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Al? No. 88-14
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PUBL
| NATIONAL LIBRARY of MEDICINE
Sjogren’s Syndrome
January 1985 through December 1988
185 Citations
Prepared by Karen Patrias, Philip C. Fox, Stephen P. Heyse
70 C70
(Voomnbarn d
RC
U. S. DEPARTMENT OF HEALTH AND HUMAN SERVICES ; é ¥ 7
Public Health Service aS
National Institutes of Health 85
U.S. DEPOSITORY A/2
JAN 2 6 1989 3

PUBL
''PUBLIC HEALTH LIBRARY.

  
 
 
  

BERKEL fy \
\

LIBRARY
UNIVERSITY OF
CALIFORNIA
''CBM No. 88-14

Sjogren’s Syndrome

January 1985 through December 1988

185 Citations

Prepared by
Karen Patrias, M.L.S., National Library of Medicine
Philip C. Fox, D.D.S., National Institute of Dental Research

Stephen P. Heyse, M.D., M.P.H., National Institute of Arthritis and Musculoskeletal
and Skin Diseases

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AND HUMAN SERVICES

Public Health Service

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''arte

SJOGREN’S SYNDROME

Sjogren’s syndrome is a chronic inflammatory disease characterized by destruction and inflammation
of the exocrine glands. The salivary and lachrymal glands are principally involved, giving rise to dry
eyes and mouth, although other glands may be affected. The disease is most commonly seen as a
slowly progressive development of diminished glandular secretion in patients with rheumatoid
arthritis or other autoimmune disease or the more rapid development of a severe oral and ocular
dryness, often accompanied by episodic parotitis, in an otherwise well patient.

Though sometimes described as the second most common autoimmune rheumatic disease, the exact
prevalance of the disease is unknown. Some people have symptoms that are so mild that they do not
seek medical advice; and there are others who complain of symptoms but in whom the disorder is not
recognized and identified.

This bibliography was prepared in support of the conference "The Many Faces of Sjogren’s
Syndrome" held at the National Institutes of Health in Bethesda, Maryland, on January 18-19, 1989.
The conference was intended as a state-of-the-art review directed primarily toward practicing
physicians, dentists, and other health professionals. The purpose was to communicate the latest
understanding of several aspects of Sjogren’s syndrome, including its diverse clinical picture and its
diagnosis and treatment. This bibliography focuses on three major areas: incidence and prevalence,
clinical manifestations and diagnosis, and treatment and management. It consists primarily of journal
articles published since January 1985. Specifically omitted were items dealing primarily with
immunology and pathology, pure research, foreign language material, and letters.

5 Anks

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5

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19 %8
PURL
''SEARCH STRATEGY

A variety of online databases are usually searched in preparing bibliographies in the CBM series. To
assist you in updating or otherwise manipulating the material in this search, the strategy used for the
NLM’s MEDLINE database is given below. Please note that the search strategies presented here
differ from individual demand searches in that they are generally broadly formulated and irrelevant
citations edited out prior to printing.

SS 1 = SUBS APPLY DI, CO, DH, DT, TH, RT, SU, RH, OC

SS 1 = SJOGREN’S SYNDROME OR XEROSTOMIA OR XEROPHTHALMIA OR
KERATOCONJUNCTIVITIS SICCA

SS 2 = SUBS CANCEL

SS 2 = SJOGREN’S SYNDROME OR XEROSTOMIA OR XEROPHTHALMIA OR
KERATOCONJUNCTIVITIS SICCA

SS 3 = 2 AND REVIEW
SS 4=10R3
SS 5 = 4 AND NOT LETTER (TW)

SS 6 = 5 AND NOT FOR
''SAMPLE CITATIONS

Citations in this bibliographic series are formatted according to the rules established for Index
Medicus. Sample journal and monograph citations appear below. Note also that a colon (:) may
appear within an author’s name. The NLM computer system automatically inserts this symbol in the
place of a diacritical mark.

Journal Article:

Authors . Article Title

“_
Binder A ; Snaith ML ; Isenberg D. Sjogren’s syndrome: a study of its neurological
manifestations. Br J Rheumatol 1988 Aug;27(4):275-80
\

Abbreviated Journal Date Volume Issue Pages
Title
Monograph:
Authors/Editors Title

Talal, Norman ; Moutsopulos, H.M. ; Kassan, S.S., editors. Sjogren’s syndrome: clinical and
immunological aspects. New York: aa 1987. 299p.
/

Place of Publisher Date No. of Pages
Publication
''''TABLE OF CONTENTS

page

Incidence and Prevalence
Clinical Manifestations and Diagnosis
Treatment and Management

ON ke
''''INCIDENCE AND PREVALENCE

Reviews/Comprehensive Articles

Ben-Aryeh H ; Miron D ; Berdicevsky I ; Szargel R ;
Gutman D. Xerostomia in the elderly: prevalence,
diagnosis, complications and treatment.
Gerodontology 1985 Winter;4(2):77-82

Others

Andonopoulos AP ; Drosos AA ; Skopouli FN ;
Acritidis NC ; Moutsopoulos HM. Secondary
Sjogren’s syndrome in rheumatoid arthritis.

J Rheumatol 1987 Dec;14(6):1098-103

Coll J ; Rives A ; Gri~no MC ; Setoain J ; Vivancos J ;
Balcells A. Prevalence of Sjogren’s syndrome in
autoimmune diseases. Ann Rheum Dis 1987 Apr;
46(4):286-9

Drosos AA ; Andonopoulos AP ; Costopoulos JS ;
Papadimitriou CS ; Moutsopoulos HM. Prevalence
of primary Sjogren’s syndrome in an elderly
population. Br J Rheumatol 1988 Apr;27(2):123-7

Indirabai K ; Bhatt JV ; Vaidyanathan K.
Epidemiological survey for prevalence of
xerophthalmia. Indian Pediatr 1986 Feb;23(2):135-9

Mody GM ; Hill JC ; Meyers OL. Keratoconjunctivitis
sicca in rheumatoid arthritis. Clin Rheumatol 1988
Jun;7(2):237-41

Strickland RW ; Tesar JT ; Berne BH ; Hobbs BR ;
Lewis DM ; Welton RC. The frequency of sicca
syndrome in an elderly female population.

J Rheumatol 1987 Aug; 14(4):766-71
''CLINICAL MANIFESTATIONS AND
DIAGNOSIS

Reviews/Comprehensive Articles

Alexander EL. Central nervous system (CNS)
manifestations of primary Sjogren’s syndrome: an
overview. Scand J Rheumatol [Suppl] 1986;61:161-5

Alexander M. Clinical aspects of Sjogren’s syndrome.
South Med J 1986 Jul;79(7):857-62

Bajart AM. Common eye problems in the older
woman. Women Health 1985 Summer-Fall;10(2-3):
85-93

Baum J. Clinical manifestations of dry eye states.
Trans Ophthalmol Soc UK 1985;104(Pt 4):415-23

Ben-Aryeh H ; Miron D ; Berdicevsky I ; Szargel R ;
Gutman D. Xerostomia in the elderly: prevalence,
diagnosis, complications and treatment.
Gerodontology 1985 Winter;4(2):77-82

Fox RI ; Michelson PE ; Howell FV. Ocular and oral
problems in arthritis. How to recognize, when to
refer. Postgrad Med 1985 Sep 1;78(3):87-93, 96-7

McMonnies CW. Key questions in a dry eye history.
J Am Optom Assoc 1986 Jul;57(7):512-7

Provost TT ; Vasily D ; Alexander E. Sjogren’s
syndrome. Cutaneous, immunologic, and nervous
system manifestations. Neurol Clin 1987 Aug;5(3):
405-26

Scully C. Sjogren’s syndrome: clinical and laboratory
features, immunopathogenesis, and management.
Oral Surg Oral Med Oral Pathol 1986 Nov;62(5):
510-23

Smith DL ; Lucas LM. Sjogren’s syndrome. More than
dry eyes and dry mouth. Postgrad Med 1987 Jul;
82(1):123-31

Standefer JA Jr ; Mattox DE. Head and neck
manifestations of collagen vascular diseases.
Otolaryngol Clin North Am 1986 Feb;19(1):181-210

Talal N. Overview of Sjogren’s syndrome. J Dent Res
1987 Feb;66 Spec No:672-4

Talal, Norman ; Moutsopoulos, H. M. ; Kassan, S. S.,
editors. Sjogren’s syndrome: clinical and
immunological aspects. New York: Springer-Verlag,
1987. 299p.

Whitcher JP. Clinical diagnosis of the dry eye. Int
Ophthalmol Clin 1987 Spring;27(1):7-24

Others

Alexander E ; Provost TT. Sjogren’s syndrome.
Association of cutaneous vasculitis with central
nervous system disease. Arch Dermatol 1987 Jun;
123(6):801-10

Alexander EL ; Beall SS ; Gordon B ; Selnes OA ;
Yannakakis GD ; Patronas N ; Provost TT;
McFarland HF. Magnetic resonance imaging of
cerebral lesions in patients with the Sjogren
syndrome. Ann Intern Med 1988 Jun;108(6):815-23

Alexander EL ; Lijewski JE ; Jerdan MS ; Alexander
GE. Evidence of an immunopathogenic basis for
central nervous system disease in primary Sjogren’s
syndrome. Arthritis Rheum 1986 Oct;29(10):1223-
31

Alexander EL ; Malinow K ; Lejewski JE ; Jerdan MS ;
Provost TT ; Alexander GE. Primary Sjogren’s
syndrome with central nervous system disease
mimicking multiple sclerosis. Ann Intern Med 1986
Mar;104(3):323-30

Alkhayer M ; McCann BG ; Harrison BDW.
Lymphocytic interstitial pneumonitis in association
with Sjogren’s syndrome. Br J Dis Chest 1988;82(3):
305-9
''Andonopoulos AP ; Karadanas AH ; Drosos AA ;
Acritidis NC ; Katsiotis P ; Moutsopoulos HM. CT
evaluation of mediastinal lymph nodes in primary
Sjogren syndrome. J Comput Assist Tomogr 1988
Mar-Apr;12(2):199-201

Arentsen JJ. The dry eye. J Ophthalmic Nurs Technol
1987 Jul-Aug;6(4):134-7

Arrago JP ; Rain JD ; Brocheriou C ; Rocher F.
Scintigraphy of the salivary glands in Sjogen’s
syndrome. J Clin Pathol 1987;40(12):1463-7

Batsakis JG. Lymphoepithelial lesion and Sjogren’s
syndrome. Ann Otol Rhinol Laryngol 1987 May-
Jun;96(3 Pt 1):354-5

Berta A ; Torok M. Tear glycoprotein determinations
in the diagnosis and differential diagnosis of dry
eyes. Scand J Rheumatol [Suppl] 1986;61:228-33

Binder A ; Snaith ML ; Isenberg D. Sjogren’s
syndrome: a study of its neurological complications.
Br J Rheumatol 1988 Aug;27(4):275-80

Boersma HG ; van Bijsterveld OP. The lactoferrin test
for the diagnosis of keratoconjunctivitis sicca in
clinical practice. Ann Ophthalmol 1987 Apr;19(4):
152-4

Bone RC ; Fox RI ; Howell FV ; Fantozzi R. Sjogren’s
syndrome: a persistent clinical problem.
Laryngoscope 1985 Mar;95(3):295-9

Capriello P ; Barale E ; Cappelli N ; Lupo S ; Teti G.
Sjogren’s syndrome: clinical, cytological, histological
and colposcopic aspects in women. Clin Exp Obstet
Gynecol 1988;15(1-2):9-12

Constantopoulos SH ; Moutsopoulos HM.
Respiratory involvement in patients with Sjogren’s
syndrome: is it a problem? Scand J Rheumatol
[Suppl] 1986;61:146-50

Constantopoulos SH ; Papadimitriou CS ;
Moutsopoulos HM. Respiratory manifestations in
primary Sjogren’s syndrome. A clinical, functional,
and histologic study. Chest 1985 Aug;88(2):226-9

Daniels TE. Salivary histopathology in diagnosis of
Sjogren’s syndrome. Scand J Rheumatol [Supp!]
1986;61:36-43

Davis CC ; Marks JE. The use of the Schirmer tear
test in evaluating mouth dryness. Dent Hyg (Chic)
1986 Mar;60(3):116-9, 129

de Clerck LS ; Couttenye MM ; de Broe ME ; Stevens
WJ. Acquired immunodeficiency syndrome
mimicking Sjogren’s syndrome and systemic lupus
erythematosus. Arthritis Rheum 1988 Feb;31(2):
272-5

de Wilde PC ; Baak JP ; Slootweg PJ ; Hene RJ ; Kater
L. Morphometry in the diagnosis of Sjogren’s
syndrome. Anal Quant Cytol Histol 1986 Mar;8(1):
49-55

Drosos AA ; Andonopoulos AP ; Costopoulos JS ;
Papadimitriou CS ; Moutsopoulos HM. Prevalence
of primary Sjogren’s syndrome in an elderly
population. Br J Rheumatol 1988 Apr;27(2):123-7

Drosos AA ; Andonopoulos AP ; Costopoulos JS ;
Stavropoulos ED ; Papadimitriou CS ;
Moutsopoulos HM. Sjogren’s syndrome in
progressive systemic sclerosis. J Rheumatol 1988
Jun;15(6):965-8

Falkoff RJ ; Schatz M. Nasal manifestations of
systemic immunologic disorders. Ear Nose Throat J
1986 May;65(5):231-4

Farris RL ; Gilbard JP ; Stuchell RN ; Mandel ID.
Diagnostic tests in keratoconjunctivitis sicca.
CLAO J 1983 Jan-Mar;9(1):23-8

Farris RL ; Stuchell RN ; Mandel ID. Tear osmolarity
variation in the dry eye. Trans Am Ophthalmol Soc
1986;84:250-68

Ferreiro JE ; Pasarin G ; Quesada R ; Gould E.
Benign hypergammaglobulinemic purpura of
Waldenstrom associated with Sjogren’s syndrome.
Case report and review of immunologic aspects.
Am J Med 1986 Oct;81(4):734-40
''Fox PC ; Busch KA ; Baum BJ. Subjective reports of
xerostomia and objective measures of salivary gland
performance. J Am Dent Assoc 1987 Oct;115(4):
581-4

Fox PC ; van der Ven PF ; Sonies BC ; Weiffenbach
JM ; Baum BJ. Xerostomia: evaluation of a
symptom with increasing significance. J Am Dent
Assoc 1985 Apr;110(4):519-25

Franklin DJ ; Smith RJ ; Person DA. Sjogren’s
syndrome in children. Otolaryngol Head Neck Surg
1986 Feb;94(2):230-5

Friberg B ; Jonsson R ; Linde A. Salivary kallikrein in
Sjogren’s syndrome. Clin Exp Rheumatol 1988;6(2):
135-8

Gardner KM ; Rajacich GM ; Mondino BJ.
Ophthalmological manifestations of adult
rheumatoid arthritis and cicatricial pemphigoid.
Int Ophthalmol Clin 1985 Spring;25(1):1-35

Halken P ; B|g-Hansen TC ; Prause JU. Differences
between glycoprotein profiles of normal tear fluid
and of tear fluid from patients with primary
Sjogren’s syndrome. Scand J Rheumatol [Suppl]
1986;61:234-6

Hatron PY ; Wallaert B ; Gosset D ; Tonnel AB;
Gosselin B ; Voisin C ; Devulder B. Subclinical lung
inflammation in primary Sjogren’s syndrome.
Relationship between bronchoalveolar lavage
cellular analysis findings and characteristics of the
disease. Arthritis Rheum 1987 Nov;30(11):1226-31

Healey LA. Rheumatoid arthritis in the elderly. Clin
Rheum Dis 1986 Apr;12(1):173-9

Holly FJ. Dry eye and the Sjogren’s syndrome. Scand J
Rheumatol [Suppl] 1986;61:201-5

Hostein J ; Fournet J. Gastrointestinal manifestations
of collagen diseases. Dig Dis 1986;4(4):240-52

James DG ; Sharma OP. Overlap syndromes with
sarcoidosis. Sarcoidosis 1985 Sep;2(2):116-21

Janssen PT ; van Bijsterveld OP. Tear fluid proteins in
Sjogren’s syndrome. Scand J Rheumatol [Suppl]
1986;61:224-7

Kjellen G ; Fransson SG ; Lindstrom F ; Sokjer H ;
Tibbling L. Esophageal function, radiography, and
dysphagia in Sjogren’s syndrome. Dig Dis Sci 1986
Mar;31(3):225-9

Kohler PF ; Winter ME. A quantitative test for
xerostomia. The Saxon test, an oral equivalent of the
Schirmer test. Arthritis Rheum 1985 Oct;28(10):
1128-32

Kraus A ; Alarcon-Segovia D. Primary juvenile
Sjogren’s syndrome. J Rheumatol 1988;15(5):803-6

Kraus A ; Cervantes G ; Barojas E ; Alarc:on Segovia
D. Retinal vasculitis in mixed connective tissue
disease. A fluoroangiographic study. J Rheumatol
1985 Dec;12(6):1122-4

Lemp MA ; Mahmood MA ; Weiler HH. Association
of rosacea and keratoconjunctivitis sicca. Arch
Ophthalmol 1984 Apr;102(4):556-7

Lindvall AM ; Jonsson R. The salivary gland
component of Sjogren’s syndrome: an evaluation of
diagnostic methods. Oral Surg Oral Med Oral
Pathol 1986 Jul;62(1):32-42

Mackie IA ; Seal DV. Confirmatory tests for the dry
eye of Sjogren’s syndrome. Scand J Rheumatol
[Suppl] 1986;61:220-3

Mackor AJ ; Van Bijsterveld OP. Tear function
parameters in keratoconjunctivitis sicca with and

without the association of Sjogren’s syndrome.
Ophthalmologica 1988;196(4):169-74

Malinow KL ; Molina R ; Gordon B; Selnes OA ;
Provost TT ; Alexander EL. Neuropsychiatric
dysfunction in primary Sjogren’s syndrome. Ann
Intern Med 1985 Sep;103(3):344-50

Malmstrom MJ ; Segerberg-Konttinen M ; Tuominen
TS ; Hietanen JH ; Wolf JE ; Sane JI ; Konttinen
YT. Xerostomia due to Sjogren’s syndrome.
Diagnostic criteria, treatment and outlines for a
'') continuous dental care programme and an open
trial with Sulfarlem. Scand J Rheumatol 1988;
17(2):77-86

Manoussakis MN ; Tzioufas AG ; Pange PJ ;
Moutsopoulos HM. Serological profiles in
subgroups of patients with Sjogren’s syndrome.
Scand J Rheumatol [Suppl] 1986;61:89-92

Maran AG. Sjogren’s syndrome. J Laryngol Otol 1986 |

Nov;100(11):1299-305

Marx RE ; Hartman KS ; Rethman KV. A prospective
study comparing incisional labial to incisional
parotid biopsied in the detection and confirmation
of sarcoidosis, Sjogren’s disease, sialosis and
lymphoma. J Rheumatol 1988;15(4):621-9

McLaughlin WS. Sjogren’s syndrome and juvenile
rheumatoid arthritis. Proc Br Soc Dent Maxillofac
Radiol 1986;(1):17-21

McMonnies CW ; Ho A. Patient history in screening
for dry eye conditions. J Am Optom Assoc 1987
Apr;58(4):296-301

McMonnies CW ; Ho A. Responses to a dry eye
questionnaire from a normal population. J Am
Optom Assoc 1987 Jul;58(7):588-91

Mengher LS ; Pandher KS ; Bron AJ. Non-invasive
tear film break-up time: sensitivity and specificity.
Acta Ophthalmol (Copenh) 1986 Aug;64(4):441-4

Mitchell J ; Greenspan J ; Daniels T ; Whitcher JP ;
Maibach HI. Anhidrosis (hypohidrosis) in Sjogren’s
syndrome. J Am Acad Dermatol 1987 Jan;16(1 Pt
2):233-5

Mody GM ; Hill JC ; Meyers OL. Keratoconjunctivitis
sicca in rheumatoid arthritis. Clin Rheumatol 1988
Jun;7(2):237-41

Molina R ; Provost TT ; Alexander EL. Peripheral
inflammatory vascular disease in Sjogren’s
syndrome. Association with nervous system
complications. Arthritis Rheum 1985 Dec;28(12):
1341-7

Molina R ; Provost TT ; Arnett FC ; Bias WB ;
Hochberg MC ; Wilson RW ; Alexander EL.
Primary Sjogren’s syndrome in men. Clinical,
serologic, and immunogenetic features. Am J Med
1986 Jan;80(1):23-31

Moutsopoulos HM ; Andonopoulos AP. Sjogren’s
syndrome: a human model of autoimmunity and
malignancy. Br J Rheumatol 1988 Aug;27(4):253-7

Oribe K. Pancreatic lesions in Sjogren’s syndrome.
Fukuoka Acta Med 1985;76(3):55-66

Ormerod LD ; Fong LP ; Foster CS. Corneal infection
in mucosal scarring disorders and Sjogren’s
syndrome. Am J Ophthalmol 1988 May 15;105(5):
512-8

Oxholm P ; Manthorpe R ; Oxholm A ; Schildt M.
Immunoglobulin deposits in labial mucosal
epithelium of patients suspected of Sjogren’s
syndrome. Eur J Clin Invest 1986 Feb;16(1):91-6

Oxholm P ; Oxholm A ; Manthorpe R. Epidermal IgG
deposits in patients with chronic inflammatory
connective tissue diseases: diagnostic value and
correlation to clinical and immunological
parameters in patients with primary Sjogren’s
syndrome. Clin Exp Rheumatol 1987 Jan-Mar;
5(1):5-9

Oxholm P ; Winther K. Platelet involvement in
salivary gland inflammation in patients with primary
Sjogren’s syndrome. Rheumatol Int 1987;7(1):29-33

Pal B ; Griffiths ID ; Katrak A ; et al. Salivary amylase
and pancreatic enzymes in Sjogren’s syndrome. Clin
Chem 1987;33(2):305-7

Papathanasiou MP ; Constantopoulos SH ;
Tsampoulas C ; Drosos AA ; Moutsopoulos HM.
Reappraisal of respiratory abnormalities in primary
and secondary Sjogren’s syndrome. A controlled
study. Chest 1986 Sep;90(3):370-4

Parikh PK. The sicca (Sjogren’s) syndrome. Ear Nose
Throat J 1987 Nov;66(11):449-53
''Raphael M ; Bellefqih S ; Piette JC ; Le Hoang P ;
Debre P ; Chomette G. Conjunctival biopsy in
Sjogren’s syndrome: Correlations between
histological and immunohistochemical features.
Histopathology 1988;13(2):191-202

Rhodus NL. Detection and management of the dental
patient with Sjogren’s syndrome. Compendium 1987
Sep;8(8):578, 580, 582 passim

Rolando M ; Baldi F ; Zingirian M. The effect of
hyperosmolarity on tear mucus ferning. Fortschr
Ophthalmol 1986;83(6):644-6

Rosenbaum JT ; Bennett RM. Chronic anterior and
posterior uveitis and primary Sjogren’s syndrome.
Am J Ophthalmol 1987 Oct 15;104(4):346-52

Sargent C ; Ludlow M ; McCredie M ; Brooks PM ;
Webb J. Assessment of a patient-completed
questionnaire for keratoconjunctivitis sicca. Med J
Aust 1988 Apr 18;148(8):395-8

Schiodt M ; Daniels TE ; Greenspan JS ; Oxholm P ;
Prause JU ; Manthorpe-R. Comparing diagnostic
criteria for the salivary component of Sjogren’s
syndrome. Scand J Rheumatol [Suppl] 1986;61:44-6

Segerberg-Konttinen M. Focus score in sialolithiasis.
A pitfall in differential diagnosis of Sjogren’s
syndrome. Scand J Rheumatol 1988;17(2):87-9

Shanahan F ; Stack J ; Maguire S ; Crowe J. The
pancreas, primary biliary cirrhosis and the dry gland
syndrome. Ir J Med Sci 1985 Oct;154(10):387-9

Shiozawa S ; Shiozawa K ; Shimizu S ; Nakada M ;
Isobe T ; Fujita T. Clinical studies of renal disease
in Sjogren’s syndrome. Ann Rheum Dis 1987 Oct;
46(10):768-72

Siamopoulos KC ; Mavridis AK ; Elisaf M ; Drosos
AA ; Moutsopoulos HM. Kidney involvement in
primary Sjogren’s syndrome. Scand J Rheumatol
[Suppl] 1986;61:156-60

Speransky AI ; Ivanova MI ; Rjazantceva TA ; Piven
VA ; Bulanova TD. Antinuclear antibodies in lupus
erythematosus and Sjogren’s syndrome: Clinical and

immunological investigations. Scand J Rheumatol
[Suppl] 1988;67:39-43

Sreebny LM ; Valdini A. Xerostomia. A neglected
symptom. Arch Intern Med 1987 Jul;147(7):1333-7

Stevens MB. Connective tissue disease in the elderly.
Clin Rheum Dis 1986 Apr;12(1):11-32

Sugai S ; Shimizu S ; Konda S. Lymphoproliferative
disorders in Japanese patients with Sjogren’s
syndrome. Scand J Rheumatol [Suppl] 1986;61:118-
22

Sugai S ; Shimizu S ; Tachibana J ; Sawada M ; Hirose
Y ; Takiguchi T ; Konda S. Monoclonal
gammopathies in patients with Sjogren’s syndrome.
Jpn J Med 1988 Feb;27(1):2-9

Sugai S ; Tachibana J ; Sawada M ; Shimizu S ; Hirose
Y ; Takiguchi T ; Konda S. Malignant lymphomas
in patients with autoimmune diseases: a report of 6
cases and a review of the Japanese literature. Jpn J
Med 1987 Aug;26(3):339-47

Sugai S ; Takiguchi T ; Hirose Y ; Shimizu S ;
Tachibana J ; Konda S ; Konishi F. B cell malignant
lymphoma in a patient with progressive systemic
sclerosis and Sjogren’s syndrome. Report of a case
and review of the literature. Jpn J Med 1985 May;
24(2):155-63

Sugihara T ; Yoshimura Y. Scintigraphic evaluation of
the salivary glands in patients with Sjogren’s
syndrome. Int J Oral Maxillofac Surg 1988 Apr;
17(2):71-5

Swaak AJ ; Visch LL ; Zonneveld A. Diagnostic
significance of salivary levels of beta 2-microglobulin
in Sjogren’s syndrome. Clin Rheumatol 1988 Mar;
7(1):28-34

Talal N. Sjogren syndrome and pseudolymphoma.
Hosp Pract [Off] 1988 Sep 30;23(9A):71-5, 78-80

Tarail J. Sjogren’s syndrome. A dry-eyed diary. Am J
Nurs 1987 Mar;87(3):324-6
''Thorn JJ ; Oxholm P ; Andersen HK. High levels of
complement fixing antibodies against
cytomegalovirus in patients with primary Sjogren’s
syndrome. Clin Exp Rheumatol 1988;6(1):71-4

Tsampoulas CG ; Skopouli FN ; Sartoris DJ ; Kaplan
P ; Kursunoglu S ; Pineda C ; Resnick D ;
Moutsopoulos HM. Hand radiographic changes in
patients with primary and secondary Sjogren’s
syndrome. Scand J Rheumatol 1986;15(3):333-9

Tsianos EB ; Vasakos S ; Drosos AA ; Malamou-Mitsi
VD ; Moutsopoulos HM. The gastrointestinal
involvement in primary Sjogren’s syndrome. Scand J
Rheumatol [Suppl] 1986;61:151-5

Tsokos M ; Lazarou SA ; Moutsopoulos HM.
Vasculitis in primary Sjogren’s syndrome. Histologic
classification and clinical presentation. Am J Clin
Pathol 1987 Jul;88(1):26-31

Tzioufas AG ; Manoussakis MN ; Costello R ; Silis M ;
Papadopoulos NM ; Moutsopoulos HM.
Cryoglobulinemia in autoimmune rheumatic
diseases. Evidence of circulating monoclonal
cryoglobulins in patients with primary Sjogren’s
syndrome. Arthritis Rheum 1986 Sep;29(9):1098-
104

Ulirsch RC ; Jaffe ES. Sjogren’s syndrome-like illness
associated with the acquired immunodeficiency
syndrome-related complex. Hum Pathol 1987 Oct;
18(10):1063-8

Vermylen C ; Meurant A ; No:el H ; Claus D ; Cornu
G. Sjogren’s syndrome in a child. Eur J Pediatr
1985 Sep;144(3):266-9

Vitali C ; Tavoni A ; Simi U ; Marchetti G ; Vigorito
P ; d’Ascanio A ; Neri R ; Cristofani R ;
Bombardieri S. Parotid sialography and minor
salivary gland biopsy in the diagnosis of Sjogren’s
syndrome. A comparative study of 84 patients.

J Rheumatol 1988 Feb;15(2):262-7

Vitali C ; Tavoni A ; Viegi G ; Begliomini E ; Agnesi
A ; Bombardieri S. Lung involvement in Sjogren’s
syndrome: a comparison between patients with
primary and with secondary syndrome. Ann Rheum
Dis 1985 Jul;44(7):455-61

Vrielinck LJG ; Van Parys G ; Van Damme B ;
Bossuyt M. Sicca syndrome with iron deposition in
the salivary glands. Int J Oral Maxillofac Surg 1988;
17(1):11-3

Waldenstrom J. Hyperglobulinemic purpura, chronic
sialoadenitis and the Sjogren syndrome. Scand J
Rheumatol [Suppl] 1986;61:139-41

Wallaert B ; Prin L ; Hatron PY ; Ramon P ; Tonnel
AB; Voisin C. Lymphocyte subpopulations in
bronchoalveolar lavage in Sjogren’s syndrome:
Evidence for an expansion of cytotoxic/suppressor
subset in patients with alveolar neutrophilia. Chest
1987;92(6):1025-31

Walters MT ; Stevenson FK ; Herbert A ; Cawley MI ;
Smith JL. Lymphoma in Sjogren’s syndrome:
urinary monoclonal free light chains as a diagnostic
aid and a means of tumour monitoring. Scand J
Rheumatol [Suppl] 1986;61:114-7

Walters MT ; Stevenson FK ; Herbert A ; Cawley MI ;
Smith JL. Urinary monoclonal free light chains in
primary Sjogren’s syndrome: an aid to the diagnosis
of malignant lymphoma. Ann Rheum Dis 1986 Mar;
45(3):210-9

Welch C ; Baum J. Tarsorrhaphy for corneal disease in
patients with rheumatoid arthritis. Ophthalmic Surg
1988 Jan;19(1):31-2

White RH. Preoperative evaluation of patients with
rheumatoid arthritis. Semin Arthritis Rheum 1985
May;14(4):287-99

Whitehead EM ; Daly JG ; Hayes JR. Renal tubular
acidosis in association with Sjogren’s syndrome,
primary biliary cirrhosis and coeliac disease. Ir J
Med Sci 1987 Apr;156(4):124-5

Whittingham §S ; Naselli G ; McNeilage LJ ; Coppel
RL ; Sturgess AD. Serological diagnosis of primary
Sjogren’s syndrome by means of human
recombinant La (SS-B) as nuclear antigen. Lancet
1987 Jul 4;2(8549):1-3
''Willis RM ; Folberg R ; Krachmer JH ; Holland EJ.
The treatment of aqueous-deficient dry eye with
removable punctal plugs. A clinical and impression-
cytologic study. Ophthalmology 1987 May;94(5):
514-8

Wise CM ; Agudelo CA. Optic neuropathy as an initial
manifestation of Sjogren’s syndrome. J Rheumatol
1988;15(5):799-802

Wise CM ; Agudelo CA ; Semble EL ; Stump TE ;
Woodruff RD. Comparison of parotid and minor
salivary gland biopsy specimens in the diagnosis of
Sjogren’s syndrome. Arthritis Rheum 1988 May;
31(5):662-6

Wittpenn JR ; Tseng SC ; Sommer A. Detection of
early xerophthalmia by impression cytology. Arch
Ophthalmol 1986 Feb;104(2):237-9

Yamaoka K ; Miyasaka N ; Yamamoto K. Possible
involvement of Epstein-Barr virus in polyclonal B
cell activation in Sjogren’s syndrome. Arthritis
Rheum 1988;31(8):1014-21
''TREATMENT AND MANAGEMENT

Reviews/Comprehensive Articles

Bajart AM. Common eye problems in the older
woman. Women Health 1985 Summer-Fall;10(2-3):
85-93

Ben-Aryeh H ; Miron D ; Berdicevsky I ; Szargel R ;
Gutman D. Xerostomia in the elderly: prevalence,
diagnosis, complications and treatment.
Gerodontology 1985 Winter;4(2):77-82

Fox PC. Systemic therapy of salivary gland
hypofunction. J Dent Res 1987 Feb;66 Spec No:689-
92

Manthorpe R ; Prause JU. Treatment of Sjogren’s
syndrome: an overview. Scand J Rheumatol [Suppl]
1986;61:237-41

Talal N. Overview of Sjogren’s syndrome. J Dent Res
1987 Feb;66 Spec No:672-4

Others

Asbell PA. The dry-eye patient and contact lenses.
J Ocul Ther Surg 1985;4(1):14-6

Billings RJ ; Meyerowitz C ; Featherstone JDB ;
Espeland MA ; Fu J ; Cooper LF ; Proskin HM.
Retention of topical fluoride in the mouths of
xerostomic subjects. Caries Res 1988;22(5):306-10

Bone RC ; Fox RI ; Howell FV ; Fantozzi R. Sjogren’s
syndrome: a persistent clinical problem.
Laryngoscope 1985 Mar;95(3):295-9

Burstein NL. The effects of topical drugs and
preservatives on the tears and corneal epithelium in
dry eye. Trans Ophthalmol Soc UK 1985;104( Pt 4):
402-9

Dalavanga YA ; Detrick B ; Hooks JJ ; Drosos AA ;
Moutsopoulos HM. Effect of cyclosporin A (CyA)

on the immunopathological lesion of the labial
minor salivary glands from patients with Sjogren’s
syndrome. Ann Rheum Dis 1987 Feb;46(2):89-92

Drosos AA ; Skopouli FN ; Costopoulos JS ;
Papadimitriou CS ; Moutsopoulos HM. Cyclosporin
A (CYA) in primary Sjogren’s syndrome: a double
blind study. Ann Rheum Dis 1986 Sep;45(9):732-5

Drosos AA ; van Vliet-Dascalopoulou E ;
Andonopoulos AP ; Galanopoulou V ; Skopouli 9
FN ; Moutsopoulos HM. Nandrolone decanoate
(deca-durabolin) in primary Sjogren’s syndrome: a
double blind pilot study. Clin Exp Rheumatol 1988
Jan-Mar;6(1):53-7

Duxbury AJ ; Hayes NF ; Thakkar NS ; et al. Clinical
trial of a mucin-containing artificial saliva. IRCS
Med Sci 1985;13(12):1197-8

el-Mallakh RS ; Bryan RK ; Masi AT ; Kelly CE;
Rakowski KJ. Long-term low-dose glucocorticoid
therapy associated with remission of overt renal
tubular acidosis in Sjogren’s syndrome. Am J Med
1985 Oct;79(4):509-14

Epstein JB ; Schubert MM. Synergistic effect of
sialagogues in management of xerostomia after
radiation therapy. Oral Surg Oral Med Oral Pathol
1987 Aug;64(2):179-82

Fox PC ; van der Ven PF ; Baum BJ ; Mandel ID.
Pilocarpine for the treatment of xerostomia
associated with salivary gland dysfunction. Oral Surg
Oral Med Oral Pathol 1986 Mar;61(3):243-8

Friberg B ; Jonsson R ; Linde A. Salivary kallikrein in
Sjogren’s syndrome. Clin Exp Rheumatol 1988;6(2):
135-8

Gilbard JP ; Kenyon KR. Tear diluents in the
treatment of keratoconjunctivitis sicca.
Ophthalmology 1985 May;92(5):646-50

Golubovi:c S ; Parunovi:c A. Corneal perforation in
dry eye patients. Fortschr Ophthalmol 1987;84(1):
33-7
''Greenspan D ; Daniels TE. Effectiveness of
pilocarpine in postradiation xerostomia. Cancer
1987 Mar 15;59(6):1123-5

Kawashima K. Effect of bromhexine on Sjogren’s
syndrome accompanied by rheumatoid arthritis.
Nippon Ika Daigaku Zasshi 1988 Apr;55(2):191-200

Kono I ; Matsumoto Y ; Kono K ; Ishibashi Y ;
Narushima K ; Kabashima T ; Yamane K ; Sakurai
T ; Kashiwagi H. Beneficial effect of topical
fibronectin in patients with keratoconjunctivitis sicca
of Sjogren’s syndrome. J Rheumatol 1985 Jun;12(3):
487-9

Kralian LM. What’s artificial in artificial tears? Am J
Optom Physiol Opt 1986 Apr;63(4):304-8

Laflamme MY ; Swieca R. A comparative study of two
preservative-free tear substitutes in the management
of severe dry eye. Can J Ophthalmol 1988 Jun;23(4):
174-6

LaMotte J ; Grossman E ; Hersch J. The efficacy of
cellulosic ophthalmic inserts for treatment of dry
eye. J Am Optom Assoc 1985 Apr;56(4):298-302

Lemp MA. General measures in management of the
dry eye. Int Ophthalmol Clin 1987 Spring;27(1):36-
43

Lemp MA. New modalities in treatment of ocular
surface disease. Trans New Orleans Acad
Ophthalmol 1987:297-306

Lemp MA. Recent developments in dry eye
management. Ophthalmology 1987 Oct;94(10):1299-
304

Lemp MA. Tear film: new concepts and implications
for the management of the dry eye. Trans New
Orleans Acad Ophthalmol 1987:53-64

Limberg MB ; McCaa C ; Kissling GE ; Kaufman HE.
Topical application of hyaluronic acid and
chondroitin sulfate in the treatment of dry eyes. Am
J Ophthalmol 1987 Feb 15;103(2):194-7

10

Lindahl G ; Calissendorff B ; Carle B. Clinical trial of
sustained-release artificial tears in
keratoconjunctivitis sicca and Sjogren’s syndrome.
Acta Ophthalmol (Copenh) 1988 Feb;66(1):9-14

Malmstrom MJ ; Segerberg-Konttinen M ; Tuominen
TS ; Hietanen JH ; Wolf JE ; Sane JI ; Konttinen
YT. Xerostomia due to Sjogren’s syndrome.
Diagnostic criteria, treatment and outlines for a
continuous dental care programme and an open
trial with Sulfarlem. Scand J Rheumatol 1988;17(2):
77-86

Marner K ; Prause JU. A comparative clinical study of
tear substitutes in normal subjects and in patients
with keratoconjunctivitis sicca. Acta Ophthalmol
(Copenh) 1984 Feb;62(1):91-5

Mengher LS ; Pandher KS ; Bron AJ ; Davey CC.
Effect of sodium hyaluronate (0.1%) on break-up
time (NIBUT) in patients with dry eyes. Br J
Ophthalmol 1986 Jun;70(6):442-7

Nelson JD. Corneal abrasion resulting from a unit
dose artificial tear dispenser. Am J Ophthalmol
1987 Mar 15;103(3 Pt 1):333-4

Nelson JD ; Farris RL. Sodium hyaluronate and
polyvinyl alcohol artificial tear preparations. A
comparison in patients with keratoconjunctivitis
sicca. Arch Ophthalmol 1988 Apr;106(4):484-7

Norn M. The effects of drugs on tear flow. Trans
Ophthalmol Soc UK 1985;104( Pt 4):410-4

Oxholm P ; Manthorpe R ; Prause JU ; Horrobin D.
Patients with primary Sjogren’s syndrome treated
for two months with evening primrose oil. Scand J
Rheumatol 1986;15(2):103-8

Poland JM ; Dugan M ; Parashos P ; Irick N ; Dugan
W ; Tracey M. Comparing Moi-Stir to lemon-
glycerin swabs. Am J Nurs 1987 Apr;87(4):422, 424

Prause JU. Treatment of keratoconjunctivitis sicca
with Lacrisert. Scand J Rheumatol [Suppl] 1986;
61:261-3
''Prause JU ; Jensen OA ; Manthorpe R. Effect of
bromhexine, ambroxol, and placebo on clinical and
histopathological changes in "Sjogren" mice.
Graefes Arch Clin Exp Ophthalmol 1985;223(5):
259-64

Prause JU ; Krogsaa B ; Lose B. Treatment of
keratoconjunctivitis sicca with Elmiron. Scand J
Rheumatol [Suppl] 1986;61:259-60

Rhodus NL. Detection and management of the dental
patient with Sjogren’s syndrome. Compendium 1987
Sep;8(8):578, 580, 582 passim

Sanchez Palacios A ; Quintero A ; Clavero Garin A ;
Verrier Hernandez A ; Esposo Ferrero A ; Sanchez
Ruiz A ; Iglesias D ; Aparicio Duque R.
Immunoregulation with methisoprinol in Sjogren’s
syndrome. Allergol Immunopathol (Madr) 1986
Jan-Feb;14(1):21-9

Schiodt M ; Oxholm P ; Jacobsen A. Treatment of
xerostomia in patients with primary Sjogren’s
syndrome with sulfarlem. Scand J Rheumatol
[Suppl] 1986;61:250-2

Smith DL ; Lucas LM. Sjogren’s syndrome. More than
dry eyes and dry mouth. Postgrad Med 1987 Jul;
82(1):123-31

Sreebny LM ; Valdini A. Xerostomia. A neglected
symptom. Arch Intern Med 1987 Jul;147(7):1333-7

Stuart JC ; Linn JG. Dilute sodium hyaluronate
(Healon) in the treatment of ocular surface
disorders. Ann Ophthalmol 1985;17(3):190-2

Tarail J. Sjogren’s syndrome. A dry-eyed diary. Am J
Nurs 1987 Mar;87(3):324-6

Teutsch E ; Hill M. Sjogren’s syndrome. Adding
moisture to your life. Am J Nurs 1987 Mar;87(3):
326-9

Treatment of xerostomia. Med Lett Drugs Ther 1988
Jul 29;30(771):74-6

11

Tseng SC. Topical tretinoin treatment for dry-eye
disorders. Int Ophthalmol Clin 1987 Spring;27(1):
47-53

Tseng SC. Topical tretinoin treatment for severe dry-
eye disorders. J Am Acad Dermatol 1986 Oct;15
(4 Pt 2):860-6

Tseng SC ; Maumenee AE ; Stark WJ ; Maumenee
TH ; Jensen AD ; Green WR ; Kenyon KR. Topical
retinoid treatment for various dry-eye disorders.
Ophthalmology 1985 Jun;92(6):717-27

Ubels JL ; Edelhauser HF ; Foley KM ; Liao JC;
Gressel P. The efficacy of retinoic acid ointment for
treatment of xerophthalmia and corneal epithelial
wounds. Curr Eye Res 1985 Oct;4(10):1049-57

Verheul HA ; Schot LP ; Schuurs HW. Therapeutic
effects of nandrolone decanoate, tibolone,
lynestrenol and ethylestrenol on Sjogren’s
syndrome-like disorder in NZB/W mice. Clin Exp
Immunol 1986 May;64(2):243-8

Visch LL ; ’s-Gravenmade EJ ; Schaub RM ; Van
Putten WL ; Vissink A. A double-blind crossover
trial of CMC- and mucin-containing saliva
substitutes. Int J Oral Maxillofac Surg 1986 Aug;
15(4):395-400

Vissink A ; Huisman MC ; ’s-Gravenmade EJ.
Construction of an artificial saliva reservoir in an
existing maxillary denture. J Prosthet Dent 1986 Jul;
56(1):70-4

Vissink A ; Panders AK ; ’s-Gravenmade EJ ; Vermey
A. Treatment of oral symptoms in Sjogren’s
syndrome. Scand J Rheumatol [Suppl] 1986;61:
270-3

Volker-Dieben HJ ; Kok-van Alphen CC ; Hollander
J ; Kruit PJ ; Batenburg K.. The palliative treatment
of the dry eye. Doc Ophthalmol 1987 Sep-Oct;67
(1-2):221-7

Vrielinck LJG ; Van Parys G ; Van Damme B;
Bossuyt M. Sicca syndrome with iron deposition in
the salivary glands. Int J Oral Maxillofac Surg 1988;
17(1):11-3
''Walters MT ; Rubin CE ; Keightley SJ ; Ward CD ;
Cawley MI. A double-blind, cross-over, study of
oral N-acetylcysteine in Sjogren’s syndrome. Scand J
Rheumatol [Suppl] 1986;61:253-8

Watkinson S. Dry eye syndrome. Nurs Times 1985
Oct 23-29;80(43):32-5

Weiss WW Jr ; Brenman HS ; Katz P ; Bennett JA.
Use of an electronic stimulator for the treatment of
dry mouth. J Oral Maxillofac Surg 1986 Nov;44(11):
845-50

Willis RM ; Folberg R ; Krachmer JH ; Holland EJ.
The treatment of aqueous-deficient dry eye with
removable punctal plugs. A clinical and impression-
cytologic study. Ophthalmology 1987 May;94(5):
514-8

Wright P ; Cooper M ; Gilvarry AM. Effect of
osmolarity of artificial tear drops on relief of dry eye
symptoms: BJ6 and beyond. Br J Ophthalmol 1987
Feb;71(2):161-4

Wright WE. Management of oral sequelae. J Dent Res
1987 Feb;66 Spec No:699-702

12
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