OF THE > .r ^iit»»«rsitg of ^aliloitnia. y ^ ^ Name of Book and Volume, 7ja Division Range Shelf. Received .87 A — j University of cdiioi aia. THE rvlEDICAL LIBRARY I I \'. J . I'( > r WCr 1: A I'D. .\I . I >. ■ Of San Francisco. PRESENTED BY MES. AND MISS FOURGEAUD. ri:intf tiiv. is:.;. THE DISEASES OF THE EAR. THE DISEASES OF THE EAR: NATURE, DIAGNOSIS, AND TREATMENT. JOSEPH TOYNBEE, F.R.S., FELLOW OF THE ROYAL COLLEGE OP SURGEONS OF ENGLAND; AURAL SURGEON Tu, AND LECTURER ON AURAL SURGERY AT, ST. MARY'S HOSPITAL; AURAL SUR- GEON TO THE ASYLUM FOR IDIOTS ; CONSULTING AURAL SURGEON TO THE ASYLUM FOR THE DEAF AND DUMB; AND CONSULTING SURGEON TO THE ST. GEORGE'S AND ST. JAMES'S GENERAL DISPENSARY, LONDON. AVITH ONE HUNDEED ENGRAVINGS ON WOOD. PHILADELPHIA: BLANCHARD AND LEA. 186 0. ^ C. SHERMAK A SON, PRINTERS, Corner SerentU and Cherry Streets, Philadelphia. y- I THIS VOLUME IS DEDICATED TO THE (Sobcrnors of St. Ularg's Daspital $011^011, WHO, BY ESTABLISHING AURAL SURGERY AS A DISTINCT DEPARTMENT OF STUDY IN THEIR HOSPITAL AND MEDICAL SCHOOL, EVINCED A DESIRE TO ELEVATE THE SUBJECT OF DISEASES OF THE EAR TO ITS DUE POSITION, AS A BRANCH OF PROFESSIONAL KNOWLEDGE BASED UPON CLINICAL OBSERVATION AND SCIENTIFIC RESEARCH. PREFACE. Ix preparing the i^resent work, it has been my aim to produce a practical treatise on the Diseases of the Ear, having for its foundation the anatomy, physiology, and pathology of the organ. This volume, however, does not profess to give a complete description of the structure and functions of the Ear: it will be perceived that the domains of anatomy and physiology have only been entered upon when requisite for the elucidation of the pathology or treat- ment. And now, after twenty years' labor, seeing this volume complete, I cannot but regret that it is not more worthy of its subject, and of the inteUigence of the Medical Profes- sion, to which it is addressed. It only remains for me to continue to devote myself to my labors. And thus, while I sincerely thank the numerous members of the Profession for their generous assistance, in supplying me with the larger part of the means of research which I have enjoyed, I beg stiU further to solicit their aid. Long engaged upon another work, in the shape of " lUustrations of the Pathology of the Ear," for which I possess a large amount of material, I nevertheless require much more. Indeed, even since this Vlll PREFACE. volume has been passing through the press, two recent spe- cimens, received from medical men in the country, have elucidated two entire series of preparations in my Museum.^ I need scarcely draw attention to the beautiful illustra- tions in this volume, which, with two or three exceptions, were drawn from nature, on wood, by Mr. Ford. Few references having been made in the body of this volume, to the investigations on wliic^i it is founded, I have given, in an Appendix, a list of my published papers, to- gether with their dates, so that the reader may refer to them when he thinks it desirable to do so. * It always affords nie much pleasure to show my Museum to medical men. 18 Savile Row, January 20, 1S60. CONTENTS. CHAPTER I. INTRODUCTION. PAGB Neglect of the study of the morbid anatomy of the ear, the cause of our igno- rance of aural surgery — Mode of investigating the diseases of the ear — Method of dissecting the ear, ........ 33 CHAPTER 11. THE EXTERNAL EAR. Anatomical observations — Use of the external ear — Effect of the removal of the external ear (case) — Pathological observations — Malformations of the external ear, with absence of the external meatus (cases) — Supernu- merary ears — Inflammatory diseases — Chronic erysipelas — Chronic ec- zema — Cysts — Tumors — Deposits — Malignant disease, .... 42 CHAPTER III. THE EXTERNAL MEATUS. ITS EXPLORATION. Anatomical observations — Osseous meatus — Membranous meatus — Objects in exploring the meatus — Means of exploration — Lamps — Speculum — Mode of exploration, .......... 57 CHAPTER IV. THE EXTERNAL MEATUS {continued). ON FOREIGN BODIES AND ACCUMULATIONS OF CERUMEN IN THE MEATUS. Foreign bodies in the meatus — Mode of removal — Cases — Ceruminous glands — Their diseases — Accumulations of cerumen — Their causes — Table of two hundred cases in which cerumen was removed — Symptoms — Effects — Treatment — Mode of removal — The syringe and its use — Cases, . GS X CONTENTS. CHAPTER V. THE EXTERNAL MEATUS {conilnued). THE DERMIS AND ITS DISEASES. PAGE 1. Acute inflammation : — a, Acute inflammation confined to the dermis — Treatment — Cases. 6, Acute inflammation extending to the brain and its membranes — Treatment — Cases. 2. Chronic inflammation : a, Chronic inflammation with hypertrophy and ac- cumulation of epidermis — Treatment — Cases, b, Chronic catarrhal in- flammation — Treatment — Cases. c, Chronic catarrhal inflammation, extending to the bone and to the brain — Treatment — Cases, d, Ulcera- tion, ............. 88 CHAPTER VI. THE EXTERNAL MEATUS {continned). POLYPI. Causes of polypus — Symptoms — Three species of polypus : 1. The cellular raspberry polypus — Structure — Treatment with potassa cum calce — Cases — Treatment by removal with the lever-ring forceps — Cases. 2. The fibro-gelatinous polypus — Structure — Treatment — Cases. 3. The globular cellular polypus — Structure — Treatment — Cases, . . .111 CHAPTER VII. THE EXTERNAL MEATUS {concluded). TUMORS. Osseous tumors — Structui-e — Two classes — Treatment — Cases — Molluscous tumors — Structure — Effects on the bone — Treatment — Case — Conclusion of the subject of the diseases of the external meatus — Tabular view of the morbid conditions found in the meatus exteruus in 1013 dissections, 13G CHAPTER VIII. THE MEMBRANA TYMPANL STUVCTURE AXD FUXCTIOXS. The epidermoid layer — The dermoid layer — The fibrous layers : — The radiate . fibrous lavcr — The circular fibrous layer — The mucous layer — Tensor liga- ment — Functions of the membrana tympani, . . . . .151 CONTENTS. XI CHAPTER IX. THE MEMBRANA TYMPANI {continued). PAGE The epidermoid layer — Dermoid layer — a, Acute inflammation — Treatment — Cases, b, Chronic inflammation — Cases, c, Ulceration — Cases. Fibrous laminae : a, Acute inflammation, b, Chronic inflammation, c, Ulceration. d, Calcareous degeneration, e, Relaxation of the membrana tympani — Treatment — Cases, 164 CHAPTER X. THE MEMBRANA TYMPANI {concluded). Perforation, causes — Physiological observations — Experiments previous to the formation of an artificial membrana tympani — On the artificial membrana tympani — The mode of applying it — Cases — Rupture of the membrana tympani — Physiological observations — Pathological observa- tions — Cases, . . ^ 18G CHAPTER XL THE EUSTACHIAN TUBE. Anatomical observations — Physiological observations — Pathological observa- tions — Seat of obstruction in the Eustachian tube: — 1, The faucial ori- fice. 2, The tympanic orifice. 3, Middle part. — Causes of obstruction : — 1, Thickened mucous membrane. 2, Relaxed mucous membrane, a, Obstruction of the faucial orifice from thickened mucous membrane — The exploration of the tube — The otoscope — Treatment — Use of the Eustachian catheter and of the explorer — The excision of the tonsils — Cases. &, Obstruction of the Eustachian tube at its faucial orifice from relaxed mucous membrane — Symptoms — Treatment — Cases, c, Obstruc- tion of the Eustachian tube at the tympanic orifice from thickened mucous membrane — Symptoms — Treatment — On the operation of puncturing the membrana tymj^ani. d, Obstruction of the middle part of the Eustachian tube by mucus, by stricture, or by membranous bands, .... 213 CHAPTER XII. THE CAVITY OF THE TYMPANUM. Anatomical observations — Pathological observations — Diseases of the mucous membrane : — a, Congestion. b, Acute inflammation — Affecting the portio dura nei've — Extending to the brain — Scrofulous matter in the tympanic cavity, c, Chronic inflammation. J, Chronic catarrhal inflam- mation, e, Chronic catarrhal inflammation extending to the bone, dura mater, or brain, yj Ulceration of the mucous membrane, . . . 248 Ml CONTENTS. CHAPTER XIII. THE CAVITY OF THE TYMPANUM {concluded). Page a, Rigidity of the mucous membrane — Cause of deafness in advancing years — Treatment — Cases, h, The formation of bands of adhesion, c, Anchy- losis of the stapes to the fenestra ovalis — Pathological observations — Treatment — Cases, d, Disconnection of the incus and stapes — Physiolo- gical observations — Pathological ob.sf:rvations — Cases, .... 288 CHAPTER XIV. THE MASTOID CELLS. Anatomical observations — a, Diseases of the mastoid cells in childhoo^l — Cases of the disease advancing to the bone and the cerebrum. 0, Diseases of the mastoid cells in the adult — Acute inflammation of the mucous membrane — Chronic inflammation of the mucous membrane — Purulent infection — Symptoms of remittent fever — Caries of the lateral sulcus — Abscess in the cerebellum, c, Necrosis of the mastoid process — Paralysis of the portio dura nerve — Treatment — Opinion respecting life insurance in cases of discharge from the ear, 321 CHAPTER XV. THE DISEASES OF THE NERVOUS APPARATUS OF THE EAR, PRODUCING WHAT IS USUALLY CALLED "NERVOUS DEAF- NESS." a. Diseases in which the ear alone is affected : — 1. From concussion — Three modes — Blows on the ear — Loud sounds — Falls. 2. From the applica- tion of cold — Cold air — Cold water. 3. From the effect of morbid poi- sons — Rheumatic fever — Typhus fever — .Scarlet fever — Mumps — Gout. h. Diseases in which the brain, as well as the ear, is affected : — 1. Mental excitement — Over-study — Sorrow. 2. Bodily Debility — Want of sleep — Accouchements — Over-exhaustion in hot climates — Fasting — Nen- ralgia, ............. 367 CHAPTER XVI. THE DISEASES OF THE NERVOUS APPARATUS {concluded). Ulceration of the membranous labyrinth — Caries and necrosis of the petrous bone, 392 CONTENTS. Xm CHAPTER XVII. MALIGNANT DISEASE OP THE EAR. PAGE Origin in the mucous membrane of the tympanum — Destruction of the petrous bone — Sometimes mistaken for polypus — Operations to be avoided — Brain and dura mater involved — Treatment, 404 CHAPTER XVIII. ON THE DEAF AND DUMB. Diseases producing deaf-mutism — The condition of the ears in the deaf and dumb, as ascertained by examination during life — The condition of the ear in the deaf and dumb, as revealed by dissection — The mode of exami- ning a child supposed to be deaf and dumb — On the medical treatment of the ears of the deaf and dumb — The amount of hearing possessed by chil- dren usually accounted deaf and dumb — On the education of the deaf and dumb, with cases, 413 CHAPTER XIX. EAR-TRUMPETS AND THEIR USE, 435 APPENDIX. List of published papers on the Structure, Functions, and Diseases of the Ear, 437 LIST OF ILLUSTRATIONS. 1. Cvttiag Foreeie, 49 2. MalfonMdrigktSxtemlEaroraehiU, 4T 3. The i»di» ft» iy Memtas Aw dit ot ia a Bxteiwgof » AiM, ia the fiti^rf a fawre pMtoior to the Coadjkid Tnxeas, 48 4. The Tjaqpaaie CkTitj, with the Baalachiaa tabe oprmimg iato its aaterior aad jafieriar part, .41 3. Badtoeataiy Extoaal Eais . M C. HcBatoede of the Ezteraal Ear (Wilde . M 7. TaMoroftheLobafefWlMe), ... 55 8. ArerticalsectiflBal'thefcft MeatasExtexaos, firABmiihoat iA«aE\i£, 57 9. The Oiifice of the Meatas Bxtciaas, Bhewiag it> onal ihape, .... 59 19. The Obbhms Meatas Bxtcfaas of aa ia&at, M 11. The Mode of eaaMia ia g the Ear hy aid of gaaligtrt^ 62 12. Mfliex's l^mp, o|Ma, .... S3 13. MiDeT's LaaiVk doeed, 63 14. A get of Spccala feg the pai jw u e rf eT^Miaia g the Bne»aal Meatai^ 65 13. The Sargeea >»«»i»i»g the ExteroAl 3Ie«£iij hr means of ICIlier** Lamp aifi the Tabalar ^ceala^ 66 16. Bectaagalar Foreefe, . T2 17. The Exteiaal Meatas gtcatljr dilated bj a piece of cottoa-voolT 73 18. CcraMeaiacoatactwiththe oatcr sai&ce of the McadbfaaaTjraqnai, 86 19. Meatas greatly dilated hjr etxmmtm, 81 29. Aatcnor wall of the Oaeoas Meatas partlj aheorited, foDowiag the |hi wan of aa aecasalatioa of cciaaea, 81 31. Ccraaea pttf j cctii ^throaghthe Mealmua TrBpam iato the Tjvpaaie Csritj, 82 23. Syrii^e aad Soxiie, 83 33. Ear-spoat, tkted oa the head, 8ft 24. Epidenus firaa the Exteiaal Meatas ia the foim of a tahalar cal de g a c, aad a lajer anaagcd cirealaiiy, 9T 35. The latoaal Sai&ce of the Teapofal Boae, Aaaiag two oiifc.** la the Lateral Siaas, filed hj ttramtm : aad also the caiioas Saleas LatenliB, . . 165 36. The Exteiaal SaiCace of the Temporal Boae, Aorwi^ a caxioai po»tii« cxtead- ii^ &oai the Mastoid Procea to the loot of the Zjgoaatie Plroces. 196 27. Baspheny CeOalar Poljpas, 112 28. C^alar straetaie of the Ba^heny Peljpasy 113 29. A large Baspheny Poljpas, Tiable at the oeifiec of the Meatas, 113 39. TheSaareofMr. WOde, . 119 31. The Lerer-riag Forceps, opea, 119 32. The Lerer-riag Fotccpo holdiag a Polypas, 131 33. FiW»-gelatiBoas Paijpw, 133 LIST OF ILLUSTRATIONS. XV FIO. 34. Structure of the Fibro-gelatinous Polypus, 35. The Ring Forceps 36. Globular Cellular Polypus, 37. Two Osseous Tumors projecting from the walls of the Meatus Externus, . 38. The vertical section of the External Meatus and Osseous Tumor, 39. Three Osseous Tumors projecting from the walls of the Meatus, 40. A large Osseous Tumor and two smaller ones in the Meatus Externus, 41. Two Osseous Tumors of the External Meatus in contact internally, . 42. An Osseous Tumor growing from the Upper Wall of the Meatus, 43. Osseous Matter developed from the walls of the Meatus Externus, 44. Molluscous Tumor filling the whole of the Meatus Externus, . . . . 45. Cavity in the Meatus Externus from which a Molluscous tumor has been removed, 46. Apertures in the upper wall of the Meatus Externus communicating with the Cerebral Cavity, produced by a Molluscous Tumor, .... 47. The Triangular Shining Spot at the anterior and inferior part of the surface o the Membrana Tympani, ......... ^8. The Dermoid Layer of the Membrana Tympani continuous with the Dermis lining the upper wall of the Meatus Externus, ...... 49. The Radiate Fibrous Layer of the Membrana Tympani, .... 50. The Fibres composing the Radiate Fibrous Lamina (magnified), 51. The Radiate Fibrous Lamina, 52. The Radiate Fibrous Lamina, after having been treated with Acetic Acid, 53. The Circular Cartilaginous Band, after having been treated by Acetic Acid, 54. The External Surface of the Circular Fibrous Lamina (slightly magnified), 55. The Internal Surface of the Circular Fibrous Lamina (slightly magnified), 56. The Fibres composing the Circular Fibrous Lamina, ..... 57. The Fibres of the Circular Fibrous Lamina, treated with Acetic Acid, 58. The Radiate Fibrous Lamina, the Circular Fibrous Lamina, and the Mucous Membrane of the Membrana Tympani (slightly magnified), . 59. The Attachments of the Tensor Tympani Ligament (slightly magnified), . 60. Epidermoid Layer of the Membrana Tympani hypertrophied (magnified), . 61. Granulations on the surface of the Dermoid Layer of the Membrana Tympani 62. The Membrana Tympani fallen in towards the Promontory (seen in section), 63. The Membrana Tympani fallen in towards the Promontory (seen from without), 64. An Orifice in the Membrana Tympani produced by ulceration of the Fibrous Laminae, ............. 65. The Fibrous Layers of the Membrana Tympani ulcerated over a small extent at its anterior part, ............ 66. Calcareous Deposit in the Circular Fibrous Lamina of the Membrana Tympani, 67. Calcareous Deposit in the Radiate Fibrous Lamina of the Membrana Tympani, 68. The whole of the Membrana Tympani converted into Calcareous Matter, . 69. The Artificial Membrana Tympani, ......... 70. Margin of the circumference of the Membrana Tympani remaining after the destruction of the rest of the membrane, ....... 71. Handle of the Malleus remaining after the destruction of the Membrana Tympani, 72. Body of Malleus remaining after destruction of Membrana Tympani, 73. Surgeon introducing the Artificial Membrana Tympani, 74. An Aperture in the lower part of the left Membrana Tympani, from rupture, 75. An Aperture in the posterior part of the right Membrana Tympani, from rupture, 76. An Aperture in the right Membrana Tympani, 77. The Otoscope, 78. The Surgeon using the Oto.«cope, ......... 79. The Explorer, and the Eustachian Catheter into which it fits, . . . . PAGE 124 126 130 136 137 141 141 143 144 145 148 148 149 152 153 155 156 156 157 157 158 159 159 160 160 161 164 171 175 176 176 177 179 179 180 191 191 192 193 194 208 209 210 221 222 227 X\n LIST OF ILLUSTRATIONS. FIG. PAGE 80. The Surgeon using the Eustachian Catheter and the Explorer, .... 228 81. Stricture of the Eustachian Tube 247 82. An antero-posterior vertical section of the Temporal Bone through the Tympa- nic Cavity and Mastoid Cells, 249 83. The upper Osseous Wall of the Tympanum defective, 250 84. The Canal for the Portio Dura Nerve at the upper part of the Tympanic Cavity incomplete, ............. 260 85. The Internal Surface of the Temporal Bone, the Tympanic Cavity diseased, . 283 86. The lower Osseous Wall of the Tympanum incomplete 286 87. The Orifice seen from the Jugular Fossa 286 88. Membranous Bands connecting the Ossicles, . ...... 295 89. Membranous Bands connecting the Ossicles to the Promontory (magnified), • 296 90. The whole of the Circumference of the base of the Stapes anchylosed to the Fenestra Ovalis, the Crura detached, 299 91 . Base of the Stapes expanded, and osseous matter thrown around it and the Crura, 299 92. Expansion of the base of the Stapes, and its protrusion into the cavity of the Vestibule (magnified), ........... 300 93. Expansion of the Vestibular Surface of the Articulation (magnified), . . 300 94. The External Surface of the Temporal Bone of a child, 322 95. A Vertical Section of the Temporal Bone of a child through the horizontal por- tion of the Mastoid Cells, 323 96. The External Surface of the Temporal Bone, showing the irregular-shaped carious portion of bone above the Meatus, ........ 326 97. A Vertical Section of the Diseased Bone, . . . • . . . . . 327 98. The right Petrous Bone, showing the carious condition of the Sulcus Lateralis, 346 99. Caries of the External Semicircular Canal, ....... 398 ]nn. Carious Temporal Bone, 409 THE DISEASES OF THE EAR. CHAPTER I. INTRODUCTION. NEGLECT OF THE STUDY OP THE MORBID ANATOMY OF THE EAR, THE CAUSE OF OUR IGNORANCE OF AURAL SURGERY — MODE OP INVESTIGATING THE DISEASES OF THE EAR — METHOD OF DISSECTING THE EAR. As introductory to this work on the Diseases of the Ear, I may be pardoned the observation, that the subject has hitherto been too much regarded, by the great mass of the profession, as a blank in Medical Science ; indeed, to quote from Mr. Wilde's introduction to his valuable treatise on Aural Surgery, medical men are too ready to affirm that " they know nothing about the diseases of the organ of hearing ;" and many, looking upon the difficulties that surround the investigation as insurmountable, have tacitly aban- doned its pursuit. Yet, if we carefully survey the history of the rise and progress of Aural, as a distinct branch of Scientific Sur- gery, one main cause of the disrepute into which it had fallen may be traced to the neglect of the pathology of the organ of hearing — a neglect that doubtless led also to the ignorance which has pre- vailed as to the structure and functions of some of the most impor- tant of its parts. It is a question, however, Avhether the inherent difficulties of Aural Surgery arc of a nature to prevent its being as thoroughly understood as the other branches of surgery. This question has been answered in the affirmative by some, on the ground of the deep and hidden situation of the larger part of the organ, and the extreme 3 34 THE DISEASES OF THE EAR. intricacy of its structure. But surely the organ of hearing is not so much concealed from view as several others (the heart, for in- stance), of whose diseases "we have a very clear knowledge ; nor is its structure more complicated than that of the eye. The result of my own experience, and I think also of those who have carefully attended to my practice at St. Mary's Hospital, is, that the diseases of the ear are not more difficult to diagnose, nor are they on the whole less amenable to treatment, than those of the eye, the joints, or almost any other organ that can be named. When my attention was first turned to the study of the diseases of the ear, I resolved to prosecute researches into the pathology of the organ. From that time to the present, I have made nearly 2000 dissections ; and although it must be manifest that this number is small, compared to that which is required for the thorough elucida- tion of the subject, still I feel it is a sufficiently solid foundation upon which to build a rational system of Aural Surgery. Fully a}vare of the difficulties in the way of procuring specimens from those deaf persons who had been inspected during life, and whose histories had been recorded, I determined at once to dissect every ear that I could obtain, in order to ascertain Avhat arc the most common morbid conditions to which the organ of hearing is subject ; in fact, to secure one step first, by ascertaining something of the morbid anatomy of the ear, before advancing to a consideration of its pathology. The result of my investigations established this general fact, that the existence of some of the most important affec- tions of the ear had not even been imagined. Having advanced thus far with the morbid anatomy of the ear, my next step was to pursue its pathology. This was effected, in the first place, by prose- cuting inc^uiries into the history of the patients whose ears were found to be diseased ; secondly, by dissecting the ears of deaf per- sons supplied to me by medical men, and comparing the morbid appearances observed with the notes accompanying the cases ; and thirdly, by availing myself of the opportunity, during some years, of inspecting all the ;leaf persons in an institution containing more than 2000. individuals, of recording their cases, and then of making dissections of the organ of hearing in those who died. By these means, and by the facilities offered at the public institutions to which I have been attached, of conducting post-mortem inspections of the patients attended by me, I have been able in many cases to compare the symptoms occurring during life, the appearances of the organ. INTRODUCTION'. 35 and the history of the case, with the morbid structures found after death. 3Iode of investigating the Diseases of the Ear. — The following plan for eliciting all the important particulars with which a surgeon ou^ht to be acquainted Avhen endeavering to form a diagnosis of dis- ease of the ear, has been pursued by me during many years. Its use involves no great time or labor ; and as it is desirable that it should be observed by those studying the subject, I will describe it in detail. I. The age and occupation of patient. II. State of health, temperament, condition of pulse, &c. III. If any relations are deaf, name them. IV. History of the affection ; duration ; supposed cause. Former symptoms : if at any time pain in the ears or head. Nature of jyro- gress : whether rapid or slow ; if it has increased by sudden parox- ysms, or by imperceptible degrees. Present symptoms : if pain, noises, or discharge ; amount of hearing power as shown by conver- sation ; whether the patient require to be spoken to distinctly in a room, or within the distance of a yard, or close to the ear : which ear is the worse. Causes aggravating the deafness : a cold, cold or moist weather, bodily fatigue or mental excitement, the act of mas- tication. Causes producing imp)rovement : improved health, dry air, a cold, cold weather, warm weather. V. Result of examination. Right ear. The distance at which the watch is heard. ^ 3Ieatus : quantity and condition of the cerumen ; state of the dermis and of the osseous wall. Memhrana tympani : surface dull or shining, transparent or opaque, state of the triangular bright spot , if more or less concave than natural. Eustachian tube : if air is heard by means of the otoscope to enter the tympanic cavity naturally during deglutition, the nose and mouth being closed ; if the air is heard to enter the tympanic cavity natu- rally during a forcible attempt at expiration with the nose and mouth held closed. Left ear : ditto. State of mucous membrane of the fauces. ' The medical man should ascertain the distance at which his watch is usually heard by persons whose hearing power is supposed to be perfect. The hearing distance with mj- own watch is about three feet. The wiitch should be gradually brought towards the ear instead of being withdrawn from it. 36 XnEDISEASESOFTHEEAR. VI. Previous treatment. VII. Diagnosis. Although this enumeration of all the points Avhich require filling up, might lead to the idea that the use of this i)laii must be attended ■with considerable trouble in actual practice, it will be found other- wise, as numerous abbreviations may be resorted to. For example, take the following case. F. R., set. 43, architect. H. (health) : tolerable, but subject to attacks of sore throat. R. D. (relations who are deaf) : A brother and sister were both deaf when young, but quite recovered before reaching the age of 20. H. (history) : "When a boy, suffered from ear-ache, which was often followed by deafness and sometimes by discharge from each ear. Subsequently the attacks of ear-ache ceased; but he has ever since been subject to fits of deafness which have usually come on durinrana tyuiiiani ; and secondly, because it has been found impossible to keep the aperture in the integuments from closing. In most cases of deformity of the external ear and meatus, a peculiar s(|uare shape of the face has been observed, the lower jaw being very THE EXTERNAL EAR. 51 short ; and there is also not imfreqiiently imperfect speech and de- glutition. Thus in an infant, a month old, seen in consultation Avith Mr. Roberts, of St. John's "Wood, 1853, the meatus auditorii being entirely absent, and the auricles only partially developed, the chin receded much more than natural, and there was a not unfrequent regurgitation through the nose of the contents of the stomach during eructation. Supernumerary ears. — Cases have been recorded in which more than two ears have existed. Mr. Wilde says, that Cassebohm relates the case of a child with four ears ; two placed naturally, and two lower down in the neck : in this instance, there were two petrous portions to each temporal bone. II. Inflammations of the external car. The two kinds of inflammation to which the auricle is subject are erysipelas and eczema. Chronic Erysipelas. — It is unnecessary here to speak of the acute form of erysipelas, since in its nature and treatment it does not differ from the same disease attacking other parts of the bod3^ The chronic form of erysipelas, however, deserves attention on account of its frequency, the discomfort it produces, and its very tedious character. It sometimes originates in the acute form of the disease, and often remains during many years. By degrees the aviricle be- comes hypertrophied and hardened, the meatus not unfrequently closed, and the ear loses its natural form, its surfiice being exceed- ingly tender. This affection generally occurs in females beyond the middle period of life. Case. — C. F., aged 49, admitted under my care at the St. George's and St. James's Dispensary, in 1849. She complains of much tenderness in both external ears, which, on examination, are observed to be red and very much thickened ; the integument and subjacent cellular tissue of the right ear are hardened, and the auricle scarcely presents the general form of the natural organ. The patient's health was much deranged. A solution of nitrate of silver, two grains to the ounce, was applied to the ear, and mild preparations of steel were administered. Under this treatment the tenderness of the ear greatly diminished. Chronic Eczema, like chronic erysipelas, is most frequently found in females beyond forty years of age, in whom there is some consti- tutional debility ; it is, however, often met with in children. It is generally accompanied by extreme irritation of the auricle, which is 52 THE DISEASES OFTHE EAR. of a deep-red color, and often very smooth and shining. Scales of epidermis arc seen adhering to some of the parts, and from others a thin discharge exudes. In some cases, especially in adults, the dermis is hypertrophied, and the auricle loses it natural aspect. If necrlected, it is liahle to extend into the meatus, the dermoid layer of which also becomes red and sensitive, and sometimes tumefied, although not unfrequently no tumefaction is apparent ; the dermoid layer of the meatus throws out a discharge very similar to that formed on the external ear ; and sometimes the epidermis collects in quantities so large as to obstruct the canal, and give rise to those symptoms of pressure on the membrana tympani "which Avill be more particularly alluded to under the diseases of the meatus. The treat- ment of chronic eczema is very similar to that of chronic erysipelas. Frequent ablutions with tepid water, combined with emollients, should be practised in the early stages of the affection, when the skin is very sensitive, and the latter should be protected from the air by oiled silk, or very thin vulcanized India-rubber. Afterwards, mild astrin- gents are to be used, and, as Mr. AVildc recommends, a solution of gutta-percha in chloroform may be painted over the surface several times until a complete coat has been formed ; which is to be renewed from day to day, as often as it peels off. The head should be kept cool ; and instead of the ears being studiously covered by layers of warm material, they should be exposed as freely as possible, and very soft pillows avoided. The meatus ought to be frequently syringed Avith tepid Avater, for the purpose not only of removing the dead cuticle and discharge, but also of soothing the irritable dermoid membrane. The introduction into the meatus of ear-picks and other foreign bodies, for the purpose of allaying the itching of tube, must be studiously avoided ; but if the itching becomes ver\' distressing, a vapor-bath and hot injections should be resorted to. In later stages of the affection, when both dermis and epidermis become thicker than natural, the ungucntum zinci or the unguen- tum hydrargyri nitratis may be employed. In addition to local applications, constitutional remedies should be employed. In adults any derangement of the general system should be attended to, alter- ative medicines administered, and great attention to diet enjoined, as well as abundant exercise in the open air. In cliildren, these constitutional remedies require to l)e still more sedulously used, and where there is a tendency to glandular enlargement, sea or country air may be advantageously recommended. THE EXTERNAL EAR. 53 In addition to the two kinds of inflammatory disorder just noticed, the auricle is sometimes subject to a chronic inflammation, the seat of which appears to be the cartilage or its immediate invest- ment : it is characterized by slight congestion and by extreme sensi- bility upon pressure. The auricle is also often the seat of chronic inflammation accompanied by excoriations ; but frequent ablution Avitli tepid water and the use of mild astringents generally cflect a cure. III. Ci/sts, Tumors, Deposits, and Malignant Diseases. Cysts. — The only kind of cyst to which the external ear is sub- ject, is that formed by an efi"usion of blood between the cartilage and the integuments. It has most generally been found in insane persons ; and according to ni}^ friend Dr. Thurnam, of the Wilts County Asylum, who has paid particular attention to the subject, and who has favored me with his experience upon it, it is not now so prevalent as formerly. This he ascribes to the fact that less personal violence is now used. It has been thought by some to be peculiar to the insane ; such, however, is not the case, for a patient with this afiection was admitted under my care, in the year 1852, at St. Mary's Hospital, and one, if not two, other cases of the kind have presented themselves to me. This disease, called by Dr. Stifi",^ Hsematoma Auris, is divided by him into four stages. 1. The stage of hyperemia, and probably chronic inflammation, as shown by the congestion and loss of the elasticity of the carti- lage. 2. The stage of efi'usion ; an apoplectic layer is suddenly formed, causing obliteration of the ridges and depressions of the ear. 3. The cystic stage ; in a comparatively short time absorption commences, the ridges reappear, but in altered shape. This stage may last for years. 4. Permanent induration, complete absorption of the fluid ; and occasionally atrophy of the ear. Dr. Thurnam calls this disease " Hsiematocele of the external ear." In a letter to me on the subject, he says: "In the first stage of this affection, I believe an effusion of blood exists between the folds of the integuments and around the fibro-cartilage of the ear : if punc- tured in this stage, there is a discharge of serum of the blood, mixed ' Medico-Chirurgical Review, January, 1858. 54 THE DISEASES OF THE EAR. with coagulum. I tliink, liowcver, the proper practice is, )iot to puncture in this early stage, but to apply evaporating lotions. Even under this treatment, though still more if left to itself, the tumor Fig. 6. Hematocele of the External Ear (AVilde). often increases so as entirely to disfigure the ear, and produces a large hot swelling of a livid red color. At the end of a week or two, according to circumstances, I have passed, with a common or curved needle, a small seton through the long axis, pressing out the contents, Avhich are now, in addition to their sanguineous nature, more or less purulent, and allowing the rest to escape gradually. At first the diminution of the tumor is trifling ; but under the use of the seton it gradually subsides, and at the end of two or three weeks a certain amount of chronic thickening only remains. Where no such treatment has been adopted, the resulting deformity has been very marked, and has continued through life." The patient who came under my notice, at St. Marj^'s Hospital, was a man aged 26, a boxer, who had received a blow on the ear a fortnight previously. The cyst was about the size of a small wal- nut ; it had been punctured, and a transparent fluid was evacuated; it had, however, soon formed again. lie did not return to undergo any treatment. THE EXTERNAL EAR. 65 Tumors. — The lobule of the external ear is subject to hyper- trophy, and to the development of tumors in its substance. Tumors are also developed from the surface of the cartilage, or from the cellular tissue coverino; it. Tumor of the Lobule (Wilde) . Mr. Wilde relates a case of tumor in the substance of the lobule. " M. S., a female, aged 19, has a hard, firm, ovoid tumor occup3ang the centre of the lobe on each side, but largest on the left. It is of a stony hardness, and is quite distinct both from the cartilage above and the fleshy part of the lobe, which it appears to pass through. The skin covering it is smooth, and of a light pinkish hue, like that of a keloid tumor. It grew gradually from the orifice made for holding the ear-ring, and has been several months attaining its present size. The tumor upon the opposite side, which also surrounds the hole made for the ear-ring is much paler in color, and not larger than a garden pea. The girl states she expe- rienced a great deal of pain and soreness in the wounds made in piercing the ears, and that about three or four months afterwards, she was obliged to remove the ear-rings, on account of the irritation they produced. The large tumor was dissected out, and the ellip- tical aperture left in the lobe brought together with sutures. It healed kindly, and the disease did not return. A section of the 56 THE DISEASES OF THE EAR. tumor exhibited a dense yellowish-white fibrous appearance, and was so hard that the nail made no impression upon it." Gouty deposits are not unfrequcnt in the external ear. Scirrhus. — Kramer, in his work on the Diseases of the Ear, devotes a section to the consideration of a disease which he entitles "scirrhous degeneration of the auricle." In its early stances, he describes its symptoms as analogous to those of erysipelas. As the disease advances, excoriation and ulceration of the auricle takes place, and the cartilage is perforated and destroyed. The auricle becomes nodulated and misshapen ; the nodules ulcerate. I have not met with the disease unless when complicated with disease of the petrous bone. Dr. Kramer cites three cases of supposed scir- rhous degeneration : of these the following occurred in the practice of Dr. Fischer : — A countryman, when eight years of age, perceived an itching, which depended on a scabby eruption of the head. This extended to the right ear, and its irritation being increased by roughly rubbing it Avith the hand, the skin Avas corroded. A redness and swelling of the ear, the certain attendants of inflammation, continued from that time, much encouraged by the plethora and strength of the individual. The disease now remained stationary for some years, but at the time of manhood it broke out afresh, and with increased intensity. During his twentieth year, it had ac- quired so enormous an extent that the whole auricle was converted into a knotty, deformed, and lumpy mass, in which the natural projection could scarcely be detected. At the anterior and inferior extremity of the antihelix the degenerate mass had begun to sup- purate. Dr. Fischer cut away with a knife the whole degenerated ear, and the wound healed in less than six weeks. CHAPTER III. THE EXTERNAL MEATUS— ITS EXPLORATION. ANATOMICAL OBSERVATIONS — OSSEOUS MEATUS — MEMBRANOUS MEATUS OBJECTS IN EXPLORING THE MEATUS — MEANS OP EXPLORATION — LAMPS — SPECULUJI — MODE OP EXPLORATION. The external auditory meatus is a tube formed partly of cartilage and partly of bone. It extends in a transverse direction from the concha of the outer ear to the membrana tympani internally. Its length varies in the adult from an inch and a quarter to an inch and a half. The Osseous Meatus. — There is a convexity about the middle of the lower wall of the osseous meatus which causes a slight central contraction of the calibre of the tube ; and this convexity, combined Avith a similar one in the anterior wall, often prevents the anterior and inferior fourth or fifth of the membrana tympani being visible Fig. 8. A vertical section of the left Meatus Externus, from without inwards. to the surgeon during his exploration. The superior and posterior walls are slightly concave : the anterior Avail and floor of the meatus extend three or four lines further inwards ; and as the membrana 58 TIIEDISEASESOFTHEEAR. tjmpani is attached to the inner extremity of each wall, hence the obli(iuc position of this membrane. The upper wall has intimate relations with the cerebral cavity ; the posterior is separated by a thin lamina of bone only from the mastoid cells ; the anterior wall forms part of the glenoid cavity and the fossa parotidea. The outer orifice of the osseous meatus is of an oval shape, its longer axis being from above downwards, and slightly backwards. The ante- rior and inferior parts of the orifice are rough and scabrous, the fibro-cartilage of the meatus being firmly inserted into them. The posterior and superior parts of the orifice are smooth, and perforated by numerous orifices for the transmission of vessels. The inner ori- fice of the meatus is round, and in the groove of its margin the cir- cumference of the membrana tympani is inserted. The diameter of the external meatus varies much. In some adults, it is so large as to admit the introduction into it of the end of the little finger for a considerable distance, and the membrana tympani may be seen by means of tlie ordinary daylight, without the lobe being drawn back. In other persons, the meatus is so small as scarcely to admit a common goose-quill. The large size of the meatus depends generally upon the original conformation of the bony tube, but its contracted state is often the result of osseous development, or a thickened condition of the dermis, or the presence of bony tumors. The membranous meatus consists of the following lamina?, begin- ning internally : — 1st, the epidermis ; 2d, the dermis ; 3d, the peri- osteum. Between the dermis and the periosteum of the outer portion of the tube are placed fibro-cartilage, cellular tissue, and ceruminous glands. The c])idermis forms a cul-de-sac, which covers the whole of the outer surface of the dermis, and is prolonged over the outer surface of the membrana tympani, of Avhich it forms the outermost lamina. In the outer part of the tube the epidermis is thick, and is perforated by the ducts of the ceruminous glands. Near to the outlet, it presents orifices for the passage of the hairs which fre- quently protect the entrance of the meatus. At the inner half of the tube, the epidermis is extremely thin, with a shining surface. The scales which compose the epidermis are constantly throAvn off from the free surface of the membrane : they mix with the cerumen, and in the healthy ear are excreted with it. The dermis also forms a cul-de-sac by being continuous with the dermoid layer of the membrana tympani. Near to the orifice of the meatus, the dermis differs but little from that covering the cartilage THE EXTERNAL MEATUS ITS EXPLORATION. 59 of the concha, Avith the exception that it gives insertion, particularly in elderly persons, to numerous short strong hairs. More internally, the dermis is remarkable for its extreme sensibility, and gives pas- sage to the ducts of the ccruminous glands. The outer half of the dermis is firmly connected, anteriorly and inferiorly, to the fibro- cartilage ; posteriorly and superiorly, where there is no fibro-carti- lage ; the dermis is connected to the superior and posterior parts of the osseous meatus by loose cellular tissue, in which the ceruminous glands are placed. At the inner half of the tube, the dermis is intimately connected with the periosteum, the two membranes being frequently inseparable. The outer half of the membranous meatus contains, in addition to the laminte previously noticed, fihro-cartilage, which is continuous externally with that forming the external ear, and, internally, is attached to the rough margin of the osseous meatus by fibrous tissue, which admits of considerable motion taking place between the car- tilage and the bone. The outer part of the fibro-cartilage of the meatus projects and forms the tragus. The fibro-cartilaginous meatus Fig. 9. The Orifice of the Meatus Externus, showing its oval shape. does not form a complete tube, being deficient at its posterior and supe- rior third, where the bloodvessels of the bone freely communicate with those of the meatus. The shape of the orifice of the meatus, consist- ing of fibro-cartilage, is more oval than that of the osseous meatus, and is composed, anteriorly and inferiorly, of the fibro-cartilage, covered by the dermis, posteriorly of the anterior border of the 60 THE DISEASES OF THE EAR. concha, which projects slightly foi'Avards. The superior part of the orifice does not contain any fibro-cartilage ; Init in the remaining portions, the dermis is connected with the fibro-cartilage by very dense cellular tissue. That the orifice of the meatus externus is oval i.s shown by simply introducing the index finger within it in the living subject. It will be found that the finger (itself of an oval shape) enters some slight distance, and that its anterior and posterior surface are in contact with the corresponding surfaces of the orifice ; but if the posterior surface of the finger be directed upwards, and the anterior downwards, its entrance is impossible. The orifice of the external meatus is its narrowest part, and its cavity and the membrana tympani are guarded by the slight projection posteriorly of the tragus, while the posterior margin of the orifice projects slightly forwards. Thus the introduction of a foreign body is pre- vented by the flap of the tragus covering the orifice ; and if that be pushed aside or penetrated, then the projecting posterior border of the orifice directs the body against the anterior wall of the meatus. This condition of the orifice of the meatus is also of great use in preventing the sudden rush of cold air to the surface of the mem- brana tympani, and the passage of water to it, when the head is immersed, or copious ablutions are practised. The projection of the tragus backwards, and of the cartilage forming the posterior margin of the meatus forwards, consequently gives a curved form to the tube, which curvature is increased by the direction of the osseous tube being first slightly forwards, then backwards, and lastly, somewhat forwards again. Fig. 10. The Osseous Meatus Externus of an infant. At birth, only the rudiments of the osseous external meatus are present : these consist of a delicate osseous ring, which, however, is THE EXTERNAL MEATUS ITS EXPLORATION. 61 incomplete at tlie upper fourtli, where the surface of the temporal bone is smooth and slightly concave. The upper part of the mem- branous meatus rests on this portion of bone. The inner margin of the remainder is attached to the annulus auditorius ; its outer sur- face is in contact "with the adjacent tissues. As the child grows, the smooth superior surface is gradually developed into the concave upper wall of the meatus, and from the osseous ring spring the ante- rior, posterior, and inferior walls. In the exploration of the meatus, the object of the surgeon is threefold. I. To render the meatus as straight as is practicable. II. To dilate slightly the outer membranous and cartilaginous portion. III. To throw as much light as possible on the walls of the meatus. To straighten the meatus it is necessary to press the tragus for- wards, and the cartilage forming the posterior wall of the meatus backwards. When the meatus is very large, this may be accom- plished by simply pulling the outer ear backwards by the finger and thumb, at the same time that the tragus is pressed forwards by another finger ; but this is better effected by the aid of the speculum auris, which at the same time dilates the orifice. Some writers have supposed that it is not desirable to use any instrument for this pur- pose ; but the orifice of the meatus is generally so small that it is important to dilate it as Avidely as possible without causing pain, in order to allow the passage of a sufficient volume of the rays of light to permit the inspection of the surface of the meatus, and of that of the membrana tympani. That the orifice of the meatus is suscep- tible of being dilated is shown by placing the end of a finger in it, and then pressing it gently inwards, when the walls will be felt to yield slightly, and to embrace the finger firmly. For the proper inspection of the meatus a strong light is required, which can be so thrown as thoroughly to illuminate the visible sur- faces of the meatus externus and the membrana tympani. Sunlight is the best ; but as its presence in om" variable climate can rarely be made available, and as the surgeon must be prepared to make his observations at all times of the day and night, and often on patients lying in bed, it is clear his usual resort must be to artificial light. By a careful use of this light, however, he may, with few exceptions, attain to such a knowledge of the condition of the surfaces illumi- nated as will suffice for his guidance. 62 THE DISEASES OF THE EAR. There are two lamps ■\vliicli throw a good light into the meatus, M. Segalas's and Mr. Miller's. iSiyahiif' s lamp is of very simple construction, but can oidy be used with gas. It consists of two vertical iron rods, the anterior Fig. 11. The mode of examining the Ear by aid of sunlight.' of which is about four inches high, and surmounted by a gas-burner whicli tonniiunicates with the vulcanized indiarubber gas-tube. This vertical rod is connected by a horizontal rod, four inches long, with a second vertical rod about three inches high, to the summit of which is fi.xed a circular reflector about four and a half inches in diameter ; and in the centre of which is an orifice for the surgeon to look tlirough, about half an inch in diameter. Attached to the horizontal rod is a ball and socket-joint, and a handle and movable piece by which the lamp may be held in the mouth, and thus l)oth hands left at liberty. Miller 8 lamj), called after its manufacturer, was first suggested by Dr. Chowne ; "but it has undergone great improvements in the hands of its maker. It consists of a wax candle, inclosed in a Palmer's spring tube, about six inches in length, standing upon a foot aljout two and a half inches in diameter and three-quarters of ' In this figure the head of the patient ought to incline more to the right shoulder. THE EXTERNAL MEATUS ITS EXPLORATION. 63 an inch deep, so as to hold the reflector when not m use. For the top there is a cap -which acts as an extinguisher, and also as a de- fence to the candle when carried about. This lamp will, I think, he Fig. 12. Fig. 13. Miller's Lamp, open. Miller's Lamp, closed. found efiicient and economical, not merely in cases of disease of the ear, but in all cases where a lamp is required. In addition to the lamp, specula are necessary for the examination of the ear. Speculum aicris. — Various complicated and somewhat expensive instruments have been invented for the purpose of straightening the outer half of the meatus, for slightly dilating it, and for con- centrating the rays of the sun, or of an artificial light, on the sur- face of the tube and on the membrana tympani. The one in general use previous to the last ten years was the foi'ceps-specuJum: it is made of steel, and consists of two handles or branches crossing each other, but having a strong spring between them ; each of these branches is attached, at the extremity furthest from the handle, to half a metallic funnel, and when the handles are pressed together, the two halves of tlie funnel separate. Is is used by placing the small extremity of the funnel in the outer part of the meatus, and 64 THE DISEASES OFTUE EAR. then opening it so as to dilate tlie tube. The objections to the for- ceps-speculum, and indeed to all modifications of it, consist in its being cumbrous, expensive, and not efficient. Thus this instrument is too heavy to remain in the external meatus without being held ; on account of its weight and size it cannot be used "with delicacy, while a sensitive meatus is liable to be pained by it ; further, it re- quires the exclusive use of one hand, so that it cannot be well em- ployed during the performance of an operation, or the use of ajiplica- tions to the meatus or mcmbrana tympani. Another great oly'ection to the forceps-speculum is, that when the tAvo portions of the funnel are st'()arated in the meatus, two spaces are left between them, through which hairs or portions of epidermis and cerumen often project, and obstruct the passage of light. To remedy some of the above defects, the tubular ear-speculum was invented by Dr. Gruber, of Vienna, and introduced to the notice of English surgeons by Mr. Wilde, in his paper on Otorrhjea, pub- lished in 1844 in the Dublin Journal of 3Iedieal Science. Mr. Wilde describes it as consisting of " a small conical tube of silver, measurinff about an inch and a half in length, five-eifjliths of an inch in width at the greater aperture, and varying from two to four lines in the clear at the small extremity." The interior and exterior of each extremity is polished, and both openings are circular. Two or three sizes are recommended. There can be no doubt that this speculum was a great improvement over any previously suggested ; but upon comparing its shape with that of the tube it is intended to explore, two grave defects are detected. The first is the coniform shape of its small extremity ; for the widest part of the speculum is introduced into the narrowest part of the tube, and its extremity projects into and obstructs that portion of the meatus which it is desirable should be free. With a speculum of this shape it is, secondly, very difficult to explore the whole of the meatus, and it is not sufficiently embraced by the meatus to retain its position without being held. These disadvantages of the conical speculum were ob- served by the late Mr. Avery, who devoted so much time, and did so much to facilitate the exploration of the various mucous canals. He suggested that the narrower portion of the speculum, for about three-quarters of an inch, should be of the same diameter throughout. There remained, however, tlie other very serious defect in the tubu- lar speculum of the circular form of its small extremity. As has been said, the surgeon can readily assure himself of the oval shape THE EXTERNAL MEATUS ITS EXPLORATION. 65 of the outer meatus, and that the anterior and posterior walls of the tube are flat and only slightly concave ; a form that also partially obtains in the bone. It is clear, therefore, that when a circular tube is introduced into this oval-shaped meatus, it may press against the anterior and posterior walls, and yet leave a considerable space above and below it unoccupied. As a rule, therefore, it is impossible by means of this form of instrument to obtain a view of more than a small portion of the meatus arid membrana tympani at the same time ; and should the meatus be very small, the circular tube does not give passage to a suflficient quantity of luminous rays to enable the surface of the membrana tympani to be discerned. Another disadvantage of the circular speculum is, that the pressure of its convex surface against the anterior and posterior walls of the meatus, Fig. 14. A set of Specula for the purpose of examining the External Meatus which are nearly flat, is liable to produce pain, especially where the tube is small. It is therefore evident that the part of the speculum inserted into the meatus should be of an oval shape. This modifica- tion of the tubular ear-speculum Avas suggested by me in a paper in the Lancet, published in August, 1850 ; since which time most of these instruments have, I believe, been made of this shape, and have been found to answer every purpose for which a speculum auris can be required. In order to hold the speculum more firmly, it is desira- ble that the expanded portion should bo somewhat flattened ; and this flattening should be at right angles with that of the smaller extremity, A set of three or four specula should be in possession of the surgeon. It has been suggested that the tubular ear-speculum should be made 5 66 THE DISEASES OF THE EAR. of glass silvered ; but the thickness of the material would, occupy too large a portion of the cavity of tlie meatus. Mode of examination. — After the preliminary investigation has been conducted, the patient being as nearly as possible on a level with the surgeon, the latter, taking the lamp in one hand, sliould feel and inspect the external ear and the orifice of the meatus, Avith- out the use of the speculum. Having done this, a speculum adapted to the size of the meatus is to be taken in hand, and introduced into the orifice of the meatus, care being taken that the long diameter of each coincides. If the speculum enters very easily, and there ap- pears to be room for a larger one, the next size should be selected, and the orifice fully dilated ; for in all cases, the larger the speculum used the greater will be the quantity of luminous rays entering the tube, and the more complete the view of the meatus and membrana tympani. The speculum, having been introduced, is to be pressed slightly backwards, for the reasons I have mentioned, and then, by Fig. 15. The Surgeon examining the External Meatuf: by means of Miller's Lamp and the Tubular Speculum. means of the lamp in the other hand, the rays of light are to be di- rected successively on the several walls of the meatus and on the membrana tympani. The size of the different parts of tlie tube, the THE EXTERNAL MEATUS ITS EXPLORATION. 67 quantity, color, and position of the cerumen, if present, should be noted ; if absent, the state of the part of the tube in which it natu- rally exists, and the degree of vascularity of the dermis lining the inner half of the meatus. A considerable degree of care is required in the examination of the meatus in the infant and child. The total absence of the osseous meatus in the former, and its very limited size in the latter, should always be borne in mind, or the surgeon, when he introduces the speculum, is apt to press upon the membrana tympani. In many cases it is necessary only to open the orifice of the meatus, when the membrana tympani is at once seen Avithout the introduction of the speculum any further. CHAPTER IV. THE EXTERNAL MEATUS {coniinued). OX FOREIGN BODIES AND ACCUMULATIONS OF CERUMEN IN THE MEATUS. FOREIGN BODIES IN THE MEATUS — MODE OF REMOVAL — CASES CERCMINOrS GLANDS — THEIR DISEASES — ACCCMtJLATIONS OF CERUMEN — THEIR CAUSES — TABLE OP TWO HUNDRED CASES IN WHICH THE CERUMEN WAS REMOVED — SYMPTOMS — EFFECTS — TREATMENT — MODE OF REMOVAL — THE SYRINGE AND ITS USE — CASES. FOREIGN BODIES IN THE MBATUS. Foreign bodies are frequently introduced into the outer meatus. Among those which have fallen under my own notice may be named beads, slate-pencil, leaves, a shell, a pea, sealipg-wax, a percussion- cap, a pin, a piece of paper, seeds of grass, tobacco, wool, cotton- wool, human hairs, bacon, lint, camel's-hair pencil, and camel's hair. When a body is put into the meatus by design, it is either done by a child in play, or by an adult for the purpose of medical treatment, or an alleviation of the itching of the tube. "When a patient is sus- pected of having a foreign body in the ear, the first step of the sur- geon is to make a careful inspection of the tube in suidight or with the speculum and the lamp, with the view of ascertaining whether there really is anything present. In a great number of cases, having explored the whole of the meatus, and seen the membrana tympani, he will be able to assure the patient or the friends that no foreign substance is there. For want of this pre-inspection, lives have been destroyed in attempting to extract from the ear imaginary bodies which had never lodged there. Medical men are not generally aware of the impunity with which a foreign substance may continue for a time in the meatus. It is not uncommon to find a mass of hard cerumen in contact with the whole of the meatus and with the outer THE EXTERNAL MEATUS. 69 surface of the membrana tympani, without causing any pain or inflam- mation ; and I have frequently removed other substances, as beads, pebbles, &c., which had been either in contact with the membrana tympani or in its immediate vicinity, Avithout causing any painful irritation. Nor is this remarkable when it is remembered that the meatus and outer surface of the membrana tympani are a continua- tion of the outer skin, and, like it, covered with a layer of epidermis. The meatus and membrana tympani are extremely sensitive when pressed upon by hard or rough substances ; but soft, smooth bodies may be gently pressed against them without exciting pain. Thus the artificial membrana tympani, made of vulcanized india-rubber, is placed against the outer surface of a perforated membrana tympani without producing any unpleasant sensation. When a foreign body has been detected in the external meatus, it should be removed as soon as possible. The syringe and warm water are, as a general rule, quite sufficient to remove all rounded solid bodies. I have succeeded in extracting beads and other hard sub- stances which appeared to be impacted in the meatus, by means of the syringe only, though a good deal of time is occasionally required. It may at times be useful to move the body slightly by means of a probe a little bent downwards, so as to facilitate the passage of the water to the back of it ; for the mode by which the syringe acts, is in forcing the warm water inwards behind the foreign body, and thus gradually expelling the latter outwards. Mr. Wilde and other writers recommend the use of the curette, spatula, or forceps, in the extraction of extraneous substances from the meatus : but I have rarely been obliged to use any of these instruments, and resort to them should be avoided if possible. Dieifenbach, who advocated the use of a curved director, or curette, must have met with cases show- ing the practice to be dangerous ; for he says, " Should violent bleeding supervene, and there be no likelihood of completing the operation at one sitting, cold and afterwards warm applications are to be resorted to, to prevent suppuration." It is also almost impos- sible to pass a curette between the extraneous substance and the meatus without impelling that substance inwards, in which case it is very apt to be pressed /orc?^/?/ against the membrana tympani, and cause inflammation. Cases are sometimes met with in which the most lamentable results have followed attempts at removing foreign bodies by instruments. Death itself has not unfrequently happened ; 70 THE DISEASES OF THE EAR. and -vvliei-o tlie life of the patient has been spared, the car has some- times been destroyed and the ]>o)'tio dura nerve paralyzed. Should a patient apply for relief "who has much inflammation and tumefaction of the meatus, consequent perhaps upon attempts pre- viously made to remove the body by instruments, the best course is to apply leeches and fomentations to subdue the inflammatory symptoms, before attempting the extraction by the syringe. In certain cases the presence of a foreign body in the meatus cives rise to coufrhiu'r, and even to vomitiiij: ; svmptoms ■which seem traceable to irritation of the auricular branch of the pneumo-gastric nerve. A patient under my care, "with a portion of dead bone in the meatus, suffered under a cough, -which no treatment subdued, but -which disappeared as soon as the bone -was removed. In a notice of Professor Romberg's work, in the British and Foreign Medical Hevieic, \o\. XVII, it is stated tliat Arnold met -with a case of chronic vomiting in a child, -which long resisted all medical means, but -which -was cured by removing a bean from each of the child's ears. There are substances of a different character from those already alluded to -which arc not so easily removable by the syringe. These are -wool, cotton--wool, tobacco, leaves, paper, and similar soft mate- rials, -which expand in the tube and perfectly fill it. If the syringe fails to remove these bodies, they can be seized Avith the lever-ring forceps, ^vitll ^v]lie]l they can be easily -witlidra-wn.* Insects some- times enter the meatus, and arc apt to cause more irritation than the presence of solid bodies. If they touch the membrana tympani, they cause extreme sensitiveness of it, and spasmodic contraction of the tensor tympani muscle. The use of the syringe, or, if that be not at hand, the pouring of a little -warm -water into the ear, affords instant relief. Foreign bodies Avhich press upon the outer surface of the membrana tympani are apt to force the chain of bones inwards, and thus press the stapes towards the vestibule, causing the peculiarly distressing symptoms of giddiness and confusion in the head which not unfrequently attend upon an accumulation of cerumen. These cease as soon as the foreign body is extracted. There is little known as to the effect of narcotics introduced into the external auditory meatus : but I have every reason to believe that the narcotic property of a piece of tobacco in the meatus was the cause, in one instance, of very serious cerebral derangement. ' See a description of this instrument in Chapter YI. I THE EXTERNAL MEATUS. 71 It is probable that, in the following case, the foreign body escaped spontaneously. M. S., aged 9, was brought to me by a medical man, in January, 1852. He stated that, on the previous evening, the mother of the child had seen her put a bead into the right ear ; that he himself had seen what he supposed to be the bead, but he had been unable to extract it by the forceps. By means of the lamp the surfaces of the meatus and membrana tympani were seen, and the dermis throughout was much congested, especially near the orifice where the forceps had been applied, but no foreign substance could be de- tected. CASES OF FOREIGN BODIES REMOVED FROM THE EXTERNAL MEATUS. Case I. Slate-pencil in the ear of a cJiild. — J. S., aged 7, Avas brought to me at the St. George's and St. James's Dispensary, on November 28th, 1849, her mother stating that she had pushed a piece of slate-pencil into the right ear. She had not complained of pain, and had slept well. Upon examination, by means of the speculum and lamp, a rough piece of slate-pencil was observed lying on the floor of the meatus, one end being apparently in contact with the membrana tympani, while the other looked towards the orifice of the meatus. It was easily removed by the syringe and warm water, and found to be nearly half an inch long, and a quarter of an inch broad. The membrana tympani was red, the bloodvessels of its dermoid layer being distended. The patient did not complain of pain, and in a few days the membrana tympani was healthy. Case II. A percussion-cap in the ear for fifteen years. — C. E.. aged 26, was admitted at St. Mary's Hospital in November, 1852. She said that lately she had felt somewhat deaf in both ears. Upon examination, a mass, like hardened wax, was observed near the orifice of the left meatus. It Avas removed by the syringe, and proved to be a percussion-cap surrounded by Avax. The patient said that she remembered, when about 11 years of age, she put a cap into her ear, but she believed it had been taken out, and had never thought of it since. The membrana tympani was concave, the Eustachian tube natural, and the power of hearing was nearly gone. Right ear : hearing distance seven inches, membrana tympani dull. concave ; Eustachian tube natural. It appears that the thickening 72 THEDISEASESOFTIIEEAR. of the right incmbrana tynipani had recently caused a dulness of hearing in that ear : the left ear had doubtless been useless for some time ; but so long as the right ear remained perfect, the defect in the left was not observed. Hairs are apt to collect in the meatus ; they either enter in small pieces while the hair is being cut, or those growing at the orifice fall inwards : great iritation is caused by them. Case III. A coUeetion of hairs in the external meatus. — W. S., aged 09, complained of an extremely unpleasant crackling in the right ear whenever he moved the head or ear. It came on two months before seeing me, after bathing in the sea; and he had had a similar attack some years previously, which had subsided sponta- neously. The hearing distance was three inches. A large mass of short liairs was syringed out of the ear ; the symptom of crackling at once disappeared, and the hearing distance became two feet. Another gentleman, from the same cause, was troubled with excessive itching. Fig. 16. Rectangular Forceps. Case IV. A pin iiiipaeted in the rneafus. — A. R., a servant, aged 35, came in great fear and in some pain, complaining that wliile picking the left ear with a pin she had dropped it into the ear, and was unable to remove it. The head of the pin was seen to lie close on the membrana tympani at its lower part, and the point seemed to be inserted in the membranous meatus. The syringe proved ineffec- tual, and I therefore had to remove it with the rectangular forceps, an instrument of great utility wliere the extraneous substance cannot be otherwise removed. On attcni])ting to withdraw the pin, I dis- coverctl that its point was firmly fixed in tlie dermis, and that the only way to extricate it was to seize it by the middle, jiush it gently THE EXTERNAL MEATUS. 73 inwards against the raembrana tympani, and then suddenly draw it out. Cotton-wooL — In one case a portion of cotton-wool had been in the right ear for ten years without producing any other symptom than a feeling of fulness. In the following case, where it rested on the membrana tympani, symptoms similar to those of pressure on the brain were very decided. Case V. Cotton-wool in the meatus. — The Rev. 0. M., aged 55, consulted me in 1840. Since an attack of measles when a child, has had a discharge from the left ear ; and has been accustomed to push a portion of cotton- wool into the meatus. Has lately suffered from giddiness and a sensation of Aveight on the head ; which symp- toms his medical advisers thought were produced by derangement of Fig. 17. The External Meatus greatly dilated by a piece of Cotton-wool ; the latter is seen below, and to the left. the Stomach, as during attacks of dyspepsia he was decidedly worse. Upon examination a large quantity of cotton-wool Avas observed in the meatus in contact Avith the membrana tympani : it had evidently been pushed in by other portions which had been thrust upon it. The cotton was removed by means of the syringe, and was found to have closed an orifice in the membrana tympani. After the removal of the cotton, the attacks of giddiness wholly subsided. In a dissection, of which a drawing is subjoined, I found a piece of cotton-wool in the meatus, where it had probably remained for many years; and it had so largely dilated the bony meatus, that the index finger could be passed in as far as the membrana tympani. Case VI. A shell in the meatus ; removal by instruments ; para- 74 THE DISEASES OF THE EAR. lysis of the jjortio dura nerve. — Miss A., aged 14, consulted me, in May, 1853, on account of complete deafness of the right ear and paralysis of the right side of tlie face. Iler father stated that eight years previously she had, in play, put a small shell into the ear ; that the surgeon, in endeavoring to remove it, forced it deeper into the ear, breaking the shell, and causing intense pain. After its re- moval there was much discharge from the ear, and in a few days the muscles of the right side of the face lost their power, Avhich they have not regained. Upon examination there was no vestige of the memhrana tympani ; the mucous membrane of the tympanum was very thick and red, and there was not the slightest power of hearing. Case VII. Tobacco in the meatus; i^ain and numbness in the head; ^mrtial stupefaction, inability to walk straight. — M. B. S., aged 50, applied for relief in 1843. He stated that for four months he has had pain and a sensation of numbness in the right side of the head, which feelinn;s are much ago-ravated at times. He also com- plains of giddiness, and sometimes reels across a room ; at otliers he is obliged to sit down, feeling quite oppressed and stupefied. He has also suffered from indigestion. Upon consulting a medical man, he was treated by cupping, purgatives, &c., but without relief. Upon examination of the right external meatus, a considerable quantity of black matter was seen, which was easily removed, and was found to consist of tobacco in a moist state, mixed Avith cerumen and wool. The next day the head-symptoms were much diminished ; in a few days they wholly disappeared, and the patient remained free from them. Tiie tobacco had been introduced into the meatus a short time before the attack, on account of toothache. The mass was soft, and so loosely packed that it appears probable the symptoms were caused by the narcotic principles of the tobacco, rather than by its pressure on the membrana tympani. In cases of pressure, too, the symptoms disappear at once on the removal of the cause ; whereas, in the present instance, they subsided slowly. THE CERUMINOUS GLANDS AND THEIR DISEASES. The ceruminous glands surround the outer half of the membra- nous meatus, Avith the exception of the portion situated within a line or two of the orifice. They are contained in the cellular tissue be- neath the dermis, on the surface of which the ducts open. Kolliker THE EXTERNAL MEATUS. 75 has recently shown them to bo modifications of the sudoriferous and not of the sebaceous glands, as was previously supposed. The ceru- men secreted by these glands forms, in the perfectly healthy ear, a band about half an inch in length, and half a line thick. This band should be of a consistence just sufficient to enable it to retain its position, at the same time that it can collect the small particles of dust, &c., which float in the atmosphere, and prevent their accumu- lation on the surface, or in the vicinity of the membrana tympani. Two other functions ascribed to the cerumen are, that by its bitter taste it prevents the ingress of insects ; and that in some peculiar manner it assists the poAver of hearing. Its principal use is unques- tionably to arrest and collect the particles of dust. Its bitterness may possibly deter the entrance of insects ; but the idea that it me- chanically assists in collecting or conducting the sonorous vibrations to the labyrinth, or that it is of any use, in fact, in the actual pro- cess of hearing, is, in my opinion, quite erroneous. No doubt its absence is very frequently accompanied by a diminution of the hear- ing power ; but this absence appears rather to result from the sym- pathy which exists between these glands and the deeper structures of the ear. Very often, when these return to their normal state, the ceruminous glands again pour out a healthy secretion. The most convincing proof that the cerumen does not mechanically assist in the function of hearing is, that in many cases, when the ceruminous glands alone are affected, and their secretion consequently arrested, no diminution in the heai'ing power can be detected even by the use of the most delicate tests ; and cases must frequently occur to medi- cal men, where there has been a long-continued discharge from the surface of the dermis, no cerumen being secreted, without perceptible diminution of the hearing power. It is also well known that the entire removal of the ceruminous secretion does not impair the hear- ing power ; and in no case of deafness has it been shown that the introduction of cerumen or of any substance to supply its place, or even the promotion of its healthy secretion under the influence of stimulants, has in the least degree improved the hearing. Indeed, if the peculiar properties of soft cerumen be considered, it must be manifest that its function would be rather to absorb superabundant sonorous undulations than to increase their intensity. The natural method whereby the cerumen when it has performed its duties is expelled from the ear, is the action upon the external meatus of the condyloid process of the lower jaw, during the movement of masti- 76 THE DISEASES OF THE EAR. cation .iiul articulation. By these movements, the cerumen is brought quitf to the orifice of the meatus, whence it either falls out in small particles, or is removed by the towel. Diseases of the Cerumhious Glands. — The ceruminous glands sometimes pour out a too abundant secretion, which is either of a light brown color and softer than natural, or hard and dark colored ; it may also be entirely absent. When soft and semi-liquid, it is generally found in young patients having a tendency to glandular enlargements, and in whom the dermis of the meatus is hypertro- \)]\\vt\ ; thus, without any accumulation beyond that which adheres to tlie walls of the meatus, the cavity is nearly filled with cerumen. It is, however, generally found in a state harder than natural ; and this condition, by preventing its free escape from the ear, gives rise to that very common affection, accumulation of cerumen in the ex- ternal meatus. CoUectiuns of Cerumen. — Cerumen accumulates in the external meatus from two different causes : one, a primary affection of the ceruminous glands ; the other, a secondary and sympathetic derange- ment of the deeper-seated cavities. Thus, while in a large number of cases the removal of the accumulated cerumen is productive of im- mediate relief to the deafness ; in others, the hearing is only par- tially or not at all benefited by the operation. In order to ascertain the ninuerical relation between the cases of accumulation that are cured, and those that are only relieved, by the use of the syringe, I have arranged in a tabular form the results of one hundred consecu- tive cases that have occurred in my private practice. THE EXTERNAL MEATUS. 77 TABLE SHOWING THE EFFECT ON THE POWER OF HEARING OF THE RE- MOVAL OF AN ACCUMULATION OF CERUMEN IN ONE HUNDRED CASES J THE NORMAL DISTANCE OF TESTING-WATCH BEING THREE FEET. HEARING DISTANCE BEFOllE HEARING DISTANCE AFTER O REMOVAL. REMOVAL. Right Ear. Left Ear. Right Ear. Left Ear. 22 1 inch 8 inches 18 inches 18 inches 22 normal : no cerumen half an inch normal normal 32 7 inches crack of nails 12 inches 7 inches 70 contact contact contact contact 33 half an inch half an inch normal normal 35 2 feet half an inch normal normal 45 contact half an inch 2 inches 2 inches 15 half an inch 3 inches normal normal 44 normal : no cerumen half an inch normal normal 59 1 inch : no cerumen crack of nails 1 inch crack of nails 25 crack of nails 3 in. : no cerumen 1 inch 3 inches 18 4 inches half an inch normal normal 29 5 inches normal : no cerumen normal normal 8 contact contact 3 inches contact U half an inch half an inch half an inch half an inch 49 G inches 6 inches 6 inches 6 inches 53 crack of nails 2 in.: no cerumen 4 inches 2 inches 28 half an inch normal: no cerumen normal normal 26 1 inch half an inch 8 inches 7 inches 26 half an inch 2 inches normal 12 inches 49 9 inches 1 inch 9 inches 1 inch 19 7 inches 1 inch 7 inches 24 inches 32 quarter of an inch half an inch normal normal 53 normal half an inch normal normal 30 half an inch 10 inches 6 inches normal — 2 inches I2 inch 2 inches half an inch 41 18 inches 5 inches 18 inches 8 inches 65 contact contact 2 inches 2 inches 27 pressure pressure half an inch 3 inches 44 4 inches pressure 6 inches 3 inches 25 24 inches 1 inch normal 3 inches 40 pressure normal normal normal 65 crack of nails crack of nails 2 inches contact 27 12 inches contact normal normal 27 18 in.: no cerumen pressure 18 inches 18 inches 70 pressure pressure 1 inch 1 inch 56 normal pressure normal 7 inches 2 inches 2 feet normal normal 20 2 inches 2 in.: no cerumen 2 inches 2 inches 53 24 in.: no cerumen contact 24 inches 12 inches 38 contact half an inch normal normal 7 2 inches normal : no cerumen 24 inches normal 14 2 inches 5 inches 24 inches 24 inches 29 2 inches 6 inches normal 12 inches 40 4 inches pressure 8 inches 5 inches 14 contact normal: no cerumen 6 inches normal 35 7 inches half an inch normal normal 22 2 inches contact 24 inches normal 78 THE DISEASES OF TUE EAR. BEARING DISTANCE BEFORE UEARINO DISTANCE AFTER H REMOVAL. REMOVAL. Rigla Ear. Left Ear. RigJu ESt. Left Ear. 45 IG inches 3 inches 24 inches 8 inches 19 normal : no cerumen contact normal normal 28 normal : no cerumen pressure normal normal — normal : no cerumen half an inch normal normal 46 quarter of an inch pressure half an inch half an inch 23 4 inches 5 inches normal normal 44 pressure pressure normal normal 25 normal : no cerumen 1 inch normal normal 14 2 inches 2 inches normal normal 60 1 inch 1 inch 9 inches 9 inches 27 normal half an inch normal half an inch 50 18 inches pressure 18 inches 24 inches 20 2 inches 4 inches normal normal 11 2 inches half an inch 8 inches 8 inches 50 2 inches normal normal normal 45 half an inch half an inch 1 inch 1 inch 5 crack of nails: no cerumen 2 inches crack of nails 4 inches 35 10 inches 2 inches normal normal 28 1 inch 24 inches 24 inches 24 inches 41 normal : no cerumen contact normal 24 inches 14 12 in.: no cerumen 2 inches 12 inches 24 inches 24 pressure pressure normal 2 inches 60 1 inch contact 1 inch contact 34 normal: no cerumen 24 inches normal normal 19 2 inches 1 inch 24 inches 24 inches 61 2 inches 2 inches 3 inches 3 inches 65 crack of nails crack of nails crack of nails qrack of nails 24 contact 2 inches normal normal 40 normal: no cerumen contact normal 8 inches 60 contact crack of nails contact crack of nails 56 quite deaf: no ceru. contact quite deaf 6 inches 21 normal : no cerumen 6 inches normal normal 40 6 in.: no cerumen 4 inches 6 inches 12 inches 51 normal: no cerumen contact normal 3 inches 50 G inches 6 inches normal normal 55 crack of nails contact: no cerumen contact contact 41 12 in.: no cerumen contact 12 inches 5 inches 27 normal: no cerumen half an inch normal 4 inches 50 normal: no cerumen contact normal 1 inch 46 2 inches half an inch 24 inches G inches 35 normal: no cerumen pressure .normal 12 inches 45 3 inches 3 inches 3 inches 3 inches 74 crack of nails 2 inches 3 inches 6 inches 49 half an inch half an inch 4 inches 4 inches 57 half an inch 2 inches 1 inch 3 inches 36 crack of nails crack of nails 1 inch 1 inch 39 pressure crack of nails normal normal 39 4 inches contact normal 14 inches 25 2 inches normal : no cerumen normal normal 52 8 inches 1 inch 8 inches 2 inches 54 normal : no cerumen contact normal 6 inches 11 contact contact 12 inches 12 inches THE EXTERNAL MEATUS. 79 An analysis of the foregoing 100 cases shows the following to be the result of the examination of the 200 ears : — Ears restored to a normal condition, ....... 60 Ears in which the hearing power was greatly improved, . . . .43 Ears in which the hearing power was only slightly improved, . . .35 Ears in which tlie hearing power was the same after as before the removal of the cerumen, .......... 27 Ears in which there was no wax, and in which tlie hearing power was normal, the opposite ear being affected, ...... 24 Ears in which there was no wax ; but in which the hearing power was not perfect, the opposite ear being affected, ...... 11 200 It thus appears that of the 165 ears from which cerumen was re- moved, only GO were cured; that, including the 43 cases which were much improved, there were 103 cases of great amelioration, while there were 62 ears that were either but slightly or not at all im- proved. Thus, out of the 165 ears from which a collection of ceru- men was removed, there were 105 in which there was some other disease, the restoration of the hearing not being perfect. The pre- sence of cerumen in the external meatus may be symjjtomatic of several affections, as obstruction of the Eustachian tubes, or thick- ened condition of the tympanic mucous membrane, debility of the auditory nerve, anchylosis of the stapes, &c. ; it is therefore impor- tant that every case should be carefully examined after a collection of this kind has been removed ; because, if the hearing power be not wholly restored, some other disease is present which requires at- tention. The causes producing accumulation of cerumen in cases not com- plicated with other diseases, are, — a narrow calibre of the meatus ; the application of cold ; the admixture of dust with the cerumen ; and, not unfrequently, the practice of pushing into the ear the point of a towel, whereby the cerumen is pressed into a mass toAvards the membrana tympani. The symptoms of an accumulation of cerumen are : sudden deaf- ness, often following a cold by which the dermis is tumefied ; bath- ing or the introduction of water into the ear. This deafness is often better in the morning ; is increased by the movements of the jaw during mastication ; and often disappears as suddenly as it came, with a cracking sound in the ear. The cause of the sudden appearance and disappearance of the deafness is the movement of 80 THEDISEASESOFTHEEAR. the mass of cerumen : when it is so pUiccd as to allow sonorous vi- brations to pass between it and the wall of the meatus, the hearing returns ; but when it again conies in contact with the meatus, the deafness recurs. Oftentimes a feeling of fulness in the ear is com- plained of; not unfrequently there is singing and giddiness, and sometimes considerable pain. The symptoms of a collection of cerumen in the meatus vary according to the nature and position of the mass. Sometimes the whole of the meatus is distended by cerumen, the inner end of which lies in contact with the outer surface of the membrana tympani, of which it often forms a cast. In these cases, there is often giddiness arising from the pressure on the chain of ossicles. The symptoms of pressure on the brain are familiar to most surgeons ; but it is not Fig. 18. Cerumen in contact with the outer surface of the Membranii Tympani. generally known that pressure on the contents of the labyrinth pro- duces somewhat analogous symptoms. A mass of cerumen may force inwards the membrana tympani and the chain of bones, until the base of the stapes is pressed against the contents of the vestibule. In some cases of this nature, constant attacks of giddiness occur ; in others, there is a confusion of ideas and an inability to walk straight ; and in a third class, there is a feeling of weight and pres- sure on the head. These symptoms are often combatted by the use of counter-irritants antl depletion ; but the only proper remedy for them is the removal of the accumulation. In certain cases there is a large mass in the outer half or two- thirds of the tubes, while the portion near the membrana tympani is empty ; in others there is only a small quantity, which adheres to the outer surface of the membrana, and gives rise to great irri- THE EXTERNAL MEATUS. 81 tation, and irregular action of the tensor tympani muscle. When the mass is very hard, it is liable to cause inflammation of the der- moid meatus. A collection of cerumen may remain in the ear for many years, and the ears of the patient may have been frequently syringed without the nature of the affection being detected. Those accustomed to pay attention to cases of deafness will, however, generally be able to state when cerumen is present, even without any examination. I have frequently diagnosed the disease from Fic. 19. Meatus greatly dilated by cerumen. the written account of a medical man ; and a repetition of the syringing (which had previously been practised), but with increased vigor, has entirely removed the deafness. An examination with Fig. 20. Anterior wall of the Osseous Meatus partly absorbed, following the pressure of an accumulation of cerumen. the speculum and a strong light should, however, always be made before adopting any treatment. The prolonged presence of hardened cerumen in the external 6 »2 THE DISEASES OF THE EAR. meatus is sometimes productive of injury to the walls of the meatus and to the memhrana tympani. In my museum are several speci- mens in which the osseous meatus has been much dilated ; others in which the bone has been absorbed in parts ; and in one instance a portion of wax was imbedded in the mastoid cells, having passed through an orifice in the attenuated posterior wall of tlie meatus. In another instance, wliere the cerumen, by its pressure, had caused an ulcerated orifice in the membrana tympani, a portion of it had found its way into the cavity of the tympanum. Fig. 21. Cerumen projecting through the Membrana i _ _ mto the Tympanic Cavity. The treatment of cases in which there is an accumulation of ceru- men of course consists in its removal. The best, and indeed the only judicious mode of effecting this, is by the use of the syringe, which will thoroughly clear out even the hardest masses. The use of other instruments, as the scoop, has been suggested ; but I have rarely known them to have been used without the production of pain, inflammation, and often of discharge from the dermis. No doubt the ordinary small syringe is not powerful enough to remove a hard- ened mass ; but the one I usually employ, and which is valuable for many other purposes, holds three ounces and a half, and is furnished with two rings, so that it can be held in the right hand, and leave the left at liberty to hold the ear of the patient. The nozzle of the syringe consists of a metallic tube of very small size, wliich sliould Ite made to takeoff until the water has been drawn in through the large aperture, and tlien be again fi.xed on. By doing this, air is kept out of the syringe and much time is saved, as it is not easy to fill a large-sized syringe through a small aj)erture. The point of the nozzle should be somewhat larger tlian the body of THE EXTERNAL MEATUS. 83 an ordinary probe, so that the water may be injected Avitli sufficient force, and its return at the orifice be unimpeded. The ear of the patient should be brought opposite to a window, and tlie point of the Fig. 22. Syringe and Nozzle. syringe should be placed at th^ posterior part of the orifice of the meatus, or the stream is liable to strike against the anterior wall of the tube. Whenever the syringe is used, the ear should be drawn backwards so as to straighten the tube ; and if this cannot be ef- fected, on account of the left hand of the surgeon being otherwise engaged, the posterior wall of the meatus may be pressed back- wards by the point of the syringe. Warm water alone is generally sufiicient, without the use of any solvent. It should be quite clear ; and it is always desirable to have two vessels ; one for the water before it is used, and the other to receive it when returning from the ear. If a glass vessel be used for the latter purpose, the condi- tion of the water, and consequently of the ear, is more readily as- certained. The use of an ear-spout is very serviceable during the process of syringing. It consists of a spring to pass over the head, 84 THE DISEASES OF THE EAR. at one end of which is a funnel to fit uiKlcr the ear, down which the water can run into the basin. In many cases, when the collection of wax is not very hard, the Fig. 23. Ear-spout, fitted on the lieml. injection of one or two syringes full of warm water is sufficient to dislodge the mass ; in others, a much longer time is required, and when the wax has been very hard, I have sometimes injected warm water for twenty minutes or half an hour Avithout removing any particles, or even causing the water to be clouded. At times, it is well to let the wax become softened by the water before using the syringe again ; and where the cerumen is unusually hard, or the meatus so tender that the syringing causes much pain, it is desirable to order a weak alkaline solution to be dropped into the ear in the intervals. As it is not desirable to proceed with the syringe when there is no wax left, the meatus should be frequently inspected to ascertain the progress made, as the deposit frequently comes away slowly in small pieces ; the last portion, however, is usually large, and is often a cast of the membrana tympani. After the extraction of the cerumen, a piece of cotton-wool may be worn for a day or two. CASES OF ACCUMULATION OF CERUMEN IN THE MEATUS EXTERNUS. Case I. — Mrs, R., aged 38, consulted me in July, 18r)4, on account of great dulness of hearing. She stated tliat. without any previous THE EXTERNAL MEATUS. 85 symptoms, ten months previously she had become suddenly deaf, first in one ear and then in the other. After being deaf for a month, there was a crack in each ear, and she regained her hearing, which had remained perfect until Avithin a few days, when, during a severe cold, slie again became deaf. Upon examination, I found the meatus of each ear full of dark cerumen ; the hearing distance Avas only half an inch, and the patient required to be spoken to loudly within a yard. Upon removing the cerumen the hearing was perfectly re- stored. Case II. 3Iass of cerumen extremely hard and very difficult to remove. — Lord D., aged between 50 and 60, consulted me, in April, 1851, on account of deafness in the right ear, accompanied by a sensation of fulness in that organ. A large mass of cerumen Avas detected in the meatus, Avhich Avas not at all affected by syringing for half an hour. A solution of carbonate of soda in Avater (5j @ Sj) Avas ordered to be dropped into the ear for some days ; but the mass was scarcely at all softened. The application of the solution Avas therefore continued, and it Avas only after several Aveeks that the cerumen was dissoh'ed sufiiciently to be remoA^ed Avith ease. Case III. Accumulation of cerumen attetided witJi pain and in- flammation of the dermis. — Miss H., aged 30, consulted me in May, 1853, on account of a shooting pain in the right ear which she had experienced, Avith scarcely any intermission, during a fortnight. She was not aAvare that the hearing poAver Avas at all diminished. On examination, each meatus Avas found full of cerumen, the hear- ing distance of the right ear being half an inch ; that of the left, ten inches. The cerumen Avas removed from each ear ; and that in the right was exceedingly hard, requiring frequent syringing. The hearing distance of the right ear rose to six inches ; that of the left became natural. The surface of the right meatus Avas red, and it Avas SAVollen. The pain ceased, and the symptoms of inflammation disappeared, after the cerumen Avas removed. Case IV. A mass of cei'umeii producing inflammation of the der- moid layer of the membrana tympani. — J. R. M., aged 55, a surgeon, complained, in 1849, of pain in the right ear, Avith much deafness. The pain Avas paroxysmal ; A^ery acute ; and Avas increased during the act of SAvallowing. The meatus Avas found distended Avith cerumen, the removal of Avhich gave immediate relief to both pain and deafness. The upper half of the dermoid layer of the mem- 86 THE DISEASES OF THE EAR. bnuia tynipaiii, against whicli the mass of cerumen had evidently pressed, was red and much swollen ; the lower half Avas healthy. Case V. An accumulation of cerumen causing neuralgic pains in the face. — G. W. II., Esq., applied to me, in May, 1853, on account of a dulness of hearing in the right ear, accompanied by slight pain in the ear, and a good deal of pain over the right side of the face. This fiicial pain came on at times very suddenly, was very acute, and then disappeared : it had lasted for eight or nine days. A larfje accumulation of cerumen was found to fill the right ear : and when removed by the syringe, the dulness of hearing, the pain in the car and in the face, entirely disappeared. Case VI. An accumulation of cerumen causing 2)itlsation in the ear. — W. E., Esq., aged 53, consulted me, in October, 1851, on ac- count of a pulsation in the right ear whenever he reclines, but which ceases directly he assumes an upright position. He also complained of occasional singing in both ears. For these symptoms he had for some time been under medical treatment, but it had not succeeded in diminishing them. A mass of cerumen was found filling each ear, the removal of which improved the hearing greatly, and en- tirely removed the pulsation. Case VII. A collection of cerumen in the external meatus ; giddi- ness and other sgmiytoms of cerebral irritation cured at once by the use of the syringe. — L. S. M., Esq., aged 43, consulted me in No- vember, 1845. He stated that, five or six years previously, he had an attack of deafness in the left ear, attended with a considerable amount of singing noise ; since that time he has occasionally felt deaf in the morning, but has usually recovered his hearing during the day, and at times, after blowing his nose, he has been deaf for a short time. Eleven months ago, after going into the open air from a warm room, a singing suddenly came on in the right ear, and has remained ever since. Latel}' he has had a sensation of weight at the top of the head, and fre(|uc'nt attacks of giddiness, which have caused him great alarm. AVhilc walking in the street, he has ob- served himself noAv and then to make "a lurch." Upon inspecting the ears, each meatus was found to be nearly full of hardened ceru- men ; which was carefully removed by means of the syringe. The symptoms immediately disappeared, and he had no recurrence of them. Another patient, an artist, who suffered in the same way, was so giddy that he was obliged to lean on the railings, and rest, on his way to my house. He was also unable to discern the features THE EXTERNAL MEATUS. 87 of his "sitter" for more than a minute at a time, and had the greatest difficulty in writing an ordinary note. He likewise was cured at once by the removal of cerumen from each ear. A third patient was by the same means cured of a constant pain and numb- ness in the head : in a fourth, the pain had extended down the back. The following; case is also interestino- : Case VIII. GonfiLsion in the head, inahility to walk straight, caused hy a collection of cerumen. — Mrs. R., aged 45, consulted me in April, 1845. She stated that, four months previously, she first began to experience noises in the ears, which were followed by a great amount of deafness. These symptoms lasted seven weeks, and then disappeared for three weeks, at the expiration of which time they came on again, accompanied by a sense of confusion in the head. This, at times, was so bad, that not unfrequently, for a few seconds, she could not tell Avhere she was. She has at times been so giddy, that she has reeled and fallen in the streets ; and, at other times, she has not been able to retain her hold of things, so that they have fallen from her hands. On examination, a large compact mass of cerumen was found in each ear ; which, after some syringing, was got rid of ; and the operation was followed by the entire disappearance of all the symptoms. In some cases, the hard mass of cerumen has pressed against the outer surface of the membrana tympani, with sufficient force to cause inflammation of its substance, and of the mucous membrane of the tympanum. When this has been the case, the application of leeches has been required before the head-symptoms entirely disappeared : in other instances, they have only gradually subsided, though, as a general rule, they disappear with the removal of the cerumen. CHAPTER V. THE EXTERNAL MEATUS {con(inued). THE DERMIS AND ITS DISEASES. 1. ACUTE INFLAUMATION : — a, ACUTE INFLAMMATION CONFIXED TO THE DERMIS TREAT- MENT — CASES, b, ACUTE INFLAMMATION EXTENDING TO THE BRAIN AND ITS MEMBRANES — TREATMENT — CASES. 2. CHRONIC INFLAMMATION : — a, CHRONIC INFLAMMATION, WITH UVPEUTROruV AND ACCUMULATION OF EPIDERMIS TREATMENT CASES. I), CHRONIC CATARRHAL INFLAMMATION — TREATMENT — CASES. C, CHRONIC CATARRHAL INFLAMMATION EX- TENDING TO THE BONE AND TO THE BRAIN — TREATMENT — CASES. d, ULCERATION. The diseases to whicli the dermis of the external meatus is subject are : — I. Acute Inflammation, ending in resolution, discharge of scrum, mucus or pus, or in ulceration. II. Chronic Inflammation, Avith or -without discharge, polypoid growths, or caries of the bone. I. Acute Inflammation of the Dermis. This is one of the diseases hitherto comprised under the term otitis. The external meatus is very sensitive, especially towards the middle. This sensibility is due to the dermis, which is abun- dantly supplied with nerves and bloodvessels, and is covered by a delicate layer of epidermis. This membrane is liable to inflammation from many causes, such as the introduction of foreign bodies or acrid drops into the meatus ; an accumulation of cerumen ; the application of cold or of heat, especially when arising from sudden changes of temperature in the weather ; or any debilitating illness. The sijmptomH of this affection, at its connnencement, are a feel- ing of fulness, stiffness, and uneasiness in the meatus, which is in- THE EXTERNAL MEATUS. 89 creased wlien the ear is pressed upon, or Avlicn the outer ear is moved by its muscles. This sensation is followed by pain, often very acute, although not so distressing as in severe inflammation of the mucous membrane of the tympanum : throbbing and singing often accom- pany the pain, and there is sometimes a diminution of the power of hearing. The latter symptoms arc probably due to congestion of the middle and internal cars. With these symptoms there is gene- rally a quick pulse, feverishness, and restlessness ; and the pain sometimes extends over the side of the head. On examination in the early stages, the dermoid meatus is seen to be red, its blood- vessels being apparent through the epidermis. This redness some- times extends to the dermoid layer of the membrana tympani, the vessels in the circumference of which become enlarged. Should the affection advance, the dermis becomes tumefied, so as to diminish the calibre of the meatus one-third or one-half, and the pain increases. In some cases, these symptoms subside without the formation of matter ; in others, a copious secretion suddenly takes place, and is followed by such immediate relief that the patient thinks an abscess has burst. Examination, however, reveals the real condition of the meatus. The discharge filling the meatus having been carefully removed by the syringe, the surface of the tumefied meatus is seen to be of a deep red color, wholly denuded of epidermis, and in its place secreting a mucous fluid. In the severe forms of this inflam- matory action, this secretion consists of mucus, which comes away from the ear as a large mass of viscid white matter, somewhat analogous to that secreted by the mucous membrane of the tympanum in cases of catarrh ; the difference being, that in the case of mucous from the tympanum, the circumference of the mass is more fila- mentous, the color not so white, and the substance less consistent. After this discharge has continued for some days, it loses its viscidity, and becomes milky, remaining so as long as the affection continues to be chronic. When the inflammation is not very severe, the character of the secretion is always milky, not mucous. There are cases in which the secretion is thin, and nearly as transparent as sermn ; at times it is tinged with blood. The quantity of this serous secretion astonishes both patient and medical man, I have never had the opportunity of collecting the secretion, so as to be able to form a correct estimate of the quantity effused in twenty-four hours ; but, judging from the saturation of handkerchiefs, linen, and pillows, it must amount to several ounces. The source of this large quantity 90 TIIEDISEASESOFTHEEAR. of secretion is the bloodvessels of the dermoid meatus, -wliieli are extremely numerous, and very large. Some ])atit'iits are subject to frequent attacks of acute inflamma- tion of the meatus, but in them tlie symptoms are not very severe ; in others, however, the inflammation extends to the bone, and thence to the membranes of the brain. It is not uncommon to see patients in whom there are some symptoms of cerebral irritation, though not of a serious character; -while, in other instances, they are so for- midable as to destroy life. These cases will hereafter be more fully described. Acute inflammation of the dermoid meatus sometimes occurs from injury, but it usually subsides under the use of leeches and fomen- tations. Tlie treatment of acute inflammation of the dermoid meatus con- sists, in the milder cases, of the application of evaporating lotions, or of hot fomentations and poultices ; in the more severe, leeches should be applied to the margin of the orifice of the meatus, so as to remove the blood directly from the congested vessels ; and the meatus itself should be syringed with hot water, the head being slightly raised. The patient should be kept in bed, perfectly free from all noise, and small doses of opium may be administered. After the disappearance of the pain, the ear is to be washed out thoroughly with warm water, three or four times, or even oftener, daily; so as, in the first place, to insure the removal of the whole of the dis- charge, which is apt to cause irritation, and, in the second place, to act as a warm bath to the inflamed membrane. Unless there is con- stitutional del)i]ity, or the ear has been weakened by previous dis- ease, the discliarge usually ceases in the course of a few days ; the epidermis is again naturalh^ secreted ; and the power of hearing re- turns. Cases of acute inflammation of the dermis depending upon constitutional causes, and usually following nervous excitement, re- quire to be treated by tonics in addition to the local applications. In some cases, however, foundation is laid for chronic catarrhal in- flammation of the dermis, of which I shall presently speak. CASES. Case I. Aciifc injlammation of the dermoid vwatus, arhing from cold. — M. F., Esq., aged 26, a medical man, consulted me in January, THE EXTERNAL MEATUS. 91 1853, on account of great pain in each ear. He said that fourteen days previously, after being wet through, he had an attack of violent pain in both ears, — but especially in the left : after twenty-four hours' pain, discharge appeared and relief ensued. The day before consulting me, during a journey, pain Avas again felt in each ear, but more particularly in the right : at times the pain was greatly aggravated. On examination^ the dermis of each meatus was seen to be very red and SAVollen ; the epidermis was absent, but there was no discharge. The hearing distance of each ear was eighteen inches. An evaporating lotion Avas applied on cotton-wool, and the affection subsided. Case II. Acute inflammation of the dermis; cojnous secretion of mucus. — Miss M., aged 17, tall, and rather delicate, consulted me, December 20, 1853, on account of pain in the right ear, accompanied with discharge. History. — Ten days previously she felt a slight pain in the ear, which gradually increased so as to interfere with her rest at night. This continued for eight days, though better at times. Two days previous to seeing me, a discharge appeared from the ear, and has continued. On examination, the meatus was seen to be filled with discharge, which, when removed by the syringe, was found to consist of a large white mass of mucus, about the size of an ordinary horse-bean, and of scales of epidermis. The membranous meatus was much tume- fied, its surface being red ; the dermoid layer of the membrana tym- pani was also red and swollen. The hearing distance was only eight inches. Treatment. — Two leeches were applied to the orifice of the meatus, which was syringed out with warm water twice daily. The pain gradually subsided, and in six days the discharge had disappeared. Case III. Acute inflammation of the dermis; great deafness, and copious secretion of serum. — A. H. H., Esq., aged 38, of a weakly constitution, sent for me in January, 1854. History. — For three weeks he had been suffering from an attack of inflammation of the lungs, and four days previously, when becom- ing convalescent, was seized in the night with a violent pain in the left ear. This, in spite of treatment, lasted for about twelve hours, when a sudden burst of discharge took place from the ear, which much diminished the pain. "When seen by me on the fourth day after the discharge had appeared, there was still great sensitiveness 92 T 11 E D I S E A S E S F T II E E A R. of tlic meatus, and so great an amount of deafness, that the watch Avas not heard even when in contact with the ear. On examination, the dermis was found swollen and red, and the dermoid layer of the membrana tympani in the same state. So copious was the secretion of serum, that in half an liour a white handkerchief was perfectly saturated with it. Great fear was felt lest the car should have been seriously injured by the inflammation ; but finding that the mem- brana tympani stood out naturally, and feeling that congestion of the tympanic mucous membrane Avas quite suflfiicient to produce the deafness, hopes were held out that the hearing would return as soon as the congestion subsided. A leech was ordered to be applied to the margin of the orifice every second day : the meatus was syringed out with warm water twice daily, and slight vesication was used at the back of the ear. In the course of three days the discharge began to subside, the pain ceased, and at the end of ten days the hearing was restored. Case IV. Frequent attacks of inflammation of the dermis; hear- ing power natural. — Miss C, aged 28, consulted me on March 7th, 1854. History. — During two years has been subject to attacks of pain in each ear, followed by discharge, after which there has been an intolerable itching. Three months ago, she suffered from one of these attacks of pain, since which she has had a constant irritation. On examination, the dermis lining each meatus was observed to be red and swollen. The hearing distance of each ear was natural. By applying leeches to the margin of the orifice of the meatus the irritating symptoms disappeared, and the recurrence of the attacks of inflammation was prevented. ACUTE INFLAMMATION OF THE DERMOID MEATUS EXTENDING TO THE BRAIN. Anatomical observations. — The bloodvessels ramifying through the membranous meatus are directly continuous with those entering and supplying the osseous meatus ; the intimate connection between the dermis of the meatus and the bone is therefore very obvious. The relations of the osseous walls of the external meatus to the cavity of the cranium are deserving attention. In the adult, it will be found that the upper wall of the meatus consists of a solid lamina of bone, varying from a line to two lines in thickness, which THE EXTERNAL MEATUS. 93 separates the cavity of the meatus from that occupied by the middle lobe of the cerebrum. In some cases, a prolongation of the tym- panic cavity is found extending into the substance of the upper wall of the meatus. In the child, these relations differ remarkably from those just detailed. At birth, and for the first year subsequently, the only rudiment of the osseous external meatus is the superficial depression situated in the middle of the outer and lower part of the pars squamosa, immediately posterior to the root of the zygomatic process. This depression, to which the name "fossa auditoria" may be appropriately applied, has the rudiments of the mastoid process posterior to it ; its surface is smoother, and its substance denser, it also contains fewer foramina for the transmission of bloodvessels, than the surrounding bone. At the period of birth, the portion of bone forming the fossa is not more than half or three-quarters of a line thick, and the membranous meatus is attached to the outer, the dura mater of the middle cerebral cavity to the inner surface. Its structure is far from being compact or dense, and in its substance the bloodvessels from the meatus communicate with those of the dura mater. As the bone approaches maturity, the fossa assumes an oblique position, and forms the upper wall of the external auditory meatus, while it is separated from the cavity of the middle cerebral fossa by a dense layer of bone, into which cells communicating with the tym- panic cavity are not unfrcquently prolonged. In the adult, the fossa auditoria has nearly lost its oblique direction, and become a horizontal lamina of bone. From the foregoing remarks, it will be evident that disease of the membranous meatus externus is liable to extend to the outer surface of the bone, and thence to the interior. In the only case of fatal chronic disease which has fallen under my notice, the disease ad- vanced, posteriorly, to the lateral sinus. Acute injlammation of the dermoid meatus may arise from the application of cold to the ear, or from the irritation of a foreign body : but neither cause is usually sufficient to produce extensive inflammation of the brain or its membranes, unless considerable con- stitutional irritation coexists. For the particulars of the following case I am indebted to Dr. Nairne, who gave me the opportunity of dissecting the ear. Case V. Acute inflammation of the dermis of the external meatus, extending to the brain and its membranes, caused by jJieJcine/ the ear 94 THE DISEASES OF THE EAR. with a pin. — Mary Wells, a single -woman, aged 24, of a scrofulous family, was attacked on the 1st April, 1841, with severe pain in the right ear, Avhich for some hours was distracting, and was followed by a sensation of something bursting, and by a discharge of blood and water, that afforded immediate relief. She had, prior to this, suf- fered no pain, and could only account for what happened from having picked her car with a pin, to relieve a tingling in it. The discharge was mixed with blood for two days, and ceased entirely at the end of the week, when she felt pretty well. In a few days, however, she had a rigor, followed by violent pain in the ear, which lasted twenty-four hours, when a copious purulent discharge took place, giving relief as before. She was now free from pain, and felt in good health. The discharge continued profuse until the 24th of April, when it again ceased. The next day she was seized with violent pain in the right ear and side of the head, accompanied by vomiting and symptoms of general fever. As the bowels were con- fined, she was purged. On the 28th, the pain in the head returned with great severity, and towards evening extended towards the right ear, unaccompanied with pain or redness, or increase of pain on pressure. She vomited twice. Ever since the first attack, the hearing on the right side had been aff"ected, and during the last few days she had complained of noise in the ear and giddiness, and car- ried her head bent backwards.^ The pain increased, and on the 30th she was admitted into St. George's Hospital, and ordered a calomel pill and haustus sennte. On the 1st of May, her state was as follows : — Pulse 104, full, sharp, and compressible ; tongue red and glazed ; the skin hot and dry; the conjunctiva slightly injected. There was slight intolerance of light, and a peculiar sensitiveness of the sense of touch, so that she shrank from the approach of a finger, though, when touched, she felt no pain. Iler eyes were bright, and in constant motion ; the right pupil was a little more dilated than the left. The respiration was quick (thirty-two per minute). The countenance was placid, though the manner was rather hurried. The catamenia were present. She was cupped, had cold lotion applied to the head, and calomel and a black dose were administered. During the following night she was delirious, though the senses could be recovered by an effort. May 2d, 1 P.M. — There Avas a slight degree of opisthotonos this morning, and the nurse remarked that, on her getting out of bed, ' Mr. Mauie, who saw the patient two or three time?, was of opinion that an abscess was forming in the internal ear. THE EXTERNAL MEATUS. 95 there was a peculiar rigidity of the muscles. She was, however, quite comfortable, and said that the headache went awaj about an hour after the cupping. Pulse 120, sharp but compressible ; tongue red and glazed. She was ordered a blister behind the right ear, and three grains of hydragryrum cum creta, were administered night and morning. 3d. — The feverish symptoms were somewhat abated, and she had some quiet sleep in the morning. The urine passed in natural quan- tity. 4th, 1 P.M. — Pulse again sharper, though the tongue was moist. The eyeballs were tender and suifused. No pain complained of, but she moans on being moved. The countenance is depressed, and she throws the clothes off her ; she is, however, quite sensible when spoken to. Ice was ordered to be applied to the head. To proceed with other medicines. 3 P.M. — Is heavier and less sensible. 6 P.M. — The ice was applied about 4 o'clock, soon after which she went into a comatose state, occasionally, however, waving her hands, and appearing to recognize her friends. 5th, 11 A.M. — Became perfectly comatose about 4 A.M. She is now perspiring profusely. Pupil of right eye contracted. She died at 12. Dissection of the body tivcnty-six hours after death. The iveather warm. Head. — There were a few patches of lymph upon both hemispheres of the brain, immediately beneath the arachnoid, which was more vascular than natural. The convolutions of the brain were flattened and its substance was watery, but not soft, with the exception of the corpus callosum, fornix, and the parts contained in and near the lateral ventricles, which broke up easily on a slight touch. The cavities of the ventricles were large, and contained a quantity of turbid fluid. The pons Varolii, medulla oblongata, and adjacent nerves Avere smeared with concrete, purulent lymph, effused into the cavity of the arachnoid. The cellular tissue around the optic nerves and their union, contained pus. The cerebellum Avas somewhat softer than natural. The dura mater coverina: the surface of the petrous bone was very vascular, and its vessels were distended Avith blood ; it Avas also separated from the bone by a small quantity of serous fluid. The substance of the bone Avas of a dark color, its bloodvessels being distended. On examining the in- ternal ear, the membrana tympani Avas found to be entire, but both 96 TIIEDISEASESOFTIIEEAR. it and the mucous meinbane liiiin/ the presence On the Nature and Treatment of Diseases of the Ear. Longman. 1S4". P. U7. ' Traite des Maladies de I'Oreille et de lAudition. 1821. Tome i, p. 328. THE EXTERNAL MEATUS. 141 of a drop of water in the meatus. — July, 1846 : E. F., aged 60, has been so deaf in the right ear, for some years, as to derive little use Fig. 39. Three Osseous Tumors projecting from the walls of the Meatus. from it. Has several times lately become suddenly so deaf in the left ear as scarcely to be able to hear a conversation. These attacks Fig. 40. ) A large Osseous Tumor and two smaller ones in the Meatus E.xternus. have usually come on in the morning after washing, and frequently lasted for some hours. 142 TUE DISEASES OF THE EAR. Right ear. — Two bonv tumors were observed in the meatus, occu- pying about one-half of its calibre, Membrana tympani dull. Left ear, meatus. — Extending from the upper part of the meatus is a long bony tumor, taking up two-thirds its calibre. This tumor is covered by a thick soft membrane, excepting at one point of about half a line in length, and a quarter of a line in breadth. From the anterior and posterior parts of the lower half of the tube projected two small elevations of bone, about three-quarters of a line in thick- ness, in the direction of the large tumor, so as to leave but a very small triangular space between them. This space was the only open- ing by which the sonorous undulations could pass to the membrana tympani ; and it was found that, during the operation of washing, it was liable to be filled up by water, which produced temporary deafness. The opportunity of carrying out a course of treatment for the diminution of the tumors was not given to me ; but by adopt- ing means to prevent the entrance of water into the meatus, the at- tacks of deafness were entirely prevented. Case III. Tumor in the meatus of the right ear ; orifice in mem- brana tympani of left ear. — Nov. 13, 1845 : P. H., aged 56, eleven years before, when in Russia, fell asleep in a garden. The next day felt severe pain in the left car, which lasted during fourteen days, when matter began to discharge. Has had several attacks of pain in the left ear since that period, which have been accompanied by beatinrj and sinfrin"". About six months ago, being then in the AVest Indies, had an attack in the right ear, followed by a diminution in the power of hearing, but there was no discharge. Two months ago he returned to England, and entirely recovered the use of the right ear, hearing better also with the left. Within the last four days pain came on in the left ear and rapidly increased, followed by pain in the right ear, and so great an extent of deafness in both ears as to require him to be shouted to. Right ear, meatus externus. — The middle two-thirds of the lower wall are occupied with a bony tumor filling half the calibre of the tube. Left ear. — Meatus externus red, and covered by discharge. Mem- brana tympani white, soft, and tliick, witli a small orifice, through which air passes. Case IV. Osseous tuinors in each ear ; feeling of confusion in the head. — Nov. 4, 1848 : T. T., aged 38. Last year deafness gradu- THE EXTERNAL MEATUS. 143 ally came on in the left ear, with occasional attacks of deafness in the night. This deafness has of late very much increased, and been also attended with a feeling of confusion, and a sense of oppression in the head. Right ear. — Projecting from the whole of the anterior and poste- rior surfaces of the external meatus, are two osseous growths, which come into contact in the centre of the tube. Hearing distance one foot. Left ear. — Two similar tumors likewise exist in the meatus of this Fig. 41. Two Osseous Tumors of the External Meatus in contact internally. ear ; but at the superior part they have so increased as to be in con- tact throughout, save a small orifice at the lower part. The deaf- ness in this ear has been greatly increased by the presence of a small quantity of cerumefi, which had filled up the small orifice just de- scribed, and its removal gave temporary relief ; but it Avas evident that the tumors would go on increasing until the entire passage of the meatus was blocked, unless remedial measures were at once adopted. For these no opportunity was afforded me. Case V. Large tumor in left ear, causing deafness ; diminished hy the use of iodine. — Feb. 1849. S. P., aged 17, states that deaf- ness commenced in the left ear, about two years and a half ago, and has been gradually progressing, till at length he cannot hear at all with that ear. Sometimes there is a violent itching, followed by discharge, and the tube of the ear is so sensitive, that the least 144 THE DISEASES OF THE EAR. touch causes exquisite pain. There is also a continuously unplea- sant sensation, as if the ear -were being distended. He complains of dulness of hearing in the right ear. Has been to various sur- geons and public institutions, but without obtaining any relief. Riglit ear. — A large osseous tumor occupies nearly the -vvhole of Fig. 42. An Osseous Tumor growing from the Upper Wall of the Meatus, and occupying nearly the whole of its calibre. the meatus, and is attached to its upper part. It is covered by the dermoid lininfr of the meatus, which is about a third of a line thick. Left car. — Healthy. Tincture of iodine Avas applied to the surface of the tumor, as also behind the ear, and four grains of iodide of potassium were given thrice daily for between two and three months. Great relief was the result ; the size of the tumor diminished ; the power of hear- ing greatly increased ; the tube of the ear lost its unnatural sensi- bility ; and the unpleasant sensation of distention completely va- nished. Case VI. A tumor in the right ear, filling nearly the entire tube ; slight protHhcranees in the left ear. — Nov. 25, 1848 : J. S., aged 65, states that ten years ago he had a gathering in the right ear, with great pain and much discharge. Continued, however, to hear pretty well until witliin about a month previous to applying to me, during THE EXTERNAL MEATUS. 145 which he has grown so very deaf that he cannot hear, unless the speaker's mouth approaches close to the ear. Ri(jlit car. — The external meatus contained a collection of epithe- lium, on the removal of which an osseous tumor was disclosed, filling nearly the whole of the tube. The tumor projected from the upper and lateral surfaces, and nearly touched the lower wall of the tube. Watch not heard in contact with the ear. Left ear. — The lower wall of the meatus presents two slight and quite hard elevations. Treatment. — Alterative doses of blue pills were prescribed, and tincture of iodine was directed to be applied behind the cars. The result I have not heard. Case VII. Tumor in the right ear following the extraction of a polypus. — June, 1847 : Rev. J. D., aged 47, consulted me for a continued discharge from the right ear. He stated that twenty years previously, after the forcible removal of a collection of Avax from the right ear, he experienced great pain, followed by an offen- sive discharge, that had lasted to the present time. On examination, a large, red, and firm polypus was perceived to fill the whole of the meatus, nearly as far as the orifice. It was attached to the wall of Fig. 43. Osseous Matter developed from the walls of the Meatus E.\ternus, leaving a triangular space in the centre. the meatus, near to the membrana tympani, and on its removal the latter was found to be very thick and vascular, with a small orifice at its lower part. The discharge wholly disappeared. 10 146 THE DISEASES OF THE EAR. In July, 1857, the patient again consulted me on account of a slight return of the discharge, accompanied by some degree of pain in the right side of the head, with an unpleasant sensation of fulness and pressure in the ear. On inspection, the meatus was found con- tracted to one-fourth its natural size by the growth of osseous matter from its walls, especially anteriorly and posteriorly, thus leaving a mere triangular opening, through which only the central part of the membrana tympani was visible, and that was Avhite and thick, I recommended the use of a strong solution of liquor plumbi to stop the discharge from the tube, and the application of the tincture of iodine behind the ear. In this case there had been long standing disease of the tympanic cavity, membrana tympani, and meatus, consequent on local injury. The disease was attended with so great an amount of deafness, that it appeared as if the cavities containing the expansion of the audi- tory nerve might also be implicated. Case A'^III. A protuberance of the lower wall of the meatus in the left ear. — December, 1848 : L. E. 11., aged 25, ten years previously experienced a singing in the left ear, Avhich during a cold became much worse, and was attended Avitli a feeling of numbness. A cold has lately aggravated all the symptoms in the left ear, and called forth a noise like a bell in the right ear. Right ear. — Membrana tympani dull ; hearing distance two feet. Left ear. — Meatus contained a large quantity of cerumen, after the removal of which the passage was observed to be red. At the lower wall near the membrana tympani there is a considerable bulg- ing of the osseous wall. Hearing; distance half an inch. In this case the diminished degree of hearing in the left ear did not depend upon the enlargement of the external meatus, for there was no doubt of a thickening of the mucous membrane lining the tympanic cavity. Case IX. Osseous tumor in the external meatus, causing a collec- tion of epidermis and serious cerebral st/mptoms ; relieved. — J. J. S., Esq., aged 5G, consulted me on the 27th April, 1850. lie stated that when a boy he had a discharge from the right ear, since which period he has been deaf at times, and been subject to a noise in the ear, together with a feeling of pressure on the head. Two months ago he complained of an attack of toothache, during which the deaf- ness was partially relieved ; but lately it lias become worse again, accompanied by a feeling of pressure in tlie cars ; he has also had THE EXTERNAL MEATUS. 147 frequent attacks of giddiness and confusion in the head. On exa- mining the right ear, the middle part of the meatus was seen to be occupied by a bony tumor which fills the whole of the tube, with the exception of a small space about three-quarters of a line in diameter, situated at its superior part. This space was observed to be closed by a white substance, which, on being touched with the probe, proved to be of great density. As it appeared probable that part, at least, of the symptoms above detailed depended upon the collection of epi- dermis behind the bony tumor, and its pressure upon the membrana tympani, it was thought desirable to attempt its removal. Small portions Avere picked away by the point of a probe, and the syringe was used ; it was, however, so hard that only minute particles could be detached. A solution of carbonate of soda Avas directed to be applied constantly for some days, and then a further quantity was extracted, Avhich mitigated the symptoms. By pursuing this plan, the whole of the matter beyond the tumors, which was found to be epidermis, was got rid of ; and the patient not only heard better, but the unpleasant symptoms of giddiness and cerebral irritation entirely disappeared. Judging from the large quantity of epidermis removed in comparison with the small space between the tumor and the membrana tympani, that substance must have been greatly com- pressed, and tlie membrana tympani also subjected to much pressure. In the year 1852, and again in the present year, the same gentle- man consulted me on account of similar symptoms, which were wholly removed by the use of the syringe alone. II, Molluscous Tumors. Molluscous tumors are sometimes formed in the external meatus, and lead to very serious results. I first met with these tumors when making dissections of the ear, and several specimens are in my possession, which well illustrate the nature of the disease. These excrescences seem to have their origin in the dermis of the meatus, and they gradually increase in size so as not only to fill the Avhole of the meatus, but to encroach upon and cause absorption of the bone. Thus, in some instances, the lower osseous wall of the meatus is affected, and in part absorbed, while in others the tumor extends upwards, and the whole of the upper wall of the meatus effaced by the pressure exerted upon it. I have met with cases 148 TUE DISEASES OF THE EAR. wliicli tlic tumor has extended into the cerebral cavity. These cases are liable to be overlooked, and classed "with those in which there is a simple accumulation of epidermis in the meatus. Fig. 44. Molluscous Tumor filling the whole of the Meatus Externus. The treatment of molluscous tumors consists in removing the large mass of scales contained in the tumor, and afterwards syringing the meatus abundantly Avith warm water twice or thrice daily. Fig. 45. C.ivity in the Mentus Externus from which a Molluscous Tumor has been removed. Case. Molluscous tuino?' in the external meatus ; discharge from he ear. — Mr. G., between 40 and 50, consulted me for a discharge THE EXTERNAL MEATUS. 149 from the right ear, accompanied by deafness. On examination, the meatus Avas observed to be nearly full of a white caseous-looking matter, from which oozed a discharge. By persevering use of the Fig. 46. Apertures in the upper wall of the Meatus Externus communicating with the Cerebral Cavity, produced by a Molluscous Tumor. syringe, aided by the forceps, a large Avhite mass was removed, which was found to consist of layers of white matter, composed of large scales, similar to those of other molluscous tumors. On the removal of the mass the discharge disappeared. In bringing to a conclusion these observations on the diseases of the external meatus, it will be well to draw attention to the morbid conditions disclosed by the dissection of 1013 diseased ears. They were as folloAvs : — Containing a collection of cerumen, ....... 71 Containing a collection of cerumen and epidermis, ..... 9 Distended and dilated by a collection of cerumen, ..... 5 Distended and dilated by a collection of cerumen and epidermis, . . 1 Containing a collection of cerumen and rye-seeds, ..... 2 Containing a collection of cerumen, the osseous walls being absorbed in parts, ............. 3. Containing a collection of cerumen and epidermis, the osseous walls being absorbed in parts, .......... 4 Containing a collection of cerumen, the osseous walls being absorbed in parts, so as to expose the cavities of the mastoid cells, ... 1 Containing a collection of hairs, ........ 1 Containing a collection of cotton-wool, ....... 1 150 THE DISEASES OF THE EAR. Containing a molluscous tumor 5 Containing a molluscous tumor, the osseous walls being absorbed in parts 3 Containing a molluscous tumor which projects through the bone into the cerebral cavity, ........... 1 Containing a molluscous tumor which projects into the mastoid cells, . 1 Containing a collection of pus, ........ 10 Containing a collection of pus mixed with epidermis, .... 1 Having polypi growing from its walls, ....... 1 Having polypi growing from its walls, the bone being carious, . . 1 The dermoid layer so much atrophied as to leave the bone denuded, . 2 The dermoid layer hypertrophied, ........ 2 The dermoid layer congested, ......... 7 The dermoid layer soft, .......... 1 The dermoid layer soft and red, ........ 2 The dermoid layer soft and detached from the bone, .... 2 The dermoid layer soft and thick, the bone being carious, ... 1 The dermoid layer ulcerated, the bone being carious 1 Osseous walls rough, .......... 1 Osseous walls carious, .......... 7 Osseous walls absorbed in parts, ........ 2 Osseous walls presenting an orifice superiorly, ...... 3 Osseous walls presenting an orifice inferiorly, . . .... 1 Osseous canal much contracted, ........ 3 Having bony growths from the osseous walls : canal much contracted. . 14 CHAPTER VIII. THE MEMBRANA TYMPANI. STRUCTURE AND FUNCTIONS. THE EPIDERMOID LAYER — THE DERMOID LAYER — THE FIBROUS LAYERS — THE RADIATE FIBROUS LAYER — THE CIRCULAR FIBROUS LAYER — THE MUCOUS LAYER — TENSOR LIGA- MENT — FUNCTIONS OF THE MEMBRANA TYMPANI. Anatomical Observations. — There are so many points of interest in Pathology connected with the structure of the membrana tympani, which bear upon its morbid conditions, but which have not hitherto been sufficiently recognized, that the subject deserves a full exami- nation. Looked at from without inwards, the membrana tympani may be described as consisting of the following layers : — 1. The epidermis. 2. The dermis. 3. The fibrous layer, composed of — a. The lamina of radiating fibres. h. The lamina of circular fibres. 4. The mucous membrane. The epidermis is a thin layer, covering the outer surface of the dermoid lamina ; it is continuous with the epidermis of the external meatus, and, when subjected to the process of maceration, can be removed in the form of a small blind pouch, which presents, as it were, a cast of the meatus and of the external surface of the mem- brana tympani. When floating in water, the pouch reassumos the form it had when in contact with other tissues, and its internal extremity is convex, corresponding with the external concavity of the membrana tympani. The layer of epidermis forming the outer coat of the membrana tympani is thin, and in the living subject so transparent that the dermoid layer can be distinctly seen through its substance ; its outer surface is very smooth, and capable of re- lo2 THE DISEASES OF THE EAR. fleeting light ; and there is usually seen at its anterior and inferior part, a triangular shining spot. In the course of dissection, I have more than once found this delicate epidermis to be the only layer remaining, over portions vary- FiG. 47. The Triangular Shining Spot at the anterior and inferior part of the outer surface of the Membrana Tympani. ing from a line to a line and half in breadth, and yet appearing to have been sufficient to close the cavity of the tympanum and to pre- serve the power of hearing nearly perfect. The knowledge of this condition of the membrana tympani ought to lead to a cautious use of the syringe when no cerumen is present, since its application may cause a rupture of the epidermis. The dermoid layer, as its name implies, is continuous with the dermis lining the external meatus, and is situated between the epi- dermis and the radiate fibrous layer. It is extremely thin, and secretes the epidermis. Previous -to the publication of a paper by me on the structure of the membrana tympani, in the " Philosophi- cal Transactions," for 1851, it had l)een supposed that the epidermis was secreted by the radiate fibrous layer. The presence of the der- mis is best demonstrated by carefully dissecting, under water, the membranous meatus from the upper surface of the osseous tube, as far as the attachment of the membrana tympani ; at which point the peri- THE MEM BR AN A TYMPAXI. 153 osteum of the meatus is seen to become continuous with the radiate fibrous hxmina; this being cut through, the dermoid hiyer is detected passing down over the outer surface of the radiate fibres, and sepa- rating them from the epidermis. If the upper portion of tliis hayer be drawn gently downwards by one hand, by means of a fine needle in the other, the delicate cellular tissue which connects it with the fibrous lamina can be broken up, and the dermis removed entire. The presence of this lamina may also be shown by introducing be- tween it and the radiating fibrous layer, at the superior part of the membrana tympani, a fine bristle, by passing which down the cel- lular tissue is lacerated. In a healthy state, when uninjected by blood or by artificial means, the dermoid lamina is thin and transparent, and its structure, under the microscope, looks like areolar tissue. When injected, however, this membrane is seen to have numerous bloodvessels rami- fying through it, so as to foi-m an elaborate plexus : these vessels, when enlarged, impart the red appearance to the surface of the mem- FiG. 4S. The Dermoid Layer of the Membrana Tympani continuous with the Dermis lining the upper wall of the Meatus Externus. brana tympani so frequently met with during life. It is upon the supply of nerves to this lamina that the exquisite sensibility of the membrana tympani depends. A knowledge of the existence of the membrane just described is of interest to the anatomist, who recognizes in it the secreting organ of the epidermoid layer of the membrana tympani ; and to the sur- geon, who through its presence is enabled to understand phenomena occurring in certain diseases of the ear. There are pecidiar diseased conditions in which the dermoid layer of the membrana tympani be- comes much hypertrophied. The Y*ro])cr Jibroiis layer of the membrana tympani can be easily separated into two lamina), which are named from the direction of their component fibres. Previous to describing these structures, it 154: TUE DISEASES OF THE EAR. is desirable to cite the opinions of eminent anatomists concerning them. In the Croonian Lecture, published in the 19th volume of the "Philosophical Transactions," Sir Everard Home advanced the opinion that the membrana tympani in the human subject was mus- cular. Ilis words are : " When viewed in a microscope, magnified twenty-three times, the muscular fibres are beautifully conspicuous, and appear uniformly the same throughout the whole surface. There being no central tendon as in the diaphragm, the muscular fibres appear only to form the internal layer of the membrane, and are most distinctly seen when viewed on that side."^ The use of this radiated muscle. Sir Everard states, is " to give those difibrent de- grees of tension to the membrane which empower it to correspond with the variety of external tremors."- Since the first publication of this opinion as to the muscularity of the membrana tympani, ana- tomists, though generally conceding that it is fibrous, have widely differed as to its composition. According to Mr. Quain and Dr. Sharpey, " It is made up of fine closely-arranged fibres, the greater number of which radiate from near the centre to the circumference ; but within these are circular fibres, which are more scattered and indistinct, except close to the margin of the membrane, where they form a dense, almost cartilaginous ring."^ Mr. "Wharton Jones writes : " The proper membrane can be divided into two layers — an outer thin one, consisting of radiating fibres, and an inner thicker layer, which is less distinctly fibrous, though when torn it does indi- cate a fibrous disposition, and that in a direction opposite to the former. . . . The fibres which cross the radiating ones are more aggregated at the centre ; they run parallel with the handle of the malleus, and turn round its extremity. At the circumference of the proper membrane, there is a thick, firm, ligamentous or cartilaginous ring, which is fixed in the groove of the bone. The ligamentous ring appears to be formed by an aggregation of the circular fibres interwoven with the peripheral extremities of the radiating ones."^ By careful dissection the fibrous layers of the membrana tympani may be separated into two distinct laminse, the fibres of which have no intercommunication. The external layer may be called the radi- ate fibrous lamina, since its fibres radiate from the malleus to be at- • Loc. cit. p. 5. ' Loc. cit. p. 11. » Elements of Anatomy, 5th Edition, 1848, vol. ii, p. 932. * Cyclopsedia of Anatomy and Physiology, vol. ii, p. 545. THE MEMBKANA TYMPANI. 155 taclied to the cartilaginous ring; and the internal, lk\Q circular fibrous lamina. The radiate layer is the thicker and stronger of the two. So readily may the layers be separated from each other, that they are detached Avith more facility than the circular layer can be freed from the mucous membrane. {a.) The radiate fibrous la^cr. — If the whole of the membrana tympani be carefully removed, there will be observed at its cir- cumference a white, dense ring, apparently cartilaginous, which is received into the osseous groove of the temporal bone appropriated to it. It Avill be remembered, however, that this groove occupies only about five-sixths of the circumference of the inner extremity of the meatus, the upper sixth being smooth instead of grooved. The cartilaginous ring at the upper part is attached to the malleus, the anterior extremity being inserted into the anterior, and the pos- terior extremity into the posterior, part of the cervix of this bone : to the outer surface of this ring is attached the periosteum lining the external meatus. If the radiate lamina be examined with a magnifying power of ten or twelve diameters, fibres will be observed whose peripheries are attached to the cartilaginous ring, and their other extremities to the malleus. The uppermost of these fibres, however, must be excepted from the observation just made ; for in- stead of passing from the superior part of the ring to the malleus, they take their course in front of the processus brevis, and form a distinct layer of membrane covering its outer surface. The dispo- sition of this portion of the radiating fibrous lamina is interesting alike to the anatomist and surgeon, for it is observed to be con- tinuous with the periosteal lining of the upper part of the external Fig. 49. The Radiate Fibrous Layer of the Membrana Tympani. meatus. Mr. Shrapnell, perceiving that this portion of the mem- brana tympani Avas not so tense as the rest, considered it to be a distinct structure, and named it the "membrana flaccida." Directly below the processus brevis of the malleus, the radiating fibres are attached to the ridge occupying the external surface of 156 THE DISEASES OF THE EAR. the bone ; but at 4his part the fibres from each half of the mcm- brana tympani are inserted so near to each other that no portion of the malleus is visible -when viewed exteriorly. Towards the inferior extremity of the long process, however, the fibres being attached to the sides and not to the anterior surface, a small portion of the ex- ternal surface of the long process, at its inferior part, is left bare and in contact with the dermoid layer ; as may be distinctly seen in Fig. 50. The Fibres composing the Radiate Fibrous Lamina (magnified about 300 diameters).' the healthy living ear by the aid of the speculum auris and a mag- nifying lens. The fibres extending from the malleus, and forming Fig. 51. The Radiate Fibrous Lamina ; external surface displajing the peculiar markings caused by the interlacement of the fibres. the posterior, are one-fourth larger than those forming the anterior segment of the membrane. The thickest part of this layer sur- ' In the other drawings from the microscope, the same magnifying power was used. THE MEMBRANA TYMPANI. 157 rounds the extremity of the long process of the malleus, and the most attenuated lies bet-ween the posterior margin of the long pro- cess of the malleus and the circumference of the membrana tym- pani. Structure of the radiate lamina. — The fibres composing the ra- diate lamina, when examined in a fresh state by the microscope, are translucent, and, with the exception of a few transparent globules, present no peculiarity of structure. The longitudinal parallel Avavy lines, however, characteristic of ordinary fibrous membranes, are absent. The fibres are flat, and vary from 40'ou to gj>g^ of an inch in breadth. In passing from the circular cartilage to the malleus these fibres interlace, giving rise to the peculiar diamond-shaped markings observable on the outer surface of the membrane. When treated with acetic acid, this lamina becomes opaque, and sometimes, Fig. 52. m^r \k'MM^ ijlf '1 '^^pfii^ii The Radiate Fibrous Lamina, after having been treated with Acetic Acid. but not invariably, elongated oval nuclei are detected, the long axes of which correspond with the course of the fibres. In no instance, liowever, was an oval nucleus visible in an isolated fibre. Fig. 53. The Circular Cartilaginous Band, after having been treated by Acetic Acid. The circular white hand at the circumference of the radiate fibres consists of a firm, slightly elastic mass of tissue, and presents an in- distinct appearance of fibres intermixed with oval-shaped nuclei. 158 THE DISEASES OF THE EAR. Under acetic acid this structure loses its white aspect, becomes translucent, and discloses a great number of the oval nuclei. (b.) The circular Jibrous lamina. — This membrane, as previously stated, is attached to the radiating fibres by fine cellular tissue, and can be readily separated ; for, as before observed, the fibres of each lamina are quite distinct and never intermingle. As its name im- plies, this lamina consists of circular fibres, which are firm and strong at the circumference, but so attenuated towards the centre, as to be detected only by careful observation. The strong fibres at the circumference of the layer form a complete circle, and are at- attachcd to each side of the body of the malleus, and to the sides of the upper third of the processus longus. When closely examined Fig. 54. ^^ The External Surface of the Circular Fibrous Lamina the fibres being attached to the Processus Longus of the Malleus. (Slightly magnified.) by a magnifying power of thirty to forty diameters, the circular fibres are seen to be intersected by others of an extremely delicate character, which, increasing in number towards the centre of the lamina, become there so intimately blended with the circular fibres that the latter are not easily distinguishable. The central thin por- tion of the circular lamina is not attached to the malleus, but the fibres from each side are continuous, and form a membranous layer by a series of concentric fibrous circles ; the outer surfiice being in contact with the inner surface of the lower half of the long process of the malleus, to which it adheres by loose cellular tissue. The circular fibrous lamina is entirely unconnected with the cartilagi- nous ring into which the radiating fibres are inserted ; but is con- tinuous with, and may be considered a modification of, tlie periosteal lining of the tympanic cavity. When the lamina of circular fibres is detached from the radiating layer, it will be found slightly con- cave externally, though less so than the outer layer. In its sepa- rate condition it is also not quite so concave as when it was con- nected with the inner surface of the radiating fibres ; but when its central portion is pressed inwards, so as to increase the concavity. T n E M E M B R A X A T Y M P A N I. 159 its inherent elasticity causes it quickly to resume its former saucer- like shape. If the two layers, when detached, be placed side by Fig. 55. The Internal Surface of the Circular Fibrous Lamina : the Long Process of the Mal- leus is seen through the translucent central part. (Slightly magnified.) side, the greater degree of external concavity in the radiating fibrous layer is very perceptible. Structure of the circular lamina. — When highly magnified, the fibres of the circular lamina are found to be smaller than those of the radiate fibrous layer, and to vary from the 6000th to the 10,000th of an inch in breadth. The outer fibres run parallel with each other, and do not interlace ; they are diaphonous, and free from any wavy longitudinal lines. Under acetic acid, the fibres enlarge and assume Fig. 56. The Fibres composing the Circular Fibrous Lamina. a certain degree of opacity ; and in some instances this lamina also presents distinct oval nuclei elongated in the direction of its fibres ; but as in the radiate lamina, never in the separate fibres, and most commonly they are not present. It is often not easy to decide Avhether a structure is muscular : hence doubts may arise as to the true nature of the two fibrous laminse of the membrana tympani. My own researches do not seem to favor the view of that membrane being a contractile tissue. The 160 THE DISEASES OF THE EAR. facts -vvliicli appear to militate against the idea of its being muscu- lar, arc : — 1st. The absence of distinct nuclei in the fibres. Fig. The Fibres of the Circular Fibrous Lamina, treated with Acetic Acid. 2d. The great denseness and hardness of the latter, and their firm and unyielding structure, they being so strong as to be Avith diflH- culty torn across. (c.) The mucous membrane forming the inner layer of the mem- brana tympani is, in the healthy ear, so extremely thin as to be with difficulty detected ; though by careful dissection it may be removed entire from the inner surface of the circular fibres, with which it is connected with considerable firmness by fine cellular tissue. It will now be evident that of all the laminte Avhich constitute the membrana tympani, not one is proper to that organ ; all of them being directly continuous with other structures, of which they appear to be modifications. Thus : — Fig. 58. The Radiate Fibrous Lamina, the Circular Fibrous Lamina, and the IMucous Membrane of the Membrana Tympani, seen to be continuous with the other structures. (Slightly magnified.) 1st. The epidermis is continuous with that lining the external meatus. 2d. The dermis is continuous with the dermis of the meatus. THE MEM BR AN A TYMPANI. 161 3d. The fibrous lamina consists of the radiate fibrous lamina, which is a prolongation of the periosteal lining of the external meatus ; and the circular fibrous lamiiia, a prolongation of the peri- osteum of the tympanum. 4th. The layer of mucous membrane forms part of the lining of the tympanic cavity. Previous to considering the functions of the fibrous laminae of the membrana tympani, it is desirable to advert to another point in the structure and relations of this organ. It has been already stated that the membrana tympani is attached, at its circumference, to the temporal bone, and, at its central part, to the malleus, which latter bone is so suspended by means of the processus gracilis and the short process of the incus, that the long process can move inwards towards the tympanic cavity, and outwards towards the meatus. It must be evident, therefore, that in order to prevent the concave membrana tympani, with the above attachments, from remaining in a state of relaxation, either the tensor tympani muscle must be in a state of continual contraction, or some other provision must exist for retaining the membrana tympani in the moderately tense con- dition fitting it to receive the sonorous undulations. This provision actually exists, and, as far as I am aware, has hitherto escaped the attention of anatomists : it is the tensor ligament of the membrana tympani. The ligament in question is about three-fourths of a line in length, and is attached internally to the cochlcariform process, and exter- nally to that part of the inner surface of the malleus where the long process joins the neck. In the interior of this ligament, which Fic 5'J. The Attachments of the Tensor Tympani Ligament ; the tendon of the Tensor Tymyiani Muscle is drawn upwards so as to leave the ligament isolated. (Slightly magnified.) is tubiform, is placed the tendon of the tensor tympani muscle. Anteriorly the ligament is thin, consisting of very delicate fibres ; but the remainder is thick, dense, and composed of firm ligamentous 11 162 THE DISEASES OF THE EAR. tissue. So long as it remains entire and the membrana tympani uninjured, the latter structure retains its natural degree of con- cavity and tenseness ; but when the ligament is cut through, or there is a solution of continuity, resulting from disease, the mem- brana tympani becomes very flaccid, even though the tendon of the tensor tympani muscle remains entire. When the tensor tympani muscle is pulled, in a preparation of the parts, the membrana tym- pani is rendered very tense, and the tensor tympani ligament re- laxes ; but so soon as the muscle relaxes, the membrana tympani returns to its original state, and the ligament again becomes tense. On the functions of the Jibrous lamina' of the membrana tympani. — It is obvious that one use of the fibrous laminse of the membrana tympani is to present a firm but delicate membranous septum for the reception of sonorous undulations. The arrangement of the two sets of fibres at right angles to each other, has the efi'ect of impart- ing great strength, combined with extreme delicacy and tenuity, to the membrane. As stated, there is no evidence to prove that the fibres of which the membi'ana tympani is composed possess in them- selves any contractile power ; neither do the component fibres of the laminixi appear to evince more than an extremely slight degree of elasticity. An examination, however of the structure after death, shows that it has an inherent power of returning to its natural state after being unusually distended. Thus, if the membrana tympani be exposed without interfering Avith its natural state of tension, and the canal containing the tensor tympani muscle be laid open, so that the muscle can be drawn towards its origin, the external concavity of the membrana tympani can be increased until it becomes very tense ; but as soon as the muscle is let go, the membrana tympani will be observed to resume its former condition. This action is explainable partly by the slight elasticity of the circular cartilaginous band, into which the peripheral extremities of the radiating fibres are inserted, and partly by the slight elasticity of these fibres themselves ; but more especially by the peculiar arrangement of the circular fibrous lamina, which has always a tendency, Avhen left to itself, to assume a more shallow form. Thus when the membrane is rendered very concave, the circular fibres are slightly separated from each other ; but when the extra tension ceases, the fibres intersecting the circular ones aid in drawing the latter together again. The disposition of the central region of the circular lamina also assists it in bringing back the membrana tympani to its natural THE MEMBRANA TYMPANI. 163 State after tension hj the tensor tjmpani muscle. It has been stated that the middle part of these circular fibres, instead of being attached to the handle of the malleus, is applied against its inner surfjice, and thus the membrane is further rendered tense by the pressure of the long process of the malleus against its outer surface during the action of the tensor tympani muscle ; and when this muscle ceases to act, the central part of the circular layer reacts on the malleus and constrains it to resume its usual position. Besides the office of bringing the membrana tympani to its natural state after the action of the tensor tympani muscle, the circular fibrous layer would appear to be always acting as an antagonist to the tensor tympani ligament ; so that by the continued action of these two tissues — the one drawing it inwards, the other outwards — the membrana tympani is kept in a state adapted to receive all the ordi- nary sonorous undulations, independent of any exercise of muscular power. T/ie functions of the memhrana tympani. — Anatomists generally consider that the use of the membrana tympani is to receive the sonorous undulations from the air of the meatus, and conduct them to the ossicles, by which they are conveyed to the labyrinth. Whether vibrations are conducted to the labyrinth through two media, or through the air alone, there can be no doubt that the membrana tympani is the agent whereby the vibrations are con veyed from the meatus externus to the tympanum. I shall, in a future part of this volume, try to prove that another function of the membrana tympani is, in conjunction with the muscles and bones of the tympanum, to act as the analogue of the iris of the eye : and thus, firstly, shut out from the internal ear, or at least modify, the effect of loud vibrations ; and, secondly, render the ear susceptible of the more delicate undulations. Whatever opinion may be held respecting the functions of the membrana tympani, there can be no doubt that its integrity is essential to the due performance of its functions, as also that it should retain its natural degree of resiliency, and that its muscles should be able to move it with ease. CHAPTER IX. THE MEM BR AN A TYMPANI {continued). THE EPIDEUMOID LAYER — DERMOID LAYER — {(l) AC'fTE IXFLAM JIATIOX — TREATMENT — CASES (A) CHRONIC INFLAMMATION — CASES — (c) ULCERATION — CASES. FIBROUS LAMINAE — {a) ACUTE INFLAMMATION — {!)) CHRONIC INFLAMMATION — {c) ULCERATION {fl) CALCAREOUS DEGENERATION — (c) RELAXATION OF THE MEMBRANA TYMI'ANI — TREATMENT — CASES. In describing tlie diseases of tlie membrana tympani, I shall speak in succession of its epidermoid, dermoid, and fibrous layers, leaving the consideration of the mucous layer till the diseases of the tym- panic cavity come under review. I. The Epidermoid Layer. — This layer is sometimes secreted in such large quantities as to form a mass several lines in thickness on the outer surface of the dermis. In some cases I have known this mass to be composed of six or seven lamint^, closely packed upon each other. The symptoms attendant upon this accumulation Fig. 60. I '■ ' %^_ Epidermoid Layer of the Membrana Tympani liypertroiihied. (Magnified three diameters.) are analogous to those of accumulation of epidermis in the meatus ; tlicre is also often a great degree of cerebral irritation from the pres- sure on the chain of ossicles. The treatment is similar to that em- ployed ■where there is accumulation of epidermis in the meatus exter- nus. A syringe and warm water arc usually sufficient to loosen and bring away the mass. Should they not be so, a few drops of water or soap and water, dropped into the meatus for a day or two, will THE MEM BR AN A TYMPANI. 165 loosen and facilitate the removal of the mass. As a general rule, the symptoms of deafness and discomfort in the head •wholly dis- appear with the extraction of the collection. II. The Dermoid Layer. — This layer of the membrana tympani, like the dermis of the meatus, is subject to acute and chronic inflam- mation, and also to ulceration. On account of the intimate relations existing between the dermoid and fibrous layers of the membrana tympani, it is of great importance to put a stop to these affections of the dermis, since they are apt to be prolonged to the deeper- seated layers of the organ. [a.) ACUTE INFLAMMATION OF THE DERMIS. Acute inflammation of the dermis usually occurs in debilitated subjects, and is produced by the application of cold, or cold water, or any foreign body to the surface. The exciting causes are sudden exposure to cold air after being in a warm room, or cold water find- ing its way into the ear while bathing ; often also it arises from the extension of inflammation from the dermis covering the meatus. The symptoms of this kind of inflammation are slight pain at the bottom of the meatus (aggravated by coughing, sneezing, and at times b}' swallowing), also not unfrequently an itching, with slight dulness of hearing. On examination, the outer surface of the mem- brana tympani is seen to be dull, and the dermoid layer opaque ; its bloodvessels being distended with blood. All the vessels bordering on the malleus are very much larger than natural, and frequently form tAvo red lines, one running on each side of the long process of the malleus. After a few days a discharge of mucus often takes place. This affection, if left unsubdued, is apt to advance to ulcera- tion, and the fibrous layers are also liable to be destroyed. Treatment. — The treatment is very similar to that for acute in- flammation of the dermoid meatus. One or more leeches should be applied to the margin of the orifice of the meatus, warm water should be syringed into it thrice or oftener daily, hot fomentations used all around the ear, and, if requisite, aperient medicines and calomel ad- ministered. Most usually the inflammation (seldom accompanied by discharge, though a small quantit}^ sometimes issues from the surface of the membrane) soon succumbs to this treatment, and the fibrous lamince escape uninjured. 166 THE DISEASES OF TUE EAR. Case I, Acute injlammation of the dermoid layer of the memhrana tympani. — G. W., Esq., aged 00, consulted me on February 15th, 1858, on account of pain in his right ear. History. — Witliout assignable cause, slight pain occurred in the right ear several days ago, which has remained till now, being aggra- vated at times. It is increased by coughing, and slightly when swal- lowing. A sensation of fulness is also complained of. On examina- tion^ I found the dermoid layer of each membrana tympani to be more opaque than natural, and numerous bloodvessels, especially at the upper part, were observed to be distended with blood. There was but slight diminution in the power of hearing. Treatment. — As the pain was not very severe, the ear was ordered to be syringed out with warm water twice daily, a linseed-meal poul- tice to be applied over the ear at night, and a stimulating liquid to be rubbed over the back of the ear. The pain gradually ceased, and the membrane returned to its natural state. Case II. Acute inflammation of the dermoid layer of the memhrana tyynpani. — B. S., Esq., a medical man, aged 48, saw me in February, 1852. History. — When a student, twenty-six years previously, he had an attack of cold, and became suddenly deaf in both ears, but re- covered in the course of two months. Sixteen years ago, had an attack of vertigo, and suddenly lost the use of the left ear ; the hearing partially returned, but still remains dull. A fortnight be- fore consulting me, he had relaxation of the throat, with an uncom- fortable feeling in the left ear, and again became dull of external hearing, though the sound of his own voice Avas like thunder. On examination, the membrana tympani was observed to be swollen and much redder than natural ; its bloodvessels being large and dis- tended. "VVatch heard at a distance of two feet. Treatment. — Slight counter-irritation was kept up behind the ear, and a cooling lotion applied to the meatus for ten days ; at the end of that time the patient quite recovered. Case III. Acute inflammation of the dermoid layer of the mem- hrana tympani. Discharge of viscid mucus. — Master S., aged 3, was brought to me by his father, a physician in London, on the 19th April, 1853. History. — A few days previously, Avlien not feeling very well, com- plained of slight pain in each ear, which continued for two days, and was followed by a discharge of mucus, with slight dulness of THE MEMBRANA TYMPANI. 1G7 hearing. The latter symptoms have remained until the present time. On examination, each external meatus Avas ohserved to be par- tially filled ■with matter, ■which "was removed by the syringe, and found to be composed of masses of mucus, similar in character to those issuing from the meatus in cases of acute inflammation of the dermis. They Avere more flocculent, whiter, but not so elongated as in the secretion from the mucous membrane of the tympanum. After the meatus had been cleansed, the outer surface of the membrana tympani "was seen to be of a deep red color, and to project out"wards into the cavity of the meatus. More minute inspection sho"\ved that this red appearance depended upon the tumefaction of the dermoid layer of the membrane, which being denuded of epidermis, the pro- cessus brevis of the malleus ■was observed at its uppermost part. The hearing Avas very dull. Treatment. — A leech Avas ordered to be applied to the margin of the orifice of each meatus, and hot poultices to be kept over the ears. By these means the pain Avas subdued, and the inflammatory symp- toms abated. In the course of three days a small portion of vesica- ting paper Avas applied behind each ear. The poAver of hearing re- turned by degrees, the discharge disappeared, and the dermoid mem- brane regained its natural appearance. Case IV. Acute inflammation of the dermoid layer. Secretion of mucus. — A. Moorman, aged 58, Avas admitted under my care at the St. George's and St. James's Dispensary, on May 24th, 1850. History. — During the last five months has felt much debilitated. About seven Aveeks previous to seeing me, pain suddenly attacked the right ear, and Avas folloAved by a "steaming and hissing sound." After this sound had remained for three wrecks, a discharge issued from the ear, Avhicli has continued to the present time, accompanied by a good deal of itching, and by a sensation as of something grind- ing within the ear. On examination, the watch Avas only heard Avhen in contact with the ear ; the dermoid layer of the membrana tym- pani was observed to be flat, red, and very much swollen ; and there was a watery discharge, consisting principally of epidermoid cells. The surface of the meatus was rather redder than natural. Treatment. — The ear to be syringed Avith warm Avater twice daily; and vesicating paper to be applied each night behind the car. May 31. — Better ; the noise less loud ; the power of hearing in- creased. 168 THE DISEASES OF THE EAR. June 7. — Improves daily : the quantity of discharge is much diminished ; and the noises have ceased, with the exception of short occasional attacks. The membrana tympani is recovering its natural aspect. [b.) SIMPLE CHRONIC INFLAMMATION OF THE DERMOID LAYER, WITH OR WITHOUT AN ACCUMULATION OF EPIDERMIS. This affection is also commonly produced by cold, but is of little importance, excepting when it results in the secretion of large quan- tities of epidermis. A simple tumefaction of the dermoid layer usually aflFects the hearing power too slightly to cause the patient to apply for relief: in many instances where the layer has been hyper- trophied, the patients have suffered no inconvenience. If, hoAvever, it becomes so tumefied as to render the membrana tympani tense, then a perceptible deafness is induced. In the majority of cases of hypertrophy of the dermoid membrane, there coexists a thickening of the mucous membrane of the tympanum, which causes the deaf- ness. The presence of several layers of epidermis on the outside of the dermis, is also a source of considerable deafness, and very frequently of uncomfortable sensations in the ear and head. Case I. Simple chronic inflammation of the dermoid layer, with an accumulation of ej)idcrmis on its surface. — Colonel T., aged 45, strong, and in good health, consulted me on July 1st, 1855, on ac- count of a buzzing sensation in both ears, especially in the right, which had lasted for three months, accompanied by a feeling of op- pression in the head and dulness of hearing. On examination, the watch was heard only when in contact with the ear, and a large quantity of epidermis was observed at the bottom of the meatus. By means of the syringe, several layers were extracted, and the surface of the dermis, which was red and thick, exposed. On the removal of the epidermis, the noises and unpleasant sensation in the head vanished, and the hearing Avas much improved; the hearing dis-' tance Avith the Avatch being six inches. Case II. Clironic inflammation and hypertrophy of the dermoid layer. — R. J., Esq., aged 25, visited me on March 20, 1853, on ac- count of dulness of hearinj;. History. — Five years ago, after a large portion of cerumen had been scooped out, had irritation in the ears^ and remained deaf for some time afterAvards. Three months ago, when suffering from deaf- THE MEM BR AN A T Y M P A N I. 1G9 ness, was relieved bj the use of the syringe ; lately the left ear has again become dull, and he has complained of pain in it, and in the left side of the face. On examination, the right ear heard the "watch at a distance of two inches ; the left at the distance of an inch. The dermoid layer of each membrana tympani was hypertro- phied, and that of the left ear was very red. Treatment. — A slight discharge was kept up from the surface of each mastoid process, and a weak solution of nitrate of silver (gr. v. ad. 5J) was applied to the surface of thejiffected membrane. April 9. — Hearing improved. The watch is heard by the right ear at a distance of three inches ; by the left, at a distance of seven inches. {c.) CHRONIC CATARRHAL INFLAMMATION OF THE DERMOID LAYER. This form of inflammation is far from being rare. Like the same disease of the dermoid layer of the meatus, it often occurs in chil- dren out of health, and also results from the application of cold to the surface of the membrane. It very frequently takes its origin in an attack of acute inflammation, which, instead of subsiding, be- comes chronic. The discharge usually consists of the epidermoid cells, which are thrown off in conjunction with a quantity of fluid, instead of forming a distinct epidermoid layer. On removal of the discharge, tlie dermis is found to be swollen, and entirely denuded of epidermis ; the color of the surface varying from a deep to a palish red. The cases of this disease require the deepest attention, since they are apt to terminate in the formation of granulations or of polypi on the surface of the membrane, or in ulceration ; the latter process endangering the fibrous lamina;. This affection is also not unfrequently associated with a corresponding one of the dermoid layer of the meatus ; which may be subdued without the disease of the membrana tympani being cured. Case I. Chronic catarrhal inflammation of the dermoid layer, with thickening of the mucous membrane of the tympanum. — Rev. W. A., jBt. 32, visited me on the 18th of November, 1854. History. — Since childhood the left car has been useless. During the past year the right car has been dull of hearing at times, and he has complained of irritation of the ear, for which he has been in the habit of using an earpick. Lately his deafness has so increased. 170 THE DISEASES OF THE EAR. that he has to be loudl}' spoken to Avithin a yard of the head, and also complains of a discharge from the right ear. On examination, the dermis of the meatus in the right ear was observed to be red, while the dermoid layer of the mcmbrana tympani was partly red and partly white : there was also an abundant discharge of mucus. Treatment. — The ear to be syringed out with warm water thrice daily, three leeches to be applied to the orifice of the meatus, and vesicating paper to be kept behind the ear. Nov. 2G. — Much better : thinks he now hears as Avell as he has done for some years. The dermoid layer of the membrana tympani is less red ; the discharge is less abundant. Case II. Catarrhal injlammation of the dermoid layer after bath- ing. — Miss J. G., let 27, consulted me on September 15, 1855, on account of a dulness of hearing in the left car, Avith discharge. History. — A year previously, immediately after bathing in the sea, felt a slight pain in the left ear, which continued for three or four days, and was followed by a discharge, which has remained until now, accompanied by a dulness of hearing. On examination., the surface of the dermoid layer of the membrana tympani was found to be covered with discharge, which being removed, the membrane was seen to be red, and its bloodvessels distended. Under the same treatment as in the last case, the patient was cured in two months. Case III. Catarrhal inflammation of the dermoid layer after measles. Polypoid groivth from the surface. — Miss M. E. S., aged 10, not strong, Avas brought to me on April 2, 1853. History. — Three years previously had an attack of measles, fol- lowed by discharge from the left ear, and considerable dulness of hearing in both. Eight months ago had an attack of low fever, Avhich remained for two or three months, and much increased the deafness. At the present time has to be spoken to distinctly within a yard of the right ear. Every night there is discharge, and a cer- tain amount of earache. Is better in warm weather. On examination, there was found in the right ear a large quantity of discharge, which being removed, the dermoid layer Avas observed to be much hypertrophicd, and red groAvths covered considerable portions of it, especially posteriorly. Hearing distance four inches. Left ear. — Membrana tj'mpani Avhite at the upper part, and the dermis much thickened; discharge abundant: hearing distance half an inch. THE MEM BR ANA TYMPANI. 171 Treatment. — A solution of chloride of zinc, two grains to the ounce, -was injected into each car daily, and a discharge was kept up from the surface of the mastoid process. Under this treatment Fig. fil. Granulations on the surface of tbe Dermoid Layer of the Membrana Tympani. (Seen through the Speculum.) the discharge disappeared, and the poAver of hearing was greatly improved. Case IV. Catarrlialinjiammation of the dermoid layer, following measles. — Master M. N., aged 6, pale, thin, and of a scrofulous dia- thesis, was brought to me on the 12th of May, 1851, on account of a discharge from the right ear. History. — Since infancy has been subject to attacks of earache : five montlis ago had an attack of measles, followed by a discharge from the right ear, which, though diminishing at times, has never wholly ceased. No dulness of hearing has been perceived. On examination, the hearing distance of the right ear was found to be reduced to four inches ; the meatus contained a large quantity of offensive discharge ; the outer surface of the membrana tympani was flat ; the dermis was white, and much thickened. Treatment. — Tonic medicines were administered ; the ear syringed out with half a pint of tepid water thrice daily, and afterwards with a solution of tannin, three grains to the ounce ; and a stimulating liniment was rubbed over the mastoid process twice daily. This 172 THE DISEASES OF THE EAR. treatment, persevered in for two months, removed the discharge, diminished the hypertrophy of the memhranc, and improved the power of hearing. The patient was brought to me three or four times subsequently, suffering from a recurrence of the attack, but it always yielded to similar treatment. (t7.) ULCERATION OF THE DERMOID LAYER OF THE MEMBRANA TYMPANI. Ulceration of the dermoid layer is an affection only occasionally met with, and is either the result of long-continued catarrli of the dermis, or of the application to its surface of irritating matters, or of cerumen. The symptoms are very similar to those described in the previous section ; there is, however, frequently a discharge of blood, and the pain is more severe. Case I. Ulceration of the dermoid layer from the presence of ceru- men. — Mrs. G., aged 40, saw me on May 26th, 1855. History. — Fourteen days previously she had a singing in the left ear, which came on suddenly after fatigue, and has remained until the present period ; it is accompanied at times with confusion in the head. On examination, the meatus was found to be full of cerumen, and the Avatch was only heard when in contact with the ear. On remov- ing the cerumen by a syringe and warm water, the outer surface of the merabrana tympani was observed to be red. At its anterior part there Avas a small surface, about three-quarters of a line in dia- meter, Avhere the dermis had been wholly destroyed by ulceration ; and there was also a small depression, at the bottom of Avhicli the membrane was red. Hearing distance reduced to eight inches. No applications were made, and the ulcer healed in a few days. Case II. Ulceration of the dermoid layer ; fibrous layers exposed. — J. A., Esq., aged 35, was sent to me on March 2G, 1850, by Mr. Mossop, of "Whitehaven. History. — Twenty years ago, had a polypus in the right ear, wliieh Avas removed ; but it grcAV again, and Avas a second time removed ; since the last removal has had discharge at times from this ear. Three years previously had a severe cold, Avas very deaf for a Aveek, and then gradually recovered ; but since that attack has been very THE MEMBRANA TYMPANI. 173 (leaf during a cold. Is at present suffering from a cold, and is so deaf as to require to be loudly spoken to close to liim. Right ear. — On examination, the surface appeared to be red, and at tlie posterior part there was a small depression, from which the dermoid layer had been eroded by ulceration. Wlien the tympanic cavity is distended, there is an outward bulging of the fibrous layers tlirongh the orifice in the dermis. Watcli heard Avhen in contact with the ear. Left ear. — Tlie dermoid membrane is white and thick, and dis- charo;e issues from its surface. Ilearino; distance half an inch. Treatment. — A discharge was kept up over each mastoid process, and small doses of blue pill were admistered ; by degrees the hear- ing slightly improved. Case III. Ulceration of tlie dermoid layer. Discharge of blood. — M. S. Chambers, aged 7, was admitted under my care at the St. George's and St. James's Dispensary, on January 18, 1850. JTistori/. — A year and a half ago, suffered from an attack of small- pox, from which she was very ill for six Aveeks. A few months after the attack, discharge suddenly issued from both ears, and has con- tinued ever since, being very offensive, and at times mixed with blood : has lately been also subject to itching in the ears, earache, pains in the forehead, and giddiness. On examining the right ear, its surface was observed to be red and tumefied, and there Avas an orifice, at the anterior part, through the whole of the laminjK. Left ear. — The dermis is of a deep red, and its central portion has been destroyed by ulceration : Avhen the tympanic cavity is distended Avith air, the fibrous layers bulge outwards. The treatment consisted in the administration of tonics ; in keep- ing up a discharge from the surfoce of the mastoid process ; and in the use of o;entle astrin of the mcmhrana tym- pani. — AV. AV., aged 50, a medical man, residing in London, con- sulted me, in 1852, on account of a long-standing discharge from the left ear, accompanied by deafness. IHstorij. — In early life, after repeated attacks of earache, a dis- charge flowed from the left ear, Avhich has not ceased for more than Fig. 65. The Fibrous Layers of the Membrana Tympani ulcerated over a small extent at its anterior part. The mucous membrane, remaining, forms a small cul-de-sac, seen externally. This illustration, from a preparation in my museum, gives an idea of the nature of the disease. a week or two at a time since that period. Lately there has been at times great deafness, producing extreme inconvenience, as the right ear has been useless during many years. L^pon syringing the left ear, a large quantity of offensive matter was removed, and the menibrana tympani became distinctly vi.a^(tti muscle arises from the fossa at the root of the internal pterygoid plate, from the adjacent bone, from the outer sur- face of the superior cartilaginous lip of the Eustachian tube, and from the membrane forming its outer wall ; and the fil)rcs from these several sources pass downwards, form a flat muscle Avhich winds round the hamular process of the sphenoid bone, to be in- serted into the aponeurosis of the palate, and into the ridge of the palate bone. The levator jjalati muscle arises from the inferior surface of the petrous bone, near the apex, and from the outer half of the under surface of the cartilaginous portion of the tube ; and the fibres de- scend in contact with the inner half of the under surface of the tube, and are inserted into the aponeurosis of the palate, some of the fibres uniting with those on the opposite side. The action of the tensor palati muscle, when it contracts, is to draw slightly outwards, and to keep on the stretch, the membrane ' De Aure Humana Trnetatus, 1735. THE EUSTACHIAN TUBE. 217 forming the outer wall of the Eustachian tube ; the action of the leva- tor palati muscle is to draw downwards and keep tense the lower wall of the tube : hence it will be seen that the combined action of the two muscles is to keep open the tube by drawing the membrane forming its outer wall apart from the cartilage forming its inner wall. As during the act of deglutition the tensor and levator palati muscles contract, it is evident that whenever that act is performed, the Eustachian tube must be opened ; and inasmuch as there is no apparatus by which the faucial orifice of the tube can be kept open, its lips must fall together, and the orifice close as soon as the muscles cease their action. During the few moments that the faucial muscles are brought into play in the process of deglutition, air can either enter or recede from the tympanic cavity, and thus be always of the same density as the outer air. The reasons why the Eustachian tube is closed, save during the momentary act of deglutition, are, first, that the tympanum may be generally a closed cavity, so that the sonorous vibrations reaching it may be concentrated upon the membrane of the fenestra rotunda ; and, second, that, as specially pointed out by Dr. Jago, sounds may be prevented entering the tym- panum from the fauces.^ PATHOLOGICAL OBSERVATIONS. Although from the preceding remarks there can remain little doubt « An examination of the faucial orifice of the Eustachian tube in other animals is corro- borative of the view above advanced. In inammalia the faucial orifice of the tube pre- sents much variety both in structure and form. In the animals I have dissected belonging to the class ruininantia, there is an entire absence of cartilage at the orifice of the tube, and the aperture is guarded by a thin fold of elastic membrane ; it is opened by the faucial muscles. In the cartiivora the cartilage is prominent, and forms a distinct rounded pro- jection. In the rodentia the orifice consists merely of a fissure in the mucous membrane of the fauces. In some of the mammalia the orifice is opened by the superior constrictor of the pharynx. In all the birds that I have been able to examine, the Eustachian tube was composed of two distinct portions, the membranous and the osseous j and no cartilage en- tered into their composition. The membranous portion consists of a sac, which is common to both ears, the upper extremity of which receives the two osseous tubes, and the lower extremity opens into the cavity of the fauces posterior to the aperture of the nares. The muscles which open the Eustachian tube in the bird are the internal pterygoid, or rather small muscles distinct from the pterygoid, but accessory to them. The common membra- nous tube is situated between the internal pterygoid muscles, and the lateral surfaces of the tube are in contact with, and firmly adherent to, the inner surface of these muscles or their accessories, so that when the fibres are drawn from the median line the walls of the tube are separated, and a free communication exists between the tympanic cavity and the pharynx. 218 ' THE DISEASES OF THE EAR. that the faucial orifice of the Eustachian tube is ordinarily closed, except during the act of deglutition, it is requisite to perfect hear- ing that the tube should be pervious, and that there should be a con- stant interchange of air in the cavity of the tympanum. If the Euf^tacliian tube becomes impervious, the air that was in the tym- panum at the time of the closure gradually disappears. It is not easy to decide whether it is absorbed, or whether by a kind of exos- mose it passes through the membrana tympani ; but whatever the cause, in a space of time, varying in different cases from a few hours to a day or two, there is no doubt that the air in the tympanic cavity becomes partially exhausted. The effect is to produce an increased concavity in the external surface of the membrana tym- pani ; a forcing inwards of the chain of ossicles ; pressure on the contents of the labyrinth ; and a very serious diminution of the hearing power. The morbid conditions of the Eustachian tube found in 1523 dis- sections were as follows : — Containing mucus, ........... 10 Containing mucus, lining membrane congested, ...... 2 Containing mucus, lining membrane thick, ....... 2 Lining membrane congested, .......... 5 Faucial portion, mucous membrane red and soft, ...... 2 Bands of adhesion connecting the walls, ..... .3 Stricture in osseous part, .......... 1 Stricture in cartilaginous part, ......... 2 Ver)' large, ............. 2 The causes of obstruction of the Eustachian tube may be thus classified. 1. At its faucial orifice ; a thickening or relaxation of the mucous membrane. 2. At its tympanic orifice ; thickening of the mucous membrane, or a deposit of fibrin. 3. In the middle ptcirt of the tube; a collection of mucus, a stric- ture of the osseous or cartilaginous portions, or membranous bands connecting the walls. 1. Obstruction of the Eustachian tube, at its faucial orifice takes place — {a.) From thickened mucous membrane. {h.) From relaxed mucous membrane. THE EUSTACHIAN TUBE. 219 (a.) OBSTRUCTION OF THE FAUCIAL ORIFICE FROM THICKENED MUCOUS MEMBRANE. In these cases there is usually enlargement of the tonsils, or hypertrophy of the mucous membrane of the nose and fauces. If the obstruction occurs in a young person, the mucous membrane of the nose is commonly so thick as to ofter some resistance to the easy passage of air, and to lead to the habit of breathing through the mouth ; a habit which at night is carried out to a marked degree, and the patient often snores loudly. Upon examining the fauces, the tonsils are sometimes found enlarged, and the fiiucial mucous membrane is thicker than natural. In the adult the latter condition is observed, but the tonsils are less frequently affected. The deaf- ness comes on usually rather rapidly, often subsequent to a cold, and, after remaining for a time, suddenly vanishes with a loud crack in the ear. This amelioration often accompanies the acts of yawn- ing, gargling, or other strong muscular effort of the fauces. The improved hearing which thus results rarely continues long ; some- times it lasts for a few hours, in others for a day : a variation which probably depends upon the intervals which elapse before the air dis- appears from the tympanic cavity. The amount of hearing depends upon the quantity of air in the tympanum. Sometimes the patient has to be loudly spoken to close to the ear ; at others a distinct voice is heard at the distance of two or three yards. There is fre- quently complaint of a sensation of weight or pressure in the ears, which often extends to the head, Avhen heaviness and great depres- sion of spirits are experienced. The latter symptom is very marked at times, but entirely vanishes with the removal of the obstruction. It possibly may originate from the pressure exerted upon the contents of the labyrinth by the forcing inwards of the membrana tympani and ossicles. A peculiar symptom sometimes met with in this affection, and for Avhich I am unable to account, is the improve- ment which takes place during the temporary position of the head on a pillow, or even if it be turned round and kept looking back- wards. Irritation is often complained of in the external meatus ; sometimes the dermis of the meatus becomes much congested, and eventually pours out a discharge ; and where it happens that the ir- ritation is still greater, a polypus forms, and there is a large quan- tity of mucus secreted. When a patient presents himself for advice, 220 THE DISEASES OF THE EAR. with obstruction of tlie Eiistacliian tube coexisting with polypus or the sympathetic discharge from the meatus, unless the case be most carefully examined the real disease is apt to be overlooked, and con- sidered to be an affection of the meatus only. On inspecting the membrana fi/mpani, it will be found very con- cave, of a dull leaden hue, and its surface of an unnatural, glassy aspect, the triangular spot being larger than natural. Sometimes the membrana tympani is so much drawn inwards as to approach the stapes, which is distinctly discernible through it ; in other cases, the membrana tympani is somewhat opaque, and its outer surface uneven and irregular. The exploration of the Eustachian tube. — The method of doing this is so important to a thorough examination, as to require to be treated in detail. In a paper read before the Medico-Chirurgical Society in 1853, I pointed out a simple mode of ascertaining whether the Eustachian tube was pervious, and one which, as a general rule, is successful, without having recourse to the catheter. It has already been shown, that during the act of deglutition, with the mouth and nose closed, a small quantity of air is passed through the Eustachian tubes into the tympanic cavities ; a process that is attended with a sensation of fulness in the ears. The entrance of air into the tympanum can be distinctly heard by means of an elastic tube about eighteen inches long, each end of which is tipped with ivory or ebony ; an instrument which I have named the Oto- scope. One end of it is to be inserted into the ear of the patient, and the other into that of the medical man, who must take care that no portion of the tube touches any ncighlioring body. When the patient swallows a little saliva, the mouth and nose being closed, if the Eustachian tube be pervious, at the moment that he feels a sensation of fulness in the ear, the surgeon will hear most distinctly a faint crackling sound, produced apparently by a slight movement of the membrana tympani. This crackling sound is that most usually heard ; but in some instances where the mucous membrane of the tympanum is thick, a gentle flapping sound will be detected in its place. If in a case of suspected obstruction of the Eusta- chian tube, the otoscope fail to reveal any sound during the act of deglutition ; if no sound be heard when the patient makes a forcible attempt at expiration with mouth and nose tightly closed ; and if the history of the case, the symptoms and appearances, agree with those already laid down as appertaining to obstruction of the Eusta- THE EUSTACHIAN TUBE. 221 cliian tube, I think the surgeon is justified in affirming that the tube is obstructed, and has no need to resort to the use of the Eustachian catheter. Doubtless, in many cases, a person is unable Fig. 77. The Otoscope. to force air into the tympanum, although the pervious condition of the Eustachian tube is shown by the test of the otoscope, and this may depend upon a peculiar arrangement of the lips of the tube which causes them to be pressed together by the compressed air. There are other cases also where the tube may be proved to be pervious by the patient forcing air into it during an attempt at expiration, although the act of deglutition with closed nostrils does not call forth any sound appreciable by the otoscope ; but it is rare indeed for a pervious tube to resist both of these tests. I have, however, met with such cases ; but, as their history, appearances, and symptoms have concurred in showing that no obstruction of the tube existed, it has not appeared necessary to introduce the catheter. In certain cases the membrana tympani may be seen to move during an attempt at expiration, even though no sound could be heard ; the patient, therefore, should always be asked whether he perceives any sensation in the ears during the above-named processes. Is the Eustachian catheter then useless as a means of diasnosis ? Notwithstanding its frequent use by surgeons in Germany and in France, I am disposed to think so. By paying attention to the points just laid down, it is my opinion that a case of obstruction of the Eustachian tube can always be diagnosed without the aid of the 222 THE DISEASES OF THE EAR. catheter. Respecting its use as a remedial agent, I shall speak hereafter. That the cause of the obstruction of the Eustachian tube at its faucial orifice is the thickening of the mucous membrane, is proved Fio. The Surgeon using the Otoscope. by actual dissection, by the coexistent thickening of the mucous membrane in other parts of the fiiuces, and by the results of the remedial measures adopted for its relief. An opinion formerly ob- tained a certain degree of credence in the medical profession, that enlarged tonsils frequently press upon and close tlie Eustachian tubes. There can be no doubt this opinion is erroneous. To con- vince himself that it is so, the surgeon has only to make an ex- amination of the relative position of the tonsil and of the trumpet- shaped extremity of the tube ; Mhen he will find the tonsil situated from an inch and a quarter to an inch and a half below the tube, and placed between the palato-glossus and palato-pharyngeus muscles, the latter muscle entirely separating the tonsil from the fube : he will also find the Eustachian tube close to the base of the skull, against the basilar process of the occipital bone, and surrounded by the tensor and levator palati muscles, the function of which is, as already shown, to open the tube. Repeated examinations have con- vinced me that even should the tonsil enlarge to its greatest possible THE EUSTACHIAN TUBE. 223 known extent, it never reaches the Eustachian tube ; for, together "with the enlargement of the tonsils, the palato-pharyngeus muscle also hypertrophies, and effectually separates the two organs. Nay, further, in the cases seen by me, where the tonsils have been the largest, there has been no deafness ; a fact which must also have been observed by other medical men. Often, in a case of obstructed Eustachian tube in one ear, the tonsil has been comparatively small on the deaf side ; while on the opposite side, Avhere tlierc has been no deafness, the tonsil has been large. There is no doubt that ob- struction from hypertrophy of the mucous membrane of the faucial orifice of the Eustachian tube may coexist with enlarged tonsils ; but the mere coexistence of two affections must not be confounded with cause and effect. TREATMENT OF OBSTRUCTION OF THE FAUCIAL ORIFICE OF THE EUSTACHIAN TUBE BY THICKENED MUCOUS MEMBRANE. Cases of this disease, when uncomplicated with any affection of the tympanum, ordinarily yield to the use of general remedies and applications to the fauces, without touching the outer ear. The object to be aimed at is the reduction of the congestion and hyper- trophy of the mucous membrane surrounding the orifice of the tube, so as to allow the muscles again to exercise their function of opening it ; and for this purpose considerable patience and perseverance are, doubtless, frequently required ; since in many strumous persons, especially if young, the tendency to congestion and thickening is very great. General Remedies. — The most efficient of these are abundant and active exercise in the open air, and warm clothing. Flannel should be worn next to the skin. In youths the flannel jacket, extending from the neck to the ribs, may not only be worn, but, in cold weather, in front, where the chest is exposed, a small additional piece of flan- nel may be worn suspended from the neck. The throat should not be wrapped up with handkerchiefs, comforters, boas, &c., as they only serve to weaken it, by keeping it Avarm for a certain time, and then, on their removal, leaving it exposed frequently to a colder air within doors than had prevailed without, thus bringing on relaxation of the mucous membrane. Where a single tie-handkerchief is worn within doors, no addition is needed on going out ; and where in 224 THE DISEASES OF THE EAR. cliilclrcn the throat is left bare •within the house, a small silk hand- kerchief, loosely tied, is all that is required without. I have been thus particular on these points, because experience frequently con- vinces me of their great importance. The surface of the body should be daily sponged or rubbed with a coarse towel that has been dipped in cold water, and then wrung out. As the children who suftcr from the affection under conside- ration have usually a languid circulation and deficient nervous energy, the towel bath appears to be a remedy advantageous in both respects. The towel should be very coarse, and only one part of the body should be rubbed at a time. The skin, especially that of the neck, throat, and spine, should be brought to a ruddy glow. This bath may be used either in the morning or the evening, but once daily is sufficient. If the patient be so very delicate that he cannot well bear the slight shock produced by the cold towel, tepid water may be used. In addition to this bath, indeed to supersede it, especially in youths of from fourteen to sixteen, by whom it is not likely to be carried out effectually, the tepid or cold plunge-bath may be resorted to. AVhen it can be practised, sea-bathing should not be neglected; but in all cases of entire immersion it is advisable to wear an oil-skin cap, to keep the head dry: and this, not because the application of water to the head is objectionable, but because there is so great a difficulty in perfectly drying the hair, and the slow evaporation from it is often decidedly injurious. Plunging into a fresh-water river in warm Aveather is not prejudicial. In the treatment of the cases in question, too much stress cannot be laid upon the necessity of exercise, bracing air, and cold bathing. I have known them to overcome the most obstinate cases of obstruc- tion of the faucial orifice of the Eustachian tubes, where all local remedies and medicines had given slight or only temporary relief. Care should also be taken as to the diet of the patient : pastry, sweets, fat, &c., should be avoided ; vegetables may be sparingly partaken of; and the principal food should be bread, especially that containing the bran, meat, and light puddings, as rice, sago, &c. Children should not be overworked in their studies, should retire early, and their sleeping-rooms should be airy and well ventilated (it is a good plan to leave the bedroom door ajar during the whole of the night) ; and, above all, it is important that the head should be kept above the bedclothes. To overcome the very prevalent habit of breathing through the THE EUSTACHIAN TUBE. 225 mouth, whereby the cokl air keeps up a constant irritation of the faucial mucous membrane, the patient shoukl be directed to sit down quietly for a certain time daily, and practise the habit of nasal respiration. Although it may at first seem difficult, the mucous membrane of the nose soon yields, and the air passes freely.^ Medicines. — All medicines that impart tone to the system, may in turn be resorted to. Cod-liver oil, iron in various forms, iodide of iron, iodide of potassium, creasote, and the mineral acids and vegetable bitters, will be found useful. Local Treatment. — The most efficient local application is undoubt- edly the nitrate of silver, which may generally be used in a solid form. Messrs. Weiss have made for me a caustic holder, the end of which is capable of being turned at such an angle, that the caustic may be passed behind the soft palate, and applied to the mucous membrane of the orifice of the tube, as well as to that of the fauces. Should the tonsils be enlarged, the solid nitratt of silver may be rubbed over their surface, and over that of the faucial mucous membrane, about once a week ; and it should produce con- siderable irritation and a copious flow of mucus. Stimulating gargles are also to be used ; those combining acids and astringents are of service. Iced or cold water is often beneficial ; and in order to insure the application of the cold Avater to the orifices of the tubes, as well as to improve the condition of the mucous membrane of the nares, the water may be drawn up through the nose, and passed out by the mouth. "When there is much congestion of the faucial raucous membrane, a leech or two, a stimulating liniment, or a vesicating paper, may be applied over the region of the tonsils. TJie use of the Eustachian catheter. — It Avas, and is even noWy the custom of some surgeons to pass the Eustachian catheter re- peatedly in cases of obstruction of the Euotachian tube. Now^ what is the effect of this procedure ? If the mucous membrane be not much thickened, air is blown into the tympanic cavity, and the power of hearing is improved. As soon, however, as the catheter is withdrawn, the tube again closes, and its muscles have not the power to reopen it ; while the air which has been forced into the cavity soon disappears, and the deafness returns. The patient again seeks relief from the same process and with the same result ; ' Many years ago I pointed out the peculiar erectile tissue of which the nasal mucous membrane is composed, not only in man, but in most mammalia ; this tissue renders it a most eflBcient natural "respirator.'" 15 226 THE DISEASES OF THE EAR. for if the mucous membrane is allowed to remain in its existing state, no permanent relief is to be hoped for ; on the contrary, the repeated use of the catheter tends rather to increase than diminish \he congested state of the membrane. Under certain circum- stances, however, the Eustachian catheter is of great value. The judicious course respecting it, is to use the above-named plans for the purpose of reducing the hypertrophy of the mucous membrane, which will, in the majority of cases, eflFect the cure of the disease. If, after pursuing these measures for ten days or a fortnight, no amelioration ensues, the Eustachian catheter may be introduced and air blown through the tube into the tympanum ; an operation which may at times possibly facilitate a cure by the removal of mucus from the tube, or by liberating the lips of the faucial orifice. Seve- ral days, however, should elapse before the operation, if required, is repeated, and this will seldom be the case. The mode of applying the Eustachian catheter. — It has been already stated that the orifice of the Eustachian tube is posterior and external to the posterior aperture of the inferior nasal meatus. The catheter used by me is not quite so large as an ordinary crow- quill ; and as the outer part of the Eustachian tube is oval, it has been recently suggested by me that the extremity of the catheter should be of the same shape. The end of the catheter taken hold of by the surgeon should be rather larger than that which is to enter the tube, in order that the end of the explorer, or the nozzle of a syringe, may be fixed in it. This end having a ring on the side opposite to the concavity of the curved end, is to be taken in the right hand of the surgeon, the patient being seated in the chair before him, and then the instrument, Avith the point downwards, is to be made to glide backwards, by the side of the septum nasi, until the curved end reaches the cavity of the fauces, when it is to be pressed backwards against the mucous membrane of the posterior part of the fauces. It is next to be drawn slightly forwards, and then rotated outwards, so that the extremity may turn upwards and catch the orifice of the Eustachian tube, which can be distinctly felt, and will prevent the further rotation of the instrument. The cathe- ter is now to be pressed slightly outwards and backwards, when the surgeon will feel it to be embraced by the tube. For the purpose of securing the instrument, a frontlet bandage, with a pair of for- ceps attached, has been used ; but it may be dispensed with in all ordinary cases : for the surgeon has only to transfer the catheter to THE EUSTACHIAN TUBE. 227 his left hand, and while holding it lightly, so as not to cause pain to the patient (as the use of the frontlet invariably does), insert into the dilated end of that instrument the small end of the explorer or of the syringe. The explorer, which in my hands has entirely super- FiG. 79. The Explorer, and the Eustachian Catheter into which it fits. seded the use of the air-press, consists of an elastic tube, about eighteeen inches long, one end of which has a flat mouth-piece of ivory, with one or two deep incisions upon it, to enable it to be easily held by the incisor teeth of the operator, Avhile the other end has a small portion of steel tubing attached to it, which fits accu- rately into the further end of the catheter. "When the catheter has been properly fixed, as directed in the tube, and held there by the left hand of the surgeon, one end of the explorer is to be placed in his mouth, and the other in the catheter, and held there also by the left hand. With his right hand, thus left at liberty, the surgeon is now to take the otoscope and introduce one end of it into the car of the patient, who may hold it there, the other end being held by the surgeon in his own ear ; or the tube may be made so light as to remain there without being held, leaving the operator's right hand still free. The medical man next proceeds to blow air gently through the explorer, at the same time that he listens through the otoscope to ascertain whether the air enters the ear, and if it does, what is the peculiar sound it produces. When the tympanum is unobstructed by mucus, the air is heard to pass in a stream against the inner surface of the membrana tympani, but when mucus is present, a peculiar gurgling is heard ; and if the mucous membrane itself is thickened, a peculiar squeak or bubbling is also perceptible. It is 228 THE DISEASES OF THE EAR. not advisable to blow with force into the ear, but rather to make a few gentle successive puffs, attentively listening during each, to detect the kind of sound that may be heard in the tympanum. Fig. 80. The Surgeon using the Eustachian Catheter and the Explorer. Sometimes no air enters, the mucous membrane being too thick to allow it to pass ; and, under such circumstances, it is unwise to attempt to force the air into the tympanum. Great mischief has, indeed, frequently resulted from such a proceeding; the mucous membrane having been lacerated, and the air been driven into the submucous tissue, causing extensive emphysema. Nay, still more serious results have occurred, the patient having been killed in- stantaneously, perhaps through the effusion of air through the fenestra rotunda (the membrane having been lacerated) into the labyrinth, and the shock upon the nervous system causing instant death. Xor need it be a source of surprise that the effusion of air into the labyrinth should prove fatal, since even the forcible disten- sion of the tympanum, while blowing the nose frequently, produces giddiness by pressure upon the labyrinth. Tlie excmon of the tonsils. — On the supposition that the tonsil, when enlarged, pressed against and closed the faucial orifice of the Eustachian tube, the operation for excision, or partial excision, of the tonsils, has long been practised for the relief of deafness. Al- THE EUSTACHIAN TUBE. 229 though, as already shown, the tonsil, however hypertrophied, cannot cause occlusion of the Eustachian tuhe, still the removal of a portion, in cases where it is much enlarged, is sometimes of service by dimin- ishing the conjiestion of the mucous membrane at the orifice of the tube ; and it perhaps also operates beneficially by allowing the muscles of the tube to act more freely. This operation is, however, very rarely required ; and the best rule to follow is never to excise a portion of the tonsil, which appears to have important functions, independent of the fauces, unless it evidently interferes with the general health of the patient, or unless the obstruction of the Eustachian tube resists the other measures already indicated. CASES OF THE OBSTRUCTION OF THE EUSTACHIAN TUBE BY THICK- ENED MUCOUS MEMBRANE, AT ITS FAUCIAL ORIFICE. Case I. — Master M. J., aged 15, was brought to consult me, on December 4, 1852, on account of a very serious diminution of the hearing power, in both ears. He Avas in tolerable health, but pale. About a year previously, after suffering from a bad cold, he became dull of hearing, and since then has been able to hear only when spoken to in a loud voice, within the distance of a yard or two. Occasionally he has felt a sensation as of something bursting in the ears, which has been followed by slight, but only temporary relief. Upon examination, the mucous membrane of the fauces was found very thick and red, and both tonsils greatly enlarged. The right ear. — Watch heard only when in contact with the ear ; the membrana tympani being opaque, of a leaden hue, and more concave externall}'' than natural, while, instead of the usual triangular bright spot, tAvo bright spots Avere perceptible, showing that the membrane was de- prived of its ordinary evenness of surface. Upon listening with the otoscope while the patient swallowed, the mouth and nose being closed, and while he tried to force air into the tympanum, no sound was heard. The left ear was in a very similar state to the right ; the watch, however, could be heard at a distance of two inches from the ear. Feeling assured from the history of the case, the symp- toms, the condition of the throat, the appearances of the ear, and the negative results following the use of the otoscope, that the Eustachian tube Avas closed at the faucial orifice, especially as there Avas no indication of disease in the tympanum, Avhich might lead to 230 THE DISEASES OF THE EAR. the supposition of tlie tympanic orifice being affected, I did not use the Eustacliian catlieter, but proceeded at once to apply a solution of nitrate of silver to the mucous membrane of the fauces, and to the orifices of the Eustachian tubes. Three grains of the sulphate of iron -were given daily in combination with ten grains of sulphate of magnesia, and slight counter-irritation was kept up over the region of the tonsils. As a remedial measure, the catheter was not resorted to, as it "Nvas evident that the hypertrophy of the mucous membrane had slowly come on, and it was not probable that it could be other- wise than slowly improved. The first effect of the treatment was a slight improvement of the hearing, although the tube remained impervious ; an improvement which probably depended upon the diminution of the congestion in the mucous membrane of the tym- panum. By the end of January, the hearing power of the right ear had greatly improved ; and in the middle of February, the air passed freely through the Eustachian tubes during the act of deglu- tition, and the patient heard quite well again. Case II. OhistriLction at the faucial orifice for two montJis. — W. "W., Esq., aged 52, being strong and in good health, consulted me on July 26, 185-3. He stated that two months previously, after a bad cold, he became slowly deaf in both ears, so as to require per- sons to speak loudly to him Avithin the distance of a yard. On the 24th, after yawning, he suddenly experienced a crack in the left car, and as suddenly heard well ; but this improvement only lasted for a day, and then the deafness slowly returned. He has had three similar attacks during the last ten years, but in about a month's time the hearing usually returned after a cracking sound in the ears. At times, on throwing the head back, he has found the hear- ing power in the right ear much improved. On examination^ the mucous membrane of the fauces was red and hypcrtrophied. lUglit ear. — Hearing distance three inches ; the meatus was red and hypcrtrophied, the mcmhrana tympani more concave than natu- ral, its surface uneven, and instead of the single triangular bright spot, there were two smaller spots. Euatachian tube. — The otoscope did not detect any air entering the tympanic cavity during tlic process of deglutition, or upon an attempt at a forci])le expiration with closed nostrils. Left ear. — Watcli heard only when in contact with the ear ; the mcmbrana tympani was in a similar state to that of the right ear, THE EUSTACHIAN TUBE. 231 and the long process of the incus coukl be seen through it. The Eustachian tube was impervious. By the use of stimuLiting gargles and a liniment over the ears and throat, the patient entirely recovered in the course of a fort- night. Case III. Ohstruetion of the faucial orifice : catarrh from meatus : tonnih very large : cure without excision. — Master B., aged 16, was brought to consult me in August, 1850. His general health was not very good, and he was subject to glandular enlargements. History. — The right ear has always been slightly dull,, and for two or three years it has been worse. The left ear lately has also become so dull, that he requires to be spoken to distinctly within the distance of a yard from the head. Has had several attacks of earache; after Avhich, and also after a cold, the deafness is increased. Has had discharge from each ear on several occasions, and complains of a singing in them. When asleep he makes a loud snoring sound, and he always breathes through the nose. At times has had a cracking sound in the ears, which has been followed by a tempo- rary improvement. On examination, the tonsils were found to be so greatly enlarged as nearly to touch the median line, while the mucous membrane of the fauces and of the nose was much thicker than natural. Right ear. — Hearing distance half an inch ; membrana tympani concave ; bright spot somewhat dull. Eustachian tube impervious. Left ear. — Hearing distance two inches ; the bright spot of the membrana tympani subdivided. Eustachian tube obstructed. As the tonsils in this case were so much larger than natural, and as they apparently interfered Avith the respiration of the patient, and perhaps with his health, it was thought that the removal of a portion of one or both might be attended with benefit : but the pa- tient's friends so strongly objected to the operation that it was not performed. The treatment consisted in the application of solid nitrate of silver to the fauces ; in the use of an astringent gargle Avith counter-irritants over the ears and throat ; in the administra- tion of tonic medicines ; and in careful diet, with abundant exercise in the open air. On August 21st, a crack took place in the left ear, when he heard perfectly for a short time. After this date, a suc- cession of cracks was heard in each ear, and at last the hearing power entirely returned and remained perfect, except during a cold, the effects of which, however, soon disappeared. 232 THE DISEASES OF THE EAR. CaseW. Obstruction from the mucous membrane of the fauces; polypus in meatus externus ; removal by operation; cure. — H. W., Esq., aged 19, was sent to me by Mr. White Cooper, in February, 1854, on account of a consitlerable diminution of the power of hear- ing, and of a discharge from the right ear. Ilis health was not very good, and he was subject to enlarged cervical glands. The history of the case was, that about two years ago he found himself becoming gradually dull of hearing. After this dulness had remained some months, accompanied by a feeling of fulness in the ears, a discharge took place from the right ear, the quantity of which has lately con- siderably increased. On examination, the mucous membrane of the fauces was observed to be red and thick. Right ear. — The watch heard only when in contact ; a raspberry polypus, the size of a small pea, Avas seen to fill the meatus, close to the membrana tympani. Left ear. — Hearing distance six inches ; membrana tympani opaque, and calcareous in parts. Each Eustachian tube was imper- vious to air. The treatment consisted in the removal of the polypus by means of the lever-ring forceps. The membrana tympani was then observed to be white. Astringent and acid gargles were used ; slight counter-irritation was kept up over the cars and the region of the fauces ; tonics were administered ; and daily sponging with cold water was enjoined. In the course of a week a crack took place in the right ear, followed by immediate great improvement of the hearing ; this was succeeded by a crack in the left ear, and a perfect restoration. The discharge also wholly disappeared. On seeing this patient several months afterwards, I found his hearing perfect, and there had been no return of the discharge. I have said that the use of the Eustachian catheter is rarely re- quired, because the state of the mucous membrane generally so much improves by means of the other remedies. In the following case, however, wliere there was an additional cause of impediment besides the thickened mucous membrane, the catheter was used with advan- tage. Case V. Impervious condition of the tube from hypertrophy of the mucous membrane at the faucial orifice ; fissure of the palate ; ca- theter used ivith advantage. — Dr. P., a medical man, aged 43, con- sulted me in 1853, on account of deafness. History. — Several j'ears previously he had a disease of the palate, which terminated in the loss of a considerable portion of the palatal THE EUSTACHIAN TUBE. 233 processes of tlie superior maxillary and palatal bones, and caused a large fissure. During tlie last two or three years he has suffered from attacks of deafness during a cold, which, after continuing for some weeks, have disappeared. On cvamination, the mucous mem- brane of the fauces was found to be red and mucli thicker than natu- ral. Towards the posterior part of the palate was a large fissure, exposing the trumpet-shaped extremity of the Eustachian tube ; the mucous membrane of which was much swollen. Each membrana tympani was of a leaden hue and very concave ; and there was an appearance of redness beyond each, as if the mucous meml)rane were congested. The patient had to be spoken to distinctly within the distance of a yard. The Eustachian tubes were impervious. Treatment. — A solution of nitrate of silver (5ij @ Sj) was applied to the mucous membrane of the fauces and to the orifices of the tubes ; an astringent gargle was ordered, and gentle counter-irrita- tion over the throat. This treatment produced a slight improve- ment ; but as the deafness soon returned, as the patient Avas espe- cially anxious to hear, and as it appeared probable that the muscles of the tube were partially disabled from performing their function, I passed the Eustachian catheter, and, by means of the explorer, blew air into the tympanic cavities. The good effect was instantaneous, and the patient heard well. The improvement, however, lasted for only about twelve hours, when the deafness gradually returned. At the desire of the patient I passed the catheter on several occasions, while other treatment was being followed. After each operation the hearing improved for about the same space of time ; ultimately the condition of the mucous membrane was so much improved as to allow the muscles to open the tubes, and a cure resulted. In some cases after the Eustachian tube has been obstructed for a long time, the patient may almost wholly lose the power of hear- ing. These cases, as will be seen by the following instance, are by no means to be despaired of. Case VI. Obstruction by tliichened mucous membrane of the faucial orifice ; duration of many years ; great and jyrolonged hard- ness of hearing ; cure. — Miss J. A. 0., aged 12, was brought to me from Manchester, on the 16th April, 1853. She was strong, but rather pale. The history of the deafness Avas, that during several years she had been dull of hearing during a cold ; on the disap- pearance of which, the power of hearing partially returned, so that she could hear without much difficulty. For some months the deaf- 234 THE DISEASES OF THE EAR. ness has been so much •worse, that she cannot hear unless spoken to in a loud voice into the left ear, the right being useless. On examination, the mucous membrane of the fi\uces Avas found to be red, thick, and spongy, but the tonsils -were not larger than natural. The mucous membrane of the nose was very thick and red ; and respiration was usuall}' carried on by means of the mouth. Hifjlit ear. — Watch heard on pressure, but indistinctly: membrana tympani concave, surface uneven ; and on that surface three irre- gular-shaped bright spots -were seen. Eustachian tube impervious. Left ear. — "Watch heard -when pressed; membrana tympani and Eustachian tube the same as in the opposite ear. Treatment. — The solid nitrate of silver was directed to be applied to the mucous membrane of the fauces once a week ; counter-irritation over the ears, and a leech or two at times over the region of the fauces ; the one-thirtieth of a grain of the bichloride of mercury twice daily, and a warm bath once a week : occasionally an emetic was also given. She returned to Manchester, and on the 28th of May her father wrote to me, saying that she was " so much better that she can keep up a conversation across the table."' The child had a relapse in the following January, but a repetition of the treatment again restored her to perfect hearing. It is not, hoAvever, only in long-standing cases of obstruction of the Eustachian tube that the deafness is very considerable ; in weak persons almost total deafness may come on in a few hours. A well- marked case of the kind has occurred to me while writing the present chapter. Case VII. Sudden ohstruction of each Eustachian tube from con- gestion and tJiickening of the mucous membrane of the fauces, jrro- ducing total deafness in a few hours ; cure. — Dr. B., on the 24th January, 1855, called to ask me to see his wife, of whom he gave the following Idstory. For several months she has been much out of health, and confined to her room ; but has never suifered from any deafness or dise:xse of the ear. On the night of the 20th instant she awoke, complaining of a loud singing in her ears ; and when spoken to, it was found that she was so deaf as not to be able to comprehend what was said, although addressed very loudly. If possible, this deafness increased, so that on the 22d no sounds were heard, and all communication had to take place in writing. On examination, on the 24th, I found that the deafness was complete ; each membrana tympani was very THE EUSTACHIAN TUBE. 235 concave and dull ; the mucous membrane of the fauces "was very red and thick, the tonsils and uvula much swollen. Each Eustachian tube was impervious. Upon inquiry I learnt that accidentally a part of the window had been left open during the night. The treat)nent recommended was the application of the solid nitrate of silver to the fauces and the orifices of the Eustachian tubes. This was done freely about eleven o'clock on the 2Gth. Dr. B. returned home about two hours after, and found the hearing so improved that he carried on a conversation with his Avife in a loud voice. I miirht add to the above a laro-e number of cases in which the treatment was quite successful, but will merely give the leading particulars of another. Case VIII. — H. L., Esq., aged 28, consulted me on June 25, 1853. Has suffered for several months from sore throat, conse- quent upon an attack of secondary syphilis : for two months has complained of deafness in both ears, so as not to hear any except a loud voice. The deafness is accompanied by constant singing, which is increased when the head is on the pillow, and it varies nuich. On one occasion, after gargling the throat, heard much better with the ri/.—^Yhen the skull was sawn' through, pus flowed trom within the dura mater; and upon examination it was found to come from an abscess which occupied the whole of the upper part of the riaht cerebral hemisphere. The substance of the surrounding brain was healthy. The dura mater above the part cut off by the saw presented a patch of coagulable lymph, about the size of a four- penny piece; lymph was also effused on the surface of the dura mater, covering the petrous bone, and a portion of it was detached from the bone. Upon dissection of the ear, the membrana tympani was absent; the tympanic mucous membrane, and that of the mastoid cells, was thick and soft, and covered by a large quantity of caseous, scrofulous matter. The upper tympanic wall was of a dark color, extremely thin, and perforated by numerous blood- ve^^sels. The dura mater covering the upper part of the petrous bone an->*^ ^ O 3 3 .ti o O T3 -2 rt S) o 'O a ci ^ c ,> ^ ^ 3 ^ '■O o. ■^ •P-^ o •< ■^"s "^ t-. rt ii'TJ a -a o B 3 rt 1 and lit ma ebri, a s, c 5^ S .-: 3 o n rt 3 rt a. i'~2 c >, •- o t-. -^ u _ i t ^'i-i-^i s E'o tc 3 3 rt '5 3 5 3 P '^ '^'^ >^ rT" ■t; ^ "t; vh rr- So- '-^ o CJ^O B 3 5 3 "^ — 3 5;S£Crt_=: C~ 3 ^ =- c o O "rt o II rt o o o tffl §5 O r3 3 ^ c- s o - o o ^ - c X niddl rous a sn later rifice 'S "c 'C -3 -3 — ^" c c; ^ rt " " ji; "^c-rt = s rt s-s 3 O r S rt -^ t; rt c = ""o a> o •'" .„.- rt ^ 73 'T3 "T ,^3 ►J Q > 3 to rt O -" 3 rt 2 cj « v; 3 > O a; O O a; "5 d tc o 2 -r 05 3 t, t. rt tt rt <*. " o E ° tc "^ '^ rt 2 rt = .r P o 5 o S S rt^^ to ■^ o ." CiT3 « rt C ; s rt s rt S5I3 E 5 E to -^3 _ ^ -3 5 fcC^ C3 o^ tH *- -^ 3 »-• _C -J, c^-S ° :r 3 „ -^ E c. S ^ -^ ~ rt " r- •" ^.2 _ .-• 3 -a rt ::> 2 .^ C' rt ^ 3-^ rt fe •5 'C =-- _e &.." C •"" o OJ ^ 3 ?^ o — rt > rt o fO a) ;- IS m 3 C 'sl 3 3 -a ^1 2i 2 "o t4 o 1 1 «»- o o _ 3 CO 2 o O O <-• CJ O CO O CO 9J J c: c3 CO .^ 3 .S 0_cj CO ^ 2 to "^ — .. (5 a> to 3-^3 c S S3 m 3 'S »- SS J 3 ^ a ll CO 3 ,3 c-C .2 3 a " S 3 'S M tr' ^^ ^ "a to 3 — 2 'r* . — ^ ■"" 2? S ci c±f 1^ 5 fco C3 .2^ t— ;: " 2 3 S:; 1^ S 0^3 "tc 2 .S "^ "sB S +J ^^ t- y: '•^ oC CO CO 3 C Ji to ■^ 'co •^ t« c3 to G. = '^ V2 • — "tr^ o m 05 ^ , to 3 3 CO ST 3 to „^ O Q^ u Si > ciT en CO 9 -if -3 — . CO 3 IS 3 3 re to . 3 3 0) .2 -^ ■^ 'to C 3 cS 3 Q. ^ s <^ ' S-i o s o _ t- cj 3 = 2 *^ to -3 __ ^ 3 cS ;C 2j a 3 3 iT CO s >> aj -2 < o a .2 =0 s .s 5 IS M ^ = O o 3 S3 a C3 M ^ t- o <^ 3 -3 O _3 3 *-3 2 "S "3 9 c a, •- o to .S Cm to ->^ to 3 3 CD S So 3 CO C3 T3 i •5 «« ft. 'c3 ft. o ■5 -^ S .:2 •5 bo fti p** '' ■3 to 3 -• 3 >. S-i 3 ci 3 t- -:: 3 rt ^ *- Ol CS 0) 0) OP a o o o r- -■ "^ c^^ c:2 S c ee to W ■< ^ °9 jj 9.S «o •I *- o -«N OJ C5 (M ■3 --I 'i* e^i e-< CO < 366 THE DISEASES OF THE EAR. It is true that many persons live long, having had, during the Avhole of life, a discharge from the ear -without any disease of the bone : others live many years •with a discharge, but at death the bone and dura mater are found affected, and might under many cir- cumstances have assumed an active form of disease, ending in death. It is important, therefore, to be able to form an opinion respecting cases of the kind. To do this, it is first necessary to decide upon the source of the discharge. If it arises from the dermoid meatus, the membrana tympani being entire, there is, as before stated, most probably irritation in the tympanic cavity or mastoid cells, of which irritation the discharge is the symptom. Unless there •were simply some eczematous state of the meatus to account for the discharge, and unless the hearing power Avere perfect, such a case should be looked upon ■with suspicion, especially if attended ■with any symptoms of brain or cerebral irritation. Again, if the discharge issues from the tympanic cavity through a small or a valvular opening, and it is requisite to blo^w the nose forcibly to clear out the tympanum, there probably is, or ■will be, some affection of the bone, from the accumulation of the discharge. If there is a large orifice in the membrana tympani, or that membrane is absent; if there is no ulcer- ation of the mucous membrane of the tympanum ; if there is some power of hearing remaining ; and if by pressing and tapping the region round the ear, no pain is felt ; and if there are no other symp- toms of disease in the ear or head, I think it may be assumed that there is no disease of the bone ; and that by attention to daily syringing, and the other plans alluded to when speaking of the treatment of these affections of the ear, there is a fair prospect of the disease remaining confined to the mucous membrane of the ear. On the other hand, it becomes a duty to state that any negligence on the part of the patient, by which the discharge should be allowed to collect so as to fill up the orifice in the membrana tympani — a blow on the ear, an attack of fever, or any severe illness, might cause an irritation in the ear, which, if unattended to, might advance to the bone. CHAPTER XV. THE DISEASES OF THE NERVOUS APPARATUS OF THE EAR, PRO- DUCING WHAT IS USUALLY CALLED "NERVOUS DEAFNESS." . DISEASES IN WHICH THE EAR ALONE IS AFFECTED : — 1. FROM COXCUSSIOX — THREE MODES — BLOWS ON THE EAR — LOUD SOUNDS — FALLS. 2. FROM THE APPLICATION OF COLD — COLD AIR — COLD WATER. 3. FROM THE EFFECT OF MORBID POISONS — RHEU- MATIC FEVER — TTPHUS FEVER SCARLET FEVER — MUMPS — GOUT. h. DISEASES IN WHICH THE BRAIN AS WELL AS THE EAR IS AFFECTED : — 1. MENTAL EXCITEMENT OVER-STUDV — SORROW. 2. BODILY DEBILITY WANT OF SLEEP — ACCOUCHEMEXTS — OVER-EXHAUSTION IN HOT CLIMATES — FASTING — NEURALGIA. The nervous apparatus whicli receives the sonorous undulations from the tympanum, and conveys them to the brain — one of the most delicate structures in the human body — is liable to many func- tional and organic derangements.' As some cases of deafness depen- dent upon the derangement of the nervous apparatus connected with the organ of hearing, appear to be caused by the condition of the brain generally, or of that part in intimate relation with the acoustic nerve, it has seemed desirable to divide the nervous diseases of the ear into two classes : to the first of which belong those cases where the special nervous apparatus of the organ is alone affected ; to the second., those where the brain conjointly with the ear, seems to be injured. The first class may be subdivided into diseases arising from — (1.) Concussion. (2.) The application of cold'. (3.) Various poisons : as that of typhus, scarlet, or rheumatic fevers, of measles and mumps, of gout, of an accumulation of bile in the blood, and of quinine in large doses. And the secondanto diseases arising from — ' As I have nothing to add to the descriptions usually given of the anatomy of the laby- rinth, I have not entered upon the subject. 368 THE DISEASES OF THE EAR. (1.) Excess of mental excitement. (2.) Physical debility. [a.) DISEASES IN AVIIICH THE EAR ALONE IS AFFECTED. This section will be occupied with a revicAv of the various kinds of disease comprehended under the first of the above classes, all of which are usually accompanied by more or less of congestion. (1.) I>chHit>j of the JVervous Apparatus of the Ear 2)rodueed hy Concussion. Concussion may arise in three ways ; either from a blow on the ear, or from the effect of loud sounds, or from a jar of the whole frame. Affections of the nervous apparatus of the ear, as the result of blows on the external organs, are not very common, !?ince, as a general rule, the membrana tympani gives way and is ruptured, and consequently the shock on the drum is so far modified in its effect on the ossicles and the fenestra ovalis, that the contents of the labyrinth receive no greater injury than that which causes a slight dulness of hearing for a few days. Cases of more permanent injury to the acoustic nervous apparatus do, however, sometimes happen from the effects of a blow on the ear, as in the following case. Injury to the nervous apparatus of the ear, produced by a hloiv on that organ. — A physician in London, while playing with his little chil- dren, suddenly brought his right ear in contact with the head of one of them, causing a rather severe concussion on that side of his own head. The concussion was instantly followed by a singing in the ears. I saw the patient soon after the accident, but could detect no unnatural appearance in the membrana tymj»ani ; and on carefully testing the hearing power by the watch, there appeared to be no dulness of hearing. This physician has been seen by me from time to time since the accident, and he tells me the singing remains as it was on the day the concussion took place. The nervous apparatus of the ear is frequently injured also from the effect of a general concussion of the body, in which case the hearing power is often entirely destroyed. The well known in- NERVOUS DEAFNESS. 369 stance of the late Dr. Kitto, wlio Avas rendered wholly deaf by a fall from the top of a house when a boy, may be noticed in illustra- tion, and some others follow which have fallen under my own obser- vation. Fatal deafness in the rigid ear, and partial deafness in the left, folloiving a fall from a horse. — The Rev. R. F., aged 53. During many years his hearing has been dull during a cold. Five years before seeing me, he had a fall from his horse, and the fall was fol- lowed by a discharge of blood from the right ear for the space of tAvo days, and subsequently of matter. For some days after the accident, the air whistled out of his right ear whenever the nose was blown. Since the accident, the right ear has been entirely useless, and the left so deaf that he has to be loudly addressed within a yard of that ear. There has also remained a constant singing noise in the head. On inspection, the hearing of the 7'ight car was found to have been wholly destroyed, and the membrana tympani pre- sented an orifice, the margins of Avhich were opaque and uneven. Left ear. — The membrana tympani was dull on its surface, and in parts calcareous. In some instances, slight amelioration of the deafness following the accident takes place, as in the next case. Total deafness in the right ear folJoioing a fall from a phaeton ; gradual improvement. — The Rev. J. L., aged 35, had a deafness in the right ear during a cold four years ago. In the same year he fell from a phaeton, and was unconscious for some days. When he recovered his sensibility, he found that there was a hissing sound,, like that from a teakettle, in the right ear, which Avas completely deaf. During two years, however, subsequent to the accident, the power of hearing gradually improved, so that the patient is able to hear a loud voice Avith that ear. The noises still continue, and are aggravated by wine, or by bodily or mental fatigue ; when writing or studying, these noises become overpoAvering, but in the morning are much lessened. On inspecting the right ear, the air is distinctly heard by me to enter the tympanic caA'ity, but the patient experi- ences no sensation in the ear Avhen it enters. A loud ticking watch is heard. When spoken to through a trumpet, loudly and slowly, the voice is heard, but not till a second or two after the Avord has been uttered. The membrana tympani Avas opaque. The violent shock communicated to the nervous system of the ear (most probably through the medium of the membrana fenestras ro- 24 370 THE DISEASES OF THE EAR. tiindio) in the act of coughing, sometimes produces deafness ; in- deed, in some cases, hooping-cough seems rather to cause deafness by this means than by the agency of poison. Nervous system of the ear injured by violent coughing. — Mrs. A. consulted me in 1851, and stated that a week previous to her visit, directly after coughing, she experienced a pain in the left ear, which lasted for two hours, together with a loud singing noise which has never ceased. She complains of an unpleasant sensation as if sounds passed through the ear, and is troubled with a sense of giddi- ness, and a feeling of confusion in the head. Every step she takes sounds like the beating of a drum. Tlie mcmbrana tympani was fallen in, and its surface dull. The watch was heard only when in contact with the ear. Means having been used to diminish the con- gestion of the nervous apparatus of the ear, the distressing symp- toms of nervousness and giddiness disappeared, but the singing sounds remained. The concussion upon the nervous system of the ear resulting from loud sounds is a very common cause of deafness. In a previous part of this volume, when speaking of the functions of the ossicles and muscles of the tympanum, it was shoAvn tliat the one use of the tensor tympani muscle is to render tense the membrane of the fenestra rotunda, as well as that of the larger membrane ; and in this tense condition the membrane of the fenestra rotunda is thrown into vibratory movements of much less extent than when it is in a relaxed state. When a loud sound is anticipated, the tensor tym- pani muscle draws the membrana tympani and the membrana fenes- trae rotundne tense ; so that, when the approach of a loud sound is expected, it rarely injures the ear. On the contrary, however, when both membranes are comparatively lax, the same sounds throw them into very extended vibrations, and tlic fluid in the cochlea by the magnified movements of the membrana fenestrjx: rotundi\j is so con- cussed as to injure, and often most seriously, the expansion of the auditory nerve in the laliyrinth. Injury to the nervous apparatus of the ear may be produced by a variety of sounds. Cases Jiave been seen by me in which a cannon- ade at laud or sea, or the firing a single cannon, has produced the injury; and others have occurred where an explosion of gas, thunder, a pistol shot, or even loud shouting near the ear, have resulted in the same effect ; but the most common cases are those which follow the long-continued sport of shooting, where the deafness almost in- NERVOUS DEAFNESS. 371 variably occurs in the left ear, which is turned towards the gun during its explosion, and consequently receives the direct concussion. The treatment in recent cases when the patient is suffering from the immediate effect of the shock, consists in the removal of the con- gestion by the application of leeches, or by cupping : by the admi- nistration of mild aperients ; by strengthening the general nervous system as much as possible, and by securing the ear against the effect of loud sounds. Noises in the ears, deafness, and a feeling of deadness in the head, following the sound of a pistol shot; relief. — Mr. C. S., aged 45, a fortnight before consulting me, fired a pistol, for the first time in his life, in the open air on a cold frosty day. The concussion was in- stantaneously followed by a hissing noise in each ear, but more espe- cially in the right, and he also felt a shock throughout the whole of the head, followed by a " feeling of deadness" in it. Since the acci- dent, he has been dull of hearing, and has observed, among other things, that he could not hear the " ring of money." Leeches and mustard plasters were applied behind the ears, and small doses of calomel and colocynth were administered. Immediate relief to the head and ears followed the application of the leeches, and in a week the hearing had improved, and the noises diminished. Nervous apparatus injured hy the report of a cannon. — ^Y. L. C, Esq., aged 73, about four months before consulting me, his hearing being then perfect, was sitting in the open air at Brighton, looking upon the sea, when a cannon near where he sat was fired, without his having any idea of such a proceeding being about to take place. The concussion was immediately followed by a singing in the ears, or rather about two yards from them, and a sensation as if water were rushing through them. Since the accident, he has heard a whisper very distinctly, but a loud voice causes unpleasant jarring sensations in the ears, and deafness to all sounds. In another case, the ear was "benumbed" for some time after the patient's child had shouted into it. Nervous apparatus of the ear injured by very loud shouting ; very distressing noises ; great relief. — When surgeon to the St. George's and St. James's Dispensary, a poor man applied to me for relief from deafness and very distressing noises in the left ear. The latter had lasted several years, and the patient, a strong muscular man, thinks they were caused by the loud shouting he is obliged to 372 THE DISEASES OF THE EAR. practice as a hawker of fish. These noises came on in the left ear, and after remaining there some time advanced to the left side of the head ; they have increased lately, sometimes resembling " a rapid tinkling," at others being like the driving of a sledge ham- mer ; but most commonly they resemble the roaring of the sea. When at their loudest, as after exertion, the house seems to go round with him. The ear is quite insensible to any sound but that of these noises. The right ear is healthy. On examination, the membrana tympani of the affected ear "vvas found to be opaque, and the air passed through the Eustachian tube Mith a loud crackling. As this was a local affection, as the patient was a strong man, and as the symptoms were increased by any cause which increased a flow of blood to the organ, I determined to treat the case as one of con- gestion, and accordingly ordered the patient to apply twelve leeches below the ear, followed by a cantharidine cerate dressed with ungu- entum hydrargyra, at the same time that the outer half of the meatus was washed with a solution of nitrate of silver suflBciently strong to produce desquamation. This was followed by the use of a solution of chloride of zinc (six grains to the ounce) to the mea- tus, so as to cause a discharge. The result of this treatment was satisfactory. The noises, the patient says, " have not been so loud or nearly like it :" and ten days subsequently to this report, he said that his head was much better, and " he could do his work with- out being obliged to give up." Nervous apparatus of the ear injured by the explosion of bladders of gas. — J. B., aged 64, was admitted under my care at St. Mary's Hospital in 1853. He stated that nine months previously, directly after the explosion of two bladders of gas at the distance of a yard from his head, he suddenly became so hard of hearing, that he could not hear a voice except when spoken to distinctly at a distance of two yards from the head. The explosion was followed by a singing sound in the ears, which gradually subsided. The watch could not be heard at a distance of more than two inches from the right ear, and only when in contact with the left. The treatment consisted in the application of leeches. below the ears, but the patient did not return to report progress. The following is a well-marked case in which the nervous appa- ratus was injured by shooting. Deafness in the left ear following shooting, and temporarily in- creased by a days sport. — F. F., Esq., aged 23, accustomed to NERVOUS DEAFNESS. 373 shoot, has been gradually becoming dull in the left ear. For two years he has not been able to hear general conversation distinctly, and the striking of the clock seems no longer attended by the natural sound. Is more dull of hearing during a cold. Is not aware of any cause that could have produced the deafness. The right ear was in a natui-al state ; by the left the watch was only heard at the distance of half an inch. The treatment consisted in the use of gentle counter-irritants over and around the ear, and in doing all that could be suggested for diminishing local and general conges- tion. This treatment was followed by great improvement at the end of about three weeks, when the watch could be heard at a distance of four inches — an improvement which continued, with the excep- tion of a considerably increased amount of deafness which ensued upon a morning's shooting. This increased deafness continued for some days, and then gradually diminished. The last time the patient was seen by me, the hearing had not regained the previously im- proved state, for the watch could only be heard in contact with the ear. Not having had the opportunity of ascertaining the condition of the ear by the aid of dissection, I have assumed that in these cases, arising from shooting, the nervous system of the ear is defective. The grounds of this conclusion are, that the noises and defective hearing followed immediately on the concussion, and all the symp- toms indicated that a shock had been given to the nervous system. The secondary effect of this concussion, it can scarcely be doubted, may be anchylosis of the stapes to the fenestra ovalis. In cases, indeed, when the nervous system of the ear has received a very severe concussion, and deafness has subsequently slowly come on, I have convinced myself of this anchylosis by dissection, and will now relate one or two cases of the kind. Concussion of the nervous apparatus of the car hy thunder ; com- plete deafness. — T. D., aged 80, is so completely deaf that he can- not hear any sound. He states that, fifteen years ago, when in a thunder-storm on the coast of Guinea, he was rendered thoroughly deaf by a clap of thunder, and since then has not heard a sound. On examination, an orifice was observed in each membrana tym- pani. No treatment was attempted, but about two years after the examination, the opportunity was given me of dissecting his ears, which were in the following morbid condition. lUght ear. — At the posterior part of the membrana tympani was 374 THE DISEASES OF THE EAR. an orifice about two lines in diameter, the remaining portion of tlie membrane being white, thick, and tense, and more concave exter- nally than natural : parts were also calcareous. In the centre of the remnant of the membrana tympani is a space about lialf a line in diameter, in Avhich the epidermoid, dermoid, and nmcous layers alone remain. The long process of the incus and the crura of the stapes are gone, and the expanded base of the stapes is attached to the fenestra ovalis more firmly than natural. The membranous labyrinth was atrophied, and the nervous fibrillte of the cochlea appeared the same. Left ear. — Like the right ; except that the crura of the stapes were only partially absorbed. In another case of total deafness produced by a loud cannonading, the only morbid condition that could be detected by me, on dissec- tion, was that the otoconie was more abundant than natural, while in the vestibule there was a deposit of oval-shaped cells. Results similar to those noticed as following the practice of shoot- ing, also occur to operatives engaged in occupations involving very loud sounds. Thus in a large factory for making steam-boilers, I found a great number of men engaged in riveting the bolts, and therefore obliged to work inside the boiler, who were very deaf. It will be very interesting to ascertain by post-mortem inspection the pathological condition of the ear when subjected to such loud sounds, and some day perhaps the opportunity will be afforded me of doing so. (2.) The effect of the application of cold on the nervous apparatus of the ear. There are two classes of cases in Avhich a diminution of the tem- perature is found to be injurious to the ear : in the one cold air, in the other cold water, is the agent producing the effect. I have known engine-drivers to suff'er from deafness after being exposed to a cold blast, and huntsmen also who have had a sudden " check" when very hot, and have then stood about while a bitter east wind was blowing upon them. The effect of the application of cold seems, in the first instance, to produce congestion ; and then to lead to the symptoms of noise in the ear and of deafness, which appear to depend upon a depressed or depraved action, subsequent NERVOUS DEAFNESS. 375 to and resulting from the congestion. In what the depraved action consists, it is, however, difficult to determine. The congestion often yields to the application of leeches ; and the depraved action is fre- quently diminished, sometimes wholly removed, by the use of gentle counter-irritants, tonics, shower-baths, &c. The first series of cases consists of those in wliich the injury fol- lowed exposure to cold air. Total deafness in both ears following exposure to cold hy sleeping in the open air. — A farm-laborer, aged 28, Avas admitted under my care at the St. George's and St. James's Dispensary, in June, 1850, on account of complete deafness in both ears. He said that eighteen months previously, after sleeping in an open cart in which he was riding in the winter, a usual practice with him, intense pain came on between the right temple and ear, Avhich was relieved by the use of veratrine ointment. About three weeks after the exposure to cold the deafness made its appearance, at first for a day or two only, and then disappeared : in the course of a few days, however, it recurred with increasing intensity and once more disappeared. This recurrence and disappearance of the deafness ended after a few more days in total and permanent loss of hearing. At the present time he cannot hear a gun, even if fired close to the head. He complains of loud noises in the hfead, and of great heaviness and sleepiness. All kinds of empirical treatment had been tried on him ; oils of various kinds had been dropped into the ears, Avith brandy and salt, and then hot baked salt behind them ; every species of medicine had been given, and he had been cupped and blistered at the nape of the neck, but without producing any good effect. On examination, the upper part of each membrana tympani was found to be red, the lower part being concave and white ; air entered through the Eustachian tube and caused a loud crackino; sound. Some relief to the head-symptoms followed a discharge from each meatus, which was kept up by the application from time to time of the chloride of zinc. Deafness and singing in the ears following exposure to cold while skating. — J. V., Esq., aged 49, consulted me in March, 1852. His health was good, and his constitution strong. He stated that twelve or fourteen years previously, while skating on a bitterly cold day, a singing sound suddenly came on in the left ear, which has remained ever since ; being at times very loud, and then much subdued. A few years after this exposure, the left ear became gradually dull of 376 THE DISEASES OF THE EAR. hearinff, and receutlv Lotli the sin";infi and dulness of hearing have in- creased. The power of hearing varies, but is not worse after fatigue or excitement. With the right ear the hearing distance was three inches ; with the left, half an inch only. Two leeches were ordered to be applied below each ear, and the ears to be syringed with warm water, the object being to remove congestion. This treatment was followed by relief; but with the further progress of the case I am unacquainted. Two other cases of injury produced by the application of cold air to the ear may be briefly alluded to. The first was that of a gentle- man, aged 21, who ten months before my seeing him, being exposed to a very cold February wind blowing in the left ear, had a singing and pulsation ensue within that organ ; these sensations are unaccom- panied Avith deafness, and are worse while in bed or reading. At times they wholly disappear. The second case is that of a clergy- man, aged ^^^ who having been exposed to cold in a railway car- riage, three years before my seeing him, was subsequently attacked by a whizzing sound in the left ear, which has never ceased. By sitting up late at night, or by entering a warm room from the cold air, the sound is increased, but is better rather than worse after dinner. Complains of dulness of hearing, as general conversation is not heard. The following are cases whore the application of cold Avater re- sulted in injury to the ear : — Deafness foUoicing bathing in cold water. — T. F., aged ll>, saAv me on account of his deafness. He said, that more than a year pre- viously deafness came on sloAvly, after bathing daily in cold fresh Avater, and in a month or six Aveeks he became as deaf as at present. The affection has been stationary for some months. He requires speaking to loudly__Avitliin the distance of a yard, and at times suffers from a buzzing in the ears. He is not deafer during a cold, and docs not hear better in a carriage. The right ear is rather Avorse than the left. The previous treatment consisted in dropping oils into the ears, and in syringing them Avith Avarm Avater. In each ear the Avatch Avas heard only Avhen in contact. The mombrana tympani appeared to be slightly more concave than natural, and its surface Avas dull and congested. The treatment consisted in the application of a vesicating paper behind each ear, and in taking small doses of blue-pill and iodide of potassium, a treatment Avhich Avas followed by a slight amelioration of the symptoms. NERVOUS DEAFNESS. 377 Deafness produced in two days by dipping the head in cold water. — A girl, aged 14, the daughter of a farmer consulted mc in 1853. She stated, that two years previously^ when very much heated, she plunged her head into cold water, and two days afterwards became so deaf that she required to be loudly spoken to close to the head. The deafness varies slightly, being worse during a cold, and at times, from no assignable cause, better. The treatment consisted in keep- ing up a slight discharge from the surface of each mastoid process, and in giving small doses of the bichloride of mercury (one-thirtieth of a grain) with gentian, daily. The treatment, pursued during two months, resulted in decided improvement. Deafness and noises in the ears after bathing. — A man, aged 29, was admitted under my care at St. Mary's Hospital, in July, 1853. He said, that six years before, after bathing in a canal of cold fresh water, he became rapidly deaf in both ears, and in the course of a week was so deaf as to require to be distinctly spoken to quite close to him ; complained from the first of buzzing noises and pulsations. The deafness and the noises increase in damp weather, or when he is tired ; and he also hears worse in a carriage and amid loud sounds. The treatment consisted in the application of gentle counter-irritants over each mastoid process, and in taking alteratives, but without any beneficial effect. (3.) Deafness produced by the action of morbid poisons on the 7iervous apparatus of the ear. As has been stated, in addition to the causes just detailed, the nervous apparatus of the ear often suffers from the action of the poisons of gout, typhus fever, scarlatina, measles, or mumps. Though unable to furnish any information of the modus operandi of the several poisons enumerated, in some cases where the functions of the organ have been wholly destroyed, the nervous apparatus of the ear, on dissection, has been found by me completely disorganized, and the fluid in the cochlea and vestibule dark-colored, and occasionally tinged with blood. Many of the cases of acquired deaf-dumbness originate in the effect of poisons of various kinds. A careful con- sideration of the symptoms attendant upon these cases, and the re- sults of treatment, indicate that whatever may be the immediate effect of the poison on the nervous tissue, the secondary effect is to produce congestion of that tissue. 378 THE DISEASES OF THE EAR. Noises and deafness after rheumatic fever. — Miss. B., aged 36, consulted me in 1851. She stated, that ten years previously she had an attack of rheumatic fever, which "svas followed by dulness of hearing in the right ear, and accompanied by a constant whizzing sound and a pulsation which extended over the head. The left ear has lately become dull. The watch was heard only when pressed upon the right ear, or at a distance of six inches from the left. Neither ear presented any appearance of disease, except a slight dulness of the surface of the left membrana tympani. The treat- ment consisted in applying mustard plasters and stimulating lini- ments to the nape of the neck, and the etherial solution of cantha- rides behind the ears. The result of two months' perseverance was such an improvement of the hearing power, that conversation could be more distinctly perceived, and the watch could be heard at half an inch from the right ear. Totid deafness foUou'ing an attack of rheumatic fever. — ^Ir. M. G., aged 17, a year and a quarter before consulting me, had a bad attack of rheumatic fever, which was followed by noises in both ears and gradually increasing deafness, so that in a month after the fever he could not hear any sounds. Since the attack, has now and then heard loud sounds for a very short time : but when he saw me he was so deaf that he could not hear anything, even when the poker and tonfrs were knocked ao^ainst each other. The ears had been o o syringed, blistered, and galvanized without any effect. There was no appearance of disease in either ear. The case was at once re- garded by me as incurable. Partial deafness folloiving an attack of typhus fever. — Miss A. M., aged 16, saw me on March 1st, 1851. Eleven years previously she had an attack of typhus fever, and during the illness became so deaf as not to be able to hear the human voice. After the symp- toms of fever had disappeared, the power of hearing slowly returned, until she was able to hear when loudly spoken to close to the head. There was no appearance of disease in either ear. Partial deafness folloiving fever. — V. A., Esq., aged 40, consulted me in December, 1853. Twenty years before, he had an attack of fever, during and for some time after which he was so deaf as to re(jnire to be spoken to close to the car. The hearing gradually returned, and at the end of two years he heard perfectly well for a very short time, when the deafness as gradually returning, he soon had to be loudly spoken to within a yard of the head. Does not NERVOUS DEAFNESS. 379 now complain of noises, but lias had a ticking sound in the ears. The deafness is worse after flurry, excitement, or fatigue, after dinner, wine or beer ; a single glass of either of the latter increases the deafness instantaneously. Is better after a discharge from the nose, and while riding in a carriage. The hearing power of the left ear is gone. On examination, no unnatural appearance was detected in either ear, and the watch was heard when pressed upon the right ear. Total deafness foUowing an attack of fever. — Miss C. J., aged 21, when a child had an attack of fever, since which time she has gradually become deaf, and at the present Mioment cannot hear even a loud clapping of the hands. Five years ago both tonsils Avere partially removed, and tlieir remnants have recently been snipped, with no effect except that of producing great mental de- pression. There was no appearance of disease in any part of the organ. The poison oi scarlet fever, like that of typhus, sometimes injures the nervous apparatus of the ear, and not unfrequently complete deafness is the result. The following are illustrative cases. Didness of hearing folloiving an attack of scarlet fever. — Mrs. S., aged 26, had an attack of scarlet fever, eight years previous to consulting me, and since that time has been troubled with a dul- ness of hearing, especially during a cold. A year ago, after having suffered much trouble, and after being in weakly health, the power of hearing gradually decreased, and this decline Avas accompanied for the first time by pain, with irritation and discharge in both ears, together with constant noises like the bloAving of bellows. Is un- able to hear general conversation, but a single voice is heard dis- tinctly. The left ear is worse than the right. On examination of the right ear, the surface of the meatus was found to be dry and to contain small portions of epidermis ; the membrana tympani was opaque, and the Eustachian tube pervious. The left car was in a similar condition. Complete deafness in the right ear p>roduced by the p)oison of scarlet fever. — Mr. H., aged 20, had an attack of scarlet fever at four years of age, since which time the right ear has been so deaf as not to be able to hear even the slightest sound. On examina- tion, the right membrana tympani was observed to be more opaque than natural, and the left ear was perfect in every respect. Mumps. — The peculiar poison which causes the disease generally 380 THE DISEASES OF THE EAR, known by the name of mumps is very often the source of complete deafness, -whicli, however, usually occurs in one ear only. In these cases, the nervous apparatus is evidently affected, as the deafness comes on suddenly, is usually complete, and, as a general rule, no appearance of disease can be detected in the meatus, membrana tympani, or tympanic cavity. When the nerve is not wholly para- lyzed, and some, although it may be a very slight degree of, hear- ing remains, the only plan of treatment which can be recommended, is the use of gentle counter-irritation over and around the ears, at the same time that the ear is exercised by means of the elastic speak- ing-tube. The circulation of bile mixed with the blood is sometimes a cause of deafness, and it is also well knoAvn that large doses of quinine are also liable to be followed by temporary deafness. I have met with only one case in which permanent injury to the ear was assigned to the use of large doses of quinine. The poison o^ gont may also give rise to deafness and other pecu- liar symptoms in the head. In two cases of this affection which came under my notice, it is interesting to observe that the head- symptom complained of, viz., a feeling of vacancy, was at once relieved by pressure upon the air contained in the external meatus. Distressing sensations produced in the ears by gout. — D. T., Esq., aged 54, consulted me in June, 1857. He said that for the last four or five years he had ])een subject to attacks of gout, Avhich had at times caused him great inconvenience, and the disease had recently made so much progress as to make him fearful that his brain was weakened by its influence. lie added that he was never really clear- headed, excepting just after an attack of gout, when he supposed his blood was temporarily freed from the poison. lie had rapidly aged in the course of the previous two years. An extremely dis- tressing symptom had lately presented itself in the form of a pecu- liar sensation of vacancy in the ears, accompanied sometimes by a low hinnming sound. There was no deafness, and the patient applied to me only on account of the sensations in the ear. On examination, small deposits of gouty matter were oliscrved in the sul)stance of the right upper eyelid ; the surface of the meatus ex- ternus was of a bright red color ; the circumference of the mem- br:ina tympani and of the long process of tlie malleus were also red; while the surface of the tympanic membrane was very bright. Air passed freely, and with the natural sound, into the tympanic cavity. NERVOUS DEAFNESS. 381 The hearing power -was perfect. By -what, therefore, coukl the dis- tressing symptoms be caused ? Were they the result of congestion of the nerve ? — a condition which, it seemed to me probable, might render the nerve so exquisitely sensitive, that the ordinary sounds ever floatinor in the air niiglit become a source of excitement to the ear. Being aware also, from previous experience in similar cases, that pressure upon the external meatus so as to shut out or diminish the sound in the meatus would remove the symptom complained of, I closed with my fingers each external meatus, and the unpleasant symptoms at once disappeared. On subsequently exerting a gentle pressure on the ears by the introduction of cotton steeped in water into each, the patient was enabled to leave in comparative comfort. For the purpose of preventing the recurrence of the symptoms, it was of course requisite to diminish the congestion, for which pur- pose two leeches Avere applied below each ear, small doses of colchi- cum administered, and strict attention to diet enjoined. The quan- tity of wine was decreased from four to two glasses daily, and in lieu of beef and mutton, of which he had been in the habit of partak- ing very abundantly, he was ordered to live principally on poultry, game, and fish, with abundance of farinaceous food and vegetables. The result of this treatment was the removal of the distressing symptoms in the ears, and the gradual disappearance of the attacks of gout. (b.) DISEASES IN WHICH THE BRAIN AS WELL AS THE EAR, APPEARS TO BE AFFECTED. (1.) Debility of the nervous apparatus arising from mental excitement, A young lady, of about 25 years of age, is brought to me by her mother, on account of deafness in both ears, one being much deafer than the other. The patient is pale, rather thin, and has a look of depression. She complains of humming noises in both ears, and hears better in a carriage. Upon examination her pulse is feebler than natural, and the deafness is so considerable that she requires to be loudly spoken to within a yard of her ears. There is no mor- bid appearance in any part of the ear, and the Eustachian tube is in a natural state. On inquiring as to the origin of the deafness, the parent states that they had not been able to detect any cause. 382 THE DISEASES OF THE EAR. The ilcafnc-ss came on three years previously, when the young lady was in good health, and gradually increased, till in four months the patient had become as deaf as now. She is rather deafer after ex- citement and during fatigue. There is no hereditary tendency to deafness. The young lady has remained at home with her mother, has taken plenty of exercise in the open air daily, and retired to bed early ; but, for some reason or other, her nervous system was not strong, and she was easily excited. On further questioning, it is found, that about the period when the deafness came on, the patient Avas particularly nervous, and ultimately it turns out, by her confession, that she had been deeply grieved by the conduct of one of her friends, and had often lain awake at night indulfrinij in sor- row, and that, at such periods, the noises came on in increased force. Another young lady, aged 10, is brought just after leaving school, where she was well taken care of, and so liked l)y all, that she even preferred school to home. Iler parents stated that six months before, without any apparent cause, their daughter had grown gra- dually deaf, and can at present hear only when very distinctly spoken to, Avithin a distance of tAvo or three yards. The deafness is Avorse during excitement. There is no appearance of disease in the ears, and the girl is strong, active, and healthy ; her nerA'ous system is, hoAvever, very sensitive, her feelings most acute, and she broods in silence over slight mental troubles Avhicli Avould pass unheeded by ordinary persons. Perhaps all attempts to find out the cause of the deafness are in vain ; and the parents go away Avith the assurance from the medical man, that at the time the deafness first appeared there must have been some cause of mental excitement to call it forth. After the lapse of a shorter or longer period, the medical man learns, perhaps, that at the time in question the young lady at school suffered a great deal of mental anxiety, OAving to her reli- gious vicAAs being in an unsettled state. These tAvo cases are good t^'pcs of the class of nervous deafness now under consideration. The causes may be very numerous, and in some instances are but slight, compared Avith the distressing symptoms Avhich ensue ; but it must be borne in mind that, as a general rule, the nervous system has, from a variety of causes, been alloAved to sink into a Aveakened condition. Thus the child may have been overworked, liave suffered from indigestion, had too little exer- cise or not enough sleep : ventilation also may liave been defectiA'c. NERVOUS DEAFNESS. 383 In a depressed state of health from any of these causes, an appa- rently slight additional cause may produce the injurious efi'ect on the nervous system which hag been indicated Sometimes there is no diminution of the hearing power, and the patients complain not of deafness, but rather of singing noises, which are increased by any mental excitement. In some cases the noises are not constant, but only appear after mental emotion ; the slightest unpleasant thoughts are sometimes sufficient at once to induce the noises. The deafness and noises in this class of cases, if slight, can be cured by removing the cause (a depressed state of health), and by giving tone to the nervous system by tonics and by local applica- tions to the ear. In some cases, however, of this species of nervous deafness, the symptoms of noises become so greatly aggravated, that unless their peculiar character had been detailed by several patients, it would be difficult to credit their existence. They may commence with a gentle singing, then increase to a hissing or wiz- zing sound, that suddenly changes to a series of sharp cracks, like pistol-shots, followed by a rushing sound like the wind, or the escape of steam from a boiler, after which a rolling may ensue like thunder. These sounds vary much in intensity, being increased in some by rainy weather, in others by an easterly wind ; bodily fatigue may sometimes cause them to be magnified, but the source of increase is usually some discomfort or excitement of mind. A young lady, for instance, comes into my room with her mother to consult me, and she says that the noises became rather worse than usual when told that she was going to see a medical man ; that they Avere accelerated when entering my house and waiting in the dining-room ; and that they reached their acme of intensity after the excitement attendant upon my examination of the ears, and questioning her about the symptoms. The important problem for consideration is, can the ears be improved ? So far as my present experience extends, I may say that a large number of the worst cases can be but slightly in- fluenced by treatment; but there is still a large number which may be very greatly benefited by measures calculated to brace the nerv- ous system ; as tonics, fresh air, exercise, and mental repose. In these cases I am giving electricity a trial. Dchility of the nervous apparatus of the car, produced hy over- study. — Lady D. brought her child to me in June, 1852. The young lady was twelve years of age, thin, rather tall of her age, and pale. The pulse was weak ; the tonsils large and red ; the mucous mem- 384 THE DISEASES OF THE EAR. brane of the fauces red, thick, and rugous. The sub-maxillary glands were somewhat enlarged, and she had been subject to glandu- lar swellings in the neck. The appetite was good, and she partook freelv of meat twice daily. She was taught at home with her sister by two governesses, one being for languages. She devoted between eight and nine hours daily to her studies. The history given me was, that during the last two years, without any assignable cause, the power of hearing had gradually diminished, and there had been slight noises in the ears at times. On inquiry, it was elicited that she was greatly interested in her studies, and very anxious to make progress in them, never much tiring of her lessons. Her interest in them increased to excitement, and she was often agitated and distressed at not being able to accomplish as much as she desired. On examining the ears, a slight dulness was observable in each membrana tympani ; the Eustachian tubes were pervious, but the hearing power was so diminished, that she required to be loudly spoken to within a yard of the head. This deafness was at times so greatly aggravated, that consider- able difficulty was experienced in making the patient hear at all. It was, therefore, palpable that there was considerable debility of the nervous apparatus of each ear, for which tonics were prescribed, also a gentl^^-stimulating embrocation ; fewer hours were to be de- voted to study, and light nutritious food, as game, poultry, fish, was to be taken instead of so much meat. All this resulted in some slight amelioration ; but still the deafness was very con- siderable, and increased greatly at times. Under the circum- stances, another consultation took place, at which I clearly traced the attacks of increased deafness to more than usual nervous ex- citement following more than usual mental work. In addition to the previous tonic measures, entire rest from study in any shape was enjoined for three months, during the whole of which time the hearing gradually improved, and at the end of six months the patient was declared to be perfectly well ; and, although she has resumed her previous plans of study, moderated according to circumstances, the case remains satisfactory. To the above case the details of several others might be added, were not a brief allusion sufficient. Thus a lady, aged 27, consults me for deafness accompanied by noises Avhich gradually came on during the previous four years. The nervous system never was strong, but underwent a severe shock, about the commencement of NERVOUS DEAFNESS. 385 the period mentioned, from the breaking off of a matrimonial en- gagement. With the continuance of the mental sorrow the deaf- ness and noises had gradually increased, and were always accelerated after much mental dejection. Another lady of nervous temperament and' warm feelings, was sitting at home awaiting the return of a brother to whom she was greatly attached, when he was brought home dead from a fall in the street. For the space of a year the sister gave way to despon- dency, and, as she told me, the thought of her brother during the whole year was scarcely a moment absent from her mind. At the end of that time, as her spirits began to improve, noises appeared in the ears and head, dulness of hearing followed, and both noises and deafness so greatly increased, that in the course of another year, when seen by me, she was so hard of hearing as to require to be loudly addressed at the distance of a yard or two, while the noises had reached a pitch of extraordinary excitement. There was scarcely any conceivable sound, whether of thunder, cannon, firing guns, bells, hissing, rolling of the sea against the beach in a storm, or winds howling, to which this lady was not subject. These sounds intermixed and alternated in a manner quite indescribable. They remained of the same general intensity, varying somewhat according to the weather, for several years ; when another severe domestic bereavement occurred, followed by some new noises of a still more intense character, but her deafness remained much the same. Another lady, who married at about 26 years of age, was sub- jected to severe domestic trials, which, after preying upon her mind for some years, ended in such total deafness, that she could not hear a pistol-shot fired close to her head. The variable amount of deafness in this class of cases is sometimes very marked. Thus, I had for a long while a patient under my care who, when perfectly tranquil, could distinctly hear his daughter reading to him at about the distance of a yard ; but if his daughter told him anything which excited his interest, he became so thoroughly deaf as not to be able to hear a sound, and would remain so until the excitement vanished, when his hearing would return. 25 386 THE DISEASES OF THE EAR. (2.) DehiUty of the nervous apparatus of the ear produced hy general bodily debility. It is difficult to th'aw a correct comparison between the number of cases of deafness dependent upon excess of mental excitement, and those arising from overtasking the body ; but from the data before me, perhaps those of the class now to be considered arc the most common. They occur in both sexes, but are more fre- quently met with in the female ; and present great variety of form as well as cause. Sometimes they are temporary, and produced by a long walk, heated, rooms, late hours, &c., when noises, with di- minished hearing power, come on, but disappear after rest. Other cases, and even some of those which come on suddenly, may, how- ever, remain more or less permanent. Thus, cases have been met with in my experience, in which patients have become totally deaf after the administration of too violent a purgative, or after an attack of diarrhoea or cholera, and after the nervous exhaustion attendant upon childbirth ; in some instances of the latter, the deafness has begun with the birth of the first child, and increased with each successive birth, until at last the nervous power was wholly lost. Perhaps the most common cause of nervous deafness from physical debility is the want of proper care in the management of young persons, and particularly girls, when they are growing fast. In hospital practice, young nursemaids who carry heavy children, and whose night's rest is often disturbed, and youths just entering laborious situations, are found to suffer. Any cause, in fact, which reduces the nervous energy of the body to a state too low for the due regulation of the functions of the various orf!;ans of the frame, may be followed by a manifest depression of the nervous power of the ears, which shows itself not merely in diminished power of hear- ing, but often by singing and other sensations in the ear, and some- times by severe pain, like tic doloureux. In cases where debility of the nervous system of the ear is the result of a debilitated state of the body, the pulse, as a general rule, is weak, and there are symp- tt)ms of previous or present indigestion. Generally, no unhealthy condition of the organ itself is apparent ; though, in recent cases, the cerumen may be softer and more abundant than usual, and in old standing cases may even be absent. The treatment of cases of debility of the nervous apparatus of the NERVOUS DEAFNESS. 387 ear arising from bodily debility, consists in imparting, by every possible means, strength to the general system. Exercise in the open air, a due amount of rest and sleep, -well-ventilated rooms by day and night, abundance of nutritious food, stimulants in modera- tion, tonics in the shape of quinine, bark, strychnine, creasote, &c., should be prescribed ; Avhilc locally, gentle stimulants should be applied over and around the car. I have never found the vapor of ether applied to the tympanic cavity by means of the Eustachian catheter of any service ; nor has my limited experience of the use of galvanism and electricity hitherto been favorable to their em- ployment. Some cases are decidedly amenable to treatment, and the noises diminish or disappear, while the deafness is greatly diminished ; but if the cause in Avhich the deafness originated be allo\yed to continue, or if any debilitating influence be present, total deafness may ensue in spite of every remedial effort. The following cases are all interesting. Deafness produced by want of sufficient sleep ; cure. — In the earl}^ part of 1855, a young gentleman, aged 14, was brought to me by his father, on account of gradually increasing deafness. lie ap- peared to be in tolerable health, and was at school in the neighbor- hood of London. No cause could be assigned for the afiection, which had so far advanced as to cause him great discomfort from his ina- bility to hear what his masters said to him. On examination, it became apparent that the deafness depended upon debility of the nervous system, for there was no history of any other disease, nor was there any appearance indicative of disease. The patient had, however, occasional noises in the ears, following over-exertion, and he certainly was deafer when he was tired. On inquiry, I could discover no special cause for the deafness, as he followed the same rules and regulations which Avere pursued by all the boys in the school. I prescribed internally quinine, and a stimulating liniment externally, giving directions that he should not be over-Avorked. In a month's time the boy Avas seen again, but remained in much the same state, so I requested to be alloAved to see the lady with Avliom he boarded, in order to ascertain further particulars as to his mode of living. On the most minute questioning no sufficient cause could be detected, except that, being very desirous to prepare his lessons Avell, he sat up so late that Avlien the time arrived for getting up, he Avas so sleepy as to be roused Avith difficulty. It Avas at once rendered probable, that the debility of the nervous apparatus of the 388 THE DISEASES OF THE EAR. ear might be dependent upon the want of sleep ; and I therefore recjuested his friends to see that his duties were so relaxed that he could take as much sleep as he required, and gave directions that he should go to bed at eight o'clock, and sleep until he awoke of his own accord. The result was, that for several successive nights, he slept for fourteen hours, and by degrees the number was reduced to ten, which was his usual allowance for three weeks, at the end of which time he returned to me, when, to the gratification of all, it was found that his hearing was nearly restored, and he was no longer styled " the deaf boy" at school. This patient has been seen by me twice or thrice since, at considerable intervals, in consequence of the deafness returning ; but each time it was evident that the ner- vous system had been too much exhausted, and the administration of quinine, with less work, and an increase in the amount of sleep, soon restored the hearing. Total deafness produced hy the nervous shock consequent upon successive accouche j?ients. — Mrs. B., aged 40, pale, and of a nervous temperament, consulted me in 1850, on account of complete deaf- ness in both ears. She stated that she had married in India ten years previously, and at the time of her marriage she could hear perfectly well. On the occasion of her first confinement, previous to which her hearing was still perfect, she sufiered a good deal from exhaustion, and this was followed by a great degree of deafness, so that she could scarcely hear what was said to her, even when the voice was much raised. Upon getting up, and growing stronger, the deafness was so much relieved that she merely required to be spoken to a little louder than usual. During each successive con- finement in India, amounting in all to four, the deafness greatly in- creased, and after each recovery became more permanent, until, on the last occasion, she remained as deaf as at present, when she is oblir'ed to have recourse to signs. Indeed, she has never heard the voices of her younger children, and can only by the movements of their lips understand their words. Debility of the nervous apparatus of the ear arising from over- exhaustion in India. — Captain T., aged 40, came home from India in 18')8, having undergone great fatigue, and his health having been greatly shattered, while his hearing power had so much diminished, that when he consulted me I was obliged to speak very distinctly within a yard of his head. He complained of constant loud singing in the ears, which was increased by the slightest exertion. On ex- NERVOUS DEAFNESS. 389 amining the ears, no alteration from tlie normal condition could be detected, and the Eustachian tubes Avere in a natural state. The treatment consisted in sending the patient to the seaside and in giving him quinine, using at the same time a stimulating liniment over the ears and at the back of the neck. In two months his strength had greatly increased, with a corresponding improvement in the hearing. He returned to the seaside to pursue the treatment in capital spirits, and was induced to go out on two consecutive days to evening parties, at which he stayed till very late. Nervous ex- haustion followed, and his hearing sank to the same low ebb as when he first consulted me : nor was it until after two months of very quiet life and steady keeping to the prescribed treatment, that he again began to improve. Nervous deaftiess produced hy over-exertion. — E. Clarke, aged 31, a tall muscular carter, was admitted under my care at St. Mary's Hospital, on January 27th, 1859. He stated, that fourteen years before, when out of health, deafness came on in the left ear, accom- panied by noises, sometimes like a kettle singing, at others, like the ringing of bells. On recovering his health, he found himself per- fectly deaf in the left ear, which has remained so ever since. Eleven weeks ago, when a good deal exhausted by hard work, he took a bad cold, daring which singing came on in the right ear, with loud noises, like the ringing of bells, and were accompanied with so serious an amount of deafness, that he required to be spoken to in a loud voice, within a yard of his head. The patient's pulse Avas weak, and he had a worn aspect, as from exhaustion of the nervous system. On examination, no appearance of disease Avas visible in either ear, and the Eustachian tubes Avere pervious. Two grains of quinine were ordered to be taken tAvice daily, and a stimulating liniment to be rubbed over the surface of the ears, at the back of the neck, and doAvn the spine. In the course of a Aveek the noises decreased greatly, and in a fortnight they had Avholly disappeared, while the hearing poAver gradually increased ; so that Avhen he left the hospi- tal, at the end of six Aveeks, to use his oaa'u words, he " at times hears quite nicely." Several cases of a similar character might be cited, in Avhich equally favorable results folloAved the administration of strychnine, in doses varying from one-thirtieth to one-tAventieth of a grain, tAvice or thrice daily ; and in some instances, Avhere neither quinine nor strychnine 390 THE DISEASES OF THE EAR. were of any benefit, doses of creasote, or of morphia, or of both to- gether, "vvere productive of great improvement. Kervous deafness relieved by creasote and morphia. — Miss M., aged 29, in good health, but very easily excited, consulted me in January, 1859, on account of deafness. Four years previously her left car gradually became deaf, accompanied with noises very diffi- cult to describe, but something like a whizzing, and these noises were increased by any external noise, or if she felt nervous, tired, or excited, and were worse at night. In a few months the right ear was also affected in the same way. In both the deafness was gradually increasing. This deafness was also accompanied by a sudden loss of voice after she had spoken a few words. The only cause to which she can ascribe the deafness was the habit of going for many hours without food, and then eating very rapidly. She had been treated by blisters, whose use had been followed by a rapid advance of the deafness, and she had been told that her case was in- curable. At the time of her first consulting me, it was requisite to speak loud Avithin a yard of her head, and she was deaf to all gene- ral conversation. On examination, each membrana tympani had a perfectly natural appearance, and the Eustachian tubes were healthy. The treatment consisted in using gentle counter-irritation over each ear, the back of the neck, and down the spine, and in administering creasote and morphia, in doses of two or three minims of the former to one-twelfth of a grain of the latter, twice daily. This treatment was continued perseveringly for four months, at the same time that every measure for restoring the general health as respects food, ex- ercise, and diet, were resorted to, and at the end of the treatment the hearing power was so greatly improved that she could both hear and take part in general conversation. Cases of nervous affection of the ear sometimes occur in which the chief symptom is i)ain ; the treatment does not differ from that of the last class of cases. Pain in the left ear, accompanied hy diminished power of hearing, folloiving overfatigue. — Miss T., aged 25, pale and not strong, was brought to consult me, in May, 185G, on account of a pain in the left ear ; this pain had made its first appearance about a year before after the patient had undergone considerable fatigue by attending several evening parties in succession, and remaining very late; and the pain Avas much accelerated by any cause which produced fatigue. The hearing power was very slightly affected ; and as the other ear NERVOUS DEAFNESS. 391 was perfect, no complaint Avas made respecting the hearing. On examination, the organ appeared to he quite healthy ; and feeling that the pain arose from deranged action of the nerve consequent upon dehility, quinine "was prescribed internally, and mild stimulants applied over the ear and down the spine. This treatment was fol- lowed by considerable success, as the pain disappeared in the course of a month, but returned slightly upon the patient having to undergo great fatigue. CHAPTER XVI. THE DISEASES OF THE NERVOUS APPARATUS {concluded). ULCERATION OK TUE MEMBRANOUS LABYRINTH — CARIES AND NECROSIS OF THE PETROUS BONE. In the cases hitherto described of disease extending from the tym- panic cavity to the brain, tlie upper osseous wall of the tympanum was the part affected, and the medium through which disease ad- vanced to the middle cerebral cavity. There is, however, another medium by which disease may be conveyed from the tympanic cavity to the brain ; and that is through the labyrinth. When it is re- membered that at the inner wall of the tympanum a delicate mem- brane (membrana fenestrre rotunda?) is all that separates it from the cochlea, and that the base of the stapes with its fine ligaments form the only septum between that wall and the vestibule, it will natu- rally be inferred that disease in the tympanic cavity would fre- quently advance to the labyrinth. The occurrence is, however, in fact, very rare, for this reason, that ulceration of the mucous mem- brane of the tympanum is far from a common disease, while, under the influence of chronic inflammation and of the secretion collected in the tympanum, the membranes both of the fenestra rotunda and ovalis become thickened and turgid. I am not aware that any case has been recorded in which disease had made its way through the fenestra rotunda to the labyrinth ; but in the course of my dissections I have found the medium of communication to have been, in one instance, the fenestra ovalis, and, in the other, a carious aperture in the outer arm of the ex- ternal semicircular canal, where it bulges into the tympanic cavity, and is covered by the tympanic mucous membrane. "When suppu- ration takes place in the labyrinth, the disease readily advances through the cribriform floor of the meatus auditorius internus to the auditory nerve, and thence to the base of the brain and medulla ob- NERVOUS DEAFNESS. 393 longata. In certain cases purulent matter is efTused beneath the arachnoid over the whole surface of the base of the brain, surround- ing the nerves in their cranial course; and the substance of the pons Varolii or medulla oblongata may be destroyed by ulceration, or an abscess may form between the arachnoid and pia mater. In some cases the disease extends a considerable distance down the medulla spinalis. In some cases the labyrinth becomes carious or necrosed, and the dead bone is discharged without the production of any symptoms of cerebral disturbance, as in the following cases. The first oc- curred to my friend Mr. Hinton, who kindly placed the preparation in my museum. It was of a man net. 55, who suifered from a dis- charge from the right ear for some years, and at last the cochlea was discharged entire. The second case occurred to Mr. Shaw, and the following report is extracted from the seventh volume of the Transactions of the Pathological Society of London : — Extraction from the left ear of a hoy of the greater jJart of the jJetrosal portion of the temporal bone, including the meatus auditorius in- ternus and labyrinth, separated by necrosis. "A boy from the country, net. 7, Avas admitted into the Middlesex Hospital on the 31st of July, 1855, under Mr. Shaw, for otorrhoea aifecting both ears. The disease succeeded a severe attack of scar- let fever, Avhich he had two years and a half ago. From the right ear the discharge of pus was not of great amount. The left ex- ternal ear projected considerably beyond its proper level, and an irregular piece of bone, surrounded with fungous granulations, pro- truded from the meatus into the concha. He had paralysis of the muscles of the left side of the face ; for a year he had been com- pletely deaf in both ears. " On the 3d of August, he was put under the influence of chlo- roform, when Mr. Shaw first extracted the piece of bone which projected into the concha ; this appeared to have been the posterior border of the external meatus of the temporal bone. " The cartilaginous tube having been ulcerated by the pressure of the loose fragment, the point of the little finger could now be passed inwards to some depth ; when another larger piece of bone was felt rolling freely in the cavity. This was seized by the dressing 394 THE DISEASES OF THE EAR. forceps ; and after it liad slipped once or twice, owing to its hard- ness and smoothness, it was extracted by employing force and a twisting motion, so as to favor its coming in a proper direction. For a few seconds after the removal dark venous blood flowed rather freely. As a precaution, he was kept in bed for a week ; by degrees the discharge lessened, and the ulcer of the tube cicatrized. No outward symptoms arose ; and in the end of September, except from the paralysis of the face, the deafness, and a trifling discharge from both ears, he left the hospital in good health." Description of the Specimen. — The density of structure, Aveight, and shape of the portion of bone last removed, at once showed that it formed nearly the whole of the petrous portion of the temporal bone. It was of irregular cylindrical, or rhomboidal figure ; it mea- sured one inch in length ; its average thickness in various directions was half an inch ; it weighed twenty-two grains. On one side, nearly in its centre, was an opening and cavity with well-defined borders and walls, which was recognized to be the meatus audito- rius internus. The depth of the meatus, from the margin to the thin perforated plate through which the auditory nerve penetrates into the labyrinth, was three-fifths of an inch ; and, as that is the full depth of the cavity in its normal state, it was thereby shown that the whole of the internal meatus was included in the specimen. At the bottom of the meatus could be seen the commencement of the canal for the portio dura. On the side of the specimen in rela- tion with the brain, the surface presented the cancellated appearance peculiar to the diploe ; whence it was concluded that, in the detach- ing of the necrosed part, the process of separation had taken place in the diploe — that the cortical layer had retained its vitality, and, remaining in contact with the dura mater, had served as a barrier to prevent disease from extending to the cerebrum. On turning the bone around to view it in its opposite aspect, the side then exposed was seen to be the internal wall or boundary of the tympanic cavity; it was easy to distinguish the ''promontory," having above it the "fenestra ovalis," and below it the "fenestra rotuTida;" the two latter openings were broken and irregular, and through tlie enlarged holes thus produced the interior of the "vestibule," with its fossae, the cochlea, modiolus, and lamina spiralis, somewhat injured, were seen. At the posterior part of the specimen portions of the semi- circular canals, broken ofi" near their junction with the vestibule, stood up distinctly into view. NERVOUS DEAFNESS. 395 In other instances, although the brain is seriously implicated, the patients recover, as in the following case quoted from Mr. Wilde. He says: "I am indebted to Sir Philip Crampton for an examina- tion of one of the most extraodinary pathological dissections of diseased bones perhaps in existence, consisting of the entire in- ternal ear, cochlea, vestibulum, and semicircular canals, "with a small portion of the inner -wall of the tympanum, -which he drew forth from the meatus of a young lady who, after the most urgent symptoms of inflammation of the brain, with paralysis of the face, arm, and leg, and total deafness of one side, recovered from the bad symptoms and the paralysis of the extremities after a copious dis- charge from the ear. This discharge, the paralysis of the face, and deafness, continued some time, accompanied by occasional attacks of pain in the ear, till one day Sir Philip, perceiving a portion of loose bone lying deep in the cavity of the meatus, drew forth the specimen from which the illustration in the volume was made. It does not appear that the hard external enamel of the bone was affected, but the scala cochleae is far more beautifully displayed than could possibly have been done by art." In the following case, which, on several grounds, is one of great interest, the disease advanced through a carious orifice in the semi- circular canal to the labyrinth. Disease in the tympanic cavity, extending through a carious orifice in one of the semicircular canals to the labyrinth, and thence hy the auditory and facial nerves to the brain. — On the 28th of March, 1851, I was called in by Mr. Such, of Dalby Terrace, City Road, at the request of Mr. Coulson, who had also seen the patient, to see a German gcntleniffti, aged 26, the history of whose case I found to be as follows : — He was of a robust constitution, and had generally enjoyed the best of health: indeed, even when first seen by me, he had the appearance of a stout, hcaltliy man. Between four and five years previously, he complained of occasional pain in the right ear, which was usually followed by a discharge that by degrees be- came constant. Three weeks before my seeing him, he suifered from a severe attack of pain in the head, which ceased on the occurrence of an increased quantity of discharge. Nothing par- ticular happened further until ten days previous to my visit (except- ing a sleepless state at night), when he was suddenly seized with a violent pain in the head, whicli the ordinary remedies failed to relieve ; and by degrees this pain extended to the back of the neck, 396 THE DISEASES OF THE EAR. and as low as the sixth dorsal vertebra. About the same time there Avas paralysis of the right facial nerve. For several days there had been a continual shivering fit about two o'clock P.M. On the evening of the 28th, at whicli time I saw him, he was suffering from great pain at the back of the neck ; was very restless, par- ticularly at times, but talked quite sensibly ; the right facial nerve was paralyzed ; he squinted, and the pulse was 85. The external meatus was nearly filled by a polypus : the discharge was very fetid and abundant. A large blister was ordered to be applied to the nape of the neck ; the car to be frequently syringed with hot water ; and, as the patient was very sensitive to the action of mercury, a quarter of a grain of gray powder, Avith three grains of extract of henbane, were administered every two hours. March 20th, 9 p.m. — The mercury has already caused great ten- derness of the gums. The symptoms have materially increased ; the pain at the back of the head was very violent this morning, the squinting continues, and he sees double. At three o'clock to-day he became insensible, but was roused by a loud noise, and spoke rationally for a minute or two, but then relapsed into a state of incoherency. Pulse as yesterday ; respiration oppressed and low ; face and head congested and blue ; discharge from the car abundant and fetid. Leeches were applied below the ear. March 30th. — Slight relief followed the application of the leeches, but the patient soon grew rapidly worse. The right side of the body became paralyzed, the breathing stertorous, and the face livid. Insensibility gradually came on, and he died at 6 p.m. Autopsy, tivclve hours after death. — With the exception of a large quantity of chocolate-colored fluid in the lateral ventricles, the cerebrum was healthy, as was also the cerebellum. The arachnoidal surface of the dura mater, covering the superior and mastoid sur- faces of the petrous bone, was in a healthy state ; but upon removing it from the bone, over two small portions of both surfaces, it was found to be softer than natural, and these soft portions covered apertures in the diseased bone. The appearance of disease was, however, so slight, that it was quite manifest that the affection of the ear had not made its way inwards at either of the two points. On removing the brain, there was evidence of very extensive disease at its base. Purulent matter was deposited beneath the arachnoid, from the roots of the olfactory bulbs, anteriorly, to the medulla ob- longata, posteriorly. In some parts this pus was of a dark color ; NERVOUS DEAFNESS. 397 in others, as in the pons Varolii, the arachnoid membrane was ulcerated. The principal seat of the disease "was the right side of the pons Varolii, the substance of which was ulcerated to the depth of a line to a line and a half, over a surface as large as a sixpence. All the nei'ves, at their origins, were surrounded Avith pus, and the substance of the facial and auditory nerves of the right side Avas so soft as to be scarcely distinguishable from purulent matter. On examining the petrous bone, the dura mater around the orifice of the meatus auditorious internus Avas observed to be softened and de- tached from the denuded bone. The portions of the auditory and facial nerves Avithin the meatus Avere also in a state of suppuration. The Avhole of the petrous bone being removed for the purpose of careful dissection, the following was the condition of the parts detected. The external meatus contained tAA'O polypi, one of Avhich, as large as a small pea, A\'as attached, by a broad base, to the poste- rior wall of the meatus, about its middle ; the other, and smaller, about the size of a grape seed, was also attached to the meatus near the former. When the membranous meatus Avas separated from the bone, there Avas found in the latter an orifice between tAvo and three lines in diameter, so that a communication existed betAveen the meatus and the mastoid cells ; there Avas, hoAvevcr, no orifice in the membranous meatus, and consequently the discharge from the ear came not from the mastoid cells, but from the surface of the meatus only. The membrana tympani was entire, but quite Avhite and much thicker than natural. The tympanic cavity contained a large quantity of fetid pus, and its lining fibro-mucous membrane was ulcerated at several points. Within the cavity there were also tAvo portions of carious bone, one projecting towards the cavity of the cerebrum and in contact Avitli the outer surface of the dura mater ; the other, looking towards the cavity of the cerebellum and also in contact Avith the dura mater, Avhich membrane, as before stated, Avas, at the points referred to, thick and soft. The ossicles Avere present, and the stapes adhered Avith its usual degree of firmness to the circumference of the fenestra ovalis. On laying open the cavity of the vestibule, it Avas found to be full of a dark-colored pus, having a fetid odor; the semicircular canals were also full of similar mat- ter, and the osseous Avail of the superior canal Avas carious at tAvo or three points. This purulent matter extended from the vestibule and cochlea to the meatus auditorious internus. While carefully examining the external semicircular canal, Avhere it makes a bulging 398 THE DISEASES OF THE EAR. in the tympanic cavity, a small carious aperture, not larger than a small pin's head, ^vas detected in it, which contained fetid pus, and was the only medium through ■which disease could have been trans- mitted from the tympanic cavity to the vestibule. Fig. 99. Caries of the External Semicircular Canal. A bristle is iilaced through the aperture in the Semicircular Canal, showing the conimunieation between the Vestibule and the Tympanic Cavity ; the upper wall of the Tymi)anum has been cut away. I have described this case as one of disease orifrinatinor in the tympanic cavity, and extending thence to the vestibide, inwards, and to the meatus, outwards. The grounds for my belief that the disease originated in the tympanic cavity are various. In the first place, it is very rare for suppuration to originate in the labyrinth, nor do I recollect ever to have met with a well-marked case of the kind : and had it, in this instance, originated in the labyrinth, it would most probably have produced death before it reached the tympanum. In the second place, the tympanum is, as has been stated, a frequent seat of disease ; and the presence of the un- detached portions of necrosed bone indicates long-standing disease. The nature and progress of the disease would appear to have been the following : — AVhen it first made its appearance, it was probably one of catarrh of the mucous membrane ; the quantity of mucus secreted was too large to admit of its entire escape through the Eustachian tube ; the membrana tympani was consequently pressed NERVOUS DEAFNESS. 399 upon, and, instead of ulcerating and allowing the matter to escape externally, became itself much thickened and very rigid ; the secre- tion being thus confined in the tympanic cavity, produced caries of the bone and penetrated the labyrinth. There can, it seems to me, be no doubt, that had the membrana tympani been partially de- stroyed, and free egress been in that way afforded to the secreted matter, the disease in the bone might have been prevented, and the life of the patient by that means saved. Another opportunity Avas kindly given to me, by the late Mr. Avery, of seeing the post-mortem, and making a careful dissection of the ear, in a second case of disease advancing from the tympa- num to the labyrinth. In this instance, the medium of communica- tion Avas the fenestra ovalis, Avhich had been left open after the removal of the stapes by ulceration. Ulceration of the tympanic mucous membrane; extension of dis- ease to the labyrinth through the fenestra ovalis. — James Warner Smith, aged 17, a sailor, was admitted into the Charing Cross Hos- pital, on the 14th of January, 1846. The history of his case was, that at five years of age he had an attack of measles, followed by an abundant discharge from the left ear, from which he has never since been perfectly free, although occasionally the quantity was very small. He had usually enjoyed good health. Three months previously, Avhen off the Cape of Good Hope, he was up aloft during a gale, and lost his cap. Great pain in the ear followed this acci- dent, and the quantity of discharge increased. There have been many attacks of pain since, and occasionally a sanguineous dis- charge. When he came on shore, he took a fresh cold, and the pain in the head and ear became very violent. He now consulted a surgeon, Avho ordered him injections, drops, and ointments ; but not obtaining any relief, he applied to Charing Cross Hospital. At the time of his admission, he complained of constant pain in the left ear, and in the left side of the head as high as the vertex, with a certain degree of pain also on the right side. The muscles on the right side of the face were constantly twitching, and the mouth was as constantly drawn to that side. Some intolerance of light was also observed. An abundant offensive discharge proceeded from the left ear ; but there was no tenderness over the mastoid process. January 16th. — Has had a violent paroxysm of pain in the night, but is better this morning, and the twitching has subsided, except in the right eyelid. Calomel and opium were administered. 400 THE DISEASES OF TUE EAR. January 22(1. — Much better ; slept well ; pain abated. January 24th. — Pain returned as violently as ever. January 27th. — Delirious during the whole of the day. January 29th. — Delirium continues : complains of intense pain in both sides of the head ; discharge from the ear abundant ; head drawn backwards. January 30th. — The delirium has left him, but he is exceedingly drowsy, and is roused with great difficulty. The movements of the limbs and their sensation unaifccted. The pupils acted pro- perly. February 1st. — The drowsiness has vanished ; has liad no deli- rium ; and has passed a good night ; but still complains of consi- derable pain in tlie ear and over the eyes. He remained in this state until the 5th, when he gradually sank, without coma or cerebral symptoms of any marked character. The retraction of the head continued to the last. He was quite sensible before he died. Autopsy, tliirty-six liours after death. — On removing the dura mater, the surface of the arachnoid was observed to be remarkably dry ; the vessels of the pia mater were more than usually injected on the convex surface of the hemispheres ; there were two or three small yellow patches beneath the arachnoid. Each lateral ventricle contained at least three ounces of clear fluid ; in the posterior corner of the right, and in the inferior of the left, Avere two patches of bright yellow lymph, as large as half-a-crown, which were covered by a thick creamy purulent fluid. The third ventricle contained a dark clot of blood, of the size of a small walnut, which could be traced into the fourth ventricle, where there was also a small coagu- lum. The commissura mollis was broken down. Surrounding the lower part of the commissure of the optic nerves, and covering the pons Varolii, crura cerebri, medulla oblongata, and upper part of of the medulla spinalis, was a layer of pure yellow pus and lymph, nearly h;ilf an inch thick ; it embraced the nerves at the base of the brain to their passage through their several foramina. The parts in direct contact with this layer were very soft. Under the pia mater, where the right anterior lobe rests on the orbital plate of the frontal bone, there was a patch of effused blood, the size of a shilling. The dura mater covering each petrous bone was healthy, and the exterior of the bone did not present any appearance of dis- ease. On examining the cavity of the ear, the membrana tympani NERVOUS DEAFNESS. 401 was found to have been destroyed by ulceration, and all the ossicles had disappeared. The tympanic cavity was full of the most offen- sive secretion, and its lining membrane was ulcerated. The fenestra ovalis was open, and, in tiic cavity of the vestibule, similar matter was found to that in the tympanum. The whole of the natural membranous labyrinth had been destroyed. The auditory nerve was tumefied, and of a dull livid color, the disease having evidently advanced to it through the cribriform floor of the internal aiulitory meatus, and thence to the base of the brain. It is to be remarked, that in this case there appeared to be no obstacle to the free egress of the matter, except the accinnulation of thick masses of it in the cavity of the tympanum. It is far from improbable that, in cases of ulceration of the mucous membrane of the tympanum and loss of the stapes, the thick secretion in the tympanum may be quite sufficient to cause the disease to advance inwards. The case is also another illustration of the necessity there exists for frequently washing out the tympanic cavity with Avarm water. It is, however, no doubt possible, ere the stapes is removed, for the disease to advance to the vestibule without the agency of the pent-up matter in the tympanum. Besides the two cases just described, I have met with two others ; and as these four cases are the only instances I have found on re- cord of this peculiar form of the disease, brief particulars of the two latter are subjoiiied. The first of these cases occurred in the practice of Mr. Streeter, and was laid by him before the Westminster Medical Society on the 13th January, 1844. Disease extending from the tymjianic cavity to the labyrinth, and thence to the medulla oblongata and the base of tlie brain. — The patient was a lady, aged 42, who had been deaf in the right ear since the age of seven, but from what cause Avas not known. Two or three months previous to her death, she became affected with a severe headache, for which a blister was applied at the back of the neck. Nothing serious, however, was thought of the matter until the 17th December, Avheu the severity of the pain so increased as to become of a maddening character, and almost to produce delirium. The right portio dura nerve was paralyzed, and there was severe pain doAvn the spine, Avhich was attributed to a fall received when getting out of bed. The pulse did not warrant active depletion, but two or three leeches were applied behind the affected ear ; a large 26 402 THE DISEASES OF THE EAR. poultice was applied over the face ; the ear was gently syringed with warm water, and saline medicines were ordered. On the 18th she had some sleep in the night, but complained of an almost intoler- able pain in the back. The catamenia now appeared, and the cause of tlie i)ain remained obscure. She was quite sensible, the pupils acted, but the cornea on the affected side had begun to ulcerate. There was a slight discharge from the right ear, and the left had become somewhat deaf. It was thought that a hole could be ob- served in the membrana tympani : calomel and opium were admi- nistered. December 19th. — She has slept better and remained somewhat improved until five or six in the evening of the 21st, when she was suddenly seized with coma, and continued in that state until the following morning, when she died. Autopsi/. — On examining the brain, slight sub-araclinoid effusion and vascularity of its surface were found, as also some increase of vascularity in the interior ; but there was no effusion in the ventri- cles. An abscess was discovered in the tympanum and labyrinth, and there was a counter-abscess, about the size of a large pea, in the condensed araclmoid and pia mater, occupying the fossa where the facial and auditory nerves proceed, from the junction of the medulla oblongata with the pons Varolii and cerebellum. Pus was effused beneath the arachnoid and pia mater, investing the right side of the upper portion of the medulla oblongata, and the adjoin- ing part of the right lobe of the cerebellum, to about the extent of a square inch ; but there was neither softening nor apparent lesion of the proper cerebral tissue beneath. The exact condition of the tympanic cavity and labyrinth is not detailed in the al)Ove notes by Mr. Streeter ; but there can be no doubt that tlie disease (most probably ulceration of the mucous membrane) had extended from the tympanum to the vestibule, either through the fenestra rotunda or ovalis, or by means of an orifice in the osseous wall of the labyrinth. The state of the portio dura and portio mollis nerves is not stated; but judging from the records of other cases of a similar character to the present, these nerves must have undergone some morbid change and communicated the disease to the base of the brain. Tbe remaining case is taken from M. Itards work,' and is as ' Trnite des Maladies de I'Oreille. 1821. Tome i, p. 254, Obs. 22. NERVOUS DEAFNESS. 403 follows : A man, aged 22, five weeks before his death, complained of toothache: this was followed by febrile symptoms. On the twelfth day after the attack, discharge took place from the left ear, but symptoms of cerebral irritation increased until lii.s death. Autojjsy. — Over the convex surface of the brain, and in its sub- stance, were a number of small purulent deposits. The cerebellum was similarly affected, but in a less degree. The auditory and facial nerves were in a state of suppuration, and almost wholly destroyed : pus was also found in the internal auditory meatus, the vestibule, cochlea, and semicircular canals, and the tympanic cavity. The treatment to be pursued in these cases is similar to that recommended in cases of disease of the tympanum and the mastoid cells. CHAPTER XVII. MALIGNANT DISEASE OF THE EAR. ORIGIN IN THE MCCOCS MKMBRANE OF THE TYMPANUM — DESTRUCTION OF THE PETROUS BONE — SOMETIMES MISTAKEN FOR POLYPUS — OPERATIONS TO BE AVOIDED — BRAIN AND DURA MATEU INVOLVED — TREATMENT. Cases of malignant disease, advancing from the ear towards the brain, appear to be of rare occurrence. So far as my own expe- rience and tlie aid of published cases permit me to judge, it appears most probable that the part of the ear in which malignant disease usually originates, is the mucous membrane lining the cavity of the tympanum. After the diseased growth has destroyed the merabrana tyuipani, it advances through the external meatus to the outer orifice, where it shows itself in the shape of a small tumor, Avhich has sometimes been mistaken for a polypus, and the removal of which has caused hemorrhage and an aggravation of the symptoms. At the same time that the disease advances outwards, it also encroaches upon the whole of the parts surrounding the organ of hearing. The osseous walls of the meatus externus and of the tympanic cavity are wholly destroyed ; the outer part, and even the whole of the petrous bone, are converted into a mass of disease ; the lower part of the squamous bone also disappears, and the tumor ailvanccs into the cavity of the skull, where it destroys life, cither by its pressure upon the brain or its bloodvessels, or by involving the brain itself in the disease. This malignant disease is sometimes of the nature of fungus hsematodes ; at other times it has the characters of encephaloid disease. This affection occurs at various periods of life: the ages of the three patients to whose cases reference is about to be made, were respectively 3, 18, and 35 ; the progress is very rapid gene- rally, and forms a marked contrast with those cases of chronic MALIGNANT DISEASE OF THE EAR. 405 disease of the ear advancing to the brain, to which attention has hitherto been drawn. Sophia W., aged 35, a single woman, was admitted under my care into St. Mary's Hospital, on the 14th July, 1854, The history, as given by herself, is, that after a severe cold, a year previously, the right ear suddenly became painful, though the pain was not very severe. Since the above period, the pain has been gradually in- creasing, accompanied by a tumefxction of the right side of the face. Six months ago a red growth Avas removed from the tube of the ear, which the surgeon considered to be a polypus, and since then she has had at times a good deal of bleeding from the ear. Lately the pain has greatly increased, and has extended over the side of the head and the face ; a small round swelling has also appeared at the orifice of the ear. On examination, the external ear was observed to be much redder than natural, and somewhat hypertrophied ; and the orifice of the meatus was closed by a red tumor, about the size of an almond, upon pressing one side of which a small quantity of sanious discharge issued from the meatus. The inteo;uments around the ear, for the distance of an inch and a half, were red, soft, and somewhat elevated above the surrounding parts by a tumor beneath them. The left portio dura nerve Avas completely paralyzed ; there was much pain of a pricking and shooting character complained of in the region of the tumor, and this at times extended inwards to the brain. The treatment consisted in occasional'y applying a leech or two in the region of the ear, so as by diminishing the congestion, to relieve the pain ; small doses of morphia were frequently admin- istered, and the general health supported ; the meatus was frequently syringed with warm water, and emollient applications made to the tumor. These remedies, however, led to very transient amelioration of the symptoms ; though the pain would sometimes subside, the patient was subject to frequent and severe relapses. She was able, however, to walk about the ward, and a few days previous to her death expressed a wish to leave the hospital in order to visit her friends in the country. On the 23d of October, she did not com- plain more than usual of the pain in the face and head, but on the 24th and 25th there were symptoms of considerable cerebral conges- tion, she Avandered a good deal, and the head was evidently a source of great distress to her. The symptoms of congestion gradually in- creased, and she died on the 28th of October. Autopsy. — The integuments of the external ear, and those cover- 406 THE DISEASES OF THE EAR. ing the tumor, ■were red and tumefied. Upon reflecting the ear and the integuments from the tumor, a large mass was exposed, Avliich extended from the posterior part of the mastoid process, posteriorly, to the body of the malar bone anteriorly, and also from half an inch below the squamous suture to the angle of the inferior maxilla below. The tumor was intimately connected with the integuments, and of a reddish-white color. It presented different degrees of con- sistence, being in front, where it surrounded the ascending ramus of the lower maxilla, quite hard and firm like the pancreas, while more posteriorly it was softer ; and deeper towards the styloid process, there was a large quantity of a white creamy fluid. Both anterior and posterior to the external auditory meatus, the tumor contained small spicuUx! of bone. The mastoid process was involved in the disease, and Avas deduced to some detached masses of bone in the middle of a portion of the tumor. The osseous meatus had wholly disappeared, and the remains of the , membranous meatus could scarcely be distinguished, its walls having become so much involved in the diseased mass. The only remains of the tympanic cavity were some portions of the mucous membrane, having a dark livid hue, with distended bloodvessels, and small red growths attached to it. Not a remnant was left of the bony cavity. The whole of the squamous bone, from an inch below the squamous suture, and the whole of the outer part of the petrous bone had been destroyed, so that the apex of the petrous bone had no connection with the squa- mous. The tumor had advanced inwards to the cavities of the cerebrum and cerebellum, through the aperture formed by the destruction of the squamous and petrous bones. In the middle cerebral fossa was a reddish-white tumor, of about the size of a small pear, which consisted of two portions, one below, and the other above, the dura mater. The part below the dura mater was directly continuous with the external tumor, while the large portion above seemed to be an indejjendent growth from the free surface of the dura mater, and connected to the larger mass of the tumor by bloodvessels only. The upper part of this portion of the tumor was adherent to the lower surfiice of the left middle cerebral lobe, which was softened to the depth of half an inch. The part of the tumor posterior to the petrous bone, and beneath the tentorium, was somewhat smaller and less prominent than that just described in the middle cerebral fossa, was wholly confined to the interior surface of the dura mater, and must have almost entirely arrested the circula- MALIGNANT DISEASE OF TUB EAR. 407 tion of tlie lateral sinus. The Avholc of the cerehral veins and sinuses were very much distentled with dark-colored blood, but there was no appearance of disease in any other part of the cerebral substance than the softened portion of the inferior lobe. On examining the tumor by the aid of the microscope, the harder portions were found to consist of very delicate fibres and nucleated cells, Avhile the softer parts and creamy fluid were almost wholly composed of nucleated cells, circular, fusiform, and angular. There appears every reason to believe that, in this case, the dis- ease originated in the tympanic cavity. It will have been seen that the seat of the pain when first complained of, was the car. This was followed by a growth from the meatus, similar to a polypus, and then by paralysis of the portio dura nerve. From this centre the disease seems to have spread in all directions, destroying every structure which it approached. In the preparation, a large portion of the osseous Avail of the cranium is seen to be absent, so that, by pressing upon the tumor during life, the contents of the cerebral cavity were also subject to pressure. Unfortunately in these cases, little can be done even to alleviate the sufferings of the patient. Local depiction by leeches applied to the vicinity of the tumor, hot fomentations and the administration of opiates, appear to be the only remedies capable of doing any service. It is nevertheless of the utmost importance to be able to decide upon the nature of the disease whenever it does occur, since measures Avill at least be re- frained from that are calculated to aggravate the disease, and no operation Avill be attempted. In the case in question, it is possible that the removal of part of the tumor, which was thought to be a polypus, did material injury, by causing the disease to advance more rapidly. Those Avho are careful will have no difiiculty in dis- tinguishing between an ordinary polypus growing from the walls of the meatus, and a portion of tumor similar to that of the case under discussion. The polypus is smooth and globular, and not covered by epidermis ; neither does it present an ulcerated surface, such as Avould be disclosed by a portion of encephaloid tumor when it exists and gives off secretion. Again, in cases of polypus growing from the external meatus, there is very rarely any tumefaction of the ear or integuments, such as is found in malignant disease. The ob- servation, so frequently made by me, may here be repeated, that as polypoid growths are so often symptomatic of the existence of irri- tation within the tympanic cavity, aiul are sometimes coexistent 408 THE DISEASES OF THE EAR. with disease of the bone, great caution shouUl always be used pre- vious to ])roceeding to extirpation. By referring to a very interest- ing case of malignant disease of the ear, published by Mr. AVilde at page 20G of his treatise on Aural Surgery, it will be found that he also lays much stress upon the necessity of being careful " in med- dling with morbid growths of long standing, without being fully satisfied as to their nature, and the place from which they grow." The cause of death in the patient whose case has here been con- sidered, appears to have been congestion of the brain, produced by the pressure of the tumor on its substance, as well as upon the lateral sinus. The second preparation illustrative of the effects of malignant disease of the ear extending to the brain, Avhich has to be described, was laid before the Pathological Society of London, in 1850, by Mr. Cooper Forster, to whom I am indebted for the specimen. The particulars, copied from the Transactions of the Pathological So- ciety, are as follow : — "• A strumous lad, aged 19, was knocked down by a cab nineteen months before his death, and struck on the right side of his head. He soon afterwards became deaf, and suffered severe pain in the right ear ; the part became slightly swollen and excessively tender, especially over the mastoid process. The swelling did not increase, but the pain in the head was most intense, and paralysis of the right portio dura nerve took place. No great change occurred until within the last six months, when, from another blow on the same spot, the disease seemed to become more active ; the side of the head, from above the temporal ridge to two inches below the ear, became enormously enlarged and tender ; and the external ear ap- peared as though pushed away from the side of the head. He ex- perienced great difficulty in swallowing solid food, and was also unable to speak. " About two months before his death, the swelling began to fun- gate and slough, profuse hemorrhage occurred at intervals, and sloughing very rapidly took })lace, and at last laid bare the pharynx. To such an extent, ultimately, had the destructive action taken place, that a large chasm formed around the ear, leaving that organ completely isolated. Xo brain symptoms occurred. The profuse hemorrhage and constant drain of pus (juickly destroyed him. ^''Autopsy. — The brain appeared perfectly healthy except at the lower part of the right hemisphere, wliich was pulpy and very soft. MALIGNANT DISEASE OF THE EAR. 409 The softening was, without doubt, occasioned by the upward pres- sure of a hard scrofulous-looking mass, attached to the petrous portion of the temporal bone, through the intei'vention of the dura mater, from which it seemed to spring. The mass pressed upon the bone below, and appeared as though inclined to force its way down- wards, through the temporal bone, at the junction of the squamous Avith the petrous portion, a great part of the latter being completely absorbed. Some new bone had formed at the inner side, and the whole of the exterior was occupied by a sloughy nwss and carious bone (as seen below), the surrounding parts being very hypertrophied ; no vestige of meatus or mastoid cells could be discovered ; the lateral sinus was filled by a coagulum." Fig. ion. ^-1:; From the history of the case just cited, and an examination of the preparation, there is no doubt on my mind but that the nature of the disease was malignant, very probably encephaloid, and that it commenced in the tympanic cavity. It will have been observed, that the early symptoms indicated that the disease was in the ear, both by the pain experienced there, and by the presence of deaf- ness. If the preparation be carefully inspected, it Avill be seen that 410 THE DISEASES OF THE EAR. the largest amount of destruction, and the most marked appearance of disease, are around the tympanic cavity ; from which the progress seems to have been downwards to the pharynx, upwards to the outer surface of the squamous bone, and histly, inAvards and up- wards to the cavity of the skull. The orifice communicating between the disease without and that within, is, however, very small in com- parison to the extent of the disease externally, and the internal surface of the bone is much less affected than the outer. That the disease was malignant is shown, I think, by the bleeding and fungoid character of the soft growth, and tlie peculiar expanded and spicu- lated state of the bone. The third case is one published in the eleventh volume of the Edinburgh Medical and Surgical Journal, by Mr. Wishart, and called by him a case of fungus hfcmatodes. The subject was a child three years old, in whom, after suffering for some weeks from severe pain in the right ear, followed by discharge, a tumor appeared surrounding the ear, and which speedily ulcerated, discharging a large quantity of fetid bloody matter ; hemorrhage also fre(|uently occurred. The child died within fifteen weeks after the appearance of the disease. On a post-mortem examination, the tumor was found to be as large as the child's head ; externally it had caused the destruction of the condyloid process of the lower jaw ; the zygomatic process was also gone. The tumor had advanced inwards, destroying the whole of the petrous bone, and extended upwards, through a large orifice in the squamous bone, so as to form a de- pression on the middle lobe of the brain, which was in other respects quite sound. As bearing upon the subjent, I may as well give briefly the par- ticulars of a case of disease of the petrous bone which occurred in the practice of Mr. Part, of Camden Town, to whom I am indebted for the preparation. The patient was a clergyman, aged twenty- five, subject for five years to a discharge from the right ear, with occasional pain. A year before his death an abscess broke behind the ear, wliich discharged at times. About a fortnight before his death he suftercd from severe pain in the head and vomiting, and had paralysis of tlie right ])ortio dura nerve. lie was not relieved by Jvny treatment, and the head-symptoms increased until his death. On a post-mortem inspection, a cavity was found in front of the ear, and another beneath the temporal muscles ; both contained a soft caseous substance. Tlie whole of the petrous bone, a portion of the MALIGNANT DISEASE OF THE EAR. 411 basilar process of the occipital and of the sphenoid, were found de- generated into a soft cheesy mass. The malar bone was destroyed, and the mastoid process occupied by the disease. The ventricles contained three ounces of bloody serum ; the arachnoid was much injected ; while between it and the pia mater was a layer of very yellow pus, extending along the base of the brain. In the middle lobe of the brain was an abscess containing upwards of an ounce of very fetid greenish pus ; and a second abscess existed in the middle of the posterior lobe. If the preparation be examined, as in the preceding cases, there will be found to be a large aperture in the squamous bone, and the petrous and mastoid bones are wholly con- verted into the white cheesy-looking matter. On examination by the microscope, this matter is discovered to consist of cells, varying in form, only few of which have any distinct nuclei ; granular matter is also interspersed among the cells. The case may be con- sidered as one of degeneration of the petrous bone, originating in the tympanic cavity. The ulceration at times proceeds most rapidly, extending to the bone, which is soon destroyed. Sometimes the greater part of the squamous bone disappears. A case of the kind has been published by Dr. Russell, of Birmingham, in the Association Journal, for March 31st, 1852, of which I will give a few particulars. Mrs. P., aged 66, was attacked, about nine months before her de- cease, Avith pain in the right ear, attended with swelling. A fort- night afterAvards, she struck it against a bracket ; the swelling broke, and the ear discharged. The discharge and pain continued, and paralysis of the portio dura ensued, while the power of hearing dis- appeared. xVt the time she was seen by Dr. Russell, there was in- tense pain in the ear ; mania, coma, and ultimately death, ensued. There was no history of early disease in the ear, but she had been accustomed to pick it with a pin, for a certain degree of itching. On an autopsy, tlie entire S(|uamous portion of the temporal bone was found to have been destroyed, and tlic disease had encroached upon the mastoid process, laying open the cells. Tlu petrous bone was also almost entirely destroyed. The dura mater was not injured, except in one spot, where there was a sloughy opening, the size of a crown-piece. Opposite the orifice in the dura mater, the brain was in a state of suppuration ; and both ventricles were full of the ddbris of sloughy cerebral tissue. There were about two drachms of thin, purulent fluid at the base of the brain. This spe- 412 THE DISEASES OF THE EAR. cimen, which through the kindness of Dr. Russell I had an oppor- tunity of inspecting, presented a very similar appearance to the one previously described. In each case all vestiges of the tympanic cavity had disappeared. They differ from the great majority of cases of disease in the tympanum, in extending outwards instead of upwards. The treatment in these cases consists in diminishing the symptoms of congestion of the brain, by the occasional application of leeches, and in attempting to allay the pain by the administration of mor- phia. CHAPTER XVIII. ON THE DEAF AND DUMB. DISEASES PRODUCING DEAF-MUTISM — THE CONDITION OF THE EARS IN THE DEAF AND DUMB, AS ASCERTAINED BY EXAMINATION DURING LIFE — THE CONDITION OF THE EAR IN THE DEAF AND DUMB, AS REVEALED BY DISSECTION — THE MODE OF EXA- MINING A CHILD SUPPOSED TO BE DEAF AND DUMB ON THE MEDICAL TREATMENT OF THE EARS OF THE DEAF AND DUMB — THE AMOUNT OF HEARING POSSESSED BY CHILDREN USUALLY ACCOUNTED DEAF AiND DUMB — ON THE EDUCATION OF THE DEAF AND DUMB; WITH CASES. TuE number of deaf-mute children examined, and from whom the facts in this chapter were obtained, amounted to 411. Of these, 313 were congenital cases, and 98 were the eflfect of different dis- eases acquired subsequent to birth. I. THE DISEASES PRODUCING DEAF-MUTISM. On the causes producing congenital deaf-mutism I am unable to oifer a decided opinion ; but the results of dissection, as detailed in a subsequent part of this chapter, show that the nervous apparatus is very frequently affected. If regard be also paid to the other cases I shall refer to, and the non-appearance of an efficient cause of any other kind, together with the analogy to be drawn from the cases in the chapter on Nervous Deafness, it would be no very violent assumption to suppose that early derangement of the nervous apparatus is at the root of most of the instances of deaf-mutism. Of the causes of acquired deaf-mutisra a more accurate estimate may be formed. Thus in the 98 cases of acquired deafness the causes were as follows : — Scarlet Fever 30 Fever, 23 Measles, ............. 4 Various diseases, as teething, convulsions, hydrocephalus, a full, fits, a fright, Ac, 35 98 414 THE DISEASES OF THE EAR. II. THE CONDITION OF THE EARS IN THE DEAF AND DUMB, AS ASCERTAINED BY EXAMINATION DURING LIFE. The condition of the ears in the deaf and dumb is very various, and in the majority of the ears there is some abnormal appearance, although it is often very slight. Thus, in only 197 out of 411 patients were the ears healthy. The following table shows the con- dition of those ears that were not healthy: — In GQ the surface of the membrana tympani was dull. 38 the membrana tympani was opaque. 12 the membrana tympani was more concave than natural. 3 the membrana tympani was very concave and opaque. 1 the membrana tympani was shrivelled. 10 the mem])rana tympani had fallen inwards. 9 the membrana tympani was perforated. 18 the membrana tympani was absent, from ulceration. 2 the meatus was full of cerumen. 35 the meatus was full of cerumen, and the membrana tympani opaque. 3 the meatus externus formed a cul-de-sac half an inch from the orifice. 1 the meatus contained a polypus. 3 the membrana tympani of one ear was opaque, and in the other it had fallen inwards. 2 the membrana tympani was opaque in one car and absent in the other. 1 the membrana tympani was normal in one ear and absent in the other. 3 the membrana tympani was fallen in in one car and perforated in the other. 1 the membrana tympani was natural in one ear and the meatus full of cerumen in the other. 1 the meml)rana tympani was fallen in in one car and dull in the other. 1 the membrana tympani was absent in one ear and the meatus contained a polypus in the other. 1 the membrana tympani was very concave in one ear and had fallen inwards in the other. ON THE DEAF AND DUMB. 415 In 1 the membrana tympani was natural in one ear and very con- cave in the other. 1 the memhrana tympani was perforated in one ear and opaque in the other. 1 the membrana tympani was very concave in one ear and absent in the other. It is interestinjr to observe the difference between the condition of the ears in the acquired and congenital cases. The condition of the ears in the 313 congenital cases : — 172, or nearly three-fifths, had a natural appearance. In the 172 cases of absolute deafness the folloAving was the con- dition of the ears : — 96 had a healthy appearance. In 37 each membrana tympani was dull. 20 there was an accumulation of cerumen, and each membrana tympani Avas dull. 12 each membrana tympani was opaque. 1 each membrana tympani had been destroyed by ulceration. 2 one membrana tympani was opaque, the other had fallen in. 1 one membrana tympani Avas opaque, the other Avas absent. 1 one membrana tympani Avas natural, the other Avas opaque. 1 one membrana tympani was natural and the other was absent. 1 one membrana tympani Avas fallen in and the other was per- forated. 172 The following was the condition of the ears in the 141 congenital cases, in Avhich certain sounds Avere heard : — [a.) In 11 Avho heard a clapping of the hands, 7 had a normal aspect. In 2 each membrana tympani Avas opaque. 1 each meatus was distended by cerumen, and the membrana tympani Avas opaque. 1 each membrana tympani Avas concave. 416 THE DISEASES OF THE EAR. (6.) In the 44 who heard a shout : — 21 "vvere apparently natural. In 7 each inembrana tympani ■was dull. 4 " " " " and the meatus full of cerumen. 4 " " " opaque. 4 " " " concave 2 " " " concave and opaque. 2 " " " perforated. (('.) In the 30 -who heard a loud voice : — 24 were apparently normal. In 7 each membrana tympani was dull. 3 " " " " and the meatus full of cerumen. 3 " " " opaque. 1 " " " concave. 1 in one car the membrana tympani was normal ; in the other it was opaque, and the meatus full of cerumen. ((?.) In the 43 who heard the vowels and repeated them after me: — 24 appeared to be normal. In G each membrana tympani was dull. 5 " " " " and the meatus was full of cerumen. 5 " " " opaque. 1 " " " concave and opaque. (r.) In the 5 who heard words and repeated them: — 2 appeared normal. In 1 each membrana tympani was dull. 1 " " " " and the meatus was full of cerumen. 1 in one ear the membrana tympani was opaque and concave, ani Foreign Medico-Chir. Review, July, 1857. ' with the progress of modern science. It is Ihe best Dr. Budil's Trealise on Diseases of the Liver is ^"^'^ "" Diseases of the Liver in any language.— now a standard work in Medical literature, and dur- London Med. Times and Gazette, June 27, ie57. ing the mtcrvals which have elapsed between the This work, now the standard book of reference on successive editions, the author has incorporated into i the diceases of which it treats, has been carefully the text the most striking novelties which have cha- I revised, and many new illustrations of the views of racterized the recent progress of hepatic physiology [ the learned author iidded in the present edition. — and pathology; so thataltliough the size of the book Dublin Quarlerlt/ Journal, Aug. 1&57. BY THE SAME AUTHOR. ON THE ORGANIC DISEASES AND FUNCTIONAL DISORDERS OF THE STOMACH. In one neat octavo volume, extra cloth. $1 50. BUCKNILL (J. C), M. D., Medical Superintendent of the Devon County Lunatic Asylum; and DANIEL H. TUKE, M. 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It has passed through several editions in order to The profession of this country, and perhaps also keep pace with the rapidly growing science of Phy- of E urope, have anxiously and for some time a waited siology. Nothing need be said in its praise, for its the announcement of this new edition of Carpenter's merits are universally known; we have nothing to Human Physiology. His former editions have for say of its defects, for they only appear where the many years been almost the only text-book on Phy- BCience of which it treats is incomplete. — Western, siology in all our medical schools, and itscircula- Lancet. j tion among the professiim has been unsurpassed by Themostcompleteexpositionof physiology which ' any work in any department of medical science, any language can at present eivo.— Brit, and For. ^' »» quite unnecessary for us to speak of this Med.-clirurg. Review. I work as its merits would justily. The mere an- nouncement of its appearance will afford the highest The greatest, the most reliable, and the best book pleasure to every student of Physiology, while its on the subject which we know of in the English perusal will be of infinite service in advancing language. — Stethoscopt. | physiological science. — Ohio Med. and Surg. Joum. BY THE SAMK AUTHOR. PRINCIPLES OF COMPARATIVE PHYSIOLOGY. New American, from the Fourth and Revised London edition. In one large and liandsome octavo volume, with over three hundred beautiful illustrations, pp. 752. Extra cloth, $4 80 ; leather, raised bands, S5 25. The delay which has existed in the appearance of this work has been caused by the very thorough revision and remodelling which it has undergone at the hands of the author, and the laree number of new illustrations which liave been prepared for it. It will, therefore, be found almost a new work, and fully up to the day in every department of the subject, rendering it a reliable text-book for all students engaged in this branch of science. Every effort has been made to render its typo- graphical finish and mechanical execution worthy of its exalted reputation, and creditable to the mechanical arts of this country. This book should not only be read but thoroughly studied by every member of the profession. N«me are too wise or old, to be benefited thereby. But especially to the younger class would we cordially Commend it as best fitted of any work in the English language to qualify them for the reception and coin- pretiension of those truths which are daily being de- veloped in physiology. — Medical Counsellor. Without pretending to it, it is an encyclopfdia of the subject, accurate and complete in all respects — a truthl'ul retlecticm of the advanced state at which the science has now arrived. — Dublin Quarterly Journal o/ Medical Science. A truly magnificent work — in itself a perfect phy- siological study. — Ranking'! Abstract. This work stands without its fellow. It is one few men in Europe could have undertaken; it is one 1 no man, we believe, could have brought to so suc- cessful an issue as Dr. Carpenter. It required for its production a physiologist at once deeply read in the labors of others, capable of taking a general, critical, and unprejudiced view of those labors, and of combining the varied, heterogeneous m^lerials at I his disposal, so as to form an harmonious whole. We feel that this abstract can give the reader a very imperfect idea of the fulness of this work, and no idea of its unity, of the admirable manner in which , material has ueeu brought, from the most various sources, to ccmduce to its completeness, of the lucid- ity of the reasoning it contains, or of the clearness of^language in which the whole is clothed. Not the profession only, but the scientific world at large, must feel deeply indebted to Dr. Carpenter for this great work. It must, indeed, add largely even to his high reputation. — Medical Tirrus. AND SCIENTIFIC PUBLICATIONS CARPENTER (WILLIAM B.), M. D., F. R. S., Examiner in Physiology and Comparative Anatomy in the University of London. THE MICROSCOPE AND ITS REVELATIONS. With an Appendix con- taming the Applications of the Microscope to Clinical Medicine, iSrc. By F. G. Smith, M. D. Illustrated by lour hundred and thirty-four beautiful engravings on wood. In one large and very handsome octavo volume, of 724 pages, extra cloth, $4 00 ; leather, $4 50. Dr. Carpenter's position as a microscopist and physiologist, and his great experience as a teacher, eminently qualify him to produce w^hat has long been wanted — a good text-book on the practical use of the microscope. In the present volume his object has been, as stated in his Preface, " to combine, within a moderate compass, that information with regard to the use of his 'tools,' which is most essential to the working microsco|>ist, wilh such an account of the objects best fitted for his study, as might quality him to comprehend what he observes, and might thus prepare him to benefit science, whilst expanding and refreshing his own mind " That he has succeeded in accom- plishing this, no one acquainted with his previous labors can doubt. The great importance of the microscope as a means of diagnosis, and the number of microsco- pists who are also physicians, have induced the American publishers, with the author's approval, to add an Appendix, carefully prepared by Professor Smith, on the applications of the instrument to clinical medicine, together with an account of American Micro>eopes, their modifications and accessories. This portion of the work is illustrated with nearly one hundred wood-cuts, and, it is hoped, will adapt the volume more particularly to the use of the American student. Every care has been taken in the mechanical execution of the work, which is confidently pre- sented as in no respect inferior to the choicest productions of the London press. The mode in which the author has executed his intentions may be gathered from the following condensed s-ynopsis of the CONTENTS. [ntroduction — History of the Microscope. Chap. I. Optical Principles of the Microscope. Chap. II. Construction of the Microscope. Chap. III. Accessory Apparatus. Chap. IV. Management of the Microscope Chap. V. Preparation, Mounting, and Collection of Objects. Chap. VI. Microscopic Forms of Vegetable Life — Protophyles. Chap. VII. Higher Cryptoga- mia. Chap. VIII. Phanerogamic Plants. Chap. IX. Microscopic Forms of Animal Life — Pro- tozoa — Animalcules. Chap. X. Foraminifera, Polycystina, and Sponges. Chap. XI. Zoophytes. Chap. XII. Echinodermata. Chap. XIII. Polyzoa and Compound Tunicata. Chap. XFV. Molluscous Animals Generally. Chap. XV. Annulosa. Chap. XVI. Crustacea. Chap. XVII. Insects and Arachnida. Chap. XVIII. Vertebrafed Animals. Chap. XIX. Applications of the Microscope to Geology. Chap. XX. Inorganic or Mineral Kingdom — Polarization. Appendix. Microscope as a means of Diagnosis — Injections — Microscopes of American Manufacture. Those who are acquainted with Dr. Carpenter's previous writings on Animal and Vegetable Physio- logy, will fully understand how vast a store of know- ledge he is able to bring to bear upon so comprehen- sive a subject as the revelations of the microscope ; and even those ■who have no previous acquaintance with the eonstruetion or uses of this instrument medical work, the additions by Prof. Smith give it a positive claim upon the profession, for which we doubt not he will receive their sincere thanks. In- deed, we know not where the student of medicine will find such a complete and satisfactory collection of microscopic facts bearing upon physiology and practical medicine as is cimtained in Prof. Smith's will find abundance of information conveyed in clear { appendix; and this of itself, it seems to us, is fully and simple language. — Med. Times and GazeUe. [ wortJi the cost of the volume. — Louisville Medical Although originally not intended as a strictly! Review , N ov . 1856 . BY THE SAME AUTHOR. ELEMENTS (OR MANUAL) OF PHYSIOLOGY, INCLUDING PHYSIO- LOGICAL ANATOMy. Second American, from a new and revised London edition. With one hundred and ninety illustrations. In one very handsome octavo volume, leather, pp. 566. S3 GO. In publishing the first edition of this work, its title was altered from that of the London volume, by the substitution of the word " Elements" for that of " Manual," and with the author's sanction the title of " Elements" is still retained as being more expressive of the scope of the treatise. To say that it is the best manual of Physiology | Those who have occasion for an elementary trea- now before the public, would notdo sufficient justice i tise on Physiology, cannot do better than to possess to the author. — Buffalo Medical Journal. themselvesofthemanual of Dr. Carpenter. — Medical In his former works it would seem that he had Examiner. exhausted the subject of Physiology. In the present. The best and most complete expose of modern hegives the essence, as it were, of the whole. — N. Y.\ Physiology, in one volume, extant in the English Journal of Medicine. \ language. — St. Louis Medical Journal. BY THE SAME AUTHOR. (Preparing.) PRINCIPLES OF GENERAL PHYSIOLOGY, INCLUDING ORGANIC CHEMISTRY AND HISTOLOGY. With a General Sketch of the Vegetable and Animal Kingdom. In one large and very handsome octavo volume, wilh several hundred illustrations. The subject of general physiology having been omitted in the last editions of the author's " Com- parative Physiology" and "Human Physiology," he has undertaken to prepare a volume which shall present it more thoroughly and fully than has yet been attempted, and which may be regarded as an introduction to his other works. BY THE SAME ATTTHOR. A PRIZE ESSAY ON THE USE OF ALCOHOLIC LIQUORS IN HEALTH AND DISEASE. New edition, with a Preface by D. F. Condie, M. D., and explanations of scientific words. In one neat 12mo. volume, extra cloth, pp. 178. 50 cents. ISIjAJNUHAlti; « JjJiA'S MiiUlUALi CONDIE (D. F.), M. D., Ac. A PRACTICAL TREATISE ON THE DISEASES OF CHILDREN. Fifth edition, revised and augmented. In one large volume, 8vo., leather, of over 750 pages. ^3 25. (Just Issued, 1859.) In presenting a new and revised edition of this favorite work, the publishers have only to state that the atithor has endeavored to render it in every respect "a complete and faithful exposition of the patholoiry and therapeutics of the maladies incident to the earlier stages of existence — a full and exact account of the diseases of infancy and childhood." To acccmplish this he has subjected the whole work to a careful and thorough revision, rewriting a considerable portion, and adding several new chapters. In this manner it is hoped that any deficiencies which may have previously existed have been supplied, that the recent labors of practitioners and observers have been tho- roughly incorporated, and that in every point the work will Ije found to maintain the high reputation it has enjoyed as a complete and thoroughly practical book of reierence in infantile affections. A few notices of previous editions are subjoined. Dr. Condie's scholarship, acumen, industry, and practical sense are manifested in this, as in nil his numerous contributions to science. — t)T. Holmes^s Hfport to the American Medical Association. Taken as a whole, in our judgment. Dr. Condie's Treatise is the one from the perusal of which the practitioner in this country will rise with the great- est satisfaction. — Western Journal of Medicine and Surgery. One of the best works upon the Diseases of Chil- dren in the English language. — Western Lancet. We feel assured from actual experience that no physicinn's library can be complete without a copy of this work.— iV. y. Journal of Medicine. We pronounced the first edition to be the best work on the diseases of children in the English language, and, notwithstanding all that has heen published, we still regard it in that light. — Medical Examiner. The value of works by native authors on the dis- eases which the physician is called upon to combat, will be appreciated by all ; anl the work of Dr. Con- die has gained for itself the character of a safe guide for students, and a useful work for consultation by those engaged in practice. — N. Y. Med. Times. This is the fourth edition of this deservedly popu- lar treatise. During the interval since the last edi- tion, it has been subjected to a thorough revision .^ ,, ,• . ■ , .. , , by the author; and all new observations in the ■^ItVil^ni^.rf/iitlVufJi^ZtL^P^nr-^ ^""^ therapeutics of children have been mori>.nn ino, 1/.0 ■ oiro „r^ Olito Mcdicul and includcd in tlie present volume. As we said btfore, to American medical literature Surgical Journal We feel persuaded that the American medical pro- fession will soon regard it not only as a very good, but as the very best "Practical Treatise on the Diseases of Children." — American Medical Journal. In the department of infantile therapeutics, the work of Dr. Condie is considered one of the best which has been published in the English language. — The Stethoscope, we do not know of a better book on diseases of chil- dren, and to a large part of its recommendations we yield an unhesitating concurrence. — Buffalo Med. Journal. Perhaps the most full and complete work now be- fore the profession of the United States; indeed, we may say in the English language. It is vastly supe- rior to most of its predecessors. — Transi/lvaniaMtd. Journal. CHRISTISON (ROBERT), M. D., V. P. R. S. E., Ac. A DISPENSATORY; or. Commentary on the Pharmacopoeias of Great Britain and the United States; comprising the Natural History, Description, Chemistry, Pharmacv, Ac- tions, Uses, and Doses of the Articles of the Materia Medica. Second edition, revised and im- proved, with a Supplement containing the most important New Remedies. With copious Addi- tions, and two hundred and thirteen large wood-engravings. By R. Eglesfeld Griffith, M. D. In one very large and handsome octavo volume, leather, raised bands, of over 1000 pages. $3 50. COOPER (BRANSBY BJ, F. R. S. LECTURES ON THE PRINCIPLES AND PRACTICE OF SURGERY. In one very large octavo volume, extra cloth, of 750 pages. $3 00. COOPER ON DISLOCATIONS AND FRAC- TURES OF THE JOINTS.— Edited by Brassbt B. Cooper, F. R. S., &c. With additional Ob- servations by Prof. J. C. Warren. A new Ame- rican edition. In one handsome octavo volume, extra cloth, of about 500 pages, with numerous illustrations on wood. $3 25. COOPER ON THE ANATOMY AND DISEASES OF THE BREAST, with twenty-five .Miscellane- ous and Surgical Papers. One large volume, im- perial 8vo.,' extra cloth, with 252 figures, on 38 plates. *2 50. COOPER ON THE STRUCTURE AND DIS- EASES OF THE TESTIS, AND ON THE THYMUS GLAND. One vol. imperial i-vo., ex- tra cloth, with 177 figures on 29 plates. £2 00. COPLAND ON THE CAUSES, NATURE, AND TREATMExNT OF PALSY AND APOPLEXY. In one volume, royal 12mo., extra cloth, pp.326. 60 cents. CLYMER ON FEVERS; THEIR DIAGNOSIS, PATHOLOGY, A.ND TREAT.MENT In one octavo volume, leather, of 600 pages. ?1 50. COLO.MBAT DE L'ISERE ON THE DISEASES OF FEMALES, and on the special Hygiene of their Sex. Translated, with many "Votes and Ad- ditions, by C. D. Meigs, M.D. Second edition, revised and improved. In one large volume, oc- tavo, leather, with numerous wood-cuts. pp. 720. S3 50. CARSON (JOSEPH), M. D., Professor of Materia Medica and Pharmacy in the University of Pennsylvania. SYNOPSIS OF THE COURSE OF LECTURES ON MATERIA MEDICA AND PHARMACY, delivered in the University of Pennsylvania. Second and revised edi- tion. In one very neat octavo volume, extra cloth, of 208 pages. $1 50. CURLING (T. B.), F. R.S., Surgeon to the London Hospital, President of the Hunterian Society, Ac. A PRACTICAL TREATISE ON DISEASES OF THE TESTIS, SPERMA- TIC CORD, AND SCROTUM. Second American, from the second and enlarged English edi- tion. In one handsome octavo volume, extra cloth, with numerous illustrations, pp. 4".>0. S2 00. AND SCIENTIFIC PUBLICATIONS. CHURCHILL (FLEETWOOD), M. D., M. R. I. A. ON THE THEORY AND PRACTICE OF MIDWIFERY. A new American from the fourth revised and enlarged London editioti. With Notes and Additions, by D. Francis UoNDiE, M. D., author of a "Practical Treatise on the Diseases of Children," &c. With 191 illustrations. In one very handsome octavo volume, leather, of nearly 700 large pages. $3 50. (Now Ready, October, ISGO.) This work has been so long an established favorite, both as a text-book for the learner and as a reliable aid in consultation ibr the practitioner, that in presenting a new edition it is only necessary to call atlention to the very extended improvements which it has received. Having had the benefit of two revisions by the author since the last American reprint, it has been materially enlarged, and Dr. Churchill's well-known conscientious industry is a guarantee that every portion has been tho- roughly brought up with the latest results of European investigation in all departments of the sci- ence and art of obstetrics. The recent dale of the last Dublin edition has not left much of novelty for the American editor to introduce, but he has endeavored to insert whatever has since appeared, together wilh such matters as his experience has ^hown him would be desirable lor the Amsrican student, including a large number of illustrations. Wilh the sanction of the author he has added in the lorm of an appendix, some chapters from a little -'Manual tor Midwives and Nurses," re- cently issued by Dr. Churchill, believing that the details there presented can hardly fail to prove of advantage to the junior practitioner. Tne result of all these additions is that the work now con- tains fully one-half more matter than the last American edition, with nearly one-half more illus- trations, so that nitwilhstanding the use of a smaller type, the volume contains almost two hundred pages more than before. No elfort has been spared to secure an improvement in the mechanical execution of the work equal to ihat which the text has received, and the volume is confidently presented as one of the handsomest that has tlnis far been laid before the American profession; while the very low price at which it is olfered should secure for it a place in every lecture-room and on every office table. A better book in which to learn these important The most popular work on midwifery ever issued poinls we have not met than Dr. Churchill's. Every page of it is full ot" instruction; the opinion of all writers of authority is given on questions of diffi- culty, as well !is tlie directions and advice ot the learned autiior himself, to which he adds the result of statibtical inquiry, putting statistics in tlieir pro per place and giving them their due weight, and no more. We have never read a book more free from professional jealousy than Dr. Churchill's. It ap- pears to be written with the true design of a hook on medicine, viz : to give all that is known on the sub- ject of which he treats, both theoretically and prac- tically, and to advance such opinions of his own as he believes will benefit medical science, and insure the safety of the patient. We have said enough to convey to the profession that this book of Dr. Chur- chill's is admirably Fuited for a book of reference for the practitioner, as well as a text-book for the student, and we hope it may be extensively pur- chased amongst our readers. To them we most Btrongly recommend it. — Dublin Medical Press, June 20, 1S60. To bestow praise on a book that has received such marked approbation would be superfluous. We need only say, therefore, that if the first edition was thought worthy of a favorable reception by the medical public, we can confidently affirm that this will be found much more so. The lecturer, the practitioner, and the student, may all have recourse to its pages, and derive from their perusal much in- terest anri instruction in everything relating to theo- retical and practical midwifery. — Dublin Quarterly Journal of Medical Science. A work of very great merit, and such as we can confidently recommend to the study of every obste- tric practitioner. — London Medical Gazette. This is certainly the most perfect system extant. It is the best adapted for the purposes of a text- book, and that which he whose necessities confine him to one book, should select in preference to all others. — Soutkem Medical and Surgical Journal. BY THE SAME AUTHOR. (Lately Puhlixlied.) ON THE DISEASES OF INFANTS AND CHILDREN. Second Araerican Edition, revised and enlarged by the author. Edited, with Notes, by W. V. Kkati.ng, M. D. In one large and handsome volume, extra cloth, of over 700 pages. $3 00, or in leather, S3 25. In preparing this work a second time for the American profession, the author has spared no labor in giving it a very thorough revision, introducing several new chapters, and rewriting others, while every portion of the volume has been subjected to a severe scrutiny. The efforts of the American editor have l)een directed to supplying such information relative to matters peculiar to this country as might have escaped the attention of the author, and the whole may, there- fore, be safely pronounced one of the most complete works on the subject accessible to the Ame- rican Profession. By an alteration in the size of the page, these very extensive additions have been accommodated without imduly increasing the size of the work. BY THE SAME AUTHOR. ESSAYS ON THE PUERPERAL FEVER, AND OTHER DISEASES PE- CULIAR TO WOMEN. Selected from the wrilingsof British Aiilhors previous to the close of the Eighteenth Century. In one neat octavo volume, extra cloth, of about 450 pages. $2 50. from the American press. — Charleston Med. Journal. Were we reduced to the necessity of having but tne work on midwifery, and jterinitted to choose, we would unhesitatingly take Churchill. — Western Med. and Surg. Journal. It is impossible to conceive a more useful and slegant manual than Dr. Churchill's Practice of Midwifery. — Provincial Medical Journal. Certainly, in our opinion, the very best work on he subject which exists. — N. Y. Annalist. No work holds a higher position, or is more de- serving of being placed in the hands of th'.- tyro, the advanced student, or the practitionei;. — Medical Examiner. Previous editions, under the editorial supervision of Prof R. M. Huston, have been received with marked favor, and they deserved it; but this, re- printed from a very late Dublin edition, carefully revised and brought up by the author to the present time, does present an unusually accurate and able exposition of every important particular embraced in the department of midwifery. * * Theclearn^£j directness, and precision of its teachings, together with the great amount of statistical research which its text exhibits, have served to place it already in the foremost rank of works in this department of re- medial science. — N. O. Med. and Surg. Journal. In our opinion, it forms one of the best if not the very best text-book and epitome of obstetric science which we at present possess in the English lan- guage. — Monthly Journal of Medical Science. The clearness and precision of style in which it is written, and the great amount of statistical research which it contains, have served to place it in the first rank of works in this departmentof medical science. —N. Y. Journal of Medicine. Few treatises will be found better adapted as a text-book for the student, or as a manual for the frequent consultation of the young practitioner. — American Medical Journal. 10 BLANCHARD & LEA'S MEDICAL CHURCHILL (FLEETWOOD), M . D., M . R, L A., fee ON THE DISEASES OF WOMEN; including those of Pregnancy and CiiUd- bed. A new American edition, revised by Ihe Author. With Notes and Additions, bv D Fran- cis CoNDiE, M. D., author ot "A Practical Treatise on the Diseases of Children." With nume- rous illustrations. In one large and handsome octavo volume, leather, of 768 pages. S.3 00. This edition of Dr. Churchill's very popular treatise mav almost be termed a new work, so thoroughly has he revised it in every portion. It will be found greatly enlarged, and completely brought up to the most recent condition of the subjeot, while the verv handsome series ol illustra- tions introduced, representing such pathological conditions as can be accurately portrayed, present a novel feature, and afford valuable assistance to the young practitioner. Such addiiions as ap- peared desirable for the American student have been made by the editor, Dr. Condie, while a marked improvement in the mechanical execution keeps pace with the advance in all other respects which the volume has undergone, while the price has been kept at the former very moderate rate. It comprises, unquestionably, one of the most ex- ' extent that Dr. Churchill does. His, indeed, is the act and comprehensive expositions of the present only thorough treatise we know of on the subject: state of medical knowledge in respect to the diseases and' it may he commended to practitioners and stu- of women that has yet been published.— jlwi. Journ. dents as a masterpiece in its particular department. Med. Sciences, July, 1657. —Thi Western Journal of Medicine and Surgery. This work is the most reliable which we possess As a comprehensive manual for students, or a on this subject; and is deservedly popular with the , work of reference for practitioners, it surpasses any profession.— CAnrieiion Med. Journal, July, 1857. other tliat has ever issued on the same subject from We know of no author who deserves that appro- the British press. — Dublin Quart. Journal. batioo, on "the diseases of females," to the same i DICKSON (S. H.), M. D., Professor of Practice of Medicine in the Jefferson Medical College, Philadelphia. ELEMENTS OF MEDICINE; a Compendious View of Pathology and Thera- peutics, or the History and Treatment of Diseases. Second edition, revised. In one large and handsome octavo volume, ol 750 pages, leather. $3 75. {Just Issued.) The steady demand which has so soon exhausted the first edition of this work, sufficiently shows that the author was not mistaken in supposing that a volume of this character was needed — an elementary manual of practice, which should present the leading principles of medicine with the practical results, in a condensed and perspicuous manner. Disencumbered of unnecessary detail and fruitless speculations, it embodies what is most requisite for the student to learn, and at the saiiie lime what the active practitioner wants when obliged, in the daily calls of his profession, to refresh his memory on special points. The clear and attractive style of the author renders the whole ea>-y of comprehension, while his long experience gives to his teachings an authority every- where acknowledged. Few physicians, indeed, have had wider opportunities for obser\-ation and experience, and lew, perhaps, have used them to better purpose. As the result of a long life de- voied to study and practice, the present edition, revised and brought up to the date of publication, will doubtless maintain the reputation already acquired as a condensed and convenient American text-book on the Practice of Medicine. DRUITT (ROBERT), M.R. C.S., fitc. THE PRINCIPLES AND PRACTICE OF MODERN SURGERY. A new and revised American from the eighth enlarged and improved London edition. Illustrated with four hundred and thirty-two wood-engravings. In one very handsomely printed octavo volume, leather, of nearly 700 large pages. $3 50. {Now Ready, October, 1560.) A work which like Druitt's Surgery has for so many years maintained the position of a lead- ing favorite with all classes of the profession, needs no special recommendation to attract attention to a revised edition. It is only necessary to state that the auilior has spared no pains to keep the work up to its well earned reputation of presenting in a small and convenient compass the latest condition of every department of surgery, considered both as a science and as an art; and that the services of a competent American editor have been employed to introduce whatever novelties may have escaped the author's attention, or may prove of service to the American practitioner. As several editions have appeared in London since the issue of the last American reprint, the volume has had the benefit of repeated revisions by the author, resulting in a very tnorough alteration and improvement. The extent of these addiiions may be estimated from the tact that it now contains about one-third more matter than the previous American edition, and that notwithstanding the adoption of a smaller type, the i)ages have been increa.sed by about one hundred, while nearly two hundred and fifty wood-cuts have been added to the former list of illustrations. A marked iiuprovement will also be perceived in the mechanical and artisiical execution of the work, which, printed in the I^est style, on new t\pe, and fine pajM?r, leaves little to be desired as regards external finish; while at the very low price allixed it will be found one of the cheapest volumes accessit)le to the profession. This popular volume, now a most comprehensive nothing of real practical importance has been omit- work in surgery, has undergone many corrections, ted; it presents a faithful epitomeofeveryihing re- improvements, and additions, and the principles and lating t > surgery up to the present hour. It is de- the practice of the art have been brought down to servedly a popular manual, both with the student the latest record and observation. Of the operations and practitioner.— Lcnt^on Lancet, Nov. 19, 11^59. in surgery it is inipoKsitile to (peak too highly. The t i • u- v. • /. • i defcripiionsare so char and concise, and the illus- '" closing this brief notice, we recommend as cor- trations so ascurale and numerous, that the student '''""^' »« "^^^ *•"« "'"*' useful and comprehensive can have no difficulty, with instrument in hand, and hand-book. It must prove a vast assibtance, not bcok bv his side, over the dead body, in obtaining ""'>" to the student of surgery, but also to the busy a proper knowledge and sufficient tact in this much Pmctitiooer whi may not have the leisure to devote neplectrddepiirimentofmedicaleducation.— /Jria'iA '"mBelf to the study of more lengthy volumes.— and Forrign Midico-ckirurg. Review, Jan. ISCO. London Med. Times and Gazette, Oct. 22, 1S59. In the present edition the author has entirely re- In a word, this eighth edition of Dr. Sruitl's wriiien many of the chapters, and has incorporated Manual of Surgery is all that the surgical student the various iraprovemenis and addiiions in modern or practitioner could desire. — Dublin Quarterly surgery. On carefully going over it, we find that Journal of Mtd. Sciences, Nov. 1659. AND SCIENTIFIC PUBLICATIONS. 11 DALTON, JR. (J. C), M. D. Professor of Pliysiology in tlie College of Physicians, New York. A TREx\TISE ON HUMAN PHYSIOLOGY, designed for the use of Students and Prart it loners of Medicine. With two hundred and fit'ty-foiir illustrations on wood. In one very beautiful octavo volume, of over 600 pages, extra cloth, $4 00 ; leather, raised bands, $4 25. (Just Issued.) This system of Physiology, both from the ex- cellence of the arrrtngement studiously observed throughout every page, and the clear, Im-id, and in- structive manner in which each subject is treated, promises to form one of the most generally received class-books in the Knglish languajie. It is, m fact, a most admirable epitome of all the really jmporlant discoveries thai have always been received as incon- testable truths, as well us of those wliich have been recently added to our stock of knowledge on this sub- ject. We will, however, proceed to give a few ex- i tracts from the book itself, as a specimen of its style and composition, and this, weconceive, will bequite sufficient to awaken a general interest in a work which isimmeasiirabl) superior in its details to the majority of those of the same class t'l which it be- longs. In its purity of style and elegance of com- position it m-iy safely take its place with the very best of our Knglish classics; while in accuracy of cte8cripti(m it is impossible that it could be surpass ed. In every line is beautifully shadowed forth the emanations of the poliBhcd scholar, whose rellec- tions are clothed in a garb as interesting as they are impressive; with the one predominant feeling ap- pearing to pervade the whole — an anxious desire to please and at the same time to instruct. — Dublin Quarterly Journ. of Med. Sciences, Nov. 1859. The work before us, however, in our humble judg- ment, is precisely what it purports to be, and will answer admirably the purpose for which it is in- tended. It is par excellence, a. text-book; and the best text-book in tl is department that we have ever Been. We have carefully read tlie book, and speak of its merits from a more than cursory perusal. Looking back upon the work we have just finished, we must say a word concerning the excellence of its illustrations. No department is so dependent upon good illustrations, and those which keep pace with our knowledge of the subject, as that of physiology. The wo charms to BY THE SAME AUTHOR. (A lieiO Editt07l.) NEW REMEDIES, WITH FORMULA FOR THEIR PREPARATION AND ADMINISTRATION. Seventh edition, with extensive Additions. In one very large octavo volume, leather, of 770 pages. $3 75. Another edition of the " New Remedies" having been called for, the author has endeavored to add everything of moment that has appeared since the publication of the last edition. The articles treated of in the former editions will be found to have undergone considerable ex- pansion in this, in order that the author might be enabled to introduce, as lar as practicable, the results of the subsequent experience of others, as well as of his own observation and reilection ; and to make the work still more deserving of the extended circulation with which the preceding editions ha%'e been favored by the profession. By an enlargement of the page, the numerous addi- tions have been incorporated without greatly increasing the bulk of the volume. — Preface. One of the most u8eful.of the author's works.— Southern Medical and Surgical Journal. Tills elaborate and useful volume should be found in every medical library, for as a book of re- ference, for physicians, it is unsurpassed by any other work in existence, and the double index for diseases and for remedies, will be found greatly to The great learning of the author, and his remark- able industry in pushing his researches into every source wlience informatiim is derivable, have enabled him to tlirow together an extensive mass of facts and statements, accompanied by full reference to authorities; which last feature renders the work practically valuable to investigators who desire tf enhance its value.— A'ew York Med. Gazette. examine the original papers.— r/ie American Journal of Pharmacy. ELLIS (BENJAMIN), M.D. THE MEDICAL FORMULARY : being a Collection of Prescriptions, derived from the writings and practice of many of the most eminent physicians of America and Europe. Together with the usual Dietetic Preparations and Antidotes for Poisons. To which is added an Appendix, on the Endermic use of Medicines, and on the use of Ether and Chloroform. The whole accompanied with a few brief Pharmaceutic and Medical Observations. Tenth edition, revised and much extended by Robert P. Tho.mas, M. D., Professor ol Materia Medica in the Philadelphia College of Pharmacy. In one neat octavo volume, extra cloth, of 296 pages. $1 75. BLANCHARD & LEA'S MEDICAL ERICHSEN (JOHN), Professor of i^urstery in University College, London, 4c. THE SCIENCE AND ART OF SURGERY; being a Treatise on Suhgical Inji-riks, IJisEASES. AM> OPERATIONS. New and improved American, from the second enlarged and carelullv revised London t-dilion. Illustrated with over four hundred engravings on wood. In one large and handsome ootavo volume, of one thousand closely printed pages, leather, raised bands. S4 50. (Just Issued.) The very di-iingnished favor with which this work has been received on both sides of the Atlan- tic has Biirnulated tlie author to render it even more worthy of the position which it has so rapidly attained as a standard authority. Every portion has been carefully revised, numerous additions have been made, and the most watchful care has been exercised to render it a complete exponent of the most advanced condition of surgical science. In this manner the work has been enlarged by about a hundred pages, while the series of engravings has been increased by more than a hundred, rendering it one of the most thoroughly illustrated volumes before the profession. The additions of tlie author liaviiig rendered unneces>ary most of the notes of the former American editor, but little has been added in this coinitry ; some few notes and occasional illustrations have, however, been introduced to elucidate American modes of practice. It Is, in our liumble judgment, decidedly the best step of the operation, and not desertine him until the book of the kind \n the Kn^lish language. Strange final issue of the case is decided. — Sethofcope. that just such books are noiopener produced by pub- | Embracing, as will be perceived, the whole snrgi- lic leacherf of surgery in lliis country and Great Britain Indeed, it is a matter of great astonishment, but no less true than a-^loMishing. that of the many workson surgery republished in this country wiiliin the last fifteen or twenty years as text-books for medical students, ihi' is the only one that even ap- proximates (o the fulfilment of the peculiar wants of youngmen jusi ciUering upon the study of this branch of the profession. — WaUrnJoxtr .of Med. aneil and correcteii London edition. With one himdred and ninety-seven illustrations. Edited !)v Robert Bridges, M. D. In one large royal 12mo. volnme, of (300 pages. In leather, $1 65; extra cloth, $1 50. {Jiixt Isaned.) The death of the author liavnig; placed the editorial care of" this work in the practised hands ol Drs. Bence Jones and A. \V. Hudrnan, everything ha< l)een done in its revision which experience could suggest to keep it on a level with the rapid advance of chemical science. The additions requisite to thi* purpose have Heces>ilated an enlargement of the page, notwithstanding which the work has been increased by about fifty pages. At the same time every care has been used to maintain its distinctive character as a condensed manual for the student, divested of all unnecessary detail or mere theoretical speculation. The additions have, of course, been mainly in the depart- ment of Organic Chemistry, which has made such rapid progress within the last few years, but yet equal attention has been bestowed on the other branches of the subject — Chemical Physics and inorganic Chemistry — to present all investigations and discoveries of importance, and to keep up the reputation of the volume as a complete manual of the whole science, admirably adapted for the learner. By the use of a small but exceedingly clear type the matter of a large octavo is compressed within the convenient and portable limits of a moderate sized duodecimo, and at the very low price affixed. It is otVered as one of the cheapest volumes before the profession. Dr. Fownrs' excellent work lias lieen universally recopnized everywhere in Ills own and this country, as the best elemenlHry treatise on chemistry in the English tongue, and is very generiillv ailnptcd, we believe, as the standard text book in all < urcolk'ses, both literary nnd Ecientific. — Charleston Med Journ. anc Itvieic, i*ept. 1859. A standard m.inual, which has long enjoyed the reputatimi of emtiodying much knowlediroin a small space. The author hasachieved the diflicult task of eondensation with masterly taot. His hook is con- cise without being dry, and brief without being too dogmatical or general. — Virginia Med. and Surgical Journal. The work of Ur. Fownes has long been before the public, and its merits have been I'uUy appreci- ated as the best text-book on chemistry now in existence. We do not, of course, place it in a rank superior to the ,,-orks of Brande, Graham, Turner, Gregory, or Gmelin, but we say that, as a work for stuclents, it is preferable to any of them. — Lon- don Journal of Medicine. A work well adapted to the wants of the student It is an excellent exposition of the chief cloctrines and factsof modernchemistry. The size of the work, and still more the condensed yet perspicuous style in which it is written, absolve it from the charges very properly ur^ed against most manuals termed popular. — Edinburgh Journal of Medical Science. FISKE FUND PRIZE ESSAYS —THE EF- FECTS OF CLI.MATE ON TaiJERCULOUS DISEASE. I!v EnwiN Lee, M. R. C S , London, and THK INFIATENCE OF PREGNANCY ON I THE DEVELOl'MEIMT OF TUBERCLES By Edward Wabken, M. D , of Edent.on, N. C. To- srether in one neat 8vo vnlume, extra cloth. SI 00. FRICK ON RENAL AFFECTIONS; their Diag- nosis and Pathology. With illustrations. One volume, royal ISmo., extra cloth. 75 cents FERGUSSON (WILLIAM), F. R. S., Professor of Surgery in Kind's Collea;e, London, &c. A SYSTEM OP PRACTICAL StlRaERY. Fourth American, from the third and enlarged London edition. In one large and beautifully printed octavo volume, of about 700 pages, with 393 handsome illustrations, leather. $3 00. GRAHAM (THOMAS), F. R. S. THE ELEMENTS OF INORGANIC CHEMISTRY, including the Applica- lions of the Science in the Arts. New and much enlarged edition, by He.nry Watts and Robert Bridgks, M. D. Complete in one large and handsome octavo voliime, of over SOO very large pages, with two hundred and thirty-two wood-cuts, extra cloth. $4 00. ^t*i^ Part II., completing the work from p. 431 to end, with Index, Title Matter, &c., may be had separate, cloth backs and paper sides. Price $2 50. From Prof. E. N. Horsford, Harvard College. \ afford to be without this edition of Prof. Graham's It has, in its earlier and less perfect editions, been Kleincnts.— Si/r/wian's /ottrnoZ, March, 1859. familiar to me, and the excellence of its plan and p^„,„ p^„^ ^^^j g;^^ ^ y. Free Academy. the clearness and completeness of its discussions, ™, " » have long been my admiration. . The work is an admirable one in all respects, and its republication here cannot fiil to exert a positive No reader of English works on this science can influence upon theprogressof science in thiscountry. GRIFFITH (ROBERT E.), M. D., &c. A UNIVERSAL FORMULARY, containing the methods of Preparing and Ad- ministering Ollicinal and other Medicines. The whole adapted to Physicians and Pharmaceu. lists. Seco.nd Edition, thoroughly revised, with numerous additions', by Robert P. Tho.mas, M. D., Profe>sor of Materia .Medica in the Philadelphia College of Pharmacy. In one large and handsome octavo volume, extra cloth, of er^O pages, double columns. S3 00; or in sheep, $3 25. It was a work requiring much per.severaiice, and This is a work of six hundred and fifty-one pages when published wa.« looked upon as by far the best work of its kind that had issued from the American pres.s. Prof Tlioma= has certainly "improved." as well as added lolliis Formulary, and has rendered ii additionally deserving of the confidence of pharma- ceutists and physicians. — Am. Journal of Pharmacy. We are happy to announce a new and improved edition of this, one of the most valuable and useful works that have e-naiiated from an American pen. embracing all on the su!>jeci of preparing and admi- iilslerine medicines that can he desired by the physi- cian ana pharmaceutist. — Wesiern Lancet. The amouiilof useful, every-day mauer.for a prac- ticiiie; physician, is really immense.— £ox/on Med. and Surg. Journal. This edition has been etreatU improved by the re- vision and ample a 'inguage. The additions amount of daily u-efuliiess to practitioners of medicine; it is to about seventy pairc«, and nc effort ha-; been spared euer adapted lo iheir purposes hai, ihe dispensaio- . ,„ i,,^.,,,,,^ j,, ,^Vm all the recent improvemen Ties. — Southern Mtd. and Surg. Journal. work of this kind appears to u« indispensable to the Itis one of the most useful books a country practl- 1 physician, and ihere is none we can more cordially ioner can possibly have.— Jtferfi'cni CAro/iic.'*. ' recommend.— iV. Y. Journal of Medicine. ^ recommend.— iV. Y. Journal of Medicine. Iti BLANCHARD & LEA'S MEDICAL GROSS (SAMUEL D.), M. D., Professor of Surgery lu the Jeircrson Medical College of Philadelphia, &c. Just Issued. A SYSTEM OF SURGERY : Pathological, Diagnostic, Therapeutic, and Opera- tive. Illusiraled by Nine HuNnuED and Thirtv-six Engravings. In two larg-e and beautifully • printed octavo volume-, of aearl J' twenty-four hundred pages; strongly bound in leather, with rai»ed bands. I'rice $12. From the Author's Preface. " The object of this work is to furnish a syslematic and comprehensive treatise on the science and practice of siirpery, considered in the broadest sense; one that shall serve the practitioner as a faithful and availiibie guide in his daily routine of duty. It has been too much the custom of mod- ern writers on this department o( the healing art to omit certain topics altogether, and to speak ol others at undue length, evidently assuming that their readers could readily supply the deficiencies Irom other sources, or that what has been thus slighted is of no particular practical value. My aim has been to eml)race the whole domain of surgery, and to allot to every subject its legitimate claim to notice in the great family of external diseases and accidents. How far this object has been accom- plished, it is not for me to determine. It may safely be utiirmed, however, that there is no topic, properly appertaining to surgery, that will not be found to be discussed, to a greater or less extent, in these volmnes. If n larger space than is customary has been devoted to the consideration of mllammalion and its results, or the great princijiles of surgery, it is because of the conviction, grountled upon long and close observation, that there are no subjects so little understood by the general practitioner. Special attention has also been bestowed upon the discrimination of diseases; and an elaborate chapter has been introduced on general diagnosis." That these intentions have been carried out in the fullest and most elaborate manner is sufficiently shown by the great extent of the work, and the length of time during which the author has been concentrating on the task his studies and his experience, guided by the knowledge which twenty years of lecturing on surgical topics have given him of the wants of the profession. Of Dr. GroBs's treatise on Surgery we can say 1 At present, however, our object is not to review no more than that it is the most elaborate and com- the work (this we purpose doing hereafter), but pletf work on this branch of the I.eiiliiig art which simply to announce its appearance, that m the has ever been published in any country. A sys- j meantime our readers may procure aud examine it tcmatic work, it admits of no analytical review; i for themselves. But even this much we cannot do but, did our space pi-riiut, we should gladly give j without expressing the opinion tliat, in putting forth gome extracts from it, to enable our readers to judge thpse two volumes. Dr. Gross has reared for hira- of the c'assiciil style of the author, and the exhaust- I self a lasting monument to his skill as a surgeon, ing way in which each subject is trented. — Dublin ' and to his industry and learning as an author. — St. Quarterly Journal of Med. Science, Nov. 1859. I Louis Med. and Surg. Journal, Nov. 1S59. The work is so superior to its predecessors in j "With pleasure we record the completion of this matter and extent, as well as in illustrations and long-anticipated work. The reputation which the style of publication, that we can honestly recom- autlior has for mauv vears sustained, both as a sur- mend It as the best work of the kind to be taken | pe„n „nj „g ^ writerj had prepared us to expect a home by the young practitioner.—^;/!. Med. Joum., | treatise of great excellence aud originality; but we Jan. ISCO. confess we were by no means prepared tor the work The treatise of Prof. Gross is not, therefore, a I which is before us — the most complete treatiseupon mere te.xl-liook for undergraduates, but a systema- surgery ever published, either in this or any othtr tic record of more than thirty years' experience, I country, and we might, perhaps, safely say, the reading, and retlection by a man of observation, ! most original. There is no subject belonging pro- sound judgment, and lare practical tact, and as such j perly to surgery which has not received from the deserves to take rank with the renowned produc- I authoia due share of attention. Dr. Grots has sup- lions of a similar character, by Vidal and Boycr, of [ plied a want in surgical literature which has long France, or those of Ohelius, Blasius, and Langen- been felt by practitioners; he has furnished us with been, of (jerinany. Hence, we do not hesitate to a complete practical treatise upon sargery in all its departments. As .■Xmericins, we are proud of the achievement; as surgeons, we are most sincerely thankful to him for his extraord narv labors in our behalf— iV. Y. Monthly Review and Buffalo Med. Journal, Oct. 1S50. express the opinion that it will speedily take the same elev:ited position in regard to surgery that has been given by common consent to the masterly work of Pereira in Materia Medica, or to Todd and Bow- man in Physiology. — y. O. Med.amd Swg. Journal, Jan. IbGO. | BY THE SAMS AUTHOR. ELEMENTS OF PATHOLOGICAL ANATOMY. Third edition, thoroughly revi>ed mid greatly improved. In one large and very handsome octavo volume, with about three hundred and lif'ty U-autiful illustrations, of which a large numlier are from original drawings. I'rice in extra cloth, $J 75; leather, rai-sed bands, S!i 25. (Lately Piihli.^lied.) The very rapid advances in the Science of Pathological Anatomy during the last few years have rendered essential a thorough modification of this work, with a view of making it a correct expo- nent of the present state of the subject. The very careful manner in which this task has been executed, and the aiuount of alteration which it has undergone, have enabled the author to say thai " wilh the iiiniiy changes and iiTiprovements now introduced, the work may be regarded almost as a new treatise," while the etiorts of the atithor have l)een seconded as regards the mechanical execution of the volume, rendering it one of the handsomest productions o( the American press. We most sincerely congratulate the author on the , We have been favorably impressed with the gene- ■uccessfiil manner in w.'iich he has accomplished his ' ral manner in which Dr. Gross has executed his task propnied object. His book is most admirably cal- , of affording a comprehensive digest of the present Rulatrd to fill up a blank which has long been fi;lt to [ state of the literature of Pathological Anatomy , and exist in IliiH drp.-irtment of medical literature, and have much pleasure in recommending his work to as such must become very widely circulatetl amongst our readers, as we believe one well deserving of all clnHsrR of the profession. — Dublin <^iiar«er/y , diligent perusal and careful study. — Montreal Med. Joum. of Med. Science, Nov. 1857. j Ckron., Sept. 1657. BY THK SAMK AUTHOR. A PRACTICAL TREATISE ON FOREIGN BODIES IN THE AIR-PAS- SAGE^. Ill one handsome octavo volume, extra cloth, with illustrations, pp. 4t)8. $2 75. AND SCIENTIFIC PUBLICATIONS. 17 GROSS (SAMUEL D.), M. D., Professor of Surgery in the Jefferson Medical College of Philadelpliia, &c. A PRACTICAL TREATISE ON THE DISEASES, INJURIES, AND MALFORMATIONS OF THE UKINAKY BLADDER, THE PROSTATE GLAND, AND THE URETHRA. Second Edition, revised and much enlarg-ed, with one hundred and eighty- four illustrations. In one large and very handsome octavo volume, of over nine hundred pages. In leather, raised bands, $5 25; extra cloth, $4 75. Philos'ipliio.Tl in its design, metlKidiciil in its ar- i agree with us, that there is no work in the English rangement, simple and sound in its practical details, language which can make any just pretensions to it may in truth he said to leave scarcely anything to be its equal. — N. Y. Journal of Medicine . be desired on so important a subject.— Uosron Med. . a volume replete with truths and principles of the utmost value in the investigation of these diseases. - and SuTg Journal. Whoever will peruse the vast amount of valuable practical intormation it contains, will, we think, American MedicalJoumal . GRAY (HENRY), F. R. S., Lecturer on Anatomy at St. George's Hospital, London, &c. ANATOMY, DESCRIPTIVE AND SURGICAL. The Drawings by H. V. Carter, M. D., late Demonstrator on Anatomy at St. George's Hospital ; the Dissections jointly by the Author and Dr. Carter. In one magnificent imperial octavo volume, of nearly 800 pages, with 363 large and elaborate engravings on wood. Price in extra cloth, $6 25; leather raised bands, $7 00. (Just Issued.) The author has endeavored m this work to cover a more extended range of subjects than is customary in the ordinary text-books, by giving not only the details necessary for the student, but also the application of those details in the practice of medicine and surgery, thus rendering it both a guide for the learner, and an admirable work of reference (or the active practitioner. The ejigravings form a special feature in the work, many of them being the size of nature, nearly all original, and having the names of the various purls printed on the body of the cut, in place of figures of reference with descriptions at the foot. They thus form a complete and splendid series, which will greatly assist the student in obtaining a clear idea of Anatomy, and will also serve to refresh the memory of those who may find in the exigencies of practice the necessity of recalling the details of the dissecting room ; while combining, as it does, a complete Atlas of Anatomy, with a thorough treatise on systematic, descriptive, and applied Anatomy, the work will be found of essential use to all physicians who receive students in their offices, relieving both preceptor and pupil of much labor in laying the groundwork of a thorough medical education. The work before us is one entitled to the highest 1 to exist in this country. Mr. Gray writes through- praise, and we accordingly \veleome it as a valu- : out with both branches of his subject in view. His able addition to medical literature. Intermediate ^ description of each particular part is followed by a in fulness of detail between the treatises of S lar : notice of its relations to tie parts with which it is pey and of Wilson, its characteristic merit lies in i connected, and this, too, sufficiently ample for all the number and excellence of the engravings it | the purposes of the 0|>erative surgeon. After de- contains. Most of these are original, of much j scribing tlie bones and muscles, he gives a concise larger than ordinary size, and admirably executed, statement of the fractures to which the bones of The various parts are also lettered after the plan the extremities are most liable, together with the adopted in Holden's Osteology. It would be uiffi- amount and direction of the displacement to which cult to over-estimate the advantages offered by this the fragments are subjected by muscular action, mode of piciorial illusiratiun. Bones, ligaments. The section on arteries is remarkably full and ac- muscles, bloodvessels, and nerves are each in turn , curate. Not only is the surgical anatomy given to figured, and marked with their appropriate names; evjry important vessel, with directions for its liga- thus enabling the student to c( mpreliend,ata glance, tion, but at the end of the description of each arte- what would otherwise often be ignored, or at any rial trunk we have a useful summary of the irregu- rate, acquired only by prolonged and irksome ap- larities which may occur in its origin, course, and plication. In conclusion, we heartily commend the termination. — N. A. Med. Chir. Review, Mar. 1559. work of Mr. Gray to the attention of the medical profession, iVeling certain tliat it should be regarded as one of the most valuable contributions ever made to educational literature. — A'. Y. Monthly Review. Dec. 1859. In this view, we regard the work of Mr. Gray as far better adapted to the wants of the professiim, and especially of the student, than any treatise on anatomy yet published in this country. It is destined. we believe, to supersede \\[ others, both as a manual of dissections, and a standard of reference to the student of general or relative anatomy. — N. Y. Journal of Medicine, Nov. 1859. This is by all comparison the most excellent work on Anatomy extnnt. It is just the thin^ that has bc«n long desired by the profession. With such a euide as this, the student of anatomy, the practi- tioner of medicine, and the surgical devotee have all a newer, deirer, and more radiant light thrown npon the intricacies and mysteries of this wonder- ful tcience, and are thus enabled to accomplisli re- sults which hitherto seemed poscible only to the ■pecialist. The plates, which are copied Crom re- Mr. Gray's book, in excellency of arrangement and comnleteness of execution, e.xcteds any work on anatomy hitherto published in the English lan- guage, affording a complete view of the structure of the tiuman body, with especial reference to practical surgery. Thusthe volume constitutesa perfectbook of reference for the practitioner, dem.inding a place in even the most limited library of the physician or surgeon, and a work of nee ssity for the student to fix in his mind what he has learneil by the dissecting knife from the book of nature. — The Dublin Quar- terly Journal of Med. Sciences, Nov. 1858. In our judgment, the mode of illustration adopted in the present volume cannot but present many ad- vantages to the studentof anatomy. To the zealous disciple of Vesalius, eiirnestly desirous of real im- provement, the book will certainly be of immense value; but, at the same time, we must also confess that to those simply desirous of "cramming" it will be an undoubted eodsend. The peculiar value of Mr. Gray's mode of illustration is nowhere more markedly evident than in the chapter on osteology, and especially in those portions which treat of the cent dissections, are so well executed, that the most bones of the head and of th-ir development. The superficial observer cannot fail to perceive the posi gt^jy „f j|,pgg p.^^jg jg t,,ug „„^,|g „„g „f comparative ense, if notof positive pleasure : and those bugbears tions, relations, and distinctive features of the vari- ous parts, and to tnkf in more of anatomy at a glance, than by many long hours of diligent study over the most erudite treatise, or, perhaps, at the dissecting table itself. — Med.Journ. of N. Carolina, Oct. 1^59. For thi.s truly admirable work the profession is indebted to the distinguished author of "Gray on the Spleen." The vacancy it fills has been long felt if the student, the leinjioral and sphenoid bones, are shorn of half their terrors. It is, in our estimation, an admirable and complete text-book for the student, and a useful work of reference for the practitioner; its pictorial character forming a novel element, to which we have already sufficiently alluded. — Am. Journ. Med. Sci., July, 1859. 18 BLANUHAKD & LEA'S MEDICAL GIBSO.V'S INSTITL'TKS AND PRACTICE OF i 8URGKUV. Eirhih rditifin, improveil niid hI- tertd. With thirty-four platrs. In two handsome (Hrtavo volumti, containtnir iibuut 1,000 pages, leather, raised band 1. SO SO. GARDNKR'S MKUICAL CHKMISTRY, for the use of (Students and the Profi'Rsion. In one royal I2ino. vol., clotli, pp. :J90, with woodcuts. 91. UI.fUE'S ATL.\.S or PATHOi.OGICAL HIS- TOLOGY. Trar.8lutid, wilh Notes and Addi- tions, by Joseph Leidy, M. D. In one volume, very lar^e imperial quarto, extra cloih, wi'i320 cupper- plate hgures, plain and eolorcd, S5 00. HUGHES' INTRODUCTION TO THE PRAC- TICE OP AUSCL'LTAI'ION A.M/ OTHER .MODE!* OF PHYSICAL DIAGNOSIS IN DIS- EASES OF THE LUNGS AND HEART. Se- cond edition 1 vol. royal lamo., ex. cloth, pp. 304. 81 00. HAMILTON (FRANK H.), M. D., ProiVggor of Surpcry in the Uaivergity of BulTalo, &c. A PRACTICAL TREATISE ON FRACTURES AND DISLOCATIONS. In one lurjre and hQiidsome ocluvo volume, of over 700 pages, with 289 illuslralioiisi. SI 25. (Nou> litady, January, ISOO.) This is n valuable contribution to the surgery of ' illustrated, which will be a desideratum for those most important atTectitms.and is the more welcome, practitioners who cannot conveniently see the mo- inasmuch as at tlie prcstnt time we do not pi>8gcs» dels applied. — A'em Yorlt Med. Press, Feb 4, 1860. a siHRle complete treatue on Fraciurcs and Dislo- ^y^ rccard this work as an honor not i to be for an indefinite period of time Every surgeon, young and old, should possess When we say. however, that we believe it will at bimtelf of it, and give it a careful perusal, in drding an example of honest, well-directed, and rous and remarkable fur accuracy of delineutitm. uttiring industry in authorship which every surgeon The various mechanical appliances are faithfully may en.ulate.- Am. Med. Journal, April, 1860. HOBLYN (RICHARD D.), M. D. A DICTIONARY OF THE TERMS USED IN MEDICINE AND THE COLL.ATliKAL SCIENCES. A new American edition. Revised, with numerous Additions, by Isaac Hays, M. D., editor of the " Aniencnii Jotinial olthe Medical Sciences." In one large royul r.im<). volume, leather, of over OOO double columned pages. $1 SO. To both practitioner and stu,g „,p ,,^^, ,,„„k „( jeffnitions we have, and We know of no dictionary belter arranged and ought always to be upon the student's table. — •itapted. Itisnotincumbered with the obsoleteterms i Southtm Med. and Surg. Journal. of a bygone age, but it contains all that are now in ■ HOLLAND'S MEDICAL NOTES AND RE- FLECTIONS. From the Ihitd L.mdon edition. Id o6c handsome ocluvo volume, extra clo'.h. S:5. HORNER'S SPECIAL ANATOMY AND HIS- TOLOGY. Eighth edition. Extensivly revised and moditied. In two large octavo volc.mes, ex- tra cloth, of more than 1000 pages, with over 300 illustratiuna. S6 00. HABERSHON (S. O.), M. D., Assistant Physician to and Lecturer on .Materia .Mediea and Tlier;i|ieutics at Guy 's Hospital, 4c. PATHOLOGICAL AND PRACTICAL (HiSEUVATlONS ON DISEASES OF THE ALLMENTAHY CANAL, CESOPIIAGUS, STOMACH, C^CIJM. AND INTES- TINES. With illuslrniions on Wood. In one handsome octavo volume of 312 pages, extra cloth $\ 75. (A'otr Heady.) AND SCIENTIFIC PUBLICATIONS. 19 HODGE (HUGH L.), M.D., Professor of Mid%vifery and the Diseases of Women and Children in the University of Pennsylvania, &c. ON I)IS1':ASES peculiar to women, includintr Displacements of the Uterus. AVith orig'inal illustrations. In one beautifully printed octavo volume, of nearly 500 pages. {Now ReaUy.) The profession will look with much interest on a volume embodying the long and extensive ex- perience of Professor Hodge on an important branch of practice in which his opporinnilies for investigation have been so extensive. A short summary of the contents will show liie scope of the Work, and the manner in which the subject is presented. It will be seen that, with the excej)- tion of Displacements of the Uterus, he divides the Diseases peculiar to Women into iwo great conslilutionai classes — those arising from irritation, and those arising from sedation. CONTENTS. PART I. Diseases of Ikritation. — Chapter I. Nervous Irritation, and its Consequences — H. Irritable Uterus. — III. Local Symptoms of Irritable Uterus: Menorrhagia and Hsemorrhi-^ia; Leucorrho?a ; Dysnienorrhira — IV. Local Symptoms of Irritable Uterus; Complications. — V. General Symptoms of Irritable Uterus : Ccrebro-spniil Irritations. — VI. General Symptoms (if Irritable Uierus. — VII. Progress and Kesulis of Irritable Uterus. — VIII. Cau.>^es and Pathology of Irriiable Diseases — IX. Treatment of Irritable Uterus; Removal or Palliation of the Cause. — X. Treatment of Irritable Uterus: To Diminish or Destroy the Morbid Irritability — XI. Treatment of the Complications of Irritable Uterus. — XII. Treatment of the Complications of Irritable Uterus. PART II. Dispr.ACEMENTS OF THE Uteri:s. — Chapter I. Natural Position and Supports of the Uterus. — II. Varieties of Displacements of the Uterus, and their Causes. — III. Symptoms of Displacements of the Uterus. — IV. Treatment of Displacements of the Uterus. — V. Treatment of Displacements; Internal Supports. — VI. Treatment of Ditplacements ; Lever Pessaries — VII. Treatment of the Varieties of Displacements. — VIII. Treatment of Complications of Dis- placements of the Uterus. — IX. Treatment of Enlargements and Displacements of the Ovaries, &c. PART III. Diseases of Sedation. — Chapter I. Sedation and its Consequences: Organic and Nervous Sedation; Passive Congestion; Reaction; Treatment — II. Sedation of the Uterus; Amenorrhipa: Sedation of the Uterus from Moral Causes; Sedation of the Uterus from Physical Causes. — II [. Diagnosis and Treatment of Sedation of the Uterus. The illustrations, which are all original, are drawn to a uniform scale of one-half the natural size. JONES (T. WHARTON), F. R. S,, Professor of Ophthalmic Medicine and Surgery in University College, London, &c. THE PRINCIPLES iVND PRACTICE OF OPHTHALMIC MEDICINE AND SURGERV. With one hundred and ten illustrations. Second American from the second and revised London edition, with additions b/ Edward Hartshor.n'e, M. D., Surgeon to Wills' Hospital, &:c. In one large, handsome royal 12mo. volume, extra cloth, of SOU pages. $1 50. JONES (C. HAND FIELD), F. R. S., & EDWARD H. SIEVEKING, M.D., Assistant Physicians and Lecturers in St. .Mary's Hospital, London. A MANUAL OF PATHOLOGICAL ANATOMY. First American Edition, Revised. With three hundred and ninety-seven handsome wood engravings. In one large and beautiful octavo volume of nearly 750 pages, leather. S3 75. Aa a concise text-book, containing, in a condensed obliged to glean from a great number of monographs, form, a complete outline of what is Itnown in the and the field was so extensive that but few cultivated domain of Pathological Anatomy, it is perhaps the it with any dejrree of success. As a simple work best work in the Knglish language. Its great merit of reference, therefore, it is of great value to the consists in its completeness and brevity, and in this student of patholo|;ical anatomy, and should be in respect it supplies a great desideratum in our lite- , every physician's library. — Western Lancet. rature. Heretofore the student of pathology was 1 KIRKES (WILLIAM SENHOUSE), M. D., Demonstrator of Morbid Anatomy at St. Bartholomew's Hospital, A-c. A MANUAL OF PHYSIOLOGY. A new American, from the third and improved London edition. With two hundred illustrations. In one large and handsome royal r2mo. volume, leather, pp. 586. $2 GO. {Lately Published.) This is a new and very much improved edition of ' One of the very best handbooks of Phy8iw, without special details, silence, wliieli isnot so common or so clieapas prat- ! which are read with interest only by those who ^in^ people fancy. They have the gift of telling us \ would make a specialty, or desire to possess a criti- what we want to know, without thinking it neces- cal knowledge of the subject. — Ckarleston Med. sary to tell us all they know. — Boston Med. and j Journal. Surg. Journal. I 20 BLANCHARD & LEA'S MEDICAL LAVCOOK'S LKCTCRKS ON THE PRINCI- PLES AND METHODS OF MEDICAL OB- SERVATION AND RESEARCH. For the Use of Advanced Students and Junior Pniotitionerg. In one royal Vimo. volume, extra cloth. Price $1. KNAPP'S TECHNOI-OGY ; or, Chemistry applied to the Arts and to Manufactures. Edited hy Dr. Ro.NAi.Dn, Dr. RiciiAKbsoN, and Prof. \\ . R. JoHNso.N. In two hundsomr tivo. vols., with about SOU wood' engravings. gO 00. LALLEMAND AND WILSON. A PRACTICAL TREATISE ON THE CAUSES, SYMPTOMS, AND TREATMRNT OF SPEKMATORRHCEA. By M. Lalle.mand. Tran.Maled and edited by 11eni!Y.I M(l)orf;Ar.L. Third American fdition. To which is added ON DISEASES OF THE VESiCTL/E SEMINALES; and their associated organs. With special refer- ence to the Morbid Secretions of the Prostatic and Urethral Mucous Membrane. By Harris Wilson, M.D. In one neat octavo volume, of about 400 pp., extra cloth. $2 00. (Just Issued.) LA ROCHE (R.), M. D., &c. YELLOW FEVER, considered in its Historical, Pathological, Etiological, and Theru|)eutical Relations. Including a Skeldi of tiie Disease as it iias occurred in Philadelphia from I'iWto IS/j-l, with an examination of the connections between it and the fevers known under the same name in other parts of temperate as well as in tropical regions. la two large and handsome octavo volumes of nearly l-OOO pages, extra cloth. $7 00. nunt and unmana'jeable disease of modern times, has for several years been prevailing in our country to a greater extent than ever before; that it is no longer confined to either large or small cities, but penetrates country villages, plantations, and farm- houses; that it is treated with scarcely better suc- cess now than thirty or forty years ago; that there is vast mischief done by ignorant pretenders to know- ledge in regard to the disease, and in vie w of the pro- bability tliat a majority of southern physicians will be called upon to treat the disease, we trust that this able and comprehensive treatise will he very gene- rally read in the south. — Memphis Med. Recorder. From Professor S. II. Dickson, f'harleston, S. C, Sfplember 18, 1K55. A monument of intelligent and well applied re- ■eareli, almost without example. It is, indeed, in itself, a large library, and is destined to constitute the special' resort as a book of reference, in the lubjcct of which it treats, to all future time. We have not time at present, engaged as we are, by dai- and by night, in the work of combating this very disease, now prevailing in our city, to do more than give this cursory notice of what we consider as undoubtedly the most able and erudite medical publication our country has yet produced. But in view of the startlinu; fact, that this, the most malig- I BY THE SAME ATJ-^HOR. PNEUMONIA ; its Supposed Connection, Pathological and Etiological, with Au- tumnal Fevers, including an Inquiry into the Existence and Morbid Agency of Malaria. In one handsome octavo volume, extra doth, of 500 pages. $3 00. LUDLOW (J. L.), M. D. A MANUAL OF EXAMINATIONS upon Anatomy, Physiology, Surgery, Practice of Medicine, Ob.'^tetrics, Materia Medica, Chemistry, Pharmacy, and Therapeutics. To which is added a Medical Formulary. Third edition, thorousjhly revised and greatly extended and enlarged. With 370 illustrations. In one handsome royal 12mo. volume, leather, of 816 large pages, $2 00. The (Treat popularity of this volume, and the numerous demands for it during the two years in which It has been out o( print, have induced the author in its revision to spare no pains to render it a correct and accurate digest of the most recent condition of all the branches of medical science. In many resp«Tis it may. therefore, be regarded rather as a new book than a new edition, an entire section on Physiology having been added, as also one on Organic Chemistry, and many portions having I)een rcwritlen. A very complete series of illustrations has l>een introduced, and every care has t>cen taken in the mechanical execution to render it a convenient and satisfuciory book for study or reference. The arrangement of the volume in the form of (piestion and answer renders it especially suited for the olfice examination of students and for those preparing for graduation. We know of no better companion for the student I crnmmtd into his head by the various professors to during the hours spent in the lecture room, or to re- whom he is compelled to listen. — WesUm Lancet, fresh, at a glance, his memory of the various topics | May, 1857. LEHMANN (C. G.) PHYSIOLOGICAL CHEMISTRY. Translated from the second edition by Georoe E. Day, M. D., F. R. S., >.Vc., edited by R. E. Rogers, M. D., Professor of Chemistry in the Medical Department of the University of Pennsylvania, with illustrations selected from Fiinke's Atlas of Physiological Chemistry, and an Ap|)en(lix of plates. Complete in two large and handsome octavo volumes, extra cloth, containing 1200 pages, with nearly two hundred illus- trations. $t) 00. The work of I.rhmann stands unrivalled as the most coniprehenKi ve book of reference and informa- tion extant on every branch of the subject on which it ttcat*.— Edinburgh J oumnl of Medical Science. The most important contribution as yet made to Physiological Chemistry Am. Journal Med. Sci- ences, Jan. 1S56. BY THE SAME AUTHOR. (Tjiltfly Puhlishfd.) MANUAL OF CHEMICAL PHYSIOLOGY. Translated from the German, with Notes and Additions, by J. Cheston Morris, M. D., with an liilrodticlory Essay on Vital Force, by Professor Samiel Jackson, M. D., of the University o( Pennsylvania. With illus- trations on wood. In one very handsome octavo volume, extra cloth, of 336 pages. $2 25. Frctr. Pre/. Jaci'sou's Introductory Ex.^ny, In adopting the handbook of Dr Lehnmnn as a manual of Organic Chemistry for the use of the etudenls of the University, and in recommending his original work of Physiological Chemistry for their more mature studies, the high value of his researches, and the great weight of his autho- rity in that important department of medical science are fully recognized. AND SCIENTIFIC PUBLICATIONS. 21 LAWRENCE (W.), F. R. S., Slc. A TREATISE ON DISEASES OF THE EYE. A new edition, edited, with numerous additions, and 243 illustrations, by Isaac Hays, M. U., Surgeon to Will's Hospi- tal, &c. In one very lar^e and handsome octavo volume, of 950 pages, strongly bound in leather with raised bands. $5 00. MEIGS (CHARLES D.), M.D., Professor of Obstetrips, &c. in the .leflTerBon Medical College, Philadelphia. OBSTETRICS : THE SCIENCE AND THE ART. Third edition, revised and improved. With one hundred and twenty-nine illustrations. In one beautifully printed octavo volume, leather, of seven hundred and fifty-two large pages. $3 75. The rapid demand for another edition of this work is a sutTicient expression of the favorable verdict of the profession. In thus preparing it a third time lor the press, tne author has endeavored to render it in every respect worthy of the favor which it has received. To accomplish this he has thoroughly revised it in every part. Some portions have been rewritten, others added, new illustrations have been in many instances substituted for such as were not deemed satisfactory, while, by an alteration in the typographical arrangement, the size of the work has not been increased, and the price remains unaltered. In its present improved form, it is, therefore, hoped that the work will continue to meet the wants of the American prolession as a sound, practical, and extended System of Midwifery. Though the work has received only five pages of enlargement, its chapters throughout wear the im- pressof careful revision. E.xpunging and rewriting, remodelling its sentences, with occasional new ma- terial, all evince a lively desire that it shall deserve to be regarded as improved in maniier as well as matur. In the matter, every stroke of the pen has increased the value of the book, both in e.\pungings and additions — Western Lancet, Jan. 1857. The best American work on Midwifery that is accessible to the student and practitioner — N. W. Med. and Surg. Journal, Jan. lSo7. This is a standard work by a great American Ob- stetrician. It is the third and last edition, and, in the larguage of the preface, the author has '-brought the subject up to the latest dates of real improve- ment in our art and Science." — Nashville Journ. of Med. and Surg., May, 1857. BY THE SAME AUTHOR. {J/iSt Is.ilted.) WOMAN : HER DISEASES AND THEIR RE3IEDIES. A Series of Lee- tures to his Class. Fourth and Improved edition. In one large and beautifully printed octav© volume, leather, of over 700 pages. $3 60. In other respects, in our estimation, too much can- not be said in pr.iise of this work. It abounds with beautiful passages, and for conciseness, for origin- ality, and for all that is commendable in a work on the diseases of females, it is not excelled, and pro- bably not equalled in the English language. On the whole, we know of no woru on the diseases of wo- men which we can so cordially commend to the student iind practitioneras the one before us. — Ohio Med. and Surg. .Journal. The body of the book is worthy of attentive con- sideration, and is evidently the production of a clever, thoughtt'ul, and sagacious physician. Dr. Meigs's letters on the diseases of the external or- gans, contain many interesting and rare cases, and many instructive observations. We take our leave __ ^ _ of Dr. Aleigs, with a high opinion of his talents and Charleston Med. "Journal originality. — The British and Foreign Medico-Chi- ruTgical Revieio. Every chapter is replete with practical instruc- tion, and bears the impress of being the composition of an acute and experienced mind. There is a terse ness, and at the same time an accuracy in his de Full of important matter, conveyed in a ready and agreeable manner.— St. Lonis Med. and Surg. Jour. There is an off-hand fervor, a glow, and a warm- heartedness infecting the efr)rt of Dr. Meigs, which is entirely captivating, and which absolutely hur- ries the reader through from beginning to end. Be- sides, the book teems with solid instruction, and it shows the very highest evidence of ability, viz., the clearness with which the information is pre- sented. We know of no better test of one's under- standing a subject than the evidence of the power of lucidly explaining it. The most elementary, as well as the obscurest subjects, under the pencil of Prof. Meigs, are isolated and made to stand out in such bold relief, as to produce distinct impressions upon the mind and memory of the reader. — Tht Professor Meigs has enlarged and amended thi« great work, for such it unquestionably is, having passed the ordeal of criticism at home and abroao, but been improved thereby ; for in this new edition the author has introduced real improvements, and increased the value and utility of the book im- scription ot symptoms, and in the rules for diagnosis, Ljjeagurably. It presents so many novel, bright, which cannot fail to recommend the volume to the „„j sparkling thoughts; such an exuberance of new attention of the reader.— Ratik in g's Abstract. j jjg^g „„ almost every page, that we confess ouT- It contains u vast amount of practical knowledge. , selves to have become enamored with the book by one who has accurately observed and retained ! and its author; and cannot withhold tiur congratu- the experience of many years. — Dublin Quarterly lations from our Philadelphia confreres, that such a Journal. teacher is in their Bervice. — N. Y. Med. Gazett*. BY THE SAME AUTHOR. ON THE NATURE, SIGNS, AND TREATMENT OP CHILDBED FEVER. In a Series of Letters addressed to the Students of his Class. In one handsome octavo volume, extra cloth, of 365 pages. $2 50. The instructive and interesting author of this work, whose previous labors have placed his coun- trymen under deep and abiding obligations, again challenges their admiration in the fresh and vigor- ous, attractive and racy pages before us. it is a de- lectable book. * * « This treatise upon child- bed fevers will have an extensive sale, being des- tined, as it deserves, to find a place in the library of every practitioner who scorns tolag in the rear. — Nashville Journal of Medicine and Surgery. BY THE SAME AttTHOR ; WITH COLORED PLATES. A TREATISE ON ACUTE AND CHRONIC DISEASES OF THE NECK OF THE UTERUS. With numerous plates, drawn and colored from nature in the highest style of art. In one handsome octavo volume, extra cloth. $4 50. MAVNR'S DISPENSATORY AND THERA- PEUTICAL REME.MBRaNCER. Witheverv Practical Formula contiiined in the three British Pharmacopoeias. Edited, with the addition of the Formulae of the U. 3. Pharmacopoeia, by R. E. GKirriTHjM.D. 1 12mo. vol. ex. cl.,. 300pp. 75 c. MALGAIGNE'S OPERATIVE SURGERY.based on Normal and Pathological Anatomy. Trans- lated from the French by Frederick Brittan, A. B.,M. D. With numerous illustrations on wood. In one handsome octavo volume, extra cloth, of nearly six hundred pages. B'i 25. 22 BLANCHARD ic LEA'S MEDICAL. MACLISE (JOSEPH), SURGEON. SURGICAL ANATOMY. Forming one volume, very large imperial quarto. With -ixiy-eighi large and i^plendid PUiie>, drawn in the best style and beautilully colored. Con- taining one hundred and ninety Figure*, many of them the size of lile. Together with copious and explanatory letter-press. Strongly and handsomely bound in extra cloth, being one of the cheape-t and l)«,'st executed Surgical works as yet issued in this country. Sll 00. •,• The size ofthi* work prevents its transmi>sion through the post-olRce as a whole, but those who desire to have copies Ibrwarded by mail, can receive them in five parts, done up in stout wrappers. Pnw S^ 00. One of the (frratcit artistic triuiiiphi of the age A work which has no parallel in point of accu- in Surgical Anatomy.— BririsA American Medical racy and cheapness in the English language.— iV. y. Journal. Journal of Medicint. No praclitlonrr whn«r menns will admit should fail to piisums it. — Knnking's Abstract. T<"> much ciinnot tie suid in its praise; indeed, we havr not liineuiige to do it justice. — OMo Medi- cal and Surgical Journal. The most accurately engraved and beautifully colored pliiles we hiive ever seen in an American book — one of the hest and cheapest surgical works ever publishe>i('n to be specially called to a volume containing ihe experience of his long and extensive practice. The very I'avorable reception accorded to his " Treatise on Human Parturition," issued some years since, is an earnest that the present work will fulfil the author's intention of providing within a moderate compass a complete and trustworthy text-book for the student, and book of re- lerence for the practitioner. We congratulate the author that the task is done. ' tion to which its merits justly entitle it. The style We congru'iiluie him that he hasgiven to the medi- is such that the descriptionsare clear, and each sub- cal public a work which will secure for him a high ject is discussed and elucidated with due regard to anil permau'-nt position among the standard autho- its practical bearincrs, which cannot fail to make it rities on the principles and practice of obstetrics, acceptable and valuable to both students and prac- Conpralulaliiins are not less due to the medical pro- titioncrs. We cannot, however, close this brief fession of ihm C'luntry, on Ihe acquisilit but think that his book on thiidepartdieni of medicine. Kngaged for thirty- will find many readers and warm admirers wherever five years in an extended practice of uhstetrics, for obstetrics is tonight and studied as a science and an many years a teacher of this branch of instruction art. — TheCincinnati Lancttand Observer, Fe\).\65&. in one of the lar-.st of our institutions, a diligent ^ most respectable and valuable additi.m to our studentaswrlasacarefu observer, an originaland ^ome medical literature, and one reflecting credit independent thinker, wedded to no hohbies, ever „|,ke on the author and the institution to wnich he ready to consider witho.it prejudice new views, and jg attached. The student will find in this work a toadopt innovntionMf they arc really impr..ve.iients, most useful guide to his studies: the country prae- and withal a clear, agreeal.le writer, a practica. tiiioner, rusty in his reading, can obtain from its treatise from his pen could not fail to possess great p„„eg „ (^^f resume of the modern literature of the vn\ue. -Ruftalo Med Journal, Mrt. }bS8. scence; and we hope to see this American produc- In fact, this volumeniust take its place among the tion generally consulted by the profession. — Ya. ■tandard systematic treatises on obstetrics ; a posi- ' Med. Journal, Feb. 1868. MACKENZIE (WJ, M.D., Surgeon Oculist in Scotland in onlinary to Her Majesty, Ac. Ac. A PRACTICAL TREATISE ON DISEASES AND INJURIES OF THE EYE. To which is prefixed an Anatomical Introduction explanatory of a Horiziinlal Section ol the Human Eyeball, by Thomas Wharton Jonks, F. R. S. From the Fourth Revised and En- larged I.,oii(lon Edition. With Notes and Additions by Addinf.ll Hewson, AL D., Surgeon to Wills Hospital, Arc. i:c. In one very large and handsome octavo volume, leather, raised bands, with plates and numeroU!« wood-cuts. $•'3 '^5. The treatise of Dr. .Mackenzie indisputably holds ' able manner in which the author's stores of learning the first place, and forms, in respect of learning and and experience were rendered available lor general research, an Knryclop.Tdia unequalled in extent by use, at once procured l"or the first edition, as well on the cimiinent as in this country, that hich position as a standard work which each succesHive edition has more firmly established. We consider it the duty of evcrv one wlio has the love of hu profession and the welfare of his patient at heart, to make him- self familiar with this the most complete work in the English language upon the diseases of the eye. any other work of the kind, either English or foreign. — biroH on Di-'ttsfs of the Eft. Few mixirm books on any department of medicine or surgery have met with such extended circulation, or have procured for their authors a like amount of European celcliritv. The immense . :search wh.ch it displayed, the thorough acquaintance with the ">' tnglisii language upoi •abject, practically as well as •^- — 'ioally.and the'— ^"'- Titntsand liazettt AND SCIENTIFIC PUBLICATIONS. 26 MILLER (JAMES), F. R.S.E., Professor of Surgery in the University of Edinburgh, fee. PKINCIPLES OF SURGERY. Fourth American, from the third and revised Edinburgh edition. In one large and very beautilul volume, leather, of 700 pages, with two hundred and forty illustrations on wood. $3 75. The work of Mr. Miller is too well and too favor- ably known among us, as one of our best text-books, to render any further notice of it necessary than the announcement of a new edition, the fourth in our country, n proof of its extensive circulation among us. As a concise and reliable exposition of the sci- ence of modern surgery, it stands deservedly high — we know not its superior. — Boston Med. and Surg. Journal. The work takes rank with Watson's Practice of Physic; it certainly does not, fall bcliiiut tluit great work in soundness of principle or deplh of reason- ing and research. No physician w\n> v.ilues his re- putation, or seeks tlie interests of his clients, can acquit himself before his God and the world without m.iking himself familiar with the soand and philo- sophical views developed in the foregoing book. — I New Orleans Med. and Surg. Journal. BY THE SAME AUTHOR. {Jllst Issued.) THE PRACTICE OF SURGERY. Fourth American from the last Edin- burgh edition. Revised hy the Anierican editor. Illustrated by three hundred and sixty-four engravings on wood. In one large octavo volume, leather, of nearly 700 pages. $3 75. No encomium of ours could add to the popularity : his works, both on tlie principles nnive Additions, by Prof WiLLiA.M Procter, of the Philadelphia College of Pharmacy. In one handsomely printed octavo volume, extra cloth, oi 570 pages, wilh over 500 engravings on wood. $2 75. 24 BLANCHARD & LEA'S MEDICAL NEILL (JOHN), M. D., Surgeon to the Pennsylvania Hospital, 4c.; and FRANCIS GURNEY SMITH, M.D., Professor of Iiislitutcs of Medicine in the Pennsylvania Medical College. AN ANALYTKWL COMPENDIUM OF THE VARIOUS BRANCHES OK MEDICAL !?C1ENCE; for the Use ami Examination of Students. A new edition, revised and improved. In one very large and handsomely printed royal 12mo. volume, ol about one thousand pages, with 374 wood-cuts. Strongly bound in leather, with raised bands. $3 00. The very tiattering reception which ha« been accorded to this work, and the high estimate placed upon it by the profession, as evinced by the constant and increasing demand which has rapidly ex- hausted two large editions, have stimulated the authors to render the volume in its present revision more worthy o( the success which ha.s attended it. It has accordingly been thoroughly examined, and such errors as had on former occasions escaped observation have been corrected, and whatever additions were necessarv to maintain it on a level with the advance ofscience have been introduced. The extended .series of illu>trations has been still further increased and much improved, while, by a slight enlargement of the pjige, these various additions have been incorporated without increasing the bulk of the volume. The work is, therefore, again presentedaseminently worthy of the favor with which it has hitherto been received. As a book for daily reference by the student requiring a guide to his more elaborate text-books, as a manual for preceptors desiring to stimulate their students by frequent and accurate examination, or as a source /rom which the practitioners of older date may easily and cheaply acquire a knowledge of the changes and improvement in professional science, its reputation is permanently established. The best work of the kind with which we are ] the students is heavy, and review necessary for an acquninlrd. — Med. Examiner. examination, a compend is not only valuable, but Having made free use of this volume in our ex- I' '» alm.-st a sine qua non The one before us is, aminati.fns of pupils, we can speak from experi- "I ™?l°^"'^^'V^"'"«' '^* |""^' unexceptionable ence in r^com.iu-mling it as an admirable compend "f »" book* of the kind that we know of. The for students, and as especially useful to preceptors "e^est and soundest doctrines and the atest ira- who examine their pupils. It will save the teacher provements and discoveries are explicitly, though much labor by enal'liiig him readily to recall all of . concisely, laid before the student. There is a class the points upon whicTi his pupils should be ex- to whom we very sincerely commend this cheap book amined. A w..rk of this sort should be in the hands asworth its weight in silver-that class is thegradu- of every one who takes pupils into his office with a a'^« '» medicine of more than ten years' standing. vtewofVxaminln?them: and this isunquestionably who have not studied medicine since. They will the best of Its cUiiB.-Transylvania Med. Journal . \ perhaps find out from it that the science is not exactly now what it was when they left it off. — Tnt SutM- In the rapid course of lectures, where work for i scope. NELIGAN (J. MOpRE), M. D., M. R. I. A., &.C. {A spleitAid work. Just Issued.) ATLAS OF CUTANEOUS DISEASES. In one beautiful quarto volume, extra cloth, with splendid colored plates, presenting nearly one hundred elaborate representations of disea.se. $4 50. This beautiful volume is intended as a complete and accurate representation of all the varieties of Diseases of the Skin. While it can be consulted in conjunction with any work on Practice, it has especial reference to the author's " Treatise on Diseases of the Skin," so favorably received by the profession some years since. The publishers feel justified in saying that few more beautifully exe- cuted plates have ever been presented to the profession of this country. Nelignn's Atlas of Cutanenns Diseases supplies a ' give, at a toup d^cril, the remarkable peculiaritiea long existent desideratum much felt by the largest of each individual variety. And while thus the dii- class of our profession. It presents, in quarto size, ease is rendered more definable, there is yet no loss 16 plates, each containing from 3 to figures, and , of proportiivilU Journal of Medicine and Surgery . AND SCIENTIFIC PUBLICATIONS. 25 PARRISH (EDWARD), Lecturer on Practical Pharmacy and Materia Medica in tlie Pennsylvania Academy of Medicine, 4c. AN INTRODUCTION TO PRACTICAL PHARMACY. Designed as a Text- Book for the Student, and as a Guide for the Physician and Pharmaceutist. With many For- mulae and Prescriptions. Second edition, greatly enlarged and improved. In one handsome octavo volume of 720 pages, with several hundred Illustrations, extra cloth. $3 GO. (iVuM> Rearlij.) During the short time in which this work has been before the profession, it has been received with very great favor, and in assuming the position of a standard authority, it has filled a vacancy which had been severely felt. Stimulated by this encouragement, the author, in availing himself of the opportunity of revision, has spared no pains to render it more worthy of the confidence be- stowed upon it, and his assiduous labors have made it raiher a new book than a new edition, many portions having l/een rewritten, and much new and important matter added. These alterations and improvements have been rendered necessary by the rapid progress made by pharmacenticral science during the last few years, and by the additional experience obtained in the practical use of the volume as a text-book and work of reference. To accommodate these improvements, the size of the page has been materially enlarged, and the number of pages c).')0 pagec, ^trongly bound in leather, with raised bands; with sixty- four beauiilul Plates, and numerous Wood-cuts in the text, containing in all nearly two himdred large and beautiful figures. $.0 00. From Prof. Hod^$, of ike University of Pa. To the American public, it la moBt valiiiitile, from its intrinsic umlDuhted excellence, and as being the belt authorized exponent of Britisli Midwifery. Its circulation will, 1 trust, be extensive throughout oar country. It is unneeesBnrv to siiy anything in regard to the i truly elegnnt style in which they have brought it ntility <»f this work. It i's already u|iprfcmted in our i out, excelling themselves in its production, espe- couDtry for the value of the matter, the clearness of eiallv in its plates. It is dedicated to Prof. Meigs, Its style, and the fulness of its illustrations. To the and has the emphatic endorsement of I'rof. Hodge, physician's library it Is indispenKable, while to the as the best exponent of British Midwifery. We student as a ti-xt-book. from which to extract the knt.w of no text-book which deserves in all respects material for laying the foundation of an education on ' to he more highly recommended to students, and we obstetrical »ci.-nce, it has no superior.— OAio JVfed I could wish to see it in the handsof every practitioner, anti Surg. Journal. I for they will find it invaluable for reference.— 3fed. The publishers have secured its success by the I i****"*' RICORD (P.), M. D. A TREATISE ON THE VENEREAL DISEASE. By John Hunter, F. R. S. With oojiious Additions, by Ph. Kicord, M. D. Translated and Edited, with Notes, by Fref.mam J. BiwsTF.AD. M. D , Lecliirer on Venereal at the College of Physicians and Surgeons, New York. Second editiin, revised, coiilaining a re.-nime of Ricord's Recent Lectures o.n Chancre. In one handsome octavo volume, extra cloth, or.'J50 pages, with eight plates. $3 25. {Just Issued.) In revising this work, the editor has endeavored to introduce whatever matter of interest the re- cent inve>tigaiions of syphilographers have added to our knowledge of the subject. The principal Kource from which this has been derived is the volume of "Lectures on Chancre," publi>lied a few months since by M. Ricord, which ntl'oids a large amount of new and instructive material on many controverted pi>iiits. In the previous edition, M. Ricord's additions amounted to nearly one-third of the whole, and with the mailer now introduced, the work may be considered topreseul his views nnd experience more thoroughly and completely than any other. oecretaries, sometimes accredited and sometimes not. In the notes 10 Hunter, the master subaiituies him- Kvcry one will recognize llie auracliveiicss and Talue which this work derives from thus pre.«eniiDg the opinion" of these two masters side by side. Bui, It must I'O admitted, what has made the forlune oi the book, is ihe fuel lliai it coiiluius ilie "most coni- flele embodim^'iu of the veriublc doctrines of the lApital du Alidi," which has ever been made public. The doctrinal id<'as of M. Ricord. ideas which, if not universally adopted, aie incorilesiably dominant, have heretofore only been interpreted by more or lessskilful selfforhis interpreters, and gives hisoriginal ihoufrhts to ilie world in a lucid and perfectly iiilrlliijiblc man- ner. Ill conclusion we can say thai this is incon- lesiably the best treaiise on syphilis with which we are acquainted, and. as we do nol ofieii employ the phrase, wc may be excused lor expressing ilie hope thai it may find a place in the library of every phy- sician. — Virginia Mid. and Surg. Journal. BY THE SAME AUTHOR. RICORD'S LETTERS ON SYPHILIS. Translated by W. P. Lattimore, M. D. In one neat octavo volume, of 270 pages, extra cloth. $2 00. ROYLE'S MATERIA MEDICA AND THERAPEUTICS; including the Preparations of the Pharmacopoeias of London, Edinburgh, Dublin, and of the United btates. With many new medicines. Edited by Joseph Carson, M. D. With ninety-eight illustrations. In one large octavo volume, extra cloth, of about 700 pages. S.'^ 00. ROKITANSKY Curator of the Imperial Pathological Museum, A MANUAL OF PATHOLOGICAL bound in two. extra cloth, of nboiit 1200 pasres. KING, C. H. Moore, and G. E. Day. S-O .10 The profession is too well acquainted with the re- putation of Rokitansky's work to need our assur- ance that this is one of the most profound, thorough, and valualile books ever issued from the medical press. It IS .es lead lo new and important suggestions a,- to their practical use in disease. Within the scope thus designed by the auihor, no labor has been spared lo accumulate all the facts which have accrued from the experience of the profession in all airt^s and all countries ; and the vast amoimt of recent re^earches recorded in the periodical literature of both hemispheres has been zealously laid under contribution, resulting in a mass of practical iafonnatioii scarcely attempted hulierto in any similar work in the language. Our expectations of the value of this work were the practical utility of his book by passin;; briefly based on the well-known reputalion and cliaracter over the physical, botani 'al, aiid ennnnercial history of the author as a man of scholarly attainments, an nf medicines, and direciiiig attention ehitfly to their elegant writer, a candid inquirer after truth, and a physiological action, and their application for the philosophical thinker ; we knew that the task would amelioration or cure of disease. He igrnores hypothe- be conseieiitinusly performed, and that few, if any, sie and theory which are so alluring to many medical ainoD^ the distinguished medical teachers in this writers, and so liable to lead them astray, and con- counlry are Ijettcr qualified than he to prepare a fines himself to such facts as have been tried in the systeaatic treatise on therapeutics in aecnrdance crucible of experience. — Chicago Medical Journal, with the present requirements of medical science, i March, ISOO. Our priliminary examination of the work has satis- , The plan pursued by the author in these veryela- fied us that we were not mistaken in our anticipi- borate volumes is not strictly one of scientific unity li.ms. In cmjratulating the au-hor on the comple- (j^j precision ; he has rather subordinated these to tion of the great labor which such a work involves, | practical utility. Ur. Stille has produced a work we are happy in expressing the conviction that its , which will be valuable equally to the student of merits will receive that rew.ard which is above all medicine and the busy practitioner. -i-o/iioTi Lan- price— the grateful apprtciation of his medical bre- jjj Alarch 10 1S60. thren.— Ntw Orleans Medical News, M&TCh, ISOO. ,',r-.u ti •' n' i- i\t-. in Aitr ju ' ' I Wilh Pereira, Dunglison, Mitchell, and Wood be- We think this work will do much to obviate the j fore us, we may well ask if there was a necessity reluctance to a thorough investigation of this branch , for a new book on the subject. After examining this of scientific study, for in the wide range of medical ' work with some care, we can answer affirmatively, literature treasured in the English t(mgue, we shall [ Dr. Wood's book is well adapted for students, while hardly find a work written in a style more cle.ir and j J)r. StiUe's will be more sitisfacfory to the practi- simple, cuDVpying forcibly the facts taught, and yet \ tioner, who desires to study the action of medicines, t'ree from tursridiiy and redundancy. There isa fas- i The author needs no encomiums from us, ("or he is cination in its pages that will insure to it a wide | well known as a ripe scholar and a man of the most popularity and attentive perusal, and a degree of ^ extensive reading in his profession. This work bears usefulnets not often attained through the influence' evidence of this fact on every page. — Cincinnati of a single work. The author has much enhanced i Lancet, April, IsOO. SMITH (HENRY H.), M.D. MINOR SURGERY; or, Hints on the E very-day Duties of the Surgeon. With 247 illustrations. Third edition. 1 vol. royal 12ino., pp. 456. In leather, $2 2-5; cloth, $2 00. BY THE SAME AUTHOR, AND HORNER (WILLIAM E.), M.D., Late Professor of Anatomy in the University of Pennsylvania. AN ANATOMICAL ATLAS, illustrative of the Structure of the Human Body. In one volume, large imperial octavo, extra cloth, wilh about six hundred and fifty beautiful figures. $3 00. These figures are well selected, and present a complete and accurate representation of that won- derful fabric, the human body. The plan of this Atlas, which renders it so peculiarly convenient for the student, and its superb artistical execution, have been already pointed out. We must congratu- late the student upon the completion of thisAtlaS] as it is the most convenient work of the kind that has yet appeared ; and we must aiUI, the very beau- tif^ul manner in which it is " got up" is so creditable to the country as to be flattering to our national pride. — ArTurican Medical Journal. SHARPEY (WILLIAM), M. D., JONES QUAIN, M. D., AND RICHARD QUAIN, F. R. S., &.c. HUMAN ANATOMY. Revised, with Notes and Additions, by Joseph Letdt, M. D., Professor of Anatomy in the University of Pennsylvania. Complete in two large octavo volumes, leather, of about thirteen hundred pages. Beautifully illustrated with over five hundred engravings on wood. $6 00. SIMPSON (J. Y. , M. D., Professor of Midwifery, &e., in the University of Edinburgh, Sec. CLINICAL LECTURES ON THE DISEASES OF FEMALES. With numo- rous illustrations. This valuable series of practical Lectures is now appearing in the "Medical News and Library" for 1560, and can thus be had without cost by subscribers to the "American Journal OF THE Medical Sciences." See p. 2. 28 BLANCHARD & L.EA'S3 MBUIUALi SARGENT (F. W.), M. D. ON BAXDAGING AND OTHER OPERATIONS OF MINOR SURGERY. Second edition, enlarged. One handsome royal 12mo. vol., of nearly 400 pages, willi 182 wood- cuts. Extra cloth, SI 40; leather, SI 50. Sareent's Minor s^urgpry hue always been popular, I A work that has been so long and favorably' known and deservedly »o. It furnislies that knowledge of the | to tlie profession ^as Dr^ Sargcnt^s Minor tjurgery, must f " , _ -. .,_, ~ ,..™ ..„ «,.,.,.. , ,„.».,. art wli loe cliDieal lectures. Tlie art of bandaging, which I dom gets that attention in our schools tliat its im- is regularly UuRlit in Europe, is very frequently I portance deserves. Our larger works are also very overlooked by teachers in this country ; the student defective in tlieir teaching on these siiuill practical and junior pruclilioner, therefore, may often require points. This little book will supply the void which that knowledge which this little volume so tersely all must feel who have not studied its pages.— TTeil- and happily supplies —CAor/es«o« Med. Journ. and em Lanctt, xMarch, lb56. 'requently requisite performances of surgical needs no commendation from us. We would remark, lieh cannot be entirely understood by attend- j however, in this connection, that minor surgery sel- ioical lectu ularly taug Miked by ten inior pructil nowledge v happily suppi iiavMio, March, lb36. SMITH (W. TYLER), M. D., PhysiciJUi Accoucheur to St. Mary's Hospital, See. ON PARTURITION, AND THE PRINCIPLES AND PRACTICE OP OBSTETKICS. In one royal 12mo. volume, extra cloth, of 400 pages. $125. BY THE SAME AUTHOR. A PRACTICAL TREATISE ON THE PATHOLOGY AND TREATMENT OF LEUCOKKliCEA. With numerous illu!«traiions. In one very handsome octavo volume, extra cloth, of about 250 pages. SI 50. SOI.LV ON THK HU.MAN BRAIN; its Structure, | handsome octavo volume, extra cloth, of overC50 Physiology, and Diseases. From the Secr the prevention ano Cure of Disease. In one SKEY'S OPERATIVE SURGERY. In one very ' octavo volume, extra cloth, of 212 pages. 81 25. TODD (R. B.), M.D., F. R. S., &.c. CLINICAL LECTURES ON CERTAIN DISEASES OF THE URINARY ORGANS AND ON DROPSIES. In one octavo volume, 2S4 pages. $1 50. BY THE SAME AUTHOR. {Now Ready.) CLINICAL LECTURES ON CERTAIN ACUTE DISEASES. In one neat octavo volume, of 320 pages, extra cloth. SI 75. The subjects treated in this volume are — Rheu.matic Fever, Continued Fever, Erysipelas, Acute Internal Inflammation, Py>e.mia, Pneumonia, and the Therapeutical Action of Alco- hol. The importance of these matters in the daily practice of every physician, and the sound practical nature of Dr. Todd's writings, can hardly fail lo attract to this work the general attention that it merits. TANNER (T. HJ, M. D., Physician to the Hospital for \Vomen, &c, A MANUAL OF CLINICAL MEDICINE AND PHYSICAL DIAGNOSIS. To which is added The Code of Ethics of the American Medical Association. Second American Edition. In oae neat volume, small 12mo., extra cloth, S7j cents. TAYLOR (ALFRED S.), M. D., F. R. S., Lecturer on .Medical Jurisprudence and Chemistry in Guy's Hospital. MEDICAL JURISPRUDENCE. Fourth American Edition. With Notes and References to A merican Decisions, by Edward Hartshorne, M. D. In one large octavo volume, leather, of over seven hundred pages. S3 00. No work upon the subject can be put into the | It is not excess of praise to say that the volume hands of students either of law or medicine which before us is the very best treatise extant on Medical will engage them more closely or profitably; and none couM be oflcred to the busy practitioner ol either calling, for the purpose of casual or hasty reference, that would be more likely toalTord the aid desired. We tlicrcl'ore recommend it as the best and ■afest manual for daily \xw.— American Journal oj Medical Sciences. Jurisprudence. In saying this, we do not wish to be understood as detracting from the merits of the excellent works of Beck, 'Ryan, Traill, Guy, and others; but in interest and value we think it must be conceded that Taylor is superior to anything that has preceded it. — iV. IV. Medical and Surg. Journal. BY THK SAME AtJTHOR. (New Edition, ju^t issued.) ON POISONS, IN RELATION TO MEDICAL JURISPRUDENCE AND MEDICINE. Second American, from a second and revised London edition. In one large octavo volume, ol 755 pages, leather. $3 50. Since the first appearance of this work, the rapid advance of Chemistry has introduced into use many new substances which may become fatal through accident or design — while at the same time il has likewise designated new and more exact modes olcouiUeractinir or detecting those previou>ly treated of. Mr. Taylor's po>ition as the leading medical juri>t of England, has during this periud conferred on him extraordinary advantages in acquiring experience on these subjects, nearly all cases of moment being referred to him lor examination, as an exj^ert whose testimony iti generally accepted as (inal. The results of his labors, therefore, as gathered together in this volume, cureliilly weighed and sil'ted. and presented in the clear and intelligible style for which he IS noted, may be received as an acknowledged authority, and as a guide to be Ibllowed with implicit cuufideuce. AND SCIENTIFIC PUBLICATIONS. 29 TODD (ROBERT BENTLEY), M. D., F. R. S., Professor of Physiology in King's College, London ; and WILLIAM BOWMAN, F. R. S., Demonstrator of Anatomy in King's College, London. THE PHYSIOLOGICAL ANATOMY AND PHYSIOLOGY OF MAN. With about three hundred large and beautiful illustrations on wood. Complete in one large octavo volume, of 950 pages, leather. Price $4 50. ^^ Gentlemen who have received portions of this work, as published in the " Medical News AND Library," can now complete their copies, if immediate application be made. It will be fur- nished as follows, free by mail, in pa|ier covers, with cloth backs. Parts I., II., III. (pp. 25 to 502), $2 50. Part IV. (pp. 553 to end, with Title, Preface, Contents, &c.), $2 00. Or, Part IV., Section II. (pp. 725 to end, with Title, Preface, Contents, &c.), $1 25. A magnificent contribution to British medicine, and the American pliysician who shall fail to peruse it, will have failed to read one of the most instruc- tive books of the nineteenth century. — iV. O. Med and Surg. Journal, Sept. 1857. It is more concise than Carpenter's Principles, and more modern than tlie accessible edition of .MQller's Elements; its details are brief, but sufhciert; its descriptions vivid ; its illustrations exact and copi- ous ; and its language terse and perspicuous. — Charleston Med. Journal, July, 1857. We know of no work on the subject of physiology so well adapted to the wants of the medical student. Its completion has been thus loni^ delayed, that the authors might secure accuracy by personal observa- tion. — St. Louis Med. and Surg. Journal, Sept. '57. Our notice, though it conveys but a very feeble and imperfect idea of the magnitude and importance of the work now under consideration, already tran- scends our limits ; and, with the indulgence of our readers, and the hope that they will peruse the book for themselves, as we feel we can with confidence recommend it, we leave it in tlieir hands. — The Northteestern Med. and Surg. Journal. TOYNBEE (JOSEPH), F. R. S., Aural Surgeon to, and Lecturer on Surgery at, St. Mary's Hospital. A PRACTICAL TREATISE ON DISEASES OF THE EAR; their Diag- nosis. Pathology, and Treatment. Illustrated with one hundred engravings on wood. In one very handsome octavo volume, extra cloth, $3 00. {Now Ready.) Mr. Toyiil'ce's name is too widely known as the highest authority on all matters connected wilk Aural Surgery and Medicine, to require special attention to be called to anything which he may communicate to the profession on the subject. Twenty years' labor devoted to the present work has embodied in it the results of an amount of experience and observation which perhaps no otlier living practitioner has enjoyed. It therefore cannot fail to prove a complete and trui^tworthy guide on all matters connected with this obscure and little known class of diseases, which so frequently embarrass the general practitioner. The volume will be found thoroughly illustrated with a large number of original wood-engrav- ings, elucidating the pathology of the organs of hearing, instruments, operations, &c., and in every respect it is one of the handsomest specimens of mechanical execution issued from the American press. The following condensed synopsis of the contents will show the plan adopted by the author, and the completeness with which all departinents of the subject are brought under consideration. CHAPTER I. Introduction — Mode of Investigation — Dissection. I[. The External Ear — Ana- tomy — Pathology — .Malformations — Diseases. III. The External Meatus — Its Exploration. IV. The External Meatus — Foreign Bodies and Accumulations of Cerumen. V. The External Meatus — The Dermis and Its Diseases. VI. The External Meatus — Polypi. VII. The External Meatus — Tumors. VIH. The Membrana Tynipani — Structure and Functions. IX. The Mem- brana Tympani — Diseases. X. The Membrana Tympani — Diseases. XL The En>tachiaa Tube — Obstructions. XII. The Cavity of the Tympanum — Anatomy — Pathology — Diseases. XIII. The Cavity of the Tympanum— Di.>eases. XIV. The Mastoid Cells— Diseases. XV. The Diseases of the Nervous Apparatus of the Ear, producing what is commonly called " Nerv- ous Deafness." XVI. The Diseases of the Nervous Apparatus, continued. XVII. Malignant Disease of the Ear. XVIII. On the Deaf and Dumb. XIX. Ear-Trumpets and their uses. Appe.ndix. WILLIAMS (C. J. B.), M.D., F. R. S., Professor of Clinical Medicine in University College, London, tea. PRINCIPLES OF MEDICINE. An Eleineataiy View of the Causes, Nature, Treatment, Diagnoses, and Prognosis of Disease; with briet remarks on Hygienics, or the pre- servation of health. A new American, from the third and revised London edition. In one octavo volume, leather, of about 500 pages. S2 50. (Just Issued.) We find that the deeply-interesting matter and i expressed. It is a judgment of almost unqualified style of this book have so far fascinated us, that we have unconsciously hung upon its pages, not too long, indeed, for our own profit, but longer than re- viewers can be permitted to indulge. We leave the furtheranalysis to the student and practitioner. Our Judgment ot the work has already been sufficiently praise. — London Lancet. A text-book to which no other in our language is comparable. — Charleston Medical Journal. No w^ork has ever achieved or maintained a more deserved reputation. — Va. M(d. and Surg. Journal. WHAT TO OBSERVE AT THE BEDSIDE AND AFTER DEATH, IN MEDICAL CASES. Publishediindertheauthority of the London Society for Medical Observation. A new American, from the second and revised Londoi. edition. In one very handsome volume, royal 12mo., extra doth. $1 00. To the observer who prefers accuracy to blunders I One of the finest aids to a yonng practitioner we and precision to carelessness, this little book is in- have ever seen. — Peninsular Journal of Mtdieint. valuable. — iV. II. Journal of Medic m*. I 30 BLANCHARD b LEA'S MEDICAL New and much enlarged edition— (Just Issued.) WATSON (THOMAS), M. D., Sec, Lute I'liysician tn the Middlesex Hospital, iic. LECTURES ON THE PRINCIPLES AND PRACTICE OF PHYSIC. Delivered at King's Colleee, London. A new American, from the las-t revised and enlarged Enffli^'h edition, with Additions, by D. Francis Co.ndie, M. D., author of "A Praciical Treatise on the Di>eu*es olC'hildren," ice. With one hundred and eighty. five illustrations on wood. In one very large and handsome volume, imperial octavo, of over 1200 closely printed pages in email type; the whole strongly bound in leather, with raised bands. Price $4 Qf). That the high reputation of this work might be fully maintained, the author has subjected it to a ihorouKh revision; every portion has been examined wiih the aid of the most recent researches in pathology, and the results of modern investigations in both Iheore'.ical and practical subjects have f»een carefully weighed and embodied throughout its pages. The watchful scrutiny of the editor has likewise introduced whatever possesses immediate importance to the American physician in relation to diseases incident to our climate which are little known in England, as well as those points in which experience here has led lodilferent modesof practice ; and he has also added largely to the series of illu>trations, believing that in this manner valuable assistance may be conveyed to the student in elucidating the text. The work will, therefore, l)e found thoroughly on a level with the most advanced state of medical science on both sides of the Atlantic. The additions which the work has received are shown by the (act that notwithstanding an en- largement in the size of the pagp, more than two hundred additional pages have l>een necessary to accommodate the two large volumes of the London edition (which sells at ten dollars), within the compass of a single volume, and in its present form it contains the matter of at leaBtematic work on tlie Principles and Practice of of merit in others. Mny le lo'ug remain to instruct Physic in the whole range of medical literature, us, and to enjoy, in the glorious sunset of his de- Every lecture contains proof of the e.xlreme anxiety dining years, the honors, the confidence and love of the author to keep pace with 'he advancing know- gained during his useful life.— iV. A. Med-Chir. ledge of the day, and to bring the results of the Reviete, July, ISSti. labors, not only of physicians, but of chemists and ,,. , • ., j ,_ t u, histologists, before his readers, wherever they can Watson's unrivalled, perhaps unapproachable be turned to useful account. And this is done with work on Practice-the copious adduions made to such a cordial appreciation of the merit due to the which (the fourth edition) have given it all the no- industrious .)b8erver, such a generous desire to en- v^lty and much of the interest o| a new book.— courage younger and rising men, and such a candid Charleston Med. Journal, July, 165... acknowledgment of his own obligations to them. Lecturers, practitioners, and students of medicine that one scarcely knows whether to admire most the ^yjn equally hail the reappearance of the work of pure, simple, forcible English— the vast amount of Dr. Watson in the form of a new— a fourth— edition, useful practical intormatin in their fourth eiliiion,abfmnding in those third edition, which has been severely felt for the distinguished attributes of moderation, judgment, last three years. For Dr. Watson has not merely erudite cultivation, clearness, and eloquence, with caused the lectures to be reprinted, but scattered which they were from the first invested, but yet [ through the whole work we find additions or altera- richer than before in the results of more prolonged tions which prove that the author has in every way observation, and in the alile appreciation of the ] sought to bring up his teaching to the level of th« latest advances in pathology and medicine by one j most recent acquisitions in science. — Brit, and For. of the most profound medical thinkers of the day. — Medieo-Chir. Hevieui, Jan. 165S. London Lancet, Nov. 14, 1857. | WALSHE (W. H.), M. D., Professor of the Principles and Practice of Medicine in University College, London, ie. A PRACTICAL TUKATISE ON DI-JEASES OF THE LUNGS; including the Principles of Physical Diagnosis. A new American, from the third revised and much en- larged London edition. In one vol. octavo, of 4b8 pages. {Just Issued, June, 1860.) §2 25. The present edition hns been carefully revised and much enlarged, and may be said in the main to be rewritten. Descriptions of several diseases, previously omitted, are now iiitrixluced ; the causes and mode of produc-tion of the more important allcclions, so far as they possess direct prac- tical significance, are succinctly inquired into; an effort has been made to bring the description ol anatomical characters lo the level of the wants of the practical physician ; and the diagnosis and prognosis of each complaint are more completely considered. The sections on Treat.mext and the Appendix (conceriiiiig ilic intluence of climate on pulmonary disorders), have, especially, been largely extended. — Aiit/ior's Preface. 0,*^ To be followed by a similar volume on Diseases of the Heart and Aorta. WILSON (ERASMUS), F. R. S., Lecturer on Anatomy, London. THE DISSECTOR'S MANUAL; or, Practical and Surgical Anatomy. Third American, from the last revised and enlarged Engli^h edition. Modified and rearranged, by William Hunt, M. D., Demonstrator of Anatomy in the University ol Pennsylvania. In one large and handsome royal 12mo. volume, leather, of 582 pages, with 154 illustrations. $2 00. AND SCIENTIFIC PUBLICATIONS 31 Ne'w and much enlarged edition — (Just Issued.) WILSON (ERASMUS), F. R. S. A SYSTEM OF HUiMAN ANATOMY, General and Special. A new and re- vined American. frt)m the last and enlarged Eiigli>h Edition. Edited by W. II. Gobkkcht, M. D. Professor of" Anatomy in the Pennsylvania Medical College, &:c. lllnstrated witli liiree hundred and ninety-seven engravings on wood. In one large and exquisitely printed octavo volume, ol over 600 large pages; leather. $3 25. The publishers trust that the well earned reputation so long enjoyed by this work will l)e more than maintained by the present edition. Besides a very thorough revision by the author, it has been most carefully examined by the editor, and the elTorts of both have been directed to introducing everything which increased experience in its ii>e has suggested as desirable to render it a complete text-book tor those seeking to obtain or to renew an acquaintance with Human Anatomy. The amount of additions wliich it has thus received may be estimated from the (iict that the present edition contains over one-fourth more matter than the last, rendering a smaller type and anenlar^'ed page requisite to keep the volume within a convenient size. The author has not only thus added largely to the work, but he has also made alterations throughout, wherever there appeared the opportunity of improving the arrangement or style, so as to present every fact in its most appro- priate manner, and to render the whole as clear and intelligible as possible. The editor has exercised the utmost caution to obtain entire accuracy in the text, and has largely increased the number of illustrations, of which there are about one hundred and fifty more in this edition than in the last, thus bringing di>tinctly before theeye of the student everything of interest or imjiortance. It may be recoininencled to the student as no less , beauty of its mecliiinical execution, and the clear- distinguished by its accuracy and clearness of de- ness of tlie descriptions whidi it contains is equally scriptnm tli;in by its typograpliical elegance. The evident, l^et, students, by all means examuie the wood-cuts are exquisite. — Brit, and For. Medical claims of this work on their notice, bel'ure theypur- ""■""'""" chase a text-book of the vitally important science which this volume so fully and easily unfolds. Lancet. Review. An elegant edition of one of the most useful and accurate systems of anatomical science which has been issued from the press The illustrations are really beautil'ul. In its style the work is extremely concise and intelligible. No one can possibly take We regard it as the best system now extant for students. — Western Lancet. It therefore receives our highest commendation. up this Volume without being struck with the great ] Southern Med. and Surg. Journal. BY THE SAME AUTHOR. (Just Issued.) ON DISEASES OF TPIE SKIN. Fourth and enlarged American, from the last and improved London edition. In one large octavo volume, of 650 pages, extra cloth, $2 75. The writings of Wilson, upondiseases of the skin, l at some of the more salient points with which it are by fir the most scientific and practical that abounds, and which makeilincomparaurysupcriorin have ever been prcsent«'d to the medical world on excellence to all other treatisesoine octavo volume, oC nearly GOO pages. {Just Issued, June, IMJQ.) §3 GO. The momentous questions discussed in this volume have perhaps not hitherto been so ably and elaboralelv treated. Dr. Winslow's distinguished reputation and long experience in everything re- lating to insanity invent his teachings with the highest authority, and in. this carel"ully considered volume he has drawn upon the accumulated resources of a life ol" observation. His deductions are lounded on a vast number of cases, the peculiarities of which are relaied in detail, rendering tlie work not only one ol sound in^truction, but of lively interest; the author's main object l)eing to point out the connection between organic disease and insanity, tracing the laiter through all its blages Iroiu mere eccentricity to mania, and urging the necessity of early measures of prophylaxis and u|>iiropriute treatment. A subject of greater importance to society at large could scarcely be named ; while to the physician who may at any moment be culled upon for interference in the most delicate relations of life, or for an opinion in a court of justice, a work like the present may be con- sidered indisjieusable. The treatment of the subject may be gathered from the following summary of the contents : — Chapter I. Introduction. — II. Morbid Phenomena of Intelligence. III. Premonitory Symptoms of Insanity- — IV. Confessions of Patients after Recovery. — V. Stale of the Mind during Re- covery. — Vl. Anomalous and Masked Affections of tlie i\lind. — VII. The Stage o( Coii.-eiousness. — Vlll. Stage of Exaltation. — IX. Stage of Mental Depression. — X. Siage of Aberration. — XI. Impaifmcnt of Mind. — Xil. Morbid I'henomena of Attention. — XIII. Morbid Plienomena of Memory — XIV. Acute Disorders of Memory. — W. Chronic Affections of Memory. — XVI. I'erversion and lOxaltalion of Memory. — XVII. Psychology and Palholcgy of ileinory — XVIII. Morbid I'henomena of Motion. — XIX. ISIorbid Phenomena ol Speech. — XX. Morbid Phenomena of Sensation. — XXI. iMorbid Phenomena of the Special Senses. — XXII. Morbid Phenomena of Vision. Hearing, Taste, Touch, and Smell. — XXIII. Morbid Phenomena of Sleep and Dreaming. — XXIV. Morbid Phenomena of Organic and Nutritive Life. — XXV. General I'rinciples of Pa- thology, Diagnosis, Treatment, and Prophylaxis. WEST (CHARLES), M. D., Accoucheur to and Lecturer on Midwifery at :»t. Biirtlmlomcw's Hospital, Physician to the Hospital for Sick Chililreii,&c. LECTURES ON THE DISEASES OF WOMEN. Now complete iu one hand- some octavo volume, extra cloth, of about 500 pages; price $2 50. Also, for sale separate, Part II, being pp. 809 to end, with Index, Title matter, (See, Svo., cloth, price $1. and children is not to be found in any country. — Southern Merl. and Svrg. Journal, January ISSe*. We gladly recommend his Lectures as in the high- est degree instructive to all wtio are iuterestcd in obstetric practice. — London Lancet. We have to say of it, briefly and decidedly, that it is the best work on the sutjject in any language; and that it stamps Dr. West as the facile princeps of British obstetric authors. — EUinb. Med. Journ. We mustnnw conclude this hastily written sketch with the confident assurance to our readeis that the work will well repay perusal. The conscientious, painstaking, practical physician isapparent on every page. — A'. Y. Journal of Medicine, March, 1858. We know of no treatise of the kind so complete an'l yet so compact. — Chicago Med. Journal, Janu- ary, 185a. A fairer, more honest, more earnest, and more re- liable investigator of the many diseases of women BY THE SAME AUTHOR. {Nolo Ready.) LECTURES ON THE DISEASES OF INFaNCI AND CHILDHOOD. Third American, from the fourth enlarged and improved London edition. Iu one handsome octavo volume, extra cloth, of about six hundred and fifty pages. $3 75. The continued favor with which this work has been received has stimulated the author to ren- der it in every respect more complete and more worthy the confidence of the prol'ession. Con- taining nearly two hundred pages more than the last American edition, with several additional Lectures and a careful revision and enlargement of those formerly comprised in it, it can hardly fail to maintain its reputation as a cle»»r and judicious text-book for the student, and a safe and reliableguide for the practitioner. The fact staled by the author that these Lectures '• now embody the results of 'JOO observations and "288 post-mortem examinations made among nearly oO,000 children, who, during the past twenty-years, have come muier my care," is suliicient to show their high practical value as the result of an amount of' exjierience which few physicians enjcy. The three former editions of the work now before i diseases it omits to notice altogether. But those us have placed the author in llie foremost rank of who know anything of the present condition of lliosc physicians who have L'evotfd special attention pajdiatrics will readily admit that it would he next to the iliseanes of early life We aiteinpt no ana- to impossible to effect more, or elfeot it belter, than 1} lit of til is edit ion, l>ul may refer the reader to some i the accoucheur of St. Bartholomew's has done m a of the chapters to which the largest additiiins have I single volume. The lecture (XVl.) up(ui Disorcirs been made — those on Uiplitheria, Disonlcrs of the .Mind, niid lilincy, for instuiioe — as a prooi that the work IB really u new edition; not a mere roprint. In its prcienl shape it will be lound of the greatest possible service in the cvery-day prnetiee of nine- trnlliB of the professKm. — Med. times and Oazetle, L.'nd<.n,Dcc. in, l?ol>. All tilings considired, this book of Dr. West is of ihe Mind in children is an admirable specimen of the value ol the later inforinution eonvejed in the Lectures of Dr. Charles W'esl. — London Lancet, Oct. 2-2, 1S59. Since the appearance of the first edition, about eleven years ago, the experience of the author has doubled ; so that, whereas the lectures at first were founded on six hundred observations, and one hun- hy fur the best treatise in our language upon such dred and eighty dissections made among nearly four- niodihcations of morbid action and diseise as are teen thousand children, they now embody the results witnessed when we have to deal with infancy and I of nine hundred observations, and two hundred and childhood. It is true that it confines itself to such | eighty-eight post- mortem examinations made among disorders as come within the province of the phy- nearly thirty thousand children, who, during the iifian, and even with respect tn these it is unequal past twenty years, have been under his care. — ns regards minuteness of consideration, and some j British Med. Journal, Oct. 1, 1859. BY THE SAME AUTHOR. AN ENQUIRY INTO THE PATHOLOGICAL IMPORTANCE OF ULCER- ATION OF THE OS UTERI. In one neat octavo volume, extra cloth. $1 00. GENERAL LIBRARY UNIVERSITY OF CALIFORNIA— BERKELEY RETURN TO DESK FROM WHICH BORROWED This book is due on the last date stamped below, or on the date to which renewed. Renewed books are subject to immediate recall. -£5- m... r j i OCT ? i^^4 OCT 1 o 1954 JUn 2 19G4 Lih^-^'i^j/ 21-lOOm-l. '54 (1887816)476 :.:o) - v/ V A,\ '^ . .~i . '^■/i^^'.v