wis «l is it ■ ifii m .-^J' ^' ,".. y;.-. '; <*■■■ j,.,' V!*«-T 1*^1 -xT mm. zii^ SNvsm^ K H ON CATARACT, OPERATION REMOVAL BY ABSORPTION, THE FINE NEEDLE THROUGH THE COENEA. ARTHDR JACOB, M.D., F.R.C.S., PROFESSOR OF ANATOMY AND PHYSIOLOGY IN THE ROYAL COLLEGE OF SURGEONS IN IRELAND, AND SURGEON FOR DISEASES OF THE EYE TO THE CITY OF DUBLIN HOSPITAL. DUBLIN: PRINTED AT THE MEDICAL PRESS OFFICE. 1851. CATARACT. STRUCTURE OF THE LENS NATURE OF ITS OPACITIES. It is scarcely necessary to state that cataract is the name given to that disease of the eye in which blindness is caused by loss of transparency in the crystalline lens ; and under that name, therefore, all opacities whatever of that pai^t should be considered. Certain appearances, generally accompanied by defective vision, have been denominated glaucoma ; but if it is meant to attribute these appearances and the defective vision which accompanies it to any loss of transparency in the crystalline lens, the term should not be used, the disease being in that case only a form of cata- ract. The application of two different names to the same disease is calculated to create confusion. T am not here, however, going to inquire what the disease called glaucoma is, I only want to have it settled that it is not cataract, or that if it is, it should be so called. Notwithstanding all that has been already written on the subject, I think it is necessary to preface what I have to say respecting changes in structure of the crystalline lens by a description of that part in its natural and healthy state. It is, as every one knows, what is called a double- OS CATARACT. convex lens, or rather like two plano-convex lenses united at their plane surfaces ; for its anterior surface is much less curved than its posterior : if not so, we should have it touching the iris, and perhaps interfering with the contrac- tions of the pupil. Its minor axis measures about seven-for- tieths of an inch ; or in other words, it is seven-fortieths of an'inch thick; being about one half the length of its major axis or breadth. If we consider the surfaces of the lens to be spherical, we may say that the posterior is a segment of a smaller sphere than the anterior j or in other words, it is much more convex : the surfaces are not, however, strictly speak- ing, spherical, but perhaps spheroidical, or even elliptical or hyperbolical. These curvatures, it must also be recol- lected, are very different at different periods of life. In youth, perhaps we may say to the period of puberty, they are more curved, but from this period to forty-five or fifty, they remain stationary, when they become less so ; in fact, the lens in children is much thicker or more convex, while in old persons it becomes less convex, thinner, and flatter. The consideration of these changes are of great importance in a practical point of view, because although the greater convexity in early life does not seem to render the eye myopic, the flattening in advanced life causes it to become presbyopic. The greatest difference also often exists in different individuals in this respect, causing short or long sight throughout life, and even in the same individual the lenses appear to be frequently unequal, causing serious imperfection of vision. In incipient cataract, the curva- tures of the lens often alter, sometimes causing persons to lay aside their spectacles, and sometimes to change them for others of a different focus. I am of course aware that the differences above alluded to may be attributed to other causes, but the undisputed fact that the lens becomes much flatter as we advance in life, and that at the same time the ON CATARACT. 3 eye becomes presbyopic, appears conclusive as to the cause and effect. With a view to determine the causes of the changes which take place in vision from age or alteration in structure, it is necessary to consider the refractive power of the crystal- line lens. The refractive power of the capsule has not been ascertained, but it is probably greater than any other of the transparent parts, although from its being so very thin it has little effect in altering the direction of the rays of light. The body of the lens is not of equal density throughout, being scarcely denser than water at the sur- face, but increases gradually in density to the centre, so that probably the rays do not pass through it in straight lines, but more or less curved. The mean refractive index is, however, held to be 1.384, and its principal focal length in air about one-third of an inch, perhaps its power may therefore be considered half way between water and glass. The density, and consequently the refractive power of the lens, becomes greater in advanced life, and for anything we know to the contrary, there may be some difference in this respect, as well as in the curvatures of the surface, in different individuals ; so that, whether from this cause, or from some peculiarity in organization, or from defect of adjustment in the size or place of the pupil, very serious imperfections of vision frequently occur, and are often con- founded with incipient cataract or impartial amaurosis. I every day meet with cases in which one eye is almost use- less from some of these causes or a combination of them, and in which I know there is no loss of transparency of the lens or diminution in sensibility of the retina. In such cases relief may sometimes be afforded, especially in near- sighted persons, by the use of glasses calculated to com- pensate for or neutralise the defect ; or perhaps we may effect some improvement by influencing the state of the 4 ON CATARACT. pupil by external applications. Imperfections of vision from the causes here noticed sometimes occur at the com- mencement of the period when the lens begins to flatten, and disappear in a year or two when the change in form arrives at its utmost extent. Having premised so much with respect to the form and refractive power of the lens, it may not be superfluous to repeat what I have already stated respecting this part of the eye in the Cyclopaedia of Anatomy ;* being convinced that a correct knowledge of the structure of any part is the first requisite towards a correct comprehension of the changes It undergoes from disease, and that no brief or meagre description is sufficient to convey that knowledge : it is as follows : — "It has been already stated that there is a double con- vex lens within the sphere of the eye, at a short distance behind the external lens or cornea. This is the crystalline lens or crystalline humour, which gives additional conver- gence to the rays of light transmitted through the pupil. It is placed in a depression, formed for its reception on the anterior, compressed, or truncated portion of the vitreous humour, where that body approaches the back of the iris, * For the article Eye in the Cyelopsedia of Anatomy here alluded to, I venture to take this opportunity ot claiming a fair consideration at the risk of being charged with undue partiality towards it, because it was prepared by myself. Articles in encyclopaedias are frequently looked upon as mere compilations, and are therefore seldom referred to as deposi- tories of original information, but many of those of the Cyclo- paedia of Anatomy were of the latter description. Upon the article on Anatomy of the Eye, no expense was spared by the then publishers, and I can safely say that no trouble was spared by me. I therefore can refer those who attach value to information derived from this source to it with confidence. ON CATARACT. 5 and constitutes part of the boundaries of the posterior chamber of the aqueous humour. In this depression it adheres firmly to the hyaloid membrane, and from the ves- sels of that structure derives its nutriment. This double convex lens does not present the same cur- vature on both surfaces, the anterior being less curved than the posterior, in the ratio of about four to three. Attempts have been made to determine with accuracy the nature of these curvatures, first by Petit, and subsequently by Win- tringham, Chossat, and others. The results of the numerous experiments of Petit lead to the conclusion, that the an- terior curvature is that of a portion of a sphere from six to seven lines and a half in diameter, the posterior that of a sphere of from five to six lines and a quarter. From the same source it appears that the diameter is from four lines to four lines and a half, the axis or thickness about two lines, and the weight three or four grains. 1 am, however, inclined to agree with the observation of Porterfield, that, ' as it is scarce possible to measure the crystalline and the other parts of the eye with that exactness that may be depended on, all nice calculations founded on such mea- sures must be fallacious and uncertain, and therefore should, for the most part, be looked on rather as illustra- tions than strict demonstrations of the points in question.' The method by which Petit arrived at these results must render them of doubtful value, the curvatures having been determined by the application of brass plates cut to the requisite form. The results of Chossat's experiments, con- ducted with great care, and with the assistance of the me- gascope, are thus stated by Mr. Lloyd in his treatise on Optics : — ' This author has found that the cornea of the eye of the ox is an ellipsoid of revolution round the greater axis, this axis being inclined inwards about 10 deg. The ratio of the major axis to the distance between the foci in the generating ellipse he found to be 1.3 ; and this agree- ing very nearly with 1.337, the index of refraction of the aqueous humour, it follows that parallel rays will be re fracted to a focus, by the surface of this humour, with mathematical accuracy. The same author found likewise 2 A 6 ox CATARACT. that the two surfaces of the crystalline lens are ellipsoids of revolution round the lesser axis ; and it is somewhat remarkable that the axes of these surfaces do not coincide in direction either with each other, or with the axis of the cornea, these axes being both inclined outwards, and con- taining with each other, in the horizontal section in which they lie, an angle of about o deg.' It must not be forgotten that these observations apply to the crystalline of the ox, not to that of man, and also that, as Chossat himself admits, the evaporation of the fluid part of the lens, or the absorp- tion or imbibition of the water in which it is immersed, may materially alter the curvature. I cannot myself believe it possible to separate a fresh lens in its capsule perfectly from the hyaloid membrane without injuring its structure, and endangering an alteration in its form. Haller states that Kepler considered the anterior CvOnvexity to approach to a spheroid, and the posterior to a hyperbolic cone. Wintringham states the results of his inquiries as to this matter as follows : — ' In order to take the dimensions of the eye of an ox, I placed it on a horizontal board and applied three moveable silks, which were kept extended by small plummets, so as to be exact tangents to the arc of the cornea, as well at each canthus, as at the vertex ; then applying a very exactly divided scale, I found that the cord of the cornea was equal to 1 .05 of an inch, the versed sine of this cord to be 0.29, and consequently the radius of the cornea was equal to 0.620215 of an inch. I then carefully took off the cornea, and replaced the eye as before, and found, by applying one of the threads as a tangent to the vertex of the crystalline, that the distance between this and the vertex of the cornea was 0.355 of an inch. Afterwards I took the crystalline out without in- juring its figure, or displacing the capsula, and then ap- plying the threads to each surface of this humour, as was done before to the arch of the cornea, I found that the cord of the crystalline was 0.74 of an inch, and its versed sine, with respect to the anterior surface, to be 0.189 of an inch, and consequently the radius of this surface was 0.45665 of the same. In like manner the versed sine to ON CATARACT. 7 the same cord, with respect to the posterior surface of the crystalline, I found to be equal to 0.38845 of an inch. Lastly, I found the axis of the crystalline and that of the whole eye from the cornea to the retina to be 0.574, 2.21 respectively. Whatever doubts may be entertained re- specting the accuracy of the measurements of the lens, there can be none that the form is different at different periods of life, in the human subject. It also appears to differ in different individuals at the same period of life, and probably the curvature is not the same in both eyes. In other animals the difference in form is most remarkable. In the human foetus, even up to the ninth month, it is almost spherical. Petit stales that he found the anterior curvature in a foetus of seven months, a portion of a sphere of three lines diameter, and the posterior of two and a half, and the same in a new-born infant. In an infant eight days old, the anterior convexity was a portion of a sphere of four lines, and the posterior of three. All anatomists concur in considering the lens to approach more to a sphere at this period. In childhood the curvatures still continue much greater than in advanced life ; from ten to twenty probably decrease, and from that period to forty, forty -five, or fifty, remain stationary, when they become much less ; being, according to the tables of Petit, portions of spheres from seven to even twelve lines in diameter, and on the posterior of six or eight. Every day's observation proves that the lens becomes flattened, and its curvatures dimin- ished as persons advance in life. It is seen in dissection, when extracted by operation, and even during life ; the distance between its anterior surface and the back of the iris being so great in some old persons, that the shadow of the pupil may be seen upon it, while at an earlier period it actually touches that part of the membrane. This dimi- nution of the curvatures of the lens commences about the age of forty-five. Petit found the anterior convexity vary- ing from a sphere of about seven to twelve lines diameter, and the posterior from five to eight in persons from fifty to sixty-five years of age. The alteration in power of adap- tation, and the indistinctness of vision of near objects which 8 ox CATARACT. takes place at this period, is probably to be attributed to this cause, although a diminution of the muscular power of the iris, and consequent inactivity of the pupil, may contribute to the defect. It is also to be recollected that the density of the lens is much increased at this period, and that the young person whose lens presents greater curva- tures does not require concave glasses, as the old person requires convex ones. The state of the eye, after the re- moval of the lens by operation for cataract, proves that it is a part of the organ essentially necessary for correct vision. A^'hen the eye is in other respects perfect, without any shred of opaque capsule, any irregularity or adhesion of the pupil, or any alteration in the curvature of the cornea, as in young persons who have had the lens pro- perly broken up with a fine needle through the cornea, vision is so good for distant objects, that such persons are able to pursue their common occupations, and walk with safety through crowded streets, but they require the use of a convex lens, of from three and a half to five inches focus, for reading or vision of near j old persons, however, generally require convex glasses on all occasions after the removal of the lens. That the curvatures of the lens are frequently different in difierent individuals may be inferred from the frequency of short sight, or defective power of adaptation, not attributable to any peculiarity of the cornea. Petit states that he found lenses of which the two convexities were equal, and others of which the an- terior was greater than the posterior, and more tl.an once, one more convex on its anterior surface in one eye, while that in the other eye was in a natural state. He also oc- casionally found the lens as convex in the advanced period of life as in youth. I have repeatedly observed the per- fection of vision and power of adaptation much greater in one eye than the other in the same individual, without any defect of the cornea, pupil, or retina; and occasionally have found young persons requiring the common convex glasses used by persons advanced in life, and old persons becoming near-sighted, and requiring concaves. The an- nexed letters show the difference of curvature at the dif- ON CATARACT. 9 ferent periods of life, as represented by Sommerring. C is the lens of the fcetus ; B, that of a child of six years of age J and A, that of an adult. The colour of the lens is also different at different periods of life. In the foetus it is often of a reddish colour ; at birth and in infancy it appears slightly opaque or opaline ; in youth it is perfectly transparent ; and in the more ad- vanced periods of life acquires a yellowish or amber tint. These varieties in colour are not visible, unless the lens be removed from the eye, until the colour becomes so deep in old age as to diminish the transparency, when it appears opaque or milky, or resembling the semitransparent horn used for lanterns. The hard lenticular cataract of ad- vanced life appears to be nothing more than the extreme of this change of colour, at least when extracted and placed on white paper it presents no other disorganization ; but the lens of old persons, when seen in a good light and with a dilated pupil, always appears more or less opaque, al- though vision remains perfect. The depth of colour is sometimes so great, without any milkiness or opacity, that the pupil appears quite transparent although vision is lost. This is perhaps the state of lens vaguely alluded to by authors under the name of black cataract. The consistence of the lens varies as much as its colour. In infancy it is soft and pulpy, in youth firmer, but still so soft that it may be crushed between the finger and thumb, and in old age becomes tough and firm. Hence it is that in the earlier periods of life cataracts may be broken up completely into a pulp, and absorbed with certainty, while in old persons they adhere to the needle, unless very deli- cately touched, and are very liable to be detached from the capsule and thrown upon the iris, causing the destruction 10 ON CATARACT. of the organ. On this account, therefore, the operation of extraction must generally be resorted to in old persons labouring under this form of cataract, while the complete division of it with the needle and exposure of the frag- ments to the contact of the aqueous humour secures its removal by absorption in young persons. It must not, however, be forgotten that the softer lenticular cataract occasionally occurs in advanced life. The crystalline lens is a little heavier than water. Por- terfield, from the experiments of Bryan Robinson, infers that the specific gravity of the human lens is to that of the other humours as eleven to ten, the latter being nearly the same as water ; and Wintringham, from his experiments, concludes that the density of the crystalline is to that of the vitreous humour in the ratio of nine to ten ; the spe- cific gravity of the latter being to water as 10024 to iOOOO. The density of the lens is not the same throughout, the surface being nearly fluid, while the centre scarcely yields to the pressure of the finger and thumb, especially in ad vanced life. Wintringham found the specific gravity of the centre of the lens of the ox to exceed that of the en^ tire lens in the proportion of twenty seven to twenty-six. The refractive power is consequently greater than that of the other humours. On this head, Mr. Lloyd, in his Optics, says — ' In their refractive power, the aqueous and vitreous humours differ very little from that of water. The refractive index of the aqueous humour is 1.337, and that of the vitreous humour 1.339; that of water being 1.336. The refractive power of the crystalline is greater, its mean refracting index being 1.384. The density of the crystal- line, however, is not uniform, but increases gradually from the outside to the centre. This increase of density serves to correct the aberration by increasing the convergence of the central rays more than that of the extreme parts of the pencil.' Dr. Brewster, in his treatise on Optics, says — 'I have found the following to be the refractive powers of the different humours of the eye, the ray of light being incident upon them from the eye : aqueous humour 1.336; crystalline, surface 1.3767, centre 1.3990, ON CATARACT. 11 mean 1.3839; vitreous humour 1.3394. But as the rays refracted by the aqueous humour pass into the crystalline, and those from the crystalline into the vitreous humour, the indices of refraction of the separating surface of these humours will be, from the aqueous humour to the outer coat of the crystalline 1.0466, from the aqueous humour to the crystalline, using the mean index, 1.0353, from the vitreous to the outer coat of the crystalline 1.0445, from the vitreous to the crystalline, using the mean index, 1.0332.' Dr. Young says — ' On the whole, it is probable that the refractive power of the centre of the human crystalline, in its living state, is to that of water nearly as 18 to 7 ; that the water imbibed after death reduces it to the ratio of 21 to 20 i but that on account of the unequable density, its effect in the eye is equivalent to a refraction of 14 to 13 for its whole size.' Respecting the chemical composition of the lens, Berzc- lius observes, that ' the liquid in its cells is more concen- trated than any other in the body. It is completely dia- phanous and colourless, holding in solution a particular animal matter belonging evidently to the class of albumin- ous substances, but differing from fibrine in not coagulating spontaneously, and from albumen, inasmu;:h as the con- centrated solution, instead of becoming a coherent mass on the application of heat, becomes granulated exactly as the colouring matter of the blood when coagulated, from which it only differs in the absence of colour. All those chemical properties are the same as those of the colouring matter of the blood. The following are the principles of which the lens is composed ; peculiar coaguable albuminous matter 35.9, alcoholic extract with salts, 2.4, watery extract with traces of salts 1.3, membrane, forming the cells 2.4, water 58.0.' From the preceding observations it might reasonably be supposed that the lens is composed of a homogeneous ma- terial, such as albumen or gelatine, more consolidated in the centre than at the circumference ; but this Is not the case ; on the contrary, it exhibits as much of elaborate organization as any other structure in the animal economy. 12 ON CATARACT. It consists of an outer case or capsule, so totally different from the solid body contained within it, that they must be separately investigated and described. The body of the lens, it has been already stated, consists of certain saline and animal ingredients combined with more than their weight of water, and when perfectly transparent presents the appearance of a tenacious unorsranized mass ; but when rendered opaque by disease, loss of vitality, heat, or im- mersion in certain fluids, its intimate structure becomes visible. If the lens with the capsule attached to the hyaloid membrane be removed from the eye and placed in water, the following day it is found slightly opaque or opaline, and split into several portions by fissures extending from the centre to the circumference, as seen in fig. 2. This appearance is rendered still more obvious by immersion in spirit, or the addition of a few drops of acid to the water. If a lens thus circumstanced be allowed to remain some days in water, it continues to expand and unfold itself, and if delicately touched and opened by the point of a needle, and carefully transferred to spirit, and as it hardens is still more unravelled by dissection, it ultimately presents a remarkable fibrous or tufted appearance, as represented in the figure below, drawn by me some years ago from a preparation of the lens of a fish thus treated (the Lophius piscatorius). The three annexed figures represent the structure of the lens above alluded to : -4 is the human crystalline in its natural state ; B, the same split up into its component plates ; and C, unravelled in the fish. Fig. 2. c n. This very remarkable structure of the body of the lens ON CATARACT. 13 appears to have been first accurately described by Leeuwen- hoek, subsequently by Dr. Young, and still more recently by Sir David Brewster. Leeuwenhoek says — ' It may be compared to a small globe or sphere, made up of thin pieces of paper laid one on another, and supposing each paper to be composed of particles or lines placed somewhat in the position of the meridian lines on a globe, extending from one pole to the other.' Again, he says — ' With regard to the before -mentioned scales or coats, I found them so exceedingly thin, that, measuring them by my eye, I must say that there were more than two thousand of them lying one upon another : and lastly, I saw that each of these coats or scales was formed of filaments or threads placed in regular order, side by side, each coat being the thick- ness of one such filament.' The peculiar arrangement of these fibres he describes as follows: — ' Hence we may col- lect how excessively thin these filaments are ; and we shall be struck with admiration in viewing the wonderful man- ner they take their course, not in a regular circle round the ball of the crystalline humour, as I first thought, but by three different circuits proceeding from a point, which point I will call their axis or centre. They do not on the other side of the sphere approach each other in a centre, but return in a short or sudden turn or bend, where they are the shortest,, so that the filaments of which each coat is composed have not in reality any termination or end.' Dr. Young differs from Leeuwenhoek as to the arrange- ment of the fibres and other particulars, and in his last paper corrects the description given by himself in a former one ; he says — ' The number of radiations (of the fibres) is of little consequence ; but I find that in the human crystalline there are ten on each side, not three, as I once from a hasty observation concluded. In quadrupeds the fibres at their angular meeting are certainly not continued as Leeuwenhoek imagined.' Sir David Brewster says that the direction of the fibres is different in different animals ; the simplest arrangement being that of birds, and the cod, haddock, and several other 14 ON CATARACT. fishes. In it the fibres, like the meridians of a globe, converge to two opposite points of a spheroidal or lenticular solid, as in the an- nexed figure. The second or next simplest structure he detected in the sal- mon, shark, trout, and other fishes ; as well as in the hare, rabbit, and porpoise amon^ the mammalia ; and in the alligator, gecko, and others among reptiles. Such lenses have two septa at each pole, as in the annexed figure. Fig. 4. The third or more complex structure exists in mammalia in general, ' in which three septa di- verge from each pole of the lens, at angles of 120 deg., the septa of the posterior surface bisecting the angles formed by the septa of the anterior surface,' as in the annexed figure. Fig. 5. The mode in which these fibres are laterally united to each other is equally curious. Sir David Brewster says that he ascertained this in looking at a bright light through a thin lamina of the lens of a cod, when he observed two faint and broad prismatic images, situated in a line ex- actly perpendicular to that which joined the common coloured images. Their angular distance from the central image was nearly five times greater than that of the first ON CATARACT. 15 ordinary prismatic images, and no doubt whatsoever could be entertained that they were owing to a number of minute lines perpendicular to the direction of the fibres, and whose distance did not exceed the 12-300dth of an inch. Fig. 6. Upon applying a good micro- scope to a well- prepared lamina, the two fibres were found united by a series of teeth exactly like those of rack-work, the project- ing teeth of one fibre entering into the hollows between the teeth of the adjacent one, as in fig. 6. I have said that the lens consists of an outer case or cap- sule totally different from the solid body contained within it. This capsule is strong, elastic, and perfectly transpa- rent. In the paper to which I have alluded in the Medico- Chirurgical Transactions, I gave the following detailed description of its nature and properties : — * The real na- ture of the capsule of the lens has not, I think, been suflS- ciently attended to ; its thickness, strength, and elasticity have certainly been noticed, but have not attracted that attention which a fact so interesting, both in a physiological and pathological point of view, deserves. That its struc- ture is cartilaginous, I should conclude — first, from its elasticity, which causes it to assume a peculiar appearance when the lens has been removed, not falling loose into folds as other membranes, but coiled in different directions : or if the lens be removed by opening the capsule behind, and withdrawing it through the vitreous humour, allowing the water in which the part is immersed to replace the lens, the capsule preserves in a great degree its original form, especially in the eye of the fish ; secondly, from the den- sity and firmness of its texture, which may be ascertained by attempting to wound it by a cataract needle, by cutting it upon a solid body, or compressing it between the teeth ; thirdly, from its permanent transparency, which it does ON CATARACT. not lose except on the application of very strong acid or boiling wat€r, and then only in a slight degree ; macera- tion in water for some months, or immersion in spirit of strength suflficient to preserve anatomical preparations, having little or no effect upon it. If the lens be removed from the eye of a fish dressed for the table, the capsule may be raised by the point of a pin, and be still found almost perfectly transparent. This combination of density and transparency gives the capsule a peculiar sparkling appear- ance in water, in consequence of the reflection of light from its surface, resembling a portion of thin glass which had assumed an irregular form while soft ; this sparkling I consider very characteristic of this structure. The pro- perties just enumerated appear to me to distinguish it from every other texture but cartilage ; still, however, it may be said that cartilage is not transparent, but even the car- tilage of the joints is semitransparent, and if divided into very thin portions, is sufficiently pellucid to permit the perception of dark objects placed behind it, and we obtain it almost perfectly transparent where it gives form to the globe of the eye, as in the sclerotic of birds and fishes. If the soft consistence, almost approaching to fluidity, of the external part of the lens, be considered, the necessity of a capsule capable itself of preserving a determinate form is obvious. If the lens were enclosed in a capsule such as that which envelopes the vitreous humour, its surface could not be expected to present the necessary regular and per- manent curvature; nor could we expect that if the form of the lens were changed, it could be restored without this provision of an elastic capsule.' The capsule is liable to become opaque and constitute cataract, as the body of the lens is. These capsular cata- racts are easily distinguished from the lenticular. They never present the stellated appearance frequently observed when the texture of the opaque lens opens in the capsule, as it does when macerated in water, nor the uniform horny or the milky blue appearance of common lenticular cata- ract. The opacity in capsular cataract exists in the shape of irregular dots or patches, of an opaque paper-white ap- ON CATARACT. 17 pearance, and when touched with the needle are found hard and elastic, like indurated cartilage, the spaces between the specks of opacity frequently remaining perfectly trans- parent. It appears to be generally assumed by writers on anatomy that a watery fluid is interposed between the body of the lens and its capsule, from an incidental observation of Morgagniwhen discussing the difference in density between the surface and centre of the lens ; hence it has been called the aqua Morgagni. The observation of this celebrated anatomist, in his Adversaria Anatomica, which has led to the universal adoption of this notion, is, however, merely that upon opening the capsule he had frequently found a fluid to escape. ' Deinde eadem tunica in vitulis etiam, bobusque sive recens, sive non ita recens occisis perforata, pluries animadverti, illico humorem quendam aqueum prodire : quod et in homine observare visus sum, atque adeo credidi, hujus humoris secretione prohibita, crystalli- num siccum, et opacum fieri fere ut in extracto exsiccato- que crystallino contingit. ' He does not, however, subse- quently dwell upon or insist upon the point. I do not believe that any such fluid exists in a natural state, but that its accumulation is a consequence of loss of vitality ; the water combined with the solid parts of the lens escap- ing to the surface and being detained by the capsule, as occurs in the pericardium and other parts of the body. In the eyes of sheep and oxen, when examined a few hours after death, not a trace of any such fluid can be detected, but after about twenty- four hours it is found in considerable quantity. In the human eye a fluid sometimes accumu- lates in the capsule, constituting a particular form of cata- ract, which presses against the iris, and almost touches the cornea ; but such eyes are, I believe, always unsound. From this erroneous notion of an interposed fluid between the lens and its capsule has arisen the adoption of an un- sustained and improbable conclusion, that the lens has no vital connexion with its capsule, and consequently must be produced and preserved by some process analogous to secretion. Respecting this matter I have observed, in the 2 B iO ON CATARACT. paper above alluded to : * The lens has been considered by some as having no connexion with its capsule, and con- sequently that its formation and growth is accomplished without the assistance of vessels ; such a notion is so com- pletely at variance with the known laws of the animal eco- nomy, that we are justified in rejecting it, unless supported by unquestionable proof. The only reasons which have been advanced in support of this conclusion are, the failure of attempts to inject its vessels, and the ease with which it may be separated from its capsule when that membrane is opened. These reasons are far from being satisfactory ; it does not necessarily follow that parts do not contain ves- sels, because we cannot inject them ; we frequently fail when there can be no doubt of their existence, especially where they do not carry red blood. I have not myself succeeded in injecting the vessels of the lens, but I have not repeated the trial so often as to make me despair of accomplishing it, more especially as Albinus, an anatomist whose accuracy is universally acknowledged, asserts, that after a successful injection of the capsule of the lens, he could see a vessel passing into the centre of the lens itself. Lobe, who was his pupil, bears testimony to this. The assertion that the lens is not connected with its capsule, I think I can show to be incorrect ; it has been made from want of care in pursuing the investigation, and from a notion that a fluid exists throughout between the lens and its capsule. "When the capsule is opened, its elasticity causes it to separate from the lens ; especially if the eye be examined some days after death, or has been kept in water, as then the lens swells, and often even bursts the capsule and protrudes through the opening, by which the connexion is destroyed. I have, however, satisfied myself that the lens is connected with its capsule (and that con- nexion by no means slight) by the following method. I remove the cornea and iris from an eye, within a few hours after death, and place it in water, then with a pair of sharp- pointed scissors I divide the capsule all round at the cir- cumference of the lens, taking care that the division is made behind the anterior convexitv, so that the lens can- ON CATARACT. 19 not be retained by any portion of the capsule supporting it in front. I next invert the eye, holding it by the optic nerve, when I find that the lens cannot be displaced by agitation, if the eye be sufficiently fresh. In the eye of a young man about six hours dead, I found that, on push- ing a cataract needle into the lens, after the anterior part of the capsule had been removed, I could raise the eye from the bottom of the vessel, and even halfway out of the water, by the connexion between the lens and its capsule. It afterwards required considerable force to separate them, by passing the needle beneath the lens, and raising it from its situation. I believe those who have been in the habit of performing the operation of extraction, have occasionally encountered considerable difficulty in detaching the lens from its situation after the capsule had been freely opened, this difficulty I consider fairly referrible to the natural connexion just noticed.' When the lens enclosed in its capsule is detached from the hyaloid membrane, the con- nexion between it and the capsule is destroyed by the handling, and in consequence, it moves freely within that covering, affording to those who believe that there is no union between the two surfaces fallacious evidence in sup- port of that opinion, which, if not sustained by better proof, should be abandoned. Dr. Young insists upon the existence of the natural connexion by vessels and even by nerves between the lens and its capsule : he says — ' The capsule adheres to the ciliary substance, and the lens to the capsule, principally in two or three points ; but I con- fess I have not been able to observe that these points are exactly opposite to the trunks of nerves ; so that probably the adhesion is chiefly caused by those vessels which are sometimes seen passing to the capsule in injected eyes. We may, however, discover ramifications from some of these points upon and within the substance of the lens, generally following a direction near to that of the fibres, and sometimes proceeding from a point opposite to one of the radiating lines of the same surface. But the principal vessels of the lens appear to be derived from the central artery, by two or three branches at some little distance '20 ox CATARACT. from the posterior vortex, which I conceive to be the cause of the frequent adhesion of a portion of a cataract to the capsule about this point ; they follow nearly the course of the radiations and then of the fibres j but there is often a superficial subdivision of one of the radii at the spot where one of them enters.' The great size of the vessels distri- buted on the back of the capsule in the fcEtus strengthens the conclusion that the lens is furnished with vessels as the rest of the body. When the eye of a foetus of seven or eight months is finely injected, a branch from the central artery of the retina is filled and may be traced through the centre of the vitreous humour to the back of the capsule, where it ramifies in a remarkably beautiful manner, assum- ing, according to Sommerring, a stellated or radiating ar- rangement. Zinn declares that he found branches from this vessel penetrating the lens : ' Optime autem placet observatio arteriolae lentis, in oculo infantis, cujus vasa cera optime erant repleta, summa voluptate mihi visas, quam prope marginem ad convexitat^m posteriorem dila- tam, duobus ramulis perforata capsula in ipsam substan- tiam lentis profunde se immergentem cortissime conspexi.' He also quotes the authority of Ruysch, Moeller, Albinus, and Winslow, as favouring the same view. Against such authority I find that of the French systematic writer Bichat advanced j but on such a point his opinion is of little value." With respect to the nutrition of the lens and the nature of its connexion with the capsule, it is necessary to state that observers entitled to confidence deny the existence of vessels in its structure, and consider that it grows by im- bibing new matter from its capsule. Dr. Muller of Berlin says that the capsule of the lens is its matrix, which seems to secrete the layers of the lens from its inner surface, but that this has not been ascertained with certainty. Mr. Toynbee, in a valuable paper printed in the second part of the Philosophical Transactions for 1841, says that " the ON CATARACT. 21 mode of nutrition of the crystalline lens may be explained by supposing that the nutrient fluid is received by the cells and conducted to the lens, through which it is dif- fused ;" it being believed that cells are either interspersed, among the fibres, or that the fibres are composed of them. Notwithstanding this, I cannot admit that it is proved that the lens, or the cornea and vitreous humour, are des- titute of vessels. I do not mean to deny that nutrition may be and is effected, as in the simpler forms of animal and vegetable life, without the aid of tubular vessels, and therefore cannot deny that the structures here alluded to may be so nourished ; but the question is not yet settled. Microscopic observations of fluids which are easily dif- fused, separated, and diluted, may be relied upon ; but those on organized solids not admitting of subdivision without destruction, cannot be received with so much con- fidence. Microscopic observers have, perhaps, been going a little too fast, and must allow us a little breathing time before we can accept all that is offered by them ; and the more especially because the instrument has been laid hold of, for the purpose of display, by ignorant persons totally unacquainted with its use, and incapable of making correct observations. The question, however, of the vascularity of these structures, is not perhaps of so much practical importance, seeing that, whether vascular or not, they undergo the same changes, both in health and disease, as vascular parts do. The cornea heals by first intention, ulcerates, granulates, and cicatrizes, and the lens becomes opaque, softens, hardens, and even is partially converted into a calcareous structure. These changes I shall have to notice presently, when I come to consider the great variety of forms of cataract, and the other alterations of the lens caused by age, inflammatory action, and injury. 22 ON CATARACT. ON CATARACT OR OPACITIES OF THE LENS. Having endeavoured to explain the form, properties, organization, and vitality of the lens, I have now to con- sider the changes it undergoes from age, inflammation, im- perfect or irregular nutrition, and injury. Writers on diseases of the eye enumerate a great variety of cataracts, applying different names to every different appearance which these opacities assume, as they have done with re- spect to opacities of the cornea. This, however, is of little use, causes unnecessary trouble and confusion, and diverts the mind from the investigation of the real cause of these appearances. It is much better to consider the real nature of these changes, and to explain the state of structure be- longing to them. The crystalline lens does not become opaque from a great number of different diseases affecting it ; it is only the forms of opacity which are so numerous. In the first place, it must be obvious that the lens being composed of two structures so different in every respect as the capsule and the body of it, and that both these being liable to become opaque, there must, necessarily be at least two very different forms of opacity, and hence the division of cataracts into capsular and lenticular. The lenticular is to be first noticed. From what has already been said respecting the change which the lens undergoes in advanced life, it is clear that it is liable to become still more changed from the same cause, and experience has proved that such is the case. In the great majority, it not only becomes much more flat, and hence long sight requiring convex glasses, but also coloured; acquiringanamber tint, although previously clear as water. In still more advanced life it ON CATARACT. 23 also loses its perfect transparency, and becomes slightl}- opaque or milky, although not so much so as to impair vision materially. This I conclude from the appearance it presents on dissection, and when seen in the living sub- ject by causing the light to be reflected from it, especially when the pupil is dilated with belladonna. When this colour and loss of transparency increases still more, vision becomes impaired and the opacity becomes visible in the pupil, constituting the lenticular cataract of advanced life ; one of the most common forms of the disease met with. But the lens at this period becomes not only coloured and milky or opaline, but also much firmer in consistence, and hence the hardness of this species of cataract. The appear- ance, however, of the hard lenticular cataract of advanced life varies very much. It generally resembles a piece of muddy amber, or still more, common horn, such as is used for lanterns ; but is sometimes so brown that it cannot be seen behind the pupil unless a strong light be thrown on it obliquely, and hence probably the origin of the notion that there is a black cataract. The hard lenticular cataract frequently also presents the appearance which has been denominated glaucoma, a greenish shining hue not easily described, and scarcely to be represented on paper. This semitransparent, amber, horny or opaline state of the lens is not, however, by any means the uniform appear- ance of the lenticular cataract of advanced life ; on the contrary, the cataract of old persons is often of an opaque white, or even a bluish white, like the lenticular cataract of early life, or it may be irregularly clouded, stellated, or combined with capsular cataract. The stellated opacity of the lens which sometimes occurs in the lenticular cataract of old age, but more frequently in that of earlier life, it is necessary to consider distinctly, because it is the result of additional disorganization, and 24 ON CATARACT. indicates a softer state of the lens, rendering it more easily broken up and more fit to be absorbed. I have already shown that from its fibrous structure, the lens splits up into segments when immersed in water or other fluid, and from whatever cause it may be, a similar change sometimes takes place during life, constituting this stellated opacity or cata- ract. There is no difficulty in recognizing this state, or of perceiving that it depends upon a yielding of the natural structure, and that it is accompanied by a corresponding softness and looseness of texture favourable to division with the needle. This splitting up of the lens into segments, from the centre to the circumference, may be produced by removing it from the eye of a sheep or other animal enclosed in its capsule, and leaving it in water for a day or two. Thus treated it becomes opaque, while the bars of the stel- lated breach on its anterior surface are transparent, being in fact filled with water. Now, if we are to give a name to these different states, we may call the uniform amber or horny opacity, the hard amber or horny cataract of advanced life ; and if marked by bars radiating from the centre to the circumference, we may add that it is stellated. There is, however, another kind of opacity which occurs at an advanced period of life which presents a more or less stellated arrangement. This is produced by delicate slen- der white streaks which run in the direction of the fibres, and therefore from centre to circumference, the rest of the lens retaining its transparency, or being only slightly opaque ; so much so, that persons with this k«nd of cata- ract often enjoy useful vision. These white streaks or veins do not, however, always or even frequently assume the stellated arrangement, but run as single streaks across the whole face of the lens, with perhaps one or two other streaks diverging from it about the centre. It is a remark- able, distinct, and easily recognized opacity, although it ON CATARACT. 25 often escapes notice, especially where the pupil is small ; and is obviously very different in its nature from the hard, amber, or horny cataract just described. It is also remark- able for the slowness of its progress to perfect opacity, often existing for many years before it causes blindness and re- quires operation. Such cataracts are not, perhaps, harder than a healthy lens at the same period of life, and the streaks of opacity are obviously not slits or spaces formed by the receding of the fibres from each other, but an in. duration and consequent opacity of a certain number of them, the rest remaining transparent. I am surprised that this form of cataract has not been more particularly described and distinguished from the common hard stellated cataract, especially considering the anxiety shown to mul- tiply varieties and vary names, for there can be no doubt of its being of a peculiar nature. It is it Mr. Mackenzie alludes to when he says — " It is not an uncommon appear- ance to see opaque strice stretching from the circumference of the lens a short way into its substance ;" and Mr. Law- rence notices it as a radiated cataract having the rays com- mencing at the circumference instead of at the centre, as in the more common or softer stellate cataract. *' Lenti- cular cataracts (he says) are sometimes radiated, the opacity appearing in streaks or radii, with the intervals compara- tively transparent. Those radii generally begin in the cir- cumference of the lens — a circumstance which forms a striking contrast to the former species, in which the opacity first appears in the centre. In the ordinary state of the pupil we can hardly see the radiated opacity, because the centre remains transparent ; perhaps a small white streak or two may be distinguished : it is not, however, till we have dilated the pupil by belladonna that we detect the opaque streaks in the circumference of the lens." I sometimes, however, find these opaque striae in the lens without the 26 ox CATARACT. marginal radii. It is probably to this form of cataract Mr, Bowman alludes in the following passages* : — "In the commencing cataract of middle or declining age, we not uncommonly find the posterior surface of the lens first affected, so that we look through the transparent lens upon an obviously concave opacity. This opacity sometimes, and indeed generally, encroaches from the mar- gin in distinct streaks of irregular thickness, length, num- ber, and distance apart ; and we usually find that, when the pupil is widely dilated by belladonna, some at least of these streaks are traceable round the margin for some way over the anterior surface. So long as small portions of the hinder surface of the lens remain clear, the body and front being also clear, it is surprising how much visual power may remain. At a subsequent period, the centre of the lens begins to be cloudy, and then the progress towards blindness is more rapid. Now I can entertain no doubt that the streaks in these cases are sets or bundles of the superficial layer of lenticular fibres, reduced to a state of opacity by some nutritional change. There seems to be a disposition in the fibres of the lens to become opaque in their entire length when once they are morbidly altered at a single point : and hence the linear figure of the opacity. The opacity probably commences in the middle part of the fibres near the margin of the lens ; and the arrangement of the fibres would account for the different length of the streaks, some approaching nearer than others to the central point on the surface. In another variety of opacity in adults, there are streaks visible, either on the anterior or posterior surface, before the nucleus manifests any tendency towards dulness, but instead of converging from the border of the lens, they rather diverge from the central point. These streaks are also irregular in number and direction ; and it has never occurred to me to distinguish in them any exact representa- • Lectures on the Parts concerned in the Operations of the Eye. By W. Bowman, F.B.S. London. 1849. ON CATARACT. 27 tion of the edges of the mesial planes as they are seen on the surface of the prepared lens ; never, certainly, any trillnear figure. But a glance at the representation above given of the complex arrangement of the mesial planes in the adult human lens, will suffice to explain why they are rarely seen in such opacities. In the healthy lens they are in reality too near together, and too irregular, to be detected without a glass. The triple divergence from the axis can, even then, only be recognized for a short distance, beyond which the planes seem to diverge and branch without any attempt at geometrical precision. We cannot, therefore, wonder that an opacity, spreading from the centre of the surface of the lens, and which consists of broad, ill-shapen streaks, should fail to disclose the radiation of the mesial planes : although it seems highly probable that its seat is, primarily and essentially, rather in the edges of those planes than in the fibres themselves. In the lenticular cataract of adults, the glistening, silky, fibrillation of the lens may be often seen ; but you will fail, even in the best-marked of these cases, to discover, with the naked eye, anything like regularity in the mode in which the fibres pass off from the central region. Be- fore becoming acquainted with the complex arrangement of the planes of the human lens, I could not satisfy myself why the triple line of the mammalian lens should be un- seen ; but the actual complexity is a sufficient reason. It explains, too, the appearances of many cases of opacity of the body of the lens, where the fibrous texture is in general obvious enough, but where, towards the centre, an amor- phous, indefinable obscurity exists." Of the hard lenticular cataracts of advanced life, we have then the amber or horny, the stellate, and the striated, but these are not the only varieties. Cataracts in old persons are often white and very opaque with- out any radii^ presenting a muddy cream-coloured or even a bluish milky uniform surface, behind the pupil, and such often have an opaline lustre from a hard amber cen- 28 ox CATARACT, tral nucleus reflecting the light through a semitransparent superficial stratum. These cataracts appear so soft and pulpy that they often tempt persons to operate on them with the needle to cause their solution and absorption, but they are almost always hard in the centre, leaving a small nucleus undissolved for a very long time in the posterior chamber after operation, moving up and down with the motions of the eye. Besides these four distinct forms of hard lenticular cataract of advanced life, the amber, stel- lated, striated, and white or opaline, there are many inter- mediate varieties which might be enumerated under differ- ent names, and also many rarer varieties of the same species presenting such peculiarities that they might be described very properly as peculiar products of disease ; but my ob- ject is to direct attention to the usual forms with a view to ascertain their consistence and solubility for the purpose of determining which operation should be chosen for their removal. It should, however, be observed that all these lenticular cataracts are more transparent and softer at the circumference, because the lens in health is there thinner and softer, and consequently, that when the pupil is dilated with belladonna, they admit more light and appear less opaque at the margin, except indeed it be the striated cataracts which are often more opaque at the circumference. Lenticular cataracts are not found in persons advanced in life only, they occur at every period from infancy to old age, but in early life they are very different in form, consistence, and colour. As the hard amber cataract is that which occurs most frequently in aged people, the light -blue or milky one generally constitutes the disease in younger persons. It is also much softer, frequently in- deed softer than the lens is in its natural or healthy state at the same period of life ; and instead of being shrunk or flat, it is generally enlarged or swelled. Therefore, as ON CATARACT. 29 has been said, the hard amber- coloured shrunk lens most commonly forms the cataract of advanced life, while the soft milky-blue prominent one is found most frequently in early life. There are, however, many varieties and modi- fications of the disease at this period, as there are at the other. Of these varieties, that which most frequently occurs is the starred or stellated one already noticed as a variety of the harder cataract of advanced life : the lens, in fact, being not only opaque, but so disorganized or changed in structure, that it has split up on its surface and exhibits deep fissures radiating from the centre to the cir- cumference. The colour, however, instead of being a dirty-white, as in old age, is a milky-blue, and the fissures are of a lighter tint, as if filled by water, which they pro- bably really are, the whole being so soft and pulpy that there is no diflSculty in completely mashing it up with the needle in operation. A variety of the striated cataract described as occurring in advanced life, is also often found in early life, the striae commencing at the circumference and converging to the centre, and not being open fissures but opaque veins with transparent intervals between them. Sometimes a defined circular white spot, very opaque, is found occupying the centre of a transparent lens, with one or more equally opaque thick bars or veins radiating from it toward the circumference. In using the term vein, I mean veins such as exist in minerals. This central opacity with dense radiating striae, is generally, but not always, accompanied by an equally dense defined opacity of the capsule of smaller size, easily distinguished by its chalky whiteness and cartilaginous appearance, con- stituting a variety of capsulo-lenticular cataract. This dense opacity of the lens has not, however, always the bars or striae radiating to the edge, but exists alone in a lens perfectly transparent to the circumference, admitting of 2 c 30 ON CATARACT. very useful vision when the pupil is dilated with belladonna. Such are very slow in progress, sometimes, in fact, being permanent, and undergoing little or no change for many years, if not indeed for life, and they are often congenital, but I think not always, for I have sometimes found them in persons somewhat advanced in life who insisted upon it that they had always had good sight until a comparatively recent period. The late Mr. Tyrrel, in his book on Diseases of the Eye, describes the striated cataract, but does not, I think, appear to have distinguished it from the stellated. He says, alluding to the distortion or multiplication of objects in incipient cataract, " when these modifications of symptoms have presented themselves, I have found that the opacity of the lens has not been confined merely to the centre, but that one or two, or several, opaque radii have existed, passing from the centre to the circumference of the body." (Vol. ii., p. 355.) And again (p. 363), '• In rare instances, when cataract commences from the circumfer- ence, and proceeds by radii toward the centre, these radii are at first confined to the posterior hemisphere of the lens. This opinion, however, is equally erroneous with that before adverted to respecting the anterior portion of the lens, as I have had opportunity of ascertaining by watching the progress of such cases, and subsequently ex- tracting the cataracts." Mr. Saunders in his treatise (p. 133., pi. iv., fig. 3,) says : — " There is a form of the con- genital cataract in which the centre of the lens is opaque and its circumference perfectly transparent. In these cases the lens remains of its natural size as long as its cir- cumference preserves its transparency, which, if undis- turbed, it will do for many years." Fig. 3, referred to, shows, he says, '• a lens of which the centre is opaque and the circumference is transparent, with the exception of three opaque radiated lines;' and it shows also a small ON CATARACT. 31 defined opacity of the capsule over that of the lens, but smaller than it. I have now in this paragraph shown, that of the lenticular cataract of earlier life there are four varieties : the uniform light-blue or milky ; the stellated, or split from centre to circumference j the radiated, with veins from the edge toward the centre ; and that with an opacity in the centre, with or without white bars or thick veins running to the edge. But these are not all, for sometimes the opacity is irregularly clouded, as if the original fibrous structure of the lens was destroyed, and the part converted into a grumous mass, as it appears some weeks after having been freely broken up by the needle. Mr. Wardrop, in his essays on the Morbid Anatomy of the Eye (vol. ii., p. 81), says, alluding to this variety: — *' Sometimes they are clouded in difierent parts, having the appearance of a flake of snow ;" and Mr. Tyrrel (vol. ii., p. 364) says: — " Sometimes the surface of the opaque body appears flocculent, like the surface of a recently broken piece of spermaceti." These cataracts are very soft, and are speedily absorbed after breaking up. If they are to have a name, they may be called flocculent. There is yet another variety which I have often seen and operated on. It is a very light-blue cataract, the colour of milk and water, which evidently contains a quantity of fluid between the lens and its capsule, for it is quite prominent, pressing upon the iris so as to cause dilatation of the pupil, and almost, if not all out, touching the back of the cornea. This can be distinctly seen by looking at the eye in profile, or sideways, the patient facing the light. Before I was aware of the existence of this form of cataract, I was much surprised to find that in operating on it I did not break it up and scatter the pulp into the anterior chamber, as I do in very soft cataracts, but that the more I worked at it the less it moved. In fact, I had been all the time 32 OS CATARACT. moving the needle about within the capsule, bat when I saw how it was circumstanced I brought (he instrument up to the back of the cornea and tore open the capsule, when it was immediately mixed up with the aqueous humour as usual. Whether or not it is this variety which authors allude to under the name of Morgagnian cataract I cannot tell, because they seem to differ in their descriptions of it. Mr. Mackenzie, in his work on Diseases of the Eye, ap- pears to describe it under this title. He says: — "The effusion of an opaque fluid between the lens and its cap- sule forms one of the rarest kinds of cataract. It is gene* rally followed by dissolution of the lens, and not unfre- quently by capsular opacity. So long as the cataract con- sists in a mere effusion between the capsule and lens, it presents a cloudy appearance, as if formed of milk and water imperfectly mixed. It is stated that if the eyeball is repeatedly rubbed with the finger through the medium of the eyelid, the clouds of opacity change their outline and position ; and sometimes they do so merely on quick motion of the eye from side to side. The capsule is dis- tended in cases of Morgagnian cataract, and pressing against the iris obliterates the posterior chamber and im- pedes the motions of the pupil. When the disease is purely Morgagnian vision is sometimes but slightly im- paired, small objects escaping the observation of the pa- tient, especially after the eye has been rubbed or moved, but after the lens dissolves, the sight is limited to the per- ception of light and shade." Mr. Lawrence says: — •* Opacity of the fluid situated between the lens and its capsule has been called cataracta Morgagniajia ; but I doubt its separate existence. How can we determine that the fluid is opaque and the lens transparent ? Can we suppose that this fluid is opaque and the lens remains trans- parent? I think, therefore, that in a practical consider- ON CATARACT. 33 ation of the subject this kind of cataract might be safely omitted." Beer speaks of such a cataract occurring sud- denly in consequence of exposure of the eye to acid va- pours, and adds observations which render it doubtful whether he understood the nature of the disease at all. In the cataract to which I allude, I do not think that it is the fluid which is opaque, but the lens behind it, which is, I think, a common soft cataract. Mr. Mackenzie adds, that a •' pure Morgagnian cataract is not to be touched in the way of operation." The cataract I have been alluding to I frequently operate on with success. Notwithstanding the varieties of lenticular cataract, both of advanced and early life, above enumerated, many other forms of disorganization of this body might be described. I have seen the lens of a beautiful pale opaque green after general inflammation of the eye, and other curious appear- ances of it are occasionally met with ; but the greatest amount of disorganization is found in congenital cataracts, and where the eye has been destroyed by the inflammation commonly called iritis, but which should be called ophthal- mia. When this happens the pupil is generally adherent to a white, thickened, hard, opaque capsule, within which is a shrunk, friable, white fragment, bearing no resem- blance in structure to the original lens, and in congenital cataract, as shall be noticed presently, similar or equally great disorganization is observed. These shreds of lens are, I believe, what are called siliquose cataracts. That the lens sometimes, but very rarely, has earthy matter de- posited in its structure, most probably phosphate of lime, is an admitted fact, and one of interest in a physiological point of view, when it is recollected that the nutrition of this part has been attributed to a secreting process rather than to the usual growth by vascular ramification. Mr. Wardrop records an example of it, and I have myself seen 34 ON CATARACT. Streaks of white earthy material among the fibres of the lens in horses' eyes destroyed by inflammation. Mr. Wardrop describes it as "ossification of the lens," and states that " on dividing the crystalline lens its central portion was found converted into hard bone. The external laminae of the lens were soft, but those nearer the centre became more consolidated, the central portion itself being of a deep brown colour, perfectly osseous, and exhibiting a laminated structure." And again, in his description of a plate of it : — " The ossification is seen commencing in the centre of the lens, and extending towards its circumfer- ence in the form of concentric bony laminae. The central portion was a dark brown coloured and hard bone ; the exterior laminae were of a paler colour, and more friable." This example, thus authenticated, is of great value, be- cause although ossifications of the capsule of the lens have been met with occasionally, conversion of the body of the lens into bone, or an earthy solid resembling it, is of extreme rarity. The lens has been found sometimes, although rarely, in congenital cataract converted into a white milky fluid. Mr. Saunders records two, in which opaque cap- sules were found filled with such material. In fact, there seems to be no end to the variety in form, consistence, and colour, observed in cataracts of long standing, especially when congenital, or caused by inflammation or injury, but it would be tedious and superfluous to enumerate all these under different names. In alluding to the causes of cata- ract and the possibility of its spontaneous cure, it will be necessary to call attention to cataract from wounds or other injuries of the eye. Here it is only necessary to say, that such cataracts are of a bluish-white appearance, and irregular flocculent composition ; sometimes, when the wound in the capsule is very small, presenting the stellate form ; sometimes, when the rent is larger, projecting in ON CATARACT. 35 the shape of a white fleecy mass through the pupil into the anterior chamber ; and sometimes, when the whole face of the capsule is torn open, swelling out so as to fill up the whole anterior chamber up to the very back of the cornea. OP CAPSULAR CATARACTS. I HAVE said above that " the lens being composed of two structures so different in every respect as its capsule and body, and that both these being liable to become opaque, there must necessarily be at least two very different forms of opacity, and hence the division of cataracts into capsular and lenticular." I have now to treat of the capsular. After what has been stated respecting the nature and structure of the capsule of the lens, it becomes obvious that opacities of it must be very different from those of the lens itself I have said the capsule is composed of a hard, elastic, solid mate- rial, and have expressed my belief that it is nothing else but transparent cartilage. Of this I entertain no doubt ; and the examination of capsular cataracts has strengthened this conviction. When the capsule has become opaque, it seems in fact to have merely degenerated into cartilage of a coarser structure, and consequently to have lost its characteristic delicate and perfect transparency ; while it has at the same time become thickened and harder. Such cataracts necessarily present appearances totally different from those observed in the lenticular form. There being no fibrous structure arranged from centre to circumference, there is therefore no stellated or striated opacity, but either one patch, more or less uniform, or a number of small patches, streaks, or dots, sometimes presenting a veined or marble appearance, sometimes an arborescent or meandering out- line. This remarkable irregularity in shape must at all 36 ox CATARACT. times serve to distinguish the capsular from the lenticular cataract. The whiteness or complete opacity of capsular cataracts is as characteristic of the disease as the irregular mottled, dotted, or marbled appearance. Sometimes, it is true, the opacity is not so dense, but in general it is as white and compact as paper, resembling the membrane within the external shell of an egg, and being either a uniform patch or an irregular one, with intervals or small spaces less opaque pervading it. The surface sometimes, if not gene- rally, loses that perfect smoothness and polish which dis- tinguishes the capsule in its healthy state, and becomes rugged or undulating ; while at the same time it is so hard and tough that great force is required to tear it. It is even sometimes converted into a calcareous layer, consti- tuting what is called ossification of the capsule. All these qualities of capsular cataracts are worthy of attention, be- cause upon a knowledge of them depends the diagnosis pre- vious to operation and the steps to be taken during its per- formance. It is easy enough to determine beforehand the consistence of a lenticular cataract and afterward to extract or break it up according to its density, but it is often not so easy to predict the amount of resistance to be expected in capsular cataract, or during operation to overcome its toughness or tenacity of attachment. The varieties of capsular cataract are not at all so nu- merous as those of the lens itself. No two of them, it is true, are exactly the same in appearance, but there are fewer species or varieties truly distinct in their nature. There are, however, some perfectly so. The ossified or calcareous degeneration must be held to be one, and that called central cataract is another. This latter is a small defined circumscribed dense, white, opacity, about the size of the head of a pin, occupying the centre of a capsule otherwise ON CATARACT. 37 perfectly transparent. It sometimes Is prominent, pro- jecting from the surface in the form of a cone, sometimes is flat or nearly so. In general, the body of the lens is perfectly transparent where these central opacities of the capsule exist, but sometimes there is also a dense central opacity in it somewhat larger than the other. This cen- tral capsular cataract is sometimes probably congenital, for we cannot ascertain from the patient that it was observed at any particular period, or that it could be traced to any particular cause ; sometimes, however, it exists in eyes having dense and extensive opacities of the cornea from purulent ophthalmia in infancy or from small-pox. I have seen them very small in a lady of sixty, who said that she never considered that her sight was worse than that of other people, and it is probable that after having been once formed they never increase. I have seen them remain un- changed for many years, and when large with a small pupil, I have afforded sufferers from them very useful vision by the daily use of belladonna. One of the most common forms of capsular cataract met with is that which follows operations for cataract or injuries of the eye in which the lens has been wounded. It ap- pears in two very different shapes. In one, it is thick, white, and very opaque ; in the other, a mere film, resem- bling a broken cobweb. The thick, white, opaque capsule, remaining after injury or operation followed by inflamma- tion, either fills the whole pupil and adheres all round to its margin ; or it hangs or projects from its edge in an irregular flap or a rounded prominence. In either case it is as hard and elastic as dry parchment, and if detached by the needle remains undissolved and unabsorbed for a great length of time, on which account I either work a hole in the centre of it with the point of the needle, or detach it from the margin of the pupil all round, except at one spot. 38 ON CATARACT. where I allow it to adhere, finding that in process of time it shrinks and curls up into a white nodule, which, although it projects a little into the pupil, does not obstruct vision. Such may of course be extracted with a pair of forceps, but if they adhere extensively, this is not so safe or so easy of accomplishment as some think. The film resembling a broken cobweb is very common, almost always remaining after injury or operation where the capsule has not been extensively torn, and where inflammation has followed. This often exists in the shape of a few white strings, as thin as fine threads, running from one side of the pupil to the other, and having the intervals between them open and transparent ; sometimes, however, it is a complete conti- nuous film like an irregular cobweb. Such are very tough and difficult to be detached with the needle, the iris not affording sufficient resistance when they are pulled or drawn from it by the instrument. I am often obliged to twist them away by turning the curved needle round and round upon them. In some cases they may be divided with a sharp iris knife or cutting needle. The back of the capsule sometimes, but not often, becomes opaque after operation, and remains so after the lens has been completely absorbed ; such opacities are very delicate, and being far back, are not easily seen ; but with a dilated pupil become visible, and may be torn asunder without much difficulty. What has been called posterior capsular cataract, and de- scribed as existing with a transparent lens is, I am con- vinced, a radiated lenticular cataract in which the opaque striaB are confined to the back and margin of the lens. Capsular cataract never assumes the radiated or striated arrangement. It often happens that both the capsule and body of the lens are opaque at the same time, constituting what are called capsulo-lenticular cataracts. These are generally ON CATARACT. 39 either congenital, or the result of injury or severe inflam- mation, but I have often seen opaque patches in the cap- sule in common lenticular cataracts both of advanced and early life. Sometimes, as has been already observed, the central cataract of the capsule exists with a central opacity of the lens itself. Such a one has been described and de- lineated by Mr. Saunders, and Mr. Wardrop appears to have observed similar examples. In capsular cataracts, either congenital, or in consequence of injury or destruc- tive inflammation, the lens is often found reduced to a white and friable shred or fragment. This has been called siliquose capsulo-lenticular cataract. Congenital cataracts are so called because they exist at birth. They are generally capsular, with a thin remnant of white disorganized lens enclosed, but sometimes they are firm lenticular cataracts with or without opaque cap- sules ; or the lens is opaque in the centre with transparent circumference and transparent capsule. Sometimes, but rarely, the opaque capsule contains a white fluid, and some- times the margin of the pupil is adherent. In fact, some of these cataracts exhibit as great change of structure and disorganization as those caused by severe injury or de- structive inflammation, while others are simple lenticular cataracts, like those which occur in early life generally. As cataracts are not always observed in infants until they are some months old, we cannot say with certainty that they existed previous to birth, as they may have formed subsequently, if merely lenticular and without opacity of the capsule or much other alteration in structure ; but if the capsule or centre be very opaque, or the lens shrunk or otherwise disorganized, we may with safety pronounce them congenital. I am inclined to believe that certain striated or partial cataracts which are met with in growing children commence before birth, because the subjects of 40 ON CATARACT. them exhibit symptoms of defective vision from the ear- liest period, and the progress of the cataract is so gradual that vision is not entirely lost until puberty or even later. True congenital cataracts, however, rarely occur, at least I can say that I have found them uncommon. Mr. Saun- ders, it is true, met with sixty cases in three or four years, but that arose from the success of his new method of oper- ating, attracting patients to him who might have been permitted to continue blind for many years according to the old practice, and many of his cases may not have been congenital at all. It is a remarkable fact that these con- genital cataracts occasionally, if not frequently, occur in more than one individual of the same family, as does con- genital deafness. Mr. Saunders met with them in two brothers in one family, and two others, twins, in another. In a third family, a brother and two sisters were affected ; and in a fourth, three brothers and a sister. I have met with the disease in three children of the same parents, also in two sisters and a brother, and in brother and sister. Mr. Lawrence has observed similar examples. It should never be forgotten that eyes affected with congenital cataract are sometimes otherwise defective, rendering an operation of no avail. In fact, there is congenital amaurosis as well as congenital cataract, and when the retina is insensible with opaque lens it is impossible in young subjects to as- certain before an operation that it is so. The motions and gestures of the child in search of light will afford some guide to the state of the retina, but there may be percep- tion of light without ability to distinguish objects. This has sometimes caused great disappointment to the friends of children operated on, and has brought discredit upon the operator and the operation, but very unjustly, for the operation when properly performed generally succeeds. I think I can say that I never had an eye destroyed by in- ON CATARACT. 41 flammation following operation in young subjects, and I have operated on many. In order to avoid the danger of rendering the subject confused or complicated, I do not enumerate among cata - racts those opacities of the capsule which accompany ad- hesions of the margin of the pupil to it ; but it must not be forgotten that in inflammations of the membrane of the aqueous humour and of the iris, the surface of the capsule, and even the capsule itself, become opaque. Although the membrane of the aqueous humour cannot be demonstrated on the anterior half of the capsule of the lens in a state of health, its presence there may be inferred from analogy and the effects of inflammation. It is only reasonable to conclude that if there be a membrane of the aqueous humour at all, it must extend to all surfaces in contact with that fluid, and the fact that adhesion does take place rapidly and perfectly in iritis, seems conclusive as to the existence of such a serous covering. In inflammation of the membrane of the aqueous humour with or without iritis, there can be no doubt that vision becomes slightly cloudy or hazy from loss of transparency of that portion of it which cbvers the back of the cornea. The speckled opacity is distinctly visible in syphilitic iritis. Opacity of that portion which covers the front of the capsule of the lens is not, however, so unequivocal, although I believe it often occurs, but whether or not permanent is doubtful. Of the frequent occurrence of distinct and well-marked opacities of the capsule where the margin of the pupil ad- heres there can be no question, and when they are exten- sive they must be called capsular cataracts. In almost all cases of iritis which terminate in contraction of the pupil and adhesion of its entire margin to the capsule, that part becomes either entirely or partially opaque ; often with opacity, disorganization, and shrinking of the lens itself. 2 D 42 ON CATARACT. In less destructive attacks the margin of the pupil adheres only at certain points, but at these points distinct, well- de6ned white spots are formed. Opacities from the above causes, and of the above character, have been called spurious cataracts, and the degrees and varieties of opacity have been denominated fibrinous, flocculent fibrinous, clotted fibrinous, and trabecular fibrinous cataract. The term fibrinous, however, ceases to be applicable after some time, as fibrine, if any exists, is either absorbed or con- verted into permanently organized material. THE SO'CALLED STNCHISIS ETINCELAMT. There is a very remarkable and peculiar alteration of the lens which, from its rarity, as well as from its value as an example of extreme degeneration of organized animal struc- ture, is well worthy of consideration ; and especially so, because its nature has been mistaken by persons on the continent who have undertaken to describe it in ignorance of the accounts published in this country respecting its true character. This peculiar alteration or degeneration I described at a meeting of the Surgical Society on the 14th of January, 1843, in the following terms: — " Dr. Jacob called the attention of the society to an ap- pearance which presented itself in the eye of a person upon whom he lately operated for cataract in the City of Dublin Hospital. The man, aged 33, was, he said, what is called amaurotic, or in other words, his vision was very defective even in the other eye which was free from cataract, and therefore he was unwilling to operate from a conviction that he had an unsound retina to deal with ; but at the earnest solicitation of the patient, he consented to let him have the chance which the experiment afibrded. The cataract was lenticular, and although more of an amber ON CATARACT. 43 tint than is usual at this time of life, was otherwise not uncommon. The lens was freely broken up with the needle through the cornea, and was easily separated into pulp and fragments, some of which fell into the anterior chamber, and no inflammation requiring attention followed. In a month the greater part was absorbed, and in six weeks the whole, leaving a shred of opaque capsule attached to the margin of the pupil, but not large enough to inter- rupt the passage of light. As the cataract, however, dis- appeared, the iris became studded with delicate brilliant scales of metallic lustre, so numerous and large as to be easily visible with the naked eye, and still more conspi- cuous with the assistance of a lens. They were irregular in form, but with surfaces so plane and polished that they reflected the light freely, resembling, in a remarkable man- ner, the particles of mica in granite. The appearance con- tinued until the man was discharged, having been visible for about a month, and may probably continue so for some time. Sight, as had been predicted, was not restored, the retina being unsound. Dr. Jacob reminded the society that earthy, and perhaps crystalline deposits in the lens and its capsule were not very uncommon, and that they had been met of so dense a nature as to lead to the appli- cation of the term ossification to them, although not to be considered at all of the nature of real bone. They are probably phosphate of lime, or perhaps ammonio-phosphate of magnesia with phosphate of lime, but that he left to the chemists to determine. He said that on another occasion, in breaking up a cataract of somewhat the same appear- ance, he was surprised to see a quantity of what appeared to be delicate needle-shaped crystals difi'used among the fragments, but these disappeared with the cataract as it was dissolved. He also exhibited a drawing of a capsular cataract, the consequence of injury, which he had removed successfully, and which had presented on the surface an appearance of such metallic lustre that he was obliged to make the artist represent it with silver leaf, and added that these brilliant cataracts, in a less marked form, were not very uncommon, but in all of them the disease was of long 44 ON CATARACT. Standing. Earthy deposits, he observed, were frequently found in the body of the lens in horses blind from cataract consequent on inflammation. The shell of bone sometimes found within the choroid of disorganized eyes, and gene- rally called ossified retina, he observed, was probably of the same nature as these lenticular deposits." I again called the attention of the society to the same subject on the 23rd of November, 1844, as follows : — *• Dr. Jacob said he had some observations to make on a peculiar appearance occurring in a cataract under his care at the City of Dublin Hospital. It occurred in a boy on whom he had operated about five weeks since. He had received a blow on the eye some years before which had cut the cornea and injured the iris, the black membrane of the aqueous humour on the back of the iris being torn from it and dragged in front. This led to cataract, with irregular pupil ; it was evidently an unsound eye, and was one of those cases to which he gave the chance of an operation without any sanguine hopes as to the result. He had broken up the lens, which was soft and pulpy, and thrown the fragments into the anterior chamber in the usual manner. In about a week a large portion of the pulpy matter had been dissolved, but mixed up with the remainder were a number of small brilliant scales, resem- bling particles of gold leaf, perhaps not of so metallic a lustre, but having more the appearance of mica. He called the attention of the students to them at the time, and though they had since then partially disappeared, they were now, in the fifth week since the operation, distinctly visible, moving about in the anterior chamber. They are now fast dissolving, and in a week or ten days will pro- bably have altogether disappeared. He would not offer any conjecture as to the nature of these scales, if he had not recollected a case which had formerly come under his notice. It was an instance of cataract, produced, as well as he recollected, by injury also. On breaking up the lens, he was surprised to perceive it fall into a pulp in the ox CATARACT. 45 anterior chamber, having the appearance of oil altered by cold. Some days afterwards on examining it with a lens of 2^ inch focus, a number of needle-shaped crystals or spiculae appeared moving about in the anterior chamber, each about a line in length. Knowing that the crystalline lens was composed of delicate fibres, he at first imagined that these might be some fragments of it, but all doubts on that point were removed when he discovered that after some days they were not dissolved, but remained even more dis- tinctly visible as needle-form crystals than before, and he was led to consider whether they might not have been crystals of some of the phosphates of lime of the same na- ture as the metallic scales he had been just describing. He thought it very probable that these were crystals of some phosphate of lime, as chemists, in speaking of that substance, described both crystalline needles and crystalline laminae. Some^persons might allege that these were merely fibres of the crystalline lens, but his objection to that was, that being so, they would have dissolved in a few days, while both the scales and needles to which he had alluded continued undissolved in the chamber for many weeks. It might also be objected, that in natural or healthy animal structure no crystalline deposits took place, unless the enamel of the teeth and porcelanous shells might be adduced as instances of such ; but whatever objections might be urged against such an occurrence in health, he would say that they were applicable to diseased conditions of the body. [Dr. Jacob here exhibited a drawing of an- other cataract upon which he had operated in 1839, the surface of which presented a brilliant metallic lustre, and the texture of which, it being capsular and free from in- jury, was remarkabl)- tough and firm.] This he considered somewhat of the same character, but not so crystalline or calcareous. He was not aware that these appearances had been described already, but he should not be surprised if it was so ; for his engagements did rot permit him to search for such a fact in the immense mass of medical mat- ter delivered by the press to the profession in the last few years ; it would be like seeking for a needle in a bundle of 46 ON CATARACT. straw. Other parts of the eye were subject to calcareous deposits, even the cornea had been found with gritty par- ticles in it, and those osseous cups, generally described as ossifications of the retina, were not uncommon. Calcareous deposits in the body of the lens had been described by Mr. Wardrop and others, and such were frequently found in the eyes of horses blind from cataract for many years. Conversion of the capsule of the lens into a material resem- bling egg-shell was not very rare ; all showing that there was no difficulty in admitting that phosphate of lime, or some similar deposit, was often made in the structures of the eye." Notwithstanding these circumstantial descriptions of this very curious form of disorganization, recorded in the 212th number of the Dublin Medical Press for January 25, 1843, and again in the 310th number for December 11, 1844, I find that it has been described and commented on in the continental journals without the slightest reference to my notices. In the Annales d' Oculistique, an ophthalmo- logical journal, published in Brussels by Dr. Cunier of that city, a communication appeared in the number for November, 1845 (nearly two years after my first notice), from Dr. Desmarres of Paris, describing an example of the same disease. It occurred in a woman, aged 58, whose sight began to fail from cataracts about eighteen years be- fore, and who had the operation of depression performed on her left eye seven years, and on the right three years, before Dr. Desmarres saw her ; she then (September 22, 1845,) had dense capsular cataracts, dilated pupils, and tremulous iris, with little sight. These capsular cataracts were removed with a pair of nippers through an opening made in the sclerotic, and good vision followed, but in about a fortnight or three weeks after the following ap- pearances were observed in the left eye : "Looking through the pupil, which was widely dilated, to the bottom of the ON CATARACT. 47 eye, which was perfectly black, I saw (says Dr. Desmarres) scales attached, brilliant as diamonds, moveable, and of a size to be compared only to grains of sand. I'hey occupied different planes in the posterior chamber, appearing gene- rally twenty or thirty at a time ; becoming displaced from below upward with the motions of the eye, and being re- placed by others equally brilliant and numerous. All these little luminous moveable points reflecting the light with a vivid brilliancy, appeared to descend by degrees to the lower part of the eye, when it remained immoveable, and showing themselves in greater number as the motions of the eye were more extensive and sudden. There was no unusual appearance in the anterior chamber, and vision was as good as could be desired after an operation for cata- ract J the patient complaining of some muscce volitantes only. In the same Anndles d' Oculistique for April, 1846, Dr. Sichel of Paris called attention to this subject, and relates a case of the same kind which had occurred to him in 1841 . The patient, a boy, aged 13, suffered from hydrophthalmia of both eyes, the left being much larger than the right, but still so free from disease as to enable the boy to read. In the right, which was soft to the touch, and scarcely sensible to light, was a yellow capsular cataract adhering to the pupil. On tearing this capsule with the needle, a flow of turbid, yellowish liquid took place, mingled with a quan- tity of scales of a golden-yellow lustre, which fell into the anterior chamber and filled it up completely. When this subsided a second flow of semitransparent yellowish mate- rial followed, resembling boiling water in its motion. These appearances continued for several weeks, and some of the brilliant scales were visible even in 1844, three years after. Dr. Sichel adds significantly : " It is astonishing that Dr. Desmarres, who, in 1841 and 1842, being my clinical clerk, 48 ON CATARACT. had seen with me this patient, should have lost all recollec- tion of a fact so difficult to forget, and which gave peculiar interest to that which he himself published." But it ap- pears that neither E, Dr. Sichel, nor Dr. Desmarres first noticed this curious disease, for it appears that M. Parfait- Landrau, an oculist at Perigueux, described it in a com- munication published in the Revue Medicale, t. iv., p. 203, in 1828. The patient was a gentleman, aged 70, who, for several years, had defective vision with muscce volitante^. He says : "On looking into the depth of the posterior chamber, I could perceive little bodies oscillating in the bottom, shining with phosphorescent brilliancy. Notwith- standing the attention I had paid in this examination, see- ing the novelty of the phenomenon before me, which ap- peared of high interest to science, I distrusted my own judgment, and fearing that what I saw was the reflection of some external object, I dilated the pupil with belladonna, when M. Galy, of the hospital of Perigueux, also saw dis- tinctly little bodies like fine powder of liquorice, and amongst the number, which was very considerable, were seen some having the brilliancy of filings of gold. These little bodies oscillated throughout the entire extent of the posterior chamber, and when the eye was at rest fell to the bottom, but on the slightest motion rose and again fell. All this took place at such a distance that no doubt exists that they moved about in the vitreous humour. They were so nu- merous that they were well seen with the naked eye, never- theless we (examined them with a lens. Four days after this, the eye was submitted to a second examination, in presence of Dr. Vidal, a member of the medical jury of the department, and first physician to the hospital, M. Galy, surgeon of the same institution, and M. Renaud, another surgeon : these gentlemen recognized the phenomena above described, and consider it a duty they owe to the interests ON CATARACT. 49 of science to testify as to the correctness of the statements." M. Parfait-Landrau goes on to argue that these appear- ances serve to account for the muscce volitantes and luminous spectra which so often disturb vision, but on this it is not here necessary to dwell. After all this, it seems strange that Dr. Desmarres should, in a work of considerable size on Diseases of the Eye, published in 1847, say : " There is not in science, to my knowledge, any observation similar to this (made by him), not even that of M. Parfait-Landrau."* The reader will perceive that while I described this curious form of disease as occurring in the lens, subsequent writers on the subject referred it to the vitreous humour, and have actually named it accordingly. When the vitreous humour is disorganized by inflammation, and the hyaloid membrane loses its cohesion, the eyeball becomes soft to the touch and the iris generally tremulous j this has been named synckisis, and this supposed variety of it has been dignified with the title of synchisis etincelant, or synchisis scintillans. That the lens is the seat of the disease I enter- tain no doubt whatever. In one case I saw the peculiar ma- terial burst out of the capsule as I opened it with the needle through the cornea, and in the others the scales and needle- * Without wishing to detract from the merits of French surgeons, it is only justice to those of other countries to re- mind the reader that while an acquaintance with the French language is so general elsewhere, that of German and English is very limited in France. Hence the facility with which even trivial communications made by Frenchmen obtain currency in England and Ireland, while valuable information afforded by us remains inaccessible to them ; or what is worse, the in- formation is used without acknowledgment, so as to appear original. This, however, is not perhaps so great an evil as the wilful and obstinate ignorance, or something worse, osten- tatiously displayed in other places, and from which some London writers are not entirely free. E 50 ox CATARACT. shaped crystals were so thoroughly embedded in the sub- stance of the broken up lens, and were so obviously let loose in the aqueous humour as these fragments dissolved, that I could not be deceived. The description of M. Parfait- Landrau, I admit, supports the other view, for he saw these oscillating bodies in an eye which, although defective, was not considered to suffer from cataract ; but as there are forms of cataract in which the capsule of the lens is distended with fluid, this may have been one of them, and in that fluid it probably was that these bodies moved. In Dr. Desmarres' case, the particles appeared upon extracting opaque cap- sules, and had probably been discharged from the lens in the previous operation of depression. Moreover, it does not appear that Dr. Desmarres' patient had any sj/nchisis at all, for he says, after describing the disorganized state of the iris and its adhesions to the capsule, " touies les autres membranes sont saines." And again, *' les yeux avaient leur consistance normale." In Dr. Sichel's case there was a capsular cataract, but there is no reason for assuming that there was not a disorganized lens within it when it was opened. In M. Parfait-Landrau's case there was no softening of the eye, and therefore no syiichisis : in fact, there is no evidence that the disease was in the vitreous humour. As to the possibility of anything floating about in a sound vitreous humour, it cannot be admitted for a moment ; this structure, although a soft and delicate one, is a solid, and in a solid such particles could not move. As to the complete fluidity of this humour, even in soft- ened eyes, much remains to be ascertained by careful dis- section. It is much more probable that decomposition of the crystalline lens would afford products such as these described, than that a structure of such tenuity as the vitreous humour could generate them. The lens of all the structures in the body contains the elements of animal ON CATARACT. 51 organization in a state of the highest concentration, and liable as it is to become detached from its capsule, although still retained within it, presents a condition of parts in no other place to be observed. It is, indeed, when so de- tached, a lifeless material enclosed within living structure, where, although it does not act as a foreign body, it under- goes changes as peculiar as the extraordinary state in which it exists. Since this curious form of disease was noticed, much discussion respecting its nature has been carried on in the continental journals ; in which Dr. Stout of New York, Dr. Blasius of Halle, Dr. Bouisson of Montpelier, M. Petrequin of Lyons, and MM. Tavignot and Robert in Paris, have taken part. I cannot, however, discover that any material addition has been made to the descriptions given of it by M. Parfait-Landrau in 1828, and by me in 1843 and 1844. It has been suggested that the crystalline scales and needles are of the nature of cholesterine, but no evidence of it has been afforded, and it seems impro- bable that delicate and minute particles of such a material could remain unchanged in the aqueous humour for months or perhaps years. I have devoted more space to this in- quiry than perhaps it is worth, but the circumstances stated compelled me to do so. OF THE CAUSES OF CATAKACT. Cataracts, in the majority of cases, are the consequence of the change which takes place in transparent parts from age, or of inflammation, or accidental injury. We every day, it is true, see cataracts which we cannot trace to any cause, but that many are owing to either of these three causes can scarcely be denied. It has already been shown that the lens undergoes three obvious changes as we i»2 ON CATARACT. advance in life. It becomes harder, acquires an amber colour, and is flattened, or rendered less convex. In ad- dition to this, it frequently, if not generally, loses its per- fect transparency, and becomes slightly opaque, milky, or clouded ; which, if increased, causes such obstruction to the transmission of light, that it constitutes cataract, and impairs or destroys vision. These changes, which the lens undergoes in common with other structures, in some cases proceed to still more remarkable alterations. StricB, or veins of white opaque matter form, or the fibrous texture separates, and it splits into segments, as has already been stated. This being the case, it does not appear unreason- able to attribute the various forms of cataract which are seen in old persons to these organic changes where no evi- dence exists of the operation of other causes. That cata- ract, both capsular and lenticular, is often caused by in- flammation cannot be denied. In general inflammation of the whole eye, commonly called iritis, terminating in contraction of the pupil, with close adhesion of its margin to the capsule of the lens, not only is the capsule rendered opaque, thick, and hard, but the lens itself is reduced to a white, shrunk, disorganized mass ; and when the pupil is not contracted or adherent, but dilated, the body of the lens becomes opaque and of a greenish-amber tint, often called glaucomatous. These effects of inflammation are obvious, but opacity from less marked internal inflamma- tion of the eye is not so unequivocal. I am, however, satisfied that in those slow insidious forms of inflammation which destroy the retina and cause what is called amauro- sis, the lens is frequently rendered opaque ; and to this cause are many of the soft blue lenticular cataracts of earlier life to be attributed. Not only am I satisfied that this is the case, but I am convinced that in many casein this form of inflammation causes opacity of the lens with- ON CATARACT. 53 out destruction of the retina or amaurosis, and hence the doubt which must exist as to the success of operations in such cases. That central opacity of the capsule follows penetrating ulcers of the cornea, or slough in the purulent ophthalmia of infants, and the ulceration from pustules in small-pox, has been already stated, and it appears only reasonable to attribute such opacity to the inflammatory action which accompanies these ulcerations. That cataract is produced by injury, no one will, I believe, deny. Puncture of the capsule by a sharp in- strument, as often occurs from the accidental thrust of an awl, a fork, or a needle, or from a thorn by a slap of a bush in crossing a hedge, is immediately followed by opacity or cataract. I think I have seen the lens quite milky in ten minutes after the accident. In fact, the moment the capsule is torn open, the soft fibrous lens begins to imbibe the aqueous humour, and speedily ex- pands, and becomes opened in its texture, at the same time losing its delicate transparency and acquiring a milky appearance. The capsule of the lens is sometimes, al- though very rarely, burst by a blow, without any penetrat- ing wound of the eye, causing opacity of the lens, and its ultimate absorption. But not only is the lens rendered opaque in this way, but it is a fact, that a blow on the eye sometimes causes opacity without rupturing the capsule at all. How this happens is not very certain, but it may be caused by the detachment of the lens from its connexion within the capsule by the shock of the blow ; or it may be, that the cataract in such case is a consequence of inflam- mation from the injury. It has been said that cataract sometimes takes place sud- denly, and this has been attributed to rupture of the cap- sule in convulsions, but I very much doubi the truth of these statements. I never yet met a patient who had 54 ON CATARACT. cataracts in both eyes and could prove that they took place suddenly, although I have met many who asserted that single cataracts had appeared on one particular day. The real truth being, that blindness of one eye from cataract, or any other cause, may exist for a long time without a person being aware of it, until informed by attempting for the first time to view an object with that eye, the. other being closed, or until it is observed by another person. Every one con- versant with diseases of the eye must have observed how often very imperfect vision of one eye exists without the patient knowing it ; so little are some persons in the habit of observing or paying attention to occurrences which do not materially affect them. Of remote causes of cataract we have little evidence. Hereditary predisposition is generally considered to exist, and perhaps there may be some truth in the conclusion, but I cannot say that 1 have been able to establish the fact in a sufficient number of cases to justify a positive assertion of its operation. Exposure to strong light and heat has been enumerated among the remote causes ; and cooks, glassblowers, workers in foundries, and smiths, have been held more liable to the disease than others. Experience, however, does not verify such statements, which have pro- bably been repeated by successive writers upon some re- mote authority not much to be relied on. Mr. Mackenzie says he met with the disease at one time frequently among stocking, weavers, and I, if I instituted an inquiry into the matter, should probably say that the disease occurred most frequently among labouring people. Chance may throw more cases of particular trades into one man's way than another. Constitutional disease, or derangement of im- portant vital functions, might be supposed to be cal- culated to induce this disease, but it does not appear to do so. Neither scrofula, cancer, nor venereal, except so far ON CATARACT, 55 as they may cause it by leading to inflammation, seem to produce it. Mr. Mackenzie says he met three instances in cases of diabetes mellitus, and I think I have myself seen two or three also. OF THE SYMPTOMS AND PROGRESS OF CATARACT. When sight becomes impaired, without opacity of the cornea or contraction of the pupil, the defect is naturally attributed either to opacity of the lens or loss of sensibility of the retina; in other words, to cataract or amaurosis. It is, therefore, necessary in such cases to ascertain how far the disease is owing to the one or the other. The patient in both cases complains of loss or imperfection of vision, but in cataract he complains of a cloud, fog, or smoke in- terposing between him and objects ; while in amaurosis he rather thinks that he cannot see from want of light, or some inexplicable inability to distinguish objects. In cataract, I think that the patient when nearly blind can judge better of the form, colour, and distance of objects, than he can in amaurosis impairing vision to the same ex- tent. In both, ocular spectra, muscae volitantes, floating motes, smuts, and films, with or without luminous clouds and scintillations, may be present, or they may not exist in either, being I believe consequences of inflammatory action. In incipient cataract there is generally a change in the optical construction of the eye, causing indistinct- ness of vision and loss of power of adaptation and adjust- ment. So much so, that in many cases temporary relief is derived from the use of lenses of short focus, and in near- sighted persons concave glasses are abandoned, which is not so much the case in amaurosis. In incipient cataract, also, objects often appear distorted and multiplied ; the 56 ox CATARACT. print in a book appears thrown out of line, and the sashes of the window appear doubled. The candle, also, often appears as if with rays extending from it, and the circular disc of the full moon appears broken at the edge, or the candle and lamps in the street appear enlarged, and not sharply defined ; while in amaurosis there is more of hazi- ness, with spreading of the luminous point into a diflfused patch. In cataract, patients generally see a little better with the back to the light, or even in a weaker than in a stronger light, because the pupil is then enlarged, and a larger passage is formed for the transmission of the rays ; while in amaurosis vision is improved in strong light, un- less there be an irritable or excitable state of the retina from inflammatory action. The admission or assertion of a patient as to the existence of all or any of these symp. toms, cannot, however, be considered conclusive of evi- dence of incipient or advanced cataract, there must be some visible opacity of the lens to justify us in pronounc- ing positively that the disease is present. Yet even this is not so easily ascertained as might at first sight appear. On looking into the eye, an observer may perceive a degree of cloudiness or milkiness of the lens which may lead him to believe that cataract has commenced, but he must not decide too hastily from this, because a perfectly transpa- rent lens seen through a naturally large pupil, or through one dilated by belladonna, with the light reflected from its surface, appears milky ; and in aged persons the amber- coloured lens, viewed under similar circumstances, appears very opaque, although really not passing into the state of cataract at all. If the defect of vision be but slight, and the opacity but inconsiderable, it is not easy to determine positively whether or not the defect is to be attributed to the opacity or to the state of the retina, but when vision is nearly lost from cataract, the opacity is so obvious that ON CATARACT. 57 there need be no doubt on the subject. In fact, if a patient declares that he can only distinguish light from dark- ness, or that he can merely perceive that the hand is passed back and forward before his eyes, there must be visible cataracts to account for such blindness ; and if there are none, or if there is only a slight milklness of the lens, the blindness must be referred to the retina. In other words, if a man be blinded by cataracts, we have only to look into his eyes and see them. It is in incipient cataract that any difficulty exists of ascertaining the nature and amount of the opacity, or of discovering that it is owing to this cause and not to incipient amaurosis that the defective vision is due ; and it Is therefore in such cases that dilatation of the pupil by belladonna must be resorted to in order to obtain a full view of the lens. With this most valuable aid, and with the assistance of a good large convex lens of about two and a half or three inches focus, I can with safety say that I never fail to satisfy myself on the subject ; slight opacities, whether general or partial, becoming thus dis- tinctly visible, especially when a strong light is reflected from the surface of the lens to the eye of the observer, or when not so reflected, he looks deeply into its texture. I must, however, warn those who have not acquired the art of adjusting a lens so as to bring it to the proper place between the eye of the patient and the observer, that they must not expect satisfactory results from this method of examination. I have also to warn beginners against re- sorting to the dilatation of the pupil by belladonna without some consideration, especially in aged persons ; because the effect of such dilatation in a sound eye is to cause great defect of vision while it lasts, and often in incipient cataract the same result follows, and is immediately felt by the patient, who ever after attributes his loss of vision to this cause. 58 ON CATARACT. In endeavouring to arrive at a correct diagnosis of cata- ract, the way in which the patient carries his head and directs his eyes may be worth noticing. In cataract, some vision always remaining, the patient continues to direct his eyes in search of objects ; while in amaurosis, especially if complete, there is a vacant stare which pro- claims that he cannot see, and that he feels that there is no use in attempting to do so. The state of the pupil and power of contraction in the iris is also worth noticing, al- though frequently aflfording little additional information. If the pupil be permanently dilated, we may generally conclude that the retina is insensible to light whether there be cataract or not, but mere sluggishness in the action of the iris, or even immobility of the pupil, should not be considered conclusive evidence of amaurosis; because in aged persons especially, the iris very often loses the power of active dilatation and contraction without any corre- sponding defect of vision. It seems to be very generally assumed that if the retina becomes either partially or entirely insensible to light, the pupil must of necessity be dilated, because in the sound eye it is dilated when light is diminished ; but experience teaches us that in the majority of cases of amaurosis there is no dilatation of the pupil. In the same way it is, or it may be, inferred that when light is excluded by cataract the pupil is dilated, but we know that it is not so. Consequently the state of the pupil does not assist us much in our diagnosis of cata- ract. If, however, in younger persons the pupil neither dilates nor contracts under changes of light, with or without cataract, insensibility of the retina may be inferred. Much unnecessary doubt has been created with respect to the diagnosis of cataract by giving to certain combina- tions of cataract and amaurosis another name ; and de- scribing under the title of glaucoma appearances which ON CATARACT. 59 depend upon the presence of an amber-coloured lens with extensive alteration of structure in the other parts of the eye. Glaucoma appears to me to bo merely that state which follows general inflammation of the eyeball of chronic character in persons more or less advanced in life. The bloodvessels are permanently enlarged, the pure white of the sclerotic is changed to a yellowish or dusky tinge, and the cornea and lens, and perhaps sometimes the vitreous humour, lose their perfect transparency and freedom from colour ; the pupil being at the same time dilated, and the eye soft from disorganization of the hyaloid membrane. This is not progressive disease, but the consequence of dis- ease ; in fact, the effect of inflammation, the existence of which it is very important to ascertain where cataract is in question, but which we need not seek to distinguish from cataract, for frequently that disease is accompanied by this very state of the eye. Opacity of the lens may properly be called cataract, and loss of sensibility of the retina may also be called amaurosis ; but I cannot see the necessity of calling amaurosis with a yellow lens glaucoma. Much has been said and written about another method of detecting incipient cataract. It is called the catoptrical test. A lighted taper is to be held a few inches from the eye, and moved from side to side and up and down. If the lens be perfectly transparent, one upright image of the taper is seen reflected from the cornea ; a second, also upright, supposed to be from the anterior face of the lens ; and a third inverted, supposed to be from the back of the lens. If the lens be opaque, the third or inverted image is either|.indistinct or absent. To this method I have not in my own practice attached much value, because I find that if the sensibility of the retina is considerably impaired or destroyed, or in other words, that the eye is amaurotic, and that at the same time the lens is perfectly transparent, 60 ON CATARACT. I have only to look into the eye and see that it is so ; and if, on the other hand, vision is much impaired, and the lens so opaque as to obliterate the third inverted image, I have also only to look and see it. Besides, I believe that in many old persons the lens is so coloured and milky, although not aflfected with cataract, that no inverted image is seen in their eyes. Many may, however, find the method useful, for it is relied upon by Dr. Mackenzie and others as a valuable means of diagnosis. My myopic eyes, too, which I find so available in minute operations, may not admit of that ad- justment which this experiment requires, and therefore perhaps it is that I do not find it answer. Without ad- vancing any claim to superior address in the investigation of the state of the lens when supposed to be partially opaque, I may observe that I have often felt surprise at the appa- rent difliculty experienced by observers in determining the question. With a glass of short focus and a strong light reflected from the surface of the capsule, I seldom find it necessary even to dilate the pupil in order to satisfy myself as to the condition of the lens. Persons with presbyopic eyes may not, however, find it so easy to accomplish the same object, because they cannot so easily adjust the eye to bring an exceedingly minute portion of an image to its place on the retina. Whatever inconvenience may be expe- rienced in early life by short-sighted persons, it is counter- balanced by this state of vision at a more advanced period, enabling them to pursue occupations which they should otherwise be compelled to abandon. ON THE OPERATION THE REMOVAL OF CATARACT, AS PERFORMED WITH A FINE SEWING NEEDLE THROUGH THE CORNEA. ARTHUR JACOB, M.D., F.R.C.S. PROFESSOR OF ANATOMY AND PHYSIOLOGY IN THE ROYAL COLLEGE OF StlRGEiNS IN IRELAND, AND SURGEON FOR DISEASES ^)F THE EYE TO THE CITY OF DUBLIN H(SPITAL. DUBLIN : PRINTED AT THE MEDICAL PRESS OFFICE. 1850. DUBLIN : PRINTED AT THE MEDICAL PRESS OFFICE. CATARACT. OPERATION THROUGH THE CORNEA WITH THE NEEDLE EMPLOYED BY DR. JACOB. The following paper was published several years ago in the Dublin Hospital Reports. I now republish it because these valuable volumes have become scarce, and are con- sequently out of reach of the majority of practitioners, and because I have, within the last year, had frequent applica- tions for information on this subject. I am also induced to direct the attention of surgeons again to this method of removing an opaque lens, in consequence of the want of confidence reposed in it by many from an imperfect acquaint- ance with its practice. My experience as to the use of this needle, and the selection of the cornea as the place for its introduction since the publication of this paper, leads me to express still more strongly than I have done my con- viction of the superiority of this operation. I think I can with safety state that I have performed it more frequently, and practised it for a greater length of time, than any man now living, and therefore do I think that I have a right to speak of its merits without hesitation or fear of contra- diction. Many will probably think that I form a false estimate of the value of my experience in this matter, or perhaps that I am not aware of the amount of experience which others have acquired respecting it ; but when I find, 4 OX CATAKACT. what I consider, the best method of repairing one of the greatest losses which man sustains from disease or accident, undervalued, I am compelled to advocate its adoption, re- gardless of anything that may be said respecting my motives for so doing, or the means I employ to accomplish my object : "Without taking part in the protracted discussion re- specting the comparative merits of the different operations for cataract, I shall recapitulate the arguments which have been urged in favour of that operation, to which I consider the needle, which I have to describe, as particularly appli- cable. The operation to which I allude is that of opening the texture of the lens, to produce its absorption by expos- ing it to the action of the aqueous humour.* • Surgery is indebted to Mr. Pott for the important fact, that cataract may be removed by absorption, if exposed to the contact of the aqueous humour by opening the capsule; and doubly indebted to Mr. Saunders for establishing by re- peated operations the value of the suggestion. Attempts have lately been made to transfer the credit of this improve- ment to others. Mr. Guthrie first gives the merit to an old lady, contemporary with Theodore Mayerne, and then, with more reason, to Paul Barbette ; but as the works of these authors have not been republished since 1690, and as the copies e-xtant are not of frequent occurrence, it must be allowed that it is probable they were not plundered by Mr. Pott and Mr. Saunders. Frick, an American writer, attri- butes the improvement to Gleize, who himself actually gives Mr. Pott tlie credit of the discovery. Among other technical terms in ophthalmic surgery intro- duced from Germany, we have that of Keratonyxis applied to this operation generally, although it can have reference to the anterior operation only ; and with the word, we have the claim of Dr. Buckhorn to the anterior operation, which Eng- lish surgeons have been practising for nearly twenty years at the suggestion of Mr. Saunders, and this on the grounds that Dr. Buckhorn published an Inaugural Dissertation on the subject in 1806, ON CATARACT. 5 The strongest argument in favour of this operation is, that it is the most easily performed, affording a valuable resource to the surgeon, who, unpractised in extraction, wishes to avoid the evil consequences of depression. An- other argument scarcely inferior in weight to the last is, that the injury inflicted on the organ is much slighter than in extraction, where so extensive a wound of the cornea is made, or in depression, where the vitreous humour is neces- sarily lacerated, and the retina frequently injured. If the objections to depression be well founded, recourse must be had to this operation in those cases where extraction is in- eligible or impracticable. If after the operation has been commenced the lens is found too firm to yield to the needle, extraction may immediately be performed. It is, if not the only operation applicable to capsular cataract in general and congenital in particular, at least the preferable one : where the eye cannot be fixed without subjecting it to considerable pressure, it is obviously to be preferred. It is urged as an objection to this operation, that it is appli- cable to cases of soft cataract only. Whatever meaning may be attached to the term soft cataract, my experience leads me to the conclusion', that the operation, properly modified, is applicable to the great majority of cases, per- haps to nine in ten. It is said that it often requires to be repeated ; but this is a minor evil to which we submit, in preference to incurring the risk of either of the other oper- ations. Extraction, if unsuccessful, cannot be repeated, and a repetition of depression is not very desirable. It has been said, without the least foundation in truth, that vision is not as perfect after this as after other operations ; the reverse is, I believe, generally speaking, the fact. That more time elapses between the performance of the operation and the recovery of sight than in the other oper- ations must be admitted ; but this, which may be a very 2 A C ON CATARACT. valid objection on the part of metropolitan oculists, many of whose patients come from a distance, cannot be consi- dered of great importance elsewhere, the disadvantage of delay being counterbalanced by the greater security af- forded by the mildness of the operation. From the cir- cumstances above stated, it appears that this operation must be, and is, very generally resorted to by surgeons, and therefore any attempt to improve it should be treated with indulgence. It has been a subject of some controversy, whether this operation should be performed by introducing the needle anterior to the iris, through the cornea, or posterior to it, through the sclerotic ; and hence the terms anterior and posterior operations. The strongest argument in favour of the anterior operation is, that the injury inflicted is much less, the needle being passed through the cornea only ; while in the other case it is passed through the scle- rotic and choroid, wounding the ciliary processes, and pro- bably often pricking one of the ciliary nerves. The scle- rotic being a fibrous membrane, there is every reason to apprehend the consequences which generally result from injury of structure of that description ; added to which we have the consequences of the injury sustained by the cho- roid. On the other hand, there are few varieties of struc- ture which bear injury so well as the cornea: it heals rapidly when scratched or wounded : the extensive inci- sion made by the extracting knife heals in a short time, although exposed to the friction of the eyelids, and bathed in tears : the wound of a cataract needle is closed in a few hours : if a staphyloma, or a dropsical eye be opened, a portion of the cornea must be removed, or a foreign body introduced, to prevent the orifice from closing. Wound of the iris may occur in either operation. That the lens can be more effectually lacerated, and its texture opened, ox CATARACT. 7 by introducing the needle, of which I shall presently speak, through the cornea, I am quite satisfied. Some high authorities, among whom is Mr. Travers, are inclined to think that the objections urged against the pos- terior operation, on the ground of the injury sustained by the sclerotic and choroid, exist in theory only. I am, however, inclined to believe that those evils which we are justified in apprehending from the nature of the parts in- jured, actually do occur, and that the posterior operation is more frequently followed by destructive inflammation than the anterior. There can be no doubt that surgeons become biassed in favour of the operation which circum- stances have led them to adopt, but the opinion of Mr. Saunders, who practised both operations, should have great weight. He says (p. 149) : 'The surgeon has more power in the posterior than the anterior operation ; but the latter excites less pain and inflammation, and inflicts a slighter, if any, injury on the vitreous humour.' The surgeon who would succeed in restoring vision, by exposing the lens to the contact of the aqueous humour, should never forget that the most formidable impediment to his success is the inflammation which follows the oper- ation ; and that his aim should therefore be to accomplish his object with the least possible injury to the organ. He must also recollect that the lens displaced, whether whole or in fragments, is equivalent to a foreign body in the eye, and must therefore be so disposed that it shall not press on the iris. A notion very generally prevails, which I cannot but call a very mistaken one, that it is necessary to place the fragments of the lens in the anterior chamber to accom- plish their solution and absorption. The inexperienced operator may rest assured that if he adopts such practice indiscriminately he will have reason to repent of it. Sir W. Adams, describing such a proceeding, says, after no- ON CATARACT. ticing the method of introducing the instrument : * I then turn the edge backwards, and with one stroke of the in- strument, cut in halves both capsule and cataract. By repeated cuts in different directions, the opaque lens and its capsule are divided in many pieces, and at the same time I take particular care to detach as much of the cap- sule as possible from its ciliary connexion. As soon as this is accomplished, I turn the instrument in the same direction as when it entered the eye, and with its flat sur- face, bring forward into the anterior chamber as many of the fragments as I am able.'* It happens luckily for those who attempt such an operation that it cannot often be accomplished : a lens must be very soft indeed which could be cut across, and chopped into fragments, upon a struc- ture affording so little resistance as the vitreous humour ; if it yielded so easily under the edge of the knife it must also break under the needle in depression. Portions of cataract will certainly dissolve more rapidly when placed in the anterior chamber, because they are completely immersed in the aqueous humour, while in the posterior they have perhaps only one surface exposed ; but it is absurd, and contrary to experience to suppose, that they cannot be dissolved behind the iris. I quote one or two passages from the work of Mr. Saunders to enable the reader to contrast his mild, delicate, and successful operation with the practice to which I allude : — 'As soon as the needle has penetrated the tunics, he gently depresses its handle so as to direct its point towards the capsule through the thin edge of the lens, and steadily projecting its flat surface between the capsule and lens, he arrives at the centre of the capsule, which he opens, taking the same precaution as in the anterior operation, not to rend it extensively, * See his work on Cataract, p. 255. ON CATARACT. i) lest he should dislocate the lens. He now cautiously opens the texture of the lens, and withdraws the needle. In his subsequent operations, he will complete the central aper- ture in the capsule, and then loosen the texture of the lens, suffering the flocculi to full into the anterior chamber, but not projecting into it amj considerable portions of the lens, for the process of its solution and absorption is best accomplished in its natural position.'* I must not, however, be understood to say that the fragments of the lens are in no case to be brought into the anterior chamber. A cataract is often soft and friable, falling almost to a powder under the needle j in such case the fragments necessarily fall into the anterior chamber, so as to fill it half way up, and are afterwards rapidly ab- sorbed without producing inflammation : such are certain lenticular cataracts of a blue tint, not generally found in old persons. If, however, the fragments be larger than the head of a common pin they are liable to produce in- flammation by pressing on the iris, which pressure can only be obviated by keeping the pupil completely dilated by belladonna, an object that cannot always be accom- plished. I have frequently had an opportunity of witness- ing the solution of cataract in situ after the capsule had been opened, and I could with a magnifying glass observe from day to day the change in form which occurred from the removal of particles of cataract, until at last a portion has disappeared, and left a passage for the light. In such a case I observed three several times, that when a small frag- ment fell out of the capsule into the anterior chamber, pain and slight inflammation supervened, and continued until the particle was absorbed. In cases of hard cataract I do not attempt to break up the lens, because it would certainly be * Treatise on Diseases of the Eye, p. 147. 10 ON CATAllACT. dislocated from its situation in the capsule in the attempt ; I merely open the cataract, as directed by Mr. Saunders, and as much of the lens as I can with safety, leaving it for a future operation, when the lens shall be found softened, and capable of being broken down into small fragments. Another circumstance which has interfered with the success of the surgeon in this operation, is his forgetting that much time is required to accomplish the absorption of a lens, and consequently neglecting to prepare his patient for the delay. In cases of congenital cataract Mr. Saunders says (p. 149) : ' The number of operations which may be necessary to accomplish the cure of a congenital cata- ract will very much depend on the texture of the capsule and the size of the lens. It is frequently cured by a single operation, more frequently it requires two, often three, sometimes four, but very rarely five. This period of cure will of course depend on the same circumstances. Some are cured in a few days, the greater number in one or two months, in many the process is protracted to three, and in a few to four or even five months.' The common period I have found to be from two to five months ; soft cataracts are of course more rapidly dissolved. Occa- sionally cataracts operated on in this way disappear in a few days, not from being absorbed, but, as I conclude, from falling down into a fluid vitreous humour ; as I have observed to take place in eyes otherwise diseased, espe- cially with a tremulous iris. I have learned to look upon such an occurrence with apprehension, notwithstanding that it is attended by an apparent cure. Surgeons fre- quently in their anxiety to obtain a speedy cure, sacrifice all prospect of success by too early a repetition of the operation. While the broken lens lies well in the pos- terior chamber, without pressing on the iris, the operator has reason to congratulate himself, and it is only when he ON CATARACT. 1 1 has ascertained that no change is taking place in the cata- ract, that he is called upon again to disturb it. He should be particularly cautious not to repeat the operation while any trace of inflammation exists. If the surgeon determines to adopt this operation of open- ing the texture of the lens through the cornea, he has next to make choice of the instrument which will accomplish this object most effectually, and with least injury to the organ. I conceive that all that is required for this pur- pose is a fine point ; a cutting edge or knife being only required where the lens is to be cut in pieces. I also con- sider that the needle should be curved at the point, to enable the surgeon to open completely the texture of the lens if it should prove soft or friable, and it should be so constructed that the aqueous humour shall not escape. It is obvious that these objects cannot be attained by the use of the old spear-pointed couching needle, or by the smaller needles of Hey or Scarpa, unless they are very much dimin- ished in their proportions. The flat needle of Mr. Saun- ders, however successfully used by him, is objectionable on account of its straight form, and the impossibility of rolling it between the fingers to produce the effect of a drill on the lens. That the modifications of Scarpa's needle, re- commended by Langenbeck and Guthrie, may be employed with the best effect, there can be no doubt ; but I have to object to every needle fabricated by a cutler, that, however delicately the instrument may be formed, it is liable to leave a mark in the cornea, and when made very small to guard against this occurrence, can seldom be obtained of the proper temper and finish : if too soft they bend, or if too hard, break. To attain the desirable objects stated above, and to avoid the difliculties to which I have just alluded, I determined to try a fine sewing needle curved at the point, and after about forty operations I do not feel 12 ON CATAKACT. in the least inclined to repent of ray choice. I am on the contrary every day more and more satisfied that it affords peculiar and unquestionable advantages. It rarely, if ever, leaves even the slightest mark in the cornea. I could produce examples where it has been three times introduced, and where not the slightest speck can be detected ; and I have introduced it through the very centre of the cornea without any bad consequence. When fairly introduced into the eye, it is capable of accomplishing any object to be attained by a needle. The capsule can be opened to any extent : a soft or friable lens can be actually broken up into a pulp, by pushing the curved extremity of the needle into its centre, and revolving the handle between the fingers ; large fragments can be taken up on the point of the needle from the anterior chamber, and forced back out of the way of the iris, or if sufficiently soft, may be divided by pressing them against the back of the cornea with the convexity of the needle ; a method which I have repeatedly adopted with advantage. When the lens has been displaced from the capsule, in consequence of the needle sticking in it in attempting to open its texture, I have, without removing the needle, placed the lens in the anterior chamber, and then extracted it ; and in other cases have forced it back into the vitreous humour, out of the reach of the iris. From the fineness of its point, and the ease with which it can be turned and twisted in every direction, it enables the surgeon to deal most effectually with an opaque capsule ; he may pick it with the point from any attachment it may have formed to the iris, or if it hangs flaccid he may entangle and detach it by pulling or twisting. In certain cases the pupil is found nearly closed, and adhering to a small cataract of nearly cartilaginous hardness ; in these I have introduced the needle, and with the point picked up the adhesions between the margin of ON CATARACT. 13 the pupil and this hard mass, which I have then placed in the anterior chamber, and removed through an opening in the cornea, with a pair of forceps. It may be said that all this might be accomplished by a diminutive needle on the plan of Scarpa's ; but not, I conclude, with the same pro- spect of success, on account of the much greater size of even the smallest of such needles. There is one difficulty attending the use of the round needle : it requires very considerable force to pass it through the cornea ; so much indeed as frequently to em- barrass those who use it for the first time. I can, how- ever, safely assert that very little practice enables the surgeon to surmount this difficulty. It is only necessary that he should be aware of the degree of force required, that force he is perfectly safe In employing. The surgeon who rejects an instrument which affi^rds peculiar advan- tages, or refuses to adopt superior methods of operating, because difficulties in execution stand in his way, can never expect to obtain the character of a good operator. The greatest advantage in the use of the needle results from the very circumstance which causes the difficulty in its introduction, it is from its conical form firmly wedged in the cornea, prevents the aqueous humour from escaping, and in consequence of being thus fixed, gives the surgeon a power of holding the eye that defies every etCort on the part of an unruly patient, unless he actually plucks out the instrument with his hand. If the head be suddenly drawn back the surgeon has only to let the instrument rest loosely on his hand, and follow the motions of the patient. I have seen the needle under such circumstances slip from the hand of the surgeon, and hang from the eye without seri- ous mischief, the handle being very light. The size of the needle is known in the shops as number seven, being the forty-fourth part of an inch in diameter, 14 ON CATARACT. about one-half the size of the finest Saunders's needle which is made. The point can be turned to the requisite curve by means of a pair of cutting forceps, or the ward of a small key ; of course without heat, which would destroy the temper. It must not, however, be expected that all needles are so soft as to be bent thus cold : there may not be ten in an hundred of this temper, but when once turned they retain the curve without any danger of bending or breaking, and certainly possess a degree of strength and temper never observed in needles separately forged and finished by the best cutlers. They should always be tried before use by passing them repeatedly through thick calf- skin leather. After they have received the requisite curve, the point should be cut flat on each side, on a fine hone, and carefully examined with a magnifying glass to ascer- tain that it is perfect. The extent to which the point should be curved may be left to the choice of the sur- geon, reminding him that the greater the curve the more efiectual the needle will be when introduced, but the difficulty of introducing it through the cornea will also be greater. I therefore recommend those who use it for the first time to choose one slightly curved. After the point has been turned, the needle, held in the jaws of a pair of pliers or a vice, is to be run down into a cedar handle, without cement, leaving only half an inch of blade, which I have found to answer every purpose. If the blade be left longer it will yield and spring when opposed to a re- sistance. The handle should be about a fifth of an inch in diameter, and four inches long. I use the handles made for camel-hair pencils, and find that a metallic ferule, which increases the weight, is unnecessary and objectionable. A needle thus constructed, and preserved free from rust, will retain its point for a great length of time : I have used the same one a dozen times without sharpening. ON CATARACT. 15 The surgeon, provided with such a needle, places himself in the usual position with respect to the patient, availing himself of whatever assistance he may find necessary to secure the lids.* He then brings the point of the needle within a very short distance of the eye, and when the cornea is brought into an advantageous position, he sud- denly strikes the needle into it near its circumference. As I do not apprehend any opacity from the wound, I am not very particular with respect to the precise point where the needle pierces ; I generally, however, enter it sufficiently near the margin to obviate defect from this cause. The point of the needle once fastened in the cornea, the sur- geon has complete command of the eye ; no action of the muscles can disengage It, and there Is no danger of the needle slipping into the anterior chamber ; an elevator or ophthalmostat is therefore altogether useless. The operator now pushes the needle through the cornea, which frequently yields like wet leather, and the eye often turns so much toward the inner canthus that the pupil is hid, and he must rely upon his knowledge of the course which the needle necessarily takes, in order to conduct It to the lens. This is the principal difficulty to be surmounted. If the sur- geon does not now steadily push the needle forward, what- ever resistance he may feel, he will find, when the eye re- turns to Its proper position, that the point of the needle is still merely entangled In the cornea. This also is the period of danger to the iris : if the operator does not keep the flat of the needle to that membrane, with the point * Some ophthalmic surgeons recommend that the left hand be employed to operate on the right eye, supposing the oper- ator to sit in front of the patient. I operate on the left eye sitting opposite to the patient, on the right standing behind him with the head resting against my chest ; this latter posi- tion I find by far the most favourable and convenient. 16 ox CATARACT. down and the convexity up, he will be very liable to injure it. Should it happen that the point of the needle has passed through the iris, it may be easily extricated by gently drawing back the instrument without removing it from the eye. After the needle has been fairly entered, and that the operator sees its point at the opposite side of the pupil, he brings the cornea forward merely by pulling it upon the needle, to which it is completely secured, in consequence of the blade being wedged into its texture. He now turns the point directly back, and gently tears open the capsule, picking and scratching the surface of the lens with a rotatory or drilling motion of the instrument; not with the lever or cutting movement, which is necessary when Saunders's needle is used. If the lens be soft and friable, the fragments fall like snow into the anterior cham- ber, and the surgeon may deal very freely with it, pushing the needle deep into its structure, and twirling the point round so as to mash it into a pul^. If, however, it proves hard, and that he attempts to deal thus with it, he fixes his needle in its tough and glutinous structure, turns it out of the capsule, drags it against the iris, and makes it necessary either to extract it or force it back into the vitreous humour. As I have already observed, if the cataract be hard, the capsule should be opened, and the centre of the lens cautiously scratched with the point of the needle, so as to expose its texture to the contact of the aqueous humour, by which it is softened and fitted for breaking up on a future occasion. In withdrawing the needle the surgeon has to encounter the same descrip- tion of difficulty which attends its introduction ; it is tightly held by the cornea, requiring to be turned on its axis in order to extract it, as an awl is drawn from leather. It must not, however, be forgotten that this wedging of the instrument is attended with the great advantage of ON CATARACT. 1 ( enabling the surgeon to operate on the most unsteady eye without an ophthalmostat or elevator. While advocating the merits of this instrument I am not ignorant of the proposal of Buekhorn and others to employ a round needle. I have not, however, been able to ascertain from the books what is the precise form and size of Dr. Buckhorn's instrument, and as I have not seen his Essay I must be excused if I have been repeating what he has already stated. Scarpa's needle is round in the stem, but it is spear-pointed, and consequently allows the aqueous humour to escape ; a disadvantage that must attend the use of every needle so constructed. In the needle which I have been describing we have combined the advantages of a delicately small blade, of great strength and fine temper, inflicting so minute a wound that no mark remains in the cornea, capable of opening the texture of the lens as effectually as any other needle, and from its conical form, not permitting the aqueous humour to escape during the operation." Since this paper was published, I have continued to practise this operation as described in it, and with the needle proposed, without interruption ; scarcely deviating from the directions given, or resorting to any modification of the method laid down. Of the superior qualities of the needle I have not the slightest reason to change my opinion. It is, I am satisfied, by many degrees the best for the pur- pose. Its small size, great strength, and matchless tem- per, entitle It to a preference before all others as regards these qualities ; while its cylindrical stem and the curvature at the point, fit it for application to any peculiarity. But I find all these advantages in the instrument overlooked, if not despised, by some, because it has not the imposing ap- pearance of a finely polished blade in an» ivory or ebony 2 B 18 ON CATARACT. handle with silver ferule ; so much so, that the cutlers will not make it, or keep it for sale, and some of them have actually forged a tool to resemble it, in proportions more worthy of the trade, when called on for it by a cus- tomer. Now the truth is, that no cutler could forge, temper and finish such a blade with the slightest probabi- lity of equalling this needle, which acquires its temper by chance in the tempering of thousands of needles together. I have stated in this paper that not ten, I might perhaps have said five or six only, in a hundred of needles, are found with the temper which admits of their being bent without breaking, and enables them to preserve the set or curve given to them by the pliers. As to the strength of the blade, diminutive as it is, no fears need be entertained. I never yet broke one or saw one break in an operation ; and, as I have said, it may be passed without danger through the stoutest leather. I should, however, remind the surgeon, that the blade, before being finally pushed into the handle, should be dipped in a solution of gum lac or sealing wax, in spirit of wine, as otherwise it may rust at the wood If laid aside wet, and may snap there in con- sequence. I have also to warn those fond of " improving " surgical instruments to suit their peculiar notions, that I do not answer for the performance of any needle of this description unless it has been constructed precisely as di- rected. It must be the needle Ko. 7 (being the 44th of an inch in diameter), half an inch long in the blade, from the wood to the point, and in a cedar handle of the specified proportions. If the blade be left longer it will spring in using, and if shorter, it will not reach as far as necessary. With respect to the objection made to this operation on the score of its endangering the cornea, and causing opacity of that structure, I can with safety state that there is no- ox CATAUACT. 19 thing in it. I never yet saw vision impaired by any opacity caused by the wound of the needle, and very seldom indeed have I seen any opacity at all remain. In fact, as I have said elsewhere, I know no structure in tl\e body which bears simple injury, such as a clean cut or puncture, bet- ter than the cornea. In the course of a long practice, I have met but one case in which suppurative inflammation took place in the puncture, and in that case the suppur- ation and subsequent ulceration was confined to a circle not an eighth of an inch in diameter, and left behind an opacity not larger than the head of a pin, at a distance from the pupil, and consequently not impairing sight. I have also met with cases, but very rarely indeed, in Avhich the whole cornea suppurated, and the entire eye partici- pated in the destructive inflammation, as sometimes hap- pens from any operation for cataract ; this, however, I have never considered a consequence of the peculiar nature of the puncture in this peculiar structure, but the result of constitutional derangement operating on local inflamma- tion following injury. In fact, I looked upon it as of the same nature as the abscess of the cornea which follows very slight injury or irritable ulcer, and which takes place, not from the mere injury or ulcer, but from that state of the animal economy, whatever it may be, which is attended by these local destructive processes. But as I have said, this is a very unusual consequence of this operation ; so much so, that I have often wondered that it does not occur more frequently, seeing that it so often follows slight wounds of the cornea by particles of stone or steel in stone- cutting or metal turning. I repeat therefore emphatically that the surgeon need never be deterred from operating through the cornea by any apprehension of the effects of injury on this more than any other structure m the body he may be called upon to divide. 20 ON CATARACT. In the preceding paper and elsewhere, I have asserted the superiority of this the anterior operation through the cornea to the posterior operation through the sclerotic, and have not hesitated to say, what I now repeat, that the latter method is a disgrace to surgery, notwithstand- ing the preference given to it by many surgeons. No anatomist, aware of the nature and number of the struc- tures injured in the posterior operation, can for a moment assume that such inj ury does not cause more risk of de- structive inflammation than the injury inflicted on the cornea in the anterior one ; and no surgeon who has com- pared the effects and consequences of the two oj)erations can for a moment maintain that the results of the puncture through the sclerotic are not more injurious than those fol- lowing the puncture of the cornea. No man who knows what the penetrated structures are could venture to main- tain that the conjunctiva, sclerotic, ciliary ligament and ciliary processes, could be traversed by an instrument with the same or less injury than is inflicted in traversing the cornea ; and no man who has compared the dimensions and relations of the anterior and posterior chambers of the aqueous humour, could venture to maintain that the nar- row space behind the iris affords a more accessible passage for the needle than the comparatively capacious chamber anterior to it. Neither can any man who has witnessed the sufferings caused by this posterior operation, or the destructive consequences of the inflammation which it pro- duces, venture to assert that such mischief follows the an- terior one. The truth in fact is, that this most valuable of all the methods devised for the removal of an opaque lens has been brought into discredit and almost into disuse by this bigotted preference of a method handed down to us from a remote antiquity, when surgery was in its infancy and anatomy not yet cultivated. I have every day to ON CATARACT. 21 listen with wonder and no small vexation to the expres- sions of want of confidence in the operation for cataract, uttered, not only by patients, but by practitioners ; and this I find is to be attributed to the experience people have had of the consequences of this bad method. I know that other causes operate to diffuse and perpetuate these pre- judices and misconceptions ; that in fact they are fostered by feelings of jealousy and that spirit which leads men to decry what is successfully practised by rivals ; but the foundation of these representations is the frequent failure of this posterior operation and the sufferings patients have undergone in consequence of it. In the performance of this operation I have adopted some modifications since this paper was published. In- stead of operating on the left eye standing in front of the patient, I now operate on both eyes standing behind him. This position as regards the left eye may seem to some a strange one, but I was induced to adopt it to enable the hospital pupils to see all the steps of the operation, which they could not if I stood in front, and I now find that it is the preferable position. It gives the operator the most perfect command over the patient's head and eyelids, and enables him to bring his eye to bear on the needle and cataract with the utmost precision. Moreover, it renders him independent of an assistant who, in eye operations, should, if possible, be dispensed with. I seat the pa- tient in a chair and make him sit straight up or inclining, according to his height. If very tall I raise myself by standing on a large book or two, or on anything which an- swers the purpose to be found at hand. In my own place of business I find old medical folios answer the purpose well : operating chairs, although very imposing and cal- culated to produce effect, I have not adopted ; not finding myself at ease with such things. When he is seated I lay 22 ON CATARACT. the patient's head against my chest, and placing the middle finger of my left hand on his lower and the forefinger on his upper eyelid, and gently holding the eye between them, I strike the point of the needle suddenly into the cornea, about a line from its margin, and there hold it until any struggles of the patient, which may be made, cease. There must be no hesitation here, for if the cornea be touched without fixing the point of the needle in it, the eye will turn rapidly and the surface will be scratched. I advise the operator to pause here for a moment, holding the eye firmly and steadily on the point of his needle, and if neces- sary to say a word of encouragement or remonstrance to the patient. After quietness becomes restored, the needle is to be pushed on with a firm hand through the cornea into the anterior chamber, directing its point downward and backward to the centre of the surface of the lens. This is the most difficult step in the operation, and that part of it which requires most confidence in the instru- ment. If the surgeon now hesitates from the feel of resistance experienced he will not succeed. He must push on, fearless of consequences, until the needle passes through : in doing so, however, the eye will often turn from him or yield before the pressure, even until the pupil, iris, and the cornea itself are hidden under the eye- lid ; still he must push on until he is satisfied that the needle has fairly entered the anterior chamber, when he relaxes the pressure and allows the eye to recover its na- tural position. Here, again, he had better pause a moment to allow the patient to recover his composure, which is often disturbed in this the roughest step of the operation, and also to ascertain the distance to which the needle has passed, and how the point lies as to the margin of the pupil. If it has passed so far that the point cannot be brought into contact with the lens without touching the ON CATARACT. 23 iris, it must be gently pulled, and at the same time slightly rotated, until the point is brought within the circumfer- ence of the pupil ; and if it has passed through the iris, which sometimes happens when the pupil has not been fully dilated by belladonna, it must be gently pulled and rotated in the same way until disentangled from that structure. This, however, is a nice manoeuvre, requir- ing great delicacy of manipulation ; for if too much force be used, the needle is withdrawn entirely from the eye. Whenever this accident has happened to me, and it has been very seldom indeed, 1 have at once passed the needle in again and finished the operation ; but beginners may not be able to do all this, for the escape of some aqueous humour leaves the cornea flaccid, and therefore tough under the instrument. Some may think that this danger of wounding the iris is a capital objection to the operation, but it should not be so considered, for the ac- cident seldom happens, and when it does there is no great harm done. I have never found any mischief from it. The needle, however, having been fairly introduced, is now to be turned so as to bring the point to work on the opaque lens. If the cataract be a hard one, the surgeon must pick up the face of it by repeated delicate touches over every part of the surface ; and keeping in view the necessity of completely detaching the anterior portion of the capsule, for fear of subsequent adhesions of it to the iris and consequent capsular cataracts, he will use the needle very freely for this purpose. Here, however, he must be on his guard, for if he dips the point too deeply into a hard lens, it will stick there, and with the next motion of the instrument the cataract will be entirely detached from its bed on the vitreous humour, twirled round, and perhaps placed, through the pupil, in the an- terior chamber. Should this, however, happen, the oper- ator need not be dismayed. The same handling of the 24 ON CATARACT. needle which brought the lens into this position will bring it back again. He has only to stick the needle in it, and with a steady hand replace it in its original position : the iris, with a fully dilated pupil, offers no obstacle. In dealing with hard cataracts, I have frequently picked up the face of the lens and then turned it round and picked up the back. I know that many surgeons, and perhaps the majority of oculists or ophthalmologists, will think that all this roujrh work is a very dangerous proceeding ; but the truth is, that if the lens be kept away from the iris, so as not to press upon that highly organized and exquisitely sensible structure, the eye will bear a great deal without subsequent destructive inflam- mation. This, however, suggests an inquiry as to the final disposal of the remains of the hard lens, after all that can be broken up has been detached. Since the preceding paper was published, I have learned to dis- pose of it more advantageously than 1 then did: I force it down into the vitreous humour, and, in fact, depress or recline it, thus combining the two operations of breaking up and couching. I was for a long time adverse to the operation of depression, from a consideration of the amount of injury necessarily inflicted by tearing through the vitreous humour, and of the amount of inflammation liable to ensue from the presence of the lens, equivalent to a foreign body in that structure ; but repeated trials have convinced me that it can be done with much less danger of bad consequences than may be sup- posed. The operation of couching, notwithstanding its antiquity, must I think now rank the last of the three operations for cataract, judging from a comparison of re- sults ; but this I am inclined to think has arisen from the injudicious selection of the sclerotic as the place of punc- ture, or in other words, from the preference given to the posterior operation. Be this, however, as it may, I now ON CATARACT. 25 find that picking up, opening, and detaching, the soft sur- face of the lens, and then completely depressing the re- maining hard nucleus, is a safe and successful operation. But some will very naturally ask how it is possible to de- press a lens through the cornea with a needle half an inch long and a forty-fourth of an inch in diameter? All the reply I have to make is that it can be done very easily, and that I am constantly in the habit of doing it. As soon as the surface of a lens has been opened in texture and all the soft part detached from it, I then lay the convexity of the curve of the point of the needle upon it and force it down through and into the vitreous humour. In doing so, how- ever, this delicate needle gets entangled in it, and in with- drawing the instrument the cataract is brought up again, unless the surgeon, while the lens is down, rotates the needle a little, inclines it here and there, and as it were shakes it off the needle. But do what he will the lens will often rise as it will in any operation of depression, and must be sent down again by a repetition of the ma- noeuvre, until it remains down. Should it, however, rise after the operation has been finished, the case generally does well, because a bed has been made for it in the vitreous humour far from the iris, but recovery of sight is delayed until the solution of the cataract, which thus still, more or less, obstructs vision, takes place. I have to add, that in operating on the right eye I generally re- quire one finger of an assistant to hold down the lower lid. The value of preparatory and after-treatment as part of the surgeon's care in cataract operations has boon fully ap- preciated, and, in practice, amply made available ; but the value of a respectful consideration of all the functions of the animal economy upon which health depends has not been so well understood. It is assumed that a patient should be prepared for an operation by taking physic and c 26 ON CATARACT. abstaining from food, yet a rational man acquainted with the consecutive operation of each apparatus provided for the growth, repair, and preservation of the living being may well doubt the correctness of such a view. The uni • versal faith reposed in the practice of giving and taking physic has led practitioners not only to place too much reliance on that resource, but to resort to it sometimes to the injury of the patient, as I find in the case under con- sideration. In preparing a patient for operation, I do not act on the belief that empty bowels are essential to health, or that what are called faces should not be found in the intestinal canal ; on the contrary, I proceed on a convic- tion totally different. If a patient be in good health, not- withstanding an habitual retention of the contents of the bowels beyond the prescribed periods, I do not wish to risk an interruption of health by disturbing the natural functions of the stomach and bowels, and I therefore refrain from giving physic. But if the patient be not in good health, I of course endeavour to bring him into that con- dition by every means in my power, and resolutely resist every attempt to induce me to operate until I have accom- plished that object. Above all things, the state of the digestive organs should be carefully studied, and if found defective, if possible, repaired. Nothing seems to require more attention than the state of the tongue as indicative of the state of the stomach and bowels. If it be white or coated with discoloured adhesive mucus, the functions of assimilation and nutrition are probably imperfectly per- formed, and a resulting tendency to destructive inflamma- tion from local injury Is engendered. This I see every day exemplified in accidental Injuries of the cornea in stone- cutting, and in chipping and turning metals. If the patient has a clean tongue, and Is otherwise free from disease, little inflammation, and still less of destructive inflammation, ON CATARACT, 27 follows the injury ; but if the tongue be coated with a thick yellow adhesive layer, ulceration and formation of purulent matter often ensues. In preparing a patient for operation for cataract, this will therefore demand the first care of the surgeon ; especially if he finds, as he often does, a deposi- tion of lithates or other salts in the urine. He will also make inquiry as to the state of the discharges from the bowels, as to their colour, consistence, and proportion of undigested materials, and also as to the frequency of dis- charge ; not looking upon what is called costiveness, as evidence of deranged digestion, but rather the reverse : undigested food seldom remaining so long quiet in the alimentary canal as the insoluble remains of thoroughly digested aliment mixed with the excrementitious part of the bile. This inquiry is not, however, so easily made as those who are satisfied with loose statements suppose, and many may think it unnecessary ; but convinced as I am that attention to this matter is necessary for the success of the operation, I dwell upon it. Every practitioner has his own way of correcting this derangement of the digestive organs ; it would therefore be superfluous to enter here into details on the subject. I myself generally rely on a moderate purgative pill with blue pill or calomel at night, followed by some aromatic bitter infusion, containing a little alkaline salt, in the morning and middle of the day ; at the same time regulating the diet by restricting the quantity and quality of the food, as well as the periods at which it should be taken. It is usual in preparing for this and other operations to make great alterations in diet, substi- tuting liquid for solid, and vegetable for animal aliments. This, however, must be done with caution, leading as it inevitably does to disturbance of the digestive function and interruption of the assimilating and nutritious processes, if suddenly or exclusively adopted. Without digestible nu- 28 ON CATARACT. tritious food good chyle and blood cannot be produced, and without good blood local injuries are liable to suffer from destructive inflammation. Even in the case of old persons habitually indulging in a glass of wine or other alcoholic stimulant, the suspension of that supply of temporary aid to the nervous system should not be suddenly adopted : in fact, the substitution of " low living," and what are called " slops," for generous diet, should be gradually and spar- ingly practised, if practised at all. In my own practice, I resort to it as little as possible, and from experience feel inclined to resort to it less and less. In particular cases, the surgeon may be called on to prepare his patient for operation by special direction of remedies to specific derangements of health. Persons of languid circulation and feeble frame must be invigorated by generous diet and tonic medicines, while those of ple- thoric and bloated habit must be reduced to more suitable condition. Scrofulous or rheumatic constitution or dia- thesis must, if possible, be corrected ; and specific disease of any kind, if present, removed. All this, however, is more easily suggested than accomplished. Scrofula or rheumatism are not so easily eradicated, but it is well, with a view as much to general treatment as to prognosis of the result, that this consideration should be kept in view. When called on to operate on a truly scrofulous or rheu- matic patient, the surgeon must be careful to warn the parties concerned that the prospects of complete recovery of sight are less favourable than in cases where the health is good. The after-treatment must be conducted on the same principles as those laid down for the preparatory treatment. The tone of the stomach should be preserved, assimilation and nutrition duly maintained, and the gene- ral condition of the patient made comfortable. There is no necessity for immuring a patient after this operation in ON CATARACT. 29 a close and darkened room. The less of bed the better, and the sooner the drawing-room is made the place of con- valesence the better also. "With elderly ladies, and espe- cially those of weakly nervous system, this cannot per- haps be so soon done ; but the sooner it is done the more rapid and certain will be the recovery. Should inflamma- tion arise, it must of course be arrested, if possible, by the usual means, judiciously adjusted to the constitution and condition of the patient. Indiscriminate purging, bleeding, and mercurializing must not be permitted ; but if depletion becomes necessary, it must be carried to the requisite extent without undue severity. The surgeon should not act on the assumption, that if pain and redness be present, destructive inflammation must be in progress : the pain is generally from the pressure of fragments of the cataract on the iris, and the redness often from trivial in- flammation of the conjunctiva. Whether it be from this conviction respecting the harmless nature of slight inflam- mation and pain, or from this operation through the cornea being seldom followed by destructive inflammation, I do not find that I am often called on to draw blood either by lancet or leeches. I am now, however, alluding more to the inflammation which may come on immediately after the operation than to that which may come on at a more ad- vanced period, and which is often of more destructive cha- racter on account of its implicating the whole eyeball ; as- suming a chronic, and sometimes an intermitting, and even a neuralgic character. This inflammation must be treated as other inflammations of the eyeball, and as I have laid down in my treatise on that subject. A strange proposal has been made, probably in consequence of the frequency of destructive inflammation after the posterior operation. It has been not only suggested, but actually practised, to administer mercury to a patient previous to operation, so 2 c .■30 ON CATARACT. as to have him in a state of salivation, or on the point of salivation, at the time when inflammation is liable to come on. It is not necessary to warn the surgeon against the adoption of any such puerile application of theoretical as- sumption. Every one knows that the presence of mercury in the system does not prevent the occurrence of inflam- mation ; and the sooner every one knows that mercury is not so certain an antidote against destructive inflammation as people believe, the better. While considering the after- treatment in this operation for cataract, it is necessary to allude to an occurrence which often takes place, and which causes much distress and alarm both to patients and friends. This is a distressing nausea and vomiting which seizes the patient, generally in the middle of the night of the day of the operation, and continues for many hours, and even more or less during the next day. I attribute it to the pressure of the fragments of the broken-up lens on the iris, and find that it is not followed by destructive con- sequences ; but causing, as it does, so much distress and alarm, I generally order an opiate to be taken when it commences, or direct the attendants to be prepared with some effervescing draughts, and to assure the patient that there is nothing unusual or dangerous in the occurrence. I know not whether this remarkable effect has been ob- served by others or not, or whether it has been recorded in books, and I have not at this moment time to inquire ; but I am sure that I have always noticed it in my lectures. As to local applications, the great object of their use should be to dilate, and keep dilated, the pupil, so as to place the iris more out of the reach of the pressure of the fragments of cataract. This is, of course, to be effected by the ap- plication of extract of belladonna ; but as there seems to be some mistaken notions prevalent respecting this most valuable and remarkable agent, it may be desirable to cor- ON CATARACT. 31 rect them. The pupil is, of course, to be dilated previous to the operation to expose the lens fully and to place the iris out of reach of the needle. Some think it necessary to daub the whole eyebrow, lids, and half the cheek with the black extract, and to leave it adhering to the skin for several hours : some even lay it on the night before. This is a great waste of the medicine, and soils the skin and linen. It is astonishing what a small quantity of this most wonderful agent will dilate the pupil, especially in the eye of a young person. One grain of nitrate of atropia, dis- solved in an ounce of distilled water, will form a solution, of which one drop from a camel-hair pencil will dilate the pupil fully in fifteen, twenty, or thirty minutes : a drachm of good extract of belladonna to an ounce of water will do the same. I therefore always use these solutions in this way, putting in the drop at any time most convenient in the course of the day on which I operate. The application is neither very painful nor irritating, perhaps about as much as a weak solution of common salt, and leaves no redness after half an hour. I should observe, that in aged persons this application of the narcotic to the con- junctiva is sometimes absolutely necessary to secure full dilatation of the pupil. The smearing of the extract on the harsh skin in such subjects will not always effect the object. After the operation, however, the lids and brow should be painted with the extract to dilate the pupil and keep it dilated ; because it may not be desir- able to cause any additional irritation by dropping the solution on the conjunctiva. This is a very necessary precaution, for the surgeon should know that, however perfectly the pupil may be dilated before the operation, it generally becomes contracted again during the revo- lutions of the needle : in fact, mechanical irritation, such as the pressure of the needle or the broken fragments on 32 ON CATARACT. the iris, causes that organ to act and the pupil to return to its original dimensions. This is a remarkable physiolo- gical fact, which I have not seen recorded, but which I have for many years demonstrated in the operation theatre. By way of dressing, I leave a lotion containing a couple of drachms of good extract of belladonna in eight ounces of water to be constantly applied as a water-dressing with a small scrap of old linen as light as a feather, but I strictly interdict all tying or bandaging, and direct the attendant to allow the rag to fall off when the patient turns to sleep. It may be considered that I should state in detail the results of my practice of this operation, but as I have not been much in the habit of keeping regular records of my cases, I cannot do so. I can, however, with truth aver, that when properly performed upon healthy subjects, and patiently followed up by careful watching during the process of solution and absorption, it is an eminently suc- cessful operation. I know that the same is said of the operations of extraction and depression, but from what I have seen and heard of extraction as performed by the best operators in Europe, I have no doubt that the needle thus used will afford more cures than the knife. If it be true, as is asserted, that the losses of eyes by extraction amount to forty, thirty, or even twenty per cent., I have only to say that there should be no such loss by the operation of break- ing up through the cornea. The truth, perhaps, has never been told with respect to the result of cataract operations, and perhaps never may be told, so great is the temptation to exaggerate where a man's fame and bread depends upon his success ; but I repeat, that my experience of this oper- ation fully justifies me in asserting that it is the best of the three. As I have already said, the metropolitan oper- ator must lean to the operation of extraction because he cannot detain his patient in the city until cured by the ON CATARACT. 33 process of absorption ; but the surgeon who takes an honest interest in the welfare of his patient will probably sacrifice the chance of the eclat attending success to the greater certainty of a cure. By way of example of the results of this operation, I shall briefly enumerate a few cases which I happen to have on hands this moment. A gentleman, aged between 50 and 60 years, with a hard cataract fully formed in the left eye, and one forming in the right, has just gone to the country able to write a legible and fair letter after the operation of breaking up and depressing. He was operated on three months ago, and could see imperfectly through an open pupil after three weeks or a month, and after three weeks more could write with cataract glasses, notwithstanding occasional interruptions from a nebulous condition of the cornea caused by chronic vascularity of the conjunctiva. This gentleman had never an hour's inflammation requiring serious attention. An unmarried lady, aged about 50, had both eyes operated on ten weeks ago. The lenses were soft and were broken into a complete pulp, which fell, partly, into the anterior, and partly, into the posterior chamber of the aqueous humour. There was severe nausea and vomiting the night following the operation, and some pain occasionally as the fragments fell against the iris, but no inflammation. She is now able to read and write with a cataract glass to the left eye, the pupil of which is entirely free from cataract. In the right eye there is still as much broken up lens as fills up the space behind the pupil, but it is rapidly dis- solving, and I am satisfied that she will require no re- petition of the operation. About eight weeks ago I oper- ated on a young gentleman for capsular cataract, the result of a penetrating wound of the eye Inflicted a long time since. He is aged about 12, and sat in a common chair while I operated with a shawl tied round his arms, body. 34 ox CATAKACT. and the back of the chair. The capsule, with some re- maining portion of the lens, was freely torn and detached, and the child sent home. He continued to attend daily, not the slightest inflammation following, but was attacked by scarlatina, which nearly terminated fatally. His pupil is now nearly free from broken lens, and I consider him safe as to his vision. In the hospital I operated on a deli- cate boy, aged 1 4, and five years blind with soft lenticular and partially opaque capsular cataracts. The operation was performed two months ago, the capsules freely torn and detached, and the lenses made into a pulp. He had nausea and vomiting, but no inflammation after the opera- tion. His pupils are now completely clear, and he is able to walk about without glasses and to read with them. A labouring man, aged 37, was operated on for soft lenticular cataract of the right eye about twelve weeks since. He had lost the left eye from a blow of a stone, and I suspect his cataract in the other eye was caused by sympathetic in- flammation. Notwithstanding the difficulties presented by a small sunk eye, very difficult to be brought to a steady state, the lens was freely opened and a hard nucleus of it depressed. The pupil was soon clear, but the remainder of the hard nucleus, still undissolved, rose with the mo- tion of the head occasionally towards the axis of vision : it, however, finally dissolved without any other opera- tion, and he now sees well with it about twelve weeks after the operation. A girl, aged 17, operated on about three weeks ago for thick and tough capsular cat-a- ract of the right eye, has now an open pupil, but she cannot see. I was induced to give her the chance of an operation by the importunities of her friends, which I should not have done, because it was a case of opaque lenses with adherent pupils and other proofs of previous destruc- tive inflammation ; but I was tempted to do so from the ON CATARACT. 35 state of the eye, the pupil being closed by capsular cataract only, remaining after an operation by another surgeon. Notwithstanding, however, the disorganized state of this eye from the previous destructive inflammation, no inflam- mation followed the operation ; and if the retina had not been rendered insensible, and the eye consequently amau- rotic by the same disease which caused the cataracts, she might now have good sight. The worst case I have on hands is that of a man, aged about 35, who had lenticular cataracts of the firm consistence (neither hard nor soft) usually found at this period of life. The operation was performed on both eyes about six months ago, and was not followed by any untoward symptom, but some weeks after he had a severe attack of acute rheumatism, fol- lowed by severe rheumatic inflammation of the left eye, which closed the pupil j and he subsequently suffered severely from psoriasis, from which he is now scarcely recovered. The pupil of the right eye is, however, free from cataract, except some threads of opaque capsule, which I propose to remove ; and the left eye looks so well that I intend to give him the chance of an opera- tion for artificial pupil on it. From these cases the surgeon can form some opinion as to the practical re- sults of this operation. They present the general effects of the practice, and certainly do not afford more favour- able examples than an average would supply. I have no wish to indulge in any exaggeration respecting the success of this method: I am writing for surgeons, who will, in the sequel, pronounce a verdict upon it from their own ex- perience, and thereby verify or disprove my statements. Malicious persons will say that I advocate this operation because I cannot perform that of extraction as easily ; but I can perform extraction as well as other people, and refrain from it only because it is in its nature 36 ON CATARACT. a most formidable operation, and in its results a most hazardous one. In principle, too, it is not creditable to surgery. To cut open a man's eye, in order to squeeze out his crystalline lens through the incision, when that lens can be removed by absorption, I hold to be contrary to the rule which binds the surgeon to give his patient the best chance of recovery regardless of present inconvenience or delay. But whatever view may be entertained on this subject, I am firmly convinced that the operation of extrac- . tion should be restricted to hard cataracts in aged persons. Under fifty years of age, the crystalline lens once broken in pieces, must be sooner or later dissolved and absorbed. There can be no question as to the result ; it is only a question as to time. DUBLIN: PRINTED AT THE MEDICAL PRESS OFFICE. 'V ^ UNIVERSITY OF CALIFORNIA LIBRARY Los Angeles This book is DUE on the last date stamped below. wojB'fft- Form L9-40m-5;67(H2161s8)4939 dF -ife'"™ >: J ^^1 i^r ■ W|« ^ I 'Ja T^ ■ Mi >H ''Ji m iliili