appoint the other dele- gates. - . . . The following honorary members were elected, and the Corresponding Secretary was requested to notify them of the fact: Drs. J. J. Woodward, Washington City, D. C.; E. Williams and Wm. Carter, Cincinnati. The Committee on Nominations reported the follow- ing officers, who were duly elected: - For President—Dr.Lewis Rogers, Louisville. Senior Vice President—Dr. Jas. W. Thompson, Pa- ducah. - - - Junior Vice President—Dr. Joseph Smith, Lexington. Recording Secretary—Dr. J. A. Larrabee, Louisville. Treasurer–Dr. L. B. Tood, Lexington. - Corresponding. Secretary—Dr. W. T. Humphreys, Louisville. - - Committee on . Publication—Drs. John Goodman, S. Brandeis and T. P. Satterwhite, Louisville. Librarian—Dr. R. H. Thornton, Newport. On motion, the thanks of the Society were tendered APR. 13, 1872.] 179 to the President, Dr. T. N. Wise, for the efficient and impartial manner in which he had fulfilled the duties of his office. - . - The usual thanks to the railroads, physicians of Louisville and others for courtesies extended were then passed, and the meeting adjourned. The next session of the society will be held in Paducah on the first Tuesday in April, 1873. SIGNS OF THE TIMES.–The last number of the N. Y. Medical Record contains as its leading paper a ten- paged article on the “Pathogeny of Pyaamia and Septi- caemia” by Mary C. Putnam, M. D. - PROMOTION of TRAUBE.—Privy Counciller Traube of Berlin has been promoted to the position of professor in ordinary at the University of Berlin. The prejudice of the minister of education against Jews alone preven- ted this promotion long since. Prof. Traube is the first individual of Jewish faith ever promoted to this position in Berlin. - Dr. Rosenthal, also an Israelite, has accepted the proferred chair of Physiology at Erlangen. MEDICAL SCIENCE IN QUITO.-One of the last trav- ellers to the Andes, Mr. Orton, whose notes on the phys- ical structure of that part of the world are exceedingly valuable, and whose observations on the Social status of the people are reliable, mentions the curious fact that there are only three drug stores in the great city of the Incas, and the sign which indicates the business is a serpent. Physicians there have no offices, and rarely visit patients at their dwellings. When a sick person | is too sick to call upon the doctor, it is considered a hopeless case. - - - Yellow fever and consumption are unknown in Quito. Catarrhal affections and typhoid fevers are common. Asthma, however, is exceedingly prevalent, and there- fore such altitudes as are made the abodes of moun- taineers in Peru should be carefully avoided. CUSTOMS AND SALARIES OF PHYSICIANS BEFORE THE CHRISTIAN ERA.—Boerhaave observes that before there were any professed physicians, it was the custom among the ancient Egyptians, when any one was sick, to inquire of neighbors and passengers if they knew of any proper remedies for the patient. But eyer since the study of physic became a profession, it has been both honorable and lucrative. The customary yearly salary which princes paid their physicians, about the time of Christ's birth, was 250 sestertia, or above 2018!, sterling. Stertenius complained that he had only a salary of 500 sestertia, or 4036!. 9s. 2d. Sterling, when he had by his private practice 600 sestertia, or 4848l. 158.--Dr. Arbuthnot's Book on Coin, and Mr. William Smith's Book of Remarks on the same subject. MUNIFICENT DONATION.—The Middlesex Hospital has received another sum of £20,000. It may be re- membered that a like sum was given by an anonymous donor to the Hospital two or three years ago. Last year the name of the munificent benefactor—Mr. Francis Brodrip—was made public. The second sufn of £20,000 now handed over to the authorities of the Hospital, is the proceeds of the sale of Mr. Brodrip's pictures and other works of art, which he directed to be disposed of |after his death for the benefit of the Middlesex Hospital. —Brit. Med. Journ., Mar. 23, '72. A HEAVILY BACKED JOURNAL.—A New Journal of Ophthalmology has been started in Paris. Its cover bears the names and titles in full of two directors, fifteen editors in chief, including the directors, and thirteen corresponding editors. FRENCH PATRIOTISM.–A committee of women, all wives of physicians, has been organized in Paris to assist in the liquidation of the national debt. The internes of the Lyons Hospitals have all given up a months salary for the same purpose. THE OLDEST MEDICAL COLLEGE IN THE WEST.-The last number of the St. Louis Medical and Surgical Jour- nal, (April, '72), prefaces the report of the commence- ment exercises of the Missouri Medical College with the statement that this Institution is the oldest Medical College in the West. ! We have before us the U. S. official table of statistics of all the “Medical, Dental and Pharmaceutical Institu- tions in the United States.” Western medical colleges take place in the order of age as follows: Medical College of Ohio, tº tº 1819. “ “ “ S. Carolina, - - 1824. “ Dept. Univ. Virginia, - - 1825. “ Coll. Georgia, tº- - - 1832. “ Dept. Univ. Louisana, - 1836. {{ & C “ Louisville, - - 1837. Missouri Medical College, - - IS40. As our friend Dr. McIlvaine used to say, “There's nothing like having your dates correct.” —º-º-º- Graduates in Medicine in 1872. Bellevue Hospital Medical College 129 Jefferson Medical College ... 114 Ohio Medical College 90 Medical College of Nashville 84 University of Pennsylvania a 83 College of Physicians and Surgeons, N. Y. 78 Rush Medical College (Chicago) 77 University of the City of New York . - 75 Miami Medical College * - 67 Med. Dep. University of Buffalo . 34 Cleveland Medical College, Ohio 34 Med. Dep. of Georgetown College 20 Medical College of Virginia . º & 12' National Medical College (Washington) . . 7 —News and Library, Ppril, '72. 180 [APR. 13, 1872. TEEE CI.INI c. CLINICAL MEMORANIDA, The Treatment of Variees by the Subcutaneous Injection of Ergot. BY DR. PAUL Vogt (Griefswald). Assistant at the Surgical Clinic and Private Docent at the University of Griefswald. From the Berlin. Klin. Wochenschr., Mar. 4, '72. The observations of W. Langenbeck on the cure of two cases of aneurism by the subcutaneous injection of ergotin (Berl. Klin. Wochenschr., 1860, No. 12, p. 117) and the further report of cure in a case of aneurism of the femoral artery by Schneider (Session of the Society of Scientific Medicine, Königsberg, May 25th, 1869) and finally the cure of an aneurism of the subclavian by Dutoit (v. Langenbeck's Archiv. Bd. xii) would seem to have established the effects of ergot preparations upon the blood-vessels. Dresche of Vienna, moreover, was the first to adopt this principle in the treatment of hemoptysis by the subcutaneous injection of ergotin (Centralblatt f. Med. Wissenschaft., 1868, No. 52). Last summer I commenced some experiments with a view of determining the effects of ergotin in other dis- eases of the vessels, examining more especially into its influence upon that affection which in the existing state of our knowledge, so far as radical cure is con- cerned, is almost hopeless. I refer to varicosities of the veins of the leg. Since the principle of radical cure of these varices hitherto—the obliteration of the veins by one method or another in a greater or less extent of surface—involved such dangers and discomforts as to be out of all proportion to the original disease, we have been limited essentially in our Selection of innocuous methods of treatment, to a therapy only palliative. With a view of regulating the circulation and of re- lieving the stasis and ectasia I made some experiments with ergotin. In the case of a man aged 60 who had suffered for years with extensive varcies of the right leg I injected beneath the skin of the leg an aqueous solution of extr Secal. cornut. 2.0 grm. with spirit vini and glycerin. aa 7.5, selecting two particularly marked dilatations as the seat of injection. An enlarged vein 6 ctm. long, running diagonally over the tibia was marked on its borders with a pencil of lunar caustic and over it was injected subcutaneously a whole syringe full of the solution (0.12 ergotine). This was repeated every 2 days. After eight days there was nothing to be seen of the varix and after six weeks, during which time the patient walked about as usual, there was no trace of it to be seen or felt. A second varix of haselnut size on the outside of the calf disappeared in like manner after a single injection of ergotine. At the points of injection by it in the pulse. there appeared a hard somewhat circumscribed infiltra- tion which, however, in the thin and atrophic skin of the Senile individual mentioned gave rise to no inflammation nor gangrene, disappeared gradually, on the contrary, without having excited any marked pain. For the further examination into the effect of ergotine upon the vessels I induced Dr. Potel to undertake two investigation. 1, to examine into the action of ergotine | upon the vessels of the mesentery of the frog. 2, to in- yestigate with the sphygmograph, the changes induced - Under the direction of Prof. Lan- dois the microscopic and sphymographic effects of ergot upon the muscular coat of the vessels, both arterial and venous, were demonstrated (see his Inaugural Disserta- tion, Griefswald, 1871.). Thereupon the subcutaneous injection of ergotin in the manner mentioned was re- peated upon different patients with varices of the leg in our surgical clinic and dispensary and even in the cases of ºl ectasias was the happy effect surprisingly rapid. MANAGEMENT OF EPILEPSY-Dr. Brown-Séquard recommends, in the treatment of epilepsy, the following combination of the bromides of ammonium and potas. Slti DOl Potassi iodidi. dr. j. Potass. bicarb, scr. iſ. Potassi bromidi, oz. j. Ammonii bromidi, dr. iiss. Inf columbaº, oz. ºff. . S.—A teaspoonful before each of the three meals, and three teaspoonsful at bedtime, with a little water. Dr. Roberts Bartholow's (Fisk Fund Prize Essay) plan of treatment consists in giving a powder, contain- ing two scruples of bromide of potassium dissolved in water, three times a day, and after the cessation of the paroxysms a drachm dose at bed time only. It is now well known that a patient cannot omit his dose for a single day without danger of having the attacks return, and he cannot be considered exempt until he has passed two years without a convulsive seizure. To prevent the development of bromism Brown- Séquard is in the habit of combining arsenic with the bromide of potassium. Since using this combination, he has not observed so much the debility caused by its prolonged administration. The use of iron, strychnia, the hypophosphites, is also indicated to maintain the health of epileptics during a course of bromide of potas- sium. The hygienical means consists of abundant food, wine, out-door employment, and a careful regulation of the moral life.—N. Y. Medical Record.—Georgia Med. Companion, Mar., '72. - —º-e-C*- IHIOM IE NEWS. PROF. BROWN-SíquaRD will enjoy his lune de miel in Paris whither groom and bride have already departed. Cambridge, Mass., it is stated, will be his new and per- manent field of labor on his return. THE ACADEMY has reconsidered its previous vote so as to permit an abstract of the proceedings of the pre- vious session to appear regularly in every issue of THE CLINIC. As our home subscription and foreign exchange lists are now quite extensive, the passage of the present law is a subject of mutual congratulation. & Sº & sº Yº - S. 2". "...sº Sºzº º Sº T. . . ºº Sº º ſº º-º $º . . . . § sº jº º . . º. . . ** Ille, JAMES FOSTER, JR., & Co. Instrument Makers and Practical Opticians, Beg leave to return thanks for the patronage extended to them through a long series of years (having been established since 1836), and in the reorganization of their firm will endeavor to merit a continuation of the game. We wish it understood by the Profession and the Public generally that our invariable rule is, to make or import none but the best in. struments. Those in want of any of the acknowledged good aids of vision to imperfect eyes, will always find the best and largest stock of Lenses, Spectacles, and the best models procurable, with pains- taking skill to adjust them to all conditions of sight, at our house. Special attention paid to orders for Fine Microscopic Objects and Microscopic Apparatus, Magnifiers and Readers in great variety. Medical Batteries, Barometers, Thermo- meters, Hygrometers, Urinometers and Rain Gauges, of the most approved constraction always on hand. All orders promptly t and accurately filled. JAS. FOSTER, JR. & F. S. SHAößEroRD, : ** JAs. Foster, J.R. & Co. S. W. Cor. Fifth & Race Sts., Cincinnati, 0. TR.s.IN.INMARSH's ‘gº) TRUSSES sº-º: No. 758 BRoadway, New Yoak I HAVE been in the habit of applying and recommending the Truss manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined. LEWIS A. SAYRE, M. D. Surgeon, Bellevue Hospital. Q. From Prof. Willard Parker to S. D. Townsend, M. D., Surgeon to the Massachusetts General Hospital. BRG leave to state for the benefit of all concerned, that I have known Dr. S. N. Marsh the last fifteen years. * * I am in the constant habit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with any of the risks to the patient, that exist in many of the plans suggested and attempted to be carried into execution. I have confidence in Dr. Marsh as a gentleman of honor and integrity, and as such recommend him to the members of the medi- cal profession generally. WILLARD PARKER, M. D. Professor of Surgery, New York City Dr. S. N. Marsh's Patent Radical Cure Truss and all other kinds of Trusses, Shoulder Braces. Supporters, Elastic stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Gure Truss Offices of S.N. MARSH & CO., No. 2 Vesey St. (Astor House), ow York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. opPOSITE THE HIGH STEEPLE, Kºšº Agents for Clement's Patent Artificial Legs. | F. E. SUIRE. IF. E. Suire & Co., E. S. WAYNE wholesale dauggists, IMI AL INT TJ E" A C T TJT TER, I INT GF £Hemists AND PHAR Maceutists, CINCINNATI, OHIO. Have constantly on hand a full assortment of sye), EcºEd O'RUGS ANYO IVX)ex))(c)(N)es, ck{}eryxxcAY, APPARAºcus, TESTS, MEDICAL, GLASS WARE, &c., &c., And solicits the patronage of the trade and profession. We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate. Principles of Plants, Made in accordance with the U. S. P. and other recognized authori- ties. FINE AND RARE CHEMICALs, Of the popular class of preparations known as H. T., IDX IIHR, S, We manufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. * Bitter Wine of Iron, An excellent Chalybeate and tonic, Wine of Iron, &c. AGENTS FOR BULLOCK & CRENSHAW'S Sugar-coated Pills and Granules. Price Lists of preparations and of Sugar-coated Pills sent by Mail upon application. The long standing and well and widely known repu- tation of our house we offer as a guarantee for the reliability of our preparation, and the quality of the goods sold by us generally. º-> &= U-7Ns) |N|RTS, Carriage Manufacturer, NOS, 9 and 11 East Sixth Street, bet. Main & samº. I MAKE NOTHING BUT runsz, czar'ss work, Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of ºs- LIGHT FAMILY CARRIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive variety of light elegant designs of different cost and finish. In vehicles especially PHYSKEFANS” (SE, The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. adapted to The superiority of my light gentlemen’s buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price ; lists furnished on application. References K. to Dr. W. W. Dawson and all the leading wº Physicians in the city and heighborhood. * * * william Autenrieth, No. 71 WEST sIXTH sº IEEET, -* BETWEEN WAINUT Aſs WINE, cincinnati, ohio, MANUEACTURER • OF AND DEALER IN |||||| || || || ||||||||| Abdominal Supporters; Trusses, CLUB-F00T SHOES, - SPINAL APPARATUS, ETC Keeps constantly on hand a full variety of Metalic and Rubber syringes, Storm.ach Purmps, Etc. STOCKINGS FOR WARICOSE WEINS, Special attention given to the fitting of Apparatus for Deformities. say-Agent for Dr. L. A. BABCOCK's Silver Uterine Supporter, * - . —º- - DR AHL's Porous FELT splints, - —air- T) A. Y. * S S E L IN T S -AND- ROBERT CLARKE & Co's. IIST OF NEW MHL iBTH in Mºulis find GREEN'S PATHOLOGY AND MORBID ANATO MY, 8vo. Cloth. $2 5o DUCHENNE'S LOCALIZED ELECTRIZATION. 8vo. $3 oo DILLENBERGER ON WOMEN AND CHILDREN’S DIS- EASES. 12mo. $1 75 BENNETT ON PULMONORY CONSUMPTION. 8vo. $1 5o FIRST HELP IN ACCIDENTS. 12mo. $1 50 BEASLEY'S DRUGGIST RECEIPT BOOK. 8vo. $3 5o ECHEVERRIA ON EPILEPSY. 8vo. Cloth. $5 od HOWE ON EMERGENCIES. 8vo. $3 oo HAMMOND ON NERVOUS DISEASES. 8vo. $5 oc RINDFLEISCH'S PATHOLOGICAL HISTOLOGY. $6 oo WARINGS’ PRACTICAL THERAPEUTICS, 2nd Am. Ed. 8vo. Cloth. $5 od Leather. $6 oo SCUDDER'S SPECIFIC MEDICATION. 12mo. Cloth. TANNER'S HANDBOOK OF OBSTETRICS. I 2 mo. WAN BUREN ON DISEASES OF THE RECTUM. Cloth. $1 5o FLINT’S EXAMINATION OF URINE. Izmo. Cloth. $ 1 oo VOGEL ON DISEASES OF CHILDREN. 8vo. Cloth. $4 5o BEARD AND ROCKWELL’S MEDICAL AND SURGICAL ECECTRICITY. 8vo. Cloth. $4 5o ATTFIELD'S MEDICAL CHEMISTRY. 12mo. Cloth. $2.75 Leather. $3 25 BARTHOLOW’S HYPODERMIC MEDICATION. Cloth. $1 5o TURNBULL’S DISEASES OF THE EAR. 8vo. Cloth. $5 od TILT'S CHANGE OF LIFE. 8vo. Cloth. $5 od NEUMANN’S HAND-BOOK OF SKIN DISEASES. Cloth. $4 oo ANSTIE ON NEURALGIA. 8vo. Cloth. $3 oo. PANCOAST'S OPERATIVE SURGERY. 4to., with many plates. $1 o oo HOOD ON BONE SETTING. 12mo. $1 50 RINGER'S HAND-BOOK OF THERAPEUTICS. 8vo. $4 oo $2 5o $2 oo I 2.Ill O. I 2 IIl Oe 8vo. HOLBROOK’S PARTURITION WITHOUT PAIN. I 6mo. $1 oo PROCTER’S LIGHT SCIENCE FOR LEISURE HOURS. 12mo. $1 75 BERNARD’S PHYSIOLOGY OF THE HEART, 5octs. BARNES’ OBSTETRICAL OPERATIONS. 8vo. $4 5o NICHOL’S FIRESIDE SCIENCE. 12mo. $1 5o. WOHLER'S MINERAL ANALYSIS. 12mo. Cloth. $3 oo PLATTNER'S MANUAL OF ANALYSIS WITH THE BLOWPIPE. 8vo. Cloth. $7 50 JEFFRIES ON THE EYE. 8vo. Cloth. $1 oo MANSFIELD, A THEORY OF SALTS. 8vo. Cloth. $4 oo JEFFRIES ON THE SKIN. 8vo. Cloth. $1 oo GARDENING FOR PROFIT. 12mo. Cloth. $1 5o PRACTICAL FLORICULTURE. 12mo. Cloth. $1 5o FULLER'S SMALL FRUIT CULTURE. 12mo. Cloth. $ I WOOD WARD'S COUNTRY HOMES. 12mo. Cloth. $1 DARWIN'S ORIGIN OF SPECIES. I2mo. Cloth. $2 oo ARTHUR's TREATMENT AND PREVENTION OF DE- CAY OF THE TEETH. 12mo. $1 50° TYND ALL ON LIGHT AND ELECTRICITY. THE AMATEUR MICROSCOPIST. Small 4to. BOOKS IN PREPARATION. BRYANT'S PRACTICE OF SURGERY. BARNES ON DISEASES OF WOMEN. ROBERTS ON RENAL DISEASES. GUERSANT, SURGICAL DISEASES OF WOMEN AND CHILDREN. Medical, Scientific, and other Catologues sent on application. Any book in the above list sent by mail or express, free of charge on receipt of price- 5o 5o 12mo. $1 25 $1 75 S. W. Elliott’s Saddle-bags 65 West 4th Street, Cincinnati, Ohio. List of Pharmaceutical Preparations, MANUEFACTURE O BY Jozºv" Wºzºr & Bºozººn, FECIL.A.D.E.L.F.H.I.A. —º- ELIX PHOS. IRON, QUININE AND STRYCHNIA, - ELIXIR OF GENTIAN FERRATED, ELTXIR, WALERIANATE OF AMMONIA, - (Goddard’s Formuła,) ELIXIR VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, - Iron, with Phosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Iron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK, ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, * .-- COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER win E OF IRON, Citrate of Iron and Peruvian Bark, FERRATED CORDIAL ELIXIR, ELIXIR CALISAYA BARK, WINE AND BISMUTH, * ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, - FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, - TASTELESS COD LIVER OIL, TASTELESS COD LIVER OIL. FERRATED, BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and Sherry wine, ELIXIR WALERIANATE OF STRYCHNIA, * - . • WINE OF PEPSIN, SYRUP SUPERPHOSPHATE OF IRON. - ELIXIR OF BISMUTH, COMP. FLUIDEXT. BUCHU AND PAREIRA BRAVA. STUTE"I POSITOTE, IES. Bectum, Waginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great eare, and of every variety of combination. Lists sent on application. SPONGE TENTS.—For the Urethra, of every size and Btyle, made of finest quality of sponge. O Do R. L.E. s.s A.N D F A LATA H. L. E. In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERs & BARTLETT, of Portsmouth, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. - Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. - Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. - - In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachitic Affections, in Chronic Rheumatism, &c. - - - The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. . We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. :i Nº. s§~tº º- |s w - | | -º |;R.- ;:|t- º º--| º Cº-º-º Wilſº ". L-dº- ºssºp; & Lºlº ... .º.º. Fºº. ſ: t º Tº T Tº T- ºr =º •. º E. * A v. c *"Nh4 Rº: º ; : y : N jº ºwſ, Vºlºs tºº, NS " A. 2.º As Zs 3. # §º § f Wºry. WAN'ſº ºf * Sºlº. º * J g o p - º Sill w [* "ſº º d º T. : ſº - • *. tº a . ſ * * * *. [. º: º w “ * * ſ * * * Tº sº | - º,2S: ... ." : º * Frºm -- J M ſ es t WIZS º t º '' º: Eºs . - 7S & III: . ". . .* tº | | HIM|... '" m In ſ ſ º a | Sº º { | l ! sº J i rt ; : ! - tº - º-º-º-º: ſ º ſ ſ || 1 || - - - - - | #. | d º t - ||||||||II . . - º # , || º s' || * : ! a ºr- * - ſ isi-...-ſtill - - t -- - - - ---- --- §§§ *: | : *.: º, ſº º ſ P º &A t R. \ º º -|F. - ‘.|º|; º| - || CINCINN ATI. —-º- IF. A. C. TCſ IL T Y. J A M E S G. F. A. H. A. M., M. D., D E A N, Professor of the Theory and EPractice of Medicine and Clinical Medicine. ROBERTS BARTHOLOW, M.D., Professor of Materia Medica and Therapeutics. W. H. GOBRECHT, M.D., Professor of Anatomy. P.'s, CONNER, M.D., Professor of Surgical Anatomy. JAMES T. WHITTAKER, M.D., I’rofessor of Physiology. SAMſ JEL NICKLES, M.D., Professor of Physics and Medical Chemistry W. W. DAWSON, M.D., Professor of Principles and Practice of Surgery and Clinical Surgery C. D. PALMER, M.D., Professor of Medical and Surgical Diseases of Women. T. A. REAMY, M.D., - Professor of Obstetrics and Diseases of Children. JOHN L. CLEVELAND, M.D., Demonstrator of Anatomy. CHARLES KEARNS, M.D., Assistant to the Chair of Surgery W. W. S.H.E.L.Y., M. D., Professor of ID is eases of the IEye and HXar, and Secretary of the Faculty- **- T. LOUIS BRow N, M. D., Prosecutor of Anatomy. *_º E. Noble, Janitor, College Building, Sixth St., bet. Vine and Race Priuted and Published by Noan Is & M Unny, Medical College of Ohio Building, Cincinnati. LINIC. IPTUELISPHIED EVERY SATURDAY. TERMS-$2.00 a Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editor: All Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer. C IN C IN N ATI, A P R IL 20, 1872. —º No. 16. Vol. 2. JAS. T. whitTAKER, M. D. - - - Editor. No. 101 West Ninth Street, Cincinnati. -A-SSOCIALTIEH FRIDITOR,S. W. W. D.Awson, M. D. THAD. A. REAMy, M. D. P. S. ConnºR, M. D. C. D. PALMER, M. D. W. W. SEELY, M. D. SAMUEL NICKLEs, M. D. CHAs. KEARNs, M. D. JNo. L. CLEvKLAND, M. D. RoBERTs BARTHollow, M. D. 3. W. W. SEELY, M. D., gº º ºs º º º No. 118 West Seventh Street, Cincinnati. CLU B R AT Es, *=e TREASURER." 4 Copies to one address...................................................... $ 7.00 6 é & & 4 - 10,00 12 & £ & & ~ * 18,00 C O N T E W T S. º Tºmº Page ORIGINAL ARTICLES Chronic Catarrh of the Middle Ear by W. W. Seely, M.D................ Surgical Notes by P. S. Conner, M. D. - - 183 TRANSILATION The Diagnosis of the First Stage of Carcinoma Colli Uteri (From the Archiv. f. Gynaekologie vol. iii Sect. 2. 1872.)........................ 185 ACAIDEMIY OF MIE DICINE Transactions April 13, '72. Dr. Kearney on Syphilis—Dr. Carson on Anti-pyretic Action of Qui- - nia 187 MIE DICAI, NEWS. American Medical Association—The Emperor of Brazil—The Med- licott Case—Bound in Human Skin—Bellevue Hosp. Med. Col- lege—N. Y. Univ. Med. College—Blockley Hospital; Phil. Closure of the Paris School—Lostorfer's Syphilis Discovery..188-189 CO RRESPONDENCE Letter fron Dr. Wright—Jackson's Cough Syrup CLINICAL, MIENIORANIDA Menstruation from the Mammae—Removal of Foreign Bodies from 189 the Ear by Agglutination—Uterine Intermittent Polypus—Cold Applications in Hyperperexia—Morphia and Chloroform Com- bined 190-192 The early recognition of carcinoma uteri, of highest importance in therapy, is made easy by the points estab- lished in our translation of to-day. Wedl was on time as will be seen by the date of his letter but he was not quick enough to prevent the dis- semination of Lostorfer's views all over the civilized globe. •. The discussion on hyperperexia contains the points on this subject which is now exciting so much interest. Morphia and Chloroform combined is a valuable |J. TAFT, co-Arr se ces |Fashionable Hatters, IMPORTERS AND MANUFACTURERS OF Hºs’ FºxS, loo wrisT FOURTH ST. Opposite Post Office, cINCINNATI. sarspecial Inducements to Medical Men- *ENGRAVERSonwooD. SCINCINNATIOHIO: - Bº * Still Y º Editor Dental Register J. & W. TAFT, TXIEHINTTISTS 117 WEST FOURTH STREET, CINCININATI, O. A Monthly Journal, CONTAINING 48 PAGES, *tion to materia medica, again from, scientific Devoted to the Interests of the Dental Profession, experimentation, List of Pharmaceutical Preparations, Jonºv wrºnºmnorarn, FRILADELPHIA. —ºn- ELIX PHOS. IRON, QUININE AND STRYCHNIA, ELIXIR OF GENTIAN FERRATED, ELIXIR WALERIANATE OF AMMONIA, - (Goddard’s Formula,) - fixiºvaLERIANATEAMMORIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, Iron, with Phosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Hron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK, - ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, - COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER WINE OF IRON, citrate of Iron and Peruvian Bark, FERRATED CORDIAL ELIXIR, ELIXIR CALISAYA BARK, WINE AND BISMUTH, r ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, - TASTELESS COD LIVER OIL, TASTELESS COD LIVER OIL. FERRATED, BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and Sherry wine, ELIXIR WALERIANATE OF STRYCHNIA, WINE OF PEPSIN SYRUP SUPERPHOSPHATE OF IRON, *- y ELIXIR OF BISMUTH COMP. FLUIDEXT, BUCHU AND PAREIRA BRAVA. * sur-FO's ITORIEs. Rectum, Waginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great eare, and of every variety of combination. Lists sent on application. SPONGE TENTS.—For the Urethra, of every size and style, made of finest quality of sponge. William Autenrieth, ROBERT CLARKE & G0’S. LIST OF NEW MHL iBTH in Mºllis Hilº, GREEN'S PATHOLOGY AND MORBID ANATO MY, 8vo. Cloth. $2 5o DUCHENNE'S LOCALIZED ELECTRIZATION. 8vo. $3 oo DILLENBERGER ON WOMEN AND CHILDREN’S DIS- BKTWERN WAINUT AWA WINK, EASES. 12mo. $1 75 BENNETT ON PULMONORY CONSUMPTION. 8vo. $1 5o FIRST HELP IN ACCIDENTS. 12mo. $1 5o BEASLEY'S DRUGGIST RECEIPT BOOK. 8vo. $3 5o ECHEVERRIA ON EPILEPSY. 8vo. Cloth. $5 od CINCINNATI, OHIO, HOWE ON EMERGENCIES. 8vo. $3 oo HAMMOND ON NERVOUS DISEASES. 8vo. $5 od RINDFLEISCH’S PATHOLOGICAL HISTOLOGY. $6 oo MANUFACTURER OF AND DEALER IN WARINGS’ PRACTICAL THERAPEUTICS, 2nd Am. Ed. ,- 8vo. Cloth. $5 oc Leather. $6 oo SCUDDER'S SPECIFIC MEDICATION. 12mo. Cloth. $2 50 * | TANNER'S HANDBOOK OF OBSTETRICS. I 2 mo. $2 oo |||}|| || || ||||||||||}|ºś 3;ºcº ſº. Cloth. $1 5o FLINT’S EXAMINATION OF URINE. 12mo. Cloth. $1 oo tº VOGEL ON DISEASES OF CHILDREN. 8vo. Cloth. $4 50 Abdominal Supporters, Trusses, BEARD AND ROCKWELL’S MEDICAL AND SURGICAL ECECTRICITY. 8vo. Cloth. $4 50 ATTFIELD'S MEDICAL CHEMISTRY. 12mo. Cloth. $2.75 Leather. $3 25 BARTHOLOW’S HYPODERMIC MEDICATION. I.2mo. GLUB-FOOT SHOES, t- Cloth. $1 5o TURNBULL's DISEASES OF THE EAR. 8vo. Cloth. $5 oc TILT'S CHANGE OF LIFE. 8vo. Cloth. $5 co SPINAL APPARATUS, ETſ NEUMANN'S HAND-BOOK OF SKIN DISEASES. 8vo. Cloth. . $4 oo ANSTIE ON NEURALGIA. 8vo. Cloth. $3 oo. PANCOAST'S OPERATIVE SURGERY. 4to., with many plates. $10 oo HOOD ON BONE SETTING. 12mo. $1 50 RINGER'S HAND-BOOK OF THERAPEUTICS. 8vo. $4 oo Metalic and Eubber syringes, HOLBROOK’S PARTURITION WITHOUT PAIN. I 6mo. $1 oo Stormzach Pumps, Etc., PROCTER'S LIGHT SCIENCE FOR LEISURE HOURS. 12mo. $1 75 BERNARD's PHYSIOLOGY OF THE HEART. 5o cts. BARNES’ OBSTETRICAL OPERATIONS. 8vo. STOCKINGS FOH WABGOSE WEDNS, NICHOL’S FIRESIDE SCIENCE. 12mo. $1 5o. $4 5o No. 71 WEST SIXTH sº IEEET, Reeps constantly on hand a full variety of 3 WOHLER'S MINERAL ANALYSIS. 12mo. Cloth. $3 oo & & º & ... |PLATTNER'S MANUAL OF ANALYSIS WITH THE Special attention given to the fitting of Apparatus for Deformities. BLOWPIPE. 8vo. Cloth. $7 5o JEFFRIES ON THE EYE. 8vo. Cloth. $1 oo MANSFIELD, A THEORY OF SALTS. 8vo. Cloth. $4 oo B& Agent for DR. L. A. BABCOCK'S JEFFRIES ON THE SKIN. 8vo. Cloth. $1 oo s GARDENING FOR PROFIT. 12mo. Cloth. $1 5o PRACTICAL FLORICULTURE. 12mo. Cloth. $1 5o Gy * FULLER'S SMALL FRUIT CULTURE. Izmo. Cloth. $ I go Silver Ujëerine Supporter, WOODWARD'S COUNTRY HOMES. 12mo. Cloth. $1 : DARWIN'S ORIGIN OF SPECIES. 12mo. Cloth. $2 oo ARTHUR'S TREATMENT AND PREVENTION OF DE- -ALSO- CAY OF THE TEETH. 12mo. $1 50 TYNDALL ON LIGHT AND ELECTRICITY. Izmo. $1 25 DR. AHL'S POROUS FELT SPLINTS, THE AMATEUR MICROSCOPIST. Small 4to. $1 75 BOOKS IN PREPARATION. -ALSO– BRYANT'S PRACTICE OF SURGERY. BARNES ON DISEASES OF WOMEN. ROBERTS ON RENAL DISEASES. D A. Y. * S S E LIN T S Güer's ANT, surgical Diseases of women AND CHILDREN. Medical, Scientific, and other Catologues sent on application. Any book in the above list sent by mail or express, free of charge on receipt of price- * S. W. Elliott's Saddle-bags 65 West 4th Street, Cincinnati, Ohio. -AND- --> *-*. --- -- - --- Marvin's - - -- - COTD TLTTV FIF, GDIT_ O' D C E L E S s A.N ID PA. L. A.T.A. B. L. E. In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERs & BARTLETT, of Portsmouth, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachitic Affections, in Chronic Rheumatism, &c. The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufact ture of the Oil, have retired altogether from its sale, which is in our hands only. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. HMHiſ MF; tıWºr 167 EAST 34TH-ST., NEW YORK, By Special Appointment Electrical Instrument Makers to the New York State Hospital for Nervous Diseases, MANUFACTURERS OF PoETABLE ELECTRO-MAGNETIC MACHINES, Portable Galwanic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, 1870, and May 30th, 1871. These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery Fluid. - |M|| ||||||—|| ||||||} PEERMANIENT BATTERIEs, For Hospitals and General Practitioners, IET IIECTIER, OTDIEHS. For Eye, Ear, Larynx, Nose, Uterus, Vagina, Bladder, Ree- tum, Feet, Phrenic and Sympathetic Nerves, Eleo- trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. EXTRA (!TS FROM THE OPINIONS OF THE MOST JEIMINTENT IMEIMB EES OF THIS PROFESSION. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “Nothing CAN ExCEED THE EFFICIENCY AND convKNIENCE of THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” We are authorized by Prof. Hammond to announce em- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- proved and re-modified Instruments made by our Company. MEREDITH CLYMER, M. D., Prof. of Diseases of the Neº- vous System and of the Mind, &c., &c.—“I consider the ºr Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prof. of Surgery, St. Louis:– “In neat- neSS, compactness and efficacy, they can not be excelled.” ALFRED C. GARRATT, M. D., Boston :-"In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” Similar Testimonials have been received from JOHN J. CRANE, M. D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A, MURRAY, M. D.; QHAS. E. BLUMENTHAL, M. D.; E. C. SEGUIN, M. D.; ALLEN MAYNARD, M.D., Cleveland, O.; Dr. C. WANNIE, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES KELLY, Florence, O.; Dr. JOHN BECKER, Brighton, Iowa; Dr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes. barre, Pa.; JOHN J. CALDWELL, M. D., Brooklyn, and mºny ºther prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, bºth theoretically and practically, what is required in an Electrical Instrument for medical purposes. CALL OR SEND FOR CIRCULAR AND PRICE LIST. FošTER’s IF_A_TIERINTT WA) Are furnished to Officers and Soldiers on Government account. I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMES A. EOSTEER, 9II Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cincinnati, Ohio, or 172 Jef- ferson Avenue, Detroit, Mich. SAML. P. THOMAS T.A.. I I, OR, DEALER IN %23 **...tº º º: * º, e. ** 22. *_- º -\w. \\º WA: * - V' ºwn - \, \, \ W.A.W. § W. W English, French and Scotch GOOIDs, 34 West Fourth Street, & M.W.C.A.W.W.?? /. F. E. Surke. E. S. WAYNE mü. JR, & Co. --- |TER, Instrument Makers and Practical Opticians, Beg leave to return thanks for the patronage extended to them through || a long series of years (having been established since 1836), and in the reorganization of their firm will endeavor to merit a continuation of the same. We wish it understood by the Profession and the Public generally that our invariable rule is, to make or import none but the best in- struments. Those in want of any of the acknowledged good aids of vision to imperfect eyes, will always find the best and largest stock of Leruses, Spectacles, and the best models procurable, with pains- || taking 8 kill to adjust them to all conditions of sight, at our house. Special attention paid to orders for Fine Microscopic Objects and ** Apparatus, Magnifiers and Readers in great variety. edical Batteries, Barometers, Thermo- meters, Hygrometers, Urinometers and Rain Gauges, of the most approved constraction always on hand. All orders promptly and accurately filled. - - - - . JAS. FOSTER, JR. F. S. SHACKLEFORD, } S. W. Cor. Fifth & Race Sts., Cincinnati, 0. S &º No. 758 BROADWAY, New Yons HAVE been in the habit of applying and recommending the Truss manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- I ** JAs. Foster, J.R. & co. | F • E. Suire & Co., wholesale Daugatsts, |M. A. N. UE A cru IRIN G £HEMists AND PHARMAceutists, CINCINNATI, Ohio. Have constantly on hand a full assortment of sex ecºeo xºgos ANo moeoxexses, cºewear areawards, TESTS, MEDICAL GLAss wARE, &c, &c., And solicits the patronage of the trade and profession. we would call attention to our select preparations, such §§ Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, Made in accordance with the U. S. P. and other recognized authori- ties. EINE AND EARH, CHEMICALS, of the popular class of preparations known as - IF. T., ILXII IF, S, We manufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. - Bitter Wine of Iron, An excellent Chalybeate and tonic, Wine of Iron, &c AGENTS FOR BULLock & CRENSHAw's Sugar-coated Pills and Granules. Price Lists of preparations and of Sugar-coated Pills sent by Mail upon application. The long standing and well and wideb known repu- clusion of all others, and have found it to give general Satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined. LEWIS" A. SAYRE, M. D. Surgeon, Bellevue Hospital. From Prof. Willard Parker to S. D. Townsend, M. D., Surgeon to the Massachusetts General Hospital. BEG leave to state for the benefit of all concerned, that I have known Dr. S. N. Marsh the last fifteen years. I am in the constant habit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have ever Seen, and his treatment is unattended with any of the risks to the patient that exist in many of the plans suggested and attempted to be carried. into execution. I have confidence in Dr. Marsh as a gentleman of honor and integrity, and as such recommend him to the members of the medi- cal profession generally. WILLARD PARKER, M. D. Professor of Surgery, New York City Dr. S. N. Marsh's Patent Radical Cure Truss and all other kinds of Trusses, Shoulder Braces, Supporters, Elastic Stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Cure Trugs Offices of S. N. MARSH & CO., No. 2 Vesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. OPPOSITE THE HIGH STEEPLE, Jº Agonts for Clement's Patent Artificial Legg. tation of our house we offer as a guarantee for the reliability of our preparation, and the quality of the goods sold by us generally. T EL EL C. T., T N T C. 181 wº- Vol. 2..] S A T U R D A Y, A P R I L 20, 1872. [No. 16. O R. I. G. I. N A L A R T I C L E S. *- —º-e-Cº- CHRONIC CATALRR. H I OF THE MII DI DI LE EAR. BY PROFESSOR: , SEELY. A Clinical Lecture delivered at the Dispensary of the Medical College of Ohio. GENTLEMEN: Unquestionably the form of ear trouble represented in the cases before us is the one aural surgeons meet most frequently. It is the greatest source of deafness. I have had a field so rich in typical cases that you have already become somewhat familiar with the various forms of ear trouble, and your personal exami- nations will be invaluable to you. I have shown you the form of trouble in question, in children, the middle aged and the old. º So you will infer at once that it is a disease not con- fined to any age. Some of you perhaps will recall my remarks made from time to time on the acute or sub-acute catarrh of children, when we had a redness of the membrana tympani, with haziness and concavity, and ear-ache. In speaking of the significance of ear-ache in children, I called especial attention to the necessity of always "making a speculum eacamination in order not only to assure 3/0urselves that ear-ache in children is not “nervous,” as a cule, but inflammatory, that the proper remedies may be ºresorted to for destroying the seeds that are being sown for the chronic trouble that I have presented yaw in older chil- dren, some of whom had suffered from ear-ache as children. We may have then the chronic form of inflammation of the middle ear resulting from the acute or sub-acute. It is not a little instructive to see how many persons With impairment of hearing have as children suffered with ear-ache. You may be surprised, gentlemen, when I tell you that it is not an easy matter to find perfect membranae tympanorum for illustration, that probably not more than one-half between the ages of 20 and 40 have per- fect hearing, and that after 50 or 60 the percentage is reduced almost to 0. Undoubtedly this percentage will be Very much altered by the spreading of the advances in aural science. It was not till quite lately that an aurist could see a case of “ear-ache” in a child. As a rule those cases have passed over into the chronic stage and increasing deafness is the alarming symptom. The mother is surprised that the child has not “out- grown it.” I trust, gentlemen, none of you will present the uncouth spectacle of “ignoring a serious trouble,” when science points out such a sure way of overcoming it. I am frequently asked if I believe in an “hereditary deafness,” and if any thing can be done. Undoubtedly there is an hereditary tendency to inflammation of the mucous membrane of the middle ear—for that is the trouble—and just as undoubtedly can that inflammation be combatted. We combat successfully bad inheritances in other parts of the system. Why not in the ear? The con- dition of ear patients is no longer a standing reproach to the science of medicine, for at the present day aural science is on a level with the other departments of medicine and surgery. The great difficulty yet in the way of a more popular recognition of this department, is the fear that damage may be done, a fear made popular by the profession, and only really to be perfectly overcome by the influ- ence of the profession. Another difficulty, is the length of time required to, even, in many cases, produce any improvement. Many times these cases of chronic catarrh of the middle ear require long months even before any signs of improvement appear. Some of your most satisfactory results will be had in cases that require treatment more or less continuous for one or two years. You can see that nowhere will your patience and powers of per- severance be more severely taxed than in such cases. In fact, gentlemen, let me tell you that there is no quality a physician should be so wanting in as impa- tience, with it many a man has lost some of his rarest opportunities for success. How is chronic otitis media recognized? The membrana tympani forming as it does the boundary between the middle and external ear with its inner surface lined with mucous membrane, continuous with that of the middle ear, would certainly commend itself as the first part upon which we are to seek our knowledge of the cavity of the drum. We find the changes in this membrane affecting direction, color and the light spot. All are usually found, but are not necessarily pathognomonic of chronic catarrh. As our time is limited I will simply call your atten- tion to some of the appearances more usually presented, remarking simply in passing, that what the membrane reveals in regard to a prognosis is as yet exceedingly uncertain, as also the exact location and extent of the trouble. Frequently the color of the membrane varies little from normal, though the epidermic and the cuticular layer may be so affected that the membrane is dull, hazy, the triangular light spot being not only altered in shape, but even entirely absent. Such facts in the absence of all external trouble would readily lead us to infer trouble in the cavum tympani. 182 [APR. 20, 1872. TIEEE THE CIT, I. TST I. C. You will be liable to err in your diagnosis, if you ex- pect to find redness as a symptom of inflammation, for only when you have more or less acute or sub-acute forms do you find any redness or congestion of the vessels along the handle of the malleus. It is always difficult to persuade patients that any- thing like inflammation has been going on in the ear, for they think that pain should be present. In this chronic form, the handle of the malleus is frequently, (usually) very prominent, and the short process, in particular, presents as a prominent white' point. The membrane is concave sometimes regularly on both sides of the malleus, sometimes irregularly, owing to various kinds and positions of the adhesive pro- CeSSéS. As the changes in the middle ear go on, these changes in the color and position of the membrane alter. I have presented you a case where the membrana tympani was much thicker than normal so that the attachment of the malleus could not be discovered. Again a case of almost pearly whiteness of the membrane. Not un- frequently we find calcareous deposits in the membrane. Bear in mind that these spots are not evidences of long continued trouble, for they are found in the mem- branes of children. Again, you will find too, that they are not incompatible with good hearing power. I have already remarked that the examination of the membrane alone is not sufficient to tell you either of the hearing power, or of the possibilities of the effects of treatment. Many times, even when the changes in the membrane are few and slight, the hearing is not only bad, but the possibilities for improvement are few. I shall have an opportunity of referring to a special form of trouble in the ear to illustrate this allusion more forcibly. Our second means of diagnosis is catheteri- sation of the Eustachian tube. This brings me to the still further explanation of the position of the membrana tympani. I have spoken of the formation of adhesive bands. In cases of what is called catarrh of the Eustachian tube, we have the membrane abnormally concave, very slightly changed in color. So that we are able now and then to see the parts of the middle ear, e.g., the pro- montory, the vertical process of the incus, etc., ; a very marked case of which occurred in my wards in the Cincinnati hospital some time ago. The concavity in these cases, as well as in catarrh of the middle ear, occurs probably as a consequence of the atmospheric pressure from without. You are aware that the middle ear normally is filled with air, kept in equilibrium with the outer air by means of the Eusta- chian tubes. Now if these tubes become closed, the air in the middle ear becomes absorbed by the circulation and the metamorphic processes, and the pressure from without drives the membrane in against the promon- tory. By means of the Eustachian catheter we are enabled to inform ourselves still more of, not only the condition of the tubes, but of the state of the middle ear. We are informed of the more or less permeability of the tube, of the elasticity of the membrane, as to whether it is more or less fixed by adhesions, of the moistness or dry- ness of the mucous lining of the tympanic cavity. While both of these diagnostic means should always be resorted to, can we rely implicitly on this evidence, that we are in the presence of chronic catarrhº. At some future time I will endeavor to show you a little more in extenso that we cannot. There are then other points that come in either to modify or rather to assist in our diagnosis. One of the favorable points usually mentioned in catheterization is, that the patient after the process hears better and the noises are less. This cannot be relied upon always. I have spoken of the so-called “dry catarrh” in which this process while it may produce some immediate improvement may be followed by a rapid diminution in the hearing. A large majority of patients with middle ear trouble, combined or not with tubal trouble, will tell you that changes in the weather affect their hearing. The more marked and sudden the changes, the more the Eustachian tube is involved. The mucous membrane of the tube is more exposed to the air consequently more rapidly thickens, absorbs water, which along with the usual increased secretion of such a membrane, rapidly blocks up the tube. We find cases where the sounds on catheterization are good and yet the hearing power is very much reduced. Probably I need scarcely call your attention to the fact, that the parts that convey the sound to and through the middle ear are of far less consequence than those that transfer it to the inner ear, to the nerve. You will also readily understand that a catarrhal pro- cess, while the general law is, that mucous membranes continue a morbid process by continuity of surface, may be confined to localities, and such localities have been demonstrated in the ear to be the two fenestrae, those membranes that cover the openings leading into the internal ear. To resume, if the variations in the hearing are sudden and marked, we infer that the tubes are the chief seat of the difficulty; if the changes are not so rapid and great, we infer trouble in the middle ear; if the diminu- tion in the hearing power is great, the strong probability is that the cause lies in an affection of the membranes covering the fenestrae. The exact value of the mastoid processes as accessory structures is not accurately determined. Of course, in- creasing the quantity of air to be set into vibration, they act somewhat as a resonator, and knowing the tendency of mucuous membranes to propagate an inflammatory process per continuitatem, we must suppose in all long continued troubles of the middle ear, more or less affec- tion of the mastoid cells. APR. 20, 1872.] TIEEE EIH C T III INTI C. 183 Prognosis. Certain points admitted, the prognosis is very favor- able. Time and perseverance given, treatment will, if inot cure, at least decidedly improve a large majority of the cases. º Many times it is impossible to give an opinion until the case has been seen even four or five weeks. Espec- ially in patients that come from a distance subjected to the changes of leaving home. Do not be discouraged, if after weeks of trial you.have brought about little or no improvement. You will see by this that the treat- ment is to be regarded as part of the examination, the test by treatment, for I have already remarked that we are unable to tell exactly where the trouble lies, and exactly what its nature is. Then do not be too hasty in forming your conclusions. Treatment. The treatment is as a rule both constitutional and local. If the patient complains of taking cold very easily, perhaps almost every day, there is nothing prob- ably that will so effectually prevent it as the iodide of iron, continued for months. You could scarcely expect much permanency in the improvement so long as the constitutional tendency to taking cold continued. Locally, the air douche to the middle ear, medicated or pure, and remedies to the throat if there seems to be a good deal of irritation. I am always in the habit of beginning the treatment of my cases with the air douche to see what the effect will be of so simple a remedy. If there is a considerable Secretion I inject some astringent solution through the catheter into the ear. Making use generally of a weak solution of zinc, (3–3 grs. ad 3i aq). If I wish to cause irritation or absorption I use muriate of ammonia, (2-5 grs. ad. 3i aq). If the tubes are so closed that but little air enters, I dilate mechanically, as we dilate strictures of the nasal duct, making use of an ordinary fiddle string, about letter E. Do not be too ambitious to inject vapors or fluids into the ear, for very frequently the simple mechanical effect of the air douche will be sufficient. Unquestionably, if we could know our case, the ex- citement of an intense acute inflammation in the middle ear and the proper treatment of it, would accomplish an immense amount of good, a plan of treatment that corres- ponds with “inoculation,” of the conjunctiva for Pannus, or what it means, to the excitement of an intense conjunctival inflammation to carry off the neo- plastic matter. I feel confident that such a plan of treatment for some of the old obstinate middle ear troubles would be attended with less risk than the excite- ment of a violent blemorrhagia to the eye. Every one probably has seen the marked results of idiopathic sub- *ºute attacksin otitis media chronica. This air douche should be made use of every day, provided no irritation of the throat is caused by the “catheter. If ice or *mmonia is used, a sitting of once a week will frequently be sufficient. If stimulating remedies "are used, it is well to allow -the ears periods of rest. Treating them regularly for a few weeks then desisting for a few weeks. In closing my remarks I must caution you against not only not giving your patient pain, but also not pro- ducing irritation of the throat by the catheter. Cather- terization is a comparatively simple operation, and yet I am continually seeing patients in whom the only bar to improvement was the awkward manipulation of the operation. The catheter is introduced, but the irritation produced prevents any favorable result. —-º-º-º- S U R G I C A L N 0 T E S . BY P. S. Con NER, M. D. Prof. Surgical Anatomy Medical College of Ohio. Lyell’s “Displacement of the Radius.” Case 1. F. N., aet. 2 years. Some hours before hurt by nurse swinging her by the hands; afterwards very fretful, complaining of pain when left arm was touched. When seen the left forearm was partially flexed on arm, the hand about three-fourths fully pronated, the motions of shoulder elbow and wrist unimpaired and painless, the slightest attempt at Supination caused pain, (though gentle motion showed that the head of the radius moved with the shaft), no tenderness on pressure upon any part of the forearm and hand except over the upper sixth of radius. Not being able to determine the nature of the injury, but from the tenderness suspecting incomplete fracture somewhere in the upper fourth of the radius, I put the forearm in a state of complete supination and secured it by adhesive straps to a dorsal splint. The child very quickly became quiet and was sent to her home a short distance in the country. On the fourth day afterwards (as I learned from the physician in charge), upon tak- ing off the splint it was found that the difficulty what- ever it had been had entirely disappeared, all motions of forearm and hand being painless and complete. Further treatment was consequently discontinued. A few days afterwards Isaw a paper by Dr. Lyell, originally published in the Glasgow Quarterly Journal, calling atten- tion to a “curious displacement of the radius,” previously undescribed by surgical writers, so far as known occur- ing only in children under five years of age, generally in girls, apt to be frequently reproduced. The described symptoms of this displacement agreed So well with those observed in the case above mentioned, that I was satisfied of the nature of the latter. Fortunately for my patient I had adopted the very treatment recommended by Lyell, viz., forced supination, though the application of the splint was an unnecessary annoyance to the child. Case 2. S. B., ast, 23 years, hurt her right arm 184 [APR. 20, 1872. TIEI H. C. T., T N T C. in some way unknown. Symptoms identical with those of Case 1, given. Recognising now the na- ture of the accident I supinated the forearm, making at the same time slight pressure over the head of the radius. All pain and deformity were at once relieved, the child began laughing and playing around the room. Up to the present writing there has been no recurrence of the displacement. A j “Lyell’s displacement,” (as I thinkinjustice to the descri- ber the injury should be denominated), is not to my knowledge referred to in any surgical work. I have never seen but the two cases mentioned, yet these cases were met with within three weeks of each other. The relief is easy and immediate when the character of the injury is recognised. Of the exact nature of the injury I have been unable to satisfy myself. Very probably Lyell is correct in his belief that “the radius somehow catches on the adjacent ulna and is there retained,” whether or not from over- supination, as he thinks, is perhaps questionable. Backward Dislocation of the Wrist. F. S., aet. 22 years, brakeman. Dec. 12, 1871, fell or was thrown from a freight car, the brake of which he grasped with his right hand in an attempt to save him- self. When picked up was found to have received some injury about the right wrist. Through the kindness of my friend Dr. J. L. Cleveland, I saw the patient soon after he was hurt. There was a very well marked prominence on the dorsum of the forearm just above the normal line of the wrist, the upper margin of which was smoother and more rounded than in any case of Colles fracture I had ever seen. Upon making extension the deformity was relieved and showed no disposition to reproduce itself. Immediately afterwards it was found that lateral motion of the wrist upon the forearm could be readily made to the extent of at least one-fourth to one-third inch to either side. No crepitus at any point could be elicited either before or after reduction was made. Palmar and dorsal splints were applied and the wrist kept at rest. In a private note to me Dr. Cleveland writes, “The dressing was re- moved four weeks after the accident at which time it was found that mobility existed in wrist-joint though it was restricted and painful on account of the long fixed position. There was no deformity except slight swelling. Passive motion was ordered and a hydrant douche twice or thrice daily. It was thought advisable to still support the wrist by a roller bandage. Two weeks afterwards (six weeks after the accident), motion had much im- proved and the patient felt so well that he commenced light work on the road (flagging), though he could not use his right hand. The last time I saw him, Feb. 10th, he was continuing to improve and the only deformity apparent was slight thickening of the wrist. But he could not grasp anything with his right hand. Yester- day (April 5,) heard that he was beginning to use his hand somewhat.” The case was, I am certain, one of backward dislocation of the carpal-bones accompanied with extensive laceration of the ligāments of the wrist- joint. Every one knows how very rare such dislocations are, and I feel under many obligations to my friend Dr. Cleveland for giving me the opportunity of seeing and making the first examination of this case, the only one of the kind I have met with. Undescended . Testes. E., aet, 35, married 10 years, no children. A tall robust heavily-bearded man, hair upon and above pubes abünd- ant, penis normally developed, scrotum exceedingly Small scarcely more than a slight fold of skin, testicles absent, one to be felt behind right internal abdominal ring, the other perhaps, just external to and slightly above left internal ring. Venereal desirès stated to be very strong, erections vigorous, emissions complete and abundant, not followed by any sense of exhaustion. The microscopical évaminations that I made of the ejacu- lated fluid did not reveal a single spermatozoid. Cases of monorchidism (non-descent of one testicle) are not so very uncommon, but those of cryptorchidism, where both testes are retained, are very much rarer. The case mentioned above is the third that I have met with, the other two being discovered. in examining about 5,000 'recruits. Amomg 10,800 recruits for the British army, Marshall found but a single case. Very possibly many may exist of which nothing is known, for every care is generally taken to conceal such a deformity, and as it is irremediable, only accident or the determining of the question of fruitfulness will bring about a discovery of its existence. To the cryptorchid and to medical men the question of the functional value of retained testes is a very intereting one. John Hunter wrote, “when one or both testicles remain through life in the belly I believe that they are exceedingly imperfect; ” and in this, as in many other respects, his views were as correct as they were in advance of those of his own and immediately succeeding years. However much we may at first be inclined to believe with Owen that “there is nothing in such a situation which necessarily tends to impair their efficiency, (i.e., that of the retained testes), and that their continuance in the abdomen º * may influence the quantity but not necessarily the quality of the secretion;” yet when we ask what has been the result of microscopical exam- inations, the universal answer is no spermatozoids present. The presence or absence of these is the sole thing to be determined. Virility even to an unusual degree may be present and yet the fructifying elements be wanting in the seminal discharge. Curling declares that “spermatozoids have not been discovered after death in the spermatic ways of a detained testicle in any one instance that I know of.” It will not do to accept such a report of post-mortem examinations as that given by Sir Astley Cooper, “testicles of nearly the normal size and seminal tubes full of semen;” as is .APR. 20, 1872.] T H. H. C.L.I INTI C. 185 well known there may be apparently an abundance of to-the-eye-healthy semen with entire absence of the fructifying elements. In the seminal discharges of living cryptorchids no microscopist so far as I can find has ever discovered spermatozoids. To such evidence of necessary infertility presented among others by Godard, Goubaux, Follin, Liegois and Curling, it is neither scientific nor just to oppose a statement like Casper's that “experience proves that cryptorchids are per- fectly capable of procreation,” even though supported by such cases as have been reported by Reigel, Valette, Poland, Coulsen, Curling and others, in which cryptor- chids have married and had children. The maxim “Pater est quem nuptia, demonstrant,” however good in Law will not alwayshold good in fact. How can alleged paternity of six children be reconciled with post-mortem evidence that the retained testicles were apparently un- developed (not "atrophied), and no spermatozoids were discoverable, as was the case in Curling's patient. Most generally neither the volume nor consistence of retained testes have been found to equal those of normally placed organs. Very commonly they have undergone fatty degeneration especially affecting the tubuli seminiferi. That occasionally a cryptorchid may be found whose testicles are in all respects healthy is possible perhaps, but thus far, a case is not to my knowledge on record. —-º-º-º- THE DIAGNosis of THE FIRST stage of CARGINoMA colºr UTERI. With Observations on its Pathology and Therapy. BY PROF. OTTo SPIEGELBERG, (Breslau). º From the Archiv. fir Gynalkologie vol. iii, sect. 2, Berlin, 1872. The recognition of the first local beginning of cancer of the uterine cervix is attended, as is well known, with difficulties; indeed, so far as an absolute certainty is concerned, it has been considered—except in those cases where the disease has opened out with exuberations— impossible, more especially when it occurs as circum- scribed (papular) or more diffuse infiltration, with the mucous membrane intact. “Diagnostic difficulties in all the forms of uterine cancer are only encountered in those cases in which the mucous membranes remains intact, otherwise expressed, in that stage of the so-called carcinoma in which there is as yet no destruction of tissue. Here, however, the difficulties are so great that it is only in the rarest cases that a positive diagnosis may be established. It is still relatively simple and easy if one or more hard, nodulated masses may be felt beneath the smooth mucous mem- brane of the cervix but it is out of our power to differ- entiate those cases characterised by an enlarged, smooth, hard and markedly swollen cervix from simple benign hypertrophy or from chronic metritis. Seductively thorough as the rules for differential diagnosis given in the various text books seem to be, in practice, with re- liance gnly on the sense of touch, the so-called tactus eruditus, diagnosis is always dubious and uncertain. It would be of the highest importance in therapy if we could early recognise those cases in which a portion of the cervix is still apparently sound.” With this portrayal, Gusserow in his else so excellent essay on “Carcinoma Uteri” (p. 22) characterises our knowledge, and it is this and more especially the state- ment at the close which prompts me thus early to a communication which I had reserved for a more pretentious article. From an extensive field of observation and from con- siderable reflection as to its pathology I believe myself justified in giving the following as perfectly certain evidences of cancerous infiltration, viz., a peculiar indu- ration of the cervix, the disposition of its mucous membrane and its reaction to dilatation under Sponge tents. Ever since I have learned these signs they have never left me in doubt as to the differentiation between carcinoma, with the mucous membrane entire, and simple diffuse or circumscribed hyperplasia, the so-called benign in- duration, though the decision, it is true, in considera- tion of the rarity of carcinoma, was almost always in favor of the simple induration. The hardness of the cancerous deposit in comparison with the consistency of a simple induration, be it never so dense and cicatrical like, is well known ; still the judgment in such a case is altogether subjective, and the bounds between the two diseases are always hard to determine. I will therefore not place this characteristic in the foreground, though for me it has always been very reliable. The other two symptoms, on the contrary, are une. quivocal, and briefly expressed are as follows:—first, the mucous membrane in a cancerous growth is firmly con- nected with the underlying induration and immovable over it, which is not the case in mere hyperplastic thick- ening and induration; and, second, while the latter, under the pressure of compressed sponge in the cervical canal, becomes regularly (even though at times incon- siderably) looser, softer and thinner, the cancerous infil- tration remains unalterably hard and rigid, and cannot be stretched. What clinical experience has thus taught is clearly explained by a consideration of the microscopic anatomy of the disease; and this compels me to make a short di- gression upon the development of cancer, which is the more in place as all accounts of the origin of the disease labor under the objection of indecision and incomplete- ness, referring, for the most part, to the manner in which it develops itself externally and other matters of only secondary importance; thus Förster's distinction of papillary and parenchymatous epithelial cancer"; the * Handb. der. Pathol. Anatomie, ii. Bd., Aufl. 2. 186 [APR. 20, £872: T. E. H. C. T., T N T. C. division by Blau into cancroid, as villous papillary tu- mor, and carcinoma as uniform infiltration of the deeper layers of the cervix;* and Gusserow’s omission of any decided opinion upon the subject.f The results of Waldeyer's investigations, which my colleague has kindly permitted me here to anticipate, help us to a clear and satisfactory explanation of the observed phenomena. He shows that cancer of the cervix uteri is developed from the rete Malpighi of the mucous membrane, or, in extremely rare cases, from the glands of the cervical canal. The latter form of devel- opment gives rise to the alveolar or colloid carcinoma, and is, as remarked, so extremely rare that Waldeyer has had but one opportunity of examining a case of the kind. I also have seen but one. He can, there- fore, accept the form originating from the rete Malpighi as the type of carcinoma uteri. As a rule, the disease is developed from the interpapillary depressions of the epithelium, and accordingly originates oftenest on or close by the lips of the os, but may, of course, appear in other places free from papillae. According as the growth of the epithelium into the tissues below is or is not attended by a simultaneous growth of the papillae, two forms of cancer may be dis- tinguished—the papillary villous (commonly called cauliflower excrescence) and the simple infiltrated form. In every case, however, the irregular epithelial growth remains the essential part of the disease. + * % •k * Since the development of cancer always begins with the abnormally rapid growth of the deeper layers of epi- thelium, it is very possible that the disease may be far advanced, even though the superficial epithelial layers remain entirely unchanged. Hence the frequent men- tion of the primary deep development of uterine cancer with an outwardly healthy mucous surface. It is a mistake, however, to fancy the epithelium entirely un- concerned in the process. In many cases, to be sure, and even at an early stage of the disease, the outer layers of epithelium are thrown off, and the beginning cancer is presented in the form of an erosion, as well as an epi- thelial infiltration of the subcutaneous layers of connec- tive tissue. Farther, it is to be remarked that in the uterus, just as on the skin, the cancerous development may start from a small, circumscribed collection of epithelial cells and penetrate hence inwards into the tissue, or extend outwards towards the surface. In the first case, the disease must appear as a small, circumscribed induration (Knoten), lying deep down in the substance of the uterus; in the Second, as the so-called corroding ulcer, ulcus phagedænicum or gorro- dens of authors. If the disease has advanced to marked papillary growths or ulcerous disintegration, the diagnosis is com- paratively easy, but even in the cases in which there is * Eiringer's Pathologische Anatomisches uborder Gobārmutterkrebs. i Loc. c it. externally no disease, the immobility of the mucous membrane must be recognised as a condition in perfect conformity with the established facts in regard to the development of carcinoma. Since the carcinomatous indurations and infiltrations owe their origin directly to the most important constitu- ent of the mucous membrane, namely, its epithelium, and are thus intimately connected with its superficial layers, any motion of the latter upon the new growth is prevented. The different effect of compressed sponge upon car- cinoma and homoplastic induration will be understood if we consider that in the first case the diseased tissues, as if injected with wax, are filled with an inflexible mass, which deprives them of all elasticity and renders them incapable either of being stretched without rup- ture by the mechanical pressure of the swelling sponge, or of being softened by the fluid fluxion and exudation which the sponge indirectly incites in other conditions of structure. In fact, these two effects of compressed sponge corres- pond exactly with the two conditions accompanying labor, viz., the pressure of the advancing foetus and the attending hyperaemia; and it was, in fact, this last com- parison which led me to the idea of using the sponge in the way indicated. | My first case was that of a patient whose irregularly indurated, enlarged, fissured cervix uteri had frequently been held for cancerous and its extirpation recommended, The absence of carcinomatous hardness, however, and a mucous membrane entirely normal, and easily movable. except at the fissured points, arroused in my mind a doubt of the correctness of the diagnosis; and every idea of carcinoma disappeared when, the next day, after the introduction of a compressed sponge, I found the indurated and thickened portion much softer and thinner. The latter history of the case confirmed the correctness of my diagnosis. I have very often since argued in this way the absence of cancerous disease, and subsequently proved the justice of my conclusions by microscopic examination after removal of the inflamed and hyperplastic vaginal por- tion (an operation which is attended with immediate benefit, and is in itself without danger). If, as is true, the opposite cannot be so often proved, the difficulty lies only in the frequency with which cases of primary parenchymatous cancerous disease without papillary hypertrophy of the mucous membrane are observed in the beginning of their course. I have met with but two cases of the sort in all, but in both, the signs in question proved their reliableness as criteria for the differential diagnosis. It may be objected to the use of the compressed sponge as an aid in diagnosis, that by its means the de- generation of the neoplasm, the exulceration of the cancer, will be hastened. That I allow; but, still, there is no harm done, for the extirpation must follow imme- diately if the disease is ſound to be carcinoma. It is APR, 20, 1872.] only when done very early that the operation can be at- tended with any success; and whether a perfect cure ever results, I still very much doubt. For, even in the two above-mentioned cases, in which I recognized the disease in the first stage and -operated, so far as the finger could judge, in healthy tissue, the operation was useless. The disease returned almost immediately. The result was the same in three other cases with ulcerations and superficial growths, in which I applied the galváno-caustic wire upon a ring of apparently yet. healthy tissue close up to the vaginal attachment, where, to be sure, the burned cut surface did not allow micro- scropical proof of transition to healthy tissue. In the first case, the wound healed well and showed no change for nearly a year, when suddenly a papillary cancerous growth developed itself with surprising rapidity from the cicatrix. In the second, new papilloma showed itself immediately upon the falling off of the slough. In the third case, after long suppuration and repeated slough- ing, a tunnel-shaped cicatrix was formed in the base of the vagina, with which the cervix uteri was closely con- nected, and I considered the case cured. Upon exami- nation, a year and a half after the operation, I found the cicatrix unchanged; but at present, three months later, there is developed upon the site of the old disease a superficial cancerous induration larger than a pea. Nevertheless, I must still allow the possibility of a radical cure by early amputation. It is confirmed by the reports of perfectly reliable authors, although there are among those reported many cases of only apparent cure. Certain it is that cures are very rare, and the reason for it is probably to be found in the rapidity with which the lymphatic vessels in the neighborhood of: cancer, in contrast to sarcoma, are invaded by the dis- ©a.Se. In the very great majority, however, of cases of carci- noma of the cervix, amputation is inadmissible. On this point I differ completely from Gusserow's too gen- eral advice” for operation. The loss of blood upon the application of instruments and the removal of the diseased portion, is so considera- ble that it injures the patient more than the temporary retardation of the growth and ulceration can benefit her. It has always seemed to me that the disease made more rapid advance after the bloody operation, and that the degeneration and disintegration became only more rapid. If the disease is locally far advanced, the removal of the diseased portion must be accomplished with scalpel and Scissors, if there is to be any prospect of a respite of even a few months. For it is with these instruments alone that it is possible to extirpate a pyramidal-shaped piecet whose apex shall extend above the base of the Vagina, which level in a case anyways far advanced is *— —º TIEEE TH} C.T.I.N.I.C. of authority favored the latter. * Loc. Cit. t Hegar-Werhand. der Gynäkol. Section der Naturforscher-Vers- ammlung zu Innsbruck. Mon. für Geburtsk 34 Band, S. 394-95. 187 always overstepped in the vicinity of the cervical canal. Loop and chain cannot be operated above this level, must cut, therefore, through the midst of the disease, and the following development from the cut surface is all the more luxuriant. For a while, I deceived myself with the idea that, in cases where the vaginal walls were not yet attacked, it would be possible to remove a portion of the corpus uteri by means of a wedge-shaped incision, but the difficulty of the undertaking became evident upon the first attempt at its execution. The enormous haemor- rhage, the impossibility, in the gushing blood, of con- trolling the instrument by the eye; the necessity of di- recting scalpel and Scissors in the narrow space with the fingers alone; the danger of injury to the neighboring parts (bladder and especially peritoneum); the repeated tearing out of the hooks fixed in the brittle mass; then, too, the threatening danger of serous inflammation which would attend the tamponning or cauterization of the bleeding wound—all caused me to regard the comple- tion of the operation, without imminent danger to the life of the patient, as impossible. My advice, therefore, is: very early operation, or, where this is not possible, mere treatment of symptoms. —-º-O-º- A C A D E M Y O F MIE DI C IN E. JAS. GRAHAM, M. D., PREST., L. WOLF, M. D., SECTY. Transactions April 13, 1872. Reported by Joseph Ransohoff. *-*-*s- Regular session; the President, Dr. Graham in the chair. Dr. Thomas Kearney presented a paper on syphilis. He opened by reviewing the theories of the unicists and dualists, stating at the same time that the weight The essayist then di- rected the atteneion of the Academy to Morgan's views, viz., “That the soft, non-infecting sore in the male is produced by inoculation from a secondary syphilitic lesion, and particularly from the vaginal Secretions of infected females.” The author objected to these views, because Morgan's experiments were made exclusively upon prostitutes, and hence the fallacy of some of his conclusions. He then briefly referred to the difficulty of diagnosis by physical appearances alone between the infecting and non-infecting sores, and then quoted from the report of the committee appointed by the Parliament to investigate venereal disease in the British army. The report stated that “It could not be known with certainty whether or not a local sore would produce con- stitutional syphilis until the constitution is actually in- volved.” Dr. Kearney then referred to the practice of syphilisation which corrected the belief in the non-inoc- 188 [APR. 20, 1872. TIEEE IH, C T I INT I. C. ulability of syphilitic sores upon the persons bearing them. In the treatment of syphilis, authorities differ but little. Mercury is almost universally given in the earlier stages, and certain salts of Iodine in the tertiary stage. The author thinks that mercury should not be given until some constitutional manifestations of the virus appear. Lee says “that the insufficient use of mercury renders the subsequent developments more difficult of control, than if no mercury had been given.” The essayist concluded with the report of a case of syphilitic dementia, treated succesfully by Dr. Henry of New York. In this case from 90–300 grs, of Potass. Iod. were given in the course of twenty-four hours. Dr. Carson presented a pathological specimen to the. Academy. It was a lung, removed from a patient who had been suffering with phthisis of four years duration. According to the patient's statement, it had originated in a severe cold. The case was interesting because it presented some peculiar physical signs. A year previous to his death, the patient exhibited a very marked con- traction of the right side of his chest. By percussion a dull sound was elicited, expansion was diminished and respiration in the anterior region of the right side was tubular. At no period were there any evidences of the existence of cavities. The patient died suddenly, the cause of his death being pericarditis with effusion. The apex of the right lung presented a very large and ragged cavity in which the remains of a vessel were to be ob- served. Cavities varying in size and bounded by fibroid tissue are dispersed throughout the entire right lung. The pleura is everywhere thickened and especially at the base where it is fully half an inch thick. The left lung presents no cavities but is thickly studded with granulations, and also shows a tendency to fibroid de- generation. In this case the speaker had experimented upon the anti-pyretic effects of quinia. His average temperature in the morning was 98.3°F. The evening temperature ranged from 99%% to 101°. He was then ordered xx grs. Quin. Sulph., every morning. Although he continued this treatment for 11 days, accurate ther- mometric observations showed but little alteration from the average temperature previous to the administration of the agent. The speaker had also given quinia in a similar manner in another case of advanced phthisis, whose average temperatures were 98}* and 103}” in the morning and evening respectively. In this case the re- duction was also very slight. He had also given 120 grs, of quinia in two days in a case of typhoid fever. In this instance the fever was considerably reduced but the speaker attributed the reduction to a natural decline of the fever. These experiments, though not con- clusive, showed in the speaker's opinion that the anti- pyretic power of quinia was greatly over-estimated, especially when given in 1 or 2 gr. doses, and at longer intervals. —º-e-ºn- THE world is moved by the men of uneasy soul.— Hawthorne. MEDICAL NEWS AMIERICAN MEDICAL Association. Active measures are being taken by the medical pro- fession of Philadelphia to insure a pleasant visit to their guests at the ensuing meeting of the American Medical Association. The programme, as now arranged, com- prises a reception similar in character to the one given in May, 1870 (see Med. News, June, 1870, p. 90), by the Biological Section of the Academy of Natural Sciences, and a promenade concert at Horticultural Hall on Tues- day evening, May 7th. On Wednesday and Thursday evenings, in addition to the usual private entertainments by citizens, there will be given very interesting lectures on the spectroscope, gas microscope, the recent discov- eries in electricity and galvanism, etc. And on Friday the members of the Association, with their ladies, will make an excursion to Fairmount Park, and along the banks of the Schuylkill. A visit to the iron-clads at Leagué Island is proposed. The Alumni of the University of Pennsylvania and of the Jefferson Medical College will each avail them- selves of the meeting being held in Philadelphia to have a reunion. During the sessions of the Association there will be held in the Hall of the College of Physicians an exhibi- tion of objects of interest and instruction, such as recent inventions and improvements in surgical and obstetrical apparatus and appliances, optical, ophthalmological and other instruments of precision, philosophical and elec- trical instruments and apparatus, new chemical and pharmaceutical preparations, anatomical and pathologi- cal specimens, models and other means of illustrations, and new books, prints, and other publications. The chief design of this exhibition, which it is hoped will be held annually hereafter, is to show the recent progress in, and present status of, these respective branches of knowledge and industry. We earnestly hope that gen- tlemen who have objects of especial interest or recent origin, in these different classes, at their disposal will at once avail themselves of this opportunity to bring them forward, not only for their own benefit, but for that of the profession generally. Contributions are invited from all parts of the country. Any information wished by gentlemen desiring to exhibit may be obtained by addressing Dr. Wm. Pepper, 1215 Walnut Street, Dr. F. F. Maury, 1218 Walnut Street, Philadelphia.-News and Library, April, '72. THE EMPEROR OF BRAZIL.-The Emperor of Brazil while at Paris visited Dr. Wecker's ophthalmic clinic, which he has recently established in his new and mag- nificent quarters in Rue du Churchemidi. He was present at Some operations and ophthalmoscopic demon- strations and complimented the Doctor very highly on the excellent appointment of this house. APR. 20, 1872.] TIEI IEI, CT I INTI C. i89 w— —r- • THE MEDLICOTT CASE,--The Supreme Court set aside the verdict in the Medlicott case, , and ordered a new trial, mainly on the ground of the lower court admitting, as testimony, the dying statement of Ruth, the murdered, man,—Leavenworth Med. Herald, April, 1872. & t BoDND IN HUMAN SKIN.—A copy of the “Constitu- tion of the French Republic of 1794,” bound in human skin, is about to be sold in Paris. The binding, however is said not to be unique. The public library in Bury St. Edmunds contains an octavo volume, consisting of a full report of the trial and execution of Corder—who, it may be remembered, murdered a young woman named Martin, at the red barn, in a neighboring village, about forty years ago—together with an account of his life and other matter. This volume is bound in the murderer's skin, which was tanned for the purpose by a Surgeon in the town. The skeleton was prepared for the Suffolk General Hospital, and is still to be seen there. The human leather is darker and more mottled than vellum, of a rather course texture, with holes in it like those in a pig's skin, but smaller and more sparse. English books with this kind of binding are at the same time much less rare than is generally supposed. In the Bristol Law Library are several books bound in human skin, specially tanned for the purpose, and some curious de- tails might be furnished of several local culprits execu- ted in that city who were flayed after execution to furnish the leather for binding together some contem- porary legal lore. w BELLEVUE HOSPITAL MEDICAL COLLEGE.—The fol- lowing changes have lately been made in the Faculty: —Prof. Stephen Smith has resigned the chair of Descriptive and Comparative Anatomy, and Clinical Surgery, Prof. B. W. McCready has resigned the chair of Materia Medica and Therapeutics and Clinical Medicine, and has been appointed Emeritus Professor of Materia Medica and Therapeutics and Professor of Clin- ical Medicine. Prof. A. B. Crosby has been appointed Professor of General, Descriptive, and Surgical Anatomy. Prof. Wm. A. Hammond has been appointed Professor of Materia Medica and Therapeutics, Diseases of the Mind and Nervous System, and Clinical Medicine. Prof. Hammond will continue his lectures and clinics on Diseases of the Mind and Nervous System as heretofore, lecturing also upon Materia Medica and Therapeutics. Dr. E. G. Janeway has been appointed Prof. of Path- ological and Practical Anatomy. As Prof. of Patholo- gical Anatomy, he will deliver in the regular session a course of lectures on that subject. As Prof of Practical Anatomy, he will perform the duties of Demonstrator of Anatomy, Dr. E. L. Keyes, formerly Lecturer on Permatology, has been appointed Prof. of Dermatology. Prof. A. B. Mott has been transferred from the chair of Surgical Anatomy, with Operative and Clinical Snrgery tº the chair of Clinical and Operative Surgery. Prof. Mott will relinquish his didactic lectures on Surgical Anatomy to the Prof. of Anatomy, and will hold a Sur. gical Clinic at the college throughout the year. UNIVERSITY MEDICAL COLLEGE N. Y.-Dr. Joseph W. Howe has been appointed clinical Professor of Surgery; Dr. Henry S. Hewit, Professor of Clinical Surgery; Dr. Arnold, Professor of Pathological Anatomy and Dr. Kammerer, Professor of Diseases of Women and Children, vice Dr. F. D. Lente, resigned. PHILADELPHIA HospitaL, BLOCKLEY.—Prof. A. Stillé has resigned his office as visiting physician to this hospital, and the managers have passed a resolution thanking him for the efficient services rendered while connected with the institution. Dr. J. Tyson has been elected visiting physician in place of Dr. Stillé. CLOSURE OF THE PARIS SCHOOL.—The Paris Medical Students have again made use of political motives in demonstration against one of their professors, Dr. Dol- beau, professor of surgical pathology. To put an end to such scandalous scenes the faculty have concluded to entirely close the medical school of Paris for one month, that is, to the 'énd of April. LostORFER's SYPHILIS DISCOVERY.—The discovery of germs in the blood peculiar to syphilis was published, as is well known, in the Vienna Medical Press, Jan. 28, 1872. In the very next number, Feb. 4, 1872 the fol- lowing letter appeared in large type. LOSTORI FER2S SYPHILHILIS BOLDIES. To the Editor of the Vienna Medical Press. The importance and significance of the preliminary communication on the alleged syphilis bodies published in your valuable paper (Jan., 1872, No. 4) determine me to request you to accept the following lines in ex- pression of my views upon this subject. The so-called syphilis bodies occur in normal as well as in syphilitic blood and are, so far as my observations hitherto extend, nothing else than protoplasm and fat particles which obtain their so-called vacuolae from the escape of the water of the process of decomposition developed in the water chamber. They are, therefore, by no means to be regarded as a specific characteristic of syphilis. Most Respectfully, Prof. C. Wed]. Vienna, Jan. 30, '72. —º-º-º- CORRESPONDENCE. CINCINNATI, APRIL 11, ’72. EDS. CLINIC: I notice in a late number of one of the Journals what purports to be the formula of “Dr. Jackson's Cough Syrup,” as adopted by the Cincinnati College of Phar- macy. As it does not answer the original prescription, 190 T. EEIL TED CT, ITNT.I. C. ... ---------- * *-***** [APR. 20, 1872. I send it to you, as I find it among my father's papers and as furnished by Dr. Jackson. R. Syrup. Morphiae, 3ij. “ Ipecac et Senekae, “ Rhei Simplicis, & 3i. M. S. A Tablespoonful three times a day. The Syrups of Morphia, of Ipecac and Senekae are pre- pared thus. 1st. R. Mur. Morphide, gr. Syrup. Simpl., 37. Ol. Sassafras, 9ii. R. Rad. Senekae, 3ij. Ipecacuauhae, 3i. Aquae Font., gal. #. 2nd. Boil the snake root in the water until half consumed, then add the Ipecac and from one to two pounds of Sugar. Respectfully, C. O. WRIGHT, M. D. ——sº- © CLINICAL MEMORANDA. MIenstruation from the Mammae. BY Dr. P. MYNET. Physician to the Charite, From the Lyon Médicale, Mar. 17, ”2. Henriette M–, aged 17, well formed, though of lymphatic temperament entered the Hotel Dieu (Lyons), Salle St. Charles, Feb. 24, 1862, with the statement that for the past eight months her menses had escaped every month through a fissure in the nipple sometimes of one side, sometimes of the other. The loss of blood was sufficiently abundant and continued for two or three days. This hemorrhage is preceded each time for a day or two by pain and swelling of the breast. When it ceased the fissures of the nipple closed, the breast soft- ened and in every way she was well. She had never had her courses, but during the time of hemorrhage from the breasts she experienced slight pain with a sense of fullness in the abdomen and lassitude in the loins. Her general condition was excellent. We had the opportunity of observing the phenomena mentioned on three separate occasions. The hemorrhage occurred and passed with the greatest irregularity. The breasts were manifestly swollen and painful, the nipple was sur- rounded with a small black circle and at its extremity from a rough, anſractuous surface there oozed a few drops of perfectly red blood. The daily quantity lost was about 30–40grammes. The duration varied between two and three days. Subjected to a tonic treatment of iron and bitters during her stay at the Hôtel Dieu with at the same time an attempt at restoration of the hemorrhage per vias naturales by cutaneous and intestinal revulsives, sinap- isms and purgatives and cups over the loins repeated two or three times, she left the hospital in unchanged condition. Two months after exit the menses appeared naturally and there has been since this time no return at the breasts. t I have again, quite recently seen this young woman and this is the occasion of the present memoire. She is now 27 years of age, robust and vigorous, but menstrates irregularly, every two or three months, with much pain about the abdomen and kidneys. She has an intercostal neuralgia which manifests quite frequently and occasional palpitations. In a word, she presents numerous signs of chlorosis but without the bruit of vas- cular souffle. Married for three years, she has never borne a child. [The author then appends another somewhat similar case in a woman of 44 years, robust and of sanguine temperament, the mother of two children. It terminated in an active inflammation of the right breast which is increased at every epoch and which has hitherto resisted medication. So far there is no indication of cancer from this manifestation which is regarded by some authors as one of its first signs. He cites in conclusion the two ob- servations of M. Duchaussory, communicated to the Society of Practical Medicine, November, 1871; cases of hemorrhage from the nipple, in neither of which did carcinoma appear. In one of these cases the injection of tincture of iodine into the galactophorous ducts suf- ficed for cure]. REMOVAL OF FOREIGN BODIES FROM THE EAR BY AGGLUTINATION.—Löwenberg, of Paris, calls attention in a long article (in the Berliner Klin., Woch., Mar. 4, ’72,) to his “agglutinative method” for extracting for- eign bodies from the ear, giving illustrative cases. He objects to the use of syringing with warm water both when the foreign substance completely fills the ear, and also when there is a perforation of the membrana tym- pani. In the latter condition one runs the risk of driving the foreign body into the cavity of the drum. He uses ordinary glue, dropping it upon the foreign body and waiting fifteen minutes for it to cool and harden. [The subject of foreign bodies in the ear is one that under some circumstances may become of vital interest. It is surprising what difficulties various operators get themselves into, and remarkable to relate, the only serious cases, in fact the only difficult cases that have come under my care, have been made such by previous manipulations. A curious chapter of expedients might be given, showing the difficulties in the way of removal of foreign bodies among the older practitioners and some among the more recentl. APR. 20, 1872.] Tº H. H. C. T., T N T C. 191 AN INTRA-UTERINE INTERMITTENT POLYPUS.— Certain intra-uterine polypipresent the remarkable pe- culiarity of engaging at the os during menstruation and protruding thence into the vagina. After a variable time they withdraw themselves again into the body of the uterus and reoccupy their first position. Their presence in the vagina, thus, is transitory and intermit- tent. Such a case recently presented at the Maison Princip. de Santé in the service of M. Demarquay. Bernardeau and several English surgeons have published facts of this kind. In France, Sabatier, Marjolin and Lisfrance have already signalized the influence of men- struation on this class of tumors. M. Demarquay has observed three cases in his practice published in the memoire of M. Larcher in the Archives de Médicine. This paper includes several original observations and existing knowledge on this subject. In the case of the text the os was dilated with sponge tents and the polypus was secured and removed.—Gaz. des. Hopitaua, Feb. 24, '72. —-º-º-º- Cold Applications in Hyperpyrexia. Clinical Society of London. From the Brit. Med. Journ., Mar. 30, 1872. Dr. Hermann Weber read a paper on a case of hyper- pyrexia in rheumatic fever, successfully treated by cool baths and affusions. The patient was a youth aged 16, who had rheumatic fever (first attack) in August 1871. The affection of the joints was well marked, but not excessive. The temperature of the body varied between the ninth and twelfth days of the disease from 101.6 to 102.2 deg. Fahr.; the pulse between 98 and 118; the respiration between 20 and 24. The lungs were free, and there was only the slightest indication of a murmur with the first sound near the apex. The medicinal treatment consisted of three grains of quinine three times a day. On the morning of the thirteenth day, great restlessness, vomiting, excessive micturition, involuntary motions, delirium, tendency to coma, and lividity of face, Supervened, simultaneously with a rise of temperature from 101.6 deg. on the previous evening to 108.2 deg., of the frequency of pulse from 118 to 148, and of respira- tion from 22 to 56. The patient was then placed in a bath of 71 deg. E.; and affusions of water of the same temperature were made. The mental condition and the appearance of the patient rapidly improved already during the first ten minutes; and at the termination of thirty minutes, when he was removed from the bath? the temperature in the cavity of the mouth was only 101.8 deg, while the patient fell asleep, and began to perspire freely. In the course of the same afternoon, the temperature again began to rise rapidly—i. e. from 100.8 deg, at 8 P. M. to 105.8 deg. at 6.40 P. M. Pulse 148; respirations 38; slight delirium. The patient had then another bath with affusion, as in the morning, when the temperature further arose during the first five minutes of the bath to 106,2 deg., but afterwards fell rapidly, the mercury receding within twenty-five minutes (the duration of the bath) to 101 deg. After the second bath. without any medicinal or hydro- therapeutic treatment, the disease took the course of a usual mild form of rheumatic fever, leading to perfect recovery, leaving only a rather too long first sound. Dr. Weber repeated the view stated in a former communca- tion to the Society: that the nature of these attacks was the same as in common heat-stroke or insolatio; and he thonght the term hyperpyrexia, as employed by Dr. Wilson Fox, more appropriate than heat-stroke, which conveyed the idea of causation by external heat. Acknowledging that hyperpyrexia was an accident which could occur in all febrile diseases, he maintained that it occurred infinitely more often in rheumatic fever than in any other disease; and, regarding the peculiarities of rheumatic fever, he was inclined to ascribe it to the tendency to endocarditis and fibrinous deposits existing in this disease. He suggested that it might have a sim- ilar origin with chorea, and might possibly be due to minute embolism or to plugging of some small vessels in a certain portion of the nervous system, as the hypo- thetical centre of animal heat and chemical changes. As to prognosis and treatment, he pointed out that all cases formerly had a fatal termination when Once the temperature had reached 108 deg. Fahr.; but that the hydrotherapeutic plan, ifearly and energetically pursued and with watchfulness as to the possibility of several attacks, gave great promise of a speedy cure, as had been shown by the two complicated and yet suc- cessful cases published by Dr. Wilson Fox, the one by Dr. Medling, and the one by the author. Dr. Hermann Weber alluded also to a difference in the action of the cold baths in this class of cases (hyperpyrexia) and in the pyrexia of typhoid or enteric fever, typhus, and other fevers of longer duration. While in the latter the baths, when given during the height of the disease, pro- duced only a transitory reduction of temperature, which was followed sooner or later by a fresh rise, so that three, four, or even five baths might be required on each of several successive days, in the hyperpyrexias one or two baths might be sufficient entirely and finally to remove the complex of symptoms within less than twenty-four hours. He thought that this difference in the action of the plan in question pointed to a difference in the un- derlying pathological causes.—Dr. Greenhow gave details of a case which had been under his care in the Middlesex Hospital, and in which the cold application did marked good, although the patient ultimately died, the treatment not having been, by some unforeseen accident, continued. The result of the treatment in this case, and in another under his care of high tem- perature in typhoid fever, had led him to entertain a high opinion of its therapeutic value.--Dr. Andrew 192 [APR. 20, 1872. In IEEE IEH C T I I INT I C - asked Dr. Greenhow what treatment had been adopted before the high temperature supervened, as the condition might be due to the remedies.—Dr. Greenhow, in reply, stated that the treatment had been by alkalies, and that he believed the patient was ordered one large dose of quinine on the morning on which the high temperature was first observed.—Dr. Wilson Fox observed that the high temperature had nothing to do with the treatment, and brought forward facts which had occurred under his own observation to prove what he said. From his ex- perience of the cold treatment in hyperpyrexia, he was able to speak strongly of the good results to be obtained from it, and earnestly urged its being carried out in private practice. It was a matter of life and death, and medical men should not hesitate to carry it out. No case, except one of relapsing fever, had been recor- ded in which a patient with a temperature of 108 deg. had recovered, unless by the cold treatment. He did not think that cooling of the skin could unload plugged capillaries.—Dr. Anstie observed that hyperpyrexia might occur in any complaint, and alluded to a case of delirium tremens under his care in which the tempera- ture was 109 deg., and the pulse was shown by the sphygmograph to be undulatory in its character, Dr. Southey said that, without accepting the theory of plugging of arteries, stasis in the vessels might be present and be removed by the cold applied to the skin.—Dr. A. P. Stewart was of opinion that these cases were not dependent on plugging of the minute vessels. In one case which had been under his care, the temperature had risen to 109.5 deg., and the blood was found more completely fluid than in any case of typhoid or typhus fever he had ever seen. This militated against the view of plugging of the vessels. This class of cases presented a typhoid type from the commencement: in fact, some people would say, from the appearance presented by the patients, that they were laboring under typhus fever. All the cases he had seen were given colored water, so that remedies could not have caused the hyperpyrexia. He considered the plan advocated by Dr. Weber to be a very admirable one,—Dr. C. J. B. Williams thought that, in these cases of hyperpyrexia, there must be some affection of the nervous system from the commencement something affecting the heat-making process in the body, causing it to rise to a fatal height. He doubted the safety of hastily adopting a form of treatment like this. In continued fever, it was useful; but in rheumatic fever there was inflamation of the joint, and this might be repelled from one part to the other. He, in his long experience, had never met with a case of hyperpyrexia; and he had only two deaths from acute rheumatism during the ten years he was physician at University College Hospital—one from double pneumonia, and one from valvular heart disease. After offering some re- marks on some of the modes of treatment of rheumatic fever, he expressed his opinion that the hyperpyrexia might perhaps be due to treatment.—Dr. Weber in reply, said that he would not usually treat acute rheu- matism with cold water; but the examples of high temperature were cases of life and death; and by its means the duration of the disease was shortened, and also its mortality. *~~ *~. ~. MORPHIA AND CHLOROFORM CoMBINED.—M.M. Labbé and Guyon recently read a paper at the Acadé- mie des Science, in which they gave an account of the results obtained in four cases in which they had tried the combined effect of hypodermic injection of morphia and the inhalation of chloroform. They were induced to enter on the investigation by having observed numer- ous experiments of M. Claude Bernard at the College de France, which demonstrated that, by such combination, very complete anaesthesia may be obtained by means of a much less quantity of chloroform than when this substance is employed alone. About the same time that M. Bernard was pursuing these researches, Professor Nussbaum, of Munich, with a view to the prevention of the pain consecutive to operations, injected in several cases the acetate of morphia while the patient was under the influence of chloroform. In all his cases pain continued suppressed, and Sound sleep was prolonged for several hours after the operation. While Professor Nussbaum, however, employed the morphia during the anaesthesia, MM. Labbé and Guyon injected it before this was produced, their object being also different—not the prevention of consecutive pain, but facilitating the production of anaesthesia and ren- dering it less dangerous by reason of the smaller quantity of chloroform employed. At present they have only resorted to the means in the four cases, abstracts of which they now lay before the Academy. In the first of these, twenty minutes before the performance of an amputation, two centigrammes of muriate of morphia were injected into the thigh, and then chloroform was administered. In seven minutes anaesthesia was com- plete, and was prolonged for a long time after the operation, which lasted seventeen minutes. The quan- tity of chloroform employed was twenty-eight grammes. In the case of ovariotomy, occurring in a girl of 20, the chloroform was given twenty minutes after the injection, and complete anaesthesia was produced in six minutes. The operation lasted an hour and forty-five minutes, and the expenditure of chloroform during all this time was only forty-eight grammes. The patient continued in a state of complete relaxation, and after the operation, was entirely calm, having felt no pain whatever. Incomplete as are their researches at present, the authors feel entitled to conclude: first, we can in man—as M. Claude Bernard has shown can be done in animals—obtain anaesthesia much more rapidly by combining the action of chloro- form and morphia; secondly, that this anaesthesia is of longer duration, and may be kept up by smaller doses of chloroform, the risks of fatal accidents being thereby considerably diminished. They suggest also that the quantity of morphia injected may be somewhat larger than that which they employed, and that the injection might be conveniently practised a longer time before the operation.—Times and Gaz., Mar. 23, '72. . ‘s • * * J. " 2 \, *> - - DIVIDED MEDICINES, ~ * , . . . . . . . . . . 5 … • t & . . . ; * . . . . . . . ; ". x - - 3 - - - º sº *. * : * . . . . . ., - : Tºº,” .” - - ** ..". 3 * ;3 * - . - 4. & . $3.3 *" •. - A ... * … . . . . ; * * º ******* - .* t *:: *. - ..” - . 3. • ,-" “. . … -- ~~~~ • *.* . - - ~ * - **. - .* . - * * +& $...y - - - - . - • . , sº ºf : * , . . . ~ * ; : ‘. . . A - s ; : « . - - - .. & *.* ! *. . . . . t . . . ; ) is ºf º' & . . . ; # , ºf . . .''. ‘. .* . . . . .. * 3 , - - - . ...- : * ~ * . . ." ‘. . . . . * * * * * * . . . * : º * “ . . - - * . . . . * . - , - . - . . . . . . . . . . . . . . . - - - \ … <2< ... . . . . . .* “, 3 . . . . . - * . . . * * : *- : . * * * * - - - ... ." * - ...--~ * . - * - - s - ...*.* ºr jº. 2 . . . .” rºl. **.* **** . . . ~~' s -- * *-* *- : . . . * - - - - -- - **. * r - - - . . . . . ... ' t ... . º's * O & O O , . .” •. t - - . . . & - . t; k - • ". ... . - f - " . . . ; & x - . . ~~~ * ~ * • - - - . . - "... • * . ‘. - r # •. - - - - - - § - jº .. • *. - - '. ** - * . : a .” ‘. . . ar . . * : : : - •- * = . . . . . - - - O->- * ... The Company have the honor of bringing to the notice of the Profession, this New AND ExcLEDINGLY PRACTICAL METHod of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. d The Divided Medicines are prepared by FREDERICK KRAUs, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MORE. - The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every square will consequently contain accurately measured quantities. . .. But not only SoLUBLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINEs. - -- -- *. *. . .2 This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, # , , , º, and even ideo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. - . . . Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE TO SPOIL BY ANY LENGTH OF TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calls with good accurately dosed medicines; and that these médicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. . . For samples, Price Lists, and Agencies, address - The Di TECIX 2688, Or FRFDERICK KRAUS, Chemist and Druggist, . . . . . Walnut Hills, Cincinnati, O. § —tº * – w Mr. FREDERick Kraus: CINCINNATI, February 15, 1871. - - Dear Sir—The specimens of your “Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: - - > - SULPH:MORPHII....................... * … . quare. Arsenacio… .1-20 grain i *śºstºn inºchºre. # - §: grain in each square. 46 COPPER w is º ºs º is e e * * * * * * * * * * * * * * g. .3% - te - - - - - - - ResPEGTFULLY YoUBs, E. S. WAYNE, Analytic Chemist. *a Carriage Manufacturer, NOS, 9 and 11 East Sixth Street, bet. Main & Sycamore. 82 . I MAKE NOTHING BUT: First czass wronx. Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of LIGHT FAMILY CARRIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive variety of light elegant designs of different cost and finish. In vehicles especially PHYSEEFANS” {{SE, The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. adapted to The superiority of my light gentlemen’s buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price lists furnished on application. References to Dr. W. W. Dawson and all the leading £hysicians in the city and fielghborhood. 83 77 ſ\}.Sk Wm. Wilson McGrew, JW2, 2% WºSA" Aſozºzºz Szºz, PIKE'S OFERA, HOUSE BUILDING, In porter and Dealer Diamond and Gold Jewelry, > Watches for Ladies and Gentlemen, Sterling Silver Tableware, Bronzes, Antique and Modern; Marble and Bronze Clocks, Marble Statuary, FAN cºr Coops, G E N E R A L L Y. WILson BRD's. "VV"AN" ºr )—AGENTºš. S HIRTS Made to order of N. Y. M. Muslin and 2300 HEAVY Linen, per dozen - - - $26 00 Wamsutta Muslin and 2100 HEAVY Lin- en, per dozen - - - - - - - - 33.00 Wamsutta Muslin and 1900 Linen, per doz. 30.00 Lonsdale Muslin and 1700 Linen, per doz. 27.00 First three qualities have ALL LINEN Cuffs and Neckbands. At above prices Cuffs are attached. Same quality of our own manufac- ture, ready-made, $3 per dozen less. Perfect satisfaction given or money cheerfully refunded. - Also import and Manufacture Men’s Furnish- ing Goods. Pike's Opera-House, Fourth Street, Cincinnati; 931 Wabash Avenue, and SS West Washington Street, Chicago. CAM.A. R.G.O MANUFACTURING COMPANY., MANUFAOTURERS AND IMPORTERS OF AND Window Shades, 67 Wasz Kotºzº Szºzzº, CINCINNXT, O, } %. H. H. answevas, Proprietor. - School Teachers, Students AND OTHERS, Can find light and healthful employment for the Summer, by engaging in the sale of our valuable and very popular works. One lady teacher just commencing work for us, reports her net profits for last week at FoETY DOLLARs—many others doing equally well. Large commissions or liberal salary as preferred. For particulars, address NETTLETON & CO., 161 Elm Street, CINCINNATI, OHIO: P. S.—We will make “SPECIAL TERMs” to medical stu- dents, who are “working their own way through college.” º BASEM & CARTENTER, Stationers, Printers -AND-, Blank Book Manufacturers, 136 VINE sºlſ|[REET, &\\\\\\\\\e IE. De ALBIRO & BRO. IMPORTERS AND MANUFACTURERS OF FOREIGN and DOMESTIC WOODS In Veneers, Boards and Plank, frtaint-Maºri','l'-Büller'anishi-BiºWº. The only house in the Western country that saws Spanish and Mexi; can Cedar for Cigar-Box Makers. We import our own wood direct, and can sell at prices to compete with any and everybody. Also saw and keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. Office and Warerooms, 136 and 138 West Second Street, tº: Veneer Mill, 507, 509, 511, 513 & 515 W. Sixth St., CINCINNATI, ----------> *º-º-º-º-º-º-º-º-º-º-º- - * --~~~-- *-*-*-* >– -º- ...” * * *-*-*-*-*- -F - <== ~T-------------4- -º-º- *-m-m-m-m-m-". st-f. === * - “w -*-*- -- - - Aº- - - - <=> ſ—-tº- := aſ E #: 35Eº: ---- £2 T- *-*-*-ºs- zºº *-* *-*-*-ºsm-sº-same-m-m-m-- -----. %5 * *-*-*-*- --~~ -* º: *="------ *-**-*-m-m-m- * …”.” *-*- -*-*-*-* - - ?: 3 -* *-*-*-m-- - - -*. gº -r - - * * == E. – #: *E. --" 25 ====Hºri ſº | É;|| || |*|† iºnſ iſ ºil ill § Eºs º;|--|| | | ### i i. - - sº-tº-3 ==#%: §§º === iºsº % = E-> ====º:5% Ø 2. 2%– º-º-º: ===sºgº % % e- ** *-ºs. - *Z% 22- GooD s AMARITAN HOSPITAL. The GooD SAMARITAN HOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner of sixth and Lock streets. It is handsomely furnished througho", and is provided with all the necessary ap" pointments of a First-class Hospital. Porticoes, with commanding views, surround the whole house, and wide halls and abundant windows secure that full and free ventilation which is so essential to health and comfort. Service is furnished by the SISTERS OF CHARITY, Under the Superintendence of the well-known SISTER ANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. The regular Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each Professor presiding over his own especial department. Patients may, however, select from the regular profession of the city any physician of their choice. The GooDSAMARITAN HOSPITAL presents extra inducements to Invalids throughout the State as a safe and quiet asylum in any case of protracted illness, or in cases, more particularly, requiring Surgical Operation, where some stay is necessary in after treatment. Rooms vary in price, according to the character of appointments necessary and service required, ranging, in general terms, between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand of §eRW1C0. B&" Address, SISTEE, ANTHONY, EIospital of the Good Samaritan, Corner of Siacth and Lock Sts., Cincinnati, Ohio- 3. k jºys ºsºft Kº jº. yº. ºlº iſ F# F.; º *:::, . º ºl. § 2. |. º: : º ſ: | CINCINN ATI. E" A C TU T., T Y. * J A M E S G FR A H A M, M. D., DE AN, IProfessor of the Theory and EPractice of IMCedicine and Clinical IMedicine. ROBERTS BARTHOLOW, M.D., W. W. DAWSON, M.D., Professor of Materia Medica and Therapeutics. Professor of Principles and Practice of Surgery and Clinical Surgery W. H. GOBRECHT, M.D., C. D. PALMER, M.D., Professor of Anatomy. Professor of Medical and Surgical Diseases of Women. P. S. CONNER, M.D., | * . T. A. REAMY, M.D., Professor of Surgical Anatomy. Professor of Obstetrics and Diseases of Children. JAMES T. WHITTAKER, M.D., JOHN L. CLEVELAND, M.D., I’rofessor of Physiology. Demonstrator of Anatomy. SAMUEL NICKLES, M.D., CHARLES KEARNS, M. D., Professor of Physics and Medical Chemistry . º Assistant to the Chair of Surgery W. W. SEELY, MI. D., IProfessor oſ I) is eases of the Eye and Hjar, and Secretary of the Faculty. ** T. LOUIS BROWN, M. D., Prosecutor of Anatomy. E. No BLE, Janitor, College Building, Sixth St., bet. Vine and Race. * Printed and Published by Norn Is & MURRY, Medical College of Ohio Building, Cincinnati. LINIC, PUIBLISHED EVERY SATURDAY. tº RMS-82.00 a Year, Invariably in Advance. An Communications relating to Publications must be addressed to the Editor * * All Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer. Vol. 2. C IN C IN N AT I, A PR, IL 27, 1872. No. 17. º *Lºs * JAS. T. whitTAKER, M. D. - No. 101 West Ninth Street, Cincinnati, -A-SSOCIALT1: E.DITOER.S. W. W. Dawson, M. D. THAD. A. REAMy, M. P. S. Conner, M. D. C. D. PALMER, M. B. W. W. SEELY. M. D. SAMUEL NickLEs, M. D. CHAs. KEARNs, M. B. JNo. L. CLEVELA Roberts BARTHolow, M. D. W. W. SEELY, M. D., . No. 118 West Seventh Street, Cincinnati. D. - - - - - - TREAsvagh. Editor. } j. --- § * * * * , ºr ND, M. D. co-Ary tº ce. hionable Hatters, . HMPQRTERS AND MANUFACTURERS OF EABEES' Fújº S, club RATEs. '92 WEST FOURTH ST. ... • — ` ! : Opposite Post Office, 4 Copies to one address...................................................... $ 7.00 :**** 10.00 CINCININATI. #2 § { * $$ *". sarspecial Inducements to Medical Men. C O N T E N T S - * * • . * - Page. ºf T. Tºp N. ſº. sº, º, . . . . . . . . • , ºr ARIºriºn oRIGINAL ARTICLES ſº iſ ==ºkº º Pibrous Polypus of the Uterus by J. C. Reeve, M.D.........................193 - * ( sº T ſºlº. AN º 3. & Abscess of the Spleen by Philo E. Jones, M. D................................196 º 2. \\ TRANSLArrows - Scurvy, A Report on the Epidemic of Scorbutus in Paris during the Siege (From Schmidt's Jahrb., Mar, 12, 72) - Disease of the Gray Matter of the Cord by Dr. Rosenthal (Front the Wiener Med. Presse, Mar. 31, ’71) * * * *** * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * Jº CADEMIY OF WIEIDICINE Transactions April 24, '72. - $ Tic Doloureux by. Dr. Bartholow—Cerebro-Spinal Meningitis Speci- mens by Dr. Dandridge—Reports of Cases by Drs. Dawson, Carson, Grahama SCIENTIFIC NOTES The Production of Epilepsy in Guinea-Pigs—Influence of Rheuma- tism on the Character—Spasm of the Levator Ani during Coition -The Force of Uterine Contraction 200-202 199 * * * * * * * ME DIGA) A NEWS. High Science—The “Toner Lectures”—Salaries of Germau Profes- Sors—Annottr de la Patrie—The Strasbourg School—The First Med, Journalist—Deaths of Profs, Jackson and Dickson.,..., 202-203 CORRESPON IDENCE - ©hio State Med. Soc.—To the Committees on Special Reports........... 203 CLINHCAI, NIEMI® RANIPA An Important Symptom in Traumatic Paralyses—Treatment of Tetanus by the Chinese–Physiology and Therapy of Alcohol, Coffee, Tea, etc.—Bromide of Potassium in Epilepsy—Benzine in Whooping Cough—Re-implantation of Teeth HOME NEWS *= * * * * * * * * * * * * * * * * * * ſº ****** * * ************ *** *** *** - - - - - - - - - - - ---------- . . . . . . ............ ...... WE have Some new light to- field of spinal patholo g tions of disease of the day over the obscure * gray substance of the cord. The experiments and observations of Westphal leave no doubt as to the existence of central lesions in the so- called reflexe ileptic phenomena of artificial induction. The proceedings of the Academy will be found of especial interest as indicating the presence in our city of cerebro-spinal meningitis. 196]. gy in the recent direct demonstra- * * * * W. T.A.F.T. - Editor, Dental Register a w. TAFT, IDENTTIsTs 17 WEST FOURTH STREET, CHN CIN NATI, O. The Dental Register, A Monthly Journal, al &S CONTAINING 48 PAGES, Devoted to the Interests of the Dental Profession, **. * * * * * * * * * *.*. --~~~~~~ * William Autenrieth, No. 71 wrest sixTH sTREET, BETWEEN WAINUT Añº WIME, CINCINNATi, OHIO, MANUFACTURER OF AND DEALER IN Siſſl Mill iſſºlſ|| |||||||||| Abdominal Supporters, Trusses, 3. CLUB-F00T SHOES, SPINAL APPARATUS, ETſ Keeps constantly on hand a full variety of Metalic and Rubber syringes, Stommºach Puanmps, Etc. ' stockings FoR VARIcose veins. Special attention given to the fitting of Apparatus for Deformities. Bay Agent for DR. L. A. BABCOCK'S silver Uterine Supporter, -ALSO– DR AHL's POROUS FELT SPLINTS, --A 12SO– ID A. Y. * S S P T, IN T S —A N T- | ECHEVERRIA ON EPILEPSY. ... • * ROBERT CLARKE & Co's. List of New Mill, iTºm Mātūn; inſ; GREEN'S PATHOLOGY AND MORBID ANATO MY, 8vo. Cloth. $2 5o DUCHENNE'S LOCALIZED ELECTRIZATION. 8vo. $3 oo DILLENBERGER ON WOMEN AND CHILDREN’S DIS-. EASES. 12mo. $1 75 |BENNETT ON PULMonoRY consumpTION. 8vo. $1 50 FIRST HELP IN ACCIDENTS. 1 amo. $1 5o BEASLEY'S DRUGGIST RECEIPT BOOK. 8vo. $3 go * * * * 8vo. Cloth. $5 oe HOWE ON EMERGENCIES. 8vo. $3 oo HAMMOND ON NERVOUS DISEASEs. 8vo. $5 od RINDFLEISCH'S PATHOLOGICAL HISTOLOGY. $6 oo WARINGS’ PRACTICAL THERAPEUTICS, 2nd Am. Ed. 8vo. Cloth. $5 oc Leather. $6 oo SCUDDER'S SPECIFIC MEDICATION. 12mo. Cloth. $2 56 TANNER'S HANDBOOK OF OBSTETRICS. 12 mo. $2 oo WAN BUREN ON DISEASES OF THE RECTU M. 12mo. - Cloth. $1 5o FLINT'S EXAMINATION OF URINE. 1zmo. Cloth. $1 oo VOGEL ON DISEASES OF CHILDREN. 8vo. Cloth. $4 5o BEARD AND ROCKWELL’S MEDICAL AND SURGICAL ECECTRICITY. 8vo. Cloth. $4 50 ATTFIELD'S MEDICAL CHEMISTRY. 12mo. Cloth. $2. 75 Leather. $3 25 BARTHOLOW'S HYPODERMIC MEDICATION. - Cloth. $1 5o TURNBULL’S DISEASES OF THE EAR. 8vo. Cloth. $5 oa TILT'S CHANGE OF LIFE. 8vo. 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Instrument Makers and Practical Opticians, Beg leave to return thanks for the patronage extended to them through a long series of years (having been established since 1836), and in the reorganization of their firm will endeavor to merit a continuation of the *ame. We wish it understood by the Profession and the Public generally that our invariable rule is, to make or import none but the best in. struments. Those in want of any of the acknowledged good aids of vision to imperfect eyes, will always find the best and largest stock of Lenses, Spectacles, and the best models procurable, with pains. taking skill to adjust them to all conditions of sight, at our house. Special attention paid to orders for Fine Microscopie Objects and Microscopic Apparatus, Magnifiers and Readers in great variety. edical Batteries, Barometers, Thermo- naeters, Hygrometers, Urinometers and Rain Gauges, of the most approved construction always on hand. All orders promptly and accurately filled. JAS. FOSTER, JR. deali F. S SHACKLEFORD, ! *** ** JAs. Fost ER, JR. & Co. S. W. Cor. Fifth & Race Sts., Cincinnati, 0. TXTER, S.INT. TN/I_A_TER,STEI’S Ǻ º Sº No. 758 BRoadway, New Yoak HAVE been in the habit of applying and recommending the Truss I manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined. LEWIS A. SAY RE, M. D. Surgeon, Bellevue Hospital. From Prof. Willard Parker to S. D. Townsend . M. D., Surgeon to the Massachusetts General IIospital. B EG leave to state for the benefit of all coucerned, that I have known 1)r. S. N. Marsh the last fifteen years. I am in the constant habit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have over Been, and his treatment is unattended with an v of the risks to the patient that exist in many of the plans suggested and atteuxpted to be carried into execution. I have confidence in Dr. Marsh as a gentleman of honor aud integrity, and as such recommend him to the members of the medi- cal profession generally. WILLARD PARKER, M. D. Professor of Surgery, New York City Dr. 8. N. Marsh's Patent Radical Cure Truss and all other kinds of Trusses, Shoulder Braces, Supporters, Elastic Stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Cure Truss Offices of S. N. MARSH & CO., No. 2 Vesey St. (Astor House), New York, and S. N. MARSE, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Ciucinnati. OPPOSITE THE HIGH STEEPLE. car Agents for Clement's Patent Artificial Legs. F. E. suire & Co., WHOLESALE DBUGGDSTS, INA. A. INT TVJ EF A C T TU TER, ITN Gº. £Hexists AND PHARMAceutists, CINCINNATI, OHIO. Have constantly on hand a full assortment of s]ex.xºcºexex) ox{U GS ANYO IWY)&xxx.cxxxes, cxxxerºxx.cAx. Axº~A)&Akºus, TEST5, MEDICAL, GLASS WARE, &c., &c., And solicits the patronage of the trade and profession. We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, Made in accordance with the U. S. P. and other recognized authori- ties. FINRL A-ND HEARE CHEMICALS. Of the popular class of preparations known as IE I IDK. I ER, S, We manufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in thern in the quantity named. 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It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMES A. FOSTER, 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cincinnaati, Ohio, or 172 Jef- ferson Avenue, HDetroit, Mich. SAML. P. THOMAS º'A. I. DEA LER IN English, French and Scotch GOOHDs, 2 34 West Fourth Street crwcz.w.wcz Tz. DIVIDED MEDICINES, The Divided Medicine Comy, CINCINNATI, OHIO. 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Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calis with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. For Samples, Price Lists, and Agencies, address EODK 2ess, . Or FRFDERICK KRAUS, Chemist and Druggist, Walnut Hills, Cincinnati, O. MR. FREDERICK KRAUs: CINCINNAT1, February 15, 1871. Dear Sir—The specimens of your “ Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: - SUI, PII: MOP PPI I I....................... % grain in each square. ARSEN: ACID.......................... 1-20 grain in each square. “ CH IN INI .......................] {{ { { { © tº CALOMEL % “ 44 6 & 4 : COPPER ........................}% tº 6 --- REsproTFULLY Youes, E. S. WAYNE, Analytic Chemist. TIEI IEE C T , T N T C . 193 Wol. 2.] S A T U R D A Y, A P R I L 27, 1872. [No. 17. O RIG IN A L A R T I C L ES. —-º-º-º- FIEROUS POI.YPUS OF THIE UTERUS. SRemarks upon a Case presented to the Montgomery County Medical Society. BY J. C. REEve, M. D. dayton, Ohio. GENTLEMEN: . . The specimen presented to you this evening is a fibrous polypus of the uterus, therefore neither very singular in character nor rare in occurrence. Neverthe- Hess, as the subject has never been before this society, and as many points connected with the dise as are of very considerable practical interest and import- ance, I will occupy your time with some remarks which, if they add nothing to the knowledge of the older mem. bers may possibly be of interest to those who have had less experience with the class of diseases to which this belongs. In one respect the specimen merits attention, I allude to its size. Somewhat smaller now, since its immersion in alcohol, it measured when first removed 5% inches in length, in circumference 10 inches, and weighed 17 oz. avordupois. The pedicle measures two inches in its shortest diameter. Since writers speak of these tumors as sometimes reaching “even the size of a child’s head” this must be considered a large one of its kind, much larger than generally met with. . I will read you a brief sketch of the case. Mrs. B.- 41 years of age, a tall and spare woman, of very pale complexion. She has generally enjoyed good health ; has had three living children and two miscarriages; the last confinement twelve years ago; menstruation generally regular but always too free. About three years ago she was taken with flooding, and since then it has occurred as often as every two weeks and has some- times been severe; at times the flow has been so great as to place her in a dangerous condition. It has not occurred for three months except once, four weeks ago When it followed an examination. She has had consid- erable, but not excessive, leucorrhea; has not had offensive discharges, has not suffered severe pain in the pelvic region, nor had expulsive pains like labor pains. Her appetite is excellent. The pulse indicates no febrile disturbance, but it is feeble. There has been difficulty of defecation, and the bladder is disturbed in its func- tions, micturition is frequent, and to accomplish it the Patient is obliged to push something out of the way. thrown in with a syringe. This obstructing body has been called the uterus, by a physician who treated her a year for prolapsus. By Dr. Shuler, under whose care she has more recently been, who has treated her very judiciously for the attacks of hem- orrhage, it was immediately recognized as a fibrous tumor. Since then, however, it has been pro- nounced by another physician to be a cancer. An ex- amination revealed the rounded, smooth and hard end of | this tumor, filling the vagina down to the outlet and extending up beyond reach ; it was slightly movable, and not tender to the touch. Externally, a round, smooth body smaller than this, could be felt just above the pubes, believed to be the fundus of the uterus. A uterine probe, well bent, passed over the body of the tumor and the point could be carried all around it ex- cept at one point where it met with obstruction. An examination by the rectum revealed nothing more and the speculum was not used. The operation for its removal was deferred for a week to allow the supposed time of the next menstrual period to pass. The patient was then placed in Sim's position, and anaesthetised by Dr. Conklin with the mixture of chloroform, alcohol and ether, while Dr. Shuler assisted me. I had determined to first pass my whole band into the vagina and after learning the size of the pedicle and mobility of the tumor, decide upon the other steps of the operation. As I could not, even in this manner, reach the pedicle satisfactorily, I of course selected the ecraseur. A wire rope of fifteen strands was pushed up over the tumor and the staff of the in- strument passed up anteriorly, the screw was tightened and there was every prospect of Špeedy success, but no great progress had been made before the rope gave way. A single strand of annealed wire was now carried around the tumor, pushed high up and tightened as before. The pedicle was not divided before this gave way a second time, the first break having been external and easily remedied. I now determined to attempt delivery of the tumor rather than lose more time in dividing the pedicle, and fixing a strong Mueaux forceps in it found it came down much more readily than before ; with a second forceps opposite, and aided too, by a finger in the rectum, as first advised by Ould for assisting the head of the child to clear the perineum, delivery was effected. The remainder of the pedicle was then divided by the scissors. Sims' speculum was immediately introduced and the vagina Sponged out; there was a pretty free flow of blood and a solution of sub-sulphate of iron was Pledgets of cotton, the first few dipped in the solution, were then introduced and the vagina effectually plugged with dry cotton, no ordinary quantity being required to fill up the enormously dilated canal. After a short time the patient was placed in bed, a hypodermic injection of morphia administered and at the end of a few hours left comfortable. Her convalescence followed without serious disturbance. The pathology of polypi of the uterus is well under- stood, so well that it is surprising what a multiplicity 194 [APR. 27, 1872. T H E CI.I. NI c. of names they have received and how much confusion of terms has resulted. It is not necessary upon this occasion to go into this labyrinth of nomenclature or to attempt an explanation of the classification of different authors. Let it suffice to say that they are all formed by an over-growth of some one of the normal tissues of the uterus, and that, in my humble judgment, the simplest, and therefore the best classification is that which recognizes this fact and is the one adopted by Courty, [Traité Pratique des Maladies de l’Uterus, Paris, 1866], a classification which divides these growths into, 1, vascular; 2, mucous; 3, fibrous; the latter by far the most frequent of all. Either of these tissues may be excessively developed and yet no polypus result; to render this term appropriate the tumor must be con- stricted at its base into a narrower portion or stem. Hence Thomas' definition of polypus, “a tumor covered by mucous membrane and attached to the uterus by a pedicle or stem”; and the statement of Courty that “the existence of a pedicle characterizes the polypus” and is the distinguishing mark which prevents con- founding them with fibrous tumors and other growths “from which they do not fundamentally differ and of which they are often only a consequence or a more ad- vanced degree of development.” The steps by which a fibrous tumor of the uterus, intra-mural at first, becomes by degrees extruded and pediculated are detailed in the text books and I will not occupy your time with them, however interesting this part of the subject may be. The symptoms of the presence of a polypus have been well illustrated in the history of the case before you. Hemmorrhage—either as menorrhagia or metrorrhagia, or both ; leucorrhoea, sometimes pain, or pains such as that to which the term uterine colic is applied; and, if the tumor be large, the difficulties resulting from pressure upon the pelvic organs. Loss of blood at irregular periods and in irregular quantities is, however, the one prominent symptom of polypus and ought always to lead us to suspect its presence. But it should be borne in mind, in regard to this and all other symptoms that their severity bears no relation to the size of the morbid growth. It is well known that very small polypi may cause profuse and exhausting hemorrhages. Courty says, “I have seen them only the size of a pea give rise to very severe uterine pains and hysterical phenomena such as I would never have believed to depend upon their presence, had I not seen them entirely disappear after ablation of the polypus while they had resisted until then the best directed treatment. Scanzoni [Kran- kheiten der Weiblichen Sexual Organe; Wien, 1857] says he has discovered by examination polypi as large as a goose egg or a man's fist and the patients have de- nied, in the most explicit manner, suffering any pain. The presence of these symptoms then should lead to a physical examination. case to-night does no more than to impress upon the junior members of the profession present, the absolute uecessity of this step, it will have done no insignificant And if the prseentation of this. amount of good. The lesson is not perhaps necessary to them on account of want of experience or want of knowledge; but because it is for them particularly difficult to obtain an examination. What is readily accorded to their older brethren is often denied to them or only permitted upon the strongest representations of its necessity. To them, therefore, is the temptation par- ticularly strong to pass these cases over and give them the go-by with some such loose diagnosis as “change of life” or “falling of the womb.” If the unscientific method of this course does not strike you I need only allude to the different effect upon your reputation should a tumor be afterwards found by another practi. tioner in a case where you had followed it, or your better position had you insisted upon an examination and been refused. To assist in obtaining permission to make an examination you may state to your patient that the day is certainly past when any one pretends to treat uterine hemorrhages without it. An examination having been made and a tumor found vou have next to decide upon its eharacter. Cystocele vaginal hernia may be immediately distinguished from fibrous polypus by their totally different consistence and feel. Neither hypertrophy of the neck of the uterus nor pregnancy could certainly be confounded with it. Nor would it seem likely that there could be a mistake about prolapsus. There was, in this case, it is true, but it is only charitable to believe that an examination was not made and that the error arose from that careless mode of procedure already alluded to. Nevertheless, I must call your attention to the fact that Scanzoni (op. cit. p. 214), states that he was once deceived by a pecu- liar separation of the fibres at the lower segment of a uterine polypus which formed an opening so exactly similar to the os uteri that not until he had found the true os higher up and surrounding the pedicle was he undeceived. The rarity, however, of this condition of things may be judged of from the fact that it stands alone, not only in his own, but in all the recorded expe- rience of others so far, he states, as he can discover. It does not seem as if there ought to be any difficulty in distinguishing such a growth as this from Schirrus. It has but two symptoms of the latter disease, the hard- ness and the hemorrhages. The pain of polypus, where there is pain at all, is not so severe or so constant and is of an entirely different character, while the offensive dis- charges of cancer are entirely lacking. In regard to the constitutional symptoms there may be difficulty of dis- tinguishing between them, for the patient in this case presented such an appearance as might easily have been held to be cachectic and certainly excited my suspicion before examination. But the mobility of such a tumor as this, its smoothness, the ready passage of the finger around it in every direction, the absence of any sem- blance of an os, ought certainly to enable one to dis- tinguish it from a disease, the peculiar characteristic of which, is to implicate all neighboring organs, to pay no regard to natural boundary lines, and to run all tissues APR. 27, 1872.] together into a common mass. But although generally the differential diagnosis between polypus and cancer is easily made, and in the individual instance before us there was no excuse for the error, exceptions occasionally present themselves and should be borne in mind. Thus, Sims gives a case, with a diagram, ( Uterine Surgery, p. 73,) in which a hard knobby growth occupied the position of the os and cervix in a woman 48 years of age presenting “almost exactly the cachectic physiognomy of carcinoma” It proved to be a fibrous polypus of mushroom shape, fitting closely over the os and with so short a pedicle as to be scarcely movable. Scanzoni, too, (p. 213) calls attention to a condition of things which may deceive a superficial examiner; the lower segment of a polypus having suppurated and ulcerated, a ragged opening is produced which may bear a very close resemblance to an os broken down and eaten by cancerous ulceration. The detection of the real os higher up would dissipate all the doubt of such a case. * It may serve to indicate to you the progress made in this branch of medicine to state that in the first work upon diseases of women read by me after commencing practice, these tumors were confounded with cancer, and that it is only within this recent period that a differential diagnosis has been cleverly taught and made possible to all of us. A tumor of this kind in the vagina may be but the projecting portion, and but a relatively small portion of a fibrous tumor of the uterus. An interesting case of this kind I have had recently under my care. To the touch exactly similar, because in nature identical, and accompanied by the same symptoms, the error would not be so great except as regards treatment. The recog- nition of a pedicle would be alone necessary to dis- tinguish the two; this is a fact only difficult when the vagina is blocked up by the size of the mass, and to effect it the sound may be used or it may be necessary to introduce the whole hand into the vagina. Inversion of the uterus is the condition presenting very great similarity to a uterine polypus both in its symptoms and its physicial signs, and numerous instances are on record where the error has been made with most disastrous results to the patient, and some, too, where the patient has escaped the perils of an operation. Upon this point of diagnosis the history of the case is of the greatest importance and should always be carefully con- sidered. Inversion is generally an accident to parturition and the symptoms should therefore date from that pro- cess. The discovery and recognition of the body of the uterus is an important step; if the patient be too cor- pulent to permit this to be done through the abdominal walls it may be effected by rectal or combined recto-vesi- cal exploration. Again, upon passing a probe up by the side of the vaginal tumor, it passes in inversion, only to a certain and nearly equable depth all around. By attention to these points the diagnosis an generally be made; mistakes have occurred, however, over and over again, and to men of the highest standing in this depart- T ET H C T , T N T C. cordance with general experience. 195 ment of practice; almost every author gives instances, The want of sensibility of the tumor may, at first thought, seem to be a distinguishing feature of polypus as compared with the inverted uterus, but this symptom is not reliable and its absence is only presumptive. It is a fortunate circumstance for much-suffering wo- men that these growths are very amenable to treatment. Their removal is easily effected and accompanied by very little danger. Probably in few diseases can we give so great and so permanent relief with so little risk, rescuing the patient from frequently-recurring and dan- gerous hemorrhage, and placing her at once in a condi- tion of"comfort and safety. Very few more striking in- stances of improvement in our art can be adduced than has been made in the treatment of uterine polypi. The necessity of their removal and its practicability have long been recognised, but in the mode of effecting it the advance has been made. Formerly, these growths were removed by ligation; a ligature was carried around the pedicle, gradually tightened, and sloughing of the tumor thus occasioned. Now, their immediate removal either by the ecraseur or scissors is the plan followed, and I should not occupy yomr attention with remarks upon this part of the subject if I did not know that the older, more dangerous and abandoned plan is still followed by some in spite of the teachings of all recent authorities. Of course it is the fear of hemorrhage which has caused and causes the use of the ligature, a fear not altogether groundless it is true, for Sims states that he has known fatal hemorrhage to follow removal by the scissors, That, however, was before we had the styptic preparations of iron to rely upon ; with these at hand there need be little fear of serious loss of blood. Yet even without these styptics it is impossible that the mortality should reach that which follows the use of the ligature. Dr. Routh says, [Lettsomnian Lectures 1863] “when it was the common practice to tie a uterine polypus and allow it to slough off, the mortality of the operation was forty per cent,” which is simply enormous! This is in ac- Scanzoni says that he has treated but three cases with the ligature and all had dangerous symptoms while in twenty-eight other operations convalescence was speedy and uninterrupted in every single instance. In these cases he used the ligature only because the pedicle was implanted towards the fundus of the uterus, a circumstance which we now know does not prevent the use of the ecraseur, West's presentation of the dangers of the ligature are perhaps too well known to you to need quotation; he refers to Lee's twenty cases with nine deaths—“a mortality more than double that of the operation of lithotomy, as high as that which occurs in placenta praevia, and higher than the mortality from malignant cholera.” So Langenbeck, McClintock and many others have shown the gravity of the proceeding, and, latest of all, our countryman Sims denounces it as an operation “fraught with great danger” and “not only hazardous but culpable!” Had he lived in this Section, however, he would not have written that 196 [APR. 27, 1872, TIH. H. cI, IISTrc. the day for the use of the ligature had “gone by never to return.” On the other hand, all authorities testify to the slight amount of danger attending excision. To Dupuytren, I believe, is due the credit of first demonstrating this fact; his experience, extending to two hundred cases | with only two instances of severe hemorrhage gave the profession confidence in an operation which is now almost universally adopted, and considered as the only accepted method of treatment. Under certain circumstances, when the pedicſe is very thick, when, as in the case before you, the size of the tumor is such as to prevent access to the pedicle, the mode of excision must be by the ecraseur. I will close with a few words upon this instrument as possibly my experienee may be of some service to you. You will have remarked that the cord or wire of the instrument broke three times during the removal of this tumor, an occurrence I need not say, both unpleasant || and embarrassing. But had this been the only occasion upon which the accident had happened it would be less worthy of remark, but it has occurred to me in every operation but one in which I have used the instrument and in that one the pedicle was not very thick. The instrument I have used is Braxton Hick's wire rope | ecraseur, an instrument which has been very highly praised, and held to be especially adapted to such cases | as these from the greater facility with which a wire or wire rope can be carried to its position as compared with the chain of the ordinary ecraseur. I should be disposed to ſay the blame of my iſlfortunes with it upon the instrument maker had it not been that I obtained mine directly from London, which precludes this view of the case. But whatever may be the explanation I have given you my experience; it is certainly not assuring in regard to this instrument, nor such as would lead one to | reject for it the chain ecraseur. At the same time it should be stated that it is not in accordanee with high authority. Hewitt, for instance, speaks highly of Brax- | ton Hick's ecraseur and especially recommends it for || polypi having a very thick pedicle. There must be | however something faulty in the construction of the instrument, and I believe the cause of the giving way of the wires is to be found in the actite angle at which they are drawn into the staff and over its edges when the tumor is large or the instrument has to be passed $igh up. * - ——º-O-º------— ABSCESS OF THE SPLEEN. BY PHILO. E. Jon E3, Mſ. Tº. Wauseon, Ohio. Nellie ſ—, ±t. 15 months, was brought to me for treatment February 15, 1872. T’arents state she had intermittent fever last fall and fore part of the winter. At present she has slight fewer every afternoon with bilious diarrhoea. She is very anaemic. The spleen is: slightly enlarged. She was ordered quinine, iron and sub. nit. bismuth. - - February 25. By request of parents Dr. Wm. Hyrd, of this place, visited the patient with me. Diarrhoea: has been arrested. She has but very ſittle fever after- noons. Appetite and digestion very much improved. Spleen so much cnlarged as to produce some bulging of the abdominal walls; tenderness to pressure. Treatment.-Quinine, iron, and cod liver oil with unguent. potass iodid. applied to the surface of the tūmor. - • March 15. Condition of generaſ system about the same; tumor increased to nearly the size of an inverted: teacup ; no discoloration of skin, fluctuation perceptible. The quinine, iron and cod liver oil were continued and now warm pouſtices were applied to the tumor. March 22. Tumor one-third larger than at last date; fluctuation still more distinct, me diseoloration of integument. M- Supposing perſtoneal adhesions to have taken place over the abscess, a free incision was made allowing the discharge of over one pint of pus. General and loeak treatment continued. April 8. The child is making a good recovery. —-º-º-º- § C U R V Y - A Report on the Epidemic of Scorbutus in Paris. during the Siege in the Winter of *70-71. Compiled from Various French Anthors. |BY É)r. O. BERGER, (Breslau). Arn, Abstract from Scnmidt’s Jahrbücher, Mar. 12, 1872. wº - During the siege of Paris in the winter of 1870–71. numerous cases of scorbutus occurred in the different hospitals, jails and other public institutions of the besieged city which gave rise to a series of works of more or less value by French authors from which the follow- ing abstracts are made. We commence our report with the work of H. Delpech (Ann. d’Hyg., 2 sér. xxxv, p. 297, Apr., 1871) whose studies were directed principally to a critical explana- tion of the still obscure points in etiology of this dis- €3.Se. - - The author made his first observations in the house of correction, Rue de la Santé whither he had been called to investigate into the causes of the recent out- break of scurvy as an epidemic. He found at first only six patients with pronounced manifestations of scorbutus and these had all been affected for but a short time. * APR. 27, 1872.] TIEH E CIT, IT INTI C. 197 At a later period, up to Feb. 15, '71, the disease had attacked 65 of the inmates whose total number was an average of 250. All patients uniformly exhibited con- siderāble swelling and bluish spongy appearance of the gums, most intense stench from the mouth, hemorrhagic tendencies and cutaneous spots of purpura. In the majority of cases he observed broad, subcutaneous ecchymoses, rheumatoid joint pains, extreme debility, palpitations of the heart, habitual depression and Oedema in various grades. The correction house mentioned is situated in the south-western part of Paris in one of the healthiest regions of the city, in the midst of wide garden rich terrains. The internal construction of the house fulfills the same demands of hygiene. Since the first appearance of the epidemic all the prisoners have been permitted to remain in the open air the entire day. Of 850 German prisoners brought in from the 12-31 January, no single one became affected, while on the other hand those who were brought in since the begin- ning of the war and were subjected to the prison regime furnished a very important contingent of the sick, Some of the patients were brought into the house already attacked with the first symptoms of the disease and others had shortly before suffered from other dis- eases so as to be in condition [as e. g., after mercurial treatment] to offer but little resistance to the real causative agency prevailing in the house. Concering now the etiology of this affection, the author thinks that the depressing psychical causes, empha- sized by different authors as the most essential agent in its production, play really only the role of a predispos- ing cause to which other, entirely different and particu- lar causes must be added to develop the disease. That psyschical causes alone are not sufficient is proven by the fact that no case of scurvy ever showed itself in the house previous to the epidemic. Other alleged causes are extreme bodily exertion on the one hand and lack of eacercise on the other. Neither of these factors were con- cerned in the existing organisation of the house. Nor could over-crowding be brought into consideration as during the time of the seige the number of inhabitants was less than usual. Long continued cold is said to be of special importance for the development of scurvy (Rouppe, Borchardat). Lind, however, (A Treatise on Scurvy, 1752) combats this view and remarks that Sailors are affected just as often in the tropical as in the arctic seas. So too, Leon, a marine physician emphasizes the fact that according to his observations epidemics of Scurvy are not influenced by the variations of the ther- mometer or change of temperature. On the other hand, reliable investigators (Wyatt, John Hall, Scrive, Gerrier) have declared that an excessively high temperature may develop scorbutus. In our epidemic the influence of cold can not enter into consideration as the house was properly warmed from October 12, on. The author illustrates these facts by three cases from which it is evident that the change in nutrition, especially the absence of vegetable food, is the cause of the affection. As to the influence of cold it is annulled in causation by the fact that the German prisoners though they were long exposed to the most intense frost, yet escaped attack. Next to cold, moisture is alleged to be an im- portant cause of scurvy as particularly remarked by Lind, who presented a series of more or less strong argu- ments in proof. In the production of this epidemic, however, moisture could not have participated, as the patients were not at all exposed to its influence. From time immemorial, insufficient nutrition, both quantitative and qualitative, has been cited by most authors as the cause of scurvy. In this consideration the prisoners of the house had much to suffer during the siege. The good diet of the house was forcibly changed when from September 23, on, meats, green vegetables and potatoes were suddenly withdrawn. Since there was no other change in the hygiene of the house than the manner of nutrition, the cause of the epidemic is to be attributed to this agency alone. As to the ques- tion whether it was a simple insufficiency in the quantity of food the author decides from facts observed outside of the house than insufficiency only plays the role of many other depressing agencies, i.e., predisposing, but is able by no means, without the concurrence of other quite special causes (withdrawal of fresh vegetables) to develop the disease. As proof in párticular that scurvy may develop under the most favorable conditions, if there be lack of vegetable food, the author cites the case of a patient affected with rheumatism and scorbutus in marked degree who had had an abundance of fresh horse flesh during the whole winter, having eaten no salt meat Fresh vegetables and sour fruits soon restored him to health. As to the quality of the food, the author is of the view that the alleged injurious influence of salt meats and the abnormal increase of common salt in the blood resulting therefrom, is by no means proven, and he sup- ports this view by the report of a case of scurvy in a lady who had lived in the most favorable circumstances, who had always had fresh meats but who had been denied all vegetable diet since the beginning of the siege. In the prison there can be no question concern- ing the influence of Salt meat because absolutely no meat of this kind had been furnished the inmates. The lack of fresh meat, which also followed in the prison, exercised only a secondary, predisposing influence, and experience teaches that total abstinence from all meats cannot be the cause of scurvy. Whole populations, certain religious sects entirely abstain from flesh diet and yet among these people scurvy is rare or entirely unknown. The different patients in the house received at all times a certain quantity of fresh meat and yet some of them were attacked with scurvy. . It is otherwise, however with the withdrawal of fresh vegetables. Common belief, the instinct of sailors, from time immemorial have attributed scurvy to this cause; . and Scientific facts prove, moreover, that in the absence whatever, but had been entirely deprived of vegetables. 198 [APR. 27, 1872. TIH. H. cI, IISTI c. of every other agency, the absolute suspension of vegetable diet is a sufficient cause of scurvy. The author believes that the withdrawal of vegetable food is the most potent, if not the only essential cause in the development of this disease. An epidemic of scorbutus broke out in the French army before Sebastopol and reached a colossal extent in consequence of the fact that all vegetation in the vicinity of the camp was parched by the increasing heat. Scrive, also, (in his “Relation méd-chir. de la campagne d'Orient,” Paris, 1857) expresses it as his opinion, that the withdrawal of fresh vegetables is the sole causa efficiens of scorbutus. Leon (“Contribution à l'étiologie du scorbut,” Arch. de méd. nav. ix. 1868) is of the same opinion. This author states that of all the ships ordered to Mexico in 1867 to return the troops, only the Castiglione, a vessel abundantly pro- vided with fresh meat, whose crew was subjected to neither cold nor wet, was attacked with scurvy because of the deprivation of vegetable diet, while all the others having had the opportunity of storing in vegetables, were spared. From the moment of landing at the Azores islands where opportunity was afforded the Castiglione to lay in a stock of fresh vegetables all the scurvy patients on board rapidly recovered. Delpech bases his view of the paramount importance of vegetable diet, so far as scurvy is concerned, on a series of cases where it is seen that abstinence from this kind of food is the sole and only cause in its development, and the exhibition of fresh vegetables and sour fruits (oranges, apples, lemons, celery, lettuce, dandelion) was attended with the happiest results. In the hospital “Du Gros Caillou,” from the time that the vegetables began to diminish in the hospital economy to complete absence Hater, the author began to observe in numerous patients, purpura spots, disease of the gums and epistaxis—a clear proof of the influence of the change of nutrition. It was ascertained further, by eommunication, from Dr. de Fornel, marine physician, that the crews of the ves- sels which watched over the shipping interests on the island coasts protected themselves from scurvy only by adding to their daily food the fresh dandelion gathered every morning, the only vegetable that grows in that rough climate. The author then cites from Lind's clas- sical work on scurvy, numerous proofs to the effect that these facts have been known for more than one hundred years. In reference to the treatment of scurvy Delpech ex- hibits in a series of observations, partly his own, partly other physicians,’ during the siege, that the treatment by fresh vegetables and Sour fruits is the treatment proper for the disease. When the disease manifested at the house of correction, the dietetic regimen was changed so as to allow five kilogrammes of red beets in the soup of every one hundred persons. Notwithstanding this change the disease extended itself further and of sixty- five patients, eleven died, more than one-sixth. Of the sixty-five cases two occurred in Oct., nine in Nov., thirty-five in Dec., fourteen in Jan., and five in the first half of Feb. The largest number of deaths thas oceurred in December. These figures correspond to the times when fresh vegetables were allowed or denied respec- tively. The duration of the disease lasted from fifteen to seventy-one days. The conclusion to be drawn from this work is that every where contained in its text that the true cause of 8curvy is the withdrawal of vegetable food. . [To be Continued.] —º-º-º- D Is E As E of T H E G R A Y MIAT r E R or * T H E co R D . Trainsactions of the Vienna Medical Society. Session March 6, 1872. From the Wiener Med. Presse, March 31, 1872. Docent Dr. Rosenthal delivered a lecture on the “Forms of Disease of the Gray Substance of the Spinai Cord.” The gray substance of the cord has hitherto not re- ceived that pathological consideration which its physio- logical dignity merits. It was reserved for the very latest investigations to assist in supplying the deficiencies in our knowledge of this subject and to cast a few illuminating rays over the dark field of spinakpathology. It cannot fail to be interesting then to communicate the most essential of these discoveries of modern med- icine worked out both at home and abroad. As a point of departure is selected the nucleus at the first station of the spinal tract, the gray substance of the glosso-pharyngeal nerve. The Hesion of the cerebral nerves imbedded here figures under the name, paralysis glosso-pharyngo-labialis, more properly it should be de- noted as a paralysis of many nerve nuclei. Dumésnil, Huber, Wedl, Gerhardt, Leyden all referred this affec- tion to atropy of the cerebral nerves or of the medulla. oblongata, atheroma of the basilar arteries and fat cell formations in the spinal cord. Charcot and Joffroy were the first to give an anatomical explanation for the significance of the symptoms as inductively ascertained. They demonstrated progressive atrophy of the cells of the nerve ganglia. This atrophy in the rule—as sections of the atrophied cells of the hypoglossal ganglion showed —reached its maximum in the region of the calamus scriptorius while the vicinity of the pneumogastric ganglion showed the least changes. - By this progressive atropy of the ganglia of the corres- ponding nerves, the closely contiguous centres of articu- lation, phonation, deglutition and respiration become disorganizsd ; lesion of the vagus ganglion arrests the action of the heart. Lesion of the gray substance of the anterior half of the cord exhibits the well known forms of infantile spinal APR. 27, 1872.] TIH. E. cI, IISTI c. 199 paralysis, progressive muscular atrophy and the fatty muscular atrophy, vulgo muscular hypertrophy. In the spinal paralysis of children, Prevost and Vulpian, Charcot, Joffroy and Parot and most recently Reckling- hausen have demonstrated absence and malformation of the anterior horns, with portial loss af nerve cells and atrophy of the anterior roots and the anterior lateral columns. . The speaker, also, had the opportunity of confirming this condition which is in opposition to the view of the French authors, the primary acute atrophy of the cells of the anterior horns. The marked vascularisation of the altered anterior horns, the dilatation and thickening of the vessels, the occurrence of nuclei about the vessels and in the lymph spaces speak rather for an active participation of the vessels in the pathological process whereby the nutrition of the nerve cells is altered and thus is the impulse imparted for secondary exuberations and malforma- tions. - w In progressive muscular atrophy was found by Cruveillier, Valentiner, Leubuscher, and more recently by Bamberger, Grimm, the speaker and others, atrophy of the anterior roots and of the anterior lateral columns. | Degeneration of the gray substance was claimed in these cases by Luys, Gull and L. Clarke but it was re- served for Charcot and Joffroy to demonstrate in two cases chronic atrophy of the nerve cells of the anterior horns, with atrophy of the anterior lateral colums as the true pathogenetic condition of the disease. Only in most recent tim,es have Barth, Müller and Martini exhibited microscopically that cases of fatty muscular atrophy, vulgo muscular hypertrophy likewise depended upon atrophy of the nerve cells of the anterior horns. - As may be seen from the three forms of disease of the gray substance of the cord given, they depend upon a degeneration of the highly important motor and trophic centres of the muscles of the trunk and extremities in the anterior eolumns; the further connecting tracts run into the anterior lateral columns and in the anterior roots. ‘s * Degeneration of the posterior columns may sometimes be combined with a partial disease of the cells of the an- terior horns. Charcot demonstrated an hitherto unpub- lished case of tabes with muscular atrophy of simul- taneous origin in a lecture with most istructive micro- scopic preparations. In this case besides the wedge shaped degeneration of the posterior columns, the rare- faction or partial disappearance of the cells of one anter- ior horn (in comparison with the other) was quite remarkable. , - In diffuse parenchymatous myelitis from pressure (in consequence of vertebral caries), the speaker in connec- tion with Meynert (1869) was able, during life, to refer the analgesia with unaffected sense of touch [Kontakt- gefühle]—as subsequently microscopically demonstrated— to amyloid degeneration of a part of the gray nerve cells of the $pinal cord. Joffe has also remarked a similar condition in a case of analgesia in an insane patient. These are conditions which confirm and support the experimental results of Schiff (analgesia from simple division of the gray substance of the cord). In the Sclerosis of nerve centres which occurs at different parts [herdweise], Schule has observed that the degen- ation extends by preference to the anterior horns, and Joffroy has seen a destruction of the ganglions of the hypoglossal and facial nerves (with symptoms of a glosso- pharyngo-labial paralysis). In contagious diseases also is the gray substance of the cord co-affected. Thus Oertel in his handsome work on diphtheria has described an immense granule infiltration of the gray substance of the cord, partieularly in the anterior horns which were strewn with micro- scopic hemorrhages. It remains yet for further investi- gations to examine more closely into the spinal centres concerned in all the various motor and trophic dis. turbances occuring in life. A thorough appreciation of these facts will tend to illuminate more fully many phenomena hitherto obscure. —-º-o-º- A C A D E M Y O F M E D H C IN E . *** JAS. GRAHAM, MI. D., PREST., L. WoLF, M. D., secry. \ Transactions April 24, IS72. Reported by Tom. O. Edwards, Jr. DR. BARTHOLOW read a report of a case of epileptiform Tic Doloureux of six years duration cured by the hypo- dermic injection of morphia and the iodide of potassium. [A full report of this interesting case will appear in a future CLINIC]. Cerebro-Spinal Meningitis. DR. N. P. DANDRIDGE presented the specimens of the spinal cord and brain of two cases of cerebro-spinal meningitis. One case was admitted to the Hospital in a delirious condition, and soon became comatose; no history could be obtained. The other was a negro boy who said he was 16 years of age, but was thought to be about 18 years old; lais history could not be fully taken but he stated that he had a chill every other day for the last two years, which statement is considered doubtful. On admission, April 2d, his temperature was 101° and remained so for 2 or 3 days, it then fell to 100° and re- mained so until the 12th inst. Upon the supposition that his disease was intermittant fever, he was given quinia. After he was in the Hospital 8 or 10 days his head became very painful and the muscles of his neck became rigid, also much pain was experienced along the spine. On the 12th his temperature rose to 103°. Cerebro- spinal meningitis was now suspected. Dr. Ayers ex- 200 [APR. 27, 1872. T ET. H. C. T., T N T c. amined his eyes and found incoordination in their movements, and from their appearances suspected brain disease. On the 13th his temperature fell to 98°, on the 18th he was paralysed on both sides, the face was paralysed on one side, the tongue was deflected to the paralysed side; his urine was passed in bed; he was un- conscious, and remained so until his death on the 20th. The treatment after the first few days was quinia, after 4 or 5 days he was cupped on the back of the neck and blistered. Calomel and ipecac were given in small doses, latterly iodide of potassium. The man was Sane, conversed well until he was paralysed. Dr. Dandridge said the case was remarkable, 1st, in the insidiousness of the attack; 2nd, in the complete paralysis, which was not usual. He said he was called to see a child about ten days ago, and found its head drawn back, pulse 100, temperature normal, eyes half closed; the child had felt unwell in the evening and vomited, it complained of much pain in the back, and could not lie in the dorsal position, it died in a few days. It was apparently con- scious but could not speak, and had much difficulty in swallowing, it could not protrude its tongue, but made an effort to do so, its bowels were obstinately constipated. Quinia was given, and calomel to move its bowels with- out effect, bromide of potassium was freely given. DR. D.Awson reported a case that he had seen with Dr. Brent; it was a bright child of 6 years. Opis- thotonos was well marked, skin hot, pulse 100 and feeble, it was placed upon quinia and sometimes potass, bromid. or chloral was given to procure sleep and relieve pain. Dr. Brent remained in charge. He was again called in about two weeks ago, found the child worse, the opis- thotonos had continued during his absence, pulse fre- quent; the child had, however, been bright and playful, it was now stupid and had paroxysms of screaming very violent. In a day or two it became paralysed on the right side and died. He saw another case to-day with Dr. Rosenfelt. In this case the pulse was small and feeble, and the child was restless and nervous, screaming out every little while, opisthotonos well marked. It was put upon quinia. DR. CARSON reported four cases of this disease. One of a lady who had been subject to asthma for years. She was 30 years old and had been free from asthma for some time. Previous to this attack which occcurred about five weeks ago, she was delirious, had hallucina- tions of vision, much pain in the head, tenderness along the spine, more in the upper part, she was very wakeful and sensitive to exposure to light; he had regarded these nervous symptoms as an alternative expression of the neurotic element in her asthma, but since the pre- valence of cerebro-spinal meningitis, thinks that there was probably more organic than functional trouble. She was put upon potass. bromid. and iodid. with exter- nal applications to the neck and spine and chloral at night. She recovered in two weeks. Another case was in a child of 7 years old, which he had scen in consultation, with convulsions, opisthtonos well marked, paralysis of right side, intense hyperesthesia of the surface. It has since improved. He saw another case yesterday of a young man 18 years of age, who had been in bed two weeks; he had complained of pain in his head for ten days previously, had been at times de- lirious with obstinate head-ache, constipation and vomit- ing; last night his pulse was 84, temperature 101, surface cool, rigidity, subsultus-tendinum, more hyperesthesia, he was delirious, there was no paralysis, pupils normal, he was very restless; quinia had been given. He is now taking iod. and brom, potass, in large doses with blister to neck. The Doctor with whom he had seen this case had three well marked cases under treatment, one had become deaf, the other cases were still doubtful. DR. GRAHAM said he had seen two cases with Dr. Fishburn last week. One a child of 5 years and the other of 8. They were attacked suddenly while coming from school, became pale and exhausted, and com- plained of pain in the head. The head of one was drawn back, he was called to see them again a few days ago; the head of the other child had just begun to draw back. At no time in either case was there elevation of temperature, there was intense hyperesthésia of the surface, they were very restless, and soon become stupid; when aroused, complained of much pain; they were put upon opium and quinine. In 4 or 5 days both seemed to recover and regained their appetite; he did not see them for some time but they continued to improve; yesterday, however, one of them became paralysed in the right side and died last evening. The other is now worse, and presents an unfavorable aspect. In these cases potass, brom. and chlor. were given but disagreed, Laudanum was substituted and modi- fied some of the symptoms. —º-o-º-- SCIENTIFIC NOTES The Artificial Production of Epilepsy in Guinnea-pigs. BY PROF. C. WESTPHAL. First is given a review of Brown-Séquard's experi- ments, that, by dividing one-half the cord in Guinea- pigs, after some weeks, irritation of the cheek causes epileptiform convulsions. The epileptogenous zone is the side of the face below the eye, the skin on the lower border of the lower jaw, on the anterior border of the shoulder-blade, and also a part of the skin of the neck. In this zone there is a diminution of sensibility. Divis- ion of the sciatic nerve causes the same phenomena; When both sides of the cord or both sciatics are divided, the epileptogenous zones are found on both sides. The author has found the above to be true. He has also found that when he gives a Guinea-pig a blow, or several blows, on the head with a small hammer, holding the APR. 27, 1872.] TIEEI IET: C T , T N T C . 201 head firmly on a support, or when the animal's head is beaten against a hard substance, there follows an attack of convulsions of exactly the same character. The attack occurs immediately, or from a few seconds to a minute after; then the animal jumps up as lively as ever, or it may lie on its side without making any voluntary movement after coming to. Then it walks with its body curved. in a bow shape; there may also be weakness of the anterior legs, lasting a few minutes. If the blows are too strong, death follows from cessation of respiration, the heart continuing to beat some four or five minutes longer. Artificial respiration may restore life. There is then exalted reflex irritability, and the animal, while lying on its side, makes the motion of running. Some times, after a few seconds, the respira- tion returns spontaneously, and sometimes it is only lengthened, and after a while recovers its ordinary condition. - After a few weeks, the animal having meanwhile entirely recovered its activity, upon pinching the epilep- togenous zone of either side, especially the lower surface of the angle of the lower jaw, there occurs an attack perfectly analogous to those produced in animals oper ated upon according to Brown-Séquard’s method. Before the complete establishment of this condition, a pinch on the above-mentioned zone will cause a partial attack, as will also a series of scratching motions applied to the cheek and neck. If the irritation is applied repeatedly, the attacks be- come less and less severe, and, finally, are scarcely to be noticed. - - - The epileptic condition may set in when the blows are so light as not to cause convulsions immediately. Four or five weeks are necessary for the development of the full epileptiform attacks, though the difference in differ- ent animals is very great. The conditions giving rise to epileptic attack continues from six or eight week to six month or more, then gradually subsides and is lost By one female Guinea-pig the epileptic tendency was. transmitted to her young, which could be thrown into an imperfect attack by irritating the epileptogenous 2OI!62, - As to the cause of this condition, it could not be by reflex action of the injured skin or periosteum, for when he removed both and struck the exposed bone, the at- tacks followed in the same manner as in uninjured animals. Autopsies, made immedfately after experi- ments which had succeeded in exciting convulsions, showed a moderate amount of effusion under the skin without injury to the skull; the cerebrum and cerebel- Hum, the crura cerebri, pons, hippocampus major, and ventricles, were without any constant lesion. There were, however, constantly found in the medulla oblon- gata, or the upper cervical portion of the cord, very fine, Small haemorrhages, from the size of a fine point to the size of a pin's-head irregularly scattered through the grey and white substance. Sometimes these lesions were found lower in the cord, even as far as the dorsal region. Usually there was also blood in the sac of the dura-mater spinalis, and more rarely at the base of the brain.—Allg. Med. Cent. Zeit.—Journ. Psycholog. Med., Apr., '72. INFLUENCE OF RHEUMATISM ON THE CHARACTER. Dr. Faure. (Archives Générales, September, 1871). Rheumatism is manifested under such variable forms that we may inquire, on meeting any thing unusual in a patient subject to its attacks, whether rheumatism may not be concerned therein. Why may it not attack the organs of the cerebral functions on which character depends, as well as the heart, etc.? & Cerebral rheumatism has been long recognized, with its attendant febrile and inflammatory phenomena. It is not of that I wish to speak, but rather of cases where it acts on the whole assemblage of mental faculties. It is a change in the individual, which for a time separates him from his normal habit of thought and feeling; they seem as usual, but are themselves aware of a change. A man who is subject to rheumatism will very often tell you, if you ask him—for he has no reason to refer what passes in his mind to the sensations in his arms or legs, elsewhere in his muscular system—that he has moments of despondency without cause, of inquietude, of forlornness, inexplicable to himself. Then he is dis- couraged without cause, and sees every thing in the shade; that which ought scarcely to be the object of a slight care, becomes the cause of a cruel torment, he is without force, his thoughts can be fixed on nothing, all intellectual work is impossible; if he wishes to solve a problem, he soon experiences fatigue and heaviness of his head, which often turn into a violent headache; then his sensations are altered, his affections cease, he is in- different to every thing; that which has the most right or power over his mind, remembrances which are most dear or most painful, have no interest for him. His character has changed. He is conscious of his condition, and can for a few minutes rouse himself out of it. A crisis may follow, his head is congested, he feels quite giddy. Finally, all these symptoms disappear, and his mind recovers its tone and clearness. The attacks vary much with individual disposition. Sometimes the rheumatic attacks are very slight, or are altogether wanting, or the above-mentioned attacks may occur during the interval between the rheumatic attacks. These attacks follow the same causes as true rheumatic attacks, are variable like the latter, and remittent or intermittent. The particulars of the cases of three physicians and several other persons thus affected are given.—Journ, Psycholog. Med., Apr., '72. SPASM OF THE LEVATOR ANI DURING COITION.—The last number of the Archiv. f. Gynaekologie, contains an article by Prof. Hildebrandt on spasm of the levator ani during copulation. It is a form of spasm of sudden oc- " . . º © as º & to * currence which retains the intromitted organ with pain- 202 [APR. 27, 1872, Tº H. H., C T , T N T C . ful force for a few minutes until relaxation as suddenly takes place. The author details three cases in somewhat graphic description, referring at the close to the little mention made of the affection in the various works of gynaecology. This spasm depends upon no special abnormity of the generative organs simply upon an extreme excitability, being present generally in individuals of erotic tempera- ment. Scanzoni is of the opinion that the constrictor cunni is the muscle affected. The author considers this muscle too feeble to exert such power, acknowledging at the same time that the spasm of the constrictor may prove an obstacle to intromission as occursin vaginismus. The obstacle in these cases, however, is not alone due to the constrictor, but also to the distended glands of Bartholine, which, as Luschka has shown, are pressed against each other during erethism. In explanation of the penis captivus condition, another group of muscles must be sought for, a group which is stronger and deeper in the pelvic cavity than the constrictor. The only muscle which could act in this way, as the author exhibits from anatomical considerations, is the levator ani and what lends support to this view is the resem- blance which cases of tetanus of this muscle bear to this condition. In all these cases the speculum is retained after introduction by forcible contraction. Vaginismus with contraction at the orifice is then due to spasm of the constrictor muscle but vaginismus of deeper seat is due to spasm of the levator ani. The treatment of internal does not differ from that of external vaginismus. Painful surfaces, abrasions, ulcers, enlarged and inflamed carnuculae are to be subjected to local treatment. The general condition is to be improved and the influence of pscychical impressions is not to be forgotten. THE FORCE OF UTERINE CONTRACTION.—The ex- treme force of uterine contraction produces a pressure of 3,402 pounds per square inch, which is equivalent to a pressure of 54,106 pounds acting upon a circle of nine and a half inches in diameter, which is assumed as the average area of the pelvic canal. The maximum force used to expel the foetus, by both uterine and abdominal muscles combined, is estimated by Soulin, by forceps experiments made on a dead body, at 110.23 pounds, a result as regarded by Dr. Duncan as too large. Dr. Duncan considers 80 pounds as the maximum force ever employed in difficult cases. This would correspond with a hydrostatical pressure inside the uterus of 5,05 pounds per square inch, which is greater than the uterine muscles, unaided are capable of producing.—Dublin Quarterly Journal Medical Sciences. - —sº- e -º---— M[E])}{CALL NEWS HIGH SCIENCE.-Along side of the double decompo- sition formulas in chemistry, the mathematics which have struggled in among the flaps in surgery and the trigonometrical synclitism of the foetal head in obstet- rics is to be ranged now a contribution from ophthal- mology, the optics of art. º Mr. Liebreich's lecture at the Royal Institution on Triday (March 8th) was a great success. It attracted a very brilliant audience, numbering the most eminent artists and physicists of the metropolis, and a crowded assemblage of the cultivated classes, who find in the Friday evening meetings of the Royal Institution one of the most agreeable of intellectual relaxations and the most instructive of mental dissipations. He shöwed very conclusively as to Turner, that subsequently to 1830 the great artist suffered from a diffused cloudiness of the lens, afterwards passing into defined opacity, which at first altered for him the face of nature, and subsequently that of his pictures, which were finally de- faced by vertical streakiness, due to irregular vertical diffusion of light. Another kind of defect, which he illustrated by examples, was astigmatism, which became more serious as the accommodation of the eye suffered from advancing years, producing then a vertical en- largement of the objects painted from a distance, and a horizontal enlargement of the lines of the picture, which ended in palpable distortion. In the case of Mulready, he showed yet another kind of optical defect occuring with age, an increasing yellowness of the lens, leading to ex- cess of purple tints in his pictures. He pointed out that such defects as those of Turner's sight might be partially corrected by stenopoeic glasses; the astigmatic errors by cylindrical lenses; and, to some extent, the discoloration of the lens last described by appropriate blue glasses. As may be readily understood these sermons on the physical Sciences, threatening, as they do, the dem- olition of the altars to the unknown gods awaken a most intense feeling among the votaries of art. - A NEW EDUCATIONAL FEATURE FOR WASHINGTON. —Dr. Joseph M. Toner of Washington city has organ- ized a series of lectures “The Toner Lectures” to be delivered in Washington city on the plan of the popular scientific lectures of Great Britain. The Surg, Gems. U. S. A. and U. S. N. and the Prest. of the Med. Soc. of Columbia are made trustees of the funds donated for the necessary expenditure by the following indenture legally signed and sealed. * Whereas the said party of the first part, believing that the advancement of science—that is, a knowledge of the laws of nature in any part of her domain, and particularly such discoveries as contribute to the advancement of medicine—tend to ameliorate the condition of mankind, hath determined to convey and transfer to the said parties of the second part, and their successors forever, in their several official positions as aforesaid, the herein- after described real and personal property, amounting in value to about $3,000, 90 per cent. of the interest of which is to be applied for at least two annual memoirs or essays by different individuals, and as the fund in- creases, as many more as the interest of the trust and revenue will in the judgment of the trustees justify, relative to some branch of medical science, to be read at the city of Washington at such time and place as the said parties of the second part and their successors as trustees may designate, under the name of “The Toner Lectures;” each of these memoirs or lectures to contain some new truth fully established by experiment or ob- APR. 27, 1872.] TIEEE THE CIT, IT INT I. C. 203 servation, and no such memoir or lecture to be given to | the world under the name of “The Toner Lectures” without having first been critically examined and ap- proved by competent persons selected by said trustees for that purpose. - SALARIES OF GERMAN PROFESSORS.—The Mercure de Sonable announces that Gusserow, professor of obstet- rics at Zurich accepts the same chair at Strasbourg with a salary of 15,000 francs. The salaries of the German professors consist of two elements, the one furnished by the university or the state constituting the fixed salary, the other arises from the proportionate division of the fees of the students in attendance. This last sum in certain cases is very large forming a revenue, at times, of more than 25,000 francs per year. It is a recompense for their talent, labor and zeal in instruction.—Paris Med. Gaz. - AMOUR DE LA PATRIE.-The society of physicians of the hospitals of Paris decided in the session of Feb. 23, to take from the treasury the sum of ten thousand francs for the liberation of the land. This was to be indepen- dent of individual contributions. THE STRASBOURG SCHOOL-M. Schimper, the celebrated botanist and palaeontologist, is the only one of the old professors in the French University of Stras- burg who has consented to hold his post under the German rule. M. Schimper is a Frenchman by birth and descent, and had been offered a superior position elsewhere by the French Government. THE FIRST MEDICAL Journ ALIST.-The Medical and Surgical Reporter of March 23, in an editorial with this heading, assigns the honor of being the first medical journalist to Dr. Nicolas de Blegny, who edited the 200iacus Medico-Gallicus from 1680, when it was started, until 1684. Born in a humble station in life, Dr. de Blegny does not seem to have had the advantages of a | learned education: he, however, was possessed of un- usual energy, and at the early age of twenty-five was appointed Surgeon to the Queen. Five years after- wards he became Surgeon-in-Ordinary to the Duke of Orleans, and, four years later, 1687,-Physician to the King, Louis XIV. During these years he was busily engaged in writing and lecturing on various medical topics. None of his works, it is said, indicate much ability; and they are known only through the criticisms of his enemies. The comments of the journal upon Some medical books embittered their authors, who succeeded in procuring its prohibition in 1684. It was then transferred to a Dr. Niort, a French physician prac- tising in Amsterdam, who determined to render it less medical and more literary. With this object he named it Mercure Galant. - The enemies of De Blegny were not satisfied with causing the suppression of his journal, but continued their persecutions until they procured his imprisonment in the castle of Antwerp, where he remained seven years. He spent the rest of his days at Avignon, dying in 1722, at the age of seventy.—Phil. Times, Apr. 15, '72. of restoration of the function of the motor nerves, DEATH OF PROFESSOR: JACKSON.—Samuel Jackson, M. D., Emeritus Professor of the Institutes of Medicine in the University of Pennsylvania, died at his residence in Philadelphia, aged 85 years. DEATH OF PROFESSOR DICKSON.—William Henry Dickson, M. D., Professor of the Theory and Practice of Medicine in the Jefferson Medical College of Philadel- phia, died at his residence in Philadelphia on Sunday, March 31. –-º-º-º- CORRESPONIDENCE. OHIHO STATE MEDICAL SOCIETY. To the Committees on Special Reports, It is the earnest wish of the officers of the Ohio State Medical Society that you make a report on the subject assigned you at the next meeting of the Society. And that you have your paper completed—ready to leave with the Secretary immediatsly after having been read to the Society. The Publication Committee has heretofore experienced great difficulty and been delayed not a little in its work of getting out the Transactions, by members with-hold- ing papers from the Committe, to rewrite them, after their having been read to the society. The object of this note is to obviate that difficulty in the future. J. HADLOCK, M. D. Asst. Secretary, O. S. M. S. —-º-o-º--- CL FINICAL MEMRO RAN IDA. AN IMPORTANT SYMPTOM IN TRAUMATIC PARAL- YSEs. By Dr. Fr. Bärwinkel (Leipsic).-The author believes, and his belief is based upon several observa- tions, that he has found a certain sign of differentation between total solution of continuity of mixed nerve trunks and their simple injury ſquetschung, compression] in high degree, in the different reaction to pressure below the point of injury. If sensation at the periphery re- main, it is a sign that the connection of the sensi- tive nerves with the centre still persists, the motor fibres, therefore, running in the same nerve trunk are not sep- arated. Should this reaction to pressure be absent, a solution of continuity is still not a necessary conclusion, as experience has shown, and especially is this true if reflex symptoms still remain in the nerves concerned. In the first case the prognosis of restitution of sensi- tive conduction is favorable. There is a probability also On the other hand the prognosis is unfavorable in cases in which peripheric reaction is absent while reflex mani- festations still remain. Of course what has been said avails only during the 204 [APR. 27, 1872. TIEH THE CIT I I IN T C . first months after the injury when reproduction of the injured fibres can not have occurred.—Arch. d. Heilk. acii. 4–5. p. 336.-Schmidt’s Jahrb., Mar. 12, 272. TREATMENT OF TETANUs AMONG THE CHINESE.- This mode of treatment of tetanus has been seen by English physicians in China and India to be successful: the patient smokes in a pipe a mixture of from twenty to twenty-five centigrammes of crude opium and tea or rose-leaves, which are worked up with a small quantity of molasses. When smoking, he must inspire as deeply as possible, and continue this operation until the nar- cotic influenee is noticed. This continues then, as a rule, three or four hours. The smoking is repeated as soon as the tetanic symptoms reappear. In the mean time, as much nourishment as possible is given. In using opium thus, it must be remembered that its nar- cotic effect is somewhat neutralized by tobacco.— Psychol. Journ., Apr., '72. PHYSIOLOGICAL AND THERAPEUTICAL EFFECTS OF THE ANTI-DESTRUCTIVE AGENTS, Alcohol, Coffee, Tea, Cacao, Maté, etc., Bourdeaux prize essay by Dr. Angel Marvaud.—The conclusions are first, that alcohol is a stimulant to the nervous system ; second, that it is an aliment which retards the retrograde metamorphosis [anti-déperditeur). Coffee and tea have the same properties and further furnish a certain quantity of nitrogen to the organism. This is ordinarily, however, not their most important role. - Marvaud experimented on himself as to the effects of coffee, tea, maté and cacao on the nervous system. These substances were ingested in cold infusions. Coffee pro- duces a desire for active life stimulating the exercise of the intellectual faculties, while tea induces a taste for a contemplative and quiet life. Maté, which contains the same alcoloid as the preceding, cafeine or theine, has an action analogous to tea but more pronounced, something like the intoxication of the lively wines. Cacao finally with its alcaloid cocaine is a convulsive substance imparting a desire to walk or run, inducing even tremulousness in the extremities. It is an agent causative of muscular activity. The action of these substances on the circulation was studied in several young and healthy individuals, and is illustrated in the essay by a number of sphygmographic oscillations. Coffee and cacao on one hand and tea and maté on the other act entirely differently on the circu- | lation and the pulse. The first of these drinks diminish the amplitude of the oscillations, the others augment them to the degree of alcohol. From the characters of the traces, Marvaud makes the following deductions: “Coffee and cacao increase the arterial tension; tea and maté diminish them.” The author believes with reason that these conclusions are of great importance, though they are not by any means entirely new. Coffeine has already entered into the therapy of cardiac maladies (8ée Jacond, Traité de Pathologie Interne: Dosond and Huchard, Des Complications Cardiaques dans la Variole, etc.). Like digitalis, caffeine, also, in therapeutic doses immediately increases the arterial and diminishes the venous tension whence follow abatement of respiratory frequency, of the hemopoietic functions, reduction of temperature, diminution of the cutaneous and increase of the urinary Secretions, etc. ~ *- The conclusions are thus, that these substances are aliments favorable to vigil and to intellectual and mus- cular activity.—Gaz Med. de Paris, Mar. 9, '72. BROMIDE OF POTASSIUM IN EPILEPsy.—M. Legrand du Saulle gives a resume of the use of bromide of potas- sium in 207 cases of epilepsy, including the advantages and inconveniences of this method with its conditions of success, concluding as follows: En résumé, the bromide of potassium may completely and absolutely suspend all the phenomena of epilepsy: but it is indis- pensable that this medication be rigorously prescribed, followed and watched for several years.-Gaz. des Hop., Feb. 22, '72. BENZINE IN WHOOPING CouGH.—The author, Dr. Rottari, ends his paper with the following conclusions. 1. Asoiration of the gases developed in the depuration of coal gas has a certain influence in the cure of whoop- ing-cough without complications. 2. Very probably this beneficial influence is due to the benzine produced in the distillation of coal. 3. This remedy may be employed with the greatest ease, in the house of the patient and without any danger, if its quantity be varied according to the intensity of the disease. - - 4. Benzine internally administered is at present the best remedy for whooping cough. It may be given in doses of 10-20 drops with mucilage or syrup either alone or accompanied also by aspiration of the same substance prepared in the patients room.—Lo Sperimentale—Gaz. Méd. de Paris, Mar. 2, '72. RE-IMPLANTATION OF TEETH.-At a recent meeting of the Odontological Society, Mr. Steele called the Society’s attention to this subject, and stated that he recently had a tooth of his own extracted with great care. The tooth was in an exquisitely sensitive condi- tion from the exposure of the pulp, and gave pain on the least change of temperature. It was taken out un- der the influence of nitrous oxide gas, the dental canal was cleansed; and caries removed from the crown. It was stopped in the usual way, and the tooth at once replaced in the socket. The operation lasted about half an hour.—Brit. Med. Journ., Mar. 9, '72. IH [OM IE NEWS. THE number of cases of cerebro-spinal meningitis re- ported at the last meeting of the Academy indicate an extent sufficient for consideration as a prevailing disease. The next CLINIC therefore will be a CEREBRO- SPINAL MENINGITIS NUMBER. It is earnestly hoped that all gentlemen who have had any experience in the treatment of this affection will report it in the Academy on Monday evening; a full abstract of the proceedings, so far as relates to this subject, will take the place of original matter. List ºf Pharmaceutical Preparations, MANUFACTURED BY Jø/ZW WyżZVZ & Bºozºº, FRILADELPHIA. —-º- ELIX. PHOS. IRON, QUININE AND STRYCHNIA, - ELIXIR OF GENTIAN FERRATED, ELIXIR WALERIANATE OF AMMONIA, . ." (Goddardi's Formula,) ELIXIR VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, Iron, with RPhosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Iron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK. w ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Coimposed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER WINE OF IRON, Citrate of Iron and Peruvian Bark, . FERRATED CORDIAL ELIXIR, ELIXIR CALISAYA BARK, WINE AND BISMUTH, ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, - TASTELESS COD LIVER OIL, TASTELESS CODLIVER OIL. FERRATED, BEEF, IRON AND WINE. Extract of Beef, Citrate of Iron and sherry wine, ELIXIRVALERIANATE OF STRYCHNIA, WINE OF PEPSIN SYRUP SUPERPHOSPHATE OF IRON. 9 - . ELIXIR OF BISMUTH, COMP. FLUIDEXT. BUCHU AND PAREIRA BRAVA. stſ PPO's ITOR MEs. Rectum, Vaginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great eare, and of every variety of combination. Lists sent on application. SPONGE TENTS.—For the Urethra, of every size and style, made of finest quality of sponge. J||NF||RTS, Carriage Manufacturer, Nos. 9 and 11 East Sixth Street, bet. Main & Sycamore. I MAKE NOTHING BUT Jº Z/º,S 7" CZ.Z.S.S. W’0 ſº M'. Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of LIGHT FAMILY CAFRIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive, variety of light elegant designs of different cost and finish. In vehicles especially PHYSECHANS’ USE. The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. The superiority of my light gentlemen's . buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price lists furnished on application. References to Dr. W. W. Dawson and all the leading Physicians in the city and heighborhood. wº 77 WILSON BRO's. S HIRT S Made to order of N. Y. M. Muslin and 2300 HIEAVY Linen, per dozen - - - $26 00 Wamsutta Muslin and 2100 HEAVY Lin- en, per dozen - - - - - - - - 33.00 Wamsutta Muslin and 1900 Linen, per doz. 30.00 Lonsdale Muslin and 1700 Linen, per doz. 27.0) First three qualities have ALL LIN EN Cuffs and Neckbands. At above prices Cuffs are attached. Same quality of our own manufac- ture, ready-made, $3 per dozen less. Perfect satisfaction given or money cheerfully refunded. Also import and Manufacture Men’s Furnish- ing Goods. ' Pike's Opera-House, Fourth Street, Cincinnati; 931 Wabash Avenue, and 88 West Washington Street, Chicago. CAMARGO MANUFACTURING COMPANY, MANUFACTURERS AND IMPORTERs of AND Window Shades, 67 Wasr Fovazz Sragºr, CINCINNXTI, O. B. H. BRENEMAN, Proprietor, wanTED–Aarºn r=. School Teachers, Students AND OTHERS, Can find light and healthful employment for the Summer, by engaging in the sale of our valuable and very popular works. One lady teacher just commencing work for us, reports net profits for last week at ForTY DoILARs—many others doing equally well, Large commissions or liberal salary as preferred. For particulars, address NETTLETON & CO., 161 Elm Street, CINCINNATI, OHIO. P. S.—We will make “special, TERMs” to medical stu- dents, who are “working their own way through college.” BASCOM & CARPENTER, Stationers, Printers Blank Book Manufacturers, 136 VINE sº IIREET, SYWASYYYYYYp E. De ALBIRO & BIRO. IMPoitters AND MANUFACTURERS or FOREIGN and DOMESTIC WOODS In Veneers, Boards and Plank, Kºi...Mºiſailºimº The only house in the Western country that saws Spanish and Mexi- can Cedar for Cigar-Box Makers: We import our own wood direct, and can sell at prices to compete with any and everybody. Also saw and keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. Office and Warerooms, 136 and 138 West Second Street, Veneer Mill, 501, 509, 5ii, 513 & 515 W. Sixth St., CINCINNAT1. coPI Ivº R. CIL o I O R LEs s AN ID PA. LATA H LE. In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERs & BARTLETT, of Portsmouth, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. - - Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachilic Affections, in Chronic Rheumatism, &c. - The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains ; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. - The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. * tº --º :::::::::::::::=#EEE ...” #==jäiſſipº ºftii, g==#| †† |##| # ###### i ſº == jº |Hºliº |l. | Jºž;#;. |º]||iſ §§ *: # } - Sºś |º § §§§ #|####### āşşāś. #|º || ||#### ſº #|####, § 3. * ſº - ºº: ººt", ºr--> - - 323 tº: º # É= * 3: *- : . | i. lillºS ºfflº • * ºft ºf º? --> ºšíž º % ºzzº % %: !". ºſº º % wº. Lºſºft #x3%ft:% %: -> §º º ººziº, %3: - ×% º 2:54% z- * * É%ſº >º - §3%% £º Šºššº § %32.23 & ºs 2 Sºsº.º.º.º.º.º. Z. F. : - - *~ §§ºž =#: Sº ſº %2--" §s:===Sºsº =3%%)4 GooD sa MARITAN HOSPITAL. The GOOD SAMARITAN HOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner of Sixth and Lock streets. pointments of a First-class Hospital. Porticoes, halls and abundant windows secure that full It is handsomely furnished throughout, and is provided with all the necessary ap- with commanding views, surround the whole house, and wide and free ventilation which is so essential to health and comfort. Service is furnished by the Under the Superintendence of the well- have sacrificed their lives to such purpose know how to afford. The regular Medical Attendance of the house is supplied by the Faculty of the Med Professor presiding over his own especial department. SISTERS OF CHARITY, known SISTER ANTHONY, with that care and attention which only they who ical College of Ohio, each Patients may, however, select from the regular profession of the city any physician of their choice. The GOOD SAMARITAN HOSPITAL presents extra inducements to Invalids throughout the State as a safe and quiet asylum in any case of protracted illness, or in c ases, more particularly, requiring Surgical Operation, where ... some stay is necessary in after treatment. Rooms vary in price, general terms, service. according to the character of appointments necessary and service required, ranging, in between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand ot w gºy" Address, 3. SISTEF, ANTHONY, FHospital of the Good Samaritan, Corner of Siacth and Lock Sts., Cincinnati. Ohio. |-d-- ºSºft-S ºs º 2Sººº. ... ex: 3. Lº ; w * - , -º- ºr T Lif *23 - º-º'-- i t ti | Iri- HI}}{ j } | !, § {|| iº. |||ſiº CINCINNATI. ~~~~ H' A C U L T Y - J A M E S G R A H A M , M. D., D E A N , Professor of the Theory and I’ractice of Medicine and Clinical Medicine. ROBERTS BARTHOLOW, M. D., W. W. DAWSON, M.D., Professor of Materia Medica and Therapeutics. Professor of Principles and Practice of Surgery and Clinical Surgery W. H. GOBRECHT, M.D., C. D. PALMER, M.D., Professor of Anatomy. Professor of Medical and Surgical Diseases of Women. P. S. CONNER, M.D., T. A. REAMY, M.D., Professor of Surgical Anatomy. Professor of Obstetrics and Diseases of Children. JAMES T. WHITTAKER, M.D., JOHN L. CLEVELAND, M.D., Professor of Physiology. e Demonstrator of Anatomy. SAMUEL NICKLES, M.D., º CHARLES KEARNS, M. D., . Professor of Physics and Medical Chemistry Assistant to the Chair of Surgery WV. W. SEELY, M. D., Professor of Diseases of the Eye and HDar, and Secretary of the Faculty *- T. Louis Brown, M. D., Prosecutor of Anatomy. E. NoPI.E, Janitor, College Building, Sixth St., bet. Vine and Race, —- *-*- Printed and Published by Noh R19 & M URRY, Medical College of Ohio Building, Cincinnati. E LINIC. PUBLISHED EVERY SATURDAY. witHM S–$2.00 a Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editor: .º. . . All Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer. Vol. 2. M A Y 4, 1872, No. 18. JAS. T. WFHITTAKER, M. D. No. 101 West Ninth Street, Cincinnati. -A-SSOCIALTE, IEEDITOER.S. W. W. DAwson, M. D. THAD. A. REAMY, M. D. P. S. ConneR, M. D. C. D. PALMER, M. D. W. W. SEELY, M. D. SAMUEL. NICKLEs, M. D. CHAs. KEARNs, M. D. JNo. L. CLEvKLAND, M. D. RobHRTs BARTHorow, M. D. Editor. C IN C IN N A TI, colá. Fºr te Co- Fashionable Hatters, IMPORTERS AND MANUFACTURERS OF Sº W. W. SEELY, M. D., - - - - º º TREASUREE, - No. 118 West Seventh Street, Cincinnati. . r x CLU B R AT Es. 92 WEST FOURTH ST. +copiº one widºw'....…~~~~~ *}} - Opposite Post Office, 6 < ' ' ' ' ' .... 10.0 12 & & “. ...... 18.00 CINCININATI. z - saw-special Inducements to Medical Men. o o y T E N T S. ſº tº-º-º-º-º-º-º- ... •- - Page. A CEREBR.o-SPINAL MENINGITIs NUMBER. N. -- - - - ſmºs aſ N. ºr nº The History of Cerebro-Spinal Meningitis... • * * * * * * * * * * * * * * * * * * g ee e s ∈ e º e º 'º e .....205 Rºriºſa Ni ACA DEMY OF MIE DICRINE SIGNER S ANPº l Transactions April 29, 272. * * º-ºº: Ty S. Cerebro-Spinal Meningitis—Reports of Čases by Drs. --- ENGRAVE RSoNWOOD ;" Brown, Muscroft, Orr, Reamy, Carson. Remarks by Drs. issºl. 3 2 WEST FO UR7. H. ST sº º: Gobrecht, Comegys, Graham. History by Dr. Whittaker......207-209 - ºc INGINNATI. of iro. * TRANSIATIONs — w ~ : - A General Survey of the Disease by Prof. Hirsch 209 - - * -ºr wº The Pathology of the Disease by Prof. Klebs 211| General Conclusions by Dr. Meissner - 213|J. TAFT, W. TAFT. M IELDIGA. I. NEWS- Editor Dental Register . Cerebro-Spinal Meningitis in New York, Buffalo and Brooklyn........ 214 - CORRESPONIDENCE J | & W T AFT fetter from Dr. Darnaji. Spotted Fever in Iowa........................... 214 y C LINICAL, M I EMIORAN DA The Temperature of Cerebro-Spinal Meningitis—Treatment by Qui- nine and Opium—By Morphia Hypodermically—By Phy- sostigma Venemosa—Recommendations of the Amer. Med. Association - * * g e is a s a s º e s is e is a tº 4 * * * * * * * * * * * * * * * * * * * e º s is sº a º is e º se tº e s ∈ n. * * * * * * * * * * * e º s sº e < College Announcement , THE CLINIC of to-day contains all the available in- formation of recent date upon the subject of cerebro- spinal meningitis, which is now present in our city, though hardly as yet, at least, in the proportions of an epidemic. - *. As will be seen, liberal use has been made of Meiss- ner's almost exhaustive collation of its medical literature, 214-21C IDENTISTs 17 WEST FOURTH STREET, CINCINNATI, O. in that vast storehouse of medical knowledge, Schmidt's § 6 Jahrbücher der Gesammten Medicin. . A careful perusal of the few facts established and the many theories propounded leaves us, still, it must be Confessed, in profound ignorance as to its nature, doubt as to its course and perplexity as to its treatment. Cerebro-spinal meningitis remains, in truth, as in- scrutable in its origin as it is lawless and capricious in its development and signs. Lastly, it is so little govern- able by treatment as to show, according to Hirsch, an average, from all epidemics recorded, of 37 per cent. mortality under whatever method of treatment pursued. A Monthly Journal, CONTAINING 48 PAGES, Devoted to the Interests of the Dental Profession, —-mº —-r Wm. Wilson McGrew, wo. 27 mºsr Fovern scºrer, PIKE'S OFEFA House building, - Importer and Dealer Diamond and Gold Jewelry, Watches for Ladies and Gentlemen, Sterling Silver Tableware, Bronzes, Antique and Modern; Marble and Bronze Clocks, .* Marble statuary, GENER ALLY. 4. iMº "lººse: JAMES FOSTER, JR., & CO. Instrument Makers and Practical Opticians, Beg leave to return thanks for the patronage extended to them through § im - - : * - §:= \ a long series of years (having been established since 1836), and in the reorganization of their firm will endeavor to merit a continuation of the same. Wé wish it understood by the Profession and the Public generally that our invariable rule is, to make or import none but the best in- Struments. Lenses, Spectacles, and the best models procurable, with pains- taking skill to adjust them to all conditions of sight, at our house. Special attention paid to orders for Fine Microscopic Objects and Microscopie Apparatus, Magnifiers and great variety. meters, Hygrometers, Urinometers and Baian Gauges, of the most approved constraction always on hand. All orders promptly and accurately filled. . JAS. FOSTER, JR. deali - F. S. SHACKLEFORD, } *** JAs. FostFR, JR. & Co. S. W. Cor. Fifth & Race Sts., Cincinnati, 0. TXTER, S-INT. TML. ALTER,STEI’S 2) TRUSSES. No. 758 BROADwAY, NEw York HAVE been in the habit of applying and recommending the Truss manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined." LEWIS A. SAYRE, M. D. Surgeon, Bellevue Hospital. Readers in Ø • *- º º sº ºr ºf r: ſº º ſº yº SS &Sº sº From Prof. Willard Parker to S. D. Townsend, M. D., Surgeon to the Massachusetts General Hospital. BEG leave to state for the benefit of all concerned, that I have known Dr. S. N. Marsh the last fifteen years. * * I am in the coustant habit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with any of the risks to the patient that exist in many of the plans suggested and attempted to be carried into execution. I have confidence in Dr. Marsh as a gentleman of honor and integrity, and as such recommend him to the members of the medi- cal profession generally. WILLARD PARKEB, M. D. Professor of Sürgery, New York City • *-* Dr. S. N. Marsh's Patent Radical Cure Truss and all other kinds of Trusses, Shoulder Braces, Supporters, Elastic Stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Qure Truss Offices of S. N. MARSH & CO., No. 2 Wesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. OPPOSITE THE HIGH STER PLE, * Agents for Clement's Patent Artificial Legs. - !. Those in want of any of the acknowledged good aids of vision to imperfect eyes, will always find the best and largest stock of Iedical Batteries, Barometers, Thermo- F. E. SUIRE. E. S. WAYNE Suire & Co., WHOLESALE DBUGGDSTS, M. A. N. U E A CT Uſ ER, IIST G. £Hemists AND PHARM aceutists, CINCINNATI, OHIO. Have constantly on hand a full assortment of sex-ecºcero oscos Aso wreoxckwes, ckxxerwſkcAX, AppAyº A*US, TEs.T.s, MEDICAL, GLASS WARE, &c., &c., And solicits the patronage of the trade and profession. we would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, Made in accordance with the U. S. P. and other recognized authori- ties. FINIHE AN ID ERAEHC CHEMICA LS, Of the popular class of preparations known as H. T. IIXIII-R, S, We manufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. Bitter Wine of Iron, An excellent Chalybeate and tonic, Wine of Iron, &c. AGENTS FOR BULLOCK & CRENSHAW'S Sugar-coated Pills and Granules. Price Lists of preparations and of Sugar-coated Pills sent by Mail upon application. The long standing and well and widely known repu- tation of our house we offer as a guarantee for the reliability of our preparation, and the quality of the goods sold by us generally. WILson BRD's. . war"TED–ACENTs. S HIRTS Made to order of N. Y. M. Muslin and 2300 HEAVY Linen, per dozen w $36 00 Wamsutta Muslim and 2100 HEAVY Lin- en, per dozen 33.00 Wamsutta Muslin and 1900 Linen, per doz. 30.00 Lonsdale Muslin and 1700 Linen, per doz. 27.00 First three qualities have ALL LINEN Cuffs and Neckbands. At above prices Cuffs are attached. Same quality of our own manufac- ture, ready-made, $3 per dozen less. Perfect satisfaction given or money cheerfully refunded. Also import and Manufacture Men’s Furnish- ing Goods. Pike's Opera-House, Fourth Street, Cincinnati; 931 Wabash Avenue, and 88 West Washington Street, Chicago. sº º a af CAMARGO MANUFACTURING COMPANY, MANUFACTURERS AND IMPORTERS OF AND Window Shades, 67 Wasz Kotºzºr Szºzz, CINCINNXT, O, H, H, BRENEMAN, Proprietor, School Teachers, Students AND OTHERS, Can find light and healthful employment for the Summer, by engaging in the sale of our valuable and very popular works. One lady teacher just commencing work for us, reports her net profits for last week at Forry Doſſa RS-many others doing equally well, Large commissions or liberal salary as preferred. For particulars, address NETTLETON & CO., 161 Elm Street, CINCINNAT1, OHIO: P. S.—We will make “specIAL TERMs” to medical stu- dents, who are “working their own way through college.” BASCOM & CARRENTER, -A Nº- Printers Blank BOOk Manufacturers, 136 VINE sº IREET, s\\\\\\\s E. D. ALBRO & BRO. IMPORTERS AND MANUFACTURERS OF FOREIGN and DONESTIC woods In Veneers, Boards and Plank, | frºnt-Maºri','l'-Biliń'amilit-Bitri'Wii, The only house in the Western country that saws Spanish and Mexi; can Cedar for Cigar-Box Makers. We import our own wood direct, and can sell at prices to compete with any and everybody. Also saw and keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. Office and Warerooms, 136 and 438 West Second Street, Veneer Mill, 507, 509, 511, 513 & 515 W. Sixth St., CINCINNAT), ‘s fulfill MP; tıºnſ 167 EAST 34TH-St., NEW YORK, By Special Appointment Electrical Instrument Makers to the New York State Hospital for Nervous Diseases, ELECTRO-MAGNETIC MACHINES, Portable Galvanic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, 1870, and May 30th, 1871. These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery Fluid. |M|| ||||||—|| ||||||}} PERMIANENT BATTERIEs, For Hospitals and General Practitioners, IET IIECTIE,OIDIEHS. For Eye, Ear, Larynx, Nose, Uterus, Wagina, Bladder, Ree- tum, Feet, Phrenic and Sympathetic Nerves, Eleo- trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. EXTRA (4TS FROM THE OPINIONS OF THE MOST EMIN ENT MEMBERS OF TELI PROFESS RON. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “NoTHING CAN EXCEED THE EFFICIENCY AND CONVENIENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” We are authorized by Prof. Hammond to announce em- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- proved and re-modified Instruments made by our Company. MEREDITH CLYMER, M. D., Prof. of Diseases of the Neº- vous System and of the Mind, &c., &c.—“I consider theºr Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prof. of Surgery, St. Louis:—“In neat- ness, compactness and efficacy, they can not be excelled.” ALFRED C. GARRATT, M.D., Boston :-"In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” Similar Testimonials have been received from JOHN J. CRANE, M. D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A. MURRAY, M. D.; CHAS. E. BLUMENTHAL, M. D.; E. C. SEGUIN, M. D.; ALLEN MAYNARD, M. D., Cleveland, 0.; Dr. C. WANNIE, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES KELLY, Florence, O.; Dr. JOHN BECKER, Brighton, Iowa; Dr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes- barre, Pa.; JOHN J. CALDWELL, M. D., Brooklyn, and many other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an Electrical Instrument for medical purposes. FOSTER’s IE'_A_TIEISTT Are furnished to Officers and Soldiers on Government account. I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb—why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMES A. FOSTEER, 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cincinnati, onio, or 172 Jef- ferson Avenue, Detroit, Mich- SAML. P. THOMAS T.A. I. I. O R, DEALEF IN English, French and Scotch GOODs, 34 West Fourth Street, CALL OR SEND FOR CIRCULAR AND PRICE LIST, crwczywarr. DIVIDED MEDICINES, PREPARED BY The Divided Medicine Com’y, CINCINNATI, OHIO. The Company have the honor of bringing to the notice of the Profession, this NEW AND ExcFEDINGLY Practical METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in, general. - The Divided Medicines are prepared by FREDERICK KRAUs, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MORE. - The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every square will consequently contain accurately measured quantities. - But not only SoLUBLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINES. . . 2 This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain; #. 3. #. 3, 1.0, and even idoo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. - Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE TO SPOIL BY ANY LENGTH of TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. - Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calls with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. - For Samples, Price Lists, and Agencies, address - 2688, Or FRFDERICK KRAUS, Chemist and Druggist, - Walnut Hills, Cincinnati, O. MR. FREDERYCK KRAUs: - CINCINNATI, February 15, 1871. Dear Sir—The specimens of your “ Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: SULPH:MORPHII....................... % grain in each square. ARSEN:ACID..........................1-20 grain in each square: ** CH IN INI .......................1 ** ** $6 CALOMEL *.......}4 “ ** 44 $ 4 COPPER -----------------0 * * * tº ſº % 66 BESPECTFULLY YoUBs, E. S. WAYNE, Analytic Chemist. TIEEE IFI} C T , T NT I. C. 205 Vol. 2.] [No. 18. *— S A T U R D A Y, M A Y 4, 1872. O R. I.G IN A L A R T I C L E S. —-º-º-º- “T H E H H S T © R. Y O F C E R E E R O-S P H N A L. NH E N IN G H 'H' I S. . . Compiled from Various Sources. the chapter from Stillé and including extracts Incorporating part of - from Köhler and Hunt. SYNoNYMs: Spotted Fever (Gallup), Typhus Petechialis (North), Malignant Purpuric Fever (Stokes), Cerebro- Spinal Fever with Cerebro-Spinal Meningitis (Gordon), JFebris Nigra (Lyons), Malignant Purpura (McSwin- ney), Pestilential Purpura (Banks), Black Death (A. Smith), Cerebro-Spinal Meningitis (Hughes, Law, Banks, Hayden, Moore and others), Epidemic Men- àngitis. Other less common synonyms are Typhus Syncopalis and Winter Epidemic; Fièvre Cérébrale, Céphalalgie Epidémique (Fr.); Nacken Staare, Gehirn á. Rückenmarks Entzündung (Gr.). The term Cerebro-Spinal Menigitis is, however, the only classical name, the only one which designates the seat and pathology of the disease. The medical historian takes peculiar pleasure in tracing back the recognition of every disease to the most ancient times. It is his delight, indeed, to dis- cover a lucid description of every malady in the works of Hippocrates. Passages whose obscurity per- mit as many interpretations as those over which theolo- gians continue to wrangle are translated with the fertility of imagination into indisputable evidences of the diagnostic acumen of the first great physician. Notwithstanding the fact that our knowledge of all diseases of the nervous system is even in our day de- plorably defective yet the most distinguished of the older medical historians claimed to have discovered the first portrayal of these affections in the writings of Hippocrates and Galen. Neither the old physicians of Coe, however, from their ignorance of the anatomy and physiology, to say nothing of the pathology of the parts concerned, nor their immediate or even more remote successors could have had any but the faintest concep- tions of the seat and essence of nervous diseases. The statement of Frank, then, that the first accurate descriptions of spinal meningitis are to be found in those - chapters of Hippocrates, Galen, Ballonius and Allenius which treat of the so-called pleuritis dorsalis is based— as unprejudiced examination of the passages cited clearly shows—upon that stasis of the spinal meningeal vessels which is the frequent, almost constant attendant upon inflammation of the posterior portion of the diaphragmatic pleura. - In the days of Hippocrates and Galen the dissection of man was considered a crime of such enormity as would invoke the direst anger of the gods; accurate anatomical or pathological knowledge of any disease, thus, was of impossible attainment. That any informa- tion, however faint, could have been possessed at that time upon the obscure affections of the spinal cord is negatived at once by the acknowledgement of the great physician of Pergamus himself who confesses how great was his joy to have been able on one occasion to See a human skeleton at Alexandria, by the study of which and by its comparison with the facts he had ascertained from dissections of the lower animals he had been able to increase his knowledge of and correct his mistakes in the anatomy of man. Indeed, it has been fully de- termined by reliable investigators who have thoroughly and laboriously worked over the barren fields of ancient medicine that the first section of the spinal column, as is seen in the writings of Nic. le Pois, Fernelius and Felix Pater, was made as late as the fifteenth century and then only in the most defective manner. Our knowledge of spinal meningitis dates from a period as late as the middle of the last century. Mor- gagni and Bonet described the disease with full histories of cases and reports of post-mortem sections in a manner so accurate and trustworthy as to serve as illuminated portraitures for the physicians of all times. It was the celebrated essay of Peter Frank, however, (De vertebralis columnae in morbis dignitate: Delect. Opuc. Tom. xi, Ticini 1792) which first promulgated the different inflammations of the spinal cord. He developed the origin of spinal meningitis as an inflam- mation of the membranes of the cord and contributed in his description of the various processes of inflammation ten fold more knowledge upon this subject than all observers before him. The first decade, then, of our own century furnished us more literature on spinal meningitis than all time previous to this date. Dr. Sanford B. Hunt (U. S. Sanitary Commission memoirs, 1867), quotes from Simon to the effect in 1837 when its importance first began to be recognised in France, few previous epidemics of the disease were on record. Yet it had been more or less known, he con- tinues, before that time. In Geneva in 1805, it killed thirty-three persons and from that time on it has been occasionally described. Yet there can be no doubt, that as an epidemic—and in that respect to be dis- tinguished from ordinary meningeal inflammations—it has existed from the earlist periods of medical record, Dr. S. G. Webber, of Boston, in the erudite essay to which was awarded the Boylston prize for the year 1866, thinks to very clearly establish its identity with epidemics 206 T IEEE IET: [MAY 4, 1872. C T , T TXT T. C. chronicled in Europe as far back as 1840. A close ex- amination of the various passages cited, however, still leave it doubtful as to the nature of the disease described. With the increase of medical publications we find this disease, or something which does not much vary from it in the prominent symptoms, recorded frequently; and it would encroach too much upon our space to specify the particular epidemics. In all of them we find no contradiction to the continuous statement of a disease, distinctly, but not extensively epidemic ; suddenly appearing and as suddenly passing away having its habitat in malarial localities, or where crowd poison was present; attracting attention and exciting profound alarm by the violence of its cerebral symptoms; and finally, presenting at all times—and not less now than in former years—a frightful percentage of mortality. No country in Europe or in N. America, open to in- telligent medical observation, has escaped this infliction. The localities that have been distinguished by its most severe invasions, during the present century, are Geneva in 1805; among the Spanish prisoners at Briançon in 1807; in the sick of the French army at Grenable in 1814, after the hardships of crossing the Alps in winter; and in the Parisian hospitals at the same time; during the winters of several years (1813–14–15) in Ireland; in Milbank penitentiary near London in 1823; among the galley slaves at Toulon in the winter of 1829–30; in numerous barracks in France in 1837 and continuing for several years to be confined mostly to the military; extending its ravages to civil life at Strasbourg in 1841; from which time its appearances are too numerous to quote, it having become a well recognized disease, although by far the best study of it that has met our eye is that made in 1865 by Dr. John Burdon Sanderson on the lower Vistula, in Northern Germany, whither he was dispatched on a tour of investigation by Dr. John Simon the distinguished medical officer of the Privy Council of Great Britain. Restricting our historical review of the disease to the epidemics of it which have occurred since the beginning of the present century, and, rising for a moment above its individual and local outbreaks, our attention is at once arrested by a circumstance which removes it from the category of endemic, and even of epidemic diseases, in the ordinary sense of the latter word, and entitles it to the name pandemic. Unlike typhus, and typhoid and yellow fevers, its rise and progress are connected with no antecedents of animal or other putrefaction; nor with any miasmatic, cryptogamic or analogous agent, like periodical fevers; nor with any telluric or aqueous emanation like dysentery; nor with a special poison like cholera, small-pox, or measles. All of these diseases have, moreover, a distinctly ascertainable starting point from which they widely extend ; or else their ravages are confined within comparatively narrow limits; but with epidemic meningitis the case is very different. Its outbreaks have occurred almost simultaneously in regions as widely separated as Europe is from America, and annually it has made a mid-winter attack upon towns and rural districts, the salubrious and unhealthy alike, completing the cycle of its progress in a period varying between ten and fifteen years. Three such periods, at least, have occurred during the present century. The first, of eleven years, began in 1805 and terminated in 1816; the second, of thirteen years, oc- curred between 1837 and 1850; and the third extends from 1856 to the present time, and has already lasted for eleven years, during which the disease has been almost constantly present in Europe, but absent during four years from the United States. These two condi- tions, of simultaneous appearance in widely remote places, and of annual recurrence for a series of years, characterize no other disease whatever. The first, indeed, is fulfilled by influenza; and it was perhaps a dim preception of the analogy we have pointed out which led one writer, at least, (Wilson), to imagine the two diseases to be identical, a proposition which at the present day may provoke a Smile, but hardly calls for refutation. But no other disease than influenza affords an example of the former condition singly, and none but epidemic meningitis of both combined. The first account of epidemic meningitis within the period we have referred to was published in 1805, by Vieusseux, who at once declared that neither he nor any of his colleagues had ever seen a similar disease. It is also worthy of remark, that in this particular epidemic a petechial eruption was a prominent symptom, that engorgement of the brain existed in most of the fatal cases, and that its historian describes it as “a malignant non-contagious fever.” If any doubts should be enter- tained respecting the identity of this disease with epi- demic meningitis, they will perhaps be dispelled by the account which Mathey furnishes of a dissection made in one of the fatal cases. He describes a gelatinous exudation as covering the convex surface of the brain, and a yellow puriform matter upon its posterior aspect, upon the optic commissure, the inferior surface of the cerebellum, and the medulla oblongata.” In every one of the following years, until 1816, the same disease prevailed either in Prussia, Holland, Rheinish Germany, Bavaria, or the east of France, but no where else in Europe; while in the United States it began its course in 1806, at Midfield, in Massachusetts, and between that time and 1816 it extended throughout New England and into Canada, the State of New York, Pennsylvania, and other States to the South and West, precisely as it has done during the recent epidemic. We possess no record of its occurrence between 1816 and 1822; but in the last named year, a local and * Bascombe, in his “History of Epidemic Pestilences,” speaks of * local epidemic at Roettingen, in Franconia, in the autumn of 1802, in which the young and strong were suddenly seized with pain and anguish at the heart and lacerating pains in the nape of the neck. In the worst cases the patient fainted, the limbs became rigid, and death closed the scene frequently within twenty-four hours from the com" mencement of the attack. MAY 4, 1872.] TIEEE E CIT, ITNTIC. 207 temporary appearance of the disease was observed at Vesoul, in France; in 1823 at Middletown, Connecticut; in 1828 in Trumbull county, Ohio; in 1830 at Sunder- land, England, and in 1833 at Naples. After four years of quiescence it entered again upon a wide and destructive career, which lasted from 1837 to 1850. During the first two years of its recurrence in Europe, it was confined almost entirely to France; but during the third and fourth years it appeared also in Italy and Algeria and at Gibraltar, without, however, retreating from its original territory, where it continued to prevail until 1849, breaking out meanwhile at various points of the north of England and in Dublin, and from 1845 to 1848 in Denmark. While the epidemic was thus spreading through Europe, it again appeared in the United States at places as remote as possible from trans-atlantic communication, and hundreds of miles distant from one another; in Louisville, Kentucky, in Rutherford county, Tennessee, and in Montgomery, Alabama. This took place in 1842; and in the follow- ing years, the disease appeared in Arkansas, Mississippi and Illinois. In 1848 it occurred again at Montgomery, Alabama, and simultaneously in Beaver county Pennsyl- vania; in 1849 it existed in Massachusetts and in Cayuga county New York, and finally at New Orleans, in 1850. It appears, therefore, that although the American epi- demic began later than the European, it reached its period of extinction very nearly at the same time. Between 1850 and 1854 epidemic meningitis had ceased to be heard of, when suddenly it broke out with destructive violence in Sweden, a country which had hitherto entirely escaped its ravages, and there it con- tinued to prevail during the six years from 1854 to 1860. During this period localepidemics of very limited extent or sporadic cases occurred in Dublin, London and in Stafford, England; and simultaneously the disease pre- wailed in several parts of the United States. On this, as on previous occasions, its starting points were remote from one another, as in North Carolina, where it ap- peared for the first time in March, 1856, and in the cen- tral portions of New York and Massachusetts at the commencement of 1857. To return once more to Europe, we find that hardly had the epidemic ceased in Sweden, than it reappeared in Holland during the winter of 1860–61; and in the following year, at the same season, it spread over a large extent of the Portugese territory. Germany, which had remained almost entirely exempt from the attacks of the disease since the first and very partial outbreak of 1806, was now the seat of an epidemic as widespread as that which had prevaded France. Beginning slightly in the summer of 1863, it acquired new vigor during the next winter, and for the two following years devas- tated almost every part of northern Germany, but, so far as we are informed, penetrated but slightly into the Austrian empire. Simultaneously (1865) a local epi- demic of the disease occurred in Dublin. The counterpart of this epidemic, as on former oc- casions, appeared in the United States. The first point at which it broke out was Livingston county, Missouri, in the winter of 1861–62; and during the same season it invaded Indiana, Kentucky and Connecticut. From 1860 to 1864 it prevailed in Ohio, and during the last named year in Illinois. Cases of the disease occurred at Newport, Rhode Island, in 1863, and in Vermont in 1864. In 1863 the epidemic began in Philadelphia, and has renewed its appearance annually until the present time. During the same period it prevailed in Maryland, Virginia, North Carolina, Alabama, and other Southern States. The coincidences which have now been pointed out are among the most striking occurrences in the history of this singular disease, and they are, as before remarked, characteristic of it alone. If there had been anything common in the origin of its epidemics, as climate, soil, or water, or the Social condition, age, sex, occupation or habits of the patients, a plausible, although even then an untenable, explanation of their simultaneous occur- rence might be suggested; but, in point of fact, no single circumstance was common to all, or nearly all of them, except their outbreak in mid-winter. It follows, there- fore, that, even at this stage of our inquiry, epidemic meningitis must be regarded as an exceptional affection, and, as before intimated, a true pandemic disease. Along with the more or less wide spread epidemics which have now been considered, several instances are on record of this disease occurring in groups of two, three of four cases, in localities where it never at any time assumed the epidemic form. Not to cite instances of doubtful import, we shall refer only to those observed in England, where epidemic meningitis has never yet been known to prevail. In 1807, Dr. Gerwis, of Ashburton, reported four such cases; in 1859, Dr. Day met with two such at Stafford; and in 1865, three cases were observed in London by Dr. Wilks, three by Dr. Orgle, and one by Dr. Martin. At the present time it is again prevailing as an epi- demic, not extended, but of considerable severity, in New York, Illinois, Iowa, and Ohio. -—sº-º-º----- A. C. A. D. E. E. Y O F M I E D I C I N E . JAS. GRAHAM, M. D., PREST., L. WOLF, M. D., Secry. Transactions April 29, 1872. Reported by Joseph Ransohoff. **=sºme Cerebro-Spinal Meningitis. DR. A. BRown reported the following case. L. H., aet. 6 years, American. Had been in delicate health for two months, complaining of pain in the right hip joint. Thursday, April 19th, the patient was attacked with nausea and vomiting, complaining at the same time of 208 EMAY 4, 1872. T H E CI, IISTIC. pain in the head and posterior cervical region. Sunday morning was apparently much better, but in the even- ing of the same day, the nervous excitement became intense, and attended with frequent shudderings and shrill outcries. The bowels having been unmoved for thirty-six hours, an enema of assafoetida and ol. ricini was ordered, which had the desired effect in a short time. Ordered also bromide of potassium in 5 gr, doses every two hours. Monday morning the patient was more quiet, pulse 72, temperature 99°. Hyperaesthesia well marked, and a twitching of the muscles occasionally noticed. The pupils contracted, and the tongue was readily protruded, but coated with a brownish fur. Sordes on the lips and teeth. Intellect sluggish. Ordered iodide and bromide of potassium, wine and beef tea and frequent sponging with mustard water, Tuesday, same as day previous. Rested part of the night. Again ordered an enema, which had no effect. Wednesday, the patient was worn, making no response to questions. Opisthotonos presented itself, and the patient frequently carried her hand to the back part of the head and neck. No tenderness of abdomen. petechia. Temperature 99°, pulse 90, respiration irreg- ular. The urine contained a slight trace of albumen. The bowels being confined, a mercurial purgative was administered. Thursday, no improvement, though bowels had been freely moved. The pupils well dilated, the right more so than the left. She was unable to pro- trude her tongue. Partial paralysis was rapidly super- vening. - The patient remained in this condition until this morning, [April 29th] at 9 o'clock when she expired. No DR. CARSON presented the pathological specimens of the case. The lesions in this case are not very well de- veloped, the amount of exudation being not so great as in the specimen presented by the speaker at the last meeting. There was, however, some opacity of the arachnoid membrane and a decided congestion of the superior and inferior surfaces of the brain. In this in- stance the spinal cord was not examined. DR. MUSCROFT stated that within the last few months he had seen several cases of brain disease which were unlike any that he had seen before. The first case was that of a girl, aet. 5 years. She complained of severe pain in head and back. She was partially unconscious, but intelligent when aroused. She had been attacked one day before the visit. There was a tendency to opisthotonos. Supposing this to be a disease of the brain and spinal cord, a mercurial purge, bromide of potassium and hydrate of chloral were ordered. The case however terminated fatally. The second case, was that of a girl, aged 9 years. Found the child vomiting. She had vomited for forty-eight hours previous to my visit. There was also a great tendency to sleep, as in the first case, I here also made but one visit, three days after which the patient expired. The third case was being treated for hooping cough. I saw the child about 8 P. M. when it was making desperate efforts to speak. There was also great disposition to extend the fingers; especially those of the right hand. The child died next morning at 2 o’clock. No post-mortem was obtained. The next case reported by Dr. Muscroft was that of a boy, aged 14 years. He was seized by an attack while crossing the street. While so doing, he found great dif- ficulty in controlling his muscles. When I saw him he was in a straight position in bed; the pupils of natural size but insensible to light. There was also a twitching of the muscles of the face and some opisthotonos. He lived one day after the visit. The Dr. added that all the cases of cerebro-spinal meningitis which he had seen terminated fatally. - s . - DR. ORR also reported a case of this disease, The patient was a girl one year old. The first thing noticed upon entering the room, was the position of the child. There was considerable opisthotonos. The next symp- tom manifesting itself was paralysis of the upper and lower extremity of the right side. The child was almost constantly sleeping and its eyelids continually drooping. Great sensitiveness along the spine, and upon the slightest pressure there, the child would scream. The pulse in this case was 148. Prescribed quin. Sulph. gr. ij. and sodii. brom. gr. Vij. every 4 hours. Ordered also mustard to be applied to the spine and cold to the head. At present the child is very much improved but not yet out of danger. - DR. REAMY also related two cases. The first was that of a child 16 months old. The little patient was attacked with vomiting in the night. The bowels were constipated. Pulse very rapid; there was a marked tendency to opisthotonos, the head being constantly thrown backward; the muscles, however, were not rigid. There was also a disposition to convulsions. Ordered potas, brom. gr. viij every two hours, after which potas. iod. and quinia were administered. The child made a. good recovery. The second case was also attacked by vomiting. The pulse rate was very rapid, and breathing rather difficult. Gave potass, bromid. gr. vij, every two hours. The sub- sequent treatment was similar to that given in the first case reported. This patient also recovered. DR, GOBRECHT stated that at present he had under his charge a case which at first he thought to be one of cerebro-spinal menigitis, but which turned out to be one of an entirely different nature. The patient was a boy seven years old. When first seen he was very stu- pid and entirely insensible. Head and skin were hot and dry; the pupils were neither dilated nor contracted but insensible to light. The pulse rate was 140 per minute. Slight tendency to opisthotonos also manifested itself. Supposing this to be a case of the disease under consideration, I put the child upon hydrarg. chlor. mit. gr. 4 every two hours, and ordered ice cloths to be ap- plied to the head. Saw the child again at 8 P. M., when it had a general spasmodic action. Then ordered a warm. bath and half teaspoonful of black assafoetida. The next morning the boy was able to recognise his parents, MAY 4, 1872.] TIH. H. C.I.INTI c. 209 but upon close inspection a fine varioloid eruption was seen on the body. The preliminary symptoms certainly resembled those of cerebro-spinal menigitis. DR. COMEGYS stated that he had no case to report, but that he had an opportunity of seeing numerous cases of this disease in the epidemic which prevailed in and about Oxford several years ago. He spoke of the great value of opium in these cases, and expressed his intention of treating all those cases which might come under his care, by the use of morphia hypodermically. He also considered ice bags applied to the spine of the greatest efficacy. DR. CARSON reports as follows: Within the last two days I was called to see a child in a very serious condi- tion. The child had been vomiting profusely. It was quite intelligent, and denied having any head ache. Took the hazard of diagnosing this case one of stomach trouble and treated it accordingly. Next morning the patient was improved. I was informed by the mother that it had cried out, and complained of violent pain in the head. I then put the child upon bromide of potas- sium. The next morning I found it nervous and occas- ionally starting out of bed, but no further vomiting. At present I have placed it upon the opium treatment. As yet in this case I do not risk a diagnosis. I also saw a boy (aet. 8 years) last Thursday who had been taken suddenly with a very violent headache. The principal symptom of this case was the behavior of the patient. He would frequently become maniacal and then he would attack the male members of the family only. There was no rigidity of the muscles and no tenderness along the spine. There was no vomiting and the pulse was 50 or 60. Isaw another boy in the same locality. This patient's symptoms were somewhat similar to those related of the preceding case. There was the same reduction in the pulse rate and there were also occasional paroxysms of laughing. - I have at present another case, in my ward at the Hospital. The patient is a vigorous young man aged 18. In this instance there is well marked rigidity, the skin is hot and the temperature 100°–102°. In this patient no brain symptoms have developed, the intellect being clear. At present the symptoms look more favor- able. This case is one of very slow development. DR. GRAHAM made a statement concerning the case he had reported at the previous meeting to the effect that the untoward symptoms had subsequently subsided and the child was now out of danger. DR. WHITTAKER read a short compilation of the history of epidemic cerebro-spinal meningitis. DR. ROSENFELT reserves a report upon four cases now in his care until results have manifested. DR WALKER reported a case of confluent small-pox after vaccination and D.R.CARson presented a patient with well marked progressive muscular atrophy. [The description of this most interesting case with the remarks of the speaker are deferred to the next number.] A GENERAL SURVEY OF • THE DEISEASE. Being Meissner's Abstract from Prof. Hirsch’s “Meningitis Cerebro- Spinalis Epidemica,” from its historico-geographical and pathogico- therapeutical standpoints, [Schmidt’s Jahrb., No. 136, 1, 1867, p. 89, et seq. - ºsmºmºsºmeºs In many cases the disease was quite isolated occurring at different places, in regions that had hitherto been unvisited by attack, and extended itself to distant regions overleaping the intervening places [sprungweise]. Only rarely did it manifest itself suddenly in great, devastating epidemics, to disappear as suddenly as it oc- curred. The duration of epidemics and their extent varies most remarkably, to such degree, indeed, that no average can be struck. The proportion of the number of cases to the number of inhabitants ranged from 0.3–20.5 per cent. In like degree the proportion of fatal cases varied, according as lighter cases were included or not, from 20–75 per cent. An average of 37 per cent is perhaps closest on truth. Mortality is greatest at the beginning of epidemics, it is at this time, too, that the duration of the disease is shortest. § Any relation to other epidemics cannot be established. In Sweden and Thüringen, scarlet fever was observed in conjunction, with it; in Montgomery 1848, and in Niessethal 1863–64, measles; much more frequently elsewhere typhoid and malarial fevers though Hirsch has observed, concerning the latter of these affections, that meningitis to a certain degree excludes malaria. The form and course of the disease are so varied that it is exceedingly difficult to sketch a portrait common to the greatest number of cases. It is just as difficult, too, to establish definite stages or forms of the disease. The portrayal of Hirsch, notwithstanding its truth to nature, exhibits only in general the form of the disease in a minority of cases from which most cases differ in numerous exceptions. A stage of prodromata does not by any means always exist, but when it does present the symptoms indicate partly an affection of the cerebro-spinal system and partly a general infection of the organism. Among the manifestations of the first class is vomiting, with at times perfect appetite and more especially cardialgic or colicy pains. This last symptom is only mentioned by Schillizi and Mayne ; according to Hirsch it is observed in certain epidemics almost constantly. The symptoms of the attack proper are well known. It is worthy of note that, instead of the usual constipation which charac- terises some epidemics (e. g., that of Sweden), a regular diarrhea may be present. Swelling of the spleen was never observed by Hirsh, by other observers as Mann- kopff, always. The skin is usually strikingly pale, paler than in any other acute disease. Hirsch does not con- 210 [MAY 4, 1872, TEEE CI ITTIc. sider the different eruptions, which are not infrequently observed, of critical significance. The ranges of pulse and temperature furnish no definite law; shortly before death, however, a considerable increase of both was ob- 2erved and this increase continues even a short time after death. In hyperacute cases with immediate collapse, no reaction occurs. The speedy emaciation and depression, present in even lighter cases and not seldom terminating in fatal marasmus, is most remark- able. - The disease manifests itself in the following forms of distinct type: A. According to the Gravity of the Symptoms : a. Grave Cases. 1.—Intensely acute cases in the form of meningitis foudroyante (meningitis siderans); - 2.—Grave cases with acute course and termination in death or most tedious recovery. g 3.—Grave cases with manifold complications which have a protracted course and finally terminate in death with typhoid manifestations, secondary accidents (especially hydrocephalus), sequelae or marasmus. b. Lighter Cases. 1.—With perfect development of symptoms attaining, however, only a moderate grade of intensity without, or with in only light degree, depression and terminating in recovery, or in rare cases, with sudden aggravation of of symptoms, in sudden death. 2.—With the characteristic symptoms but less marked, almost without fever, running usually a quick and always favorable course. c. Lightest Cases. 1.—With prominence of individual characteristic manifestations, the so-called abortive forms. B. According to the Type of the Disease: a. Cases with continuous or remittent type, the, by far, most frequent form of the disease. b. Cases with intermittent type. Certain modifications of epidemic cerebro-spinal men- ingitis are described more thoroughly, especially the abortive form which occurs more frequently towards the close of an epidemic and extends itself occasionally over a whole population ; at times to assume the fulminant form, which is else usually confined to the beginning of an epidemic, and which causes the great mortality at first. Further the intermittent form with quotidian or tertian intermissions which may manifest as well in the prodromatous stage as in its full develop- ment or during convalescence and which Ziemssen refers to an irregular [saccardirt) progression of the disease from the start or to a resorption of the exudation during resolution or convalescence. Hirsch subscribes to the first of the views propounded, discrediting the last. The prognosis in general is unfavoraple. It is de- termined in special cases by the rapidity of the course of the disease (stormy attack, absent or short pro- dromata give an unfavorable, cases of meningitis siderans an absolutely fatal prognosis), by the extent of the affection (prominence of symptoms of cord affection, trismus especially, is unfavorable), by the occurrence of signs of depression (coma, respirations above 60, very high pulse are very unfavorable), by the stage of the epidemic (at first more favorable than later), by the age of the patient (childhood and advanced age, above 40 is particularly unfavorable), by its complications (pneumonia is unfavorable, stomach symptoms are not of importance, exanthemata (except the petechiae of the later stages), parotiditis, epistaxis, as well as the variety of type of the disease are without special prognostic im- portance.) - The cause of the disease and its pathogenesis are as yet. but little known. Climate exercises only a very limited, perhaps no influenée at all. It occurs among the in- habitants of the Atlas mountains up to and above the 60th degree of latitude and from the Gulf to the states of New England. The season of the year, however, has a most decided influence as by far the greatest number of epidemics prevailed in cold seasons. The reason of this, however, is obscure: neither temperature, nor moisture nor conditions of soil showed anything definite. Of all circumstances, concerning the individual, age takes the first rank. In the rule childhood is most frequently attacked, and in the so-called military epi- demics the younger individuals, 18-24 years, suffered most while the advanced in age were seldom attacked in any of the epidemics. In Carthaus and Behrent, of 779 persons dead with the disease, 696, i. e., nearly 88 per cent. were under the tenth year. Of the 1297 dead in Sweden between 1855-1860, 889, i. e., 70 per cent were under 15 years of age. In the Bromberger epidemic (1864) of 141 patients 132, i. e., 93 per cent. were under | 7 years. In Zellin (1865) of 54 very sick, 47 i. e., 87 per cent. were under fifteen. - Sex has less importance. In general, the male sex is somewhat more subject to the affection than the female and there have been epidemics in which only boys have been attacked: yet there have been also others in which girls were preferably seized. Race and Social Differences seem to be of significance only when the social-hygienic circumstances were bad. Thus Hirsch cites numerous epidemics in which only negroes or only military or only civilians or only the inhabitants of certain places (garrisons, barracks, manufactories, blocks of houses) were attacked. In these close and crowded places the atmosphere becomes poisoned by animal effluvia and products of decompo- sition and in these factors Hirsch finds the chief element, not in the production of the disease, but in its occurrence and extension. Gasté in the epidemic in Metz 1839-40 first called attention to these facts and really succeeded, by enlarging and ventilating the garrisons, in diminish- ing the number of attacks. Still the proper cause of the disease is not to be found in these conditions. Its real cause remains unknown and is to be sought in Some peculiar poison. Epidemic cerebro-spinal meningitis, thus, is an infectious disease, which like dysentery, MAY 4, 1872.] T IEEE THE C T , ITNT I C - 211 diphtheria, etc., runs its course under manifestations of a local disease and in this way differentiates itself from malaria, typhoid diseases, acute exanthemata, etc. The contagiousness of the disease is denied by many authors, because there is no diseased product from the secretory organs or from the surface of the body; yet cases of transmission of the disease to other places are so numerous as to leave the question of contagion at least sub judice; from a practical standpoint affirmed. The diagnosis is only difficult of differentiation with cases of the sporadic disease and with tuberculous basi- lar meningitis. It is distinguished by the different symptoms showing a general disease, as, particularly, herpes and petechiae, by the absence of any injury. Fulminant cases exclude the idea of sporadic nature as the sporadic disease never occurs in this form. The tuberculous form is differentiated by the previous tuberculosis or scrofulosis, its longer stadium prodrom- orum and its more protracted course. Typhoid fever is recognised by its much longer prodromata, its very high temperature from the start, its pronounced gastric symptoms with seldom vomiting and especially in the beginning by its diminished secretion of urine and absence of spinal symptoms, later by its typical course, regular diarrhea and the peculiar typhomania resembling narcosis. The diagnosis, therefore, presents difficulties only when the genius epidemics of meningitis is com- plicated with typhus or when later in its course a typhoid condition is intercurrent. Lastly the inter- mittent form might be mistaken for intermittent fever but meningitis is recognised among other considerations by the absence of other malarial attacks and of an interval of pure apyrexia as well as by the inefficacy of lllllla, Q The therapy of different authors is so different and often so contradictory that Hirsch contents himself with merely detailing the various methods of treatment by means of which or rather after which improvement has been observed. The average mortality of 30–40 per cent. remains the same in all epidemics under the most diverse methods of treatment and it is very questionable whether venesection, cold, derivatives or narcotics exert any particular influence on the epidemic form of the disease. Of special importance, however, is a regulation of the diet and a regard to hygienic conditions. If the case demand it, suspected houses must be purified, Schools closed, etc. —mº-o-º- THE PATHIOLOGY OF EPIDEM IIC, CERE BRO- s|PINAL MIENINGITIS. An Abstract from Klebs (Berlin) “Beiträge zur Pathologie der Epid- misohen Meningitis (Virchow's Archiv., xxxiv. 3. p. 327) in Schmidt's Jahrb., vol. 136, No. 1. p. 103, 1867. 1. Pathological Alterations of the Nervous System. a. The Cerebral and Spinal Meninges. Purulent meningitis has its seat in the brain almost exclusively in the arachnoid and pia mater, particularly in the subarachnoid spaces at the base between the infundibulum and pons, at the cerebellum and in the fossa Sylvii, further in the temporal region over the convolutions and in the course of the veins. As a proof, however, that the inflammation is general, those parts of the pia mater which are not covered with pus are cloudy and dull, and exhibit a rich proliferation of cells. In the spinal cord pus is found more especially on the pos- terior surface, less in front, most abundant in the lower cervical and the lumbar regions while the cauda equina is sometimes free. Where the purulent deposition is rich the pia is smooth and shining, where it is less it is strewn with small purulent deposits often connected together in reticulae. These purulent accumulations do not by any means correspond in quantity with the anatomical alterations of tissue; this indicates a change of position in obedience to the laws of gravity. Where this change of position is easy as in the relatively large canal of the cervical region, where there is at the same time greatest mobility, but little pus is encountered, while in the upper dorsal region where the canal is relatively narrow, pus accumulates. This change of position, again, is favored by the so-called spontaneous motion of the pus cells (Recklinghausen). The dura mater of the cord participates in the disease rather oftener than this membrane in the brain. At the upper cervical and lower dorsal regions, patches of easily Separable adhesions are sometimes encountered between the pia and dura mater without any marked alterations in the structure of the latter. These patches are associ- ate with cloudiness and thickening of the apposed sur- faces or with thin pachymeningitic deposits. They are not to be confounded with the thread-like, linear ad- hesions which occur in health and depend upon anomalies in development. These latter are quite regu- larly arranged and are to be considered as medianaccessory ligaments to the anterior and transverse accessory liga- ments of the posterior surface. The quantity of the purulent deposit in the arachnoid spaces varies, often it is so insignificant as to be scarcely perceptible. Espec- ially in the older cases is an absence of pus deposits ob- served with secondary hydrorrhachitis or hydrops ex- vacuo and cloudy punctated or thread-like streaks upon the pia of a pale greyish hue. Sometimes fresh exudations are found at the base (Fischer and Hoffman) without any extension of the disease from the base upwards and this in those cases even where brain symp- toms were only observed subsequent to spinal symptoms. These circumstances meet with easy explanation by the fact that brain symptoms only manifest themselves when the accumulation of pus can no longer sink into the araclinoid cavities. It is hemmed in, then, by the limitation of spinal space and accumulates in the cranial cavity to induce first symptoms of irritation subsequently symptoms of depressions; we are not necessitated there- fore with Fisher and Hoffman to regard this condition as an exception to the rule that the primary inflamma- tion always begins in the brain. In the most recent cases, tough, thready, yellowish or greenish-yellow masses are found deposited in the 212 [MAY 4, 1872. TIEEE IED C T , T N T C - ". arachnoid spaces resembling in appearance many forms of catarrhal nasal mucus and thickly crowded, round granulated cells usually with a single nucleus contain- ing mucin (Virchow) and sodium albuminates. These mucous contents in which the usual elements of pus are absent, but which have been recognized by Hoppe Seyler in the ventricular purulent fluid of hydrocephalus internus, causes the reticulated arachnoid to resemble the mucous tissue of the umbilical cord. In the ventricles Klebs found the same tough, yellowish, puru- lent masses only exceptionally; generally only a Some- what increased, easily troubled [i. e., made cloudy] fluid with occasional fibrinous clots but without pus corpuscles. The origin of the arachnoid pus is to be sought unquestionably in the few cells which the arach- noid in normal conditions contains in the connective tissue reticulae of the subarachnoid spaces. The epithe- lial lining of these cavities claimed by Luschka, Klebs has not been able to discover although the free, rounded or angular cells, floating in the fluid resemble epithelial cells in appearance. The rare occurrence of pus in the ventricles is explicable, according to the author, by the fact that the ependyma is as little inclined to sup- puration as is the epithelium of the choroid plexus and a de novo development of pus cells from other immigrated cells is as little credible as is equivocal generation else- where. This immigration is possible, however, along the tract of the velum chorioides and in the further course of the lateral plexuses or from the plexus chorioides cerebelli as the arachnoid spaces seem to be in commu- nication with the fourth ventricle. b. Alterations in the Substance of the Brain and Cord. The changes of substanoe consist in an often very ex- tensive softening, or in a real purulent encephalitis or myelitis. The softening so particularly emphasized by Rollet is encountered more especially in the older retro- grade cases and consists in an Oedematous Saturation of tissue. The white substance has a gelatinous promi- nence on section and even when hardened in chromic acid is not capable of being divided in sections, falling apart in numerous radiated fissures from the filling of the perivascular lymph spaces (His) with serum. Any increase of cells or division of their nuclei is nowhere perceptible. By the imbibition of this fluid the nerve fibres become varicose and the nervous substance loosened in this way separates often large plates of cholesterime while else only very small crystals are formed The extensive motor disturbances which are occasionally observed with only an insignificant accumulation of pus in the arachnoid cavities would seem to stand in connection with this process of softening. Still we are not justified in regarding this condition with Rollett as a special form of disease. The cause of the occlema lies in the local formation of pus or its accu- mulation, to the degree of which it corresponds quite closely. It is not to be regarded, however as a simple maceration from the contact of the pus, as just at the base of the brain where the largest accumulations of pus exist, no softening is observed. Moreover, contact of the brain substance with pus for several days does not induce more extensive softening than when this contact does not exist. Different from this oedemations softening is the so-called granular softening in the course of the ‘’ smaller blood-vessels, in the white substance of the cerebrum as intimated by Lévy and Corbin and more accurately described by Tholozan. This is a yellow or white softening and is associated with the development of granulated cells. Just as different from this condi- tion is that appearance of disseminated purulent infiltration which depends upon embolic processes, is thus a true encephalitis granularis. These embolic pro- cesses are to be regarded as products of a complicating endocarditis which is, however, of rare occurrence as is any participation of the heart in meningitis though it has been mentioned by different authors, especially the French. In 71 cases of brain disease, Klebs found only two cases of this class. In the one case there were numerous abscesses in the white substance, the conse- quence of a gangrenous pneumonia, in the other abundant sclerotic patches were observed which consisted of very homogeneous, resistent, areolated connective tis- sue without a trace of nervous elements. (This individual suffered with chorea, a disease whose connexion with heart affections Addison and Kerkes more particularly have demonstrated. This fact may be of significance in explanation of the symptoms of chorea. The products of inflammation of the valves, de- tached and carried off into the blood current, would plug the capillaries of the middle layer of the cortical substance and entail in this manner disturbances in the connexion between the cortical substance and the motor centres). 2. Pathological Alteraticns of Other Organs. Changes in other organs are scarcely mentioned at all in the older reports although they are constantly present and are of the greatest importance in the interpretation of the process of the disease. In several rapidly fatal cases Klébs found small, scarce pin-head sized, bluish extravasations in the upper- most layer of the Corium and generally in the course of a sudoriparous gland. The connective tissue at these places showed a [no 71 process of proliferation, very like the most recent formations of similar character in the brain. How much the changed condition of the blood, how much the condition of the vessel walls contributed to the formation of these petechiae is still a question of doubt. The French, it is true, lay the most stress upon the first of these conditions as they found usually an in- creased quantity of fibrin in the blood [due to their copious venesections?]; but in the most of the rapidly fatal cases the blood is found dark, fluid and poor in fibrin as in typhus and other so-called infectious dis- €3SeS. Of much greater importance are the changes in the MAY 4, 1872.] TIEEE IEH C T , ITN. T. C. 213 great glands of the abdomen and in the muscles. The Spleen is usually tolerably small, very lax, the pulp a dark grayish-red, the follicles small and scant or rather numerous and enlarged. It was only in the perfectly recent cases that a soft fresh spleen tumor of any size was encountered, and it is questionable, there- fore, if the lax forms were not already in process of retrogression, if there was not a spleen tumor present before the manifestation of meningitic symptoms. The kidneys are rarely enlarged, somewhat more relaxed than usual, the capsule is easily separable, the surface smooth, gray or grayish-red with darkly injected venous stars (in recent cases); the cortical substance, on Section, is of cloudy, grayish-red hue, sometimes (even as Soon as the fifth day) pale, grayish-yellow, translucent; the medullary substance is sharply distinct, usually mark- edly congested. The tubuli uriniferi often contain very many fine fat cells so that they are dark by transmitted, bright by reflected light. Degenerated in like manner are the thicker coils in the medullary substance border- ing on the cortical, while the finer loops and the straight tubules remain free or contain only fibrin cylinders or casts. In many cases, moreover, marked catarrh of the papillae is observable, but nowhere is any increase of the cells demonstrable. - The liver shows a similar parenchymatous degenera- tion with granular, albuminous or fatty cloudiness of the cells. This organ is not at all or only but little en- larged, very lax, on section of a uniform dirty grayish- yellow or grayish-brown color, dry as if boiled, showing a great similarity to the liver of typhus abdominalis. The voluntary muscles early show affection extremely extensive in character. In recent cases their fibres exhibit fine granular deposits so that they would seem to be strewed or filled with an extremely fine dust. This fineness of the fat molecules differentiates this dis- ease from the muscle changes in other toxic affections and seems to influence also their gross [macroscopic, naked eye] appearance. While in phosphorus poison- ing, the muscles are of a dirty grayish-red pale color; in carbonic acid poisoning, cherry-red; in typhoid fever, dry and dark violet-red, in epidemic cerebro-spinal meningitis, they are less characteristically colored being somewhat dry, lax and brownish-red. In consequence of this degeneration, the contractile substance seems to disappear, and such a degree of emaciation ensues as Scarcely occurs in long continued and exhausting dis- eases. In protracted cases this atrophy is attended with an exuberation of the cells of the connective tissue leading to suppuration and abscess formation similar to that of poisoning by carbonic acid gas but Without the subsequent necrosis of muscle snbstance. The muscles of the heart show a similar, but altogether much less degree of fat infiltration; the heart is usually lax, its substance is grayish-red. The changes of other organs are much less constant. The lungs in recent cases usually show a marked hyperamia, even splenisation of the deeper portions; in later stages often patches of broncho-pneumonic inflammation. The lymph glands are usually reddened, else normal; the solitary glands of the intestine are often moderately swollen. Disturbances of sight and hearing seem to occur more in the later stages and as sequelae. They fall rather into the department of the clinician than in that of the anatomist. Only in one case, where deafness developed as early as in the course of the first few weeks did the oppor- tunity present of investigating its cause. In this case both auditory nerves were extremely soft, Oedematous and of a white color. Under the microscope these nerves and their terminal apparatus, in which Gerhardt thinks to find the cause of deafness, were perfectly normal. The cavity of the drum, however, exhibited the remains of an extensive otitis interna in the shape of numerous, firm, vascularised, tensely stretched bands of connective tissue extending out from the bones of the ear in every direction, to the walls of the cavity and rendering the bones immobile. Such a condition as this, according to Lucae, is of itself sufficient to produce deafness of high degree. -—sº-o-º- G E N E R A L C O N C L J S H O N S . & After a Thorough Review of all the Works on the Subject of Cerebro-Spinal Meningitis up to 1867. IBY DR. H. MEISSNER, (Leipsic). Trom Schmidt’s Jahrbücher, Vol. 167, 1867, p. 123. From all the observations hitherto recorded, it follows that epidemic cerebro-spinal meningitis shows in the different places of its occurrence an extraordinarily different form. While in places, as in the orphan asylum at Vienna, it occurred in considerable extension but with little violence and in other places as in Einbeck extended over a whole population, it presented itself in still other places in scattered or perfectly isolated cases so that an epidemic basis could be recognized simultaneously in distant regions. An individual pre- disposition is, in general, not to be denied. Preferably, in many instances almost exclusively, it attacked children; yet there have been epidemics in which only adults, soldiers, etc., have suffered. Most authors ob- served the disease in individuals else perfectly sound; a few on the other hand more especially in weak and sickly persons. The general sanitary condition of popu- lations attacked, according to some was unusually good, according to others there prevailed at the same time other epidemics, measles, scarlet fever, diphtheria, rheumatism, intermittent, typhoid even recurrent fever in such manner that they seemed to stand in more or less intimate connection with each other. 214 [MAY 4, 1872. TIEI IEH C T , T INT I. C. Climatic and other telluric influences are, in general, denied; yet the cold season exercises usually a definite influence on the outbreak of the disease, and Dr. Karg believes that by maintaining the temperature of children and by preventing the influence of certain changes that he allayed the epidemic in Vienna. Of most significance in influencing an outbreak if not in inducing the disease are unfavorable hygienic circum- stances of every kind, over-crowding in badly ventilated places, the circumstances of poverty; the prevalence of the epidemic in winter, in certain institutions, among the lower classes, the military, etc., is to be partially explained in this way. * The symptoms and anatomical changes in other organs are referred by some [Klebs and others] without exception to the local disease of the envelops of the nerve centres, by others, on the contrary, in part, at least, to a general cause. With such a difference in the facts and views cited, it is not strange that there. should be such difference of opinion as to the entity of the disease. Klebs believes in a local disease of the brain and cord caused by atmospheric and hygienic con- ditions as in pneumonia which sometimes assumes an epidemic character, while most authors certainly hold fast to the originally constitutional origin of the disease and its development by infection. As a symptom of constant observation in Neuter- shausen, not yet observed elsewhere, Baur emphasizes pain along the tensely stretched carotids. Further, attention is called by many authors [Mannkopff, Klebs and others) in opposition to Niemeyer, to a constant enlargement of the spleen, subsequently followed by its relaxation and atrophy. Finally we may mention here the polyuria observed by Ziemssen and Hess, and the gyclosuria noted by Mannkopff as signs of an alteration of the fourth ventricle and its vicinity. In the pathological anatomy of this disease, numerous new and notable results have been furnished by micro- scopic investigation. The pus in the meninges which collects in the arachnoidspaces in the form of a thready, yellowish-green, mucous mass is characterised according to Virchow (Klebs) by containing mucin which is not usually pres- ent in pus and has only been detected by Hoppe-Seyler in the fluid of the ventricles. In the organizing exuda- tion Orth has observed granule formations which might confound the appearances with tuberculous meningitis. Klebs explains the presence of pus in the ventricles by immigration from other places as no pus can be devel- oped from the ventricle walls. Mannkopff found pus in the central canal. Of particular value in connexion with the extreme hyperaesthesia of the whole surface are the changes in the neighborhood of the posterior nerve roots Rabus observed pus in them and in the spinal ganglia: Ziemssen, once, a cheesy exudation in the same places: Orth, new formations of connective tissue in the dura-mater spinalis about the posterior nerve roots. Orth always observed considerable fluid in the spinal Sac and hydrorrachis is also noted by Klebs. Mende mentions fatty degeneration of the brain itself and granular destruction of many parts of the brain; Köllner, amyloid degeneration and pus cells with fibres of connective tissue occurring in masses. As to the condition of other organs the parenchym- atous degeneration of the liver and kidneys, the granular degeneration of the muscles (Klebs) and the cloudiness of the heart muscle fibres are to be specially noted. Finally concerning diagnosis, it is to be remarked that the sporadic form cannot by any means always be certainly differentiated from the epidemic form, that mistakes with tuberculous or meningitis from caries are easily made and that the supervention of the disease upon a previous injury may be of forensic importance. – sº-º-º- MEDICAL NEws MENINGITIS IN NEw York.-Cerebro Spinal-Men- ingitis is now quite prevalent in New York and vicinity, and threatens to become epidemic. Cases are also re- ported in Buffalo. SPOTTED FEVER IN BROOKLYN.—There were fifteen deaths from spotted fever, in Brooklyn, week before last. —sº- ©-º- CORRESIPON OPENCE. SoLON, IoWA, APR. 24. EDS. CLINIC: We are having a fatal epidemic of “Cerebro-Spinal Meningitis.” Our efforts are of little avail in its treat- ment. Please give usan article on this subject in “THE CLINIC.” It will be hailed with joy by all its readers, especially where this fearful disease prevails. I am very respectfully yours. G. D. Darnall, M. D. —e--- CLINICAL MEMORANDA. The Temperature of Cerebro-Spinal Meningitis. BY EDWARD LoNG Fox, M. D. From the Med. Times and Gaz., April 2, 1870. In this disease we lose the general regularity of ther- mometric phenomena met with in the maladies pre- viously mentioned. In the three cases tabulated with this paper, and given me by my friend Dr. Edward Collins, of Dublin, the variations of temperature are exceedingly striking. In Case 25, Ellen D., aged 16, MAY 4, 1872.] 215 admitted on the fourth day with a temperature exceed- ing 104°, the thermometer seemed to show a descending course from the sixth day to the thirty-fifth, when she left Medical observation, having lost the left eye, and having become totally deaf. But, during this course of thirty-one days, the temperature had, on several oc- casions, manifested considerable exacerbation for the space of twenty-four hours at a time. In Case 26, John D., aged 10, not admitted until the twelfth day, the disease throughout assumed an irregular remittent type, differing very much from the former case, and death ensued with a temperature of collapse 94, 2–5ths”; whilst, in Case 27, W. H., aged 22, death occurred at the end of the first week, with a temperature above the normal, but not higher than is usually seen in tuberculous men- ingitis. This case bears out Dr. Sanderson's observa- tion that the temperature is elevated even in the early stages. The temperature was noticed by Dr. Sanderson as constantly elevated at all stages of the disease, seldom falling below 100°Fahr. The highest point was just at, or immediately after, the close of the symptoms of in- vasion—viz., 103° to 104°, or higher in children. Sub- sidence of pains and general improvement were always coincident with lower temperature, and vice versá. This point was especially marked in Case 26, where the con- stantly occurring remissions coincident with temporary general comfort and relief of all distressing symptoms were very remarkable. Niemeyer, who, with Dotzauer and Lindrum, holds strongly the local theory of the disease, states that, in his experience, the temperature on the first and second days was often but slightly raised. It was only a little while before death that it rose as high as 104° or more. It is impossible to speak definitely of an ascending, a stationary, and a descending period in a disease that not only varies exceedingly in duration (from a few hours to many weeks), but also in its tendency to remis- sion and exacerbation. The only point that, with some exceptions, seems generally to have been observed, is that the acme is not reached until after the symptoms of invasion are over. An irregular defervescence may commence immediately, or may be delayed for several weeks, during which interval a middle period, that can scarcely be called stationary, is met with, with a ten- dency in the temperature to remit to the extent of four or five degrees, but to rise again to the maxim point, or Very near it. Wünderlich distinguishes three chief varieties of this disease—one rapidly fatal, and showing a very high temperature shortly after the commencement of the ill- ness, which is maintained for several days, and is still further raised at the moment of death, even to 108°. Post-mortem elevations may also occur in this form. Secondly, a light form, with fever of short duration, though often of considerable intensity, and with very irregular course. Defervescence occurs more or less by crisis, but with some exacerbation. Thirdly, a more or less protracted variety, in which the height of tempera- TIE-ITEH C T , I INT T. C. ture varys considerably. This irregularity is considered by Wünderlich to depend on successive complications of disease of the bronchi, the lungs, the intestines, the serous membranes, etc. The distinguishing phenomena, therefore, as regards temperature, will be (first) its great irregularity; (sec- ondly) its maximum point being in most cases below that of typhus, enteric fever, and scarlatina; and (thirdly) its relation to the pulse. Ziemssen says that the temperature is so irregular that few of the curves resemble each other, and Dr. Bäumler has made a similar observation. The experi- ence of the Philadelphia epidemic was that the tempera- ture was lower than in any other typhoid condition; and in the Irish epidemic of 1867–8 it was comparatively low, and in one case mentioned by Dr. Stokes the high- est temperature recorded was 98.8°. Dr. Sanderson found that, with high temperature in this disease, the pulse assumed the character of less arterial tension, but there was no discernible relation between its frequency and the stages of the disease, though the pulse rate fluctuated from time to time. Wünderlich observes that during the pyrexial periods of the disease the pulse is at or below the normal fre- quency, and only becomes quicker when the tempera- ture has become normal, and similar observations were made in many cases in the Irish epidemic of 1867; but the opposite condition is often met with. Indeed, Dr. Collins found its frequency in almost every case greater than natural, and he states that its frequency, its force, its volume, its regularity, and other qualities are subject to repeated and often inexplicable changes. In the three cases noted with this paper the frequency of the pulse bore a general relation to the height of the tem- perature, with occasional exceptions. Death, which occurs most usually from apnoea, is ac- companied by a high temperature in the majority of cases; but instances do occur in which the fatal event is ushered in by the temperature of collapse. The irregularity of temperature alone will serve for the diagnosis of this disease; but with the additional symptoms of cerebral respiration, vomiting, the peculiar position in which the patient lies, the delirium, and in some epidemics the eruption, a mistake will seldom be made, except in those very rare instances in which the temperature Somewhat simulates that of enteric fever. The general irregularity will help to distinguish it from typhus, of which disease Dr. Murchison considers cerebro-spinal menigitis only a form. The main diffi- culty is between this disease and some forms of acute tuberculosis; but patients suffering from the latter malady do not often experience that relief from distress- ing symptoms during the remissions of temperature that is so remarkable in cerebro-spinal menigitis. It must be confessed, however, that, in rapidly fatal cases, neither the temperature nor any aggregation of symptoms will suffice to distinguish this disease from some examples of tuberculous meningitis, 216 [MAY 4, 1872. T IEEE TEE C T , T INT I C. QUININE AND OPIUM IN SPINAL MENINGITIS.—Dr. C. W. Packard details the clinical history of several cases concluding with the follwfng remarks: The diagnosis of this case presented some points of difficulty. In many respects the symptoms resembled those met with in remittent fever occuring in a person of strong hysterical tendencies. Throughout the disease she had a fixed and placid expression of face, and looked as if she would get well. On the other hand, she had only one decided perspiration during her sickness, and quinine in large doses had no effect in checking the ex- acerbations of fever. For example, on February 15th, the morning temperature had fallen to 98°; twenty grains of quinine were given and retained, and the evening temperature rose to 105°. On the following morning the temperature was 100°; the quinine was re- peated, and the evening temperature was 104.” After this no medication was attempted beyond the exhibition of an opiate at night when the patient was very restless or delirious, the opium having been found to act more efficiently than any of the ordinary Substi- tutes. The quieting effect of opium was still more marked in the case of the boy above reported. Here the tr. Opii was given in five-drop doses every hour, and its effects carefully watched. There is no doubt in my mind that for twenty-four hours it so far steadied the nervous sys- tem as to stop the convulsions, and control the irregular action of the pupils and of the heart. Full narcotism was not produced at any time, the pupils being only moderately contracted, and the respiration even less than 30 in a minute.—N. Y. Med. Rec., Apr. 15, '72. MORPHIA HYPODERMICALLY IN CEREBRO-SPINAL MENINGITIS.–Morphia has been used in this way in the treatment of cerebro-spinal meningitis by Traube, Bois, Lorent, Niemeyer, Ziemssen and Hess, Thomas, and Neynaber. In one case characterized by pains in the sacral region and in the lower extremities, the injections were made by Traube into the nates. Pain was silenced instantly. The general condition, however, was always worse after the injections; there was a still greater increase of the sensibility. The intervals between pains were longer and easier without it than with it. According to Traube this depends upon the effect which opium always exer- cises in acute inflammatory diseases, on which account the use of this agent in this way is, in the rule, to be discarded. Bois, on the other hand cites a case in which an injec- tion of 8 ctgr. morph... muriat. immediately checked the extremely painful convulsions and brought the patient into a deep sleep. Lorent saw the eccentric pains in chronic spinal menigitis disappear transitorily. According to Niemeyer subcutaneous injections of morphia were made in the epidemic of Rastadt and Carlsruhe as a palliative for the great restlessness and jactitation. “In many cases the desired result seemed to be obtained for a short time.” Ziemssen and Hess used morphia both subcutaneously and per stoma; the first more especially in the violent exacerbations and in which a speedy effect was obtained. They never observed any disadvantages resultant, on the contrary, such marked palliative effects that it seemed, next to the applications of cold, the most indispensable agent in treatment. In the last session of the Society of Phys- icians and Physicists, Thomas expressed himself in its favor, Neynaber against it.—Die Hypoderm. Injection, etc., Eulenburg, Berlin, 1867. TREATMENT BY PHYSOSTIGMA.—Dr. N. S. Davis (Chicago Med. Eacaminer, Apr. 1,) gives notes of treat- ment in forty cases under his observation since Feb. 1. From this paper we clip the following: Recollecting that the Calabar bean had been used with apparent success in tetanus, and that I had used it with benefit in several cases of muscular rigidity from irritation of the nervous centres, I made the following prescription: - JR. Tinct Calabar Bean, 3f. Fl. Eact. Ergot, 3.jss. Mix. Gave half a teaspoonful every two hours, and omitted all other medicines. At the end of twenty- four hours the patient was found simply more quiet, the pulse a little slower, and the respiration more regular. The treatment was continued without change. At the end of the second day the patient had ceased to com- plain of pain in her head, had slept several times for half an hour to an hour; the retraction of the head was decidedly less; mind was clear; the mouth moist; and the urine free; but she seemed feeble. More simple nourishment was ordered, and the medicine continued at intervals of three hours. The case continued to steadily improve; and on the fifth day after the commencement of the use of the Calabar bean and ergot, the muscular rigidity had entirely ceased, and the patient was con- valescent, though emaciated and feeble. The medicine was continued three times a day several days longer, and a combination of extract of malt and the compound syrup of hypophosphites, in addition to nour- ishment, were given to aid in restoring nutrition and strength. Since that time I have used the Calabar bean, either alone or in combination with ergot, in nearly all the cases that have under my care, and cer- tainly with more apparent effect in controlling the dis- ease than by any other remedies I have tried. RECOMMENDATIONS OF THE AMER. MED. Assoc. COMMITTEE.—A Committee of the American Medical Association reported favorably on the sulphate of quinia in large doses, given at the very beginning of the disease. In some instances the drug seemed to abort the attack. The committee speaks also of the favorable results reported from the combined use of ergot and chloride of iron. Some American physicians have given ergot in combination with belladonna, and belladonna in combination with quinine, but with equivocal benefit. Mercurials have been freely used, particularly in the form of calomel, but their effect has been most question- able, except as purgatives. Their indiscriminate use is to be utterly condemned, and their use at all to be dis- countenanced. A host of other medicaments have been made use of, of which it is requisite to note only iodide of potassium, bromide of potassium, and arsenite of potash. The circumstances under which the two former drugs have been used, and are most likely to prove beneficial, will suggest themselves to the practitioner. It does not appear that any decided good has arisen from their administration. In protracted cases of convalescence the arsenite of potash may prove a valuable remedy. COLLEGE ANNOUNCEMENT. THE SPRING COURSE closes Friday, May 10. The regular attendance of the class [85 in numberl throughout the entire term is the best evidence of the appreciation of the practical system af instruction. A fine lot of most beautiful microscopic preparations from abroad—again the private munificence of a citizen of our city— is gratefully acknowledged as having contributed no little towards the interest of this part of the course, and as constituting a valuable addition to the College Museum. THE DISPENSARY SERVICE will be continued throughout the summer at 9–11 A. iſ, to which medical vior. to the city are at all times cordially invited, and on sp. 1, -'72, A SPECIAL COURSE on Microscopy, Electrotherapy, Bandaging, etc., will precede the regular winter session which commences on the first Monday in October newt. J||NF||RTS, \P/ Carriage Manufacturer, Nos. 9 and 11 East Sixth Street, bet. Main & Sycamore. I MAKE NOTHING BUT First czass wronx, Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of - LIGHT FAMILY CARRIAGEs Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive variety of light elegant designs of different cost and finish. In vehicles especially adapted to PHYSECHANS” GSE, The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. - The superiority of my light gentlemen's buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price s tº g lication. Ref S &s // * - F lists furnished on app º € * <\º Ny to Dr. W. W. Dawson and all the leading º s Physicians in the city and heighborhood. List of Pharmaceutical Preparations, NiANUFACTURED BY Jonºv wrºzºr & arozzºn, FHILADELPHIA. - º, ELIX PHOS. IRON, QUININE AND STRYCHNIA, - ELIXIR OF GENTIAN FERRATED, ELIXIR WALERIANATE OF AMMONIA, (Goddard’s Formula,) ... -- ELIXIR VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, Iron, with Phosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Hron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK, - ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Liime, Soda, Potassa and Iron, BITTER WINE OF IRON, Citrate of Iron and Peruvian Bark, e º FERRATED CORDIAL ELIXIR, ELIXIR, CALISAYA BARK, WINE AND BISMUTH, ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, * - FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, * - TASTELESS COD LIVER OIL, TASTELESS CODLIVER OIL. FERRATED, - * BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and sherry wine, ELIXIE VALERIANATE OF STRYCHNIA, WINE OF PEPSIN SYRUP SUPERPHOSPHATE OF IRON, y * ELIXIR OF BISMUTH, COMP. FLUIDEXT, EUCHU AND PAREIRABRAVA. sIJIPE*Os][TOE&LEs. Bectum, Vaginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great eare, and of every variety of combination. Lists sent on application. SPONGE TENTS.—For the Urethra, of every size and style, made of finest quality of sponge. William Autenrieth, ROBERT CLARKE & GO’S. No. 71 wrest sIxTH strºr, BETWEEN WAINUT AND WINE, CINCINNATI, OHIO, MANUEACTURER OF AND DEALER IN III || || |||||III, Abdominal Supporters, Trusses, CTUB-FOOT SHOES, SPINAL APPARATUS, ETſ Keeps constantly on hand a full variety of Metalic and Eubber Syringes, Storm.ach Purm ps, Etc. STOCKINGS FOR WABDCOSE WEDNS, Scoeial attention given to the fitting of Apparatus for Deformities. gº Agent for DR. L. A. BABCOCK'S Silver Uterine Supporter, -ALSO– DR. AHL'S POROUS FELT SPLINTS, —A LSO– DAY's spi, INTs -AND- THE AMATEUR MICROSCOPIST. Small 4to. LIST of New . . . - - º MHL iBTH in Mºulis inſ; GREEN'S PATHOLOGY AND MORBID ANATO MY, 8vo. Cloth. $2 5o DUCHENNE'S LOCALIZED ELECTRIZATION. 8vo. $3 oo DILLENBERGER ON WOMEN AND CHILDREN'S DIS- EASES. 12mo. $1 75 • BENNETT ON PULMONORY CONSUMPTION. 8vo. $1 5o FIRST HELP IN ACCIDENTS. 12-mo. $1 5o BEASLEY'S DRUGGIST RECEIPT Book. 8vo. $3 50 ECHEVERRIA ON EPILEPSY. 8vo. Cloth. $5 oc - HOWE ON EMERGENCIES. 8vo. $3 oo HAMMOND ON NERVOUS DISEASES. 8vo. $5 bo RINDFLEISCH'S PATHOLOGICAL HISTOLOGY. $6 oo WARINGS’ PRACTICAL THERAPEUTICS, 2nd Am. Ed. 8vo. Cloth. $5 od Leather. $6 oo -- SCUDDER'S SPECIFIC MEDICATION. 12mo. Cloth. $2. 5o TANNER'S HANDBOOK OF OBSTETRICS. 12mo. $2 oo WAN BUREN ON DISEASES OF THE RECTUM. 12mo. Cloth. $1 5o FLINT’S EXAMINATION OF URINE. 12mo, Cloth. $1 oo VOGEL ON DISEASES OF CHILDREN. 8vo. Cloth. $4 5o BEARD AND ROCKWELL’S MEDICAL AND SURGICAL ECECTRICITY. 8vo. Cloth. $4 50 ATTFIELD'S MEDICAL CHEMISTRY... 12mo. Cloth. $2. 75 Leather. $3 25 BARTHOLOW’S HYPODERMIC MEDICATION. Cloth. $1 5o TURNBULL's DISEASES OF THE EAR. 8vo. Cloth. $5 od TILT'S CHANGE OF LIFE. 8vo. Cloth. $5 od NEUMANN'S HAND-BOOK OF SKIN DISEASES. . Cloth. $4 oo ANSTIE ON NEURALGIA. 8vo. Cloth. $3 oo. PANCOAST'S OPERATIVE SURGERY. 4to., with many plates. $10 oo HOOD ON BONE SETTING. 12mo. $1 50 RINGER'S HAND-BOOK OF THERAPEUTICS. 8vo. $4 oo HOLBROOK's PARTURITION witHouT PAIN. 16mo. I 2, IITO, 8vo. - $1 oo gº PROCTER'S LIGHT SCIENCE FOR LEISURE HOURS. 12mo. $1 75 BERNARD's PHYSIOLOGY OF THE HEART: 50 cts. BARNES’ OBSTETRICAL OPERATIONS. 8vo. $4 50 NICHOL’S FIRESIDE SCIENCE. 12mo. $1 50. WOHLER'S MINERAL ANALYSIS. 12mo. Cloth. $3 oo PLATTNER'S MANUAL OF ANALYSIS WITH THE BLOWPIPE. 8vo. Cloth. $7 50 JEFFRIES ON THE EYE. 8vo. Cloth. $1 oo MANSFIELD, A THEORY OF SALTS. 8vo. Cloth. $4 oo JEFFRIES ON THE SKIN. 8vo. Cloth. $1 oo GARDENING FOR PROFIT. 12mo. Cloth. $1 5o PRACTICAL FLORICULTURE. 12mo. Cloth. $1 5o . FULLER'S SMALL FRUIT CULTURE. 12mo. Cloth. $1 5o WOODWARD'S COUNTRY HOMES. 12mo. Cloth. $1 50 DARWIN'S ORIGIN OF SPECIES. 12 mo. Cloth. $2 oo ARTHUR'S TREATMENT AND PREVENTION OF DE- CAY OF THE TEETH. 12mo. $1 50 TYNDALL ON LIGHT AND ELECTRICITY. 12mo. $1, 25 $1 75 BOOKS IN PREPARATION. BRYANT'S PRACTICE OF SURGERY. BARNES ON DISEASES OF WOMEN. ROBERTS ON RENAL DISEASES. GUERSANT, SURGICAL DISEASES OF WOMEN AND CHILDREN. - Medical, Scientific, and other Catologues sent on application. Any book in the above list sent by mail or express, free of charge on receipt of price. * S. W. EHiott’s Saddle=bags 65 West 4th Street, Cincinnati, Ohio. O. D. O. R. L.E. s.s A.N. D. P. A. L.A.T A. B. L. E. In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERs & BARTLWTT, of Portsmouth, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. - - Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. - In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be Volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachilic Affections, in Chronic Rheumatism, &c. * The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. & JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. ººzººlºº C = . rº- - * * —L 2Kll-X.º.º. 23–º::= º E. -> ~! ii§ R . | i g i #| || |ll. º! sº º §§ §§ -º-, -º- 9. ºf Hº: f jº , ºft| º fº ºil ||2 sº º º ºf w i; º: :############2. ############### -º-ET: § - É= CINCINN ATI. --~~~ E" A. C. TCſ L T Y . J A M E S G. F. A. H. A. M., M. D., DE AN, Professor of the Theory and IPractice of Medicine and Clinical Medicine. ROBERTS BARTHOLOW, M.D., W. W. DAWSON, M.D., Professor of Materia Medica and Therapeutics. Professor of Principles and Practice of Surgery and Clinical Surgery W. H. GOBRECHT, M.D., C. D. PALMER, M.D., Professor of Anatomy. Professor of Medical and Surgical Liseases of Women. P. S. CONNER, M.D., | - T. A. REAMY, M.D., Professor of Surgical Anatomy. Professor of Obstetrics and Diseases of Children. JAMES T. WHITTAKER, M.D., JOHN L, CLEVELAND, M.D., I’rofessor of Physiology. Demonstrator of Anatomy. SAMUEL NICKLES, M.D., CHARLES KEARNS, M.D., Paofessor of Physics and Medical Chemistry Assistant to the Chair of Surgery * W. VV. SEELY, MI. D., IProfessor of IDiseases of the Eye and Flar, and Secretary of the Faculty ,--~ E. NoblE, Janitor, College Building, Sixth St., bet. Vine and Race —ms. T. Louis Brows, M.D., Prosecutor of Anatomy. -ms- Printed and Published by Non R1s & M URRY, Medical College of Ohio Building, Cincinnati. HE CLINI C. PUBLISHED EveRY SATURDAY. T E R MS-$2.00 a Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editof $ w All Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer, vol. 2. C IN C IN N A TI, tº º ºs Editor. JAS. T. WHITTAKER, M. D. No. 101 West Ninth Street, Cincinnati, _A_SSO C.I.A.T.E. EIDITOIF.S. - W. W. D.Awson, M. D. THAD. A. REAMY, M. D. P. S. ConneR, M. D. . C. D. PALMER, M. D. W. W. SEELY, M. D. SAMUEL NICKLEs, M. D. CHAs. KEARNs, M. D. JNo. L. CLEVELAND, M. D. RoberTS BARTHoLow, MI. D. W. W. SEELY, M. D., - * ~ * sº tº * > TREASURER. No. 118 West Seventh Street, Cincinnati. C L J B R A T E S, 4 Copies to one address * * * * * * * * * * * * * * * * * * $ 7.00 6 & 4 & & 10,00 12 § { “ -------------------------------------................. 18.00 C O N T E N T S. *== Page, or IGINAL ARTICLEs Surgical Clinic of Prof. Dawson............ * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * ......217 Progressive Muscular Atrophy by Wm. Carson, M. D....... tº a tº e º s e º ºs e º ſº e 218 ACA DEMY OF : M IEEEDICHN. E. . Transactions May 6, ’72. Cerebro-Spinal Meningitis.-Corrections—Cases by Drs, Thornton and Muscroft.—Specimen by Dr. Reamy.................. 219 TRANS LATION Torticollis, Clinical Lectures at “La Pitie” by Prof. M. Broca, Paris. (From the Revue Photographique Mars, '72.)......'........220 SC HENTIFIC NOTES So-Called Tobacco Amaurosis—Iostorfer's Syphilis Corpuscles— Changes in the Cord after Amputation................................. 222-225 MEDICAL NEws. Brown-Séquard—Life Insurance Fees—Circumcision in The- ology—The Importation of Opium—A Turkish Medical Journal -Virchow Peripatetic—The Jugulated Colleges—An Oppor- tunity—Medical Senators—Professional Prerequisites—The Promotion of Medioricty................................ * = e s = * * * * * * * * tº a s 4 & a º 225-226 - CORRESPONDENCE Letter from Dr. Reeve—A Point in the Diagnosis of Uterine Polypus,.226 CLINICAL MEMORANDA . Guarana in Sick-Headache—The Condition of the Labyrinth in Cerebro-Spinal Meningitis—Chloral in Venereal Ulcers—The Treatment of Croup—Opacities Tattooed—Treatment of Impo- tence—The Significance of Womiting in Hernia—Cheiroplasty– The Diagnosis of Hysteria.................................................. 226-28 HOME NEWS......,................ • * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * 238 American Medical Association Dr. I * * * * * * * * * =s=== -—º-—-s—s. & The singular cerebral, etc., changes wrought by that štrºnge...condition of the cervical muscles, known as tortigollis (wry-neck), are discussed in full in our chief translation to-day. * . ...Friends to medical progress will be gratified to read 9f the continued and success promising investigations *º the syphilitic corpuscles of the blood. The changes in the cord incident to the destruction of the nerves are of highest scientific interest. # Under clinical memoranda we would call special attention to the notes on sick-headache and on the *gnificance of vomiting in hernia. & ~& 11, No. 19. M A Y 1872, co.,&xº te Co- Fashionable Hatters, IMPORTERS AND MANUFACTUREHS 0F E.ABEES” Eºs, 92 WEST FOURTH ST. Opposite Post Office, * CINCINNATI. ºf Special Inducements to Medical Men- J. TAFT, W. T.A.F.T. Editor Dental Fregister J. & W. TAFT, TIENTISTS 117 WEST FOURTH STREET, CHN CIN NATI, O. The Dental Registers A. Monthly Journal, * Tº e CONTAINING 48 PAGES, Devoted to the Interests of the Dental Profession, List of Pharmaceutical Preparations, MANUIFACTURED BY Jø/ZW WºZAZ & ZººZººZºº, Flººr. Arººrºº’EHCIA- _ºf_h- ELIX. 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These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery I'luid. |M|| ||||||—|| ||M|| PERMANIENT BATTERIEs, For Hospitals and General Practitioners, TEIT IIECTIER, OTDIES. For Eye, Ear, Larynx, Nose, Uterus, Vagina, Bladder, Rec- tum, Feet, Phrenic and Sympathetic Nerves, Elec. trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. —-O->O->=- IEXTRA (TS FROM THE O PINIONS OF THE WroST IEMIN ENT IMEIMB ERS OF THE PIE OFESS / O N. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “Not HING CAN EXCEED THE EFFICIENCY AND CONVENIENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” We are authorized by Prof. Hammond to announce ern- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- proved and re-modified Instruments made by our Company. MEREDITH CLYMER, M. D., Prof. of Diseases of the Neº- vous System and of the Mind, &c., &c.—“I consider their Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prof. of Surgery, St. Louis:—“In neat- ness, compactness and efficacy, they can not be excelled.” ALFRED C. G ARRATT, M. D., Boston :-"In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” Similar Testimonials have been received from JOHN J. CRANE, M. D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A. MURRAY, M. D.; CHAS. E. BLUMENTHAL, M. D.; E. C. SEGUIN, M. D.; ALLEN MAYNARD, M. D., Cleveland, O.; Dr. C. WANNIE, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES KELLY, Florence, O.; Dr. JOHN BECKER, Brighton, Iowa; Dr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes- barre, Pa.; JOIN J. CALDWELL, M. D., Brooklyn, and Ioany other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an Electrical Instrument for medical purposes. IF_A_TIEI, NTT Are furnished to Officers and Soldiers on Government account. tº I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMES A. FOSTEE, 911 Chestnut Street, Philadelphin, Pa. No. 60 West Fourth street. Cincinnati, Ohio, or 172 Jef. ferson Avenue, Detroit, Mich. SAML. P. THOMAS T.A.. I I, OR, IDEALEF IN English, French and Scotch GOODs, 34 West Fourth Street, CALL OR SEND FOR CIRCULAR AND PRICE LIST. ("A.W'6"/.W.W.? 7"A. Wm. Wilson McGrew, JW2. 2% west Aſauºzº srazºr. PIKE's opera House BUILDING, Importer and Dealer * Diamond and Gold Jewelry, watches for Ladies and Gentlemen, Sterling Silver Tableware, Bronzes, Antique and Modern; Marble and Bronze Clocks, Marble Statuary, FAN. cx Coons, G E N E R A L L Y. DIVIDED MEDICINES, —r a’REPARED BY The Divided Medicine Com’y, CINCINNATI, OHIO. The Company have the honor of bringing to the notice of the Profession, this NEW AND ExCEEDINGLY PRAUTICAL METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. The Divided Medicines are prepared by FREDERICK KRAUs, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MORE. * The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, , that in the solidified mass every square will consequently contain accurately measured quantities. But not only SoluBLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINES. * * This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, ; : #. sh, Iº, and even idoo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE TO SPOIL BY ANY LENGTH OF TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calls with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. For samples, Price Lists, and Agencies, address The Divided M. IECXC 2688, Or FRFDERICK KRAUS, Chemist and Druggist, Walnut Hills, Cincinnati, O. MR. FREDERYCK KRAUs: CINCINNATI, February 15, 1871. Dear Sir—The specimens of your “ Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: …” SULPH:MORPHII....................... % grain in each square. ARSEN:ACID.......................... 1-20 grain in each square. “ CH IN INI ....................... 1 & 4 { % ( , CALOMEL % “ • 6 $º $4 COPPER ........................}% {{\ RESPECTFULLY You Bs, g E. S. WAYNE, Analytic Chemist. T TH TET: C T , ITNT I C . 217 S A T U R D A Y, M. A. Y 11, 1872. [No. 19. Vol. 2.] O R. I G IN A L A R T I C L E S. S U R G H C A L C L IN II () . OF PROF. W. W. DAWSON. Good Samaritan Hospital, Castration—Hemorrhoids—Fistula in Ano–Excision of Tonsils, Castration—Indications for the Operation. Reported by Tom. O. Edwards, Jr. The patient presented to you has as you see disease of the right scrotum—it is enlarged, and has on its front aspect a fistulous opening from which exudes purulent matter. A closer inspection shows you that this en- largement is due to hypertrophy of the testicle, and when I make pressure upon the gland there is an in- creased flow of pus. What is the nature of this dis- ease? He has a syphilitic history. Some months after the disappearance of a chancre upon the penis he noticed a change in the right testicle, it was not painful but gave him rather a sensation of weight and uneasiness. it was slightly enlarged and irregular in outline These symptoms gradually and steadily increased, and after a time the mere uneasiness gave place to positive pain; suppuration was soon pronounced. The gland is now enlarged, nodular, irregular in density and dis- charging a thin vicious pus. The history of this man, the course of the disease and the character of the tumor leave but little doubt of the syphilitic nature of the affection. It is difficult to distinguish between a scrofu- lous and syphilitic degeneration of the testicle, so closely are they allied in symptoms and tendencies; true, it may be said that the primary seat of the syphilitic de- Posit is in the testicle, and of the scrofulous in the epididymus and was deferens, yet as the latter so soon involves the gland we are left at last but the history of the patient to guide us. The disease here has not only destroyed the function °f the testicle, but has rendered it an incumbrance, filthy and unendurable. Medicine is powerless, Con- *Vative surgery is worse than useless. Castration is * only justifiable remedy; it is an operation easily performed and unattended with danger. I make, as you see, an incision over the front of the gland, first rendering the skin tense by grasping the tumor from behind; a few touches with the knife expose the testicle and the cord. You may tie the cord in mass or isolate its vessels and apply ligatures to them. Your incision should extend well up towards the external ring that you may have the cord completely in hand. As the repair here is by granulation, sutures are not generally used, but in this case I propose to try the effect of carbolic acid in preventing suppuration and in promoting an early union. I wash the wound with a solution of equal parts of carbolic acid and water, and bring the edges together by a few interrupted sutures. Castration is such an abridgement of a man that it should not be resorted to until all other means have been fairly and faithfully tried, and here in connection with this case I may briefly enumerate the conditions which indicate the operation : 1st. Syphilitic disease, not where you have one or both testicles involved in constitutional syphilis by a mere | deposit of fibrinous matter in the connective tissue, but where, like in this man before you, the degeneration of the gland by the specific infection is complete, render- ing its longer stay not only useless, but damaging to the general health. 2nd. Scrofulous degeneration, those cases in which sup- puration has destroyed the function of the organ. 3rd. Malignant disease, this when attacking the testicle is usually of an encephaloid character. After you have decided that the case is malignant, do not delay the op- eration until the neighboring glands are involved, for then your efforts will be as unsatisfactory as in other regions where interference is postponed until the disease is no longer local. The knife in malignant disease is but poorly successful at best, the earlier however you resort to it the more promising will be the prospects of your patient. 4th. Non-malignat tumors of the testicle, cystic, fibrous, fibro-cystic, enchondroma. In these non-malignant affec- tions of the testicle, castration should only be resorted to when the tumor interferes with health, comfort or con- venience. Hemorrhoids, The patient before you has a large hemorrhoidal tumor at the verge of the anus—it may be called a mixed pile—partly external and partly internal. For internal piles the ligature is used; external piles are re- moved by the knife, but what is the proper treatment of a case like this, involving or rather partaking of the nature of both ? The ligature is advisable in this case, for here, as in internal piles, hemorrhage is liable to occur, and if it should, it would be difficult to manage. I take as you see a needle armed with a long and strong ligature, and after transfixing the tumor, strangulate its two divisions. Remember these two points; you must have your ligatures long enough to be wound around each 218 [MAY 11, 1872. T THE EIB C T , I INT I.C. hand and strong enough to allow of sufficient force to strangulate the tumor completely. Fºstula in Ano with Easternal Piles. You see in this man a fistulous opening about one inch from the anus. The anus is surrounded by small external hemorrhoids. In examining this case I find a sinus extending downward and towards the rectum—it reaches to, but does not enter the bowel. This is what is known in your books as incomplete fistula; it is the sequela generally of ischio-rectal abscess. What is the treatment 7 The division of the sphincter is the only remedy. You may apply lotions, caustics, and stimulat- ing injections to such a case for weeks and months with- out avail—the constant contraction of the anal sphincter thwarts you. In operating you convert this incomplete into a complete fistula. I insert into the anus a piece of soft wood—then introduce a grooved director through the sinus down to the rectum, along this groove I pass a narrow bladed knife and thrust it through the rectum into the piece of wood—the withdrawal of both divides the sphincter. The wound should be dressed with dry lint. After thus dividing the sphincter I excise as you see with these scissors the external hemorrhoids. The scissors should be blunt pointed and curved on the flat surface. Eaccision of Tonsils. This little patient, between two and three years of age, has enlarged tonsils—with this exception the child presents every appearance of vigorous health. The hypertrophy of the tonsils is very great—the glands almost meet in the median line, and whilst the general health is not compromised, the presence of these large bodies seriously interferes with the comfort of the child. The hypertrophy of the tonsil is a kind of fibroid degen- eration, the soft and delicate structure of the gland is replaced by a deposit of more consistence, and through this mass bands of fibrous materal interlace. A few years ago it was the fashion to remove tonsils—then the operation was performed scores of times where it is now resorted to once—however slight the enlargement, the knife was applied. No good but much evil followed this liberal sacrifice of tonsils. A better surgery now prevails. Where the enlargement is not so great as to embarrass deglutition or respiration, the surgeon should not interfere, but where, as in this case, the diseased glands so encroach upon the isthmus of the fauces as to amount to a positive obstruction, they should be excised. º The operation may be performed by seizing the tonsil with the vulsellum forceps and dividing it with a curved bistoury. I use to-day the guillotine. I depress the tongue—place the instrument over the tonsil, trans- fix the gland with a needle and by withdrawing the concealed knife the operation is concluded. I PROGRESSIVE IN ITUSCULAR ATROIP H (Y. BY WM. CARSON, M. D. The History of and Remarks upon the Case of a Patient presented to the Academy of Medicine, April 29, '72. Morris O'Donnell, aet. 69, Ireland, widower, laborer. Father died of an injury caused by lifting a weight. Cause of death of mother and two brothers unknown. One sister living and two dead of old age. Has been a drinker during his life. Never had syphilis. Has had measles, small-pox and remittent fever. States that he took sick in September last with a pain in both shoulders and arms, which came on after having exposed himself by hard work, mowing grass and sleep- ing outdoors on the new mown hay. After this, during the winter, his fingers and hands became crippled, and he felt a general weakness all over his body. Present Condition. Of average frame, gray hair and beard, and wrinkled condition of face. Skin warm and moist. Flabby condition of muscles of arms, but no pain. Flattening of ball of thumb of right hand and also between thumb and first finger. Interosseous spaces deepened. Forearm flattened, skin over outer side loose. Circumference just above wrist 6 inches; middle of forearm 7 inches; below elbow 7 and 7–8th inches; lower end of humerus 7% inches, with elbow bent 8 inches over biceps; 84 inches at margin of axilla. Biceps not apparent on bending the elbow, flattening about the shoulder, acromion process well marked, flat- tening and wasting of scapular muscles; palm of hand and flexor muscles not so much atrophied. Left arm above wrist 6 inches; middle of forearm 6% inches; upper part just below elbow 7% inches; lower end of humerus with arm extended 7 inches; flexed 7% inches; at margin of axilla 8 inches. Some flattening of shoulder and posterior aspect of joint; acromion pro- cess prominent; abduction and adduction of thumb imperfectly performed. First three fingers can not be straightened from contractions of tendons of the atro- phied muscles. The skin over 2nd–3d phalanges very smooth. Dynamometer moved by right hand to 10° on the outside scale, and to 22° by the left hand. Pain about attachment of occipital muscles. Tactile sensibility on left side greater than on right; no sensations of pain, or needles, etc., in arms or legs. Electric con- tractility imperfect. Fibrillar movement apparent over upper part of body. Skin over pectoral muscles and over abdomen hanging very loose. Good muscular movement over frontal portion of head; facial muscles and their move. ments on both sides about the same. In the effort of throwing shoulders back, the right shoulder moves better than the left. Puts his right hand on top of his MAY 11, 1872.] TIE-L ED CT I I INTI C . 219 ºs-— head awkwardly, but unable to do the same act with his left hand. Tongue coated with a yellowish fur; de- flected to the left. Pulse 78 and tolerably full. Arteries more or less degenerated. Appetite good. Bowels in- clined to be costive. With no expectation of arrest or improvement of his disease, we have ordered the appli- cation of the constant current to the spinal column and the interrupted current to the muscles. The recent in- vestigations of Charcot and Hayem” into the morbid anatomy of this disease though interesting do not offer any more encouragement as to the therapeutical control of it. They believe that the essential origin of it is in atrophy and destruction of certain cells in the gray matter of the anterior cornua of the spinal column. It is probable that the degeneration in this case extends high up, as is evident from the deflected tongue which shows some paralysis of that organ. —-º-º-º-º- A C A D E M I Y O F M E D 1 c 1 N E. *-*-* JAS. GRAHAM, M. D., PREST., L. WOLF, M. D., SECTY. Transactions May 6, 1872. Reported by Joseph Ransohoff. *-sº Correctºons. DR. WALKER corrects the report of his case as one of confluent small-pox after vaccination as follows: “The case referred to was to show the effect of vac- cinia as a protective agency. Also as an exhibition of “Royce's test,” and to offer any one the opportunity who wished to try vaccine virus taken from a patient who had the eruption of varioloid at the same time with the vaccine pustule. The first child, aged 3 years, died of confluent small-pox: the father having refused to have it vaccinated for fear of injurious effects. The Second child I vaccinated on the second day of eruption of the first, and I again vaccinated it on the other arm three days later. The ninth day of the first vaccination the little girl aged 13 years had a slight eruption of Varioloid, though distinctly marked.” Yours, J. P. Walker. DR. THORNTON, according to a request made by DR. CoMEGYs, stated that the remarks made by the latter ºn the previous evening were misapprehended. Judg- ing from the report in The Clinic, it would be thought that Dr. Comegys would treat all his cases of cerebro- spinal meningitis by the use of morphia hypodermically, which was a misconception of his views. The Dr. Would treat only the most severe cases of this disease in the manner Specified in his remarks on that occasion. Cerebro-Spinal Meningitis. PR. THORNTON reported two cases of cerebro-spinal *— *Archives de Physiologie, 1869, vol. 2. ' meningitis. He saw both for the first time Friday, April 26th. The first case was that of a child aet. 2 yr. It had been seized by a convulsion on the night pre- ceding the first visit. On the following day it was attacked by severe vomiting, spells of which alternated with convulsions. The head was thrown back, but the muscles were not rigid. The temperature in this case varied from 100°–1003°. Pulse 100. Applied one leech behind each ear, which seemed to prevent the recurrence of the convulsive paroxysms. Ordered a mercurial purge, which was followed by potass, iodidum. Also applied ice bags to the posterior part of the head and neck. Under this treatment the patient was apparently improving, being quite conscious, and the intellect re- maining unimpaired. Convalescence was apparent until yesterday (May 5th), when the child was again seized by a convulsion. To-day both pupils were dilated, and the patient was in a semi-conscious condi- tion. No petechiae present. The second case was that of a girl aet. 6 yr. Some of the family having had in- termittent fever, the disease was supposed to be of malarial complication, and was treated accordingly, The patient however, soon complained of severe headache, and extreme tenderness in the posterior part of the head. There was also some rigidity of the muscles of the neck. As in the first case, ordered a mercurial purge and applied leeches (4), and ice bags to the head. An apparent improvement was manifest until last Sat- urday night when the severity of the symptoms increased. She complained of severe headache, and there was a decided tendency to opisthotonos. No petechiae were observed. Prognosis unfavorable. Ordered quin. Sulph. and potas, iod., and ice bags to the head and neck. DR. REAMY presented a specimen which was removed from a patient under the care of a medical friend. The patient was a robust man aet. 21.-April 26. Found him in a stupid and delirious condition from which he was with difficulty roused. Complained of intense cephalalgia and unquenchable thirst. Opisthotonos well marked. There was manifestly a partial paralysis of the lower extremities. The pupils were dilated and insensible to light. Respirations 48, pulse 50 per minute. Great irritability of the stomach and obstinate constipa- tion. Cold clammy perspiration covered the body and petechiae were visible. Ordered ol, tiglii gtt, ss, every hour until an operation from the bowels was procured. Ordered also quin. sulph. gr. iij, and hydrarg. chlor, mit. gr. j. every three hours. Several hours later applied a cantharidal plaster to abdomen, continuing the ol. tiglii and administering full doses of bromide of potassium. April 27. Vomiting ceased and other symptoms indi- cate an improvement. Body warm and perspiration profuse. Respirations 40, pulse 80. One stool. Blister effectual. Continued full doses of bromide of potassium and citrate of magnesia. 5 P.M. symptoms worse. No stool. Resumed ol. tiglii and ordered beef tea. April 28. No stool and no further vomiting. Respi; rations 48, pulse 140. Pupils contracted; skin dry and hot. Delirium greatly increased. 220 [MAY 11, 1872 TiEEE C I.I. NI c. April 29. The symptoms being the same as those of the previous day, the same treatment was continued. April 30. The patient died having had increased de- lirium up to within five minutes of death. Dr. Reamy called the attention of the Academy to the great discrepancy between the pulse rate and the frequency of the respiration; as to the accuracy of the observations ther could be no question. He then pre- sented the cerebellum and the superior portion of the spinal cord. A superficial congestion was everywhere noticeable. The anterior subarachnoid space and the fourth ventricle contained a considerable quantity of a muco-purulent deposit. The vessels of the pia-mater were also deeply congested. The meninges of the brain were injected while those of the spinal cord presented a normal condition. The substance of the brain and cord was normal. DR. MUSCROFT spoke of two cases which had occurred in his practice, the symptoms of which closely resembled those of cerebro-spinal meningitis. He then spoke of the various and different pathological conditions found in different cases. —-º-º-º- Tortroom.Lis. Clinical Lectures Delivered at “Ila Pitie” Hospital Jan. 8–10, 1872. BY Prof. M. BROCA (Paris). From the Revue Photographique des Hôpitaux de Paris, Mar., '72. GENTLEMEN: The patient in bed 18, St. Louis ward, is affected with torticollis of long standing, the commencement of the disease dating back to the time when he was 10 years old, he being to-day in his 31st year. As surgery can in this case interfere beneficially, notwithstanding the long continuance of the deformity, I think it an opportunity of establishing in your presence with all possible certainty the diagnosis of this deformity. You know that torticollis may be primarily osseous or muscular. In case of disease of the vertebrae, the osseous levers being at the outset altered, the equilibrium of the forces that move these levers is destroyed. From the vicious position of the bony framework there results a disturb- ance of the muscular force. The muscle whose function is impaired soon loses its proper structure; at first pale and diminished in size, it finally undergoes granulo- fatty degeneration. I will not enumerate to you the various diseases of the vertebral column that may give rise to these disorders, rheumatic arthritis, scrofulous abscesses, etc. At other times the origin of the de- formity is in the muscle itself or the nerve distributed to it; and in the latter case there may be an excess or deficiency of nervous action. Consequently we have two species of muscular deformities—the direct, by con- traction, the antagonistic, by paralysis. The diagnosis between the two is easily made. In the case of our patient there is evidently no paralysis. The head is turned to the left, the right sterno-mastoid is healthy, the patient can contract it and slightly carry the head to the right side, although this movement is very limited. The same result can be obtained by the application of electricity. I would call your attention in this connec- tion to a good characteristic of torticollis by paralysis; the patient cannot bring the head straight; the surgeon on the contrary, can easily bring it to its normal posi- tion, so long as consecutive contracture of the muscle of the sound side has not fixed the head in its abnormal position. We have then in the man under observation a torticollis by contraction. But what is the cause of this contraction ? We shall find it in the muscle itself or in the central nervous system. Is it in the nervous system 7 . It is most often in children during the pro- gress of a disease accompanied by convulsions, meningitis for example, that torticollis of nervous origin is devel- oped. Is it in the muscle? We shall upon this hypo- thesis have to do with a rheumatic affection developed in adult life. I should here remark to you that in my opinion the muscular pains called rheumatic are with- out doubt accompanied by a tissue lesion, which is noth- ing else than a very slight degree of inflammation; that on the one hand produces the functional phenomena with which you are familiar, (vicious position in torticollis and muscular coxalgia), on the other hand diminishes the resistance of the fibres and causes ruptures such as have been observed in lumbago. The rheumatic affection of a muscle may last suffi- ciently long to cause in its tissue a disturbance of nutrition. The elements that compose it, fibres, con- nective tissue, sheath, then shorten themselves. The neighboring muscles that are nourished in a vicious po- sition equally become shortened; the same is true of tle ligaments; the bones themselves become deformed by the settling together of their molecules. And if the deformity dates from infancy it may attain an extreme degree, for growth takes place freely on the convex side, while it is impeded on the concave side. The patient who is in our ward has probably had in infancy a febrile affection with convulsions. We put aside muscular rheumatism as much less probable, on account of the age at which the disease commenced. For you know that in children muscular is infinitely less frequent than articular rheumatism. But before stating our diagnosis in an absolute manner, let us say that a pri- mary osseous affection appears to us very improbable. The deformity of the skeleton is considerable it is true. The vertebral column is convex to the right in the cer- vical region, and to the left in the dorsal region (com- pensatory curvature). But this deviation of the column is not necessarily primary, it is the natural consequence of the deviation of the head. Moreover if I examine MAY 11, 1872.] TIEEE CI.IISTI c. 221 the patient attentively Isee that the sterno-mastoid is the only agent that I can fix upon as at fault. When an osseous deformity produces consecutive muscular retraction this does not affect solely the sterno-mastoid. The neighboring muscles are deformed also, and contribute to the maintaining of the vicious position. Here the sterno-mastoid alone sets its seal upon the deviation. A torticollis which has not this muscle for its producer may be even more exaggerated, but has not this form. We conclude then that our patient is affected with muscular torticollis by contraction of the sterno-mastoid. Now what is to be done? The indication for tenotomy here naturally presents itself. I may say to you to begin with, that the section of the inferior attachments of the sterno-mastoid is one of the most benign opera- tions of surgery. But what shall we gain by this opera- tion? The first obstacle that presents itself to us is the sterno-mastoid with its two inferior insertions. But is this the only one 7 When the section has been made will the other muscles that have for a long time been accommodating themselves to the deformity be more yielding than the sterno-mastoid 2 And the ligaments? And the bones especially? Shall we be able by mechanical means to overcome their resistance? To sum up gentlemen, in making the tenotomy we shall perform a harmless operation certainly. Shall we ob- tain an amelioration ? Yes without doubt. Shall we entirely correct this deformity? I expect not. Never- theless we shall proceed to divide the muscle, and by the aid of an orthopaedic apparatus we shall oppose as best we may the other obstacles. GENTLEMEN: The operation that we made day before yesterday upon our patient with torticollis, has given an immedi- ate result much more favorable than I anticipated. The head as you saw straightened itself almost com- pletely after section of the sterno-mastoid. Although the head and face are still deformed as they should be, (and I shall directly call your attention to this fact), we are permitted to hope that the deformity will be better corrected than we hoped at the outset. I will re- mind you also, that immediately after the operation and the straightening of the head, the patient was seized with clonic convulsions which lasted only a few minutes, and which presented to us the spectacle of a genuine attack of hysteria. At the first, seeing the number of inspirations suddenly doubled, I thought of the phrenic nerve and asked myself at the moment if my tenotome could have touched it. But this thing was very little probable, and the true nature of the passing convulsions could not long remain doubtful. The patient is nervous, cowardly and his intellect is but little developed The emotion caused in him by the oper- ation and the sudden change of position of the head, gave us a sufficient explanation of the phenomena we had observed. There remains now under the skin a tendon-like cord occupying the place of the clavicular attachments of the sterno-mastoid, which gives the idea that we did not divide the entire thickness of the fibres at this level. Nevertheless, and this is the essen- tial thing, the head is completely free, and the presence of this cord does not prevent our inclining it over upon the shoulder of the opposite side. I do not think that the Section of this fibrous band will later become neces- sary. We have covered the little wound made by the tenotome with a piece of diachylon plaster. It is not needful to say to you that it will not suppurate. We shall apply the apparatus that you have known under the name of minerva. I have now to say a few words to you respecting certain physiological phenomena pro- duced by this torticollis. There has resulted from the faulty position a profound change in the nutrition and development of the head. You can observe without difficulty the inequality in the two halves of the face. This is a well known result of torticollis, especially of that dating from childhood; it may be produced nevertheless, although in a less degree, by torticollis de- veloped in adult life. Notice carefully the patient; the nose is not vertical, the line of the eyebrows is not horizontal. The angle of the jaw on the affected side is much more approximated to the eyebrow than that of the sound side. And that you may not be deceived, compare the direction of the superciliary line with that of the other transverse diameters of the face; you will see that when the head is not kept in place by the ap- paratus all are deviated in consequence of the vicious inclination, but that the obliquity of the Superciliary line notably exceeds that of the other diameters. But it is not the face only that has been affected by the deformity. A priori the cranium ought to participate; and this is in fact what does take place although authors do not speak of it. I have had the scalp shaved and there is apparent a notable deformity of the cranium. The left parietal eminence is sensibly less convex than the right. You can without difficulty recognize this inequality upon the cast that I had made by M. Stahl, and which will be deposited in the anthropological section of the museum. The brain and organs of sense ought to have suffered with the cranium. Let us continue then our examination with reference to this point. The patient has little intelligence, is whimsical and hysterical, as I have already said to you. His body is but slightly developed, his height not ex- ceeding 5 feet. This ought not to astonish us for we cannot deny the influence of the brain upon the devel- opment of the entire organism. The microcephalics re- main small; all true dwarfs are microcephalous. We have tested with the dynamometer the condition of the muscles. Here again we obtain results worthy of atten- tion; the left side at each examination is not shown to be feebler than the right; oftentimes the difference is nothing; generally the right side is shown to be feebler by several kilogrammes, and yet the patient is not left- handed. You see then that in this man it is the right half of the brain that predominates, while in the normal condition it is the left half that overpowers the other, 222 [MAY 11, t&72. TIEEL H. C. T.I. NT I. C. not only in man but in birds which as you know almost always perch on the right foot. This relative feebleness of the left half of the brain in our patient is well in ac- cordance with the atrophy of that half of the head, The examination of the organs of sense shows that one eye is not as good as the other; and the same with regard to the ears. But this time it is on the side corresponding to the torticollis that the impairment is found. And this result is just as readily explained as the preceding. The eye in fact is under the control of the two hemispheres, but especially of the corresponding one. The ear evidently is dependent upon the corresponding hemisphere; for there is no chiasm of the auditory nerves. Lastly, gen- tlemen, we tested the cutaneous sensibility. But here we obtained only contradictory results, thanks to the patient's lack of intelligence. I hear the name of Bichat whispered. Bichat had the cranial sutures displaced, but do not doubt, gentlemen, that the two halves of his brain were equal. The cranium and the brain are it is true correlative in their development, but independent nevertheless within certain limits, and if they are not reciprocally under restraint, the one may in certain re- spects be irregularly developed without the other ceasing to be properly developed. By what mechanism can a torticollis give rise to these anomalies of develop- ment? The head, say some is inclined to the ground while it was intended to look upward. Os homini sublime dedit; and this explanation satisfies them. Too poetical for us, it does not come within the domain of science. We must seek for a more tangible cause, one especially that will account to us for the whole aggregation of phenomena, a mechanism appli- cable to the whole head. We shall find it in the arterial system. The exaggerated curvature of the carotid, the result of the faulty position, increases the friction of the blood against the vessel-walls; and diminishes the force of the circulation in the entire half of the head. Doubtless the carotid of the sound side undergoes an increase of curvature but this deviation is much less considerable, and does not occasion anything like the same circu- latory disturbance. Such is, gentlemen, the most rational mechanism that we can suggest to explain the phenomena of atrophy resulting from torticollis. §CIENTIFIC NOTES. SO-CALLED TOBACCO AMAUROSIS.–The last series of Jonathan Hutchinson's cases of tobacco amaurosis has just appeared. They embrace those cases that have come under his observation from '67 to ’70. Mr. Hutchinson has already published two series, but this last has been more carefully analyzed. The first series contained 37 men and 3 women, the second contained 34 men and 5 women, the third con- tained 28 men and 1 women. It will be seen, the author remarks, that there is a general disproportion between the two sexes, indicated in each series, thus the last two confirm in a striking manner the conclusions of the first. . The author believes that we have to do with a “formidable type of symmetrical amaurosis which is almost exclusively confined to the male sex.” The author refers to an interesting fact of a mother, son and nephew all having the same form of amaurosis, and adds, “the lesion of these facts seems to me to Sup- port the opinion I have long held, that when tobacco causes blindness it does so in virtue of an idiosyncracy. It is by no means improbable that such idiosyncracy will be found occasionally in several members of the same family, and further that it may involve liability to suffer from other influences besides tobacco Smoking. The two cousins above alluded to were affected with amaurosis by virtue of an idiosyncracy rendering them liable to special poisoning by tobacco; the mother (and aunt) who never smoked was the subject of a similar form of nerve disorder by virtue of the same diathesis, acted upon by a different excitiug cause, probably the cessation of menstruation. Not unfrequently has the author found that these patients have learned to smoke with difficulty, and have always displayed unusual susceptibility to its influence and have been more than ordinarily liable to suffer from Sea-sickness. Shag, in the authors opinion is the most deleterious form of tobacco. Cessation of the habit of smoking almost invariably allows the vision to improve. No case seen early and when the patient has ceased smoking entirely has gone on to blindness. —l-e-e—º- Lostorfer's Syphilis CorpuscIes. Letter from PROF. FREEMAN J. BUMSrPAD, M. D. From the N. Y. Med. Record, May 2, "72. VIENNA, APRIL 5, 1872. MY DEAR DOCTOR,-Before this reaches you I pre- sume you will have received and published a letter from my friend Dr. Bronson, with regard to the so-called “syphilitic corpuscles,” which Dr. Lostorfer claims to have discovered in syphilitic blood, and which as he asserts, are an unfailing sign of syphilitic infection. With this letter already before your readers, it is an- necessary for me to describe the method of examination adopted by Dr. Lostorfer, nor to speak of the excite- ment which ensned upon the announcement of the dis- covery in the K. K. Gesellschaft in Wien, nor of the violent or personal character of the discussion which has since followed among the disputants pro and con. ; MAY 11, 1872.] TIEEI IEH C T I I INTI C. 223 but I hear that the subject has excited quite as much, if not more, interest in America than here, and your readers may like to know the further progress of the matter in Vienna. Dr. Lostorfer's investigations were commenced in |. Prof. Stricker's laboratory, aud Prof. S., after subjecting Dr. L. to the successful test of an examination of a number of specimens from syphilitic and non-syphilitic persons, gave his permission to Dr. L. for the publica- tion of the latter's paper. In the discussion which en- sued, the chief opponent of Dr L.’s views was Prof. Wedl, who asserted that the “corpuscles” were only fat, or particles of protoplasma, which had accidently gained entrance into the blood at the time it was drawn. Prof. Wedl also severely criticised Dr. Lostorfer's method of examination, and was himself as severely criticised by Prof. Stricker in return. Profs. Gruber and Neumann took sides with Prof. Wedl; while Prof. Hebra, and especially Prof. Stricker, have stood up for Dr. Lostorfer to this extent, that he was successful in recognizing syphilitic from non-syphi- litic bloodin a certain number of tests to which he was subjected; and Prof. Stricker was induced, if not com- pelled, both by the scientific interest of the subject itself and by the personal manner in which he had been attacked, to follow out a series of investigations for himself. Prof. S. kindly invited me to witness what he was doing, telling me at the same time that his object was not so much to settle the question of the dependence of the corpuscles exclusively upon syphilitic infection, as to ascertain the best method for their examina- tion, and the manner of their growth, so that others might be better prepared to carry on the investigation as to their origin; and I propose chiefly to relate what he has thus far accomplished. The first time I visited Prof. S.’s laboratory I found the temperature of the room raised to an uncomfortable degree of heat, and was told that this was done ex- pressly in order to hasten the appearance and favor the growth of “the corpuscles.” A few days before, the fire had been allowed to go out, and the corpuscles were very slow in making their appearance, and in their subsequent development. Prof. S. has since accomplished the same object by using the warming apparatus [heitzbarer Objecträger] invented by him, and described in the introduction to his Handbuch der microscopischen Anatomie, p. 14, or again by setting the moist chamber, in which the speci- mens are kept when not undergoing examination, in the sun, which at this season of the year is not too warm. Of course the former mode is emyloyed when it is desired to keep the same specimen under the microscope for any length of time, and watch it every few minutes; and the mercury in the thermometer attached to the apparatus should indicate twenty-nine degrees of Celsius, when the temperature of the glass slide is supposed to be about twenty-four or twenty- * five. A greater degree of heat is injurious; for exam- ple, yesterday the mercury was allowed to rise to thirty-five degrees of Celsius, when the corpuscles en- tirely disappeared. In order to keep the air moist around the specimen, and prevent the evaporation of the fluid contents, four folded pieces of bibulous paper are thoroughly wet and laid one on each of the four sides of the object glass. Care must be taken that the water does not flow over the glass to the specimen, and, on the other hand, the wads must be moistened as fast as they become dry. At the time of collecting the specimen of blood, it is desirable to lay two exceedingly fine shreds of silk across it (parallel). These serve a double purpose; that of collecting a portion of the plasma of the blood, and that of serving as landmarks by which the position of any single corpuscle or set of corpuscles can be fixed in the memory, or by the aid of a drawing, from one examination to another. The ends of the slide should also be marked right hand and left. Prof. Stricker has found one difficulty attending the preservation of the slides in the moist chamber, viz.: the vapor collects to some extent upon the glass, and a small, but still an appreciable, amount of water gains entrance beneath the covering glass, and this, as I shall presently mention, has an injurious effect upon the corpuscles when young, causing them, if the amount of fluid be sufficient, to shrink. Thus far, how- ever, the moist chamber cannot be dispensed with. Prof. Stricker is trying to find some way to obviate the difficulty, and meanwhile recommends that the slides, after being charged with blood, should be ex- posed to the air long enough to allow a narrow rim of the specimen to dry, before they are placed in the chamber. With regard to the magnifying power requisite for the examination, I presume Dr. Bronson’s paper in- formed you. Prof. S. uses, as Dr. Lostorfer did, Hart- nack’s immersion lens No. 10, and occulaire No. 3. The corpuscles first make their appearance towards the periphery of the specimen, or in the neighbor- hood of an air-bubble, in other words, towards the part nearest the external air. This would show either that their germs are derived from the air, or, more prob- ably, that the air is more favorable to their develop- ment. The first morning that I witnessed Prof. Stricker's examinations, some blood was under the microscope, which had been drawn only twenty minutes before. Blood from the same patient had previously been tested and found to be unusually rich in corpuscles. At my entrance Prof. S. told me he thought he could see the commencement of corpuscles, but was not certain. I looked in and, on moving the fine adjust- ment, could see a number of exceedingly minute points, of a dark color, scattered over the field. While I Was Watching them, one of these points gradually 224 [MAY 11, 1872. TIH. H. cI, IISTI c. increased in size, and assumed the light-breaking ap- pearance of a corpuscle, with which I was already familiar. In the course of half an hour, five or six were to be seen, and after the lapse of another hour there were twenty to thirty in the field, and several of them had attained four or five times the diameter they had at first. I must repeat, however, that this degree or rapidity in the time of appearing and in growth is extremely rare, and, as Prof. S. remarked, may not be met with again in a long period. To one who has carefully studied these bodies it makes but little difference whether their growth takes place in a few days or in a few hours; but such a case as this af- fords an admirable opportunity for demonstrating the fact to others. With regard to the sprouting of the corpuscles de- scribed by Dr. Lostorfer, Professor S. has observed nothing more than what appeared to be a ripe-like projection on the side of one of the larger corpuscles [this too, if I am not mistaken, is all that Dr. Bronson ever observed], and he is not certain that this is a sprout, because he has repeatedly seen a small corpuscle come in contact with a larger one, and subsequently in ap- pearance coalesce with it. - The addition of water or of acetic acid causes the younger corpuscles to shrink and shrivel up, but has little or no effect upon the older ones. Iodine also causes them to shrivel, but does not change their color to blue. . Osmic acid does not turn them black, and hence they cannot be fat, as Prof. Wedl asserts. Prof. Stricker is not prepared to state positively what the nature of these bodies is, but he regards them as, probably, organisms, and judging from the action of reagents upon them, not of a vegetable character. Prof. Stricker has examined the blood from many cases of healthy persons, from five cases of lupus, from five cases of variola, from three cases of typhus, and from one case of typhus abdominalis, and in none of these was he able to discover the bodies in question, except in one case of lupus, in which they existed to perfection; but here the question comes in, whether lupus is a form of spyhilis or not. The number of syphilitic persons whose blood he has thus far examined is twelve; in nine he found these bodies and in three he did not; but he is not sure that their apparent absence in the latter was not due to de- fective examination. - I have also had several opportunities of conversing with Dr. Lostorfer. He has told me, what I had heard from several other sources, that he had been making a special study of the blood a long time before he hit upon his supposed discovery. The first time that he happen- ed to examine the blood of a syphilitic person he recog- nized these bodies as something which he had never seen before. Regarding them as doubtless due to syphi- litic infection, he has now abandoned the study of healthy blood. blood will resemble a syphilitic corpuscle. I asked him if there was nothing in healthy blood which could be mistaken for them. He replied, “Yes, to an inexperienced observer,” and that even the most experienced observer, if allowed only a single examina- tion, might, in some instances, be in doubt, but that this doubt would be removed by repeated inspections of the specimen. - ... • The most liable sources of error are the following: Sometimes a nucleus of a colorless corpuscle of healthy Usually a fine outline, at least, of its cell-wall may be seen and will show what it is. But even if it be separated from its cell and stand alone, it does not so sharply break the light as a syphilitic corpuscle, and its outline is broader and darker. - Fragments of torn red corpuscles may also give rise to deception, but they show no tendency to increase of size and soon disappear. In this statement, I presume Dr Lostorfer took it for granted that no one would mistake an undeveloped red corpuscle for one of these bodies, for this error certainly might occur to a novice. I would also add that both Dr. L. and Prof. Stricker evidently attach much import- ance to a prolonged or repeated examination of the same specimen, by which the conduct, whether pro- gressive or retrograde, of suspected bodies can be ascer- tained. - I am not aware that the opponents of Dr. Lostorfer are carrying on any serious investigations to demonstrate their fallacy, if such exist. They appear to be satisfied with the assertion that his corpuscles can be found in any blood, and that they are fat or protoplasma, or something else, but not an evidence of syphilis. The controversy has unfortunately assumed a personal char- acter, and I hear the words, “unloyal,” “swindel,” “ass,” and (without fear of wounding an American's feelings), “Barnum-humbug,” oftener than is either dignified or gentlemanly. I have no idea that the question is to be settled in a hurry; and, perhaps, I shall have a chance to write you of its further progress during my stay here. . I cannot close without a few words in justice to Prof. Salisbury, of Cleveland, Ohio, who published his paper on the “crypta syphilicica,” and “crypta gonorrhoica,” in 1868, a copy of which, I am sorry to say, I have not been able to find in Vienna for reference. Within a short time of its publication, Prof. Salis- bury was so kind as to send me some blood which he said contained the syphilitic crypta upon a slide: and my impression is that the bodies were very similar to those that I, now see in Vienna, but I cannot be positive, after so long a time, that they had the same essential characters. With the aid of the able microscopist, Dr. Ed. Curtis, I examined the blood from a number of syphilitic atients in my wards at Blackwell's Island, and we ound the same bodies as in the specimen sent by Prof. Salisbury, but we also found what appeared to be the same in the blood of several healthy persons. * MAY. 11, 1872.] Now the bodies that Dr. Curtis and myself saw were to be seen in the blood immediately after it was drawn from the body; and, if I am not mistaken, Prof. Salisbury insisted that they should be sought for at this time; whereas the corpuscles of Dr. Lostorfer are rarely to be seen (except in some extraordinary instance as the one I have mentioned, or except when hastened by heat), until after the lapse of at least twenty-four hours. - For this and other reasons I do not feel at all sure that Prof. Salisbury’s “crypta” and Dr. Löstorfer's cor- puscles are one and the same thing; but should this prove to be the case, the honor of priority in this dis- covery will undoubtedly belong to Prof. Salisbury, and no American will more heartily rejoice at it than - Yours very truly, F. J. BUMSTEAD. Changes produced in the Spinal Cord after Ampu- tation of a Limb or section of the Nerves of the Limb. BY M. VULPIAN. The amputation of a part or the whole of a limb in man causes remarkable changes in that portion of the spinal cord which furnishes the nerves supplied to the part which has been amputated. These modifications consist essentially in a general diminution of the size of the corresponding half of the cord in that region. Con- trary to what I had noticed in the earlier cases that I examined, and in accordance with what Dickinson has indicated, it is the posterior part of the cord, that is to say the posterior horns and the posterior column, that in the greatest degree undergoes these changes. This diminution in every respect of the dimensions of the modified parts is not due to any actual alteration of structure; there is no interstitial myelitis nor granulo- fatty atrophy of the constituent elements of the cord. In certain cases, although exceptional, the interstitial tissue of the altered posterior column is a little hyper- trophied. Perhaps in these cases there had been for a long time violent pain in the stump. As a general rule, there is produced simple atrophy, that is to say, a re- duction of the diameter of the elements, principally the nerve-tubules. The changes in the spinal cord follow- ing amputations, have been observed not only when the amputation was made before the period of cessation of body-growth, but also when made in adult life, and even in the senile period. They are, however, the more rapid and more strongly marked as the age is less ad- vanced. In order that very manifest changes shall have taken place in the case of adults, there must have elapsed an interval of Several months at least between the time of operation and that of death. It may be asked if the TIH. H. C.I.I.INI c. that observed in man after amputations. 225 local atrophy of the spinal cord in these cases of ampu- tation is due chiefly to the section of nerves in the opera- tion. To clear up this point, the nerves of a limb must be divided by themselves, the other parts being duly preserved. I have made a section of the great sciatic on one side, and sometimes also of the crural on the same side, in a number of animals (dogs, rabbits, Guinea-pigs). After varying intervals of time I have examined the dorsal and lumbar regions of the cord in these animals. Two or three months after the operation and even after thirty-six days in young rabbits, I have observed an atrophy of the corresponding half of the cord in the region in relation with the roots of the divided nerves, and this atrophy presents the same characteristics as It is then principally if not solely in consequence of the section of the nerves of an amputated limb that local atrophy of the corresponding half of the spinal cord takes place. |—Arch. Gen., April, '72. —º-e—sºm- M IELDICAL NEWS Dr. BROWN-SEQUARD.—Dr. C. E. Brown-Sequard, who has been on a short visit to this country, will soon return to France. He remains abroad until September, when he will return to give his course of lectures at the Harvard Medical School. He gave a characteristic lecture on brain diseases before the Medical Library and Journal Association on the evening of April 12th, to a large and appreciative audience.—N. Y. Med. Rec. May 2, 272. LIFE INS. FEES.—The Canada Lancet, in speaking of the fees for life insurance, says that the fee differs with the amount insured, from $2.50 to $5.00. In London, twenty-five years ago, it was decided that the companies should, in all such cases, pay a uniform fee of one guinea. CIRCUMCISION IN THEOLOGY..—Peritomy, (Circum- cision) was made an obligatory study in the rabbinical seminary of Paris. THE IMPORTATION OF OPIUM.–The money value of opium imported through the Custom House of New York City, in the Year 1871, was $1,299,091. A TURKISH MEDICAL Journal.—The first number of a Medical Gazette in Turkish has made its appearance. The new periodical is printed at the Haïdar-Pasha Hos- pital—Practical School of Medicine. VIRCHow PERIPATETIC-According to a letter from Berlin, Virchow has journeyed to Barmen to deliver a lecture to the citizens union on “The Development of the European Nationalities.” In a few days thereafter he is advertised to address the scientific society at Elber- feld on “The Boundaries between Instinct and Reason.” Thence he betakes himself to the Rhine to institute Some investigations into the cultivation of fish. 226 [MAY 11, 1872. TIEEI IED CT, I. N. T. C. THE JUGULATED CoILEGES.—The foreign journals (London, Vienna) notice with pleasure the suppression of the pseudo medical colleges in Philadelphia. AN OPPORTUNITY. —M. Gustave Ambert chief of the expedition to the North Pole wishes to find a young doctor of solid and varied (physical and natural sciences) attainments who would like to join the polar expedition, Address M. Ambert, rue de Verneuil 38, Paris. MEDICAL SENATORS.—Four Italian Physicians have been chosen to be senators of the kingdom; viz., Pro- fessors Stanilaus, Cannizzaro, and Maggiorani, of Rome, and Porta, of Padua. PROFESSORIAL PREREQUISITES.—It may be of inter- est to learn how professorial positions are filled abroad. The chair of clinical surgery being vacant, the minis- ter of public instruction advertises for candidates in the Gazette des Hôpitaux, Mar. 23, '72, as follows:— 1. Certificate of Birth. 2. Diploma in Medicine. 3. A note specifying the titles which may have been received and including a statement of all services in medical instruction with an enumeration of all the papers and works of which the candidate is an author. Having filled these necessary prerequisites to inscrip- tion as candidates they are then subjected to impartial competitive examination. THE PROMOTION OF MEDIOCRITY.-London is having the same trouble it seems in chemistry that Cincinnati is so sorely afflicted with in some other departments. The Brit. Med. Journal (Apr. 20, '72) descants as fol- lows: “The fact is, we believe that cliqueism has become of late years so rampant in chemical circles in this country, that independent ability is rather discouraged than promoted, and obsequious mediocrity has been studiously pushed into all the prominent posts in the country. In that dearth of useful and creditable work, which Dr. Frankland deplored, we are partly reaping the result of this system.” —º-º-º- CORRESPONIDENCE. A Point in the Diagnosis of Uterine Polypus. DAYTON, OHIO, May 1, 1872. EDS. CLINIC: * In my remarks on uterine polypus published in your journal last week, I mention a certain condition of the lower portion of the tumor, an opening betwen its fibres, causing it to closely resemble the os uteri, as having been once found by Scanzoni, and quote his statement that he has but once met with it in his own experience and has been unable to find any similar case recorded in the earperience of others / Scanzoni is certainly | tincae and cervical canal. high authority and I may be pardoned for relying upon his testimony as to the very great variety of this condi- tion of things. Yet, within a few days, in casting my eye over the pages of ARAN's* works on Diseases of the Uterus, I met with the following paragraph which cer- tainly seems worth quoting in connexion with this subject: - “One circumstance worthy of attention in connection with diagnosis is that the base, or free extremity of the polypus, sometimes presents an infundibuliform de- pression, or even an excavation, into which the finger or sound can penetrate, and which resembled the OS Examples of this kind have been reported by Levret, Richerand, Velpeau and Clogvret; but the most curious cases are those presented by M. M. Marcé, Boscredon and Dolbeau to the ana- tomical society. In Marcé's case “the polypus was not only elongated and conical, like the neck of the uterus, but it also presented, in the middle of its extremity, which was slightly flattened, a transverse opening; this opening was the entrance to a cavity communicating with the interior of the cervical canal and by this open- ing the menstrual flow found exit.” Yours, etc. J. C. Reeve. —-º-º-º- C. LIN (CAI, MEMORANIDA. GUARANA A REMEDY FOR SICK-HEADACHE. By Samuel Wilks, M. D., F. R. C. P., Physician to Guy's Hospital.-I wish to draw the attention of the profession to guarana as a remedy for sick-headache, and at the same time to ask for the experience of those who may already have some acquaintance with the drug. My own knowledge of it dates about two years back, when, after the appearance of a lecture of mine upon sick-head- ache, I received a letter from Mr. Helmcken, of British Columbia, enclosing two powders which he recom- mended to me with much confidence as able to cure the complaint. He said that, having heard much of the remedy, “I resolved to try the medicine upon one of my patients who was always coming to me with sick- headache; and sure enongh it acted like a charm; and in place of suffering for twenty hours or so, the headache had disappeared in a couple. This accords with what others have told me.” Upon my first headache after the receipt of Mr. Helmcken’s letter, I took the powder but with only doubtful effect. I therefore did no more than casually mention the medicine to my friends, but did not recommend it. A few weeks ago, after the ap- pearance of a second communication of mine in the Journ AL upon the same complaint, I received a letter from Dr. Wood, of Montreal, in which he also recom- mended “guarana” as a remedy for headache, and gave *Traité pratique des Maladies de l’Uterus deuxième ed; avec la collaboration du docteur A. Linas. Paris, 1869. MAY 11, 1872.] T+H: H] c LINI c. 227 a history of his own personal sufferings and the relief which he had obtained. He says: “By taking one of these powders and remaining quiet when I have felt premonitory symptoms by a beginning of pain always in the right temple (headache on the other side, or in any other part of the head, I never mind), I have carried off the attack; and, with the first box, absolutely put it off for two months—something which had never occurred in my life before.” Upon so good an authority, I determined to try the remedy in a more systematic manner, and requested my neighbor, Mr. Hooper, the chemist, to procure me a packet of the powders. These I have recommended to several patients and friends; and the result is so encouraging, that I have hastened to suggest their trial to my professional brethren. One lady speaks most enthusiastically of their power, as she has now, on two seperate occasions, had her headache arrested by their use. The drug has long been known, for mention is made of it in English and French phar- macologies but appears never to have come into general use. It consists of the seeds of a tree growing in Brazil called Paullinia Sorbilis;and these, according to Johnstone in his Chemistry of Common Life, are used as we do cocoa. The seeds are ground into powder, and contain an alkaloid which is said to be identical with that found in tea and coffee. The medicine is manufactured by Grimault and Co., No. 7, Rue de la Feuillade, Paris.- Brit. Med. Journ. Apr. 20, '72. THE CONDITION OF THE LABYRINTH IN CEREBRO- SPINAL MENINGITIS.—The cases of disease of the Semi- circular canals described by Menière as well as those of deafness after cerebro-spinal meningitis by Moos (Klinik der Ohren-Krankheiten p. 325), Voltolini explains as resulting from inflammations of the labyrinth. As regards treatment the most different means produce no result. Heller examined the ears in two cases of purulent cerebro-spinal meningitis. In one, the cavity of the drum on both sides contained fluid pus as did also the ampulla and the strongly congested cochlea in its lamina spiralis membranacea. The auditory and facial nerves on both sides were imbedded in pus. In the other case an almost similar condition was observed. In both instances there was a purulent affection of the external and middle ear. The inflammation may have extended out from the meninges through the internal auditory canal and thence extended itself to the labyrinth for which the condition of the auditory nerve is evidence in proof or it may have developed in the tympanic cavity and labyrinth simultaneously with the meninges.—Schmidt's Jahrbücher, Bd. 148. 2, 1870, p. 252. CHLORAL IN THE TREATMENT OF WENEREAL UL- CERs.--Dr. F. Accettella has employed very strong solutions of chloral as topical applications to chronic ulcers that had resisted treatment by the acid nitrate of mercury, the carbo-sulphuric paste and other very active caustics. The result surpassed his expectations. After the first applications the bottoms of the ulcers cleaned off, healthy granulations sprung up and the ulcers were converted into simple sores. The author employed a Solution one part to four, (R. - Chloral Hydrat., gr. a-v. Aquae Destil., 37. M.). brushed lightly over the surface of the ulcer. For erosions and simple ulcerations he employs a more dilute solution.—Bull. Gen. de Ther., Mar. 30, 1872. THE TREATMENT OF CROUP.—Dr. Daguilon recom- mends (Gazette Hebdomadaire, 1871) the following treat- ment when symptoms of suffocation from croup are imminent: A sponge, after being dipped in pure liquor ammoniae, is to be squeezed until no more liquid drops from it, and is then to be passed, by means of a whale- bone probang, down the throat. The child should be compelled to inhale the vapor of ammonia as long as it possibly can. The immediate result of this treatment is an abundant Secretion from the respiratory mucous membrane and the expectoration of false membrane; the dyspnoea diminishes, the cough is less hollow, and the voice is less muffled. Often, in cases where death seemed imminent, the lives of children have been saved. —Phil. Times, Apr. 15, '72. OPACITIES TATTOOED.—In 1868, Mons. de Wecker introduced the operation of tattooing with India ink, with a grooved paracentitis needle, in those unsightly and disfiguring cases of opacities of the cornea, which very successfully and happily ameliorates and dispels those great deformities. He has operated upon forty cases, and every one has been greatly improved. Each case usually requires from six to eight tattooings, and they can be repeated at intervals of about eight days. The result is permanent. We have watched, with much interest, the case of a young lady who had been tattooed a number of times during the last six months, and who, for three months, has been under our observation. It is impossible to tell which is the tattooed eye at a distance of three feet, it so closely resembles the sound one. In fact, so successful has been the result, that it is necessary to raise the upper lid, and make a close in- spection, to perceive that the eye has been tattooed.— Paris Letter to Nashville Journ. Med, and Surg., April, '72. IMPOTENCY.—Prof. D. Hayes Agnew, of Philadelphia, Pa. (Med. and Surg. Reporter), in a clinical lecture on impotency, after stating that the treatment must be largely moral, and urging the abandonment of onanism or excessive yenery, says that there is no better internal treatment than phosphorus and strychnia—1–50 grain of the former, and 1–30 of the latter—made into a pill, and administered three times daily, THE SIGNIFICANCE OF Wom ITING IN HERNI.A.-If I were asked which of the signs of strangulation I would 228 [MAYH 11, 1872, THE CI.INI c. most rely on as commanding the operation, I should certainly say the vomiting. Time after time, when the other signs were feebly, if at all, marked, the vomiting has been a sufficient guide to a timely operation. times, when all else was so quiet it seemed rash to operate, the vomiting proved it would have been much more rash to wait; and not one instance can I find in my notes in which neglect of the import of vomiting was not proved to be unwise. You had better hold the rule complete, that, when a patient has a hernia, recently become irreducible, and, with this, vomiting which, cannot be clearly assigned to something independent of the hernia, you shall operate. I am obliged to Say recently become irreducible, because a patient with an old irreducible hernia may vomit, as any one else may without any reason for suspecting strangulation; though in even these old cases you must be very watchful lest the vomiting be an early sign of strangulation. But the rule is safe that recent irreducibility and vomiting are enough to justify the operation, even be there no other signs of strangulation present. Much more must the operation be deemed necessary when with these the other signs of strangulation, in even slight degrees, coincide. - And in this judging of the vomiting, do not be too scrupulous as to its manner or its products. There are indeed some notable modes of vomiting when the intestine is strangulated. The patient vomits all he drinks, and that soon after taking it; and besides, he vomits fluids of his own secreting; and this vomiting is commonly (at least in the later stages), with gushes of large quantities of fluid, without much retching or violence, as if the stomach slowly become full of its own Secretions and of those of the upper part of the intestine, aud then, without any preceding nausea, suddenly emptied itself. When you see these kinds of vomiting with a hernia lately become irreducible, or even with any swelling that may be a hernia, you may be sure that you must operate. But do not wait for any characteristic mode of vomiting; do not be misguided by the absence of some peculiar fluid ; nay, do not be misguided by the absence of all vomiting; for I have known it absent in the case of a very large hernia, which was certainly strangulated, and on which I operated successfully. And do not be misguided by an apparant diminution in the severity or in the frequency of vomiting, or by the vomiting having begun as soon as the hermia descended; for this it often does. Any kind of vomiting if it be repeated, is enough to justify operation in a hernia recently become irreducible.—Paget–Brit. Med. Journ., Apr. 13, '72. AUTOPLASTY ON THE HAND WITH SKIN FROM THE ABDOMEN.—Dr. Delore, surgeon at the Charité (Lyons), recommends the transplantation of skin from distant places in relief of vicious cicatrices, etc., as follows: There is a method of cheiroplasty which is susceptible of useful applications. It is the method of the Italians which consists in removing a surface far from the place Many to be applied. I have not found, he continues, traces even of its adoption in the various treatises on surgery, Tagliacozzi did use this means for the nose, whose restoration, however important, is not of the necessity of that of the hand. He dissected skin from the upper arm and permitted it to suppurate before applying the suture. The article concludes with the report of a case of transplantation from the abdomen for the relief of a vicious cicatrix of the little finger.—Lyon Médicale, April 14, '72. THE DIAGNOSIS OF HYSTERIA.—Dr. Chairon insists upon it still that his symptom of hysteria as described in his work (Etudes cliniques sur l'hysterie, Paris, 1870) is characteristic. This constant and pathognomomic sign is insensibility of the epiglottis to reflex action. And how is this constant reflex insensibility to be ascertained ? - In the beginning of the malady, he observes, in the absence of every other phenomenon, if the finger be carried to the base of the tongue it will be seen that the epiglottis, which is raised, is insensible. One may irri- tate it with a feather or any other light body, carry the finger even over the superior orifice of the larynx al- most to degree sufficient to jprevent the passage of air and produce a light degree of asphyxia and still there will be no effort at vomiting. - The author insists, further, on the extreme caution with which this operation is to be undertaken. He recommends the introduction of the finger over the tongue and gliding it down gently to its base. In this way it quickly comes in contact with the epiglottis which may be titillated, touched, even scraped with the nail without exciting the least effort at regurgita- tion. . - This single sign has often permitted a certain diag- nosis of hysterical affection in cases in which the disease manifested a few days thereafter in complete attack.-- Gaz, des Hôpitaux, Mar. 16, ’72. . —-º-º-º- THE RIGHT MAN.—Just on going to press we learn that Dr. J M. DaCosta has been elected to the chair of Practice in the Jefferson Medical College, vacated by the death of Prof. Dickson. IHOMIE NEWS. SMALL-Pox lingers as if loth to leave us. Deaths during the past month have averaged about ten per month. The disease is almost exclusively confined to the unprotected by vaccination or previous attack. CEREBRO-SPINAL MENINGITIS, our new and equally unwelcome guest has rather retreated than advanced since our last report. Mr. George Boone, now on his travels, is the only author- ized agent and canvasser for THE CLINIC for the South and West, - MAY 11, 1872.] TIEEI IEH C T , T INTT C. A M ER Ic AN ºr ED 1 o AL As so or A Tro N. 28th Annual congress. º : PHILADELPHIA, MAY 7, 1872. EDS. CLINIC, The “National American Medical Association” held its 25th annual meeting here to day. This is the third time that the “Quaker City” has been honored by its sittings; and it certainly deserves that honor, for here was the birth place of the association and here it was that the science of medicine in America received its first impetus. The glory of Philadelphia's medical history will never grow dim, associated, as it is, with reminiscences of the “University” and “Jefferson” and of the many great minds that from the days of Rush and Physic up to the present time, held, and still hold by the charms of their medical teachings countless aspir- ants for the title of “M.D.” spell bound. **, The convention was promptly called to order at 11 o'clock A. M. this morning. Its place of meeting is at “Horticultural Hall.” judging from present appearances will be none too large The hall is a large one, but for the accommodation of the numerous delegates who still continue to throng in from all parts of the country, every state and territory being represented from Maine to California. , 519 names had been enrolled up to 11 o'clock, and “the cry was still they come.” - After a short prayer by “Bishop Stephens,” President The ad- Possessing the charms of Yandell, of Louisville, delivered his address. dress was a magnificent one. a fine personal appearance, a loud and clear voice, and the language of action to a most graceful degree. Dr. Yandell held the delighted attention of the convention throughout. ' + . . . - The first part of his address was devoted to the past medical history of Philadelphia, and he paid a most de- serving tribute to the memory of the great men, who, though they have quitted this sphere of worldly nation, left behind them lasting monuments of genius. By far the greater portion of the address was on the subject of medical education. He was opposed to the present Utopian scheme of founding so-called “National Med- ical Universities.” He criticised the present system of medical teaching as practiced in Germany; conceding to the Germans the highest place in medicine, as regards their labor, researches, and literature in the fields of pathology, microscopical anatomy, and medical chem- istry; and paying a high compliment to their obstetrical . contributions to the science. He was opposed to their | “practice,” it seemed to him that their therapeutics |were a mere “reflection on death.” He touched lightly on the subject of the admission of women to the association, was rather opposed to female physicians, still, if a woman would study medicine, so be it. He spoke of the harmony that had heretofore existed in the organization, and hoped it would always continue to exist. He was very careful not to allude to the dis- turbance created at Washington sometime since by the attempt of colored delegates to gain admission to the convention. The address is said to be the best ever de- livered before the association ; at its conclusion came the bomb-shell which threw the convention into an uproar. It was darkly hinted several days before the convention that an attempt would be made by the friends of the colored delegates to force them into the association. Dr. Yandell had hardly concluded, before a communication in the form of a resolution was pre- sented by a Dr. Askell of Del. This brought Dr. Mussey of Cincinnati to his feet; to cut matters short, it was a repetition of the scene that is said to have occurred at Dr. M. offered a substi- tute to the resolution which was rejected, and the whole Washington sometime since. matter was referred to the committee on ethics; what its fate will be remains to be seen. Should a majority of the association vote in favor of admitting colored men to membership, I predict a disturbance, and a probable bolt of the southern delegation from the convention. Drs. Carson, Mendenhall, Gobrecht, Comegys, Koen- ner, Norton, Heighway, Henry Richmond, Rasching, Walker and other Cincinnati delegates arrived this morning. - The programme So far arranged for the amusement of | the delegates is extensive. Promenade concerts, recep- tions, excursions, exibitions, and visits to Hospitals, etc. Weather fine and all seeming to enjoy themselves. M P. S. No Banquet. [This letter came to hand after our forms were locked for press, consequently too late for insertion in its proper place. However excellent and able the address of the Presi- dent in other respects it is a matter of regret that the occasion was used to strike that old and worn out cord, the popular twaddle about German “practice.” The readers of The Clinic have had abundant opportunity of deciding this matter for themselves, and no jingle of American rhetoric will be likely to mislead them]. gº Carriage Manufacturer, NOS. 9 and 11 East Sixth sº bet. Main & Sycamore. • . . I MAKE NOTHING BUT Jº Z/FS 7" C.A. & S.S. Wºº Jº M'. Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of - - LIGHT FAMILY CARRIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive variety of light elegant designs of different cost and finish. In vehicles especially adapted to - * PHYSICEANs' USE. The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. - The superiority of my light gentlemen’s buggies, road and trotting wagons, and racing work of every description, has long -Ea. been acknowleged. Catalogues and price TSN/X lists furnished on application. References K - to Dr. W. W. Dawson and all the leading J wº tºss Physicians in the city and heighborhood. . -e-E- - * = E" A C Uſ I, T Y. J AM ES G R A H A M, M. D., DE AN, Professor of the The ory and Practice Of Medicine and Clinical Medicine. ROBERTS BARTHOLOW, M.D., W. W. DAWSON, M.D., Professor of Materia Medica and Therapeutics. Professor of Principles and Practice of Surgery and Clinical Surgery W. H. GOBRECHT, M.D., C. D. PALMER, M.D., Professor of Anatomſ). Professor of Medical and Surgical Diseases of Women. P. S. CONNER, M. D., T. A. REAMY, M. D., Professor of Surgical Anatomy. Professor of Obstetrics and Diseases of Children. JAMES T. WHITTAKER, M.D., - JOHN L. CLEVELAND, M. D., J’rofessor of I’hysiology. Demonstrator of Anatomy. SAMUEL NICKLES, M. D., CHARLES KEARNS, M. D., Professor of Physics and Medical Chemistry Assistant to the Chair of Surgery WV . VV - SICEL'Y', MI. D., E*rofesson, o ſº I) i. easses of" ( H. G. Tºye an Čt HJar, and di Secre (a tºy of the Faculty ** *- T. Lot' is I3 ſtow N. M. ()., ſºrosecutor of Aſ naſotny, E. No BLE, Janitor, College JSuilding, Sixth St., bet. Vine and Race ~s --------- - - Printed and I'm blished jºy Noſ. It is & M tº Hity, Medical College of Ohio Building, Cincinnati. THE XLINI C. PUBLISHED EYERY SATURDAY. TERMS-$2.00 a Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editors 3- S vol. 2. ' *: CIN cIN N ATI, All Communications relating to Business, Subscriptions, Advertis ements, etc., to the Treasurer. ~&- —º —º 20. —º-2 —ºxº~. M A Y 18, 1872. No. JAS. T. VVHITTAKER, M. D. No. 101 West Ninth Street, Cincinnati. ...A-SSOCI.A.T.E. Hi-DITOR.S. W. W. D.Awson, M. D. Thad. A. REAMY, M. D. P. S. Conn ER, M. D. C. D. PALMER, M. D. . W. W. SEELY, M. D. SAMUEL NICKLEs, M. D. CHAs. KEARNs, M. D. - . . . . . RoHERTs BARTHollow, M. D W. W. SEELY, M. D., * No. 118 West Seventh Street, Cincinnati. C L U B R A T E S, . Editor, • : g- JNo. L. CLEvKIAND, M. D. : TREAsukeR, . f # & 4 Copies to one address............….................................... $ 7.00 6 {{ “ .............................................a....... 10.00. I2 44. {{ : * 18.00 C O N T E N T S. sºmºmºmºsº Page. A NIE R 1 C A N M E D 1 C A L. A SS-O C.1. A T 1 0. Nº Twenty-third Annual Congress. The Transactions in Full TUESDAY-Morning Preliminaries—Exércises Commence—After- noon Reports—Evening Entertainments * * * * * * * * * * * * * * * g is e º a tº e º e º 'º e s e º º te e º is º Wednesday—A Change of Base—Publication and Funds—The —º-º-º: coaxN se ce. hionable Hatters, IMPORTERS AND MANUFACTURERS OF *Anºsº Furts, Fas # , - * * 92 wrest FOURTH st'. opposite Post office, CINCININATI. §sirspecial Inducements to Medical Men. < * f * - .# RogaRºgrillman |ENGRAVERSºwooD º Prize Essay—Medical Literature—Essays and Reports—The Contract System—Evêning Entertainments—The Receptions....230 TirursDAY--Animal Disease—-Poison Labels—Alcohol—-Officers Elect—The Health of the Sphere—A Warning—The Various Committees—Officers of Sections—Ethics, Exit Bliss—The Ine- vitable Contest * * s • * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * 232 FRIDAx–Resolutions of Regret—Medical Experts—Votes of Thanks —A Last Effort—Adjournment--Thé Pavillion Collation—The Departure ---...--.......... * * * * : * tº s ſº e º ........,235 - - ORIGINALL ARTEq} . ES * Sub-Involution of the Uterus by Prof. Thad. A. Reamy........~. 236 Dysmenorrhoea by C. D. Palmer, M. D............................................ 238 ACADEMY OF MEDRCINE Transactions May 13, ”72. Paracentesis Thoracis, Paper by Dr. Bartholow—Remarks by Dr. Graham—-Purpura Hemorrhagica, Specimens by Dr. Miller, Cases by Drs. Muscroft, Reamy, Cleveland, Judkins, Ludlow--- Specimen by Dr. Maley---Procidentia. Vesicae, Case by Dr. Ludlow---Morphia Hypodermically in Cholers, Paper by Dr. * * tº w 24() * * * * * * * * * * * * * * * * * * * * * * * g º $ tº gº tº wº We are indebted to Drs. F. B. Morris of Hamilton, T. C. Minor and M. L. Nardyz of this city for com- plete and early reports, letters and papers from which the full transactions of the association have been com-g piled. While acknowledging this debt of gratitude, however, we take this occasion, to state that we publish the transactions of the association only because it is expected of us by the profession. Had we been able to secure short abstracts of the papers read,&esults of experiments performed, etc., we could have º our columns with better grace. ¥ Meanwhile, however, valuable information is accu- mulating both in original matter, and selections and, the present digression over, THE CLINIC will be Continued as heretofore. ºf SºfºgFiºsº CINCINNATECHIO: § *- *** **** J. TAFT, W. TAFT. J. & W. TAFT, TIENTTIST's 117 WEST FOURTH STREET, CINCIN NATI, O. A Monthly Journal, CONTAINING 48 PAGES, Devoted to the Interest. ':e Dental Profession, MARVIN's coL LIVER, OIL o B C R. L.E. s.s A.N D PALATA H. L.E. In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERs & BARTIETT, of Portsmouth, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. R Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. - Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachilic Affections, in Chronic Rheumatism, &c. - - The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. ---------- JAMES FOSTER [ESTABLISHED, 1836.] Importers and Manufacturers of Optical and Physical Instruments, Keep constantly on hand first-class English and French Microscopes, and Microscopical Apparatus of every descrip- tion, Medical Baiteries, Thermometers, Hydrometers, Urinometers and * Chemical Glass Ware. Fºl attention given to adapting the best spectacles to all conditions OI Signt. - • , - We take pleasure in showing the latest novelties from the best Euro- pean and American manufacturers. - - - JAMES FOSTER, Jr. & Co., S. W. cor. 5th & Race Sts., Cincinnati, O. First-class Objects| TER.S.N.M AIR's Hºs F. E. SUIRE. E. S. WAYNE IF. T.C. Suire & Co., | WHOLESALE DRUGGISTS, IN/[ _AL INT TJ ET A C T TJ IER, IT INT G- £Hemists AND PHARM aceutists, CINCINNATI, OHIO. Have constantly on hand a full assortment of sex. Ecºexºd ox{UGS ANYO IVX)expxcxxxes, cºeryxxcAX, APPARAºcus, TESTS, MEDICAL, GLASS WARE, &c, &c., And solicits the patronage of the trade and profession. We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, Made in accordance with the U. S. P. and other recognized authori- ties. FINR, ANT) ERAEHL CHEMICALs, Of the popular class of preparations known as IE T IDX IIR, S, We manufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. - Bitter Wine of Iron, An excellent Chalybeate and tonic, Wine of Isen, &c. AGENTS FOR BULLOCK & CRENSHAW's Sugar-coated Pills and Granules. Price Lists of preparations and of Sugar-coated Pills sent by Mall upon application. The long standing and well and widely known repu- * - - No. 758 BROADwAY, NEw York I HAVE been in the habit of applying and recommending the Truss manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined. LEWIS A. SAYRE, M. D. Surgeon, Bellevue Hospital. * From Prof. Willard Parker to S. D. Townsend, M.D., Surgeon to the Massachusetts General Hospital, BEG leave to state for the benefit of all concerned, that I have known l)r. S. N. Marsh the last fifteen years. * * I am in the constant habit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with any of the risks to the patient that ēxist in many of the plans suggested and attempted to be carried into execution. I have confidence in Dr. Marsh as a gentleman of honor and integrity, and as such recommend him to the members of the medi- cal profession generally. ILLARD PARKER, M. D. - Professor of Surgery, New York City- Dr. S. N. Marsh's Patent Radical Cure Truss and all other kinds of Trusses, Shoulder Braces, Supporters, Elastic stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other. Physical Deformities; made and accurately fitted at the Radical Cure Truss Offices of S. N. MARSH & Co., No. 2 Wesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. oppositE THE HIGH STEEPLE, R&’ Agents for Clement’s Patent Artificial Legs. tation of our house we offer as a guarantee for the reliability of our preparation, and the quality of the goods sold by us generally. List ºf Pharmaceutical Preparations, MANUFACTURED BY Jonºv ryaznº anorman, FEHirº AIDELIFECIA- ,” —-º- ELIX. PHOS, IRON, QUININE AND STRYCHNIA, - ELIXIR OF GENTIAN FERRATED, ELIXIR WALERIANATE OF AMMONIA, - - (Goddard’s Formula,) - - EitzińvaLERIANATEAMMORIA AND QUININE, ELIXIR OF THE FYROPHOSFHATE OF IRON, Iron, with Phosphorous amd Calisaya, FERATEDELIXIE OF CINCHONA, ELIXIR OF CALISAYA BARK, - , ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, - COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER WINE OF IRON, Citrate of Iron and Peruvian Bark, - FERRATED CORDIAL ELIXIR, ELIXIR CALISAYA BARK, WINE AND BISMUTH, * * ELIXIE CALISAYABARE, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, - - * TASTELESS COD LIVER OIL, TASTELESS CODLIVER OIL. FERRATED, - - BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and sherry wine, ELIXIR WALERIANATE OF STRYCHNIA, wing OF PEPSIN SYRUPSUPERPHOSPHATE OF IRON, ---------, - ELIXIR OF BISMUTH, COMP. FLUIDEXT, BUCHU AND PAREIRA BRAVA. STUTEPIEPOSITOTERITES. Rectum, Vaginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great eare, and of every variety of combination. Lists sent on application. SPONGE TIENTS.—For the Urethra, of every size and Btyle, made of finest quality of sponge. Carriage Manufacturer, Nos. 9 and 11 East Sixth Street, bet. Main & Sycamore. ! I MAKE NOTHING BUT rzwsz, czzz'ss ºro wr, Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of LIGHT FAMILY CAFFIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive variety of light elegant designs of different cost and finish. In vehicles especially adapted to § , PHYSECHANS” (SE, The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. The superiority of my light gentlemen’s buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price : º º Ni e-Sº Z_\ \ ^ lists furnished on application. References to Dr. W. W. Dawson and all the leading Physicians in the city and heighborhood. 83 DIVIDED MEDICINES, PREPAIRED BY The Divided Medicine Com’y, CINCINNATI, OHIO. The Company have the honor of bringing to the notice of the Profession, this NEW AND ExcEEDINGLY PRACTICAL METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. The Divided Medicines are prepared by FREDERICK KRAUs, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MORE. $º. The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every Square will consequently contain accurately measured quantities. But not only SOLUBLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINES. * 2. This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, ; , , , ºo, and even idoo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE TO SPOIL BY ANY LENGTH of TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calls with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. For samples, Price Lists, and Agencies, address The Divided Me § Nº N3 JEO 2688, Or FRFDERICK KRAUS, Chemist and Druggist, Walnut Hills, Cincinnati, O. MR. FREDERrck KRAUs: CINCINNATI, February 15, 1871. Dear Sir—The specimens of your “ Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: SULPH:MORPHII....................... % grain in each square. ARSEN:ACID.......................... 1-20 grain in each square. ** CH IN INI .......................1 ** * * 66 CALOMEL 34 “ -- {{ “. COPPER ........................ % 6& ResPECTFULLY YoUBs, E. S. WAYNE, Analytic Chemist. T TH. H. C. T., T N T C . 229 Vol. 2.] S A T U R D A Y, M A. Y. 18, 1872, A M E R II Cº. A N M E 10 I (; A L A S S O C I AT I O N . TWENTY-THIRD ANNUAL CONGRESS. The Transactions in Full. :: PHILADELPHIA, PA., MAY 7–10, 1872. Special Correspondence of TITF CLINIC. TULESHPAY. Morning Preliminaries. At eleven o’clock this morning there was opened the first session of the meetings of the American Medical Association. A very large number of gentlemen are in attendance, as well as many of the softer sex, all come to take part in or listen to the proceedings of the Asso- ciation, as these should gradually unfold themselves. The number present exceeds that of any previous con- vention ever held. During the morning the delegates assembled in Horticultural Hall, and there for a consid- erable time occupied themselves in the courteous inter- change of friendly greetings with brother professionals, with whom they had not associated for many years. The association is composed of delegates from local so- cieties over the whole United States and from colleges, hospitals, lunatic asylums, and other permanently organized medical institutions of good standing in the United States, from the army and navy and from the American Medical Society of Paris. Prof. Wm. H. Gobrecht is registered as the delegate from the Medical College of Ohio, Drs. Comegys and Carson from the hospital and Drs. Walker, Nardyz and others from the Academy of Medicine. The large number of delegates present, occupy about two-thirds of the floor of the hall which had been railed off for their use. The remainder of the floor and gallery was at the disposal of spectators, among whom were a large number of ladies. Every arrangement was made for the convenience of the body in transacting its business. The attendance is nearly one thousand in number, of men of more than ordinary talent and appear- ance of intelligence. The Evercises Commence. Shortly after eleven o’clock the association was called to order by the president, Dr. T. W. Yandell, of Louis- ville, Kentucky. [No. 20. The proceedings were opened with an appropriate and impressive prayer by the Right Rev. Wm. Bacon Stevens, M. D., D. D., D. C. L., Protestant Episcopal Bishop of Pennsylvania. The address of welcome on behalf of the medical pro- fession of Philadelphia was delivered by Professor R. E. Rogers, M. D., chairman of the Committee of Recep- tion. The greeting in behalf of the Committee of Arrange- ments was delivered by TEdward Hartshorne, M. D., of that committee, who then recited the programme of entertainments arranged for the strangers during their stay in the city. Dr. William B. Atkinson, of Philadelphia, permanent secretary, read a list of the delegates whose credentials have been approved. President Yandell read the annual address, which was a very long and erudite paper, pleasantly relieved with dashes of anecdote and humor. [An abstract of this address has already been pre- sented to the readers of THE CLINIC by a former cor- respondent]. A vote of thanks was passed for the address of the President. The report of the Committee on Credentials was pre- sented as far as read. Drs. Morris J. Ash, U. S. A., M. W. Junker, of Bellaire, O., and David D. Mahan, of Mifflin county, Pa., were elected members by invitation. Dr. H. F. Askew, of Delaware, offered a resolution that all questions of a personal character, including com- plaints and protests, and all questions on credentials, be referred at once to the Committee on Ethics, and with- out discussion. Dr. Mussey, of Ohio, asked that the motion be di- vided, referring questions of personal character only to ..he Committee on Ethics. * Br. Askew declinol to accept the amendment for a division of the question. Dr. Mussey asked if the question did not concern the rights of societies to be admitted in convention, and if so he denied the right of the committee to decide upon such questions. He proposed, also, reflrring th second branch of the subject to the convention. The Chair said that such a course had never been pursued. Hitherto the Counºnittee on Ethics reported to the convention on both subjects, their action being open to the approval of the convention. Dr. Hartshorne said that the course of the Committee of Arrangements was plain and defined by law, and the original resolution was framed in accordance there- with. The previous question being ordered by the house, Dr. Askew's motion was put and carried without a dis- senting voice. Various reports were next announced on the subject of papers to be read at the sections held in the after- IłOOIl. 230 [MAY 18, 1872. T EITH C T , T: TNT I C. The following gentlemen were appointed the Com- mittee on Ethics: Dr. Askew, of Delaware; N. J.Davis, of Illinois; Calvin Slavy, of Maine; I. K. Bastette, of Delaware; and S. D. Gross, of Philadelphia. The session then ad- journed. In the afternoon, the various sections of Practice and Obstetrics, Surgery, Anatomy and other medical and scientific branches met in different portions of the hall as designated on the delegates tickets, for the purpose of hearing reports of Special Committees on Climatology, Epidemics, Surgical Operations, Ophthalmology, &c. Evening Entertainments. In the evening, a reception was given at Horticul- tural Hall, by the Biological Society. In the foyer were arranged two long tables, on which were placed over one hundred powerful microscopes, containing specimens of pathology, anatomy, microscopic photography, etc. |Upon the platform at the end of the room were arranged five spectroscopes, in charge of Professor B. H. Rand, of the Jefferson Medical College, who exhibited the spectra of the different mineral and other substances, and of the electrical light. During the evening a promenade concert was given in the main hall by Hassler's Orchestra. The visitors were greatly interested in the display and pleased with the entertainment. Among the specimens examined under the microscope were fleas, beetles, fang of a rattle- Snake; human, insect, and animal blood; Egyptian mummy hair, the human nerve trunk, sections of the eye, lungs, heart, kidneys, cancer of the mammary glands; photographs of Nobert's test plates, ninth and nineteenth bands, from the Surgeon General’s office at Washington, etc. The following is the committee of arrangements ap- pointed by the Association: E. Hartshorne, M. D., Chairman; Richard H. Town- send, M. D., John H. Rackard, M. D., William Pepper, M. D., F. F. Maury, M. D., James Tyson, M.D., S. W. Gross, M. D., D. Murray Cheston, M.D., Secretary. & WELONESPDAY. The delegates to the American Medical Association assembled in Horticultural Hall at 10 o’clock this morning. The attendance was even larger than on the day previous. Shortly after 10 o’clock the association was called to order by Dr Thomas M. Logan, of California, first vice president, who stated that a recess of fifteen minutes would be taken for the purpose of organizing State delegations and electing members of a general committee of one from each delegation to nominate officers for the en- 8uing year, and name the city for the next annual meeting. A Change of Hall. At the close of the recess the association proceeded to Dr. Wylie's church, Broad street, below Spruce, where the session was resumed. This move was rendered necessary owing to the difficulty of hearing in Horti- cultural Hall. Nearly seven hundred delegates took seats in the church at 11 o’clock, and the work of the convention proceeded with much less confusion than was reasonably anticipated as the result of the sudden change of base. At the church, Dr. Yandell, president, of Louisville, took the chair, and the secretary read the list of members selected as the Nominating Committee, when they re- tired for consultation. Dr. W. H. Pancoast announced through the commit- tee of arrangements, that the ladies were also invited to be present at his reception in the evening. It was subsequently announced that Dr. Hugh L. Hodge had also made arrangements to provide for the ladies accompaning the delegates to his reception. Dr. R. E. Rogers offered a resolution inviting Dr. J. Edgar Chancellor, of the University of Virginia, to a seat on the floor of the house, which was adopted. Dr. R. Bronson, of Massachusetts, offered a resolution providing that the committee on Ethics, to consist of seven members, shall be chosen hereafter by the com- mittee, on Nominations instead of by the président, as heretofore. The President thought this was virtually an amend- ment to the by-laws, and should lay over under the rules. Dr. Bronson replied that the resolution might be passed at this session to take effect at the next session of the association. This idea was entertained by the Chair, and after an explanation by Dr. Bronson, that his resolution was offered for the sole purpose of Securing harmony, a vote was taken, resulting in the defeat of the resolution by a vote of 163 yeas and 187 nays. Mr. Van Bibber, of Baltimore, moved that a special committee be appointed to investigate the merits of a certain nameless substitute for quinine. The Chair stated that under the rules the matter must be referred to the section on materia medica. Dr. Davis, of Chicago, read a preamble and resolution endorsing the efforts of the Massachusetts State Society in crowding out quacks, charlatans, and pretenders from the profession, which subject was referred to the Committee on Ethics. The secretary asked that Dr. Edward Seguin, of New York, be permitted to exhibit his method of examining patients with a thermometer. Dr. Davis opposed this violation of the rules as estab: lishing a troublesome precedent. The president remarked that he was accused the day before of being discourteous, and he was now disposed to exercise all the courtesy he could. Dr. Seguin was told to present his method to the proper section. The regular business of the association was then resumed. MAY 18, 1872.] TIEEI IEH C T II INTI C. 231 Reports on Publication and Funds. Dr. Francis Gurney Smith, of this city, chairman of the committee on publication, presented his report. It set forth that 750 copies of the transactions of the society had been published, at a cost of $1,549.39. Of these 475 volumes were distributed to members, including 23 to various medical journals, and 88 copies are still due to members. The work was completed and issued early in November. The report concluded by reminding the members of a resolution passed in 1870 that all members who failed to comply with the rules of the association within one year forfeited their right to a copy. º Dr. Caspar Wistar, of Philadelphia, treasurer of the association, reported that the association last year exer- cised a praiseworthy discrimination in the selection of the material furnished for publication, and consequently the volume of transactions was smaller, more compact, cheaper and more desirable to the profession than here- tofore. The edition was published at a price which leaves a balance on hand for the use of the association when it may hereafter become forgetful of its prudênce, and refer a great mass of manuscript for publication. The treasurer counselled care in the adoption of prize essays, for out of this has arisen a considerable expense. The treasury is depleted annually to the extent of $200 which it can ill afford. The account current shows a balance in hand of $1,005, being about $300 more than was in hand last year. The expenditures during the year were $3,680. The treasurer asks the association to bear in mind that there are no discretionary powers vested in the committee on publication. They must publish everything which is referred to them by the sections. Referred to the publication committee. Dr. J. S. Weatherly, of Alabama, chairman of the committee on medical education, read the report of that committee. It urges the immediate suppression of the cheap medical colleges, through a petition to the State Legislatures asking for the withdrawal of all charters of institutions of a doubtful character. The committee recommended the adoption of a badge or medal, to be given to all physicians in the country who are deemed eligible for membership in the American Medical As- sociation. It is also recommended that the association shall establish a high standard for medical education and members, to be arranged by a congress of professors and practicing physicians and surgeons, all of whom are members of the American Medical Association. The Prize Essay. Dr. Francis G. Smith, of Philadelphia—In the absence of the chairman of the committee on prize essays, who is detained at home by a sad bereavement in his family —the death of his son Louis—and who has commissioned me, as the second member of his committee, to act in his place, I will present the report to the association. Four essays were submitted to the committee; of these, one was withdrawn by its author, and the remaining three were carefully examined by the committee. Two of them did not fulfill the conditions which are to de- termine the disposition of the prize. The third one did —that is, it presented the condition of original research, The title of that essay is, “What Physiological Value has Phosphorus as an Organismal Element,” and it bears a Latin motto—“Ne tentis, aut perfice.” The name of the author is Samuel R. Percy, of New York city. Medical Literature. Dr. T. Parvin, of Indiana, chairman of the committee on medical literature, reported that he had addressed a letter to each of his four associates—Drs. J. P. Whitney, of California; G. Mendenhall, of Ohio; H. Carpenter, of Oregon, and L., P. C. Garvin, of Rhode Island. He received replies from the two last named only. Dr. Carpenter said he had nothing to communicate. Dr. Garvin sent a long letter, which was read, and which contained observations in reference to the national literature and suggestions for its improvement. The writer asserted that we have an American medical lit- egature of which every one should be proud. This very city has produced works which would make quite a library of themselves, and without which no medical library, however vast and various its volumes, would be complete. The names of four of the living authors of Philadelphia who specially deserved mention are Geo. B. Wood, Hugh L. Hodge, Isaac Hayes, and Samuel D. Gross. Our literature, he says, is practical in character. Although we may boast of the grace and beauty with which Dr. Chapman clothed his thoughts; of the flash- ing declarations of the late Dr. Meigs; of the calm dig- nity and ornate periods of Dr. Wood, yet generally, our American authors give less heed to language than to ideas. If an author wishes to catch the ear of an Amer- ican physician, he must have something useful to say, and must say it quickly. The committee favored the idea of offering a triennial prize of $600 for the best essay, instead of the present plan of giving $200 to be divided between two each year. They suggest that the chairman of each Section deliver an address to his sec- tion, as likely to relieve Some of the irksomeness of listening to dry essays. A large portion of this report was devoted to advocating the publication of a national monthly journal, under the auspices of the American Medical Association. Referred to the publication com- mittee. Dr. J. D. Jackson, of Kentucky, chairman of the committee on American necrology, Submitted his report, which was referred to the committee on publication without being read. Essays and Reports. The secretary announced that Dr. J. G. Richardson, of Philadelphia, would read, before one of the sections, a paper on the structure of the white blood corpuscles. Also, that Dr. Hartshorne would read one on the physiology of the vaso motor nerves. 232 [MAY 18, 1872. TIH. H. C.L.INI c. Also, that Dr. Pancoast would present to one of the sections, through Dr. S. Bonaparte Merkel, the case of George Thomas. This is a colored man, a native of England, now a resident of Frederick city, Md., thirty- six years old, who makes a living by exhibiting his ability to roll his abdomen with an undulatory motion, like a huge ball, around the umbilicus, and also to move his heart from side to side. Also, that Dr. J. S. Packard, of Philadelphia, would exhibit to the surgical section a suspension apparatus for fracture of the leg. Also, that Dr. Hunt had sent in his report on the climatology of New Jersey. Referred. Also, that Dr. George M. Beard would read a paper on the recent researches in electro-therapeutics, with a demonstration of some of the methods of application. Also, that Dr. John P. Garrish would read a paper on “The use of instruments in obstetrics.” Also, that Dr. W. H. Mussey would read a volunteer paper on “A case of vesical calculus.” Also, that Dr. Harrison Allen would read a paper on “The soft palate in health and disease. * Also, that Dr. William F. Peck, of Iowa, would read his report of an operation on the hip joint, with details of the case. The Contract System. Dr. William R. Findley, of Pennsylvania, presented a resolution which declared that as the association, at its meeting in 1869, unanimously adopted a resolution classing all who practiced medicine on the “contract system” with “irregular practitioners,” and as this ac- tion has excited considerable controversy in many of the county Societies, the members of which have mis- understood the meaning of that resolution, it is therefore important that the committee on ethics decide whether such physicians are really “irregular.” Referred to the committee on ethics. Dr. George Sutton, of Indiana, read a report on “Com- parative Pathology,” in which it is urged that a national medical library should be established. Dr. Woodward, of the United States Army, observed that such a library is now in existence in the Surgeon General's office at Washington, and contains eighteen thousand volumes. - Dr. Pollock, of Pennsylvania, offered a resolution creating a special committee to consider the propriety of adopting the suggestions made in the report of the Committee on Medical Education, which was postponed for the present. t A long discussion ensued upon the matter of allow- ing the Committee on Publications to publish papers in the annual report at their discretion. The subject was finally postponed indefinitely. Adjourned. - In the afternoon the various sections and Committee on Ethics held meetings, at which a vast number of subjects were discussed, and among them the question of admitting the representative of the Howard Univer- sity (colored) and several colored physicians from Washington. Evening Entertainments. In the evening a lecture was delivered at the Univer- sity of Pennsylvania by Dr. Noyes, of New York, on “The relation of diseases of the inner structure of the eye to other affections of the body.” There was a large audience present, composed of the delegates, their fami- lies and friends. The lecturer showed the analogy between the diseases of the eye and those of other por- tions of the body, illustrating his remarks by means of ophthalmoscopic pictures projected upon screens by means of the magic lantern. At the close of this address the audience passed into the chemical lecture room, where Prof. R. E. Rogers delivered a short lecture on the two subjects of Spec- troscopy and Electricity. He first explained the action of the spectroscope in analyzing the light of the sun and other heavenly bodies, and also that produced by the combustion of minerals and gases, and in illustration he projected upon a screen the spectra of several of the substances alluded to. - - During the evening receptions were given to the delegates and their ladies at the residences of Dr. Wm. Pancoast and Dr. H. L. Hodge. TH [UIRSHDAY. The association re-assembled this morning at the ap- pointed hour in Dr. Wylie's church; President Yandell in the chair. A large number of physicians were on motion, invited to seats on the floor of the convention * After some preliminary business, Dr. Stein, of New ‘York, offered a resolution that a committee be appointed to examine and report upon the transmission of diseases from animals to man, and to report what measures may best be adopted to prevent and arrest disease in animals. Agreed to. - - A preamble and resolutions adopted by the College of Physicians of this city, the preamble reciting the frequency of cases of accidental poisoning by druggists and the resolution recommending that all bottles con- taing poison should not only be labeled poison, but should be roughed on one side So as to indicate their poisoning contents to the Sence of touch, and also be labeled with the most ready and efficient antidote, was upon motion, adopted by the convention. - A resolution offered by Dr. Horner, of Virginia, that the members of the association should discourage the use of alcoholic stimulants in their remedies, was adopted. There was one “No,” the enunciation of which produced considerable merriment. Dr. Walker of Brooklyn, presented a resolution that so much of the report of the Committee on Literature as relates to the establishment of a national medical journal be referred to a committee, to report at the present session. Agreed to. MAY 18, 1872.] committee on nominations. + TIH. H. C.T.I. NI c. 233 Dr. Francis Gurney Smith, of Philadelphia, chairman of the Committee on Medical Nomenclature, made a report with a resolution attached creating a special committee to prepare the classification and lists of names of diseases for publication and adoption by the asSociation. - Dr. Woodward, of the United States army, read a minority report, with a resolution appended, “that the classification and nomenclature proposed by the majority of the committee be printed in pamphlet form, and spread broadcast throughout the profession, and that the report be postponed for one year.” After a protracted discussion, Dr. Woodward's resolti- tion was adopted. - Dr. Keller, of Kentucky, then presented the following: Resolved, That so much of the report of the committee on education as refers to the establishment of a medical congress, consisting of an equal number of represen- tatives from each state, is of immediate importance, and, in order to further the views thus expressed, that a committee be appointed at once to take the preliminary steps necessary to organization with instructions to report before the adjournment of this convention. Before acting upon this Dr. William O. Baldwin, of Alabama, asked leave to make a partial report from the This was granted, and he announced that the committee had agreed upon the following officers to serve during the ensuing year: OFFICERS ELECT. President—Dr. Thomas L. Logan, Cal. First Vice-President—Dr. Catlin, Conn. Second Vice-President—Dr. McPheeters, Mo. Third Vice-President—Dr. Pollock, Pa. Fourth Vice-President—Dr. Briggs, Tenn. Treasurer—Dr. Caspar Wistar, Pa. Librarian—Dr. William Lee, D. C. Assistant Secretary—Dr. M. A. Fallon, Mo. Next place of meeting—St. Louis. The report was accepted. Dr. Baldwin requested further time for his committee to complete their report. - Dr. Keller's resolution was then voted upon and not agreed to. - * Dr. Palmer, in behalf of the delegation from Missouri, thanked the association for selecting St. Louis for the next place of meeting. Dr. Palmer then presented a proposition for the estab- lishment of a national medical academy, for the purpose of elevating the standard of medical attainments and the moral worth of its members. The association refused to adopt this scheme. The Health of the Mundane Sphere. Dr. T. M. Logan, of California, chairman of the com- mittee on “a national health council,” made a long re- port. The conclusions of this committee can be gath- ered from the following extract from the report: Diffuse the discovery of the means of protection against these and many other diseases which have been perfected under the vigilant outlook and investigation of combined chemical and microscopic detectives; ex- tend what has been successfully applied in circumscribed communities to states and to nations; let facilities for concerted action be established internationally through the instrumentality of governments, and the people will no more be decimated by those pandemic waves which have so often swept with cumulative impetuosity over the face of the earth. Utopian as the idea may at first sight appear of stamping out the great anti-Sanitary evils which beget disease, still it would be taking a very limited view of the power of the human mind, and argue a strange obliquity of vision as to the lessons its triumphs in other fields are every day teaching us, to doubt our ultimate ability to do so. “That man, who is rapidly subduing all the most Titanic forces of the universe to his commonest uses, should always remain at the mercy of these ignoble things is an antithesis too extreme to be permanent.” The government of the United States has already done something in the direc- tion toward which these suggestions tend, by the estab- lishment of a bureau connected with the war depart- ment, which makes constant synopses of the weather, storm currents and other meteorological phenomena occurring in some of the most prominent parts of the Union. Let the operations of the “signal service” be so extended as to reach the remotest expansions of the republic; and while there shall be sent from the capital of every state and territory full telegrams of the daily travail of nature in all her parts to the federal head, let the respondent wire report back simultaneously every- thing of scientific interest to the physician as well as to physicist. - The committee asked to be continued and to be con- stituted a special section on state medicine and public hygiene, to which all subjects cognate thereto may be referred; also that they be empowered to take such ac- tion, in connection with the authorities at Washington, as in their judgment may be deemed expedient in carry- ing out the objects of the resolutions. Dr. J. C. Tucker, of California, offered a resolution appealing to congress to establish a national sanitary bureau, in charge of competent medical men, to be ap- pointed by the United States treasurer, from physicians nominated by this association. The bureau was to have charge of all govermental hospitals, and was to secure the proper supply of bovine virus, besides performing many other national duties. The plan of Dr. Tucker was very elaborate and con- tained an act bearing upon this subject to be presented to congress. Dr. Gallagher moved that the report of Dr. Tucker be laid upon the table. Agreed to. A Warning. Dr. Tyler, of Washington, D.C., insisted upon the 234 dºſ [MAY 18, 1872. T H H C T.I.N.I.C. members exercising great care in submitting questions to congress, as all such subjects were likely to be governed by a ring for their personal advantage. That portion of the report of the committee which referred to taking action in connection with the authori- ties in Washington was stricken out, and the report was then agreed to. The Various Committees. The Committee on Nominations presented a final re- port, as follows:– Committee on Arrangements—Dr. J. B. Johnston, Dr. J. T. Hodges, Dr. J. S. Moore, Dr. Robinson, Dr. Ken- nard, Dr. Teste, Dr. Brokay, Dr. J. M. Scott, all of St. Louis. - Committee on Publication.—Dr. Atkinson, chairman, Pa.; Dr. D. Murray, Chester, Pa.; Dr. Wm. Lee, Dis- trict of Columbia; Dr. Caspar Wistar, Pa.; Dr. H. F. Askew, Delaware; Dr. A. Meigs, Pa. Committee on Prize Essays.--Dr. Moore, chairman, Missouri; Dr. Gregory, Missouri; Dr. Davis, Illinois; Dr. Parvin, Indiana; Dr. Mendenhall, Ohio. * Committee on Medical Education.—Dr. Carson, chair- man, Ohio; Dr. Tojan, Ga.; Dr. Howard, Md.; Dr. Steel, Col. ; Dr. Vanderpool, N. Y.; Dr. Johnson, Dis- trict of Columbia; Dr. Stout, Ga.; Dr. Welsh, Texas; Dr. Scott, Ark. ; Dr. Bailey, N. Y.; Dr. Jones, Ala.; Dr. McRuor, Me. ; Dr. Tally, S. C.; Dr. Blaine, N. J.; Dr. Shattuck, Mo.; Dr. Jasques, Va. Committee on Medical Literature.—Dr. Flint, chair- man, N.Y.; Dr. Yandell, Sr., Ky. ; Dr. Henderson, Ala.; Dr. Thrall, Ga.; Dr. Leary, Me. . Committee on Medical Necrology.—Dr. Jackson, chairman, Ky. ; Dr. Parsons, R. I. ; Dr. Hildreth, W. Va.; Dr. Johnson, D. C.; Dr. Simmons, Cal.; Dr. Wariner, Oregon; Dr. Stevens, Ohio; Dr. Agnew, Pa., and others. . - - OFFICERS OF SECTIONS. Chemistry and Materia Medica.--Dr. R. E. Rogers, chairman, Philadelphia; Dr. Ephraim, Cutter, Secre- tary, Boston. Practice of Medicine and Obstetrics.--Dr. D. A. O'Donnell, chairman, Baltimore; Dr. Benjamin F. Dawson, secretary, New York, Surgery and Anatomy.--Dr. Warner, chairman, Bal- timore; Dr. W. Peck, secretary, Iowa. Climatology and Epidemics.--Dr. George Sutton, chairman, Indiana; Dr. Elisha Harris, secretary, New York. g : Medical Jurisprudence, Hygiene and Physiology.— Dr. R. C. Busey, chairman, Washington; Dr. H. B. Arnold, secretary, Baltimore. : Psychology.—Dr. Isaac Ray, chairman, Philadelphia; Dr. John Curwin, secretary, Harrisburg. - The reported was accepted. A preamble and resolutions were presented and adopted declaring the Massachusetts Medical Society in full accord with the American Medical Association, upon which Dr. Bronson, in behalf of that society, tendered its thanks for the unanimity with which the preamble and resolutions were carried. Ethics—Exit Dr. Bliss. The Committee on Ethics presented their report, in which, among other things, the names of certain mem- bers were mentioned for exclusion for non-payment of dues; and also the same action in regard to Dr. D. W. Bliss, who is under sentence of expulsion from the society of D. C.; also, that alumni associations of med- ical colleges were not entitled to be represented in the association. The subject of the contracting for the sup- plying of medical attention by the year to every one other than charitable institutions was laid over. The Inevitable Contest. The question of the admission of females to positions as students and professors, in various medical institutions, was then referred to, and after a recital of the past action of the conventions on the subject, mention was made of the names of the Academy of Medi- |cine, of Washington, D. C.; the Freedmen’s Hos- pital, of Washington, D.C., and the medical depart- ment of the Howard Institution, as associations which had females among their practitioners, and had among their members unlicensed practitioners. The com- mittee recommended that the delegations from these in- stitutions be not, therefore, received in the present body. Dr. Rayburn, of the District of Columbia, one of the professors of Howard University, took the floor against the recommendation of the committee. He alleged that if the delegates referred to were kept out, they would be kept out because they were not in good stand- ing with the Washington Medical Association, and that that association licensed irregular practitioners, and also charged a fee for its license, against the legality of which there had been several judicial decisions. The Howard university, he said, received all who ap- plied for medical education, without distinction of color or of sex.' If the association see fit that institutions of that class shall not be represented, of course they have the power so to act, but, at the same time, it should consider well what it was doing before taking such a step. He thought that every human being should be allowed the right to the very highest development that God has made him capable of. - Dr. Busey, of Washington, followed him in the defense of the medical society of that city, and in favor of the . recommendation of the committee. He asserted that the society had never licensed irregular practitioners, or homeopathists, or any practitioner that had not pre- sented a diploma from some regular medical school, or passed an examination before the society's board. Dr. Rayburn, on the contrary, was a member of an institu- tion which did receive irregular practitioners. Dr. Parmer, of Washington, from the Howard Uni- versity, spoke on behalf of that institution. He denied MAY 18, 1872.] T EH. H. C. T.I.N.I c. ; 235 that there was a lady member of the faculty, but that a lady had been employed as ophthalmologist. He ac- knowledged, however, that the lady spoken of was ophthalmic surgeon of an institution in which certain members of the faculty of Howard University are in daily consultation. - At the conclusion of this address, a great deal of con- fusion was occasioned by crys of “question,” and by hisses from those who were anxious to vote without further discussion. . Dr. Parmer explained his position as professor in the Howard University. He said he had not practiced medicine in that city, and, therefore, had not procured a license, as the law requires. He did not understand why he should be excluded from this association on ac- count of his connection with that institution. . A very rambling and animated discussion followed, and the president had great difficulty in preserving order. Motions were made in rapid succession, but they were not noticed by the chairman. - * Dr. Sayre, of New York, moved that the resolution of the committee be adopted. - Dr. Todd seconded the motion, and, under the call of the previous question, it was finally carried by an over- whelming majority, whereupon the convention ad- journed. - - In the afternoon the various sections met as on the two previous days, for the consideration of medical and scientific subjects. - , The members subsequently repaired to the University |. of Pennsylvania to partake of an entertainment tendered them by the professors and graduates of that institution. In the evening, a lecture on Sound was given by Dr. F. Solis Cohen, at the Jefferson Medical College. The doctor illustrated his remärks by the use of various in- genious and delicate apparatus, showing in one case the waves of sound through the intervention of light thrown upon a mirror. The lecture room was crowded with the delegates and invited guests. After the lecture, a handsome entertainment was given to the members of the convention and their ladies by Col. Thomas A. Scott at his residence. - FRIDAY. The association convened in the same church and was called to order at the same hour by the President Dr. Yandell in the chair. - . . . . : Resolutions of regret were offered for the death of Dr. Zeno Pitcher of Detroit; Dr. W. W. Gerhard, Dr. Henry M. Dickson and Dr. Samuel Jackson, of Phila- delphia. - - - - - Dr. Porter, of Delaware, spoke on the resolutions, paying a high tribute to the memory of Dr. Gerhard. The resolutions were unanimously adopted by a standing VOte. A resolution providing that the Marine Hospital Service be placed upon the same footing as the medical department of the U. S. Army, was laid over until the next meeting. The reports of the various sections were presented, and without being read were referred to the Committee on Publication. - Reports were received from the following Special Committees, and referred without reading, to the Committee on Publication; On the Cultivation of the Cinchona Tree, Dr. L. J. Deal of Philadelphia, Chair- man; On the Structure of the White Blood Corpuscles, Dr. J. G. Richardson, Pa., Chairman; On Correspon- dence with State Medical Societies, Dr. N. S. Davis, Illinois, Chairman. - - Professor Gross offered an amendment to the by-laws, modifying the third section, so that instead of a report on Medical Education, or Medical Literature, or Cli- matology and epidemic diseases, there shall be annually delivered before the association, at its general meetings, an address on Medicine, one on Surgery, one on Mid- wifery, or the Diseases of Children, the lecturers to be appointed by the Committee on Nominations. Laid upon the table till the next annual meeting. Dr. Hartshorne offered a resolution, which among other things, recommended the appointment of a com- mission of experts by the Courts in all capital criminal cases where medical testimony is needed, instead of the present system of employing physicians as witnesses on opposite sides. Adopted. Dr. Askew, of Deleware, was appointed to prepare a series of resolutions expressing the feelings of the associ- ation upon the death of Professor Samuel Jackson. Resolutions of thanks were passed to the officers of public institutions, of the naval Station, and to the authorities and congregation of the First Reformed Presbyterian Church Association. Also, to the Com- mittee of Arrangements, medical profession, faculties and officers of the colleges, Colonel Thos. A. Scott, Dr. Wm. Pancoast and Dr. Hugh L. Hodge, and to the retiring President, Dr. D. W. Yandell. - - Dr. John Morris, of Baltimore, also moved that a vote of thanks be returned to the members of the press of Philadelphia, for their faithful attendance during the sessions. Adopted. - * - A resolution was introduced setting forth that the Association acknowledges the right of women to study and practice medicine and surgery in all the branches, but comdemns the public association of the sexes in mixed classes and clinics as subversive of true modesty and delicacy in both sexes. The consideration of the resolution was indefinitely postponed. The formal business of the Association being gone through with, the Chair addressed the convention in words of thanks for their support of him and his decis- ions during the sessions of the Association. He closed by hoping to meet all the members of the Association again on the other side of the Mississippi, at the next annual gathering. He then declared the Convention adjourned sine die. . - By the many trains which left the Reading Railroad | Depot during the afternoon, hundreds of the members 236 [MAY 18, 1872. T TH. H. cI.T. N. I c. of the Convention visited the Park, and amused and entertained themselves by driving to various parts of that section of the city, in lounging beneath the trees of the Belmont Mansion, and in partaking of temporary refreshments, preliminary to a collation which had been prepared for them in the pavillion. This part of the ceremonies of the day came off at 4 o'clock, and the delegates, their ladies and invited guests, passed a most delightful hour in the pleasurable business of partaking of the luxuries of the season—a fitting termination to a professional business reunion. At the close of the entertainment, addresses were made by John C. Cresson and John Welsh, Esqs. —-º-º-º- O R. I. G. I N A I, A R T I C L E S. sun-INvoluTroN of THE UTERUs witH. I DISP [, ACEMENT. BY PROF. THAD. A. REAMY. Clinical Lecture delivered at the Dispensary of the Medical College of Ohio. Reported by W. L. Beebe, [Member of the Class]. GENTLEMEN; This woman comes suffering, as she thinks, with pro- lapsus uteri. She will assume the recumbent posture on the left side. We will protect her by a sheet, and make digital examination. We find the cervix considerably enlarged, elongated and thrust back into the hollow of of the sacrum. The OS and intracervical walls, so far as I can reach the latter, present to the touch a high state of congestion, if not ulceration. Passing my finger into the post cervico-vaginal space, pressing up- ward I detect increased volume and weight indicating either retroflection, retroversion, or thickening of the lower segment of the post-uterine wall. From the direc- tion of the cervical axis, the OS being far back, it cannot be retroversion. Passing my finger into the anterior cul-de-sac I find a corresponding forward fulness, there- fore, I hardly think there exists retroflexion, but most likely abnormal enlargement of the entire uterus. This opinion is confirmed by the evidence elicited by conjoined manipulation with my left hand above the pubes. The uterine volume is clearly detected through the abdominal wall. I shall now introduce Simpson's sound which will settle the points of version, flexion, or enlargement. I have no hesitancy in introducing the sound on the ground of possible pregnancy; for this woman is nursing a child seven months old, and has not only menstruated four months past, but during the last period, just closed, the flow has been abundant, and continued two or three days beyond the usual time. I find by the sound there is no flexion or version; but the long diameter of the uterine cavity is nearly four inches. Each of you, gentlemen, may now make the digital touch and observe for yourselves the conditions to which your attention has been called. You will be as gentle and careful in your manipulations as possible, that no unnecessary irritation may be inflicted. This should ever be your rule in practice. And I am certain you will feel yourselves under special obligation to ob- serve it with this good woman, who has furnished you an opportunity for practical instruction, but not with- out sacrifice to her feelings. The patient will now be placed upon her back, the limbs flexed, nates brought to the verge of the couch; her person completely protected by this sheet which is perforated by an opening sufficient to admit the specu- lum. Allow me here, gentlemen, to ask you thus to prepare the sheet or covering for your patients when- ever it becomes your duty to employ this instrument, for it is neater and more thoroughly prevents exposure; which is no small argument in its favor. I trust that I address gentlemen who will fully appreciate all that is here implied, who will throughout their professional career feel themselves bound by the most sacred obliga- tions, under all circumstances, with the most tender Solicitude, to protect the delicate sensibilities of woman, and equally so whether you find her in the highest or humblest walks of life. The man who cannot scrupu- lously do this is utterly unworthy of such trusts as are committed to the physician. I use Cusco's bivalve modified by Mr. Autenrieth at my suggestion, being a little broader at the distal extremity than the ordinary pattern. For facility of introduction and range of vision, this style of speculum is in my judgment superior. You have now, gentlemen, a perfect view of the OS, cervix, and when I spread the blades wide asunder you can see considerable distance into the cervical canal. You have visual confirmation of the opinion arrived at by touch. The cervical walls are thickened, highly congested, the cervix elongated, lips slightly everted, muciparous glands enlarged, pouring out an abundant secretion, mucous membrane at en- trance of os in first stages of ulceration, vaginal walls re- laxed and greatly distended. - Now, gentlemen, before we announce the diagnosis, let us consider one or two facts in the history of this case. This patient is 34 yrs. of age ; seven months ago she gave birth to a child. At the completion of term, the uterus, which in the virgin state weighs but one and a half or two ounces has increased to several pounds; in dimensions, from one and a half to two inches longitudinal diameter to more than a foot. After de- livery as you know the uterus normally returns approx- MAY 18, 1872.] T ET H C T.INI c. 237 imately to its virgin dimensions. This process requires from fifty to eighty days, and is called involution. This woman informs us that necessity compelled her to arise from the lying-in bed within seven days after delivery. From then until now she has discharged all her household duties, including cooking, washing and ironing. What is the result 7 The diagnosis of this case? - Sub-Involution, The material constituting the growth which was essential during pregnancy has not been disposed of; there is sub-acute cervicitis, endometritis and corporeal inflammation. The uterine cavity is enlarged, the vaginal walls relaxed and distended, therefore, losing their power to grasp the cervix and sustain the uterus, whose increased weight demands more than ordinary support, more or less prolapsion must follow. Now you have an explanation of the pelvic weight, constipa- tion of the bowels, excessive menstruation, indeed all the depressing symptoms which torment this poor woman. She was correct in her opinion that prolapsus exists, nevertheless it exists to no very great degree, but in this, as in most cases of so-called prolapsus which come under our observation, change of structure in the vagina, uterus, or its appendages or in all of these, change consequent upon inflammation will be found as the principal pathological factor; and no treatment which does not clearly recognise this fact can be either rational or successful. I beg to remind you gentlemen, that simple displacement of the uterus, healthy and normal in size, in any direction including flexions, versions, or descent to a degree which will be likely to occur is a matter of no consequence. One moments reflection as to the weight, location, and normally free movable character of the organ must convince you of the Sound- ness of these principles. I cannot do better than to recommend to those of you who would be glad to study this subject at length the admirable work of Jas. Henry Bennett, M. D. on “In- flammation of the Uterus.” No man in my humble judgment, either home or foreign, has written upon this subject with more fairness and candor. And his argu- ments showing that inflammation usually precedes dis- placement, sustained by a large number of cases are unanswerable. It may not be improper for me to add, that in a large experience embracing several hundred cases which have been under my charge within the past twenty years, my observations made in the study and management of. many of these cases with special reference to solving correctly these very points of dis- pute among uterine pathologists fully sustain the doc- trine above announced. Again, therefore, gentlemen, let me impress upon you, that in the case before you, as in nineteen-twentieths of those you will meet in prac- tice, you should recognise chiefly inflammatory changes, Secondarily displacement. Treatment. I regret that this poor woman's circumstances are such that she cannot enjoy an almost indispensable ele- ment of success in curing her, viz., rest. You have al- ready learned that this woman within seven days after accouchment while the uterus was yet large and greatly increased in weight, its ligaments, pelvic fascia, and other minor means of support weakened, its chief sup- port, the vaginal walls, rendered almost useless by recent distension, resulting necessarily in the conditions we have found. Therefore need I say here, see to it that lying-in women under your charge remain in bed most of the time during three or four weeks after delivery; and in all cases where it is possible their exercise should be moderate during the first two or three months. If you will insist upon this course giving authority to your requests by an intelligent explanation to the patient and friends of the principles involved, you will be the means of averting a large per cent. of uterine disease and a vast deal of suffering. And permit me here to say, although not relevant to this case that every woman, married or single, who men- struates should observe comparative quiet during the flow. For there is not a pelvic structure which under- goes congestive changes during parturition, that does not undergo more or less change at each menstrual period. I beg you never underrate prophylaxis. The medical man who intelligently educates his patients to prevent diseases is a far greater blessing to humanity than he who is skillful in combating disease when it exists. But time will not allow further digressions. This woman must take all the rest possible. She will have injections into the rectum of cold water twice daily. Vaginal injections with warm water every night. Let the vaginal nozzle of the syringe be inserted so as to allow the stream to reach the cervix. The effect of this treatment continued for months, as it must be, will be quite marked, reducing the changes which have taken place in the vaginal walls and cervix. Within the cer- vical canal we shall insert a pledget of lint saturated with glycerine and tannin. I have derived benefit in similar cases from Ext. Pinus Canadensis. If relief to the cervix does not soon follow I shall apply a solution of nitrate of silver 8 to 15 grs. to 3.j. She is to have a saline cathartic twice a week. Iodide of potassium 20 grs. three times daily. In the course of a few weeks the iodide may be substituted by hydrarg bichloridi 1–16th to 1–10th gr. three times daily, to be continued two weeks then alternated with the iodide of potassium. If under this treatment decided improvement is not mani- fest, leeches should be applied to the cervix. I have seen the most rapid improvement follow their use, doubt- less dependent not alone upon the amount of blood ab- stracted, but largely upon the absorbent activity com- municated by nervous influence, direct and reflex as a result of their bite. In cases quite chronic when the 238 [MAY 18, 1872. TIEE C T , T N T C. vaginal walls are much relaxed benefit will follow the use of electricity. Pessaries. The practice so prevalent of using these appliances is not only contraindicated by the pathology of uterine displacements, but positively condemned by careful clinical observation. What good could follow pressing this inflamed uterus upward through the medium of the neck, also inflamed, and this by an instrument that must further distend the vaginal walls? - The Babcock pessary and others acting upon the same principle avoid vaginal distention, but they increase cervical inflammation and retard the cure. Intra- uterine pessaries are still more objectionable. $ I could only consent to the use of pessaries in Some rare cases of flexion and version, when all acute inflamma- tion has subsided, and in such cases the instrument should be worn temporarily; Hodge's double lever being best. In complete procidentia also when inflam- matory symptoms have subsided, the pessary may be employed as a palliative. - In conclusion (as we must examine other cases that are in waiting), allow me to assure you, suc- cess in the management of uterine inflammations and displacements either occurring in the virgin or married women will only crown the efforts of him who studies each individual case carefully and intelligently, and conducts his treatment accordingly. Time and perse- verence will accomplish great results. - —º-e-º---- DYSMENORREICEA. . Its Varieties and Nature. BY C. D. PALMER, M. D. There is a tendency in the medical mind to narrow the pathology of any disease to within the smallest pos- sible limits, for on such a simple basis the erection of a plan of treatment becomes correspondingly plain. The adoption of such opinions has often proved to be most incorrect on full investigation, and in practice pernicious. Views although narrow and one-sided, when advanced by men of marked ability and prominence, almost nec- essarily meet with a speedy endorsement and adoption on the part of the profession; it must be confessed, how- ever, to the decided injury of suffering humanity. In the study of no disease do we see the proof of the above remarks better illustrated than of dysmenorrhoea. In 1848, Simpson whose mind possessed a strong surgi- cal tendency, and whose mechanical abilities were of the highest order, recognising with Velpeau, the fre- uency of, and difficulty in the management of uterine h;, by the ordinary methods, re-introduced the use of the intra-uterine stem pessary. With what result subsequent experience and history have plainly told. In 1832, Mackentosh of England, conceiving the notion that all dysmemorrhoea was of mechanical origin, intro- duced the practice of dilating the uterine canal to over- come the seat of obstruction. Reporting on the practice he declared, that out of twenty-seven cases treated, twenty-four were cured; Of course his practice and reports largely influenced others. Our eminent country- man Sims, has for some time entertained similar views, laying it down “as an axiom that there can be no dys- menorrhoea, properly speaking, if the canal of the neck of the womb be straight and large enongh to permit the free passage of the menstrual blood.” And again, “dys- menorrhoea is simply a symptom to be found in some abnormal organic condition.” The originality, genius, and boldness and success of this distinguished gynae- cologist, have won to him a large school of ardent ad- mirers and followers. Not a few physicians to day coincide in the exclusive mechanical origin of dysmen- orrhoea. But, is all dysmenorrhoea mechanical ?, Most of the recent authorities in gynaecology have divided dysmen- orrhoea into at least four distinct varieties; the neural- gic, congestive, inflammatory and mechanical. Is there propriety in recognising in practice these varieties? That there is, abundant evidence is afforded by clinical observation and experience. . . - Neuralgia it is admitted on all sides, frequently affects various portions of the human system. There is no reason why so important organs as the uterus and ovaries, with such abundant nerve and blood-vessel organization, should not be similarly affected. And if so, most likely it would be at the very time of their greatest functional activity. Painful menstruation is induced by fatigue, mental and bodily depression, and various other causes operating upon the nervous system. Pelvic suffering is by no means uncommon of a severe kind, during the menstrual interim, from causes acting locally and capable of inducing neuralgia elsewhere. The time of occurrence of the pain in dysmenorrhoea in many cases argues its neuralgic nature. Commencing before the menstrual flux is established, often increas- ing in severity after that time, it continues though in a mitigated form till its close. . The flow does not relieve it. The state of the general health of the patient gives evidence of the nature of the menstrual suffering. Is she anaemic, and subject to neuralgia in other parts of the body ? If so, the presumption is, that the dysmen- orrhoea is neuralgic, especially if in a virgin in whom organic pelvic disease is comparatively uncommon. Here, there being a degree of immaturity and perhaps excitability of the sexual apparatus, the painful state is assumed by virtue of its special impressionability. The character of the pain is peculiar. Acute, lancin- ating, and although paroxysmal, still unlike the pain from the spasmodic contractions and bearing down efforts belonging to the obstructive form of the disease. The seat of pain may be either the ovarian or uterine region, or some distant part of the body. There is no evidence of organic pelvic disease on account of morbid symptoms in the menstrual interval, or determined by a local exploration. The uterine canal is sufficiently open and the flow is not clotted. - The seat of pain being the uterus or ovaries, has oc- casioned the terms uterime and ovarian neuralgic dysmen- orrhoea. But, as stated, the pain is not necessarily so limited, for it may attack the head, face, knee or toe. In the latter circumstance, its special location is not always uniformly the same. This is what is meant by systemic or constitutional dysmenorrhoea, the idea of which Sims has so much ridiculed. - Thus, the time, character and seat of menstrual pain, often become valuable elements in the diagnosis for de- terming the variety. Again, corroborative evidence is had in the marked * Sims' Uterine Surgery. . MAY 18, 1872.] TIH. H. C.I.I.INI c. 239 relief which is obtained by the use of anti-neuralgic treatment. The vast majority of cases occurring in virgins, through attention to the general health by proper hygiene, and by the steady administration during the menstrual interval of such remedies as iron, quinine, nux-vomica, arsenic and galvanism are effectually con- trolled. While again, and often, the use of such agents at the painful periods, as belladonna, bromide of potas- sium, gelsemium, cannabis indica, apiol and oxide of silver, remedies addressed to the nervous system, are attended with the most beneficial results. Certainly, if there was obstruction of an organic kind to the men- strual flux, these remedies would not prove curative. It would seem very reasonable then, to term this form of dysmenorrhoea neuralgic, and as Anstie correctly remarks, not on account of the circumstance of the men- strual discharge, but because it attends the process from an exaggerated irritability of the organs concerned.* It is usually thought that those who suffer from dysmenorrhoea are apt to be sterile. Such is true, when the disorder springs from a congested, inflamed state of the organs, or a distorted shape of the uterine canal, but needs proof when applied to the variety under con- sideration. On the other hand, the experience of many good observers would lead us to the opposite opinion. As to the production of pain in the congestive and inflammatory forms of the affection, little need be said. An organ in a healthy condition performs its function painlessly, quite unconsciously to the patient, but when inflamed the .* intense suffering may result. As an exemplification We have the pain of deglutition in pharyngitis, of digestion in gastritis, of defecation in rectitis. - Dysmenorrhoea resulting from the inflammatory affec- tions of the uterus, throw some light upon the location of that inflammation. As a rule, little or no pain at- tends menstruation when the cervix uteri is alone in- volved, either in its mucous or parenchymatous tissue, (for this portion of the organ does not take part directly in the menstrual changes)—provided the canal is normally well open, so that no stretching of the circu- lar fibres is provoked. - Fortunately for the patient, in cervicitis the canal is rendered patulous. - - Severe, and long continued dysmenorrhoea coming on gradually for days prior to menstruation, coupled with symptoms and signs of uterine inflammation, becomes strong presumptive evidence of corporeal implication. Very generally, the degree of suffering is in a direct ratio with the extension of the disease from the corpo- real mucous membrance to its parenchymatous sub- Stance. - Marked relief from pelvic pain attending uterine in- flammation sometimes follows a free menstrual dis- charge; evidently, on account of the local depletion in- duced. This symptom then, is valuable in diagnosis— and also as affording a good indication for treatment. It becomes a very easy matter to understand the mode of production of pain in ovulation when there is ovaritis. - - The uterus is not unfrequently the seat of rheuma- tism. Its special tissue organization leads us to the conclusion when we bear in mind the place of selec- tion of that disease. The many and decided cures which Dewees obtained by his tincture of guaiacum can be explained best in this way. Other anti-rheumatic reme- dies in appropriate cases act equally well. As to the so-called membranous variety of dysmen- orrhoea, the weight of opinion is that it has an ovarian origin. The changes in the uterus at the catamenial period in extent and kind, are wonderfully influenced by the condition of the ovaries. Witness the uterine changes in the decidual formation from the impregna- tion of an ovum exterior to that organ. So under the obedience of ovarian irritation, or inflammation, the uterus is mislead by the morborific influence. This view is advanced by Oldham, Tilt and others. ; Sir C. Locock well remarks, “from the supposition that the membrane is always expelled, and that it consists of coagulable lymph exuded from the lining of the uterus, necessarily resulting from inflammatory action, has arisen a very faulty opinion of the nature of the disease, and a most mistaken and pernicious mode of treatment when universally applied.” The existence of mechanical dysmenorrhoea remains no longer a doubt. The symptoms arising from the ob- struction are usually peculiar and enable the carefully inquiring physician to strongly suspect the return of the difficulty. Pain does not commence until the flow is established, increasing in severity in proportion to it, diminishing as it ceases—in fine, in any individual case existing in direct relation with the quantity of dis- charge. - The character of pain is intermittent or remittent, like the throes of labor, and is described as such by women who have gone through parturition. As often as the cavity of the womb fills with blood, contractions are provoked to overcome the obstruction and expel the contents. Until the organ is again refilled no pain is ex- perienced. The seat of pain is the uterine region. Here again the time, character, and seat of pain, are valuable symptoms in differentiation. Of course only a positive diagnosis is made out by a local examination. The determination of the presence of obstruction, though frequently a very easy point, as when arising from an elongated cervical cervix, cicatricial tissue, versions or flexions, still is not invariably so. This forces us to the conclusion, ever to be recognized, that mechanical dysmemorrhoea may not only be absolute but relative. Some standard then of normal calibre of the cervical canal must be established to determine. Dr. Tilt has ven- tured on this: “Where the cervical canal will not let an ordinary sound pass through it easily, the cervix should be dilated or divided.* Ever so patulous a canal may serve as an obstruction if the discharge is too freely formed in the corporeal cavity, or become clotted there from certain blood states, or inflammation of the mucous lining. Or, a canal considerably smaller than the average may afford no obstruction if the flow is scant and prolonged. To the mind of the author not a few instances of the so-called obstructive dysmemorrhoea, have their path- ology in a spasmodic state of the circular fibres of the cervix and the os-internum. The power of the inner os to contract is well seen in the difficulties met at times in attempting the introduction of the sound. In the healthy organ there is a closure here during the men- strual interval, a relaxation just prior to the coming period. The underlying pathological basis producing this spasm may be either a neuralgia of the uterus or ovaries, or congestion or inflammation of their organs. The degree of spasm, amount of obstruction and con- sequent pain vary at different periods, according to the amount of local difficulty. This mode of diseased action is found elsewhere. Vaginitis and vulvitis cause vaginismus. Neuralgia and inflammation of the rectum spasm of the sphyncters of that viscus. Very many cases of dysmemorrhoea have a mixed path- ology. This may be inferred partly from what has been stated, and appears more evident upon further consid- eration. - Thus the neuralgio, form may by virtue of extreme * Anstie—Neuralgia and its counterfeits. * Tilt's Uterine Therapeutics, 240 [MAY 18, 1872, TIEEE C T.I. NTI c. suffering in a patient with deterioration and depreciation of the general health, become complicated with the inflammatory element. Again the obstruction may be the primary link in the chain of disease of an indi- vidual case, which through retention of the menstrual fluid and consequent distension and excitement of the uterus to violent contractions, excite inflammation in the , mucous membrane and hyperaemia of the pa- renchyma. Still again, mucous inflammation may be the primary link, which inducing increased weight and bulk, gives rise to version and flexion, and thus the Secondary link or mechanical obstruction follow. In either of the two last instances, the neuralgic element may enter secondarily. The membranous presents the symptoms of the mechanical. In a certain sense, nearly all cases of dysmenorrhoea independent of congenital or acquired occlusion, strictures, distortions, are mechan- ical. The neuralgic is so rendered by the condition of spasm; the inflammatory by the presence of clots of blood, swollen mucous menbrane, displacements, te. But it should be borne in mind that the above mentioned varieties do entirely independently exist, or one of them at least, is sufficiently prominent to afford the necessary indications for proper management. . —º-e—sº- A C A D E M Y O F M E I DIC [ N E . vºm-º ºmºmº JAS. GRAHAM, M. D., PREST., L. WOLF, M. D., SECT. Transactions May 13, 1872. Reported by Joseph Ransohoff. DR. BARTHOLOW read a highly interesting paper upon the efficacy of paracentesis thoracis in the treat- ment of pleurisy with effusion, illustrating his re- marks by a series of cases. . DR. GRAHAM referred to those cases of this disease which he had been in the habit of describing as latent pleurisy. . In these cases the premonitory symptoms are not at all present, or only so to a slight degree, until effusion takes place. In the treatment of pleuritic effusions, he would occasionally succeed in slightly re- ducing the quantity of the effused liquid by means of hydragogue cathartics. In other cases this treatment was found entirely useless. He then related the case of a boy who had been sick for some time previous to the first examination. Upon physical exploration one-half of the cavity of the chest was found full of fluid. Treated the case with brisk hydragogues without any apparent absorption of the effused liquid. Paracentesis will be resorted to, with great probability of a cure. DR. MILLER presented several pathological specimens removed from a patient who had died of purpura hemor- rhagica. The subject was irregular in his habits, but in robust health until May 4th. Saw him for the first time on Thursday, and found him suffering greatly from dyspnoea. Observed a peculiar, offensive, cadaveric ador emanating from the patient. Upon examination, the entire trunk was found to possess a peculiar florescent hue, while red spots were observed in the left iliac region, and upon the arm. Some of these spots were also pustular. The patient complained of headache, and severe pain in the epigastric region. Later, on the same day, found the entire surface covered with this florescent hue, with here and there ecchymosed spots. These ecchymoses had also extended to the hands and feet. There was no hemorrhage from the mouth nor from the nose, although some had occurred from the bladder. The post-mortem examination was made nine hours after death. The lungs although of a very dark hue, presented no decidedly diseased condition. Found old pleuritic adhesions, and the sequelae of a previous attack of pneumonia. Upon section, the lungs presented a deep-red appearance, and the exudation of a bloody and frothy fluid. The right side of the heart was loaded with adipose tissue, while over its entire surface ecchymoses were visible. Some effusion was also present about the coronary arteries. The muscular tissue was healthy, and the valves were competent. The omentum was covered by a layer of adipose tissue, half an inch in thickness. The liver weighed five and a half pounds. The gall-bladder was entirely filled with gall-stones. The stomach was spotted upon its external surface, and ecchymoses were observed in the sub-mucous tissue, although no free blood was found in the cavity of the stomach. This condition was present along the whole extent of the intestinal canal. The pancreas was hard and indurated, but not hypertrophied. Free blood was found only in the kidneys and the bladder. The mucous membrance of the latter organ presented no mottled appearance. DR. MUSCROFT called attention to a case of Small-pox which had came under his charge. The eruption de- veloped itself in due time, and the case seemed to be a mild one. It soon, however, became confluent. During the duration of the disease, the patient was attacked by severe menorrhagia, which was arrested by means of aromatic sulphuric acid. Soon after the arrest of the uterine hemorrhage, indications of purpura became manifest. - The Dr. also made mention of two cases of peculiar hemorrhage in children, which had been sick with scarlet fever. In both cases, a small, conical tumor made its appearance upon one side of the neck. From the apex of this tumor a drop of blood exuded. In both instances fatal hemorrhage Supervened. DR. REAMY. remarked that he had seen many cases of purpura hemorrhagica in an epidemic of diptheria in 1857. He never knew of a well marked case, that recovered. DR. CLEVELAND stated that this case reminded him of one which he had seen one hour before the death of the patient. She had all the prodromic symptoms of small-pox. Ecchymosed patches were visible over the entire surface, and the conjunctiva was in an ecchy- mosed condition. There was slight epistaxis, and profuse hemorrhage from the uterus and vagina. No papular eruption was noticed. The diagnosis of hem- orrhagic small-pox seemed to be sustained, since six individuals who lived in the same locality were sub- sequently attacked by this disease. - - DR. C. P. JUDKINs reported one case of small-pox in which these petechia were visible 48 hours before the papular eruption appeared. We had seen several of these cases at the pest house during the present small- pox epidemic and this condition was not considered as a very unfavorable symptom as all such cases recovered. DR. LUDLow referred to a case of purpura hemor- rhagica in a child one year old which he treated with iron, turpentine and castor oil. This child made a good recovery. DR. MALEY presented a specimen which had been passed (per rectum) by a patient who had suffered intense pain in the region of the flexure. Referred to the section on morbid anatomy. º DR. LUDLow reports a case of procidentia Vesicº- The displaced viscus was replaced by the usual method, and retained in position by means of sponge, tampoºs- DR. 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I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMES A. FOSTEE, 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cincinnati, Ohio, or 172 Jef- ferson Avenue, Detroit, Mich- SAML. P. THOMAS T.A. I. I. O.R., DEALER IN English, French and Scotch GOODs, 34 West Fourth Street, ("Z.W’("A.W.W.??"A. William Autenrieth, ROBERT CLARKE & G0°S, No. 71 WEST sIXTH sº DEREET, BETWEEN WAINUT AND WINE, CINCINNATI, OHIO, MANUFACTURER OF AND DEALER IN |||}|| || || ||||||||| Abdominal Supporters, Trusses, CLUB-F00T SHOES, SPINAL APPARATUS, ETC Keeps constantly on hand a full variety of Metalic and Rubber Syringes, Storm.ach Pumps, Etc. STOCKINGS FOR WARICOSE WEINS, Special attention given to the fitting of Apparatus for Deformities. gº Agent for DR. L. A. BABCOCK'S Silver Uterine Supporter, —A LSO– DR. AHL's POROUS FELT SPLINTs, —A LSO– ID A Y *S SIPT, IN T S -AND- LIST OF NEW MHL iBTH in Mºulis Hill, GREEN'S PATHOLOGY AND MORBID ANATO MY, 8vo. Cloth. $2 5o DUCHENNE'S LOCALIZED ELECTRIZATION. 8vo. $3 oo DILLENBERGER ON WOMEN AND CHILDREN’S DIS- EASES. 12mo. $1 75 BENNETT ON PULMONORY CONSUMPTION. 8vo. $1 50 FIRST HELP IN ACCIDENTS. 12mo. $1 50 BEASLEY'S DRUGGIST RECEIPT BOOK. 8vo. $3 50 ECHEVERRIA ON EPILEPSY. 8vo. cloth. $5 od HOWE ON EMERGENCIES. 8vo. $3 oo HAMMOND ON NERVOUS DISEASES. 8vo. $5 oc RINDFLEISCH'S PATHOLOGICAL HISTOLOGY. $6 oo WARINGS’ PRACTICAL THERAPEUTICS, 2nd Am. Ed. 8vo. Cloth. $5 od Leather. $6 oo SCUDDER'S SPECIFIC MEDICATION. 12mo. Cloth. $2 5o TANNER'S HANDBOOK OF OBSTETRICS. 12mo. $2 oo WAN BUREN ON DISEASES OF THE RECTUM. 12mo. Cloth. $1 5o FLINT'S EXAMINATION OF URINE. 12mo. Cloth. $1 oo VOGEL ON DISEASES OF CHILDREN. 8vo. Cloth. $4 50 BEARD AND ROCKWELL’S MEDICAL AND SURGICAL ECECTRICITY. 8vo. Cloth. $4 50 ATTFIELD'S MEDICAL CHEMISTRY. 12mo. Cloth. $2.75 Leather. $3 25 BARTHOLOW’S HYPODERMIC MEDICATION. 12mo. Cloth. $1 5o TURNBULL's DISEASES OF THE EAR. 8vo. Cloth. $5 od TILT'S CHANGE OF LIFE. 8vo. Cloth. $5 oc NEUMANN'S HAND-BOOK OF SKIN DISEASES. 8vo. Cloth. $4 oo ANSTIE ON NEURALGIA. 8vo. Cloth. $3 oo. PANCOAST'S OPERATIVE SURGERY. 4to., with many plates. $1 o oo HOOD ON BONE SETTING. 12mo. $1 50 RINGER'S HAND-BOOK OF THERAPEUTICS. 8vo. $4 oo Holºs PARTURITION WITHOUT PAIN. 16mo. I OO PROCTER'S LIGHT SCIENCE FOR LEISURE HOURS. 12mo. $1 75 BERNARD's PHYSIOLOGY OF THE HEART: 50 cts. BARNES’ OBSTETRICAL OPERATIONS. 8vo. $4 5o NICHOL’S FIRESIDE SCIENCE. 12mo. $1 50. WOHLER'S MINERAL ANALYSIS. 12mo. Cloth. $3 oo PLATTNER'S MANUAL OF ANALYSIS WITH THE BLOWPIPE. 8vo. Cloth. $7 50 JEFFRIES ON THE EYE. 8vo. Cloth. $1 oo MANSFIELD, A THEORY OF SALTS. 8vo. Cloth. $4 oo JEFFRIES ON THE SKIN. 8vo. Cloth. $1 oo GARDENING FOR PROFIT. 12mo. Cloth. $1 50 PRACTICAL FLORICULTURE. 12mo. Cloth. $1 50 FULLER'S SMALL FRUIT CULTURE. 12mo. Cloth. $1 5o WOODWARD'S COUNTRY HOMES. 12mo. Cloth. $1 5o DARWIN'S ORIGIN OF SPECIES. 12mo. Cloth. $2 oo ARTHUR'S TREATMENT AND PREVENTION OF DE- CAY OF THE TEETH. 12mo. $1 50 TYNDALL ON LIGHT AND ELECTRICITY. 12mo. $1 25 THE AMATEUR MICROSCOPIST. Small 4to. . $1 75 Books IN PREPARATION. BRYANT'S PRACTICE OF SURGERY. BARNES ON DISEASES OF WOMEN. ROBERTS ON RENAL DISEASES. GUERSANT, SURGICAL DISEASES OF WOMEN AND CHILDREN. Medical, Scientific, and other Catologues sent on application. Any book in the above list sent by mail or express, free of charge on receipt of price. S. W. Elliott’s Saddle=bags 65 West 4th Street, Cincinnati, Ohio. WILSON BRO's. SHIRTS Made to order of N. Y. M. Muslin and 2300 HEAVY Linen, per dozen - - - $26 00 Wamsutta Muslin and 2100 HEAVY Lin- en, per dozen - - - - - - - - 33.00 Wamsutta Muslin and 1900 Linen, per doz. 30.00 Lonsdale Muslin and 1700 Linen, per doz. 27.0) First three qualities have ALL LINEN Cuffs and Neckbands. At above prices Cuffs are attached. Same quality of our own manufac- ture, ready-made, $3 per dozen less. Perfect satisfaction given or money cheerfully refunded. Also import and Manufacture Men’s Furnish- ing Goods. Pike's Opera-House, Fourth Street, Cincinnati; 931 Wabash Avenue, and 88 West Washington Street, Chicago. CALMA RG-CD MANUFACTURING COMPANY., MANUFACTURERS AND IMPORTERS OF AND Window Shades, 67 WºSz' Aſozºzºw Szºz', CINCINNXT, O, E. H. BRENEMAN, Proprietor, *W*AN'``ED—ACEN'`S. School Teachers, Students AND OTHERS, Can find light and healthful employment for the Summer, by engaging in the sale of our valuable and very popular works. One lady teacher just commencing work for us, reports her net profits for last week at Forry DoILARS-many others doing equally well. Large commissions or liberal salary as preferred. For particulars, address NETTLETON & CO., 161 Elm Street, CINCINNATI, OHIO: P. S.—We will make “special, TERMs” to medical stu- dents, who are “working their own way through college.” BASCOM & CARPENTER, Stationers, Printers -AND- Blank Book Manufacturers, 136 VINE sº DEREET, &\\\\\\\\\\\e E. D. ALBRO & BRO. IMPORTERS AND MANUFACTURESRS OF FOREIGN and DOMESTIC WOODS In Veneers, Boards and Plank, frtaint-Maºri', 'al-Builitaništait-Bitri'Wi. The only house in the Western country that saws Spanish and Mexi- can Cedar for Cigar-Box Makers. We import our own wood direct, and can sell at prices to compete with any and everybody. Also saw and keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. Office and Warerooms, 136 and 138 West Second Street, veneer Mill, 507, 509, 511, 513 & 515 W. Sixth St., CINCINNATI, ** 2 Sº- E- 7, Nºvi, S. º Zºº bº. Exc ---> -->g i$º |sº:º:s || º - *s | E CINCINN ATI. IET A C TU T., T Y . J A M E S G R A H A M, M. D., D E AN, Frofessor of the The ory and EPractice Of Medicine and Clinical Medicine. W. W. DAWSON, M.D., Professor of Principles and Practice of Surgery and Clinical Surgery C. D. PALMER, M.D., ROBERTS BARTHOLOW, M.D., Professor of Materia Medica and Therapeutics. W. H. GOBRECHT, M.D., Professor of Anatomy. P. S. CONNER, M.D., | Professor of Surgical Anatomy. $ JAMES T. WHITTAKER, M.D., I’rofessor of Physiology. SAMUEL NICKLES, M.D., Professor of Physics and Medical Chemistry W. W. SEELY, Professor of Medical and Surgical Diseases of Women. T. A. REAMY, M.D., I’rofessor of Obstetrics and Diseases of Children. JOHN L. CLEVELAND, M.D., Demonstrator of Anatomy. CHARLES KEARNS, M. D., Assistant to the Chair of Surgery IMC. D., I’rofessors of ID is eases O ſº the FCy e a n d HXar, and Secretary of the Faculty *~ T. LOUIS BRow N, M. D., Posecutor of Anatomy. *-*…* E. NOBLE, Janitor, College Building, Sixth St., bet. Vine and Race Printed and Published by Nor R1s & MURRY, Medical College of Ohio Building, Cincinnati. •º THE CLI g PUBLISHED EvKRY SATURfAY. TER M8–$2.00 a Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editor All Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer. Vol. 2. C IN C IN N ATI, -* No. 21. —w- º * £f M A Y 25, 1872. JAS. T. VV HIT TAKER, MI, D. Editor. No. 101 West Ninth Street, Cincinnati. TREASURER. W. W. SEELY, M. D., No. 118 West Seventh Street, Cincinnati. Printed and Published by THE CLIN1c. Publishing Company, *_e. C LU B R A T E S, sºmsºmºmº 4 Copies to one address...................................................... $ 7.00 6 & 4 “ ------------------------------------------------------ 10.00 12 & & & & - 18.00 O O N T E N T S. * — . • Page ORIGINALL ARTICLES GoITRE by Th. Sittle, M. D. * -----------....... ‘.241 ADENoMA by G. W. H. Kemper, M.D... 24.] TRANSLATIONs On the Employment of Electricity in Labor, by Dr. Tachard (Bull. Gen. de Therap., Mar. 30, '72.).................................................. 243 Contributions to the Pathology of Gunshot Wounds by Prof. Edwin' Rlebs (from the Allgem. Militärärztl. Zeit. April 14, '72.)....... 244 ACADEMY or MEDICINE || || || || || |||||||}, ! tºº, Hatiti Hālā; all lºſſ ºf Him, 92 FOURTH STREET, Opposite Post Office, CINCITSTINTA-TI, O-, & The Oldest Established Hat House on the Street. *Sã |Fine Silk Hats, Standard Quality $6,00. BoğAN ºbesiºsº º, túl Ill º, tº: Transactions May 20, "72. Uterine Fibroid—Specimen by Dr. Dandridge, Discussion by Drs. ICearney, Wright, Dawson, Reamy, Young, Carson—Syphilis, Cases by Drs. Reamy and Illowy—Cerebro-Spinal Méningitis, Cases by Drs. Orr and Maley–Stone by Dr. Buckner............. 246 SCIENTIFIC NOTES Lostorfer's Syphilis Corpuscles, War in Scientific Circles—Move- ments of the Membrana Tympani—Vivisections 248-249 NIELDHCAL NEWS The Opportunity of Menstruation—Relief for Baker Brown—Hom- oepathic Surgery—Fistula for Cystitis—Preventive Medicine.249-250 REVIEWS. The Treatment of Wenereal Disease by M. H. Henry M. D.—Lith- otomy and Lithotrity by Gurdon Buck, M. D.—Lectures on Aural Catarrh by Peter Allen M. D........................ ............250-251 C LINICAL, MIEMMORAN DA Intussusception, Novel Treatment—Intestinal Invagination— Galvanic Treatment of Bed-Sores 251-252 The range of electricity in therapy is widening daily. We publish a translation to-day announcing its utility in obstetrics. The germ theory of infection finds new advocates everywhere. Klebs, as is seen, proclaims the parasitic nature of pyaemia and Burdon Sanderson has just de- clared bacterians to be the characteristics by which we distinguish infective from non-infective inflammations; their number indicating the degree of infectiveness. The syphilis question, as it now stands, is still cold in comfort to that large class of ruminating bovines who J. TAFT, * * * * *=m, W. TAFT. Editor Dental Fegister J. & W. TAFT, TXTEINTTTSTS *: 17 WEST FOlº CINCIN IN • *s The Dentºs ºgisters A Monthly Journal, CONTAINING 48 PAGES, stolidly oppose every innovation. Devoted to the Interests of the Dental Profession, **- * N William Autenrieth, No. 71 WEST sIXTH sº IREET, BETWEEN WAINUT AND WINK, CINCINNATI, OHIO, MANUFACTURER OF AND DEALER IN |||}|| || || |||||||ſ, Abdominal Supporters, Trusses, CLUB-F00T SHOES, SPINAL APPARATUS, ETſ Keeps constantly on hand a full variety of Metalic and Fubber Syringes, Stomach Pumps, Etc., STOCKINGS FOR WARDGOSE WEDNS, Special attention given to the fitting of Apparatus for Deformities. Bay Agent for DR. L. A. BABCOCK'S Af rine Supporter, POROUS FELT SPLINTS, S PT, IN T S -AND- T) A Y * S *. ROBERT CLARKE & Co's. LIST OF NEW MHL intº in Mºllus inſ; GREEN'S PATHOLOGY AND MORBID ANATOMY, 8vo. Cloth. $2 50 DUCHENNE'S LOCALIZED ELECTRIZATION. 8vo. $3 oo DILLENBERGER ON WOMEN AND CHILDREN’S DIS- EASES. 12mo. $1 75 BENNETT ON PULMONORY consumpTION. 8vo. $1 50 FIRST HELP IN ACCIDENTS. 12mo. $1 50 BEASLEY'S DRUGGIST RECEIPT Book. 8vo. $3 50 ECHEVERRIA ON EPILEPSY., 8vo., Cloth. $5 od HOWE ON EMERGENCIES. 8vo. $3 oo HAMMOND ON NERVOUS DISEASES. 8vo. $5 oc RINDFLEISCH'S PATHOLOGICAL HISTOLOGY. $6 oo w WARINGS’ PRACTICAL THERAPEUTICS, 2nd Am. Ed. 8vo. Cloth. $5 od Leather. $6 oo SCUDDER'S SPECIFIC MEDICATION. 12mo. Cloth. $2 go TANNER'S HANDBOOK OF OBSTETRICS. 12mo. $2 oo WAN BUREN ON DISEASES OF THE RECTUM. 12mo. Cloth. $1 5o FLINT’S EXAMINATION OF URINE. 12mo, Cloth. $ 1 oo VOGEL ON DISEASES OF CHILDREN. 8vo. Cloth. $4 50 BEARD AND ROCKWELL’S MEDICAL AND SURGICAL ECECTRICITY. 8vo. Cloth. $4 50 ATTFIELD's MEDICAL CHEMISTRY. 1%mo. Cloth. $2.75 Leather. $3 25 BARTHOLOW’S HYPODERMIC MEDICATION. Cloth. $1 5o TURNBULL’S DISEASES OF THE EAR. 8vo. Cloth. $5 od TILT'S CHANGE OF LIFE. 8vo. Cloth. $5 oc NEUMANN'S HAND-BOOK OF SKIN DISEASES. Cloth. $4 oo ANSTIE ON NEURALGIA. 8vo. Cloth. $3 oo. PANCOAST'S OPERATIVE SURGERY. 4to., with many plates. $10 oo HOOD ON BONE SETTING. 12mo. $1 5o RINGER'S HAND-BOOK OF THERAPEUTICS. 8vo. $4 oo I 2.II) Oe 8vo. HOLBROOK.’S PARTURITION WITHOUT PAIN. 16mo. $1 oo PROCTER'S LIGHT SCIENCE FOR LEISURE HOURS. 12mo. $1 75 BERNARD’S PHYSIOLOGY OF THE HEART. 50 cts. BARNES’ OBSTETRICAL OPERATIONS. 8vo. $4 5o NICHOL’S FIRESIDE SCIENCE. 12mo. $1 5o. WOHLER'S MINERAL ANALYSIS. 12mo. Cloth. $3 oo PLATTNER'S MANUAL OF ANALYSIS WITH THE BLOWPIPE. 8vo. Cloth. $7 5o JEFFRIES ON THE EYE. 8vo. Cloth. $1 oo MANSFIELD, A THEORY OF SALTS. 8vo. Cloth. $4 oo JEFFRIES ON THE SKIN. 8vo. Cloth. $1 oo GARDENING FOR PROFIT. 12mo. Cloth. $1 50 PRACTICAL FLORICULTURE. 12mo. Cloth. $1 50 FULLER'S SMALL FRUIT CULTURE. 12mo. Cloth. $1 5o WOODWARD'S COUNTRY HOMES. 12mo. Cloth. $1 5o DARWIN'S ORIGIN OF SPECIES. 12mo. Cloth. $2 oo ARTHUR'S TREATMENT AND PREVENTION OF DE- CAY OF THE TEETH. 12mo. $1 5o TYND ALL ON LIGHT AND ELECTRICITY. THE AMATEUR MICROSCOPIST. Small 4to. BOOKS IN PREPARATION. BRYANT'S PRACTICE OF SURGERY. BARNES ON DISEASES OF WOMEN. ROBERTS ON RENAL DISEASES. GUERSANT, SURGICAL DISEASES OF WOMEN AND CHILDREN. Medical, Scientific, and other Catologues sent on application. Any book in the above list sent by mail or express, free of charge on receipt of Price. 12mo, $1 25 $1 75 S. W. Elliott’s Saddle=bags 65 West 4th Street, Cincinnati, Ohio. List of Pharmaceutical Preparations, MANUEACTURED BY Jø/ZW WºZºZ & AER07///º, FEº,4ADrººl: I.A. ——dº ELIX, PHOS, IRON, QUININE AND STRYCHNIA, ELIXIR OF GENTIAN FERRATED, ELIXIR, WALERIANATE OF AMMONIA, (Goddardi’s Formula,) ELIXIR VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, Iron, with Phosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Iron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK, *~ ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER WINE OF IRON, Citrate of Iron and Peruvian Bark, FERRATED CORDIAL ELIXIR, ELIXIR CALISAYA BARK, WINE AND BISMUTH, ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, * FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, TASTELESS COD LIVER OIL, TASTELESS COD LIVER OIL. FERRATED, BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and sherry wine, ELIXIRVALERIANATE OF STRYCHNIA, WINE OF PEPSIN SYRUPSUPERPHOSPHATE OF IRON, J ELIXIR OF BISMUTH, COMP. FLUIDEXT, BUCHU AND PAREIRA BRAWA. STUTEPI POSITOTERIES. Bectum, Vaginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great eare, and of every variety of combination. Lists sent on application. SPONGE TENTS.—For the Urethra, of every size and style, made of finest quality of sponge. --~~ º -*-*- § E; Eſ ||||, 3 |. º º º t . ſ -i- -- --- sºsº. - Šºš º: sº §§§ | | | º * iºni - | #. |# i. Zºº: Xº § § # | | |ºil # | ºffilii ń. "ſº tº Tºº º | ill º iſſuium ſ | kill uſuiſing lºsſ #|| É º II. ſlips Fºº- ..ºs ºf # = º ſº ... : : º - -- **A* - º º:4 Sº ޺ Z4%22 š% cº- P- %% Eºs sº * Ż - N EHOSE’ITAT1. The GOOD SAMARITAN HOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner of Sixth and Lock streets. It is handsomely furnished thr pointments of a First-class Hospital. halls and abundant windows secure that full and fr Service is furnished by the U have sacrificed their lives to such purpose know how to afford. oughout, and is provided with all the necessary ap" Porticoes, with commanding views, surround the whole house, and wide ee ventilation which is so essential to health and comfort. sISTERS OF CHARITY, * nder the Superintendence of the well-known SISTER ANTHONY, with that care and attention which only they who The regular Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each Professor presiding over hi of the city any physician of their choice. The GOOD SAMARITAN HOSPITAL presents extra inducements to Invalids throu m in any case of protracted illness, or in cases, more particularly, requiring Surgical Operation, where quiet asylu s own especial department. Patients may, however, select from the regular profession ghout the State as a safe and some stay is necessary in after treatment. Rooms vary in price, general service. Bºy" Address, according to the character of appointments necessary and service required, ranging, in terms, between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand of $. SISTEER ANTHONY, FIospital of the Good Samaritan, Corner of Siacth and Lock Sts., Cincinna” Ohio. Wm. Wilson McGrew, ºvo. 27 was r Fovrra Srwºrr, PIKE'S OPERA, HOUSE BUILDING, Importer and Dealer Diamond and Gold Jewelry, Watches for Ladies and Gentlemen, Sterling Silver Tableware, Bronzes, Antique and Modern; Marble and Bronze Clocks, Marble Statuary, FAN cºr Coons, G E N E R A L.L.Y. DIVIDED MEDICINES, The Divided Medicine Com’y, CINCINNATI, OHIO. —c-O-O- The Company have the honor of bringing to the notice of the Profession, this NEW AND ExcEEDINGLY PRACTICAI, METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. ; The Divided Medicines are prepared by FREDERICK KRAUs, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MORE. The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every Square will consequently contain accurately measured quantities. But not only SoLUBLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINES. gº. | * This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain; ; : *, *, *, and even idoo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. | Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE TO SPoſL BY ANY LENGTH of TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. & Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calls with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. g For Samples, Price Lists, and Agencies, address sees, Or FRFDERICK KRAUS, Chemist and Druggist, Walnut Hills, Cincinnati, O. MR. Fr.EDERycK KRAUs: CINCINNATI, February 15, 1871. Dear Sir—The specimens of your “Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: SULPH:MORPHII.......................% grain in each square. ARSEN:ACID..........................1-20 grain in each square. ** OH IN INI ....................... I & 6 é & 66 CALOMEL 34 “ 66 $6 “. COPPER ....................... % *. $6 RESPECTFULLY Youns, * E. S. WAYNE, Analytic Chemist. T TEI IED CT I I INTI C. 241 Vol. 2.] S A T U R D A Y, M A Y 25, 1872. [No. 21. O R. I.G IN A L A R T I C L E S. –-º-º-º- G O IT R. E. The Treatment of a Case by the Method of Lucke (Bonn ). BY TH. SITTEL., M. D. Cincinnati, Annie M–, Riverside, O., aet. 17, is a daughter in a family in which any affection of the thyroid gland has hitherto never been observed. The first signs of hyper- trophy in the patient, according to the mother's report, manifested in her earliest childhood. It is only in the past year, however, that its greatest development in volume has been observed, and this increase is remarked to stand in close connection with menstruation which established itselfin her sixteenth year, and is occasionally quite profuse. Four years ago she entered the convent of the Sisters of the Good Shepherd, where about the middle of last year she passed into my hands for treatment. I adopted in this'patient my usual plan in these cases, namely, the iodide of potassium in medium doses, internally and ex- ternally the application of the tincture of iodine. The result, however, was only negative. She was then kept under the full influence of iodine for a considerable length of time but with as little benefit. I then commenced the treatment as recommended by Lücke (Die Chirurgische Behandlung des Kropfes, A. Lücke, Volkmann's Sammlung Klinischer Vorträge, Leipsic, 1870), which consists in the injection into the tumor of the tincture of iodine. When this treatment was commenced the tumor measured twenty-one and one-fourth inches in circum- ference. The first injectien into its parenchyma was made Jan. 17. Ten drops of the alcoholic solution of iodine in the proportion of one to ten were thrown in. The second injection was made Jan. 27, twelve drops; the third, Feb. 5, thirteen drops. From this time the diminution commenced. The enlarged lateral portions, and more especially the indurated median portion, which was so increased in size as to be suspended over the incisura sterni, became completely softened, though the injections were made only into the sides. With the disappearance of induration and diminution of size vanished the difficulty of respiration which had been the constant and distressing attendant of its manifestations of reaction were slight. growth. Directly after the third injection the tumor measured only 18% inches circumference, [2} in. less]. The fourth injection was made February 12, 15 drops; the fifth February 23, 20 drops. At this time the measurement was 18+ inches. Up to this period local A few days after the fifth injection there was an unpleasant taste of iodine; this, however, soon disappeared. Further injections were made as follows:—sixth, March 2, 22 drops; seventh, March 11, 25 drops; eighth, March 26, 25 drops. Measurement now 18 inches. The flinth injection was made April 10, 25 drops; tenth, April 17, 25 drops; eleventh, April 24, 25 drops. Measurement previous to last injection 17 inches. The tumor has now been reduced by eleven injections four and one-fifth, inches and its steady and constant decrease is evidence of the efficacacy of treatment and is promise of future perfect success. The digital compression after removal of the syringe and the closure of the wound of penetration by adhesive plaster as recommended by Lücke were always relig- iously observed. The suggestion, too, was adopted of permitting the needle to remain in the tumor while the body of the syringe was withdrawn to be refilled that there might be the least possible danger of injecting the iodine into a minute vein. The almost entire absence of local reaction was probably due to the fact that cold dressings were always applied to the surface after each injection. I may add in conclusion that this patient with the plan of treatment stated was exhibited to the class in the clinic of Prof. Dawson at the Good Samaritan Hospital. —º-e -º- A D E N O M A . BY G. W. H. KEMPER, M. D. Muncie, Indiana, Dr. John C. Helm, a prominent physician of our city consulted me in regard to an unusual symptom presented in his own case, Dec. 20, 1871. Dr. H. was in his 60th year. Has practiced medicine in several localities for a period of about forty years. About twenty years since he had a severe and prolonged attack of erysipelas contracted by infection from a cadaver. This attack led to swelling and suppuration of the axillary glands of one side, terminating in abscess, followed by tedious convalescence. No other glands were involved. From that time he has been prone to traumatic erysipelas. His general health, however, was good until about two years ago, when he was prostrated suddenly while at Indianapolis, probably as a result of malarial poisoning. His convalescence from this attack was quite tedious, indeed, he has never recovered his usual health since. On the 28th of November last, he was called to 242 [MAY 25, 1872. TIEEE CI.INI c. attend a boy who had received a severe injury from machinery; a large mass of flesh having being torn from his arm. The treatment of this wound required his presence twice daily. Some sloughing attended the healing process, but it maintained a healthy course to the date of recovery. At some time near the first of December, while removing some of the sloughs, he pricked his left hand with the scissors, but this led to no irritation or uneasiness. At the date mentioned, when I saw him, the most prominent symptom was enlargement of the lymphatic glands of the cervical, axillary and inguinal regions. He informed me that this enlargement began about December 13, and that the first glands to enlarge were the inguinal. Some of the glands were as large as pullett's eggs; others but slightly increased. All had a semi-solid feel, and were painless unless firmly pressed. There was never any discoloration of the skin over the glands. Simultaneously with the glandular trouble his health began to decline. The spleen was not enlarged, no anasarca, anorexia, bowels regular, tongue clean, temperature normal, oc- casional excessive sweatings, sleeplessness, sense of de- bility. R. Iodide of ammonium internally and exter- nally, and general tonic treatment. * - January 13. The glandsgenerally are smaller. About one week since, at Dr. Helm's request, I wrote to Dr. Parvin to meet mein consultation, stating that I regarded the case as one of adenia. Dr. Parvin came to-day. He regarded the disease as an anomalous one, and favored the view which I will state, was held by Dr. Helm him- self, that his symptoms were due to the absorption of infectious matter from the wound made by the scissors. He gave a favorable prognosis and favored a continua- tion of the treatment. Jan. 28. The cervical glands nearly reduced to normal size. One in right axilla is still quite large. Inguinal glands smaller. Appetite better. Sleeps better, and feels stronger. . Feb. 4. The cervical glands are again enlarged. One in right axilla still large. During the past week he attended a few patients. Feb. 16. Since last date has had two attacks of diarrhoea, which were, however, readily controlled by remedies. A large number of the glands are still enlarged. He has been confined to his room for the last few days. For several days past he has had diurnal paroxysms of fever, Still subject to the periods of excessive sweating, mostly confined to face and head. The sweating has no relation to the fever. He complains of a sense of oppression about the middle of the sternum, causing some difficulty of breathing. Physical signs reveal large mucous rales in the spot indicated, as well as superior lobe of right lung. Expectoration not profuse, of a rather tenacious mucus. At the suggestion of my friend Dr. Carson, of Cincinnati, he has been using cod- liver oil and arsenic for some time past. March 11. Dr. Winans became associated with me | of infection. in the case on the 8th, and to-day Drs. Todd and Bigelow, of Indianapolis, arrived and consulted with us in regard to the case. The latter gentlemen were unwilling to admit the evidence sufficient to pronounce the disease true adenia, but rather regarded his case as one of debility and prostration. They gave a favorable prog- nosis and concurred in a tonic plan of treatment. April 7. For a week past he has suffered from aphonia, merely whispering his communications. An eczematous eruption of the right nostril appeared three weeks ago, and has manifested no disposition to heal in spite of remedies. - * > At this 9 A. M., we found him much worse. He had passed a restless night, unable to lie down for one moment. His countenance presented an anxious ap- pearance. His hands were livid for the first time. Res- piration was somewhat difficult. At his own request we agreed to meet him again at 1:30 P. M. Shortly after our departure his symptoms assumed a more alarming aspect. At 1:15 P.M., I found him much worse. Pulse feeble, general lividity, inability to recognize his friends, and increased dyspnoea. Stimulants were administered at once. Dr. Winans soon arrived and concurred in the opinion that the symp- toms indicated approaching dissolution. Stimulants partially revived him, but consciousness never returned. He continued in this condition until the morning of the 8th day of April, when he died. The duration of his sickness was about four months. No post-mortem was made. The emaciation was strongly marked. From the time I first saw him, until his death, there were periods of apparent improvement, but averaging the whole period the descent was gradual and progressive. - The symptoms of his disease did not resemble those of a poisoned wound, for as before stated, while the prick was received on the left hand, the inguinal glands were the first to enlarge, being altogether out of the line Again, the glands were of very large size, and semi-solid consistence with no tendency to sup- purate or even become tender, exactly the reverse of glandular enlargements caused by infectious matter. Another peculiarity of his glands was the alternation or succession in their increase and decrease of size. Such is the history and termination of one of a class of cases, of which Virchow Iemarks: “In the histories of all the known cases of leukaemia we only find it once as yet recorded that the patient, after he had been for some time the subject of medical treatment, left the hospital considerably improved in health. In all the other cases the result was death.” —sº-º-º- CHOLERA IN RUSSIA.—Cholera has just (Apr. 13) broken out in Kamionka with such violence as to carry off 21 people in this little village of but 150 souls. This village last year escaped attacks while the disease raged throughout all the surrounding country. º MAY 25, 1872.] TIH. H. C.I.I.INI c. 243 oN THE EMPLoyMENT of ELECTRICITY To - FAGILITATE LABort. - An Abstract from a Thesis entitled “De l'electricité appliqûe a l'art des accouchments,” by Dr. Tachard, Externe de la Maternité, etc. Paris, 1871 [From the Bulletin Gen. de. Therap., Mar. 30, 1872]. The applications of electricity in medical and surgical practice play a daily role in the treatment of the most diverse affections. Obstetrics, with the other branches of surgery has been made the field of experimentation. M. de Saint Germain in his article on the use of elec- tricity in labor,” after stating existing knowledge on this subject, gives the results of his experiments on the effects of electricity on parturition. These results have been verified by the late investigations of his pupil Dr. Tachard, who has written upon this subject his in: augural thesis. . . . . - - - According to the results of experimentation the in- terrupted or induced currents are the most appropriate for the excitation of uterine contraction. If the voltaic battery be employed the current must be broken. The induction apparatus of Ruhmkorff or that of Clark pro- duces the same results as they furnish an interrupted current. - ... • - - In his experiments, Saint Germain used by preference the apparatus of Ruhmkorff employing the electric cur- rent of the telegraph which connects the hospital Cochin with the pavillion of the Maternité. This current was interrupted by a trembleur, and one of the poles was placed in a vase of water that the intensity of the cur- rent might be modified according to the susceptibility of the patient, excitability of the uterus, etc. This facility of graduating and suppressing the current at will, makes of electricity an agent superior to all other oxytoccics, as e. g., the ergot of rye. - The method of application the least fatiguing to the patient and the most convenient for the accoucheur is that which has been adopted by Barnes in England and Saint Germain in France. • * * - It consists in bringing the two poles in contact with the abdominal walls at the level of and on each side of the umbilicus. The foetus manifests by its very active movements its sensibility to the current. At the maternité Cochin, Tachard applied around the abdomen of the accouchee an elastic girdle provided on each side with a brass button to which the reophores were respectively attached. To make the contact more effective he interposed a sponge saturated with salt water between each plate and the abdominal wall. The observations reported by M. Tachard are twenty- two in number. First he cites three observations of Frank. In the first, a primipara of forty years of age, though the efficacy of the current was incontestable, * Noveau Dictionnaire de médicine et de chirurgie pratiques, Vol. xii, p. 556 et seq. • . intensity. still it became necessary to terminate labor with the forceps. The second was a case of complete success, the third a failure. - Then follow the nineteen observations collected by the author, cases taken from the inmates of the maternité hap hazard [au hasard]. Of these cases we publish only the first in illustration of the action of electricity on the course of labor. Of the twenty-two trials, thirteen were cases of complete success, four of failure; in the remain- ing five cases though the action of electricity was mani- fest yet it was not sufficient to conduct the labor to a happy termination. Victorine Marty, aet. 27, primipara, entered May 20, 1870. Pelvis normal, cervix completely effaced, os per- mits the introduction of the finger. Cephalic presenta- tion. Since May 20, feeble pains have been present at long intervals. On *.* they increased a little in At 8% P. M. the pains gradually disappearing, becoming more and more infrequent, the os being about 3 cent. diameter I applied the electric current for twenty minutes. Uterine contraction was excited immediately; the pains produced followed each other rapidly. At 10 o'clock the second application was made. From this time on the pains succeeded each other rapidly and forcibly. Labor advanced regularly. At half past 11 there was spontaneous rupture of the membranes; at 1 o'clock expulsion of a living child in good condition. In five minutes more delivery was complete. This patient was of lymphatic constitution and quite feeble. These patients in general, the author remarks, bear electricity well. An intense current is not necessary to produce good effects. Again, the duration of the faradaic séances is never long enough to induce irrita- tion of the skin at the point of contact of the poles; at least the author has never yet observed a case in which the least accident of any kind occurred. The action of electricity in labor is given en resumé at the end of the thesis in the following conclusions which we reproduce and which, we may add, are in accord with those appended to the paper of Saint Germain. - 1. In no case were uterine contractions induced where they had not previously manifested spontaneously. 2. In every instance in which labor had commenced and the pains had progressed regularly and periodically, whenever we applied the two poles at the lumbar region we remarked in a very short time the manifestation of a new activity in the contractions and shorter periods of interval. 3. We have likewise observed that all the contrac- tions produced or provoked by electricity were much longer and much more painful than the contractions of spontaneous origin. - 4. The dilatation of the os always seemed to increase with rapidity. 5. In all the cases hitherto observed the expulsion of the placenta followed immediately upon expulsion of the child. 6. In no case did the child suffer in any way from the electric action. The same we may say for the mother, 244 [MAY 25, 1872. T EIHL c 1 INTI c. Tachard adds that during the period of expulsion electricity always seemed inutile in awakening uterine action when the inertia occurred just at this period At the end of the thesis are three short chapters also very interesting but containing, unfortunately, but few facts and conclusions, which we here append. 1. Electricity in Puerperal Hemorrhage. The observa- tions of Randfort,” Dorrington,f and Mackenzief seem to prove the efficacy of electricity in the control of uterine hemorrhage. Puerperal hemorrhage, however, is an accident so rapidly fatal at times that re- liance may not be placed on this means alone. It is best in these cases to use simultaneously electricity and ergot. The author has not had the opportunity to make any personal observations on puerperal hemor- rhages as it rarely occurs in the service of Saint Ger- main because of his practice, the author thinks, of ad- ministering to every accouchée immediately after labor |infectious condition without any localization. This 2 grm. of ergot. (See the thesis of Dr. Bureau, 1870). 2. Electricity in Induction of Premature Labor. Dorrington (loc. cit.) reports one successful case; Barnes two cases of success but he took the precaution of rupturing the membranes before the electricity was applied. P. Dubois, Saint Germain and Tachard have all failed in this procedure. 3. Electricity in Extra-Uterine Pregnancy. M. Buici, Professor at the University of Pisa reports a case of extra-uterine pregnancy in which he succeeded, by the aid of a single application of electro-puncture in arrest- ing the development of the ovum. All the morbid symptoms disappeared, the tumor shrivelled, reducing to the size of a pigeon's egg, menstruation was re- established and the patient was saved. (Gazetta med. Italiana, 1857). En resumé, the author believes that electricity may be called to the aid of the accoucher: 1. In labor during the period of cervical dilatation whenever there is uterine inertia. 2. During delivery when the placenta is retained within the womb. 3. In extra-uterine pregnancy as a means of aborting foetal growth. It seems appropriate here to remind our readers again of the memoire of Dr. S. Iffla presented to the medical association of Victoria (Australia) and analysed in a previous issue of our paper [See also THE CLINIC vol. II, No. 5, p. 60]. In this memoire Iffla reports cases in which he has obtained good effects in the treatment of the intractable vomitings of pregnancy by the appli- cation of the continuous current to the epigastrium. MEDICAL STUDENYS AT VIENNA.—Fourteen hundred and seventy-one medical students are registered in the summer session of the Vienna school. Of these 506 are Hungarians. ,-- * Lond. Med. Gaz’, 1846. f do do ! Barnes, The Lancet, 1853, Bull. Gen. de Therap., V. XLVII, p. 48. contriburroNs to THE PATHological ANAToMY or GUNSHoT wounds. From Observations in the Military Hospitals of Carlsruhe, 1870--71. By I’RoR. EDWIN KLEBs, (BERNE). From the Allgemeine Militärärztlicihe Zeitung, April 14, '72. Pyaamia is usually distinguished from scepticaemia by the fact that in the former secondary purulent de- posits are encountered in the lungs and other parts of the body while in the latter there is present a febrile, view is not tenable, however, for there are processes which are considered as purely septic during life while on post-mortem, secondary pus formations are encount- ered in the internal organs. As to the disturbance which the entrance of pus into the blood excites it is believed on the one hand that the pus acts mechanically (embolism) and on the other, chemically (phlogogenous effects). Under this chemical action, again, two distinctions are made accord- ing as the phenomena are attended with transitory or continued fever. In reference to these differences in the action of pus it becomes a question whether it is the pus as such or some substance mingled with or con- tained in the pus which exercises these deleterious in- fluences. Microscopic investigation has taught us that these changes depend upon the presence of the parasites of decomposition which the author designates microsporon 8epticum. The author now brings forward the proofs of his view, and exhibits the extension of the microsporon Septicum, 1st, in the fluids of wounds. These parasites are found in laudable pus though difficult of detection as well as in the thinner, unhealthy fluid where they are in rich abundance. They present in the form of staff-shaped bodies (bacteriae) motionless, not seldom arranged in series; further as numerous brilliant microsporons, ex- tremely minute ($ micromill.) bodies, lying free, when they exhibit oscillatory motion or accumulated in groups (like zooglea) or finally arranged in rosicrucial threads. - 2nd. The author considers their occurrence upon the surfaces of tissues. - - In man he has observed these microsporons upon the following surfaces; on granulating wounds, as well of old abscesses as of fistulous canals and serous mem- branes. The deposition of these spores is clearly dependent upon the condition of the tissue surface; an excess of dryness or of moisture being alike unfavorable to their development. The author has never observed them on MAY 25, 1872.] T EH. H. C. T., IIST.I. C. 245 dead bone or cartilage fragments nor upon richly ex- uberant and excessively moist granulations. He con- siders the septic parasite to be perfectly distinct from the parasite of tooth caries as this parasite is colored blue by iodine while the spores of Septic parasites remain uncolored. z - The inplantation upon cartilaginous surfaces occurs after the solution of their upper surfaces, zoogloea develop in the depressions and the process advances further and further, ceasing only when it is mechanically checked by folds of tissue or apposition of articular sur- faces. Dead fragments or surfaces of joints do not offer a suitable soil for the development of parasites. On granulating surfaces Klebs has been best able to follow their development in those cases in which a so- called pyogenic membrane, composed partly of pus cells, partly of fibrine, was present. There is observed a solu- tion of the superficial layers of tissue whose reticulae are opened by the penetrating masses of zoogloea, then follows the erosion of the bloodvessels. * On the larger granulating surfaces the regions where the microscoporon Septicum exuberates to induce the destruction of tissue are recognized by the existence of small, round cavities in the superficial layer of fibrin which easily bleed. The parasites are found more especially wherever there are narrow cavities whose con- tents are subjected to light pressure, and are not removed by the cleansing stream of water. . It is probable that the microsporon occurs also on serous surfaces, though the author has had no oppor- tunity of demonstrating it directly. This much he is able to state, however, from the observation of one case that the microspores from the purulent accumulations in the vicinity of serous cavities penetrate through the tissues ânto these cavities, and once arrived here they may excite, even after the subsidence of all local irritation, new inflam- mations and suppurations. On the dissemination of the miccosporon septicum in the internal organs the author expresses himself as follows: The parasite induces a destruction of tissue on every surface on which it exuberates and it depends on the condition of the tissue whether or not penetration into the blood and lymph vessels is possible. Penetra- tion into bloodvessels he was able to demonstrate accurately in one case. The tissue layers of the blood- vessel are destroyed from without inwards while the parasite pushes its development inwards. Even before the intima is entirely desroyed, the parasites penetrate into the mass of the blood and induce a coagulation which remains adherent to the vessel walls or fills the entire calibre of the tube. In advancing destruction, secondary later tertiary (fatal) hemorrhages occur. In all these cases the penetration of the parasites is the precursor and the subsequent ligations are of as little effect as the subsequent amputations ...In bones, tendons and other resistent tissues the para- sites do not at all enter the blood or at least only with Gifficulty; on the other hand, penetration is facilitated by ingress of the parasites into the marrow. * | Immigration always takes place from the surface of the wound as the course of numerous hæmatoidin cells clearly shows. These cells which contain haematoidin may be followed into the lymph glands. They may also become carriers of the parasites and excite suppuration at a distance from the wound. - In a few cases Klebs was able to demonstrate micro- spores in thrombi developed behind the valves in veins and though these microspores did not directly excite coagulation yet they effected such changes in the vessel walls as to render them excitants. Next is considered the metastases of the lungs. The author exhibits that the necessary connection between thrombosis, embolism and suppuration is not yet fully explained. Venous thromboses may occur in the lungs without suppuration and they may again be absent when wedge shaped abscesses are present. Pulmonary metastases, therefore, are not to be explained as thrombi and emboli. They may originate in this way, may not. - Virchow's explanation of this condition, thus, seems considerably strained while the view of a septic infec- tion reconciles all contradictions and explains all cases. In fact, the author was able to demonstrate in a series of cases, in which pulmonary metastases could not be derived from thrombi, the importation of parasites into the vessels of the lungs. A series of cases of diffuse pneumonia which could not be derived from emboli and which exhibited in their anatomi- cal changes important differences from the usual forms of pneumonia, the author demonstrates to stand in connection with parasitic exuberations and considers these pneumonias as produced by this cause. - As to abscesses of the liver, he says that they, with few exceptions, do not possess the character of embolisms, and after expressing the different views as to their development he states that they, too, originate from para- sitic processes. The spores of the microscoporon develop in the capillary system, fill these vessels to distension when de- struction of the hepatic cells and parenchyma follows. These spores are then crowded over into the branches of the vena porta and hepatie veins and pass from one lobe to another. Concerning the course of the Septic mycosis, Klebs says that it is perfectly typical and in the more acute cases, a period of ten days suffices for the development of parasites in the different regions of the injured part, in the lungs and the organs of the systemic circulation. Renewal of these processes may occur later as already indicated. - As this mycosis (parasitic infection) occurs gradually, it will be understood, that under certain circumstances the healing process may be complete at the seat of injury, while the parasitic development advances further and further within the organism. These periods of latescence and recrudescence excite the question, are not many other infectious suppurative processes in the interior of the organism in like manner due to parasitic develop- ment 2 246 T H. H. C. T II INTI C. [MAY 25, 1872. In cerebro-spinal meningitis the author was not able to demonstrate any parasites, but he was able to do it readily in a case of multiple osteo-myelitis. From this fact he draws the conclusion that there are numerous internal inflammations which belong to the same form of mycosis as the septic processes after wounds. The question whether these parasite developments are not mere accidental and non-essential occurrences in inflammations and suppurations can now scarcely be considered; experiment has demonstrated that parasites induce suppuration and continued fever. Drs. Zahn and Tiègel report as follows: By means of a Bunsen's air pump, according to the method first adopted by Zahn, fluids containing masses of parasites were filtered through cylinders of clay. The clear, faintly sweetish smelling filtrate was injected into rabbits. It excited violent fever which passed over, however, in from one to three days. Repeated injections of four to six grammes of this fluid had always, in the same animals, the same effect. Local suppurations never occurred. On the other hand the fluid containing the parasites killed the animals in a few days even if only one or two grammes were injected beneath the skin. The consequence of this injection was continuous fever, lasting until death and local, often extremely widely extended suppurations. • Influenced with the belief that when the septic mycosis is once implanted in the body, it is only with difficulty overcome, the author thinks that gunshot. wounds should be closed at once; all attempts at removing foreign bodies, the searchiug of the wound, in general, before the occurrence of suppuration should be avoided. Lastly, the author finishes with a historical sketch. Wahl and Recklinghausen first demonstrated the mycotic gastric ulcer. Traube showed the origin of catarrh of the bladder from importation of the parasite germs by the catheter. Klebs demonstrated that this affection may be induced also without the catheter and that this process may pass from the bladder into the ureters and tubuli uriniferi where pyelo-nephritis may be excited. Kohl and Waldeyer reported cases of parasitic, furuncular, intestinal affection in which bacteria penetrated into the blood and lymph vessels. Rindfleisch has demonstrated in pyaemia vibriones in the heart. Recklinghausen and Waldeyer have recog- mised the capillary emboli of pyaemia, typhus, etc., to be colonies of bacterians. Finally mention is made of the workson caries of the teeth by Leber and Rottenstein and on the parasites of diphtheria by Hueter, Tomasi, Letzerich and Oertel. * —-º-º-ºm- SMALL-Pox IN BERLIN.—Variola still prevails to considerable extent in Berlin. The city authorities have alreday expended upon this disease $98,000 since October 1, and a new sum of $20,000 has just been called Out. FEMALE CITY PHYSICIAN.—Miss S. J. Williams has been chosen city physician of Springfield. A G A D E M y o F ME D1 or N E. JAS. GRAHAM, M. D., PREST.; L. WOLF, M.D., SECT. Transactions May 20, 1872. Reported by Joseph Ransohoff. * amºsºmºsºmsº Uterine Fibroid. - DR. N. P. DANDRIDGE presented a specimen with remarks of which we can only give an abstract. The specimen was a tumor removed from the abdominal cavity by Dr. Kearney. Weight 17 ſhs. 9ozs., cicum- ference 28 inches. The external surface was smooth, being covered by peritoneum. An opening is observed on the lower surface of the tumor, leading into what represents the cavity of the uterus. On the right side, the broad ligament, ovary and Fallopian tube were attached to the tumor. On the left side this was true only of a part of the tube and broad ligament. Upon section the mass was found to be occupied internally by a growth of fine and fibrous feel. This mass was of a white color, and of a fibroid nature, the fibres taking an irregular wavy course. Surrounding this mass on every side was the proper uterine tissue, which at the upper part of the tumor was not more than the one- eighth of an inch in thickness. The cavity above men- tioned stretched out about five inches on each side, showing an exaggerated model of cornua of the uterus. The vertical depth did not exceed one inch. Autopsy. This was made eighteen hours after death, and six days after the operation. The stomach was ad- herent to the abdominal wall and was opened inadvert- ently. The adhesions were recent, and readily broken. The peritoneum showed everywhere the results of a re- cent inflammatory action, and the intestinal surfaces especially were covered with recentlymph. The pelvic cavity contained some purulent fluid. Four ligatures and a clamp, which had been used for the arrest of hemorrhage, were found in situ, and the portion of the uterus external to the clamp wore a gangrenous aspect. The portion of the uterus which was not removed by the operation measured three inches in length; about one- third of the corpus uteri remaining. The ovarian veins were distended and filled with clots. DR. KEARNEY, who had performed the operation, very candidly confessed the error in diagnosis which had been made in this instance. The operation was determined upon for the removal of what was supposed to be an ovarian tumor. Hemorrhage was prevented by the use of four sutures, and the stump was retained in the lips of the abdominal wound by a clamp. The history of this case simulated that of an ovarian tumor, and in these cases every man is liable to be deceived. The tumor was first observed about three years ago, and then in the right ovarian region. The great elasticity of the MAY 25, 1872.] TIH. H. C.I.INI c. 247, tumor was mistaken for fluctuation. The cervix and os uteri were fixed in their normal position, and the uterine cavity when examined by the sound, seemed to be of normal length. In this case the great size of the tumor precluded the use of those manipulations by which the mobility of the cervix might otherwise have been determined. - DR. M. B. WRIGHT stated that in this individual case the growth of the tumor resembled that of an ovarian cyst, and the regular menstruation of the patient, seemed to sustain the diagnosis that was made. Again pressure upon the tumor would produce only a very slight de- scent of the cervix, while the cavity of the neck and body were of the normal length. He concluded by re- marking that in his opinion a positive and infallible diagnosis was an impossibility. - DR. DAWSON remarked that the rule by which most surgeons are regulated, is that all solid abdominal tumors should be excluded from operations, and that the reason of this rule is that these tumors are generally uterine and of a fibroid nature. It is very rare to find an ovary subject to fibroid degeneration, while they are on the contrary subject to malignant disease. In many cases of this nature, the depth of the uterine cavity, on account of the location of the tumor, was liable to mis- lead the most skillful diagnostician, but he doubted whether the elasticity of fibroid tumors could be mistaken for fluctuation. To the rule that ovarian tumors first make their appearance on one side, there are some exceptions, and Bright reports a number of these. It is also generally supposed that when the uterine cavity is greatly lengthened, the tumor is likely to be connected with the womb. This supposition is not to be relied upon, since the uterus and its cavity may be greatly enlarged, and the tumor be ovarian. In the differential diagnosis between ovarian and fibroid tumors, Spencer Wells places great reliance in the complexion of the patient as a diagnostic symptom. He says that the ovarian patient has a pale and sallow hue, while the fibroid tumor is represented by a very florid condition. Dr. Kearney was precluded from the use of this symptom since his patient was of African descent. The speaker then re- ferred to the treatment to be pursued in these cases. If after an error in diagnosis, one of these fibroid tumors be encountered, he considered it advisable to abandon the operation, to close the abdomen and so to give the patient a better chance for recovery, because the re- moval of the uterus through the abdominal walls must necessarily be considered a very unsurgical practice. The Dr. referred to a case upon which he had operated several years ago. The tumor a fluctuating, sub-peri- toneal one, and of a fibro-cystic nature. It was attached to the uterus by a pedicle one and a half inches in length. The tumor was always in the median line, and the uterus was of its proper size and in its normal posi- tion. The tumor was removed without interfering with the uterus. The patient however died. The speaker concluded by remarking that ovarian tumors of very large size could necessarily be felt in the vagina, while uterine tumors may or may not be there distinguished. DR. REAMY stated that the operation for ovarian tumors was certainly justifiable, since Spencer Wells has met with great success, seventy per cent. of his patients recovering. This surgeon places great reliance upon the mobility of the uterus as a diagnostic symptom. A positive diagnosis in these cases is always exceedingly desirable as fibroid tumors always cease growing after attaining a certain size. He then referred to his only fatal case, in which the tumor weighed 52 pounds. This patient died upon the thirty-ninth day after the operation. DR. YoUNG had examined Dr. Kearney's patient, with regard to the mobility of the uterus, and observed only a slight descent of that viscus, when a great pressure was made upon the tumor. No lateral motion was noticed. He did not think that an ovarian tumor must necessarily be felt when a vaginal examination is made. DR CARSON called attention to the case of Dr. Thomas of New York in which the tumor was first observed in the left ovarian region, and hence was supposed to be connected with that ovary. The operation disclosed the fact, that it was connected with the right and not with the left ovary. • DR. N. P. DANDRIDGE observed that his faith in the mobility of the uterus as a diagnostic symptom was considerably shaken by an ovarian cyst which he found in the left ovary. The tumor was about the size of a fist and was firmly adherent to the uterus. It com- pletely surrounded the side and fundus of this organ and the latter would necessarily have been moved by any motion of the tumor. Syphilis. DR. REAMY read a report of a case of specific brain disease which had been very successfully treated by large doses of the iodide of potassium. DR. ILLOWY reported a similar case. The patient has been treated for two years for rheumatism by various physicians. At the first visit, he was unable to walk, and there was a complete paralysis of the muscles of the left arm. The patient had a venereal sore eleven years ago, but had no symptoms of secondary syphilis at that time. He complained of very severe pain at night, and thereupon the diagnosis of tertiary syphilis was based. He was put upon iodide of potassium and iodide of iron, and made a very rapid recovery, the proof of which was his presence at the academy. The paralysis had entirely disappeared, and locomotion is perfect. Cerebro-Spinal Meningitis DR. G. B. ORR reported a case of cerebro-spinal men- ingitis. The patient was a little girl aet. 11 years. She complained of severe headache, and was vomiting pro- fusely. Upon first visit there was no tenderness along the spine and the pupils responded readily to light. The child being constipated, ordered calomel and sub 248 [MAY 25, 1872. TIH. H. cir, TTSTI c. nitrate of bismuth. Upon the following day, the symp- toms were aggravated: marked tenderness along the spine, and decided opisthotonos. Prescribed bromide of potassium, and mustard to the feet; also warm applica- tions to spine. No improvement is manifested under this treatment, and the results are unknown. DR. MALEY also reported a case of this disease, the patient being almost three years old. All the symptoms of the disease was present. Ordered quinia sulph. and a supporting treatment, under which the child rapidly improved. s DR. GRAHAM stated that the case of pleuritic effusion which he reported at the last meeting and in which he had intended to employ paracentesis was not operated upon. Since the last meeting of the Academy four-fifths of the effusion had been absorbed, a rssult which does not warrant an operation. This absorption was going on while the patient was under the influence of large doses of potas, bi-tart, - - Stone. DR, BUCKNER presented a stone whlch was removed from the descending colon of a horse by Dr. Bowl.ER, a veterinary surgeon of the city. The stone weighed 11 ft), 3oz. The horse from which it was removed was twelve years old and had suffered from frequent attacks of colic in" one of which he died. A renal calculus removed from a horse was also presented. —º-º-º- SCIENTIFIC NOTES. Ilostorfer's Syphilitic Blood-cells : Professors well and stricker; War in Scientific Circles. From the Med. Times and Gazette, Apr. 27, ”72. Dr. Lostorfer's corpuscles seen to have become a standing article in the Medical Society of this town, having caused the formation of two parties violently opposed to each other. At the head of the one Professor Stricker has been placed, against his own inclination ; whilst Professor Wedl has voluntarily undertaken the lead of the other. It will be remembered that in a recent meeting of the Medical Society Dr. Lostorfer came forward with the discovery of corpuscles peculiar to the blood of syphilitic patients, by means of which the diagnosis of syphilis may be made by the microscope. This discovery, if true, would have been of the utmost importance, giving a positive basis to the much-discussed question of the relation of microscopic growths to con- tagious and infectious diseases. Everybody was struck with the novelty of the discovery; and it cannot be said that those who have worked in the same direction as Lostorfer did have listened to Lostorfer's lecture without feelings of jealousy. The first who stepped forward to oppose the new theory was Professor Wedl, whose work on pathology has been published by the New Sydenham Society. We are, however, sorry to say that this renowned worker came forward too hastily—neither sufficiently furnished with facts to oppose Lostorfer, nor even acquainted with Lostorfer's investigation; nay, he had not even seen the corpusclesin question, but heard them described by two of his disciples. Standing on such loose ground, he nevertheless denounced Lostorfer's corpuscles to be nothing but fat-cells, which are squeezed out from the skin. When the blood is drawn for micro- Scopic investigation. He further urged that these cor- puscles may be seen a few hours after the preparation is made, and particularly when water is added to the blood. To this Professor Stricker simply replied very clearly, that if a man of Professor Wedl’s renown assures us he has seen fat-cells, there can be no doubt that it was so; but in the present instance it evidences simply that Professor Wedl has seen fat-cells, and not Lostorfer's corpuscles. Dr. Lostorfer has expressly stated—and we have communicated in this journal—that the corpuscles only after the fourth day assume such a size as to be- come visible under the microscope; that they disappear at once if water is added to the blood—so that an object is at once rendered useless if by some chance or accident water had been admixed with it. If, therefore, Profes- sor Wedl had done all which Lostorfer has strongly ad- vised to avoid, he had of course no chance whatever to see the corpuscles in question. At this point the dis- cussion became hot. Dr. Neumann, the well-known dermatologist, supported Professor Wedl; and when Professor Stricker again replied he made use of the ex- pression that one must be a well “rubbed up” micro- scopist (ein geriebener Microscopiker) in order to repeat Dr. Lostorfer's investigations. From this moment the signal was given for guerre à outrance, and, what is more peculiar, from this moment Dr. Lostorfer, the original investigator, was put aside, and Professor Stricker made responsible for theinvestigation of the former—thus, as I said, involuntarily placed at the head of one of the oppos- ing parties. This was the first evening of the great battles. Skirmishing, however, has been going on con- tinually in all the Vienna medical journals; and at every meeting of the Medical Society a paper-war was kept up, Professor Wedl complaining, by letters sent to the Society, of Dr. Auspitz, the secretary, having been biassed by party feelings in framing the report of the discussion, and also accusing Professor Stricker, the editor of the Society's journal, of likewise being partial in performing his duty. To those accusations Professor Stricker and Dr. Auspitz have responded, eliciting again written replies from Professor Wedl, each new letter being more excited, more deviating from the original question, and becoming more personal, and even offensive. Under such circumstances it is evident that the Society's meetings are not always of a very agreeable character. But the war has already produced some good—namely, whether Dr. Lostorfer's teachings be MAY 25, 1872.] TIEEE TEE C T I I INTI C. 249 true or not, they have induced the microscopists to again pay attention to the investigations of blood, which have been neglected in the last two or three decenniads. One of the best experienced blood-investigators, Professsor Stricker is already at work, which he has been forced to assume. From what we have heard of his recent investigations, one thing seems certain—namely, that something has been discovered by Dr. Lostorfer which has not been known in blood. The corpuscles according to Professor Stricker, exist decidedly; they are of a round shape, grow evidently, but form no. projections (as described by Dr. Lostorfer) giving to the observer the impression of projections if a smaller cor- puscle is adjacent to a larger one. Whether or not the corpuscles are peculiar to syphilitic blood Stricker has not yet made out. If I am well informed, we may expect the publication of Professor Stricker's researches in a short time. Whilst in the one camp preparations are thus made for a new battle, Professor Wedl’s army is likewise busy to meet the enemy's movement, or, if necessary, to open the hostilities. Dr. Neumann, we hear, has likewise been engaged in the solution of the important question, and the result of his researches, 1 hear, we shall read in one of the next impressions of the Wiener Wochenschrift. In conclusion, it may be men- tioned that whilst the minds of Medical men are heated by Dr. Lostofer's discovery, Dr. Salisbury is preparing a paper for Dr. Hallier's Journal of Parasitology, in order to claim the right of priority of Dr. Lostorfer's discovery. - THE MOVEMENTS OF THE MEMBRANA TYMPANI.- Dr. Emil Berthold gives an account of the very ingen- ious and beautiful experiments instituted by himself to illustrate the movements in the membrana tympani by sounds conveyed to the ear through the bones of the head. He makes use of a T shaped tube from 4 to 6 inches long, the vertical part.being hermetically fixed in the external meatus, a gas jet in one arm of the hori- zontal part, and the movements being cast upon a revolv- ing mirror at the end of the other horizontal part. The movements are excited by placing a vibrating tuning fork on the bones of the head, or on the teeth, or by the voice. Of course the movements are very slight, so a revolv- ing mirror is necessary to bring them out plainly. It is well known that the eye does not possess the power of separating very rapid movements, inasmuch as the retina retains impressions a certain length of time. Every one is familiar with the ordinary illustration of twirling a stick with a bright coal on the end, if twirled fast it makes a continuous circle of fire, the impression at starting remaining on the retina until the bright point has completed the circle. The author's arrangement, a four sided prism, covered by a plain metallic mirror made to revolve, would cast the image, like other rotating mirrors, upon different parts of the retina. Taking the image of the flame as a horizontal line, while the membrane was at rest, the different tones coming through the cranial bones gave waving lines, differing according to the height or depth of the tone. The deep tones produced waves whose elevations and depressions were further separated from each other than the higher ones; the height of the elevations and the depth of the depressions were less in the deep tones than in the higher. - The difficulty of locating troubles in the middle ear is well known, and the author hopes to be able to re- remove some of this by his investigations, the practical part of which is reserved for a future occasion.—Monats. f. Ohrenheilkunde, March, '72. VIVISECTIONS.—M. Claude Bernard, one of the great- est of living physiologists, in his recent work (Leçons de Pathologie earperimentale) points out the immense value of experimental pathological researches, and the neces- sity for the construction of special physiological labora- tories (like those of Kühne at Amsterdam, and Ludwig at Leipzig) wherever physiology is taught, in order that theory and practice may go hand in hand. Referring to the absurd scruples of the antivivisectionists, he points out the necessity that exists for the daily slaughter of a large number of the lower animals, and gives the follow- ing anecdote in a note: “In one of his campaigns the Duke of Burgundy, son of the Grand Dauphin, wrote to Fénélon to ask whether he might encamp his army under the walls of a nunnery, as, however objectionable in point of morality, the position was peculiarly advan- tageous for the prosecution of the war. Fénélon promptly replied, “Burn the nunnery, but gain the battle.' Now, Fénélon was certainly not a man of lax morals, nor a man of anti-christian spirit, nor a violent character; but he recognised that war has its necessities, which must be obeyed if success is to be ob- obtained. Physiology, too, has its necessities, and these must be submitted to, or all progress must be renounced. —Lancet, March 30, 1872. —-º-º-º- M IELDHCJAL NEWS. THE OPPORTUNITY OF MENSTRUATION.—The mental vagaries, curious conceits and unnatural ideas and de- sires then developed [during menstruation | are as diverse as the pains and aches which, at such times, are so commonly complained of by different patients. It will frequently happen that the peculiar tendency of the individual will then be developed, and an opportunity is thus afforded of learning more of the mental charac- teristics of a woman by a careful observation of her re- marks and attention to her conduct during this period than at any other time.— Vance—Bost. Med. Journ. May 9, '72. RELIEF FOR BAKER BROWN.—The Brit. Med. Journ- mal publishes a weekly list of the donors with their contributions for the reliefof Mr Isaac Baker Brown, who is paralysed and in great pecuniary distress. 250 [MAY 25, 1872. TETH CE,TISTI c. HOMOEOPATHICSURGERY.—The Alta of the 18th inst., announces that “the Homoeopathic system of medicine is to be hereafter represented in the columns of the Pacific Journal of Health, to commence with the May number. The object is to give to the public, popular instruction in its principles, so that they can be easily comprehended, and to impart a knowledge of the science, free from technical terms and dry disquisitions. We understand that the first number in May will contain a well illustrated case of the successful removal of nearly five feet of intestines from a lady in Chicago, by Homoeo- pathic Surgery.” It is thought to be a parody on that literary and, so- called professional monstrosity, Hall's Journal of Health. —Western Lancet, April, '72. FISTULA FOR CYSTITIS.—Our readers will remember the spirited controversy upon this subject in the first volume of our journal. The following letter therefore clipped from the American Practitioner May, '72 is of interest. º BIRMINGHAM, February 18, 1872. DEAR SIR—The first case of which I have cognizance of the operation having been done by Sir James Simpson occurred, I think, in 1860. I have un- fortunately no record of it. I feel certain that he had done the operation before, for he had on several occasions spoken of the operation, yet forgot the case I refer to till I reminded him of it. It is more than likely therefore that it was not his first. Dr. Keith, the celebrated ovariotomist, has told me that the late Mr. Syme had practiced the operation on a male successfully. There can be no doubt that it is a valuable and thoroughly established proceeding, based on Sound surgical princi- ple. The criticisms in THE CLINIC are ill-digested speculations of mere theorists. Yours truly, LAwSON TAIT. PREVENTIVE MEDICINE.—The great instruments of Preventive Medicine will be science, legislative wisdom, and charity—that blessed and fragrant flower of the following of Christ. War, that assimilates man to the brutes, will become more odious as its collateral effects will be better understood. In the war of liberation in Spain, we have the authority of Sir Gilbert Blane in stating that more of our soldiers died of fever than of all other causes, including the sword. A time may come when the conqueror of disease will be more honored than the victor in a hundred fights. The time may come when no man for his own ends, or for his profit, will be permitted to damage the health or the well-being of his neighbor or of his servant, nor the prisoner have to suffer through the ignorance or the in- difference of his jailer a greater penalty than was awarded by the law, while the emigrant with his loved ones will be protected from disease as he expatriates himself from the land of his birth. The gifts to man from Heaven— pure air, pure water, bright light, and wholesome food, will be more freely shared in, and the moral and physical evils of overcrowding, and the consequent guilt, and shame, the pestilence, will disappear. The artisan will be taught the dangers of his particular calling, and so far as law and public opinion go, be protected from them; whether he labor in a hot room, amid the roar of machinery, or deep in the earth where he has to work in passages carved by himself of little more than two feet in hight, inhaling the smoke of gunpowder and particles of silex till his working life comes to an un- timely and miserable end. That false morality which would ignore the existence of, and therefore would neglect, that unhappy class of the victims of Society, will be denounced and exposed. Infant life, concerning the preservation of which civilized England may well take her lesson from Russia, will be protected by the State. The power of science will be brought home to all men, as to everything that can influence health, food, drink, labor, residence, occupation; as it touches each of these considerations, will lead mankind to higher thoughts and purer lives. - The principles of the science of public health will be taught in our Universities, and from them downwards in our elementary schools; and the influence and the light of science be brought to bear upon all men. Think of the millions of our fellow-men—brethren, subjects of the same crown, at home or on the burning plains of India, contending miserably with, or yielding to, the multiplied evils of degradation, and consequent untimely death, from which the ignorance of their rulers as well as of themselves keeps the light of knowledge; and you will admit that it is a noble object for those who dwell in, and who govern, the homes of science— . our ancient teaching Universities of these countries, to prepare and to send out over the world their disciplined and devoted Soldiers of science and of ethics, with the highest academical, and therefore social, rank, to con- tend with and abate those mental and physical evils the growth of ages the offspring of ignorance, which so long have afflicted and retarded mankind.—Stokes— Brit. Med. Journ., Apr. 13, '72. —-º-o-º- I REVIEWS. THE TREATMENT OF VENEREAL DISEASES. A mon- ograph of the method pursued in the Vienna Hospital, etc.—By M. H. Henry, M. D. New York, Wm. Wood & Co., 1872. In this reprint of an article that appeared in the Amer. Jour. of Syphil. and Dermat., April, 1872, the author has presented to the profession 198 prescriptions used in the treatment of venereal diseases in the Vienna Hospital, together with eleven pages of general remarks on the hygiene, dressings, and local treatment of venereal patients in hospital and private practice, and three pages upon prophylaxis, dietetics, and health resorts. We cannot say that we are much in favor of “Books of MAY 25, 1872.] T EEIH C T.I. NI c. 251 Prescriptions” under any circumstances, and most cer- tainly are not at all favorably dispbsed towards those that fail to make it apparent for what class of individuals they were prepared, whether for practitioners or the community at large. From the way in which the pre- scriptions are written, and the remarks appended to many of them, we are inclined to believe that the book under review must have been intended for non-profession- als, a sort of “Every man his own Doctor, or the treatment of venereal diseases made easy in one lesson without a master.” Every educated physician would have pre- ferred that the pharmaceutical names of remedial agents should have been employed, and the R, followed by the genitive, or if the writer must use the common names that the useofsuch should have been strictly and uniform ly adhered to. Asit is, we have neither Latin nor English, neither professional nor ordinary namessystematicallyem ployed; e.g., at one time we see Aqua, at another Water, in one formula. Borate of Soda, in another Borax. Again we find “Liquor sesquichloride of Iron; ” why not either Solution of the Sesquichloride of iron, or “Liquor Ferri Sesqui (Per) chloridi.” Following R. No. 30, (a solution of morphia), it is stated, “to be used hypodermically. Producing sleep and relieving pain.” Who that has any business to be using hypodermically a solution of morphia 20 gr. to the 3., does not know that it is intended by such use to induce sleep and re- lieve pain. The amount to be injected is not stated, and the ignorant man for whose information the effects of the hypodermic administration of morphia are speci- fied will be as likely as not to use all of the prescribed solution that he can get into his hypodermic syringe. R. No. 25 is as follows: “Chloral Hydrate, 3ss. Distilled Water, 3iij. Take one-half, and if the desired hypnotic effect is not produced within five minutes, take the remaining portion. Chloral hydrate must have a different effect either in the Vienna Hospital or in New York than it has here if ordinarily the hypnotic effect of 15 grs. is produced within five minutes. But we forbear to continue these criticisms. The general remarks are good. The mono- graph was very well as an article to fill up the pages of a Medical Journal, but in sending it out in its present shape, the author pays a poor compliment to the in- telligence and wants of his fellow-practitioners, and has added little, if anything, to his own reputation. LITHOTOMY AND LITHOTRITY.-By Gurdon Buck, M. D., New York, Wm. Wood & Co., 1872. In this interesting little monograph we have a report Somewhat in detail of 50 cases of calculus operated on by Dr. Buck of N. Y., by lithotomy and lithotrity, to- gether with some general remarks on lithotrity and the circumstances under which the cutting or crushing opera- tion should be preferably selected. The 50 subjects operated on, in consequence of the relapses that took place in several instances, furnish a table of 60 cases treated by lithotrity and 8 by lithotomy, only 3 of the latter not having been previously subjected to the crush- ing operation. Of the 55 cases of lithotrity alone, 8 died, i. e., 14.5 per cent, and of the 8 lithotomies only 1, i. e., 12.5 per cent. For several reasons, however, these figures cannot be taken as exponents of the rela- tive mortality of the two operations. The general remarks, especially those with reference to the kind of cases that should be subjected to the one operation in preference to the other, are worthy of the careful atten- tion of all interested in the treatment of stone, for when- ever Dr. Buck expresses an opinion on a surgical subject it is always based upon careful observation, reflection and thorough acquaintance with the literature of the pro- fession. The typographical execution of the work under review is excellent. - LECTURES ON AURAL CATARRH; or the Commonest Forms of Deafness and their Cure. By Peter Allen, M. D., Fellow of the Royal College of Surgeons, etc., etc.—These lectures are what the author modestly claims, not an exhaustive treatise, but really cover a wide range in the space of 271 pages. They contain the chief facts of certainly the most common causes of deafness, plainly put and will go far towards placing the reader au niveau with the current ideas on this department of aural surgery. - A book of value, especially to students. –º- e -º--— C LINICALL, MI EM [O] RNAIDA. & Int ception.—Novel Treatment.—Success. BY ALFRED W. TALIAFERRO, M. D., (San Rafeal, Cal.) From the Western (San Francisco) Lancet, April, '72. The following case of invagination of the gut, occurring in the State Prison Hospital, is sent because of the novelty of the treatment adopted and the success attend- ing it. On June 8, 1871, in making my usual visit to the prison, I found in hospital, T. S., aet. 24, admitted fourteen hours previously, apparently suffering from a severe cramp colic, and from which he had obtained no relief. Not doubting but that this was a simple case I ordered the usual remedies without making a very careful examination. The next day he was still suffering intensely and vomiting; there had been no action of the bowels, although the most active medicines had been given by the mouth and as enemata; the hypodermic administration of a grain of morphine had given him a few hours of sleep and ease. A careful examination revealed a mechanical obstruction in the bowels which I diagnosed as being at the ilio-caecal valve, the intense pain being confined to that spot, and an examination per anum demonstrated that the rectum and sigmoid flexure of the colon were free. All efforts to remove 252 [MAY 25, 1872, TIEI IEH C T , T N T C. this obstruction proved abortive. During the evening he commenced vomiting large quantities of faecal matter. On the 11th, he was in a state of collapse, and I returned to San Rafael with no hopes of finding him alive at my visit the next morning; therefore I was greatly surprised on my return to find him not only alive, but in a comfortable condition, and with free evacuations from the bowels | This change was due to the treatment adopted by Wm. Lebur, my steward in the hospital. Lebur reported that as everything directed by me, had failed to relieve the patient, and in consequence of his desperate condition, he had ventured on the evening before, the experiment of inflating the intestines with the effervescing draught, in order that the obstruction might be overcome I This was effected by injecting into the rectum a strong solution of bicarbonate of soda, then a strong solution of tartaric acid, and preventing its egress by making rigorous pressure against the sphincter ani. The result of this experiment was the instant removal of the invagination, and free catharsis. The principle of this treatment becomes obvious when we reflect a moment, and I wonder that it has not been in general use. Our chief aim, in this disorder, being to remove obstruction by inflation of the bowels, what method is there more potent than the one used in this instance 7 * * , " - Lebur is a U. S. prisoner from Oregon, and although in that State before he became a prisoner, he is by no means a “regular.” He claims this treatment as origi- nal; and as far as he is concerned, I believe that it did originate with him on this occasion. . On consulting various authorities, I find only in “Wood's Practice of Medicine,” third edition, any account of similar treatment. It is a simple mention of a report made by Dr. Tate, in the Georgia Southern Medical Journal, of a successful case treated in this Iſla Il Ile I’. - INTESTINAL INVAGINATION.—Dr. Herz (Vienna), spoke(Soc. Phys., Mar. 20, '72,) of the occurrence of invag- ination in childhood at different ages and exhibited by statistics in accord with the views of Hansen Smith and Pilz that the first year and most especially the period *Historical note by Editor [Lancet]. In 1726, Dean Swift wrote Gulliver's Voyage to Laputa. The description of Gulliver's visit to the Grand Academy at Lagado is graphic ; among other things, he says: “I was complaining of a small fit of the colic, upon which my conduc- tor led me into a room where a great physician resided, who was famous for curing that disease by contrary operations from the same instru- ments. He had a large pair of bellows, with a long slender nozzle of ivory ; this was conveyed eight inches up the anus, and drawing in the wind, he affirmed that he cquld make the guts as lank as a dried blad- der. But when the disease was more stubborn and violent, he let in the nozzle while the bellows were full of wind which he discharged into the body of the patient, then withdrew the instrument to replenish it clapping his thumb strongly against the orifice of the fundament ; and this being repeated three or four times, the adventitious wind would rush out, bringing the noxious along with it (like water put into a pump), and the patient recovered. I saw him try both experiments upon a dog, but could not discover any effect-from the former. After the latter, the animal was ready to burst, and made so violent a dis- charge as was very offensive to me and my companion. on the 8pot, and we left the doctor endeavoring to recover him by the same operation. The dog died between the 4–6 months furnished the greatest number of cases. The statements of Rilliet, Hansen Smith and Pilz as to the great preponderance of cases in the male sex were also confirmed. From the analysis of 162 cases collected by Pilzit resulted that 56 per cent. were invaginations of the small intestine into the large. The speaker in this connection discusses the therapy of this affection, placing internal medication in the back- ground, stating that it is limited, indeed, to the exhibi- tion of opium in moderate doses while mechanical agencies, the injection of large quantities of water, in- sufflation of air, the use of the sound played the chief role. - The report includes the narration of a case in which the diagnosis was clearly established, laparotomy was performed by Weinlechner, the section being made over the tumor which was found to be three inches long, two broad, and free from adhesions, though four days had elapsed. The intussusception which consisted of the ascending color and coecum together with the vermiform process, and which measured one foot in length was easily withdrawn, but convulsions set in with symptoms of increasing peritonitis and the child died in six hours. This result, however, should not deter us from future operations, as cases of success are recorded, that for | instance of Spencer Wells.-Aerztliches Litteraturblatt, Mar., '72. GALVANIC TREATMENT OF BED-sores AND INDol- ENT ULCERS.–Dr. Wm. A. Hammond recommends for. indolent ulcers and bed-sores, the galvanic treatment as first recommended by Crussel, of St. Petersburgh. He says:—“During the last six years I have employed it to a great extent in the treatment of bed-sores caused by diseases of the spinal cord, and with scarcely a failure; indeed, I may say without any failure, except in two cases where deep sinuses had formed, which could not be reached by the apparatus. A thin silver plate—no thicker than a sheet of paper—is cut to the exact size and shape of the bed-sore; a zinc plate of about the same size is connected with the silver plate by fine silver or copper wire six or eight inches in length. The silver wire is then placed in immediate contact with the bed-sore, and the zinc plate on some part of the skin above, a piece of chamois-skin soaked in vinegar intervening. This must be kept moist, or there is little or no action of the battery. Within a few hours the effect is perceptible, and in a day or two the cure is complete in a majority of cases. In a few instances a longer time is required. I have frequently seen bed- sores three or four inches in diameter, and half an inch deep, heal over in forty-eight hours. Mr. Spencer Wells states that he has often witnessed large ulcers covered with granulations within twenty-four hours, and com- pletely filled up and cicatrization begun in forty-eight hours. During his recent visit to this country I informed him of my experience, and he reiterated his opinion that it was the best of all methods for treating ulcers of indolent character and bed-sores.”—Pacific Med. and Surg, Journ. O' D C R LEs s A.N ID PA. LATA B L E. In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERs & BARTLETT, of Portsmouth, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. . . . - - Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachilic Affections, in Chronic Rheumatism, &c. . . . . * . The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto, they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin's Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. *. Carriage Manufacturer, Nº. 9 amin East sixth Street, ºt. Main & Sycamºre. I MAKE NOTHING BUT AW/APS 7" CZ.Z.S. S. WºO /*A*, Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of LIGHT FAMILY CAFFIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive variety of light elegant designs of different cost and finish. In vehicles especially adapted to PHYSECHANS” {{SE, The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. The superiority of my light gentlemen's buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price Q li tº lication. References S ists furnished on application. Reference ^ - > Ø fº to Dr. W. W. Dawson and ºil the leading wºrs, V. Physicians in the city and fieighborhood. . .N4– 77 º ||||||}|| MM|| ||NF|| 16?' EAST 34TH-ST., NEW YORK, By Special Appointment Electrical Instrument Makers to * the New York State Hospital for Nervous Diseases, ELECTRO-MAGNETIC MACHINES, Portable Galwanic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, 1870, and May 30th, 1871. These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery Fluid. |M|| |||||—|| || PEERMANIENT BATTERIEs, For Hospitals and General Practitioners, IET IIECTIE,OIDIEHS. For Eye, Ear, Larynx, Nose, Uterus, Wagina, Bladder, Ree- tum, Feet, Phrenic and Sympathetic Nerves, Elec- trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. JEXTRA (!TS FROM THE OPINIONS OF THE MOST IEIMINTENT IMEIHIB ERS OF THIJ PROFESSION. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “Nothing CAN EXCEED THE EFFICIENCY AND CONVENIENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” We are authorized by Prof. Hammond to announce em- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- proved and re-modified Instruments made by our Company. MEREDITH CLYMER, M. D., Prof. of Diseases of the Ner- vous System and of the Mind, &c., &c.—“I consider theºr Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prof. of Surgery, St. Louis:—“In neat- ness, compactness and efficacy, they can not be excelled.” ALFRED C. GARRATT, M.D., Boston :-"In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” f Similar Testimonials have been received from JOHN J. CRANE, M.D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A. MURRAY, M. D.; CHAS. E. BLUMENTHAL, M. D.; E. C. SEGUIN, M. D.; ALLEN MAYNARD, M. D., Cleveland, O.; Dr. C. WANNIE, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES KELLY, Florence, O.; Dr. JOHN BECKER, Brighton, Iowa; Dr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes- barre, Pa.; JOHN J. CALDWELL, M. D., Brooklyn, and many other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an Electrical Instrument for medical purposes. CALL OR SEND FOR CIRCULAR AND PRICE LIST. Fºš" ("E-R’s IP_A_TIEHINTT 28, LIMBs \\ Are furnished to Officers and Soldiers on Government account. - &a I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMES A. FOSTEER, 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street, Cincinnati, Ohio, or 172 Jef. ferson Avenue, Detroit, Mich. wº As SAML. P. THOMAS T.A. I. In O R, IDEALER IN English, French and Scotch GOOIDs, 34 West Fourth Street, & M.W.’6” Z.W.W.??" Z. WILSON BRO'S. S HIRT S Made to order of N. Y. M. Muslin and 2300 HEAVY Linen, per dozen - - - $26 00 Wamsutta Muslin and 2100 HEAVY Lin- en, per dozen - - - - - - - - 33.00 Wamsutta Muslin and 1900 Linen, per doz. 30.00 Lonsdale Muslin and 1700 Linen, per doz. 27.00 First three qualities have ALL LINEN Cuffs and Neckbands. At above prices Cuffs are attached. Same quality of our own manufac- ture, ready-made, $3 per dozen less. Perfect satisfaction given or money cheerfully refunded. Also import and Manufacture Men's Furnish- ing Goods. Pike's Opera-House, Fourth Street, Cincinnati; 931 Wabash Avenue, and 88 West Washington Street, Chicago. CAM.A. R.G.O MANUFACTURING COMPANY., MANUFACTURERS AND IMPORTERS OF AND Window Shades, jº 67 WºSz' Aſotºzºz Szºz, CINCINNXT, O, H. H. BRENEMAN, Proprietor, wan Trºp—ACIENTs. School Teachers, Students AND OTHERS, Can find light and healthful employment for the Summer, by engaging in the sale of our valuable and very popular works. One lady teacher just commencing work for us, reports her net profits for last week at FoETY DoILARs—many others doing equally well, Large commissions or liberal salary as preferred. For particulars, address NETTLETON & CO., 161 Elm Street, CINCINNATI, CB10: P. S.—We will make “SPECIAL TERMs” to medical stu- dents, who are “working their own way through college.” BASEM & CARRENTER, Stationers, Printers -AND-a- Blank Book Manufacturers, 136 VINE sº IEEET, &\\\\\\\\\e IE. D. ALBIRO & BRO. IMPORTERS AND MANUFACTUBERS OF FOREIGN and DOMESTIC WOODS In Veneers, Boards and Plank, frºm:-Mº','!-Biliń'ali ºil, The only house in the Western country that saws Spanish and Mexi- can Cedar for Cigar-Box Makers. We import our own wood direct, and can sell at prices to compete with any and everybody. Also saw and keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. Office and Warerooms, 136 and 138 West Second Street, § Veneer Mill, 507, 509, 511, 513 & 515 W. Sixth St., CINCINNATI, JAMES FO [ESTABLISHED, 1836.] } Importers and Manufacturers of Optical and Physical Instruments, Keep constantly on hand first-class English and French Microscopes, First-class Objects and Microscopieal Apparatus of every descrip- tion, Medical Batteries, Thermometers, IHydrometers, Urinometers and Chemical Glass Ware. *. attention given to adapting the best spectacles to all conditions OT Slgnt. We take pleasure in showing the latest novelties from the best Euro- pean and American manufacturers. JAMES FOSTER, Jr. & Co., S. W. cor. 5th & Race Sts., Cincinnati, O. No. 758 BROADw AY, NEw York HAVE been in the habit of applying and recommending the Truss manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to I E. S. WAYNE Suire & Co., F. E. SUIRE. TH". TD. WHOLESALE DRUGGISTS, TML A-IN TJ” E" A C T TJ IF, IIST G- £Hexists AND FHARMAceutists, CINCINNATI, OHIO. : Have constantly on hand a full assortment of s]ex,)&cºexex, XG)3.U.G.S ANYO WXXX0)(C)(N)es, cºeryx)(cAx. Axºp ARAºus, TESTs, MEDICAL, GLASS WARE, &c., &c., And solicits the patronage of the trade and profession- We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, Made in accordance with the U. S. P. and other recognized authori- ties. ETINIHE ANID IRAIRIE CHEMICALS, Of the popular class of preparations known as IE T, TIXII ER, S, We manufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. Bitter Wine of Iron, & An excellent Chalybeate and tonic, Wine of Ison, &c AGENTS FOR BULLOCK & CRENSHAW'S Sugar-coated Pills and Granules. LEWIS A. SAYIRE, M. D. Surgeon, Bellevue Hospital. *. any I have ever examined. From Prof. Willard Parker to S. D. Townsend. M. D., Surgeon to the Massachusetts General Hospital. B EG leave to state for the benefit of all concerned, that I have known Dr. S. N. Marsh the last fifteen years. * * * I am in the constant habit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hermia. He has instruments superior to any I have ever seen, and his treatment is unattended with anv of the risks to the patient that exist in many of the plans suggested and attempted to be carried into execution. I have confidence in Dr. Marsh as a gentleman of houor and integrity, and as such recommend him to the members of the medi- cal profession generally. WILLARD PARKER, M. D. * Professor of Surgery, New York City Dr. S. N. Marsh's Patent Radical Cure Truss and all other kinds of Trusses, Shoulder Braces, Supporters, Elastic stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Cure Truss Offices of S.N. MARSH & CO., No. 2 Wesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. Price Lists of preparations and of Sugar-coated Pills sent by Mail upon application. The long standing and well and widely known repu- OPPOSITE THE HIGH STEEPLE, & Agents for Clement's Patent Artificial Legs, tation of our house we offer as a guarantee for the reliability of our preparation, and the quality of the goods sold by us generally. º - - º : º.* : [º:| --- ; sº §}. º§ Rº §§ - | i § * CINCINNATI. —º- E" A C TU L T Y - J A M E S G R A H A M, M. D., D E AN, Professor of the The ory and LPractice of Medicine arid Clinical Medicine. ROBERTS BARTHOLOW, M. D., W. W. DAWSON, M.D., Professor of Materia Medica and Therapeutics. Professor of Principles and I’ractice of Surgery and Clinical Surgery. W. H. GQBRECEIT, M.D., Professor of Anatomy. T. A. REAMY, M.D., P. S. CONNER, M.D., Professor of Obstetrics and Diseases of Children. P Surgical Anatomy. º ** JOHN L. CLEVELAND, M.D., JAMES T. W HTTAKER, M.D., Demonstrator of Anatomy. Professor of I’hysiology. SAMUEL NICKLY'S, M.D., CHARLES KEARNS, M.D., Professor of Physics and Medical Chemistry Assistant to the Chair of Surgery. Wr. W. SEELY, M. D., Professor of Diseases of tho Hye and HDar, and Secretary of the Faculty **- T. Louis BrowN, M. I.). Proyer tor of A natomy. E. Noble, Jamitor, College Building, Sirth St., bet. Vine and Race. IPUBLISHED EVERY SATUR DAY. T E R MS-$2.00 a Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editof: All Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer, vol. 2. C IN C IN N A TI, —º J U N E 1, 1872. No. 22. JAS. T. VV HITTAKER, M. D. No. 101 West Ninth Street, Cincinnati, TREASURER. W. W. SEELY, M. D., - - - - - - *- No. 118 West Seventh Street, Cincinnati. Printed and Published by THE CLINIC Publishing Company, ** club RATEs. 4 Copies to one address...................................................... $ 7.00 6 6 4. & C 10,00 12 “ “ ------------------..................“............. 18.00 C O N T E N T S. - - -º-º-º- { Page. ÖRRGINAL ARTICLES Reports of CASEs, T1c Doloreux, Tiron AcKNTESIs, by Roberts , Bartholow, M. D...................................................................253 REMPLANTATION of TEETH, by I. P. Meredith, M. D...............263 TRANSI LATE {DN The Cause of Death (From Caspar's Gerichtl. Medicin. Berlin, 1871).256 ACADEMY or MHEnricº NE - Editor. | WT iſ ºWTſº, | COān & Co. -Platitál Hall's Ali làleſs iſ fashill, 92 FOURTH STREET, Opposite Post Office, CLINTCITNTINTATI, C-, gºy" The Oldest Established Hat House on the Street. “ºff Fine Silk Hats, Standard Quality $6,00. ESIGNERSANPº Transactions May 27, ”72. Punctured Fracture of Skull, by Dr. Conner—Gangrene of Gen- itals, by Dr. Young—Procidentia Vesicae, by Dr. Ludlow—Men- ingitis, by Drs. Whittaker, Thornton, Carson–The State So- ciety—Corrections........... - * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * - - - - - - - - - - - - 258-260 Six HENTIFIC NOTES Lostorfer's Syphilis Corpuscles—Salisbury vs. Lostorfer– The De- velopment of Intellect by Electricity—Physiological Action of Tobacco–A Process for Liquefying the Dead—Fallacies of the Senses—High Science—Artificial Generation................. ------ 260-161 M IELDICAL NEWS' The N. Y. Record on the Amer. Med. Association—Prof. Bamberg- er's Introductory—The Cure of the Prince—A Whiskey Formula —From the Good Old Times—The Assoc. of Med. Editors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * ****** CLINHCAE, NIEMORAN HDA Eucalyptus Globulus in Intermittent Fever–Skin Grafts—Injection of Iodine and Alcohol in Bronchocele—A New Means of Com- batting Muscular Contraction.......................----------.* * * * * * * * * * * * 263-204 Our State Medical Society. * -a as wºmen ºn “we ºwn as * * THE CLINIC of to-day continues the exceedingly in- structive series of articles on medical jurispruden, e. The syphilis bubble has bursted in due confirmation of the hopes and vaticinations of all our soothsayers from birth. In the last number of the Alig. Wien. Med. Zeit., however, Prof. Stricker intimates that possibly these corpuscles, whose existence is certainly established, may prove to be the carriers of the poison. TJnder Clinical Memoranda we have a most interest- ing note on the treatment of malarial disease by the new antiperiodic eucalyptus globulus and a very novel sug- gestion in the way of combatting the rigidity of muscles in fractures and dislocations. :O: The Reports of the Indiana State Society came to hand too late for insertion in this number. RAW Sºgº. ºf * * * * TAFT. J. TAFT, Editor Dental Register J. & W. TAFT, TDIEHINTTISTS 117 WEST FOURTH STREET, CINCIN N ATI, O. A Monthly Journal, CONTAINING 48 PAGES, Devoted to the Interests of the Dental Profession, * William Autenrieth, ROBERT CLARKE & Co's. No. 71 WEst sixTER sºrrºris ET, BETWEEN WAINUT AND WINE, CINCINNATI, OHIO, MANUFACTURER OF AND DEALER IN |||}|| || || |||||||| Abdominal Supporters, Trusses, CLUB-F00T SHOES, SPINAL APPARATUS, ETſ Koeps constantly on hand a full variety of Metalic and Rubber syringes, sº tonnach Pumps, Etc. stockINGS For VARIcose. VEINs. pecial attention given to the fitting of Apparatus for Deformities. Bºy" Agent for DR. L. A. BABC00K'S Silver Uterine Supporter, --ALSO- DR. AHL's POROUS FELT SPLINTs, —A1,SO- T) A Y " S S E T, IN T S \ LIST of New MHL iBTH in Mºulis iſ: GREEN'S PATHOLOGY AND MORBID ANATO MY, 8vo. Cloth. $2 50 DUCHENNE’s LOCALIZED ELECTRIZATION. 8vo. $3 co DILLENBERGER ON WOMEN AND CHILDREN’S DIS- EASES. 12mo. $1 75 BENNETT ON PULMonoRY consumpTION. 8vo. $1 $o FIRST HELP IN ACCIDENTS. 12mo. $1 50 BEASLEY'S DRUGGIST RECEIPT BOOK. 8vo. $3 5o ECHEVERRIA ON EPILEPSY. 8vo. Cloth. $5 oc HOWE ON EMERGENCIES. 8vo. $3 oo HAMMOND ON NERVOUS DISEASES. 8vo. $; oo RINDFLEISCH’S PATHOLOGICAL HISTOLOGY. $6 oo WARINGS’ PRACTICAL THERAPEUTICS, and An. Ed. 8vo. Cloth. $5 oc Leather. $6 oo SCUDDER'S SPECIFIC MEDICATION. 12mo. Cloth. TANNER'S HANDBOOK OF OBSTETRICS. 12 mo. WAN BUREN ON DISEASES OF THE RECTUM. Cloth. $1 50 FLINT'S EXAMINATION OF URINE. 12mo. Cloth. $1 oo VOGEL ON DISEASES OF CHILDREN. 8vo. Cloth. $4 5o BEARD AND ROCKWELL’S MEDICAL AND SURGICAL ECECTRICITY. 8vo. Cloth. $4 50 ATTFIELD'S MEDICAL CHEMISTRY. 12mo, Cloth. $2.75 Leather. $3 25 BARTHOLOW’S HYPODERMIC MEDICATION. Cloth. $1 5o - TURNBULL’S DISEASES OF THE EAR. 8vo. Cloth. $5 OC) TILT'S CHANGE OF LIFE. 8vo. Cloth. $5 oc NEUMANN'S HAND-BOOK OF SKIN DISEASES. Cloth. $4 oo ANSTIE ON NEURALGIA. 8vo. Cloth. $3 oo. PANCOAST'S OPERATIVE SURGERY. 4to., with many plates. $1 o oo HOOD ON BONE SETTING. 12mo. $1 5o RINGER'S HAND-BOOK OF THERAPEUTICS. 8vo. $4 oo $2 5o $2 oo . A 2.1]). O, | 2, ITIOs 8vo. Hoºs PARTURITION WITHOUT PA I N. 16mo. I OO PROCTER'S LIGHT SCIENCE FOR LEISURE HOURS. 12mo. $1 75 BERNARD's PHYSIOLOGY OF THE HEART, 50 cts. BARNES’ OBSTETRICAL OPERATIONS. 8vo. $4 5o NICHOL’S FIRESIDE SCIENCE. 12mo, $1 50. WOHLER'S MINERAL ANALYSIS. 12mo. Cloth. $3 oo PLATTNER'S MANUAL OF ANALYSIS WITH THE BLOWPIPE. 8vo. Cloth. $7 5o JEFFRIES ON THE EYE. 8vo. Cloth. $1 oo MANSFIELD, A THEORY OF SALTS. 8vo. Cloth. $4 oo JEFFRIES ON THE SKIN. 8vo. Cloth. $1 oo GARDENING FOR PROFIT. 12mo. Cloth. $1 5o PRACTICAL FLORICULTURE. 12mo. Cloth. $1 5o FULLER'S SMALL FRUIT CULTURE. 12mo. Cloth. $1 WOODWARD'S COUNTRY HOMES. 12mo, Cloth. $1 DARWIN'S ORIGIN OF SPECIES. 12mo. Cloth. $2. ARTHUR'S TREATMENT AND PREVENTION OF D CAY OF THE TEETH. 12mo. $1 5o TYND ALL ON LIGHT AND ELECTRICITY. THE AMATEUR, MICROSCOPIST. Small 4to. BOOKS IN PREPARATION. BRYANT'S PRACTICE OF SURGERY. BARNES ON DISEASES OF WOMTEN. ROBERTS ON RENAL DISEASES. GUERSANT, SURGICAL DISEASES OF WOMEN AND CHILDREN. Medical, Scientific, and other Catologues sent on application. Any book in the above list sent by mail or express, free of charge on receipt of price. 5o 5o OC) E- 12mo.81 25 $1 75 S. W. Elliott’s Saddle-bags 65 West 4th Street, Cincinnati, Ohio. -r List of Pharmaceutical Preparations, - MANUFACTURED BY Jonºv wrazºº anorarn, FITILADELPHIA. —º- -u- ELIX. PHOS. IRON, QUININE AND STRYCHNIA, ELIXIR OF GENTIAN FERRATED, ELIXIR WALERIANATE OF AMMONIA, (Goddard’s Formula,) - - - ELIXIRVALERIANATEAMMONIA AND QUININE, ELIXIR OF THE FYROPHOSFHATE OF IRON, FERRATED ELIXIR OF CINCHONA, - ELIXIR OF CALISAYA BARK, Iron, Peruvian Bark and choice Aromatics, ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND syRUP OF HYPOPHOSPHITES, ‘. - "compound syrup of PHosphaTES, OR CHEMICAL FOOD, Composed of the Phospinates of Lime, Soda, Potassa and Hron, BITTER WINE OF IRON, Citrate of Iron and Peruvian Bark, . . . . FERRATED CORDIAL ELIXIR, ELIXIR CALISAYA BARK, WINE AND BISMUTH, - ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, - - FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, - TASTELESS COD LIVER OIL, TASTELESS COD LIVER OIL. FERRATED, . . . . BEEF, IRON AND WINE, Extraet of Beef, Citrate of Iron and sherry wine, ELIXIRVALERIANATE OF STRYCHNIA, WINE OF PEPSIN SYRUPSUPERPHOSPHATE OF IRON, J sº - ELIXIR OF BISMUTH, COMP. FLUIDEXT. BUCHU AND PAREIRA BRAVA. - - suſpIPO's ITOERIEs. Bectum, Waginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great eare, and of every variety of combination. Lists sent on application. SPONGE TEN TS.—For the Urethra, of every size and style, made of finest quality of sponge. ---as- -- * - * º: º:ºrº. - - Ezº. Prº-º-º-º: *...* , = , = º: ãº.º- c Hillſ; riſiſ, #E=##### i # § i. º | | iſ | ~-º-º-º-º-º-º: |}|| | ||.. Şā. # § _j i. §: i ºf *- #|#######| || # º ºilº. ºff #3; º | º , tº ...ºiri, #. i. * § |. #" ſ .# - * twº §§ : Hºº #fff; º º § * º º ſº ill; 3. s º: º º §§ º: º ###### | º: ºil º: - º: º ###### # º §§º Żºlº º º Sºs †- tº : # * , f : ...lºº º º º º § º §§ †-º º º, º º # | ; ſº - {{#ſ - f l º; ; ; w - º §: º, º ºs * I I, ſ | |ſº : º, àº; y § ſº % % º Ž. º 2/3 º % º ſº V. ğ% - --- Zº-ºº ºf º 'º º -] º º:#######2, fºſtº, ſº º - * A-º-º-º-º ºw ºf . § - sº 3:#: ºº ſº §§% §§2:... ??. § %3 §§§32 ſº %22%2/3% 2 šāºšºftº -º-º-º->~~~s ºr * º ===#ºś% #% -s- % * ºccº-s: --- E== ===sº Nº Sº ºf * - §:==== --—— (!_LINICAL MHEMIORNADA. Eucalyptus Globulus in Intermittent Fever. From the Brit. Med. Journ., May 11, ’72. About two years ago, Dr. Lorinser of Vienna laid before the profession the results of his observations on the treatment of ague by the Eucalyptus Globulus. A supply of the tincture was placed, for the purpose of ob- servation, at the disposal of medical men connected with the railway stations in localities where ague was frequent. The quantity, however, was but small ; and a larger supply was distributed in May of last year. The results obtained during the summer have been collected and analysed by . Dr. Joseph Keller, chief physician of the Austrian railway company. ge - The number of patients treated with tincture of eucalyptus was 432. Of these, 310 (71.76 per cent.) were perfectly cured; and 122 (28.24) required to be afterwards treated with quinine. Of the 310 patients who were cured, no paroxysm occurred after the first TIEEE THE C T , T INT I C . 263 dose in 202; in the remaining 108, there were one or more subsequent paroxysms, which, however, yielded to repeated doses of the medicine. Quinine had been given without result in 118 of the 432 cases; 293 of the patients had had ague in previous years, and 139 were attacked for the first time in 1871. Of the 122 cases in which the eucalyptus failed, 58 recovered under the use of quinine, 38 were not cured, 10 were sent home, and 16 remained under treatment. Of the 118 cases in which quinine had been given unsuccessfully, 91 recovered under the use of eucalyptus, and in 27 no result followed. The several types of intermittent fever were represent- ed as follows: quotidian, complicated, 117, simple 73=190; tertian complicated 126, simple 95=221; quartan, complicated 16, simple 4=20; quintan, com- plicated, 1. The complications were, enlargement of the spleen or liver, anaemia or chronic gastric catarrh, paludal cachexia, etc. The remedy was successful in 161 of the 260 complicated cases, or 61.9 per cent, ; and in 149 [or 86.6 per cent.] of the 172 simple cases. The percentages of success in the several types were: in tertian, 75.57; in quartan, 70, in quotidian, 67.89. Among the cases in which the first dose of eucalyptus arrested the disease, were 95 complicated and 107 sim- ple; 28 of the former and 20 of the latter had previously been treated unsuccessfully with quinine. In the cases where the paroxysms recurred, there were 70 compli- cated and 38 simple; quinine had been given without success in 27 of the former and in 15 of the latter. Of the 432 patients, 353 were men, 46 women, and 33 children. There were 155 patients who were immigrants into the localities; and in these the disease was more frequently attended with complications, and the treat- ment was less successful than among the indigenous in- habitants. The treatment was generally commenced on the fifth day after the first paroxysm of ague; its duration averaged 93 days, that with quinine in previous years having been 123 days. The tincture was made by dividing into small pieces the leaves of eucalyptus obtained through France from the native country of the plant, and macerating in alcohol for three months. Ten pounds of the leaves yielded twenty-five quarts of the tincture. The average dose was two drachms; and the average quantity used for each patient was seven drachms—this, however, varied much, according to the nature of the case and its complications. Dr. Keller concludes that eucalyptus must be re- garded as a very important remedy for ague; but that the plant as cultivated in Austria is less efficacious than that imported from its native soil; that the remedy is of service especially in obstinate cases of ague where quinine has been given unsuccessfully; and that the average duration of treatment by eucalyptus is shorter than that by quinine. He believes that the tincture is the most eligible preparation of the plant, as the essential oil is retained. The cost of a quart of the 264 [JUNE 1, 1872. TIH. H. C.I.I.INI c. tincture he calculates to be less than two florins ($1). It has a pleasant aromatic flavor. For women and children some simple or orange syrup may be added. In the milder cases, two or three teaspoonsful, taken before the expected paroxysm, are generally sufficient. Where cachexia is present, small doses should be taken night and morning for some time. SKIN-GRAFTs.—M. Olliver of Lyons considers that the connective tissue and not the epidermis is the active agent in the graft, and objects to sowing a number of small epidermic grafts. He cuts them from six to eight centimétres in length, and they succeed very well; but it is inconvenient to procure such large grafts. He freezes the skin before cutting it away, and finds that it still answers well, notwithstanding this assault upon its vitality. This is a veritable autoplasty, and the healed Snrface has a more persistent vitality than ordinary cicatrices. INJECTION OF TINCTURE OF IODINE AND OF ALCO- Hol. IN BRONCHOCELE.—Dr. Karl Schwalbe ( Virchow's Archiv, Band 54) speaks of injection of tincture of iodine and of alcohol in the treatment of thyroid tumors. Those in which it succeeds best are the soft and cystic enlargements; in hard fibrous, tumors no result is ob- tained ; and in vascular swellings there is danger of the production of embolism, unless the vessels have been partially contracted and the tumor diminished by the internal use of iodine and by electrolysis. If blood escape in a stream on the introduction of a cannula, the injection must not be made; in any other case, it may be done with safety. About ten or twenty drops are injected as nearly as possible in the middle line of the neck over the tumor, by means of a syringe fitted with a cannula having a short point. If no blood flow on the introduction of the cannula, the fluid is forced in ; and before removing the instrument, the operator waits for a short time in order that the injection may not again flow out. The operation is sometimes followed by transient pain in the course of the nervus auricularis magnus, cough, gastric oppression, vomiting, and in weak subjects by fainting. One woman, who was sub- ject to epilepsy, was seized with symptoms of hemiplegia soon after the injection, and died in convulsions. Schwalbe prefers alcohol for the injection, a drachm of iodide of potassium being at the same time taken daily. The injection may be repeated at weekly intervals. No confinement is required during the treatment; the average duration of which is two or three months.- Wiener Medizin. Wochenschr., March 16, 1872. A NEW MEANS OF COMBATTING MUSCULAR CON- TRACTION.—Every one is familiar with the resistance offered by muscular contraction in the reduction of dis- locations or of fractures with displacements of the frag- ments. In order to avoid this difficulty resort is had to reduction as soon after the accident as possible to profit by the condition of stupor existent at that time. After this period etherisation becomes necessary. M. Broca, however, has devised a means which is void of the in- conveniences of anaesthesia; it is compression of the principal artery of the wounded limb. The muscles de- prived of the blood necessary for the exercise of their functions by compression of the brachial or femoral arteries are unable to contract. By means of this prac- tice M. Broca has already succeeded on a number of Occasions without recourse to anaesthesia.-Lyon Méd- icale, Apr. 28, '72. - - —-º-º-º- Our State Medical Society [The approaching session of the State Society promises to be one of the largest and most enthusiastic gatherings in the history of the association. A number of most interesting papers will be presented, we learn, and but little time is to be devoted to ethics, and other nonsense. The following letter from the Secretary explains itself:J - CINCINNATI, OHIO, May 23, 1872. The Ohio State Medical Society will hold its Annual Meeting this year at Portsmouth, Ohio, beginning Tuesday, June 11th. Arrangements have been made for reduction of fare, to members and their families with the following Rail- roads: - Marietta & Cincinnati Railroad—Half Fare. Round Trip Tickets good from June 8th to 15th. Secretary will furnish return certificates. Cincinnati, Hamilton & Dayton and Cincinnati, Rich- mond & Chicago Railroads.-Hamilton to Richmond, Half-Fare. Return Tickets good until the 15th. Cincinnati, Sandusky & Cleveland Railroad.—Round Trip Tickets to Dayton and Return at Half Fare. Tickets good going, from June 8th to 11th ; returning, until the 15th. Columbus & Hocking Valley Railroad.—Round Trip Tickets at Half Fare. Good on return, June 13th, 14th and 15th only. - - Baltimore & Ohio Railroad Company.—If twenty-five passengers are guaranteed, will place on sale Round Trip Tickets at principal Stations on Central Ohio and Lake Erie Division, via Columbus, for four cents per mile, one way, to Columbus; the rates of other Roads will then be charged thence to Portsmouth. The following Roads refuse any reduction in fare : Pitsburg, Ft. Wayne & Chicago Railway; Cleveland and Pittsburg and Erie & Pittsburg Railroads; Pittsburg Cincinnati & St. Louis Railway, and leased lines; Grand Rapids and Indiana Railroad, and leased lines. Also, Cleveland, Columbus, Cincinnati & Indianapolis Railway Company. - It will be necessary for Members to show their Circular to Ticket Agents and Conductors. W. W. DAWSON, M. D., PREST. J. W. HADLOCK, M. D. Assistant Secretary Ohio State Medical Society. —º-º-º- . CoRRECTION, Semi-Centennial Catalogue: J. Powers Orr instead of (Powers Orr), Ind., 1865. DIVIDED MEDICINES, The Divided Medicine Com'y, a " & CINCINNATI, OHIO. The Company have the honor of bringing to the notice of the Profession, this NEw AND ExCEEDINGLY PRACTICAL - METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. The Divided Medicines are prepared by FREDERICK KRAUs, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MORE. The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every square will consequently contain accurately measured quantities. But not only SoLUBLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINES. .5% 9 This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, ; : #, sh, Ibo, and even lobo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. * * Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE TO SPOIL BY ANY LENGTH OF TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calls with good accurately dosed medicines; and that these medicines have the superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. For Samples, Price Lists, and Agencies, address The Divided Medicine §§ TBOX 26ss, Or FRFDERICK KRAUS, Chemist and Druggist, walnut Hills, Cincinnati, O. MR. FREDERYCK KRAUs: - CINCINNAT1, February 15, 1871. Dear Sir—The specimens of your “ Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: SULPH:MORPHII....................... % grain in each square. ARSEN: ACID.......................... 1-20 grain in each square. “ CHIN INI .......................] & 4 6 & ſº tº CALOMEL.............................. % { { • 6 4 & * COPPER ........................}, 63 RESPECTFULLY YoUBs, -- . - E. S. WAYNE, Analytic Chemist. Carriage Manufacturer, Nº. 9 and Il Fast Sixth Street, ºt. Main & Sycamore. I MAKE NOTHING BUT runsz, czzss ºroma', Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of LIGHT FAMILY CARRIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very €X- tensive variety of light elegant designs of different cost and finish. In vehicles especially adapted to - - PHYSECHANS” (SE. The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. The superiority of my light gentlemen's buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price lists furnished on application. References to Dr. W. W. Dawson and all the leading Physicians in the city and heighborhood. |||||}|| WMF (MºW 167 EAST 34TH-ST., NEW YORK, By Special Appointment Electrical Instrument Makers to the New York State Hospital for Nervous Diseases, MANUFACTURERs of PortABLE ELECTRO-MAGNETIC MACHINES, Portable Galwamic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, 1870, and May 30th, 1871. These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery Fluid. Mill lllll-llſ. Millſ, For Hospitals and General Practitioners, IETIECTIER, CTDES. For Eye, Ear, Larynx, Nose, Uterus, Wagina, Bladder, Rec- tum, Feet, Phrenic and Sympathetic Nerves, Eleo- trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. IEXTRA (!TS FRONT THE O PINIONS OF THE MOST IEIMINIENT MEMBERS OF THE PROFESS / O N. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “NoTHING cAN EXCEED THE EFFICIENCY AND CONVENIENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” We are authorized by Prof. Hammond to announce en- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- proved and re-modified Instruments made by our Company. MEREDITH CLYMER, M. D., Prof. of Diseases of the Neº- vous System and of the Mind, &c., &c.—“I consider their Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prof. of Surgery, St. Louis:—‘ In meat- ness, compactness and efficacy, they can not be excelled.” ALFRED C. GARRATT, M. D., Boston :-"In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” Similar Testimonials have been received from JOHN J. CRANE, M.D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A. MURRAY, M. D.; CHAS. E. BLUMENTHAL, M. D.; E. C. SEGUIN, M. D.; ALLEN MAYNARD, M. D., Cleveland, O.; Dr. C. WANNIE, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES KELLY, Florence, 0.; Dr. JOHN BECKER, Brighton, Iowa; Dr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes- barre, Pa.; JOHN J. CALDWELL, M. D., Brooklyn, and many other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an Dlectrical Instrument for medical purposes. CALL OR SEND FOR CIRCULAR AND PRICE LIST. IE_A_TIE TSTT –28, LIMBs \\ Are furnished to Officers and Soldiers on Government account. - - I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMEs A. FO's"TEER, 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street, Cincinnnnati, Ohio, or 172 Jef- ferson Avenue, Detroit, Mich. SAML. P. THOMAS T.A. I. I. O R, DEALEF IN English French and Scotch GOODs, 34 West Fourth Street, ("Z.W’("A.W.W.??"/. WILSON BRO's S HIRTS Made to order of N. Y. M. Muslin and 2300 HEAVY Linen, per dozen - - - $26 00 Wamsutta Muslin and 2100 HEAVY Lin- en, per dozen - - - - - - - - 33.00 Wamsutta Muslin and 1900 Linen, per doz. 30.00 Lonsdale Muslin and 1700 Linen, per doz. 27.0) First three qualities have ALL LINEN Cuffs and Neckbands. At above prices Cuffs are attached. Same quality of our own manufac- ture, ready-made, $3 per dozen less. Perfect satisfaction given or money cheerfully refunded. Also import and Manufacture Men’s Furnish- ing Goods. Pike's Opera-House, Fourth Street, Cincinnati; 931 Wabash Avenue, and 88 West Washington Street, Chicago. CAMARGO MANUFACTURING COMPANY., MANUFACTURERS AND IMPORTERS OF Window Shades, 67 WºSz' Aſotºziz Szºz, CINCINNXTI, O, H. H. BRENEMAN, Proprietor, wanTED–Acriºrs. School Teachers, Students AND OTHERS, Can find light and healthful employment for the Summer, by engaging in the sale of our valuable and very popular works. One lady teacher just commencing work for us, reports her net profits for last week at FoETY DoILARs—many others doing equally well. Large commissions or liberal salary as preferred. For particulars, address - NETTLETON & CO., 161 Elm Street, CINCINNATI, 0B10. P. S.—We will make “special, TERMs” to medical stu- dents, who are “working their own way through college.” BASCOM & CARPENTER, -AND- Blank Book Manufacturers, 136 v1.NE sºrrºrDBT, &\\\\\\\\e E. D. ALBRO & BRO. IMPORTERS AND MANUFACTURESRS OF FOREIGN and DOMESTIC WOODS In Veneers, Boards and Plank, frºm:-Maº', 'al-Biliń'anilal-Bitri'Wii, The only house in the Western country that saws Spanish and Mexi- can Cedar for Cigar-Box Makers. We import our own wood direct, and can sell at prices to compete with any and everybody. Also saw and keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. office and warerooms, 136 and 138 West Second Street, Veneer Mill, 507, 509, 511, 513 & 515 W. Sixth St., CINCINNATI, &- É. § § Simiº - : º JAMEs Fosºrºr, [ESTABLISHED, 1836.] Importers and Manufacturers of Optical and Physical Instruments, Keep constantly on hand first-class English and French Microscopes, First-class Objects and Microscopical Apparatus of every descrip- tion, Medfeal Baiteries, Thermometers, Hydrometers, Urinometers and Chemical Glass Ware. sº attention given to adapting the best spectacles to all conditions OI signt. We take pleasure in showing the latest-novelties from the best Euro- pean and American manufacturers. JAMES FosTER, Jr. & Co., - S. W. cor. 5th & Race Sts., Cincinnati, 0. ISR's.N.M.A.R.S.H.’s No. 758 BROADWAY, NEw York I HAVE been in the habit of applying and recommending the Truss' manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- .ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, 1 think it far preferable to any I have ever examined. LEWIS A. SAY RE, M. D. Surgeon, Bellevue Hospital. Parker to S. D. Townsend M. D., Surgeon to the Massachusetts General Hospital, BEG leave to state for the benefit of all concerned, that I have known lor. S. N. Marsh the last fifteen years. * * * I am in the constant habit of sending my patients to him for treatment. I have been delighted From Prof. Willard and his treatment is unattended with anv of the risks to the patient that exist in many of the plans suggested and atteumpted to be carried . into execution. I have confidence in Dr. Marsh as a gentleman of honol and integrity, and as such recommend him to the members of the medi- || WILLARD PAlt KER, MI. D. cal profession generally. * * * - Professor of Surgery, New York City Dr. S. N. Marsh's Patent Radical Cure Truss and all other kinds of Trusses, Shoulder, Braces, . Supporters, Elastic Stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Grub Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Qure Truss Offices of S.N. MARSH & CO., No. 2 Vesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. F. E. SUIRE. F. E. t E. S. WAYNE & Co., wholesale DRuggists, M. A-TN U E A CT Uſ ER, IIST G. £Hemists AND FHARMAceutists, CINCINNATI, OHIO, Have constantly on hand a full assortment of SYSX. EcºEXO O)3 U G. S ANYO IYYXXJXCXN Es, cxxxeryxxcAX, APPARAºcus, TESTS, MEDICAI, GLASS WARE, &c., &c., And solicits the patronage of the trade and profession. We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, Made in accordince with the U. S. P. and other recognized authori- ties. * ETINIHE ANTO EAR HE CHEMICALS. Of the popular class of preparations known as IE T, I DK I F, S, We manufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to º - - * . * * * * * - take. with his Truss, and the success he has met with in producing a Radical || ; , . Cure of Hernia. He has instruments superior to any I have ever seen, | Bitter wine of Iron, * An excellent Chalybeate and tonic, Wine of Ison, &c. AGENTS FOR BULLOCK & CRENSHAW'S $. Sugar-coated Pills and Granules. OPPOSITE THE HIGH STEEPLE, * Agents for Clement's Patent Artificial Legs. . ] f Price Lists of preparations and of Sugar-coated Pills sent by Mail upon application. The long standing and well and widely known repu- zation of our house we offer as a guarantee for the reliability of our preparation, and the quality of the goods sold by us generally. • CINCINNATI. —º- E" A C U E. T. Y - J A M E S G R A H A M, M. D., DE AN, I’rofessor of the Theory and Practice of Medicine and Clinical Medicine. ROBERTS BARTHOLOW, M.D., W. W. DAWSON, M.D., Professor of Materia Medica and Therapeutics. Professor of Principles and Practice of Surgery and Clinical Surgery. W. H. GOBRECHT, M.D., e - Professor of Anatomy. T. A. REAMY, M.D., P. S. CONNER, M. D., Professor of Obstetrics and Diseases of Children. Professor of Surgical Anatomy. JAMES T. WHITTAKER, M. 5, Professor of Physiology. JOHN L. CLEVELAND, M.D., Demonstrator of Anatomy. SAMUEL NICKLYCS, M. D., - CHARLES KEARNS, M.D., Professor of Physics and Medical Chemistry Assistant to the Chair of Surgery. W. VV. S.H.E.I.Y., M. TX., I’ro ſers-on' of IDix earses of the Hye and HJar, and Secretary of the Faculty e-- T. LOU (H Picows, M. I.). Proner for of Anatomy. J. NoPLE, Janitor, College Building, Sirth St., bet. Vine and Race. & PUBLISHED EVERY SATURDAY. - - TERMs—82.00 a Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editor: - All Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer. *------- -* vol. 2. C IN C IN N A TI, J U N E 8, 1872. - No. 23. :::::::::::… *}M T. M. T. MTAſſº, ww.sirty, w. ". . . . . . . tºum. ºn - 2 - - tº-e== * 00án & Co Printed * * tº the cut Pºlis * in 11 º →ºn-faitā Hālā; allºis ºf Him - ** one-dawn º ~ ...s 7.00 - 92 FOURTH STREET, 6 & 4 “ .: .... 10,00 . opposite Post Office, 12 6 & & © . 7 = - 18.0ſ) - CINTCINTINTA TT, C-, c o N T E N T S. lar The ºldest Established Hat House on the Street. *Sa – “Fine Silk Hats, Standard Quality $600. origiNAL ARTICLEs DIABETES Msirirus, by S. D. Nickles, M. D. ~~~~ ......265 r −-º-º-º- º-º-º-º-º-º-º-º: DIGITALIS IN DELIRIUM TREMENs, by J. H. Parker, M. D...............267 @ ogº.Tºrikºſan TRANs|ArroN - , , , |0) ºf § Nº. Galvano-Caustic Tracheotomy by Dr. M. Werneuil, (From the Gaz. - wº 2ESIGNERSA) º sº Med. de Paris, April 27, ”T2)..... 208 - |ENGR AVE R So NWOO Dà * , - —*— " , , º º- - º'ſ §§2 MEST FOURTH: Sº The Influence of the Mind on the Body by Daniel H. Tuke, M. D. (From the Journ. Mental Science, London, Apr., '72.)...........,266 - ACADEMY or MEDICINE — * * * * * *m. Transactions June 3, '72. . . - J T AFT W. TAFT - e *... * * -- © e . Cerebro-Spinal Meningitis, by Dr. C. O. Wright—Discussion by Editor Dental Register Drs. Bartholow, M.B. Wright, Muscroft and Reamy—Aortic Valvular Disease, Specimen by Dr. Buckner—Discussion by Drs. Graham and Carson—Intra-Uterine Medication by Dr. - J - & W TAFT 271 - [...] y Palmer NTE DHCA. L NEWS Indiana State Medical Society, 22nd Annual Session—Paris Troub- les and the Doctors—A New Profession for Ladies—The Stras- - ID E. : S - bourg Festivities—German Therapy * * 273-276 - IN N I I CLINICAL MEMORAN DA Xylol in Small-Pox—Test for Purity of cº-ºwn. & Cº - ºr gº ºn 4 - - - - - 276 * t - HOME NEWS..., * - ~ . 276 117. WEST FOU RTH STRE ET, To Dr. G. O. Woolen, of Indianapolis, Ind., we are - + . indebted for papers containing the very handsome CHIN CININ A TI e O. abstract of the Indiana State Society proceedings. Galvano-Caustic Tracheotomy is at least a novelty if nothing more. - - - The various instances showing the direct influence of the mind on the body are official confirmations of many popular notions. . . . . - - º note on German . will be likely to straighten some erroneous professional ideas just now - - ºr Just A Monthly Journal, . Our Clinical Memoranda to-day contain two most instructive notes, one detailing the exact value of xylol, - CONTAINING 48 PAGES the new remedy for small-pox, the other explaining the y * why certain cases of adenoma are necessarily 3.08.i. - - Devoted to the Interests of the Dental Profession, WILSON BRO's I S HIRT S Made to order of N. Y. M. Muslin and 2300 || $26 00 | HEAVY Linen, per dozen - - - Wamsutta Muslin and 2100 HEAVY Lin- en, per dozen - - - - - - - - 33.00 Wamsutta Muslin and 1900 Linen, per doz. 30.00 Lonsdale Muslin and 1700 Linen, per doz. 27.00 First three qualities have ALL LINEN Cuffs and Neckbands. . At above prices Cuffs are attached. Same quality of our own manufac- ture, ready-made, $3 per dozen less. Perfect satisfaction given or money cheerfully " . . refunded. Also import and Manufacture Men’s Furnish- ing Goods. Pike's opera-House, Fourth street, Cincinnati; 931 Wabash Avenue, and 88 West Washington Street, Chicago. . CAM'ſ A LRG-O MANUFACTURING COMPANY., MANUFACTUREBs AND IMPORTERS OF AND Window Shades, 67 WºSz" Motºzº Szººz', CINCINNXT, O, H. H. BRENEMAN, Proprietor, warran–Acrºrs. School Teachers, Students AND OTHERS, Can find light and healthful employment for the Summer, by engaging in the sale of our valuable and very popular works. One lady teacher just commencing work for us; reports her net profits for last week at FoETY DoILARS-many others doing equally well. Large commissions or liberal salary as preferred. For particulars, address NETTLETON & CO., 161 Elm Street, CINCINNATI, OHIO: P. S.—We will make “SPECIAL TERMs” to medical stu- dents, who are “working their own way through college.” BASCOM & CARPENTER, Stationers, Printers Blank Book Manufacturers, 136 VINE sº DEREET, s\SYNN, ALBRO & BRo. E. D. - IMPORTERs AND MANUFACTURERs or FOREIGN and DOMESTIC WOODS In Veneers, Boards and Plank, Trºis-Mº','l-Birčani ºil-Bütº'º, The only house in the Western country that saws Spanish and Mexi: can Cedar for Cigar-Box Makers. We import our own wood direct, and can sell at prices to compete with any and everybody. - - Also saw and keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. office and warerooms, 136 and 138 West Second street, - Weneer Mill, 507, 509, 511, 513 & 515 W. Sixth St., CINCINNATi, william Autenrieth, * * west sixTH strºr, min un a un . . oncinnar, onio, III III IIIT III.In Abdominal supporter, Trusses, CLUBF00T SHOEs, ; : SPINAL APPARATUS, ETC Keeps constantly on hand a full variety of Metalic and Rubber Syringes, stomach Purmps, Etc., stockings Foa vaſºcose vetNs. special attention given to the fitting of Apparatus for Deformities. sº-Agent for Dr. L. A. BABcock's Silver Uterine Supporter, -º- DR. AHLS. POROUS FELT SPLINTS, - —ALSO– DAY's ser, INTs -AND- S. w. Elliott's | ROBERT CLARKE & CD's. LIST OF NEW 7% MHL iBTH in Mºllāſ; hiſ |GREEN's PATHology AND MORBID ANATOMY, 8vo. - Cloth. $2 5o - - - DUCHENNE'S LOCALIZED ELECTRIZATION. 8vo. $3 oo DILLENBERGER ON WOMEN AND CHILDREN’S DIS- EASES. 12mo. $1 75 - BENNETT ON PULMONORY CONSUMPTION. 8vo. $1 FIRST HELP IN ACCIDENTS. 12mo. $1 50 BEASLEY'S DRUGGIST RECEIPT BOOK. 8vo. $3 50 ECHEVERRIA ON EPILEPSY. 8vo. Cloth. $5 od HOWE ON EMERGENCIES. 8vo. $3 oo HAMMOND ON NERVOUS DISEASES. 8vo. $5 od RINDFLEISCH'S PATHOLOGICAL HISTOLOGY. $6 oo WARINGS’ PRACTICAL THERAPEUTICS, 2nd Am. Ed. 8vo. Cloth. $5 oc Leather. $6 oo SCUDDER'S SPECIFIC MEDICATION. 12mo. Cloth. TANNER's HANDBOOK OF OBSTETRICS. 12mo. WAN BUREN ON DISEASES OF THE RECTUM. Cloth. $1 5o FLINT'S EXAMINATION OF URINE. 12mo. Cloth. $1 oo VOGEL ON DISEASES OF CHILDREN. 8vo. Cloth. $4 5o BEARD AND ROCKWELL’S MEDICAL AND SURGICAL ECECTRICITY. 8vo. Cloth. $4 50 ATTFIELD'S MEDICAL CHEMISTRY. 12mo. Cloth. $2.75 * Leather. $3 25 BARTHOLOW'S HYPODERMIC MEDICATION. - Cloth. $1 5o TURNBULL’S DISEASES OF THE EAR. 8vo. Cloth. $5 od TILT'S CHANGE OF LIFE. 8vo. Cloth. $5 od NEUMANN'S HAND-BOOK OF SKIN DISEASES. Cloth. $4 oo ANSTIE ON NEURALGIA. 8vo. Cloth. $3 oo. PANCOAST'S OPERATIVE SURGERY. 4to., with many plates. $10 oo - HOOD ON BONE SETTING. 12mo. $1 50 RINGER'S HAND-BOOK OF THERAPEUTICS. 8vo. $4 oo HOLBROOK’S PARTURITION WITHOUT PAIN. I 6mo. $1 oo - PROCTER'S LIGHT SCIENCE FOR LEISURE HOURS.. 12mo. $1 75 BERNARD’S PHYSIOLOGY OF THE HEART. BARNES’ OBSTETRICAL OPERATIONS. 8vo. NICHOL’S FIRESIDE SCIENCE. 12mo. $1 50. WOHLER'S MINERAL ANALYSIS. 12mo. Cloth. $3 oo PLATTNER'S MANUAL OF ANALYSIS WITH THE BLOWPIPE. 8vo. Cloth. $7 5o JEFFRIES ON THE EYE. 8vo. Cloth. $1 oo MANSFIELD, A THEORY OF SALTS. 8vo. Cloth. $4 oo JEFFRIES ON THE SKIN. 8vo. Cloth. $1 oo GARDENING FOR PROFIT. 12mo. Cloth. $1 5o PRACTICAL FLORICULTURE. Izmo. Cloth. $1 5o FULLER'S SMALL FRUIT CULTURE. 12mo. Cloth. $1 WOODWARD'S COUNTRY HOMES. 12mo. Cloth. $1 5o DARWIN'S ORIGIN OF SPECIES. Izmo. Cloth. $2 oo ARTHUR'S TREATMENT AND PREVENTION OF DE- CAY OF THE TEETH. 12mo. $1 50 TYNDALL ON LIGHT AND ELECTRICITY. 12mo. $1 25. THE AMATEUR MICROSCOPIST. Small 4to. $4 75 BOOKS IN PREPARATION. BRYANT'S PRACTICE OF SURGERY. BARNES ON DISEASES OF WOMEN. ROBERTS ON RENAL DISEASES. GUERSANT, SURGICAL DISEASES OF WOMEN AND CHILDREN. - - Medical, Scientific, and other Catologues sent on application. Any book in the above list sent by mail or express, free of charge on receipt of price- 5o $2 5o $2 oo I 2 II* Q. I 2 IIl Qe 8vo. 5o cts. $4 5o So saddle-bass 65 West 4th Street, Cincinnati, Ohio. Fuſulfillſ. Wilſº twº Foster's 167 EAST 34TH-ST., NEm. Yo RK, By Special Appointment Electrical Instrument Makers to the New York State Hospital for Nervous Diseases, MANUFACTURERs of PowTABLE ELECTRO-MAGNETIC MACHINES, Portable Galvanic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, 1870, and May 30th, 1871. These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery Fluid. - |M|| |||||—|| ||||||} PEERMANIENT BATTERIEs, For Hospitals and General Practitioners, IETIECTIER,CIDIES. For Eye, Ear, Larynx, Nose, Uterus, Wagina, Bladder, Rec- tum, Feet, Phrenic and Sympathetic Nerves, Eleo- trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. IEXTRA (!TS FROM TEIE OPINIONS OF THE MOST JEMINIENT MIEMBERS OF THIº PROFESS / O N. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “Not HING CAN Exceed THE EfficIENCY AND convenience of this INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” We are authorized by Prof. Hammond to announce etn- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- roved and re-modified Instruments made by our Company. MEREDITH CLYMER, M. D., Prof. of Diseases of the Ner- vous System and of the Mind, &c., &c.—“I consider their Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prof. of Surgery, St. Louis:—‘ In neat- ness, compactness and efficacy, they can not be excelled.” ALFRED C. G ARRATT, M. D., Boston :-"In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” - - Similar Testimonials have been received from JOHN J. CRANE, M. D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A. MURRAY, M. D.; CHAS. E. BLUMENTHAL, M. D.; E. C. SEGUIN, M. D.; ALLEN MAYNARD, M. D., Cleveland, O.; Dr. C. WANNIE, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES KELLY, Fiorence, O.; Dr. JOHN BECKER, Brighton, Iowa; Dr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes- barre, Pa.; JOHN J. CALDWELL, M. D., Brooklyn, and many other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an Electrical Instrument for medical purposes. CALL OR SEND FOR CIRCULAR AND-PRICE LIST. FATENT Are furnished to Officers and Soldiers on Government a CCOunt. I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to .JAMES A. FOSTER, 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cincinnati, Ohio, or 172 Jef- ferson Avenue, Detroit, Mich- SAML. P. THOMAS T.A.. I I, OR, DEALER IN English, French and Scotch GOODs, 34 west Fourth street, cz.wcz.wwaz ra. Carriage Manufacturer, Nos. 9 and il East Sixth Street, bet. Main & Sycamore. I MAKE NOTHING BUT Jº Zºº,S 7" CA. 24 SAS' W’0 ſº M'. Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of - . . . LIGHT FAMILY CAFFIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenius, Nilssons &c., I make a very ex- tensive variety of light elegant designs of different cost and finish. In vehicles especially adapted to - - PHYSECHANS” {{SE, The annexed engraving Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. gº - - f . . . . . - The superiority of my light gentlemen’s buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price lists furnished on application. References Kºſs, to Dr. W. W. Dawson and all the leading ": “”. - . . - The Society then adjourned till half-past one o'clock P. M. Afternoon Session. The Society was called to order by the President, Dr. Ayres. . TIH. H. C.I.I NTT c. The following papers were read and referred to the Committee on Publication : By Dr. R. E. Haughton, of | Richmond—On the Pathology of Malignant and Semi- Malignant growths. By Dr. L. J. Wollen, of Moorfield —On an Epidemic of Parotitis (mumps) in Switzerland county. By the President—His anuual address. By Dr. T. C. Van Nuys, of Evansville—Researches in Arsenical Poisoning. By Dr. J, Thompson, of Indian- apolis—On Anomalies of Refraction and Accommo- dation. By Dr. Wilson Hobbs, of Carthage—On Ex- pert Testimony, the conduct of witnesses in court and the law which governs it. The last named paper elicited discussion by Drs. Wat- erman, Boyd and Moffit, after which Dr. Haughton moved that a committee of three be appointed to take into consideration the means to be used for the purpose of securing a definition by the laws of the State of what constitutes a physician or a medical expert—the com- mittee to report at this session. The motion prevailed. The Chair appointed Dr. R. E. Haughton as chairman of the committee, and upon nomination, Drs. L. D. Waterman and Wilson Hobbs were appointed as the re- maining members. - The Society then adjourned till 8 o’clock P. M. The Evening Session was occupied in the discussion of a series of resolutions to adopt measures of uniting all the various local Societies “to bring the entire profes- sion of the State into one harmonious body for the pur- pose of carry out the objects for which the Society was organized.” Second Day–Morning Session?. The Society came to order at 8 o’clock, the President in the chair. - - - The President appointed the standing committees. The Committee on Credentials and Membership made additional reports. The Committee on Medical Statis- tics was continued for the ensuing year. Dr. Thaddeus M. Stevens, of Indianapolis, read a paper on Legal Medicine. The paper advocated the formation of a corps of medical experts with a view to the relief of the profession in general from the embar- rassment of examination in court. It also advised that when physicians are called to testify on questions of sanity they confine their answers to the simple state- ment that the party is sane or insane, without attempt- ing to define the particular grade of insanity in any C2S6. The paper was referred to the Committee on Publica- tion. . Dr. C. E. Wright, of Indianapolis, read a paper on Diseases of the Eye and Ear. Referred to the Com- mittee on Publication. Dr. R. E. Haughton, of Richmond, from a special committee, submitted the following report: The Committee to whom was referred the subject of petitioning the Legislature, beg leave respectfully to re- port the following resolution; 274 [JUNE 8, 1872. TIEEE. cI.TISTI c. JResolved, That a committee of three be appointed to petition the Legislature of Indiana for the passage of an anatomical law, embodying such rights and protection, as well such wise restraints as shall prevent abuse in the study of anatomy, pathology and surgery as shall not subject the profession to odium, but which will enable its members successfully to qualify themselves for the practice of their profession, and fill the position of med- ical witnesses and experts in a satisfactory and honora- ble manner, thus facilitating the administration of jus- tice and promoting the interests of science. The report was concurred in and the resolution adopted. Dr. N. Field, of Jeffersonville, announced, with appro- priate resolutions, the death of a prominent member of the profession, Dr. Robt. Curran, of Jeffersonville. Dr. T. Parvin presented a communication from the Committee on Medical Education of the National Med- ical Association. Dr. T. M. Stevens, from the Standing Committee on Nominations, submitted the following report, which was concurred in : for President Joel Pennington of Milton. For Vice President R. E. Haughton of Richmond. For Secretary G. W. Woolen of Indianapolis. For Asst. Secretary W. J. Elstun of Indianapolis. For Treasurer J. T. Woodburn of Indianapolis. For Librarian A. W. Davis of Indianapolis. Also the delegates to the National Association and the various State Societies. Dr. N. Field, of Jeffersonville, read a paper on Thor- acentesis, which was discussed by Drs. R. N. Todd, of Indianapolis, J. I. Rooker, of Castleton, H. W. Passage of Peru, and R. E. Houghton, of Richmond. Dr. R. E. Houghton read a paper on Lithotomy, which was discussed by Drs. Comingor, Boyd, Water- man and Houghton. The Society then adjourned till 1% P. M. Afternoon Session. The Society was called to order by the President. Dr. Isaac Casselberry, of Evansville, read a paper on Electricity as a Cause of Disease, which was referred to the Committee on Publication. Dr. G. Sutton, of Aurora, offered, for adoption, the following resolution, which was adopted. Resolved, That we recommend to the Board of Trustees of the Indiana University that they introduce as soon as practicable, either into the scientific or medical depart- ment, a course of studies embracing comparative anat- omy, comparative physiology, and comparative path- ology—branches of science arising from the progress of knowledge, becoming daily of great practical importance in understanding the paleontology of our country, the zoology of our State, and the diseases which are pro- ducing such destructive ravages amongst our domestic animals. Dr. L. D. Waterman, of Indianapolis, read a paper on secondary effects of remedies, which, after discussion, was referred to the Committee on Publication. Dr. T. Parvin, from a special committee, submitted the following report: The committee to whom was referred the communi- cation from the Special Committee on Medical Educa- tion of the American Medical Association beg leave to present the following report: The communication embraces, as inviting the action of the Indiana State Medical Society, first, resolutions relating to the admission of persons to the practice of medicine, providing for the examination of such, for the compensation of examiners, and affixing a penalty for neglecting such examination ; and, second, a resolution relating to the admission of those desiring to study medicine to the offices of physicians or medical colleges. The report was first adopted afterwards reconsidered and tabled. - Evening Session. The Society was called to order by the President. The Secretary read a report by Dr. J. M. C. Adams, of Frankfort, on the prevailing diseases, and their treat- ment, of the Seventh Congressional District. On motion the paper by fobert Curran, M. D., en- titled Nosology of the diseases which have prevailed in Clark county, Indiana, since A. D., 1883, was read by its title, and referred to the Committee on Publication. The Secretary read the following list of special com- mittees to prepare papers for the next annual session: On Cerebro-Spinal Meningitis by Dr. Wm. F. Cady, of Lafayette. On the Correlation of Physical and Vital Forces by R. E. Haughton, of Richmond. Experimental Researches into the poisonous and chemical properties of Atropia by Dr. Thomas C. Van Nuys, of Evansville. On the Toxicological action of and examination for the Alkaloid, Thad. M. Stevens, M. D., of Indianapolis. On the Secondary Effects of Gunshot Wounds, by Dr. J. S. Gregg, of Fort Wayne. On Cerebral Meningitis as it prevailed in Montgomery county, Indiana, during the spring of 1872, by Samuel G. Irwin, M. D., of Craw- fordsville, Indiana. On Malignant Tumors, by Dr. L. D. Waterman, of Indianapolis. On Surgical Cases which have fallen under my observation, by J. S. McClelland, of Crawfordsville. On Chemico Legal Investigations, by Dr. P. McNab, of West Newton. On Cholera Infantum, by Dr. G. N. Duzan, of Zionville. On Dis- eases of the Eye and Ear, by Dr. C. E. Wright, of Indianapolis. On such subject as he may choose Dr. J. W. Hervey, of Oakland. - On motion of Dr. Waterman, the Secretary was au- thorized to add such further essays to the list as should be handed to him in time for publication in the printed proceedings of the session. The Society then adjourned till the third Tuesday of May, 1873. TROUBLES IN PARIS AND THE DOCTORS.–The ferocity displayed by the opposing troops in the struggles around Paris during the civil war was all but unparalled in history. Even in the most savage warfare the persons of the “Doctors” are, as a rule, held sacred. Not so, however, in the civil strife of last year. Attention has JUNE 8, 1872.] TIEEI IEH C T , T: INTIC . . 275 been drawn by a Paris journal to the fact that several Surgeons belonging to Val-de-Grâce were summarily executed by the Versailles troops in endeavoring to pro- tect a number of wounded insurgents near the Place St. Sulpice. The Government, it would seem, has at- tempted to hush up the affair; but the Dolbeau scandal has aroused some of the intractable students, and a private inquiry into the matter has commenced. M. M. Fano and Ferreogobi, two well known Surgeons, who had disappeared since the depression of the insurrection, are stated to have been among the victims.-Times and Gaz., May 11, ’72, A NEW PROFESSION FOR LADIES.—We learn from the German papers that a young lady recently presented herself at the Faculty of Medicine at Munich for exam- ination for a licence to practice as dentist. Being refused, she went to Erlangen. The question was here referred to the Government, who at once authorised the examin- ation, on the ground that it was absurb to exclude a person desirous to submit herself to authorised profes- sional tests of ability by reason of her sex. The young lady triumphed, and “is likely,” it is added, “to find immediate imitators.” - THE STRASBOURG FESTIVITIES.—The opening of the Strasbourg University took place on May 1, with cere- monies of great festivity. The President v. Möller de- livered an address in accord with the events of the day whereupon the foundation documents from the Emperor of Germany were exhibited and delivered with becoming ceremonies to rector Bruch. Telegrams of greeting were read from the crown prince of the German empire and from the German parliament. Rector Bruch then de- livered a most eloquent and brilliant address and he was followed by Prof. Springer the orator of the day. Wyss of Zünich expressed, in the name of Switzerland, the sympathies of his people with their heartiest greet- ings and good wishes. In the name of the Germans and on behalf of his university followed next Weitz of Göt- tingen when Tomaschek addressed the audience in the name of the Austrian universities calling out peal after peal of applause by his allusions to the union of the in- terests and efforts of Germany and Austria. Rector Buch in the name of the Strasbourg university thanked the various guests most heartily for their earnest participa- tion in the foundation ceremonies whereupon the exercises: closed with the national hymn and a grand feast.— Wien. Med. Presse, May 5, 72. —º-e—sº- German Therapy. [Periodically, the student of foreign literature has his sensibilities shocked by a contemptuous fling at German therapy at the hands of that gifted class of individuals, more especially to be found among our own fellow-countrymen who possess what is known as intuitive (!) capacities in curing disease. For the direct benefit of these natural bone-setters in therapy and the indirect protection it may afford to the educated of professional mankind in the future we insert the follwing extracts from a review of two Ger- man works on therapy, by the Huseman brothers of Göttingen and Nothnagel of Berlin, recently issued from press. . The London Practitioner (May, 1872,) from which the review is abstracted needs no statement from us to its “practical” character and standing]. “Not very long since we were talking to a medical man, by no means deficient in intelligence, on the sub- ject of the progress of therapeutics, when, to our consid- erable astonishment, our friend observed, in the tone of a matter of course, that England was the only country where practical medicine flourished, and that ‘foreigners' had no intelligent ideas about treatment whatever. It was impossible to answer that assertion; we were re- duced to silence; for it happened that only the day before there had been put into our hands the second of the works which head this notice; and the conception of Nothnagel, at any rate, as a writer inferior to our English authorities in intelligent ideas about treatment, was rather too ludicrous. We have never yet quite got over the shock inflicted upon us by the discovery that an educated English medical man could think in such a way; and our sensations on this subject have been revivified by the more recent publication of the mag- nificent work of the brothers Husemann. It is evident, in fact, that our medical countrymen are in general quite ignorant of many of the most important researches that have been made; and the result of comparing such a work as the new edition of Pereira (noticed by us last month) with the Husemanns' book more especially, is that one feels quite a pang of shame. “We would by no means be understood, however, as representing either of the works before us as faultless, or ideally complete; on the contrary, we have to urge against them several criticisms. But the fulness of knowledge, the patience of research, the open-minded fairness towards the labors of others, which their authors exhibit, form what should be a very useful lesson to English authors and students in medicine. * * * “On the other hand, all these defects are to a large extent compensated by the exceedingly clear and intelli- gent way in which the action of individual remedies is discussed. In each case (after the briefest introduction relating to the botanical or chemical sources of the medicine) there is a full account (a) of its physiological effects on healthy men, (b) ditto on animals, (c) the theory of its operation, as far as this may be known, and, finally, an aperçu of all the therapeutic powers to which it possesses any reputable claim. No English work on therapeutics has ever presented a view, any- thing like so complete, of the actions of medicines; and we feel sure that those of our readers who may take up the book will be considerably startled at the amount of information, sure to be almost entirely new to them, which they will meet with. The article on bark and 276 [JUNE 8, 1872. TIEH. H. C.I.I.INTI C. its derivatives, for example, is one to which we have no parallel at all in English therapeutical literature, for concise statement, in a few pages, of the result of a very large number of most important researches. “We must conclude, as we began, with the remark that these two excellent works of the Husemanns and of Nothnagel surpass anything of the kind which we possess in this country. They are very far from being perfect; there are many omissions in them (some, by the way, involving injustice to English observers), and in neither of them is the plan all that we can approve; but at least they will serve to convince all that read them carefully of the desperate need there is for setting up a standard work, in this neglected subject of thera- peutics, immensely higher than anything we have as yet been accustomed to.” —º-e—º- C. L.INI ICAL, MIEM [O] RNAIDA, XYLOL IN SMALL-POX.—Conclusions of an extensive article with hospital statistics by Dr.A. Buckart (Stutt- art). g *in varioloid and the simpler forms of variola (variola discreta) xylol is at least superfluous as no medicament is able to hasten the eruption of the pock, to abbreviate its individual stages or to induce a speedier recovery. 2. In the confluent, pustular forms with grave con- stitutional disturbance and high fever, xylol has as little essential influence on the course of the fever as the antipyretics proper. In these cases death occurs not only from the enormous increase of temperature, but also from the extensive interference with cutaneous perspiration, as in extensive burns. Any effort from xylol here would only be possible by a compensation for the checked insensible perspiration. Xylol has, then, neither an antifebrile nor a specific action. On the other hand by its influence on the eruption in the throat and on the attendant angina it may act as a life-saving agent. In this regard it is far superior to the chlorate of potash or lime, and on this account xylol is to be considered as an important, an indispensable remedy in the treat- ment of pustular pocks. Here comes in also its deo- dorizing, disinfecting action. 3. Of the septic forms there are a few very insolated cases which recover without any treatment at all. In the grave cases all treatment is useless-Berlin Klin. Wochenschr., April 29, '72. TEST FOR THE PURITY OF CREASOTE.-The wood- creasote of Reichenbach has long been known as a thera- peutic and antiseptic agent of considerable value. For it has recently been substituted in commerce, phenic or carbolic acid, a substance of different properties. To distinguish those bodies, Mr. Thomas Morson, of the firm of Morson and son, has discovered a very simple test. It is only necessary to mix the suspected Sample with pure glycerine; pure creasote is insoluble in this medium ; carbolic acid makes a bright Solution, and, when present in considerable quantity, it make creasote also soluble in the mixture.—Brit. Med. Journ. May 18, '72. ADENOMA.—A most extremely interesting case of this affection is reported from the Charité, Paris. Annette L., at. 58, cook, robust health, regular habits. Neck enormously swollen, almost obliterated by a large number of glands, indurated, indolent, not adherent to skin, without fluctuation. This ganglionic chain passed beneath the clavicle, deflecting the larynx in the neck away from the median line. Obesity supervened, with dyspnoea and alteration of the voice. Iodide of potassium had not the least effect. On Nov. 21, M. Lannelongue injected into the centre of the largest tumors a few drops of iodine which he had already used in two lighter cases with slight but sensible amelioration. These injections, repeated in this case on two subsequent occasions were without effect. The malady made frightful progress. The tumors rapidly enlarged; dyspnoea increased; sibilant pulmo- nary rales; increased displacement of the larynx; face cyanosed; limbs cold and livid. Tracheotomy was con- sidered but rejected as it was thought that the pressure on the recurrent nerves would still maintain the dyspnoea. Resort was had to enucleation. Some twelve of the larger glands were removed under chloroform. Great improvement followed; cyanosis and dyspnoea disap- peared; the limbs became warm; condition confortable. Dec. 4th and 5th secondary hemorrhage ensued, to be repeated on several occasions within a few days. The hemorrhage was abundant and alarming. It was venous blood. Its source was finally discovered. The internal jugular was ligated. The patient died exsanguine. On autopsy it was found that all the glands of the neck were enlarged down to the base of the cranium. The coats of the internal jugular were opaque, granular and ulcerated. The ligatures had not cut through a single coat. The section was made with great care. Lymphoid productions were found in the pleura, the liver, the spleen and the vertebrae. 1. Clinical and microscopic examination demonstrate that we had to deal with the well known affection which Trousseau designates adenia, but which we shall term lymphadenomia. 2. As frequently occurs, this alteration commenced in the neck. The cervical ganglions first undergo hypertrophy without appreciable cause. Later this alteration successively invades the glands of the thorax and abdomen. 3. The histological tissue of these ganglions is repro- duced at a distance, in the spleen, liver, pleura, even in bone. Wirchow in the third volume of his work on tumors casts doubt on the lymphoid nature of these productions in the pleura and the spleen. With this observation we establish its existence. - 4. Notwithstanding the grave organic lesions, our patient preserved her embonpoint to the end; a fact worthy of note. - 5. This disease is formidable from the start. First, because patients do not recover. Medication at times can only temporarily arrest its progress. It may ad- vance, secondly, so rapidly, as to destroy life in a few months. - 6. We cannot terminate these remarks without noticing the fact that though the internal jugular vein remained open for more than half an hour yet no air penetrated to its interior. The autopsy showed that there was not the least bubble of air either in the veins or in the right side of the heart.—Gaz. des Hopitawa; Apr. 9–11, ’72. - - —sº-o-º- I HIOMIE NEWS. DEATHS FROM SMALL-POX still continue at the rate of 12-15 per week. - - THE STATE SOCIETY DELEGATIONS depart for Ports- mouth on Monday afternoon. A profitable and a good time is anticipated. o Po R. L.E. s.s A.N D F A LATA H L E. In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERs & BARTLETT, of Portsmouth, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. - - - Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachitic Affections, in Chronic Rheumatism, &c. The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated, The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. wo. 7 resr rovara scºrer. PIKE's OPERA, HOUSE BUILDING, Importer and Dealer —“I N-- Diamond and Gold Jewelry, - * -- Watches for Ladies and Gentlemen, Sterling Silver - Tableware, Bronzes, Antique and Modern; Marble and Bronze Clocks, M ar b le Statu a ry, FAN cºr Coo: Ds, GENERALLY. # wº š § §Nº. § 5.§ s sº cº-º : º º Fº º: & F- $35Sº Essº * 3ºE-> PºstS ESºs- ºšºBºš º- * §§ -c = … *†† G |. | º ºf . . . . s º : - ºff: | j f º #: #ººl; |# | #|| s:######S. # ;P-ºº: | ( §º |..}}| #º ####|| ºº:: ; : E iſ jº º- * -º * * lſº # ºffilii #. 15.3 - #: Žiº º |||}; Sº 5 º #ºº sº # ºº::= §:# - Žiž; 42 % - º: lſº % % * * º % * “º Ezza ºf º: ſ: 2. 3/2^ º §ºſºft/ º-> ==ESs ºf º * … "… 2. L- 3ºEß,72% ºf 2: 2,2/.352." - Śº:=#2 Zºº, **º-º-º/ 32 ZZ - º:##=# º/A º yº º Aº, E - % :===ºſº, fl. ſº غ: %2-ºº::=>< *@ſº º º, ºr . . * #3:2::=#ºtº2 - #º: #}} % :- sºft.*::= §.º.º. -- / 22 S. s-Nº-E--> > <>7. Z 22. =s======sº Ž2. * -- GooD s AMARITAN HOSPITAL. - The GOOD SAMARITAN HOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner of sixth and Lock streets. It is handsomely furnished throughout, and is provided with all the necessary ap- pointments of a First-class Hospital. Porticoes, halls and abundant windows secure that full and free ventilati Service is furnished by the Under the Superintendence of the We with commanding views, surround the whole house, and wide on which is so essential to health and comfort. stsTLRs or charity, Il-known SISTERANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. - The regular Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each Professor presiding over his own especial department. Patients may, however, select from the regular profession of the city any physician of their choice. - The GOOD SAMARITAN HOSPITAL presents extra inducements to Invalids throughout the State as a safe and quiet asylu some stay is necessary in after treatment. Rooms vary in price, according to the character of appoi m in any case of protracted illness, or in cases, more particularly, requiring Surgical Operation, where intments necessary and service required, ranging, iº general terms, between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand of service. Bºy" Address, SISTER ANTHONY, EIospital of the Good Samaritan, Corner of Siacth and Lock Sts., Cincinnati. Ohio- F. E. SUIRE, E. S. WAYNE sºlº- JAMES FOSTER, Jr. & CO. [ESTABLISHED, 1836.] Importers and Manufacturers of Optical and Physical Instruments, Keep constantly on hand first-class English and French Microscopes, First-class Objects and Microscopical Apparatus of every descrip- tion, Medical Batteries, Thermometers, IHydrometers, Urinometers and Chemical Glass Ware. Special attention given to adapting the best spectacles to all conditions of sight. We take pleasure in showing the latest novelties from the best Euro- pean and American manufacturers. JAMES FOSTER, Jr. & Co., S. W. cor. 5th & Race Sts., Cincinnati, O. TXTER, S-INT. TMI_A_TER/SIET’S àw gºmº A "ſº zºº a Cºyº C޺ & - C޺ No. 758 BROADWAY, New York HAVE been in the habit of applying and recommending the Truss manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined. LEWIS A. SAY RE, M. D. Surgeon, Bellevue Hospital. From Prof. Willard Parker to S. D. Townsend, M. D., Surgeon to the Massachusetts General Hospital, B EG leave to state for the benefit of all concerned, that I have known Dr. S. N. Marsh the last fifteen years. sº I am in the constant habit of sending my patients to him for treatment: I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with any of the risks to the patient that exist in many of the plans suggested and attempted to be carried into execution. I have confidence in Dr. Marsh as a gentleman of honor and integrity, and as such recommend him to the members of the medi- cal profession generally. WILLARD PARKER, M. D. Professor of Surgery, New York City f Dr. S. N. Marsh's Patent Radical Cure Truss and all other kinds of Trusses, Shoulder Braces, Supporters, Elastic Stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Cure Truss Offices of S. N. MARSH & CO., No. 2 Vesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. OPPOSITE THE HIGH STEEPLE, fºr Agonts for Clement's Patent Artificial Legs. F. E. suire & Co., WHOLESALE DBUGGISTS, IMI A. IN TJ” ET AL C T TJ IF, IT INT G- - £Hexists AND PHARMAceutists, CINCINNATI, OHIO. Have constantly on hand a full assortment of syex,xec 90'xex) ox{UGS ANOO IVX)expxc)(N)es, cºerºxx.cAx, AeeARAºcus, TESTS, MEDICAL, GLASS WARE, &c., &c., And solicits the patronage of the trade and profession. We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, Made in accordance with the U. S. P. and other recognized authori- ties. - - E"INIHE AND EARH, CHEMICALs, Of the popular class of preparations known as IH, T, IDXIIIER, S, Wemanufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. Bitter Wine of Iron, An excellent Chalybeate and tonic, Wine of Mºon, &c AGENTS FOR BULLOCK & CRENSHAW's Sugar-coated Pills and Granules. Price Lists of preparations and of Sugar-coated Pills sent by Mail upon application. The long standing and well and widely known repu- tation of our house we offer as a guarantee for the reliability of our preparation, and the quality of the goods sold by us generally. * List of Pharmaceutical Preparations, MANUFACTURED BY Jonºv wreznº anorman PRILADELPHIA. _*- ELIX. PHOS, IRON, QUININE AND STRYCHNIA, - fixir of GENTIAN FERRATED, ELIXIR WALERIANATE OF AMMONIA, * (Goddard’s Formula,) ELIXIR VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, • Iron, with Phosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Iron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK, t º ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER WINE OF IRON, Citrate of Iron and Peruvian Bark, - - FERRATED CORDIAL ELIXIR, ELIXIR CALISAYA BARK, WINE AND BISMUTH, ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, TASTELESS COD LIVER OIL, TASTELESS COD LIVER OIL. FERRATED, - BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and sherry wine, ELIXIR WALERIANATE OF STRYCHNIA, WINE OF PEPSIN, SYRUP SUPERPHOSPHATE OF IRON, { ELIXIR OF BISMUTH, CowP. FLUIDEXT, EUCHU AND PAREIRA BRAVA. STUTEPEPOSITOTER, TIES. Rectum, Waginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great eare, and of every variety of combination. Lists sent on application. SPONGE TENTS.—For the Urethra, of every size and Btyle, made of finest quality of sponge. u ſ E - Fº = *— . §º ºft %&# Zºś CINCINNATI. E" A C Uſ IT, T Y - J A M E S G R A H A M, M. D., DE AN, Professor of the Theory and Practice of Medicine and Clinical Medicine. ROBERTS BARTHOLOW, M.D., W. W. DAWSON, M.D., - Professor of Materia Medica and Therapeutics. Professor of Principles and Practice of Surgery and Clinical Surgery. W. H. GOBRECHT, M.D., Professor of Anatomy. - T. A. REAMY, M.D., P. S. CONNER, M.D., Professor of Obstetrics and Diseases of Children. Professor of Surgical Anatomy. JOHN L. CLEVELAND, M.D., JAMES T. WHITTAKER, M.D., Demonstrator of Anatomy. Professor of Physiology. SAMUEL NICKLYS; M. D., CHARLES KEARNS, M.D., Professor of Physics and Medical Chemistry . 488istant to the Chair of Surgery. W. W. SEELY. M. D., IP roſessor of Diseases of the Eye and Idar, and Secretary of the Faculty •- ~ T. LOUIS Brows, M. D., Prosec (or of Anatomy. J. NoHLE, Janitor, College Building, Sixth St., bet. Wine and Race. PUBLISHED EveRx saturday. T E. R. Ms—$2.00 a Year, Invariably in Advance. All Communications, relating to Publications must be addressed to the Editoff . . . . All Communications. relating to Business, Subscriptions, Advertisements, etc., to the Treasurer. . > - - -ºf vol.2: . . . . of No INNAT1, J U N E 15, 1872. No. 24. **. &: cº-º: r’ *::::::::::::… *}|| || || || ||M|||||||}|, .. w, w, smely, M. D., - - - . - - * - •. , & - - º No. 118 West Seventh Street, Cincinnati. . . . . . . . . . . . 0 all - erº, 0 , “ . . . . . . . 3 - - - . . U. º () Pinted and Published by THE CLINIC Publishing company, & . . . —ºriº |Hºltål Hillſ; and lºſſ ºf Him, **º 92 FOURTH STREET, 1. . . " • . S.----------------- º • opposite Post office, o o N T E N T S ser The Oldest Established Hat Hºuse on the street.-ès — *Fine Silk Hats, Standard Quality $6.00. origiNAL ARTICLEs , , , |--— . Rºrontos orology, by W.W. Seely, M. D....…. 277 CEPHALAToMIA, by D. Cunningham, M. D. 280 - Boğan. - 10) ºf Sizºº ANDºd # *: *ENGRAV, º TRANSLATION . stretching of the Cervical Nerves for Relief of Cramp, by Prof. - Nussbaum, (From Schmidt's Jahrbücher, Aprij, ’72.................. 281] ... -x. . . . - The Influence of the Mind on. the Body, by Daniel H; Tuke, M. D. (From the ºurn; Mental Science, London, Apr., *72.).....:......282 screw TIFIC NOTES: , , ; * - - * - -- J. TAFT, . . . . - W. TAFT. Position of the Epiglottis as a Sign of Probable Longevity—Preser- -------------, - sº - - - - vation of Subjects for Dissection—Tolerance of Tobacco......285-286 - Editor Dental Register - MIE DICALL NEWS : - Army Medical School in Japan—Census Statistics of the Three | - J. : & W. TAF T, i Learned Professions—West Virginia State Medical Society...... 286 CLINICAL MEMORANDA - Tincture of Iodine in Womiting—Cimicifuga Racemosa as a Preven- ID E. i | N | | - I s | S' | I S tive of Small-Pox–Parenchymatous Injections into Tumors— s - - - Amblyopia from Masturbation—Treatment of Spermatorrhoea— Removal of the Kidney........................... ........ 286-287| on. “ ” -- || 17 WEST FOURTH STREET, - - - - - - - - - - Our readers will miss the usual report of the proceed- ings of the Academy of Medicine. The absence of members attending the State Medical Society was such that it was deemed best to postpone business till next. monday evening. . - - We give this week a novelty in the way of surgical * practice by Prof. Nussbaum of Munich, in which the cord was exposed and stretched for the relief of anaes- - thesia and cramps. A Monthly Journal, The interesting article showing the influence of the º mind on the body is continued from last week. Our space would not permit us to give the minutes of the West Virginia State Medical Society in full. Devoted to the Interests of the Dental Profession, CINCIN NATI, O. CONTAINING 48 PAGES, WILSON BRO's. S HIRTS Made to order of N. Y. M. Muslin and 2300 || HEAVY Linen, per dozen - - - $36 00 Wamsutta Muslin and 2100 HEAVY Lin- " en, per dozen - - - - - - - - 38.00 Wamsutta Muslin and 1900 Linen, per doz. 30.00 Lonsdale Muslin and 1700 Linen, per doz. 27.00 First three. qualities have ALL LINEN Cuffs and Neckbands. At above prices Cuffs are attached. Same quality of our own manufac- ture, ready-made, $3 per dozen less. - Perfect satisfaction given or money cheerfully refunded. . . . . Also import and Manufacture Men's Furnish- ing Goods. - Pike's Opera-House, Fourth Street, Cincinnati; 92.1 Wabash Avenue, and SS West Washingtons & Street, Chicago. CAMARGO MANUFACTURING COMPANY, MANUFACTURERS AND IMPORTERS OF AND Window Shades, & Wasr Fovarw Szºzº, was rap—admists. School Teachers, Students AND OTHERS, Can find light and healthful employment for the Summer, by engaging in the sale of our valuable and very popular works. One lady teacher just commencing work for us, reports net profits for last week at ForTY DoILARs—many others doing equally well. Large commissions or liberal salary as preferred. For particulars, address NETTLETON & CO., . . . 161 Elm Street, CINCINNATI, OHIO: P. S.—We will make “spºCIAL TERMs” to medical stu- dents, who are “working their own way through college.” BASCOM & CARTENTER, |Stationers, Printers Blank Book Manufacturers, 136 VINE sº CEREET, - s\ssWA\\\, CINCINNXT, O, H. H. BRENEMAN, Proprietor. E. D. ALBRO & BRO. IMPORTERS AND MANUFACTURERS OF |FOREIGN and DOMESTIC WOODS In Veneers, Boards and Plank, frtaint-Maºri', 'al-Builibri'ami Hi-Hinº The only house in the Western country that saws Spanish and Mexi; can Cedar for Cigar-Box Makers. We import our own wood direct, and can sell at prices to compete with any and everybody. - Also saw and keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. Office and Warerooms, #36 and 138 West Second Street, * Veneer Mill, 501, 503, 5ii, 513 & 515 W. Sixth St., CINCINNAT1, - Sº r FOSTER, Jr. [ESTABLISHED, 1835.] Importers and Manufacturers of Optical and Physical Instruments, English and French Microscopes, First-class Objects and Microscopical Apparatus of every descript. tion, Medical, Batteries, Thermometers, Hydrometers, Urinometers and Chemical Glass Ware. given to adapting the best spectacles to all conditions JAMES dº. CO. Special attention of sight. . We take pleasure in showing the latest novelties from the best Euro- pean and American manufacturers. - ... • * JANIES FostER, Jr. & Co., S. W. cor. 5th & Race Sts., Cincinnati, O. D.R. 5.N.M.A.Rs.H.’s * ~ * . . Aºtº - - , No. 758 BRoapw AY, New York I HAVE been in the habit of applying and recommending the Truss manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined. WIS A. SAY RE, M. D. Surgeon, Bellevue Hospital. £º º } º From Prof. Willard Parker to S. D. Townsend, M.D., Surgeon to the Massachusetts General Hospital. . BEG leave to state for the benefit of all concerned, that I have known Dr. S. N. Marsh the last fifteen years. * * * I am in the constant habit of sending my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with any of the risks to the patient that exist in many of the plans suggested and attempted to be carried into execution. I have confidence, in Dr. Marsh as a gentleman of honor and integrity, and as such recommend him to the members of the medi- cal profession generally. WILLARD PARKER, M. D. . Professor of Surgery, New York City Dr.S. N. Marsh's Patent Radical Cure Truss and all other kinds of Trusses, Shoulder. Braces, Supporters, Elastic stockings,. Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Qure Truss Offices of S. N. MARSH & CO., No. 2 Wesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. OPPOSITE THE HIGH STEEPLE, * Agents for Clement's Patent Artificial Legs. *—— F. E. SUIRE, E. S. WAYNE IF. E. Suire & Co., WHOLESALE DRUGGISTS, IM. A. INT UT EP A CT U ER, I NT G- £Hemists AND FHAR MACEUTISTS, CINCINNATI, OHIO. Have constantly on hand a full assortment of skex, Ecºexex, Yokkö GS ANYO IVXXExpxc)(N)es, ck{xeryx)(CAX, APPA)3A%Us, TESTs, MEDICAL, GLASS WARH, &c, &c., And solicits the patronage of the trade and profession. We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, alſº in accordance with the U. S. P. and other recognized authori- ºiGS. FINHE AND EARE CHEMICALs, Of the popular class of preparations known as E. T., IL&T I IR, S, We manufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. - Bitter wine of Iron, An excellent Chalybeate and tonic, Wine of Iron, &c AGENTS FOR BULLOCK & CRENSHAW'S Sugar-coated Pills and Granules. Price Lists of preparations and of Sugar-coated Pills sent by Mail upon application. The long standing and welf and widely known repu- tation of our house we offer as a guarantee for the reliability of our preparation, and the quality of the goods sold by us generally. Hiſtºl Muſº ºwl nFoster's 167 EAST 34TH-ST., NEW Yo 1; K, By Special Appointment Electrical Instrument Makers to the New York State Hospital for Nervous Diseases, MAN UF ACTURERS OF PORTABLE ELECTRO-MAGNETIC MACHINES, Portable Galwanic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, 1870, and May 30th, 1871. These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery I'luid. |M|| |||||—|| || |||||||} PER MAN ENT BATTERIEs, For Hospitals and General Practitioners, IET IIECTIE, OTDIEBS. For Eye, Ear, Larynx, Nose, Uterus, Wagina, Bladder, Rec- tum, Feet, Phrenic and Sympathetic Nerves, Elec. trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. º —->O-3-O->- EXTRA (17'S FRONT TH F O PIN TON'S OF THE MOST IEIMIN ENT ME M BERS OF TEM Jº PROFESS / ON. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “Nothing cAN EXCEED THE EFFICIENCY AND CONVENIENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” We are authorized by Prof. Hammond to announce etn- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- proved and re-modified Instruments made by our Company. Al EREDITH CLY MER, M. D., Prof. of Diseases of the Neº- vous System and of the Mind, &c., &c.—“I consider theºr Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prof. of Surgery, St. Louis:—‘ In neat- ness, compactness and efficacy, they can not be excelled.” ALFRED C. G ARRATT, M. D., Boston :-" In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” Similar Testimonials have been received from JOHN J. CRANE, M. D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A. MURRAY, M. D.; CHAS. E. BLUMENTHAL, M. D.; E. C. SEGUIN, M. D.;. ALLEN MAYNARE), M. D., Cleveland, O.; Dr. C. WANNIE, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES KELLY, Florence, 0.; Dr. JOHN BECKER, Brighton, Iowa; Dr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes- barre, Pa.; JOHN J. CALDWELL, M. D., Brooklyn, and many other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an Electrical Instrument for medical purposes. himlitial Are furnished to Officers and Soldiers’ on Government account. I claim to have combined such improvements in ARTI- FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. . It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb-why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMES A. FOSTER, 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cincinnati, Ohio, or 172 Jef- ferson Avenue, Detroit, Mich. SAML. P. THOMAS T.A. I. L. O.R., DEALER IN Štſ. § (ſ) º g English, French and Scotch 34 West Fourth Street, CALL OR SEND FOR CIRCULAR AND PRICE LIST. crwcz.w.wºrr. Wm. Wilson McGrew, wo. 27 mºst rowarm Szwarr, Pike's opera House BUILDING, In porter and Dealer k • —-areaea I N weeee- Diamond and Gold Jewelry, watches for Ladies and Gentlemen, ** . Sterling Silver Tableware, Bronzes, Antique and Modern; Marble and Bronze Clocks. Marble Statuary, FAN cºr Coons, G E N E R A L L Y. . DIVIDED MEDICINES, 2REPARED BY The Divided Medicine Com’y, CINCINNATI, OHIO. The Company have the hônor of bringing to the notice of the Profession, this NEW AND ExCEEDINGLY PRACTICAI, METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. f The Divided Medicines are prepared by FREDERICK KRAUs, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MORE. The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every square will consequently contain accurately measured quantities. | But not only SoLUBLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINES. =: *- *-*-* *- -º-º-º-º-º-º-º- - , ºvº-wºm-- x -- :--> -- tºt- -º-º-º-º: dº- * **- -> → ~ Jº" - - *. * * • . - * ſº =s*- 'ſº *-*-*-*-*. * - -º-em- ºf 23 *º-m-m-m- º –Tº-c --- - -t- ...-am-ºn-º-º-º-º-ºm- º # === --ºft. #. E: =#|| jºi jºiº #|| º º º jºiº º: ºš |††† | ...," A. D º : ; % ſ - %ſ |É # rº- §§sºž * -- sº S2: ... Zºº - - Bºž %22%2. - º 2.222 Ž £y!!º º E- -->E-E_º -> -: º: E E-E- =sº - - >º- 2//Wºº, a-ºº: *- -> E: Good sa MARITAN Hospita L. The GOOD SAMARITAN HOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner of Sixth and Lock streets. It is handsomely furnished throughout, and is provided with all the necessary ap- with commanding views, surround the whole house, and wide pointments of a First-class Hospital. Porticoes, entilation which is so essential to health and comfort. halls and abundant windows secure that full and free V Service is furnished by the sts.TLRs or CHARITY, Under the Superintendence of the well-known SISTER ANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. endance of the house is supplied by the Faculty of the Medical College of Ohio, each The regular Medical Att ent. Patients may, however, select from the regular profession Professor presiding over his own especial departm of the city any physician of their choice. The GOOD SAMARITAN HOSPITAL presents extra inducements to Invalids throughout the State as a safe and quiet asylum in any case of protracted illness, or in cases, more particularly, requiring Surgical Operation, where some stay is necessary in after treatment. Rooms vary in price, according to the character of appointments necessary and service required, ranging, in general terms, between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand of service. . . ' - gas-Address, - . SISTEER ANTHONY, Hospital of the Good Samaritan, Corner of Siacth and Lock Sts., Cincinnati. Ohio. William Autenrieth, ROBERT CLARKE & CO's. No. 71 WEST sIXTH stEEET, BETWEEN WALNUT AND WINE, CINCINNATI, OHIO, MANUFACTURER OF AND DEALER IN {I}|| || || ||||||||ſ. Abdominal Supporters, Trusses, CLUB-F00T SHOES, SPINAL APPARATUS, ETſ Koeps constantly on hand a full variety of Metalic and Rubber Syringes, Stomach Pumps, Etc. STOCKINGS FOB WARUCOSE WEDNS, Special attention given to the fitting of Apparatus for Deformities. Bay Agent for DR. L. A. BABCOCK'S $ilver Uterine Supporter, -AI,SO— DR. AHL's POROUS FELT SPLINTS, | * S TH> T, IN T S -AND- —A LSO– T) A. Y. * S HAMMOND ON NERVOUS DISEASES. |WOGEL ON DISEASES OF CHILDREN. 8vo. BARTHOLOW'S HYPODERMIC MEDICATION. LIST OF NEW MHL iBTH in Mällis Hill; GREEN'S PATHOLOGY AND MORBID ANATO MY, 8vo. Cloth. $2 5o - DUCHENNE'S LOCALIZED ELECTRIZATION. 8vo. $3 oo DILLENBERGER ON WOMEN AND CHILDREN'S DIS- EASES. 12mo. $1 75 - BENNETT ON PULMonoRY CONSUMPTION. 8vo. $1 5o FIRST HELP IN ACCIDENTS. 12mo. $1 50 BEASLEY'S DRUGGIST RECEIPT BOOK. 8vo. $3 go ECHEVERRIA ON EPILEPSY. 8vo. Cloth. $5 od HOWE ON EMERGENCIES. 8vo. $3 oo 8vo. $5 od RINDFLEISCH's PATHOLOGICAL HISTOLOGY. $6 oo WARINGS' PRACTICAL THERAPEUTICS, 2nd Am. Ed. 8vo. Cloth. $5 od Leather. $6 oo - SCUDDER'S SPECIFIC MEDICATION. 12mo. Cloth. TANNER'S HANDBOOK OF OBSTETRICS. 12mo. WAN BUREN ON DISEASES OF THE RECTUM. . Cloth. $1 5o - - FLINT'S EXAMINATION OF URINE. 12mo. Cloth. $1 oo - - Cloth. $4 5o BEARD AND ROCKWELL’S MEDICAL AND SURGICAL ECECTRICITY. 8vo. Cloth. $4 50 ATTFIELD'S MEDICAL CHEMISTRY. 12mo. Cloth. $2.75 Leather. $3 25 * $2 50 $2 oo I 2 Iſl O. I 2 II] O. Cloth. $1 5o - TURNBULL’S DISEASES OF THE EAR. 8vo. Cloth. $5 od TILT'S CHANGE OF LIFE. 8vo. Cloth. $5 oc NEUMANN'S HAND-BOOK OF SKIN DISEASES. Cloth. $4 oo * ANSTIE ON NEURALGIA. 8vo. Cloth. $3 oo. PANCOAST'S OPERATIVE SURGERY. 4to., with many plates. $10 oo - HOOD ON BONE SETTING. 12mo. $1 50 RINGER'S HAND-BOOK OF THERAPEUTICS. 8vo. $4 oo HOLBROOK’S PARTURITION WITHOUT PAIN. 16mo. 8vo. $1 oo PROCTER'S LIGHT SCIENCE FOR LEISURE HOURS. 12mo. $1 75 - BERNARD’S PHYSIOLOGY OF THE HEART. BARNES’ OBSTETRICAL OPERATIONS. 8vo. NICHOL's FIRESIDE SCIENCE. 12mo, $1 5.o. WOHLER'S MINERAL ANALYSIS. 12mo. Cloth. $3 OC 5o cts. $4 5o |PLATTNER'S MANUAL OF ANALYSIS WITH THE BLOWPIPE. 8vo. Cloth. $7.50 JEFFRIES ON THE EYE. 8vo. Cloth. $1 oo MANSFIELD, A THEORY OF SALTS. 8vo. Cloth. $4 oo JEFFRIES ON THE SKIN. 8vo. Cloth. $1 oo GARDENING FOR PROFIT. 12mo. Cloth. $1 5o PRACTICAL FLORICULTURE. 12mo. Cloth. $1 50 FULLER'S SMALL FRUIT CULTURE. 12mo. Cloth. .$1. 5o WOODWARD'S COUNTRY HOMES. 12mo. Cloth. $1 5o DARWIN'S ORIGIN OF SPECIES. 12mo. Cloth. $2 oo ARTHUR's TREATMENT AND PREVENTION OF DE- CAY OF THE TEETH. 12mo. $1 5o TYND ALL ON LIGHT AND ELECTRICITY. THE AMATEUR MICROSCOPIST. Small 4to. BOOKS IN PREPARATION. BRYANT'S PRACTICE OF SURGERY. BARNES ON DISEASES OF WOMEN. ROBERTS ON RENAL DISEASES. GUERSANT, SURGICAL DISEASES OF WOMEN AND CHILDREN. - Medical, Scientific, and other Catologues sent on application. Any book in the above list sent by mail or express, free of charge on receipt of price. 12mo. $1 25 $1 75 : “… S. W. Elliott’s Saddle=bags 65 West 4th Street, Cincinnati, Ohio. st of Pharmaceutical Preparations, Jonºv wrera e anorarn, PHILADELPHIA. ELIX. PHOS, IRON, QUININE AND STRYCHNIA, ELIXIR OF GENTIAN FERRATED, ELIXIRVALERIANATE OF AMMONIA, • (Goddard’s Formula,) ELIXIRVALERIANATEAMMONIA AND QUININE, ELIXIR OF THE FYROPHOSFEATE OF IRON, - - FERRATED ELIXIR OF CINCHONA, ELIXIR OF CALISAYA BARK, ". oice Aromatics, ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, - COMPOUND SYRUP OF PHOSFHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER WINE OFIRON,... - FERRATED CORDIAL ELIXIR, ELIXIR CALISAYA BARK, WINE AND BISMUTH, ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, - - TASTELESS COD LIVER OIL, TASTELESS COD LIVER OIL. FERRATED, . . . . . . . . . . . . BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and sherry wine, ELIXIRVALERIANATE OF STRYCHNIA, WINE OF PEPSIN SYRUP SUPERPHOSPHATE OF IRON, - - J ELIXIR OF BISMUTH, COMP. FLUIDEXT, BUCHU AND PAREIRA BRAVA. STUIFE” OSITOIR. II ES. Rectum, Waginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great eare, and of every variety of combination. Lists sent on application. - SPOINGE TENTS.—For the Urethra, of every size and 8tyle, made of finest quality of sponge. º W . - W s Nº. Å; tº: . |. | sº jº, A. . ºº lººs t ſº tº tº sº * E::::::::::::-º-º: 2: 2& ZººZºº ... || ; mº Filmº #. § º- - iſ . . i. Nºll. º, i. ºſº".º ; C- º- º: -t§* ..-º.. sºdiºº- º-*. |ºº -* i º -ſº- ſº s- = H º £- ſº - ŽS ºf | #st; : CINCINNATI. - FA C U L T Y. J A M E S G R A H A M, M. D., D EA N, JProfessor of the The Ory and Practice Of Medicine and Clinical Medicine. ROBERTS BARTHOLOW, M.D., . . W. W. DAWSON, M.D., Professor of Materia Medica and Therapeutics. W. H. GOBRECHT, M.D., jºs - I’rofessor of Anatomy. . T. A. REAMY, M.D., P. S. CONNER, M.D., Professor of Obstetries and Diseases of Children. Professor of Surgical Anatomy. '*'. JAMES T. WHITTAKER, M.D., I’rofessor of Physiology. Professor of Principles and Practice of Surgery and Clinical Surgery. JOHN L. CLEVELAND, M.D., Demonstrator of Anatomy. SAMUEL NICKLY'S, M.D., - CHARLES KEARNS, M.D., Professor of Physics and Medical Chemistry Assistant to the Chair of Surgery. WV. V. S.E.E.T.Y., M. D., Professor oſ IDiseases of the HSye and FCar, and Secretary of the Faculty *--~ T. LOUIS BROWN, M. D., Prosec (or of Anatomy. - E. NoBLE, Janitor, College Building, Sixth St., bet. Vine and Race THE CLINIC. PUBLISHED EVERY SATURDAY. - º * E R MS-$2.00 a Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editor: All Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer. C IN C IN N ATI, * J U N E 22, 1872. No. 25. Vol. 2. was. T. whirTAKER, M. D. : - - - - Editor, No. 101 West Ninth Street, Cincinnati. W. W. SEELY, M. D., sº tº º ºs. º ºs TREASURER. No. 118 West Seventh Street, Cincinnati. printed and Published by THE CLINIC Publishing Company, -º- club fi Ares. ...s to 4 Copies to one address 6 46 . & 6 10.00 12 4; sº 18.00 C O N T E N T S. Page. on Io state MEDICAL society NUM IEER. THE PRESIDENT's ADDREss, delivered at Portsmouth, O., June 13, '72, by W. W. Dawson, M. D ...289 Transactions Finst Day—The Call to Order–Report of Executive Committee— The Reception Speech—Treasurer's Report—Twenty Minutes Papers—Announcement of Volunteers—A Bony (?) Heart. Afternoon Session.—New Members—Country Societies—Essays; Nervous Transmission, S. S. Scovill—Therapeutics of Electric- ity, Roberts Bartholow. Evening Session.—Essays; Elastic Tissue in Sputum, A. T. Keyt— Hernia Cerebri, P. S. Conner....... 294-296 is is e º ſº tº ºn SEGGND DAY. —The Status of Auxiliaries—Finance Report—Elec- tion of Officers—Essays; Medical Chemistry, J. B. Hough— Otology, W. W. Seely—Fracture Apparatus, Dr. Gay. Afternoon Session.—Refracture of Femur, W. W. Dawson—Multiple Tumors, A. Andrus—The Water Works, Manufactories and Banquet.........................................------------------------------------ 296–298 THIRD DAY. —New Instrument, T. A. Reamy—ESSAYS ; Amputa- tions, T. H. Kearney—Physiology in Practice, J. T. Whittaker Obituaries—The Presidents's Address—Standing Committees Fºº —Special Committees—Appointment of Delegates--The Round * T of Thanks in a Rising vote--The Fall of the Gavel *r-sº Medical College of Ohio. THEWhole Report of the Transactions, from beginning to end, is an earnest of the zeal and industry of the newly and meritedly elected Secretary, Dr. J. W. Had. lock, of this city. ...sºsºsºsºmº is The Proceedings of the Academy of Medicine are crowded over to the next number. Corrections.—In the last number of THE CLINIC Sec- ond original article, the word Cephalatomia appears in both title and text for Cephalaematoma, Wastemburg, as place of author's residence for Wurtemberg, and in .255-300 The Dental WW II. Tº Wiſſº, C0án & Co. t Hātītā Hālāſ; and lºadſ; if failſ, 92 FOURTH STREET, Opposite Post Office, CINTCINTINTATI, O-, - B& The Oldest Established Hat House on the Street. “Sã Fine Silk Hats, Standard Quality $6.00. ====--------------- Fº ºbesicºs ANº. NGRAVE op lºssºſ 82 WEST FOURTH Sºzº sºme sº * * J. TAFT, W. TAFT. Editor Dental Register J. & W. TAFT, TENTTIsTs 117 WEST FOURTH STREET, CINCININ ATI, O. Registers A Monthly Journal, CONTAINING 48 PAGES, the translation Exposure of the Cord for Exposure to the Cord, etc., Devoted to the Interests of the Dental Profession, ||||||||}|| MM|| ||M|| Fosºrr:R's 167 EAST 34TH-ST., NEW YORK, By Special Appointment Electrical Instrument Makers to the New York State Hospital for Nervous Diseases, MANUFACTURERS OF PORTABLE ELECTRO-magnetic machines, Portable Galvanic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, º 1870, and May 30th, 1871. These Instruments are the most Elegant, Powerful, Effica- cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery I'luid. - * |M|| |||||—|| || E*EERMANIENT BATTERIEs, For Hospitals and General Practitioners, IETIECTIER,CTDES. For Eye, Ear, Larynx, Nose, Uterus, Vagina, Bladder, Rec- tum, Feet, Phrenic and Sympathetic Nerves, Elec. trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. & –-O-C-O->- IEXTRA (!TS FROM TH E O PINIONS OF THE MOST Eſſ INIENT MEM B E HES OF TH F PROFESS / O N. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “Not HING CAN EXCEED THE EFFICIENCY AND CONVENIENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” We are authorized by Prof. Hammond to announce ein- phatically that the above extract, and the description of our Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, his reference only to the in- proved and re-modified Instruments made by our Company. MEREDITH CLYMER, M. D., Prof. of Diseases of the Neº- vous System and of the Mind, &c., &c.—“I consider their Galvanic and Induction Instruments as decidedly the very best for the therapeutic application of Electricity.” LEWIS BAUER, Prof. of Surgery, St. Louis:– In neat- ness, compactness and efficacy, they can not be excelled.” ALFRED C. G ARR. ATT, M. D., Boston :-"In cases of local palsy of muscles, it is the best, decidedly, of any and all I have seen.” Similar Testimonials have been received from JOHN J. CRANE, M. D., Vice-Pres. Med. Board, Bellevue Hospital; ALEX. B. MOTT, Prof. of Surgery; A. MUR RAY, M. D.; CHAs. E. BLUMENTHAL, M. D.; E. C. SEGUIN, M. D.; ALLEN MAYNARD, M. D., Cleveland, O.; Dr. C. WANN 1E, Waynesburg, Pa.; Dr. JOHN KING, Cincinnati; Dr. JAMES KELLY, Florence, 0.; Dr. JOHN BECKER, Brighton, Iowa; lyr. G. R. SKINNER, Polo, Ill.; Dr. E. R. MAYER, Wilkes- barre, Pa.; JOHN J. CALDWELL, M. D., Brooklyn, and many other prominent Physicians who are using our Appa- ratus in their daily practice, who thoroughly understand, both theoretically and practically, what is required in an Electrical Instrument for medical purposes. CALL OR SEND FOR CIRCULAR AND PRICE LIST. IE'_A_TIENT Are furnished to Officers and Soldiers on Government 8. CCOunt. I claim to have combined such improvements in ARTI- . FICIAL LIMBS as to make them superior to any others now in use. For the truth of this assertion, I would respectfully refer to my descriptive pamphlet which is sent free to the Medical profession, or to those wishing information con- cerning Artificial Limbs. . It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb–why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMES A. FOSTER, 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cincinnmati, Ohio, or 172 Jef- ferson Avenue, Detroit, Mich. SAML. P. THOMAS T.A. I. L. O.R., DEA LEF IN English, French and Scotch GOODs, 34 West Fourth Street, C.A.W.C.A.W.W.? TAZ. º f S. ºr ºw. ºf:= - - # ºf F- Fº:: | iſſilillº'ſ -º-Fºr- iº l ... " - | # !"; rººf. i. º | º | º #sº º | ſºlº ; ini | §: |||ſiſ it jilt i | § iſſiſſiſſiºni #lſº tºº - º =sº #######| =}|: | º E; ||| " . . . =#&#: ºf: §§ º º t | º É jºš. º- Q-ºy 2s * # § ºº§3 #$$. º ES$ SS º S$ : tº: - º º º º lºs wº, *. Fººtº -º-º-º: §. §g ºftº ####| || º 'º' i's ºf , º, |Rºſtillº: |- §§ | - T-E. J ÇS w §: * Scº S. S Sºº-Sºº - E-ET ~z. -** GooD s AMARITAN Hospita L. º-º- The GOOD SAMARITAN HOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner of sixth and Lock streets. It is handsomely furnished through” and is provided with all the necessary ap- pointments of a First-class Hospital. Porticoes, with commanding views, surround the whole house, and wide halls and abundant windows secure that full and free ventilation which is so essential to health and comfort. Service is furnished by the sistºrs of CHARITY, Under the Superintendence of the well-known SISTER ANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. The regular Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each Professor presiding over his own especial department. Patients may, however, select from the regular profession of the city any physician of their choice. The GOOD SAMARITAN HOSPITAL presents extra inducements to Invalids throughout the State as a safe and quiet asylum in any case of protracted illness, or in cases, more particularly, requiring Surgical Operation, where some stay is necessary in after treatment. Rooms vary in price, according to the character of appointments necessary and service required, ranging, in general terms, between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand of service. s - e tº- Address, - sISTER ANTHONY, Hospital of the Good Samaritan, Corner of Siacth and Lock Sts., Cincinnati. Ohio. WILSON BRO'S. S HIRTS Made to order of N. Y. M. Muslin and 2300 HEAVY Linen, per dozen - - - $26 00 Wamsutta Muslin and 2100 HEAVY Lin- en, per dozen - - - - - - - - 33.00 Wamsutta Muslin and 1900 Linen, per doz. 30.00 Lonsdale Muslin and 1700 Linen, per doz. 27.0) First three qualities have ALL LIN EN Cuffs and Neckbands. At above prices Cuffs are attached. Same quality of our own manufac- ture, ready-made, $3 per dozen less. Perfect satisfaction given or money cheerfully refunded. Also import and Manufacture Men’s Furnish- ing Goods. Pike's Opern-House, Fourth street, Cincinnati; 931 Wabash Avenue, and ss West Washington Street, Chicago. CAM'ſ A R.G.O MANUFACTURING COMPANY., MANUFA6TURERS AND IMPORTERS OF AND Window Shades, &? Wasz Kovazz Szwaaz, CINCINNXTI, O. B. B. BBENEMAN, Proprietor. WANTED–ACENTs. School Teachers, sºns AND OTHERS, Can find light and healthful employment for the Summer, by engaging in the sale of our valuable and very popular works. One lady teacher just commencing work for us, reports her net profits for last week at FoETY DoILARs—many others º equally well, Large commissions or liberal salary as preferred. For particulars, address NETTLETON & CO., 161 Elm Street, CINGINNAT1, CHIO: P. S.—We will make “special TERMs” to medical stu- dents, who are “working their own way through college.” BASCOM & CARPENTER, Stationers, Printers Blank Book Manufacturers, 136 VINE sº IIREET, s\SYNY, E. D. ALBRO & BRO. IMPontras AND MANur ACTURERs or FOREIGN and DOMESTIC WOODS In Veneers, Boards and Plank, frºm:-Mº','!-Bintuiti-kin"+, The only house in the western country that saws Spanish and Mexi: can Cedar for Cigar-Box Makers. Wºº. Ş..." wood direct, and can sell at prices to compete with any and everybody. Also º keep on hand a large stock of Poplar, White Walnut and Sycamore, for Cigar-Box Makers. once and warerooms, 136 and 138 West second street, * veneer Mill, 507, 509, 511, 513 & 515 W. Sixth St., CINCIMNAT1, -*s Wm. Wilson McGrew, wo. 27 hºsr Forrrrr Srwerr, Pike's opera House Building, Importer an d Dealer Diamond and Gold Jewelry, Watches for Ladies and Gentlemen, - Sterling Silver Tableware, Bronzes, Antique and Modern; Marble and Bronze Clocks Marble Statuary, J||NF||RTS, Carriage Manufacturer, NOS. 9 and 11 East Sixth Street, bet. Main & Sycamore. I MAKE NOTHING BUT Frºsz, czzss ºro waſ, Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of - * - LIGHT FAMILY CARRIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive variety of light elegant designs of different cost and finish. In vehicles especially adapted to - - PHYSECHANS” (SE, The annexed engravings Nos. 80, 82, 83 and 77 are popular selections from a number of styles I make for that purpose. - - The superiority of my light gentlemen’s buggies, road and trotting wagons, and racing work of every description, has long been acknowleged. Catalogues and price lists furnished on application. References to Dr. W. W. Dawson and all the leading Vºž Physicians in the city and heighborhood. º tº 2 ** gº tº T H E c T, INTI c. 289 Vol. 2.] s A T U R D A Y, J U N E 22, 1872. [No. 25. O HIO STATE MEDICAL SOCIETY N U M B E R . T H E PR E S I HD E N T 2 S A D D R E S S . BY W. W. D.Awson, M. D. Gº-mºssºms; mºsº Delivered before the Ohio State Medical Society June 13, 1872, **mº I propose to occupy this hour of your time with a few reflections upon the American Profession of to-day in com- parison to what it was twenty years ago, especially do I wish to contrast the teaching of the present with that of the past. Annual addresses, both state and national, are very much the same, so alike are they that the anti- quarian in looking over them will imagine them written by the same hand—dictated by the same brain. They all eulogize the honor, the dignity, the divinity-kinship of the Profession, but deplore at the same time the want of a high esprit du corps among its members, the fearful ignorance of medical students, and the great defects of medical education. To hear these railers you would think we are in a most deplorable condition. As this has been so general I think I will be excused from departing from a custom, so long and so faithfully if not profitably observed. It may profit us to look at physicians as they are, at medical students as we see them scattered over the land teaching country schools, as we find them grouped in medical colleges, and at the manner and success of medical teaching. Physicians form a large body of men, everywhere needed, everywhere present, in village, town and city. In character standing and influence they are in advance of any other class. Here and there an unworthy one is found but the great mass of them are men of temperance, integrity and high moral worth. They lead in works of benevolence, they respond to the call of humanity, they leap to the front when their country is in danger, they are identified with all efforts for the development of man's physical, moral and mental nature. Amongst themselves an esprit du corps characterizes their inter- course to which all other avocations and professions are Strangers, an esprit du corps, which, in its high tone, in its utility for protection and defense, in its ability to generate and maintain the kindliest relations between its members, is a marvel and a wonder to the non-pro- fessional. Who are the medical students found yearly in our Medical Colleges 2 They are young men gathered in large proportion from country school houses; many of them have graduated at Literary Colleges, most of them have fair educations, and in a very large number of cases, the education is the result of individual effort. It is from this class of self-developed young men that have come the physicians of to-day and from these physicians have arisen the men who give distinction to all departments of medicine. I say distinction for in many respects the Physicians of America are the peers of their fellows in any land. It will not be inferred that I underrate in the student the advantages of a thorough classical education. What I mean to say, is, that the profession is in better condi- tion than could be inferred from our annual orations on the defects of medical education, and what I hope to prove, is, that the real defects are gradually being reme- died, and that in time, and in a very short time too, medicine here will be as well taught and students will be of as high character as in any place on this globe. The marvel is that as much has been accomplished as has when we look at the history of the country and the early surroundings of most medical men. Sur- mounting all difficulties, overcoming all obstacles, by hard study making up for the deficiencies of thorough early training, the American Physician to-day stands abreast with the most distinguished, he brings his achieve- ments, his successes, his improvements, and his discov- eries and places them by the side of those gathered by the sons of more favored lands; these achievements, these discoveries, though probably not so numerous are equally positive, equally meritorious, are in fact great contributions to medical science. The reforms insisted upon by those who dwell upon the defects of our system of medical education consist of three recommendations, First, a higher standard for the Doctorate. Second, Longer sessions. Third, Graded studies. These are important suggestions, and fortu- nately for all parties the faculties of medical colleges have generally been alive to them, and as I have already said I hope to show that the radical defects of medical education are gradually but steadily being remedied, that sessions are gradually being lengthened, that lec- tures with this increase of session necessarily become graded and that the Doctorate yearly advances in worth, honor and dignity. This advance is as steady and faith- ful as it is desirable. * In proofof what I have said let us look at our Colleges, the time and manner of teaching, the qualifications of the young men who come to be taught and who in the end receive the degree. In most of our Colleges, in all I may say, the length of the session amounts to six months, formerly it was but four, then it was increased to five—now however, with a preliminary course in September which a large portion of the class attends, the session is in reality six months long. In less than half a decade the introductory in all colleges to the regular course will be delivered on the first Monday o 290 [JUNE 22, 1872. T THE TEE C T , IITNT I C. September and the valedictory on the corresponding day in March. The times demand the advances—the Colleges will undoubtedly make them. Already grad- ation in sludies has been adopted by one leading college and its example will be followed by others. The graded teaching as established at Harvard can be markedly improved upon, in many respects it is better than the old system of repetition, in some it is not so good, still it is a step in the advance and as far forward as the circumstances would justify. If you compare the manner of teaching now with what it was forty years ago or even twenty, the improvement will be as marked as they are hopefully inspiring. Take Anatomy, the basis of the whole structure— twenty years ago the Bones and Muscles occupied almost the whole course—these with a few and a very few lectures on the Viscera, Arteries and Nerves were all that were vouchsafed to the student. Now most schools have two professorships devoted to Anatomy, one to Anatomy proper the other to Surgical Anatomy, Wilsom inaugurated a new era in the teaching of this important branch, he brought form out of chaos, he showed how to teach Anatomy by teaching the relations of various parts to each other and faithfully and profitably have the Anatomists of the whole world followed his example. Now when a student leaves his College he knows more than than the origin and insertion of a muscle, more than that an artery is a branch of the aorta, more than that the stomach is in the abdomen. He is taught the situation and topography of the organs, the relation- ship of the various parts. He knows where to cut to divide a muscle, he knows where to seek for an artery. I do not overstate the fact when I say that the present intelligent and efficient manner of teaching anatomy in comparison to the past is as light to darkness. Think for a moment how Chemistry was taught twenty years ago and how it is taught to-day. Then the whole ante-holiday part of the session was devoted t) the fearful imponderables. In the last half of the term somewhat of Oxygen, Carbon, Nitrogen, Hydrogen, Alkalies, Acids, and Salts was discussed. Medical Chem- istry was not reached, the analysis of the secretions and excretions did not enter into the list of what was re- garded as essential in a medical man’s education. Now however, the graduate if he has been diligent, is master of these subjects, at least he has been so instructed that he has all the elements of success. He is drilled in urinalysis, he knows how to examine sputum, he can de- tect poisons and furnish the antidote for them in fact he is or has had the opportunity to be thoroughly competent to do all those things in Medical Chemistry required in the intelligent practice of his profession. In Materia Medica one of my Professors read from dingy, smoky manuscript that had seen service for twenty years. Once in a while, and a long while, a fresh scrap of white new paper could be seen interleaved with the yellow veterans. Now and then a specimen of plant or of earth, or of mineral was presented. The dryness, the dullness, the want of interest in that course is not easily forgotten. I do not select this course of lectures because it was an exception—it was a type. In Therapy the student was regaled with learned dis- quisitions on the fluids and solids, and the action of medicine upon them. If a man twenty years old in his profession will enter the room of the Professor of Materia Medica and Therapeutles of to-day he will be struck with the change. By throwing out the hundreds of useless agents and confining himself to the essentially valuable, by an intelligent discussion of their qualities, uses and indications, by a philosophical estimate of their actions, by an accurate knowledge of the parts of the body upon which they exert their influence, the Pro- fessor makes this department one of the most interesting and captivating to the student. Pharmacy is the legitimate offspring of an advancing, demanding spirit in the profession. Compare the elegant preparations of our Pharmaceutist with the villianous compounds which were prescribed a few years ago. Our patients, if not ourselves, have great cause for felicitation. Perhaps in no department has twenty years made such striking changes as in the teaching of Physiology. At that time in most of our schools Physiology Was appended to the chair of Anatomy and positively received no attention at all. In some schools a seventh chair was added called the Institutes of Medicine, this embraced or should have embraced Physiology and Pathology. One of the schools which I attended had a Professor of the Institutes, he was called a Giant in Physiology. This Giant spent a large portion of his time in teaching us Phrenology and Mesmerism; occasionally he relieved the tedium of these twin sciences by a lecture on vital forces. Another Professor in this department lectured from manuscript from which he seldom raised his eyes. These Giants had both been educated abroad and taught Physiology as they had learned it. Now the student is taken into the laboratory and taught the functions of the body by experiment—by vivisections. The gastric fistula by which digestion can be watched and estimated is now not an uncommon spectacle in our medical colleges. The functions of the nervous, lymphatic and glandular systems, the part which the great organs take in the animal economy are demonstrated with remarka- ble exactness. - When we reflect on the manner and successs of teaching the elementary branches, Anatomy, Chemistry, Physiol- ogy and Materia Medica of the present in comparison to what it was a quarter of a century ago we cannot but be struck with the hopeful contrast and we must admit that with all the defects of our system of medical teach- ing, that it is, all things considered, equal to any other department of science or letters in our new and develop- ing country. This brings us to a review of the present manner of teaching the practical branches, the application of the elements. And first I may say that almost everywhere JUNE 22, 1872.] in our country, Didactic and Clinical instruction go hand in hand. The importance, the absolute necessity of the union seems to be recognised by all. To Cincinnati belongs the honor of first uniting in this country a Col- lege and Hospital, Dr. Drake was the author of this system and from this initiative have grown results of the most lasting benefit. Colleges and Hospitals are now most intimately associated, not usually made one and the same institution as was projected by Dr. Drake, but so associated as to make the Clinics of the Hospital com- plementary to the Didactics of the College. But few schools are to be found without a College Dispensary at which students are trained in diagnosis and treatment. The chair of Gynaecology has been added in most of our colleges, thus rendering the instructions upon the diseases of women much more thorough and practical than was possible under the old regime. The diseases of the uterus, its degenerations, malignant and non- malignant, its changes of position and shape, its intimate relations with and modifications of its neighborhood furnish subjects for a full course of lectures, the vital importance of which need not here be discussed. In the Practice of Medicine the student is no longer sent away with theories and prescriptions, educated in the pathology of disease daily drilled in its diagnosis, he goes easily to the best remedies for its treatment. Physical Diagnosis is not old, but the last ten years has added very greatly to its exactness, to its reliability. The use and value of the Stethoscope is rendered familiar to the student because at the bed side he is taught the interpretation of the sounds transmitted through it. He knows when he leaves his Alma Mater what this means at the base and what that means at the apex. Ther- mometry now so important an adjuvant in revealing the vital condition is taught in the same practical manner. The Sphygmograph, a refinement in diagnosis is presented if not estimated. I think it would be diffi- cult to find a medical student of two years of age who could not tell you when and how to use the Induced Current and in what cases the Continuous Current is applicable. In the application, if not in the literature of this great remedy, we are certainly not behind the most advanced. - We have now the two special departments of Oph- thalmology and Otology, the importance of which is being so thoroughly realized, not alone for their practical results but as well for the opportunity afforded of pre- senting through them so many general points, and the student now has this additional advantage over the student of even ten years ago. When we come to review the present with the past of Surgery we may say that in America Surgery has always been well taught, and the world knows how successfully it has been practiced. The achievements of American Surgeons furnish among the highest adornments of our history. With what pride we constantly refer to the triumphs of such men as McDowell, Dudley, Mott, T EHI E3 CT, ITN. T. C. 291 Physic, Mussey and Blackman. Europe as well as America is filled with the renown of many of our lead- ing living surgeons. The "Europeans read their books, discuss their papers, use the instruments of their in- vention, admire and adopt many of their original oper- ations. The foreign surgeon when criticising American surgery is generally just—sometimes unjust—occa- sionally ungenerous. The following paragraph from the recent valuable work on the Science and Practice of Surgery by Frederick James Gant belongs to the latter class; in discussing the the history of Ovariotomy he says: “Extirpation of ovarian tumors, cystic or solid, is an operation of comparatively recent date, suggested by Dr. Wm. Hunter, advocated by John Bell and first practiced by Dr. McDowell in 1809, the latter an Amer- ican pupil of John Bell. Ovariotomy is, therefore, un- questionably, an operation of British origin, and it is to the labors of British surgeons that its subsequent progress is chiefly due.” Mr. Gant is somewhat more accurate than his neighbor Mr. Butcher, of Dublin, who in a late article attributes to Mr. Lizars, of Scotland, the credit of having first performed the operation. Mr. Lizars cut into an obese woman in 1823 but found no ovarian dis- ease, while Ephraigm McDowell, of Danville, Ky., per- formed Ovariotomy successfully in 1809. His patient lived for years after. How absurd and unjust in Mr. Gant to claim the honor of this great operation for British surgery when we remember that Great Britain never had a completed case until 1840, nor a successful one until 1842, and especially as up to that time the operation had been performed in America more than forty times. This pioneer operation of Ephraigm McDowell may justly be regarded as the most daring feat in the history of surgery. Imagine his surroundings, in the “back woods” of Kentucky, in 1809, it was indeed a back woods full yet of Indians and wild animals, there, in that almost unbroken wilderness, with no counsel, no support, he not only conceived, but successfully performed that wonder- ful operation. Realize if you can the intrepid heart and force of brain of that early American Surgeon as he made the first incision in that case—as he progressed in that operation—an operation hardly thought of, occasionally suggested, but never really advised. Picture if it be possible the surroundings of that man and then you may have some idea of his great knowledge, his wonderful nerve and his unequaled self-reliance. Benjamin Dudly was as successful in Lithotomy as is Sir Henry Thompson to-day with his selected cases of Lithority. - American surgeons have taught the world that Vesico- vaginal Fistula is almost always remediable, they did not originate the operation, but they have shown how it can be successfully performed, and that too under the most unpromising complications. You will realize the truth of what Isay when I tell you that a colleague of mine during a recent visit to Europe witnessed the treatment of a case of Vesico-vaginal Fistula in a London hospital 292 [JUNE 22, 1872. TIEEI IEH C T , I INTI C. by the daily application of Nitrate of Silver. The tide of surgical students might with profit be reversed. Such Hospital Surgeons could learn something, could indeed learn much, by visiting this country. The relief of one case of Vesico-vaginal Fistula is worth a whole lifetime of labor, it is a diadem in the crown of a surgeon and I am proud to say that most American Surgeons have a number of these jewels. Pulleys and Adjusters have given away to manipulation in the reduction of dislocations, the key to this was furnished a few years ago by a New York surgeon. What a revolution in the treatment of fractures we have made by elastic extension and sand bags. The surgeons of all countries read Dr. Hamilton's book on “Fractures and Dislocations,” they read it because it is the best book in any language. For the general practi- tioner what book can be compared to Gross' System of Surgery. A new era has dawned in the treatment of joint dis- eases, especially disease of the hip, and it is most doubt- less true that the most valuable contributions are due to the learning and skill of New York surgeons. Where except in this country do you find Morbus Coxarius so treated as to secure complete use of the limb and joint? I might extend this list of American contributions to surgery very greatly and with instances equally striking as those already presented, for it cannot be denied that in surgery we have given as much as we have received. And here I may make the pertinent inquiry; if our system of medical education be so defective why this great excellence in the men who have been educated by it? It is unusual to see such fruit from a tree that is all unsound. The annual examination for the degree of Doctor of Medicine in most of our colleges is now made by written questions and written answers, thus a better knowledge of the student’s ability is obtained than by a thesis written in his own room with books and his room mate or some medical friend to draught upon. The plan is essentially the same as that adopted in Great Britain in the examination for Degrees, License, for Hospital Interne and entrance into the Army, Navy or India service. And now let us look for a moment at the questions pre- sented in this country and in Europe. For comparison I take those given by the staff of the Cincinnati Hospital at the last examination for Internes, and those adopted by the faculty of one of our colleges at a recent exami- nation for the Degree. I use the questions of these two institutions because I happen to be in possession of them —I have no doubt however but that they are fair types of those used in most of our Colleges and hospitals. Questions Submitted to the Candidates for the Position of Interne in Cincin- nati Hospital, 1872. O}}STETRICS. 1. Name the positive signs of pregnancy. . . . 2. What presentations are unnatural requiring interference 2 . 3. Where the face presents what relation must its long diameter sustain to the inferior strait for safe delivery 7 4. How is assistance to be rendered when the presentation is dis- tending the perimeum ? - 5. Where and how soon should the funis be tied after the expulsion of the foetus 2 6. What are the signs of placenta previa? 7. Name the displacements of the uterus. 8. Name the symptoms of prolapsus uteri. 9. How would you treat dysmemorrhoea 7 10. How would you treat amenorrhoea 7 OPHTHALMOLOGY. 1. How would you treat foreign bodies lodged in the cornea 7 2. Give a differential diagnosis of simple conjunctivitis and iritis. 3. What is accommodation and how is it effected ? 4. What is the difference between presbyopia and hypermetropia 2 5. What nerves supply the muscles of the eyelids and eyeball? 6. Give the diagnosis, course and treatment of ulceration of the CO1 nea. 7. Give the diagnosis and sym É. of cataract. 8. Describe the treatment of diphtheritic conjunctivitis in its three StageS. 9. Give the diagnosis and treatment of acute granulations. 10. Ilescribe the different methods of operating for entropion of the lids. SURGERY. 1. In strangulated hernia what difference in the dissection of the division of the strictures is necessary to avoid the internal epigastric artery in cases where that stricture is at the internal ring and in others where the stricture is at the external ring 2 What is the condition of the skin in eczema, the pathological products of that disease, and its chief symptoms ? Name the common forms of gangrene. What effects may be obtained from poultices and mention some of the conditions indicating their use ? wººion of the alimentary canal is apt to occur in cases of urn ? . At what point is the clavicle most frequently fractured, state the symptoms indicating such injury and what are the chief indi- Cations in the treatment 2 At what portion of the urethra is stricture most frequent 2 State the chief characteristics of the initial lesion or sore of syphilis and those of the soft sore or chancroid respectively. What is Hunter's method of ligature of arteries for aneurism and the principle on which it is based ? Mention different means for the arrest of hemorrhage. & : : PRACTICE OF MEDICINE. What is your method of taking the clinical history of a patient 2 How do you distinguish between pleuritic effusion and consolid- ation of the lung from pneumonia 2 Give the diagnosis and treatment of pericarditis- What pathological conditions may produce dropsy % º How would you proceed to investigate a specimen of urine 2' On what different pathological conditions may Bright's disease depend ? What conditions may produce hemiphlegia 2 What is the difference between dysentery and diarrhoea 7 What causes may produce obstimate constipation ? Give the symptoms and treatment of delirium tremens. 1 PATHOLOGY. Origin of pus corpuscles. Pathology of thrombosis. Pathology of embolism. Minute anatomy of healing by granulations. Pathology of miliary tubercle. Pathological characters of a malignant as distinguished from a benignant tumor. - - Morbid anatomy and pathology of cerebral hemorrhage. Pathology of cardiac hypertrophy. Pathology of aneurism. Morbid products in pleurisy and the manner in which, they are disposed of. - I The following Questions, ten in each Department, were submitted to the ; Graduating Class of 1872 in the Medical College of Ohio. wº- ANATOMY. Give a general description of the skeleton. Describe the os femoris. What are the essential components of an entirely movable Joint 7 Describe the elbow joint. Describe the heart. Give its position. Describe the larynx. Describe the trachea, bronchi and bronchia. - - What are the enveloping membranes of the cerebro-spinal axis 2 *A JUNE 22, 1872.] T IEEE EIH C T , T TNT I. C. } 293 10. What are the great divisions of the encephalic mass and their relation ? suPGICAL ANATOMY. 1. What is the best place for ligating the common carotid artery, and what are its relations at that part 2 2. Popliteral artery, where found and relations 7 3. What are the anatomical objections to ligating the first and sec- ond portions of the subclavian artery 7 4. Scarpa's triangle, boundaries and important parts contained ? 5. By what muscles is the inner border of the foot elevated ? Fº l, upper third of radius, in what position best treated, and why What are the parts divided in the lateral operation of lithotomy 7 8. Surgical anatomy of the shoulder joint. 9 Surgical anatomy of the elbow joint. 0. Surgical anatomy of the hip joint. PHYSIOLOGY. The digestive juice with the widest range of action, and its chief ingredients 2 * Trace fat through the system. The cause or causes of circulation in the veins ? Capillary circulation, continuous or intermittant, in either case why? Chief use of the red blood corpuscles 2 Uses of Sweat 2 i Th: Hºnºliate and subsequent effects of wounding the cere- €ll lirrh The diurnal range of temperature and the variations compatible with health ? - The necessary quantity of air in cubic feet for 24 hours ? Describe a spermatozoid. I CHEMISTRY. Enumerate the general properties of acids and bases. Give the composition, formula, and mode of preparation of hy- drochloric acid. Describe the tests for arsenic. What is the antidote to arsenic and how prepared 7 Describe normal urine. - How is urea obtained from urine 7 How are chlorine, sulphuric acid, potassium and sodium detec- ted in urine 2 Describe the tests for sugar in urine. How would you determine whether a deposit consists of urates, phosphates, oxalate of lime or uric acid 7 How would you discover blood in urine? : i 8. Mention the forms of dysmemorrhoea and differential diagnosis. 9. What are the conditions capable of producing amenorrhoea 7 What are the disease which may produce pelvic abscess 2 OBSTETRics. Give positive signs and duration of pregnancy. Give diameter of pelvis at brim and outlet. Give diameters of foetal head. - Describe the anterior and posterior lateral inclined plains, and their relations to the mechanism of labor. Give the four cranial presentations, with the diagnosis of the first. Management of natural labor. Under what circumstance would you turn, and how 2 Cause, symptoms and treatment of unavoidable hemorrhage. Cause and treatment of post-partum hemorrhage 2 Symptoms and treatment of puerperal convulsions f . I OPHTHALMOLOGY. Name the bones that form the orbit. Name the muscles found in the orbits giving the nerves that innervate them. Giving a case of internal squint, how could you tell whether it was paralytic or not? Give the condition of the lids in ptosis and facial paralysis, with the muscles and nerves involved. Give the structure of the eye from before backwards. Give the points of differential diagnosis in the various con- junctival inflammations. Differential diagnosis of iridal and corneal inflammation with the general plan of treatment in the latter and the particular of the former ? - Of what does the lachrymal apparatus consist and what may interfere with the carrying off of the tears? 9. What is a cataract, and what is its treatment 7 Wºre the two methods of examining the eye with artificial 19. . 8. MATERIA MEDICA: 1. Why is cod liver oil the best form in which to administer a fat 2. Describe the effects of arsenic on the primary assimilation. 3. Name the preparations of arsenic and the dose of each. 4. Give the composition of opium. What is the treatment of opium narcosis 7 What practical test for the purity of chloroform may be made at the bedside 2 •. In danger of chloroform harcosis what methods of resuscitation are proper ? What is the distinction between galvanism and Faradism 2 To what class of cases are these two forms of electricity especially applicable 7 & * Write a prescription for a purgative pill ? ººe gº 10. * Questions at the Examination of Candidates for the English Indian Medical Service. I 0. SURGERY. What are the various processes by which fractured bones unite 7 What are the means you would use for strangulated hernia be- fore resorting to an operation, and, failing in these, what are the operations recommended, and the advantages of each 3 . In what injuries of the ankle joint is deformity inevitable 7 . What are the stages of hip-joint disease, and the treatment of tº each stage 2 & #. 3 4 5. How wouiſ you treat wounds of the stomach 7 6. What are the indications for amputation ? 7. Describe the various methods of Acupressure. 8. Differentiate between intra and extra-capsular fracture of the neck of the femur. 9. Differentiate between abcess, encephaloid, aneurism, hermia and adenoma 2 Name the principal disease which affect bones. PRACTICE. 1. sº the prominent facts in the clinical history of malarial OVerş. 2. What is the cause, course and termination of hepatic abcess 7 3. What are the symptoms and dangers of desquamative nephritis? 4. Diagnosis between real and feigned epilepsy 7 5. How treat habitual constipation ? 6. What are the physical signs of pericarditis 2 7. Diagnosis between peritonitis and enteritis. 8. How distinguish fixed neuralgia from inflammatory palm ? 9. Give the dry and moist rules; what do they indicate 7 10. How would you treat cardiac hypertrophy Ž GYNAECOLOGY. 1- Describe the uterus, location, size, weight, division, structures. 2. In what particular does the neek of the wound differ from the body of the wound 7 3. Describe ovulation and menstruation. * 4. . What §. would enable you (if possible) to determine the difference between specific and non-specific vagunitis 5. Mention the most common diseases of the uterus in the order of their frequency. 0. Nºme the various substances that may be expelled from the female pelvic organs. 7. Give the probable and positive evidences of the existence of uterine cancer. ANATOMY AND PHYSIOLOGY: 1. Give a genearl description of the spinal column, arid of the course of its ossification. 2. Describe the mode of development of a vertebra in general, iudicating the exceptionable cases (exclusive of the sacrum and coccyx) 2 3. Enumerate the various muscles and describe their respective actions, by which the deformity witnessed in the following fractures is robably caused : 1st, Fracture of the neck of the femur ; 2nd, ractuae of the lower end of the femur immediately above the condyles; 3rd, Fracture of the lower end of the radius (Collis's fracture.) 4. Describe the arch of the aorta, the relations of its various posi- tions and the dissection necessary to examine it, mention also the principle variations in the positions of its branches. 5. Describe the parts contained in the space bounded in front by the osterior border of the sterno mastoid, behind by the anterior i. of the trapezius, ahd below by the claviclé. 6. Gaye a general account of the lymphatic and lacteal system, ºng the minute structure of the lymphatic vessels and &ll C. S. 7. Dº the physiological effects of the division of the vagi Ile I'VeS. 8. Mention the parts in other vertebrate animals which are homolo- gous with the human händ, or parts of it. SURGERY. 1. Describe the states tiamed respectively “shock” and “reaction,” as seen in such agaše as that of a crushed limb 2 Enumerate the chief varieties of inflammation of the testicle, and state the distinctive characters of each: Give an account of secondary hemorrhages such as may occur after amputations, and of the best modes of treating them, 3: 294 [JUNE 22, 1872. TIH. H. C.T.I.N.I.C. 4. Whnt ill consequences may follow dissecting wounds, and what are the best means of treatinent, preventive and curative 7 5. What are the chief means by which in the treatment of hernia, the taxis may be assisted, and in what conditions is each of them most useſul ? º 6. Describe the process of repair of a tendon after subcutaneous Section. 4- - Lescribe the several diseases of the eye that are connected with syphilis and gonorrhoea. 8. A man 53 years old while under treatment for slight stricture of the uretha, was exposed to cold damp weather, the next day had a severe rigor followed by heat and sweating, and Com- pletely lost the power of passing urine. On each of the next two days he had similar rigors, and on the third day he was not only still unable to pass urine, but had constant straining and extreme pain in his endeavors to do so. During three days more these symptoms continued with rigors, and these were gradually added to them, pain in the perineum and about the arms, tenderness on deep pressure in front of the anus and º, forcing pain referred to the lower part of the rectum. The bladder was regularly emptied with a catheter and was not painful on pressure, the urine was generally healthy. Diagnose this case and give treatment. Questions submitted to Candidates at the Primary Examination jor the Diploma of Membership of the Royal College of Surgeons, London. * Describe the boundaries of the posterior mediastinum and its contents in their relative position. Describe the structure of veins and the forces by which the venous circulation is carried on. Describe the ligaments of the hip joint, and mention the mus- cles in contact with its capsule. - Give an account of any ºriº with which you are ac- quainted, illustrating the influence of the pneumogastric nerve upon the action of the heart. Lescribe the ligaments connecting with the clavicle, and men- tion the parts that pass beneath it in their relative positions. 6. Describe the ciliaris muscle and its action. : 5 º SURGERY AND PRACTICE OF MEDICINE. How would you distinguish, surgically, chronic induration of the breast from scirrhus. What are the microscopic ap- pearances by which each is characterised ? 2. Describe the operation of excision of the elbow joint, and state under what circumstances it may be required. 3. What treatment would be required in a case of incised wound of the cornea, with protrusion of the iris. Mention the conse- quences which may ensue, and the proper mode of dealing with them. What are the causes which may impede the union of a fracture of a long bone; describe the mode of treatment which might be resorted to in order to promote the union of an united fracture ? 5. Describe the deligation of the right carotid artery in the first part of its course, giving the exact relations of the parts con- cerned in the operation. 6. Mention the different forms of naevus and appropriate modes of treatment. 7. Describe a case of Fº of the facial nerve, and mention the causes upon which it may depend, and the treatment you would adopt for its relief. 8. What are the circumstances which would induce you to have a recourse to thoracentesis in a case of effusion in the pleural sac, state how you would perform the operation and the changes that would follow it. 9. Write perscriptions in Latin in full, and directions in English, for a diuretic mixture and a purgative powder and give composition and doses of the following preparations; Pulvis Julapae Composita; mix- tura ferri composita; tinctura Camphora Composita. Liquor Morphia Hydrochlor. In the exhibition of these questions I hope I have not been tedious, I have ventured upon them for herein lies the argument, for we see by them that our Schools and Hospitals take as wide a range and ask as difficult questions as is done by examining bodies elsewhere. These questions show the extent of teaching and it will not be contended that a young man who answers seventy percent of them is not well educated. The lesson of this whole matter is that the Professon in this country is not in as bad condition as would be inferred from these annual howlers. In Medical Literature America certainly stands well, our books are read in all countries. In Surgery, Med- icine, Therapeutics, Physiology, Chemistry, Obstetrics, Gynecology our authors have won well merited fame. Our Medical Journals are yearly by their merits chal- lenging recognition. It is said that they contain much trash, this is true but it is equally true of foreign period- icals. It is not all wheat within the lids of any medical work, unadulterated wisdom is not found in medical journals, I do say however that brains predominate in our medical literature. - Thus by the steady advance in the manner and efficacy of teaching, by the yearly improvement in the preliminary education of students, by the increase in the length of the lecture term and what is still better than all an enthusiastic love of the profession, our Medical Colleges will annually send out a class of young men from whom may be expected the best of things, many of them will take high rank and distinguish themselves in fields where distinction is the result of true Worth. ..—sº-º-º- on 1 o sºr a re n e orca 1 so c 1 Etx. Twenty-seveNTH ANNUAL MEETING. PoRTSMOUTH, JUNE 11th, 12th, AND 13th, 1872. FIRST DAY. Morning Session. The Society met in Wilhelm's Opera House at 10 o'clock and was called to order by the President, Dr. W. W. Dawson, of Cincinnati. - Rev. Dr. Burr of the Episcopal Church opened the , meeting with prayer. Vice-Presidents Drs. C. P. Landon, E. Sinnett and J. W. Russell took seats on the stand. Secretary Dr. J. W. Hadlock was present. Ex-President Dr. Hempstead was escorted to the stand and introduced as one of the earliest Presidents of the Society. Also Ex-Presidents Drs. E. B. Stevens, Kincaid, and Dunlap, took seats on the stand. Dr. Jones, of Portsmouth, moved that the reading of the minutes of last year's meeting be dispensed with. Carried. REPORTS OF COMMITTEES. Dr. Pixly made the report of the Executive Com- mittee as follows: Your Executive Committee wish to report that they have secured the use of Wilhelm's Opera House for the Society. JUNE 22, 1872.] The Committee suggest that the meetings be held at 9 o'clock A. M., and at 2 o’clock P. M. On Wednes- day at 9 o'clock A. M., Election of Officers; at 2 o’clock P. M., President's address; at 4 o’clock P. M., Display of Water Works; at 9 o'clock P. M., The Society is in- vited to a Banquet given by the citizens, at the Opera House. Thursday at 11 o'clock, invitation to visit Gaylord & Co.'s Rolling Mills, and Burgess's Steel and Iron Works. - - Arrangements for the reduction of fare to members and their families have been made with the following railroads, viz., Marietta and Cincinnati; Cincinnati, Hamilton and Dayton; Cincinnati, Sandusky and Cleveland; Columbus and Hocking Valley and the Baltimore and Ohio. - - - - A. B. Jones, M. D., Chairman. C. M. Finch, M. D. M. S. Pixley, M. D. - L. Schwab, M. D. Dr. A. B. Jones of Porttmouth welcomed the Society in the following neat address:— M.R. PRIESIDENT: - - . . . Gentlemen of the Ohio State Medical Society and others: The Profession of Portsmouth has made it my pleasing duty, to formally extend to you, their kindliest greetings. This I do with mingled emotions of pride and pleasure—of pride when I reflect that this society has numbered among its members, physicians, Surgeons and specialists, peers, to any the world has ever produced; and upon whose worthy shoulders now rest the mantels of the great departed. Of pleasure in giving my right hand with the hearty God bless you to our home—to our quiet little city. : We all, both in and out of the profession, fully appre- ciate the very distinguished honor you have conferred upon us by bringing here the ripe sheaves as the fruit of your past year's sowing, working and reaping to be garnered amongst us. Then let us rejoice and make merry together; and when the day's work is done, remember the last load of corn for the year has been brought home: and, when you retire to rest to-night have no nervous or fitful dreams, for fear the loud rat- tling of the door bell may summons you in the still watches of the night, to again go over and over your weary rounds with your still more weary limbs. We hail your advent in our city, as the dawning of a new era in our profession here. So many great and good men whose lives and energies have been devoted to the relief and comfort of others, cannot come and go without leaving an impress behind them of good. I trust our meeting together on this occasion will not only be a pleasurable, but also a profitable one; and that each one of you may return to your respective fields of labor and usefulness, refreshed in body, strengthened in mind and cheered with hope—hope of the hopeful, whose reward consists in the self-gratulatory feelings of having done ones duty, by lightening the burden of life which man inherited when he fell, and brought TIEEI IEH C T , T INT I C - | has been reaping. 295 “death into the world and with it all our woes Yours can never be the reward of gold. Schiller tells us that at the sharing of the earth, the husbandman, the merchant, the lawyer, the monarch, all got their share; and, even the parson came in for his wine: while the poet who had been holding up nature's mirror to each fond professor got nothing: so in utter dismay he appealed to the gods. Jove asked him where he had been when the earth was divided. I was, said the poet, with thee and so enraptured was I with thy world as to love every portion of it. “Alas, alas, said the god, earth is given I Field, forest, and market, and all! What say you to quarters in heaven? We'll admit you whenever you call.” Now gentlemen I have no doubt but the gods have reserved a place for the doctors up there with them; and if so I know you will be thankful. Another year since last we met has closed its book and stamped its record forever; time too, with his sickle He spared not even the healer, and among them, has he taken into the dark beyond, the immortal Blackman, whose name is now never spoken either by friend or foe, without profound admiration. Many others of us have gone over into the unknown world to shed their lustre there; and me thinks, that as one by one of our social few goes over, it will lessen the darkness of the gloom; and soon, very soon, our Society will number more there than here. Then let us forget not, while we are trying to cool the fevered brow, or relieve the burning thirst, to drink deep, ourselves, of the pure waters of Siloam. Report of executive committee was adopted. Dr. E. Sinnet with appropriate remarks presented to the Society a beautiful silver mounted gavel. The President returned thanks for himself and all future Presidents of the society, for this timely, useful and handsome present. - REPORTS OF COMMITTEES. Reports of committees being called for a number were announced ready to report. REPORT OF TREASURER. The report of the Treasurershowed a balance of $12,81 cents in the treasure. Report received and referred to committee on finance. Dr. W. J. Conklin, of Dayton, was, at this juncture, appointed Secretary pro tem. MISCELLANEOUs BUSINESS. Dr. Bartholow moved that all papers be read by abstract not to exceed twenty minutes in reading. After some discussion the motion prevailed—when Dr. J. B. Thompson moved a reconsideration of the matter for the purpose of so modifying Dr. Bartholow's motion that the rule shall not apply to the reading of papers this year. A reconsideration was had and Dr. Thompson's modification prevailed. VOLUNTEER PAPERS, Volunteer papers being called for Dr. Bartholow 296 [JUNE 22, 1872. T IEEE THE cIIINI c. announced a paper on “Aneurisms of the Basilar Artery.” Dr. E. Sinnet announced a volunteer report of “Two cases of Monstrosity.” Dr. Gay presented a pathological specimen with history of case, of heart incased in bony formation. Remarks were made on the case by Drs. W. W. Seely and J. T. Whittaker. In answer to Dr. Bartholow Dr. Gay stated that a specimen of the bony case had been subjected to microscopical examination and found to be true bone, The following named gentlemen were favorably re- ported on for membership and unanimously elected. Drs. Robert Wesley, Athens, Ohio; D. T. Daris, Day. ton, Ohio; W. V. Peck, New Richmond, Ohio; Thomas G. Vaughters, Portsmouth, Ohio; David Coleman, West Union, Adams Co., Ohio; J. L. Wylie, Ripley, Ohio. The President announced the name of members of committee on finance as follows: Drs. Jones, (of West Liberty,) E. B. Stevens, D. D. Bramble, Finch, and Jenney. Drs. S. S. Scovill and Bartholow were announced to read papers during the afternoon session. The Society then took a recess until 2 o’clock P. M. Afternoon Session The Society met at 2 P. M., as per adjournment, and was promptly called to order by the President. Dr. Pixly, from Executive Committee, reported that soda water would be served the members of the Society, free of charge, at the various drug stores of the city, The following names were presented for membership and unanimously elected: Drs. A. Andrus, D. W. Coffee, both of Westerville, Ohio; B. F. Kitchen, Clay P. O., Jackson Co., O. A question here arose as to the status of members of this Society who came as delegates from auxiliary societies. Referred to Committee on Medical Societies. Dr. L. A. Grimes, of Concord, Ky., and Dr. C. Honacker, of Vanceburg, Ky., were here introduced and invited to take seats with the Society. The Finance Committee here made a partial report, Report received. Dr. Gray moved that the salary of the Treasurer here- after be $50 instead of $150. Carried. Dr. Kincaid moved that the annual dues be fixed at $2 instead of $3, as recommended by the Committee. Carried. Report was then adopted. Dr. J. B. Thompson here offered his resignation as Treasurer. Resignation accepted and Dr. Gray elected Treasurer of the Society. The President announced the Committee on Medical Societies as follows: Drs. A. C. Miller, Miles, Wylie, Hough and Hyatt. The Committee on Admissions reported the following named gentlemen for membership, who were unanimously elected: Drs. James L. Taylor, Wheelers- burg, O., J. A. Warren, Wheelersburg, O., W. A. Frizzell, Buena Vista, O. Dr. J. B. Thompson resigned his place as Librarian, and Dr. Gray, treasurer elect, resigned his place on the committee on admissions. - Dr. E. Sinnett moved that a vote of thanks be tendered Dr. Thompson for his long and useful services as Treasurer of the Society. Motion heartily responded to. REPORTS OF SPECIAL COMMITTEES. Dr. S. S. Scovill, of Lebanon, having previously been announced, read a report on “Nervous Transmission.” The report was elaborate, read with energy and listened to with marked attention by the members of the Society. Remarks on the report by Drs. Whittaker, Hough and Scovill; after which the report was received and re- ferred to Committee on Publication. *. Dr. R. Bartholow, read a report entitled “Some Points in the Therapeutics of Elec- tricity, illustrated by cases.” The report was well received and listened to attentively by the members. Remarks on the report by Dr. Reed who reported cases confirming the position taken by the author of the re- port on the value of electricity as a therapeutical agent. Drs. Hough, Whittaker, Miller and Scovill also made remarks touching the report. Report received and re- ferred to Publication Committee. Dr. Landon moved that the Society take a recess until half-past Seven o’clock in the evening. Carried. Evening Session. Society called to order by Vice-President Dr. C. P. Landon. REPORTS OF SPECIAL COMMITTEES CONTINUED. Dr. A. T. Keyt read a report on the “Semiological Value of Yellow Elastic Tissue in Sputum.” The report, although lengthy, and occupied the major part of the evening in its reading, was listened to throughout with marked and critical attention by all present. Report received and discussed by Drs. Barth- olow, Whittaker : whereupon it was referred to Com- mittee on Publication, Dr. P. S. Conner read a report on “Hermia Cerebrº.” Referred to committee on publication. The society then adjourned to meet Wednesday morning at 9 o'clock S E C O N D D A Y. Morning Session. The Society met at 9 o'clock, and was called to order by the President, Dr. Dawson. Prayer was offered by the Rev. Mr. Manly, of the Biglow M. E. Church. Minutes of yesterday's proceedings were read by the Secretary and approved. JUNE 22, 1872.] T H H C T.I.N.I. c. 297 REPORTS OF COMMITTEES. The Committee on Medical Societies made their re- port as follows: Mr. President : º Your Committee on Medical Societies having had under consideration the matter which to them was re- ferred beg leave to report the following as the result of their deliberation, viz: 1st. That in accordance with article 7th, of the by-laws of the Ohio State Medical Society it is the opinion of your committee that societies represented by the delegates are subjects for consideration in committee and not the delegate. 2nd. That in accordance with the foregoing your com- mittee have examined the credentials of S. S. Scovill, M. D., and J. B. Hough, M. D., regularly appointed delegates from Lebanon Medical Society, and of C. R. Reed, M. D., representing the Meigs County Medical Society, and of H. C. Watterman, M. D., of Middleport, representing the Meigs and Mason Academy of Medicine; Drs. A. Blymer and A. Andrus, Delaware County Medical Society; Dr. J. W. Coble, Central Ohio Medical Society; Drs. N. S. Hill, W. V. Peck, W. L. Anderson, A. W. Ashburn, R. B. Davy, Eugene Moore, R. C. Moore, Clermont County Medical Society; Drs. D. B. Cotton, W. J. McDowell, Scioto County Medical Society; and find that said societies are in good and regular standing as Auxilaries of this society, and that said delegates by virtue of their appointment are entitled to a part in the deliberations of this Society. 3rd. That your committee have examined the con- stitution and by-laws of the “Delaware Medical Insti- tute,” and find that they strictly conform to the require- ments and usages of this Society, and recommend it be made auxiliary to the Ohio State Medical Society. 4th. Whereas, there does not appear to be any estab- lished usage in the transactions of this Society, regu- lating and governing delegates from Societies made auxiliary to the Ohio State Medical Society, and, Whereas, to avoid controversies hereafter, and for the more uniform government of said delegates, be it there- fore Resolved, That delegates representing Auxiliary Socie- ties in good standing, shall, upon satisfactory evidence, be entitled to take part in the deliberations of said State Society during the session for which they were elected, but shall not be entitled to membership or other con- siderations unless they become a regular member of this Society, and pay the usual initiation fee. Respectfully submitted; A. C. Miller, J. L. Wylie, A. J. Miles, E. H. Hyatt, J. B. Hough, Committee. The Committee on Finance after having examined the books and accounts of the Treasurer made their Supplemental report as follows: Mr. President; Your Committee on Finance have examined the book accounts and vouchers of the Treasurer, and find them all correct. We recommend the payment to the estate of Dr. Hall (late deceased) the balance of his salary for 1871, of $25; also account rendered by Dr. Hall (for postage) $270. {} Dr. Hadlock, as Secretary, presented a bill of items $25.20, which was recommended to be paid. A bill for salary of Dr. Hadlock, as Secretary, for $50, we do not feel authorized to allow ; but we recommend the payment to Dr. Hadlock, of whatever expenses he may have incurred additional to the above, in performing the duties of Dr. Hall during his dis- abilities. Respectfully submitted; L. M. Jones, C. M. Finch, E. Jennings, Edward B. Stevens, D. D. Bramble. Committee. 4. During the morning Session the executive committee presented the following communication. PortSMOUTH, O., June 12, 1872. Drs. Pixley, McDowell and Bing, Executive Com- mittee. Gentlemen :—The undersigned committee of the Board of Trade of our city, in behalf of the body we herein represent and of the citizens generally, hereby extend to the members of the Ohio State Medical Asso- ciation, now here assembled in convention, a cordial invitation to accept an entertainment to be given them by said Board and the citizens at Wilhelm's Opera House this evening, the 12th inst., at 9 o'clock. Very Respectfully, Thos. Dugan, R. Bell, Jas. Rum- sey, George Davy, P. Tainey. Committee. * On motion the above invitation was accepted. The following named gentlemen were presented for membership and unanimously elected ; Drs. E. D. S. Morgan, Berlin, Ohio; D. C. Wilson, Ironton, Ohio; Emil Arnold, Ironton, Ohio; C. M. Wilson, Miami Springs, Ohio; H. K. Steel, Denver, Colarado, Honorary member; P. Beeman, Iola, Allen Co., Kansas, Honorary member. Dr. J. B. Thompson made a statement that Dr. R. J. McClain owes the Society near $15.00 and the Doctor having been absent for Some years, int he army, he now proposes to pay the Society two-thirds the amount and be reinstated to good standing in the society. Referred to committee on finance. ELECTION OF OFFICERs. The election of officers for the ensuing year resulted as follows:—President Dr. A. B. Jones, of Portsmouth, Ohio; Vice Presidents Drs. A. Blymer, Delaware, Ohio; J. D. Cotton, Marietta, Ohio; W. J. Anderson, Newtonville, Ohio; J. B. Hough, Ridgeville, Ohio. Treasurer and Librarian, S. S. Gray, M. D. Piqua, Miami Co., O. Secretaries, J. W. Hadlock, M. D. Cincinnati, Ohio; W. J. Conklin, M. D. Dayton, Ohio. Committee on Admission, Dr. M. Cassat, Dr. N. S. Hill, Dr. S. S. Scoville, Dr. T. W. Gordon, Dr. E. H. Hyatt, - 598 [JUNE 22, 1872, TIEI IE C T , I INT I. C. REPORTS OF SPECIAL COMMITTEES CONTINUED. Dr J. B. Hough from Special Committe read a report on Medical Chemistry. Report received and discussed by Drs. Conner, Kincaid, Scoville, Miles, Bing, Hyatt, Gordon, Reed and Frizzell. At the close of the discus- sion Dr. Hyatt introduced the following resolution which was unanimously adopted: Resolved, That the sense of this Society is that a better knowledge of Medical Chemistry, on the part of students preparatory to entering the profession is demanded, and that the profession of Ohio is pledged to the work of bringing about a reform in this department of medi- cal education. - Dr. W. W. Seely read a report from special committee on “Otology.” Report received and referred to Com- mittee on Publication. Dr. Gay of Columbus, presented to the Society speci- mens of wire gauze apparatus for treatment of fractures. Society then took a recess until 2 o’clock P. M. Afternoon Session. The society met at 2 o'clock and was called to order by President Dr. Dawson. Vice President Dr. Landon took the chair while Dr. Dawson reported a case of Re-fracture of the Femur. The Doctor exhibited drawings showing the condition of his patient prior to the re-fracture and also showing the happy result of the operation. Remarks on the case by Dr. Conner. Dr. Stevens moved that the thanks of the Society be tendered Dr. Dawson and that he be requested to write out his remarks on the subject for publication in the Transactions. Carried. During the afternoon session the following new mem- bers were elected. * Dr. J. P. Primrose, Nelsonville, Athens Co., Ohio; Dr. James Moor, Ironton, Ohio; Dr. C. B. Hall, Millers- port, Laurence Co., Ohio; Dr. Camillus Hall, Burlington, Ohio; VoIUNTEER PAPERS–REPORTS OF CASES. The President annouced that owing to the amount of business before the society Dr. Bartholow withdraws his paper on “Aneurism of the Basilar Artery.” Dr. A. Andrus read the report of a case showing the front surface of a body studded with tumors varying in size from a pea to a walnut. Report received, and discussed by Drs. Dunlap—who reported a similar case—Hyatt, Miller, Bartholow, Sin- nett and C. P. Landon. Dr. Miller, with remarks, reported a case which much resembled the case of Dr. Andrus, Dr. C. P. Landon, having seen the case of Dr. Andrus in consultation, gave it as his opinion that the tumors were due to scrofulous or tuberculous deposits. Dr. Bartholow spoke of the cases as possibly multiple adenoma which was known to be a very dangerous form of disease. To this suggestion Drs. Andrus and Miller replied that in neither of their cases were there any symptoms of implication of the glandular system; on the contrary, the family history of the patient proved a cancerous diathesis. Dr. E. Sinnet reported a case which bore some resem- blance to the cases of Drs. Andrus and Miller. The paper was then received and referred to Com- mittee on Publication. Dr. Gay moved that when the Society closes its meet- ing at this place it adjourns to meet in Columbus on the second Tuesday in June, 1873. Carried. The Society then adjourned until Thursday morning at 9 o'clock. - After adjournment the Society was entertained by a visit to the Holly Water Works, and the extensive shoe factory of Resenberrick, Drew & Co. At 9 o'clock in the evening the Society was entertained by the Board of Trade and the citizens of Portsmouth with a sumptuous banquet given in the Hall of Wil- helm's Opera House. The evening passed pleasantly ; good-eating, good music, good dancing, good “Big Med- icine Man” who administered to the thirsty in a way to be remembered by all who came under his treatment. T H I R D ID A. Y. Morning Session. The society was called to order by the President Dr. Dawson at 9 o'clock. - Prayer by the Rev. Mr. Stanly, of the Sixth Street Methodist Church. * On motion of Dr. Miller the reading of the minutes of yesterday's proceedings was dispensed with. Dr. Thad. A. Reamy exhibited an instrument of his own invention, for intra-uterine medication. He thanked Prof. P. S. Conner for valuable sugges- tions, during the time he was preparing his instrument. At the close of his remarks Dr. Reamy said he hoped the society would accept this report in lieu of the report which he was posted to have made on the “Surgical Diseases of Women.” Report received and referred to publication committee with orders to print. Dr. Thomas H. Kearney read, his report from special committee on Amputations. Report received and after remarks by P. S. Conner was referred to committee on publication. Dr. Bing moved that Dr. A. G. Sellards, of Vanceburg, Kentucky, be admitted to the courtesies of the Society. Carried. Dr. G. S. B. Hempstead, was at this juncture elected an honorary member of the Society. Dr Hempstead, retired from practice fourteen years ago, after having practiced forty-three years. He was one of the Original Members of this society, was its President in 1855; and is now its oldest living member, being seventy-eight years of age. - JUNE 22, 1872.] TEEE CI ITTI c. 299 The Finance Committe reports in the case of Dr. McClain in favor of his reinstatement upon his pnying into he treasury two-thirds of the amount he owes the society. Report received and adopted. Dr. J. T. Whittaker read a report. from Special Committee on “The Year's Contributions of Physiology to Practical Medicine.” Report received and referred to committee on publication. Dr. L. M. Jones, of West Liberty, read a report from standing committee on Obituaries, in place of the Chair- man, Dr. B. B. Leonard, who was not present. Report received, and, after some remarks by members to the effect that the report was not complete, since it did not embrace a notice of all who have died of our number the past year, was adopted. Dr. E. B. Stevens moved that a committee be appointed to report on the death of our late secretary Dr. W. C. Hall. Carried. The President appoined Dr. Stevens as the committee. - Dr. Miller was appointed a committee to report on the death of Dr. Cary, of Salem, Ohio. Dr. Alex. Dunlap was appointed a committee to re- port on the death of Dr. Kyle, of Xenia, Ohio. Dr. A. B. Jones requests that his report from special committee on “Relation of the Mental to Man's Physical Forces,” be read by title and referred to publication committee. - - On motion of Dr. Bing it was so read and referred. A communication was here received and read by the secretary, from Dr. Geo. Mendenhall, embodying the following resolutions: Resolved, That a committee of five, of which Dr. Clem- denin be Chairman, be appointed to prepare a memorial to the Legislature of this state, on the subject of Public Health, in accordance with the resolution of the Ameri- can Medical Association presented by Wm. Logan, of California. - Resolved, That this committee co-operate with Dr. A. E. Jenner in reference to the bill presented by him in the Senate of Ohio. Resolved, That this committee shall prepare a suitable memorial and have five hundred copies printed and dis- tributed to the members of this society for signature; and draw upon the treasurer for the amount expended for same. - Trusting that the members will consider this subject, favorably, - On motion of Dr. Conner the resolutions of Dr. Men- denhall were so amended as to instruct the committee to report upon the subject of a State Board of Health at the next meeting of this society. * Dr. Clendenin not being a member of this society, the President appointed Drs. Geo. Mendenhall, J. R. Black, P, S, Conner, G, B, Orr, Geo, E, Walton, com mittee on State Board of Health, Dr. Miller stated that Dr. Joel Pomerine had a report ready from special committee on Puerperal Convulsions but was unable to be present to read his report and therefore requested to be continued on the same com- mittee until next year. By vote of the Society Dr. Pomerine was continued as he requested. President Dr. Dawson gave a synopsis of his valedict- ory address, which was well received. The subject was that of medical education. The annual wail and lamen- tation on that topic was not indulged in by the speaker; a more cheerful view was taken of the question. The speaker showed how rapidly we had advanced in that respect within the past twenty years, how our works on medicine were translated into foreign languages and read abroad. He also referred to the general diffusion of education by our system of public schools, and how they were auxiliary to medical education by preparing the youth of our land with a thorough primary education. On motion of Dr. E. B. Stevens the President’s address was referred to the Publication Committe with instructions to print. The President announced the following z- STANDING COMMITTEES: Evecutive. N. Gay, J. B. Thompson, J. W. Hamilton, C. P. Landon, R. M. Denig. Publication. J. W. Hadlock, W. J. Conkling, E. B. Stevens, S. S. Gray, C. M. Finch. Medical Societies. J. P. Bing, M. S. Pixley, Louis Schwab, A. C. Miller, J. H. Green. Finance. L. M. Jones, E. Jennings, E. B. Stevens, C. M. Finch, D. D. Bramble, Admissions. M. Cassat, N. S. Hill, S. S. Scovill, T. W. Gordon, E. H. Hyatt. Obituaries, T. W. Gordon, David Cotton, E. H. Hyatt, E. Sinnett, Alex. Dunlap, SPECIAL COMMITTEES. Castration for Epilepsy—M. S. Pixley, Portsmouth. Quinine—S. S. Gray, Piqua. Progress of Surgery during the year—P. S. Conner, Cincinnati, J. L. Wylie, Easec- tion of the Hip Joint—D. D. Bramble, Cincinnati. In- sanity—D. A. Morse, Midway. Therapeutics of Alcohol. —E. H. Hyatt, Delaware, Consumption in Ohio Pen- etentiary—N. Gay, Columbus, Stricture—A. C. Miller, Cincinnati. Ophthalmology—J. H. Buckner, Cincin- nati, Syphilitic Affections of the Nervous System—W. J. Conklin, Dayton, Nervous Diseases—R, Bartholow, Cincinnati, Pathology and treatment of Diphtheria and Scarlet Fever—J. W. Hoff Small-Pow—E. Jennings, Dayton. The distinction between Caseous Pneumonia and True Tubercle—A. T. Keyt, Walnut Hills, Cincinnati, O. Urinalysis—J. W. Russell, Mount Vernon. Functions of the Spleen—S. S. Scoville, Lebanon, Cerebro-Spinal Meningitis—A, B, Monohan, Lebanon. Skin Grafting—T. D. Davis, Lebanon Gastric Irrigation—E. Sinnett, Gran- 300 [JUNE 22, 1872, T TEI IET: C T , T TNT I C. ville. Nervous Diseases—N. S. Hill, Newville. Incura- ble Diseases—J. P. Bing, Portsmouth. New Remedies—C. R. Reed, Middleport. Trêtment of Ulcers and other Cuta- neous Diseases of the Lower Ertremities—C. M. Finch, Portsmouth. Efficacy of Vaccination—David B. Cotton, Portsmouth. Small-Poac—A. G. Stevenson, New Rich- mond. Small-Poa:—M. Cassat, Cincinnati. Shoulder Pre- sentations—W. V. Peck, New Richmond; Epilepsy—N.S. Hill, Newville. Cataract—W. W. Seely, Cin- cinnati. SPECIAL COMMITTEES CONTINUED FROM LAST YEAR. Therapeutics—H. J. Herrick, Cleveland. Ovariotomy—A. Dunlap, Springfield. Vaccination— W. B. Davis, Cincinnati. Pverperal Convulsions— J. Pomerine, Millersburg. Therapeutics of Mineral Springs —G. E. Walton, Cincinnati. Gynaecology—C. D. Palmer, Cincinnati. Chronic Diseases of the Lungs— W. Carson, Cincinnati. Obstetric Record—J. Helmick, Cleveland. Electrolysis—W. H. Mussey, Cincinnati. Belladonna—J. A. Little, Delaware. Diseases of the Laryna-R. Wirth, Columbus, Uterine Diseases—E. B. Stevens, Cincinnati. Diseases of the Skin—C. O. Wright, Cincinnati, Prevailing Diseases throughout the State—J. R. Blacky, Newark. Inflammations of the Chest—J. A. Murphy, Cincinnati. Physiology—J. T Whittaker, Cincinnati. Uterime DELEGATES TO THE AMERICAN MED, ASSOCIATION, E, S. Hyatt, Delaware; L., M. Jones, West Liberty; E, Sinnet, Granville; M. Cassat, Cincinnati; L. Schwab, Portsmouth; J, D, Cotton, Marietta; E, Jen- nings, Dayton; C, R, Reed, Middleport; J, B. Hough, Ridgeview; John W, Russell, Mt. Vernon; S. S. Scovill, Lebanon; C. P. Landon, Westerville; A, J, Miles, Cincinnati; T, H, Kearney, Cincinnati; R., W. Erwin, Athens; J. W. Hadlock, Cincinnati; A. C., Brainard, Olmstead Falls; S, S. Gray, Piqua; A. Dun- lap, Springfield; J. B. Thompson, Columbus; N, Gay, Columbus; Thos, W. Gordan, Georgetown; G' W. Pullin, Logan; A, C, Miller, Orville; W, F, Paige; Johnstown; Joel Pomerine, Millersburgh; J, R., Black, Newark; Dudley Allen, Oberlin; W. T. Ridman, Toledo, J. C. Brown, Urbana ; John Bennett, Cleveland; H. Culbertson, Zanesville; H, S, Conklin, Sidney; L, S, Ebright, Middleburg; W, P, Kincaid, New Richmond; B, Gundry, Dayton; W. L., Peck, Columbus; G, Mitchell, Mansfield; J, C. Hubbard, Ashtabula; David Noble, Hillsboro; T, G, McEbright, Akron; W, D, Scarf, Bellefontaine; O. G., Seldon, Shaneville, DELEGATES TO STATE MEDICAL SOCIETIES, Indiana—W. H. Mussey, J. W. Hamilton, C. M. Finch, A, H. Agard, W. J. Conklin. Rentucky—T. W. Gordon, J, T, Whittaker, H, C, Brainard, G, W. Brook, S. Loring. New York—J. A. Murphy, T. A Reamy, S. S. Gray, H. J. Herrick, B. F. Miller, Illinois—P. S. Conner, J. A.Little, J. P. Wylie, Roberts Bartholow, C. B. Reed. Ransas—E. Sinnet, S. S. Scovill, W. W. Seely, J. H. Buckner, J. N. Burr. Western Virginia—E, B, Stevens, A, T, Keyt, T, H, Kearney, J. P. Bing, J, W, Russell, Jr, Dr. E. B. Stevens introduced the following resolutions, 1st. That the thanks of the society are due to the officers of this session for their ability and impartiality. 2nd. Resolved, That we return thanks to the several Railroad Companies who have extended their courtesies to the members in attendance. 3rd. Resolved, That we are especially indebted to the Profession, the Board of Trade and to the Citizens gen- erally of Portsmouth, for the magnificent hospitality and thoughtful attention which we have received ; in the words of Rip Van Winkle, “May they live long and prosper.” [A rising vote was given in the affirmative to all the above resolutions, when twelve minutes to 12 o'clock M. the gavel fell and the twenty-seventh annual meeting of the Ohio State Medical Society was declared adjourned to meet in Columbus on the second Tuesday in June, 1873, Portsmouth situated in a broad valley and surrounded by beautiful hills with her genial hospitable citizens will long be remembered by all those in attendance upon the meeting just closed. From the time we stepped upon her wharf until the steamer—which was to bear us home—left her shores, nothing but cordial hos- pitality greeted us on every hand; not a jar, not a dis- cordant sound, not an unpleasant thing to mar our remembrance of her and her citizens occurred during our stay of three days within her limits. J. W. H.] W. W. Dawson, President. J. W. Hadlock, W. J. Conkling, -º-º-º- | Secretaries, MEDICAL GOLI, EGE OF OHIO. THE FIFTY-SECOND annual session commences its preliminary course, as usual, Sept. 1, ’72. The regular term begins Oct. 1. Fees, etc. unchanged. The Col- lege, it is useless to state, preserves all its peculiar advantages for instruction in every particular. Prelim- inary Announcements exhibiting some new features in the way of increased facilities now in press. Circulars with detailed information sent to any address by the Secretary. Prof. W. W. Seely, Secty. Prof. J. Graham, Dean. Portsmouth—State Medical Society. To the Editor of the Commercial: , , , , /r??. It was my privilege to attend the twenty- seventh annual meeting of the Ohio State Medi- cal Society in the beautiful and hospitable city of Portsmouth. Portsmouth is indeed a beauti- ful little city—beautiful in itself, beautiful in its surroundings. It will be long before I forget the lovely frontispiece given to this place by the green, fresh Kentucky hill on the opposite Shore. Long may its Verdure remain to bless and delight the generous people who dwell at the junction of the Ohio and Scioto. Of these citizens—the noble men, the lovely women—we can hardly find Words to express our high ap- preciation. To doctors worn and weary with Work, and more... used to the rough than the th Đhase of life, the deligate civilities mani- fested on all sides were peculiarly refreshing, D.R. G. S. B. HEMPSTED, . On the stand Was this Venerable man. Tyr. Heppsted has been practicing medicine fifty- eight years, and is still hale, hearty, and able to work. A doctor for fifty-eight years—thunk of it! THE DRs. COTTON. We met here three brothers, §. physi- eians, Dr. John Cotton, of West Virginia, ix. J. D. Cotton, of Mariettà, and Dr. D. B. Cotton, of Portsmouth. They are the sons of , one of the earliest and most distinguished physicians of Ohio. Dr. Cotton, besides having these three sons, who now represent him in the profession, had two daughters, both of whom married hysicians. The high character of Dr. Cotton as been transmitted to his sons. It has seldom been my fortune to meet three more dignified and refined gentlemen. MR. DUGAN, COLONEL MOORE, COLONEL COATES - AND JUDGE THOMPSON Took charge of the doctors during the afternoon of Thursday, and in elegant carriages and be- hind spirited horses, showed those sons of Escu- lapius the surroundings of the city... So genial, so pleasant, so entertaining were these gentle- meñº" he whistle of the steamer was truly an unwelcome sound. Mr. Dugan exhibited his “talking dogs.” . Colonel Mooºshowed us how “premises might be correct, but conclusions wrong.” Colonel Coates dispensed the hospitali- ties and judge Thompson proved by his anec- dotes that he had seem dogtofs, • THE PORTSMOUTH DOCTORS, Doctors Finch, Jones, Bings Pixley, Schwab and Cotton were untiring in their efforts to ren- der the stay of the Visiting brethren pleasant. THE MEETING. The meeting was pronounced by all present as i. f * * , *, } , . . ; tº “. & } \. # Uk * * /* , - L, MONDAY, JUNE 17, not only the most pleasant, but o y Ile Of ſºle held in the State for years. #.§§ l Tº learned and most of the discussions were Olear and to the subject. REV, DR. BURR. Por more than a third of a cent º Ulry thi • 㺠r • € t §.e. on Tuesday morning, and .*.*...; S º # calm,. benignant face, and heard his , tender voice, now Sºal Cely tremulous at ( I the age of sixty-eight, we felt th * y at cy” *- tinuange in one fiéià of labor was § º: £ºſe: , May his sheaves at th * embrace all the people of #;" *Yºst ºr. º their l be educated without impairing their r and made known on day of sale. Ct and sale positive. ſuses Will leave the office of Hemmel- [48 Main street, Cincinnati, at 1 o’clock, 3 of H. DeGruyter & Co., Sheriff's office, Cy., at 1% o'clock, and Newport Court- 2 at 1% o’clock, to take persons to and free of Charge. jë15-3t-HemózCod. DeG&Co by Robert J. Cresap, Broker and General Auctioneer, Nos. 272 Central av., above Seventh, Cin. Sale—Six Building Lots, on Spring venue, Addison and Cook Streets, at (Monday) AFTERNOON, June 17, ., will be sold at public auction, on the ose six Building Lots on Spring Grove son, and Cook streets; also, a good lot nd Addison Streets. Terms—Ofeathird ance in One and two }. These lotS ed, about two squares from the Brighton the same distance from the new Stock 3 indisputable and sale positive. any person, desiring to purchase good s, in a good location, convenient to street }roperty is increasing in value evºy §y, x-CI: are opportunity. epohl, Bender & Enneking, gents and Auctioneers, Office No. 32 West Court Street. d Saloon, Corner of Fourth and ill Streets, at Auction. UESDAY MORNING, June 17, the undersigned will sell at auction, on a splendid stock of Groceries, all lately sons désiring to purchase will find this a pportunity to secure §§ bargãins on Bsh goods. Will be sold by the whole or OSitive. TêImS Cash. je16-3t-H,B&E Hoeffer & Bueming, gents and Auctioneers, 652 Race St., pposite Findlay Market, Story Brick Building, with Lot, e Street, No. 167, at Auction. n MONDAY, June 17, 1872, the premises, on the South side of 167, between Linn and Baymiller sts, 2-story brick dwelling, containing 6 , cellar, hydrant, Cistern and a splen- lanted With viness The lot has 25 feet 'eet, more, or léss, in depth. This i chance to all désiring to procure dence in the western part of the city is raising in value, on a nice stree lent neighborhood, or to those wishing rable investment, Title good. fourth Cash, balance in 1, 2 and 3 years, secured by mortgage on the premises. jelá-3t-14,16,17-Hé.E. . are, of course, that immenºś jºi to conduct a Presidentiº jºispeakers are to be paid: ic; special trains are to be paid for; f dollars are to be urnals. Other items could be which are inseparable from expº cal campaigns. iation will be ind in Pennsylvania.” } ECRET at the O 137 Sycam | Manhood tute in the 3. - the only knº confidential ture. Send Separate en See perfect cured, and t tute and Se tlent S, is a D A. REGU (as diploma his Special a eases. ReCé are treated and Impoter or excesses, fects: as em dizzineSS, Iae Stipation, CO of memory a for business Sanity or CO nently CUTed fines himself Class of dise specialty tha matter Who cured. The om 12 A. M. Street, betwe 66 & OUNG IV yourselvé nervous, wea. IneSS, marriag pliance for se cure. Price $ Middle-aged vance of thei reg. you €TSOIAS SUlf especially tho no time in ma Female dise mali $5. Con, bet. Central av of money -Caſmpaign. thousands of anners to be raised in all parts of the Repu * ertising im Imany paid for adver ºã in all polit- Money collected by this 98.39. ăiº, in the Western States Then followed the names of officers box 953, Cinc Rºº-ºº: thousands ent office and received similar = E−i–Š 4-2-º- s º rºa -tº- ion. ur years ago I Was in a º: Four y g COIſl{d. of Said a S- Govern- At DIVIDED MEDICINES, C’REPAIRED BY The Divided Medicine Com’y, CINCINNATI, OHIO. The Company have the honor of bringing to the notice of the Profession, this NEw AND ExcEEDINGLY PRAUTICAL METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. The Divided Medicines are prepared by FREDERICK KRAUs, Chemist of the Company, with the most scrupulous accuracy, according to the rules-of Pharmacy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and No MORE. The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every Square will consequently contain accurately measured quantities. But not only SoDUBLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate division into the form of DIVIDED MEDICINES. & • This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, ; , , , ºo, and even idoo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE To SPOIL BY ANY LENGTH of TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, use they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calls with good accurately dosed medicines; and that these medicines have the Superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. ' For Samples, Price Lists, and Agencies, address Divided Medicine Coe I-3CIX 2688, Or FRFDERICK KRAUS, Chemist and Druggist, t Walnut Hills, Cincinnati, O. MR. FREDERYCK KRAUs: CINCINNAT1, February 15, 1871. Dear Sir—The specimens of your “ Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: SULPH:MORPH II....................... % grain in each square. ARSEN: ACID.......................... 1-20 grain in each square. ** CHINTNI .......................] ‘‘ ‘‘ {{. CALOMEL % “ • & { { * COPPER........ * > * tº gº º ei º •......}% $3 RESPECTFp LLY Youps, E. S. WAYNE, Analytic Chemist O D O E& L E S S A. IN ID PA I L. A. T. A. E. L. E = In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by . Messrs. MARVIN BROTHERs & BARTLETT, of Portsmouth, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. In order to secure the best medicinal effects, Cod Liver Oil should be derived from the per- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachilic Affections, in Chronic Rheumatism, &c. The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. JAMEs Fosºrºr, Jr. & co. [ESTABLISHED, 1836.j Importers and Manufacturers of Optical and Physical Instruments, eep constantly on hand first-class English and French Microscopes, First-class objects and Mieroscopical Apparatus ºf every descrip- tion, Mestical Batteries, Thermometers, t Hydrometers, Urinometers an Chemicai Glass Ware. *. attention given to adapting the best spectacles to all conditions of signt. We take pleasure in showing the latest novelties from the best Euro- pean and American manufacturers. JAMES FosTert, Jr. & Co., **. S. W. cor. 5th & Race Sts., Cincinnati, 0. IXER, 5.IN.INMARSH's º º s Nsº ºrE:º Q No. 758 Bao ADw Ay, New York HAVE been in the habit of applying and recommending the Truss, manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined. LEWIS A, SAYRE, M. D. Surgeon, Bellevue Hospital. ** * From Prof. Willard Parker to S. D. Tówásends M. D., Surgeon to the Massachusetts General Hospital. #EG leave to state for the benefit of all concerned, that I have known Dr.'s. N. Marsh the last fifteen years. * * * I am in the constant habit of sending my patients to him for treatment. I have been delighted with his Truss, and the sūccess he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with anv of the risks to the patient that exist in many of the plans suggested and attempted to be carried into execution. I have confidence in Dr. Marsh as a gentleman of honor and integrity, and as such recommend him to the nearbèrs bf the medi- cal profession generally. WILLARD PARKER, M. D. Professor of Surgery, New York City Af Dr. S. N. Marsh's Patent Radical Cure Truss and all other kinds of Trussés, shoulder Braces, Supporters, Elastic stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Oure Truss Offices of S. N. MARSH & CO., No. 2 Wesey St. (Astor House), New York, and S. N. MARSH, CORLISS & CO., No. 8 West Fourth St., between Main and Walnut, Cincinnati. d OPPOSITE THE HIGH STEEPLE, sº Agonts for Clement's Patént Artifióial Legs. F. E. SUIRE. E. S. WAYNE F. E. suire & Co., wholesale DRUGGists, IMC A. IN TJ E" A C T TJ IE, I INT G- £HEMists AND PHARMAceutists, CINCINNATI, OHIO. Have constantly on hand a full assortment of sex,xec ºxex) ox3. UGs ANOO myxxe)oxc)(N)es, ckxxeryxxcAx. AxºpAx{A^eus, TESTs, MEDICAL, GLASS WARE, &c, &c., And solicits the patronage of the trade and profession. We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, iſºde in accordance with the U. S. P. and other recognized authori- ties. ITINIFD AND R A RHC CHEMICALs, Of the popular class of preparations known as IE T, ILK! I ER, S, We manufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which # the nauseous taste of medicines are disguised, and they made pleasant to take. Bitter Wine of Iron, An excellent Chalybeate and tonic, Wine of Iron, &c. AGENTS FOR BULLOCK & CRENSHAW'S Sugar-coated Pills and Granules. Price Lists of preparations and of Sugar-coated Pills sent by Mail upon application. The long standing and well and widely known repu- tation of our house we offer as a guarantee for the reliability of our preparation, and the quality of the goods sold by us generally, Tw illiam Autenrieth, ROBERT GLARKE & G0.’S No. 71 WEST sIXTH sº REET, BETWEEW WAINUT AND WINE, CINCINNATI, OHIO, MANUFACTURER OF AND DEALER IN || || || ||||||||| Abdominal Supporters, Trusses, CLUB-F00T SHOES, SPINAL APPARATUS, ETſ Keeps constantly on hand a full variety of Metalic and ERubber Syringes, Stomach Pumps, Etc. STOCKINGS FOR WABDCOSE WEDNS, Special attention given to the fitting of Apparatus for Deformities. gº Agent for DR. L. A. BABCOCK'S Silver Uterine Supporter, -ALSO– DR. AHL's POROUS FELT SPLINTS, -ALSO- T) A. Y. * S S EP T, IN T S -AND- 8. W. Elliott’s Saddle-bags LIST OF NEW MHL iBTH in Mºulis Hill; HEWSON, A. Earth as a Topical Application in Surgery. $2.5o BROWN, J. H. B. Medical Jurisprudence of Ihsanity. $4.5o HARLEY, GEO. The Urine and its Derangements. $2.75 ALLINGHAM, WM. On the Rectum. $2 5o SCHELLEN, Dr. H. Spectrum Analysis. Colored plates. $6 oo LUBBock, Sir JNo. Prehistoric Times. Illustrated. $5 oc HUXLEY, THOS. H. Manual of the Anatomy of Vertebrated Animals. $2 5o HINTON, JAS. Man and his Dwelling Place. $1 75 FONTAINE, E. How the World was Peopled. $2.5o MITCHELL, S. W. Injuries of Nerves, and their Consequences. $3 oo DRAKE, F. S. Dictionary of American Biography, including Men of the Time. 8vo. Cloth, $6 oo; Sheep, $7 oo; Half Morocco, $8 5o. FOTHERGILL, J. M. Digitalis; its Action and Use. $1 25 WUNDERLICH, C. A. Medical Thermometry and Human Tem- perature, $2 oo ALLEN, P. Aural Catarrh.. $2 oo GANT, F. J. The Irritable Bladder. $250 HOLLAND, Sir HENRY. Recollections of Past Life. $2 oo TAINE, H. English Literature. 2 vols. $10 oo TAINE, H. Notes on England. $2.5o CLARKE, E. H., and AMORY, R. Bromide of Potassium and Ammonium. $1 5o 3: MARKOE, T. M. Diseases of the Bones. $4.5o SIMPSON, Sir J. Y. Diseases of Women. $3 oo BUCK, G. Lithotomy and Lithotrity. $1 oo TANNER, T. H. Memoranda of Poisons. 75 ctº HENRY, M. H. Treatment of Venereal Diseases, as treated in the Vienna Hospital. $1 oo * COBBOLD, T. S. On Worms. $2 oo APPLETON'S Hand Atlas of Modern Geography. $2.5o BEETON'S Dictionary of Geography. $3 75 TOWNSEND, G. H. The Every Day Book of Modern Literature. $375 How, J. Freemason's Manual. $4 25 DANA, JAS. Corals and Coral Islands. $6 oo LYELL, (Sir CHAS.) Principles of Geology. 2 vols. $12 60 CURTIS, G. T. Life of Daniel Webster. 2 vols. $6 oo HERSCHEL, Sir JNO. Outlines of Astronomy. $4 oo LECKEY, W. E. H. Leaders of Public Opinion in Ireland. $175 CURTIUS, Prof. E. History of Greece, 3 vols. $7 50 MACAULAY, Lord. Complete Works. 4 vols. New ed. $9 oo RECLUS, ELISEE. The Earth. $5 od MALTHUS, T. R. Principle of Population. $4 oo THOMAS, T. G. Diseases of Women. Cloth, $5 oc; Sheep, $6 oo ASHURST, JNO. Principles and Practice of Surgery. Cloth, $6 5o; Sheep, $7 5o ** SMITH, J. L. Diseases of Children. Cloth, $5 od; Sheep, $6 oo Medical, Scientific, and other Catalogues sent on application. Any book in the above list sent by mail or express, free of charge, 1 on receipt of price. 65 West Fourth Street, Cincinnati, Ohio. List of Pharmaceutical Preparations, MIANUFACTURED BY Jonºv wrºzºr & amozwan, PHILADELPHIA. —º- ELIX. PHOS, IRON, QUININE AND STRYCHNIA, ELIXIR OF GENTIAN FERRATED, ELIXIR, WALERIANATE OF AMMONIA, (Goddard’s Formula,) ELIXIR VALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, Iron, with Phosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Iron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK, * ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND SYRUP OF HYPOPHOSPHITES, COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER WINE OF IRON, Citrate of Iron amud Peruvian Bark, FERRATED CORDIAL ELIXIR, ELIXIECALISAYA BARK, WINE AND BISMUTH, ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, º FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, TASTELESS COD LIVER OIL, TASTELESS COD LIVER OIL. FERRATED, BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and sherry Wine, ELIXIR WALERIANATE OF STRYCHNIA, WINE OF PEPSIN SYRUP SUPERPHOSPHATE OF IRON. D ELIXIR OF BISMUTH, COMP. FLUIDEXT. BUCHU AND PAREIRA BRAVA. slº.J EPIE OSITOTER, MIES. Rectum, Waginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great eare, and of every variety of combination. Lists sent on application. SPONGE TENTS.—For the Urethra, of every size and style, made of finest quality of sponge. P ºNº- V. - º : ..| ºW. || § * *...* - *-* * * Słº-zz-sº 2 * ~ ; º ...Nº Nºv ºv sº. - ** ºn §º ºr wº º: E. | " : | --- - sº. ". * ºf ... 8 º NºżS. *- CINCINN ATI. E" A C U L T Y. J A M E S G R A H A M , M. D., D E AN, Professor of the Theory and Practice of Medicine and Clinical Medicine. ROBERTS BARTHOLOW, M.D., W. W. DAWSON, M.D., Professor of Materia Medica and Therapeutics. Professor of Principles and Practice of Surgery and Clinical Surgery. W. H. GOBRECHT, M.D., T. A. REAMY, M.D., Professor of Obstetrics and Diseases of Children. Professor of Anatomy. JOHN L. CLEVELAND, M.D., P. S. CONNER, M.D., Professor of Surgical Anatomy. Demonstrator of Anatomy. JAMES T. WIIITTAKER, M.D., Professor of Physiology. CHARLES KEARNS, M.D., Assistant to the Chair of Surgery. SAMUEL NICKLY'S, M.D., Professor of Physics and Medical Chemistry VV. V.V. SEFCLY, IN.I. D., I’rofessor of Diseases of the IEye and Far, and Secretary of the Faculty E. NoBLE, Janitor, College Building, Sixth St., bet. Vine and Race .*** **- T. LOUIS BROWN. M. I.). Prosec to of Anatomy. *a*aeaeºſºl-CºA-aa– ~~~&l-tº-aa-ºeſºté Nº. 225S-7 S-ZT*S*TS-7 St’CŞSºNEL:) º º e-ºr-ee-va-E-p l →º – Published ºx ery saturday. - •º gº * * - ºr-º- tºs - * ... ºf a CINCINNA Pi, JUNE, 1872. # 4 == £ºr # INDEX Tö-WoLUME II. + .* → – ‘.…" . ** º, '- *TE: Ft. MIS = Two Dollars a Year, - - - * - -> In variably in Advance CLUB RATES– Four Copies to one address, 4- - sº – $7.OO • , , six “ & C & 4 — — — — 1 O.OO - . Twelve “ & & K & — — — — 18. OO --- ~~, ;" All Communica..., relating to Publications must be addressed to the Editor. All Communications slating to Business, Subscriptions, Advertisements, etc., to the Treasurer. x', *. - sº- PROSPECTUS FOR vol. III | 1819. Malºlºſ), 1872. The ſºn IC, Hiſtºrmi Annual jºim. PUPI,ISEIIBID EVERY SATURDAY. The Preliminary Lectures of this, the Oldest Med- ical College in the West, commence Sept. 1st; the A Volume of 624 pages a year of Choicest Read- Lectures of the Regular Term, Oct. 1st, 1872. ing Matter. The graduating class of last session, ninety, ranks Original in its Original Matter. this institution First in the West, Third in the United • * º States. Select in its Selections. * tº e All the peculiar advantages and acilities for in- The Cream of Domestic and Foreign Medicine, struction have been materially increased. Fresh from their Sources. THE DISPENSARY has about 4,000 patients per The only Journal in the West published Once a year, all of which are examined before and by the Week. students, who are thus familiarized, under the guid- The Cheapest J ournal in the World. ance of their teachers, with physical diagnosis, meth- ods of minor operations, and prescribing. Trice, Two Dollars per Year. THE HOSPITALS are open alike to all students, s-mºm- without exception, on the payment of $5. THE GOOD SAMARITAN HOSPITAL is still The Company having been at infinite pains to under the immediate control of the Faculty. secure competent printers under their immediate Fees, $410.00. Send for circular. control, can assure the profession of the continued º W. W. SEELY, M. D., Sec'y. regularity of its appearance. JAS. GRAHAM, M. D., Dean. ——º-e-Cel-e- PRINTED AND PUBLISHED BY THE CLINIC PUBLISHING Co. § *- * $92-N 2- w) * Gº & fºre-seºte: º ſº I Nſ O. E. × - lºst Numbers, stian sil, smid ſº. A. Abscess, Cerebral, Trephined. . . . . . . . . . . . . . . . . ... 311 Abscesses, Multiple. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 Abscesses, Spleen . . . . . . . . . . . . . . . - . . . . . . . . . . . 196 Academy of Medicine . . . . . . . . 156–199–207–240–246–258–271 Accident in Laboratory. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42 Actonian Prize . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 Adenoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 241–271 Aethylidenchloride . . . . . . . . . . . . . . . . . . . . . 152 Agenesis Oculorum . . . . . . * * * * * * * * * * * * * 309 Agglutination Method * * * * * * * * * * * * * * * * 190 Agoraphobia . . . . . . . . . . . . . . . . . . . . . . . . . 61 Air Exhausting Apparatus . . . . . . . . . . . . . . . . . . . . 62–145 Alaska, Diseases of . . . . . . . . . * * * * * * * * * * * * * * * * * * * 24 Alcohol, Action of . . . . . . . . . . . . . . . . . . 140 Alcohol and Amblyopia . . . . . . . . . . . . . . 148 Alcohol at different Periods Life . . . . . . . . . . . . . . . 155 Alcohol, Coffee, Tea, etc. . . . . . . . . . . . . . . . . . . . 204 Allen's Aural Catarrh . . . . . . . . . . . . . . . . . . . * * * * * * * * * * 251 Amaurosis, Tobacco . . . . . . . . . . . . . . . . . . . . . .222 Amblyopia, Masturbation . . . . . . . . . . . . . . . . . . . . 288 American Medicine . . . . . . . . . . . . . . . . . . . . . . . . . . 58 American Medical Association . . . . 149–177–188–228–229–261 American Infecundity . . . . * * * * * * * • * * * * * * * g 67 A mour de la Patrie . . . . . . . . . . . . . . . . . . . . . . . 203 Amputation Cervix Uteri. . . . . . . . . . . . . . . . . . . . . . . . 145 Anaesthesia, Inventor of . . . . . . . . . . . . Anderson Lamp Bracket . . . . . . . . . . . . . . . . . . . . . . . 13 Aneurism, Foreign Bodies in . . . . . . . . . . . . . . . . . . . , 311 Animal Hospital . . . . . . . . . . . . . * * * * * * * * * s a s 125 Animal Laboratory, Physiology . . . . . . . . . . . . . . . . . . . 9 Anstie's Neuralgia . . . . . . . . . . . . . . . . . . . . . . . . 82 Anthracosis Pulmonum . . . . . . . . . . . . . . . . . . .91–102–114 Antidote to Carbolic Acid . . . . . . . . . . * * * * * * * * * * * * 84 Arsemiate Quinia in Tetanus . . . . . . . . . . . . . . . . . . . . . . 144 Ashurst's Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68 Atrophy Progressive Muscular. . . . . . . . . . . . . . . . . . . . . 218 Atropia, Antidote to Opium . . . . . . . . . . . . . . . . . . . . . . . . . 54 Autoplasty, Hand . . . . . . . . . . . . . . . . . . . . . . . 228 B Baby Farms. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141 Baker Brown, Relief for . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249 Bamberger's Introductory. . . . . . . . . . . . . . . . . . . . . . . . . . 262 Bartholow, Review Brown-Séquard. . . . . . . . . . . . . . . . . . 169 Battery, Good Samaritan Hospital . . . . . . . . . . . . . . . . . . . . S5 Bed-Sores, Galvanism in . . . . . . . . . . . . . . . . . . . . . . . 252 Belladonna against Mammary Secretion. . . . . . . . . . . . . 4 Bellevue Medical College . . . . . . . . . . . . . . . . . . . . . . . . . . . 189 Bennet's Consumption . . . . . . . . . . . . . . . . . . . . . . . . . . 70 Benzine in Whooping Cough . . . . . . . . . . . . . . . . . . . . . . . . 204 Berlin Battle . . . . . . . * * * * * * * * * * * * * * * * * * * * * * * * * * 8 Bladder, Puncture of . . . . . . . . . . . º 10 Bladder, Rupture of . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 Blepharospasm . . . . . . . . . . . . . . 153 Boast Not . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .307 Bogus Medical Colleges. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150 Books and Pamphlets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81–118 Bordeaux in lieu of Strasbourg. . . . . . . . . . . . . . . . . . . . . . . 305 Bound in Human Skin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189 Bromide Potash, Epilepsy . . . . . . . . . . . . . . . . . . . . . . . . . . . 204 Bronchocele, Injection in . . . . . . . . . . . . . . . . . . . . . . . . . . . . 264 Brown Scquard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225–307 Brown Sequard Lectures . . . . . . . . . . . . . 121–133–157 Bullet Explorers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 C Calculi Preputial . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 154 Camphor in Phag. Chancres. . . . . . . . . . . . . . . . . . . . . . . . . . 310 Cancroid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75–90–126–136 Captured Students. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 136–306 Carrier Pigeon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59 Catalepsy, Galvanism in . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 304 Cataract . . . . . * * * * * * * * * * * * * * * * * * s = e º ºs e s e º a e s tº a 83 Catarrh, Middle Ear. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181 Catheterism in Age . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 Census Statistics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 286 Cephalaeinatoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 281 Cerebro-Spinal Meningitis. . . . . . . . . . . . . . . . . . . . . . . . . . . 303 Cerebro-Spin. Mening. Conclusions . . . . . . . . . . . . . . . 213 Twenty-five Bound Copies of Volume II for Sale at $2.00 each. Cerebro-Spin. History . . . . . . . . . . . . . . . . . . . . . . . . . . . . 205 Cerebro-Spin. in New York . . . . . . . . . . . . . s & & 4 & 8 & º a 214 Cerebro-Spin, Morphia in . . . . . . . . ' ' ' ' - a . . . . 216 Cerebro-Spin. Pathology . . . . . . . . . . . . . . . . . . 211 Cerebro-Spin. Physostigma in . . . . . . . . . . . . . . . . . . . . . . 216 Cerebro-Spin, Quinia and Opium in . . . . . . . . . . . . . . 216 Cerebro-Spin. Recom. Am. Med. Assoc. . . . . . . . . 216 Cerebro-Spin. Review General . . . . . . . . . . . . . . . . . . . 209 Ceremonial Purification . . . . . . . . . . . . . . . . . . . . . . . . . 60 Charcoal in Gastric Dis . . . . . . . . . . . . . . . . . . . . . . . . . . 60 Chemistry of Hail . . . . . . . . . . . . . . * * * * * * * * * * * * * * 78 Chemistry, Progress in . . . . . . . . . . . . . . . . . . . . 104 Chloral, Clinical Researches . . . . . . . . . . . . . . . . . . . . . . 113 Chloral in Gout . . . . . * * * * * * * * * * * * * * * * * * * * * * * Chloral in Venereal Ulcers . . . . . . . . . . . . . . . . . . . . . 227 Chloral, Windication of . . . . . . . . . . . . . . . * * * * * * * * * * * * 99 Chlorate Potash in Dysentery . . . . . . . . . . . . . . . . . . . . 27 Chloride Ammon in Liver Dis. . . . . . . . . . . . . . . * * * * * * * 60 Chloroform in Robbery . . . . . . . . . . . . . . . . . . . . . . . . . 80 Cholera . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .21–141 Cholera in Russia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . , 242 Cholera in Turkey . . . . . . . . . . . . . . . . . . . . . . . . . . . & E. & 4 8 Cimicifuga in Small Pox . . . . . . . . . . . . . . . . . . . . . . . . . . 286 Circumcision of Corpses . . . . . . . . . . . . . . . . . . . . . . . . . . . 59 Cirrhosis of Liver . . . . . . . . . . . . . . . . . . . . . . . . . . 27 Clinic, Readers. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312 Closure Paris School . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189 Coal Dust in Lungs . . . . . . . . . . . . . . . . . . . . . . . . . . 91–102–114 College Dispensary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6) College for Siberia. . . . . . . . . . . . . . . . . . . . . . . . . . * * * * * * * 20 Compressed Air in Whooping Cough. . . . . . . . . . . . . . . 24 Qongress, German Physicians’. . . . . . . . . . . . . . . . . . . . . . 31 Conjunctivitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97 Conquest of Alsace . . . . . . . . . . . . . . . . . . . . . . . . . . . . 149 Constipation, Galvanism in . . . . . . . . . . . . . . . . . . . . . . . . 304 Cord, Dis. Gray Matter. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 198 Cormack, Honors to . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80 Corpulence . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 09 Correspondence . . . . . . . . . . . . . . . . . . . . . . 32–45–95–105–142—214 Creosote, Test for . . . . . . . . . . . . . . . . . . . . . * * * * * * * * * * * * 276 Criminal Jurisprudence. ... . . . . . . . . . . . . . . . . . . . . . . . . . . 139 Cross for Virchow. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167 Crotonchloralhydrate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 Croup, Treatment of. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 227 Curious Suggestion. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 94 Customs of Physicians B. C. . . . . . . . . . . . . . . . . . . . . . . . . 179 Cysts, Treatment of... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 D Dead on the Table. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 307 Death, Cause of . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 256 B.º.º.º. Progress of . . . . . . . . . . . . . . . . . . . . . . 160–172 Delpech, Bust of . . . . . . • * * * * * * * * * * * * * * * a tº e º ºs e s s a s : w w e 303 Diabetes and Fourth Ventricle . . . . . . . . . . . . . . . . . . . . . 44 Diabetes, Galvanism in . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 310 Diabetes Mellitus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 265 Diagnosis, Significance of . . . . . . . . . . . . . . . . . . . . . . . . . . . 166 Dickson, Dr., Death of. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 203 Digitalis on Anaphrodisiac . . . . . . . . . . . . . . . . . . . . . . . . . 132 Digitalis Action on Circulation and Temp. . . . . . . . . . . 146 Digitalis in Delirium Tremens. . . . . . . . . . . . . . . . . . . 267 Doctor, Title of. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Doctors Murdered . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 274 Dodge, Dr. I. S., Death of. . . . . . . . . . . . ** - - - - - - . . . . . . 120–155 Dogberry-cal. . . . . . . . . . . . . . . . . . . . . . . . . . . . . * > * * * * * * * * * 130 Dubois, Death of. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 Duchek, Liver Cirrhosis. . . . . . . . . . . . . . . . . * * * * * * * . . . , 27 Dupuytren, Anecdote of... . . . . . . . . . . . . . . . . . . . . . . . . . 141 Dysentery, Chlor. Potash in . . . . . . . . . . . . . . . . . . . . . . . . . . 27 Dysentery, Ipecac Enema in . . . . . . . . . . . . . . . . . . . . . . . . 74 Dysmenorrhoea. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 238 Dysmenorrhoea, Treatment of. . . . . . . . . . . . . . . . . . . . . . . . 23 E Ears, Laycock on . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176 Eclipse, Dangers of . . . . . . . . . . . * * * * * * * * * * * * * * * * * * * * 9 Eds. Med. Assoc. U. S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263 Educational Feature, New . . . . . . . . . . . . . . . . . . . . . . . . . . . . 202 Electrophysiologica. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 Electrotherapy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 304 THE C INI C. Pluſ BILISHED EVERY SATUR DAY, TER M S-$2.00 a Year, Invariably in Advance. All Communications relating to Publications must be addressed to the Editor: JAll Communications relating to Business, Subscriptions, Advertisements, etc., to the Treasurer. Vol. 2. C IN C IN N ATI, —dº J U N E 29, 1872. No. 26. JAS. T. VVHITTAKER, M. D. No. 101 West Ninth Street, Cincinnati. & sº tº Editor. WWII HM; EMI'lº, 0án & CO. t Pātītā Hālāſ; and l'Alèſ i Fashill, 92 FOURTH STREET, Opposite Post Office, CINTCINTINTA TT, C-, Bºy" The Oldest Established Hat House on the Street. “ºsſ. |Fine Silk Hats, Standard Quality $6,00. ----------- .* º º, .. º, **, * pºsic.NERS AN! W. W. SEELY, M. D., •º ºs º ºs º ºs TREASURER. No. 118 West Seventh Street, Cincinnati. Printed and Published by THE CLINIC Publishing Company, C L U B R A T E S, 4 Copies to one address $ 7.00 6 . $4. “ -------------------------------------------------------. 10.00 12 {< “. ........................................................ 18.0ſ) C O N T E N T S. - Page ORIGINAL ARTICLES HERNIA CEREBRI, by P. S. Conner, M. D......................................301 CFREBRO-SPINAL MENINGITIS, by J. R. Black, M.D......................... 303 TRANSLATEoN Electrotherapy, Collected from Various Sources (From Schmidt's Jahrbücher, April 18, '72.)................................................. ..304 ACADEMY OF MED}{CHNIE Transactions June 17, ”72. Meningitis by Drs. Whittaker and Ludlow—Stone by Dr. Mussey Uterine Fibroid, Specimen by Dr. Wood, Discussion by Drs. Reamy, Young, Wood, Dawson, Mussey—Intra-Uterine Medi- cation, Instrument by Dr. Reamy............................................. MIEDICAI, NEWS Havana Med. Students—Prof. Wm. W. Greene—Prof. Benj. How- ard–Honors to Prof. Sayre—The Munich Jubileo—A Millienial Celebration—Students at Strasbourg—Changes in Paris Facul- ties—Dr, Brown Séquard—Joe Jefferson’s Eyes—The Night Watches of Berlin—Female Med. Students—Dead on the Table —Boast Not 306–308 e e g º te sº a º ºs w a tº a tº * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * is º is º a º ºs e s is a vºw a e s º ºs s ∈ a wº Iº. EVIEWS A Treatise on the Diseases of Infancy and Childhood by J. L. Smith, M. D., New York—The Urine and its Derangements by Geo. Harley, M. D. London—Minutes Amer. Med. Association..308 cLINICAL MEMORANDA Extraction Fish-Hook from Oesophagus—Agenesis Oculorum—In- oculation of Small-Pox by Skin Grafting—Vesicants in Ear Diseases—Camphor in Phagedaenic Chancres—Galvanism in Diabetes—Treatment of Tremor of the Hand—Tapping and Strapping of Hydrocele—The Properties of the Principles of Opium—Treatment of Ulcerous Paronychia—Foreign Bodies in Aneurisms—Removal of Hair-Pin from the Bladder—Trephin- ing a Cerebral Abscess—Sea-Sickness—Double Uterus--A Two Pound Penis 309-312 To The Readiers of The Clinic. s = e = e s a s a s e º a se e s ∈ tº e a se e s s e < * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * ====s THE CLINIC terminates its second volume with this number, the last issue of the first half of the year. Subscribers from last August will of course receive their numbers regularly up to date of subscription when renewed orders must be prompt. With this number is forwarded an index of volume II. It is an index of the progress of the year. *ENGRAVERSoNWOO silicily NATI, ofio; sº, sº * * * * * J. TAFT, W. T.A.F.T. Editor Dental Fregister J. & W. TAFT, TDIEHINTTISTS 117 WEST FOURTH STREET, CINCININ ATI, O. The A Monthly Journal, CONTAINING 48 PAGES, Can you still afford to be without THE CLINIC 7 Devoted to the Interests of the Dental Profession, F. E. SUIRF. ... E. S. WAYNE É ſ: ſ #! ſº Importers and Manufacturers of Optical and Physical Instruments, Keep constantly on hand first-class English and French Microscopes, First-class Objects and Microscopical Apparatus of every descrip- tion, Medical Batteries, Thermometers, Hydrometers. Urinometers and Chemical Glass Ware. *. attention given to adapting the best spectacles to all conditions of signt. We take pleasure in showing the latest novelties from the best Euro- pean aud American manufacturers. JAMES FOSTER, Jr. & Co., S. W. cor. 5th & Race Sts., Cincinnati, 0. TER. S.INT.M.A.ER.S.H.’s gº) TRUSSES. F Gº E. suire & CO., 4. sº WHOLESALE ORUGGDSTS, TML A-IN U E A C T U ER, IIST G- £Hemists AND PHARMAceutists, • CINCINNATI, OHIO. Have constantly on hand a full assortment of S)ex,)&c.90 EXO O)6. U G. S ANYO IVX)e)0)(c)(N)es, cºeryocar, Ax-eas Aºcos, TESTS, MEDICAL, GLASS WARE, &c., &o., And solicits the patronage of the trade and profession. We would call attention to our select preparations, such as Solid and Fluid Extracts, Resinoids and Proximate Principles of Plants, Made in accordance with the U. S. P. and other recognized authori- ties. FINE AND RARE CHEMICALs. Of the popular class of preparations known as *. IE T, TIXII ER, S, We manufacture a full line. Those of our make may be relied apon as being what they are represented, containing the active agents in them in the quantity named. They will be found useful compounds, in which the nauseous taste of medicines are disguised, and they made pleasant to take. Bitter Wine of Iron, An excellent Chalybeate and tonic, Wine of Iron, &c AGENTS FOR BULLock & CRENSHAw's Sugar-coated Pills and Granules. Price Lists of preparations and of sugar-coated Pills sent by Mail upon application. The long standing and well and widely known repu- No. 758 BRoadway, New York I HAVE been in the habit of applying and recommending the Truss manufactured by Dr. S. N. Marsh, for the last eight years, to the ex- clusion of all others, and have found it to give general satisfaction, effect- ing a radical cure, in the majority of cases, in a very few months. As a Truss for the radical cure of Hernia, I think it far preferable to any I have ever examined. LEW 18 A. SAY RE, M. D. Surgeon, Bellevue Hospital. From Prof. Willard Parker to S. D. Townsend M. D., Surgeon to the Massachusetts General IIospital. B EG leave to state for the benefit of all concerned, that I have known lyr. S. N. Marsh the last fifteen years. st I am in the constant habit of sepding my patients to him for treatment. I have been delighted with his Truss, and the success he has met with in producing a Radical Cure of Hernia. He has instruments superior to any I have ever seen, and his treatment is unattended with anv of the risks to the patient that exist in many of the plans suggested and attempted to be carried into execution. I have confidence in Dr. Marsh as a gentleman of honor and integrity, and as such recommend him to the members of the modi- cal profession generally. WILLARD PARKER, MI. D. Professor of Surgery, New York City Dr. S. N. Marsh's Patent Radical Cure Truss and all other kinds of Trusses, Shoulder Braceh, Supporters, Elastic Stockings, Suspensory Bandages, Apparatus for Spinal Curvature, Club Feet, Bow Legs, and all other Physical Deformities, made and accurately fitted at the Radical Cure Trugs Offices of S. N. MARSH & CO., No. 2 Vesey St. (Astor House), New York, and 8. N. MARSH, CORLISS & CO., No. 3 West Fourth St., between Main and Walnut, Cincinnati. opposite the HIGH STEEPLE, gº Agents for Clement's Patent Artificial Lºgs. :ation of our house we offer as a guarantee for the reliability of our preparation, and the quality of the goods sold by us generally. MANUFACTURED BY List ºf Pharmaceutical Preparations, ** won.v. Irrazºn & arozzen, F.H.I.E.A.D.E.L.F.H.E.A. —-º- ELIX. PHOS. IRON, QUININE AND STRYCHNIA, * - ELIXIR OF GENTIAN FERRATED, ELIXIRVALERIANATE OF AMMONIA, - (Goddard’s Formula,) ELIXIRVALERIANATEAMMONIA AND QUININE, ELIXIR OF THE PYROPHOSPHATE OF IRON, Iron, with Phosphorous and Calisaya, FERRATED ELIXIR OF CINCHONA, Iron, Peruvian Bark and Choice Aromatics, ELIXIR OF CALISAYA BARK, - - ELIXIR PEPSIN, BISMUTH AND STRYCHNIA, COMPOUND syRUP OF HYPOPHOSPHITES, - COMPOUND SYRUP OF PHOSPHATES, OR CHEMICAL FOOD, Composed of the Phosphates of Lime, Soda, Potassa and Iron, BITTER WINE OF TRON, Citrate of Iron and Peruvian Bark, FERRATED CORDIAL ELIXIR, ELIXIR CALISAYA BARK, WINE AND BISMUTH, - ELIXIR CALISAYA BARK, IRON AND STRYCHNIA, WINE OF WILD CHERRY BARK, - - FERRATED WINE OF WILD CHERRY BARK, ELIXIR OF PEPSIN AND BISMUTH, - - - TASTELESS COD LIVER OIL, TASTELESSCODLIVER OIL. FERRATED, BEEF, IRON AND WINE, Extract of Beef, Citrate of Iron and Sherry Wine, ELIXIRVALERIANATE OF STRYCHNIA, WINE OF PEPSIN SYRUPSUPERPHOSPHATE OF IRON, ------, . . . . - ELIXIR OF BISMUTH, COMP. FLUIDEXT, BUCHU AND PAREIRA BRAVA. STUTE"I FOSITOTER, II ES. Rectum, Waginal, and Male Urethral Suppositories and Soluble Pessaries of Pure Butter Cacao, made with great eare, and of every variety of combination. Lists sent on application. SPONGE TENTS.—For the Urethra, of every size and style, made of finest quality of sponge. Wm. Wilson McGrew, JW2, Ž7 WESZ" Aſozºzºz Szºz, PIKE'S OPERA HOUSE BUILDING, wº Importer and Dealer —-weea I N recºr- Diamond and Gold Jewelry, Watches for Ladies and Gentlemen, Sterling Silver Tableware, Bronzes, Antique and Modern; Marble and Bronze Clocks. Marble Statuary, FAN cºr Coons, G E N E R A L L Y. O D O E& L E S S A N ID PA I, A T A E L E • * In calling the attention of Physicians and Druggists to the Cod Liver Oil manufactured by Messrs. MARVIN BROTHERs & BARTLETT, of Portsmouth, N. H., (of which we are the sole wholesale agents in the United States, we can confidently assert that this article has merits which should gain it the preference over any other Oil in the market. Our notice was first attracted to this Oil by several leading physicians of the city, who had found that it was not only well borne by invalids who had been unable to take that supplied from other sources, but that its use was attended with such advantage as to prove its activity and efficiency. Careful testing with chemical reagents, and examination of the sensible properties of taste and smell, convinced us that the claims of this Oil were well founded. In order to secure the best medicinal effects, Cod Liver Oil should be derived from the pet- fectly fresh livers, and at such a temperature that certain principles contained in it should not be volatilized. Thus prepared, the article is not a mere fuel or fattening agent, but also an alterative of much value, as is attested by its beneficial influence in Scrofula, in Rachitic Affections, in Chronic Rheumatism, &c. The inferior Oils which abound in the market are some of them prepared from livers partially decomposed, or by means of a degree of heat which drives off the iodine, bromine, &c., which the oil naturally contains ; others are made up in greater or less proportion of the oil from the livers of lower priced fish. In either case the article is rendered not only less tolerable in the stomach, but less valuable as a remedial agent. We believe the leading druggists have always endeavored to furnish their customers with as good an oil as possible, but hitherto they have been unable to secure a uniform quality, so that from time to time complaints have been made to all apothecaries, either of disagreeable taste or smell, or that the medicinal effects obtained have disappointed the expectations of the prescribers. We are now, however, confident that we can offer Marvin’s Oil as a reliable preparation for use in every case where an article of this kind is needed; and that the more extensively its merits are tested by the medical profession the more highly will they be appreciated. The Messrs. MARVIN, in order to devote their personal attention exclusively to the manufac- ture of the Oil, have retired altogether from its sale, which is in our hands only. JOHN WYETH & BROTHER, 1412 Walnut Street, Philadelphia. DIVIDED MEDICINES, (*REPARED BY The Divided Medicine Comy, CINCINNATI, OHIO. The Company have the honor of bringing to the notice of the Profession, this NEW AND ExCEEDINGLY PRAUTICAL METHOD of dividing into doses Medicinal and especially Narcotic Agencies, and recommending the same likewise to the consideration of Managers of Hospitals, Boards of Health, and the Public in general. The Divided Medicines are prepared by FREDERICK KRAUs, Chemist of the Company, with the most scrupulous accuracy, according to the rules of Pharmaćy, in conformity with the latest improvements and discoveries in Chemistry, and in such a manner that the several SQUARES must of necessity contain just the exact quantity of the PREPARATE in question, as indicated on the envelope, and NO MORE. The Divided Medicines, being prepared by the fluid process and afterwards effused into mathematically accurate square forms, it must be obvious, every drop of the solution necessarily containing an equal quantity of the medicament, that in the solidified mass every square will consequently contain accurately measured quantities. But not only SolubLE, but also INSOLUBLE MEDICAMENTS, we are able by this process to reduce in most accurate \ division into the form of DividLD MEDICINES. ū; * This PATENTED METHOD of preparing Divided Medicines enables us to produce squares, each containing 1 grain, ; : *, *, *, and even lobo part of a grain, and, if so ordered, even less quantities, which accurate division could not be effected by the dry process of preparing medicines. & Besides the peculiarity of THESE MEDICINES, that they are NOT LIABLE TO SPOIL BY ANY LENGTH of TIME they may be preserved, they recommend themselves to Physicians: first, because they may be administered instanter when ordered; and, second, because they are perfectly reliable in their efficacy on account of their accurate preparation. At the same time, the Divided Medicines claim this superiority over otherwise prepared medicines, that they may be administered to the tender babe as well as to the decrepid old man, in an easy and agreeable manner, it being simply necessary to put into a tablespoonful of water and swallow down, without experiencing any disagreeable taste. Gentlemen of the profession, practicing in the country, will welcome these medicines gratefully, as being easily transportable, enabling the Physician to furnish the sick directly at their professional calls with good accurately dosed medicines; and that these medicines have the Superiority of being cheaper than any others, as seen by the schedule of prices. Should any gentleman of the Profession wish to get these Divided Medicines, according to his own prescriptions, stating accurately weight and doses to one of our agents, or send the same, as below, he will receive the medicines in any number desired, (though not below one hundred squares,) within four days. For samples, Price Lists, and Agencies, address The Divided Medicine Coe IECX 2688, f Or FRFDERICK KRAUS, Chemist and Druggist, Walnut Hills, Čincinnati, O. Q MR. FREDERYCK KRAUs: CINCINNAT1, February 15, 1871. Dear Sir—The specimens of your “Divided Medicines,” handed to me for analysis, I have carefully examined, and would report, that I find all the specimens to contain the substance they are said to contain, in the quantity specified in each, viz: SUI, PH:MORPH II....................... % grain in each square. ARSEN: A CID.......................... 1-20 grain in each square. “ CH IN INI ....................... 1 § { { { {* CALOMEL.............................. 34 “ sé {{ * COPPER ........................}% $6 RESPECTFULLY YOURs, E. S. WAYNE, Analytic Chemist. T H H C T , T NT I. C. 301 Vol. 2.] S A T U R D A Y, J U N E 20, 1872. [No. 26, Q R. I.G IN A L A R T I C L E S. MHI E R N H A C E R E E R iſ e BY P. S. CoNNER, M. D. prof. Surgical Anatomy in the Medical College of Ohio. Read before the Ohio State Medical Society, June 12, 1872. Nearly half a century ago Baron Larrey declared that “a large hernia cerebri is one of the most serious acci- dents accompanying wounds of the head, and it is sel- dom that individuals so affected recover.” Why thisis so is a question that has much engaged professional attention, its consideration of course involving that of the associated question of the nature of the protrusion. When and under what circumstances is it developed ? There must be a preliminary loss of substance of the cranium. In the vast majority of cases this loss of substance is the result of fracture or the application of the trephine, but that it is not necessarily so is proved by such cases as Caesar Hawkins' and Pearson's, in which there was loss by progressive thinning in the one and extensive necrosis in the other, both patients being syphilitic. The loss of any extensive portion of the cranial vault, even to 7x5 inches as in the case reported by Kinkaid, of Ireland, (Dub, Quart. Journ., Feb., 1869,) is by no means necessarily followed by hermial protrusion; indeed such a hernia need not be so much expected under these cir- cumstances as when the opening is Smaller. Reported cases have proved that Guthrie was not so far away from the truth as has been by Some supposed, in saying that “these protrusions rarely take place when a considerable portion of the skull has been lost or re- moved.” Generally the separation of these large pieces of the bony covering of the brain is a slow process and the result of necrosis, under which circumstances hernia cerebri is not likely to occur, be the opening large or small. Again, not only must the bony wall be defec- g tive, but generally the dura mater has been lacerated at the time of the injury or operation; yet the integrity of this membrane under such circumstances does not necessarily forbid the development of the protrusion, for in consequence of pressure from below the membrane may be pushed outwards and became gangrenous, or as in the famous case reported in the Edinburg Medical Es- says, torn by the violent impulse of the cerebral mass against it, strengthened though it was by cicatricial tissue of seven months standing. Age seem to have some influence in the production of the hernia ; certainly a decidedly greater number of cases occur in patients under the age of puberty than is proportionate to the relative frequency of lesions of the head before and after that period, Facts, however, do not warrant so sweeping an assertion as that of John Bell, who declared that “whenever it is necessary to make large openings in the cranium of boys, protrusion of the brain and death ensue.” It is very doubtful if sex has any influence upon the lesion in question. It is true that the great majority of cases are in males, but the same is true also of the relative frequency of the injuries and operations which are likely to be followed by the hernia. At what time in the progress of the case does the protrusion occur ! It has been said that in some cases the hernia manifested itself immediately after the receipt of the injury. Using the term hernia in its usual sense, to wit, the abnormal protrusion of a viscus or part thereof from the cavity in which it is normally contained, a hernia of the brain may certainly occur at such a time, but this differs widely from what is techni- cally known as hernia or fungus cerebri. This last may appear as early as the third day or as late as in the fourth month, but in the majority of cases it shows itself in the latter part of the first or during the second week. Its appearance and development may or may not be attended with symptoms of cerebral disturbance. Very generally the characteristic phenomena of inflammation of the brain substance or the meninges, or both, appear sooner or later, and death is preceeded by coma of longer or shorter duration. In one of the fatal cases under my care, it was not until the 21st day that headache became a prominent symptom, and not until the 23rd day, 16 hours before death, that convulsions occurred, followed by coma, What is the nature of this protrusion, slowly or rapidly rising up through any abnormal cranial opening ; pulsating synchronously with the heart ; in some cases spontaneously subsiding ; in others falling back after sloughing or removal or removals of protruding por- tions; in yet others growing mushroom-like all the faster the more it is meddled with ; always, even when very small, a source of much anxiety, and throwing grave doubts over the prognosis; in a large majority of cases the complication of fractures of the skull that leads the surgeon to say to himself, if not to others, “this case will certainly prove fatal.” In the various writings on the subject there have been described as cases of hernia cerebri, luxuriant granula- tions from the unbroken dura mater, blood clots, gran- ulations arising from the injured brain substance, and protrusions of cerebral matter more or less altered from the state of health. We may leave out of consideration exuberant granulations arising from the edges of the wound and the dura mater at its base; for these, though not uncommon, are of no special severity nor danger, and should not be regarded nor described, as herniae cerebri. Blood-clot tumors, again, need not detain us. 302 [JUNE 29, 1872. T EHI E CIT, IISTIC. We may find such very early, when they are the results of primary hamorrhage, or later, when the blood is poured out from small vessels opened by the inflammatory pro- cesses going on in the part. It is very questionable if such clots can become organized, and any enlargment of these clot-tumors must if real be in consequence of renewed bleeding, or be apparent only, the increase of protrusion being due to pressure from below. The two remaining forms of the protrusion may be considered together, By some it has been contended that there is not in any case a true pushing-out of the brain-substance, but few as are the records of careful microscopic examinations of portions of removed herniae yet there are among these, reports of the finding of unmistakable evidences of the cerebral nature of the tumors, Again, if no brain substance is present, how are we to understand such cases as that related by Spring, where after successive growths and removals, running through a period of eleven years, autopsy showed complete absence of the left hemisphere, For a long time the opinion was held that the tumor was the result of the increased blood supply or the part, the overfilled portion of the brain pushing out where it met with least resistance, and by such pushing out, in many cases, relieving the individual affected from the evils that would otherwise have arisen from abnormal pres- Sū Pe. Again it has been held, as by Sedillot, that the pro- trusion is due to pressure from within from intraven- tricular dropsy ; thus associating the disease under consideration with congenital encephalocele. In some cases at least this pressure is undoubtedly the cause, for post-mortem examinations have shown a distended ventricle with softened walls, and before death for many days sometimes there is a continual flow from the hernia of a thin fluid in considerable amount, as I have myself observed in one case.* As to how this ventricular dropsy takes place we are of the opinion that they are correct who maintain its dependence upon, most generally, inflammation of the pia mater, Any traumatic inflammation of this membrane spreads rapidly from the place of injury over the whole side of the head, and through the connection of the basilar pia mater with the choroid plexus there is little difficulty in understanding how secondary intraventricular inflam- mation and effusion may occur. In Some cases doubtless an inflammation of the lining membrane of the lateral ventricle and of the choroid plexus is developed by con tiguity from the local inflammation of the injured por- tion of the brain, and this inflammation thus excited will be followed by intraventricular effusion. The true nature of the hernia is, I believe, expressed by Wilks who says, “after fracture of the skull and injury or sloughing of the dura mater an inflammatory exudation takes place and this mixed with the softened oerebral * Lowe attempted to explain these watery discharges by declaring that the fluid was the natural Secretion of brain granulations as pus is of granulations in other parts. substance protrudes from the surface; if cut off it is found to be composed of brain and inflammatory products.” That such inflammation should be developed is most natural. The cerebral substance has been more or less contused and lacerated at the time of the injury, perhaps of the operation; the parts either directly or covered by the meninges are exposed to the air and thus excited to inflame; and in not a few cases spiculae of bone are driven deep down into the brain, and escape detection and removal. Are not these, one or all, sufficient to develope acute encephalitis and meningitis, which latter, if not primary, “almost constantly coincides with superficial inflammation of the convolutions?” What are the pathological changes that take place in the course of inflammation of the cerebral substance? Says M. Laugier, the author of the article on Encepha- litis, in the 13th vol. of the Nouveau Dictionnaire; “thanks to Hayem's researches it is well known that the inflammatory process presents in nervous tissue the same characters as in other tissues, AS in all vascular parts, proliferation of cellular elements, hypergemia and the formation of an exudate constitute the essential elements. It may terminate in hyperplasia or suppura- tion, probably also in resolution, perhaps in gangrene. “There is,” says the same author, “oedema and con- gestion in parts around the inflammation-centre, and serous effusion into the ventricles.” Jaccoud says; “Vascular exosmosis follows the initial fluxion, and a serous or sero-fibrinous exudation is poured out into the tissue, which separates its elements and produces the rapid early softening which characterizes encephalitis, Most ordinarily the exudation presents itself in the form of an albuminous mass, finely granular, diffused between the nerve elements and mingled with Small flakes of coagulated fibrine.” Numerous post-mortem examinations in cases of hernia cerebri have revealed just such a condition of the protrusion and parts around as would be produced by an inflammation presenting the characteristics above given, I have myself found the posterior lobe of the right hemisphere very extensively softened, even diffluent, so much so that the posterior cornu of the lateral ventricle could not be traced; the cortical sub- stance of the middle lobe of dark color, shading off through an olive-green to the normal color seen in the anterior lobe. All the ventricles had been much dis- tended, and their walls were softened. But slight evidences were present of meningeal inflammation. In a number of cases, a number too great to admit of the theory of accidental association, cerebral abscesses have been found to exist below the hernial protrusions. Microscopic examinations of specimens from cases of acute encephalitis, according to Jaccoud, show “with the exudate the following elements; red corpuscles, leucocytes granular or not, debris of fibres’ or nerve- cells, masses of granulations, free nuclei, finally, fatty granules coming either from the nerve-elements them- selves, or the cells of the neuroglia which very probably , JUNE 29, 1872.] T IEEI IE C T , T INT I C . 303 are first attacked by inflammatory hypernutrition.” Similar examinations of removed portions of hermial tumors have shown with portions of tubules and cells, broken down nerve-fibres and cells, free nuclei, blood corpuscles and granular matter. The argument in favor of the inflammatory origin of hernia cerebri is further strengthened by the fact already stated that the protrusions are most common in early life, the period in which acute inflammations of the brain and its coverings are most frequent and run highest and yet further, by the fact of their comparatively sel- dom occurrence in cases of necrosis of the cranial bones; cases in which chronic inflammation has been long pres- ent and in which acute encephalitis or meningitis is very rarely developed, If then cerebral and meningeal inflammation is the cause of hernia cerebri, and if it is not the protrusion and loss of brain-substance that kills, but this causative inflammation, the indications of treatment are plain ; viz., to remove all irritating causes as far as possible, and moderate the inflammation by appropriate general treatment. All cauterizing, excising, ligating, violently compressing the protrusion must do harm, Maintaining, cleanliness and slight pressure upon the tumor, and so far as practicable excluding the air, are all the local measures of treatment that it seems to me should be adopted, I have myself applied nitrate of silver and acetic acid, have made firm compression by adhesive straps and lead plates, have used the knife, scissors and the ligature, but shall hereafter hesitate a long while before I repeat such treatment. If the inflammation does not run so high as to bring about a fatal result, it will after a time subside, and with its decrease will come a spontaneous gradual reduction of the hernia, -—º-o-º- C E R E E R O S P IN A I. -N.I E N IN G IT I S. BY J. R. BLACK, M. D. Columbus, Ohio, As cerebro-spinal meningitis appears to be prevailing more or less over the country, the following case may prove instructive: W. H. B., twenty-five years old, by occupation a machinist, was seized April 25, with what appeared to be a remittent form of fever. On the 26th, however, the symptoms of concentrated disease in the head, assum- ed a prominence which I hoped was mainly due to sympathy with a deranged stomach. A thorough action of a cathartic on the ensuing night did not give the relief to the cephalic symptoms that I had hoped. The pain persisted in the head, often of a severe lancinating character. The face was flushed, the eyes slightly in- jected, the skin moist, temperature nearly normal, the pulse 82, but fuller and rather harder than natural. The thirst was considerably increased, the tongue moist and lightly furred. The mind was clear, though evi- dently oppressed, and every now and then he said he was chilly. As he had not slept for 48 hours and the indications all pointed to inflammation of the cerebral membranes, I ordered bromide of potassium 15 grs., every hour, to be continued until case and sleep were procured, April 27. The morning report was, that the medicine seemed to make him worse and more restless; he had no sleep, but moaned and tossed with pain in the head the night through. The pain shot from the forehead to the back of the head every few minutes; and I noticed that the head was decidedly retracted. By my invita- tion, Dr. Spencer saw the case with me, and concurred in the diagnosis of cerebro-spinal meningitis. As the bromide seemed to be indicated on the physiological property claimed for it, of diminishing the quantity of the circulation in the brain, I determined to continue it, and at the same time administer small doses of morphine ; hoping that any exciting effect of the latter would be guarded by the former. The effect not being all I desired, or but partially quieting, I determined in the evening as the patient was of a full habit to bleed; which I did from the arm to the amount of a quart. This to be followed with morphine one-fourth of a grain and calomel half a grain every two hours until pain is relieved and sleep procured. April 29. Slept well, feels very much better, not so much retraction of the head, in short all the symp- toms, Save that shown by the tongue which was very dry, were better. This treatment by morphine was continued for a week with occasional cathartics, until the disease was entirely subdued. His recovery was slow but complete. Though this was by no means a rapid and malignant case; such as it was my fortune to see in 1864; yet the character of the disease was unmistakable. In some respects it is more instructive than the fulminant form to which I have referred; for here the course of the disease is so rapidly fatal that it is diffcult to discern what treatment is beneficial and what is not. The good effects of depletion and opium were very decided; although the former was practiced at a period in the case somewhat late, yet, as the result proved, not too late. Of course venesection to be beneficial in the fulminant form should be resorted to at a much earlier period of the disease. —-º-º-º---— A BUST of DELPECH.-The city of Toulouse renders homage to one of its most illustrious sons, by the in- auguration, May 1, of a bust to the distinguished surgeon, Delpech, which was placed in the capital among the celebrities of France. The inauguration oration was delivered by Prof. Bonisson, one of his former pupils. 304 [JUNE 29, 1872. TIEEE THE C T , T N T C . E L E C T R O T H E R A P Y. CoIIected from Various Sour|rces. From Schmidt’s Jahrbücher, April 18, 1872. Electrolysis and Galvano-cautery (Hedinger, Würtemburg), For electrolysis the batteries to be recommended are those of Daniell, Stöhrer and Pineus in the entire strength of their construction. A chief consideration is this, that the needle from the negative pole only be introduced into the tumor, the positive to be placed upon the skin in its vicinity. To avoid pain, which is only experienced at the beginning of electrolysis, the current is to be gradually strengthened. The duration of sessions must not be less than } of an hour, may ex- tend to $ an hour. The stronger the current, the more marked is its effect in shrinkening the tumor; to a speedy effect contribute also the softness and blood- vessel richness of the tissue. - The author himself has had but limited experience in this way. His cases were 8truma, eaco8tosis, lipoma, adenoma, myxoma, and several cases of complete opacity of the membrana tympani. The tumors were partly re- solved, partly, at least, essentially reduced. The cases of opacity so far improved that the handle and drum contents became visible. For galvano-cautery the author recommends the bat- tery of Groves; for cauterisations of short duration the new battery of Bunsen with bichromate of potash and dilute sulphuric acid is also appropriate. Individual experience in this field the author has only had in otology. He used the instrument of Jacoby for ablation of the polyp. This ablation can only be prac- tised in cases where the polyp, whose pedicle is not broad, springs from Some base other than the promontory. Else, the linear or punctated cauterisation must be adopted and repeated, according to necessity, until final resolution. The chief advantage of this treatment in these cases consists in the fact that the remains of the tumor becomes covered with a thick Secreting membrane, hence the consequences of suppuration are avoided. On several occasions, the author had the opportunity of observing the development of a new membrana tym- pani from the remains of the tumor, of cicatricial tissue. Galvano-caustic perforation of the membrane has no advantage over the usual method. Tinnitus aurium was treated on the plan of Brenner and when it was uncomplicated, as by catarrh of the middle ear, the influence was favorable. Improvement occurred in a case of one-sided paralysis of the acoustics in consequence of atmospheric pressure. Congenital deafness was not affected. Several cases of neuralgia trigem. and occip. were cured as were also several of joint stiffness and muscle paralysis after gun-shot wounds. --- Dr. Ludwig Seeter (Vienna) reports three-cases of resolved tumors which are not without interest. The first case was that of a young woman attacked in the puerperaſ bed with left sided abdominal pains pro- duced by a hard tumor which gradually extended to oc- cupy almost the whole left lower half of the abdomen up to the umbilicus. This tumor induced cramp in the hip and knee joints which, with subsequent oedema of the lower extremities and abdomen and albuminuria, reduced the patient to the last degree. All treatment both internal and external had been futile. After a duration of six months, the electrical treatment began. The positive pole was placed in the lumbar region, the negative over the hypogastrium and the current was gradually increased from 8-12 elements. Improvement both local and general commenced after a few sessions, and in 33 months cure was perfect. The second case was that of a considerable swelling of the glands of the right groin and vicinity as sequelae of Scarlatina, in a young person. After two months this Swelling presented as a dense, flat, exceedingly painful tumor, which gradually increasing in size occupied the whole space between the quadriceps cruris and adduc- tors extending down to the middle of the thigh, render- ing passive as well as active motion of the hip impossi- ble. The application of the constant current was made exactly as before. Improvement rapidly manifested, and in 29 session (6 weeks) a perfectly normal condition of the parts was established. The third case was an inflammatory affection of the right iliac fossa incident to puerperium with great pain and tenderness and contraction of the hip-joint, but without demonstrable tumor in the abdomen. After two months duration the electrical treatment was commenced as above described and after 23 sessions (one month) the patient was cured. Encouraging results were obtained also by the same method of treatment in cases of exudation in the lungs and pleurae but no detailed statements are given, * Bysteria—Catalepsy. Dr. v. Holst (Riega) reports atypical case of catalepsy in a hysterical girl aged 17, with flexibilitas cerea of the whole body including the muscles of mastication, perfect anaesthesia of the skin and muscles, total loss of consciousness except necessity of drink and urination, superficial respiration of 20, pulse 80–100, temperature 30–30.5° R, and markedly diminished muscular reaction to Faradisation. As all other means of treatment had been without result, the author commenced galvaniza- tion of the spine on the fifth day of the disease. A descending current of 18–24 elements, Stöhrer's plate battery, was without effect; a current from 30 elements both ascending and descending, however, secured, during the whole time of application, an imme- diate relaxation of the body including, at first, the muscles of mastication, so that the patient, during galvanization could be easily fed. At the same time there was an increase in respiratory frequency to 40 and suffusion of the hitherto pale face. Under the continued application of this agent the patient gained ground steadily through relapses and re- newed attacks at longer intervals were not infrequent. At the end of four months, after daily sessions, sensibility and motion had become normal when suddenly a fourth JUNE 29, 1872.] TIEEE IEH C T , I INT I C . * 305 attack of catalepsy ensued and lasted 24 hours. After this the patient recovered entirely, Cutaneous Faradisa- tion was still being maintained at time of report. Tremor Mercurialis et Potatorum. Dr. Camille Chapot Duvert (Paris) has observed most- favorable effects in these affections by the use of the in- duction current in the form of electric baths. He uses the Bunsen's elements, medium size, primary current. The positive pole, connected with a large carbon end is put into the lower (foot) end of the bath, the negative, a zinc plate into the upper (head). The baths are to be taken daily, duration 20 minutes. The patients treated for mercurial tremor were mostly young persons: all recovered after 16-40 baths though the tremors had existed from 8 weeks to 12 months. The recovery was perfect and permanent. Only once was there any recurrence, and this yielded to 14 baths. With tremor, potatorum the author has treated but one case. This was marked, however, affecting all the ex- tremities. Seven electric baths cured it perfectly. Constipation. Cases of obstinate constipation cured by electricity are reported by Dr. A. Cade (Paris), and Dr. Löwy (Vienna). Cady reports a case of 40 days constipation, a sequel of former dysentery. The patient, a female of 80 years, was very near death when the treatment began. The author employed the increasing induction current, neg- ative pole in the anus, positive over the umbilicus. In ten minutes after the first session an operation ensued though this effect had not been gained by all other kinds, of therapy. In Löwy's case the constipation was clearly induced by the ingestion of an excess of grapes with the seeds. After the adoption of various means, when the patient was in collapse, having had stercoraceous vomiting, the induction current was applied, one pole in the anus, the other in the neighborhood of the pylorus. It was allowed to run in full intensity for 15 minutes. There- upon ensued a chill, stercoraceous vomiting and an alvine discharge, all to be repeated with a repetition of the Faradisation after several hours. On the next morning two applications were made, followed directly by fecal vomiting, and in two hours by the discharge of a hen’s-egg sized mass of grape seed. Another Faradisa- tion on the following day produced another discharge of seed; whereupon a tedious convalescence to perfect health. - —º-o-º- BordEAUx IN LIEU of STRASBOURG.—The Medical Times and Gazette states that M. Jules Simon, the Minister of Public Instruction in France, has accepted in principle the creation of a Faculty of Medicine at Bordeaux to replace that of Strasbourg, and that a com- mission has been appointed to report upon the project in question. It is also in contemplation to establish a School of Medicine and a School of Pharmacy at Lyons. A C A D E M Y O F MIE E M C H N E . * JAS, GRAHAM, M. D., PREST., L. WOLF, M. D., SECT, Transactions June 17, 1872. Reported by Joseph Ransohoff. Meningitis, DR, WHITTAKER called attention to a case which he had reported at a previous meeting. The patient, a girl 18 months old, presented all the symptoms of basilar meningitis, which had been diagnosticated, together with epilepti- form siezures which occurred at the same hour upon alternate days. Other members of the family suffering at this time from malarial fever, the convulsions were supposed to be of that origin, The child having been placed upon quinia, made apparently rapid strides towards convalescence, Within the last week, however, all the symptoms of basilar meningitis have again become manifest, and there is now no possibility of a recovery.* The Dr, then alluded to the fact that though meningitis often simulates intermittent fever in its fluctuations yet in this case he believed in the super- vention of the latter upon the former disease, or the co- existence of both. In this belief he is supported by the temporary effects of the quinia administered. DR. LUDLow remarked that he had been called to a patient nine years old, whom he found delirious and in convulsions, There was one peculiarity with regard to this case, that is, the child was semi-conscious while in a convulsion, this condition being manifested by the manner in which it followed a light held before its eyes. The case was treated as one of meningitis, by calomel and quinine internally, and by the application of leeches to the temples, and cold to the head and neck, Bronchial irritation supervening, the patient was placed upon a cough mixture, and is at present apparently re- covering from both diseases. . A DR. W. H. MUSSEY exhibited the cast of a stone which was sent to him by Dr. Jackson, of Boston, The cast measured 6 inches in its longest and 4} inches in its widest diameter. The patient from whom this was removed suffered from stricture of the urethra, and was in the habit of promoting a flow of urine by the intro- duction of a bottle into his rectum. This method being resorted to without relief, the sufferer introduced this stone into his rectum, which upon an attempt at its ex- pulsion probably caused a rupture of the intestine. The stone was afterwards removed from the peritoneal cavity by an incision made to the left of the umbilicus, and after its removal the patient made an excellent re- covery. × Died June 21, Post-mortem denied. 306 Tº EI IEEE C T I IN T C. [JUNE 29, 1872. The Dr. also presented a pathological specimen taken from a hen. It measured 5 inches in longest by 4 inches in its widest diameter. The tumor was, in all prob- ability, of ovarian origin. Uterine Fibroid. DR. T. WooD presented a specimen of this nature which he removed from a patient aged 35. She was in very good condition, and enjoyed excellent health, with the exception of the distressing inconvenience caused by the tumor, which had been growing for four years. It was a multiple uterine fibroid, one portion of the tumor extending to the umbilicus, while two other tumors were depressed in the pelvic excavation, thus pressing upwards the uterus and the bladder. This condition gave rise to very frequent and painful micturition, which suffering was, at the patient's express desire, the immediate cause of the operation. During the opera- tion the Dr. met with a peculiarity which he had never before observed. After making an incision through the abdominal wall, he came upon a membrane which greatly resembled the omentum, and which was covered by a very thick layer of adipose tissue. Supposing it to be omentum, an unsuccessful attempt was made to place it aside in order to make room for the removal of the tumor. An incision was then made through this membrane, which revealed the omentum in its proper position beneath. This layer was then nothing but one of cellulo-adipose tissue which had been formed between the peritoneum and the abdominal walls. After an in- cision through this tissue the tumor was removed to- gether with the greater portion of uterus, a portion of the cervix being left in the pelvic cavity. The ovaries and broad ligaments were also allowed to remain. The patient at the time of meeting was still alive. DR. REAMY who had witnessed the operation stated that it was a perfectly justifiable one since the patient would have succumbed under the exhaustion caused by so large a growth. He thought that the tumor was twice as large at the time of removal, its size having been reduced to this extent by its loss of blood. He remarked further that the pain in micturating was as constant as this act was frequent. He thought that this together with the rapid development of the tumor were causes sufficient in justification of the operation. DR. YoUNG remarked that there was one point of great interest connected with these cases of fibroid and cystic tumors. This point was the subject of a rule with Spencer Wells, who affirms that ovarian cysts descend into the pelvic excavation, while fibroid tumors rise into the abdominal cavity. This was a deviation from that rule. - DR. WooD stated that he placed very little reliance on this rule, since he has seen very many exceptions | to it. DR. DAWSON observed that this specimen differed from uterine tumors generally in its attachment, since a part of it was bound down by the broad ligaments, and since a portion of the tumor was depressed in the pelvic cavity. Although the chances are decidedly against the patient, the operation was perfectly justi- fiable. DR. MUSSEY remarked that he was treating a case of uterine fibroid with electricity. In this instance the tumor ean be felt in the pelvic excavation. It presses the uterus upwards, and it can readily be distinguished above the symphysis pubis. Before she came into the Dr.'s charge, she was suffering from very debilitating attacks of hemorrhage. Since the adoption of the treat- ment with electricity the patient has observed no recur- rence of the hemorrhage, and she has gained decidedly in health. In this case from 12–20 cups were used, the positive electrode being applied to the hypogastrium, and the negative pole (a button attached to an insulated wire) to the uterus itself. As to the tumor, it had been diminishing in size during the first few months, but for the last six months has been in statu quo. This partial removal of the fibroid tumor has been in accordance with the speaker’s observations which demonstrated that for a certain time there will be a reduction in the size under the use of electricity, but soon the latter seems to lose its effect upon the tumor. To this rule, but one exceptional case was found, namely, that of a large tumor in the right side, which came on after delivery. It extended from the lower border of the ribs to the crest of the ileum. In this case the electricity (from 15–20 cups) was employed by means of broad electrodes which were applied to the abdominal wall in the region of the growth. Under this treatment the tumor lost at least one-third of its original dimensions, and probably a farther diminution would have been obtained if the patient had not been several months pregnant. Under these conditions it was considered best to abstain from the use of electricity. Intra-uterine Medication. DR. REAMY presented to the Academy an instrument of his own invention for intra-uterine medication. With this he states that medicines of any character or strength in solution can be applied to any part of the uterine cavity with perfect facility, at the same time obviating all the objections to uterine injections. * As a full description of the instrument and its mode of application will be furnished our readers by the author, we refrain from any attempted description at present. * * On Motion the Academy stands adjourned over the holiday8. - —-sº-º-º- MEDro,AL NEws. º THE HAVANA MEDICAL STUDENTS who were im- prisoned and threatened with death for alleged desecra- tion of a cemetery, have been released by government orders. - JUNE 29, 1872.] TETH. cI.TISTI c. 307 PROF. W.M. WARREN GREENE, of the Bowdoin Med- ical College, Maine, has accepted the Chair of Principles and Practice of Surgery and Clinical Surgery in the Long Island College Hospital, Brooklyn, N. Y. DR. BENJAMIN HowARD, of New York, has accepted the appointment as Professor of Principles of Surgery, with Clinical Surgery and Diseases of the Genito-urinary Organs in the Medical Department of the University of Vermont, AN AMERICAN SURGEON DECORATED.—His Majesty the King of Sweden and Norway has bestowed, through the legation at Washington, upon Dr. Lewis A. Sayre, of New York, the knighthood of the Royal Order of the Wasa, “in acknowledgment of the services rendered by you to the study of medical science in Sweden.” This is accompanied by the letters patent and a most beautiful jeweled decoration, with Greek cross and crown, together with letters, couched in terms of friend- ship and admiration, from the King and the Royal Physician.-Phil. Times, June 15, '72. THE MUNICH JUBILEE.—On the first of August of this year the University of Munich celebrates its four hundredth anniversity. Representatives from all the universities of Germany and Austria are invited to be present. - 4. A MILLENIAL CELEBRATION.—The University of Oxford celebrates its one thousandth anniversary this SUIIA). O16Iſ, - STUDENTS AT STRASBOURG.—Up to May 27, 227 students had been registered at the new university of Strasbourg. THE PARIS FACULTY.—M. Béclard has been appointed Professor of Physiology, vice M. Longet, deceased; and M. Verneuil, Professor of Surgical Pathology, has been transferred to the Professorship of Clinical Surgery made vacant by the death of M. Laugier. DR. BROWN-SíquARD.—The recent announcement in our columns that Dr. Brown-Séquard would deliver a course of lectures before the Harvard Medical School the coming winter was premature. We learn that no arrangement has as yet been made for the course alluded to.—Bost. Med. Journ., June 20, 1872. JoB. JEFFERSON's EYES.—The operation for the re- lief of glaucoma which threatened a total blindness of this distinguished actor has resulted successfully in the hands of Dr. Reuling, of Baltimore. THE NIGHT WATCHES OF BERLIN.-During last month two sanitary night watches were opened in Berlin. Their location is marked by a red cross of gas lights for easy recognition. Each watch includes six physicians and three experienced nurses. Of these each alternate two physicians and one nurse stand guard every night, in the summer months from 10 P.M., to 5% A. M., in winter from 10 P.M., to 64 A. M. The interior of these places is so arranged that reception and assist- ance can be at once afforded in all cases of accident, and the patients are retained under medical supervision until they can be forwarded to their homes or to the hospitals, The paraphernalia of instruments and medicaments is of course complete. FEMALE MEDICAI, STUDENTS.–In St. Petersburg in consideration of the admission of females to the univer- sity of Helsingfors the following laws have been estab- lished: 1st, Females are admitted gratis to the lectures of the medical faculty, and in consideration of a sum to be hereafter established to the occupations of the labora- tory and the anatomical theatre. 2nd, Lectures shall be delivered in the Swedish language. 3rd, Females are required to bring certificates as to their former edu- cation and avocation. 4th, They are not allowed to omit any examination. At Zurich there are among the 200 medical students some 20 women. This session, 15 new applicants are registered; only five of these have as yet been accepted, as the rest have only been able to exhibit pass-ports in evidence of character. It is intended to be still more rigid, in this regard in future, as it is designed to limit this class of students.-Wien. Med. Presse, May 19, 1872. DEAD ON THE TABLE.—On May 27, a patient with osteo-myelitis was placed on the operating table at Vienna for enucleation at the hip-joint. Chloroform had been given, the femoral artery happily ligated, the Langenbeck incision made, when as Prof. Billroth, the operator, was busied with scraping off the periosteum while in the act of Seizing the galvano-caustic noose to divide the soft parts, there was heard a gurgle and his patient was a corpse, Billroth performed tracheotomy at once but in vain, as were all the other means of re- suscitation undertaken. The operator had already stated that the case was one of extreme danger as the patient had been reduced to the last degree. He men- tioned further that this was the third operation of this kind during the day, and two of these had died under the knife.—Allgem. Wien. Med. Zeit., June 4, '72. BoAST NOT.-The late Mr. Lynn, an English surgeon cut twenty-five patients for stone without losing one. He them boasted that he had, at last, discovered the secret of performing lithotomy with success. Afterwards he declared that the Almighty punished him for his presumption, for he lost the next four patients that he cut.— Paciftic Med. and Surg. Journal. - It was rather a small business for the great God of the universe to kill four innocent afflicted men to dampen the feathers of a self-conceited egotistical surgical ass. This combination of egotism and blasphemy is a bow- shot beyond anything we have ever seen in print, or out of it. His last boast was greater than his first, Pun- ished him by killing four other men l l l—Sr. Ed. Nash- ville Jour. Medicine and Surgery, June, ’72. 308 [JUNE 29, 1872. T IEEE TEH C T , T: INTI C. REVIEWS. A TREATISE ON THE DISEASEs. OF INFANCY AND CHILDHooD. By J. Lewis Smith, M. D., New York. Published by H. C. Lea, Philadelphia. For sale by Robert Clarke & Co., Cincinnati, Ohio. Price $6.00, Cloth $5.00. It gives us pleasure to notice the publication of the second edition of this valuable work. It comes to us revised and enlarged, a handsome octavo containing 740 pages. To the making of books there is no end, but good books are limited. The ease and rapidity with which books are ordinarily written, to the uninitiated is some- thing wonderful. It has been said, and with a great deal of truth, that all that is necessary for the production of a book is that the ambitious and learned writer should surround himself with the literature of his subject and then proceed to compile. If he does his work well we have a useful book. We are far from despising such productions and extend our hearty thanks to workers of this class. But our libraries are overrun with such books, and it is difficult to read much in medicine with- out being impressed with the idea that what is said has been said. But the book before us is not a compilation. While the writer has made free use of other authors in bringing his book up to the present status of his department of medicine, he advances his own ideas with the freedom of a man that has had clinical experience. We think the author has done well what he endeavored to do. We quote from his preface “he has endeavored to incor- porate in the treatise all recently ascertained facts re- lating to this branch of practice, and especially to rec- ommend such modes of treatment as comport with and are suggested by our present knowledge of the pathology of early life, the efficacy of hygienic measures in the treatment of the young and the recuperative powers of the system. * * As a result of independent investi- gation, opinions are now and then expressed different from those commonly accepted. Novel views, however, have not been presented, unless the author was fully satisfied that they were substantiated by a sufficient number of observations.” We know of no book on this subject that we can more cordially recommend to the medical student and the practitioner. THE URINE AND ITS DERANGEMENTs with the Ap- plication of Physiological Chemistry to the Diagnosis and Treatment of Constitutional as well as Local Dis- eases; being a course of original lectures delivered at University College, London, by George Harley, M. D., F. R. S., F. R. C. P., Corr. Member various medical, etc., societies, former Prof. Univ. Coll., and Physician to Univ. Coll. Hospital, with illustrations. Philadelphia, Lindsay and Blackiston, 1872. For sale by Robert Clarke & Co. Price, $2.75. These lectures were originally delivered as stated, and afterwards published at intervals in the Medical Times and Gazette. Two of them ouly Diabetes and Albumi- nuria were subsequently reproduced separately. Notwithstanding its confessed importance it is a question whether there is a department in medicine that becomes more distasteful to the general practitioner than that of urinalysis. The young practitioner com- mences by eagerly testing every specimen upon which he can lay his hands. But the novelty soon wears off; he soon tires of toying with his tubes and the time comes when it is absolutely irksome to examine a case when there is even more than a suspicion of kidney disease. The older practitioner can hardly be hired to touch it, he turns the specimen over to the chemist, if at all conscientious, or, if not—and such, too, there are—he turns over the specimen which he has so solicitously obtained to the spontaneous processes of decomposition and “goes in on general principles.” .* Why is this the case? We do not stop to discuss the reasons which actuate the last category. This con- stitutes the great class of ‘regular' quacks who can write 75 prescriptions before breakfast without making a single diagnosis, who sleep with the snore of the unctiously pious and who die and are canonized in the good course of time after having blocked the path of honor and usefulness throughout the whole course of their indolent lives, Urinalysis is distasteful to many conscientious physi- cians for two reasons. One is because this field is usurped to such extent by the most unscrupulous pretenders that the honest physician almost fears to enter it. The other, and the main reason is the time and the labor prerequisite to obtaining the necessary knowledge and skill. The first is really no objection at all or at least is only common to every means of diagnosis and treatment in our possession. We may quote, indeed, in this regard from the work upon the table. “It is true that uroscopic charlatanism has, more or less, in all ages, laid human credulity under contribution and thereby brought discredit upon, and retarded the advance of legitimate science; but this must not deter the honest practitioner from reaping the advantages which a knowledge of this secretion affords.” The second objection may easily be obviated by the study—it is so pleasantly written it may be studied by simple perusal—of just the very book under review. It is really wonderful how interest kindles into pleasure —that pleasure which surpasses all other, the pleasure of the acquisition of knowledge—as its pages are rapidly turned. We cannot give in the short notice which our space affords even a synopsis of its contents. We may state only that the work is systematically arranged in its full and thorough description of the various ingredients of the physiological and pathological Secretion and that the chapters on diabetes and albuminuria (including puerperal) occupy full one-third of the volume. Two golden sentiments we encounter as we hastily JUNE 29, 1872.] TIEEE THE CIT, TINT I. C. 309 review its pages and we reproduce them here in evidence of the spirit of its author, best of evidence, too, of the value of his work. “In fact until within the last year or two men have been constantly attempting to place, as it were, the pyramid of medical science on its apex instead of on its base, and the result has naturally been that they reaped little benefit from their labors. It seems, indeed, as if they were only now becoming alive to the all-important fact that Physiology is the only true basis of Rational Medicine and that in direct proportion as they adopt its principles will be the success of their labors in ad- vancing the healing art. Such being the views now held by the pioneers of Clinical Medicine in all coun- tries, you will readily understand why, before entering in the pathology of urine, I first try to give you a succumct account of its physiology.” And here is the other. “When I hear men saying that the medicines they are employing are little better than useless, *t often occurs to me that they are, perhaps, not far from wrong, although the want of success may not be, as they “vainly' imagine, due to the impotence of remedies, but to the want of knowledge and judgment brought to bear on the employment of them. A man needs only to pay a little attention to the teachings of physiology to learn what powerful weapons nature has put into his hands. Like all weapons, however, they may be turned to good or to evil account, according to the knowledge or the in- clination of their employer. I would even venture to suggest to our skeptical brethren that it would, perhaps, be wiser if, before passing judgment on any particular remedy, they first made themselves familiar with the how, when and why to employ it.” It is really a matter of regret that we may not give a synopsis of the author's views on the treatment of albu- minuria and Bright's disease, but space compels us to leave the richer treat to the reader of enjoying it in ex- tenso in the author's better words. It is sufficient for us to say that in our humble opinion, the book covers its title. In typography, etc., need it be stated, the book is faultless. MINUTES OF THE 23RD ANNUAL MEETING OF THE AMER. MED. Association, Philadelphia, 1872, Price, 50 cents. The minutes include a full report of the transactions with lists of delegates, announcements of committees, etc. Two faults we have to find with these minutes; 1st, that they are not published in time to put one in the hands of each delegate before he leaves the place of meeting. See what lessons the politicians teach us in this regard. 2nd, that they do not contain full reports, at least abstracts, of the work of the special committees. But we are not blinded by these two defects to the gen- eral excellence of the minutes so far as concerns secre- taryship or typography, CLINICAL MEMORNADA. EXTRACTION OF FISH-Hook FROM OESOPHAGUS.– Dr. D. Cunningham of Wurtemburg, sends us the de- tails of a case of accidental lodgement in the throat of a fish-hook which he succeeded in removing by a very ingenious device. - “Every attempt on the part of the boy to detach the hook by drawing on the line which protruded from the mouth only imbedded it more deeply. As I could not reach it nor see it, I took a pistol ball, hammered it out flat and bored a hole through its centre. I then inserted the line through the orifice of perforation and pushed the ball down over the hook with a gum elastic catheter The point of the hook became imbedded in the lead when it was easily withdrawn.” AGENESIS OCULORUM.—Dr. Parsons of Carbondale, Illinois, sends a report of a case of congenital absence of both eyeballs. The palpebral openings are extremely small, the free edges of the lids being furnished with cilia. No trace of globes, only a smooth cavity lined with the conjunctiva which was affected with inflammation, against which the Doctor used injections of tannic acid, bromide of ammonium and rose water. The child in other respects is perfectly formed and is growing well. It was born early in May, '72; the fourth child of a woman of 25. An absence of these important organs is not so unusual. Dr. Strowbridge, of Philadelphia, (see the Ophthalmo- logical Trans, of 1871,) reports three cases. In one of these cases, there was absence of one eyeball, with a large colaboma of the iris and choroid in the other. INOCULATION OF SMALL-POX BY SKIN-GRAFTING.— In a recent discussion on skin-grafting in the Berlin Medical Society, Herren Hahn and Zülzer referred to an instance recorded in the Deutsche Militair-arztlich. Zeitschrift, in which portions of skin for grafting were taken from the amputated limb of a woman in whom, the day after the operation, the eruption of small-pox appeared, and proved fatal. One of the four patients on whom the skin was grafted had small-pox, but in a mild form. He was, however, a man of intemperate habits, and died, according to Herr Zülzer, of pneu- monia. VESICANTS IN EAR DISEASE,-According to Dr. Gruber, of Vienna, vesicants are useful, 1st, to cure sub- acute and chronic inflammatory processes in the ex- ternal auditory meatus. 2nd, to abate pains that do not yield to narcosis, Vesicants are suitable only when the inflammation originates in the bony canal, as they are either injurious or unnecessary when the inflammation is in the cartilaginous portion. The author advises that they be placed not on the mastoid process, but under it.—Allg. Wien. Zig- Arch. f. 0. 310 [JUNE 29, 1872. T EEL HD CT, ITNTI C. CAMPHOR IN PHAGEDAENIC CHANCRES.—By Dr. Henri Gafé.-These remarks, based on thirteen clinical observations, close with the following conclusions: In all cases where camphor has been employed the re- sult has been favorable, as is proven by the facts brought forward by MM. Cochard, Bandoin, Viguard. A modi- fication of the ulcer has been brought about promptly, within eight days. The longest period which we have observed was eight, the shortest two days. M. Bandoin observes in an average of five days a very satisfactory change. - As is well known the duration of a chancre of what- ever nature varies from five to eight weeks. We have observed a mean of one month ; some of them, it is true, are perfectly cured in 15-18 days. Surfaces of bad nature, like buboes of long duration, are perhaps less modified than chancres proper, but even they progress under this medication infinitely more favorably and quickly. The employment of camphor is exempt from pain. The powder is to a certain degree hemostatic, for we ob- served a cessation of hemorrhage a number of times after its application. It is likewise a potent disinfectant. In a case of excessively fetid cancerous ulcer the appli- cation of powdered camphor for three days sufficed to modify it considerably in both odor and aspect. But what is the best method of its application. As for ourselves, we have always employed the method of Netter, which consists in applying layer upon layer as fast as the lower layers liquefy, None is to be removed until treatment is ceased. This medication should be employed so long as the phagedaenic surface is covered by the pale pellicle characteristic of it. So soon as the surface becomes rosy and vivified, the pultaceous matter destroyed, camphor is useless. The best treatment then is a mild applica- tion. If the camphor be continued too long, it will necessitate the application of the nitrate of silver, when as much would be lost on the one hand as had been gained on the other.—Journ. de Méd. d. l'Ouest— Lyon Medicale, June 9, '72. GALVANISM IN DIABETES-An interesting applica- | tion of the constant galvanic current has been recently made by M. Lefort (Gazette Médicale de Paris, April 13) in a case of diabetes, He applied the positive pole to the back of the neck, and the negative pole to the hepatic region. The patient was in the habit of passing five or six quarts of highly- saccharine urine; but under the influence of the daily application of the constant current the quantity diminished to two quarts in twenty-four hours, and the proportion of sugar was about one-fourth of what it had been. The treatment, unfortunately, was interrupted at the end of a month, and nothing further is known of the history of the patient. Notwithstanding this, the amelioration of the symptoms produced by galvanism in this case affords ground for hope that it may have the power of curing diabetes.—Phil. Times, June 15, '72. TREATMENT OF TREMOR OF THE HAND.—-Dr. Cazenave (Bordeaux) has devised a most ingenious instrument [plate represented] to act as a support for the hand in those distressing cases of manual tremulousness. The support leaves the hand free in its movements so that the mechanism of writing can be performed with ease. In one of the number of cases narrated, a surgeon so far regained steadiness as to be able to operate with skill. In all the cases recovery was complete.—Gaz. Med. Paris. TAPPING AND STRAPPING OF HYDROCELE.—In regard, however, to hydrocele, it appears to me that we have in this plan of tapping and strapping one which satisfactorily fulfils the idea of curing safely, quickly, and pleasantly, and which, though perhaps not about to prove infallible, is one which should be certainly tried in all cases (especially, I would add, those treated away from the patient's home), before the injection of iodine or other stimulant is resorted to. If cases, occur in which neither the mode I here advocate nor the iodine treatment is successful, I am of opinion that a combina- tion of the two would be likely to prove so.-Bradley— Brit. Med. Journ., June 1, ’72. THE PROPERTIES OF THE PRINCIPLES OF OPIUM.– Note by M. Rabuteau, presented to the Paris Academy by Ch. Robin. My experiments, some 150, have been made on man in health and disease, on dogs, rabbits and frogs. I have studied the action not only of the six principal alcaloids of opium, but also of mecomic acid and meconine. These different substances have been at times ingested per stoma, at times injected hypodermically. The alcaloids of opium may be classed as follows ac- cording to their effects on man: Order Soporific: Morphine, narceine, codeine; the others do not induce sleep. Order Toxic : Morphine, codeine thebaine, papaverine, narceine, narcotine. Order Analgesic : papaverine, codeine. alleviate pain. Order Anexosmotic: Morphine, narceine. do not arrest diarrhea. Action when combined with chloroform or bromoform. It is known that the combined action of morphine and chloroform induces analgesia without of necessity pro- ducing sleep. A dog which had received 5 per cent. chlorohydrate of narceine under the skin, and was after wards anaesthetised by chloroform did not feel anything on awakening. He could be pinched, stuck, marched on his feet without evincing the least pain; yet he was able to walk, run even around the the laboratory. This extraordinary condition in which sensation was totally abolished, persisted for several hours. I have discovered that the same results, in different degrees, may be ob- tained with bromoform or chloral and any other alkaloid of opium except narcotine.—Gaz, Med. de Paris, May 4, 1872, Narceine, morphine, thebaine, Narcotine does not seem to The others JUNE 29, 1872.] T E-ITEI C T , T TNT T C . 311 THE TREATMENT OF ULCEROUS PARONYCHIA,-The occlusive method,according to the precepts of Chassaignac (covering the extremity with silk dressings), affords the greatest Service. It quiets pain, modifies the surface, favors cicatrisation. It is the treatment par excellence. M. Tourneur. has had excellent results with another method, as yet, but little known, viz., the application of the powder of iodoform. - In three most rebellious cases Diday obtained a cure by applying with care and perseverance a solution of nitrate of silver 1 grim, 20. It was applied on charpie which, thus saturated, was forced down in between the ulcerations to the bottom. In these three cases, ameli- oration commenced with the first applications and pro- gressed uninterruptedly, Cure was not complete, how- ever, until after 4–6 weeks,—Annales de Dermat. et de Syphil., No. 2, 3. '72.—Lyon Medicale, June 9, '72, ON SOME FURTHER ATTEMPTs To CURE LARGE IN- TERNAL ANEURISMS. By William Murray, M. D.— This was an account of some attempts to cure internal aneurisms by the insertion of foreign bodies with a view to the formation of clots in the interior of the sac. Some of these bodies were introduced and again withdrawn (needles), and their introduction was repeated at inter- vals with manifest thickening of the aneurismal walls on each occasion; others were of a material the presence of which would be as harmeless as possible (carbolized catgut), and they were used because of the hope that their absorption might take place after the work of co- agulation was completed. Lastly, wire was tried, as in Mr. Moore's case, and with more favorable results as regarded the preservation of the patient's life, he having laid more than three weeks with twenty-four feet of wire in him. Although none of these efforts were actu- ally successful in curing the patient, they marked out a line of practice which might some day be perfectly safe and successful.—Brit. Med. Journ., June 1, ’72. REMOVAL OF A HAIR-PIN FROM THE BLADDER OF A WOMAN.—Elizabeth Woods, aged 25, unmarried, a sewing-machine girl, admitted into the Melbourne Hospital, January 17th, 1872. Two days before her admission she had applied as an out-patient, stating that she had a hair-pin in her bladder. The vagina and the bladder were carefully examined, but no trace of any foreign body could be found. On the 17th she again applied, apparently in great pain. Another examina- tion was made, and the pin was then detected in the bladder. Her account is, that she had great difficulty in making water, and believing that there was some obstruction in her urethra, she attempted to clear it by passing one of her hair-pins up. By some means it slipped from her fingers and went into her bladder. She says she has often passed a hair-pin up her urethra. She was put under chloroform, and the urethra dilated by Weiss's dilator. On putting the fingers into the bladder, the hair-pin was found lying immediately behind the symphysis pubis. The two points were thrust through the mucous membrane of the bladder, the round end pointing downwards and backwards, being quite free. A pair of forceps was passed along the fingers, the round end was caught hold of, and the pin removed. On the following morning the patient stated that she was quite free from pain. She had perfect command of her blad- der, and there was not the slightest incontinence of urine from beginning to end. She was discharged well on the 25th.-Australian Medical Journal. - —-º-e-ºn- Trephinaing a Cerebral Abscess Surgeon J. T. Weeds, U. S. A., reports a case incident to gun-shot wound. The diagnosis was established and death was imminent. The operation is thus graphically described : “Made a crucial incision through the integument and sub-ligamental tissues to the bone, over the left frontal eminence, cut the supra-orbital branch of the left oph- thalmic and left anterior temporal arteries; closed them by torsion; bleeding stopped; applied the centerpin of Dr. Galt's conical screw trephine, at a point seven- eighths of an inch to the left of the mesial line, and an inch above the superciliary ridge. I selected this local- ity to avoid the falx cerebri and longitudinal sinus, to have uninjured bone to operate on, and it being the point over what I believed to be the position of the abscess. • - “A button of bone was removed without the least difficulty, but much to my mortification there lay, in contact with the calvarium, the dura-mater, in appar- ently a healthy condition, the coma as deep, and the respiration as embarrassed, as before the operation. What was to be done? Abandon the patient to certain and speedy death, and console myself with the belief that, having used the trephine, my duty was all per- formed? No, I felt satisfied my patient was dying from cerebral pressure, and I was equally well satisfied that pressure was produced by a cerebral abscess, and that abscess, I had already determined, lay beneath the left frontal eminence—the point I had selected for the operation. - “I proceeded to examine the wound and its surround- ings closely. Just to the left of the fenestra was a shallow groove, three-quarters of an inch long, made by the bullet; the bone seemed healthy; immediately on the side of the opening in the skull next to the mesial line, and beneath the groove, was a small delicate scale of bone flaked off the inner surface of the internal table, The dura-mater at this point, was slightly lacerated, but not inflamed, and seemed to be closely adherent to the skull. I thought it presented a bluish tinge I had never before observed, and it seemed to bulge up further into the fenestra than usual. I also imagined I could distinguish obscure fluctuation—I might be mistaken, it was so obscure—it might be only a fancy; yet I was convinced an abscess existed in close proximity to where 312 [JUNE 29, 1872. T TH. H. C. LI INTI C. the operation had been performed, and probably directly beneath the fenestra, I remembered how Roux, in a similar case, after trephining his patient, and even incis. ing the dura-mater, hesitated to extend the incision into the cerebral substance. Hispatient died, and an autopsy demonstrated that an incision, half an inch deep, through the external vesicular layer, would have reached and evacuated a large abscess. The celebrated cases of Du- puytren, Petit, Detmold, and Hawkins, flashed across my mind, and without further hesitation, my resolution was taken, I incised the dura-mater, and plunged my knife into the cerebral substance, My diagnosis Was correct—half an ounce of dark green and somewhat fetid pus flowed from the wound. Yet the coma and stertor continued, apparently not the least improved by the operation. “I cleansed and dressed the wound in the usual man- ner, put my patient to bed with head and shoulders ele- wated, applied a refrigerant mixture to the head, and waited anxiously for the result. The stertor gradually subsided; at 10 o'clock P. M. he moved easily; at mid- night he turned, and asked his attendant for water. “The subsequent treatment was simply expectant. Not a single unfavorable symptom supervened. The wound healed rapidly, and in two weeks my patient was walking about convalescent.”—Nashville Journal. SEA-SICKNESS,-As regards treatment, since sea-sick- ness arises from certain impressions on the senses, the obvious indication is to render these sensations as feeble as possible. Application of the mind to an engrossing book will keep it off for a short period; and Dr. Cham- bers relates that his having to bind up a broken finger of one of the seamen relieved his own distress for the time. But the mind will speedily become alive to the sensations which force themselves on its attention. In order to lessen them as much as possible, the patient should preserve the recumbent posture, as near the center of the ship as possible; he should lie on a thickly padded couch, so as to diminish the vibration. Fresh air should be admitted in order to remove bad smells. The eyes should be shaded, and as much noise as possi- ble shut out. As regards drugs, the most rational Sug- gestion is that of Dr. Döring, of Vienna, that a full dose of hydrate of chloral should be taken shortly before the vessel starts; and even in long voyages the repeated use of this medicine will ensure comfortable nights without the disagreeable after-effects of opium and chloroform.— Pollard–Brit. Med. Journ., June 8, '72. Double UTERUS.—Dr. Lloyd Roberts (Manchester Med. Soc., Apr. 3, '72.) showed an interesting specimen of double uterus and vagina, of the highest degree of division, taken from a young woman who died of epilepsy. She was also found to have only one kidney. AMPUTATION OF THE PENIS.—Mr. Westmorland (Manchester Med. Soc., Apr. 3, '72.) exhibited a penis weighing one pound and ten ounces, which he had amputated on account of venereal warts, To THE READERs or “THE CLINHC). * The close of the first half of the year ends the second volume of THE CLINIC, In the retrospect which we may now enjoy we experience in every sense that kind of satisfaction which is the legitimate reward of honest effort. It will scarcely be credited by those who are Somewhat familiar with the great expense of medical journals, that THE CLINIC in the short period of its ex- istence—not yet a year—and at the low price of its pub- lication—two dollars per annum—has already become self-sustaining. Yet it is absolutely true. This is of course partly owing to the increase in the number of advertisement pages, but is in the main due to the prompt enrollment of an army of subscribers. Thus much for the Sound condition of what the French call “the nerves of the war.” We have introduced this source of satisfaction first, not because we have deemed it greatest, but because in the maladies of medical maga- zines right here in the conducting nerves most frequently lies the pathogeny of the disease. As to the animating principle—to continue the simile —behind these nerves, THE CLINIC still has the same mission for the future as for the past. Our apostolic in- junction was and is to preach Medicine as a Science, to substitute for the fallacious fancies of experience the fixed facts of experimentation. It is in the conscious- ness of fidelity to this charge that our satisfaction is sweet indeed. It is more than sweet, 'tis proud. Among the many self-evident good effects which such an influence necessarily exerts we may only pause to notice here the higher tone which has been reflected on the medical journals in our own immediate vicinity. The time is but short when the columns of these periodicals were filled with vituperation upon every in- dividual and enterprise which ran counter to interests as petty as selfish. That time, we are happy to be able to say, is now past, and though much credit for this revolution is of course due to those lessons which the constant failure of impotence alone can teach, yet not a little is likewise due to the force of a pure example. It shall be our honest endeavor in the future to present to our readers all that is new, that is useful, that is good in the half a dozen languages from which we can glean our facts. Our exchange list is constantly on the in- crease, correspondingly, our range of Selections. We had hoped before this to be able to present our readers with the ripe fruits of Italy and Spain which we are now prepared to cull, but the papers are not yet at hand. 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Cloth, $5 od; Sheep, $6 oo Medical, Scientific, and other Catalogues sent on application. Any book in the above list sent by mail or express, free of charge, $2 oo Cloth, on receipt of price. 65 West Fourth Street, Cincinnati, Ohio. º * º *- * º YS Carriage Manufacturer, tº Nos. 9 and Il East sixthsº bet. Main & wana, I MAKE NOTHING BUT runsr class work, Of every variety and style, embracing all the improvements in Carriages of any value, many of my own invention and used only by me. My experience in the construction of large Carriages, such as Landaus, Clarences, Landauletts, Broughams, Coupes, Callaches, Coupaletts is unsur- passed. Of - LIGHT FAMILY CARRIAGES Rockaways, Bretts, Victorias, Phaetons, Barouches, Eugenias, Nilssons &c., I make a very ex- tensive variety of light elegant designs of different cost and finish. 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Sixth St., CINCINNATI. ||||||||}|| MM|| ||M|| Fosrº-R's, 167 EAST 34TH-ST., NEW YORK, By Special Appointment Electrical Instrument Makers to the New York State Hospital for Nervous Diseases, MANUFACTURERS OF PORTABLE ELECTRO-MAGNETIC MACHINES, Portable Galwanic Batteries, Continuous Current, Stöhrer's Improved, patented June 1st, 1870, and May 30th, 1871. These Instruments are the most Elegant, Powerful, Effica- * cious, Reliable and Cheapest ever manufactured. Can be instantly set to work or stopped. Will remain in operation for a considerable period without changing the Battery Fluid. Can be carried around Charged and Ready for Use without danger of Spilling the Battery Fluid. - |M|| |||||—|| || ||||||} PERMANIENT BATTERIEs, For Hospitals and General Practitioners, IET IIECTIER, OTDIES. For Eye, Ear, Larynx, Nose, Uterus, Wagina, Bladder, Rec- tum, Feet, Phrenic and Sympathetic Nerves, Eleo- trolysis, Galvano-Caustic, and all Elec- trical Instruments for Medical Use. EXTRA (!TS FRONT THE O PINIONS OF THE MOST JEIH IN ENT IM EM B EIRS OF THIS PROFESS F O N. WM. A. HAMMOND, Prof. of Diseases of the Mind and Nervous System, Bellevue Hospital, says: “Not HING CAN EXCEED THE EFFICIENCY AND CONVENIENCE OF THIS INSTRU- MENT. It possesses the great advantages of supplying both the inducing and induced currents, and enabling the physi- cian to regulate the interruptions, so as to give the shocks very slowly, a matter of great importance in the treatment of Paralytic Disorders.” We are authorized by Prof. Hammond to announce ern- – * * -> phatically that the above extract, and the description of our nº Portable Electro-Magnetic Machines, published in his recent work on Nervous Diseases, has reference only to the im- proved and re-modified Instruments made by our Company. MEREDITH CLYMER, M. 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It gives illustrations and a full description of the Limbs and tells why my attention was called to artificial limbs—my choice in a limb–why I commenced to manufacture them—suggestions to those suf- fering from loss of limbs—is it best to have an artificial limb—why is it that some get artificial limbs and do not wear them—what class of men ought to manufacture ar- tificial limbs—testimonials from the press and from those wearing the limbs—how to order a limb, etc., etc. All communications should be addressed to JAMES A. FOSTER, 911 Chestnut Street, Philadelphia, Pa. No. 60 West Fourth street. Cincinnati, Ohio, or 17.2 Jef. ferson Avenue, Detroit, Mich. SAML. P. THOMAS O R. y DE ALER IN English, French and Scotch GOODs, 34 West Fourth Street, C.A.W.C.A.W.W.? Z"A. Nº. - . Wºº: § * §§ zº &= [… e-w § º:Fº#sº § º º § à £ - ºº: tº 2 º # 2. º º º: º - §§ §ºž ºft % Ée º % & rº º *: tº: ãº.º§ 2- ################ º al sº ## # | ſº # 2 §:# :====> * - º - º/ #=% º # É;# غž" §º2= Fº 2: 3; º º - º Žº --- §§§ 㺠§===#2%%)?ſk= º - - - z * *- - - w The GOOD SAMARITAN HOSPITAL is pleasantly situated on an eminence overlooking the city, at the corner of sixth and Lock streets. It is handsomely furnished throughout, and is provided with all the necessary ap- pointments of a First-class Hospital. Porticoes, with commanding views, surround the whole house, and wide halls and abundant windows secure that full and free ventilation which is so essential to health and comfort. Service is furnished by the SISTERS OF CHARITY, Under the Superintendence of the well-known SISTER ANTHONY, with that care and attention which only they who have sacrificed their lives to such purpose know how to afford. - The regular Medical Attendance of the house is supplied by the Faculty of the Medical College of Ohio, each Professor presiding over his own especial department. Patients may, however, select from the regular profession of the city any physician of their choice. - - The GOOD SAMARITAN HOSPITAL presents oxtra inducements to Invalids throughout the State as a safe and quiet asylum in any case of protracted illness, or in cases, more particularly, requiring Surgical Operation, where some stay is necessary in after treatment. * Rooms vary in price, according to the character of appointments necessary and service required, ranging, in general terms, between $3.00 and $15.00 per week. This includes, of course, the diet list, and every demand of service. tº Address, SISTER ANTHON.Y, Hospital of the Good Samaritan, Corner of Siacth and Lock Sts., Cincinnati. Ohio. ſº - º wº ſº * fººt * - ſº º ſº ºf * : r; . 3. - * * Fº º, # 3 iſ Nºlº c Sº § * . º ÄNº. º ** H ºº: º: i. Fºrm ----------- tº E i. - Tºtº's #. #ji § º *::. b ſ: - |"º . º D i: |ºl | º: ; : 3 #: |ſºlſ.); ºf . illiº- § *I. º: .*H §3. º tº Pº wº º |º; : ºlºfº. : º - ſ § §7: *- tº * - * # alºº & º: [. - * tiº Yºº |T º - #= }}}:2 Fºllº *** * l - - º || "SH!3. - | | * Wºº w º § º º (8. # º * ...Tº D º Sºº º ſ t & * º §: - º G-º-º-º-º- º º - Zº º º ºv | ºffi : *Wyº.º iſ “ U Rººf -- º: º º |ºl. º-e ~ * ~ *-* - #4;… º t ilº ** 5. Stº º & º º liſtſ.< ºff." sº º - º ..-- - ºf . - |Hºlſ - g *. º º- sºil; |Fºº!'" :=º w". M. N.- * * ***-* * il º es- | sº Fºr Sºłº - sº ſº *s-- 7}º rººs E ::...Sºlº ºtºs-rººt tº SººHºº! ==EE §§§liº º tººls: *º- -> º 5- - C޺ -- Esº º º: S º; - º: lºſºlſº *F - - - ºw-ºs- º =::=======E:::::::: Fº- ####### sº: Er. Rºse: E=== CINCINN ATI. —--" IET A C U L T Y . J A M E S G FR A H A M , M. D., D E AN, Professor of the Theory and I?ractice Of Medicine and Clinical IMedicine. 2" ROBERTS BARTHOLOW, M.D., W. W. DAWSON, M.D., Professor of Materia Medica and Therapeutics. Professor of Principles and Practice of Surgery and Clinical Surgery. W. H. GOBRECHT, M.D., Professor of Anatomy. * T. A. REAMY, M.D., P. S. CONNER, M.D., Professor of Surgical Anatomy. JOHN L. CLEVELAND, M.D., JAMES T. WHITTAKER, M.D., Demonstrator of Anatomy. IProfessor of Physiology. SAMUEL NICKLES, M.D., Professor of Physics and Medical Chemistry Professor of Obstetrics and Diseases of Children. CHARLES KEARNS, M.D., Assistant to the Chair of Surgery. W. W. SEELY, MI. D., Professor of L) is eases of the IEye and Hjar, and Secretary of the Faculty ,- T. Louis Brows, M. I.). Prosec tor of Anatomy. E. NoBLE, Janitor, College Building, Sixth St., bet. Vine and Race Electric Chamber Samaritan Hosp. . . . . . . . . . . ... • - • * * 86 Electricity in Labor. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 243 Electricity in Trachoma. . . . . . . . . . . . . . . . . . . . . . . . . . . . 168 Electricity in Tumors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71 Electricity in Vomiting Pregnancy . . . . . . . . . . . . . . . . 60 Electricity Med. and Apparatus. . . . . . . . . 25 Electricity, Prize in . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 Embalming . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 Emperor of Brazil . . . . . . . . . . . . . . . . . . . . . . . . . . . . 188 Encyclopedia Ophthalmology. . . . . . . . . . . . . . . . . . . . . . . . 70 Enuresis, Treatment of . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 168- Epiglottis, Position in Age. . . . . . . . . . . . . . . . . . . . . . . . . 285 Epilepsy, Artificial Induction . . . . . . . . . . . . . . . . . 200 Epilepsy, Management of . . . . . . . . . . . . . . . . . . . . . . . . . 180 Epileptiform Tić . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 253 Ergot in Dysentery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 Ergot in Varices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 180 Ergot in Hemoptysis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 Error of the Empire . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 Eucalyptus in Intermittents . . . . . . . . . . . . . . . . . . . . . . . . 263 Examination Questions . . . . . . • & s = e s s = * * * * * * = . . . 107 Exegetic Document . . . . . . . . . . . . . . . . . . . . . . . . . . . 68s Expectoration in Asthma. . . . . . . . . . . . . . . . . . . . . . . 31 Experiments in Epilepsy . . . . . . . . . . . . . . . . . . . . . . . . . . . . 121 Extra-Uterine Pregnancy . . . . . . . . . . . . . . . 105 Extract of Meat . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 F - Facial Nerve, Spasm of . . . . . . . . . . . . . . . . . . . . . . . . . . 154 False Melanosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 Fecundity of Germs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 Female Students . . . . . .# - - - - - - - - - - - - - - - * * * * * * * * * * * * 307 Female City Physician. . . . . . . . . . . . . . . . . . . . . . . . . . . . 246 First Medical Journal . . . . . . . . . . . . . . . . . . . . . . . . 203 Fish Hook in Oesophagus. . . . . . . . . . . . . . . . . . . . . . . . 309 Fisk’s Brain, Weight of . . . . . . . . . . . . . . . . . . . . . . . . 48 Fissure of Lids. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . _T Fistula for Cystitis . . . . . . . . . . . . . . . . . . . . . 40–84–250 Fistula in Ano. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .218 Foetation Extra-Uterine . . . . . . . 19 Foster, Dr. H. C., Death of . . . . . . . . . . . . . . . . . . . . . 150 French Patriotism . . . . . . . . . . . . . . . . . . . . . . . . . . . 179 G Gastric Juice in Cancer, etc . . . . . . . . . . . . . . . . . . . . . . . 62 Generous Testatrice . . . . . 141 Generation Artificial. . . . . . . . . . . . . . . . . . . . . . . . . 261 German Professors' Salary . . . . . . . . . . . . . . . . . . . . . . . . . 203 German Provisions for Science . . . . . . . . . . . . . . . . . 79 German Therapy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 275 Germs, Healthy Blood. . . . . . . . . . . . . . . . . . . . . . . 147 Goitre, Iodine Injections in . . . . . . . . . . . . . . . . . . . . . . . . . 241 Gomorrhea, Water Treatment. . . . . . . . . . . . 34 Good Samaritan Hospital. . . . . . . . . . . . . . . . . . . . . . . . 36 Graduates of 1872. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 179-119 Greene, Prof. W. G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 307 Guarana in Sick Headache . . . . . . . . . . . . . . . . . . . . . . 220 Gun Shot Wounds, Pathology. . . . . . . . . . . . . . . . . . . . . . 244 H Płair Changes . . . . . . . . . . . . . . . . . . . . * * * * * * * * * * * * * * 148 Hair Pin in Bladder. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3.11 Harley's Urine and Derangements . . . . . . . . . . . . . . . . . 308 Heavily Backed Journal . . . . . . . . . . . . . . . . . . . . . . . . . . 179 Heels vs. Brains. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67 Hemorrhoids . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 217 Henry’s Venereal Dis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 260 Hernia Cerebri . . . . . . . . . . . . . . . . . . . . . . . . . . 301 Hernia, Digital Dilatation. . . . . . 168 Hernia, Irreducible . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Hernia, Puncture of... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 Hero Hunting . . . . . . . . . . . . . . . . . . . . . . . . . . . . • * * * * * * * 2 Home News . . . . . . 35–72—84–96–108-119–132–144–180–204–228 Homoeopathic Surgery. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250 Honors Declined. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90 Honors Reciprocated . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 Honors to Dr. Gill. . . . . . . . . . . . . . . . . . . . . . . . . . . * * * m = 2 * 130 Honors to Physicians, Prince. . . . . . . . . . . . . . . . . . . . . . . 59 Hop Pillow. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67 Hoppe Seyler . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80 Hospital Capacity, Vienna . . . . . . . . . . . . . . . . . . . . . . . . . . 54 #º Beni... d Strapping . . . . . . . . . . . . . . . . . . ; rocele, Tapping and Strapping . . . . . . . . . . . . . . . . . . . 3 #. Treatment of. . . . . . . . . . . . . . . . . . . . . . . . . . . 33 Hydrophobia, Pathology of . . . . . . . . . . . . . . . . . . . . . . . . . 29 Hydrophobia, Spontaneous . . . . . . . . . . . . . . . . . . . . . . . . . 127 Bydrothorax, Thoracentesis . . . . . . . . . . . . . . . . . . . . . . . . . 254 Hyperperexia, Cold in . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 191 Hysteria, Diagnosis of... . . . . . . . . . . . . . . . . . . . . . . . . . . . 218 Ice in Intestinl. Obstruct. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 Icterus Epidemic, Paris . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141 Impetigo Rodens, etc. . . . . . . . . . . . . . . . . . . . . . . . . 74–90–126 Impotency . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 227 Ind. State Med. Soc . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 273 Infection, Cause of . . . . . . . . . . . . . . . . . . . . . . . . . . 35 Inoculat. Small Pox by Skin Grafts . . . . . . . . . . . . . . . . 309 Intellect Developed by Electricity. . . . . . . . . . . . . . . . . . . 261 Intermittent Blepharospasm. . . . . . . . . . . . . . . . . . . . 153 Intermittent Fever, Eucalyptus in . 263 Intestinal Invagination . . . . . . . . . . . . . . . . . . . . . . . 37–252 Intra-Urine Intermit. Polyp . . . . . . . . . . . . 191 lntussusception, Novel Treatment . . . . . . . . . . . . . . . . . . . . 251 Insanity, Law and Med. Relat . . . . . . . . . . . . . . . . . . . . . 139 Iodine in Goitre . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 241 Iodine in Vomiting. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 286 Ipecac Enema in Dysentery. . . . . . . . . . . . . . . . . . . . . . . . . . 74 Iron, Coloring Matter Nature . . . . . . . . . . . . . . . . . . . . . . . . 19 J Jackson, Dr., Death of . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 203 Jackson's Cough Syrup . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190 Jager, Death of . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80 Japan Med. School . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 286 Jewish Medicine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 Journal Changes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118 Jugulated Med. Colleges . . . . . . . . . . . . . . . . . . . . . . . . . . 226 P& Kentucky Med. Society . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 178 Kidney, Removal of . . . . . . . . . . . . . . . . . . . . . . . . . . tº 287 Knighthood for Cormack . . . . . . . . . . . . . . . . . . . . . . 167 L Lacto-Phosphate Lime in Fevers . . . . . . . . . . . . . . . . . . . 128 Ladies, New Profession for . . . . . . . . . . . . . . . . . . . . . . . . . . 275 Lamp Bracket, Anderson. . . . . . . . . . . . . . . . . . . . . . . . . . . 13 Largest Practice in the World. . . . . . . . . . . . . . . . . . . . . . 141 Larynx, Section Cartilages . . . . . . . . . . . . . . . . . . . . . . . . . . 46 Laughing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 117 Laycock on Ears . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176 Lessons from Sandringham . . . . . . . . . . . . . . . . . . . . . 129 Liberal Party in Prussia. . . . . . . . . . . . . . . . . . . * * * * * * * * * * 166 Life Insurance Fees . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225 Life, Painless Destruction of. . . . . . . . . . . . . . . . . . . . 104 Liquefaction of Corpses . . . . . . . . . . . . . . . . . . . . . . . . . . 26 | Lithotomy and Lithotrity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 251 Liver, Cirrhosis of. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 Logan's Consumption . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70 Lostorfer's Corpuscles. . . . . . . . . . . . . . . . . . . . . . 189–248–260 Loyalty to Science . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104 Lyell’s Displacement Radius. . . . . . . . . . . . . . . . . 183 M Marriage and Crime. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130 Medical College of Ohio. . . . . . . . . . . . . . . . . . . . . . . . . . . 172 Medical Councillors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 Medical Electricity and Apparat. . . . . . . . . . . . . . . . . . . . . 25–86 Medical Fees in Italy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 Medical Jurisprudence . . . . . . . . . . . . . . . . . . . . . . . . . . 142 Medical International Congress . . . . . . . . . . . . . . . . . . . 148 Medical Science in Quito. . . . . . . . . . . . . . . . . . . . . . . . 179 Medical Senators . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 226 Medical Soc. State Committees . . . . . . . . . . . . . . . . . . . . . . 12 Medical Students at Vienna . . . . . . . . . . . . . . . . . . . . . . . . . 244 Medicine, Preventive . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250 Medlicott Case . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189 Membrana Tympani Movements. . . . . . . . . . . . . . . . . . . . . . 241 Menstruation, Mammary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190 Menstruation, Opportunity of . . . . . . . . . . . . . . . . . . . . . . . . 249 Milah and Mohel . . . . . . . . . . . . . . . . . . . 165 Millenial Celebration. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 307 Mind Infl. on Body . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169–282 Minutes Amer. Med. Assoc. . . . . . . . . . . . . . . . . . . . . . . . . . . 309 Morphia and Chloroform . . . . . . . . . . . . . . . . . . . . . . . . . . . 192 Morphia Hypodermically . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 Munich Jubilee. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 307 Munificent Donation . . . . . . * * * * * * * * * * * * * * * * * * * * * * * * * * * 179 Muscular Contraction, Pressure . . . . . . . . . . . . . . . . . . . . . 264 Narceine Hypodermically . . . . . . . . . . . . . . . . . . . . . . . . . 168 Navy, Med. Service in the . . . . . . . . . . . . . . . . . . . . . . . . 44 Nerves, Stretching of . . . . . . . . . . . . . . . . . . . . . . . . . . 2S1 Nervous Diseases, Origin and Treatment. . . . . . . . . . . . . . 157 Neuralgia, Facial Convulsive . . . . . . . . . . . . . . . . . . . 138 Night Watches of Berlin . . . . . . . . . . . . . . . . . . . . 307 Noli Me Tangere . . . . . . . . . . . . . . . . . . . . . . . . 74–90–126–136 - s : . . . ~~ - - . . . . .” ... " -- ºr 4 - - , , , - - * - * , - • , . F - ... •. ! * • * , - - . ...; * { . . . - s= y- - * - -*. *. - • { - - " - - r = * 3. - ń. ; * ... * * - - - - - - - , X- - Ö . Spleen; Tumors of . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 . . . •. : & * ~ - , ** *~. > *. r * ©esophagoscope. ... : . . . . . . . . . . . . . . . . . . . . . . . . . . . -- - - - 31 Qhio State Med. Society. , ..., Qldest Medical College in the Oldest Medical Work... . . . . . * Old Times . . . . ‘.….. . . . . . . . . . . . . . ... tº . - ... . . . . Opacities Tattooed. . . . .‘. . . . . . . . . . . . . Qpthalmia Neonatorum . . . . . . . . . . . . . . . . . . . . . . . Opthalmia Sympathetic. . . . . . . . . . . . . . . . . . . . Opthalmology in Art. . . . . . . . .....: Opium, Import. of . . . . . . Opium, Principles of... 3-, cº-ºe.'. * * *. Qppolzer's Successor. . . . . . . . . . . . . . . . . . . . . . . . .. . . . . .21 w is 4 & 5 tº º a West . . . . . * . . . . . . . .227 • * * * * * * * * * * * * * Opportunity, an: . . . . . . . . . . . . . . . . . . . . . . . . . . . . ... ... 226. • * Y= - - - , , , , , a • * * * * Otólogy, Report on...….... . . . P Palm to the True Victors...' . • * * * * * * * * * * * * * * * * * * * * Paris Faculty. . . . . . . . . . . . . . . . . . . . . . . Paronychia, tr. of. . . . . . . . . . . . * . . . . . ". . . . . . . . . . . . . . . . . . . Pathology and Therapy of Still-birth. . . . . . . . . . . . . .” Patriotic . . . . . . . . . . . . . . . . . . . . - - Paying a Fine . . . . . . . . Penis, Amputat, of . . . . . . . . . . . . . . . ." - Penis, Constriction of... . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167 Persia, the Pest in . - Phag. Penis, Opium in... . . . . . . . . . . Phil. Hospital, lockley. . . . . . . . . . . Phrenic Neuralgia. . . . . . . . . . . . . . . . Physiology of Virus and Infect. Dis. . . . . . . . Plague in Bombay. . . . . . . . . . . . . . . . . . . . . . . . . . ‘. . . . Pleuritis, Treatment of.... . . . . . . . . . . . . . . . . . Poisoning by Atropia. . . . . . . . . . . . . . . . . . . Polyp. of the Uterus, Fibrous: . . . . . Polypus. Uterine Intermittent Polyp Uterine, Removal of . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 Pregnancy, Extra Uterine Preputial Calculi . . . . . . . Prince, Cure of Professional Prerequisites Professions, the Liberal . . . . . . . . . Professors in Germany Promotion of Mediocrity . . . . . . . . . . . . . . . . . . . . . . Paralysis Traumatic. º.º. . . . . . . . . . . . . . . . . . . . . . . . . ... 203. * * * * * * * * * * * * * * * * s & e º f * * * * * * * * * * * * * * * * * * * * * & s & a s e s s - s s ºr e º s = * * * * s = < * * * * * • * * * * * * * * * * * * * * * * * • * * * * * * * * * * * * * * * * * * * * * * * * a 9 s m º e < * = < * * * * * * * * * * * * * * * * * * * * * * = < * * * * * * * * * & e º nº e º º sº a # * * * g º a • * * * * * * * a 3 s a a e < * * * * * s & s = < * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * • . * * * * * * * * * * * * * * * * * * * * * * * . . . , s a s = < * * * * * * * * * * * * * * * * * * * * * * * * * * * * • * * * * * * * * * * * * * * * * * * * * * * • * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * s & s 4 e s s a 4 & a s = * * * * * * Pruritus Vulvae, Treatment of..... . . . . . . . . . . . . . . . . . . 83 Puncture for Abdominal Tympanites. . . . . . . . . . . . . . . 5 Puncture of Hernia. . . . . . . Quacks and Penn. Hosp. . . . . . . . . . . . . Questions Examinat. . . . . ~Quinine Collyrium . Quinine, Effects on Quinine in Trachoma Quinine Salts, Relat. Quito, Med. Science in * * * * * * * * * * * * * * * * * • e º a s º ºs e º e º sº a w = * * * * * * * * * * * * • * * * * * * * * * * * s s * * * * c e s ſº e s = e s a r * * * * * * * * * * * * * * * * * * * * * Radius, Lyell’s Displace’t. . . . . . . . . . . . . . . . . . . Reimplantation Teeth ... . . . . . . . . . Report C. m. Pensions Review Brown Sequard . . . . Rheumatism, Acid Treat & a tº Rheumatism Infl. on Character. . . . . . . . . . . . . . . . . . . Rites Foundation Sacrifice * * * * * * * * * * * * * * * * * * * * * * * • 2 g º a s a s a e s tº s = * * * * * * * * a. * * * * * * * * * * * * * * * * * * * * * * * & 8 & 9 & 3 m ^ 4 tº º ºr 26() 94 A a 4 tº s & # * * * * * * * * * 30'ſ 174 261 Salisbury vs. Lostorfer Sarcina in Blood . . . . . Sayre, Dr. Decorated Science of Man . . . . . . . . . . . . . . . . . . . . . . . . . . . . Science, High - - - - Soury Epidemic . . . . . . . . . . . . . . . . . . . . . . . . . . . 70-91–196 Sea Sickness . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 163–175-312 Senses. Fallacies of . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Sick Headache Sick Headache, Treatment of. . . . . . . . . . . Signs of Death . . . . . . . . * * * * * * is is ~ * Signs of the Times. . . . . . Skin (}rafts * * * Skin Human, Binding. . . . . . . . . . . . . . ‘. . . . . . . . . . . . . . Skin Puncture in Anasarca * - Skoda Slee §. Pox in Berlin Small Pox in Germany . . . . Sinall Pox, New Remedy for . . . . . . . . . . . . . . . . . . Smith's Dis. Children Solid Food in Typhoid Fever Spasm of Levator Anu. . . . . . . . * * * * * * * * * * * * * * * * * * * * * * * * * * * * s s a s , , , s = * * * * * * * * * * * * * • * * * * * * * * * * * * * * ºr e º a s. s • * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * s s = < * * * * * * * * * * * tº e < * * * * * * * * s s = e s a s = * * * * * * * * * * * * * * * * * * * * * * * g e º * * * * * * * * * g a g º si º e º e < * * * * * * * * * * * * * . . . . . . , s , , , , , , , s e < * * * * * * * * * * * * * * * * * * * * * * • * * * * * * * * * * * * * * & s , is a s & © 2 & 6 s is a s a sº e º a s g º º s º * . . . . . * * * * * * * * * ... . s = a + r * * * * * * * * * * * * * & º f * * * * , , ; a s a s a s , a g º is a s ºr a s a e º e = * * * * * * º, º a g º is s tº e º sº & & # e º e º sº tº & F * * * * * * * * * * > . . * * * * * * * * * * 203–224–288-289–300 - . . . . 179 - * ^- • ** ** . . • . . . . ----- ". . . . . . . . * * *, 6'ſ ...i - • ** { -: ‘. . . . . 363 * 52. º ... 165 |* Stricture, Prostatic . . . . . . . . . . . . . . . . . . . . . . . . S, - - º: Çord, Ghāfigésºfº. 3:. . . . . . . . . . . . . . . . 225 $germatorrhea, tr. di . . . . . . . . . . . . . . . . . . . . . . . 28: - . Spring Course . . . . . . . . . * . * ~ * & t. Stantön, Wra. Letter. . . . º Abscess of . . . . . . . . . ... . . . . . . . . . . . . . . 156*. H. Şăinal Cord. Disease of... . . . . . . . . . . . . * * * * * * * * * * . * * * * * * * * * Statistics of the Race . . . . . . . . . Štěřility, tr. of - Still-births . . . . . . ....... . . . . . . . . St. P Sul and St. Luke . . . . . . . . . Stomach, Rapture and Wounds of . Strasbourg . . . . . . . . . .... ". . . . . . . . . Strasbourg School. . . . . . . . . . . . . . . . • * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * - a . . . . . . . . . ... 143 - Strasbourg Festivities . . . 275 Stricture; "Urethra . . . . . . 2. Study of Science. … . . . . . . . . . . . . . . . . . . . . .7 Subcutaneous Aspiration . . . . . . . . . . . . . . . . . . . . . . . 15 Šubjects, Preservation of . . . . . . . . . . . . . . . . . . . . . . . . . . 28 ºf $uccessor to Zouave. . . . . . . . . . . . . . . . . . . . . . . , . . . 130 Suicide by Morphia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 Sugar, Infl. of fººt * * * * * . . . . . . . . . , * * * * * * * . . . . . . . . . 44 Suit for Forgery. . . . . . ‘. . . . . . . . . . . . . . . º. . . . . . . f6() Sulph, Acid in Contusions . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 Surgery of War . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . .54 Syphilis Cummittee . "… . . . . . . . . . . . 150 Syphilis Corpuscles 4 º' Syphilis, Microscope in . . . . . . . . . Teaching and Practising..... . . . . . . . . . . . . . . Teeth, Reimplantation of... . . . . . . . . . . . . . . . . . . . ; Teratological. . . . . . . . . . . . . . . ... - Testicles Undescended. . . . . . . . . . . . . . . . . . Testimony to Italian, Physician. . . . . . . . . . . . Tetanus, Arsen. Quinia in . . . . . . . . . . . . . Tetanus Treatment by Chinese . . . . . . . . . . . . . . . Tobacco Smoke, Action of . . . . . . . . • *. Tobacco, Tolerance of . . . . . . Tonsils, Excision of 'Torticollis. . . . # = s. * * * * Tracheotomy-Galvano-Caustic . . . . . . . . . . . . . . . . . . . . 268 Trachoma, Electricity in Transfusion of Blood . . . . Tremor of Hand Trepanning the Sternum . . . . . . . . . . . . . . . . . . . . . . . . . . Trophic Neuroses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . '76 Tumor, Electric Treatment . . . . . . . . . . . . . . . . . . . Tumor, Injections into . . . . . * * * Turkish Med. Journal . . . Turpentine in Ear Disease. . . . . . . . . Tympanites, Puncture in . . . . . . . . . • * * * s • • * * * * : * * * , , , - - , , , º, . . . * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * > . . . . • * * * * * * * * * * - - - - - - - - , , . . . . . . . . * * * * * * * * s = e º a s s s is a • , s , s , s , e. * * * * * * * * * * * * * * * * * * * * * * * * * * s 5 & 8 º' & * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * e s 3 & E ºr * * * * * * * * * r s s a e = * * * * * * * * * * * * * * * * * * * * * * * * * * * * * s e s = < s # 8 & = s : * * * * * * * • * * * * * * * * * * * * . Urea formed in Liver . . . . . . . . . . . . . . . Uterus, Carcinoma . . . . . . . . . . . . . . . . . . . . . . Uterus Contraction Force Uterus Double * * * Uterus, Fibrous Polypus of. . . . . . . . Uterus, Fibrous Tumor of - * Uterus Polypus, Point in Diagnosis . . Uterus Subinvolution . . . . . .”. Uterus Versions and Flexions . . . * * * * * * * , , v 4 tº s s a º y a s e tº e º s * * * * * * * * * * * * * * * * g . g º 'º w w tº e º s * * * 4 * r * * * * * * * * * - - - - - - - - - - - - - - * * * * * * * * * * * * * * * * * * * • * * * * * * * * * * * * * * * * * * * * * * * Vaccination Papers . . . . . . . . . . . . . . . . Vaccination Cheaper-than Shaving . . . . . . Vaccination Martyr. … . . . . . . . . . . . . Waledictory Address'. . . . ." Varices treated by Ergot - Venerable-Surgeons.” . . . . . . . . . . . . . . . . . . . Ventral Body Heat. . . . . . . . . . . . . . . . . Vesicants in Ear. Disease... Wirehow Peripatetic. . . . . . . . . . . ' Wivisections - 't Vomiting in Hernia. . . . . . . . . . Womiting, Iodine in . . . . * * * * * * * * * * * is tº * * s • * * * * * * * * * * * * * * * * * * * * * * * * * * * • * > . * * • * * * * * : * * * * * * * * * * * * * . . . ; * * * • * * * * * * * * * * * * * * * : * * * * * B is s ºf s. * * * * * * * * * * * * * * * * * * * • * * * * * * * * * * * * * * * * * * * * * * * * * * s = Watson Shryock, West Virginia State Medical Society Whisky, Formula for . . . . . . * * * * * * '... : : . . Whiting, L. M., M. D., Note from . . . . Wrist, Backward Dislocation. . . . . t Wurzburg Clinic. . . . . . . . . t Xylol in Small Pox . . . . . . . . . . º 80 . . . . . . . . . . . 168–276 • * * * * * * * * * * * * * * * * * * * * * * * er ; : : - & # * * * * * . . . . . . . . . . . . . . . . . . . . . 128. ... 184 ſv-3 ¿、