*/2 5. 4 :- *...*.*.*.* à. lºvoz, 1. JULY, 1877. NO. I. | # |. g t K THE LINTON DISTRICT MEDICAI. Journal. AºS. •. A SEMI-ANNUAf, JOURNAL, 2- Under the control of the Linton District Medical Society of Missouri. { Å, * EDITORS : ſ S. N. RUSSELL, M. D., Mexico, Mo. J. H. DUNCAN, M. D., CoLUMBIA, Mo. Terms, $2.00 Per Year, in Advance, COLUMBIA : STATESMAN Boº, #sº Job PRINT. * y t ‘. & cºs\CONTENTS, ſº PART I. ORIGINAL COMMUNICATIONS. PAGE. Article 1. Hysteria--W. W. Macfarlane, M. D. . . . . . . . . . . . . : . . . . . . . . . . . . . . . . . . 1 Article 2. Ptosis Mydriasis Strabismus--W. Dickinson, M. D. . . . . . . . . . . . . . . . 5" Article 3, Expulsion of a Toad from the Alimentary Canal—John Bryant, | Jr. M. D . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * * * * * * * * * * * ... ... 10 Article 4. Therapeutic Properties of Ammonium Carbonate—-W. A. Jack- man, M. D . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 Article 5. A case of Malformation--W. F. Humphreys, M. D. . . . . . . . . . . . . . . . 18 Article 6. As Others See US—G. W. Broome, M. D. . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 PART II. SELECTED. *- Malaria--C P. Russel, M. D. . . . . . . . ............................... ......... 22 Summer Complaints of Children.--J. M. Allen, M. D. . . . . . . . . . . . . . . . . .... . . . . . . . 37 Salicine in the Treatment of Rheumatism--A. D. L. Napier, M. D. . . . . . . . . . . . 46 PART III. Records of the Linton District Medical Society....... . . . . . . . . . . . . . . 48 Annual Address of the Retiring President, Dr. W. T. Lenoir, Columbia, Mo. 59 Introduction... . . . . . . . . . . . . . . . . • * * * * * * * * * * * * * * * * * * * * * * * * * g e º e e s m e º a • * * * * * * * * 64 PART IV. Editorial Abstracts and Selections ....................... . . . . . * - - - - - 68 T H E I.INTON DISTRICT MEDICAL JOURNAL. JULY, 4877. ORIGINAL COMMUNICATIONS. ARTCLE I. IIYSTERIA.—BY W. W. MACFARLANE, M. D., MEXICO, Mo. The names applied to diseases by the ancients were fre- quently unfortunate, having a tendency to mislead the physician—as examples we may mention Typhus Fever, Tic Douloureux, Rheumatism, Hysteria, &c., &c. Many names have been changed, the modern names indicating the nature of the disease, to some extent at least. Hysteria still retains its heathen name indicating its heathen pathology. The name, from Šaréga, the womb, would lead one to believe that the disease was purely uterine, which is not true. Also that only females are subject to this disease, which is not true. Hysteria is not more remarkable for its frequency than for the numerous forms under which it may appear; re- sembling most of the diseases which afflict mankind, as- suming many different forms, and, like the Grecian deity Proteus, possessing the power of changing itself into many and opposite appearances. Hysteria is really an abnormal condition of the nervous system, and is a disease and not purely imaginary. There is generally an entire absence of anatomical lesions but sometimes the disease is secondary to or a symptom or a 2 ORIGINAL C ) MMUN l CATIONS. -** *-*. result of uterine disease. An unusually excitable nervous system predisposes to hysteria and this predisposition may be created. When this predisposition exists many causes are suffi- cient to excite the manifestations of the disease—viz: Vicious practices, imaginative fiction, shocks to the nerv- ous system, etc. The symptoms are various; among the most prominent may be mentioned, a disturbance of the special senses, all of which may be so disturbed at the time of attack as to produce temporary illusions of sight, hearing and smell. The voluntary motives may be pervcrted, resulting in con- vulsions, catalepsy, coma and paralysis. These are also temporary but liable to recur at any subsequent attack. There is generally more or less insomnia, impaired appe- tite, cool skin and constipation. The paroxysms may come on suddenly, without any premonitory symptoms, continue for an indefinite time, and the recovery may be as sudden and unexpected as the attack. (I wish it understood that I mean that this recovery is only apparent, and only a cessation of the most prominent symptoms of the disease.) Possibly other symptoms less frequent might be men- tioned--viz: Indigestion, obstinate constipation, hardness and enlargement of the breast, unreasonable laughter, floods of tears, pains in different parts of the body, dysu- ria colic or something resembling colic, hiccough, con- stant cough, deafness, blindness, &c., &c. CASE.-Miss K. Age I 5; student; very intellectual ; well advanced in her studies; had been unwell for some months; frequently had fainting spells in the school room; became worse and stopped school, but had not improved in her general health; had menstruated scantily; poor appetite; slept badly; complained of a constant pain in the back. Some four months or more after stopping School, while under some nervous excitement, she fell HYSTERIA. 3 down in a fit. For a week or more she was insane, then improved slowly for a time, but the convulsions recurring | she became very insane. Had to be fed, urinated in bed unconsciously, had the hysterical cough and hiccough, frequent convulsions, sometimes slight but occasionally severe; finally, deafness and blindness. She became ema- ciated; had all kinds of delusions. After being in this condition for months, being even at death's door for months, she recovered, and is now in excellent health, bodily and mentally. The young lady has a great uncle who was insane. Her grandfather was slightly insane for a short time. An uncle died in an asylum. An aunt committed suicide. This young lady had convulsions simulating epilepsy. She was evidently insane for some time. She had the peculiar excitable nervous system with the hereditary taint. She had hysterical insanity. Dr. Aitken thus de- fines Hysteria: “Hysteria is a chronic morbid condition of the brain and nervous system and the phenomena may simulate the phenomena of almost any other disease, and these phenomena are usually of short duration and parox- ysmal occurrence.” In consideration of the symptoms presented in this case (which is a typical one) are we not warranted in regarding Hysteria as a form of insanity ? Indeed, I believe that Hysteria is insanity. “The deep shades of Hysteria border upon and even enter the con- fines of insanity.”—Cowly. A celebrated French physician, Dr. Boismont, says, “when moral disorders are excited by nervous affections, that is to say by Hysterical affections, they are accompa- nied by extraordinary phenomena, hallucinations illusions, delusions and such like.” And again he says hallucina- tions themselves are insane. In all works on insanity, Hysteria is always one of the classificati ons. But enough for the present on this part of the subject, and a few words on the treatment; remembering that Hysteria does occur 4 ORIGINAL COMMUNICATIONS. in male subjects and among children both male and ical. female. The treatment of Hysteria is moral, hygienic and med- If the disease is the result of physical disorders, these must be treated on general principles, and in Hysteria, as in insanity, when the cause is removed the Hysteria is cured. * -- The moral treatment is much the same in this disease as in insanity. First gain the confidence of your patient. Listen patiently to her or his complaints, satisfy her that you thoroughly understand her case and can benefit if not cure her, and your work is half done. Tonics and seda- tives are the most effective—iron, pyro phos. iron, the bit- ter tonics, with the bromides and valerian in some form I have found best. Especially is a tonic course indicated if the subject is emaciated. If the subject is in robust bodily health, as is frequently the case, the treatment must be chiefly moral and sedative. In a word, the hysterical pa- tient must be treated as an insane patient, varying of course according to the case of each individual. The consequences of hysteria are much less serious as far as the life of the patient is concerned, than the vio- lence of the symptoms would lead us to fear. It is hard ly ever fatal in itself, but the secondary effects may and undoubtedly sometimes do prove fatal. - It was stated in the beginning of this article that the predisposition to Hysteria may be created. The want of exercise in the open air and sunshine is a prolific source of Hysteria. Boarding schools, conducted as they gener- ally are, are almost or quite a curse to our country. Young girls, just budding into womanhood, at the very time of life when they most need active exercise and sun- shine to develop them into beings fit to fulfill the duties of life, are converted into mere hot-house plants. The brain is over-worked, the body not worked at all—the conse- quence a shattered nervous system, Hysteria. ARTICLE II. PTosis-MYDRIASIS-STRABISMUs.—BY WILLIAM DICKINSON, M. D., St. Louis, Mo. John White, 28 years of age, of spare figure and low stature, a book-keeper, first presented himself to me in April, 1876. His parents never suffered from cerebral affections, but died of some form of fever. A brother several years his senior, however, died of apoplexy at about the age of 50 years. He himself has never suffered from any form of brain disease, nor from falls or blows upon the head; but has uniformly enjoyed good health, and is a man of tem- perate habits. About ten years since he contracted syph- ilis; all evidences of which, after treatment continued during four weeks, apparently disappeared and have never in any degree since returned. In the spring of 1875 a friend observed and called his attention to the condition of the pupil of the left eye, it being much larger than that of the other, though he him- self had not noticed this peculiarity, nor any other affec- tion of the eye. About ten days before his first visit, hav- ing one night retired as usual in the perfect exercise of all his faculties, he discovered on the following morning that he had contracted a severe cold and that he could not completely raise the left eye-lid; indeed it drooped so low as to interfere with vision. A day or two later, his appre- hensions being aroused he tested his vision and then for the first time appreciated the fact, (probably present for a year) that he could not with the left eye clearly discern small objects, and with it could only read large print; but objects at a distance were perceived with nearly the same distinctness as with the other. w When first seen by me the most manifest symptoms were Ptosis—the lids of the left eye being nearly in appo- sition,-and Mydriasis—the diameter of the pupil being three or four times that of the right; (the latter, however, 6 ORIGINAL COMMUNICATIONS. was abnormally small,) the pupil was also very sluggish responding but little to the access or the absence of strong light—the same was true of the right——but both readily affected by the instillation of atropia. In the af- fected eye, the power of accommodation was almost en- tirely wanting, he being scarcely able with it to discern No. 8 of Snellen. The function of the second (optic) nerve had escaped complication. During the two days | succeeding, Strabismus divergens supervened together with inability to freely turn the globe upward or down- ward; but by conscious effort of the associated muscles the globe could be restored to the median position, In consequence of this strabismus, diplopia (double vision) was presentedto a degree which seriously interfered with his business. His sense of hearing was also greatly impaired, the hearing distance of the right ear being only four and and that of the left three inches. The functions of the other cranial nerves were retained in their normal exercise. The physiognomy of the affection being so well defined the diagnosis was not difficult; lesion of the third cranial nerve was the occasion of the symptoms present. The ptosis and imperfect excursion of the globe upward were due to paresis of the divisions of the superior branch inner- vating the levator palpebrae and the Superior rectus, respect- ively—the divergent strabismus, the imperfect excursion of the globe downward and its rotation upon its antero- posterior axis were the result of paresis of the several di- visions of the inferior branch of the same nerve; and since the ophthalmic ganglion derives its motor-endow- ments immediately from this nerve, the mydriasis and im- perfect power of accommodation must be referred to the common paresis of all the branches indicated. The nerve under consideration is more liable to paresis and paralysis than any other, and is generally the result of pressure. If we locate the cause in the orbit we must assume a com- mon cause acting upon all the branches of the third nerve, sparing the fourth and sixth which innervate the superior • * * * *** ** - - *** - - - - t PTOSIS-MYD RIASIS-STR. A. IBISM U.S. 7 * = hºmºe oblique and the abducens muscles respectively. Though such anomalous partiality might be possible, in this case it is scarcely probable. We must therefore seek for the seat of the lesion within the cranium and most probably at the base of the brain. It may be the result of a sero- albuminous exudation or of hemorrhagic extravasation ; but with greater probability I attribute the symptoms to the development of a gummy tumor or of a syph- ilitic node in this region at some point between the origin of the nerve and its entrance into the orbit, by which, through mechanical pressure or by inducing nutri- tional changes in the nerve itself, the normal performance of its function is interfered with. The effects of lesions of the third nerve which are of intra-cranial origin may be sudden or slow in their appearance. The first may partake of an apoplectic character or may arise from violent exer- tion, mental emotion, excessive mental application, sun- stroke, injuries to the head, &c. The second advances with the progress of the cerebral disease; among the causes may be enumerated basilar meningitis, aneurism, exostosis, tubercular or other deposits, and cysts at the base of the brain. In the early stages of either of these forms the symptoms may remit and afterward recur. In the first class of cases there may be a perfect recovery; in the second, those of slow development, there is little expectation of recovery or of permanent amelioration by treatment. Lesion of the nucleus of this nerve at its origin would induce the symptoms given, but peripheral disease is by far the most frequent, and of all causes syphilis is the most common. Von Grafe thinks that about one-third of the cases of paralysis of the motor-oculi, are due to this cause. In many cases it is quite impossible to ascertain with any degree of accuracy at what precise point the lesion is situated ; nor is it important ; one may be con- tent with the knowledge that the patient has suffered from venereal disease, and with this fact persistently kept in view 8 origiNAL CoMMUNICATIONs. we frequently find under appropriate treatment a very rapid recovery ensuing. * , In all cases of paresis or paralysis of the oculo-moto- rius, our prognosis must of course depend upon the con- ceived cause or causes. If these can be removed or re- leived, a favorable prognosis can be given. If the cause is situated within the orbit, (e-g) a tumor not malignant, or an abscess, or if functional and the resultant of a reflex action, the prognosis is favorable. Those causes, in fine, that are of peripheral origin and especially those depend- ant upon rheumatic affections, furnish us with the most favorable prognosis, especially if the patient applies soon after the invasion of the disease. If on the other hand, the affection is due to some grave cerebral lesion accom- panied by manifest symptoms of nerve degeneration or softening and if it has existed for a long period the prog- nosis must be unfavorable. ..y Treatment.—-Since ptosis was the chief symptom ob- served and that for which I was primarily consulted, my treatment was predicated upon the diagnosis that the paral- ysis of the levator palpebrae was of rheumatic origin, su- pervening upon the existence of the gummy tumor desig- nated above and this was made chiefly on account of its sudden invasion; the patient had been exposed to currents of air; he had taken cold, and ptosis was present. We are frank, however, to confess that the pathological changes which occur in these rheumatic paralyses have not re- ceived a satisfactory explanation, and we do not know ex- actly whether deposits or other changes take place in the substance of the muscles distributed to the affected part, or whether the fibrous tissues which invest the nervous trunks are the seat of the rheumatic inflammations. Hav- ing formed my diagnosis, I administered a brisk cathartic and applied to the eye a solution of calabar bean, with the view of securing contraction of the pupil, the dilata- tion of which had for months existed. This was followed by Pot. Iod. and Brom. alone and in combination, and PTOSIS-MY DRIASIS-STRA EISM U.S. 9 * * later by Hyd. Prot, Iod., and Bi-Chlor., and subsequently by the regular and persistent use of galvanism. Obvious amelioration of the symptoms speedily followed, the pa- tient recovered to a good degree the normal use of the levator palpebrae muscle, and progressively the power of accommodation, he being able to read much smaller print than at first. He also regained ultimately almost perfect exercise of the internal rectus muscle, thus annihilating the strabismus, and also the complete use of the other ocular muscles involved. During the treatment partial relapses occurred on several occasions, from which he soon recovered, and he is now able to discern with the affected eye much of No. 1 Snellen, the smallest print in common use. ...” A cure seems to have been achieved; but none can promise exemption from liability to a return of the same affections or to the Supervention of a more grave cerebral disease. A brother died suddenly of “apoplexy;” here is manifested a family proclivity to complicate or aggra- vate any existing conditions that his own habits may have induced. He confesses that he has experienced the con- sequences of vicious indulgences, and though he has en- joyed an immunity from the effects of syphilis for a dec- ade of years, who shall declare that his escape from its tenacious and venomous folds is even now wholly secured? The coral insect in the fulfillment of his mission, building unseen, diligently constructs his tiny shell, his home, his | fortress and his tomb; till in process of time the marine mountain reef defies the storm and wrecks both noble ship and her crew in the unequal encounter. Who then shall assert that the present aggregation of symptoms presented in this case is not the legitimate product of the infection in earlier years received, which, clandestinely existing dur- ing the subsequent years, has insidiously and unsuspect- ingly elaborated those vital elements, that, resisting the best appliances of our art, shall know no limit or cessa- 10 ORIGINAL COMMUNICATIONS. tion, till the citadel of life itself shall be overmastered and overthrown. * ARTICLE III. ExPULSEoN of A ToAD FROM THE ALIMENTARY CANAL.-BY JNo. BRY ANT, J.R., M. D., INDEPENDENCE, M 9. Julia R—. age 9 nine years, had been complaining of headache and general malaise for two weeks or more; no appetite; bowels rather constipated. Her mother fearing typhoid ſever sent for me on the 7th of April. I found her as above, also with leucorrhoea, no fever. The leucor- rhoea and general symptoms induced me to diagnose the case as one in which those small worms (ascaris vermicu- laris) were irritating the rectum to such a degree as to produce the leucorrhoea. I ordered a dose of oil and tur- pentine next morning, with directions to watch for the worms at ever stool, and to let her have stools in a vessel in the room. This dose, as the father told me, brought no worms. I then ordered a repetition of the dose next morning. This produced a passage which pained her so much she cried; when she rose from the vessel she ob- served she had passed something large and dark which so frightened her as to render her very nervous, or, as the Inother states, she trembled, for some little time. The passage of this created slight hemorrhage. Her mother sent the specimen to me immediately to know what it could be. I found it to be the skin and bones of a full grown toad, with contents wanting. She was soon well after this, Now how this little patient could have swallowed the toad without knowing it, is a mystery to me; she insisted she knew nothing of its entrance. She has more than usual intelligence, and, will render me all the assistance-in her power to diagnose any ailment she has. I will state that the rains in February and March rendered the water 11 at school slightly muddy, but not enough I think to hide a toad. The vagina was examined directly after its pas- sage, showing no irritation there. It passed through the alimentary canal and was digested except skin and bones. It also must have been several weeks in passing, for she complained so long. How did it get there P ARTICLE IV. THERAP EUTIC PROPERTIES OF AMMONIUM CARBONATE.—BY W. A. JACKMAN, M. D., Ito CHEPORT, MO. Ammonium Carbonate has never been used as far as my knowledge extends until late years, except to fulfill cer- tain indications in the advanced stages of disease, upon the supposition that its value depended solely upon its stimulant properties, and thus aided in sustaining the vital powers in cases where there was extreme prostration. It was advised simply as an auxiliary to other measures, and recommended as a stimulant in all low forms of disease without reference to other indications. That it is a valua- ble stimulant to the heart and arterial system—perhaps as much so as any drug we possess—I believe; but that the older writers did not fully understand its therapeutic value I am well convinced. I am satisfied that this application of the remedy is far too limited, and that its stimulant properties constitute but a small proportion of its remedial value. They would have regarded a man unworthy a place in the profession who, a half century ago, in the days of bleeding and tartar emetic, would have recom- mended a powerful stimulant in the acute stage of a highly inflammatory disease. This, however, is but an evidence of the revolution that is continually going on in both theo- retical and practical medicine, and of the contrariety of opinion with reference to the treatment of disease among medical men. - That there is great want of uniformity of method of treatment, even among those who practice the same system ! 12 ORIGINAL COMMUNI CATION S. as to constitute it an approbrium medicorum, none will deny who read medical works, and attend the meetings of med- ical societies. Theory, correct theory, is all important in the practice of medicine, but what the practical medical man wants, and the afflicted need, as a result of investiga- tions by physicians, is unerring truth, axioms which when reduced to practical application will be found as exact as it is possible to attain in medicine. The effect of a remedy in its application to disease is one of the most important things to be considered by the physician, and this can only be learned at the bedside. To attain to something like certainty in practical medicine should be the aim of every scientific and conscientious physician, and our first inquiry should be, upon what coſt- dition of the human system does each disease depend; what is its cause 2 And secondly, what remedial measure is best calculated by its #nown properties and effects upon the human organism to remove the abnormal condition ? Accuracy of observation is the first duty of the physi- cian, for it is by the daily continued practice of accurately observing disease, and the effects of remedies in our clin- ical experience, and recording them in book form, that has contributed to advance practical medicine to its present honorable but far from perfect condition. It is well under- stood and generally admitted that the study of disease in its special pathology, etiology, symptomatology, and thera- peutics, constitute the only true rational and scientific method of advancing practical medicine. What then is the chief therapeutic value of the remedy under consider- ation ? It is believed to be the best defibrinizer of the blood we have, and there are not wanting well educated and scientific physicians who believe that it comes nearer being a specific—if it be possible to attain to such a thing in medicine—than Quinine as an anti-periodic. But in order to a correct understanding of the subject, it will be necessary to briefly discuss the pathological condition present under certain morbid conditions of the blood, or AMMONIUM CARIBO NATE. 13 rather one of its organic elements, to-wit: fibrine. Now, I do not propose to go back into the past and discuss the truth or falsity of either the solidist or humoral pathology; but believe it to be the duty of the physician to ascertain as far as possible, preparatory to the treatment of disease, the morbid condition present, and if possible the cause of said condition. But what is fibrine, and what is the pa- thological condition when morbidly increased or decreased? Fibrine is that portion of the liquor sanguinis or blood- plasma, which solidifies, forming the coagulum or clot observed when a quantity of blood is drawn into a vessel and allowed to stand a short time. Certain of the phe- nomena pertaining to the coagulation of the blood without the vascular system are important in their pathological re- lations, and might not be void of interest in this discussion; but the limit allotted to this paper forbids a further refer- ence to it, than to add that the buffy coat and cupped | blood formed the base of the therapeutics of our fathers in medicine; and believing, as long as they existed, bleed- ing to be the great remedy, persisted in the withdrawal of the vital fluid from the vessels; not knowing as we now do that, as venesection increases the fibrine and diminishes the globules, the more they bled the worse the trouble. Next we wonder at the perfect revolution in the pro- fession with reference to venesection. But their premises being false, their deductions drawn therefrom could not well be otherwise, hence the conclusion that their thera- peutics were erroneous. Hyperinosis—so called by Si- mon—constitutes that condition known as an abnormal increase of fibrine in the blood; the average proportion of which in health is about two and a half parts in one thousand. This condition characterises acute inflamma- tions. In different cases of acute inflammation the in- creased proportion is found to vary from three to twelve parts in one thousand. Acute articular rheumatism pre- sents the largest increase of filbrine; pneumonia ranks next with reference to that feature, and capillary bronchitis 14 ORIGINAL COMMUNICATIONS. next. But coagulation within the vascular system—insep- arably connected as it is with our subject—I propose briefly to consider in this connection, as it is known to take place during life in the cavities of the heart and ves- sels. Certain concretions, or in other words small coag- ula, consisting of fibrine are found deposited on the valves and at the orifices of the heart. This may take place as a result of the exudation of lymph, or the deposit of calcareous matter; but doubtless occurs also when the blood is surcharged with fibrine as in acute articular rheu- matism. It likewise occurs in endocarditis under similar conditions. - - These coagula are oftener found in the left cavities of the heart as the result of two causes; first inflammation and valvular lesion are of more frequent occurrence in these than the right cavities; and secondly, arterial blood contains more fibrine than venous blood. These fibrinous deposits may accumulate and form masses as large as a bean, or even much larger, and occasion obstruction in proportion to their weight and volume, and sometimes torn off by the current of blood, thus constituting em- boli or plugs, and being carried along the arteries with the flow of blood at length reach a situation where the size of the vessel prevents their further passage, Thus arrested, the first effect is the obstruction to the flow of blood to the parts supplied by the vessel, and may thus give rise to important pathological effects dependent on its sudden in- terruption; resulting secondarily in apoplectic seizures and paralysis in a cerebral artery. An ulterior effect of embolism in the cerebral arteries is softening; and in other parts gangrene may be a result of the continued deficiency in the supply of blood. These coagula which are found after death fixed in the arteries of the brain and elsewhere, are found to be simi- lar in their miscroscopical characters to co-existing fibrin- ous deposits within the cavities of the heart. A second variety of embolism, termed thrombi, occurs when the *: AMMONIUM CARIBO NATE. - 15 * ºmºsºme a mºme plugs are derived from the veins, though upon this variety we cannot amplify. It will readily be seen, however, that emboli formed in the left cavities of the heart and arteries, produce obstruction in the arterial circulation; whereas, the emboli—or rather thrombi—formed in the veins, pro- duce obstruction in the pulmonary circulation. Sudden death may be produced by a clot sufficient to cause plug- ging of the pulmonary artery, and local inflammation with suppuration may occur from the smaller masses in the branches of this artery. In this Virchow explains the occurrence of multiple abscesses in the lung in cases of pyaemia. - Embolism belongs among the more prominent modern discoveries relating to the nature and source of morbid condition. Much attention has been directed to it in re- cent years, and facts are constantly accumulating which tend to show the importance of the subject, both patho- logically and practically. Coagula are usually found in greater or less abundance in the cavities of the heart after death, and are in general formed after death or during the act of dying; but are sometimes formed during the progress of disease; and a sudden and unexpectedly fatal terminationin in certain cases, are due to their formation. In pneumonitis for in- stance, it occurs not very infrequently, owing to the high degree of hyperinosis, producing obstruction to the pul- monary circulation. The sudden occurrence during the progress of a disease, especially the one first mentioned, of great irregularity and febleness of the heart's action, attended with anxiety, oppression and great dyspnoea— death taking place after a few hours from the notable change in the symptoms, and no other cause for the change being apparent—should lead to a strong suspicion of this accident. Perhaps there is no physician of experi- ence who has not met with this accident in his early ex- perience, but was then unable to account for the sudden fatal termination of the disease, The liability to this acci- 16 oRIGINAL communications. dent in diseases where there is a high degree of hyperinosis suggests the inquiry whether measures to guard against its occurrence are available. The fibrine in its normat state is a liquid, but why that is so has long been an ob- | scure question with physiologists. The preservation of | that liquidity, or in other words to prevent its coagulation | within the heart and blood vessels, presents an important | pathological consideration, suggesting to the observant | physician valuable therapeutic indications. From a large number of experiments made some years ago by a distinguished physician–Dr. Richardson, of London—the conclusion has been drawn that it is due to | ammonia in the blood. Accepting this explanation as probably true, ammonia has been given as a remedy with a view to maintain the liquidity of the fibrine in the blood, in cases where there may be reason to fear the formation of heart-clot. Will it accomplish this object? There are not wanting many who believe that it will, and so far as it has been tested has been abundantly established; and if indeed on further trial it is confirmed, it will readily be conceded that its remedial value has been greatly under- rated, and that it is the sine qua non in the treatment of a certain class of diseases. I think, however, it will be found to be best adapted to the treatment of diseases of the pulmonary organs, as capillary bronchitis, pneumonitis gangrene of the lungs, &c. But allow me to ask by way of eliciting information, why it might not be a valuable remedy in acute articular rheumatism P For the blood is known to be surcharged with fibrine in that disease, re. Sulting in its deposition in the heart and blood vessels with its resultant evils. It is now being given, and has been for quite a number of years, with a success that commends it to the consider- ation of all, especially in pneumonitis; a disease which, if published statistics are to be relied on, was alarmingly fatal under the old treatment of venesection, powerful sedatives, &c., &c.; the mortality being under the treat- AMMONIUM CARBONATE. 17 ment of Rasori as I in 2%. In contrast with this let us compare the results of the method of treatment here ad- vocated. One physician, a man of age, of large experince, fine attainments and comprehensive views, reports the loss | of two cases only out of ninety-six well marked bad cases, | treated on the ammonia plan; nothing else being given after opening the bowels with a mild laxative. No alco- holic stimulants were allowed in any stage; quinine was given to control malarial complications, or as a tonic in the fast stage only. He treated over two hundred other cases on the mixed plan, giving alcohol and ammonia, sedatives, as tartar emetic and veratrium, with quinine, throughout | the disease, with variable success. Another physcian re- gards it as “decidedly the most effective plan,” having treated “72 cases with a loss of two only.” Another re- | ports 78 cases treated, 35 of which were treated on the | ammonia plan with one fatal result; the remaing 43 were treated on the old plan with all the remedies usually given, | with four deaths. Another still gives as his experience in one year, one fatal case out of 73; in six months, the year following, 33 with the loss of two. These results certainly commend themselves to our se- rious consideration in comparison with the former plan, as the experience of respectable practitioners, all of whom certainly could not have been mistaken; indeed one of them says his observations had been extensive and care- fully made. This treatment certainly gives the most favor- able results of any method yet presented to the profession. These observers tell us that under the use of this remedy the febrile excitement, heat of surface and temperature are reduced; the skin becomes moist; the pulse becoases less frequent but full and strong; that the respirations are likewise rendered easy, regular and less frequent. It also diminishes the viscidity of the sputa, promotes expectora- tion, and the oxygenation of the blood; and by relieving the hyperinosis prevents many of the complications liable to occur during the progress of the disease. 18 ORIGINAL COMMUNICATIONS. They also tell us that if given “early in the disease, and regularly in full doses, it will in almost every case so limit the exudation process as not only to greatly lessen the amount of hepatization, but to insure a prompt and rapid absorption of the exudation, and occasionally it will entirely prevent hepatization, and terminate the inflam- mation by resolution.” Whether this remedy will ac complish all that is claimed for it above, future, ob- servation alone must determine, but upon the points claimed they cannot be mistaken. My experience with it is perhaps limited in comparison with some but I have ! been using it for some time, and my success with it has inspired me with confidence in it as a remedy of great | value. ARTICLE V. A CASE OF MAILFORMATION REPORT FD TO THE LINTON DIS- TRICT MEDICAL ASSOCIATION AT THE APRIL MEETING BY W. F. HuMPHREYs, M. D., of Concord, Mo, The monstrosity represented by the above cut was born in Callaway county, Mo., on the 9th of February, 1877. The parents are in robust health, and of the first respecta- bility, and have two finely formed healthy children. The "| age of the mother about twenty. There was nothing um- usual during the period of gestation nor until labor had fairly set in ; the movements of the child being distinctly felt. Dr. Baker, of McCredie, who was in attendance, finding a shoulder presentation, administered Chloroform —r— MAIL FORMATION. 19 and delivered by turning, the child showing no signs of life. - I saw and examined the child a few hours after birth, but unfortunately an autopsy could not be had. DESCRIPTION.—Above the Umbilicus the development was in all respects perfect. The cord was small and not in the median line; the abdomen was quite prominent and there was a gradual tapering to the end of the single lower extremity. The Pelvic bones were not so developed as to enable me to distinguish any of them ; there was neither crest of the Ilium nor Pubic Arch. The lower extremities were not differentiated; there was one broad Os Femoris that formed apparently a hinge joint with the lower extremity of the Sacrum; its length was the normal length of the thigh. The articulation correspond- ing with the knee was apparently destitute of Patella and flexed forward instead of backward. One broad bone took the place of the Tibia and Fibula. If there was a gastrocnemius muscle it could not be determined which side of the leg it occupied. Below the ankle there was no development of bone, but an appendage of integument, cartilage and muscle, bearing about as much resemblance to a foot as a moccasin does. While the natural position of the extremity seemed to be that represented in the cut, it could be extended almost to a line with the body. There was no appearance of an effort to develop either Anus or Genito—Urinary organs; consequently there was no outlet from bowels or bladder and no place for them. QUERY.—Does this case, showing as it does a tendency to retrograde, confirm the Darwinian theory of progress- ive development P 20 O RIGINAL COMMUNICATION S. ARTCLE VI. As OTHERS SEE Us.--BY G. WILEY BRoom F., M. D., Mors- ERLY, Mo. If we should open the ledger and compare the contribu- tions made to the Surgery of our country with those added by the profession of other states, how would the ac- count stand P Let us see. The first known amputation at the hip joint belongs to Kentucky, performed by Dr. Walter Bradshaw of Nelson county, in 1806. In Hartford, Ohio county, Ky., the dar- | ing and hazardous operation of removing the entire clav- icle was successfully performed for osteo-sarcoma by Charles McCleary, M. D., on the 4th of May, 181 I. To Ephraim McDowell, then of Danville, Ky., is the world indebted for an operation performed in the well known case of Mrs. Crawford, of Danville, in December, 1809—-the removal of an Ovarian Tumor; an operation now performed all over the civilized world to the saving of thousands of lives, before which time they were doomed to a lingering death. John Briggs, Jr., M. D., has priority for the operation of extirpating the Uterus at Bowling Green, Ky., in 1830. The pioneer in Lithotomy, and who operated an hun- dred times without a death or failure, was a Kentuckian— Dr. Benjamin W. Dudley. In Tennessee, in February, 18 IO, without known prece- dence or professional counsel or aid, Dr. W. H. Deadrich successfully removed nearly one-half of the Inferior Max- illary bone from a lad of fourteen years of age. The patient fully recovered. This was the first operation of the kind ever performed. It was in Tennessee, in Rutherford county, that intus- susception was successfully relieved by Gastrotomy by Dr. John R. Wilson, in December, 1831. The report says of this wonderfully skillful and hazardous operation: “Other means having failed, seventeen days after obstinate obstruction in the boweſs, the abdomen was opened by an AS OTHERS SEE U.S. 21 ºmºmºmºsºms smºsºmsºmº incision two inches above and three below the umbilicus, when the Ileum was found invaginated and threatened with mortification ; it was drawn out carefully and relieved. The wound was then closed with sutures and plasters and the patient soon voided the mercury he had taken the night before.” In the city of New Orleans, La., in the year 1831, Dr. Charles Luzenberg laid open a strangulated hernia and finding the intestines completely mortified did not hesitate to remove six inches of dead intestines, stitch the serous surfaces together, and the patient fully recovered in 35 days. The first successful excision of the Ulnar and Ra- dius was performed in New Orleans by Dr. Compton in I833. *. The first and probably the only successful removal of a kidney was performed by Dr. G. T. Gilmore, of Mobile, Alabama. In Alabama the distinguished J. Marion Sims, now of . New York City, first established the curative treatment of : Vesico-vaginal fistula. It is generally conceded that Dr. Nott, of Mobile, Ala., first suggested the removal of 2 or 3 segments of the Os coccygis for an otherwise intolerable coccydynia in 1843. Prof. G. C. Blackman and those living before and cotem- poraries with him have done much toward improving the art of surgery. But it is a fact everywhere conceded, we must acknowledge, the greatest number of original and brilliant exploits in surgery have been inade in small towns, and more particularly at the south. Now in comparing our account with valuable surgical contributions made by other states, must it be confessed that the leaf set apart in this ledger for original contribu- tions from the surgeons of Missouri does not have a single case of originality recorded upon it 2 It is true that Hodgen for his modification of Smith's anterior wire suspension splint; for his modifications in the operation for lacerated perineum; for his simplification 22 SELECTED. of all appliances in surgery, and his eminently practical teachings; that Dr. Hammer, amongst other creditable surgical operations, for his excision of the scapula; that Joseph Wood for his wonderſul success in Lithotomy, de- serve the highest commendation. But for unprecedented exploits and brilliant triumphs in surgical practice the surgeons of Missouri are wanting. This is a fact and it may give us renewed earnestness and a jealous ambition to endeavor to deserve a share of the honor in promoting the advancements of the triumphs in Surgery. SELECTED. MA f, ARIA.(*)—BY CHARLEs P. RUSSELI, M. D. The terms malaria and miasm in medical phraseology include the causes of a large class of affections—what are known more particularly as 2/motic diseases, which depend upon a variety of specific organic poisons whose essential nature, composition and form are most inappre- ciable as yet by scientific research, The general under- standing, however, of these terms is more limited; and, in conformity with the popular idea, I shall in the present paper confine their application to the cause of those wide- spread disorders, intermittent and remittent fevers--the former of which is so well known as “chills and fever” or “fever and ague.” -* (*) A po; .ion of a paper read before the New York Public Health Associa- tion, April 13, 1876. S I LECTIED, 23 “Time out of mind,” as Watson remarks, “it had been matter of common observation that the inhabitants of wet and marshy situations were especially subject to these definite and unequivocal forms of disease.” The same natural agencies which are at work elaborating, evolving, and dissemminating malaria must have been equally in operation ever since the surface of the earth assumed its present condition. Vast and remote wildernesses that have never known human presence teem, as of yore, with deadly exhalations that almost preclude the bold attempts of enterprising men to lay bare their secrets. There are some parts of India, as Bishop Heber informs us, which even monkeys and other wild animals instinctively desert between April and October of each year. The tigers go up to the hills; the antelopes and wild hogs make incur- sions into the cultivated plains; and those persons, such as dać-bearers and military people, who are obliged to venture into the marshy jungles, agree that not so much as a bird can be heard or seen in the frightful soli tude. The celebrated Pontine Marshes may be regarded as the classic home of malaria. The older historical records describe this tract as occupied with numerous towns by the Volsci. It was evidently a fertile region; for we read in Livy that the early Romans sent thither during a season of scarcity for a supply of corn. Three hundred and twelve years B. C., the Censor Appius Claudius Caecus constructed the Appian Way across the length of the Pon- tine region, the soil of which must have been sufficiently compact to support the heavy causeway. At some period of the subsequent century and a half, the country seems to have undergone great deterioration either from natural or civil causes, and to have become partially inundated; for, abount I70 B.C., we find the Consul Cornelius Cethe- gus applying himself to draining the marshes, and restor- ing the land to cultivation and salubrity. The result of his efforts was, that new and flourishing towns arose on 24 SELECTED. the ruins of the ancient Volscian cities. The civil wars, however, and the devastation which accompanied them, again caused the hydraulic works of Pontine Marshes to fall into neglect, until they were repaired by Augustus, who constructed several new canals, especially a navigable one skirted by the Appian way. It was on this canal, at Forum Appii, that Horace embarked one evening, and at the same spot St. Paul first met his countrymen from Rome. Nerva and Trajan both contributed to the drain- age of the Pontine Marshes, and left inscriptions, still ex- tant, which testify to their great interest in the project During the convulsions of the following centuries they were overflowed anew, until in the reign of Theodosius they were once more drained, with most beneficial effect, by a public-spirited individual named Caecilius Decius. We have no subsequent account of the condition of this region until the end of the thirteenth century, when Pope Boniface VIII constructed some works to drain it. Leo | X employed the engineer Giovanni Scotti to repair and enlarge the canal of Badino, the principal outlet of the marshes, and Sixtus V. built a large lateral canal. The | most important improvements, however, were effected by | Pius VI, and a system of effectual drainage was almost completed, when the low condition of the papal treasury and the confusion attendant upon the French revolutionary invasion completely arrested the undertaking, which up to that time had involved an expense equal to $1,622,000. No new works have since been attempted, although the authorities endeavor to keep the canals clear and the dikes in repair. The greater part of the plain is covered with rich pastures; but, except the post-stations along the highway, and some scattered huts of herdsmen, it has and can have no permanent population. Taking the United States census of 1870 as a guide for our own country, we find malarial fevers forming a very important feature of the mortality-tables. They are most fatal in Florida, Louisiana and Texas. Next in order fol- SELECT ED. 25 -*- low Arkansas, Mississippi, Alabama, Georgia, Missouri, Kansas and Nevada. In another group distinguished by a somewhat less mortality we find New Mexico, the Caroli- nas, Virginia, Tennessee, Kentucky, Illinois and Indiana. Those states marked by the lowest mortality are the New England and Middle States, Wisconsin and Minnesota. In California there is a considerable ratio of mortality, di- minishing easterly in Utah, and northerly in Oregon and Washington Territory, while it augments largely toward the south in New Mexico. Since the census was taken, however, that is, since about 1869, there has been noticed an evident extension of the subtile miasmatic agency over regions previously exempt from it in the Middle and New England states. The increase of mortality by this cause in New York City has been notable, but can scarcely be attributed entirely to local influences. In 1868 there were registered in this city only 98 deaths from malarial fevers. In 1869 they rose to 128; in 1870, to. 21.3; in 1871, to 291 ; and in 1872, to 348; an increase of 350 per cent. in four years. Since then some diminution in their fatality has occurred. They occasioned 282 deaths in 1873, 295 in 1874, and 275 in 1875. Let us now consider under what circumstances malaria may be produced. Although it cannot be denied that there are peculiar localities where, with apparently every presumed condition existing for the development of mala- ria, that poison is entirely absent, yet the concurrence of malarial emanations with such conditions in innumerable places establishes beyond a question their direct relation." The essential element in the production of malaria would appear to be vegetable decomposition, and, in order that this process shall ensue, the simultaneous operation of air, moisture, and a certain high range of temperature, is abso- lutely required, Localities, therefore, where such com- bination occurs, are prolific of malaria. Of this character are swamps and morasses, alluvial deposits, loose, porous, 26 - - SF I, ECTIED. -ms- sº- sandy, and argillaceous soils, loamy, marly lands under- laid by impermeable strata affording capacity for the reten- tion of moisture, regions exposed to periodical or occa- sional inundation, places left bare by the subsidence of | lakes or drying up of streams, and particularly areas sub- ; ject to the intermingling of salt and fresh water—as, salt- | marshes into which fresh streams discharge, or regions liable to tidal overflow and recession. - The exhalations from marshy tracts are recognized by their effects upon the human system throughout the world; and the fact that marshes bear a causative relation to malaria has been demonstrated in numerous instances 4. by the disappearance of fever after thorough drainage and cultivation, and its reappearance upon their being allowed to relapse into neglect. The favorable effect of drainage and cultivation is owing both to the systematic removal of water near the surface and most probably also to the ab- sorption by the growing crops of the products of organic decomposition. On the same principle Prof. Maury suc- ceeded in antagonizing the noxious emanations from a marsh surrounding the observatory at Washington by planting it thickly with sunflowers, which seem to possess an extraordinary absorbing power. Sebastian is inclined to believe that the calamus aromaticus which grows in some swamps has a similar neutralizing quality. Swamps covered with water are not so dangerous as those partially | dry, the layer of water serving as a protection against the | actess of air and heat to the vegetable matter underneath. A certain continuous range of temperature seems essen- tial to the development of malaria, which is almost un- known beyond 60° north and 57° south latitude, and dur- ing the cold season in the temperate zone. According to Hirsch, it prevails up to various degrees of latitude and average annual temperature. It is the average summer temperature, however, that is of account, and the northern limit of this lies between the isotherms of 59° and 59.8° -;|| :. SEI, ECTED. 27 | Fahr., giving a prolonged temperature sufficiently high to insure vegetable decomposition. The alluvial soil along the banks of rivers and at their deltas, as those of the Ganges, Nile, Orinoco and Missis- sippi, gives rise to fevers of a very malignant type. Their banks are subject to overflow, and frequently have a clayey subsoil, presenting an obstacle to percolation—thus upon the river's receding into its ordinary channel its banks remain damp below the surface, and disease is generated by the Sun's agency. A like process annually takes place in the extensive plains and table-lands formed of alluvium washed down from naountain ranges during the lapse of centuries, and having few actual marshes. Profuse rains, succeeded by dry, hot seasons, render such regions exceedingly insalubrious during certain periods of the year. Somewhat similar in characteer are the oases of the JDesert of Sahara, which abound in malaria. Hirsch describes these spots as consisting of trough-like depres- sions in a rocky or highly hygroscopic soil, the receptacle of subterranean waters, and covered with a layer of allu- vium, the surface of the oasis. In this the fierce heat of the sun causes cracks and deep rifts in the earth, which give free vent to the miasm evolved from beneath. Sandy plains, especially when at the foot of tropical hills and covered with vegetation, as the “Terai” at the base of the Himalayan range, are often infested with ma- laria. In other cases sandy plains at a distance from hills, apparently dry and not subject to variations in the ground- water, are equally sources of the poison. Such instances as the latter might seem to militate against the generally accepted theory, but actually do not. Some sands which appear quite free from organic admixture are really the reverse. Faure has pointed out that the sandy soil of the Landes in southwestern France contains a large amount of organic ingredient which is constantly decomposing and gives rise to periodic fevers. Under such sands, % 28 SELECTED, moreover, there is frequently a subsoil of clay. Here, then, assuming a continued high range of temperature, we find all the conditions necessary for the production of malaria. Localities subject to the intermixture of salt and fresh water are particularly prone to malaria. The Maremmas of Italy afford examples of this on a large scale. The Maremma of Lucca consists of three basins formerly dotted over with ponds and pools. It had been for cen- turies frequently overſiowed by the sea-tides which inter- mingled with its fresh ponds. Malarial fevers ravaged it and rendered it almost uninhabitable. To the wayfarer who was so imprudent as to spend a night of August or September within its desolate bounds, the penalty was al- most certain death. A remedy for this deplorable condi- tion of things was long sought. A proposition had been made in 1714 by the engineer Rondelli to attempt the ex- clusion of the sea. Renewed in 1730 by Muanfredi, and Six years later by Zendrini, a mathematician of Bologna, the idea was finally carried into execution in 1740. The initial step was made upon the principal and most un- healthful basin. A sluice was constructed at the entrance of the canal of Burlamacca through which the waters of the sea penetrated into the basin to its central pond, The flood-gate was so arranged as to act like a valve, shutting by the pressure of the rising tide and opening when it fell. The success of this enterprise was so complete that in the miasmatic diseases which had never failed to show them- selves annually did not reappear, and the whole district was rendered salubrious. It was at this period that the village of Viarregio, previously abandoned and composed only of a few fisher's huts grouped at the foot of an old tower where galley-slaves were confined, became a place of fashionable resort during the summer for the aristocra- cy of Lucca. This fact of a region's being rendered healthy by the exclusion of sea water is curious, but made more decisive still by its counter-proof. In 1768-’69 fe- SEI, ECTED. - 29 vers suddenly sprang up again as bad as ever in the same territory. Upon the cause being investigated, it was found that the sluice had become deranged and the mixture of waters had been reestablished. Upon the flood-gate being repaired, the malaria was again extinguished. The same occurrence happened in 1784-'85. The sluice having been neglected, there took place in 1784, out of a population of I,900, the enormous number of 1,2OO cases of malarial fever and 92 deaths. In the following year there occurred IO3 deaths. The trouble was remedied in the same man- ner as before. The other portions of the Maremma were rendered healthy later by sluices successively established at different points. Such a remarkable result necessarily attracted public attention. Leopold II, Grand-duke of Tuscany, was particularly impressed by it, and he con- ceived the great idea of improving the whole Tuscan Maremma in the same manner. It was an immense un- dertaking which he contemplated—an actual transforma- tion of a large part of his dominions—and it redounds to his glory that he succeeded, in the face of almost insur- mountable obstables, by the means described, and a prop- erly directed system of canalization and field-culture, in regenerating a very considerable portion of his territory. It is not difficult to account for the generation of mala- ria under such circumstances as those just mentioned. The minute forms of vegetable life with which both fresh and salt water teem require their own special element for continued existence. The intermixture of salt with fresh water introduces a new element with which the life main- tained in each separately is incompatible. The surface of the soil consequently after every invasion and retirement of the tide exposes to the action of the heat a mass of de- funct vegetable material spread out over an extensive area, and in most favorable condition for speedy decomposition. Besides the localities enumerated, malaria is apt to be induced or intensified in a region wholly or comparatively exempt from it before, during the disturbance of large ex- 30 SELIECTEJO). tents of soil, as in the construction of canals, roads, rail- ways, fortifications, and dikes, rooting out of timber, prep- aration of virgin land for cultivation, etc. Vegetable or- ganisms previously hidden and protected underground are thus brought to the surface and exposed to the agencies of putrefaction. Laborers engaged in such works and the neighboring inhabitants soon suffer. The “polders” of Holland, those parts reclaimed from the sea by the erec- tion of dikes, are of this character, and the workmen en- gaged on them are attacked with malarial troubles of great severity. In this country such instances are com- mon. We have an example at our very doors in the in- crease of malarial fevers which accompanied the opening of the new boulevards, and the engineering excavations of the Harlem railroad. After such works have been com- pleted, however, it is not unusual for the vicinity to be restored to healthfulness. It must be acknowledged that occasionally miasmatic fevers appear and disappear with- out there having occurred any perceptible changes in the relations of the soil. Such circumstances were reported to the Pennsylvania State Medical Society as having been noticed in 1855 along the Juniata river. Reports to the Connecticut State Medical Society also mention the ap- pearance of Miasmatic disorders without any recognized cause in portions of the state previously exempt from them. There would appear to be some connection between such phenomenu and the fluctuating level of the subsoil- water as affected either by rainfalls or subterranean forces. According to Jilek's figures, in Pola, a noted malarious district of Istria, between 1863 and I 868 the number of persons attacked by fever varied from fourteen to fifty-one in every one hundred inhabitants, in exact proportion as the rainfall had varied from one to eighteen inches. We know that the level of the ground-water is con- stantly changing. It rises and falls more or less rapidly, and at different rates in different places—in some only a SELECTED. 31 *meºsºmsº ..few inches either way annually, but in many places several feet. In Munich, its limit was found by Pettenkofer to be about ten feet. In India the changes are greater. At Saugor, in central India, the extremes are between a few inches from the surface during the rains, to seventeen feet in May. At Jubbulpore it varies from two to fifteen feet from the surface. The causes of such changes are rain- falls, pressure of water from seas or rivers, and obstruction of outflow. The pressure of the Rhine has been observed to affect the water in a well 1,670 feet distant from the river. An impeded outflow which raises the level of the ground-water has been productive of an immense spread of paroxysmal fevers. Demster, Taylor and Ferguson have reported such to have been the case in portions of India. The severe and fatal fevers prevailing in Burdo- wan, Lower Bengal, during the last fifteen or twenty years, have been coincident with obstruction to the natural drainage from mills and blockage of water-courses. The same cause has doubtless operated to a great extent in producing the fevers of Bloomingdale, Manhattanville, Yorkville and Harlem. The establishment during the past five years of extensive subsoil drains in those por- tions of New York has had a visible tendency to diminish the area of malaria. A similar result on a large scale has been noticed in Lincolnshire and other parts of England, where many malarious tracts have been rendered quite healthy by similar measures, having for their object the lowering of the subsoil water-level by an increased out- ſlow. I have thus far confined my observations to endemic malaria. But, like other diseases dependent upon telluric or organic emanations, miasmatic fevers occasionally as- sume an epidemic character, and, breaking loose from their native haunts, overspread a wide extent of territory. Thus, as Hertz informs us, nearly the whole of Europe was invaded by such epidemics in 1558—in 1678-79– from 1718 to 1722—from 1824 to 1827—and from 1845 3.2 SELECTED, to 1848. The cause of malaria being thus propagated is, as mysterious as that of most epidemics. It is possible that such an epidemic malarial influence has been prevail- ing here; but we must not lose sight of the fact that sporadic cases of malarial fever appearing in non-malarial districts can frequently be traced to previous exposure in an infected locality. - Malaria, although having its ordinary habitat in low- lying regions, may under conditions favorable for its pro- duction exist at great elevations. On the Tuscan Apen- nines it is found at a height of I, IOO feet above the sea; on the Pyrenees and Mexican Cordilleras, 5,000 feet; on the Himalayas, 6,400 feet; on the island of Ceylon, 6,500 feet, and on the Andes, I I,000 feet. Sometimes, however, at considerable elevations it is unaccountably absent under circumstances apparently supplying every condition for its development. Thus, according to Jourdanet, close to the City of Mexico lies the lake of Tuscudo, some twenty-five square miles in extent, composed partly of fresh and part- ly of brackish water, with a clayey bottom often laid bare over large areas as the result of evaporation under a tem perature of 122° Fahr., notwithstanding which, malarial fevers seldom occur in its vicinity. At Puebla, Mexico, on the other hand, is a very malarious marsh 5,000 feet above the sea. Under ordinary circumstances, a certain altitude affords immunity from malaria, although low ele- vations of 200 or 300 feet above a miasmatic tract are often more dangerous than the flat lands—the poison seeming to float upward and become intensified. This was long noticeable on the heights of Bergen Hill, West Hoboken, and Weehawken, which overlook the Jersey flats. At present, the elevation of entire security is not positively determined, but it has been approximated as fol- lows: In Italy, 400 to 500 feet; in California, 1,000 feet; along the Appalachian chain of the United States, 3,000 feet; in the West Indies, 1,400 to 1,800 feet; in India, SEI, EC 1. ED. 33 2,000 feet. In any of such regions, however, may drift up ravines to an indefinite height. The agency of winds in transporting malaria for considerable distances cannot be questioned. Lancisi, author of the famous work “De Noxiis Paludum Effluviis,” published in Rome in 1717, attributes to such influence the fact of the Roman Cam- pagna having become unhealthy after the removal of the sacred groves exposed it to the currents of wind blowing from the Pontine Marshes. In later years, Barat accounts in the same manner for an epidemic of malarial disease which arose in 1869 on the island of Reunion, believing the poison to have been transported by the wind from Mauritius, where such affections were then alarmingly prevalent. In this instance none of the ordinary local causes could account for the outbreak. In four months over 4,000 cases occurred in a population of 23,OOO. Sal- vagnoli and other observers affirm that malarial diseases increase in intensity, and penetrate further inland on the island of Sicily and in South Italy during the sirocco laden with African miasm. . With regard to the question, “Can drinking-water act as a vehicle for the introduction of malaria into the animal system?” a priori it seems reasonable to suppose that such may be the case. If malaria, be it a gaseous substance or an accumulation of minute organisms, cannot pollute water, it differs essentially from other materials of similar form with which we are better acquainted. But, in fact, we have positive proof that malarial fevers may be due to drinking impure water. Mr. Bettington, of the Madras civil service, states that in that country it is notorious that the water may produce miasmatic fever and affections of the spleen. He mentions villages placed under similar conditions as to marsh-air, in some of which fevers are prevalent and in others not—the difference resulting from the former drinking marsh-water and the latter pure water. In one village there were two surces of supply—a | tank fed by surface and marsh-water, and a pure spring ; 3 4. SH, I, FC"l'Eſ). *-* *-* only those who used the tank-water contracted ſever. The Celebrated instance related by Boudin is still more conclu- sive on this point. In 1834 there returned to Marseilles from Bona in the ship Argo I2O soldiers, of whom Iog were seized with various forms of malarial fever after drinking marsh-water taken on board at Bona. On the other hand, the sailors of the same vessel, who had pure water, and 780 men embarked on two other vessels, re- mained well. The few soldiers on the Argo not attacked had purchased their drinking-water from the sailors. Against such positive evidence as this the statement of Finke that in Hungaly and Holland marsh-water is drunk without injury is of little value. Now, a number of careful investigations have been made of the constituents of miasmatic marshes in various parts of the world, with the following results: They contain from thirty to thiſ cy-five per cent. of vegetable organic matter. This consists of humic, ulmic, cremic and apo- cremic acids, all substances requiring renewed chemical investigation. Various minute vegetable algoid forms are revealed by microscopic examination—bacteria, vibriones, and microzymes. But all these so-called impurities are found in nearly every running stream and in many harm- less well-waters, and to condemn water on account of their presence would be really to reject all waters, even rain, in which minute algoid vesicles (protococci) are often found. Even distilled water may contain bacteria and vibriones. Although, therefore, admitting that water may be contam- inated by the presence of malaria, it by no means follows that this poisonous ingredient has any relation to the organic impurities mentioned, or that the latter are in any way injurious, but we should none the less be cautious as to the source of our drinking-water. The stratum of air overlying typical malarial marshes has also been examined with particular care. It has bcen found to contain an excees of carbonic acid—watc1y va- por in large quantity—often carburetted hydrogen, and SELECTED. 35 occasionally free hydrogen, ammonia and phosphuretted hydrogen. If the marsh contains sulphates, sulphuretted hydrogen is present. Its organic matter blackens sul- phuric acid—-gives a reddish color to nitrate of silver— has a flocculent appearance, a peculiar odor, and affords evidence of ammonia. The amount in Becchi's analysis was .oOOI 18 grain in each cubic foot of air. Ozone had no effect upon it. Besides this organic material, various vegetable and animal matters are arrested when the marsh- air is drawn through water or sulphuric acid—debris of plants, infusoria, insects, and even small crustacea. Dr. Balestra has described spores and sporangia of a little algoid plant in the air of the Pontine Marshes. Lemaire and Gratiolet, in 1864, found in the air of one of the most unhealthy marshes of Sologne spherical, ovoid, and fusi- | form spores and a large number of pale cells, products, no doubt, of vegetable putrefaction. It has been supposed, by Schonbein and others, that ozone is deficient in marsh- air; that the quantity of ozone in the atmosphere and the prevalence of malarial diseases have an inverse propor- tion; and that ozone, by virtue of its supposed power of destroying organic matters in the air, is an antidote to miasm. There is, however, no evidence at all that ozone and malaria are antagonistic, or bear to each other any relation whatever. These various examinations, though interesting, bring us no nearer to a solution of the ques- tion, What is the nature of malaria 2 All of the many substances and forms thus far observed in malarial local- ities may be found equally in districts perfectly salubrious. That it gains access to the system principally through the respiratory organs is quite certain. What we really do know of it has reference more particularly to its mode | of action. It is most dangerous when the Sun is down, and it seems almost inert during the day. It appears providential that the sanne agency which is so potent in its production should be the principle instrument of its de- struction. It loves the ground, where in many regions it 36 SELECTED. . -**- is so concentrated and deadly as to destroy the incautious sleeper on the earth almost as quickly as the most noxious gas. Hence it is generally regarded as having specific | gravity heavier than that of air, but this is by no means certain. It is doubtless rendered heavy by combining with night-fogs and dews, but upon their being dissipated by the Sun it rises into the air and probably becomes innocu- ous by wide diffusion and dilution. It is intercepted by | impediments, such as walls and groves of leavy trees, which obstruct the winds that bear it. Perhaps the latter also neutralize it by absorption. It is likewise neutralized and probably absorbed in passing over a considerable body of water—especially salt-water. The distance neces- sary to effect this result naturally varies with circum- stances—force of winds, concentration, intensity, and abundance of the poison itself. According to Blane, in the channel between Beveland and Walcheren, 3,000 feet of water rendered it inert. In china, three-quarters of a mile, and in the West Indies, one mile, have been required to be effectual, Recognizing the facts mentioned, the precautions to be observed against malaria are quite obvious. In built-up cities we are protected by pavements and sewers to a great extent, and probably also by the character of the atmos. phere, which is artificially warmed by radiation at night, and impregnated with gas which, though injurious in other ways, are antagonistic to malarial emanations. But in malarial suburban and country districts it is otherwise. There certain precautions are necessary. If possible, ele- vation of a dwelling-place, at east 500 feet above the source of the miasm, is to be recommended in temperate climates, and from 1,500 to 2,000 feet in the tropics. If this be not practicable, thorough subsoil drainage, filling up of low and moist grounds, covering the earth with closely cut herbage, belts of umbrageous trees interposed between the dwelling and the point of danger, but at a | sufficient distance to permit free ventilation, and the access SELECTED. 37 gººmsºmºsºmºsºsºms of sunlight; doors and windows opening principally away from the malarial quarter; the house, if possible, to be raised on pillars or arches a few feet above the ground, otherwise a sub-cellar thoroughly cemented—all these are measures of primary importance. The sleeping apart- ments should not be below the Second story, and should be provided with open fireplaces in which on damp or chilly nights a little fire may be kindled. Exposure to the open air after sunset, or until several hours after sunrise, should be avoided. As whatever tends to lower the vital powers predisposes the individual to malarial invasion, per- sonal hygiene is indispensable. It should of course be dictated by common sense, with the object of establishing and maintaing, in the words of the old maxim of the sani- tarian, mens sana in corpore Sano. SUMMER CoM PLAINT s of CHILDREN.—BY J. M. A. LLEN, M. D., LIBERTY, M. O. The wide range, under this heading, which authors, especially the older ones, have taken, is such that to un- dertake to go over all the ground from this standpoint, would require an immense deal of labor, and would not be acceptable in an essay before this learned body. Be- sides, all the older, and many of the recent writers on this subject, make many different diseases under the name of summer complaints of children, such as simple diarrhoea, inflammatory diarrhoea, cholera infantum, etc.; and all, too, expressing a condition dependent on the same or on sim- ilar causes, and attended with the same pathological re- sults. 38 SEI, ECTED, All admit that dentition, follicular change in the gastro intestinal canal, and high temperatures, are the three prin- cipal factors as operating causes. . . - Recent post-mortem examinations establish the fact, that in a large majority of cases, the cause of death was entero-colitis. Indeed, where the assigned cause of death is collapse or convulsions, &c., there is more or less of this condition present. Meigs and Pepper, in their valua- ble work on children's diseases, state that the yearly rate of mortality in Philadelphia from this disease is very large, and it is rare not to find entero-colitis. Smith and West, of London, record, as a result of their investigations of the cause of death of children from this disease, the same pathological condition. - It is true that a large number of cases recover, and in them there may or may not have been gastro-enteritis, and the opinion of many is based on this doubt. But the ther- mometer comes to our assistance, and in my hands has nearly universally indicated inflammation, as it has in the hands of others. I do not wish to be understood that there are no cases of this disease without inflammation, for such is not the fact. But I do think, and I believe you will bear me out in the assertion, that they are very rare, and are so mild as not to require Inedical treatment unless from reflex phenomina, If I am correct in this, that the cause of the disease, under these different headings is the same, and the pathological results the same, why should there be so many terms used to express the same thing, in substance P Does it not lead to confusion? Is it not often the case that the cause of diseases is the same but the effect different; the result of difference in the individ- uals and in the surroundings P. Yet we do not change the name of the disease, but prefix adjectives to indicate its degree. We will, therefore, regard the disease under con- sideration as gastro-intestinal irritation, with or without inflammation. The period of childhood will include den- tition. SELECTIED. 39 Doctor Jackson, in his essay of advice to young physi- cians, not inaptly regards the periods of dentition and puberty as two of the most important epochs of human existence so far as the development of disease is con- cerned. Because of the rapid changes which are going on in the structures of the body, therefore the great dan- ger of disaster, which might result from nature's being thwarted in her purposes by the many influences that sur- round each individual. In children the most prominent change is follicular in the gastro-intestinal canal, added to this is their natural excitability. IDoctor Smith, of London, in his work on the Wasting Diseases of Children, asserts that excitability in children is an indication of perfect health, and its absence denotes disease. Together we may say that they are the founda- tion of nearly all those most troublesome diseases which attend this period of life, because they are easily effected in their mutual relation by the slightest cause, and at once wholly or partially effect secretion and nutrition, produc- ing at first hyper-excitability, which may be followed by convulsibility. If this condition continues long enough to produce much waste of tissue the tendency to convulsi- bility passes off because of anaemia of the nervous cen- ters, and peripheral irritation no longer produces active congestion of the nervous centers, when we may have con- gestion from states of blood, especially of the brain, a danger much to be dreaded in the latter stage of this dis- ease, if there has been much waste of tissue. In studying the cause of the summer complaints of children we find four principal factors: Follicular change in the gastro intestinal canal, dentition, high temperature, and improper food. Strictly in the first we cannot recognize a cause, only a condition, highly susceptible and easily perverted from its natural course, owing to the active structural changes necessitating an increased supply of blood to the part, together with the excitability of the nervous system. 40 SELECTEI), Secondly, Dentition. The older writers lost sight of the first “follicular change” in the gastro-intestinal canal, and ascribed to dentition the great source of causes of the dis- eases of children. Recent authors have gone as far astray in the opposite direction, ignoring the influence of denti- tion to a great extent as a cause of the disease. In this, in my opinion, they are wrong. We will see what the facts furnish in evidence of my views on this point. If we remember the rapid structural change which is going on in the gastro-intestinal canal at this period of life, and the necessary increased vascular circulation, we can under- derstand how easy it may be changed by any influence which would effect the circulation of the blood in the part, and thereby effect secretion and nutrition. Brown- Sequard, in the tenth lecture of his work on Physiology and Pathology of the Nervous Centers, states that the supply of blood to a part may be, and often is, effected by reflex irritation, and further that nutrition and Secretion may be hindered and indeed wholly suspended from the same cause. He still further insists that this alone is suffi- cient to explain the cause of many inflammations, in Sup- port of which he gives many cases both under his own and the observation of others of equal standing. If reflex irritation is sufficient to induce the above change, we may reasonably conclude that digestion would be affected, and from this point we recognize an important factor in the production of this disease, to say nothing of the strong probability of its producing entero-colitis, which patholo- gists insist is found in a large majority of cases dying of this disease. Besides, it is within the observation of all how rapidly most of the cases improve after the tooth or, teeth have made their appearance through the gums. The patient soon regains usual strength and health, and re mains so until the approach of another tooth, Coupled with the two preceding causes we have im- proper food, alone not sufficient to produce the disease, In the majority of cases mothers have sufficient intelli- SELECT Eſ). 41 ; }.t º gence to understand how to feed children, and in the country they can always procure food of good quality. Lastly, we recognize high temperature, with its results, as the great sine gua non of crtcrual influences, and with- out this factor the disease rarely exists. As evidence, we have as many children undergoing the changes connected with dentition in the winter months as in the Summer, yet we rarely see more than the effect of reflex irritation with but little functional derangement, and very rarely struct- ural change of the alimentary canal, though we find in- creased bronchial inflammation if the child has a tendency in that direction from colds or otherwise. While we place heat as the most prominent factor, and as has been shown the disease rarely exists without it, we do not wish to be understood as considering it per se the cause, but, that it favors vegetable and animal decomposi- tion, and the rapid development of certain forms of organ- ism, which float through the atmosphere either as carriers or producers of disease, just which, science has not yet determined. - * My reasons for the opinion that heat is not a factor per se, are these: It has been abundantly proved that heat alone will not produce the bowel diseases which some- times prevail as epidemics. Hubner——Ziemssen's cyclo- poedia—states that while bowel affections are more fre- quent in tropical countries than elsewhere, yet there are many places in the tropics where these diseases are un- known, although the mean temperature and the surround- ings are the same. I have witnessed as doubtless others have, epidemics of dysentery in mid-winter. If high tem- perature alone is sufficient to cause these diseases, why do we not have them annually as epidemics, for their is no great difference in our annual temperatures. It is a fact, which we have all observed, that bowel affec- tions are much oftener prevalent, both in adults and chil- dren, in some seasons than in others, although the mean emperature is the same. Again, bowel affections, both in 42 - SEILECTED. | adults and children, seem to manifest themselves more in some localities than in others, and not in the same locality each year, although the temperature, inhabitants, soil, and its vegetable growth, and, in fact, all the surroundings, re- main the same. It is the observation of every physician that when there is an epidemic of bowel affections in adults, we find a large number of summer complaints of children less amenable to treatment than ordinarily. It seems evident that the cause of this disease, so far as high temperature is concerned, is the same as that which would produce gastro-intestinal irritation, or inflammation in the adult, plus follicular change and dentition, Again, it is sure to be more frequent and more fatal where families are crowded together in filthy houses or narrow and filthy streets of cities, and indeed just where we would expect the rapid development of the lower form of organism. While I do not consider these forms of life as primarily the cause of the disease, yet I do believe that when they are absent the disease is very mild, and only the effect produced from reflex irritation. Its range of symptoms are so wide that I shall only mention some of the more prominent. In the Inild cases there is only slight reflex irritation, producing fretfulness for a few days, with an exacerbation of fever during evenings, which lasts only a few hours, at- tended with increased circulation of blood, excitability, slight nausea, and two or three actions daily from the bowels. These symptoms pass off in a few days, if proper treatment is used. In the more severe we have the above symptoms increased in intensity, with early manifestations of entero-colitis, manifested by hot skin, rapid pulse, and with or without nausea. Bowels acting every three or four hours, and oftener if thc rectum becomes involved, which is the case frequently. During the existence of the active state there is more or less delirium, and often con- vulsions. If the mucous membrane of the stomach be- comes involved, we have nausea, which also may exist merely from reflex irritation, It is often the case the at- SELECTED, 43 tack is more insidious, the child being able to run about for several weeks (only suffering from the effect of reflex irritation) until it becomes exhausted to a degree that it has not strength enough to walk; then the waste of tissue is very evident, because of failure to digest enough food to replace the waste caused by the exhausting discharges which are increased by undigested food undergoing fer- mentation in the alimentary canal, the symptoms gradually grow worse, wintil the most extreme exhaustion is pro- | duced. - | These are often the most rebellious cases to treat, if not | taken early, and it is rarely the physician is consulted early enough to render the aid he wishes; it is my opinion that many similar cases could be rendered very mild if || properly treated at the beginning. The tongue is a very - valuable indication as to the stage, and as to the effect produced by the inflammation. In the early stage it is covered with a whitish Coat, but if the disease lasts long enough to produce ulceration of the bowels, it becomes red and pointed. The heart action, which is strong at first, becomes very feeble and rapid in the latter stage, often its beats cannot be counted, this is the cause of that very fatal condition—anaemia of the nervous centers, fol. lowed by congestion, the result of stasis of the blood. If this state of the circulation is not relieved, and the patient lasts long enough, it is apt to be followed by inflammation of the brain. - We have a condition in childhood that is in no wise different from cholera morbus in the adult, and should be so considered. It has the same train of symptoms, but it is more fatal in childhood because children have not the: strength to support the exhausting discharges, and in them is readily produced collapse. I have stated that the evidence is positive that the pa thology of the disease is gastro-intestinal inflammation, more frequently affecting the ilium, coecum, colon and rec- tum. In many of the protracted cases ulceration of the wº 44 - SELECTIED, bowels is present, and often enlargement of the mesenteric glands; in other cases the lymphatic glands become in- volved in the latter stage of the disease. In the manage- ment of this disease much depends on cleanliness and pure air. The child must be kept perfectly clean, and the discharge from the bowels removed from the house at once, as they may become foci for development of organ- isms. Pure air, night and day, is indispensable, the want of this alone is sufficient to explain the greater mortality in cities than in the country. - Where there is a predisposition to this disease, and especially if the child be feverish toward the close of the day, I have found much benefit from having the child. bathed several times during the evening, in warm weather, in water at a temperature of four or five degrees lower than the temperature of the child. The child's food should be from its mother's breast, if not contraindicated. In the absence of this our effort should be to furnish it as nearly like that in composition as possible. In the use of medicine I will mention them in the order in which I rate their value. We have shown that reflex irritation is sufficient to ar- rest secretion and nutrition, by controlling the amount of blood furnished a part, also sufficient of itself to produce inflammation. In my opinion reflex irritation is the cause, in a large majority of cases, of arrest of follicular change, thereby affecting nutrition and Secretion, and laying the foundation of the disease. If this is true the course we should pursue is plain. That is to control the reflex irri- tation. To do this we resort to those remedies that have known power in this direction. My experience has taught me that opium, in some of its forms, possesses this to a larger degree than any other remedy, when the phenom- ena are from peripheral irritation. I therefore begin the treatment with opium, and prefer either the simple tinct. or the camphorated. The amount given is just sufficient to keep the patient comfortably under its influence, repeating / SEI, ECTED. 45 the dose every three or four hours, and, as the irritability subsides, gradually lengthening the interval and lessening the quantity. I am prepared to hear you say that it would increase the tendency to convulsion where there was much febrile excitement; but such is not the result. You very much lessen this tendency by controlling its cause. In the middle stage of the disease, if there has been much waste of tissue, I give it for its tonic effect on the nervous system, and to give tonicity to the blood vessels, and thereby lessen the tendency to coma from this source, After an experience of several years in the use of opium in this condition, I have not had a single case of coma from stasis of blood in the brain. Besides, the use of opium lessens glandular irritation, and thereby lessens the tendency to the production of white corpuscles in the blood, so much to be dreaded in the latter stages. In connection with opium in the first stage, bicarb, potass, given in Carminative water, also large doses of qui- nine during the remission of fever, which occurs during the morning. If the disease is protracted, I continue the quinine in smaller doses (occasionally intermitting for a few days.) In this remedy we have a good general tonic (and par- ticularly to the heart) in addition to its recognized influ- ences in Septic diseases. Astringents I never use in the first stage, unless the ac- tions are very serious and large, but think they are of much benefit later in the disease. My preference is for plumbi acetas, or tannin, in Suitable doses. I also use in the latter stage dilute sulphuric acid with opium, and re- gard it as very valuable. Where there is much exhaus- tion, and the tongue is not red, and the stomach will bear it, I have found much benefit from Ferri et quin, cit, given in port wine. A valuable tonic may also be found, in the latter stage, in acid, hydrochlr. dil. with pot. chl. In the latter stage, where the patient is much reduced, I have found benefit from cod liver oil rubbed on the skin. Where 46 SELECTED. sºs ºssºmsº * ulcerations of the bowels are present, I find much benefit from ol. terebinth. with opium. I also have used with decided benefit, creosote in the latter stages, especially if there was ulceration present; also angenti nitras. In all stages of the disease, when you are using opium freely, it is indispensible to give a dose of castor oil every 36 or 48 hours to remove undigested food and vitiated secretion, mucus, etc., from the alimentary canal, to pre- vent their becoming a source of irritation and blood poisoning. If the rectum becomes involved much benefit may be expected by using emeulcient and astringent in- jections, and if the inflammation is great, cold water injec- tions, given frequently, are of decided benefit. In the lat- ter stage, especially if there is evidence of ulceration, I use injection of solut. arg. nit. gr. xx—xl twice daily. Alcoholic stimulants should be given as soon as there is evidence of the failing strength of the child, and used freely. I feel sure many cases are lost by neglecting to begin stimulants early enough, and to give them in large enough quantities. - Other remedies are mentioned by authors, but I consider them only adjuvant to what I have mentioned. The line of treatment indicated is consonant with my views of the disease, and has been more eminently successful than that practiced years ago, sic calomel, blisters, etc.—Medical Association of the State of Missouri, 1877. SALICINE IN THE TREATMENT of THEtſ MIATISM. Mr. A. D. L. Napier, in a short article on the action of salicine, contributed to the Practitioner (June, 1876), thus *—3*. *º-º-º: & –44–1 Aº-ºº: **-*A------ SELECTED. 47 speaks of his experience with this drug in rheumatism : The form of rheumatic disease for which I have most frequently ordered salicine is the arthritic, and in these cases relief was almost invariably experienced. In one case of severe arthritis of the left finger, wrist, and ankle- joints, decided benefit attended the exhibition of a fifteen- grain dose, and, though the disease was of six days' standing, complete relief from pain was experienced after three other doses. In such cases I have repeatedly seen reduction of pain, redness, heat, and swelling about an hour and a half after the administration of a twenty-grain dose. The salicylate of soda, in addition to its general action in lessening arterial tension, acts frequently as a powerful diaphoretic, producing increased perspiration, large flow of urine, and in some cases an increased quantity of Saliva. These latter effects seem to be more often caused by the soda salt than by the acid. Although swelling fre- quently is materially decreased in a short time by salicine, yet in some cases this is not so; I have a patient at pres- ent who suffered from rheumatic arthritis of the wrist joint, was treated by salicylate of soda, and relieved of all acute pain, more than a month ago, whose joint is still greatly swollen, and useless for all active exertion; he is now rap- idly improving under galvanism. Symptoms exactly similar to cinchonism may follow the prolonged use of salicine. An old gentleman, who was under my care suffering from rheumatic affection of the wrist and ankle joints, was ordered twenty grains of sali- cylate of soda every two or three hours; a few doses speedily cured him. He ceased taking the drug, and was again similarly affected, about ten days after his first at- tack; the drug was resumed, and he was recommended to continue it for a fortnight, in ten-grain doses twice daily, after all symptoms had disappeared. He only used it, however, for two or three days. Within a short time he again became ill, and having experienced the decidedly \ R- –A– 48 - RECORDS. beneficial action of his former medicine, resumed taking it without sending for medical advice. On this occasion, evidently desiring to make assurance doubly sure, he per- severed in taking twenty grains every three hours for more than a week, although the pain had almost ceased after two or three doses. IHe then became very deaf, had ring- ing noises in the ears, experienced severe headache, thirst, loss of appetite, and felt dull and heavy. The medicine was discontinued, and the unpleasant symptoms shortly vanished. It is necessary for the perfect action of salicine that the drug should be used in reduced doses for some time after acute symptoms are dispelled; I have often seen a relapse from a too early cessation of the medicine. In muscular rheumatism, salicine affords some relief, but its action in such cases has given uncertain results in my hands. In neuralgic affections, I have seen good from salicylic acid, more especially in mixed cases of neuralgia and rheumatism ; one case of neuralgia of the brachial plexus was undoubtedly cured in a very short time. From its greater solubility, and from its being more easily taken by the majority of patients, I have found Salicylate of soda preferable to the salicylic acid. With the exception of the greater diaphoretic action of the former, I have been unable to discriminute between their therapeutic action. REcoRDs of THE LINToN DISTRICT MEDICAL SocIETY. MonTGOMERY CITY, Mo., April 4, 1877. The sixth annual session of the Linton IDistrict Medical Society convened in the Masonic Hall in Montgomery | JR ECO RI) S. 49 City, Mo., on Wednesday, April 4, 1877, at 3 p.m. The house was called to order by the President, Dr. W. T. Lenoir, of Columbia, Mo., and exercises opened with prayer by the Rev. Dr. Vincil, of Mexico, Mo. The President then congratulated the Scoiety on its past success and its ſuture prospects, after which Dr. H. W. Pocoke, of Montgomery City, in a brief speech, welcomed the members of the Linton District Medical Society to that city, and tendered them the hospitalities of its citi- Zen S. On motion of Dr. Rothwell, members of the press were invited to attend during the meeting. The minutes of last meeting were then read and adopted. The roll was called, and the following gentle- men answered to their names: Drs. W. Dickinson, St. Louis; A. S. Loving, Wright City; M. T. Warren, Middleton ; — — Goodrich, Wentzville ; M. Yates, Fulton ; S. J. Burch, Warrenton ; A. W. Graham, Warren county; W. B. Adams, Dan- ville; J. F. Hanna, Ashley; S. Overall, C. M. Johnson and J. R. Mudd, St. Charles ; G. W. Broome, Moberly ; C. G. Hubbell, Rocheport; J. I. Bodine, H. W. Pocoke and — Caldwell, Montgomery City; W. F. Hum- phreys, Concord ; J. M. Foreman and E. A. Ball, Jonesburg; S. N. ltus- sell, P. French, W. Humphrey, W. W. Macfarlane amd J. P. Rothwell, Mexico; W. T. Lenoir, A. W. McAlester, J. N. Garnett and J. H. Dun- can, Columbia. On motion of Dr. Broome, the President filled facancies on standing committees as follows: (1.) On Scientific Communications—Drs. Overall, Humphreys and IIulyl)ell. (2.) On Credentials—Drs. Mudd, Pocoke and Macfarlane. (3.) On Medical Ethics—Drs. McAlester, Broome and Rothwell. (4.) On Medical Eulucation—Drs. Humphrey, Foreman and Broome. The committee on credentials presented the names of the following gentlemen for membership, who were unani- mously elected : Dr. Martin Yates, Fulton. l)r. S. J. Burch, Warrenton. Dr. A. W. Graham, Hopwell Academy, Dr. McAlester, chairman of committee on medical eth- ics, Dr. Pocoke, on arrangements, and Dr. Duncan, on publications, made their reports, which were accepted and committees discharged. The committee on scientific com- 50 REcoRDs. munications reported only one paper presented to them. The committee on medical education then made the following report: “That in surveying the field of medical education, one of the most pleasing features. that presents itself is the high standard our own University is taking in the standing required of her graduates. Abandoning the idea entirely that a certain length of time with the pay- ment of the requisite fees entitle the student to his diplo- ma, graduation now depends upon the evidence given not only of proficiency but also of high attainments, as evinced by a class standing and Standing on examination, even higher than that required by the University of Virginia, which has gained for itself a deservedly high reputation, not only at home but in Europe. This fact is highly grat- ifying, and we hope to see our University in this respect and all others primus inter pares.” This report was unanimously adopted. The Treasurer made his report, showing collected dur- ing past year, $64.00; paid out, $72. I4; leaving $8. I4 still due. The Treasurer, however, reports that the yearly dues to be collected at present meeting will liquidate the debt and leave in treasury at least $2O.OO. The report was received, On motion of Dr. Overall, the Secretary was instructed to write to Dr. Pitman in regard to funds in treasury at the time that gentleman vacated the office. The election of officers for the ensuing year was next in order. The following was the result: President—Dr. W. B. Adams, Danville. 1st Vice-President—Dr. W. F. Humphrey, Concord. 2d Vice-President—Dr. J. R. Bodine, Montgomery City. Treasurer—Dr. S. N. Russell, Mexico. Recorder—Dr. W. W. Macfarlane, Mexico. Secretary–Dr. J. H. Duncan, Columbia. On motion of Dr. Rothwelſ, the reports of special com- mittees were heard. º Under this head Drs. W. W. Macfarlane and J. R. Mudd read very elaborate and excellent reports on Topography of Audrain and St. Charles counties. The gentlemen ap- RECO 13 DS. 51 pointed on the Topography of the other counties either being absent or having only verbal reports, were, on motion of Dr. Macfarlane, continued to the next meeting and in- structed to have written reports, and they be placed in the hands of the publication committee. The society then adjourned to meet at 7% p.m., April 4, 1877. Society met at the appointed hour, Dr. Lenoir, Presi- dent in the chair. - Dr. Russell, of Mexico, Mo., chairman of a committee appointed by the president at the last meeting to consider the feasibility and practicability of publishing a Medical Journal in connection with the Society, announced his readiness to report. The report was made, and, after a long discussion in regard to publishing the Journal, Dr. Macfarlane moved to defer the further consideration of the matter until to-morrow morning, and Dr. Duncan be added to the committee. Carried. The reading and discussion of papers now being in order, the Secretary read a communication from Dr. Jack- man, of Rocheport, Mo., on the “Therapeutic Properties of Ammonium Carbonate.” The essay showed research and study on the part of the author and elicited the com- mendations of all present. The value of this agent in | pneumonitis was urged, and in all diseases in which there is an excess of fibrine. Its modus operandi in the treat- ment of these diseases is its property of maintaining the fluidity of the blocq. The paper was discussed by Drs. Adams, Rothwell, Humphreys and Garnett. The next subject for discussion was “Hysteria.” Dr. A. P. Spence, the gentleman appointed to open this dis- cussion, being absent, the Society devoted one hour to its consideration, Dr. Macfarlane thought it common to both sexes and all ages; that it is a nervous disease due to physical disorders, and that every case of Hysteria is a case of insanity. The last view, expressed by the Doctor brought forth a discussion of some length, participated in - 1– 52 JR ECO RIDS, * by Drs. Rothwell, Adams, Humphreys, Pocoke, Foreman and Russell. On motion of Dr. Garnett, Society adjourned to meet at 8 a. m., April 5, 1877. Society met at appointed hour, President in the chair, Dr. Russell, chairman of committee on Medical Journal, made the following report, which was accepted : GENTLEMEN:—In addition to former report, we submit that, as it is the expressed wish of the Society to establish a Medical Journal, and as it is the opinion of some that the funds for printing the same should be first secured by advanced payments from subscribers, thereby neeessitating much delay and the use of some money for other publica- tions, circulars, etc., and as such a plan would embarrass those having it in charge—in asking payment for a Jour- nal not yet in existence—we are inclined to discourage this plan and recommend the following: The cost of printing two issues of the proposed work, as ascertained will be $85.00. After paying present indebtedness of the Society $30.OO will remain in the hands of the Treasurer, leaving $50.OO or $55.CO to be obtained. Could 30 names be secured who would pay as soon as the work was done or in advance, the required amount would be raised and the enterprise could be inaugurated, with the exception of the editor's pay. To provide for that we have the certain prospect of, we think, $50.OO now in the hands of the former Treasurer, with the fair prospect of at least 50 addi- tional subscribers, amounting to a very probable $150.OO as editor's pay. We recommend: First, That an imme- | diate call be made for 25 guaranteed subscribers. Second, That two editors be now appointed to take charge of the work, under such instructions and limitations as the Soci- ety may direct. Respectfully submitted. S. N. RUSSELL. t W. F. HUMPHREYs. It was then moved by Dr. McAlester that this Society have a Medical Journal to be published semi-annually, and RECORDS. 53. * gººmsº that a committee of three be appointed by the President to retire and select two editors for this Journal and report immediately. Adopted. The following committee was appointed: Drs. Fore- man, Rothwell and Mudd, to which was added the Rev. Dr. Vincil. The committee retired and after a few mo- ments returned and presented to the Society the names of Dr. S. N. Russell, of Mexico, and Dr. J. H. Duncan, of Columbia, as editors of the Journal, who were unani- mously elected. On motion of Dr. Rothwell, it was de- cided to issue the Journal under the title of “The Linton District Medical Journal.” A motion was made and carried that members who have heretofore read communications be requested to send them to the editors. On motion of Dr. Russell, a recess of ten minutes was taken. Society met, Dr. Lenoir, President, in thc chair. The gentleman appointed at last meeting to read an essay upon “Epilepsy” being absent, the subject was taken up and discussed by the Society. Dr. Foreman thought it due to a molecular change in the nervous matter, and that there is a retrograde process in the nerve tissue going on. The blood vessels of the brain dilated and congested cause the paroxyms. The Bromides act by contracting the vessels. The subject was discussed by Drs. Humphreys, Macfar- | lane and Hanna. The treatment in such cases is Bromides and Valerian ; Oxide of Zinc is sometimes beneficial. The next subject for discussion was “Leucocythemia,” to be opened by LJr. Pearson, of Louisiana, Mo, He was | absent, and Dr. Macfarlane, of Mexico, made a few re- marks upon it, after which the Society took up the dis- cussion of “Puerperal Fever.” The discussion was opened by JDr. McAlester, of Columbia, who advocated the view that there is a fever occurring during the Puerperal state which can only be called Puerperal Fever. The Doctor 54 RECORDs. :-º-º: **-*. - ºf ably advocated his view, presenting it in the strongest possible manner. - Dr. Garnett, of Columbia, read a very ably written ar- ticle upon the subject opposing the views of the above gentleman. Dr. Rothwell, of Mexico, advocated the views of and agreed with the first gentleman. - - On motion of Dr. Russell, the further discussion of the paper was postponed until 2 p. m. - . . . Society then adjourned to meet at 2 p.m., April 5, 1877. Society me at the appointed hour, Dr. Lenoir, Presi- dent, in the chair. . The discussion of Puerperal being resumed, Dr. J. H. Duncan, of Columbia, made a few remarks, advocating the view of the relationship between Puerperal Fever, so- called, and Puerperal Septicaemia and Pyaamia. He re- garded it as a septic disease, not distinct from other fevers occurring during Puerperal state ; in fact, the name was a misnomer. - Dr. Loving, of Wright City, considered it a septic dis- ease, and not a specific fever, and clearly showed the rela- tion between Erysipelas and Puerperal Fever, so-called. The next subject for discussion was “Breech Presenta- tions,” which was opened by Dr. Garnett in an excellent speech pointing out the danger in such cases and advocat- ing the use of Traction, after the manner of Dr. Penrose. The Doctor dwelt specially upon the fact that most chil- dren may be saved if the requisite amount of force is used in traction, to take the place of the propelling power of the womb which is now lost to the child; also the im- portance of bringing the face under the Pubic Arch in- stead of in the hollow of the Sacrum; in this position not only is traction more easily made, but death from suction of liquid in the air passages is prevented. The subject was discussed by several gentlemen, all of whom were pleased with the views of Dr. Garnett. Dr. French made a few remarks upon “Cholera In- w-r- Records. 55 fantum,” showing its dangers, treatment, &c. He gave Calomel, good food and fresh air. * Dr. Humphrey, of Mexico, thought it a frightful dis- ease from the beginning, eliminating from the blood large quantities of Serum, and occurring oftener in hot weather. Diaphoretics should be used and purge the skin and thus carry off a great deal of poisonous matter; during the evacuating stage control the bowels with opium. Use stimulants in stage of collapse ; give cold water. The subject was also discussed by Drs. Loving, Mac- farlane and Garnett. Dr. McAlester then spoke upon “Hemorrhoids,” giving the Patholgy, Etiology and Treatment of External and Internal piles. He used. Carbolic Acid to deaden thc sen- sibility of the Tumor, and if it is external simply cut it open; if internal, either ligate, transfix or clamp. He al- ways tried local applications first. • Dr. Duncan agreed as to the treatment of Piles; had never used the clamp but treated by local applications and ligature. On motion of Dr. Russell, there was a recess of ten minutes. Society met, Dr. Lenoir, President, in the chair. Dr. McAlester read the following biographical sketch of the late Dr. Chandler, which was received, ordered spread upon the record and a copy sent to his family: “Dr. C. Q. Chandler was born in Louisa county, Va., January 26, 1826. His father moved to Cooper county, Mo., in 1836. He went back to Virginia at the age of 14 to finish his education, and study his profession under his uncle, Dr. Charles Quarles. He attended his first course of lectures in Richmond, Va., in 1846-7 at Hampden- Sidney College. He graduated at the University of Penn- sylvania April 8, 1848. He was 22 years old when he graduated. His preceptor thought he was too young to begin practice by himself (successfully) and urged him to remain in Virginia and practice with him a year, which he *— 56 - IRIECORDS. did. He returned to Missouri in 1849 and practiced at Conner's Mill, Cooper county, until August, 1853, when he removed to Rocheport, where he continued the practice for 22 years. He died of rheumatism of the heart, Feb- ruary 2, 1875. What more can be said of him than as a man, a citizen and as a physician he was faithfully tried and found to be true. He left us with a full assurance of a happy hereafter.” Dr. W. Dickinson, of St. Louis, presented to the Society a communication upon “Lesion of the 3rd Pair of Cranial Nerves.” He presented a case illustrating his subject showing the causes, effects and treatment of paralysis of || this nerve. He gave origin, distribution and function of the nerve. He also showed that when both eyes are effected the lesion is at the base of the brain. The prog- nosis depends upon the cause. If the cause is reflex, rheumatic or syphilitic and of short duration it is favorable. Best treated by continued galvanic current for 9% to I min- ute at a sitting; also Iodide of Potassium, Protiodide of Mercury and Cathartics. The paper was one of great merit and the Society presented their thanks to the gentleman for this voluntary Scientific communication. On motion of Dr. Russell, Mexico, Mo., was selected as the next place of meeting. The society then adjourned to meet at the college chapel at 7% p.m., April 5, 1877. Society met at the appointed hour, Dr. Lenoir, Presi- dent, in the chair. - Under motions and resolutions, Dr. Humphreys offered the following amendment to Section 5, Article I, of By- Laws: Insert after “annual meeting,” in parenthesis (“or during the following year,”), the section will then read as follows: “Any Physician, after having been admitted as a member of this Society, shall retain his membership by the pay- ment of an annual fee of $2.OO at each annual meeting (or during the following year) as long as he is in good stand- RECORDS. - 57 ing in his profession.” This was adopted. Dr. Rothwell, of Mexico, offered the following resolu- tion, which was adopted : Jºesolved, That a vote of thanks lyc tendered the ploysicians and citi- zens of Montgomery City for their courtesy and hospitality to the mem- bers of this Society during their present meeting. The President then appointed Drs. Garnett and Hanna to conduct the newly elected President, Dr. W. B. Adams, of Danville, to the chair. The President elect thanked the Society for the honor conferred, after which the retiring President, Dr. W. T. Lenoir, of Columbia, delivered the annual address; sub- ject, “Professional Jealousy,” - On motion of Dr. Garnett, delegates were appointed to the meeting of the State Mcdical Society, which convenes in Kansas City, April I7, 1877. The President appointed the following: Dr. W. H. Lee, Audrain county; Dr. A. W. McAlester, Boone; Dr. W. S. Hutt, Lincoln; Dr. Jno. S. Pearson, Pike; Dr. H. H. Middelkamp, Warren ; Dr. J. R. Mudd, St. Charles; Dr. E. M. Kerr, Callaway; Dr. G. W. Broome, Randolph ; Dr. M. Y. Warren, Mlontgomery. Un motion, the President, Dr. Adams, of Danville, and Secretary, Dr. Duncan, of Columbia, were also appointed delegates; Also Dr. T. Allen Arnold, of Columbia. On motion, the President appointed the following dele- gates to the National Society which meets in Chicago, Ill., in May, 1877: Dr. W. Humphrey, of Mexico, and Dr. J. M. Foreman, of Jonesburg. The following standing committees for the ensuing year were appointed: (1.) On Scientific Communications—Drs. Humphreys, Lee and Fore- Il) &lll . (2.) On Credentials—Drs. Loving, Rothwell and Lenoir. (3.) On Medical Ethics—Drs. Hanna, Mudd and Maupin. (4.) On Publications—Drs. Garnett, Macfarlane and Middelkamp. (5.) On Medical Education—Drs. French, Broome and Bodine. (6.) On Arrangements—Drs. It oth well, Humphrey and Russell. The following gentlemen were appointed to read essays at the next meeting of the Society, in November, 1877, upon subjects opposite their names: (1.) Dysentery–Dr. Samuel Overall, St. Charkes, 58 - R. ECO RIDS, * (2.) Modus Operandi of Chloroform— Dr. P. French, Mexico. (8.) Skin Grafting in Syphilitic Ulcers—Dr. A. S. Loving, Wright City. - (4.) Treatment of Urethral Stricture—Dr. T. Allen Arnold, Colum- bia. - - (5.) New Remedies—Dr. J. A. Mathews, Ashley. (6.) Electricity—Dr. H. H. Middelkamp, Warrenton. (7.) Diphtheria—Dr. W. F. Humphreys, Copcord. (8.) Fractures and Dislocations in and near the Ankle Joint—Dr. W. W. Moss, Columbia. (9.) Menopause—Dr. J. N. Garnett, Columbia. g (10.) Treatment of Fractures of the Femur—Dr. J. N. Foreman, Jonesburg. Dr. Humphreys, of Concord, presented the Society the picture of a child born, at term dead, with no development of hips; umbilicus too far to the right side, but all parts from there upward natural. Instead of two legs they fused into one, so as to form something resembling the tail of a fish, There were no openings for the discharge of feces and urine. - - On motion of Dr. Garnett, Dr. Humphreys was in- structed to obtain a wood cut of this monster and prepare an article concerning it, for publication in the Linton Dis- trict Medical Journal. - Dr. Hubbell, of Rocheport, reported a case of a growth of hair, eight inches long, from anterior wall of Rectum, The Doctor removed it, cauterized the part with Chromic Acid, and thus far there is no return of it. Dr. Macfarlane, of Mexico, was called to a lady in con- finement; child born with a Tumor extending from the centre of the Sternum under the arm and to the spinal column. The Tumor was eight inches long and four inches wide. On it were cicatricis. It was movable. Child now doing well. He thinks it a Twin Pregnancy. On motion of Dr. S. N. Russell, Society adjourned to meet in Mexico on Tuesday, the 6th day of November, I877, at 3 o'clock, p. m. - - W. B. ADAMS, M. D., President, J. H. DUNCAN, M. D., Secretary, JDanville, Mo. & Columbia, Mo. ANNU A L A D D]3. ESS. 59 º|: ANNUA I, ADDRESS OF THE IR&T'ſ RING PR EsłD ENT, W. T LENo1 R, M. D., CoLUMBIA, Mo. Gentlemen of the Linton District Medical Society: It is the imperative duty of every true Physician to labor earnestly and persistingly to promote the interests and honor, and to defend the good name and integrity of our noble Profession. We can draw sweet consolation and, in the fact, see an earnest of better things, that in all the reputable Medical Schools the standard of scholarship has been raised, and with almost universal disposition and practice to still demand higher and increasing proficiency and capabilities in the aspirants for such distinguished honor. This is right, and we most truly and sincerely indorse it. Then, too, we aren ourished and strengthened through the benign and up-building influence and potency of County, District, State and National Medical Associa- tions, besides a brilliant host of active, earnest co-laborers all over the country, aggregating a stupendous and invin- cible army which is achieving glorious victories for Sci- ence, and dispelling the superstitions and crudities of less enlightened ages, throwing a halo of brightness on the present, and justifying larger hopes for the near future. While all this is true, let us not be deceived, for we should know and can only possibly fail to recognize the fact that there are instrumentalities at work—materies 1/zor- ôi–which have touched corruptably our ranks, whose legimate and necessary tendency and effect are to enervate and destroy our capabilities for good and to bring reproach on the name, Doctor. I have not the leisure or disposition at present to discuss all these dishonoring and destructive evils, for it would unduly extend this paper. I will direct, then, your earnest attention to one of the most despicable and potent: PROFESSIONAL JEALOUSY. There is a peculiar attribute belonging to many words in the English language, by virtue of which they possess a weight and significance of meaning that can not be - - - ** - - - - *** *...* . . ." - - º :* - (50 ANNUAL ADDRESS. expressed in terms. This attribute is understood and felt by some innate power of intellect, which itself can not be fully described. When we undertake to define such words we generalize. Thus, who can define the word conscience so as to convey to the mind of him who has not learned its meaning, all that we recognize and feel the thing to be?" In such cases, the word furnishes a sort of point-d'appui for reflection and investigation, How complicated and labyrinthian are the difficulties suggested when we introduce a modifying term, or under- take to specifically circumscribe and apply a given word 1. Now there is not a hidden, but an indefinable meaning in the word jealousy; and when we limit it in the combina- tion “Professional Jealousy,” the very restriction intensifies its meaning, so that we no longer can depict the hideousness of our conception of the enormity, nor artist's brush por- tray to the eye outlines of a deformity so disgusting. A concentration of the meaning of all its synonyms, a com- bination of all the figures that have been used to illustrate it, still leaves something which we appreciate, but can not embody in a definition. Of all the definitions given of jealously, we select that one of Webster which describes it as a “painful appre- hension of rivalship in cases nearly affecting one's happi- ness,” as the one which, itself amplified, most nearly con- veys our idea of the passion—aye, passion ; for it is a suf- fering, a disease of mind which, among the possibilities at least, can induce a faulty physiological action—disease of mind which is contageous to the moral faculties; disease which corrupts; disease which enervates intellectual and moral forces, perverts legitimate instrumentalities of men- tal growth, and destroys the nobler impulses of the human heart. As there is no class of society to which the finer ele- ments of a noble manhood are more essential to the conn- plete success of its profession than practitioners of medi- cine, so to none is jealousy such a hinderance and curse. ANNUAL AIDDRESS. - 61 i. - xx - ſt *4. I hold it to be a truth, universal and incontrovertable, that no man who is constitutionally of a jealous habit, nor one who has perverted the natural bent of an otherwise amia- ble disposition into this channel, can do his duty as a physician, nor develope the full measure of his capabilities and powers of usefulness. Such a disposition is not only an evil in a community, but is debasing to its possessor, a reproach to the profession, and an incubus which impedes its progress to a place in the esteem and veneration of cul- tivated and enlightened society—a place to which it is en- titled and should assume and hold. If these are truths, our profession owes it to its own dignity, to its own self- respect, and to its own highest aims to correct this, a wide-spread evil, in its ranks. We must find an antidote for this virulent poison. But, is our position on this question an extreme one P Is the view exaggerated, or the picture over-drawn P Let uS SCe, The science of medicine is not only a growth and a de- velopment, but it is at present, and always will be, a pro- gressing development. It is a well understood and univer- sally acknowledged fact, even whether true or false, that the types of diseases are constantly changing, or new dis- eases are brought to light, or developed, yet the physi- cian must keep himself thoroughly posted in the written and unwritten experience of the profession. He mnst ap- ply all the energies of his mind to the theories advanced by and to an analysis of the real or reputed discoveries and experiences of his brethren, or he falls behind and is overtaken by the credulity and crudities of quacks and absurd old grannies. No man who neglects to study, who fails to investigate, can make a first-class physician. But the jealous man, puffed up in his own vain conceit, com- pletely reversing the order of the golden maxim “search others for their virtues, thyself for thy vices,” contemptu- ously rejects everything that his supposed rival happens first to discover. Thus, grand truths which are potent to 62. A NN U AI, A DI) RESS. -*--ºs- relieve pain and banish disease, are frequently rejected, and error is nursed. The true man—and a good physician is necessarily a true man—has a mind for impressions, and not a will to mould principles and prune truths to suit his own changeful convenience. - - It is a moral impossibility for the natural talents or ac- quired ability of the jealous physician to have full play or free growth. He becomes cynical, skeptical and obstinate. He is ill at ease with his brethren, and broods over the pro- || geny of his own self-communings. Thus, he is unfitted to understand the grandest truths of nature, or to grapple with the difficulties he is called to remove. He is con- stantly perverting nature, and fretting himself into ill hu- mor. One of earth's true nobility—whose massive genius and facile pen have depicted the Secret springs and revealed the inmost recesses and mysterious impulses of human na- ture as no one else has ever done, declares, that no man can do anything to advantage in a life of constant turmoil, disappointment and worry. But the physician, to be suc- cessful and to protect himself against the possibility of vio- lating his sacred trust, must be always at himself and have under control all the powers of mind and heart with which nature has endowed him. - It is a self-evident truth, that no man should possess the virtues of patience, forbearance, gentleness, generosity and self-denial to a greater degree than the physician. They are a part of his profession. It is his highest duty to exer- cise them without stint. But they cannot grow in the same soil at the same time with the vicious exotic-jealousy. How can a man be tolerant of the whims of a petulent invalid, who cannot brook the independent course of his brother physician P. How can he maintain courage under inevitable failure, when another's greater professional or business success, and consequently his own comparative failure, destroys his temper and his peace P - . . In a thousand ways jealousy hurls its poisoned arrows at a struggling, rising and worthy opponent. By a con- --—-a--- —x------------it-- * - - A NNUAL ADD HESS. 63 temptuous curl of the lip—by inuendo, by flat-footed lying, by misrepresentation, by sneering at glorious triumphs and brilliant successes, and by a cherished and successful plan, failing to defend and exonerate a brother from unjust and baseless accusations prefered by wickedness or malice. With the uninitiated and vulgar, which compose the larger class of mankind, such cowardly efforts degrade the profes- sion; but with the gifted few, who can disrobe the monster of his vestment of blackness and slime, and read his real status and motives, such blows demolish nothing, but Scoop-out a niche in the temple of Fame for the sure preservation of the Faithful. Whoever then wages or sympathizes with such a fratri- cidal warfare, whether he be the ambitious Tyro, just en- tering the vestibule of the rich store-house of medical truth and honor, or the hoary-headed hypocritical worshipper who has long lingered and desecrated the sanctuary by his ministrations, let him be ejected beyond the pale of recog- nition, let him be kicked without the camp, and baptized seventy times seven in the righteous, indignant frowns of an insulted and injured Brotherhood. Ours is a Profession which demands the noblest minds, the noblest hearts and the noblest lives. Let us, then, dis- countenance every tendency to narrowness, bigotry and Selfishness on all occasions, and thus elevate the standard of Professional honor by improving ourselves, correcting this grievous and wide spread evil in others, and contribu- ting directly, through a broader and more liberal spirit, to the welfare of those who entrust so much to our judgment and skill. THE LINTON DISTRICT MEDICAL JOURNAL. * COLUMBIA, MISSOURI, 1877, A NTRODUCTORY To the Patrons of the journal.- GENTLEMEN:—In offering to you, this our first issue of the Linton District Medical Journal, we are sensible to some extent, of the responsibility we have assumed, as well as of our inability to meet the demands and expectations of the Society whose organ we are to control. Yet relying upon your assurance of confidence in plac- ing us in this untried position, with the promise of patience and forbearance with our shortcomings, until experience shall have made us more competent, we venture to present you with this, though very imperfect, as the best we could do. As to the taste or style manifested in the mechanical execution of the book we anticipate entire Satisfaction ; as good at least, as the price paid should lead us to expect. In regard to the subject matter presented, while controlled by our discretion, it is by agreement, to a large extent, yours, not ours. The respective merits of which your judgment will determine, while you will appreciate its scientific worth. The plan of arrangement of the volume is no doubt open to objections, it being entirely our own. But where perspicuity and convenience are attempted, rather than established form, we ask that your criticism be lenient, promising improvement in the future, where faults 21°C Sée Il. A peculiar circumstance connected with this undertaking which gives to it a novelty almost without a parallel in journalism is, that it is not an individual or private enter- | F. DITOIR. I. A ſ,. 65 ===ºsºsº assºssmsºs prise. While to us is assigned the editorial duties of the work, they are to be performed without pecuniary remuneration, and this is here mentioned, only for the purpose of illustra- ting the relation of individual mennbers of the Society to the Journal, and their duties growing out of that relation. This is the journal of the medical men of this district, es- tablished, and to be sustained (if sustained) by them alone, Consequently, they are to be responsible for its character, including its editorial management. Therefore if the papers presented at our semi-annual meetings and the discussions thereon shall furnish records of scientific worth, then that department of our Journal will be valuable to that extent. To do which, members appointed to prepare such papers must not shrink from the duty they assume. And in the character of their productions they must endeavor to do justice to themselves—to the Society their ar- ticles represent——and worthy the perusal of the Profession at large. Again this Journal, depending as it does, upon the voluntary contributions of district members, will be lean or robust just as the pabulum is furnished from which its strength and vigor are to be derived. The success then of our Journal depending on individual members, to so large an extent, each should understand and respond to his individual duty. Not only to contribute to its pages occa- sionally, to the best of his ability, but also to furnish for publication all peculiar and anomalous cases, results in the use of new remedies, any new departure in medical or Surgical practice; thereby contributing his mite for the ag- gregate progress to which we aim. Thus, this Jour- nal may become not only the exponent of the medical abil- ity of the Linton District, but also the repository of the best experience of the day of its existence. The main object in establishing and maintaining a med- ical journal in connection with this Society is the same as thc objects of the Society itself. Those objects being “To constitute a representative body of the regular Medical Profession of the District which may advance the interests 66 ED ITO RIA II. and encourage the unity and harmonious action of the en- tire Profession throughout the District; to suppress empir- icism as much as possible ; to restrict the practice of medi- cine to regularly qualified graduates; to develop talent, stimulate medical inventions and discovery, and to main- tain our rights and immunities as medical men.” The Journal then becomes the auxiliary to the objects of our organization. We seek by organized action to accomplish for the profession what cannot be done by isolated indi- vidual effort. The above being the conditions—the resources, and the objects of our Journal, we shall expect and welcome com- munications in harmony with the same, while all matters foreign to these objects will be excluded. The principles of the practice of medicine are every- where the same. Our field, embracing nine counties, is a || fair representation of the diseases of the west, wherein is contained, we honestly believe, a Medical Profession of average learning, ability and skill. We thus possess all the elements of Professional progress and success. It is with us then as a Profession, whether we plod along the awk- ward imitators of the more skilled, or availing ourselves of the advantages we possess we shall stand abreast with those the most advanced. The age demands this at our hands. We must be more than our pioneer predecessors. And as the Linton District Medical Society was the first district organization in the State, and its Journal the first enterprise of the kind under the auspices of a district society, let the unswerving pur- | pose of our membership be to make our Society first in character and our Journal first in literary worth. The Linton District Medical Society meets in Mexico, Mo., on Tuesday, November 6, 1877, at 3 p.m. | i EDITOR.I.A.L. 67 | i We cannot refrain from calling the attention of the members of this Society to the importance of preparation for our November meeting. Remember, brethren, it is your duty to attend. Let no trivial excuse prevent your at- tendance. The success of the Society depends upon you as an individual as much as upon any other. You need the relaxation. The meeting needs your presence. Come and let us make our next session the largest, most inter- esting and profitable of any preceding one. Your duty is not only to attend, but come prepared to work. Let com- mittees, both standing and special, be ready with their re- ports; and especially would we urge those appointed to read papers on assigned subjects to respond. Nothing so mars the interest and distracts the order of business as those failures in the programme of work. Also come prepared to discuss the subjects presented. Progress in medicine can be attained only so far as its representatives become acquainted with its facts. The idea of our organ- ization is to obtain at each meeting an exhibit of the knowledge, the experience and the opinions of the Pro- fession upon the subjects there presented ; and these opinions, as expressed in the discussion of subjects will be valuable in proportion to the thought or preparation these subjects have received at home. Gentlemen, we contemplate a profitable meeting next November. Shall we have it? EDITORIAL ABSTRACTS AND SELECTIONS. CoLD APPLICATIONS IN CROUP –W. H. Lanman, M.D., || Mount Holly Springs, Cumberland county, Penn., directs || attention to cold applications to the neck in cases of croup. He wraps a cold towel around the neck and renews as often as it gets warm. This has been his practice during the last eight years with uniform good results. He suc- ceeded in removing the false membrane with Pot. Iodide; 20 grs. Senegae Syrup, 3 dra. Aquae Distill., J3 oz. Small teaspoonful every three hours.-9 ouſ nal Med. Mat. CASTRATION FOR THE CURE OF SPERMATORRHCEA.—Dr. Spaulding has brought before the Detroit Academy of || Medicine a case in which, from a boy fourteen years old, he removed both.testicles. The boy was rapidly becoming an imbecile from masturbation. Before resorting to so desperate a measure, Dr. S. consulted with several eminent medical men who deemed the operation justifiable. The result is satisfactory; the youth is acquiring good business habits.--The Doctor. FIVE CHILDREN AT A BIRTH.-James F. Pierce, of Mars || Bluff, S. C., reports a case of a negro woman giving birth on the I Ith of last September to five children. The labor was premature by one and a half months. The children were small but perfectly developed, ten and three-quarter inches long. The estimated weight of each was two and a half pounds. One female was attached to a seperate placenta. One female and three male children attached by seperate cords to the same placenta. Mother did well. Four of the children died immediately; one lived several hours.-Med. News and Ziórary, Wov. 1876, and Pacif. Med. & Surg. journal, Dec. 1876, and The Cincinnati Lancet & Observer, March, 1877. EDITORIAL AIBSTRACTS. 69 OvARIOTOMY IN AN OLD WOMAN.—Dr. C. Richards, of Joliet, Ill., operated for ovarion tumor in April, 1876, upon a woman sixty-five years old, resulting in complete re- covery.—Chicago Medical %urnal & Examiner, Sept. 1876. DR. H. HARTSHORNE'S CHOLERA REMEDY :— Chloroformi, Tinct. Opii, Spirit Camphorae, Ammoniae Aromatic, each 1} fluid drs. . Creasoti, 8 drops. Olei Cinnamomi, 8 drops, Spiriit Vini Gallici, 2 drs. Mix. Dilute a teaspoonful with a wine-glass of water and give two teaspoonsful every five minutes, followed by a lump of ice.—New Remedies. DEATH FROM NITROUS Ox1DE.—The late case in which a surgeon perished under the influence of the gas has been discussed at the Odontological Society and elsewhere. The dentist is exonerated by the fact that the deceased, a qualified. Surgeon, insisted on taking the gas and Adirecting it to be given till he had “a good snore.” It is idle to de- ny that the gas was the cause of death, and the case should be a warning as to the danger attending all anaes- thetics, journal Mat. Med., June 2 I. ExcESSIVE SWEATING.—Anhydrotics.--Anhydrotics are remedies which are of use in checking excessive sweating from disease. The sweats of phthisis especially call for these remedies. Phosphoric acid, Sulphate of copper, tan- nic and gallic acids are of some use as anhydrotics. The most potent of all anhydrotics, in my experience, is un- questionably belladonna. We are indebted to Dr. Sydney Ringer for our knowledge of this property of belladonna; and the debt we owe to him can only be sufficiently esti- mated by those who have an extensive experience of phth- isis, and who give the drug a fair trial. I have no hesi- tancy in Saying that the use of this agent completely changes the aspect of many cases of pulmonary phthisis. For the arrest of the exhausting night-perspirations of phthisis, belladonna is as potent as digitalis is in giving tone to a feeble heart. It is quite true that neither is very 70 EDITORIAL ABSTRACTS. effective in the last and final stages of disease, for indeed nothing is very potent then ; but in the early stages the ac- tion of each is very pronounced. In the night-sweats of spreading caseous pneumonia, the administration of bella- donna is followed in almost all cases by a decided arrest of the flux; and in many cases the arrest of this flux is ac- companied be immediate improvement. To produce these effects it is necessary, however, to use larger doses than those spoken of by Dr. Ringer. He speaks of from I-2OOth to I-IOOth of a grain of atropine given hypoder- mically; but as to the dose given by the mouth, I us- ually commence with I-75th of a grain, and up to I-25th; the latter dose rarely failing.—%. Milner, Fothergill. PAIN.—Outward Application of Hydrate of Chloral,—Hy- drate of chloral is capable of cutaneous absorption, and acts in this way as a local anaesthetic. I have tried it with great success in neuralgic pains and in cancer of the breast, in cases in which other sedatives and narcotics have failed to give relief. The mode of application is by the satura- tion of folds of lint of the size of the part to which it is used, brought into close contact, then covered with three or four layers of lint, covered with oil-silk or spongio-pi- line wrung out of hot water. The application to raw sur- faces, of course, requires some care in manipulation. The strength of the solution is about four drachms to sixteen ounces of water. The addition of a small quantity of gly- cerine is advantageous.—Dr. W. B. Kasteven, Lancet. WHooping-COUGH.—Croton-Chloral,—I do not know if the administration of croton-chloral in whooping-cough has any originality; but, after a somewhat extended trial, I regard it as almost a specific. I have given it in gradually increasing doses, commencing with one grain twice or thrice a day, and almost without exception there has been a very marked reduction both in the violence and the fre- quency of the attacks,—Dr. Wm. Paulson, Lancet. New Antiseptic and Astringent Letion.—Salicylate of E I) IT' () [? I / J , A £35T IRA (T.S. 71 Iron.—Salicylic acid and its compounds are excellent anti- || Septic applications to wounds after operations, but like car- bolic acid they are not astringent, and therefore allow free capillary bleeding. A solution of salicylate of iron is both astringent and antiseptic.—Dr. Robert Kirk. SURGIcAL LIGATURES.–Carbolised Ligatures versus Tor- sion.—Of the vexed question of ligature or torsion. We have ceased at this hospital to use acu-pressure, because, after a satisfactory trial, we thought it decidedly inferior to the old plan of the silk ligature, and some of my col- leagues still use the latter. I have, as a general rule, abandoned it for the carbolized cat gut ligatures, which I have found equally efficient against primary and second- ary hemorrhage, and which offer (I am again speaking only generally) no obstacle to the rapid union of the wound. You saw this illustrated in the case of the little child whose thigh was amputated. The wound was healed almost entirely, and the patient out of bed, on the four- teenth day after the amputation, no trace of the ligatures having been seen. I prefer this plan to torsion (though quite admitting the efficacy and safety of torsion in skilful hands), inasmuch as it is very much easier to apply, and involves much less handling and contusion of the parts. In an amputation in which torsion is used, though the larger and more obvious vessels may be easily and quickly secured, we often see much difficulty in dealing with those which come less distinctly into view; and this difficulty is greater if the tissues are unhealthy. In such cases either the parts are left long exposed and are much handled— which cannot but retard union—or the smaller vessels are left to bleed; and even if this bleeding ceases without any serious damage to the patient, yet the blood must distend the flaps, some of it must remain as clot, even in spite of drainage, and it must in that way again retard union. | With the carbolised ligature each vessel can be perma- nently secured in a moment; and the small knots of gut 72 EDITORIA L AIBSTRACTIS. left in the wound do not seem in any way to affect the rapidity of its union. It is for these reasons that I prefer this form of ligature in amputation.—Mr. T. Holmes. Post-PARTUM HEMORRHAGE.-In post-partum hemor- rhage a drachm of laudanum will rally the exhausted strength, restore consciousness, rouse the uterus to action; and arrest the bleeding when six times ten minims in water would allow the patient to bleed to death. In syncope a tablespoonful of undiluted brandy will have an effect which twice the quantity drowned in water would fail to produce. We defeat a paroxysm of ague and cut short the disease, or suppress neuralgia, by a single large dose of quinine, when repeated doses of average amount have entirely failed,—Dr. W. H. Broadbent, Practitioner.