UNIVERSITY OF ILLINOIS : | |i-| | ; i 
 
 SOME CONDITIONS 
 
 ADVANCED LIFE 
 
 IN WHICH 
 
 THE SYRUP OF HYPOPHOSPHITES 
 
 (FELLOWS - ) • 
 
 / '' 
 
 ' ; 
 
 IS BENEFICIAL. 
 
 [res THE MEDICAL PROFESSION 
 
 PART V. 
 
 NEW YOEK: 48, VESEY S/TREET 
 PARIS : 5, RUE DE LA/ PAIX. 
 
 LONDON: I 
 
 JAS. I. FELLOWS, 67, HOLBORIN VIADUCT 
 
 1885 i 
 
To the Medical Gentlemen who have honoured me 
 with the Reports and Testimonials which so greatly 
 enhance the value of my publications , and to whom 
 the wo. ks are respectfully ' dedicated , I tender the 
 most cordial thanks , with the assurance that the 
 contributions shall be used in such manner only, 
 as is consistent with the ethics of the Profession. 
 
 JAMES I. FELLOWS. 
 
 London, July , 1885. 
 
& 1 S. 54 
 P 2>3s 
 
 I 
 
 PREFACE. 
 
 i 
 
 j 
 
 C3r 
 
 
 rO 
 
 
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 -A 
 
 fO 
 
 Mr. Fellows avails himself once more of 
 the opportunity of thanking the Profession 
 for their liberal recognition of the value of 
 his Syrup of the Hypophosphites. 
 
 He feels it desirable again to point out the 
 fraudulent practices of some dispensing che¬ 
 mists, who substitute fictitious articles for 
 the Syrup, When prescribed. The conse¬ 
 quences are :— 
 
 1. —The medical man is disappointed, in 
 not getting the desired results,—Why ? 
 because the Strychnia is precipitated, and so 
 the patient does not get the expected benefit. 
 
 2. —The precipitated Strychnia is taken 
 altogether in the last dose, which may thus 
 be positively poisonous. ; 
 
 Many of such imitative preparations 
 been examined by Mr. Fellows, but not^ 
 
 994713 I 
 
IV 
 
 PREFACE. 
 
 lias been found to possess the distinctive 
 characters, of his Syrup, viz :—freedom from 
 acid reaction, stability in vacuo, or, indeed, 
 the same composition, those blended elements 
 which render it so potent a remedy in disease. 
 
 He ventures to think that in their own 
 interests, as well as in the interests of their 
 patients, it is well for the Medical Profession 
 to employ an agent of known composition 
 and properties, which is further guaranteed by 
 distinguishing marks, in order to avoid dis¬ 
 appointment ; while as to the patient, the 
 importance of having the genuine article is 
 obvious. 
 
 He hopes to retain both the confidence of 
 the medical man and the patient, by main¬ 
 taining the composition of his Syrup 
 unimpaired. He should further like to point 
 out how well adapted this Syrup is for use by 
 itself, as an habitual tonic, or where a tonic is 
 Squired for some considerable time. 
 
 X Letters CLXI CLXXVIII., CLXXIX., CCVIII.) 
 
SOME CONDITIONS 
 
 OF 
 
 , I 
 
 ADVANCED LIFE 
 
 IN WHICH 
 
 FELLOWS’ SYRUP OF THE HYPOPHOSPHITES 
 
 IS BENEFICIAL. 
 
 The success of his fourth pamphlet on the utility 
 of this Syrup in the maladies incident to childhood, 
 encourages Mr. Fellows to essay a fifth. In it the 
 maladies of advanced life will be considered ; especially 
 as to. their therapeutic aspect, and the advantage of 
 giving his Syrup of the Hypophospliites in many in¬ 
 stances—for the relief of which it seems to possess 
 special properties in gooct combination. 
 
 The onCome of age has a benumbing effect upon the 
 whole organism, not only the motor and intellectual pro- 
 cessses, but also the activity of the viscera and the energy 
 of the organic life. It has, indeed, widespread effects, 
 
 / 
 
, ■ - - - 
 
 f, SOME CONDITIONS OF ADVANCED LIFE. 
 
 wbicli have thus been summarised : “Not only is the 
 locomotion affected and the features altered, but the 
 working of every part of the organism becomes modified 
 and less efficient. The eye becomes gradually worn out, 
 especially at the distances most commonly used, necessi¬ 
 tating the aid of glasses or lenses ; and the skilful limber 
 hand grows stiff and loses its cunning. The ear no longer 
 possesses its acuteness of hearing, and receives but im¬ 
 perfectly the air vibrations which it converts into sound. 
 The internal organs perform their functions but slug¬ 
 gishly, and often inefficiently ; the breathing becomes 
 laborious, and the heart is less equal to the demands 
 upon it; the bowels are less active, and the stomach 
 enfeebled; the kidneys no longer preserve their integrity, 
 and great variations become manifest in their secretion; 
 the skin is no longer soft, pliable, and capable of free 
 secreting action, but is dry, wrinkled, and inactive. The 
 nervous system loses its grasp, and the once enterprising 
 brain becomes essentially conservative and indisposed to 
 change; the once tenacious memory becomes treacherous 
 and untrustworthy; and the reasoning powers, once clear 
 and judicial, become enfeebled, and petulance and obsti¬ 
 nacy obtain where breadth of thought and tolerance were 
 once supreme.” (The Maintenance of Health). Such, 
 then, is a brief summary of what is given at greater 
 length and in the fulness of detail by Dr. Maclachlan in 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES . 7 
 
 his ‘ ‘ Treatise on tlie Diseases and Infirmities of Advanced 
 Life.” Dr. Maclaclilan was the physician to the Chelsea 
 Hospital, and thus enjoyed special opportunities for ob¬ 
 serving the maladies on which he wrote. He says : 
 “ Failing strength and activity, weakening of the nutri¬ 
 tive, organic, and reproductive functions, and shortness 
 of breath on moderate exertion, are among the earliest 
 indications of physical decline-even in the most healthy.” 
 It is this growing enfeeblement of the frame in each of 
 its parts which is the great fact to be borne in mind in 
 dealing with the maladies of advanced life. There is no 
 longer the tendency to the acute inflammatory morbid 
 activities which obtains in earlier years. Disease 
 assumes an asthenic type, and tends to spread from 
 tissue-atony. Inflammation of the lungs, for instance, 
 no longer requires lowering measures but active tonic 
 treatment. Mucous membranes are prone to rheums, 
 or in other words, instead of full-grown complete epithe¬ 
 lium being formed over their surfaces imperfect mucous 
 corpuscles, with a considerable amount of fluid are thrown 
 off: telling of impairment of formative power. The 
 muscles lose their plumpness and waste; the articulations 
 stiffen; and locomotion is limited, by which visceral 
 congestion is favoured. The machine, indeed, wears out 
 generally; some part giving way more than others in 
 many instances, but still there is impairment through- 
 
8 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 out the body structure: which must never be for¬ 
 gotten. 
 
 Diseases of the Assimilative Organs. —The as¬ 
 similative organs suffer in the general decay and lose 
 functional activity while presenting anatomical evidences 
 of their decadence. “ Participating in the general wasting 
 of the organs and tissues, the stomach and intestines 
 lose bulk and become thinner in old age. The glandular 
 apparatus is atrophied. Many glands seem to have 
 entirely disappeared.” The secretory tubules of the 
 stomach share in the general impairment, alike with 
 the absorbent glands of the intestine. Thence follow 
 imperfect digestion of the food, and lessened absorption 
 from the soluble contents of the alimentary canal. In 
 consequence thereof the food of the aged has to be 
 specially digestible as well as nutritive, so as to give the 
 maximum of digested products with the smallest tax on 
 the assimilative processes. To maintain the efficiency 
 of the digestive system a tonic combining strychnia 
 with phosphorus seems specially indicated. 
 
 The first is a tonic to the muscular walls of the 
 stomach, which become more or less inert ; while 
 phosphorus, in the form of the readily assimilable hypo- 
 phosphites, feeds the'nervous centres of the viscera. 
 The syrup thus gives tone to the waning energies of the 
 digestive canal. 
 
FELLOWS' SYRUP OF THE HYPOPIIOSPHITES. 9 
 
 And here a few words may be said as to the special 
 utility of the syrup in conditions of enfeebled assimila¬ 
 tion. The value of wine as a stimulant, in addition to 
 good food in the enfeebled digestion of the aged, has 
 ever been recognised from the earliest time. Ulysses 
 urges upon his aged father a regimen well suited to his 
 waning energies. 
 
 “ Warm baths, good food, soft sleep and generous wine, 
 These are the rights of age and should be thine,” 
 
 And Jutus von Liebig pronounced wine to be “ as 
 milk for the aged.” The stimulant effect of generous 
 wine in the debilitated assimilation of elderly persons has 
 been largely valued in the past. At the present time 
 the growing objection to alcoholic stimulants and the 
 spread of the temperance, or even the total abstinence 
 movement, has limited the resort to wine, and this in 
 turn has led to the selection of substitutes of non¬ 
 alcoholic character. For those who decline to accept the 
 aid of wine, as did Timothy, who had to be told to 
 “ Drink no longer water but a little wine for thy 
 stomach’s sake and thine often infirmities” and who 
 need something of a stimulant character in' order to 
 rouse the flagging powers of digestion, this syrup offers 
 special advantages ; and one or two teaspoonfuls in a 
 tumbler of water, form a bitter tonic, sharpening the 
 
10 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 appetite, and giving tone to the digestive organs, taken 
 before or with meals. 
 
 Then the intestines share in the waxing sluggishness 
 
 — the numbness which is pervading the whole system,— 
 
 and the bowels are apt to become chronically loaded in 
 
 age. For the relief of such a state the syrup is admirably 
 
 / 
 
 adapted, the strychnine exercising its well-known effect 
 of increasing the tone of the muscular fibre of the in¬ 
 testine. To so give tone to the bowels is preferable to 
 the too common resort to purgatives, which open the 
 bowels for the time and then leave them to become 
 loaded again. Piles and other rectal and anal troubles 
 are the common outcome of habitually loaded bowels in 
 advanced life. A laxative dose of medicine, now and 
 then, however, is not objectionable ; and is to be pre¬ 
 ferred to straining at stool, which is fraught with 
 danger when the arteries are growing brittle—as they 
 are apt to become in advancing years. 
 
 Diseases of the liver are also more prevalent as life 
 reaches its termination; not acute diseases, but those 
 of a more chronic character especially atonic congestion. 
 The torpor of the portal system is furthered by the in¬ 
 creasing inability to take exercise, and thus, as Cullen 
 pointed out, the liver is rendered liable to congestions 
 which “generally escape detection, or are only suspected 
 in the living.” So far as possible then, tonics, with 
 
 I 
 
FELLOWS' SYRUP OF THE HYPO PHOSPHITES. 11 
 
 attention to the dietary and the state of the bowels, 
 should be used to, prevent such congestions of the liver; 
 and by stimulating that important vise us, as well as by 
 increasing the general vigour, to ward off structural 
 change in it. 
 
 The ordinary symptoms of disorder in the abdominal 
 viscera are either dyspeptic and belonging to the stomach, 
 with distension after eating, and less frequently pain; or 
 there is the persisting sense of fullness of loaded bowels; 
 or weight and pain over the liver when that viscus is 
 affected. When these symptoms are manifested, either 
 few or many, then a general tonic is indicated, of which 
 this syrup is the best for practical purposes. 
 
 Diseases of the Circulatory Organs. —That age 
 makes itself felt upon the different portions of the cir¬ 
 culatory apparatus is a matter which has long been 
 known to pathologists in the post-mortem room, as well 
 as to practising physicians. 
 
 As life advances the arteries become hard, as Hunter 
 pointed out, and this atheroma (as this condition is 
 termed) in time undergoes either a calcareous degenera¬ 
 tion (by the infiltration of lime salts into the altered 
 coats), or a fatty degeneration by which the hardened 
 portions are softened and so all the more readily torn. 
 In arterial degeneration there is a great tendency for 
 the wall to yield at certain points and thus to the forma- 
 
12 SOME CONDITIONS OF ADVANCED LIFE. 
 
 tion of an aneurism, or the weakened coat may be torn 
 through, and thus the patient bleeds to death inwardly. 
 Or effort (raising the internal pressure) at one time may 
 develop an aneurism, the sac of which a future effort 
 may rupture. All these consequences are the sequel® of 
 ' that hardening of the arteries spoken of as atheroma; 
 and therefore the avoidance of this initial condition is a 
 matter of primary importance. If it can be staved off 
 its sequel® are avoided. By a regulated dietary and the 
 avoidance of excess of animal food, this morbid change 
 may be kept off; but as the loss of the stimulant animal 
 food is often keenly felt, it is well to add the syrup to 
 the new dietary, by which all sense of depression or 
 “feeling too low” can be avoided without entailing 
 undesirable results. A more material mattter still is the 
 change which takes place in the heart itself as age pro¬ 
 gresses—as time wears on with sure, if leaden foot. 
 Recent observations have told us that there is a certain 
 increase in hulk in the muscular wall of the heart as 
 maturity moves on to age, which is found along with the 
 above-mentioned hardening of the arteries. The hardened 
 arteries are not so readily distended by the cardiac systole 
 as of yore, and to overcome this resistance to the onward 
 flow of the blood on the ventricular contraction, a com- 
 XDensatory hypertrophy is set up. By this growth a new 
 balance is established which goes on for some time, the 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 15 
 
 individual still feeling well and vigorous. But as the 
 aorta becomes less and less elastic its rqcoil is impaired, 
 and this recoil of the elastic aorta is the force which 
 drives the blood into the smaller arteries—indeed is 
 the cause of the pulse, though not the direct cause. 
 The elastic. arterial system is always (in health) more 
 or less full of blood. When the heart contracts—the 
 ventricular systole—so much more blood is thrown into 
 the elastic arterial system. In this respect the circu¬ 
 latory system resembles the spray-apparatus. The heart 
 corresponds to the pump held in the hand, which con¬ 
 tracts rhythmically; the elastic arteries are the india- 
 rubber globe, or elastic reservoir (always more or less 
 full) which, always distended, converts the rhythmic flow 
 into the steady current of the out-going pipe. When 
 the elastic wall in either case loses its elasticity its 
 function is impaired. Consequently the flow of blood 
 into the coronary arteries on the aortic rebound is 
 impaired by the lessened elasticity in the arterial wall, 
 while the hardening process is often markedly developed 
 in these nutrient vessels of the heart. , Further, this 
 atheromatous change thickens the inner coat of the 
 affected arteries; including those of the coronary arteries, 
 and so lessens their lumen, or calibre, or bore. The 
 result of these two combined actions is the reduction 
 of the blood-current passing through the heart-walls, 
 
 I 
 
14 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 which leads in turn to their imperfect nutrition. Im¬ 
 paired nutrition cuts down the energies of the heart 
 and then failure of its action follows : at first partial 
 failure, finally cessation of action in diastole. When 
 the heart’s energy is lowered then a general tonic is 
 good, and the strychnia of the syrup especially indicates 
 its use in such conditions; all the more from the presence 
 of the other constituents, which constitute the combina¬ 
 tion one peculiarly adapted to such senile changes, 
 
 But partial failure of the heart’s action is not by any 
 means always the result of the grave morbid change 
 here described,—in other words, “fatty degeneration”; 
 nor indeed, when it is, does there attach to the early 
 stages of the necrobiotic change the grave prognostic 
 aspect which belongs to temporary failure in the later 
 and more advanced stages. In the early stages the line of 
 treatment, medicinal and dietetic, is that of an adynamic 
 condition, viz., suitable food and agents which, acting 
 through the nervous mechanism of the heart, will in¬ 
 crease the energy of the ventricular contractions. Very 
 commonly, however, heart failure is the result of mal¬ 
 nutrition of the heart not dependent upon arterial de¬ 
 generation, but due to other causes. When the general 
 nutrition is impaired, the heart, in unceasing action, is 
 insufficiently nourished : and, as a consequence, falters 
 in its work. Here improvement of the assimilation, and 
 
FELLOWS' SYRUP OF THE LIYPOPHOSPHITES. 15 
 
 better general nutrition lead to a fuller supply of pabulum 
 to the heart-walls, with the result of more energetic 
 action in them. The symptoms of a “badly-fed” heart 
 are identical with those of a “fatty” heart in its early 
 stages ; and their treatment also is identical. In both 
 cases improvement can be set up by appropriate measures; 
 though, of course, when the heart is the seat of fatty 
 degeneration the improvement is not, and cannot be, in 
 
 i / 
 
 the nature of things, permanent. Failure of the heart’s 
 action in persons advanced in years is not always the 
 result of the arterial degeneration described above (which 
 is a brief abstract of what is stated in Dr. Milner Fother- 
 gill’s Treatise “ The Heart and its Diseases ”); but is 
 more commonly due to a condition which can be relieved 
 by remedial agents, viz., impaired general nutrition. It 
 is by no means unusual for this remediable condition of 
 heart-failure to be mistaken for the graver condition 
 of fatty degeneration ; a mistake which too frequently 
 entails an attitude of hopelessness, which in turn inter¬ 
 feres with the adoption of remedial measures. 
 
 Yet remedial measures, wisely selected, will, in some 
 cases of heart failure, do permanent good ; while in the 
 early stages of fatty degeneration they will do temporary 
 good; and even when an advanced condition of mural 
 decay is obviously established they are not entirely 
 devoid of a temporary value. 
 
16 SOME CONDITIONS OF ADVANCED LIFE. 
 
 In cases of neurosal disturbance of tlie heart’s action, 
 as irregularity, or intermittency, or lowered energy— 
 otherwise partial syncope,—all conditions commonly 
 seen in persons advanced in years, a tonic compounded 
 of various agents like the syrup of the hypophosphites 
 is clearly indicated. Indeed, in all cases of perverted 
 action of the heart, the syrup is well worth a trial. 
 Curable cases will yield to it; cases where structural 
 decay may be suspected will often be found to improve 
 under its use, especially if the fatty degeneration be 
 neither widespread nor far advanced. 
 
 There are, liow T ever, other cardiac conditions than 
 those just described where the syrup can be taken with 
 advantage. More extended observation has done much 
 to correct the impression that disease of the valves of 
 the heart is always a morbid process advancing com¬ 
 paratively rapidly from bad to w r orse. Many persons 
 with a certain amount of injury to their cardiac valves 
 attain to a very advanced age. The injury is done, 
 and the mutilated valve remains as unchanging as a 
 scar; there is no tendency to further valve-change. 
 Here the individual is crippled to a certain extent, and 
 a comparatively quiet life is necessary to length of 
 days ; but that is all. Of course, where such an injury 
 exists, any failure or impairment of the general health 
 is apt to make it felt ; and any' mal-nutrition of the 
 
FELLOWS' SYRUP OF THE IIYPOPHOSPHITES. 17 
 
 heart-wall reveals the hidden hurt. Under these 
 circumstances a suitable remedial agent is of great 
 service ; not, however, in any way undoing the valve- 
 mutilation, but in restoring tone to the failing mus¬ 
 cular walls. At other times and in other cases 
 there is a condition of dilatation existing in the cardiac 
 chamber—sometimes in the left ventricle, at other 
 times only in the right—limiting the patient’s powers 
 for locomotion or other exertion, commonly spoken 
 of as a “ weak heart.” Such a permanent condition is 
 very liable to be felt pronouncedly when the general 
 health is impaired, as by intercurrent indigestion, 
 diarrhoea, or other exhausting malady. But in these 
 temporary conditions of heart-failure much can be done 
 to restore the vigour of the heart by suitable food and 
 appropriate remedial agents. Of course, rest—limiting 
 the demand upon the heart—is essential to the recovery 
 of its tone ; and by all these various measures combined 
 a very great deal can be done for cases too commonly 
 regarded with a feeling of despair. 
 
 Diseases of the Respiratory Organs.— Even still 
 more constant are the changes wrought in the respiratory 
 organs by age. The cartilages of the ribs become ossified; 
 a matter which limits the mobility of the thorax; the 
 trachial rings from like change become rigid, while 
 the lungs themselves waste in advanced life, and the 
 
 B 
 
18 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 bronchial tubes become the seat of the rheum. From 
 these circumstances combined, the breath is short, and 
 any exertion entails serious respiratory efforts. The 
 thoracic case, or box, becomes immovable, and is lifted 
 up bodily by the respiratory muscles of the neck, while 
 the diaphragm descends at each inspiratory effort. Con¬ 
 sequently flatulent distension of the abdomen—pressing 
 on the heart and also opposing the descent of the dia- 
 
 I 
 
 pliragm—produces much distress in the breath in these 
 cases of thoracic trouble. There are, indeed, many morbid 
 forces at work to embarrass the respiration in elderly 
 persons. Rokitanski, the great pathologist, writes 
 
 “ The impaired state of the respiratory muscles renders 
 the act of inspiration difficult and imperfect; the deficient 
 contractility of the pulmonary tissues, together with 
 the above-named muscular weakness, opposes similar 
 obstacles to the act of inspiration, while' the surface of 
 the lungs present to the atmospheric air so obliterated 
 a capillary net-work, that only a small quantity of 
 blood can be submitted to the vivifying process of arte- 
 rialisation.” No wonder then the breath is short in a,ge ! 
 
 What remedial agent will most efficiently relieve the 
 patient suffering from such respiratory embarrassment ? 
 One which will act directly upon the respiratory centre 
 in the medulla by which the inspiratory act is brought 
 about, is the answer which physiological teaching prompts. 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 19 
 
 Tlie respiratory centre is located in the medulla, and what 
 says one of the best as well as mpst recent authorities 
 on Materia Medica and Therapeutics ? “ The medulla 
 
 is stimulated by strychnia in all its important centres. 
 The respiratory centre is increased in activity, and 
 transmits powerful impulses downwards to the already 
 excited cord, thus causing increased frequency and depth 
 of the movements of the chest.”— (Dr. Mitchell Bruce.) 
 An agent which will thus stimulate the respiratory centre 
 and enable it to send out powerful efferent currents, 
 throwing not only the ordinary but also the accessory 
 muscles of respiration into energetic action, relieves the 
 patient, who is suffering under respiratory embarrass¬ 
 ment, even from direct voluntary effort. By its means 
 the breathing becomes once more automatic, and fairly 
 independent of voluntary effort. Relieved from the 
 necessity for voluntary effort to keep up the respiration, 
 the patient can sleep without the need for an opiate. 
 Such, then, is what modern therapeutic investigation 
 tells us as to the treatment of dyspnoea. Rested by 
 sleep, able to breathe without the necessity for conscious 
 effort, the patient can once more get about without dis¬ 
 comfort, and with obvious good effect upon his general 
 health. Improved breathing carries with it more perfect 
 oxygenation of the blood, and the waste matters with 
 which the blood is commonly laden in age are thus got rid 
 
 b 2 
 
20 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 of; being burnt up and consumed. Wliat is needed in all 
 respiratory embarrassment is more perfect respiratory 
 movements, and tliese can be excited by the strychnia, 
 which forms a marked constituent of this syrup : the 
 other factors contributing to the good effects. 
 
 This is a very important therapeutic matter, as Dr. 
 Maclaclilan writes ;—“ The diseases of the respiratory 
 organs are at all periods of life the most common to 
 which man is liable. As age advances, some of these 
 increase in frequence and fatality, while others progres¬ 
 sively disappear. Among the former, bronchitis and its 
 common associate, asthma, are peculiarly prevalent. 
 These two diseases carry off immense numbers of old 
 people, and certain varieties of them almost exclusively 
 appertain to old age.” 
 
 All demands upon the respiration are badly borne by 
 elderly people, and even slight bronchial attacks in those 
 whose respiratory organs are already seriously impaired, 
 are fraught with an element of danger. A teaspoonful 
 of the syrup every three or four hours will successfully 
 tide many aged persons over a bronchial seizure to 
 which, without it, they would probably succumb. With 
 the lungs already the seat of senile marasmus, and the 
 other concomitant morbid conditions alluded to above, a 
 slight addition to the respiratory difficulty becomes a 
 grave matter in age. 
 
FELLOWS' SYRUP OF THE IIYPOPHOSPHITES. 21 
 
 In all cases of respiratory embarrassment, whether 
 
 due to pulmonic congestion taking its origin in a lesion 
 
 in the mitral valve, or to permanent lung or bronchial 
 
 trouble, by which the right side of the heart is distended 
 
 and embarrassed, an agent which will so improve the 
 
 / 
 
 breathing as to render it once more automatic and inde¬ 
 pendent of voluntary effort to maintain the respiration is 
 of incalculable value ; and such an agent is to be found 
 in the Syrup of Hypophosphites. Not only is there 
 present in it an agent acting directly upon the nerve 
 centres, which preside over the circulation and respir¬ 
 ation ; but it contains a considerable quantity of 
 phosphorus, in a form readily broken up by the digestive 
 act, and so furnishing free phosphorus for the nutrition 
 and repair of these over-taxed discharging nervous 
 centres. 
 
 Diseases of the Nervous System— “ Next to 
 diseases of the respiratory organs, the diseases of the 
 nervous centres constitute the largest number of admis¬ 
 sions of an important nature into hospitals allotted to 
 the old,” writes Dr. Maclaclilan. By this, of course, is 
 meant grave maladies threatening life. But outside and 
 beyond such serious diseases, there are a host of minor 
 troubles, and even some grave morbid changes for which 
 admission to hospitals is not usually sought; nor would 
 it be of much avail if accorded. “ Once a man and twice 
 
22 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 a child,” is a proverb which tells in the briefest speech of 
 the gradual evolution or “ unfolding ” of the brain which 
 goes on while the infant develops slowly into the man— 
 conscious of the fulness of his powers ; and also of tliat 
 involution or “infolding,” which follows upon maturity 
 in time ; and which, when well-pronounced, is spoken of 
 as “ dotage.” Some old persons retain their faculties to 
 the end. But this is the exception not the rule ! In the 
 bulk of cases mental impairment becomes manifest when 
 the allotted span is reached. There are seen petulance, 
 querulousness, garrulity, caprice, likes and dislikes, which 
 
 i 
 
 tell that the judgment is impaired, even when the in¬ 
 tellect still seems fairly good. The higher centres which 
 rule the rest are the last to come and the first to go. 
 Consequently the tendency is for the impulses once more 
 to escape from the control of the will, or, in other words, 
 the character becomes modified—and not for the better. 
 
 There are, too, physical changes of like character and 
 corresponding thereto. The ear becomes dull, the sight 
 fails, the lissom hand begins to lose its cunning; the 
 step is no longer springy, the carriage is less erect. 
 Locomotion is impaired ; the breath is comparatively 
 short; the heart is feeble, or its rhythm is affected ; the 
 bowels are sluggish; and the viscera lose tone; while 
 the bladder centres grow irritable. Indeed, the sympa¬ 
 thetic or organic nervous system, like the cerebro-spinal, 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 23 
 
 is feeling the effects of coming decay. Nor will we be 
 surprised at these results when we reflect upon what the 
 scalpel reveals. 
 
 “ The nervous centres waste, harden, and lose weight, 
 and the nerves participate in these changes,” writes 
 Dr. Maclaclilan pithily. The nerves participate in these 
 changes, and Lobstein has observed that the change is 
 marked in branches of the sympathetic nerve ; while 
 Engel found the ganglia to have shrunk, by wasting of 
 the ganglion-cells ; the development of pigment not com¬ 
 pensating (in bulk, let alone functional activity) for the 
 cell-decay. Such, then, are the anatomical substrata of 
 the alterations which may be observed while the person 
 is living. At the same time the blood-vessels, and 
 especially those of the brain proper, undergo their own 
 changes. Their arterial walls become inelastic, and are 
 either calcareous or fatty according to circumstances ; 
 in either case the blood-current flows less freely through 
 the brain, while the artery is liable to be easily 
 ruptured by any straining. Consequently, apoplexy is 
 more common as life wears on to its finish. 
 
 The diseases of the nervous system in age are due in 
 some instances to changes in the blood-vessels rather 
 than in the nerve-tissues themselves ; while in other 
 cases there is a growth of connective-tissue, or the 
 neuroglia, that curtails the true nerve-tissues, as in dis- 
 
/ 
 
 I 
 
 24 SOME CONDITIONS OF ADVANCED LIFE. 
 
 seminated sclerosis, otherwise but erroneously spoken 
 of as “ softening of the brain,” when general and wide¬ 
 spread ; or there is a local growth of such tissue as a 
 tumour. In wide-spread sclerosis there is premature loss 
 of muscular power and intellectual decay combined; while 
 in ordinary dotage there is merely a withering or wasting 
 of the brain; just as there is senile marasmus in the lungs. 
 
 Such, then, are the changes wrought in the nervous 
 system by the oncome of age. There is a physical 
 change going on which manifests itself in lowered func¬ 
 tion ; there are alike anatomical changes and physio¬ 
 logical modifications of function; all, however, in the 
 direction of loss—of diminished capacity and structural 
 degradation. There is, indeed, in the language of Hugh- 
 lings Jackson a general involution, a sort of obsolescence 
 creeping over the nervous system in all its parts. 
 
 To what therapeutic measures do these morbid states 
 point ? Clearly to a combination which contains at 
 once nervine tonics, as quinine and strychnine, with an 
 hasmatic, as iron, and a form of phosphorus which is 
 unstable and so readily broken up; and this last is found 
 in the liypophosphorous acid. When there is impaired 
 nervous energy, whether the morbid change is one of 
 wasting, or there is pressure upon the encephalic mass as 
 by an effusion of blood, forming a clot, the proper nutri¬ 
 tion of the nervous system is the cardinal matter to be 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHPTES. 25 
 
 ever kept in view. Not only is the cerebro-spinal nervous 
 system affected, but, as we have seen, the ganglia and 
 nerves of organic life are implicated in this structural 
 decay of age, and so the different viscera are enfeebled. 
 
 General Rules for the Aged.— The union of a 
 nerve-food (phosphorus) with nervine tonics (quinine 
 and strychnine) is what is to be desired for such a 
 widespread change; no matter whether some more 
 special or local morbid change he also present, or not. 
 By the use of easily assimilable food, attention to the 
 general health, including such exercise as is suitable, 
 and the steady use of this syrup, many elderly people 
 will and can prevent or retard the advance of senility. 
 And this it is which Cicero advocated in his work on Old 
 Age. “We must make a stand against old age, and its 
 faults must he atoned for by activity ; we must fight, as 
 it were, against disease, and in like manner against old 
 age. Regard must be paid to health; moderate exer¬ 
 cise must he adopted ; so much of meat and drink must 
 be taken, that the strength may be recruited, not op¬ 
 pressed. Nor, indeed, must the body alone be supported, 
 but the mind and the soul much more; for these also, 
 unless you drop oil on them as on a lamp, are extin¬ 
 guished by old age.” Shrewd, sensible remarks, these ! 
 We cannot arrest completely the oncome of age, but we 
 can retard its advances ; and certainly should not invite 
 
26 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 its advent. And wliat says Hufeland on tlie matter in 
 his work on “ The Art of Prolonging Life ?” “It needs 
 not be objected that great age is the unnatural state, or 
 an exception from the rule, and that a short life is 
 perhaps the natural condition. Almost all those kinds 
 of death which take place before the hundredth year 
 are brought on artificially—that is to say, by disease or 
 accident; and it is certain that by far the greater 
 number die an unnatural death.” 
 
 If then the aged could be protected against cold,—the 
 generation of body-lieat being impaired by age ; if they 
 could be fed on nutritive and easily digestible food ; if 
 they could be secured against accident : in other words, 
 if they could be placed under the ideally most favourable 
 circumstances, greater length of days is feasible in the 
 bulk of cases. Granting that all this can be managed, 
 there still remains—what can be done for them by 
 modern knowledge ? The nervous system decays and 
 needs its own pabulum. Phosphorus is essential to the 
 formation of lecithin—the phosphorized fat which is 
 the food of the nervous system par excellence—and this, 
 in a desirable form, is furnished by the syrup of the 
 hypophosphites; while, beyond the phosphorus it con¬ 
 tains nervine tonics and haematics. It is not claimed,—- 
 it is not essayed here to attempt to claim, for the syrup 
 supernatural powers; but merely to put forward dis- 
 
FELLOWS' SYRUP OF THE 1IYP0PH0SPHITES. 27 
 
 tinctly and clearly its claims to be regarded as a 
 combination peculiarly adapted to the requirements of 
 advanced life. The reasons for thinking it adapted to the 
 peculiar wants of the old have been given, and will be 
 found sufficient to warrant the opinion put forward. 
 
 To attempt to classify the nervous maladies of old age 
 and to give the management of each would only unduly 
 swell the size of this pamphlet without adding to its 
 value. The great matter to be grasped is essentially 
 the treatment indicated by what we observe in life, and 
 what is revealed in the dead-house as to the changes 
 wrought by age. It stands out clearly before us. We 
 must get these people to husband their powers, and yet 
 not to lead too sedentary a life by which the already 
 imperfect oxidation and removal of waste products is 
 favoured. Also by a suitable dietary to avoid the ac¬ 
 cumulation of waste products in the blood. Then to 
 administer remedial agents which will feed the nervous 
 tissue so as to keep at bay that widespread deteriora¬ 
 tion of it which age brings with it. These principles 
 apply to all cases; and that hebetude which creeps 
 slowly over the old is to be borne in mind—no matter 
 what the special ailment complained of, or the symp¬ 
 toms for which relief is sought. Senile degeneration is 
 the main fact to bear in mind in dealing with aged 
 persons. The tissues are comparatively easily injured,. 
 
28 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 while repair is tardy and often imperfect. The great 
 matter then is to take such measures and precautions 
 as shall -\vard off any positive malady, and, so far as lies 
 in our power, to prevent what we cannot cure. The 
 whole viscera are structurally impaired by the wasting 
 of their proper elements, and the growth of their con¬ 
 nective-tissue ; in other words a general visceral cirrhosis 
 is developed, by which their functional activity is impaired 
 and consequently the demand upon them must be re¬ 
 duced to their capacities. They are not in a condition to 
 bear strain, or tolerate injury or demand upon them. 
 It becomes most desirable to maintain the health and 
 vigour so far as this may be done, and no medicinal 
 combination yet devised will be found to serve this 
 desirable end so well and so effectually as the syrup of the 
 hypophosphites offered to the world by Mr. Fellows. At 
 least this is his sincere belief, and in corroboration of 
 what is written here he begs to offer to his readers the 
 following letters, as a few of the large number which 
 have been addressed to him on the subject. 
 
 Before proceeding to do so, however, he must draw 
 attention to one particular subject, and that is that not 
 unfrequently he receives complaints that certain skin- 
 troubles seem to be increased by the use of the syrup, such 
 as eczema scroti for instance. There is no doubt that at 
 times such is the case; but if there is an increase of local 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 21> 
 
 irritation it is more than compensated for by the improve¬ 
 ment of the general health. MacLachlan states that 
 where cutaneous discharges have existed for some time 
 and then dried up amongst his aged patients at the 
 Chelsea Hospital, applications have frequently been made 
 to him to reinstitute them as being useful. In speaking 
 of eczema he writes: “That the eruption is occasionally 
 and not unfrequently salutary there can be no doubt, 
 and the cure of chronic eczema is sometimes succeeded, 
 as in other chronic cutaneous symptoms, by severe pec¬ 
 toral ailments, and still more alarming cephalic symp¬ 
 toms, vertigo and apoplexy itself.” There are then some 
 matters which are “best out,” and there certainly are 
 some cutaneous matters which apparently are aggravated 
 by the use of the syrup, of which this is true. Probably 
 however these very eruptions exercise a beneficial effect 
 upon the general health. 
 
 From experience covering many years in the use of 
 his Hypophospliites, Mr. Fellows begs to remind the 
 profession of its higher utility when united with Cod 
 Liver Oil in an emulsion, as directed on p. 72 . Not only 
 are the nutritive and. tonic properties very much in¬ 
 creased thereby, but the oil is converted into a 'palatable 
 food. In this form a surprisingly beneficial effect is 
 produced upon the general health of the aged. This is 
 particularly apparent in cases of bronchial difficulty. 
 
.30 SOME CONDITIONS OF ADVANCED LIFE. 
 
 CLX. 
 
 From S. A. Kelley, Esq., M.D. 
 
 Rileyville, Pa., U.S.A., 
 Dear Sir, Dec. 19, 1880. 
 
 , I prescribed your Hypophospliites to Mrs.-, 
 
 set. 52, wife of a wealthy farmer. She had previously 
 two severe attacks of “ pleuro-pneumonia,” last April 
 typhoid fever and oedema of the lungs, since which she 
 has never seemed compos mentis. Constantly troubled 
 by some Phantasm or Hallucination, and at the same 
 time fretful, without energy, and a desire for self- 
 destruction, as life was to her a terrible burden. 
 Happily, all these troubles have disappeared since she 
 began the use of the Hypophospliites, and she appears 
 to be fully restored to health. 
 
 S. A. KELLEY, M.D* 
 
 To Mr. Fellows. 
 
 CLXI. 
 
 From John Lake, Esq., M.D. 
 
 Rehobeth, S.C., U.S.A. 
 
 Dear Sir, 4 July , 1881. 
 
 Some time ago I began using your Hypophos- 
 phites, and with the most happy results. My whole 
 
FELLOWS' SYBUP OF THE HYPOPHOSPHITES. 31 
 
 system was prostrated by “Chronic Diarrhoea,” to which 
 I had been a victim since the late war, and was running 
 down very rapidly when I began its use ; it has fulfilled 
 every promise made in your circular. My bowels are in a 
 better condition than for many years, the muscular and 
 nervous tissues built up and strengthened far beyond my 
 hopes. I believe your Syrup of Hypophosphites will 
 soon become a standard prescription in Nervous and 
 General Debility. Great precautions, however, should 
 be taken to prevent its being counterfeited. Thanking 
 you for the great benefit I have derived, 
 
 I am, Sir, 
 
 Yours truly, 
 
 JOHN LAKE, M.D. 
 
 CLXII. 
 
 From R. D. Purefoy, Esq., M.B.T.C.D., F.R.C.S.I., 
 Obs. Surg. Adelaide Hosp., Lee. on Mat. Med. Led. 
 Sch. Med. 
 
 18, Merrion Sq., Dublin, 
 19, Sept., 1884. 
 
 I have frequently had recourse to the use of Fellows’ 
 Hypophosphites in cases of debility, especially when 
 
32 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 attendant on chronic uterine diseases, and believe it fully 
 deserves the encomiums so widely bestowed on it. 
 
 R. D. PUREFOY. 
 
 CLXIII. 
 
 Translation of a letter from Dr. Bruno Bayona. 
 
 Ablitas, Navarra, Spain, 
 7 June , 1884. 
 
 Dear Sir, 
 
 With great satisfaction, I have used your Syrup 
 of Hypopliospliites in a case of bronchial asthma; 
 indeed, I have seen verified all that you promised us, 
 and have great pleasure in telling you that your Syrup 
 replaces with great advantages all remedies which we 
 have used in cases of this kind. It stopped the 
 paroxysms and brought about tranquility of sleep, 
 sleeplessness troubling my patient most before she 
 took the Syrup. 
 
 Yours truly, 
 
 BRUNO BAYONA, M.D. 
 
 Mr. Jas. I. Fellows, London. 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 33 
 
 CLXIV. 
 
 From Dr. D. J. King. 
 
 Kio de Janeiro, Brazil, 
 
 12 Aug., 1884. 
 
 Dear Sir, 
 
 When the vital powers are lowered by long 
 residence in this country, I have prescribed (and con¬ 
 tinue to do bo) your Syrup of Hypophosphites with 
 marked benefit. I find it a good tonic for European 
 children also. 
 
 Yours very truly, 
 
 D. J. KING, M.D. 
 
 Mr. Jas. I. Fellows, London. 
 
 CLXY. 
 
 From Wm. R. Goodfellow, M.R.C.S., L.S.A. 
 
 Roche, Cornwall, England, 
 
 / 28 Aug., 1884. 
 
 Mr. James I. Fellows. 
 
 Dear Sir, 
 
 Your Syrup has been used for some time in my 
 practice, and I am pleased to say with extremely satis¬ 
 factory results ; indeed, I have succeeded (whilst pre¬ 
 scribing it) in cases when the administration of the 
 
 C 
 
34 SOME CONDITIONS OF ADVANCED LIFE. 
 
 various ingredients of your Syrup in uncombined form 
 have signally failed, and now I invariably use your 
 formula and believe that it assimilates better. 
 
 It has proved with me to be most efficacious in all 
 cerebral and general affections of the nervous system. 
 
 My rule is to abstain from giving testimonials, this 
 being the only exception, but I consider that the subject 
 merits this. 
 
 Yours truly, 
 
 Wm. e, goodfellow. 
 
 CLXVI. 
 
 From Charles Fairfax Nursey, Esq., L.B.C.P.Ed., 
 
 L.M., L.F.P.S.Glas. 
 
 1, Cambridge Terrace, 
 
 Talham Street, 
 
 Sunderland, England. 
 
 Dear Sir, 
 
 I have used your preparation with much 
 success, particularly in the case of my own son, a boy 
 about nine years of age, who for some time has 
 suffered from anaemia, general weakness and lassitude, 
 due to threatened spinal curvature. I gave him 
 frequent doses of your Syrup, which in a short time 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 35 
 
 restored his strength. I should prescribe your remedy 
 oftener than I do, if the price would allow my patients 
 to purchase it, yet I order it because it is a valuable 
 compound, far better than anything of the kind in the 
 Pharmacopeia. 
 
 I am, yours very truly, 
 CHARLES FAIRFAX NURSEY. 
 
 clxvii: 
 
 From A. E. Abrams, Esq., M.D. 
 
 / _ | 
 
 164, High Street, 
 
 Hartford, Connecticut, U.S.A., 
 
 Oct. 8, 1884. 
 
 James I.. Fellows, Esq. 
 
 Dear Sir, 
 
 The Syrup Hypophos Co. (Fellows') has proved 
 of great benefit to my wife. It strongly confirms my 
 experience of its value during the past two years. 
 
 Yours truly, 
 
 A. E. ABRAMS. 
 
86 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 CLXVIII. 
 
 From E. Jay Fisk, Esq., M.D. 
 
 75, Third Street, 
 
 Troy, New York, 
 
 Oct. 6, 1884. 
 
 James I. Fellows, Esq. 
 
 Dear Sir, 
 
 I dispense your Syrup Hypoplios, Comp, and 
 now use no other, as I claim and prove your Syrup to 
 have no equal. 
 
 Yours truly, 
 
 E. JAY FISK. 
 
 CLXIX. 
 
 From Gf. A. Bjoerkman, Esq., M.D. 
 
 61, Camden Street, 
 
 Boston, Mass., U.S.A., 
 
 December 25, 1884. 
 
 James I. Fellows, Esq. 
 
 Dear Sir, \ 
 
 I am exceedingly pleased with the effect of your 
 Syrup, and would find it difficult, now I have learnt 
 its merits, to do without it. It is not equalled by any 
 preparation of its kind. 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 37 
 
 I liave two interesting cases to report. First case, 
 Hans Mortensen, a Swede, age 24, fell from a height of 
 40 feet, breaking his fall by striking against a balcony. 
 He suffered from concussion of the brain, and probably 
 of the spine, as the result of the fall; also three scalp 
 wounds and a sprained wrist. The external wounds 
 healed rapidly under appropriate treatment, but he 
 grew weaker day by day, lost weight, and suffered from 
 constipation. I tried various courses of treatment— 
 Iron, Quinine, Bark, &c., but he got steadily weaker, 
 and three months after the accident could do little but 
 lie about on a lounge. I then tried a course of 
 electricity with strychnine internally, but to no pur¬ 
 pose. It at last occurred to me to try your Syrup, and 
 I commenced with one teaspoonful three times a day 
 with his meals. I used no other treatment, and very 
 soon there was marked improvement, the appetite 
 returning and vitality increasing. After two weeks’ 
 treatment he began to increase in weight at the rate of 
 about 1 lb. a week. At the end of three months he 
 declared himself to be stronger and healthier than he 
 had ever been. He now weighs 158 lbs., his highest 
 weight at any time previous to the accident not having 
 exceeded 146 lbs. 
 
 I can truly say that I owe not only the recovery but 
 the life of this man to the valuable properties of your 
 
38 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 Syrup, which has also been of incalculable service to> 
 me in the treatment of many cases of anaemia and 
 pulmonary disease. 
 
 It is an excellent prophylactic to take in districts 
 
 t 
 
 where there is bad drainage. 
 
 As an instance, I quote a family who lived in such a 
 district, and who one and all suffered from constant 
 sore throats and gastric irritation. Since they have 
 taken your Syrup they have been entirely free from the 
 above troubles and have grown much stronger. 
 
 I remain, dear Sir, 
 
 Yours very truly, 
 
 G. A. BJOERKMAN. 
 
 CLXX. 
 
 From J. W. Jordan, Esq., M.D. 
 
 Black Hawk, Missouri, 
 
 January 9, 1885." 
 
 James I Fellows, Esq. 
 
 Dear Sir, 
 
 I have used your Syrup Hypoplios. Co. for twe 
 years with the happiest results. I have found it to be 
 especially beneficial in the incipient stage of Phthisis 
 Rulmonalis, in Bronchitis, and in all cases of nervous 
 
 I 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 39 
 
 debility. I consider it highly beneficial in chronic 
 wasting diseases. 
 
 Yours truly, 
 
 J. W. JORDAN. 
 
 CLXXI. 
 
 From J. Harmison^ Esq., M.D. 
 
 Cuba, Dec. 15, 1884. 
 
 James I. Fellows, Esq., 
 
 Dear Sir, 
 
 About a fortnight ago I received and read 
 your valuable treatise, part 4. I have used your 
 Syrup Hypop. Co. for about three years in incipient 
 Phthisis, and other forms of lung mischief. For 
 
 t „ i 
 
 instance, my own mother, who was suffering from 
 Fibroid Phthisis, and whose case was adjudged hopeless, 
 all the ordinary remedies having proved futile, recovered 
 under treatment by your Syrup. Another case of 
 severe lung disease following measles was treated 
 similarly, with favourable results. I might .multiply 
 cases, but it is useless. I think your remedy the most 
 valuable for the purposes claimed for it that can be 
 obtained. 
 
 Yours truly, 
 
 J. HARMISON. 
 
40 
 
 SOME CONDITIONS OF ADVANCED LIFE . 
 
 CLXXII. 
 
 (Translated ). 
 
 From Sig. V. Guzman, M.D. 
 
 Granada, Spain, 
 Feb. 7, 1885. 
 
 James I. Fellows, Esq. 
 
 Dear Sir, 
 
 i v 
 
 I have pleasure in stating that I have used 
 your Syrup several times in cases of Insomnia, due to 
 an irritable condition of the brain, and always obtained 
 good results. I consider the Syrup a valuable nervous 
 and alimentary tonic. 
 
 Yours truly, 
 
 V. GUZMAN. 
 
 V 
 
 CLXXIII. 
 
 From J. A. Exton, Esq., M.D. 
 
 Secretary of the Hudson Medical Society, New Jersey. 
 
 ■ Beech Street, Corner Oakwood Avenue, 
 
 Arlington, New Jersey, U.S.A. 
 James I. Fellows, Esq. 
 
 My Dear Sir, 
 
 I have been intending to write to you for some 
 time, to add my mite in praise of your valuable 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 41 
 
 f preparation, (Syrup Hypoplios. Co.) I have used it in 
 tubercular infiltration of the lung many times, with the 
 most satisfactory results ; also in abscess of the lung. 
 It is a valuable adjutant to cough mixtures. 
 
 As a remedy in the treatment of mental and nervous 
 diseases it is all that is claimed for it. 
 
 In the convalescent stage of Pneumonia, in fact 
 during the whole course of the disease, its use is by me 
 never omitted. 
 
 Very truly, 
 
 J. A. EXTON, 
 
 CLXXIV. 
 
 From Josiah Paull, Esq., M.R.C.S., L.S.A. 
 
 Camborne, Cornwall, 
 
 April 11, 1884. 
 
 Mr. Jas. I. Fellows. 
 
 Dear Sir, 
 
 I have wished to write you respecting your 
 Syrup Hypoplios. Co. for some time, which I have . 
 found particularly beneficial in several cases of lung 
 disease. 
 
 In one case especially the benefit derived was extra¬ 
 ordinary. I firmly believe this patient would have 
 
42 SOME CONDITIONS OF ADVANCED LIFE. 
 
 succumbed long ere this from exhaustion but for the 
 Hypophosphites, because his nervous system was com¬ 
 pletely shattered and his digestion sadly impaired. 
 
 I have myself taken it with benefit. 
 
 I am, yours very truly, 
 
 JOSIAH PAULL. 
 
 CLXXV. 
 
 Translation of letter from Db. Cesaee Capbena, 
 
 Campo Basso, Civita Campo Maeino, Italy. 
 
 20 th May , 1885. 
 
 Mr. James I. Fellows. 
 
 Sib, 
 
 I have pleasure in informing you that having 
 employed your Syrup of Hypophosphites for about three 
 years, I have had ample opportunities of observing its 
 effects, and declare it to be a grand preparation fur¬ 
 nished to humanity by chemical science. 
 
 I will state briefly that your Syrup of Hypophos¬ 
 phites has been of positive benefit in Chronic Bron¬ 
 chitis, in the first and second stages of Phthisis, 
 Anaemia, and nervous exhaustion of the brain. 
 
■' ' ' \ ' 
 
 FELLOWS' SYRUP OF THE HYPOPHOSPHFTES. 43 
 
 For those diseases of children for which it is recom¬ 
 mended, there is no remedy equal to it. 
 
 I can say truly that in my professional experience of 
 half a century I have not found so satisfactory a 
 remedy. In fact, your preparation is beyond praise. 
 
 I am, Sir, 
 
 Yours very truly, 
 
 CESAEE CAPEENA. 
 
 CLXXYI. 
 
 V » 
 
 From Thomas Hill, Esq., L.E.C.S.Ed. & L.M. 
 
 176, Oakfield Eoad, 
 
 Anfield Park, 
 Liverpool, England. 
 
 Dear Sir, 
 
 Your valuable Syrup of the Hypophospliites is 
 to me an inestimable treasure in a large number of 
 cases ; my sheet-anchor in nervous debility. 
 
 May I request you to send me your treatises. 
 
 I am, dear Sir, 
 
 \ 
 
 Yours faithfully, 
 
 THOMAS HILL. 
 
44 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 CLXXVII. 
 
 Letter from Samuel Maughan, Esq., M.K.C.S. 
 
 Bognor, Sussex, England. 
 
 20 th January , 1884. 
 
 Mr. Jas. I. Fellows. 
 
 SYBUP HYPOPHOS. (FELLOWS). 
 
 Sir, 
 
 The first case in which I had an opportunity of 
 prescribing the above was in one of Infantile Paralysis 
 of the lower extremities in a boy of about three years 
 of age. The treatment adopted was galvanism and the 
 internal administration of the Syrup. The general 
 health rapidly improved, and in due time nutrition and 
 power were restored. From time to time I discontinued 
 the Syrup, continuing the galvanism; in a few days I 
 discovered a diminution of tone. 
 
 The second case was in that of an elderly lady con¬ 
 valescing from Bronchial Pneumonia, mainly as a 
 nutrient. The benefit was very marked; her general 
 healthy condition speedily improved, and her lung mis¬ 
 chief cleared up. I continued its use for some months, 
 as I found my patient had an unreduced dislocation at 
 the shoulder joint of long standing. Her nervous and 
 muscular tone increased considerably, and with proper 
 exercises she acquired fair use of her arm. 
 
 The third case was in that of a strumous girl of about 
 
FELLOWS' SYRUP OF TILE HYPOPHOSPHITES. 45 
 
 13 years of age, with enlarged glands of the neck and 
 general cachectic conditions, whose family were always 
 under my care. She built up marvellously under treat¬ 
 ment, the enlarged glands gradually disappeared, and 
 she lost her cough from which she had previously 
 suffered. I subsequently treated an infant in the same 
 family suffering from Marasmus with most satisfactory 
 results ; in fact, I might add that since that date I 
 have prescribed it largely in my practice in similar 
 cases to the above, in many uterine and in nearly all 
 cases of deficient nervous tone. 
 
 I am, Sir, yours faithfully, 
 
 SAMUEL MAUGHAN. 
 
 CLXXVIII. 
 
 Letter from A. E. Procter, Consulting Surgeon, 
 Darjiling, and Himalayan Eailway. 
 Colinton Sanatorium, Darjiling, India, 
 
 July 30, 1884. 
 
 James I. Fellows, Esq., 
 
 Sir, 
 
 In reply to your communication, I have pres¬ 
 cribed the Syr. Hypoplios. Co. (Fellows) for many years,, 
 both in the East and West Indies, and experience lias- 
 
46 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 convinced me that it is Pharmacologically superior to 
 any other preparation of the Hypopliosphites. 
 
 The neutral reaction of the Syrup, and the 
 stability of 'the solution of Strychnine (so that it is 
 never precipitated) are characteristics, the importance 
 of which cannot be over-estimated. The danger of 
 giving unscientifically prepared or prescribed combi¬ 
 nations of drugs containing a powerful poison has been, 
 unfortunately, too often demonstrated, and the acid 
 reaction of the usual Syrups of the Hypopliosphites 
 has been a bar to their use in those cases where acids 
 are contra-indicated. 
 
 You ask me in what class of cases I have used 
 the Syrup ? I have not time to enter into details, but 
 will state briefly that the cases in which I have 
 prescribed your Syrup with the most beneficial results 
 are in those of an adynamic or cachetic type, due either 
 to disease or environments, or habits tending to lower 
 the vital powers. As a counteractant of the depressing 
 and debilitating effects of a tropical climate, it stands 
 per se. 
 
 It is a valuable prophylactic and tonic in malarial 
 districts, and of marked utility as a tonic in tropical hill 
 stations, in that it increases the powers of assimilating 
 oxygen, deficient in the air at these altitudes. 
 
 Its composition indicates, and its effects prove it 
 
 7 
 
FELLOWS' SYRUP OF THE IIYPOPHOSPHITES. 47 
 
 to be. a restorative of brain and nerve tissue, winch is, 
 in the hurry and anxiety of modem life so prodigally 
 wasted. 
 
 Yours truly, 
 
 A. E. PROCTER. 
 
 CLXXIX. 
 
 Letter from Percival H. Watson, Esq., L.R.C.P., 
 Lond., M.R.C.S., Eng. 
 
 64, Jesmond Street, 
 
 Newcastle - on- T yne , 
 
 England, June 24, 1885. 
 
 Mr. J. I. Fellows. 
 
 Dear Sir, 
 
 I have much pleasure in stating that I have 
 formed a very high opinion of your Syrup of the Hypo- 
 phosphites. 
 
 I have used it extensively in a great variety of 
 diseases, and have always been pleased with the results. 
 It agrees with the most delicate stomach, and can be 
 taken for long periods by patients who cannot take 
 oven half-grain doses of quinine without producing 
 unpleasant symptoms. This I have repeatedly proved. 
 I have tried several imitations of your syrup, but 
 
48 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 they are neither so palatable nor so efficacious as 
 yours, and most of them throw doAvn a suspicious deposit 
 on standing, so that I was afraid to use the last three 
 or four ounces left in the bottles. 
 
 In a case of Epileptic Neuralgia in a lady, aged 
 sixty-three, I was much pleased with its effect, as the 
 patient greatly improved whilst taking it. 
 
 Yours truly, 
 
 PEKCIVAL H. WATSON. 
 
 (Translated from the French) 
 
 From Mons. le Docteur Mca. Bouedera, a Vic-Fezensac, 
 
 dep Gers, France. 
 
 5 March , 1885. 
 
 Sir, 
 
 Mr. Fellows has invented, without perhaps 
 himself suspecting it, the best tonic known up to the 
 
 present time. The Hypopliosphites of- have not 
 
 maintained their reputation, owing to some defect in the 
 composition or preparation, which did not assure long 
 continued relief. I am happy to tell you that I consider 
 Mr. Fellows’ preparation as the greatest benefit obtained 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 49 
 
 by modern therapeutic science. My personal experience 
 of its use has indubitably confirmed me in this opinion. 
 The effects are speedy and lasting, as it acts upon the 
 great sympathetic gastric nerves, in promoting digestion 
 and facilitating the action of the lungs. 
 
 It has no special influence upon the kidneys and 
 bladder. 
 
 I am, Sir, &c., 
 
 Mca. BOURDERA. 
 
 To Mons. B- 
 
 Paris, France. 
 
 CLXXXI. 
 
 (.Translated from the French). 
 From Monsieur le Docteur Peud’homme. 
 
 14, Boulevaed Poissonnieee, 
 Paeis, April 3, 1885. 
 
 SlE, 
 
 I have experimented with your Syrup of Hypo- 
 phosphites, and can testify to the excellent results 
 obtained. 
 
 I am, Sir, &c., 
 
 De. PEUD’HOMME. 
 
 Mons. James I. Fellows, 
 London. 
 
f 
 
 < 
 
 50 SOME CONDITIONS OF ADVANCED LIFE. 
 
 CLXXXII. 
 
 (Translated from the French). 
 
 From Monsieur le Docteur Mora, Doctor of Medicine 
 of the faculty of Paris, Medical Inspector of Children. 
 
 Laureated by several learned Societies. 
 
 A Brunchamel, Dep. Aisne, 
 
 May 2, 1885. 
 
 Sir, 
 
 (SYKUP HYPOPHOSPHITES FELLOWS.) 
 
 The use of this preparation has been followed by 
 excellent results in many cases of pulmonary phthisis ; 
 patients take it readily—an immense advantage over 
 most other medicines—and its use can be continued for 
 a considerable length of time. 
 
 Under its influence the cough becomes less 
 trying, and the expectoration easier and more abundant. 
 The composition of Fellows’ Syrup is based upon positive 
 physiological data, and will, I am convinced, meet with 
 a most favourable reception from the medical profession. 
 In my opinion, it is the best remedy that can be 
 prescribed in cases of tubercular consumption, general 
 debility, anaemia and scrofula. Of this resume of my 
 recent experiences, you are at liberty to make any use 
 you please. 
 
 I am, Sir, &c., 
 
 Dr. MORA. 
 
 Mons. James I. Fellows, London. 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 51 
 
 CLXXXIII. 
 
 (Translated from the French ). 
 
 From Mons. le Docteur Riterolles, of the Faculty of 
 Paris, formerly House-Surgeon at the Hospital of 
 Clermont—Ferrand. 
 
 La Bourboule, France, 
 
 4 June , 1885. 
 
 Sir, 
 
 As medical men should contribute towards the 
 adoption of anything tending to the relief and comfort 
 of the sick, permit me to add my tribute to that of my 
 medical brethren who have prescribed your Hypophos- 
 phites. 
 
 Having made a number of observations in your 
 favour, I am quite ready to communicate them. 
 
 These observations relate to diseases which have 
 been treated at La Bourboule by arsenical preparations 
 simultaneously with your Syrup of Hypophospliites. 
 I can confidently say that in nearly every case the 
 results have been marvellous, and much superior to 
 those obtained by arsenical remedied alone. My opinion 
 on this point is very decided. 
 
 The employment of your preparation of the Hypo- 
 phosphites with- the arsenical remedies appears to me 
 to be the only efficacious treatment in Chlorotic 
 
 D 2 
 
52 SOME CONDITIONS OF ADVANCED LIFE. 
 
 Anemia, Scrofula in all its forms, and organic affections 
 of the lungs. The two remedies employed at different 
 times have not proved so effectual in my hands. 
 
 I am, &c., 
 
 Dr, RITEROLLES. 
 
 Mons. James I. Fellows, 
 
 London. 
 
 EXTRACTS FROM PHYSICIANS’ LETTERS 
 REFERRING TO FELLOWS’ HYPO- 
 PHOSPHITES. 
 
 CLXXXIY. Acted charmingly with a lady patient 
 suffering from Pulmonary Tuberculosis. 
 
 Irvine W. Gilkeson, M.D. 
 
 21 Sept., 1881. 
 
 Mint springs, Augusta Co., 
 
 Va., U.S.A. 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 53 
 
 CLXXXY. Using it in three cases, an old man, 
 eighty years, with Neuralgia, and two young ladies, all 
 improving. 
 
 A. Neely, M.D., 
 
 4 Aug., 1881. Smitlitown, W. Va., U.S.A. 
 
 CLXXXYI. 
 
 ably. 
 
 Your Hypophospliites is working admir- 
 B. G. Cooke, M.D., 
 
 24 Oct., 1880. 117, E. 91 Street, New York City. 
 
 CLXXXVII. Superior to anything of the kind that 
 I have ever seen. 
 
 \V. L. Ivelsey, M.D., 
 
 24 Aug., 1881. Willington, Connecticut, 
 
 U.S.A. 
 
 CLXXXVI1I. I believe it a good preparation. 
 
 J. G. A. Dick, M.D., 
 Red Banks, N. C., U.S.A. 
 
 10 Mar., 1881. 
 
54 SOME CONDITIONS OF ADVANCED LIFE. 
 
 CLXXXIX. I think it an excellent preparation. 
 
 S. W. Eaton, M.D., 
 
 23 June, 1881. Eowan Mills, 
 
 N. 0., U.S.A. 
 
 CXC. I like it very much. 
 
 2 Feb., 1881. 
 
 J. E. Slingerland, M.D., 
 Mt. Lebanon, 
 
 N, Y., U.S.A. 
 
 CXCI. Have tried it and am much pleased with the 
 results obtained. 
 
 18 Mays 1881. 
 
 H. C. Eeiet, M.D., 
 
 New Baltimore, 
 
 Pa., U.S.A. 
 
 CXCII. I cordially recommend it to the medical 
 profession. 
 
 8 Sept., 1881. 
 
 E. Kendrick, M.D. 
 
 Chief Health Officer, 
 Corinth, Miss. 
 
 1 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 55 
 
 CXCIII. The best remedy I have found. 
 
 A. B. Pope, M.D. 
 
 11 Aug., 1881. Stewart, Honston Co. 
 
 Tenn., U.S.A. 
 
 CXCIY. Used with satisfactory results. 
 
 N. B. Scott, M.D. 
 
 8 July, 1881. Hagerstown, Mo. 
 
 CXCV. Proved efficacious in a number of cases. 
 
 W. W. Wilson, M.D. 
 
 17 May, 1881. Williamston, S.C. 
 
 CXCYI. Administered it to a lady patient with good 
 effect, breathing much improved. 
 
 G. W. Storey, M.D. 
 
 5 April, 1881. Santa, Jackson, Co., Ala. 
 
 CXCVII. Am using it with best results. 
 
 J. J. Barclay, M.D., 
 Wheeler, AH 
 
 6 April, 1881. 
 
56 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 CXCVIII. Much pleased with its effect in an ex¬ 
 tremely bad case of Consumption, with symptoms of 
 Paralysis and Nervous and Cerebral Exhaustion. 
 
 W. T. Hodnett, M.D. 
 
 15 June, 1881. Tuskegee, Ala. 
 
 CXCIX. Frequently employ it; always with success. 
 Know of nothing better or more reliable. 
 
 John Abercrombie, M.D. 
 
 18 May, 1881. Memphis, Tenn. 
 
 CC. Although but two-thirds of a bottle has been 
 used, I feel better than for fifteen or twenty years. 
 
 P. T. Daine, M.D., 
 
 4 June, 1881. Cleveland, Ohio. 
 
 CCI. Has given perfect satisfaction. 
 
 J. H. Decherd, M.D., 
 Van Buren, Arkansas. 
 
 30 Aug., 1881. 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 57 
 
 CCII. Physician’s Armamentarium incomplete with¬ 
 out it. 
 
 E. W. Smith, M.D., 
 
 4 Oct., 1881. Yorkville, Gibson Co., Tenn. 
 
 CCIII. Always reliable in cases of tuberculosis, 
 nervous debility and mental derangement. 
 
 M. CzARTORYSKI, M.D., 
 
 2 Mar., 1882. Stockton, Cal., U.S.A. 
 
 CCIV. Perfect satisfaction in diseases of the throat 
 and lungs. 
 
 L. C. Davis, M.D., 
 
 18 Mar., 18.82. Vassar, Michigan. 
 
 ccv. 
 
 tonic. 
 
 Have never seen anything excel this as a 
 
 I 
 
 B. M. Walker, M.D., 
 Danville, Virg., U.S.A. 
 
 22 Mar., 1882. 
 
58 
 
 SOME CONDITIONS OF' ADVANCED LIFE. 
 
 CCVI. One of the most valuable therapeutical 
 agents we now possess in the treatment of Pulmonary 
 
 / 
 
 Diseases. 
 
 E. Macfarlain, M.D., 
 
 7 Aug., 1882. 18, East 128tli Street, New York. 
 
 CCVII. Acted well in cases named; one patient 
 entirely cured of nervousness, the others benefited. 
 
 S. B. Chisholm, M.D., 
 
 23 Nov., 1882. Honeapath, S. C. 
 
 CCVIII. I certainly obtain better results from 
 Fellows’ Hypopliosphites than are observed from the 
 use of other manufactures. 
 
 A. Lwezey, M.D., 
 
 18 Dec., 1882. Yardleyville, Pa. 
 
 CCIX. Ordering your preparation almost daily. It 
 is elegant, effective, and answers fully your recom¬ 
 mendations. 
 
 Waltar B. Be yn olds, M.D. 
 10, Fifth Street, N.E., 
 
 Washington, D. C. 
 
 3 Jan., 1883. 
 
FELLOWS' SYBUP OF THE HYPOPHOSPHITES. 59 
 
 CCX. As indispensable in practice as quinine, use 
 it where a constructive alterative and general tonic is 
 indicated, always with gratifying results. I believe 
 Syr. Hypo. Co. Fellows has done more to establish my 
 reputation than all remedies in the Materia Medica 
 combined. So extraordinary and unhoped for were the 
 results of one case treated by it that I fear to relate it 
 except to friends who know me. 
 
 F. E. Daniel, M.D., 
 
 25 Jany., 1883. Fort-Wortli, Texas. 
 
 CCXI. Has worked splendidly ! With continued 
 satisfaction ! A splendid preparation ! In all cases cf 
 debility, in the first stages of consumption, and the 
 debility of old age, its effects are most satisfactory. 
 Patients increase in flesh, and improve in appetite 
 under its use. 
 
 H. W. Cobb, M.D., 
 
 9 June , 1883. Perry, Michigan. 
 
 CCXII. In all cases of Pulmonary Diseases, Scrofula, 
 Anaemia, Marasmus, find good results. 
 
 A. W. Cotten, M.D. 
 
 7 June , 1883. Baltimore, Maryland. 
 
60 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 CCXIII. Am pleased with Fellows’ Hypopliosphites 
 in cases of female nervousness and incipient phthisis. 
 
 S. R. Voorkees, M.D. 
 
 14 June , 1883. Macon, Ohio. 
 
 CCXIV. In all respects fully up to the measure 
 you claim for it. 
 
 R. W. Smith, M.D., 
 
 4 June , 1883. Yorkville, Tenn. 
 
 CCXY. A very useful tonic in nervous exhaustion, 
 for which it seems especially indicated. 
 
 Henry Herman, M.D. 
 
 May 31, 1883. New York City. 
 
 CCXYI. Am always delighted with the result 
 obtained from your Hypopliosphites. Scarcely a day 
 passes that I do not prescribe it. A valuable preparation. 
 
 B. M. Walker, M.D. 
 
 2 June , 1883. Danville, Va., U.S.A. 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. G1 
 
 I 
 
 CCXVII. Only needs a trial to prove its superiority 
 in cases of nervous or general debility, whether from 
 pulmonary or other causes. 
 
 J. E. Beeve, M.D., 
 
 15 June, 1883. Martinsburg, Texas. 
 
 CCXVIII. Still using it with excellent results. Is 
 accomplishing much good. 
 
 H. B. Pope, M.D., 
 
 2 June , 1883. Stewart, Tenn. 
 
 CCXIX. Your preparation gives excellent satisfac¬ 
 tion. 
 
 Jno. W. Hopper, M.D., 
 1 June, 1883. - Hackensack, N.J. 
 
 CCXX. Prescribe it almost daily in nervous debility 
 as well as pulmonary affections. In some cases superior 
 to all other remedies. 
 
 J. A. Jenkins, M.D., 
 Brooklyn, E.D., L.I 
 
 2 June, 1883. 
 
C2 SOME CONDITIONS OF ADVANCED LIFE. 
 
 CCXXI. Fellows’ Syrup of Hypophosphites in 
 Bronchial affections and the Marasmus of children has 
 proved most useful. 
 
 Leonard North, 
 
 Earl Street, Dublin. 
 
 CCXXII. Je m’en trouve tres bien. 
 
 > 
 
 Dr. J. Gerard, 
 
 14, Rue d’Amsterdam, 
 
 May 27, 1885. Paris, France. 
 
 CCXXIII. 
 
 From the “ New York Medical Digest,” 15 th June, 
 
 1888. 
 
 Fellows’ Hypophosphites.— This preparation for the 
 cases in which it is, indicated, in our judgment, has few 
 equals. It has become one of the essentials almost in 
 practice. We have used many bottles with great satis¬ 
 faction to ourselves and patients. 
 
FELLOWS' SYRUP OF THE HYP0PH0SPH1TES. 63 
 
 CCXXIV. 
 
 From the “Kansas Medical Index.” 
 
 Fellows’ Hypophosphites needs no word of commen¬ 
 dation from us, as it is generally prescribed by the 
 Profession. 
 
 CCXXY. 
 
 From the “Atlanta Eclectic Journal,” March, 1883. 
 
 Fellows’ Hypophosphites.— This compound has at¬ 
 tained a popularity seldom equalled, and which would 
 be impossible without merit to sustain it. 
 
 CCXXYI. 
 
 From the “ Mississippi Yalley Medical Monthly.” 
 
 Fellows’ Hypophosphites contains all the ingredients 
 necessary for the formation of a superior' stimulant and 
 tonic. We have had the most satisfactory results from 
 its use in the various forms of debility, associated with 
 or dependent upon defective assimilation. 
 
 It is especially a desirable remedy in chronic pul¬ 
 monary diseases, including tuberlosis, for which it is 
 one of our most common and satisfactory prescriptions. 
 
 I 
 
64 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 CCXXVII. 
 
 From the “Hartford Journal of Inebriety,” Hartford, 
 Conn., U.S.A., October , 1883. 
 
 Fellows’ Hypophosphites is a remedy, par excellence, 
 in the varied anaemic and neurasthenic conditions 
 following the abuse of alcohol and opium. 
 
 CCXXYIII. 
 
 From the “ Southern Clinic,” Richmond, Va., U.S.A., 
 
 December, 1883. 
 
 Fellows’ Hypophosphites.— The testimony of the 
 Profession is so universal as to the value of the Hypo¬ 
 phosphites in all wasting diseases, consumption, and 
 cancer, that we have only to say that the preparation 
 of Mr. Fellows is pure, pleasant, and reliable. 
 
 CCXXIX. 
 
 From “Handbuchder Speciellen Internen Therapie.” 
 Yon Dr. Max Salomon, Berlin, 1885. 
 
 Phthisis pulmonum. 
 
 In all stages of Phthisis, Fellows’ Compound Syrup 
 of Hypophosphites has proved very useful as a tonic 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 05 
 
 to many eminent English cliniaters, and also to me in 
 repeated trials. 
 
 \ 
 
 Catarrhus Gastricus. 
 
 Use Fellows’ Compound Syrup of Hypopliosphites. 
 
 Cirrhosis hepatitis. 
 
 Use Fellows’ Compound Syrup of Hypopliosphites 
 thrice daily, a teaspoonful in a wine-glass of cold water 
 at meals. 
 
 This remedy is composed of the Hypopliosphites of 
 Cliinin, Strychnin, Iron, Calcium, Potash and Man¬ 
 ganese. I have used it repeatedly with good result 
 as a tonic for stimulating the appetite and removing 
 nervous sleeplessness. 
 
 Tabes dorsalis, 
 
 Try Fellows’ Compound Syrup of Hypopliosphites. 
 
 Ancesthetica. 
 
 Fellows’ Compound Syrup of Hypopliosphites is espe¬ 
 cially recommended in cases of Anaemia and Neuras¬ 
 thenia. A teaspoonful at each meal in a glass of cold 
 wader. 
 
 E 
 
66 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 Paralysis — Paresis . 
 
 Fellows’ Compound Syrup of Hypophosphites, con¬ 
 taining the Hypophosphites of Chinin, Strychnin, Iron, 
 Calcium, Potash, and Manganese, I have found useful 
 in cases of wearisome Paresis of the lower extremities 
 after infectious diseases. One teaspoonful at each meal 
 in a glass of cold water. 
 
 ccxxx. 
 
 — / 
 
 Extract from an editorial in “ The Annals of Hygiene,’ 
 Philadelphia, Pens., U.S.A., October, 1884. 
 
 The special food of the brain is phosphorus, and 
 particularly is this article requisite for a brain exhausted 
 by mental worry. But we may not always derive the 
 desired results from the use of the crude drug, hence 
 various preparations have at times been offered by 
 which the efficacy of the drug has been greatly 
 enhanced. Of these numerous formulae we have used 
 many, and have had most satisfactory results (in the 
 “ mental worry ” caused by things going wrong) from 
 the use of the Syrup of the Hypophosphites, as prepared 
 by James I. Fellows. 
 
 Let us remember that we must nip mental worry in 
 
FELLOWS’ SYRUP OF THE HYPOPHOSPHITES. 67 
 
 the bud, or it may become unmanageable. Do not let 
 it pass on into mental exhaustion. We know that 
 Dr. S. Weir Mitchell treats nervous exhaustion with 
 rest and food; let us combat mental worry with the 
 same weapons—with rest and with suitable food—and 
 this preparation of phosphorus is in reality a most 
 invaluable brain food. 
 
 CCXXXI. 
 
 Translated from an article in the “ Journal Mede- 
 cine de Paris, May 10, 1885; entitled “A New 
 Treatment of Pulmonary Phthisis by Hypophos- 
 phites.” 
 
 The therapeutics of pulmonary phthisis have made 
 important progress during the last few years, and satis¬ 
 factory results in its treatment have been obtained, more 
 especially since efforts have been made to ascertain the 
 exact limits of the lesions and the reflex results which 
 they can have on the whole organ. It has been, in fact, 
 proved, that when the lesions are limited to the surface 
 or when they have destroyed a part only of the pul¬ 
 monary parenchyma, the doctor can, by the methodical 
 use of reconstituents, obtain for his patient, if not a 
 
 E 2 
 
G8 
 
 SOME CONDITIONS OF ADVANCED LIFE. 
 
 complete cure, at all events a relatively satisfactory state 
 of health. 
 
 The basis of the rational treatment of pulmonary 
 phthisis is, therefore, an efficient reconstituent remedy 
 (or medium). A great number of preparations of this 
 hind have been suggested : some with a basis of iron, 
 others of phosphorus, bark, &c., the aim of all being to 
 increase the vital energy and resist the decay of the 
 
 i . •* 
 
 organ. 
 
 A preparation much in use in England and America, 
 called by the name of its inventor, Mr. James I. Fellows, 
 consists of a clever combination of Hypophospliites, 
 whose therapeutic properties in the treatment of pul¬ 
 monary phthisis are well known. 
 
 The bases of Fellows’ Hypophospliites are potash, lime, 
 iron, manganese, phosphorus, and various tonic alkaloids, 
 such as quinine and strychnine. It is easy to see that 
 such a combination of remedies used in proper propor¬ 
 tions would have a beneficial effect in pulmonary 
 lesions. The potash and lime restore the muscular 
 and osseous system ; the iron and manganese enrich the 
 blood ; and the phosphorus increases the vital energy ; 
 while quinine and strychnine act more especially as 
 nerve tonics. 
 
 Numerous practical experiments in England and 
 America, confirmed more recently in the clinical j)ractice 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 69 
 
 of a great number of hospitals in Paris and the provinces, 
 have proved that the Hypophosphites as prepared by 
 Mr. Fellows act in phthisis and other chronic maladies 
 by stimulating the appetite and aiding digestion and 
 assimilation by strengthening the nerves and assisting 
 the constant repair of the body in wasting diseases. 
 
 The action of Hypophosphites is most rapid and bene¬ 
 ficial in cases of fibroid phthisis, in acute or sub-acute 
 phthisis, accompanied by fever and an increase of tempe¬ 
 rature ; the Syrup, combined with good food and rational 
 treatment, sometimes gives relief when all other 
 medicines have failed. 
 
 The night sweats of phthisical patients are rapidly 
 diminished by the use of Fellows’ Syrup, and those 
 cases in which hemoptysis is a marked feature are 
 greatly benefited. 
 
 We shall no longer dwell in this article on the restor¬ 
 ative properties of this Hypophosphites. We refer those 
 of our readers who wish for more ample information 
 to the numerous works which have been published on 
 this interesting question.* We have simply aimed at 
 
 * Some observations on Fellows’ Hypophosphites, Part I.; 
 Pulmonary Diseases, Part II. ; Nervous Diseases* Part III, ; 
 Children’s Diseases, Part IV. By James I. Fellows: London, 
 67, Holborn, Viaduct. 
 
70 SOME CONDITIONS OF ADVANCED LIFE. 
 
 calling the attention of medical men to a preparation of 
 which one trial will be sufficient to convince them of its 
 great therapeutic value. 
 
 CCXXXII. 
 
 Extract from an article on “ The use of Permanganate 
 of Potash in Amenorrhcea,” published in the Gynae¬ 
 cological Journal, July, 1885, page 228, by Fancourt 
 Barnes, Esq., M.D., M.B. & C.M. M.B.C.P., Lon¬ 
 don, Fellow Obs. & Med. Soc., London, Obs. Phys., 
 Great North Cent. Hospital, Phys., Chelsea Hosp. 
 for Women, British Lying-in Hospital, and Royal 
 Maternal Hospital, London. Author of various 
 works on Women’s Diseases. 
 
 London, England. 
 
 I have found the establishment of the menstrual 
 function secured in several cases lately under my care, 
 by the administration of Fellows’ Hypopliosphites. In 
 badly nourished anaemic girls, with small, ill-developed 
 uteri, the Hypopliosphites will be found to give better 
 results than the Permanganate of Potash. Occasionally 
 the alternate administration of the drugs is useful. 
 
 FANCOURT BARNES, M.D. 
 
 i 
 
FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 71 
 
 SAFEGUARDS AGAINST SUBSTITUTION. 
 
 The Fellows’ Hypophosphites is dispensed in bottles 
 containing 8 oz. and 15 oz. by measure—the address, 
 Fellows & Co., St. John, N.B., blown on—the name, 
 J. I. Fellows, St. John, N.B., in watermark upon the 
 yellow wrapper; it is hermetically corked and sealed 
 with crimson gelatine ; is heavy, slightly alkaline, has 
 a pleasantly bitter taste, and deposits a flocculent brown 
 precipitate of Hypophosphite of Manganese when left 
 undisturbed for forty-eight hours. 
 
 Note.—Though this precipitate mars the appearance, 
 its presence has been 'found imperative to its full 
 remedial effect. 
 
 By ordering f § viii, the Syrup can be dispensed in 
 the original bottle containing that quantity, when the 
 trade label may be removed and prescription-directions 
 substituted as desired. 
 
 In dispensing, the Hypophosphites should only be 
 diluted with pure Syrup or Glycerine. 
 
 PRICES. 
 
 Great Britain, Stamp included, 7$. large; 4 s. small. 
 Ireland and Colonies, without Stamp, 6$- large ; 3s. Qd. small. 
 
 United States and Canada, $ 1.50 per Bottle. 
 
 Six bottles purchased at one time may always be had for the 
 regular price of five, in any Country. 
 
 Since the Syrup is supplied to Agents, at a given uniform cost 
 in every part of the world , the price should never exceed the above 
 figures. 1 
 
72 FELLOWS' SYRUP OF THE HYPOPHOSPHITES. 
 
 PRESCRIPTIONS. 
 
 CooL Liver Oil and Hypophosphites — 
 
 Olei Jecoris Aselli, § viij. 
 
 Ovi Vitelli urtius. 
 
 Syr : Hypophos. Fellows, 3 viij, up. 
 
 Beat the yolk of egg with two teaspoonfuls of cold 
 Avater ; add the Syrup, and shake together. Lastly add 
 the Cod Liver Oil, and shake until the mixture becomes 
 milk white. 
 
 Dose for an adult—t\vo teaspoonfuls three times daily. 
 
 Soda and Rhubarb Powder.— 
 
 Pulv. Rhei. Ind : Opt. 
 
 P. Sodie Bi Carb. aa 3 ss. 
 
 P. Zingiber Opt. gr. xl. rip. 
 
 Dose for an adult—one teaspoonful in a wine-glass 
 full of cold water. For children—one quarter, half, or 
 one-third, according to age. 
 
 Stimulating Liniment.— A useful application to the 
 chest in bronchitis, asthma, and other pulmonary diffi¬ 
 culties. 
 
 01. Cajuput, 3SS. 
 
 01. Terebinth. 
 
 Acid. Acet. Fort, aa ^ j. 
 
 Ovi Yitelli unius. 
 
 Aqua q.s., up. 
 
 Beat the yolk of one fresh egg with 4 oz. of water ; add 
 the oils of cajuput and turpentine, shake well in a 
 bottle ; add the acetic acid, and lastly sufficient water, 
 to make in all 10 ozs. Shake well. 
 
INDEX. 
 
 Disease, &'c. 
 
 Authority. 
 
 Number of 
 Letter. 
 
 Page. 
 
 Anosmia . 
 
 C. Fairfax Nursey . 
 
 CLXVI. 
 
 34 
 
 
 G. A. Bjoerkman 
 
 CLXIX. 
 
 36 
 
 
 Dr. Mora . 
 
 CLXXX1I. 
 
 50 
 
 
 Dr. Riterolles . 
 
 CLXXXIII. 
 
 51 
 
 
 A. W. Cotten . 
 
 CCXII. 
 
 59 
 
 Bronchael Asthma . 
 
 Bruno Bayona . 
 
 CLXIII. 
 
 32 
 
 Bronchitis 
 
 J. W. Jordan 
 
 CLXX. 
 
 38 
 
 
 Cesare Caprena 
 
 CLXXV. 
 
 42 
 
 
 Samuel Maughan 
 
 CLXXVII. 
 
 44 
 
 Childrens Diseases. 
 
 Cesare Caprena 
 
 CLXX. 
 
 42 
 
 Cachexia 
 
 A. E. Procter . 
 
 CLXXVIII. 
 
 45 
 
 Dementia 
 
 S. A. Kelley 
 
 CLXV. 
 
 30 
 
 
 Wm. R. Goodfellow . 
 
 CLXV. 
 
 33 
 
 Debility . 
 
 R. D. PuRFOY 
 
 CLXII. 
 
 31 
 
 John Lake . 
 
 CLXI. 
 
 30 
 
 
 D. J. King . 
 
 CLXIV. 
 
 33 
 
 
 C. Fairfax Nursey . 
 
 CLXVI. 
 
 34 
 
 
 G. A. Bjoerkman 
 
 CLXIX. 
 
 36 
 
 
 J. W. Jordan 
 
 CLXX. 
 
 38 
 
 
 A. E. Procter . 
 
 CLXXVIII. 
 
 45 
 
 
 Dr. Mora . 
 
 CLXXXII. 
 
 50 
 
 
 H. W. Cobb 
 
 CCXI. 
 
 59 
 
 
 J. R. Reeve 
 
 CCXVII. 
 
 61 
 
 
 J. A. Jenkins 
 
 CCXX. 
 
 61 
 
 Diarrhoea ( Chronic ) 
 
 John Lake . 
 
 CLXI. 
 
 30 
 
 Digestion 
 
 General Commenda- 
 
 Dr. Mca. Bourdera, . 
 
 CLXXX. 
 
 48 
 
 tions . 
 
 A. E. Abrams 
 
 CLXVII. 
 
 35 
 
 
 E. J. Fisk . 
 
 CLXVIII. 
 
 36 
 
 
 A. E. Procter . 
 
 CLXXVIII. 
 
 45 
 
74 
 
 INDEX. 
 
 Disease, &c. 
 
 Authority. 
 
 Number of 
 Letter. 
 
 Page. 
 
 General Commenda- 
 
 Dr. Mca. Bourdera . 
 
 CLXXX. 
 
 48 
 
 tions (continued) 
 
 Dr. Prud’homme. 
 
 CLXXXI. 
 
 49 
 
 B. G. Cooke 
 
 CLXXXVI. 
 
 53 
 
 
 W. L. Kelsey . 
 
 CLXXXVII. 
 
 53 
 
 
 J. G. A. Dick 
 
 CLXXXVIII. 
 
 53 
 
 
 S. W. Eaton 
 
 CLXXXIX. 
 
 54 
 
 
 J. K. Slingerland 
 
 CXC. 
 
 54 
 
 
 H. C. Beiet 
 
 CXCI. 
 
 54 
 
 
 E. Kendrick 
 
 CXCII. 
 
 54 
 
 
 A. B. Pope. 
 
 CXCIII. 
 
 55 
 
 
 N. B. Scott 
 
 CXCIV. 
 
 55 
 
 
 W. W. Wilson . 
 
 cxcv. 
 
 55 
 
 
 G. W. Storey . 
 
 CXCVI. 
 
 55 
 
 
 J. J. Barclay 
 
 CXCVII. 
 
 55 
 
 
 Jno. Abercrombie 
 
 CXCIX. 
 
 56 
 
 
 P. T. Daine 
 
 cc. 
 
 56 
 
 
 J. H. Decherd . 
 
 CCI. 
 
 56 
 
 
 B. W. Smith 
 
 CCII. 
 
 57 
 
 
 A. Lwezey 
 
 CCVIII. 
 
 58 
 
 
 W. B. Beynold?. 
 
 CCIX. 
 
 58 
 
 
 F. E. Daniel 
 
 ccx. 
 
 59 
 
 
 B. W. Smith 
 
 CCXIV. 
 
 60 
 
 
 B. M. Walker . 
 
 CCXVI. 
 
 60 
 
 
 H. B. Pope 
 
 CCXVIII. 
 
 61 
 
 
 J. W. Hopper 
 
 CCXIX. 
 
 61 
 
 
 Dr. J. Gerard . 
 
 CCXXII. 
 
 62 
 
 Insomnia 
 
 Bruno Bayona . 
 
 CLXIII. 
 
 32 
 
 
 V. Guzman. 
 
 CLXXII. 
 
 40 
 
 Malaria . 
 
 G. A. Bjoerkman 
 
 CLXIX. 
 
 36 
 
 Mental Mischief 
 
 J. A. Exton 
 
 CLXXIII. 
 
 40 
 
 Cesare Caprena 
 
 CLXXV. 
 
 42 
 
 
 A. E. Procter . 
 
 CLXXVIII. 
 
 45 
 
 
 W. T. Hodnett . 
 
 CXCVIII. 
 
 56 
 
 
 M. CZARTORYSKI. 
 
 CCIII. 
 
 57 
 
 Medical Journals . 
 
 N. Y. Medical Digest 
 Kansas Medical In- 
 
 CCXXIII. 
 
 62 
 
 
 DEX. 
 
 Atlanta Eclectic 
 
 CCXXIV. 
 
 63 
 
 
 -Journal . 
 
 ccxxv. 
 
 63 
 
INDEX. 
 
 75 
 
 Disease, &c. 
 
 Authority. 
 
 Number of 
 Letter. 
 
 Page. 
 
 Medical Journals 
 ( continued ) 
 
 Miss. Val. Medical 
 Monthly 
 
 CCXXVI. 
 
 03 
 
 
 Hartford Journal of 
 Inebriety 
 
 CCXXVII. 
 
 64 
 
 
 Southern Clinic 
 
 CCXXVIII. 
 
 04 
 
 
 Handbuch der Spec. 
 Inter. Therapie 
 
 CCXXIX. 
 
 64 
 
 
 Annals of Hygiene . 
 
 CCXXX. 
 
 00 
 
 
 Journ. Med. Paris 
 
 CCXXXI. 
 
 67 
 
 
 Gyncecological Journ. 
 
 CCXXXII. 
 
 70 
 
 Marasmus 
 
 G. A. Bjoerkman 
 
 clnix. 
 
 36 
 
 
 J. W. Jordan 
 
 CLXX. 
 
 38 
 
 
 Samuel Maughan 
 
 CLXXVII. 
 
 44 
 
 
 H. W. Cobb 
 
 CCXI. 
 
 59 
 
 
 A. W. COTTEN . 
 
 CCXII. 
 
 59 
 
 
 Leonard North . 
 
 CCXXI. 
 
 62 
 
 Nervous . 
 
 W. R. Goodfellow . 
 
 CLXV. 
 
 33 
 
 
 Y. Guzman. 
 
 CLXXII. 
 
 40 
 
 
 Josiah Paull 
 
 CLXXIV. 
 
 41 
 
 
 Thomas Hill . , 
 
 CLXXVI. 
 
 43 
 
 
 Samuel Maughan 
 
 CLXXVII. 
 
 44 
 
 
 W. T. Hodnett . 
 
 CXCVIII. 
 
 56 
 
 
 M. CZARTORYSKI. 
 
 CCIII. 
 
 57 
 
 
 S. R. Chisholm . 
 
 CCVII. 
 
 58 
 
 
 S. R. Voorkees . 
 
 CCXIII. 
 
 60 
 
 
 Henry Herman . 
 
 ccxv. 
 
 60 
 
 
 J. A. Jenkins 
 
 ccxx. 
 
 61 
 
 Neuralgia 
 
 Percival H. Watson . 
 
 CLXXIX. 
 
 47 
 
 
 A. Neely . 
 
 CLXXXV. 
 
 53 
 
 Opium and Alcohol. 
 
 Journal of Inebriety 
 
 CCXXVII. 
 
 64 
 
 Paralysis 
 
 Samuel Maughan 
 
 CLXXVII. 
 
 44 
 
 Phthisis . 
 
 J. W. Jordan 
 
 CLXX. 
 
 38 
 
 
 J. Harmison 
 
 CLXXI. 
 
 39 
 
 
 J. A. Exton 
 
 CLXXIII. 
 
 40 
 
 
 Josiah Paull 
 
 CLXXIV. 
 
 41 
 
 
 Cesare Caprena. 
 
 CLXXV. 
 
 42 
 
 
 Dr. Mora . 
 
 CLXXXII. 
 
 50 
 
 
 J. W. Gilkeson . 
 
 CLXXXIV. 
 
 52 
 
 
 W. T. Hodnett . 
 
 CXCVIII. 
 
 56 
 
76 
 
 INDEX. 
 
 Disease, &c. 
 
 Authority. 
 
 Number of 
 Letter. 
 
 Page. 
 
 Phthisis (continued ) 
 
 M. CzARTORYSKI . 
 
 CCIII. 
 
 57 
 
 
 H. W. Cobb 
 
 CCXI. 
 
 5'J 
 
 
 S. R. Yoorkees . 
 
 CCXIII. 
 
 60 
 
 Pulmonary 
 
 G. A. Bjoerkman 
 
 CLXIX. 
 
 38 
 
 
 Samuel Maughan 
 
 CLXXVII. 
 
 44 
 
 
 A. W. COTTEN 
 
 CCXII. 
 
 59 
 
 
 J. A. Jenkins 
 
 ccxx. 
 
 61 
 
 Pneumonia 
 
 J. A. Exton 
 
 CLXXIII. 
 
 40 
 
 
 Samuel Maughan 
 
 CLXXVII. 
 
 44 
 
 Strumous 
 
 Samuel Maughan 
 
 CLXXVII. 
 
 44 
 
 
 Dr. Mora . 
 
 CLXXXII. 
 
 50 
 
 
 Dr. Riterolles . 
 
 GLXXXIII. 
 
 51 
 
 
 A. W. CoTTEN . 
 
 CCXII. 
 
 59 
 
 Throat and Chest . 
 
 L. C. Davis 
 
 CCIV. 
 
 57 
 
 Tonic 
 
 B. M. Walker . 
 
 ccv. 
 
 57 
 
 
 F. E. Daniel 
 
 ccx. 
 
 59 
 
 
 Henry Herman. 
 
 ccxv. 
 
 60 
 
 
 D. J. King . . 
 
 CLXIV. 
 
 33 
 
INDEX 
 
 OF MEDICAL LETTERS TO BE FOUND IN 
 PARTS I, II, III, AND IV. 
 
 * i 
 
 Medical Authority. 
 
 1 
 
 Address. 
 
 Disease. ' 
 
 Book. 
 
 Page. 
 
 Addy, H. G. . 
 
 Canada 
 
 Nervous Disease . 
 
 1 
 
 58 
 
 Allen, David J. . 
 
 London 
 
 Children's Diseases 
 
 4 
 
 48 
 
 
 Do. 
 
 Phthisis. 
 
 4 
 
 48 
 
 Anglada, Farriols 
 
 Spain . 
 
 Bronchitis 
 
 4 
 
 43 
 
 
 Do. 
 
 Dyspepsia 
 
 4 
 
 43 
 
 ff ff 
 
 Atlanta Eclectic 
 
 Do. 
 
 Nervous Diseases . 
 
 4 
 
 43 
 
 Medical Journal 
 
 U.S.A. 
 
 Commendatory 
 
 4 
 
 57 
 
 Baines, J. K. 
 
 England 
 
 Phthisis. 
 
 4 
 
 33 
 
 If • • 
 
 Do. . 
 
 Bronchitis 
 
 4 
 
 33 
 
 Bateley, R. Godfrey . 
 
 Do. . 
 
 Nervous . 
 
 3 
 
 50 
 
 Eartlett, Edward 
 
 London 
 
 General . ' . 
 
 2 
 
 41 
 
 Bernard, Walter 
 
 Ireland 
 
 Phthisis. 
 
 2 
 
 42 
 
 Bigelow, J. M. 
 
 U.S.A. 
 
 Do. ... 
 
 2 
 
 53 
 
 Birm. Med. Review 
 
 England 
 
 Do. ... 
 
 2 
 
 27 
 
 Black, James 
 
 P<?. . 
 
 Children's Diseases 
 
 4 
 
 37 
 
 Blake, A. H. 
 
 London 
 
 Insomnia 
 
 4 
 
 39 
 
 9) ... 
 
 Do. . 
 
 Nervous Diseases . 
 
 4 
 
 39 
 
 If ... 
 
 Do. . 
 
 Senile Debility 
 
 4 
 
 39 ' 
 
 Brinton, Wilmer . 
 
 U.S.A. 
 
 General . 
 
 3 
 
 415 
 
 Browne, H. P. 
 
 Ireland * . 
 
 Insomnia 
 
 4 
 
 42 
 
 
 Do. 
 
 Nervous Diseases . 
 
 4 
 
 42 
 
 Browne, Lennox . 
 
 Lond n 
 
 General . 
 
 1 
 
 50 
 
 Brown, Gossett . 
 
 Do. . . 
 
 Bronchitis • . 
 
 2 
 
 38 
 
 Br. Med. Journal 
 
 Do. 
 
 Phthisis. 
 
 1 
 
 17 
 
 Bryan, F. C. . 
 
 Ehgland 
 
 Pulmonary . 
 
 2 
 
 42 
 
 Buffalo Journal. 
 
 U.S.A. 
 
 Do. 
 
 1 
 
 18 
 
 Callaway & Gripley . 
 
 Missouri 
 
 Do. 
 
 1 
 
 34 
 
 Carreras, Juan Viura y 
 
 Spain . 
 
 Bronchitis 
 
 4 
 
 35 
 
 Chesnf.y, K. Arn . 
 
 Virginia 
 
 Pulmonary 
 
 2 
 
 48 
 
 Christiansen, E. . 
 
 Iowa . 
 
 Do. 
 
 3 
 
 47 
 
 Clarke, Stephen J. 
 
 New York . 
 
 Do. 
 
 3 
 
 47 
 
 Clay, Edward 
 
 Canada 
 
 Do. 
 
 1 
 
 32 
 
 Collignon, H. F. . 
 
 Belgium 
 
 Neryous . 
 
 1 
 
 40 
 
 Crane, Chandler. 
 
 Canada 
 
 Pulmonary . 
 
 1 
 
 ' 35 
 
 Craig, R. 
 
 Scotland 
 
 Do. 
 
 2 
 
 48 
 
 
 Do. 
 
 Bronchitis 
 
 2 
 
 48 
 
 Croker, George . 
 
 Ireland 
 
 Pulmonary . 
 
 3 
 
 40 
 
 i 
 
78 
 
 INDEX . 
 
 Medical Authority. 
 
 Address. 
 
 Disease. 
 
 Book. 
 
 Page. 
 
 Crossby, J. Parker 
 
 
 England 
 
 
 
 General . 
 
 1 
 
 28 
 
 Crocker, J. . 
 
 . 
 
 Do. . 
 
 
 
 Do. .... 
 
 1 
 
 27 
 
 OULBREATH, W. A.. 
 
 # 
 
 South Carolina 
 
 # 
 
 Do. 
 
 2 
 
 49 
 
 Day, E. J. 
 
 . 
 
 England 
 
 
 
 Melancholia . 
 
 1 
 
 29 
 
 Davis, L. C. . 
 
 . 
 
 U.S.A. 
 
 
 . 
 
 Pulmonary . 
 
 2 
 
 43 
 
 Denton, E. W. 
 
 . 
 
 England 
 
 
 . 
 
 Do. 
 
 1 
 
 43 
 
 
 
 
 
 
 Children born in 
 
 
 
 Douglas, A. E. 
 
 
 Ireland , 
 
 
 # 
 
 Didia . 
 
 4 
 
 49 
 
 33 
 
 # 
 
 Do. . 
 
 
 . 
 
 Rickets . 
 
 4 
 
 49 
 
 
 
 Do. 
 
 
 # 
 
 Strumous Diseases 
 
 4 
 
 49 
 
 Duffey, G. F. 
 
 • 
 
 Do. 
 
 
 . 
 
 Pulmonary . 
 
 2 
 
 21 
 
 Earle, Z. S. . 
 
 . 
 
 Canada 
 
 
 . 
 
 Do. 
 
 1 
 
 31 
 
 Eklund, F. . 
 
 • 
 
 Sweden 
 
 
 . 
 
 Commendatory 
 
 4 
 
 41 
 
 Evans, C. H. . 
 
 • 
 
 U.S.A. 
 
 
 
 Nervous . 
 
 3 
 
 43 
 
 Faust, C. I. . 
 
 . 
 
 Do. 
 
 
 . 
 
 General Debility . 
 
 3 
 
 45 
 
 Felix, Jules . 
 
 • 
 
 Belgium 
 
 
 . 
 
 Paralysis 
 
 2 
 
 30 
 
 Fellows, Jas. I. . 
 
 , 
 
 London 
 
 
 , 
 
 Pulmonary . 
 
 1 
 
 14 
 
 Filson, Alex. 
 
 . 
 
 Ireland 
 
 
 
 General . 
 
 1 
 
 26 
 
 Ford, Charles 
 
 
 Scotland 
 
 
 
 Do. 
 
 2 
 
 50 
 
 33 )! 
 
 • 
 
 Do. . 
 
 
 
 Nervous and Pul- 
 
 
 
 
 
 
 
 
 monary 
 
 3 
 
 51 
 
 Fothergill, J. M. 
 
 . 
 
 London 
 
 
 
 Nervous . 
 
 1 
 
 27 
 
 Francis, Matthew 
 
 . 
 
 England 
 
 
 
 Do. 
 
 1 
 
 42 
 
 Goreham, It. V. . 
 
 . 
 
 Do. . 
 
 
 # 
 
 Bronchitis in chil- 
 
 
 
 
 
 
 
 
 dren . 
 
 2 
 
 37 
 
 
 # 
 
 Do. 
 
 
 
 Nervous . 
 
 3 
 
 49 
 
 Gostling, G. J. 
 
 • 
 
 Do. 
 
 
 • 
 
 Hcemorrhage 
 
 3 
 
 34 
 
 Hamer, J. W. 
 
 . 
 
 U.S.A. 
 
 
 . 
 
 Bronchitis 
 
 4 
 
 44 
 
 
 • 
 
 Do. . 
 
 
 . 
 
 Insomnia 
 
 4 
 
 44 
 
 Hartford Journal 
 
 OF 
 
 
 
 
 
 
 
 Inebriety . 
 
 , 
 
 Do. 
 
 
 • 
 
 A ncemia. 
 
 4 
 
 54 
 
 Haughton, It. E. . 
 
 
 Do. 
 
 
 , 
 
 Chorea . 
 
 4 
 
 43 
 
 
 , 
 
 Do. 
 
 
 
 Phthisis . 
 
 4 
 
 43 
 
 Hayes, It. E. . 
 
 
 Ireland 
 
 
 
 Phthisis and Ner- 
 
 
 
 
 
 
 
 
 vous . 
 
 3 
 
 37 
 
 Hayden, Thos. 
 
 . 
 
 Do. 
 
 
 , 
 
 General . 
 
 3 
 
 31 
 
 Hincks, J. S. H. . 
 
 . 
 
 England 
 
 
 • 
 
 Do. 
 
 3 
 
 39 
 
 Hogg, Chas. . 
 
 
 London 
 
 
 « 
 
 Nervous . 
 
 3 
 
 
 Howe, W. S. . 
 
 # 
 
 Maine 
 
 
 • 
 
 Diphtheria . 
 
 1 
 
 33 
 
 Howard, J. W. 
 
 , 
 
 England 
 
 
 • 
 
 Phthisis . 
 
 2 
 
 39 
 
 Hodgkinson, Alex. 
 
 . 
 
 Do. . 
 
 
 
 Nervous . 
 
 1 
 
 44 
 
 Hubbard, Henry W. 
 
 
 London 
 
 
 
 General . 
 
 3 
 
 33 
 
 Hughes, T. . 
 
 
 Wales . 
 
 
 # 
 
 Nervous . 
 
 1 
 
 40 
 
 Huguenin, J. G. . 
 
 # 
 
 U.S.A. 
 
 
 a 
 
 Pulmonary . 
 
 3 
 
 44 
 
 Jacobs, S. 
 
 . 
 
 Canada 
 
 
 
 Aphonia. 
 
 1 
 
 47 
 
 Jones, J. J. . 
 
 
 Arkansas 
 
 
 
 Nervous . 
 
 1 
 
 37 
 
 Jones, A. E. . 
 
 , 
 
 England 
 
 
 • 
 
 General . 
 
 3 
 
 39 
 
 Jones, Wm. . 
 
 
 Do. . 
 
 
 • 
 
 Do. 
 
 2 
 
 53 
 
 Jones, W. R. P. 
 
 
 Wales . 
 
 
 • 
 
 Nerve Nutrition . 
 
 4 
 
 37 
 
 Jordan, M. J. 
 
 
 Ireland 
 
 
 • 
 
 Debility . 
 
 2 
 
 35 
 
 Hay, J. R. 
 
 ' • 
 
 Michigan 
 
 
 • 
 
 Nerve Nutrition . 
 
 4 
 
 36 
 
 33 • • 
 
 • 
 
 Do. . 
 
 
 • 
 
 Night Sweats . 
 
 • 4 
 
 36 
 
INDEX 
 
 79 
 
 Medical Authority. 
 
 Address. 
 
 
 Disease. 
 
 Book. 
 
 ?age. 
 
 Kay, J* Rt • • 
 
 Michigan . 
 
 
 Phthisis . 
 
 4 
 
 38 
 
 
 Do. 
 
 . ’ 
 
 Pneumonia . 
 
 4 
 
 36 
 
 Kerr, Alex. S. 
 
 Ireland 
 
 . j 
 
 General . 
 
 3 
 
 29 
 
 Kettess, Dr. 
 
 Hungary 
 
 . \ 
 
 Commendatory 
 
 4 
 
 41 
 
 Lane, Jas. H. 
 
 U.S.A. 
 
 , 
 
 General . 
 
 2 
 
 49 
 
 Liv. Med.-Chir. Journ. 
 
 England 
 
 . 
 
 Commendatory 
 
 4 
 
 55 
 
 
 Do. 
 
 . 
 
 Nerve Nutrition . 
 
 4 
 
 55 
 
 London Lancet . 
 
 London 
 
 . 
 
 General . 
 
 1 
 
 17 
 
 Louisville Med. News 
 
 Louisville . 
 
 . 
 
 Children's Diseases 
 
 4 
 
 55 
 
 99 >> 99 * 
 
 Do. 
 
 # i 
 
 Phthisis . 
 
 4 
 
 55 
 
 n »» 99 • 
 
 Do. 
 
 . 
 
 Strumous Diseases 
 
 4 
 
 55 
 
 Low, W. Stuart . 
 
 England 
 
 . 
 
 Commendatory 
 
 4 
 
 42 
 
 MacfARLAN, E. 
 
 New York . 
 
 . 
 
 Pulmonary , &c. . 
 
 3 
 
 34 
 
 McKenzie, M. 
 
 U.S.A. 
 
 . 
 
 Nervous Asthenia . 
 
 2 
 
 44 
 
 McMaster, Alex. 
 
 Arkansas 
 
 . i 
 
 Nervous . 
 
 1 
 
 52 
 
 McIntire, J. P. . 
 
 Scotland 
 
 . i 
 
 Pulmonary . 
 
 1 
 
 41 
 
 McDonald, J. Alex. . 
 
 England 
 
 
 Nervous . 
 
 3 
 
 42 
 
 Madden, Thos. More . 
 
 Ireland 
 
 
 Children's Diseases 
 
 3 
 
 30 
 
 » n 99 
 
 Do. 
 
 . 
 
 Do. 
 
 4 
 
 32 
 
 99 99 99 
 
 Do. 
 
 . 
 
 Tubercular . 
 
 4 
 
 32 
 
 Malans, Boner . 
 
 Switzerland 
 
 • 
 
 Insomnia 
 
 4 
 
 34 
 
 99 99 . ' . 
 
 Do. 
 
 
 Nervous Diseases . 
 
 4 
 
 34 
 
 99 99 • * 
 
 Do. 
 
 
 Senile Debility 
 
 4 
 
 34 
 
 Marcy, H. D. 
 
 U.S.A. 
 
 • 
 
 Nervous and Pul¬ 
 monary 
 
 3 
 
 43 
 
 Masters, Jno. 
 
 England 
 
 
 Nervous Diseases . 
 
 4 
 
 33 
 
 Medical News 
 
 U.S.A. 
 
 . 
 
 Nerve Nutrition . 
 
 4 
 
 56 
 
 Med. Org., Brussels . 
 
 Belgium 
 
 • 
 
 General . 
 
 3 
 
 27 
 
 Mellor, H. H. De 
 
 India . 
 
 . 
 
 Bronchitis 
 
 4 
 
 38 
 
 99 * * 
 
 Miss. Yal. Medical 
 
 Do. 
 
 • 
 
 Phthisis. 
 
 4 
 
 38 
 
 Monthly . 
 
 Miss. Yal. Medical 
 
 U.S.A. 
 
 • 
 
 Nerve Nutrition . 
 
 4 
 
 56 
 
 Monthly . 
 
 U.S.A. 
 
 . 
 
 Phthisis . 
 
 4 
 
 56 
 
 Moore, S. J. . 
 
 Scotland 
 
 
 Nervous . 
 
 1 
 
 32 
 
 Morse, M. 
 
 New Jersey. 
 
 
 General . 
 
 1 
 
 45 
 
 Murphy, J. J. 
 
 Ireland 
 
 . 
 
 Pulmonary 
 
 1 
 
 51 
 
 Mundie, Geo. 
 
 England 
 
 . 
 
 Nervous . 
 
 2 
 
 39 
 
 Nicolson, W. P. . 
 
 U.S.A. 
 
 
 General . 
 
 3 
 
 35 
 
 Nowack, J. . 
 
 Austria 
 
 . 
 
 Insomnia 
 
 4 
 
 45 
 
 99 • 
 
 Do. 
 
 . 
 
 Nervous Diseases . 
 
 4 
 
 45 
 
 N. Y. Med. Digest 
 
 U.S.A. 
 
 . 
 
 Commendatory 
 
 4 
 
 57 
 
 Olpherts, J. W. . 
 
 Ireland 
 
 • 
 
 Nervous . 
 
 1 
 
 30 
 
 Orozoo, Francisco 
 
 Spain . 
 
 . 
 
 Commendatory 
 
 4 
 
 51 
 
 Palm, Theo. A. 
 
 Japan . 
 
 . 
 
 Nervous . 
 
 3 
 
 48 
 
 Parker, R. W. 
 
 London 
 
 . 
 
 Scrofulous 
 
 1 
 
 55 
 
 Payne, Edw. 
 
 Canada 
 
 , 
 
 General . 
 
 2 
 
 46 
 
 Perkins, J. Turner . 
 
 U.S.A. 
 
 # 
 
 Commendatory 
 
 4 
 
 40 
 
 Phillips, G. C. 
 
 Mississippi . 
 
 . 
 
 Malaria . 
 
 1 
 
 42 
 
 Press and Circular . 
 
 London 
 
 . 
 
 General . 
 
 1 
 
 24 
 
 Practitioner 
 
 Do. 
 
 
 Do. ... 
 
 1 
 
 18 
 
 Raeols, F. J. . 
 
 Spain . 
 
 • 
 
 Pulmonary . 
 
 3 
 
 28 
 
80 
 
 INDEX. 
 
 Mtdical Authority. 
 
 Address. 
 
 Disease. 
 
 Book. 
 
 ?age. 
 
 Rafols, Francisco J. . 
 
 Spain . 
 
 A ncemia. 
 
 4 
 
 40 
 
 JJ J) • 
 
 1)0. 
 
 Nervous Diseases . 
 
 4 
 
 40 
 
 
 DO. 
 
 Phthisis. 
 
 4 
 
 40 
 
 Read, A. W. . 
 
 U.S.A. 
 
 Neuralgic Rheu- 
 
 
 
 
 
 matism 
 
 3 
 
 36 
 
 Robertson, W. T. 
 
 England 
 
 Debility . . - 
 
 2 
 
 40 
 
 Ross, Geo. 
 
 Virginia 
 
 General . 
 
 1 
 
 53 
 
 Salmon, Jas. . 
 
 Canada 
 
 Asthma . 
 
 1 
 
 36 
 
 Scammell, L. L. . 
 
 Massachusetts . 
 
 Nervous . 
 
 1 
 
 54 
 
 Scott, J. H. W. . 
 
 Canada 
 
 Pulmonary 
 
 1 
 
 aH 
 
 Servias, Leopd. . 
 
 Belgium 
 
 Dyspepsia 
 
 2 
 
 29 
 
 Simpson, E. . 
 
 New York . 
 
 Pulmonary . 
 
 1 
 
 36 
 
 Smith, A. 
 
 Canada 
 
 Do. 
 
 1 
 
 34 
 
 Smyth, William . 
 
 Ireland 
 
 Children's Diseases 
 
 4 
 
 52 
 
 J) • • 
 
 Do. . 
 
 Nervous Diseases . 
 
 4 
 
 52 
 
 
 Do. . 
 
 Phthisis. 
 
 4 
 
 52 
 
 
 Do. 
 
 Pleuritis. 
 
 4 
 
 52 
 
 >> » • • 
 
 Do. 
 
 Strumous Diseases. 
 
 4 
 
 52 
 
 Specialist . 
 
 London 
 
 Nervous . 
 
 1 
 
 23 
 
 Star-tin, James 
 
 Do. . 
 
 Skin 
 
 2 
 
 52 
 
 Stein, R. v. . 
 
 Austria-Hungary 
 
 A naemia. 
 
 4 
 
 46 
 
 5) • 
 
 Do. . 
 
 Haemoptysis . 
 
 4 
 
 46 
 
 J) ... 
 
 Do. 
 
 Night Sweats. 
 
 4 
 
 46 
 
 
 Do. 
 
 Phthisis. 
 
 4 
 
 46 
 
 Stone, W. DonnetT 
 
 London 
 
 Commendatory 
 
 4 
 
 53 
 
 St. Louis Journal 
 
 Missouri 
 
 Cerebral Anaemia . 
 
 1 
 
 19 
 
 Tait, Lawson. 
 
 England 
 
 A naemia. 
 
 1 
 
 28 
 
 Tremeame, J. 
 
 Australia 
 
 Nerve Nutrition . 
 
 4 
 
 51 
 
 Trestrail, H. E. . 
 
 England 
 
 Haemorrhage. 
 
 1 
 
 39 
 
 Times and Gazette 
 
 London 
 
 Nervous . 
 
 1 
 
 21 
 
 Tinsley, A. . 
 
 Maryland . 
 
 General . 
 
 1 
 
 46 
 
 Vesey, T. A. . 
 
 Ireland 
 
 Pulmonary . 
 
 1 
 
 48 
 
 Vincent, Osman . 
 
 London 
 
 Rachitis. 
 
 1 
 
 22 
 
 VlNDEVOGEL, J. 
 
 Belgium 
 
 Pulmonary 
 
 2 
 
 31 
 
 Wade, W. S. . 
 
 England 
 
 Haemorrhage. 
 
 1 
 
 49 
 
 Wallford, W. 
 
 London 
 
 Bronchitis 
 
 1 
 
 44 
 
 Watson, Arthur . 
 
 England 
 
 Nervous . 
 
 1 
 
 55 
 
 Wheeler, Henry C. . 
 
 U.S.A. 
 
 Commendatory 
 
 4 
 
 50 
 
 
 Do. . 
 
 Insomnia 
 
 4 
 
 50 
 
 Whistler, T. Lowe 
 
 Ireland 
 
 Commendatory 
 
 4 
 
 53 
 
 
 Do. . 
 
 Imitations 
 
 4 
 
 53 
 
 Wicks, W. C. . 
 
 England 
 
 General . 
 
 1 
 
 47 
 
 Wilson, H. B. 
 
 Maryland . 
 
 Pulmonary . 
 
 1 
 
 37 
 
 Williams, R. 
 
 U.S.A. 
 
 Angina Pectoris . 
 
 3 
 
 35 
 
 Wingate, M. W. . 
 
 Massachusetts . 
 
 Nervous Diseases . 
 
 4 
 
 50 
 
 Young, James 
 
 Scotland 
 
 Nervous . 
 
 ' 3 
 
 37 
 
 Yount, T. J. . 
 
 Indiana 
 
 Commendatory 
 
 4 
 
 54 
 
 Bradbury, Wilkinson & Co., Printers, 85, Bucklersbury, London, E.C. 
 
, ni;ivti: , .;rtv-''i ' i:ri 
 
 PRINCIPAL DEPOTS 
 
 FOE 
 
 FELLOWS' HYPOPHOSPHITES. 
 
 EUROPE. 
 
 BURROUGHS, WELLCOME & Co., London, England. 
 
 WM. HAYES & Co., Dublin, Ireland. 
 
 F.. DELCHEVALERIE, 74, Rue de Namur, Brussels, Belgium. 
 
 Ch. DELACRE, Brussels, Belgium. 
 
 A. W. GROOTE, 43, Kalverstraat, Amsterdam, Holland. 
 
 ALFRED BENZON, Copenhagen, Denmark. 
 
 GEORGE F. ULEX, 6, Stubenhuk, Hamburg, Germany. 
 
 HIJOS DE JOSE VIDAL Y RIBAS, Barcelona, Spain. 
 
 JAMES CASSELS & Co., Oporto, Portugal. 
 
 A. SAUTER, Geneva, Switzerland. 
 
 ROBERTS & Co., 5, Rue de la Paix, Paris, France. 
 
 H. ROBERTS & Co., Florence and Rome, Italy. 
 
 FRANK R. SQUIRE,’ St. Remo, Italy. 
 
 JULIUS KIRCHHOFER, Trieste, Austria-Hungary. 
 
 JOSEF Y. TOROK (Konigsgasse Nr. 12), Buda-Pesth, Hungary. 
 “ENGEL APOTHEKE ” (C. Haubner’s), Wien, Austria-Hungary 
 PHARMACIA LA SPERANTIA, Bucharest, Roumania. 
 PHARMACIA BRUS, Bucharest, Roumania. 
 
 M. B. STROM, Drammen, Norway. 
 
 A. M. BECKMAN, Stockholm, Sweden. 
 
 ALEX. NORDSTROM, Helsingfors, Finland. 
 
 CAUZUCH FRERES, Pera, Constantinople, Turkey 
 C. OLYMPIUS, Athens, Greece. 
 
 ASIA. 
 
 HENRY BALLANTYNE, Bombay, India. 
 BATHGATE & Co., Calcutta, India. 
 
 SMITH, STANISTREET & Co., Calcutta, India. 
 SINGAPORE DISPENSARY, Singapore. 
 ARTHUR J. BENTLEY, Singapore. 
 
 MAITLAND & Co., Colombo, Ceylon. 
 
 A. S. WATSON & Co., Hong Kong. 
 
 A.. S. WATSON & Co., Manilla. 
 
 MUSTARD & Co., Shanghai, China. 
 
 W. J. S SHAND, Yokohama, Japan. 
 
 RATHKAMP & Co., Batavia, Java. 
 
 [Oyer.