University of California • Berkeley « A.a«.^-.jyu^' '^'j:'^' ^ \ DISSERTATION ON THE INFLUENCE OF A CHANGE OF CLIMATE IN CURING DISEASES. DISSERTATION ON THE Influence of a Change of Climate in Curing Diseases^ BY PROFESSOR GREGORY, OF EDINBURGH. Translated from the original Latin, and enlarged with occasional Notes: BY WILLIAM P. C. BARTON, M. D. " Pessimum segro est coelura quod segrum fecit; adeo ut in id quoque genua^ quod natura pejus est, in hoc statu, salubris mutatio sit." C£Lsus ns Rs Mkdica. PHILADELPHIA: PUBLISHED BY THOMAS DOBSON, AT THE STONE HOUSE, NO. 41, SOUTH SECOND-STREST. WilUam Fry, Printer, 1815. District of Pennsylvania, to wit: ********* BE IT REMEMBERED, That on the second day of May, I Seal. * in the thirty-ninth year of the independence of the United *«««««««» Stites of America, A. D. 1815, Thomas Dobson, of the said district, hath deposited in this office tl»e title of a book, the right whereof he claims as proprietor, in the words following, to wit: ** A Dissertation on the Influence of a Change of Climate in Cur- ing Diseases; by Professor Gregory, of Edinburgh. Translated from the original Latin, and enlarged with occasional Notes: By William P. C. Barton, M. D. * Pessimum 3cgro est ccclum quod segrum fecit; adeo ut in id quo- que genus, quod natura pejus est, in hoc statu, salubris mutatio sit.' — Celsus de Re JMedica** In conformity to the act of the congress of the United States, inti- tuled, •• An act for the encouragement of learning, by securing the copies of maps, charts, and books, to the authors and proprietors of such copies, during the times therein mentioned.*' — And also to the act, entitled, *• An act supplementary to an act, entitled, ' An act for the encouragement of learning, by securing the copies of maps, charts, and books, to the authors iiud proprietors of such copies during the times therein mentioned,' and extending the benefits thereof to the arts of designing, engraving, and etching historical and other prints.'* D.CALDWELL, Clerk of the District of Pennsylvania. TO NATHANIEL CHAPMAN, M.D. PROFESSOR OF MATERIA MEDICA IN THE UNIVERSITY OF PENNSYLVANIA: WHOSE TALENTS AND URBANITY HAVE ELEVATED HIM TO THE HIGHEST EMINENCE IN HIS PROFESSION; IN GRATEFUL ACKNOWLEDGMENT OF MANY ACTS OF FRIENDLINESS, AND IN EVIDENCE OF ESTEEM, JS RESPECTFULLY DEDICATED BY HIS FRIEND, THE TRANSLATOR. CONTENTS. Page Section I.— -General observations relative to the effects of climate on the human constitution, and ^specially re- specting the effect of that of Great Britain on the inha- bitants. — Remarks on the constitution of the air, and its modus operandi on the solids and fluids of the body; also, of the disorders induced by its inclemency, and the sudden vicissitudes to which it is liable.— Of the effects of sailing on the system, and the peculiar kind of nausea, vomiting, and exercise, arising from it.— Observations tending to prove that a change of climate may reasonably be expected to cure many obstinate chronick diseases, and more especially those endemi- cal to the inhabitants of Great Britain IT Section II. — Of the nature and symptoms of pulmonary consumption, and its similarity or identity with scrofula. Of the different notions of physicians respecting the curableness and incurableness of genuine phthisis.— Of the effects of wounds and other injuries of the lungs, on that viscus.- — Of the remote and proximate causes of consumption, and the reasons that may be 8 Page deduced from them, in favour of a change of climate upon the diseases.— Of the curative effects of travel- ling, riding on horseback and sea-voyages 76 Section III.— .Of the causes of hypochondria, especially its origin from the effects of climate, diet, and mode of life. — Its various symptoms.— Its connection with the haemorrhoidal flux and its affinity to this disease, deduced from the similarity of its causes.-— The general absence of any praeternatural appearances in the dissection of the dead bodies of hypochondriacks.— Sometimes tur- gescence in the mesenterick veins observable.— The different remedies for this disease. — The beneficial effects of riding on horseback, especially when conjoin- ed with a change of climate 155 Section IV. — Of gout.— Of the effects of a cold and humid climate on arthritick constitutions, and the ge- neral incfficacy of the remedies used in this disease. — The advantage of a change of climate over all other remedies in this complaint, particularly from a cold to a warm one, deduced from the effects of travelling and warm air, in promoting a free and healthy determina- tion of the fluids to the skin, especially in old persons. — Also the beneficial effects of a mild climate on the disorders of the stomach, so intimately connected and almost always combined with gout. — Arguments in favour of a change ef climate in gout, inferred from a consideration of the remote causes of the disease Of ' 9 Page its effects in averting the ill consequences of repressed gout, which generally succeed the use of other reme- dies 176 Section V. — Of invigorating old age— The signs and effects of declining life in old persons, and the particu- lar consequences of the depreciated functions of the system .-^Reasons why a change of climate may be ex- pected to relieve them, and produce a general invigora- tion of the fading body.— Of the injurious effect of a cold and humid climate upon old people, and the ad- vantages to be derived from travelling to warm coun- tries . . 190 B PREFACE. The original of the following Dissertation, is from the classick pen of Dr. Gregory, professor of medi- cine at Edinburgh, and author of the Conspectus. It was written for his inaugural Thesis in the year 1774, under the title " De Morbis Coeli Mutatione Medendis," enlarged and amended by the author in 1776, and republished in 1785 in the " Thesau- rus Medicus Edinburgensis Novus." It is from this last edition that the translation is made. This dis- sertation, besides its classical Latinity, contains many useful observations and important facts on the sub- ject of which it treats. The reasoning of the author is sound, his arguments pertinent, and his conclu- sions correct. He has treated an interesting subject judiciously and with ability, and satisfactorily de- monstrates the powerful operation of climate on the physical and moral constitutions. The pathology of this work is not the least important part of it. The 12 arguments in favour of a change of climate, in the treatment of many of the diseases which afflict the human race, are all logically deduced from an at- tentive consideration of the causes and symptoms of the diseases in which the author deems it expe- dient to recommend it: and it is believed that the translation may be useful as a mean of giving in- formation, on a subject not particularly treated in any other medical work in the English language. All the notes added are by the translator, and they are intended to convey such observations illustra- tive of the text, as his practical experience, while a surgeon in the navy, enables him to offer. With regard to the mere diction of the English version, but one end has been aimed at, which is, to render into intelligible English, what was believed to be the true meaning of the author, and never deviating even from the actual phraseology of the original, excepting in those instances where an adherence to it would have been incompatible with the idiom of our own tongue. As no liberties have been taken with the original, but have been on the contrary sedulously avoided, the reader must not look for, and he certainly will not find, the embellishments of style. If the translator has succeeded in present- 13 ing the publick with a literal and faithful version of the original into clear and unvarnished English, he will have accomplished his design, and be satisfied. He has not relinquished his intention, announced some time since, of presenting the medical publick with an English translation of the Conspectus Mc- dicinae Theoreticae. An engagement with a book- seller, is all that is necessary to enable him to com- ply with his promise. THE TRANSLATOR. No. 222, Walnut-street, Philadelphia. TABLE OF ERRATA. Page 38, line 2 from the bottom of note, for vascillancy, read vaciUancy. Page 41, line 4 of note from the top, for necisse, read necesse. Page 63, line 7 from the top, for vascUlation, read vacUlatton, Page 113, line 10 of the note, for patient, vesA patients. Page 131, line 6 from the bottom, for vascUlating, read vacillating. Page 83, line 1 of the note, leave out the word General, between parenthesis. Page 171, line 4 from the bottom, for concommitants, read concomitants. Page 174, lines 5 and 7 from the top, for vicera, read viscera* 3*age 174, line 9 from the top, for Carribeans read Caribbean. A DISSERTATION, &c. DISSERTATION OK THE INFLUENCE OF A CHANGE OF CLIMATE. IN CURING DISEASES. SECTION I. General Observations relative to the effects of Climate on the Human Constitution, and especially respecting the ef- fect of that of Great Britain on the Inhabitants. — Remarks on the Constitution of the Air, and its modus operandi on the Solids and Fluids of the body; also, of the Disorders induced by its inclemency, and the sudden vicissitudes to which it is liable. — Of the effects of Sailing on the Sys- tem, and the peculiar kind of Nausea, Vomiting, and Ex- ercise, arising from it. — Observations tending to prove that a change of Climate may reasonably be expected to cure many obstinate Chronick Diseases, and more especi- ally those Endemical to the inhabitants of Great Britain. Many of the diseases which afflict the human race, are endcmial to certain countries; while in others they rarely, or perhaps never occur. The tempera- ture of the atmosphere certainly produces various affections of the human system, so that the most of those disorders may be easily attributed to the per- C • 18 hicious properties of the air, aided in their operatioa on the body, by the influeHce of climate. There is a surprising difference in the mental constitutions, as well as in the corporeal systems, of the inhabitants of different countries; and in addition to this circum- stance, each revolution of the seasons of the year is accompanied by a train of diseases peculiar to itself, which it ushers in on its approach. Climate, and the state of the air, manifesdy induce a predisposi- tion to many disorders, and copiously abound also, as is very evident, with the exciting causes of dis- ease. We well know that winter produces various chronick complaints, which resist every medicine that may be exhibited for their relief, during a continu- ance of that season; yet these very disorders are cured with the utmost facility on the approach of summer. It is a well ascertained fact too, that there is so great a variation in the state of the air in dif- ferent countries, nay, even in the same country dur- ing the different seasons of the year, that the effects it produces on the system, are entirely dissimilar. Hence it is evident, that many disorders originating from an intemperate climate, might be prevented and cured by a change of air. That this is incontroverti- bly true, we infer from the fact: that innumerable 1^ maladies, after having baffled all the powers of the medicines that had been employed for their cure, disappear spontaneously, or become mitigated, by changing the climate,^ or upon a revolution of the season; and we are confirmed in the verity of this proposition, by the opinions of the physicians of an- cient times, who accord with those of our own day, in believing that a change of climate will prove emi- nently beneficial in a variety of complaints, that ar« curable with difficulty by any other means. In this essay, we shall attempt to advance some opinions relative to certain disorders endemial to our climate, and respecting the feasibility of their cure by a change of air. We will, however, previously 1 Every naval surgeon must have had occasioA to observe, what it has repeatedly happened to me to see: that almost all patients on ship-board, labouring under obstinate chronick complaints, which could in no way be managed or subdued in port, are cured spontaneously after a voyage of a week or two; especially if the vessel should have sailed from a port open to turbulent winds and intemperate weather, to a milder climate: or to another place, screened from the piercing blasts that sweep away the unfortunate victims of breast complaints, from the sick-bays of our ships during the win- ler season. 20 offer some remarks respecting the manner in which the climate of this country, in particular, injures the constitution. Observations hav^ clearly ascertained that coun- tries which enjoy a moderate, mild, and equable cli- mate, are the most salubrious; and those that are hot, cold, or humid, the most pernicious to health, espe- cially if they should be subject to sudden vicissitudes of the weather. Celsus long since remarked, that countries equably warm, or uniformly cold: and such seasons of the year as are remarkable for a like uni- formity in heat or coldness, are the most favourable to health; whilst those on the other hand, characte- rized by excessive variableness, are highly injurious. The truth of this observation is evidenced in the island of Great Britain, where the air during the four or five summer months is moderate and generally bland, dry, and equable; hence during this period it is universally agreeable and salubrious; all the re- maining part of the year, however, it is cold, humid, and variable; and consequently productive of exces- sive unhealthiness.^ « The climate of Great Britain is a peculiar one, and the state of the air variable in the extreme. A momentary glance 21 Physiology teaches us, that a due motion and cir- culation of the fluids throughout the whole system, are necessary to ensure the health of every part. Whatever therefore has a tendency to impede this healthy action, will accordingly derange the system. at its geographical situation, will explain the cause of this versatility of the weather, as well as of the turbulence of the prevailing winds throughout the year: and the almost con- stant haziness of the atmosphere during the winter, autumn and spring months. Being an island pretty far north, and not any part of it being much more than sixty miles from the sea, the air is generally cold and moist, and though the sea air itself from its moisture, has no unhealthful effect on the constitution even of a valetudinarian, yet it has always been remarked that places lying immediately in the face of its in- fluence, are rendered unhealthy by it. Hence it would seem that the insalubrity of the air in the vicinity of the sea is de- rived from some adventitious quality which it somehow re- ceives in its passage over the land. We may form some idea of the degree of moisture the atmosphere of an island like Great Britain, surrounded by the sea, must be endued with, when it is computed that from the Mediterranean Sea only, 5280 millions of tons of vapour rise in a summer day; it is true the evaporating causes are not so powerful in the sea surrounding Great Britain; but yet the moisture must be considerable. In Great Britain the winds two-thirds of the year are in the southerly and westerly quarters. Dr. Now, cold air, especially if it be humid, has a power- ful effect in checking perspiration and in impeding Dr. Campbell, in Lancaster, (England,) in the course af seven years found the winds to be in this proportion: Westerly, 216 days in the year. Easterly, 1 49 The direction of the winds was observed at Dover for three years, and they were Westerly, 321 Easterly, 173 In the city of Edinburgh the winds were observed to blow as follows: Anno 1797. West 256 days — East 109 days. 1798. West 250 days— East 115 days. Vide Transactions Roy. Soc. Edin. There is some similarity between the climate of England and the United States during the spring and winter seasons. The sudden transitions of the weather from the extremes of heat to cold, and vice versa, are as remarkable here as in Great Britain: and from actual observation I have found that the effects of these vicissitudes on valetudinarians on ship- board, are singularly similar and fatal, in both countries. There is this difference however in the relative state of the 23 the circulation of the blood through the external parts of the body. For the external application of atmosphere, that in England it is always more humid, espe- cially during the winter time, a circumstance undoubtedly owing to the vicinity of the sea. And though in the interiour of our country, and in the Atlantic states, at the distance of eighty or an hundred miles from the ocean, the air is gene- rally dry; yet in the tracts of country lying immediately on the sea-board, it is marked by the same humidity as that of England. Whether the state of the atmosphere in the United States is actually purer than that of Great Britain, is, I think, problematical, although Dr. Williamson leans to the opinion that the air of America is more pure than that of the coun- tries of Europe. This he infers from the circumstance of our repeated and successive clear blue skies, which may be ob- served night after night in the United States, adorned by countless stars; and these he remarks are seldom equalled in those parts of Europe frequented by travellers. (See his Essay on the Climate of America, Sec, page 175.) From this similarity of climate we may naturally expect that the diseases of this country will also be allied, and accord- ingly we find consumption and affections of the breast, very common in the eastern states. Hence we may infer that in cases similar to those for which Dr. Gregory recommends a voyage to a milder climate, much advantage may be de- riyed from travelling, either hy land, or by sea, from the northern and middle states to those of Carolina and Georgia. 24 of cold constricts the vessels and pores of the skin, while excessive moisture relaxes the muscular fibres, weakens the contractile powers of the heart, and cer- tainly diminishes the action of the arteries. The blood, consequently, is not propelled to the external parts of the body with due force. Whether this how- ever be the cause of the diminution, or whether it arises from other sources, it is unquestionable, that the perspiration is very considerably diminished dur- ing the prevalence of cold or moisture. The most imminent danger, however, arises from the sudden changes of the weather, which occur so frequently, nay, we might almost say daily, in this island.^ It is by the effect of these transitions, that 3 Whether this inconstant state of the air has really a prejudicial influence on the corporeal strength and health, seems to be doubted by highly respectable authorities. We are told, by Dr. Rush, in his account of the climate of Penn- sylvania, that " its variable nature does not render it neces- sarily unhealthy." In substantiation of this opinion, he quotes Dr. Huxham, who has, he says, " taught us that the healthi- est seasons in Great Britain have often been accompanied by the most variable vreather. His words,'* continues Dr. Rush, " convey a reason for the fact." < When the constit«- 25 the circulation of the fluids is most disturbed; for when the external surface of the body becomes sud- denly chilled, and the extreme vessels consequently constricted, the blood flowing freely and 4irectly to tions of the year are frequently changing, so that by the con- frast a sort of equilibrium is kept up, and health with it; ^nd that, especially if persons are careful to guard themselves well against these sudden changes.' f Huxham'sObservations on the Air and Epidemic Diseases, Vol. I. p. 5.]'* Whatever be the physical operation of these vicissitudes on the body, on land, it is very certain that their eifects at sea on the sys- tem, are neither trifling nor salutary; for I have never failed to remark, during my practice in the navy, that sailors al- ways suffered more or less from the sudden transitions of the weather. I must not omit to mention, however, that these effects of the quick changes of the weather, were sel- dom so frequent among the officers, and other persons on board, however great their exposure might be, who took more precautions to guard against danger than the impro- vident sailor can ever be brought to do. One thing is certain, that the changes of the weather in a climate where heat and cold prevail alternately, to a great degree, during the differ- ent seasons of the year, have no little influence on the moral state of the system. " The eifects of a climate of this kind," says Dr. Falconer,* « have not, as far as I know, been re- * Remarks on the influence of Climate, &c. on the Disposition, Manners, &c. &c. of Mankind, 4to, p. 24. D ' 26 the superficial parts is checked, and impelled imme- diately from them, inwardly, producing a copious and violent regurgitation. In like manner, when the invisible (;utaneous pores are clogged up, the perspi- ration is checked; and this is undoubtedly the most indispensable of all the excretions. These are the causes that produce internal congestion of the blood, which is frequently followed by inflammations and hemorrhages; they likewise engender fevers, and a marked by any modern writers, but did not escape the ob- servation of Hippocrates; though the countries he seems to rank in this class are, indeed, such as undergo considerable varieties in temperature at the different seasons; many parts of Europe for instance; but are still what are at present es- teemed to be in a moderate climate, and by no means sub- ject to such vicissitudes as a great part of North America, and that vast continent between Asia and Europe, called Si- beria and Tartary. Hippocrates observes, (Hippocrates de aeribus, aquis, et locis, § 39. 53, 54, 55.) that in such a cli- mate, the shape and character of the people are much less uniform, than in either a hot or cold country. This appears very probable, as the climate partakes of the extremes of both. He also thinks, that ' variations of climate make men more active in the affairs of life, more brave and resolute in their conduct, and more austere and rugged, though more upright and just in their behaviour.' " 27 great many other diseases. It is not surprising, there- fore, that our climate should be productive of a va- riety of dangerous maladies, nor that persons of the strongest constitutions should be afflicted with se- rious disorders. Generally, however, with the assist- ance of nature, we can easily guard, in healthy and vigorous temperaments, against every danger accru- ing from the climate, so that no disease will ensue from its effects, and even should any disorder affect the system, it will be of short duration. In many cases of dangerous disease, nature her- self^ as every physician knows, spontaneously affords the best remedy; and she certainly prevents by her powers, the accession, — or banishes when they may have arisen — innumerable disorders that could scarce- ly be cured by any other means. This happens in the case under our consideration at this moment, for as soon as the impetus of blood to the external parts is checked by the operation of cold, the action of the heart and arteries is simultaneously increased, and the pulse augmented in frequency and force. In con- sequence of this increase in the contractions and di- latations of the heart, the constriction of the extreme vessels which impeded the natural motion of the 2» blood is soon overcome and entirely removed; hence the customary distribution of the fluids, and the wonted equilibrium of the circulation are perfectly restored. But if the constitution shall have previously become feeble and enervated, or predisposed to any disease, it will not be able to bear the same unsea- sonable transitions of climate without injury. The vires medicatr ices naturae ^ which, under more pro- pitious circumstances, guarded the system against danger, and restored it from disease to health, are inefficient here. And it is very probable, that some particular part of the body which may have been pre- viously weakened or disordered, and which, conse- quently, has become incapable of sustaining the shock, — will be rendered the subject of an incurable malady. Thus it is, that the human constitution, provided indeed it be vigorous and sound, accommodates it- self so surprisingly to all variations of climate, from the coldest to the temperate, and the more fervid; that for the most part it suffers no injury from their diverse temperatures.'* Cold and moist air, such as *• " Perhaps no climate or country is unhealthy, where men acquire from experience, or tradition, the arts of ac- 29 prevails in treat Britain, is the least favourable to perspiration, and an equable distribution of the fluids; but nature has so amply provided for that inconve- nience, that the natural circulation of the fluids, in so far as is essential to health, is sufiiciently promoted: consequently, those who are blest with sound and robust constitutions, suffer little or no detriment from this cause. Yet we see, notwithstanding, many instances, in which the healthiest temperament af- fords no barrier to the hurtful incursions of the cli- mate of this country. It is probable, that there are critical and dangerous periods in some constitutions, and without doubt there are idiosyncracies arising from peculiarities in the manner of living, as well as from the various conditions of men, and from other causes not accurately investigated, which render per- sons who are in other respects perfectly vigorous, liable to diseases incidental to climate. It should be remarked, however, that although the irregular and Unseasonable variations of the weather, do certainly commodating themseh^es to it. The history of all the nations of the world, whether savage, barbarous, or civilized, pre- vious to a mixture of their manners by an intercourse witK strangers, seems to favour tins opinion." — Rush on the Cli- mate of Pennsijlvania. 30 exert most powerful effects on the consiitution, and tend to produce many serious disorders; yet it hap- pens, not unfrequently, that evils are imputed to the influence of chmate, which in fact it has but little agency in generating; and which really derive their origin altogether from other sources. For in every clime, however variable and insalubrious it may be, we find inhabitants enjoying perfect health; and no portion of the terraqueous globe gives birth to any race of beings, that are liable to be annihila- ted by the destructive effects of the climate they in- habit. It has not ever been observed either, that other animals are injured by the influence of their native clime, however insalubrious and intemperate it may be, and even under circumstances of the greatest pos- sible exposure to the power of its severity. We surely cannot doubt then, that men may be able to endure the irreguiar transitions of climate without either in- jury or danger, provided they live temperately. Nor can we for a moment beUeve, as we should by ad- mitting a contrary position to be true: that the creator and preserver of the human race would subject man- kind to a condition so rigorous and unjust. Besides, those men who are accustomed to a rude, and labo- 31 l-ious life, who are but little regardful of the u'nsea- sonableness of the weather, to the vicissitudes of which they are continually exposing themselves, cer- tainly live in the enjoyment of health and vigour like other animals; nor was it till he discovered and brought to perfection, artificial means of defending the body generally, from the extremities of the sea- sons, that man was subdued by the severity of his native cHme. Those, therefore, who are unskilled in the means of avoiding or guarding against tlie extre- mities of weather, seldom suffer any inconvenience from it; and it is only in proportion as men become afraid of exposing themselves to the intemperance of the air, and sedulously endeavour to avoid it — that they are rendered very susceptible of its effects. There is certainly but one method, by which men are enabled to defend themselves against the rigour of an unhealthy climate; namely, by rendering their constitutions so vigorous and robust, that they are in a situation to encounter and endure, the danger and inconvenience they cannot shun. It is not sur- prising therefore, that those who are accustomed to polished life, and to indulgence in various luxuries, should be solicitous to elude the rigorous excesses of the weather. For if, from the causes we have men- 32 tioned, we find that men in other respects very ro- bust, and in the full enjoyment of perfect health, can scarcely endure this severity without annoyance; how much danger is not to be dreaded for those who have inherited from nature, less healthy consti- tutions — who, from living intemperately, or other- wise unhealthfully, have rendered their systems sub- ject to various disorders — who from ill health, or from whatever cause are broken down and exhausted in strength — or finally, for those advanced in years, or continually inclined to depression of spirits, and in whom all the natural powers of the mind and the body are wasting away by degrees! It is in cases then of this nature, that we should seek another climate blest with the cheering aspect of a clear and serene sky, assisted in its happy effect upon the feelings by the genial influence of soft breathing zephyrs. Where the prevalence of pleasant and more agreeable manners and livelier scenes are calculated to soothe the feelings, to promote cheer- fulness, and to revive the declining powers of na- ture.* But let us pass on to the consideration of other ^ Dr. Cheyne in his most excellent work, on health and long life, tells us with singular brevity and quaintness, that 33 arguments tending to prove the efficacy of a change of climate in many diseases. How limited is human knowledge! How rarely does it scrutinize the unerring and indispensable causes of things! Even on our art, the light of sci- ence has, as yet, but coruscated! For as yet the na- ture of many diseases, as well as their remote and proximate causes, are either totally unknown to us, or at least but imperfectly comprehended. When- ever, therefore, we observe a disease endemial to any country, which seldom occurs under another sun, it is highly probable that this disorder is caused by " if the aged would lengthen out their days, they should re- move to a warmer climate, by which they may live as long as a croiv!^* — London edition of 1725, page 206. We are told too, that " the citizens of Rome who had worn down jtheJr constitutions by intemperance, addedjmany years to their lives, by migrating to Naples, and enjoying there, in a warmer sun, the pure air of the Mediterranean. And Sir William Temple says the Portuguese obtain the same be- nefit by transporting themselves to the Brasils, after medi- cine and diet cease to impart vigour to their constitutions in their native country."— i?wsA*5 Obser, on Gout. Inquiries^ Vol. II. p. 319. E 34 the influence of climate, and we may reasonably ex- pect that the patient labouring under such complaint will be benefited by travelling into a country ex- empt from the same disorder. And from the want of other and more certain sources of reasoning, I have supposed that an argument in favour of my opinion, might be deduced from this principle, and though indeed it is an uncertain one, yet I cannot think it altogether contemptible. In many diseases indeed, the proximate causes of which we are acquainted with — the curative indica- tion consists in promoting the perspiration, and re- storing the due circulation of the blood to the ex- ternal surface of the body, so that an excessive determination to the internal parts may be prevent- ed; or, if it shall have already taken place, that it may be immediately removed. Now I do not know of any remedy by which all these objects can be more speedily, more safely, or more agreeably ac- complished, than by a change of climate; and this change must be effected by means of a journey into a country enjoying a moderate degree of warmth. A new climate is preferable as a remedy, to every thing else, because the patient can derive the benefit of it ^5 not only for a few hours together, but for many months, nay, should it be necessary — for many years; and it is well known to physicians that many of those diseases which are denominated chronick, are so obstinate and difficult of cure, that a great length of time is required to subdue and remove them, even when the best and most efficacious me- dicines are daily employed; nor are they unacquaint- ed with the fact, that many medicines which act with great power on the system, will not bear to be fre- quently repeated for any length of time. The con- tinual exhibition of such active medicines for a long while injures the constitution, and in fact induces new disorders. Some, by continued use, lose their pristine virtues, and then consequently they produce no beneficial effect on the system; others, though safe and efficacious, become by long repetition so extremely unpleasant and ungrateful to the sick, that rarely is a patient \Yilling to persist in their use suf- ficiently long to receive any benefit. But this remedy may be continued for a considerable time, not only without danger, but actually with the greatest ad- vantage! It neither injures tlie constitution — nor loses its virtues by repetition — nor does it become un- pleasant to the sick! It is on thq^ contrary, for various 36 reasons, truly grateful. Neither does it debilitate the system, but, for the most part, greatly strengthens it. And lastly, if a change of climate is not of itself suf- ficient to remove the disorder, we should seek the adventitious aid of all the other remedies which have been useful at home. For all things are to be found in a happier clime, and they are often rendered more efficacious under the genial influence of a foreign sun. But there are some maladies, whose proximate causes, if they be not altogether hidden from our view, are at least veiled in uncertainty: while their remote, predisposing and occasional causes are suffi- ciently obvious. And it is evident to the observation of medical men, that the remote predisposing and ex- citing causes of many diseases, ai:ise from the influ- ence of our climate. That is to say, in the colder coun- tries you will find a certain tendency to inflamma- tion in diseases, usually denominated phlogistic dia- thesis, prevailing almost universally among the in- habitants, especially during the winter and in the spring. But in warmer countries, as is the case also with us in the summer season, this inflammatory dis- position is not so common. Hence we may reasona- 37 bly expect, that this disposition, whatever it may be, will either be entirely obliterated by a change of cli- mate, or at least that it will be greatly mitigated. In cold countries too, especially in those where a cloudy, moist and gloomy atmosphere depresses the spirits, all the faculties of the mind, as well as the powers of the body, grow feeble and enervated.^ The system becomes weak, languid and inactive, while the spirits grow dull, dejected and apathetick, of course the disposition is inclined rather to melancholy than * This position in, I think, questionable; and that it is so may be inferred from an attentive consideration of the direct action of cold upon the body, and its indirect effect upon the mind and disposition. The indirect action of external or ai- mospherick cold on the mind and feelings, is produced through the influence of its immediate effects on the corpo- real system. These effects are palpable to the senses, and simultaneous with the application of this powerful agent to the external surface of the body. Cold evidently blunts the acuteness of feeling; and this it does by so wrinkling the skin, that the cutaneous pores are corrugated and contract- ed in diameter. It operates also upon the cutaneous glands, by closing-^or clogging up their orifices, so that the free ad- mission of the irritating matter which in this or some other way, causes sensation, is prevented. Hence the intensity of • utaneous feeling, is considerably diminished. The external 38 cheerfulness. Hence is produced, as I shall after- wards have occasion to show, a tendency in the action of cold on the skin diminishes the quantity of perspi- ration. It also aflPects its tenuity, rendering it thick and more viscid. These combined effects produce a powerful influence on the mind, rendering it less sensible of the external im- pressions on the body; and by thus blunting the power of feeling, it renders the general system more insensible. The physiological operation of cold on the mind, and conse- quently its effects upon the temper, the disposition, and the feelings, cannot appear ambiguous, when we advert to its evident effects on the body as just described. That the cha- racter would in some measure be affected by these causes, seems natural to suppose. Accordingly it has been deci- sively asserted, and I believe with no little truth, that the inhabitants of cold countries are not subject to those violent vicissitudes of temper and that versatility of disposition, which characterize those of hot climates, where the highly excited sensibility of the system, and the almost morbid ten- derness of feeling, render the people susceptible of every varying impression to which the constitution is physically exposed. Hence the disposition of the inhabitants of cold countries, is more faithful, immutable and brave, and the behaviour more consistent, than that of people dwelling under the enervating influence of a fervid sun, and ever liable to the vascillancy of a mutable and capricious cli- mate. Though these peculiarities in the constitutional tem- 39 system to be affected by certain diseases. Now it is universally known that the case is exceedingly dif- per of the inhabitants of cold countries, are generally as- cribed, exclusively to the positive and direct action of the frigid air: yet it must not be forgotten that there ate other causes indirectly generated by the coldness of the climate, and some that are wholly independent of any such influ- ence — ^that have no little agency in assisting and confirming the eff'ects of air upon the physical and moral constitutions: such for example are food, clothing and exercise; as well as religion, government and laws. But even allowing for the adventitious aid of all these causes, the dominion of the effects of climate over the form, stature, and health of the body, is active, evident, unequivocal. Some writers, however, have leapt beyond the possible effect of the causes which are derived from climate, in the overstrained hypotheses they have promulgated, and which they have predicated on the physical and moral influence of climate on the human subject. In these ingenious though sometimes crude, un- philosophick, and not unfrequently chimerical theories, which indeed ought only to be viewed as the effusions of vivid and fanciful minds, they have not hesitated to refer all the variations in human constitution, form, stature and com- plexion: as well as all the inflections of the variable, nay, even changing human character; together with all the grades in morals, from the turpitude of vice to the beauty of virtue — to the effect of climate alone! While this subject is before 40 fercnt in countries moderately warm, dry and clear; for the inhabitants, at least generally, possess great activity of body, and enjoy an equable flow of spi- "me, I cannot refrain from quoting a passage from the inge- nious and learned inaugural dissertation of my friend Dr. Gibson, now Professor of Surgery in the Baltimore Col- lege of Medicine. Its pertinency to the subject of the pre- ceding remarks, is, I trust, a sufficient excuse for the cita- tion: " Praeter diaetam et artificium, sunt et aliae causae quae ad figuram corporis humani mutandam aliquantulum conferre possunt: hue spectant imitatio, varia exercitationis genera, vestimenta, scientia, religio, animi pathemata, coelum, et quaedam alia. Non forsan alienum erit pauca de coeli effec- tibus monere, etsi meo quidem judicio, in mutationibus fi- gurae animantium inducendis multo minus valet, quam non- nullis persuasum est. Dicitur staturam admodum humilem Indorum Eskimotarum, et quarundam aliarum gentium sep- tentrionalium deberl frigori maxime intenso, cui perpetue objiciuntur in iis regionibus quas ibcolunt. Tschutski tamen in terrae plaga aeque frigida saltern, si non revera frigidiorc, degunt, nihilominus inter homines procerissimos jure re- censentur. Minutam Eskimotarum staturam e genere cibi potissimum pendere colligerem, oleo enim Phocae Vitulinae, et Phocaenae maxime aluntur.* Hippocrates cceli regionem * Ellis' Voyage, &c. 4t rits. It is not difficult to believe then, that travelling in such countries would greatly correct and improve the gloomy disposition of which we have just spoken, and perhaps banish it entirely. There is another ad- vantage that we certainly derive from a change of climate, and it is one of great importance, namely, guarding against the occasional causes of many dis- eases. It is generally known that many severe dis- orders generated in this island, originate in the sud- in figura mutanda non parum valuisse opinatur, sic enim pergit, * Quicunque autcm altam habitant regioncm, planam, ventis expositam et aquosam, eorum formse magnae ac invi- cem similes et erectse. Qui vero macra, aquis carentia, et nuda loca tenent, horum formas necisse est esse asperas et vegetas.'* " Vitruvius qiioque huic sententise addictus est, verba ejus citare liceat," ' Ex roscido sere sub septentrioni- bus nutriuntur gentes immanibus corporibus, candidis colo- ribus, directo capillo et rufo, oculis caesiis, sanguine multo, quoniam ab humoris plenitate, coeli refrigerationibus sunt conformati. Qui autem sunt proximi ad axem meri- dianum, subjectique solis cursui, brevioribus corporibus, colore fusco, crispo capillo, oculis nigris, cruribus invali- dis, sanguine exiguo, solis impetu perficiuntur/f — Bisser- tatio Physica de Forma Ossium Gentilitia^ auctore Gulielmo Gibson, p. 92. * De iEre, Aqua, et Locis. f Vitruvius de Architectura, torn. yi. 42 . . den changes of the weather; and the danger arising from this source is scarcely evitable any other way than by travelling into temperate countries, where the weather, even of the winter season, is not at all liable to such sudden transitions. It follows therefore, that all the remote causes of such diseases as arise from the effects of our climate, may be avoided or abated in their pernicious effects by a change of air; and we all know of how much importance it is in the cure, we might almost say, of every malady, that these causes should be quickly removed/ A disorder "f A striking instance of the efficacy of removing patients from the place where the disease is produced, is related by Mr. Volney. It goes far to prove, tlmt sometimes a very circumscribed space is within sphere of the action of the remote causes of a disease, and consequently that a removal of the patient to a little distance only, from this local influ- ence, may oftentimes have a very beneficial effect. I will cite the passage in his own words: " In Corsica, fevers of the same kind regularly annoy several military posts in the island every year, and among others the little harbour of San Fiorenzo, bordering on a pestilential marsh of forty-five acres. Toward the end of summer, and in the first six weeks of autumn, they assume a putrid and malignant character, in consequence of the intensity of the heat and the exhala- tion; and it is necessary to relieve the French garrisons 43 frequently meets with a speedy cure after the removal of its remote causes, without the administration of every fifteen or twenty days, either wholly or in part, other- wise the soldiers would sink under their serious and ulti- mately mortal effects. Our physicians, after trying many re- medies, remarked, that two posts alone in the whole island were absolutely exempt, and that no fever ever approached forts Vivario and Vitzavona on Bogognano. Chance, as fre- quently happens, rendered the salubrious and even curative quality of these two situations more striking. A Swiss officer from the Orisons fell dangerously ill of the fever at San Fiorenzo, and having requested to be removed to fort Vi- vario, the garrison of which belonged to his own regiment, he was restored to life and health in less than a fortnight. The physician having repeated the experiment on some French soldiers in the hospital, it succeeded so well, that it has become the established practice, to send thither all the desperate cases of fever, which appear to be past the power of medicine; and if is observed, that the fever has never held out there beyond the eleventh day."— Fo/net/ on the Climate and Soil of the U. States, p. 289. In addition to the above fact, 1 can state from my own knowledge, two circumstances no less illustrative of the po- sition advanced by Dr. Gregory in the text. They occurred on board of the late United States Frigate Essex, while I was surgeon of that vessel. We were anchored in Plymouth 44 any medicines whatever; for the powers of nature are alone sufficient to cure diseases, when every obstacle sound (England) from the 11th of January, 1811, till the 14th of February following, and although we arrived there after a cold and stormy passage of fourteen days from Port Louis roads, in France, we had but fourteen cases on the sick list.* Plymouth sound is exposed to the piercing cold and moist winds from the British channel, as well as the frigid blasts from the bleak shores of Cornwall and Devon- shire; the number of sick of consequence soon increased, and in fact in a few days the sick list, which was daily aug- mented, was crowded with many cases of pleurisy, violent inflammatory catarrhs, and numbers of bad colds, all of which I found it difficult to subdue. On the fifteenth of Feb- ruary, the ship was got under weigh and moored in Barn- pool, immediately under the elevated shores of Mount Edg- cumbe, which effectually sheltered the decks from the chan- nel winds, while the neighbouring mountains on the other side, screened them from the penetrating shore-blasts. A day or two after this, all the patients began to mend, and in a few more they were quite recovered. The other fact is not less interesting, and is as follows: We arrived in Cowes Roads, Isle of Wight, on the 12th of April, 181 1, from Cher- * Four of this number were consumptive patients received from a French hospital, of whose cases I shall afterwards have occasion to say something, two of Catarrh, one of Scrophula, one of Hydrops Articuli, two of Syphilis^ three of Chronick Rheumatism, and one of Contusion. 45 to the recovery of the patient is taken away. Some- times however, the injury which the system. has rc- bourg, in France, having only anchored after our passage from that place one night at St. Helens. At this time we had but eleven on the sick list, although a day or two after I learned that the British fleet at Spithead, no great distance from us, had been visited by an epidemick catarrh, or in- fluenza, which was rapidly extending itself.* The air was * The following was the state of the sick list after the day of oiu- arrival at Cowesj: — On the 13th of April there were sick, 14 14th, also. - 14 15th, - IS 16th, - 14 17th, - 14 18th, - - 16 19th, - 15 20th, - - 13 21st, IS 22d, . 13 23d, . 14 24th, - - - - 14 26th, . 10 27th, - . 9 28th, . 9 29th, - - _ - - 10 SOth, - 10 1st of May, - 11 2d, 3d, 4th, 5th, & 6th, same, 11 7th, - 70 8tli, - . 78 9th, some chronick cases dis- charged, [- - Vo 10th, .... . .77 nth. . 99— sailed fromCowes Roads. 46 ceived from these causes is so extensive, that even m the event of the patient being removed beyond moist, cold and hazy, and the wind very variable. In a few days this influenza appeared on board of the Essex, and the sick list increased till the eleventh of May when it was at its maximum, there being on it 99 cases of violent inflamma- tory catarrh. This complaint had been daily extending itself throughout the ship, and had we not left that anchorage I have no doubt but that in a few days, every creature on board would have been afl*ected with it. On the eleventh however we sailed from Cowes and anchored in the afternoon of that day in Yarmouth roads, Isle of Wight. I found all the patients better on the next morning, and discharged forty-four. We left Yarmouth that morning, aiTd saited out of the English Channel at mid-day on the thirteenth. From this time the list rapidly decreased, so that on the seventeenth following there were but fourteen sick. I must not omit to mention that the same plan of treatment was pursued throughout, so that the change of place, assisted perhaps by the motion of the vessel, and the sea-sickness, effected the 12th of May, 44 discharged, 55 — Yarmouth Roads. 13th, 6 more discharged, 49 remaining. 14th, 7 discharged, 42 remaining, 15th, 3 discharged, 39 remaining. 16th, 6 discharged, 33 remaining. 17th, 19 discharged, and 14 remaining. The sick Hst remained pretty nearly in this state, and on the first of June there remained on it hut twelve, and most of those were chronick cases, and contusions from accidents. 47 the sphere of their influence, it requires the judicious use of proper medicines for a long course of time, before the constitution can be restored to its former healthiness. Yet even in these instances, the same caution is necessary to be observed in the curative intention, namely, the removal of the remote causes; for the cure of no disease can ever be reasonably expected, while its causes continue to operate — since they daily renew and augment the mischief they first produced. Lastly, there are remedies which are nearly allied in their action upon the system, to the effects of a warm climate. For instance: the warm bath, mild di- aphoretics, especially diluents, warmer and more abundant clothing than common, particularly flannel jackets worn next to the skin, frictions, frequent and moderate exercise — all excite perspiration, and pro- mote an equable circulation of the fluids. Remedies of this kind, as well as moderate heat, such as pre- vails in this island during the summer season, are of great use in various disorders. And since a moderately warm climate is observed to produce similar effects, is it not very reasonable to advise a journey into coun- tries enjoying such a climate? Thus thtn from ana- 48 logy of the effects produced by the remedies we have mentioned, it may easily be inferred, that a change of climate promises, in many disorders, great advan- tages. Finally, from attentive consideration of those cir- cumstances which have an injurious effect upon any particular disorder, we may plainly deduce the infer- ence: that a change of climate will prove a useful re- medy. For example: cold air inspired into the lungs excites coughing by producing an oppression of the chest; now this very agent increases the disease. Gouty persons also suffer not a little inconvenience from the same cause (to wit, cold air.) Yet persons so affected have it not in their power to avoid such an inconve- nience without going abroad into other countries, since their continuance in this island subjects them to perpetual exposure to its noxious atmosphere. Ex- perience proves therefore, that in these and similar cases there is something in our climate prejudicial to the sick, and though it may not absolutely be the cause of the malady, yet we may reasonably con- clude that a change of air would be of advantage: since great inconvenience and hazard, scarcely evita- ble in any other manner, will be easily warded off. 49 For these reasons particularly, if I am not mista- ken, a change of air by means of a journey into coun- tries that have the advantage of a moderately warm, dry, mild, and uniform climate, will be of infinite service in m^ny diseases incidental to this island. It must be observed however, that whatever benefit the sick derive from such a journey, must not be at- tributed altogether to a change of air and climate, since they receive at the same time the advantage of gentle and long continued exercise, which itself acts as a remedy scarcely less efficacious, in many com- plaints at least, than a change of sun. When the situ- ation of our patients is such as to require a milder climate, they are often obliged to perform a long journey of many weeks; and all physicians know that such journies produce powerful and often salutary effects on the human system. In a dissertation on the effects of a change of climate, the virtues of exer- cise are not indeed particularly to come under con- sideration; yet I do not think it foreign to the pur- pose to say a few words on this subject. In fact it cannot be deemed irrelevant to our reasoning; for the effect of exercise should always be taken into consideration when we recommend a change of cli- mate. The effects of both indeed are synchronous, G 50 and they produce nearly the same consequences, at least in the generality of cases, on the constitution. Besides, both reason and experience satisfactorily prove, that moderate and continual exercise, such as arises from a long journeys—promotes perspiration and a determination of the fluids to the surface; and there is no doubt but that many sick persons derive great relief from the effect of this exercise alone. Further than this, I am much mistaken if the cures of many diseases which are commonly imputed to a change of air,^ are not to be attributed to the in- fluence of this exercise. » The common practice in this and other countries of ad- vising valetudinarians to repair to vs^atering places for the benefit of the chalybeate waters, is proved by experience to be a judicious one. Yet so great is the advantage frequently resulting from these visits, that it would be unreasonable to impute it solely to the effect of drinking the waters. To the journey itself undoubtedly, and the exercise and change of scene and air resulting from it, as well as to the invigorat- ing influence of pleasant company and the hilarity derived from new and sometimes facetious companions, is to be re- ferred, all the good effects of these trials. Dr. Rush remarks in his essay on pulmonary consumption, that " the sulphu- rous and saline air of Libya between Mount Vesuvius, and ihe Mediterranean Sea, and the effluvia of the pine forests 51 When it is judged expedient to make trial of a change of cHmate with a view to its effects as a reme- dy, a question arises whether the patient should travel by sea or by land? It clearly appears from the observa- tions of many physicians of ancient times as well as of modern days, that a voyage alone, avails in no incon- siderable degree, in many complaints. The celebrat- ed Gilchrist published a beautiful dissertation a few years since, on the medical use of sea voyages, in which he plainly proves the remediate effects of sail- ing, and indeed it appears from his work, that in many diseases it acts as a most efficacious remedy. He relates the histories of many invalids who evident- ly were snatched from the very jaws of the grave, as it were, by the salutary operation of this remedy. Many things which occur during a voyage combine without doubt, in producing such an effect; and I am of Libya, were supposed in ancient times to be powerful remedies in consumptive complaints; but it is probable the exercise used in travelling to those countries, contribu- ted chiefly to the cures which were ascribed to foreign mat- ters acting upon the lungs." — Medical Inquiries, Vol. II. Page 145. 52 not disposed to denys that the moisture and equal temperature of sea air, the saline vapours, and other 9 The temperature of sea-air is unquestionably more uni- form, and warmer than the atmosphere of land. It has also been proved to be purer. Dr. Ingenhousz in a short voyage, instituted a series of experiments with a view to ascertain this fact. These are related in the 70th vol. of the Philosophical Transactions. He is of opinion, that the air of the sea, is, caeteris paribus, purer than that of land. His observations however were not made in different latitudes. In an ingenious paper by Dr. Adam Seybert containing ob- servations on land and sea air, published in the Transactions of the American Philosophical Society (Vol. 4. p. 262, No. 32) we have the results of some experiments performed by the doctor in different latitudes, and during different hours of the day. I will give these results in the words of the au- thor: " My experiments at sea sufficiently prove that the at- mosphere is considerably purer there than it is on land. Though there are some trifling differences in the results of sevei'al experiments, I have no reason to believe that they were owing to the different situation in point of latitude or longitude in which they were performed. I can form no sys- tem respecting such variations. Winds, temperature, rain^ &;c. do not seem to have produced them. As they did not ob- serve any regularity in their occurrence, they may perhaps 53 advantages, may have a good effect. But it is my opi- nion that whatever benefit is derived from sailing is to be imputed especially to exercise itself. Gilchrist has happily shown that sailing produces a sufficient degree of exercise for health, especially if the vessel be small and the sea rough. He shows also that this be attributed to certain unperceived errors which are una- voidably attendant on such trials. " That the air at sea should appear nearly of the same pu- rity in different latitudes does by no means astonish me; for if land air has certain matters mixed with it they are fierhafis absorbed; and if my supposition be true, that the influence of the sun's rays on the water tends to increase its purity, the opinion I entertain is not surprising. For when once purified, there are perhaps none, or few causes to render the air noxious aftdr it is wafted from our towns and cities over a large body of water. " It occurred to me that probably the purity of the air at sea varied at different periods of the day; to satisfy myself on this point I made several trials on the 10th and 17th of June last. On the 10th I performed them at 9 o.clock A. M. at 12, and at 6 o'clock P. M. On the 17th at 9 A. M. and at 12 o'clock. The result of all the experiments of the same day was exactly similar, at least not perceptibly different." 54 exercise possesses certain advantages peci\liar to it- self, and in particular cases, far excels all other kinds. ^'^ w I am sure it will not be uninteresting to give at length, the observations of Dr. Gilchrist on the peculiar kind of ex- ercise produced by sailing. They are so pertinent and true, that I need offer no apology for the quotation. " Sailing seems to correspond with most other exercises in their manner of acting, or their effects, and indeed to .comprehend them all. When it is not vehement it resembles walking, in the gentle continued action of the muscles with which that exercise is accompanied, when used in a mode- rate degree. The benefit derived from riding depends upon the continued succussion which the body suffers, and on be- ing carried with considerable quickness through the air. Now, in sailing, there is a greater succussion from the vo- miting; and in a ship driven by winds, a person is carried through the air with greater quickness tham in any other ordinary exercise. Again, at sea a various action of tiie mus- cles is produced by the motion of the ship, and the constant efforts that must be used to prevent falling; by which the body is put into all that variety of constrained, ever-chang'- ing attitudes observed in bowling, skating, rowing, and the like exercises, and in common labour. Exercise in a swing, or a coach, which sometimes causes vomiting, comes nearest to sailing, as does likewise our first exercise, the cradle. " Sailing 55 Another remedy indeed besides exercise is obtained by sailing, namely, that denominated sea- sickness", " Sailing then is an exeixise compounded of gestation, and that of a particular kind; a preternatural spasmodic motion in vomiting; and a singular action of the air: nor can any- other exercise lay claim to so many and such peculiar ad- vantages. « It is constant: for as the ship is in perpetual motion, day and night, sleeping and waking, one or other of these causes always takes place, contrary to all other exercises, in which the sick are usually employed but a short while together, and the intervals between the times of exercise are long. « Though sailing, considered in all its complex circum- stances, and powerful effects, is reckoned among the highest exercises, so as in some to cause great perturbation, it is really, after being a little used to it, the most gentle, and excites no irregular motion, or undue impetus of the fluids, with subsequent waste of them. Therefore it is not attended with lassitude, or lowness of spirits, with hurry and confu- sion, as other exercises often are. A man may sit or stand, walk, lean, or lie, as he likes best, and so relieve his body by a frequent change of posture, and prevent weariness. Other exercises of efficacy cannot be undertaken by those [For Note 11, see next Page,] 56 which frequently excites nausea and vomiting. This produces powerful, and in some diseases most benc- \ who are weak and wasted, under fever and inflammation, or in a colliquative state, and many other such cases; and lower exercises are insufficient for any great purpose of cure. But sailing is of mighty energy, yet safe; and, excepting the sea- sickness at first, is easily sustained. Scarce any circumstance of a disease in which it is proper, can forbid its use, while the frame of the body or mind is not too much broken, nor any part corrupted: nay, even in this last case it is often highly proper. " To all these, as farther advantages, we may add, that at sea, you constantly breathe a peculiarly salutary air; and that the action of the air is greater, and increased by your being often carried through it with uncommon velocity. There is likewise a greater action of the muscles, of all the muscles of the body, of muscles not exercised in any other ordinary exercise, or not exercised in the same man- ner, nor so forcibly, nor with such effects and continu- ance. Nor is there occasion, in undertaking a voyage, for so many precautions as are necessary to be observed in other exercises."— -Gi/cAns? on the Use of Sea Voyages in Medi- cine^ p. 17. 1* The prominent features of the nausea maritima are Striking and deserving of much consideration. When a per- 57 ficial effects. It was known a long time ago to physir cians, that nausea and vomiting were eminently us^- son goes to sea for the first time, he is commonly affected immediately upon his coming into blue water, as sailors term it, with slight giddiness of the head and a sense of tightness across the forehead; considerable and distressing nausea; a sense of motion in the stomach, and soon after violent, copious and convulsive vomiting. These effects generally continue for a few days, during which time they are most aggravated by an upright position of the body below decks, and less severe while inhaling the free air on deck, and in an horizontal position of the body when below. The nau- sea is always painfully increased by the odour of cooked meats, and especially by the disagreeable and peculiar smell of the bilge water pumped up at a regular hour, every evening. The odour from this putrid water is so nauseous and subtle, that it insinuates itself into all parts of the vessel, and while its power on the surrounding air is at its height it equally affects with disagreeable feelings, the veteran seaman and the tyro in sailing, producing on the latter however, infalli- bly, the most violent and convulsive puking. The motion of a vessel through the water is vehement, rapid, sometimes irregular, and in turbulent weather much interrupted by sudden lurches. That a violent commotion is communicated to the system by these combined motions, must seem evident to every one, but the peculiar effects and operation of it upon the mind ajid body of the person who may be the subject of H 58 ful in exciting perspiration, and in promoting and restoring the due circulation of the fluids to the ex- it, can only be thoroughly known by those who have expe- rienced it in their own persons. It must seem clear however, to every reflecting mind, that as this motion of the vessel is constant, though in a greater or less degree, a person at sea must be sensible of some permanent effect on the system, liable to augmentation and diminution in propor- tion as the weather is calm or turbulent. This accordingly is the case, and there are few persons who are not affected by costiveness, not only immediately after going to sea, but in some degree subject to it all the time they continue there. This effect I believe to be in no way dependant on, or in con- sequence of the peculiar aliment that is generally eaten at sea, but owing solely to the continual impulse communicated to the stomach and intestines by the rolling, tossing about and pitching of the vessel. I infer this from the fact that this cos- tiveness exists in a greater degree, in persons sailing in small vessels, of which the motion is short, quick, and pitching, than in larger vessels, as in frigates, where it is long and less often repeated in a given time Now though the more vio- lent affection of the stomach for the most part goes off after four or five days, or at farthest in a week or ten days, there is nevertheless a certain kind of affection of that organ, and which indeed is in a degree communicated to the system generally, that comes on during every heavy blow: namely a sensation when the ship lurches or pitches forwards as if one 59 ternal parts. They act powerfully also in promoting expectoration, when the lungs are oppressed with was falling, and upon the rising of the vessel upon the waves again, as if one was raised with it. This sensation, which is felt in the greatest degree when there is a cross or head sea, or when the ship, going before the wind, lurches from side to side, communicates to the abdominal muscles a con- vulsive and sudden action, so that the whole contents of the abdomen are compressed and expanded alternately with the rising and falling of the ship. This compression consequently operates on the diaphragm, forcing that muscle upwards in the same violent and convulsive manner, so that the visdera of the thorax are also sensibly compressed and expanded with the lurching and righting of the vessel. These ef- fects as I have before remarked are produced with every new turbulence of the sea, and as they are totally indepen- dent of the nausea and sickness before mentioned, may be considered as the more permanent effects of sailing. One other effect of the vessel's motion, is the constant and novel action of the muscles of the body, principally those of the lower extremities, to preserve an equipoise and to prevent falling. The centre of gravity constantly altering as res- pects locality, a continual and corresponding action of the muscles to preserve an equilibrium, is of course necessary; and this continual action of the muscles, novel, sudden and cnergetick, is the most permanent of the effects of sail-* ing. It is the exercise arising from this action of the mus- phlegm* A vomiting of this kind however cannot be long employed unless produced by sailing; in this cles, that brings such invigoration to the debilitated patient; fifid this action never ceases to be necessary during the slightest motion of the sea, except in a horizontal position of the body, and even then, in blowing weather one is frequently awakened from sleep by an involuntary exertion to avoid being thrown from the berth. I have uniformly observed that those persons who were slightly affected, or affected not at all, with vomiting, or nausea, suffered excessively from an affection of the mind and frequently from acute pain in the head, which was always considerably aggravated by the vio- lent pitching of the ship* Such are the effects of sailing upon the system as I have observed them, both in small vessels as packets, sloops of war, and in larger ones as frigates. I have never witnessed but three very distressing cases of sea-sickness, one a landman on board of the frigate United- States, in whom great emaciation, loss of appetite, and a ha- bitual convulsive retching: which continued after the ship came to anchor: and the other two, which were on board of the Essex, are particularly mentioned in my " Treatise on Marine Hospitals, &c." p. 153. The exercise of sailing is not only performed in a fine healthy and pure air, but it is constant in itself. The veteran seaman has the same continual action of nearly all the mus- cles of the body, perpetually exerting its salutary effects on the system, as the young sailor is subject to. But the mind manner it is not uncommonly excited for many days in succession, or during entire weeks; and experience loses in the first instance, by the influence of habit, its con- sciousness of this continued exertion of the muscles. In the latter case the exercise and consequences of sailing, are so novel and positive, that the mind dwells on them with more attention, until time and habit produce also on the new sailor, the same unconsciousness of the perpetual exertions of the body to preserve its proper position and to prevent falling prostrate with every pitch of the vessel. The same uncon- sciousness of the operations of the mind and the synchronous action of the muscles of the body, takes place in many of our common actions, which from long practice are so adroitly performed that we frequently are inclined to believe them, and they ordinarily appear to others to be involuntary; Thus for example the successive rapid and almost imper- ceptible movements of the fingers, and the synchronous actions of the muscles of the tongue, mouth and lips, in playing on the German flute, seem after long practice, to be independent of any act of the mind, since we are inclined to think it cannot produce such vehement and rapid operations. Yet here, each movement of the fingers and every action of the muscles before mentioned, are the effect of a distinct and vivid act of volition. This continual exercise of the muscles then when a ship is under sail, and which I have, before remarked is in some 62 proves that no danger or injury arises from it. Yet can I hardly believe, that a similar sickness produced by the operation of artificial emcticks, could be ex- cited for any time, without danger. At least few phy- sicians woiild recommend the experiment, nor would any patients follow such advice, but on the contrary would shrink with fear from so disagreeable a reme- dy. After the sickness has gone off, persons at sea enjoy excellent health, and have a keen appetite, not- withstanding they are almost without any other ex- ercise than what is derived from the motion of the ship itself. This motion as Gilchrist has properly re- marked, although a kind of gestation, performs the measure performed even during sleep, is one of the most salutary effects of sailing. By means then of this gentle and regular exercise, the circulation of the blood is vigorously promoted through every part of the body, producing so healthy an action in the minute vessels of the surface, that a uniform and copious perspiration is effected. This is carried off as fast as it is exhaled from the surface of the body, by the change of atmosphere and the perpetual succession of its stimulating effects on the skin. Hence it is that ther.e is always so intense and impatient an appetite felt at sea; for the food taken into the system after undergoing the cus- tomary alterations, speedily passes off, that is, the liquid portion of it, by perspiration. 63 office of exercise, and promotes the healthy circula- tion of the fluids. Besides this, another and natural exercise is accomplished by sailing. For according as the ship rises on the waves and is tossed about, a synchronous motion of the body is required, so that its position and equipoise may be subservient to the vascillation of the vessel; otherwise no person would be able to move, or scarcely to- stand or sit. In order to perform this motion, a moderate, frequent, and scarcely sensible exercise of almost all the muscles of the body is required; and this exercise is perform- ed without any intermission; so that, whenever any one takes a voyage he has the benefit of exercise, or at least of gestation, all the time he lies down in bed, or sleeps. Whatever good therefore is derived from regular moderate and continual exercise, in any dis- ease, is reasonably to be expected from sailing in preference to all other exercises. I am by no means ignorant that this remedy has been ineffectually tried in many cases; but I know that the most advantage- ous effects have been reaped from it, in others. And if any one will reflect upon the nature of those cases in which it has generally been employed, he will not be at all surprised that it has not always succeeded as might have been wished. For a trial of it is 64 rarely ever resorted to except in very dangerous, and not uncommonly altogether incurable diseases, as pulmonary consumption for example: indeed it often happens that the patients do not undertake the voy- age, until they are in the last stage of the disease, and all medical men know that when this complaint has continued for any length of time, the lungs arc so affected as to be almost incurable. ^^ " It appears that Dr. Gregory attributes to the effects of exercise alone, all the good derived from sea-voyages, while Dr. Thomas Reid on the contrary attributes their beneficial effects in pulmonary consumption, solely to the action cre- ated in the stomach, by the rolling and tossing of the vessel. Indeed ih this opinion he is confirmed by the histories related by Gilchrist, who has proved that many persons la- bouring under a pulmonary affection were cured by short voyages, some of a few hours only, where of course the ex- ercise, however advantageous it may in general be, was not sufficiently long continued to have had any share in these surprising cures. In this place it may not be amiss to men- tion that a French writer speaking of the effects of sea-voy- ages and the vomitings they produce, in pulmonary con- sumption, advances a theory relative to the cause of these vomitings, different from the generally received opinion. His words are as follow: " Je crois que le mal de mer, qui consist^e dans des vomissemens qui se continuent pendant 65 We all know that other kinds of exercise, as for instance, riding on horse-back, or gestation in a car- riage, upon which many medical writers, and parti- cularly Sydenham, bestow such commendations, al- though they have sometimes been very successful, are, nevertheless, often tried in vain. Sailing however possesses a great advantage over all other exercises: that is, that it can frequently be used when every other kind is prohibited on account of the debility of the patient. For this is so gentle and mild, that for the most part the invalid himself is scarcely sensible of it; and the sick can bear it without danger, how- ever feeble they may be. Indeed there are some in- stances of valetudinarians, already broken down by disease, and so weak, that they were not able to move themselves, who, after being carried on board ship, and having performed a voyage, have recovered plusieurs jours, et qui meme, chez quelques individus, sc font sentir pendant tout le trajet, depend autant de cette exaltation des forces internes qui s'irritent de la presence des fluides qui devaient appartenir d la transpiration cuta- nee, que de la march.e vacillante et du roulis du vaisseau.*' Traits sur la Xature et le Traitment de la Phthisic Piilmo- naire, par Julien Bonnafox-Demalet^ M. D. p. 169. 66 both their health and strength." In those cases there- fore, where the patients can neither bear riding on horseback nor gestation in a carriage, and when conse- quently they are incapable of performing joiirnies by land, a voyage certainly ought to be tried. But when the sick are able to travel by land to countries suita- ble to their condition, it is a matter of doubt whether a voyage should be preferred for this purpose. If it should be long, many inconveniences will arise from it, particularly on account of the food, for some in- valids require a diet consisting of milk" and fruit, 13 For a history of many interesting cases of this nature I beg leave to refer the reader who may desire further infor- mation on this subject, to the inestimable work of Gilchrist. 1* With regard to the necessity of milk as an essential constituent of the diet of any invalids whom it may be deem- ed proper to send to sea for their health, it may not be amiss to remark that as this article was chiefly prescribed in pul- monary consumption by physicians some time back, and as it is now esteemed rather a pernicious than an useful diet in this disease, no solid objection can arise from the want of it on ship-board, to the expediency of taking a voyage. Whe- ther the milk of the ass possesses any real virtues not com- mon to the milk of the cow and other animals, seems, in the opinion of physicians of this day, notwithstanding the ex- 67 which can scarcely be had during the whole of a long voyage; besides which the privations arising from it affect with dread and disgust, the feelings of men accustomed to the refinements and luxuries of polished life.** I would hardly venture to assert travagant commendations of it by the practitioners who preceded them by a few years, to be very problematical. But it appears to be agreed on all sides, that any kind of milk, taken by a consumptive patient in sufficient quantity to produce any positive effect, will for the most part do harm. Professor Barton in his lectures on the Practice of Physick, speaks of this article in strong terms of disappro- bation, so far as regards its employment as a diet in phthisis; and says he has known many instances of its producing a distressing fulness and oppression of the chest. " I confess this objection to sea voyages arising from the privations that must be endured, strike my mind with peculiar force. Objections predicated upon such grounds are formidable indeed. No human being can be susceptible of stronger emotions of disgust and wearisomeness of life, than I have felt at sea, from the necessity of encountering the privations of retirement, of peace, of social felicity, for months at a time together. Such was the gloom and des- pondency with which I was constantly affected during the prevalence of bad weather, that I was always firmly con- vinced if ever I should have fallen ill at sea, that the debili- 68 that the other advantages derived from sailing can compensate for this inconvenience; nor will I deny tating effect of a dejected mind, would inevitably have pre- vented my recovery. Knowing then that such feelings have existed in others, and having experienced them in myself, I think we should do well to deliberate seriously and long, on the temper and disposition of our patients, before we venture to prescribe a sea voyage for their relief. There are unaccountable repugnancies to the turbulent vexations of a sea life, as well as lively disgusts at the inevitable want of cleanliness that depends on it, which many men feel acutely. Would it not be a precarious practice to send such to sea? And if the stronger sex be frequently the victims of such deep-rooted and unconquerablea versions, how much more frequently must we not expect to find the fragile and delicate female, accustomed in her indisposition to the so- lacing comforts derived from the society of her friends, perhaps her children: as well as to the kind solicitude of an attentive nurse — loathing with painful disgust the very idea of existence, while the distressing sea-sickness de- prives her of energy, of spirits, and of the attention of her attendants whom a similar sickness perhaps renders nearly as much in want of assistance as herself? Nor can I subscribe to the beneficial eifect attributed by some to the transitions of the feelings from hope to fear and vice versa, so justly said to be common at sea. Dr. Gilchrist in his work on sea-voyages, (p. 67.) says, " living at sea must 69 that a journey on land, performed in a carriage, produces highly beneficial effects, resembling those be considered as having a mighty influence on the miQcl, which, by consent, will powerfully affect the body. In sailing there is a strange mixture of passions; and these are some- times in extremes. Sea-faring people are frequently agita- ted between hope and fear; are sometimes merry, sometimes sad; exulting with joy when safe, and at rest; and in danger thrown into the utmost despair. Such variations and budden transitions of passions, are capable of removing the most in- veterate diseases, and such as are not curable by any other method.*'* I will venture to assert that the learned author whom I have just quoted, never practised mddicine exten- sively on ship-board at sea. I have never failed to observe the prejudicial nay, I may say in some instances, the fatal effects on my patients at sea of the violent and sudden ebul- litions of hope succeeded by dejection and despair, so fre- quently produced from the interest almost all persons take in the safety and comfort of the ship and the state of the weather. I have known a paroxysm of an intermittent acce- lerated by a " head-wind" being announced to the unfortu- nate subject of the disease, whose-hopes of happiness, of * Venim gestatio per pelagus vehementissiroa est, et mutationes plurimas, et maximas facit Nimirum cum anima mLxtos affectus habeat, ex tristitia et spe, tiinore et j)ericuIo; modo gaudentibus et latis, modo in agone existentibus na- vigantibus. Omnia hsec composita sufficientem vim habent omaem veterena xnorbum exigei di, et e eorpore exoludendi." — *Mtiu8 Medicin, contract, tetrab. prim. serm. 3. cap. 6. 70 too, that arise from sailing. Those therefore who are in affluent circumstances, and who retain strength health, of joy, depended on the speedy arrival of the vessel " at the haven v^here she would be.** Can the debilitating effect of depressing emotions be less active at sea than on land, under similar circumstances? Or is the excitability of the system less alive to impressions there? Surely not. Since then these vicissitudes in feeling are found to be so preju- dicial to the morbid constitution on land, we may natu- rally conclude that they exert no less unwholesome effects on the debile system at sea. I have been much at sea, and am a strong advocate for the use of sea-voyages in medi- cine. I kno'Uf their efficacy, for I h^ve been an eye-witness to their power in relieving those who were beyond the reach of medicine. I have seen the last scintillating light of life, fanned into a bright and burning flame, by means of this mighty influence; but I would yet discourage the too hasty recourse to this remedy. I know it has done good, I believe it may do harm. In speaking as I have done respecting the dejection of mind that a sea-voyage sometimes produces, I am not ignorant that highly respectable, nay celebrated au- thors have maintained a contrary opinion. With deference I have ventured to oppose the powerful current that flows against me; and I can only say that what I have advanced is grounded upon a strict and unwearied attention to the ef- fects of the sea life upon all those with whom from time to time I have sailed. I have been for months together at sea 71 enough for the purpose, should pursue the more agreeable path, and travel by land. To others whose limited pecuniary resources, and completely enerva- ted constitutions deprive them of that choice, a re- medy not less efficacious is held forth, by means of a sea- voyage. Lastly, a question yet remains: when it is deemed convenient to make a change of climate, what places are the most proper for the purpose? With regard to the advantages or disadvantages of different places, I shall not venture to state any thing positively, for in fact I am very little conversant in these things. How- ever, this much 1 may say with certainty, that a clear, dry, and at least in most cases, an uniform climate, is required. The southern countries of Europe, — Spain, the greater part of Italy, the southern parts of France, enjoy such a climate; so also does Madeira,^^ and the Bermuda Islands. It is my intention in a future part with four hundred and once with near five hundred souls. Among such a number I could not fail of making many ob- servations, and what I have advanced is the result of them. VI '» It was formerly very common for physicians who ad- sed a change of climate for the purpose of relieving their /' of this work, to say a few words on the use which the physician can make even of the hottest climates, with a view to their remediate eflfects in diseases. These things being premised, I may now treat more in detail of certain disorders arising from our consumptive patients, to send them to the island of Madeira. The high opinion entertained of the salubrity of that place, will appeal from the following passage from Dr. Fothergiii's observations on consumptions.* " Of all the places we are acquainted with, perhaps the island of Madeira enjoys the most equal temperature; but the voyage and other circum- stances attending it, afford very formidable objections;" and Dr. Thomas Reid, in the first edition of his valuable work on pulmonary consumption, recommends Madeira in preference to Lisbon, " as being at a greater distance, more to the south- ward, and the air, from its insular situation, purer and infi- nitely more healthy." In the second edition of his work, however, Dr. Reid tells us that the recommendation of Ma- deira as above stated, was made on the authority of a medi- cal friend who had sent phthisical patients to that island with success, as well as in consequence of what Dr. Fothergill had said respecting it; but tells us that having subsequently made some inquiries on the subject, he " was not a little surprised to hear, that it (the island of Madeira) was believ- • Med. Obser. and Inquir. Vol. V. p. 368. Ann. 1776. ?3 climate. It is by no means my intention to descant upon all the diseases emanating from this source. It ed to be particularly prejudicial to the consumptive." He quotes a letter from Dr. Gordon of Madeira, dated 28th April, 1784, in answer to his inquiries, with a view to as- certain the truth.* Since this place still retains the reputa- tion of being peculiarly suitable for consumptive patients, with some physicians: and since to my knowledge a few pa- tients! have been sent from this country to that island, who died there, it may not be amiss to publish this extract, for the information of those who may be disposed to follow the same practice. Such observations as this letter contains, coming as they do from a physician residing in the island, a physician too of reputation, and enjoying the confidence of some of the first medical men of London at that time: must be read with interest, and cannot fail to receive the attention they merit. " Sir John Pringle, and some others of my medical ac- quaintance in London, did me the honour about eight or nine years ago, to send some of their consumptive patients under my care, of which few recovered; and I was induced to discourage them from sending any more to our island, especially as the generality of these cases are in the last * Reid on Consumption. 2d Edit. p. 271. \ Two from Philadelphia, and one from Virginia, K 74 will be sufficient to take into consideration those in ^rhich a change of climate avails most, and the dan- ger and inconvenience of which particularly demand the assistance of this remedy. The diseases which may be ascribed to the effects of our climate, vary according to the age of the per- stage of the disease before they leave Britain. And unless they are particularly recommended to some British mer- chant's house, they have no alternative, but to take up their quarters in a publick-house, which are very indifferent in this place, and by no means calculated for their reception. No pecuniary consideration whatever will induce the natives to accommodate phthisical patients. Our provisions in general are not bad, though it is often difficult to procure proper diet for the valetudinarians, by having no kind of market established. Our roads all over the island are very indif- ferent, and not shaded. The society is very good for those in health. A great scarcity of asses milk, and no such thing as nurses, or proper people to attend the sick. Add to all these objections, I am of opinion, that our air is too fine and fienetrating for hectic complaints^ and should imagine the south of France a much better climate, or even the High- lands in some of our West India isles. Am sorry the situa- tion of Madeira will not permit me to give you better en- couragement on the propriety of sending consumptive pa- tients here." 75 son affected. Diseases of the breast, principally hae- moptysis, and pulmonary consumption which often supervenes upon it, occur for the most part in youth. In more advanced age these complaints are rarely observed, when various affections of the abdominal viscera, and especially of the stomach, succeed. Gout and hypochondriasis are frequently produced by these affections, and sometimes they are found combined with them. In the decline of life when all the powers of the system have become degenerated, the intem- perate climate falls upon those already debilitated and nearly worn out by old age, — racks every part of the system with innumerable pains, embitters life, and accelerates the approach of death. It is my intention in the following pages to observe the natural order of diseases; and therefore, I ought to begin with pul- monary consumption, which, for the most part, oc- curs in youth. 76 SECTION IL Of the nature and symptoms of Pulmonary Consumption, and its similarity or identity with Scrophula. — Of the different -tiotions of physicians respecting the curableness and in- curableness of genuine Phthisis. — Of the effects of Wounds and other Injuries of the Lungs, on that Viscus. — Of the remote and proximate causes of Consumption, and the rea- sons that may be deduced from them, in favour of a change of Climate upon the Disease. — Of the curative effects of Travelling, Riding on Horseback and Sea-Voyages. There is perhaps no disease generated in this island, whether we behold its devastations or those subjected to its ravages, more deserving of attention than pulmonary consumption. If we may credit the London bills of mortality, a fourth part of our popula- tion is carried off by consumption." This prodigious 17 « In the London bills of mortality, the number said to die of consumptions, is generally between four and five thousand annually; exclusive of those not buried in parochial church- yards, and in every other part of the kingdom. Though the 77 destruction of the human race falls especially upon the youth, often on the most beautiful, particularly of manner of forming these registers, is liable to such uncer- tainty, as calls loudly for reformation; and the term consump- tion is applied to many different diseases; yet it will serrc to demonstrate, that a great number yearly die of this dis- ease. « By a register of the parish of Holy cross in Salop, from the year 1770 to 1780, kept by the Rev. Mr. William Gor- such, it appears, that three hundred and eleven died in the ten years by disease and casualties; out of which sixty-two died of consumption; sixty-four of a natural decay, without any apparent distemper, and thirteen by accidents. So that the deaths by consumption are somewhat more than one in four. By an actual survey made in the year 1780, the inha- bitants were eleven hundred and thirteen. Philosofih. Trans, vol. 72, for 1782."* It will appear from the above account of the bills of mor- tality of the city of London, that the fatality of phthisis is prodigiously extensive; and from what has been advanced in the text, that the disease is endemial to the climate of Great Britain. Now it is a fact that the prevalence and fatality of Reid on Consumption, p. yii. 78 the fair sex, and on those who are conspicuous for wit and the elegancy of their minds and persons. Should consumption in some portions' jf the United States is no less conspicuous and demonstrable than in England. Volney ob- serves that « all travellers in the United States have spoken of the frequency of this fatal disease, which cuts off chiefly young married women and girls in the flower of youth and beauty. It is more common in New England and the middle states, than in the states to the south-west."* Dr. Spalding, in his bills of mortality drawn up at Ports- mouth in New Hampshire, has proved, that as great a num- ber of persons die of consumption, in a given time and in a given population, in the New England states, as die from malignant fevers in the southern states of Carolinas and Georgia. What then is the probable cause of this great pre- valence of pulmonary consumption in these states? I have before (Note 2) hinted at the similarity of our climate to that of Great Britain, and said that a corresponding simili- tude in the constitution of the endemial diseases might rea- sonably be expected to prevail. Let us now take a more extensive view of the nature of this climate with regard to the probable light it may throw on the cause of the dis- ease as above stated. And first let me remark that the un- healthiness of the countries adjacent to our lakes, as well as * Volney*s View of the Climate and SoU of the United States, p. 280. 79 any one however be disposed to doubt that such a deplorable loss can arise from the ravages of a single of some of our eastern sea ports, lying exposed to the sea blasts, seems to be in opposition to the notion of Sir John Pringle, who conjectured that " great bodies of water, such as seas and lakes, are conducive to the health of animals by- purifying and cleansing the air contaminated by their breath- ing in it."* There is no doubt that the different complexion of the diseases of the New England states, from those of the southern, is owing chiefly to the rigour of the climate, ac- companied by rapid and unexpected changes of the weather. These changes of course are ushered in by variations in the winds. In the state of Vermont for example they are gene- rally from the south-west to the north-east, and the most prevalent winds, according to Williams,! are either " paral- lel with or perpendicular to this course." He further states that there the west and north-west winds are dry, cooling and clastick, while those from the south and south-west are more warm, moist and relaxing. In the sudden changes then of winds possessing such different properties, we will find a fruitful source of colds and catarrhs, the forerunners of consumption. What * Anniversary Discourse before the Boyal Society, in the yetr 1773. f History of Verraontj p. 48. 80 disease, let him inspect the bills of mortality of the city of London. Even supposing their calculations What has been just said respectmg the climate and winds of the state of Vermont, is true, generally, of all the northern and eastern states. Yet so versatile is the constitution of the climate of this country, that it is almost impossible to de- fine, by any positive language, its general character. This diversity is not confined to any particular state, or tract of country, but is frequently evidenced in different parts of the same state, and in the same latitude. To understand then tho- roughly the nature of the American climate, one ought to be able to view it in all its multifarious changes throughout the continent. In general it has been remarked that in our win- ters, when a steady cold prevailed from Christmas till March, with much snow and little thaw, and uniformly cold elastick winds: but little tendency to disease was observable; and the diseases occurring during such a state of the weather, were manageable. In a variable winter however, when a warm mid-day sun and rapid thaws are generally succeeded by the nipping frosts of night, and particularly when much rain falls: colds are very rife, and consequently consumptions follow. The greatest danger in this climate however, is to be feared in the months of spring. This is a deceitful season, and never fails to make unperceivcd and deadly inroads on the constitutions of persons predisposed to phthisical com- plaints. Volney has asserted that " throughout the continent 81 are double what they should be, how extensive and in- deed lamentable a destruction of the human race, of North America, there is no spring.'"* This assertion, no- vel as it may at first sight seem to be, is really well founded. There is no part of the United States north of the state of Maryland, where three hours fair weather may be depended on, in the months of March and April; and though Mayf is less variable, yet its excessive heats, and sometimes unsea- sonable frosts, render it so unpleasant a month generally, that it can hardly be considered as spring weather. Compara- tively with Europe, according to M. Volney,| there falls " more rain in the United States, generally speaking, in fewer days, and there are fewer cloudy days, more fair days,§ * On the Climate and Soil of the United States, page i£K). f " The month of May, 1786, will long be remembered, for having fur- nished a very uncommon instance of the absence of the sun for fourteen days, and of constant damp or rainy weather.'* Rush's Account of the Climate of Pennsylvania. + View of the Climate and Soil of the United States, p. 24i, 242, 243. § ** The climate of much the greater portion of the United States furnishes great degrees of heat and cold, in their respective seasons; but neither of the extremes is of long continuance. Our climate is also very variable, the tem-t perature of the atmosphere being liable to great and sudden vicissitudes. Ne- vertheless, taking the whole routine of the seasons, we enjoy a large pro- portion of fine and moderate weather, -with more days of stm-shine and serene sky, than, perhaps, any part of Europe exhibits." — Observations on the duration of Human Life, &c., in a letter from Wm. Barton, Esq., to Dr. Bit- tenhouse. Trans. Am. Phil. Soc. Vol. 3. p. 51, paper No. vii. L V \ 82 •V must we not attribute to pulmonary consumption! If it was worth the trouble of an accurate computation, and more evaporation.*** It is owing to this powerful evapo- ration in the United States, that we have such heavy dews, which are unknown in the temperate climates of Europe. The reason of this rapid evaporation M. Volney believes is « because the winds are pure, in consequence of the general plainness of the surface, and because one of them, the north- west, which is extremely dry, prevails for two-fifths of the year.**t Hence we have another cause for the prevalence of * Mr. J. (now General) Williams* found by a series of experi- ments and researches that the mean quantity of evaporation, at Cam- Inches. bridge, near Boston, for a term of seven years, was - - - 36 While in seven German and Italian cities, on a mean of twenty years, it was only --- 49 Which leaves a difference of-- 7 Yet the cities of Italy are in a latitude much more favourable to evaporation than the vicinity of Boston, adjacent to the Atlantic Ocean. Fair Days. In one year there were at Salem 173 At twenty cities in Europe - : 64 ' ■ Cloudy Bays. At these same twenty cities there were in 1785 - - - 113 At Cambridge, near Boston - - - 69 At Salem, taking the medium of seven years - - ' - - 9l> t View of the Climate and Soil of the United States, p. 244. Transactions of the American Phil. Soc. 83 it would not be in the least difficult to show, that twenty-five thousand men are annually destroyed in consumption. The warm mid-day suns produce copious per- spiration in the spring, and the sudden evaporation of it pro- duces catarrhs. The air of America abounds more in electrick fluid than that of Europe; this fact, which evidences an exces- sive dryness of the air, and which really is only observable dur- ing the continuance of the dry and healthy winds, is remark- ably demonstrated in the appearance of the silk tassels worn on boots, especially when they come frequently in contact with the silk linings of our surtouts. It is constantly observed too, flying off* in sparks, when we pull off worsted or silk stockings. When the atmosphere is thus surcharged with electrick fluid, it is highly salutary. Every degree of diminution in the quantity of this fluid, is an evidence of an increased de- gree of dampness in the air, and consequently, argues a less wholesome quality in it. The changes from this state of air to excessive humidity, are very common, and not unfre- quently very sudden. Hence a reason why we should guard against the colds consequent to them, by changing or in- creasing the quantity of our clothing. The female portion of the population of the middle and northern states, is said to be more subject to consumption than the male. If this be actually the case, and I am inclined to believe it is, we need look no further for the cause, than the recklessness with 84 Great Britain by this disease. The celebrated Syden- ham advanced an opinion respecting this malady, not which the women, and young girls, particularly those ac- customed to move in the gay circles of high life, indulge themselves in imprudent changes of clothing. This is at all times ill-proportioned to the severity of our climate; and when the little degree of comfort and protection it is ca- pable of affording, is wantonly sacrificed at the shrine of fashion, need we be surprised to hear the reiterated com- plaints of colds they make; or can we doubt the assertion, that this sex is peculiarly liable to phthisical complaints. This last circumstance is said by M. Volney to be owing to their " light and airy dress." He says that in the course of two winters, he observed a great number of people of fashion had four or five relapses, " for the rich are particularly lia- ble to colds."* " In the cities on the coast," he continues, " where the people are eager to imitate Europeans, these colds have other causes in overheated apartments, balls, tea- parties, and feather beds; sometimes indeed in the German fashion, that is, a feather bed to sleep on, and another as a coverlid." — The circumstance above stated, respecting the greater prevalence of colds among people of fashion, (for such I presume M. Volney alludes to when he says « th6 rich,") is a notorious fact; and among these, there is no * Volney's View, ke. p. 279 and 280. 85 widely differing from this; namely, that two-thirds of those that fall victims to chronick diseases, arc doubt that the women are more frequently afflicted than the men. It is a fact as notorious too, that it is a common prac- tice among the young girls of this and other cities, to throw off a flannel garment which they have worn all day in the house, and in a warm room, when they go to a dance or tea-party in the evening. This circumstance* of itself would be a fruitful source of consumption, in such a climate as this: but when we add to it the thin and scanty dress which supplies its place, — the imprudent exposure to the cold air while in profuse perspiration after dancing, and what has equally an injurious effect, the thoughtlessness of eating ice-creams while overheated by this violent exercise,— ought we not rather to be surprised that consumption does not sweep away the fairest portion of our population entirely, than doubt the verity of the assertion: that women and young girls in the United States are more liable to consumptions and colds, than any other persons? If then this change of clothing, this imprudent exposure while so thinly clad; and * '* A learned author supposes the imprudent changing of garment destroys more than the plague, famine, or the sword; one would think the ladies dressed in those days as now; wrapping themselves up in the day, and ex- posing their persons to the cold, damp night-air."— Thos. Reid on Consump- tion, p. 394. 86 carried off by pulmonary consumption. In another place he asserts that chronick diseases destroy almost this more than imprudent exposure while overheated by- warm rooms and dancing, are sufficient to produc e such evils in this delicate sex — what fatal danger must they not ex- pose themselves to, by encountering all these hazardous cir- cumstances at particular times, when the constitutional econo- my requires infinitely more care than during the interval of these periods: and when the system, even of the most ro- bust female, is always more or less debilitated and disor- dered! From the foregoing observations therefore, it follows: that the cause of the prevalence of consumption in some portions of the United States is to be found in the inconstant state of the climate as demonstrated in the sudden and excessive transitions of the weather;* the great evaporation and heavy * The range of the thermometer in these states, is not unfrequently from 80** of Fahrenheit in summer to zero, or one or two degrees below it, in winter. And in the present month, (Feb. 1815,) the mercury stood at from 5** to 16® below zero of Fahrenheit in different parts of the United States. My father mentions, that " Mr. Rittenhouse had noticed, that, at his Norriton observatory, (in lat. 40" 9' 31" N.)'the mercury in Fahrenheit's thermometer, not exposed to the sun-shine, but open to the air, was at 941 30', on the 5tli of July, 1769; * which,' says he, ' was the greatest height it had ever been ob- served to rise to, at that place.' But the wnter is informed by a judicious and attentive observer, that at Lancaster, Pennsylvania, w^hich is in lat. 40« 2' 39'' N. (the long, of this borough-town is 5» 1' 4" W. from Greenw.) the mercuiy rose by Fahrenheit's scale, on the 7th of July, 1811, to 97* 30'. Admitting this to be correct, if 1» 30' be then deducted, for the extra heat of 87 a third part of mankind. From these proportions as data, it would appear that pulmonary consumption de- stroys forty thousand men and more, annually in this island. There is however, no occasion to descant upon the devastations of this malady. For there are few of us, who have not to lament the death of acquaintances, dews which follow it; the frequency of checked perspiration by cold winds after rapid thaws of snow; the disproportioned quantity of clothing at all times, particularly of the females, to the rigour of the climate, and the imprudent change of it during the winter season; as well as the careless exposure of the system to the intemperance of the spring weather, by the premature alteration of winter dress, particularly the imprudent change of flannel garments. Among these causes, it is evident that the physical constitution of the country has a most power- ful operation, yet it is equally plain that the defects of climate are assisted in their unhealthy consequences, by the artificial deficiencies in clothing. This proves that with greater atten- tion to the state of the weather, and more care in adapting the the covering of our bodies, to its inclemencies and its ea- pricies: the prevalence of this destructive disease would be in- finitely diminished, and in all probability its violence and fatality- lessened. so large a town as Lancaster in comparison with a country situation, there is in this case the great range of 118" by Fahrenheit's scale, for the extremes of heat and cold in Pennsylvania." — Barton's Memoirs of Kittenhouse, note, p. 13f^. 88 associates, or friends, who have been snatched from us by this destructive complaint. Relentless, cruel and unfeeling — this deadly consumer of human health, glutting itself perpetually upon the young and delicate, fills our country with sorrow and de- vastation! Pulmonary consumption is esteemed an endemial disease in our climate, and not improperly; for per- haps there is no country on the globe in which it produces such fatality. All physicians confess that the most efficient remedies are administered in this disease in vain, at least, in the generality of cases; and that when it is of long standing, a radical cure must be despaired of. The cure even of incipient phthisis, is a precarious and difficult undertaking. No remedy succeeds better in this disease than a change of climate, by means of a seasonable journey into warm countries. Whatever therefore seems to promise any assistance in so dangerous a malady, is worthy of the highest attention. Its mode of action is now to be investigated. By an attention to the symptoms, and to the remote and proximate causes of the disease, as well as from analogy of those things which have the effect of yielding succour to the ma- S9 lady, we may learn how that remedy operates bene- ficially. Pulmonary consumption may be known for the most part, by the following symptoms: a slow ema- ciation of the whole body, accompanied with hcctick fever; a sense of weight or constriction, or pain, in the breast, with difficulty of breathing; a frequent and troublesome cough, which in the beginning is dry, but after the disease has progressed, generally accompanied with purulent spitting. The symptoms which denote incipient consumption, vary according to the causes which produce it, as for instance, pleu- risy, catarrh, haemoptysis, &c. The proximate cause of this disease is well known. Dissections of the bo- dies of persons who have died of consumption, have almost always exhibited tubercles, vomicas and ul- cerations of the lungs, by which sometimes nearly the whole of that viscus is consumed. I say that these morbid phaenomena will almost always occur, for I would not venture to assert that they will al- ways be found. There are many physician^^ of no little reputation, who strenuously contend, that sometimes neither an ulcer nor any other visible injury is to be discovered in the lungs of those who have had co- M 90 pious purulent spitting, and other symptoms of con- sumption, and who had evidently died of this disease. It is agreed on all hands however, that instances of this kind are very rare, while it is generally allowed that true consumption arises from an ulcer, or rather ulcers in the lungs. The dissections indeed of dead bodies satisfactorily demonstrate, that not only a sin- gle ulcer or tubercle, but sometimes congregations of them had produced the disease, and that these had become inflamed and had suppurated. The proxi- mate cause therefore being known, the curative in- dication would seem to consist in dissipating the tubercles, or if they shall have already passed into sup- puration, to heal the ulceration in the first place. This effect however is to be accomplished by the healing powers of nature, and not by the assistance of phy- sicians; and I must confess that in this stage of the disease I see nothing which justifies the expectation of any benefit being likely to result from a change of climate. If the general habit of body is sound, ulcers in any other part are usually healed with facility by the mere efforts of nature; and in such cases physi- cians might easily retard, though they could scarcely promote, the cure. For I do not know any reme- dies which, by any specifick power, can produce 91 > that healing process. It is well known, that many re- medies which have been administered ^vith that in- tention, have had altogether a contrary effect, and not only did not do any good, but often proved very injurious, — such as natural and artificial balsams: and these are now rarely employed. Yet there are certain indolent ulcers, which re- quire the assistance of the physician and the surgeon; and many ulcers that do not heal spontaneously, arc easily cured by the administration of proper reme- dies. By analogy, various remedies have been tried in depraved and obstinate ulcers, consuming the lungs. Of the manner in which the remedies that assist the cure of external ulcers act, it is easy to give the rationale. They divide themselves into two classes: — into external and local, which are applied immediately to the ulcer, and affect that only: and into internal and general, which act upon the whole system, and do good, not only to the ulcer, but also remove any taint pervading the general system. The first are of the greatest utility in curing that par- ticular state of ulcers, which from experience we know retards their cure. As for example, incisions or cscaroticks for destroying fungous flesh, or removing callous parts, or inducing a new and favourable sup- 92 • puration, which are evidently required in healing an ulcer. But it is impracticable to administer reme- dies of this kind in consumption; and even if they could be employed, I know of no symptom by which such a condition of the ulcers could be ascertained, so that either one or other of these remedies could be pointed out as necessary. The other class of remedies (to wit, the general and internal,) exert scarcely less power in curing those ulcers which arise from some general taint. Such are the syphilitick or scorbutick ulcers, which for the most part we may vainly expect to heal by purely local means, unless, at the same time^ internal and general remedies adapted to the cure of those dis- eases, are carefully administered. By analogy, there- fore, in this malady, arising from ulcers difficult to to heal, remedies should be administered for curing that taint, of whatever sort it may be, which impedes the curing of such ulcers. In order properly to ac- complish this purpose, it is necessary to ascertain the remote causes of the disease. It is not necessary to expatiate largely on the subject, to show that con- sumption does not, at least? generally, arise from a inere injury or even from suppuration of the lungs. 93 unless some morbid predisposition or taint shall pre- viously have existed in that viscus, or in the general system. What that taint is, will hereafter be investi- gated. It is known, however, that this disease gene- rally supervenes upon haemoptysis; so that whenever a young person is aflected with a spitting of blood from the lungs, his case is hopeless. Sometimes also, consumption follows a badly treated peripneu - mony or pleurisy which has terminated in suppura- tion. Sometimes too, though rarely, it arises from some great external violence, inflicted on the breast or the lungs themselves. These things having been ob- served to take place, it has been hastily concluded, that an injury and a certain depraved suppuration of the lungs, as well as an incurable ulcer, and conse- quendy a mortal consumption, were produced. Physi- cians have referred the cause of this injury, to the na- ture and construction of the lungs, and their office. In support of this opinion they have remarked, that the blood flows with great force through the lungs, and that they themselves are agitated by a perpetual motion, namely of respiration, which by alternately weakening and irritating its parts, was believed to impede the cure of a wound. And finally they have adduced another reason from the analogy of external 94 wounds, which are difficultly cured when exposed to the air. Now the air, say they, is received into all i>arts of the lungs; if therefore there be any ulcers there, they are necessarily exposed continually to it. But all these circumstances are not sufficient to solve the dif- ficulty. The motion of the individual parts of the lungs is always inconsiderable, and except in a full inspira- tion, scarcely sensible. It seems hardly probable, therefore, that such injury should arise from this cause. And no effect should be attributed to the ad- mission of air; for, although it is received into the lungs, it never comes in immediate contact with them, since the internal surface of this viscus is always lubri- cated with mucus, which would naturally defend any wound from the air. Besides, we know that the exter- nal wounds of dogs, and many other animals, heal after being licked; for this very reason, that the saliva and mucus mixed with it, sufficiently defend the wounds from the action of the air. All arguments therefore, tending to show that an injury of the lungs ought to produce consumption, go for nothing. And besides, experience proves that the fact is not so. For there are innumerable examples of cures, where, after the most manifest injuries, nay, even suppuration, of the 95 lungs, no consumption ensued. ^^ Many persons also have been affected with haemoptysis, without con- ^8 A very remarkable instance of entire recovery from a wound into tlie cavity of the lungs, is related by Dr. May,* of Plymouth, in England. The case was that of a British officer, who was wounded in a duel. The pistol ball passed in the di- rection of the right lobe of the lungs, through which it was supposed to have perforated. Considerable external haemor- rhage and bloody expectoration with difficulty of breathing came on; these were followed by a cough and symptoms of violent inflammation. The antiphlogistick plan of treatment was pursued. Blood was discharged for many days by coughing, and purulent expectoration supervened. Symptoms of conva- lescence soon after appeared, and the patient in a short time entirely recovered. Dr. May says he was indebted for this fact to Mr. Adams, of Likeard, an ingenious surgeon of the navy, who was an eye witness of the circumstance. That the ball actually perforated the lungs in this case, was proved by a circum- stance which subsequently occurred. A piece of woollen cloth, enveloped in a clot of blood and pus, was brought up by coughing. That consumption did not follow seems plain, but in all likelihood the patient owed his escape from it, to a circumstance which, though no mention is made of it, in all human probability really existed: I mean a sound and robust constitution, unblemished by any latent pulmonary taint. I am the more inclined to this opinion, from having had • Essay on Pulmonary Consumption, b) Wm. May, M. D. Intror'. p. xiu. 96 sumption supervening. Many ^fter an attack of badly treated peripneumony, have had an extensive suppu- under my own care a case strikingly similar, as far as respects the nature of the wound, though followed by very dissimilar results. As this kind of wounds of the lungs is always inte- resting, I will briefly relate the instance I allude to, which 1 the more willingly do, as perhaps I shall never have another fit opportunity of making it publick. While I was surgeon of the frigate United States, in the year 1809, being on shore at Norfolk, where the ship was then stationed, I was called to visit midshipman L h, whom I had but an hour before seen on board, in perfect health. He was so unfortunate as to have been under the necessity of meeting a brother officer in the field. »His antagonist's ball (being one of the largest pistol- size, since the arms used were ship*s arms) had entered the ieft side of the breast and had passed entirely out under the inferiour edge of the scapula; its direction being obliquely upwards and backwards from the point where the ball en- tered to the place of its exit. I found him bleeding pretty largely from the external wound in the breast, and copiously expectorating blood, likewise coughing it up at short inter- vals, in large clots. He was labouring under great difficulty of respiration, and at times seemed nearly to be suffocated with the rapid and extensive internal haemorrhage. His coun- tenance had a ghastly paleness, which, together with the deadly hue of his lips, and other symptoms, seemed to in- dicate that he was fast approaching dissolution. It is needless to go into the detail of the treatment pursued. Suffice it tosay* 97 ration in the lungs, which being entirely rejected by spitting, was soon cured. And finally, examples that it was rig^orously calculated to allay the great irritation of the system while it continued, and subsequently modified and altered as the exigencies of the case required. In a short time, extensive suppuration, with a constant cough came on, and continued for a long time to weaken the patient. Hectick fever with colliquative night sweats now succeeded, and seemed to threaten a fatal termination to the life of this inte- resting youth. He however survived the accident, a circum- stance chiefly owing to the kind and close attention of his brother officers of the ship, whom commodore Decatur per- mitted to be as much on shore to nurse and watch with him, as the duty of the ship could admit of: an office, as he was much beloved, that they all cheerfully performed, and in ■which they showed their usefulness by a prompt and correct execution of the directions of his medical attendants. In the month of February, 1810, the United States proceeded to sea, and Mr. L. was s6nt to the Marine Hospital under the care of Dr. Barraud, who showed him every possible attention and kindness. In the month of April, 1812, while visiting the navy- yard at Washington, I accidentally met him. He had been with his friends in the country, and his general health was considerably mended, though it was plain to me that he la- boured under a pulmonary affection. He is still living, I be- lieve, though I fear he will never shake off the disastrous consequences of his accident. His stature, the confof- N 98 daily occur where the lungs are injured by external violence, or wounded, and yet consumption rarely arises from these causes. If the wound be extensive, sudden death entirely prevents all danger of con- sumption: if it be slight, it is soon healed. Indeed, there is one instance of a wound in the lungs proving mation of his chest, his voice, his complexion, even in health, strongly indicated I think, a predisposition to phthisis. Conse- quently no one will be surprised to hear that it supervened eventually. This might with propriety be classed with the phthisis ab vulnere of Sauvage, and the " phthisic par bles- sure de poitrine" of Bonnafox Demalet.* Drs. Barraud, Sel- den and Hansford, physicians of Norfolk, saw this gentleman with me in the first instance: he had then been wounded about half or three quarters of an hour. The two first and my- self continued to see him for two weeks or more, and the latter part of the time Dr. Selden and myself continued in at- tendance together. The case of this young man is well known to Dr. Gerard Dayers, now surgeon of the Congress frigate, and Dr. William Clarke, at present surgeon of the Wasp sloop of war: both at that period my mates on board the United States. * This nosological writer places this variety of consumption, as the sixtli species of the third genus of the disease. His first genus contains four species; his second, ten; his third, six. — Vide " Traite sur la nature et le traUement de la Phthisic Pulmonaire," by this author. 99 a cure instead of the cause, of , phthisis. A military commander who was believed to labour under a pul- monary consumption, was wounded in an engage- ment, the ball having passed through his lungs. This remedy, a harsh and dangerous one it must be confessed, succeeded most happily; and the man lived many years afterwards, and is yet living, free from every consumptive symptom. Consequently^ in order to cure a suppuration of the lungs, there is no necessity for the use of remedies which pro- mote directly the healing of the ulcer itself, if any there be, endowed with such a virtue. And we see nothing in an ulcer of this nature, requiring a change of climate. The assistance ofthe physician is no further necessary, than in seeing that the morbid taint which renders the ulcer incurable, whether affecting tlie lungs only, or contaminating the general system, be first removed: when that is banished, the ulcer will be easily healed. For the healing powers of nature alone effect the cure of an ulcer in the lungs, as in other parts of the body, when every obstacle is removed. All these facts plainly prove, if I am not mistaken, that a simple injury of tlie lungs, and a rupture of their vessels, can never induce an incurable ulcer 100 and pulmonary consumption, unless the lungs them- selves or the general habit, have previously become contaminated by some taint. But the nature of this predisposing vice can only be ascertained from ob- servations of the causes of the disease. Experience therefore teaches us, that those persons will be most liable to consumption, who have received an here- ditary taint from their parents; who are between the age of puberty and thirty-five years; who have a deli- cate and weak habit, a contracted and narrow chest, a deformed spine, and shoulders projecting dispropor- tionably beyond the arms; who have a white and smooth skin and delicate complexion, long neck, weak voice, and frequent hoarseness from slight causes, together with a sanguineous, phlegmatick temperament: and finally, those in whom there is a scrofulous and hasmorrhagick disposition, and who are very liable to catarrhs. These signs, indeed, give evidence of the weak habit of the whole system: but especially denote a mal-conformation of the lungs. The chief and most frequent causes of consumption, however, if I am not mistaken, may be reduced to three; to wit: a scrofulous disposition, haemoptysis, and catarrh. From whichever of these the disease 101 arises, I shall endeavour to show, that a change oi" climate promises great assistance. All physicians know that this complaint very fre- quently arises from a scrofulous disposition. The illus- trious Mead advanced that opinion many years ago. Indeed, we owe to Sydenham a memorable remark, which seems to have suggested this; namely, that in some consumptive persons who had been cured by riding^on horseback, glandular tumours in the neck which bore a strong resemblance to scrofulous swel- lings, have been observed after that disease had left them. No doubt, however, remains on this subject among physicians of the present day. Observations have satisfactorily ascertained the fact, that persons of scrofulous habit are more subject to consump- tion than others, and that the greatest part of con- sumptive people evidently have this disposition. There are some physicians too, of no little reputation, who, out of every hundred patients carried off by con- sumption, reckon the proportion of ninety at least, to be scrofulous. Besides, there is certainly a great similarity and affinity between the tubercles and con- sumptive ulcers of the lungs, and scrofulous tu- mours and abscesses in other parts of the body. 102 They also have the same external, and, if they be cut by the knife, the same internal appearance; the same thickness and hardness. In the same way they often increase by degrees from a small* beginning to a large tumour, and generally without much pain or inconvenience; they suppurate tardily and with difficulty, and never pass into a healthy suppura- tion, but are resolved into offensive and almost in- curable ulcers. Both appear at the same seasons of the year, that is, in winter and the spring; upon the approach of summer they are mitigated or discussed; and on the return of spring both often reappear. And lastly, in dissecting the dead bodies of those who evi- dently died of scrofula, scrofulous tumours in all parts of the bodies, and tubercles in the lungs of the same kind, have not unfrequcntly been found; this it has happened to me to see twice or thrice. From all these things il is sufficiently evident, that consumption of the lungs often arises from a scrofulous disposition, and that it is a true scrofulous disease. Wherefore, when consumption occurs in those, who are either manifestly scrofulous them- selves, or born of scrofulous parents, it is generally to be attributed to this cause. 103 Perhaps some may believe that it would not avail much in this complaint, that its cause should be es- tablished by the most unequivocal symptoms. For scarcely any disease is more obscure or more diffi- cultly cured than scrofula, even when it affects exter- nal parts, to which remedies adapted to the disorder, can be directly applied. Indeed I honestly confess that almost all remedies are for the most part exhibited in vain, and from their effects I have never been able to collect any thing that argued a probable advantage from a change of climate. Neither can much be ga- thered from the causes, for nothing is more obscure than they. There are various opinions with regard to the proximate cause of scrofula: some attribute the dis- ease to a lentor and other vitiated properties of the lymph; others think the vice is not in the lymph, but ' depending on the lymphatick vessels themselves, and which they believe arises from various causes, as debi- lity, laxity, and preternatural enlargement. Others think the disease arises from some morbid matter, either engendered in the system, or received from pa- rents, which by some .inexplicable process is secreted from healthy fluids, and deposited in particular parts 104 of the body, especially the lymphatick glands. There is no necessity to expatiate in this place upon these diverse notions; for whether they be correct or incor- rect, unless they be more accurately investigated, no curative indication arises out of them, which calls for a change of climate. The remote causes of this disease are not any better understood; for it is not agreed among physicians whether a slender diet, consisting principally of fruits and the like, similar to that of the poor, and especially of the country people, should be freely used; or wliether a more generous diet and abounding in the luxuries of the rich, is best suited to this disease. I will not venture to assert that scro- fula arises from the effects of any particular climate: for it is scattered throughout the terraqueous globe. It is known in all regions, whether cold, or warm, or temperate; and every age has witnessed it. Universal as this plague is, yet, if I be not deceived, it is most common in cold moist countries; and of rare occur- rence in temperate and dry ones. From the observa- tions of some of our physicians who have travelled in Italy, this disease is more rare there than in our island. It is also more rare in Spain. A very intelli- gent man, who practised medicine many years in Cadiz, replied to my enquiries on this subject, that 105 he had seen very few persons there labouring under this complaint, ^nd none affected with rickets, a dis- ease which many physicians imagine to be nearly al- lied to scrofula. But I have known other physicians to affirm that scrofula was quite frequent in Spain. From these things, therefore, scarcely any thing can be ga- thered until the fact is more accurately investigated. There are some who strenuously declare that this complaint is more frequent in Ireland than in Great Britain; and in the western parts of this island than in the eastern; a circumstance that can be attributed to no other cause than the greater humidity of those parts. And indeed in this island, so far as I am able to ascertain, it is more frequent in moist places than in dry. It is therefore probable enough that a scrofu- lous patient would receive some relief from travelling into dry and moderately warm countries. This will perhaps appear a very uncertain expectation; but if I am not much deceived, it is greaUy strengthened by the history of the disease, and by analogy of those things that have an useful or pernicious influence. Although scrofula rarely falls upon the lungs be- fore the patient has reached the fifteenth year of his age, yet generally it is found much earlier in other O 106 parts of the body, especially in the glands of the neck. Sometimes indeed, and not rarely, no symp- tom of scrofula is observable, until tubercles arc formed in the lungs, and consumption has com- menced, which doubtless had arisen from this source if the patient should have had an hereditary taint, that is to say, born of scrofulous parents. When scrofula shows itself in external parts of the body, it is for the most part between the fifth and twelfth year, and some- times, though rarely, it aiRicts the unfortunate vic- tim even from its infancy. Sometimes also, but very rarely, it appears in more advanced age. When the dis- ease occurs but once, mostly about the age of puberty, it is cured by the efforts of nature, and spontaneously disappears; and never after does it trouble the pa- tient, unless unfortunately it falls upon the lungs, and produces consumption. How this relief is effected, I confess I do not know. Great changes are pro- duced in the human constitution at that period, which are not accurately understood: but by these changes alone, many diseases are entirely cured. This is a remedy therefore that we can with difficulty comprehend, and never be able to imitate. But another most efficacious remedy in this disease, and not an artificial one but produced by nature, it is acknow- 107 ledged we'can imitate by a change of climate. It is uni- versally known, that external scrofulous tumours are not always stationary, but at one time are augmented, at another diminished; sometimes vanish, and after- wards reappear. These changes are observed to be produced by the different seasons of the year. Scro- fulous swellings begin, for the most part, about the winter solstice; in the spring they are increased; but upon the approach of summer their augmentation ceases; during the summer and autumn they disap- pear, or at least become very much diminished; and on the return of winter they are reproduced. Frequently too, when these tumours suppurate and produce foul ulcers, they will not yield to any reme- dies, but, on the approach of summer, they sponta- neously heal. Now tubercles in the lungs, as far as we are able to learn from various symptoms, are ob- served to be affected in the same way by the different seasons of the year. For the patients in the winter or spring are often affected with a slight, frequent, trou- blesome, and dry cough, and difficult respiration. From these symptoms, especially in those of scrofu- lous disposition, consumption is always to be feared. Yet not unfrequently they spontaneously recede dur- ing the summer season, but return in autumn or in 108 winter; and upon the advance of spring, death carries off the patient. Is it not therefore highly probable, that the winter season is extremely injurious to all ulcers and scrofu- lous tumours wherever they may be seated? It is not altogether unlikely either, that the severity of a cold climate supplies certain remote causes, both ex- citing and predisposing, of the disease. And if we ad- mit this, by analogy it must be granted: that sum- mer, or a moderately warm climate will remove, or guard against those remote causes, so that every obstacle to the resolution of the tumours and the healing of the ulcers being removed, the healing powers of nature would overcome the disorder. The disease lurking in the constitution generally falls upon the weak parts. Now, moderately warm air is favoura- ble to respiration, and invigorates the lungs: why then should we not think that a moderately warm climate would in this manner overcome consumption, or in some other hidden way would ward off the proxi- mate causes of the disease? But in whatever manner the injury has arisen; whether winter gives rise to the remote causes of the complaint, or only exerts an injurious effect upon the disease already existing: it 109 is clearly evident, that the danger can be avoided in no other way than in flying from the intemperance of the winter season, by travelling into warmer countries. If the patient should undertake a journey into suita- ble countries, where he could sojourn for a sufficiently long time: he might enjoy a perpetual summer throughout the whole year, or if necessary, for many years together. Thus might all the inconveniences of our long winter be avoided; and whatever good is received from our summer, might be thus derived at pleasure from the summer season of foreign countries; and we might expect, not only that a stock of health would be procured, but also that it would be greatly augmented. And indeed to me it does not by any means appear absurd to expect, that if a summer lasting for four months exerts so powerful an influ- ence as to heal scrofulous ulcers, dissipate tumours, and in fine, drive away the disease for many months; a perpetual summer would not only hinder the return of the complaint for a long time, but also change the whole habit of body, and radically extir- pate the scrofulous disposition, so that all danger of scrofulous consumption afterwards supervening, would be entirely prevented. It cannot be objected to these arguments, that scrofula is sometimes found 110 in warm countries: for it is well known that climate exerts much more powerful eifects upon foreigners than upon natives. When the constitution is accus- tomed to much heat, certainly it does not derive much advantage or inconvenience from it. If there- fore heat is a remedy for the disease, the more one is accustomed to it, the higher is the degree of it that may be employed; and perhaps nothing else is requisite to cure the scrofula of Spain, than a journey into a still warmer climate. All these circumstances are greatl} confirmed by observation of the effects which experience shows to result from a change of climate, in curing or pre- venting incipient consumption. Many of our inhabi- tants every year, who have every symptom of inci- pient tubercles in the lungs, seek milder climates upon the approach of cold weather, where they remain one or two winters. Some are relieved altogether from the disease, and return to their native country healthy and robust, and never afterwards perceive any sign of consumption. Whilst others, who have tarried abroad only one winter, return home believing themselves cured: but in the first winter they are seized with their former complaint, and die in a short time. If Ill then a change of climate exerts such a mighty in- fluence in curing this disease, that it can remove or dissipate tubercles already formed: how much more powerfully ought it hot to operate, in preventing them. And so the fact is: for though scrofula some- times occurs in the warmer climates,'^ yet consump- tion of the lungs is rarely observed. It is reasonable therefore to expect, that our scrofulous patients who have gone abroad into such countries before the phthisical age, will be free from consumption. From all these facts it appears very evident to me, that a change of climate promises the most advantageous effects in curing and preventing phthisis pulmonalis, arising from scrofula; but certainly it is much better to guard against a disease so dangerous, than to con- tend with it when already formed. — The learned Mead long ago advanced a similar opinion, in his most excellent medical maxims and precepts, respecting the use of a change of climate in guarding against *^ This disease is very common in Mexico. Indeed it appears to be a more common complaint than is generally imagined. Professor Barton says, in his lectures on the Practice of Phy- sick, that it is an extremely common disease among our North American Indians. This fact, which the professor has 112 consumption in persons of scrofulous habit. I shall here quote his words: ** A change of climate often substantiated by the most satisfactory proof, seems, if we ad- mit the identity of scrofula and consumption, in direct opposition to the assertion of his predecessor in that chair, the late Professor Rush, who says this last disease " is un- known among the Indians in North America."* Dr. Bar- ton says, that it is a complaint very rife among those tribes the most remote, and who have little or no intercourse with the whites, and that its fatality among the Onon- dago Indians of the state of New York, has nearly extermi- nated that tribe. There is every reason in favour of this asser- tion; for, that scrofula does afflict them is incontiovertibly proved, and where this disease is found, phthisis pulmonalis cannot be a stranger. It will appear from the text above, that Dr. Gregory was not very sanguine in his expectations of the radical cure of scrofula by a change of climate; and in those particular stages of the disease in which he hints its ineffi- cacy, there will be found but little indeed, to cause a difference in opinion from this learned author. The basis of the hope of curing scrofula by a change of climate, rests undoubtedly on the fact, that an atmosphere surcharged with moisture, is highly favourable to the production or evolution of scrofulous symptoms, when they have not yet appeared, and to the evi- dent aggravation of them, when the disease is already formed. The change from a climate possessing such unpropitious *• Thoughts on the Cmuse and Cure of Pulmonary Consumption. 113 affords heafth, especially if there should be danger of the disease (that is scrofula) falling tipon the Itihgs; qualities fot* the scrofulous, to one endowed with an irhiforia dryness and elasticity with a view to cure or alleviate the disease, is far from chimerical. In my practice on ship boardf, I have seen actual benefit from such a change, and have had one or two cases of very troublesome scrofulous ulcers ol the arms and legs, which resisted pertinaciously every cflRor^ to heal them, but rapidly healed under the same remedies after a change of climate, and even under the disadvantageous effects of a less healthy and pure diet, than that Which the? patient had used in port. The experience I have had withf this disease is indeed but limited, for scrofula is far from tf common complaint among sailors, though more frequent thstrf consumption: yet it has been such as to induce me to believd that more relief m^y reasonably be expected from a changed of Climate, even in the more advanced stages of the disease, than Dr. Gregory is inclined to think. I know not indeed, whether the sea-sickness itself has any good effect on obstinate scrofulous ulcers— perhaps not — but this I know, that in the' cases 1 allude to, the ulcers exhibited very soon after going to sea, a much more healthy aspect. I know further, that glandular tumours are undoubtedly diminished by this sick- ness. I have four or five times seen the detumescence of swel- lings in the neck which I apprehended were strumous, takd place during a few days of rough weather, and twenty ti'me^ and more have I observed the dissipation of venereal buboes- p 114 provided that the patient chooses a country not too warm, nor too cold, nor an unhealthy season, for the from the same cause. I have remarked too that in those cases where these buboes became diminished, the subjects of the disease were mostly landmen^ who having been never before to sea, were violently affected by the motion of the ship, being for days together vomiting, scarcely without intermission. Dr. Barton mentions in his lectures, the case of a young gentleman who came under his care in this city, for a goitrous swelling. The doctor, after recommending a va- riety of remedies, which were ineffectually tried, advised a sea voyage. This was performed, but without any relief; another was undertaken to New Orleans, where the pa- tient, after being attacked by a malignant fever, reeovered from his first complaint. The disease of goitre bears no small relation to scrofula, and a moist atmosphere has no little agency in generating it. The theory of Dr. Barton with respect to this complaint, and which the Doctor has ve- rified by a few but strong corroborative facts, refers its origin to the same* causes which produce intermittent and other fevers. The activity of moisture in marsh exhalations, is well known. How reasonable then the hope that this singular and, in the female sex particularly, this very unseemly complaint, would derive much benefit from a change of climate to one of a dry atmosphere! But to return to scrofula. I have said the foundation of the hope of relieving scrofulous patients by a * Vide Memoir concerning the Disease of Goitre, &c. Philad. 1800. p. 57. 115 change." Under the protection of such a name, I repeat my opinion with confidence; nor am I change of climate^ is built on the acknowledged pernicious agency of moisture on the disease. In corroboration of this, I will quote a passage from Dr. Russel's* valuable work on this complaint. ^< The disadvantages of a bad climate, and of an unfavourable local situation, can only be radically sur- mounted by changing the place of residence to one more sa- lubrious; or, if such a change is not practicable, by adopting the best artificial substitute to correct the inconvenience. As cold and moist air is found to be so highly prejudicial in scro- fula, we endeavour to substitute an artificial atmosphere, which may be warm and dry, and which therefore may, as far as possible, counteract the pernicious tendency of an inhos- pitable climate. Artificial fires are equal to support a mode- rate and proper temperature within doors, and persons of de- licate constitutions, who are threatened with an attack of scrp- fula, ought to be permitted to go abroad in winter only for a short time at once, so that they may not be chilled, nor suffer any injury from long continued exposure to cold and damp air." In another placet l^r. Russel attributes so much good effect to the influence of regular and continued exercise in preventing scrofula, that it would seem as if the doctor had kept in his mind the exercise produced by the motion of a ♦ Treatise on Scrofula. Edinburgh, 1808. p. 59. t Ibid. p. 52. 11.6 ashamed that my conclusions should be rendered sound in this manner. With regard to the benefit that may be expected in scrofulous consumption, from the exercise itself of the journey, I shall not pre- sume to advance any thing from experience. But cases related by Sydenham show, that exercise pro- duces the happiest effects on this complaint. Relief and assistance therefore, might be expected from the exercise of the journey itself, in this, as in many- other diseases. Another, and not unfrequent cause, of consump- tion, in this island at least, is hasmoptysis. How it pro- duces consumption, I shall not undertake thoroughly to explain; since however, experience has taught that phthisis pulmonalis generally succeeds haemop. tysis, I have no doubt but that this might be as- vessel at sea, when he wrote as follows: << The exercise of per- sons studious to ward off an attack of scrofula, ought to be re- gular, moderate, and long continued, sufficient to dispose them to rest, but not of incurring that degree of fatigue whiph would excite a temporary fever, or permanently impair the strength. It seems immaterial what kind of bodily exercise is preferred, provided the above-mentioned circumstances be properly attended to by the patient." U7 signed as the cause of consumption. Certain physi- cians, as we have mentioned above, think that a mere rupture of the blood-vessels, such as occurs at least generally in haemoptysis, produces an incurable ulcer and consumption; for by the violent circulation of the blood in the lungs, and their continual motion in respiration, and the free access of air, the wound is kept open, and its healing perpetually obstructed. It is not necessary to repeat the arguments by which this opinion is refuted. Experience satisfactorily proves, that consumption does not happen at least in piost cases, from a mere rupture of a blood-vessel in the lungs, nor indeed from suppuration itself, pro- vided that viscus had been previously sound. Others assign another and indeed much more probable cause of the disease: namely, that the blood effused into the lungs from ruptured vessels is not intirely ^ejected by coughing, but some portion of it remain- ing in the lungs, is there putrefied, and irritates and corrodes the neighbouring parts, and at length pro- duces a foul and incurable ulcer. I do not doubt, but a great deal of injury might arise from this source: yet if I am not mistaken, that injury rarely happens, unless the lungs have been previously affected with some taint. Fpr in other parts of the body, provided 118 the constitution be sound and vigorous, blood effused in the cellular texture, is soon absorbed with- out any injury or danger. I have seen the arm, after blood-letting unskilfully performed, covered with a livid hue from the wrist up to the shoulder: yet neither suppuration nor gangrene arose from it; the the blood spontaneously disappeared, so that after twenty days no trace of the affection was left. Often also, there are no ulcers formed in the lungs after haemoptysis, although it is hardly probable that all the blood effused ,in them is expectorated by coughing. If therefore no such injury is produced after haemoptysis, it is probable that the effused blood not rejected by spitting, has been taken up by the absorbent vessels. But if, from some cause or other this is not effected, we may readily believe, that an ulcer and other bad consequences might arise from the putrefaction of blood effused into the cellular substance of the lungs. Besides, such a load in the lungs would without doubt excite frequent coughing, than which nothing contributes more to produce consumption, as will afterwards be proved. Lastly, there are some who inculcate the notion 119 that haemoptysis is not the cause of consumption, but only a sign and effect of its cause.^° They be- lieve that phthisis arises from tubercles in the lungs which had for a long time existed before haemop- tysis begun, and which they affirm, brought on that disease, or rather symptom; in other words, the blood- vessels being so compressed by their own mass, that the blood is disembogued either by transudation or from ruptured vessels, into the lungs. Dissections also of dead bodies plainly show, that tubercles, whether scrofulous or produced by other causes, are a frequent cause of consumption, or at least accompany it; and it appears from observations that tubercles 20 An ingenious French writer, whom I have before quoted, and who has taken particular pains to refute the reasoning and arguments advanced by Dr. Thomas Reid and others, in fa- vour of the use of sea-voyages in pulmonary consumption, after strenuously opposing the mode of cure recommended by Dr. Reid, by means of emeticks, and asserting that it is pre- dicated on a false theory of the disease, asks with a tone of great self-conviction: ** quel est le medecin a gut il soit encore fiermis dHgnorer que cea fihlegmes^ que cea mucoaites, que ces oollea aont l^ effect et non la cauae de la phthisic? — Traite sur la Nature et le Traitement de la Phthisic Pulmonaire, par Julien BounafoK Demalet, p. 170. 120 arise in the lungs from other causes besides a Scro- fulous disposition. Certain mechauicks are very much exposed to dust from the nature of thtrf trades; as for example, those engaged in grinding flour, cutting stones, hackling flax, and other similar occupations, arc very liable to tubercles in the lungs and to pulmonary consumption; nor can this be im- puted to any other cause than the dust which they daily receive into the lungs. Yet I can by no means believe, that consumption does not arise from hae- moptysis, unless tubercles have previously existed in the lungs: for in the dissections of the bodies of those who died of this disease, a large ulcer is often found, but no tubercles; many phthisical pa- tients also, after an attack of haemoptysis, are carried off*, who before this seized them, had never exhibited any signs of tubercles. Sometimes also, after a badly treated peripneumony whic h has ter- minated in suppuration, a genuine consumption of the lungs follows, although there had before been n6 signs of tubercles. And sometimes, though rarely, consumption is produced by great external force in- flicted on the lungs. In the proximate and remote causes of hsemop- 121 tysis then, and in the state not only of the lungs, but of the whole system, which precedes and accompa- nies it — is to be sought the reason why phthisis pul- monahs succeeds this complaint. From the observations of physicians it satisfacto- rily appears, that a disposition to haemoptysis is often received from parents; hence it is evident, that the disease does not derive its origin from any slight or accidental cause, but from the formation and peculiar constitution, as well of the lungs, as of the whole body. For it is well known that parents often transmit their temperament and peculiar conformation, to their offspring: and, at least in many cases, we see by an evident deformity of the chest, that a defective struc- ture of the lungs exists. Wherever such a formation occurs, the lungs are never properly distended, and the motion of the blood through them is obstructed; hence arise an irregular circulation and congestion which weaken and distend the blood-vessels, and render them liable to rupture. Many of the exciting causes which frequently produce haemoptysis, evi- dently induce a congestion of blood in the lungs. For example: violent exercise, or great straining of the body as in running, or in lifting great weights; Q 122 - immoderate coughing, vociferation, singing, &c. Be- fore the blood is discharged, the most evident symp- toms of irregular determination and turgescence of blood in the lungs, are almost always observed: such as a sense of weight, or heat, or uneasiness, or pain in the breast, and a redness of the cheeks. Upon the discharge of blood, all these spontaneously, and generally very soon, disappear; and often by a seasonable blood-letting, the haemorrhage is alto- gether prevented. It has been observed also, that signs of spasmodick constriction of the extreme ves- sels, precede and accompany haemoptysis. Some- times a sudden application of cold to external parts, especially if the body has been previously heated, produces haemoptysis: and all physicians know that nothing conduces more to prevent and cure this, than promoting and restoring the due determination of the fluids to the surface of the body. It appears plain therefore, that an irregular determination and congestion of the blood in the lungs, produces hae- moptysis; wherefore it is now to be inquired, how that irregular action is produced, and why the blood is determined to the lungs in such an increased \^ quantity. 123 Experience shows that haemoptysis happens es- pecially to those who are accustomed to high living, and who have changed from a more active kind of life, to one of an indolent and more sedentary na- ture; but most of all to those in whom some cus- tomary excretions, particularly of blood, existing either naturally or preternaturally, have ceased: and of this kind, haemorrhages from the nose, and in females, the menses, are the principal; to these might be added an omission of a customary blood-letting, and sometimes, though rarely, suppressed piles. Hae- moptysis also is observed to happen oftener in the spring of the year than at any other time; and for the most part to men only between the eighteenth, and thirtieth, or thirty-fifth years of age, in which period a plethorick state is known to exist from various symptoms. It cannot then be doubted, that haemop- tysis may arise like all other haemorrhages, from plethora, and therefore the causes of that plethora which produces this complaint, will now be briefly related. During infancy, when the body is daily growing, there is the greatest abundance of healthy blood, which is required for nourishing the system, and sup- 124 porting its growth. This indeed is a true plethora, yet never of an unhealthy kind. At that period, the ves- sels easily yield, and are dilated, until the body has arrived at its proper size; but when the vessels have become stronger, and resist the blood, then plethora is perceived, and haemorrhages and other diseases are produced by it. From the observations and experiments of the ce- lebrated Winthringham, junior, it appears: that a different proportion of thickness and strength of the arteries and veins takes place at different periods of life. In infancy, and also in youth, the veins possess much more strength and thickness than the arteries: in more advanced age, the arteries obtain in their turn the greatest strength. The proper equilibrium is observed to take place about the thirtieth or thirty- fifth year. Hence, if plethora exists in the system before the patient has reached his thirtieth year, it shows itself only in the arteries, or at least particu- larly in them; because the veins, from their greater thickness and strength, are able to resist an exces- sive fulness of blood: but the arteries, from their greater laxity and weakness, receive too great a proportion of blood, and therefore become distended. 125 Thence arises congestion; and upon any sudden and violent action which greatly disturbs the distribu- tion of the blood, a rupture of the arteries and con- sequent haemorrhage is produced. After the thirty- fifth year, haemorrhages of the veins generally occur, but rarely of the arteries. When the increased arteries are full of blood, and yield naturally and equally to the strength of the veins, and all parts of the body daily increase, no inconvenience can arise from that natural ple- thora. But when the growth of the body ceases, and morbid plethora follows, haemorrhages ought first to appear in that part of the system which has first reached its proper size. Hence at that period haemorrhages are to be expected in the head, because this part, as is well known to all physicians, painters, and statuaries, receives its full growth before the other parts. And this is the fact: for haemorrhages of the nose are found to occur before any others, and generally indeed, from the fifth to the eighth year. But when all parts of the body have attained their full size, the reason for haemorrhages happening most frequently in the head, ceases to exist. Then the veins, possessing as yet more strength than the 126 arteries, haemorrhages ought to happen especially in those parts in which the blood flows with the greatest fulness and force. Hence appears the reason why they happen at that period in the lungs: for the same quantity of blood flows through the lungs as circu- lates through all the rest of the body. If therefore, the distribution and equable circulation of the fluids should from any cause be very much disturbed, it is evident that all the ill consequences arising thence, would be felt particularly in the lungs: for however small that viscus may be, its blood-vessels always contain a great quantity of blood. A still larg(^r quan- tity, or even a greater impetus of the blood, could not be borne without danger. They are consequently easily ruptured, and hence arises haemoptysis. But afterwards, when the arterial system has received more strength than the venous system, that is, when man has passed his thirty-fifth year, hzemorrhages from the lungs, and indeed from the arteries in any part of the system, should not any more happen. And the plethora, if any exists in the system, is felt par- ticularly or altogether in the veins. This disorder, and its consequences, most frequently happen in parts of the body where the motion of the blood in the veins is most slow. Hence in advanced age the 127 flowing of blood occurs oftenest from the hsemor- rhoidal veins; for the blood in them which is greatly retarded, does not in fact return to the heart, but passes through the vena portarum, and flows through the liver. Besides, the haemorrhoidal veins have but little assistance from muscular motion, and want valves altogether. Hence follow frequent and great congestion, and not seldom, tumours or varices of the veins, and ruptures and effusions of blood. From similar causes congestion and effusion of blood often happen in the brain at the same age, and paralysis and apoplexy (which Hoffman calls hasmorrhage of the brain) are produced. From all these circumstances we may certainly, if r be not mistaken, conclude that a plethorick state of the whole system and an excessive determination and congestion of blood in the lungs, is the cause of haemoptysis. Yet it is often observed, that neither haemoptysis nor other haemorrhages, nor any other inconveniences arise from that plethorick state which succeeds the cessation of growth in the body; nor from the excessive thickness of the veins and laxity of the arteries, provided the constitution shall have been sound and vigorous: unless some powerful ex- 128 citing cause concurs at the same time. For most men and other animals are free from these inconve- niences. But when a morbid disposition has already- existed in the system, especially weakness of the lungs, either derived from parents, or generated by a malformation of the chest, or arising from other more obscure causes: haemoptysis is frequently pro- duced. And although no bad conformation may exist, particularly in the lungs, if only the habit of the whole system be weak, if a plethorick state should supervene, or if some sudden and violent external cause greatly disturbs the distribution of the blood, the bad consequences arising thence, are felt for the most part in the lungs. Experience evidently shows, that from haemoptysis accompanied by such a deter- mination and congestion of blood in the lungs, that viscus receives such an injury, that an incurable ulcer and consumption arise from it, although a simple wound would never be able to induce such bad consequences. I can by no means accurately explain what changes are produced from a congestion of blood in the lungs, and why an incurable ulcer or wound should occur during the existence of such a state of this viscus. We 1S6 understand indeed that such a state of the lungs is far from being heahhy and natural; and if it be ne- cessary for curing a wound or an ulcer, that the con- stitution of the whole body or any part of it, should be healthy and strong, it is no wonder in this case, when the lungs were already somewhat dis- eased, that a wound in them would be difficult to heal. Perhaps an excessive fulness of blood, and weakness of the vessels and of other solid parts, im- pede the absorption of effused blood, or a healthy suppuration of an ulcer. Whenever the pathology of this viscus shall be better understood, we may be able to explain this circumstance more accurately. In Jthe mean time, in my opinion, it is fair to attribute consurnption succeeding hsemoptysis, to a praeter- natural determination of blood to the lungs. For this not only gives evidence of incipient phthisis, but ac- companies the disease through almost its whole course, to its last stages, and in proportion to the greater or less force of this determination, the complaint is aug- mented or relieved. Thus all remedies which are agreed to be useful in preventing, mitigating or curing consumption, manifestly tend to diminish the abun- dance of blood, moderate its force, remove the conges- tion, and promote an equal distribution. There is no R 130 occasion to say much to show how my opinion is confirmed; it naturally arises from the theory of haemorrhages, and especially of haemoptysis. Who does not know that hght diet, consisting of milk and fruits, and frequent blood-letting, are of great ser- vice? The summer season, warm clothing, flannel shirts, frequent and moderate exercise, riding on horseback, gestation in a carriage, and sailing, — only do good by diminishing the congestion of blood in the lungs, and promoting a determination to other, especially to external parts. We have already said enough with regard to the effect of the different seasons of the year in scrofulous consumption: the same thing happens in phthisis arising from haemoptysis. There are some persons who in the spring of every year, have all the signs of congestion of blood in the lungs and inci- cipient phthisis; an abscess is formed in the lungs, it bursts, and pus is expectorated. On the approach of summer however, the complaint ceases, and the pa- tients enjoy the appearance of health. But on the re- turn of winter, the disease recurs again and again. In this way life is sometimes protracted for twenty years and more. 131 Although summer is very favourable to the con- sumptive, yet winter is by no means the most dan- gerous season. All agree that spring and autumn are much the most injurious to them; because, in those seasons the distribution of the blood is most dis- turbed, by the great and sudden changes of the weather. The perspiration is copious in the sum- mer from the heat of the air, and a due distribution to the surface of the body is promoted: the determi- nation however to the kidnies, and the quantity of urine, is diminished. But in the winter time, the ex- ternal cold checks perspiration, and drives the blood from the surface; and then the quantity of urine is much greater. There is a kind of equilibrium there- fore, between the skin and the kidnies, so that when the excretion by one is checked, it is augmented by the other. Hence many inconveniences arising from the heat of summer, and especially from the cold of winter, are happily avoided. But in the spring and in autumn that equilibrium is vascillating; hence if an excessive determination to the lungs or any other part shall already have occurred at those times, es- pecially by the action of the exciting cause, which the sudden changes of the weather afford, it ought to be greatly augmented. When however a fixed deter- 132 raination of blood takes place, either to the surface of the body, or to the kidnies, the irregular determina- tion to the lungs is lessened: and theri fore the con- sumptive feel much less inconvenience from the dis- ease in summer and in winter, when these determi- nations are regular and constant. Indeed, instances have frequently occurred which plainly show of how much consequence it is, for preventing, or curing, or alleviating this disease, that the determination of blood should be averted from the lungs. All physi- cians know that while women are pregnant they rarely die of consumption of the lungs. Nay, if a woman already decaying in a consumption becomes pregnant, the progress of the disease is generally ar- rested, or at least greatly retarded, until she brings forth her child. Yet often in a short time after par- turition, sometimes in a few weeks, sometimes in a few days only, they die of consumption. All these facts, if 1 am not deceived, are to be attributed for the most part to the diflferent distribution of the blood. During gestation, a great quantity of blood flows to the uterus, for the nourishment and forma- tion of the foetus. Hence its determination to the lungs is averted; the congestion in them is lessened or removed, and all the evils arising from it, greatly mitigated, or altogether cured But in a short time after parturition, that natural and healthy determina- tion to the uterus, ceases. It is not surprising, there- fore, that the congestion of blood should afterwards be incrtastd in the lungs, and that the disease arising from it, should grow worse. We might indeed be- lieve a priori^ that those unfortunate women had but one hope left, which nature spontaneously ex- tended for their relief. If that great determination to the uterus should suddenly cease, and no other natural one was to succeed, it is evident that the disease in the lungs would be greatly augmented, and that the greatest danger must arise thence. But it is known, that in a short time, generally a few hours only after parturition, a great determination naturally takes place to the breasts. It is reasonable enough then to expect, that this new determination would have the happiest effects, provided it should be promoted in the way nature intended, that is, by the woman suckling her child: for the congestion in the lungs ought to be diminished or altogether taken away, and life be protracted until the disease be cured by the powers of nature. And in fact, I have obtained from the highest authority some examples, and have seen one myself, in which this experiment was made, 134 and consumption of the lungs was most evidently cured altogether, without the use of any other reme- dies whatever. And I do not doubt but that this re- medy might cure many piidiisical persons, especially if the disease has not arrived at its last stages. But the experiment is rarely tried, for there are few who would believe that a woman already consumptive and nearly dying, could give milk to an infant without danger to herself and the child. Yet experience teaches that such women bear children and nourish them, not only without injury or danger, but with the greatest benefit. The children also, at least in the generality of cases, are never weak nor sickly, nor are they ob- served to experience any inconvenience from the disease under which their mothers laboured. I can hardly believe, therefore, if women suckle their own children, that any danger would arise from it, either to the child or parent; and I am clearly of opinion that it might have the happiest effects; it is better surely in so dangerous a disease, to try an un- certain remedy, than leave the patient to certain death. — But to return to the subject. Although the determination to the kidnies is greater in winter than in summer; yet it is never 135 constant: for it is often disturbed by the sudden changes of the weather, which generally occur in winter very frequently. But if the winter's cold be ever so continued, the distribution of the blood would be daily disturbed, unless the air of the chamber and the external air should be of the same temperature. When the external air is excessively cold, the air of a room is equal to or greater than summer heat; hence arise great and sudden changes of the distribution of the blood. The reason then is clear why the summer is more salubrious to the consumptive than winter: for the determination to the surface of the body which occurs in summer, is almost continual; and although the perspiration should be at one time more and ano- ther less, the determination of blood, unless from some sudden and violent cause which rarely hap- pens, is wholly changed. The same reason may be given for the effects of seatons, of issues, and of blisters, which not unfrequently give relief to the consumptive. There remains therefore, one method by which we can always hope to remove the congestion of blood in the lungs; namely, by promoting a determination to the surface of the body. Yet this, as we have often 1^6 already observed, is most effectually and most certain- ly performed, by a moderate, uniform, and constant warm air. But our climate possesses such an air only for a few months. A milder climate should therefore be sought by the consumptive: and daily experience confirms sufficiently the propriety of this advice; for many of our inhabitants are annually snatched from death, which under other circumstances would ine- vitably happen. Warm clothing and moderate exer- cise, are somewhat similar to this remedy; and what- ever good is derived from them is, in my opinion, to be attributed entirely to a change in the distri!)ution of blood. With regard to clothing, there are a few things to be observed. It is well known that flannel shirts are exceedingly beneficial in this disease. This is surely a most simple remedy, and certainly there is nothing more plain than that it will directly promote the determination of blood to the surface of the body. Linen shirts, when there is a profuse per- spiration, soon become wet and feel cold; hence perspiration is checked. But flannel shirts easily ab- sorb sweat or moisture, and do not become wet with- out there is a prodigious perspiration: hence the skin remains dry and warm, and the perspiration is greatly promoted. It is known to every one, that exercise 137 has a similar effect; it plainly appears therefore, how it could diminish or remove a congestion in the lungs. Indeed at first blush it would not be unreaspnable to apprehend dangerous consequences from exercise, by reason of the effect it has in increasing the impetus of blood. If the exercise should be violent, it would with- out doubt prove very injurious; for walking, riding, and similar more powerful exercises, immediately in- crease the difficulty of respiration, and other symp- toms. But experience has very clearly proved > that moderate exercise, sailing, gestation in a carriage, and not unfi-equently riding on horseback, — diminish or remove the congestion of blood in the lungs, and other injuries arising from it. This is evidently to be attri- buted to the increased determination of blood to the surface of the body. The celebrated CuUen, has men- tioned in his lectures a singular case, which satisfac- torily confirms this theory. It was that of a man who laboured under haemoptysis, who, while he remained at home, and used no exercise, was affected very badly, and suffered many returns of the complaint. Yet fi-om riding on horseback he always derived re- lief; and sometimes, when the disease greatly troubled him, he mounted his horse and rode for some time, with the effect of being freed from the complaint, for S 138 a time at least. Gilchrist relates other examples of a like nature, from the effect of sailing. But Sydenham extols this remedy more than all other physicians; and not only in the slight and incipient form of phthisis, but even in the last stages of the complaint, when that species of diarrhoea with night sweats termed colliquative, has already come on, and which is generally soon followed by death: " However fatal consumption may be, (says this writer,) yet I firmly maintain, that neither mercury in the venereal dist^ase, nor Peruvian bark in intermittent fever, arc more efficacious, than the exercise already com* mended, (that is, riding on horseback,) is in curing consumption; provided the patient takes care to have his sheets or bed clothes properly dried, and also, that he protracts his ride to a long journey. This I have learned from numerous experiments in which it scarcely ever failed. And although riding on horse- back is peculiarly suitable for consumption, yet journies performed in a carriage, when they have been judiciously taken, have had the happiest effects."" 31 Bishop Burnet says, that the lawyers of his time were (caeteris paribus) longer-lived than other people; and attributes 139 Later physicians do not bestow such praises upon this exercise; yet ail agree that it is often of the greatest use. It is evident therefore, how much ben^:fit consumptive patients, labouring under hered'tiry hsemoptysis, might derive from the exercise itself of travelling. The third, and indeed the most frequent cause of consumption, yet remains to be noticed: namely, ca- tarrh. Every one knows that consumption of the lungs not unfrequently succeeds a protracted catarrh: but it is often difficult to distinguish catarrh from genuine incipient consumption produced by tubercles in the lungs: for the principal symptom, that is the cough, occurs in both; and I do not doubt but that many consumptions attributed to catarrh derive their ori- gin from tubercles. But it is clear enough that catarrh not unfrequently induces true consumption, when no tubercles had previously existed in the lungs. For there are many instances where, after the most evident this to their riding the circuits on horseback: but this is un- doubtedly too violent an exprtion, except in the first stages of phthisis. There are few physicians of the present day, I be- lieve, who would recommend their patients to try this jolting remedy, in any other period of the complaint. 140 symptoms of catarrh arising from common causes, (that is, cold some how applied to the body,) a ge- nuine and fatal consumption of the lungs followed; although there were no previous signs of tubercles, or any disease in the lungs, and where there was no suspicion that a scrofulous disposition existed in the system. Sometimes also, and not seldom, consump- tion of the lungs arises from whooping cough. Since therefore, there is not the least doubt of the fact, that long continued catarrh produces consump- tion, the rationale may now be given; and if I mis- take not, the same which we have above advanced respecting haemoptysis, may be easily applied to consumption arising from catarrh. If congestion of blood in the lungs renders them liable to consump- tion, we may easily understand how a frequent and violent cough might excite that injury: for it is evi- dent that a cough of this kind impedes the motion of the blood and produces a great turgescence. Perhaps the mucous nriembrane (which is particularly affected in catarrh) may receive some injury from the disease, which might induce the mischievous consequences. But what that affection is, (if any in fact there be,) I shall not undertake to explain. If the lungs therefore 141 are weak or diseased, if a defective and contracted structure of the chest exists, or if any taint lurks in the constitution: it is no wonder that a protracted catarrh should produce consumption at that age, in which the greatest determination of blood to the lungs occurs. When consumption is produced by catarrh, all the symptoms of turgescence of blood in the lungs come on, and sometimes haemoptysis takes place. The history and progress of the disease is nearly the * same, whether it arises from haemoptysis or catarrh; the same things afford relief and do injury, and the mode of cure is the same. There is not, therefore, the least necessity to repeat in this place what has already been said. If congestion in the lungs be the source and cause of this complaint, that should with- out doubt be removed in the first place. And this effect is best achieved by means of the remedies be- fore enumerated, and especially by a change of climate. Of these three most frequent causes of consump- tion, (or rather two; for haemoptysis and catarrh might be considered as one,) we have treated sepa« 142 ratdy, as if the disease might arise from one or the other only- But it is evident enough that all those causes may concur or be conjoined in the same pa- tient. Catarrh often induces haemoptysis: perhaps also it weakens the lungs, and renders them liable to scrofulous tubercles. Blood effused from haemoptysis, and not absorbed, might form tubercles, which in pro- gress of time, might induce inflammation and suppu- ration. And from compression of the blood-vessels by scrofulous tubercles, effusion of blood, either by tran- sudation or from ruptured vessels might be produced, be followed by haemoptysis, and cause a frequent and troublesome cough. What has been particularly and separately said of these two causes, * may easily be applied to all conjoined. From all these facts and arguments, it may be concluded, if I be not mis- taken, that a change of climate would be of the greatest importance in preventing and curing con- sumption of the lungs.^^ 22 It seems then agreed, that a change of climate exerts powerful and beneficial effects upon phthisis pulmonalis, whe- ther it arises from hereditary predisposition, concealed scro- fula, haemoptysis or catarrh, and the suppurative terminations of pneumonia. But it seems not to be so unanimously con- ceded, that this change of climate is always to be made by 143 It is now our intention to treat of certain diseases which occur in more advanced age, and which arise, means of a sea voyage, in preference to a journey by land. The opinions on the usefulness, nay curative effects of sailing in this disastrous complaint, are various and diametrically oppo- site. The late professor Rush was wont to teach the inefficacy of this species of exercise, unconnected with other things, in consumption, from his chair; and the following are his senti- ments as delivered in one of his publications: " sea voyages have cured consumption, but it has only been when they have been so long, or so frequent, as to substitute the long con- tinued gentle to the violent degrees of exercise, of a shorter duration, or where they have been accompanied by some de- gree of the labour and care of navigating the ship."* On the other hand Dr. Gilchrist, who wrote particularly on the me- dical use of sea voyages, extols them in the highest terms, as a remedy for phthisis; and relates many cases to prove the justice of his encomiums. He asserts that in some instances a voyage of a few hours has accomplished the most marvel- ous change in the disease for the better. Dr. Rush, in speaking of a change of climate as a cure for consumption, says, " I do not recollect an instance of its having succeeded, except when it has been accompanied by exercise, as in travelling, or by some active laborious pursuit;**! and with respect to travelling * Inquiries, vol. ii. p. 64, on Pulmonarj' Consumption, t Ibid. 144 at least in part, from the effects of our climate, and might be cured or relieved by a change of air* by land, he has the following remarks: " journies have often performed cures in the consumption, but it has been chiefly when they have been long, and accompanied by difficulties which have roused and invigorated the powers of the mind and body."* Cullen believes it probable that some benefit would be derived from the great purity and more equal temperature of sea air than that of land, in consumption. Dr. Gourlay of Madeira says, that the itinerant consumptive patients who visit that island for their health, seldom re- cover; but attributes this to the backwardness which people feel to repair thither, until the disease has gained such an as- cendancy, that neither change of climate nor any other remedy could have any good effect. I believe there are few points in medicine that have undergone more disputation and admitted more contrariety of reasoning and opinion, than the curableness of pulmonary consumption, and the efficacy of a change of climate, travelling, and sea voyages. It is, certainly, not for me to presume at an attempt even to reconcile the jarring testimonies of venerable and eminent authorities. But as I have in a preceding note, when speaking of the general efficacy of sailing at sea, in the treatment and cure of diseases, asserted that I had seen decided advantages resulting from Inquiries, voT.ii. p. 64, on Pulmonary Consumption. 145 These fall particularly on the abdominal viscera, especially the stomach and intestines, and greatly it, I will now mention one or two cases of pulmonary con- sumption which I then had in view. Previously to doing this however, it may not be irrelevant to remark, in favour of the sea life upon consumptive people, some facts, which prove that the disease is rarely incident to ^hat life. Dr. Lind* says, "that out of 5741 sailors, who were admitted into the Naval Hospital at Haslar, near Portsmouth, in two years, only 360 of them had consumptions; and in one fourth of these," he continues, " it was brought on by bruises or falls." Hence it may be concluded, that the exercise of sailing invigorates the lungs, and fortifies them against accidents. In addition to this fact, I may state that out of 1045 patients who came under my care from the 1st of June 1809 to the first of June 1811, from among four hundred men exposed to a va- riety of climates in different parts of the United States, in the bay of Biscay, the British Channel, the Atlantic ocean, and in different sea-port towns,— there were only mjc cases of pulmonary consumption. These six, exclusive of four other cases of phthisis, received from a French hospital. The record book from which 1 take this account, exhibits a multi- farious variety of diseases; among them many cases of pleu- risy, and nearly three hundred of catarrh, which so frequently causes consumption. It appears then from this fact, that the ' " * ' ' II I I. ■ I i»i* * Essay on the means of preserving the Health of Seamen. T 14a obstruct their functions. Hence they are not only experienced in those parts, but affect the whole disease of phthisis pulmonalis is not only a rare complaint at sea, but that the acute diseases which so frequently terminate in or produce it on shore, have not the same fatal tendency when they occur under the influence of the sea air. Of the four cases I have just alluded to, I may remark, that two out of the four died in a few weeks after they were re- ceived on board from the hospital. The other two recovered. These patients were evidently in a deep consumption of the lungs. Every symptom that characterizes this complaint, was evident in each of ihem. The passage across the channel considerably relieved them, and in the course, one of four and the other of six weeks of the voyage, both entirely recovered. The recovery of these patients was as unexpected to me as it was to themselves; and I believe their only hope in coming on board was, that they might survive long enough to reach their native shores^ and die with their friends. f Since writing the note containing a quotation from Dr. Gor- don's letter respecting the climate of Madeira, the work of Dr. Gourlay has fallen into my hands. This writer men- tions,* the disease of phthisis pulmonalis as an endemick of * Observations on the Natural History, Climate, and Diseases of Madeira, daring a period of eighteen years, by Wm. Gourlay, M. D. London, 1811, • 147 system, and often produce many serious, and indeed most obstinate disorders. But we shall here only . that island. He says its fatality is prodigious among the inha- bitants. He reprobates the practice of sending consumptive patients to the island, so far advanced in the disease that their death, which is inevitable, can only be protracted for some time. He thinks the summer in that climate too hot for con- sumptive persons. " Under all circumstances," says Dr. Gour- lay,* *'in Madeira, the fittest season for invalids, is from November to the beginning of June. This was the opinion of the late Dr. Cullen, who, in his lectures on this disease, was wont to observe, in directing a change of climate, that it was as pernicious for phthisical patients to pass the summer in a very warm climate, such as Madeira, as to remain in England in winter; and indeed that the most benign climate in such cases, was found in the south of England, and in the winter of southern latitudes." From the assertion of Dr. Gourlay re- specting the fatality of consumption in Madeira, and the ex? treme frequency of the disease among the inhabitants who have never been out of the island, I think it is evident, that the climate must contain some vice that is inimical to the con- sumptive. How that place received the high character it has obtained among physicians, and among consumptive patients, I know not: certain it is, that it is wholly unmerited. Since * Observations on the Natural History, &c. of Madeira, by Dr. Gourlay^ p. 93. 148 treat of two complaints of this nature: viz., of hypo- chondriasis and gout. Since the above went to press, the " Introductory Dis- course"* of Mr. De Witt Clinton, of New York, has fallen into my hands. From it I shall make the following interesting ab- stract, and I will venture to do so, without any other apology than to say the matter is very pertinent to the subject of this work, and is already so condensed into a few well-written pa- ragraphs that I could not give the substance of the remarks, without detailing them in the words of the author. " The comparative mortality of London has not only greatly diminished within the last fifty or sixty years, but a number of diseases which, previous to that period, were very destruc- tive, have almost entirely disappeared; for instance, the plague, the rickets and the scurvy: while others that were formerly considered very mortal, are now viewed as no longer formida- ble; such as the small pox, the dysentery and intermittent fevers. « Other diseases, supposed to be less dependent on the phy- sical than on the moral and political changes which Great Britain has undergone, have increased in number and fatality; and are attributed, chiefly, to the increase of manufactures; * Delivered before the Literary and Philosophical Society of the State of New York, on the 4th of May, 18U. 14^ and, consequently, of the number of sedentary and otherwise unwholesome occupations; to the augmentation of the national wealth, and with it, of luxury and high feeding; and to the fluctuations in the conditions of life, attendant on the spirit of commercial speculation. To the first of these sources is as- cribed, in part, the regular increase of the consumption, dur- ing the last century; to the second, the more inconsiderable, but scarcely less regular, increase of apoplexy, palsy, gout) and sudden deaths; and to the last, the more frequent occur- rence of insanity in its different forms: and the increase of in- temperance and vice, in a large and populous city, doubt- less contributes much to the augmentation of all these dis- eases. " Dr. Heberden states the proportion of these three classes of disease, at the beginning, middle, and end, of the eighteenth century, to have been as follows: Beginning. Consumption, 3,000 Palsy, apoplexy, &c, 157 Lunatic, " 27 « If we compare the mortality from consumption, at those three periods, with the total mortality, we find, that in 1669 the deaths, from consumption, were, to the whole, as 1 to about 6 2 In 1749, 1 5 5 1799, I 3 8 1808, 1 3 6 "The Middle. End. 4,000 5,000 280 300 75 70 150 " The reports of consumption, in other parts of Great Britain, correspond, in a great degree, with the accounts of its preva- lence ill London, and, therefore, render this ascription of its causes and origin unbatisfactory. " Dr. Lettsom, however, in a letter to Dr. Hosack, on the diseases of London, (yifner. Med. and Phil. Reg. vol. 2.) says, *' Whilst the phthisis p\jlmonalis is rapidly increasing in America, and in the European continent, it is diminishiiig here. The croup is less fatal, in consequence of the imme- diate and free use of the lancet, and of leeches, with pur- gatives, than heretofore; nor is angina scarlatina either so frequent or so fatal. The typhus is almost extinct, and the cho- lera morbus is unfrequent; and, as far as my experience ex- tends, the syphilis is milder or easier cured; and, lately, such has been the prolongation of health and life as to lessen the premiums of insurance considerably." "Out of 19,954 deaths, in London, in 1808, 5,220 are as- cribed to the consumption. The christenings, in that year, were 19,906, nearly equal to the burials. " In 1809, the healthiest year which London ever enjoyed, there were 16,680 deaths, 4,570 of which were produced by the consumption; the number of christenings was 19,612, making the excess of births above tTie deaths nearly 3,000. (See the London Annual Medical Review and Register, for 1808 and 1809») " Dr. James 151 *< Dr. James E. Smith says, that " in Italy, consumptions are found to be very contagious, thoiijjh less evidently so in England." It is intimated, if my memory serves me, in that excellent work, the Emporium, that the general use of cotton shirts, 8cc. may have a pernicious influence in producin* the disease. Its increased fatality in Europe, as well as in America, is, probably, owing to a complication of causes; and, indeed, the periodical prevalence and disappearance of certain dis- eases, must be classed among those aixana which providence has concealed from man. «' Salubrious as the climate of Madeira is generally reck- oned, we find, that even there pulmonary diseases cut ofF a great number of the inhabitants. Of the various districts of North America, New York has been considered, by many, as being especially favoured with regard to the mildness of its seasons; and the changes of its weather were referred chiefly to the diff*erence in the prevailing winds. Among a series of interestng remarks on the climate and diseases of New York, made by Lieutenant-governor Golden, about seventy years ago, and inserted in the American Medical and Philo- sophical Register, vol. I., this medical philosopher observes, " The air of the country being almost always clear, and its spring strong, we have few consumptions, or diseases of the lungs." " People inclined to be consumptive in England, are often perfectly cured by our fine air; but if there be ulcei's formed they die. The climate grows every day better, as the country is cleared of the woods; and more healthy, as all the people that have lived long here testify. This has even been sen- sible to me, though I have been but, about twelve years in this 15Q country; /, therefore, doubt not but it will, in time, become one of the most agreeable and healthy climates on the face of the earth. As it is at present, I prefer it to the climate of England, and, I believe, most people that have lived any considerable time here, and have returned to England, will confirm this." " If the climate of New York was formerly thus mild and healihy, and a constant amelioration in its tempera- ture is consequent upon our numerous settlements and improvements, as has been maintained by many distin- guished writers, to what shall we ascribe the extraordi- nary mortality occasioned by pulmonary consumption at the present day. None will deny this disorder to be influenced by climate, and independent of eflccts arising from particular employments, and modes of living; but we will, perhaps, find the most satisfactory answer to this question, in considering phthisis in its various forms as the off'spring rather of in- creased dissipation, of great imprudence in dress, and of con- sequent exposure to sudden changes of temperature, than of any peculiarity in our climate and seasons."* Since writing note 18, I have received a letter from Dr. Gerard Dayers, formerly surgeon's mate of the United States, when I was surgeon of that ship. It enables me to add the case of a favourable termination of a wound into the ca- * Note N. N. p. 1«0. 153 vity of the lungs, which I would have related in that note, but could not at that time assert positively the favourable nature of the result. I however will subjoin it in this place, though not immediately connected with ihe preceding matter. I was called while on shore, to see a man by the name of Tindell, then one of the United States* boat's crew. He had been wounded in three or four places by a pretty large couteau- de-c/iasse, in an affray with a Portuguese sailor. I found him lying on his left side in Dr. Balfour's shop in Norfolk, whither he had been carried by some of his companions. Upon exami- nation of his wounds, I perceived that the severest perforated the left lobe of tlie lungs. Through this wound he was bleed- ing freely, and also expectorating blood. After taking a good deal of blood from his arm, I had him removed to comfortable quarters in Water street, where I again bled him in the evening and very largely on the following morning. He was kept ex- ceedingly low for the space perhaps often days, and as I was about to sail in another ship for France, I left him with the most favourable symptoms in the careof one of my mates, who from his experience and knowledge was well able to give him every judicious and necessary assistance. I accordingly sailed the next day, and heard no more after my return, of the par- ticulars of his fate, than that he had recovered. The case ex- cited considerable interest among the physicians of Norfolk, from whom I frequently had inquiries respecting his condition; it must therefore be well known to those gentlemen, as I am sure it is to commodore Decatur, and the officers of his ship. The following is a brief account of this man's case, after I left him in the hands of Dr. Dayers, (now surgeon of the Congress,) from a late letter received from that gentleman. u 154 *• U. S. Frigate Congress, Portsmouth, N. H., March 7th, 1815. * * * * " As respects the surgieal case, I lost all my books, notes, 8cc. at the time the English made an attack on the U. S. ship Adams at Hampden in Maine, but as far as memory will assist me, I will give you the symptoms and mode of treatment " In the case of Tindell, who was wounded in the lungs by a sword, the breathing was very much obstructed, there was bloody expectorationv&c; he was bled onee after he came un- der my care: in conjunction with this important remedy, he was kept perfectly at rest, cooling laxatives were adminis- tered, and a low diet observed. Under this treatment he got perfectly well, since then I have heard nothing of him. V ** I hope you will pardon the concise account that I have given you; but what I have mentioned is strictly so, as far as my recollection serves me. The treatment previous to his coming under my particular care, I have very little know- ledge of: but I suppose you have, as you attended him for a short time. " Yours, with great esteem, « GERARD D AYERS." The instrument by which the wound just related was made, fell into my hands. It was at least one inch broad, and very thick on the back edge, at the point up to which it must have been thrust into the body. The perfect and speedy recovery of this man, is another convincing proof that violent wounds may be made into the lungs, without inducing pulmonary consumption, or any other material injury. 155 sp:ction hi. Of the causes of Hypochondria, especially its origin from the effects of climate, diet, and mode of life. Its various symptoms. Its connection with the haemorrhoidal flux and its affinity to this disease, deduced from the similarity of its causes. The general absence of any praeternatural ap- pearances in the dissection of the dead bodies of hypochon- driacks. Sometimes turgescence in the mesenterick veins observable. The different remedies for this disease. The be- neficial effects of riding on horseback, especially when conjoined with a change of climate. Hypochondria is well known to all physicians, for there is not any chronick disease scarcely, of more frequent occurrence than this, at least in the island of great Britain. Various, and indeeed innu- merable symptoms, both of mind and body, accom- pany this complaint. But especially a lassitude and torpor of the whole system, depression of spirits, fear, and anxiety, together with a derangement of the func- tions of the stomach and intestines. This diversified disease appears to originate from the effects of our climate; for it is most frequent in cold moist coun- tries; while in those that are temperate or warm, it is either very rare, or altogether unknown. It is ob- 156 served also, that the hypochondriack are much better in summer than in winter. Hence it is probable that the disease might be relieved or cured by a change of climate. Indeed it is difficult and perhaps impos- sible to assign a satisfactory and accurate reason for all the symptoms which occur in this disease. For many have a connexion with nervous affections, the nature of which is not sufficiently investigated to ena- ble us to understand the complaint. Many depend on a certain incomprehensible sympathy, which exists be- .tween the different parts of the system, and between the mind and the body. But this sympathy is veiled in the darkest obscurity. Such symptoms, therefore, I shall not attempt to explain. I shall endeavour only to investigate the sensible causes of the disease, both proximate and remote; and to show from them and from analogy of the effects of such things as do harm or good, how the complaint may be cured by a change of climate, or at least that it can be rendered milder. It can scarcely be doubted that the proximate cause of this disease exists in the alimentary canal; for the most of the symptoms by which hypochon- driacks are troubled, evidently arise from the dis- turbed functions of the stomach and intestines. Such 157 as, anorexia, nausea, vomiting, eructation, rumina- tion, cardialgia, gastrodynia, flatulency, tormina, sometimes diarrhoea, but ofteaer costiveness of the bowels. All these are to be attributed, without doubt, to debility or want of tone in th'j alimentary canal. The affections of the mind too, which consti- tute so considerable a portion of this complaint at least in most cases, are clearly produced by the same weakness of the stomach and intestines; although sometimes, the affections of the mind are observed to bring on debility of the stomach and intestines, and true hypochondria. A very difficult question now presents itself: if certain affections of the mind aris« from weakness of the intestines, how happens it, that the debility often occurs, without such mental disorders? For there are many instances where the sick are dis- tressingly troubled with all the diseases of the stomach and intestines which happen to hypochondriacks, while the mind is in no way affected. I confess my inability to^ solve this difficulty: indeed I doubt whether it can be explained until the reciprocal ac- tion of the mind and body upon each other, is more accurately investigated. It has never been properly 158 understood, how the diseases of the stomach affect the mind; it is hardly to be expected therefore that a reason can be given why this should happen only in some cases. Perhaps a peculiar disposition in the nervous system, or in the mind itself is necessary, in order that those, affections may be produced. What this disposition is, I confess I do not know. Yet it is evident that the affections of the mind often de- pend on the morbid state of the stomach and intes- tines; since it generally happens that when this dis- eased condition is removed, the mind is restored to its former healthiness. We have said that the disease, or rather the cause of the diseases of the intestines is debility, or want of tone. Many reasons confirm this opinion. Those symptoms above enumerated, evidently indicate a debility of the stomach and intestines; a weakness of the whole system accompanies the disease, and not unfrequently appears to produce it; many causes which debilitate the whole body, but especially the intestines, often bring on the disease; and whatever invigorates the intestines or the general system, is beneficial to hypochondriacks. But besides these, if I am not mistaken, another evil often exists in 159 the system, which increases the debility and want of tone in the alimentary canal, as well as the hypochon- dria, and perhaps also it might bring on the disease; namely, a tardy circulation of the blood, and also congestion in the abdomen. If a free and natural dis- tribution of blood is necessary for sustaining the health and strength of the whole system, or any of its parts, it may easily be credited that from an im- peded motion of this fluid in the abdominal viscera, the intestines would receive such an injury, that they would be rendered liable to various disorders. Or, if they should already have been debilitated and dis- eased, and the distribution of the blood disturbed, it is probable that the injury would fall especially on them. Finally, it is evident that if the circulation of the blood should languish in consequence of a want of exercise, or from other causes, although it would affect the whole system, yet the evils arising from it would be particularly felt in the abdomen; for the motion of the venous blood is naturall}' most slow there, on account of the long circuit it makes through the liver before it returns to the heart. This opinion, that hypochondria arises from a tardy circulation and also congestion of the blood in the abdomen, is by no means inconsistent with reason, 160 and we shall now see how it is confirmed by observa- tion of the remote causes of the disease, and those things which are beneficial or hurtful to the hypo- chondriack. The different causes which bring on hypo- chondria, are observed to injure directly and imme- diately, the stomach and intestines. Others again impede in the first place the motion of the fluids, and debilitate in this way perhaps, the abdominal viscera, and in our opinion cause hypochondria. Some indeed, have evidently both those effects. We have said that a cold moist climate, like that which occurs in our northern countries, especially in the winter season, produces a disposition to hypochondria. The most manifest effect of such a climate is, to check the perspiration and hinder the distribution of the fluids to the surface of the body. Hence internal congestion is to be feared. I do not intend to deny, that a cold and humid climate can directly affect the stomach and nervous system, and finally the mind itself, even if it should not disturb the motion of the fluids. It is known that moist air relaxes and weakens the mus- cular fibres of the whole body. It is not surprising therefore, that the stomach and intestines should suffer from the same effects. The inhabitants of damp 161 cold countries are languid, inactive, and inclined to melancholy; for that reason perhaps, they are liable to this disease. Nor is it unreasonable to attribute this distressing disposition of mind and body to ob* structed perspiration. For Sanctorius has declared in his established aphorisms, that cheerfulness of mind is produced during a very free perspiration by the sur- face of the body; and on the other hand, that a sense of heaviness in the body and sadness of mind is per- ceived when the perspiration is obstructed. Almost all persons, however healthy and robust they may be, and free from the hypochondriack disease, observe the most evident effects both on the mind and body, to follow different changes of the weather. When it is temperate, dry and clear, the body receives new strength and activity, and the mind increased cheer- fulness. But on the other hand, when the atmosphere is cold, humid, cloudy and dark, the body becomes weak and languid, and the mind dull and gloomy. These differences are perhaps to be attributed to the effects of climate on the nervous system; for there is no doubt but that it does exert powerful effects in this way. But if I be not mistaken, the greatest part of these differences in the feelings is to be ascribed to the disturbed distribution of the fluids; X 162 for if this is properly promoted by a due degree of exercise, neither sadness of mind nor lassitude of body is for the most part produced by the effects of a cold moist climate upon the nervous system. Another, and indeed the most frequent cause of this complaint, is an indolent and sedentary life. Most men devoted to study, or occupied with other business, which requires a continual and close ap- plication of the mind, and hardly any exercise of body, are more or less troubled with this disorder. This kind of life can do harm in two ways, and pro- duce a disposition to hypochondria: in the first place, a sluggish motion of the blood is produced by it, in consequence of a want of natural exercise: for phy- sicians know, that the action of the muscles is ne- cessary, in order to promote duly the circulation of the blood. Hence also perspiration and a determina- tion to the surface is diminished; consequently ple- thora is produced in the system; congestion in the in- ternal parts; and we have already shown that the evils arising from this source would especially affect the abdomen in this period of life. Besides, when the muscles are not properly exercised, they soon lose their former and natural strength, the moving powers 163 in a sedendary life, necessarily languish, and the whole body becomes debilitated; hence perhaps the stomach and intestines, by sympathy or consent, de- rive a similar debility or want of tone. But my opi- nion is, that hypochondria arising from a sedentary life, is rather to be attributed to an obstructed dis- tribution of the fluids to external parts, than to a weak- ness and want of tone in the muscles; though this want of tone may doubtless increase the evil. For in warm countries, where the perspiration and deter- mination to the surface is sufiiciently promoted by the heat of the air alone, hypochondria rarely occurs, although debility and want of tone are common enough, and the inhabitants do not use much ex- ercise. Certain affections of the mind which we call de- pressing passions, especially grief, and continual and distressing anxiety, often cause hypochondria. But it is well known, that all serious affections of the mind affect the stomach in some degree, and vice versa, the mind is disturbed by the different diseases of the stomach. For it has been observed, that sad- ness of mind, and other effects of this nature, not only debilitate in a surprising manner the stomach 164 and whole body, but also greatly obstruct perspi- ration. When therefore, the motion of the blood be- comes languid, and the deter mihation to the surface is in this manner diverted, and the stomach and in- testines from their consent with the mind are debili- tated by the same cause: is it not probable that congestion in the abdominal vicera will succeed that debility, and would be the cause of hypochondria fol- lowing? Many causes in fact produce this disease, by debi- litating the stomach, the intestines, and the general system, which do not appear directly or particularly to affect the distribution of the fluids. Such are large, and especially slaw evacuations, the menstrual flux, fluor albus, sometimes excessive venery: these give rise to a debility of the whole system. Other causes particularly weaken the stomach and intestines: such are the excessive use of tea, tobacco or opium, and of other narcoticks; or the frequent repetition of the more powerful emeticks and catharticks, diarrhoea or continual binding of the bowels. Other causes however, which produce hypochon- dria or at least a disposition to it, evidently appear to 165 cause a sluggish motion and congestion of blood in the abdomen. Plethora without doubt in many cases contributes not a little to produce this disease. For men who use a full and generous diet, and lead an indolent and sedentary life, are very much inclined to hypochondria, and it can hardly be doubted but that a plethorick state may exist in the system of such persons, and may create the greatest part of the dis- order; especially when we consider the remedies which give relief to such patients. For a lighter and more spare diet, or one consisting of fruits; frequent and constant exercise, and sometimes the loss of blood, — greatly relieve them; and all these evi- dently and directly diminish or remove plethora. We have before explained why plethora, if any exists in the system, particularly shows itself in the abdomen. For hypochondria only occurs in advanced age: in infancy it is altogether unknown; it is most frequently met with after the thirtieth or thirty-fifth year. The disease also not unfrequently arises from those tumours in tl^ spleen or liver, which are some- times observed after intermittents that have been imperfectly cured. Tumours of this kind evident!} 166 obstruct the free motion of the blood in the abdomen, and consequently produce congestion. It arises too, and not rarely, from a haemorrhagick disposition, when the haemorrhages haie ceased. It appears from observations that those who have had haemorrhages, are greatly inclined to this disease. Those who have had the haemorrhoidal flux checked, are particularly liable to hypochondria. And from this source hypochondria often arises. It appears evident to every one that a suppression of that flux, produces a congestion of blood in the abdomen. There is a very remarkable connexion between hy- pochondria and the hsemorrhoidal flux: the same age; the same climate and season of the year; the same mode of living; as for instance a full and gross diet, and an indolent and sedentary life, a plethorick habit, a haemorrhagick disposition, and costiveness of the bowels, — equally induce both. They occur not unfrequently in the same patient, and occasionally at the same time; and hypochondria is often produced by a suppression of the haemorrhoidal flux; when that is restored, this in its turn is released. But the haemorrhoidal flux arises without doubt from con- gestion of blood in the abdomen: from this fact there- 167 fore, another argument arises which tends to prove that at least in many cases, hypochondria derives its origin from the same source. Nothing of consequence can be learned on this subject by dissecting dead bodies; for hypochondria, however troublesome and difficult of cure it may be, and notwithstanding it distressingly torments many persons during the greatest part of life, yet it is scarcely ever fatal, unless sometimes when it brings on other diseases, as dropsy for example, or a cachec- tick state of the system. In some of the dead bodies of hypochondriacks however, a congestion of blood has been plainly observed in the mesenterick veins. There is every reason I am persuaded, to deduce two principal causes of hypochondria, viz. a debility and want of tone in the stomach and intestines, and a congestion of blood in the abdomen. The mode of curing the disease then, according to this theory, renders it necessary, before attempting any thing else, to invigorate the stomach and intestines, remove the congestion of blood from the abdomen, and promote the free motion and distribution of this fluid. To the first intention, many remedies are adapted; and often 168 not a little benefit is derived from tonick medicines, cither taken internally or otherwise applied. Of this kind are the Peruvian bark, steel, bitters, the cold bath. But these remedies rarely effect a perfect cure of the disease, unless others are at the same time exhibited, which answer the other intention of cure, namely, to restore the due motion and distribution of the fluids. Now this is best effected by exercise in the warm air, especially by riding on horseback, than which nothing gives greater relief to those labouring under hypochondria. The commendations which Sydenham has bestowed upon the exercise of riding on horseback, as a cure for consumption, might perhaps be more properly applied to the hy- pochondria. It does not only effect a due distribution of the fluids, — promote the motion of the blood to the smallest vessels of extreme parts, — afford activity to the moving powers of the system and to the whole body, — but especially benefits the stomach and the other abdominal viscera. No other kind of exercise affords such concussion, by which the circulation of the blood in the abdomen is equally promoted, and it thus seems to increase the peristaltick motion and strength of the intestines. Hence all the excretions of the fluids which are so essentially useful for the 169 digestion of food, are promoted, and the nutriment is properly and perfectly concocted. The intestines being rendered healthy in this way, the mind by its peculiar sympathy with the stomach, receives its ac- customed activity and cheerfulness. This important remedy is rendered still more effi- / cacious when conjoined to a change of climate. Wc have already said enough with regard to the effects of a moderately warm climate, in promoting the due distribution of the fluids, which we have endeavour- ed to prove, is of the greatest utility also in hypo- chondria. But since this disease affects the mind in a great degree, and often derives its origin from it, it is evident, that a temperate and pleasant climate, and indeed a change of place itself, would be ex- ceedingly useful to the sick. A finer climate than that of our own country, gayer manners, new and pleasant scenes, all occupy the mind agreeably, and delightfully divert the imagination. By these means also, when the disease has but just begun to affect the mind, the patient would experience the greatest relief by reason of the sympathy that exists be- tween the mind and the abdominal viscera. Y 170 But a change of place and the journey itself, be- sides the benefit arising from long continued exer- cise, produce other most powerful effects. A certain connexion exists between distance and time, estimat- ed by the remarkable incidents of our life, which ex- erts happy effects on the mind. Travelling (from the number of interesting occurrences that happen al- most daily) produces similar effects, and causes an oblivion of our sorrows, just as the lapse of years produces sooner or later relief to all diseased or melancholy minds. Distance from our home, also, removes every thing from our view, which might recall to the imagination the past sorrows of the mind. Those little troubles too, which arise from domestick concerns, and which often solicit too much attention from hypochondriacks, are thus far removed from their sight. Finally, that lazy disposition in which hypochon- driacks indulge at home, is necessarily banished in travelling. Inactivity and gloominess of mind con- stitute the greatest part of this disease: whatever therefore engages the attention, would, it is evi- dent, be very useful; and all exertions of the mind, 171 although forced and irksome at first, occupy its at- tcntion, and serve to introduce a new train of ideas. By these means the mind is gradually restored to its wonted cheerfulness, the intestines take on their former healthy action^^, and each reciprocally imparts its proper vigour. *3 The new and healthy change produced in the morbid $tate of the stomach and intestines, which occurs in the dis- tressing disease of hypochondria, is undoubtedly one of the most efficient and potent effects of travelling, as a remedy for this complaint. In hypochondria. Dr. Gregory has pretermit- ted any mention of a sea-voyage, and wisely indeed has he done so. I have heard of this means of changing place and scene, recommended in this complaint, than which no advice could be more irrational and disastrous. It is somewhat re- markable that an exercise so efficacious as that derived from a sea-voyage, in many other complaints, should not prove equally beneficial in all where a change of place is proper. Put it can only be attributed to the mental uneasiness I have before mentioned (note 1 5), produced by the tumultuous vexa- tions of a sea life, combined with the want of other comforts, as cleanliness of person, and changes of dress, which are the inevitable concommitants of a voyage, particularly of a long one. A change of dress may seem a matter of trivial impor- tance; but in hypochondria it is fur from being so; and I well know from actual observation that this disease^ which 172 as I shall presently say, is common on ship-board, is al- ways benefited for a time, by a change of dress. This disorder is generated by the monotony of a sea life, and generally affects landmen and those whose habitual occupations of reading or amusement on shore, are interrupted or entirely prevented, by the noisy din of a ship. I never failed to ob- serve such persons better after muster on a Sunday morning, when the regulations of the ship compelled every one on board to pass inspection, in a clean and fresh attire. But a sea-voyage, if it exceeds a day or two, must be injurious to hypochondriacks for the reasons I have mentioned. As th©; effect of travelling on the bowels, in producing a new and healthy action in them, has just been mentioned, it may here not be amiss to take notice of some of those affections of them, which are generated by particular climates, and which con- sequently we may reasonably hope to cure, by flying from the place where they received existence. In all cases of disorder of the intestines depending on an undue secretion of bile, or on a deficiency of this secretion, or an unhealthy state of il, a change of climate by means of a sea-voyage, may undoubtedly be expected to do good. " Sea- sickness, and a sea-voyage," says an able writer, " contribute very much to restore the secretion of healthy bile, so neces- sary to the welfare of the animal economy; and symptoms of dyspepsia and diminished secretion, which are now rendered more conspicuous among females from their sedentary life, are most effectually removed by the means already suggest- 173 cd.*** It is however, only in cases where these affections, as just specified, are unconnected with any mental uneasiness such as occurs in hypochondria, that any reasonable depen- dance can be placed on a sea-voyage. I am the more inclined to this opinion, because I have seen decided inconveniences, nay bad consequences, arising from the influence of a sea life on hypochondriacks; chiefly because it aggravates a prominent symptom of this disease, viz. costiveness. It is well known that the inhabitants of hot countries, are liable to many diseases which have their sole origin in the de- rangement of the functions of the liver, produced by the heat of the air. The most common of these, are the complaints generated by the increased secretion of bile, either causing a regurgitation of it to the stomach, or an excessive determina- tion of it to the firimce via. Hence obstinate dysenteries and diarrhoeas arise, which becoming, as they very frequently do, chronick — produce a state of general ill health, and a perpe- tual want of tone in the stomach and intestines. Such a situa- tion calls for a change of climate. By means of this, the su- perabundant secretion of the bile is reduced to the healthy and requisite portion, its activity on the alimentary system consequently very much lessened, and the wonted vigour of the stomach reproduced. With the healthiness of this organ, the intestines receive a simultaneous invigoration, and the evils arising from the disturbed functions of both, are speedily and effectually banished from the system. The dis- orders above enumerated, as they are engendered by a warm * Suund«r3 «n the Liver, duodec. p. 148. 174 climate, require a change to a colder region; and this change effected by means of a sea-voyage, effectually restores the constitution to health and perhaps to vigour — provided indeed the hot climate had not made such pernicious inroads on the system, as to leave the liver and abdominal vicera in a radi- cally unsound condition. The practice of seeking relief for violent affections of the vicera of the abdomen, produced by the vices of particular climes, is of very old date; hence we are told that the ancient Carribean Indians, who were subject to palsy in consequence of the violent convulsive cholicks common to all the natives of the torrid zone, had themselves conveyed to countries colder than their own, when they could not resort to the hot baths in the northern parts of Jamaica; and this change of climate was always followed by the most beneficial effects.* The present professor of the practice of physick in this university, says in his lectures, that he has known diarrhoeas of the West Indies cured by the patient^s coming to the United States. Besides the use of a change of climate in the disorders of the bowels, produced by an intensely warm climate: we may safely recommend such change in the obstinate affections to which they are liable in our own country. On the authority of the professor just mentioned, I may state, that obstinate chronick diarrhoeas contracted in the United States, have been perfectly cured by a voyage to the West Indies. In * Neale on Consumption, p. 205, 175 In cholera infantum we know it to be the common practice of physicians, to send the little patients into the country, and this is not unfrequently done, with scarcely a ray of hope either in the minds of the parent or physician, that a recovery will be the consequence; and yet a few weeks, and not unfre- quently « few days only, have been known to snatch the pa- tient from the jaws of death as it were. In this disease the sea-air seems peculiarly favourable. In proof of this, profes- sor Barton says that it is a very common and mortal com- plaint, in the town of Dover, in Delaware; while in the town of Lewis in the same state, but on the very borders of it, and exposed to the constant influence of sea-air, — it is altogether unknown. AH these facts prove, that a change of climate is highly beneficial in the disorders of the bowels; to which I may add that I have seen unequivocal advantages arising from a sea voyage, in all the chronick affections of the intestines to which seamen are so liable from the frequent changes in their diet. 176 SECTION IV, Of Gout. — Of the effects of a cold and humid climate on arthritick constitutions, and the general inefficacy of the remedies used in this disease. — The advantage of a change of climate over all other remedies in this complaint, parti- cularly from a cold to a warm one, deduced from the effects of travelling and warm air, in promoting a free and healthy determination of the fluids to the skin, especially in old persons. — Also the beneficial effects of a mild climate on the disorders of the stomach, so intimately connected and al- most always combined with gout. — Arguments in favour of a change of climate in gout, inferred from a consideration of the remote causes of the disease.— Of its effects in avert- ing the ill consequences of repressed gout, which generally succeed the use of other remedies. A FEW observations will be made on the subject of gout, not only because we are of opinion that this disease is to be ascribed to the effects of climate, nor because we expect that a change of climate alone, without the use of other remedies, will perform a perfect cure: but, on account of the variety of rea- sons which incline us to the opinion, that our cold, humid and variable climate is extremely hurtful to gouty persons, and, on the contrary, that warmer 177 countries would often be of the greatest service to them. All physicians confess that but a small num- ber of remedies are truly useful in this disease; scarcely any that can radically extirpate it, and few that can assuage the agony of its miserable victims. Of those too, which hold forth the prospect of re- lieving pain or curing the disease, some become so unpleasant to the patients, that they are soon rejected. Few men are endowed with sufficient fortitude to be willing to persist for any length of time, in the use of disagreeable medicines, especially if they be not administered during the actual existence of the vio- lent paroxysms, but only given during the intervals of the disease, when the patient experiences neither inconveniences, nor pains, nor sickness. All physi- cians agree, that frequent and powerful exercise and slender diet, are the only remedies by which the cure of gout can be safely looked for. But the sick universally reprobate remedies of this nature; nor can they so far overcome the force of habit, as to consent to be cured of their disorder on such condi- tions. But the disease evidently deprives many per- sons of the use of the limbs, so that exercise is ren- dered impossible; while others, on account of their debilitated state, or from other causes, absolutely Z 178 stand in need of a generous diet. A pleasant, effica- cious and safe remedy for this disease, is therefore an important desideratum; and I entertain the greatest hopes that a warm climate is gifted with these ad- vantages. There are some remedies indeed which mitigate, for a short time, the excruciating pains of gout, and others which seem to drive the disease from the whole system; but they are often observed to bring upon the wretched patients, new and more distressing disorders, or even death itself. Of this kind are the various remedies applied to the pained parts, especially discutients, or cold, or such as are composed of spirit of wine and the like; certain me- dicines also, taken into the stomach, and particularly aromaticks and bitters, such as compose the Portland powder. Since therefore, gout not unfrequently acts in some way as a remedy for other and more afflict- ing diseases, it surely ought not to be cured, with- out we could at the same time prevent the evils which usually arise from repressed gout: and this too is best effected by a change of climate. It is not my intention to treat fully and particu- larly of gout: it will be sufficient to show the useful- ness of a change of climate, by noticing some of the 17^ remote causes of the disease, and from our experi- ence of those things which are beneficial or hurtful. I am not able to draw any conclusion of this nature from the proximate cause of the disorder, since it is so very obscure. Some of the remote causes indeed, are scarcely better understood, and particularly the predisposition, strictly called, or the germ of the dis- ease. Something of this kind exists we well know; for the most of the remote causes, either predispos- ing or occasional, produce gout only in some persons, while in others they have not the effect of generating any disease at all, or one of an entirely different na- ture. But the nature of that predisposition or the seeds of the disease which are transmitted from pa- rents to their offspring, remains as yet in obscurity. We must seek in other sources of reasoning then, further exposition. The other predisposing causes are, particularly, advanced age, too full a habit of body, with corpulency, plethora, rich living, drunk- enness, premature and immoderate venery, and above all, an indolent and sedentary life. With respect to the occasional or exciting causes, there is no occa- sion to say much. I can hardly believe that gout is ever produced by any sudden or violent cause, un- less a strong disposition to it had previously existed 180 in the system; and, when that disposition does exists the disease generally recurs periodically without any evident exciting cause. Sometimes indeed a pa- roxysm is brought on by powerful affections of the mind, (though not unfrequently it is banished by the same); sometimes the infliction of external violence, particularly on the lower limbs, a sprain, or fatigue; occasionally, an omission of an accustomed exercise, or a suppression of a customary evacuation; often im- proper food, gluttony, a surfeit, and whatever pro- duces indigestion and acidity in the stomach. For it is well known that affections of this kind, are almost always the precursors of a paroxysm of gout. But besides this, the exciting causes, and perhaps also the predisposing, often arise from the state of the air. Regular gout, which, when it has begun, generally recurs about the same time of the year: afflicts the patient first in the spring; for the most part in the end of January or beginning of February; never in summer time, unless from some sudden and violent exciting cause. After the disease has ad- vanced, when the patient suflTcrs two paroxysms dur- ing the year, one happens in the spring and the other in the autumn: but in summer the patient is entirely 181 exempt from the complaint. Finally, in those cases when the patient is so very severely afflicted, as to lose the use of his limbs, and is confined to bed for a considerable portion of the year, he derives the greatest relief from the summer season. Those ex- cruciating pains which medicine can scarcely touch, are always greatly relieved by the provision of nature, and generally cease altogether during these three or four months of the year. Reasoning from this fact, a change of climate promises the highest advantages in this disease. Cold air is doubtless injurious to gouty persons; for they carefully cover the parts particularly affected with the disease, and derive some relief from this practice. The most judicious physicians indeed do not permit any other remedy to be applied to the pained limb, than woollen cloth, or something of a similar kind. It is agreed too that sudden applica- tion of cold to the body, not unfrequently brings on a gouty paroxysm. And gouty persons frequently feel slight arthritick pains when any degree of cold is applied to the feet. Physicians well know also, that a checking of the customary sweat or perspira- tion of the feet, is often the forerunner of a gouty pa- 182 roxysm. Slight paroxysms too, which produce seve. rer ones, are dissipated by gentle bathing of the feet or sometimes of the whole body. Hence therefore, it is very probable that suppressed perspiration is injurious to the gouty patients, while a free discharge by the skin is beneficial. In spring and in autumn when the weather is very variable, the disease is greatly aggravatedi and in summer, as we have be- fore remarked, it ceases. To avoid therefore the re- mote causes, either predisposing or occasional, aris- ing from the air, a change of climate is strenuously to be recommended. We shall now notice in what way a favourable climate promises to overcome the other remote causes. Disorders of the stomach almost always precede a paroxysm of gout, and indeed afflict most gouty persons, and constitute a great part of the disease. When speaking of hypochondria we remarked that warm climates are not much disposed to produce these diseases, and indeed with us they occur rarely in the summer season. To whatever causes therefore that relief of the diseases of the stomach which arises from a mild atmosphere, is to be ascribed; whether to its direct action on the nervous system or to its 183 effects in promoting and distributing the fluids — it is evident that a change of climate is of the greatest advantage in those affections — and as they are cured or relieved, it is reasonable to expect, that gout would derive infinite benefit from the same sources. Gout, as we have before observed, generally at- tacks those who have passed the prime of life, that is, who have reached the thirtieth or thirty- fifth year of age. In infancy it is almost altogether unknown, and in boyhood is exceedingly rare: But in more ad- vanced age the perspiration is sensibly diminished; for many minute vessels and cutaneous pores, are contracted in process of time, and coalesce. Old men generally neglect to take their accustomed and necessary exercise, for the pristine activity of miriU and body are then wanting; and they are often engag- ed in sedentary employments. In such men therefore, travelling into warm countries, if I am not mistaken, would prove very successful, and restore the distri- bution to the surface and the excretion by the skin, and perhaps might in this way relieve this disease. Gout generally attacks those who indulge in high living, and are given to the excessive Ose of wine 184 and other spiritous liquors. To these therefore, above all other men, we believe that the freest per- spiration by the skin is necessary; for a certain equi- librium between what is taken in and passed out of the system, is required for health. Now this balance is evidently disturbed, if any one uses too full a diet, and leads an indolent and sedentary life. Experience satisfactorily shows, that various diseases are pro- duced by this cause, and especially gout. Men who use a temperate and light diet, although they may lead an inactive life, are rarely attacked by gout: and those who use powerful and frequent exercise, espe- cially those who get an appetite by hard and con- tinual labour, although they daily consume a great quantity of gross food, nay, and indulge in spiritous liquors — are rarely troubled with this complaint. There are some examples even, of men having suf- fered hereditary gout (which is generally esteemed the worst, and the most difficult of cure) for many years, being reduced to poverty, and obliged to seek a livelihood by hard labour — have been entirely cured. Examples of this kind very clearly show of how much importance it is for relieving or curing this disease, that the freest determination of the fluids to the surface of the body should be promoted. I 185 am by no means ignorant, that another and altogether different reason might be given on this subject, and attributed to the benefit received by exercise and its effects on the solid parts. Exercise without doubt not only promotes a free distribution of the fluids, but also procures strength and vigour to the mus- cles and the general constitution, preserves and in- creases it. I will not contend that exercise would not in this way be beneficial to ttie gouty, especially to those already broken and debilitated by the dis- ease. But there are arguments arising from the history of the disease, and from analogy of those things that are useful, which show that the benefit derived from exercise is to be attributed at least in a great mea- sure, to its effects in promoting a due distribution of the fluids. From what has been said above, if I be not mistaken, it plainly appears — that obstructed per- spiration is very hurtful to the gouty. And the dif- ferent things which relieve these patients, can hardly act in any other way, than by promoting the perspi- ration and due distribution to the surface. Of this kind are plentiful and warm clothing, especially to the pained parts, from which almost all gouty per- 2 A 186 sons experience relief: also the tepid and even the hot bath, and frequent and powerful frictions, from which many derive the greatest assistance; and some, very much broken by the disease, have recovered the use of their limbs which they had almost lost. There is no occasion to repeat what has already been said respecting the benefit accruing in this dreadful disease, from the summer heat. It may be reason- ably collected from all these facts, as it seems to me, that a free perspiration is especially necessary in curing this disease; and we have before proved, that a climate moderately warm, eminently effects that purpose, because the sick, however greatly broken down and debilitated, can receive the advantage of it as long as they please without danger or detri- ment. I would therefore recommend a change of climate to the gouty, for these reasons particularly: that all the injury which arises from our winter, may be avoided, and the advantage, whatever it may be, which the summer season affords, might be continu- ed, and so that the perspiration and due determina- tion of the fluids to the surface, might be promoted; or if it should have been checked, so that it might be restored. 187 Another argument may be added to these, and though it is an uncertain one, and does not appear at all accurate, yet I do not think on that ac- count that it is irrelevant. We have before observed that the seeds of gout exist in the constitution of some persons; but since the nature of this predispo- sition as yet is concealed, it can hardly be expected that a powerful remedy will be found by which it can be corrected or extirpated. ** For since in this disease (as Sydenham has judiciously mentioned) its cause exerts such an influence over the constitution as to render its very nature, new as it were, no ra- tional being could suppose that a slight or temporary alteration either produced by medicines, or by a par- ticular diet, could produce a radical cure; but the general habit of body must be brought into a different condition, and the entire man as it were subsequently re-organized." But if the condition of the system is entirely or almost entirely changed, it is not impro- bable that the peculiar disposition would be altered or corrected. It is known, that certain changes which the constitution undergoes, bring that disposition into view: for in the state of infancy or boyhood, it rarely shows itself; while the disease generally makes its attacks in manhood. The constitution therefore 188 undergoes in that age, certain changes favourable to this disposition. Therefore we might hope that other changes would be able to expel or correct a gouty disposition. Now the constitution of the system is most altered by a change of climate: and experience plainly shows that travelling into warm countries would be not only safe in this disease, but even very useful and pleasant to the patients. There is a very remarkable case, and very appo- site to these observations, which the celebrated Van Swieten has mentioned in his Commentaries, of a man who in the thirty-first year of his age, laboured severely under gout, and lost almost entirely the use of his hands and feet. In this condition he took a voy- age to the East Indies, with a view to derive benefit from the climate. He returned to his native country after a lapse of three years, and in consequence of the heat of the air, without the use of any other re- medies, he lived healthy and perfectly free from gout. A similar case is related by the illustrious Haller, of Lord de Poihcy, who when an old man, and al- ready severely afflicted with gout, went to the warm islands of America, where he lived many years with 189 the effect of being freed from gout and all the other evils of old age, and recovered his former health. A case similar to this I received from a very learn- ed physician, who often saw the patient while he lived abroad. A nobleman laboured for many years under gout, until at length the disease so much in- creased, that he was grievously afflicted the greatest part of the year. The patient had used many reme- dies without effect. He lived for a long time on a diet of milk alone. The disease however daily grew worse. He made a journey into Italy, where in a short time he had a most severe paroxysm, (though of short duration). Afterwards, however, he lived free from the disease, and still lives after many years. It must be observed, that this patient remained only two years in Italy, and while he staid there he indulged in a somewhat more generous diet than before. 190 SECTION V. Of invigorating old age. — The signs and effects of declining life in old persons, and the particular consequences of the depreciated functions of the system. — Reasons why a change of climate may be expected to relieve them, and produce a general invigoration of the fading body. — Of the injurious effect of a cold and humid climate upon old people, and the advantages to be derived from travelling to warm countries. I MAY advance in this place, a few observations respecting the relief of old age, and protracting hu- man life beyond its ordinary limits, by means of the influence of a change of climate. They will neither be useless nor foreign to the subject of this discourse. Some physicians of eminence suppose, that old age itself is a true disease, which can derive relief from our art. Others indeed, contend that old age is a natural and inevitable condition of life, and that there- fore it can neither, be relieved nor rendered a disease, by means of human art. It is not my intention to enter into a discussion of this question, for it would be both useless and impertinent to my subject, to I 191 do so. Whether it be a disease, or a natural state, it is very certain that old age brings with it many in- conveniences, renders the system liable to many dis- orders, evidently diminishes all the natural powers both of mind and body, and sooner or later brings on death itself. This state therefore, stands in great need of all the precautions and assistance that medi- cine can afford. For it is the province of physicians not only to cure diseases, but to maintain health, and as far as is allowed to mortals, to preserve and prolong life. The science of medicine would conse- quently be very imperfect, if it could not supply any remedies calculated to accomplish this end. Espe- cially since there are some evil disposed persons, who contend that our healing art, sometimes shortens the span of human life. I am not indeed acquainted with any remedies, which are endued with the power of making us young again: yet I do not at all doubt, that reme- dies might be found sufficiently efficacious to be able to ward off immediate old age, and to prolong life for some years beyond its natural bounds, as well as to keep the health and powers of the system but little impaired. But such a virtue cannot be expect- 192 cd from the use of medicine for a short time. To achieve such an effect on the system, it is not only necessary that an efficacious remedy should be em- ployed, but that it should be long continued, and that the general constitution should undergo a proper and almost entire revolution. In many cases, where the general system is con- taminated by some vice, and is threatened with some serious danger, a change of the whole habit of body, often succeeds very happily. It is very well known to every one, than an intemperate or improper mode of life, often brings on a protracted state of ill health, and premature old age. Reason and experience there- fore both prove, that a proper kind of life can pre- vent those inconveniences, maintain health, and re- tard the approach of old age, as well as protract life. How much a proper change in the mode of life conduces to this effect, Cornaro has very clearly evi- denced. After having past his fortieth year, he felt that his constitution was in a manner broken down, and debilitated by his intemperate kind of life: he took leave of his former habits, led a sober and tem- perate life, recovered his pristine vigour, and com- 193 pleted his hundredth year, without the health of his body or the faculties of his mind being impaired. We have before said that a change of climate pro- duces powerful effects on the human body: and if a man should live sufficiently long under another sun, it is not improbable that his constitution would be entirely changed. Various are the arguments which influence me in adopting the opinion, that a change to a warm climate would be very useful to most old persons. No rational creature can suppose that a change of climate, or any other remedy, will banish old age forever, or that it could prolong hu- man life to eternity, or even for a long series of years. I shall not promise so miraculous a remedy. But there are many who find their health broken, and their powers impaired, and who feel death close upon them, who would seize with the greatest eager- ness a remedy, by which life could be extended only for a few years, and which might in some measure regenerate the languid and impaired powers of the system. In our opinion, there are some obstacles to the long continuance of human life, in every part of the 2B 194 globe; but if there be any difference, they are greater in our northern countries than in the regions of the torrid zone. But we have before remarked, that a warm climate produces much more powerful effects upon travellers, than upon men who live continually under its influence. If any one is continually accus- tomed to the useful remedy it affords, he evidently loses whatever degree of benefit might be expected from its operation. Nay, I could easily believe, that the immoderate use of this remedy, would not only do no good, but would, in many cases, prove very injurious. If any one of our inhabitants, healthy and robust, and in the bloom of life, was to seek more fervid climates, where he might live, his life would not only not be prolonged, but perhaps would be curtailed, and he would prepare for himself a pre- mature old age — melancholy examples of this kind, are daily presented to our view. We should sedu- lously attend, respecting this remedy, to what Celsus formerly judiciously admonished, with regard to others; namely, that we should take care lest in our efforts to preserve health, its real interests were not destroyed by injurious cautions. I shall endeavour therefore to show, what changes 195 occur in old age, the way in which our climate is pernicious to old persons, and the reason why tra- velling into warm countries should be recommended to them. I do not design to treat here of all the evils particularly, to which old age, in these northern countries, is subject, and which might be prevented, relieved or cured, by a change of climate. 1 intend to make some remarks only upon those changes and differences that are natural to old age, and which attack sooner or later the healthiest and most vigor- ous, break down and waste away the constitution, and finally sweep them from the busy scenes of life. In the progress of years, the human body suffers various alterations which injure all the powers and natural functions of the system; consequently many inconveniences are brought upon the aged. These changes affect the whole system, and undermine and weaken it in every part; they especially affect the nervous system, blunt the understanding, diminish the strength and energy of the mind and body, ren- der the solid parts stiff and hard, and greatly impede the motion and distribution of the fluids. All these evils evidently increase by degrees; yet it is very difficult to explain their beginning and origin, or t© 196 detect which is the cause of the others. If we begin from the impeded distribution of the fluids, a ques- tion arises, why this is disturbed, if the solid parts and the moving powers remain sound, natural and entire? Or, if we begin from the induration and atony of solid parts, and especially of the arteries and muscles, it will be difficult to assign a reason why these have become indurated, and have lost their powers, if the distribution of the fluids is properly promoted, and the nervous energy not diminished. Finally, if we begin from a defiiciency of the nervous power itself, (whence doubtless all the other evils spontaneously flow), we should explain, why this is deficient, if the motion of the blood and the rest of the functions of the animal machine are performed properly and in the usual manner. For the action of the heart and the nervous energy reciprocally sup- port each other. It must therefore be acknowledged, that the human body is a circle, the beginning and the end of which are as yet concealed, and perhaps for a long time will continue unexplored. All things that are necessary to life and for the health and increase of the body, are not accurately understood; it can hardly be expected therefore that the cause of any default in them, should be nicely comprehended. 197 Yet we do know many things that are necessary to life and growth, and which support the strength and hcahh of the body; we are acquainted too with rriany which are inimical to all these, which diminish the powers, destroy the health, waste the body, and pave the way for death itself. We know moreover that all these increase each other, so that the consti. tution is daily running into a worse condition. But all the changes which arise from old age, may be reduced to three heads; to impaired nervous en- ergy, and induration of the solid parts, and an ob- struction of the free distribution of the fluids. Of each of these effects we shall now proceed to treat more particularly. The first signs which generally accompany and denote incipient old age, are observ- ed to arise from impaired nervous power. All the senses both external and internal, by degrees are rendered more obtuse. Sight, hearing, smelling, taste, are sensibly deficient; hence most old persons dislike light and unadulterated food, which they be- fore were fond of — and crave a more savoury, salt and high seasoned diet. The cheerfulness of youth gives way by degrees to the gravity of age. The strength and activity of the body, are also sensibly 198 diminished; hence most old men leave off all the more powerful exercises, and very willingly ex- change the toil of business for a life of tranquillity and ease. Upon still more advanced age, the strength of the muscles is daily more and more diminished, until at length confirmed old age causes a loss of almost all the uses of the limbs. The faculties of the mind also by degrees waste away. The imagina- tion is depressed, and memory totters; at first in- deed, recent ideas easily escape it, although old ones which it formerly imbibed it very tenaciously retains. But afterwards all ideas, both old and recent, are dropt from the memory altogether, and then the judgment is destroyed. — The solid parts of the body become hard: the cellular texture is not only harder so as to resist the knife, but has obtained a greater power of adhering. Hence the skin, which in youth was soft, smooth, and equal, by degrees becomes hard, and rough. The numberless invisible pores are contracted, and altogether closed up; hence per- spiration is obstructed, and the skin acquires a pecu- liar dryness. The arteries of old persons become thicker, more rigid, and even narrower, and many of the smaller ones are gradually closed up. The veins also acquire a greater thickness and strength 199 than in youth, but never in the same proportion as the arteries. Hence, from the greater resistance and diminished impetus, (to wit, by the moving powers being now impaired), the motion of the blood is slower; so that the veins of old persons become larger and not unfrequenily varicose. From this cause also, and the diminished irritability of the heart, (from a defect of nervous energy), the pulses beat more slowly. The brain itself, the nerves, all the viscera — become indurated, so that the muscular fibres often become almost altogether converted into a very hard tendinous substance. This induration evidently arises from a deficiency of the fluids, which cannot now, as formerly, flow through the smallest vessels, by this time contracted and closed. The same reason might chiefly be given, for the de- bility of the muscles, and the decrease of the whole body, which are observed in old age: For however large, corpulent and robust bodies may be in the first stage of old age, they become in the last, in- active, and ahogether debilitated. If the vessels which used to carry blood to any part, are contract- ed, or closed, so as to convey no blood, or but an inconsiderable quantity, it is evident that such part cannot be nourished as before; it is not surprising 200 ' therefore, that it pines away, and loses the powers which it formerly possessed. Besides, many vessels, and lacteal glands of the mesentery, are obliterated in extreme old age; and thence perhaps it is probable that a much less quantity of nutriment will be conveyed to the blood, from the same food. — With regard to the obstructed motion and distribution of the blood, there is no doubt. A defect of nervous energy in consequence of the debility of the moving parts, the greater resistance of the arteries, and from the con- striction or choaking of innumerable minute vessels, and cutaneous pores, — it is evident that the blood does not flow freely through the whole body, as be- fore. All, nearly, of the minute excretions, and some suppressed ones, the dryness and fading and hard- ness of the body, demonstrate the fact beyond the possibility of doubt. The perspiration in old persons is very much lessened, and often almost watery. Their bowels also are generally observed to be slow or inactive. Hence, according to many and very celebrated authors, an acrimony of the fluids is produced, from a retention of those parts which ought to be excreted and passed out. But the na- ture of this acrimony, so far as I know, is not ac- curately understood. I will not deny that many 201 disorders happen in the fluids of old persons: And from the deficiency of the other natural powers, which were wont to prepare properly the blood, it is not improbable, that it will become feeble or other- wise diseased. Old persons are sometimes liable to disease, evidently the consequence of a defect in the motion of the blood, namely, necrosis, or gangrene, which generally attacks first the feet, afterwards the legs, and induces though slow, yet certain death. The reason therefore is plain, why our cold, moist, and variable climate is unfriendly to old people. In the first place it injures the nervous system, and diminishes the power and activity both of body and mind: Hence the due distribution of the fluids is impeded, and the atony and hardness of the solid parts increased. Moreover, cold and moist air (as we have already remarked) obstructs, directly and immediately, the perspiration, and the free determi- nation to the surface. Cold also causes an induration and stiffness of the external skin, and the other solid parts. But all these things occur naturally to old persons, and when they do happen (as wc have re- marked above) they increase each other. 2C 202 From the history of old age it may be gathered, that the evils which occur to it, especially require three things: namely, to sustain and nourish the ner- vous power, or, if it is already depreciated, to re- store it: to prevent or remove an excessive hardness of the solid parts, and promote the due distribution of the blood. If all these things can be exactly ac- complished as we would desire, there is no doubt but that the former vigour and complete youth would be restored. But if they are only partially achieved, the energy and power will be renovated in some measure, delay the immediate approach of old age, and perhaps prolong life for many years. I do not know any remedies which answer these intentions better than a change of climate, by travelling in warm countries. Nor is it a matter of small importance that this remedy is both safe and pleasant at the same .time, for all the evils of old age. We plainly see that all these disorders increase each other; yet we never know which one is the cause of the rest. It is of the greatest importance in curing any disease, that a remedy should be applied in the first place to its causes. But if to any of the evils to which old persons 203 are subject a remedy can be applied, it is but rea- sonable to expect that the general system would de- rive benefit from thence; in this way the powers of nature might be somewhat recruited, and the other evils of old age, might, in some measure, be re- lieved. There is no occasion to sny of how much use warm air is in exciting and nourishing the nervous energy. The healthiest and most robust, who stand in need of no such assistance, experience new ac- tivity both of mind and body, from this source. But to the debilitated and the feeble, worn out by old age, it restores the decaying powers, and as it were, fills up the chasm of wasted life. It replenishes and preserves the powers of the muscles, sharpens the obtunded senses, stirs up the languid and almost stagnant circulation of the blood, quickens the pulses (in old persons slow) and promotes the due motion and distribution of the fluids throughout the whole system. It restores also all the secretions and excre- tions, now diminished and almost suppressed, more especially the perspiration. In this manner, therefore, it would be greatly beneficial to old persons. 204 Nor does it exert less power in preventing or cur- ing that hardness of the skin and all the solid parts, which brings such evils upon the aged. Cold con- stricts and hardens the skin and solid parts; but mo- derate heat relaxes and softens them, as we plainly see. If an old person therefore would go abroad into moderately warm countries, the mild air would sen- sibly render his hard, rough, dry, and almost imper- vious skin, smooth and penetrable; again, it would open the numberless more minute vessels now con- tracted, and almost closed, and open the way for the blood and other humours to many parts of the body, almost dried up for the want of the vital fluid. Hence all the natural secretions and excretions now defi- cient, are promoted, and the power, contractility and softness are restored to the indurated and tendinous muscles, now trembling, weak, and almost paraly- tick. Nor is there any doubt but that the nervous system derives the happiest effects, from this reno- vation of all the powers of the body. It is known that to most persons, a free distribution of the fluids and perspiration, ensures the greatest strength and activity of mind and body. Nor would it happen otherwise in old persons. In consequence of the ner- vous system being in this way regenerated, the whole 205 system would be reanimated. Hence as before, the hardness of the solid parts, and especially of the skin and arteries, is in some way or other overcome, the powers of the system are increased, the return of blood to the heart is accelerated in consequence of the di- minished resistance, the pulses beat quicker, and the blood is properly propelled through the minute and extreme vessels; so that it opens for itself a passage through the almost closed up vessels, and renders the hard, stiff and dry parts, soft, flexible, and ener- getick as before. Now if this may be effected by the perspiration and distribution to the surface being greatly promoted, it appears reasonable how a change of climate might be of service to the aged. For free perspiration, how- ever excited, relaxes and moistens the skin; hence its hardness and dryness in old age is diminished or corrected, and the distribution of blood is rendered more easy to the external parts. It increases the powers of nature therefore, and replenishes defi- ciences. It is also very favourable to the nervous system, and produces energy of body and cheerful- ness of mind. It perfectly answers the three indica- tions for cure which we have advanced, and these 206 also reciprocally promote each other. From all these circumstances then, it may be collected, a priori, that a change of climate would be of infinite service to the aged. This theory is confirmed, from analogy of many things which are beneficial to old persons, and which may clearly be referred to our indications. We recommend in the first place to nourish and support the nervous energy: now the liberal use of wine tends to produce this effect; and experience satisfactorily proves, that wine, however injurious it may be to young persons, is, when moderately used, not only safe for the aged, but of the greatest utility; so that it has been esteemed, and not unjustly, the milk of old age. To confirm this it is hardly neces- sary to adduce the authority of great names. If how- ever there were occasion for such adventitious assis^ tance, the most renowned Sangrado (of whose fame there is no one that has not heard), affords remark- able proof. For after waging, th'-ough the course of a whole life, a fierce and implacable war against all generous drink, upon the advance of years, he was vanquished in the fight, and, forced by dire neces- sity, he implored favour and protection from his 207 « former execrated enemy. If any one is disposed to reject the instance of Sangrado, let him yield to the wise Le Sage, who was not less deeply versed in the medical art than in a knowledge of mankind. To the other indication, of promoting the perspiration and distribution of the fluids to the external parts, warm clothing is evidently necessary. And it is well known to every person, that this is extremely useful to old people, who should use flannel shirts. Fric- tions also, and moderate exercise, especially gestation, which tends to the same effect, is greatly serviceable to old people: so also is the tepid or warm bath, from which many aged persons derive great help. But the benefits which the summer season brings to old people, strengthen the theory more than any thing else, and are the best proof of the utility to be expected from a warm climate. Upon the approach of summer all the evils which harass the aged in the winter, disappear almost entirely, and old age being kept a little in check, the scintillating and almost extinguished flame of life, is seen to be animated in them anew. Upon the return of winter, the former evils again, and now more grievously, press upon them. If any benefit therefore is derived from our 208 summer, a climate enjoying a perpetual summer, promises much more permanent assistance. Finally, experience proves that this hope of reliev- ing old age in some degree, and extending life be- yond its natural termination, is neither vain nor futile* For there are many instances of old persons having gone into warmer countries, and having de- rived new vigour from the change, and prolonged their ebbing life. Some Europeans who have gone to India, experienced unexpectedly this beneficial relief. It is said that the Spaniards and Portuguese, when they feel the presages of old age, not unfre- quently go to Brazil or other parts of South Ame- rica, and thus revive their wasted strength, and sometimes protract life for twenty years or more. " The fame of the healthiness of Brazil (says Piso in his natural and medical history of Brazil) invited formerly not a few old persons and others in ill health, to take advantage of the air and water of the country, as though they were two of the most pow- erful preservatives of life and health. For the inha- bitants soon arrive at maturity: grow old slowly, and without hoariness or baldness. Hence it is that long after the hundreth year of age, they enjoy, not only 209 the American, but even Europeans themselves, a green old age, so that the whole country deserves to be called the country of longevity.'' Nay it is said that lost fecundity is restored in the warm islands of America. Which if it be true, plainly proves how powerfully warm air acts in reviving the powers of the system. A question yet remains to be considered: at what age travelling into warm countries may be under- taken with the greatest benefit. I doubt whether any age can be particularly designated; for the use of travelling depends on the state of the constitu- tion and not on particular periods of life; besides, some grow old sooner and others later. Authors divide old age into incipient or green, and decrepit. They calculate the first from the forty-ninth year, or from the time when men begin to grow gray, and use spectacles, that is to say, from the grand climacterick of life; the other is computed from the end of this to the last hour of existence. In the first, but few and slight inconveniences are experienced; yet, they may be easily observed, and plainly indicate universal and approaching decay. But all the facul- ties both of the mind and body, as yet remain. 2D 210 Muscular motion is but little diminished; the facul- ty of generating, and the appetite for food and di- gestion, continue: while in decrepit old age all these quickly run on to deterioration. All the powers of the mind are daily diminished, and at length alto- gether disappear; all the functions of the body lan- guish, and at length cease to operate. It is however observed, that these changes happen sometimes sooner and sometimes later; some retain all their powers and functions, even the faculty of genera- ting, almost to the hundredth year; some preserve the form of the body and all the senses both exter- nal and internal, unimpaired till the seventieth or eightieth year. Many persons most manifestly suffer a deterioration of all their powers, before the seventieth year. Before the fiftieth year however, scarcely any sensible alteration takes place. I can hardly believe then, that a change of climate is re- quired before the fiftieth year; but after it, there is no doubt that in many cases it would be of the greatest service. It is much easier in this, if I be not mistaken, as in other instances, to prevent the evils than to cure them; and therefore travelling may be begun with the greatest advantage between the fiftieth and sixty-fifth years of age, for the most 211 part perhaps about the sixtieth, and sooner or later according to the strength and constitution of the person. But this depends on different circumstances, as a congenital and perhaps hereditary constitution; for longevity is much more frequent in some fami- lies than in others; yet it principally depends upon the mode of life, and innumerable other adventitious causes. — Yet I do not in the least doubt that travel- ling into warm countries, would be extremely bene- ficial to old persons already become decrepit, and it is perhaps, the only remedy by which their pow- ers may be restored, and their lives prolonged. Lastly, it is to be inquired how this curative in- tention derived from climate, is to be answered, and what particular countries should be sought by the aged. A country warmer than our native clime, en- joying a pure, mild and benign air, and in other respects healthy, should always be chosen: again, upon the approach of old age, a still warmer country should be sought: nor do I think that an old person should despair altogether till even the hottest climates have been tried. If any one of our inhabitants who is growing old, should go to Spain or Italy and re- side there, I have no doubt but that he would expe- 2\^ rience the most beneficial effects from the change, and would banish old age, or at least all the evils of old age, for many years. But in process of time, these would doubtless assail him again; when, if he should seek a still hotter climate, he would by the same reason, receive new vigour from it; so that when old in Spain he might, by being transported into South America, derive assistance from that change, and be again renovated. Thus we may indulge the pleasing expectation, that health may.be procured even in the hottest climes on earth; that man, when threatened with the decrepitudes of old age, may avert, or at least alle- viate them, by deserting his native soil; and that he might prolong a life, the shortness of which is a source of perpetual and querulous regret, for twenty or perhaps for thirty years, by availing himself of the friendly influence of a foreign and more genial sun. THE END. % 4 i % I s. j^um