THE UNIVERSITY OF ILLINOIS LIBRARY 61703 C7&cL 182 . 2 . v.2 Digitized by the Internet Archive in 2016 with funding from University of Illinois Urbana-Champaign Alternates https://archive.org/details/dictionaryofprac02coop # COMPREHENDING all the most interesting improvements, from the earliest TIMES DOWN TO THE PRESENT PERIOD ; AN ACCOUNT OF THE INSTRUMENTS, REMEDIES, AND APPLICATIONS EMPLOYED IN SURGERY ; THE ETYMOLOGY AND SIGNIFICATION OF THF. PRINCIPAL TERMS: AND Numerous References to Ancient and Modern Works, forming together a “ Catalogue Raisonnee” of Surgical Literature WITH formerly surgeon to the forces; member of the royal college of surgeons; OF THE MEDICAL AND CHIHURGICAL SOCIETY OF LONDON : AND , Op THE MEDICAL SOCIETY OF MARSEILLES. OF THE COLLEGE OF SURGEONS OF EDINBURGH; PROFESSOR OF ANATOMY AM' PHYSIOLOGY TO THE VERMONT ACADEMY OF MEDICINE; AND LECTURER ON SURGICAL ANATOMY IN NEW-YORK. \ variety of original facts and observations BY SAMUEL COOPER, WITH NOTES AND AN APPENDIX. BY WILLIAM ANDERSON, N two volumes YOL. II. FROM THE FOURTH LONDON EDITION NEW-YORK ; PUBLISHED BY COLLINS &■ HANNAY, 230 PEARL-STREET 7. k J. Harper, Printers. % r Southern District of New-York, ss. BE IT REMEMBERED, That on the second day oi December, m iue tony -seventh, year of the Independence of the United States of America, Collins h Hannay, of the said District, have deposited in this office the title of a book, the right whereof they claim as proprietors, in the words following, to wit : A Dictionary of Practical Surgery : comprehending all the most Interesting Improve il ments, from the earliest times down to the present period ; an Account of the Instru- ments, Remedies, and Applications employed in Surgery ; the Etymology and Signi fication of the Principal Terms ; and Numerous References to Ancient and Modern 1 Works, forming together a “ Catalogue Raisonnee” of Surgical Literature ; with a - Variety of Original Facts and Observations, by Samuel Cooper, formerly Surgeon to ci the Forces ; Member of the Royal College of Surgeons ; of the Medical and Chirur- *•' gical Society of London ; and of the Medical Society of Marseilles. With Notes and : an Appendix, by William Anderson, of the College of Surgeons of Edinburgh “ Professor of Anatomy and Physiology to the Vermont Academy of Medicine rc and Lecturer on Surgical Anatomy in New-York.” In conformity to the Act of the Congress of the United States, entitled u An Act for the encouragement of Learning, by securing the copies of Maps, Charts, and Books, to the authors and proprietors of such copies, during the times therein mentioned.” And also to an Act, entitled “ An Act supplementary to an Act, entitled An Act for the en couragement of Learning, by securing the copies of Maps, Charts, and Books, to the authors and proprietors of such copies during the times therein mentioned, and extending the benefits thereof to the arts of designing, engraving, and etching historical and other prints.” JAMES DILL, Clerk of the. Southern District o f New- York A. I c" 03 THE HORARY OF THE DICTIONARY ^ A ° 1933 ■ , F ILLINOIS; OP PRACTICAL SURGERY. P This murk (*) will signify , that the Word which it precedes is further spoken of in the Apptndix. if I O ^ HER Ue'RNTA. (From sgvoc, a branch, from its protruding forward.) Burgeons under- stahd by the term hernia, a tumour, formed by the protrusion of some of the viscera of the abdomen, out of that cavity, into a kind of sac, composed of the portion of perito- neum, which is pushed before them. How- ever, there are certainly cases which will not be comprehended in this definition ; either because the parts are not protruded at all, or have no hernial sac, as the reader will learn in the course of this article. “ The brilliant progress which surgery has made in modern times (says Scarpa) is, properly speaking, only the result of patho- logical anatomy, that is to say, of exact comparisons of the natural slate of our or- gans with their different diseases, which may depend upon an alteration of texture, a de- rangement of functions, a solution of con- tinuity, or a change of situation. It is from morbid anatomy, that the most rational curative methods, with which modern sur- gery is enriched, are deduced as so many corollaries ; methods, to which we are also indebted for the perfection of operations. “ There are indeed a certain number of surgical operations, for the prompt and sufe execution of which, mere anatomical know- ledge will suffice; but in many others, the surgeon cannot promise himselfsuccess, even though he be well acquainted with ana- tomy, unless he has particularly studied the numerous changes of position, and altera- tions of texture, of w’hich the parts, upon which he is about to operate, are susceptible. If he has not the requisite information upon all these points, false appearances may de- ceive his judgment, and make him commit mistakes, sometimes of a very serious and irreparable kind. “ In order to have a convincing proof of this truth, it will be sufficient to take a view of the different species of hernia;, and their numerous complications. Assuredly, no anatomist would believe, that the intestine ccecum, naturally fixed in the right ileum, and the urinary bladder, situated at the bot- tom of the pelvis, could undergo, without being torn, so considerable a displacement as to protrude through the abdominal ring, HER and descend even into the scrotum ; that the same intestine, the ccecuin, could pass front the right iliac region to the umbilicus, pro- trude at this opening, and form an umbili- cal hernia ; that the right colon could have been found protruded from the abdomen at the left abdominal ring, and the left colon through the right one ; that the liver, spleen, and ovary could sometimes form the con- tents of umbilical, inguinal, and femoral herniae ; that the caecum could engage itself within the colon, and even protrude at the anus ; that the stomach could be forced through the diaphragm, and form a hernia within the chest ; that the omentum, or in- testine, or both these parts together, could sometimes escape from the belly through the foramen ovale, or sacro-ischiatic notch of* the pelvis; that a noose of small intestine, after being engaged in the abdominal ring* or under the femoral arch, could suffer the most violent strangulation, without the course of Ihe intestinal matter being inter- cepted ; lastly, that in certain circum- stances, the intestine and omentum could be in immediate contact with the testicle, within the tunica vaginalis, without the least laceration of this latter membrane. These and several other analogous facts, says Scarpa, are so surprising, that they would yet he regarded as incredible, had they not been proved by numerous obser- vations on individuals affected with hernia : their possibility (repeats this experienced professor) would not even have been sus- pected, either by the anatomist or physiolo- gist.” (see Scarpa, Traitc dcs Hernits, Pref.) The parts of the body, where hernia; most frequently make their appearance, are tlm groin, the navel, the labia pudendi, and the upper and forepart of the thigh ; they do also occur at every point of the anterior part of the abdomen ; and there aro several lesle Chir. T 2, p. 344.) and an infusion of 3'j- 1° ^viij. °f water, seemed to produce sudden mortal effects in another example on record. ( Edinb . Med. and Surgical Journ. Vol. 9 ,p. 159.) Poultices and Fomentations have not the confidence of any experienced or intelligent surgeon Whoever, in these urgent cases, wastes time in trying the effects of such applications, merits censure for his credulity, ignorance, and unfitness to undertake the treatment of a rapid disease, in which, as Pott remarks, if we do not get forward, we generally go backward ; and whatever does no good, if it be at all depended upon, cer- tainly does harm, by occasioning an irre- trievable loss of time. OF THE ORDER IN WHICH THE PRECEDING METHODS AND REMEDIES SHOULD BE TRIED, AND OF THE TIME WHEN THE OPERATION SHOULD NOT BE DELAYED. In the treatment of a strangulated hernia, a surgeon cannot be too deeply impressed with the danger of spending time in the triai of methods of inferior efficacy, or of such as are evinced to be ineffectual in the cases before them. The rapidity with which gangrenous mis- chief sometimes arises, and the palien' loses his life, has been proved in a multitude of unfortunate examples, and should operate as a warning to all practitioners against the danger of deferring the operation too long. In the course of rny reading, however, I have not met with so remarkable an instance of the sudden mortification, and rapidly fatal termination of a hernia, as the follow- ing case recorded by Baron Larrey, in speaking of the fatiguing and forced marches performed by the French soldiers in Egypt. These marches, he says, brought on in one case, ‘ a hernia which formed suddenly, and became at the same time strangulated. The man was immediately brought to my ambu- lance ; but a spontaneous gangrene, which had all on a sudden attacked the intestine, and extended to the other abdominal vis- cera, caused the patient’s death in the space of two hours, and made it impossible for me to do the operation for him. This is the second example that I have been acquainted with, in which the effects of the accident were thus rapid.” ( Larrey , in Mem. de Chi- rurgie MiUlaire, T 1, p 196.) The taxis is generally among the first things to be tried, and Mr. A. Cooper thinks the attempts should be continued for a quarter or half an hour. ‘When these have been ineffectual, the patten'. if the circumstances do not forbid, should be im- mediately bled, and have a large opening made in the vein, so that the suddenness of the evacuation may be most likely to bring on fainting. The taxis should then be tried again. When the strangulation is very acute, and the patient young and strong, perhaps it may be most adviseahle to follow the advice delivered bv Scarpa and Desault, which is to bleed the patient and put him in the warm bath, before the taxis is attempted at all. If bleeding alone has been practised, and the manual efforts at reduction should not now succeed, the warm bath may be em- ployed, provided it can be got ready in a very short time, but none should ever be lost in waiting for it to be prepared. When the bath is used, the taxis may be attempted as the patient lies in the water ; a situation in which I have succeeded in reducing several herniae. Certainly not more than one hour should ever be allotted for putting in practice the first attempts at reduction, bleeding, and the warm bath. The plan should be, while the trial of one thing is going on, another should be pre- paring. So when the preceding measures have been tried in vain, the application of a bladder filled with ice, or the solution of nitre and muriate of ammonia, and the in- jection of tobacco, in the form of smoke or decoction, should never be delayed for want of due previous preparation of all the requi- sites. Both these measures should be prac- tised at the same time, immediately after the failure of the taxis, bleeding, and the warm bath. Mr. A Cooper computes, that four hours are enough for the trial of the tobacco clyster, together with cold appli- cations. In omental herniae, the necessity for ope- rating may frequently be obviated by the good effects of bleeding, purgative medi- cines, and clysters, and leeches applied to the tumour. Mr. Lawrence has justly ob- served, that “ when, as it very frequently happens, the aid of the surgeon is not requi- red until the complaint has lasted for some time, a trial of the tobacco, together with the topical use of cold, should be immedi- ately resorted to, as circumstances will not admit of delay in the previous use of less powerful remedies (P. 148, Edit. 3.) Every man who has seen much of herniae will immediately recognize the propriety of the following sentiments of the experienced Mr. Hey: “ I can scarcely press in too strong terms the necessity of an early recourse to the operation, as the most effectual method of preserving life in this dangerous disease. If Mr. Pott’s opinion be true, that the opera- tion, when performed in a proper manner, and in due time, does not prove the cause of death often er than perhaps once in fifty times; it would undoubtedly preserve the lives of many, to perform >t almost as soon as the disease commenced, without inc reasing the danger by spending much time in the HERNIA. 15 use of means which cannot be depended upon for a cure. “ I have twice seen this disease prove fatal in about twenty-four hours. In such cases, it is evident there is little time for delay. A surgeon who is competent to per- form the operation, is not perhaps consulted till the intestine is on the point of being mortified, or is actually in a state of mortifi cation. The dilemma into which he is then cast is painful indeed. But, when the fullest opportunity is afforded him of using the best mode of treatment, I am satisfied that his success will be the greatest when the opera- tion is not long delayed. This, at least, has been my own experience. When I first en- tered upon the profession of surgery, its the ear 1759, the operation for the strangulated ernia had not been performed by any of the surgeons in Leeds. My seniors in the profession were very kind in affording me their assistance, or calling me into consulta- tion when such cases occurred ; but we con- sidered the operation as the last resource, and as improper until the danger appeared imminent. By this dilatory mode of prac- tice, I lost three patients in five, upon whom the operation was performed. Having more experience of the urgency of the disease, I made it my custom, when called to a patient who had laboured two or three days under the disease, to wait only about two hours, that I might try the effect of bleeding (if this evacuation was not forbidden by some peculiar circumstances of the case) and the tobacco clyster, fn this mode of practice, I lost about two patients in nine, upon whom I operated. This comparison is drawn from cases nearly similar, leaving out of the ac- count those cases in which a gangrene of the intestine had taken place. “ I have now, at the time of writing this, performed the operation tiiirty-five times; and have often had occasion to lament that I had performed it too late, but never that I had performed it too soon. There are some cases so urgent, that it is not advisca- ble to lose any time in the trial of means to produce a reduction. The delay of a few hours may cut off all hope of success, when a speedy operation might have saved the life of the patienf. ” (P. 141, fyc.) To determine the exact moment, when to give up the trial of the preceding measures, and to have immediate recourse to the ope- ration, is certainly difficult ; but no one can doubt, that it is generally better to operate too early than too late. All directions must be general ones, liable to many exceptions : in rapid cases, little or no time should be allotted to the trial of any plan, and the operation should be done without the least delay. In other instances, we have full time to try the effects of every thing at all likely to succeed. The symp- toms, which ought to guide us, in having recourse to the operation, arise from an attack of inflammation in that part of the intestine contained in the hernial sac, and from its spreading into the abdominal cavity. It is in proportion to their violence, that we ought to urge the performance of the ope- ration. Mr. Cooper considers pain on pressing the belly, and tension, as the symp- toms w hich point out its immediate neces- sity. He adds, “ Indeed, there is scarcely any period of the symptoms, which should forbid the operation ; for, even if mortifica- tion has actually begun, the operation may be the means of saving life, by promoting the ready separation of gangrenous parts.” (O ' Inguinal and Congenital Hernia, p. 27.) Whenever the surgeon has succeeded in reducing the parts, without having recourse to the knife, if the symptoms of pain, inflam- mation, ran high before such reduction, they will not alwrays cease immediately afterward. As they probably depend on the reduced bowel having been inflamed by the stricture, the body should be kept open, and the di^ { and regimen should be low <.nd sparing, whilst the least degree of pain and tension remain ; in short, till all complaint is absolutely removed from the abdomen, and the intestines do their office freely, and without trouble. (Pott) PROGRESS OF THE SYMPTOMS OF A STRAN- GULATED HERNIA. The earliest symptoms have been already related, viz “ tumour in the groin, or scro- tum, attended with pain, not only in the part, but all over the belly, and creating a sickness and inclination to vomit, suppres- sion of stools, and some degree of fever. These are the first symptoms, and, if they are not appeased by the return of the intes- tine, that is, if ttie attempts made for this purpose do not succeed ; the sickness be- comes more troublesome, the vomiting more frequent, the pain more intense, the tension of the belly greater, the fever higher, and a general restlessness comes on, which is very terrible to bear. When this is the state of the patient, no time is to be lost; a very lit- tle delay is now of the utmost consequence, and if the one single remedy, which the disease is now capable of, be not adminis- tered immediately, it will generally baffle every other attempt. This remedy is the operation whereby the parts engaged in the stricture rnay be set free If this be not now performed, the vomiting is soon ex- changed for a convulsive hiccough, and a frequent gulping up of bilious matter; the tension of the belly, the restlessness and fever having been considerably increased for a few hours, the patient suddenly be- comes perfectly easy, the belly subsides, the pulse, from having been hard, full, and frequent, becomes low, languid, and gene- rally interrupted; and the skin, especially that of the limbs, cold and moist ; the eyes have now a languor and a glassiness, a lack- lustre not easy to be described ; the tumour of the part disappears, and the skin covering it sometimes changes its natural colour foi a livid hue; but whether it keeps or loses its colour, it has an emphysematous feel, a crepitus to the touch, which will easily be conceived bv all who have attended to it, 16 HERNIA. but is not so easy to convey an idea of by words : this crepitus is the too sure indica- tor of gangrenous mischief within. In this stale the gut either goes up spontaneously, or is returned with the smallest degree of pressure ; a discharge is made by stool, and the patient is generally much pleased at the ease he finds ; but this pleasure is of short duration, for the hiccough and the cold sweats continuing and increasing, with the addition of spasmodic rigours and subsul- tus tendinum, the tragedy soon finishes.” (Pott.) ANATOMY OF INGUINAL HERNIA. This subject must necessarily precede the account of the operation, which would other- wise be unintelligible. It is chiefly in the anatomical information, relative to herniee, and in the mode of operating, that modern surgeons have a decided superiority over their predecessors; for before Girnbernat, Camper, Hey. Lawrence, Cooper, Scarpa, and Hesselbach, published their several works on hernia?, the anatomy of the disease whs only imperfectly understood. The tendinous fibres of the aponeurosis of the external oblique muscle, as they run downwards and forwards toward , the pubes, separate from each other, so as to leave a triangular opening, called the abdominal ring, which is usually more capacious in the male than (he female subject. The upper and inner pillar (as it is termed) of this aper- ture is inserted into the symphysis of the pubes, and is the weakest of the two ; the lower and outer one, which is (he strongest, is chiefly a continuation of Poupart’s liga- menl, (Hesselbach nber den Ursprung, fyc. dtr Leisten-und-Szhenkelbruche, p. 4.) and is fixed into the angle and crista of the same bone. Some tendinous fibres cross the upper and outer angle of the ring, so as to diminish the triangular appearance of the whole aper- ture : these are said to be very strong in old hernia?. The anterior and thicker layer of the aponeurosis of the internal oblique mus- cle joins the tendon of the external oblique ; the posterior and thinner one joins that of the transversalis ; but the lower portion of this tendon, together with the corresponding part of the transversalis, goes wholly in front of the rectus muscle. Thus the inferior bor J der of the obliquus internus and transversa- lis, which originates from the upper part of Poupart’s ligament, lies behind the outer pil- lar ot the abdominal ring. Mr. A. Cooper first noticed, that a thin fascia proceeds from the inner edge of Poupart’s ligament, and spreads over the posterior surface of the transversalis. This fascia forms the only par- tition between the peritoneum and the outer opening of the abdominal ring, and were it not for it> existence, inguinal heroiae would probably be much more frequent. The par- tition in question, however, is said by Scarpa to be formed by the aponeuroses of the in- ternal oblique and transverse muscle*, while Hesselbach, who has named the small smooth point, situated directly behind (he outer opening of the abdominal ring, its crural surface , distinctly states, that it is formed by delicate fleshy and tendinous fibres of the internal oblique muscle; (Utber den Ur- sprung, fyc. der Leisten-und-Schenkelbrnche , p. 4,) and that behind them is the weakest part of what he names the internal inguinal ligament , in the rear of which is the perito- neum, with the intervention of a very loose cellular substance. (Op. cit. p. 26.) The internal inguinal ligament of Hesselbach, is therefore clearly the same thing as the above fascia pointed out by Mr. A. Cooper. This point of the abdomen is one of the three weak places on the inside of the inguinal region, where hernias are liable to occur; yet, weak as it appears to be, it is not the most common situation of such tumours. A computation has been made, that in an hun- dred cases of inguinal hernia, not ten occur at the point here specified. (H. J. Tirttnning- hausen , Unterricht uber die Bril eke, fyc. Wurzb. 1811.) The spermatic vessels, joined^by the vas deferens, run in front of the epigastric artery, very near the place of its origin. They then pass through the above fascia, go under the edge of the internal oblique and transverse muscles, and next obliquely downwards and forwards, between the above fascia, and aponeurosis of the external oblique muscle to tue opening of the ring. When arrived on the smooth surface, imcnedia : e!y behind the ring, they describe an obtuse angle, and pass forwards and downwards into the scrotum. ( Hesselbach , op. cit. p. 5.) Thus we see. that the spermatic cord, be- fore it actual emerges a' what is named the abdominal ring, runs through a kind of canal, to which the epithet inguinal is often applied. This oblique passage of the cord through the abdominal parietes, was well known to, and elegantly delineated by Albinus; Girnbernat makes distinct mention of it in his Account of a jiew Method of Operating for Femoral Hernia, p. 19, 32 ; but Mr. A. Cooper has the merit ot having given k the earliest correct ac- count of the inguinal canal, in reference to hernia ; a subject rendered complete by the more recent elucidations of Hesselbach and Scarpa. The abdominal ring is then only the outer opening of the canal, or passage, through which the spermatic cord passes betore it emerges. The inner one, at which the vis- cera first protrude in tiie most common cases ot inguinal hernia, is situated about an inch and a half from the abdominal ring, in the direction towards the anterior superior spi- nous process of the ilium ; or, according to Hesselbach, the inguinal canal is almost an inch and a half in length, the average dis- tance of the outer pillar of the abdominal ring, from the inner pillar of what he iertns the posterioi ring, being about sixteen Sines. (Op. cit. p. 14.) This inner opening is rather nearer the pubes than the ilium, and its upper horde! is formed by the lower edge ot the internal oblique, and transverse muscles, which can he plainly felt with the finger, in HERNIA, 17 Produced upward aud outward into the abdo- minal ring. u The precise point at which the hernia most commonly begins, (says Scarpa,) is that which corresponds, in lhefoetus,tothe commu- nication of the tunica vaginalis with the pe- ritoneum, and, in the adult, to the passage of the spermatic cord under the transverse muscle. In the sound state, the peritoneum presents at this part a small funnel-like de- pression, the depth of which increases in pro- portion as the spermatic cord is pulled from above downwards. It is this small pouch, this sort of digital appendage, whose pro- gressive augmentation constitutes the hernial sac. Resting upon the anterior surface of the spermatic cord, it first makes its appear- ance under the inferior edge of the trans- verse muscle ; thence if extends itself in the separation of the inferior fleshy fibres of the internal oblique muscle, always following (he spermatic cord, in front of which it is situa- ted ; and after having in this manner passed through the whole of the canal, which ex- tends from the iliac region to flic* pubes, it lastly protrudes at its external orifice, which is the inguinal (or abdominal) ring, properly so called. lu all this track, the hernial sac, ns well as the spermatic cord, is situated above file femoral arch, the direction of which it follows. The canal, which it tra- verses, is of a conical shape, the apex of which is towards the flank, and the ba-e at the external orifice of the ring.” ( Scarpa , TraiU des Hernies , p. 44, 45.) The epigastric artery runs behind the spermatic cord, along the inner margin of the interna! opening of the above canal, then upwards and inwards, so as to pass at the distance of half an inch or an inch from the upper extremity of the outer opening, or abdominal ring. In common cases of inguinal hernia, the viscera, protruded at the inner opening of t he inguinal canal, lie over the spermatic word, and form a tumour on the outside of the abdominal ring. When the viscera have entered the above described digital pouch of the peritoneum, but do not protrude through the abdominal ring, the case is sometimes termed an incom- plete inguinal hernia ; and complete when they pass out of that opening. The viscera may continue for a long while quite within the inguinal canal, and even become stran- gulated there: sometimes, also, they are prevented from passing further towards the ring by some kind of impediment; and, in this circumstance, if the hernial sac have any addition made to its contents, it may ex- pand between the external and internal ob- lique muscles, as Hesselbach bad an opportu- nity of seeing in the body of a female. { Ueher den Ur sprung, fyc. der Leisten-und- tSchenkelbriiche, p. 28.) The stricture may take place either at t tie internal or external opening of the inguinal canal. In recent and small h'-rnia, according to Mr. A. Cooper, the strangulation is most frequently situated at the inner opening ; in large old ruptures, nt the abdominal rins:'. Even when 1 he par (3 Vol. II. w ' 3 are completely protruded out of the latter opening, the strangulation may exist at the inner one; but there may occasionally be (wo strictures, viz. one at each opening. (See Lawrence on Ruptures, p. 183, I. hit. 3.) The hernial sac descends through the ab- dominal ring over (lie spermatic cord, a. I ' covered by a fascia, sent off’ from the tend of the external oblique muscle. Rem (bis fascia, the cremaster muscle is also situ- ated over the sac, which, after it '-as de- scended a certain way, lies on the tunica vaginalis, as well as the spermatic cord. As (lie epigastric artery naturally runs first behind the spermatic cord, and then along the inner margin of the internal opening of the ring, and as the viscera are protruded over the cord, they must be situated on t lie outer side of the artery, which runs first be- hind the neck of the sac, and then on its inner side. Hence, the inner margin of the sac, when inspected on the side towards the abdomen, seems to be formed, as it were, by the track of the vessel. (See Lawrence , p. 179) That this is the ordinary situation of the epigastric artery, in relation to the ingui- nal hernia, is confirmed by the concurrent testimonies of Camper, Chopart, Desault, Sabatier, A. Cooper, Hesselbach, Scarpa, &ic. and by preparations to be seen in almos 4 every museum. In recent inguinal hernia?, the internal and external openings of the ring are at some distance from each other, the first being • ated obliquely upwards and outwards to. r tion to the former; but the pressure >- protruded viscera, gradually forces the truer- rial opening more towards the pnbo and nearer to the abdominal ring, so as to r. ..b . the posterior side of the neck of the hernial sac, and of the inguinal canal, very short. ( Hesselbach . p. £9.) Thus, in large i. rroie of longstanding, the opening into the nb io- men is almost direct, and (be epigastric ; uy becomes situated nearer the pubes, than in the natural state. Though such is the ordinary direction, in which a bubonocele protrudes, (here are oc- casional varieties. In one of these, the vis- cera, instead of descending through ihe canal of the ring, are at once thrust through the abdominal ring itself, and the opening into the belly is then direct : the hernial sac, instead of passing op. the external side of the spermatic vessels, as is usual, now.iies on their inner, or pubic side ; and the epigas- tric artery, which is commonly situated be- hind, now pursues its course, in front of the sac. at its usual distance from the upper and outer angle of the abdominal ring.. The following is Scarpa's description of the displacement of the epigastric artery in the greater number of cases of inguinal her- nia. “ This artery, which in (he natural state, runs about ten lines from the abdomi- nal ring, has its situation and direction n; changed, in subjects affected with cm: a, that it crosses the posterior part ot the nock of (he hernial sac, and is pushed from the outer to the inner side of the abdominal ring. In order to comprehend the reason of this HERNIA. i3 displacement, it is necessary to recollect what I have elsewhere said of the formation of inguinal hernia, and of the manner, in which the spermatic cord crosses tiie epi- gastric artery. The hernia begins to form at the very place, where the spermatic cord passes under the inferior margin of the transverse muscle ; and this place is rather nearer the flank, than that where the epigas- tric urtery passes towards the rectus muscle. In its progressive extension, the hernial sac constantly follows the same track as the spermatic cord, since it is situated upon its anterior surface. As has been already ex- plained, this cord crosses the epigastric artery ; consequently, the hernial sac must necessa- rily pass with the cord above this artery, before protruding from the canal of the abdominal ring. At the same time’, the inter- nal orifice of the hernia becoming larger, and the inguinal canal shortened by the approximation of its two orifices to each other, it follows, that at the period when the hernia begins to make its appearance in the groin, the epigastric artery is unavoidably situated behind the neck of the hernial sac, and is pushed from the outer to the inner side of the ring. Let us suppose a piece of string to be passed from the inside of the abdomen into the scrotum, all through the inguinal canal, and the middle of the hernia ; and that this string is pulled so as to bring the internal orifice of the hernia, which is situated beyond the point where Hie sperma- tic cord crosses the epigastric artery ; this artery will immediately be found to be car- ried from the outer to the inner side of the neck of the hernial sac. The same thing happens from the effect of the enlargement of the hernia. The removal of the epigastric ar- tery from one side of the ring to the other, (says Scarpa) isa phenomenon, which may be regarded as almost constant in the inguinal hernia. I have examined the bodies of a great number of subjects, affected with this species of hernia ; and it has been only in a very few, that I met with the epigastric artery retaining its natural situation on the outer side of the abdominal ring. In investigating the reason of this exception, I have obser- ved, in ail the individuals who presented it, a very remarkable weakness and ilaccidity of that part of the abdominal parietes, which extends from the flank to the pubes. Iti all the displaced viscera had passed through Ike aponeuroses of the transverse and internal ob- lique muscles , notin the vicinity of the ilium, as is commonly the case, but, at a little dis- iance from the pubes, giving to the upper pil- lar of the ring a curvature that is extraordi- nary, and disproportioned to the smallness of the hernia. I observed, also, that the neck of the hernial sac did not pass in an oblique direction, from the flank to the pubes, but, that it protruded from the abdomen almost in a direct line from behind forwards. In short, in these individuals, the small cul-de- sac of the peritoneum, which constitutes the prigin of the hernial sac, had not begun to be formed under the edge of th : transverse muscle, at Ihe point where flie spermatic cord runs ouhVard ; but, it hud passed through the aponeuroses of ihe internal oblioue and transverse muscles , at a little distance from th6 pubes, and within the point at which the sper- matic eord crosses the epigastric artery. The small hernial sac, having at this part come into contact with and united to the sperma- tic eord, protrudes at the external orifice of the inguinal canal, without displacing the epigastric artery from its natural situation. This species of hernia, properly speaking, isa mixture of the ventral and inguinal, it resembles the former, inasmuch as the her- nial sac pierces the aponeuroses of the transr verse and internal oblique muscles ; the lat - ter, inasmuch as it passes out at the abdomi- nal ring, conjointly with the spermatic cord.” ( Scarpa , Trade des Hernies,p. 68, fc.} Hesseibach particularly adverts to a tri- angular space to be seen on the inside of the inguinal region : the upper bound- ary of it is formed by the outer edge of the rectus muscle ; the lower by the horizontal branch of the os pubis ; and the external shortest boundary by the crural vein and epigastric artery. Now, says he, when it is considered, that this artery ascends obliquely inwards, between the inner opening of the ring, and the above triangular space, one cannot fail to know on which side of the neck of the sac the artery must lie in the two species of in- guinal, as well as the crural, hernia; for, in those hernia?, which originate in the above triangular space, this artery lies at the outer side of the neck of the hernial sac ; while, in every hernia that takes place through the in- ner opening of the inguinal canal, the same vessel is situated at the inner side of the neck of the sac. To one species of bubonocele, Hesseibach applies the epithet external ; and to the other, internal ; according to the si- tuation of the point at which they first protrude. The external inguinal hernia is much more frequent than the internal, and is said to happen oftener on the right, than the left side of the body : a circumstance, coinciding with another observation, viz. that in children, the tunica vaginalis remains longer open on the right titan the left side. The circumstance of there being two forms of inguinal hernia formerly caused considerable perplexity : surgeons knew', that the epigastric artery lay sometimes at the inner, sometimes at the outer side of the neck of the hernial sac, but knew not how to account for this variation. Hence arose the very different opinions about the proper method of dividing the ring when the her- nia was strangulated ; some authors direct- ing the incision to be made obliquely in- wards and upwards ; and others, upwards and outwards. But, as a modern writer has judiciously remarked, had they paid greater attention to the direction of the swelling, formed by the neck and body of Ihe hernial sac in the groin, and to the position of the spermatic cord, which is as inconstant as that of the epigastric artery ; and had they dissected the parts in the diseased, as w : ell as healthy, state, they could not fail soon to have suspected, that every inguinal hernia does not originate exactly at one and the same point. For the first establishment of this very important distinction, the world is indebted to Mr. A. Cooper ; and the tract, in which Hesselbach pointed out the fact in a very particular manner, I believe, is the next publication in which the subject is ex- plained. {Anal. Chir. Abhandlnng fiber den Ur sprung der Leistenbru ke, IVurxb. 180b ; and JVeuste Anal. Pathol. Untersuehangen abcr den Ursprung, fyc. der Leisten-und - Schenkelbriiche, 41 o. IVurxb. 1814, p. 18. 2(5, 28, 4'C.) According to the latter author, since each form of inguinal hernia also pre- sents characteristic appearances externally* the surgeon can have no difficulty in deter- mining the species of hernia ; which dis- crimination must he highly important in the taxis, the application of atruss, and especially the operation. The sac of the external scrotal hernia can only pass down within the expansion of the cremaster as far as this part is separate from the cord and tunica vaginalis. Hence, the testis, covered by its tunica vaginalis, lies under the lowest part of the hernial sac, while the vessels' of the spermatic cord, in a more or less separated form, are situated behind the posterior part of the sac ; viz. the spermatic veins exter- nally, and the vas deferens internally, and the artery in the middle. Should the hernia descend still further, the testis being inclu- ded as well as the sac within the tendinous expansion of the cremaster, it cannot glide out of the way, but must be pressed still fur- ther downwards by the sac, so as to con- tinue invariably under its fundus, but some- times inclined a little behind it. {Hes^clbaeh, p. 34.) And, as the same author justly ob- serves, the position of (be spermatic cord and testis, and the oblique direction of the swell- ing in the external species, are the two strongest characters by which every case of inguinal hernia may be discriminated. Although the spermatic cord commonly lies behind, or under, the hernial sac, there are cases in which t lie vas deferens is found on the cuter side of it, while the rest of the spermatic cord lies, as it usually does, on the inner side, or rather under it. (Cooper.) Le Dran, Schmucker, and Blizard, found the whole cord situated in front of the sac. Sometimes the vas deferens runs on the front and inner part, and the rest of the cord on the back and external part of the swelling. ( Camper , Hey.) The cord has been known to be before, and the. vas deferens behind, the sac. (Camper, A. Cooper.) Upon this part of the subject, the reader may deem the following passage interesting. While the hernia is of moderate size, (says Scarpa) the surrounding cellular substance is not very greatly compressed, and no change is observed in the situation of the spermatic vessels. The artery and veins of this nanSe always form, with tiie vas defer- ens, one single cord, which is intimately ad- herent to the posterior surface of the hernial sac. But, in proportion as the tumour in- creases in size, the cellular substance, which immediately surrounds it, and unites it to the spermatic cord, is more and more distended and compressed. At length, at a certain pe- riod, the distention is carried to such a pitch, that the spermatic vessels are separated from one another, and change their position with respect to the hernial sac. This kind of gradual unravelling of the spermatic cord is quite similar to that, which w ould he pro- duced by pulling the surrounding cellular substance in two opposite directions. Such is the reason, why in scrotal hernia of large size, the spermatic artery, the vas deferens, and the spermatic veins are found separated upon the posterior surface of the sac. All these vessels, instead of being conjoined in one cord, are divided by interspaces, which are sometimes very considerable. Ordina- rily, the vas deferens is less separated from the spermatic artery, than from the vein of this name. In some subjects, Camper has seen it situated on one side of the sac, and the arlery and veins on the other. (leones Herniarym, Tab. 5, L. O. Tab. 8. 1,2.) The. displacement and splitting of the spermatic cord take place equally in adults and in chil- dren affected with 1 urge scrotal hernia?. (Camper, loco cil.) In general, towards the up per part and neck of the hernia, the vessels are not much separated ; but as they proceed downwards, they diverge more and more. Sometimes, when the hernia is very old and bulky, they are no longer found at the pos- terior part, but rather at the sides, and even on the front surface of the sac ; tiiey show themselves thupugh the cremaster muscle, which covers them, and form a sort of vas- cular train, which arrests the hand of the operator at the moment when he is about to open the hernial sac. Le Dran relates, that in operating upon a large scrotal hernia, he found the spermatic cord on the anterior surface of the hernial sac. ( Operations de Cftir.p. 127.) This fact has been the cause of numerous conjectures, and has appeared altogether inconceivable to such surgeons as have not been acquainted with the changes, to which the spermatic cord is ex- posed, in cases of large^scrotal hernia’. (Lassus could not (Med. Opemt. T. 1, p. 152.) conceive the possibility of the occui- rence.)" The observation of Le Dran is not the less true and exact ; it exemplifies a vety important fact, of which it is easy to give a true explanation when the state of the sper- matic cord in ordinary inguinal hernia’, and in those which have obtained a considerable, size, has bfeen comparatively examined. In the first, the 'spermatic cord quite entire is always found situated on the posterior surface of the hernial sac ; but, in the second, the spermatic vessels are so separated from one another, that they sometimes extend over the sides and even the forepart of the hernial sac.” ( Scarpa , Trait ; des Herhie.Si p. (51. <$-e.) The hernial sac is commonly described as an elongation of peritonauim. When more minutely examined, however, it is found, in cases of inguinal hernia, to consist of the portion of peritoh;euin : pushed out with the 20 Hernia viscera ; of a layer 6f cellular substance on the outside of this, which becomes more or less thickened by the pressure of the rupture in different cases} of a fascia, sent off from the tendon of the external oblique muscle ; and of the cremaster muscle, which latter parts form the exterior cover- which consisting of several layers, often ■ ads the operator to fancy that he has open- • cavity of the sac, when, in reality, he bus not. It is observed by Professor Scarpa, that iho cremaster muscle, in cases of old large rrotal hernia;, acquires a thickness, which •> really surprising. Its fibres, which are naturally very thin, become from four to mx times more considerable. Being spread over the neck and body of the hernial sac, they sometimes present a remarkable con- rosience, and a yellowish colour. Such al- teration, however, does not prevent the muscular texture from being discovered, ad Haller was not mistaken about it. {Op use. Palkolo g. p. 317.) Pathology fur- nishes us with several examples of similar changes of organization. In certain cases, muscular coat of,tlie bladder, that of the ; roach and intestines, and even the ex- edingly delicate fleshy fibres of the liga- ; its of the colon, are found to have be- me yellow, and much thickened. “ In old scrotal hernia? (says Scarpa) it is • ! unusual to find an intimate adhesion of fibres of the cremaster muscle to the 5 jges of the abdominal ring. This may de- ad on the pressure, which the contents ; the hernia makes on those edges, and per- ; ps it may also depend on the union of , r ^ remaster muscle with the prolongation of me aponeurosis of the fascia lata, which . i. ouimued from the margins of the ring to .coin and scrotum. Howsoever it may bi , certain it is, that in old large scrotal . - map there is much difficulty in introdu- cing a probe between the fleshy fibres of cremaster and the margin of the abdomi- .1 ring ; and that, on the contrary, in recent herniae, a probe passes as easily between the edges of the ring and the cremaster, as be- iveen this muscle and the hernial sac. “ Few authors (according to Scarpa) have mken of tire sheath, formed by the cre- ter muscle, in which are enclosed the - .ml sac, the spermatic cord, and the tu- ; ■> vaginalis of the testicle. Sharp (in Uical Inquiry ) and Monro, the father, and Chirurg. Works , p. 5£>3.) were fhu first to dwell upon this important patho- eal point. Monro had seen the cremas- t«. prouscle covering the hernial sac } but he not believe, that the same thing occur- ln all individuals affected with inguinal ■ : a. In this respect he was mistaken } this disposition of the cremaster muscle j-.- - of the essential characters of the dis- Petit has not omitted to describe the bn us which exist between the creraas- ■ cl the hernial sac. (C Euvres Post hum. ' > , p. 288.) On this subject, he even re- , an interesting fact, from which it re- that in verSarn ^ases ; this muscle may by its contractions alone cause a reduction of the hernia. Guntz explains, with tolera- ble perspicuity, how the cremaster and its aponeurosis form one of the coverings of the inguinal and scrotal hernia. (Libellus de Ilerniis , p. 50.) Morgagni once saw its fleshy fibres extended over the hernial sac } ( Dc sed. et cans. morb. epist. 34, art. 9; cpist. 31, art. 15.) and Neubaver positively assures us, that he made the same remark upon the dead body of a man affected with an emtero-epiplocele. ( Dissert . de Epiplo- oscheocele.) After these facts, so positively and accurately observed, I cannot compre- hend (says Scarpa) how in our time Pott, .Richter, and several other authors, should have passed over in silence, or only men- tioned vaguely, this point, so important in the history of the inguinal and scrotal her- nia.” ( Scarpa , Traiti des Hernics , p. 48, 50.) When surgeons speak of a hernial sac be- ing usually thicker and stronger, in propor- tion to the magnitude and deration of the. hernia, their language is not at all correct ; for in fact, the peritoneal investment of the hernia is seldom, or never, thus alter- ed. I can declare (says Scarpa) after nu- merous observations, that in the majority of cases, the hernial sac, strictly so called, is not perceptibly thickened, and that in gene- ral it does not differ from other parts of the peritonaeum, however large and old the scrotal hernia may be. ( Trait6 des Her nies, p. 53.) In a very enormous hernia, the pressure of the contents is so great, that instead of thickening the sac, it renders it thinner, and even makes it ulcerate. The protruded vis- cera have been met with immediately be- neath the integuments, when the sac has been burst by a blow. ( Cooper ; J. L. Petit.) The outer surface of the peritonaeal part of the hernial sac, is always most closely ad- herent to the other more external covering by means of cellular substance. This con- nexion is formed so soon, after the first occurrence of a hernia, that any hopes of returning a hernial sac into the abdomen are now generally considered as chimerical. There must, however, be a certain space of time, before adhesions form, though it is, no doubt, exceedingly short. Upon this point, Scarpa does not adopt the opinion commonly received. There is no doubt, he observes, that in re- cent and small inguinal hernias, the intes- tine, strangulated by the neck of the hernial sac, has been known, in more instances than one, to have been reduced by the taxis, and carried with it the whole of the sac into the abdomen. Observations, not less authentic, inform us, that after the operation for hernia, when the viscera could not be reduced on acbount of their adhesions to the sac, they have been seen, notwithstanding such ad hesions, to get nearer to the ring daily, and at length, spontaneously to return into the belly together with the hernial sac. Louis, he thinks, was wrong in denying the possi- bility of these facts. (sJead. Ptoyale de Chir. T. 11 : p. 4SC».) HKKNIA. Scarpk argues, that i: under certain cir- cumstances, the cellular substance will bear, without laceration, a considerable elonga- tion, and afterward shrink again. Thus we often see a viscus, which has suffered a con- siderable displacement, return spontaneous- ly into its natural situation. In the ingui- nal hernia, the spermatic cord is elongated, and descends farther, than in the natural state. No laceration of the cellular sub- stance, however, is then occasioned ; for, if the hernia be kept reduced, the spermatic cord becomes shorter, daily retracts, and at last has only the same length, which it had previously to the disease. When a sarco- cele becomes large and heavy, the portion of the spermatic cord naturally situated within the belly, is by degrees drawn out into the scrotum ; but, after the tumour is extirpated, this portion ascends again, and of itself returns into its original situation. “ The same thing happens after the ope- ration for the strangulated inguinal hernia. All practitioners have noticed, that the hernial sac retracts and reascends progres- sively towards the ring. This alone would prove, that the cellular substance, which surrounds the spermatic cord, and unites it to the hernial sac, is highly endued with the property of yielding, and afterward re- turning to its original state. Can the same property be refused to the cellular sub- stance, which unites the sac to the cremas- ter muscle and other surrounding parts ? “ While the inguinal hernia is recent, and not of much size, the cellular substance in question, possesses all its elasticity, and lienee, the hernial sac and the spermatic cord, may easily ascend towards the abdo- minal ring. I have had occasion (says Scarpa) to make this observation upon the dead body of a man, who had an incipent inguinal hernia. The small hernial sac was capable of being pushed back into the ring with the utmost facility ; and in carefully examining the parts, both within and with- out the belly, it appeared to me, that the cellular substance, which united the sac to the spermatic cord and cremaster muscle, was disposed to yield equally from without inwards, and in the direction precisely op- posite ; that is to say, it made an equal re- sistance to the protrusion and the reduction of the hernial sac. Monteggia has seen a case exactly similar : although, according to his own expressions, ( Inslituz . Chirurg. T. 3, ses. 2, p. 249,) the hernial sac was not very small, it adhered very loosely to the surrounding parts, and it admitted of being entirely reduced into the abdomen with great facility.” In large old scrotal hernias, Scarpa allows, that such reduction is quite impracticable : c; Iu these, the cellular substance, which unites the sac to the spermatic cord, and cremaster muscle, has acquired such a den- sity, that it does not oppose less resistance to the further enlargement of the hernia, than to the efforts of the surgeon, who en- deavours to effect its reduction.” ( Scarpa , Traiti das Hernias, p. -57. <*c.) Though Scarpa thus reasons about the elasticity of the cellular substance, as forming the con - nexion between the sac and surrounding parts, many surgeons would refer the con- nexion to the adhesive inflammation, and explain the diminution and shrinking of parts, after the distention and weight are removed, not by the elasticity of the cellu- lar substance in particular, but by thesamo property inherent generally in the elonga- ted parts, which elasticity, and the action of the absorbents together, produce the al- teration in question We shall conclude this anatomical account of the inguinal hernia, with the following explanation of the parts as they appear on dissection : “ the removal of the integu- ments exposes the exterior investment of the hernial tumour, continuous with the margins of the ring, and formed of tendi- nous fibres from the aponeurosis, the cre- master muscle, &c. This is connected by cellular substance with the. proper hernial sac, formed of the peritonamm. This pro- duction of the peritonaeum passes within the ring of the external oblique, and then goes upwards and outwards. Behind ami above the ring, the inferior margin of the obliquus internus and transversalis crosses the neck of the sac When these muscles are reflected towards the linea alba, the fascia, ascending from Poupart’s ligament, and forming the upper opening of the ring, is exposed, and the epigastric artery is dis- covered emerging from the inner side of the neck of the hernial sac, ( Campari leones, Tab. X. F. M.) which, at this precise point, becomes continuous with the peritonaeum, lining the abdomen. The removal of the hernial sac will disclose the course of the spermatic cord in its descent towards the testicle ; and when this is also elevated, the first part of the course of the epigastric ar- tery, and its origin from the iliac trunk, are exposed.” ( Lawrence on Hernia , p. 182 Edit. 3.) In females, the round ligament of the ute- rus bears the same relation to the tumour, as the spermatic cord in males. In the former subjects, bubonoceles are uncommon. Mr. Lawrence had a very rare instance pointed out to him, in which a bubonocele in a female was situated on the inner side of the epigastric artery. A still rarer case was examined by Hesselbach : it was not only an example of internal bubonocele in a woman, but of one in which the epigastric artery arose from the obturatrix artery an inch from the origin of this latter vessel from the inner side of the external iliac : the obturatrix first passed an inch obliquelv downwards and inwards over the crural vein, and immediately afterward, on the ho- rizontal ramus of the pubes, made a sudden turn backward and downward to the obtu- rator foramen ; and at this bend arose the epigastric artery, which ran transversely in- ward along the horizontal ramus of the pubes, behind the neck of the hernial sac, at the inner side of which it ascended to the rectus muscle, accompanied by the llga- HERNIA. mentous remains of the umbilical arteries, which were close behind it. ( Uebcr den Ursprung, fyc. der Ltislen und Schenkel- brtiche, p. 17.) MARKS OF DISCRIMINATION BETWEEN OTHER DISEASES AND INGUINAL HERNIA:. The disorders, in which a mistake may possibly be made, are Cirsocele, Bubo , Hy- drocele, and Hernia Humoralis, or Inflamed Testicle. For an account of the manner of distin- guishing the first complaint from a bubono- cele, see Cirsocelc. u The circumscribed incompressible hard- ness, the situation of the tumour, and its being free from all connexion with the spermatic process, will sufficiently point out a bubo, at least while it is in a recent state; arid when it is in any degree suppurated, he must have a very small share of the Indus eruditus , who cannot feel the difference be- tween matter, and either a piece of intes- tine, or omentum. “ The perfect equality of the whole tu- mour, the freedom and smallness of the spermatic process above it, the power of feeling the spermatic vessels and the vas de- ferens in that process, its being void of pain upon being handled, the fluctuation of the water, the gradual formation of the swelling, its having begun below and proceeded up- wards, its not being affected by any pos- ture or action of the patient, nor increased by his coughing or sneezing, together with the absolute impossibility of feeling the tes- ticle at the bottom of the scrotum, will al- ways, to an intelligent person, prove the disease to be a hydrocele.” Mr. Fott, how- ever, allows that there are some exceptions, in which the testicle cannot be felt at the bottom of the scrotum in cases of hernia. “In recent bubonoceles, while the hernial sac is thin, has not been long, or very much distended, and the scrotum still preserves a regularity of figure, the testicle may almost always be easily felt at (lie inferior and pos- terior part of the tumour. But in old rup- tures, which have been long down, in which the quantity of contents is large, the sac considerably thickened, and the scro- tum of an irregular figure, the testicle fre- quently cannot be felt, neither is it in gene- ral easily felt in the congenital hernia for obvious reasons.” (Pott.) “ In the hernia humoralis , the pain in the testicle, its enlargement, the hardened state of the epidydimis, and the exemption of the spermatic cord from all unnatural fulness, are such marks as cannot easily be mistaken ; not to mention the generally preceding go- norrhoea. But, if any doubt still remains of the true nature of the disease, the progress of it from above downward, its different state arid size in different postures, particu- larly lying and standing, together with its descent and ascent, will, if duly attended to, put it out of all doubt, that the tumour is a true hernia (Poll.) When an inguinal hernia docs not de- scend through the abdominal ring, but only into the canal for the spermatic cord, it is co- vered by the aponeurosis of the external oblique muscle, and the swelling is small and undefined. Now and then, the testicle does not de- scend into the scrotum till a late period, and its first appearance at the ring, in order to get into its natural situation, may be mistaken for a hernia, unless the surgeon pay atlen- tion to the absence of the testicle from the scrotum, and the peculiar sensation occa- sioned by pressing the swelling. POINTS OF DIFFERENCE BETWEEN THE EX- TERNAL AND INTERNAL INGUINAL HER- NIA, &ic. According to Hesselbach, the characteris- tic marks of the external bubonocele and scrotal hernia are ; 1st. The direction of the tumour in the groin. 2dly. The fleshy fibres of the cremaster. 3dly. The position of the spermatic cord and testis. 4thly. The situation of the epigastric artery. 5th ly. The origin of the hernia itself. 6th ly. A preternatural shape of the body of the her- nial sac. 1. The neck of the hernial sac, distended by the protruded viscera, raises up the front side of the inguinal canal, and superincum- bent integuments, into an oblong swelling, which extends obliquely inwards and down- wards towards (he abdominal ring, and ter- minates in the tumour, formed by the body of the hernial sac. From its origin it be- comes gradually more prominent and broad, and the greater the quantity of viscera pro- truded, and the larger the body of the sac, the more manifest is this oblique swelling, particularly when the neck of the hernia is of its natural length. In slrangulated cases, the direction of the tumour is still more striking, every part of the hernial sac being then considerably distended. When the in- guinal canal, and of course the neck of the liernial sac are shortened, the swelling under- goes a proportional diminution in its length ; and then its resemblance to the tumour at- tending an internal inguinal hernia, where the opening through which the parls pass, is long and slanting, is so great, that the cases can only be discriminated by one circum- stance, viz. the situation of the spermatic cord, and even this criterion is of course wanting in females. ( Hesselbach , p. 57, 58,) Hesselbach clearly explains, that he obli- quity of the swelling is seated in the neck of the hernial sac. He observes, that when an internal bubonocele in a female subject passes into the labium, the descent takes place in a very sloping direction inwards, and therefore, may at first be supposed to be an external case. But, on further examina- tion, the oblique swelling will be found to occupy Ihe body of the hernial sac, and to reach upwards and outwards from the la- bium to the abdominal ring. Now this her- nia cannot bo mistaken for an external bu- bonoceie, the course of which from the ring is obliquely upwards and outwards. .HERNIA, llcsselbach reminds us, that an internal, inguinal, or scrotal hernia may be conjoined with an external incomplete bubonocele ; a kind of case easily made out with a little at- tention ; for the place of division between the two sacs is indicated by a more or less deep groove, ihe nature of the disease will also be still dearer, if one ot the tumours admit of reduction. A specimen of such a double hernia is to be seen in the museum at Wurzburg. It is further noticed by Hesselbach, that, when the situations of the external and in- ternal hernia) are compared, the first of these swellings will be found to be rather further than the other, from the symphysis of the pubes : a difference ascribed to the effect of the internal oblique muscle, the lower fibres of which, attached to the horizontal ramus of the pubes, run in a curved direction trans- versely over the anterior and inner part ot the neck of the hernial sac, and are applied so closely to it, that it cannot approach quite so much towards the symphysis of the pubes as the neck of the internal bubonocele does. The muscular fibres in question are situated directly behind the inner pillar of the abdo- minal ring. 2. Most of the fibres of the cremaster lie on the back of the neck of the sac, blit others are also scattered over its external and internal sides: Some fibres may also be perceived on its forepart, which are re- markable, because they run in a transverse curved direction with their convexity down- wards, and two fasciculi of which descend below the abdominal ring. These are the fibres of the cremaster, which proceed within the ring transversely upwards over the sper- matic cord, and are pushed out of that opening by ihe hernial sac. These arched fleshy fibres are not always, though gene- rally, perceptible ; and, when they are pre- sent on the forepart of the hernial sac, Hes- selbach accounts them a sure criterion of an external scrotal hernia ; but, he has not yet ascertained, whether they are visible, while the rupture is confined to the groin. 3. The situation of the spermatic cord and testis in the external inguinal hernia, and, 4. That of the epigastric artery, and its displacement inwards by the neck of the sac, have been sufficiently explained. 5. With respect to the mode, in which the hernia originates, the disease often takes place suddenly, without any exciting cause being observed, capable of accounting for the effect. Here, says Hesselbach, the pre- disposing cause must have been great ; for instance, the communication between the cavity of the peritonaeum and that of the tunica vaginalis has remained a long while unclosed ; and, when a hernia of this de- scription is examined, the other marks of an external inguinal hernia are associated with the sudden formation of the disease. In this quick manner, the congenital hernia, which is one of the external cases, frequently .arises. The internal inguinal hernia is also observed mostly to take place very sud- denly, yet only after violent occasional causes. 6. A preternatural form of the body of the hernial sac, Hesselbach remarks, is particu- larly sealed in the shettth of the spermatic cord, and can never happen in the internal scrotal hernia; for, it is only in- external cases, that the above sheath is ever convert- ed into the hernial sac. Hesselbach here refers to the -partial contraction, often no- ticed at the lower part of the above sheath in cases of congenital hernia ; a circum- stance, which is always discovered previ- ously to the business of dividing the ring. In adults, an external inguinal, or scrotal hernia, on the right side, contains some of the ileum, and, when the swelling is large, it may include the ccecum, and some- times a piece of omentum. In one child, ten weeks old, and in another still younger, the appendix vermiformis was protruded and connected by a natural band to the posterior side of the peritonaeum. When, in these ruptures of the right side, the ccecum, or, in those of the left, the colon are met with, closely adherent to the hinder side of the hernial sac, the adhesion is not to be looked upon as the effect of disease, since it is the perfectly natural connexion of those bowels with the peritonaeum. On the left side, the parts most commonly protruded are the colon and omentum. With regard to the internal inguinal hernia, the place of its first protrusion has , been already described. The protruded perito- naeum and viscera, accordingto Hesselbach’s account, pass from behind straight forwards , between the fibres of what he names the in- ternal inguinal ligament, and the fleshy fibres of the internal oblique muscle : they then pass, at the inner side of the spermatic cord, out of the abdominal ring, where the hernia presents a circular globular swelling, sud- denly formed in consequence of some violent effort. The neck of the hernial sac is very short ; shorter than it can ever be in an ex- ternal inguinal hernia, and, when the tumour is of Uthe above shape, the passage through which it passes is annular, narrower. in some instances than others, and its margin is ten- dinous. From the few cases, which Hessel- bach has seen of this form of the disease, he is led to conjecture, that the hernial sac is rarely so large as in the external inguinal hernia. (jP. 41.) The earlier dissections made by Hesselbach, led him to suppose, that, in the internal inguinal hernia, the opening, through which the protrusion hap- pens, is always annular, and the swelling in front ot the ring globular ; b it subsequent cases, which he has met with, have informed him, that the opening is frequently sloping and longisb, in which circumstance, the re- semblance of the tumour to that of the ex- ternal bubonocele with a shortened neck, is such, that the only mark of distinction be- tween the two cases is the position of the spermatic cord. In females, even this crite- rion is of course deficient. ( Hesselbach , p. 57.) Though individuals of almost every age are subject to internal bubonoceles, they 24 HERNIA. arc much less common than external cases. According to Hesselbach, they may be known by the following characters. 1. The swelling, formed by the body of the hernial sac, immediately in front of the abdominal ring. 2. The situation of the spermatic cord. 3. That of the epigastric artery. 1. The neck of the hernial sac, besides being very short, does not, like that of an external inguinal hernia, take an oblique di- rection, but advances straight from behind forwards through the abdominal ring, and as the body of the sac lies directly over the neck, none of the swelling, formed by the distention of the latter part, can bo felt. Nor does any other tumour, produced by the body a hernial sac, ever cause a circular spherical swelling directly before the abdo- minal ring. The situation of the neck of this kind of hernia must already apprise us, that the internal bubonocele is nearer, than the external, to the symphysis of the pubes. In women, the shape of the tumour is the only character, by which the case can be distin- guished. (Hesselbach, p. 43.) 2. After what has been already stated, re- specting the situation of the spermatic cord in the internal inguinal hernia, I shall merely notice one or two observations of Hesselbach. The cord lies either upon the outer side, or outer half of the forepart of the upper portion of the hernial sac, the blood-vessels forwards, and the vas defer- ens backwards. When the sac is adherent to the whole length of the cord, the testis is not situated under the fundus of the sac, as in the external scrotal hernia, but either at the forepart or outer side of the body of the sac. The hernial sac, as far as the abdominal ring, is excluded from the common perito- naea! covering of the spermatic cord, but at this opening, it descends between the cord and the internal thin part of the sheath of the cremaster, which, how r ever, is somewhat stronger towards the front and outer side of the hernia, over which part alone the fleshy fibres of the cremaster are spread. (P. 44.) 3. The epigastric artery always ascends ob- liquely Inwards at the outer side of the neck of the hernial sac. Hesselbach has never seen but one case of internal bubonocele, in which there was a deviation from this rule. The example has been already mentioned, and was one in the epigastric artery, arose from the obturatrix about an inch from the origin of this last vessel. The viscera, usually contained in an internal inguinal, or scrotal hernia, on the right side, are the lower part of the small intestines, and sometimes omentum ; on the left, a paid of the small intestines, frequently omentum, and when the tumour is large, the colon may also protrude. A protrusion of the bladder may accompany the disease, but that organ is of course always excluded from the cavity of the hernial sac. When the re- mains of the umbilical cord are situated more outward than usual, and lie over the centre of the space, at which the protrusion happens, an internal bubonocele may he double, the prolapsus happening on each side of that ligamentous substance, which isf itself also pushed outwards. In consequence, of the accidental presence of some very strong tendinous fibres at the centre of the fascia, called by Hesselbach the internal inguinal ligament, there may also he two distinct protrusions, with separate hernial sacs. (P. 46.) When the surgeon, by a due consideration of the foregoing circumstances, has formed a judgment respecting the nature of the her- nia, he will be better qualified to regulate the treatment of the case. Thus, in the ex- ternal inguinal hernia, he will know, that the pressure, employed for the reduction of the bowels, should be made in the direction of the neck of the hernial sac, viz. obliquely upwards and outwards, towards the anterior superior spinous process of the ilium; but that, when the neck of the same kind of hernia is very short, and the poste- rior side of the inguinal canal has been re- moved, the pressure should he made nearly in a straight line from before backwards. For what Hesselbach terms the long-necked external inguinal hernia, the pad of a truss should be so constructed, as not merely to press upon the abdominal ring, but also upon the neck of the sac and the inner opening of the inguinal canal. But, when the neck of the hernia is very short, the pad should be nearly of the same form, as that required for an internal inguinal hernia. ( Hesselbach , p. 38; and Brunninghausen, Ge- meinnutziger Unlerricht fiber die Bruche, fyc. Wurzb. 1811.) In attempting the reduction of an internal inguinal hernia, the pressure should be directed nearly straight back- wards ; and the pad of the truss should only act upon the abdominal ring. (Hesselbach, p. 46.) THE OPERATION FOR STRANGULATED INGUI- NAL HERNIA, OR BUBONOCELE Consists in dividing the integuments ; dis- secting down to the sac, and opening it; removing the stricture ; and replacing the protruded viscera. The external incision should begin an inch above the external angle of the ring, and extend over the middle of the tumour to its lower part. The advantage of begin- ning the wound so high, is to obtain con- venient room for the incision of the stric- ture. By this first cut, the external pudic branch of the femoral artery may be divi- ded ; it crosses the hernial sac near the abdo- minal ring, and sometimes bleeds so freely, as to require to be immediately tied. In general, however, a ligature is unneces- sary. When this incision is carried low down, the caution, given by Camper, should always he remembered, viz. that there is a possibili- ty of dividing the spermatic vessels, should they happen to be situated, as they some- times are, in front of the hernia. And, in order to avoid such an accident, which is particularly apt to occur in cases of internal inguinal, or scrotal hernia, the incision .'HERNIA. through the skin should be made obliquely downwards and inwards. ( Hesselbach , jj. • 46 .) The division of the integuments brings into view the fascia, which is sent off from the tendon of the external oblique muscle, and covers the hernial sac. The layers of tendinous fibres, cellular substance, &.c. intervening between the skin and sac, should be carefully divided, one after another, with the knife and dissecting forceps, the edge of the former instrument be- ing turned horizontally, lest the incisions be carried too deeply at once, and the viscera contained in the sac wounded. .After making a small opening through a part of the fascia covering the sac, some practitioners introduce a director, and di- vide this fascia upward and downward as far as the tumour extends. The same man- ner they next pursue with regard to the cre- master muscle. Thus the sac .becomes completely exposed. When this method is followed, Mr. A. Coope; advises the inci- sions not to be carried upward, nearer than ona ; nch,to the abdominal ring, for reasons which will be presently explained. However, it may be rationally doubted, whether there is any good in these formal and successive divisions of the whole length oftke coverings of the sac ; and it is certain, that they protract the operation very much ; for the manner in which the sac adheres to the outer investment of it, prevents the lat- ter from being raised and cut without trou- ble rnd delay. As the grand object, after the skin has been divided, is to make a small opening into the sac, sufficient for the intro- duction of a director, dissecting down at one particular place answers every purpose, and enables us, in the end, to lay open the whole of the sac and its coverings in the shortest time. Let the operator only take care to raise the successive layers of fibres with the forceps, and divide the apex of each eleva- ted portion with the knife held horizontally. As there is commonly a quantity of fluid in the sac, and it gravitates to the lower part, to which place the intestine seldom quite descends ; this is certainly the safest situa- tion for making the first opening into the sac. The operator, however, should not rely upon the presence of such fluid, and cut too boldly , for sometimes it is absent, and the viscera may be in immediate con- tact with, nay, adherent to, the inner sur- face of the sac. The circular arrangement of the vessels of a piece of intestine, and its smooth polished surface, sufficiently distinguish it from the hernial sac, which has a rough cellular sur- face, and is always connected with the sur- rounding parts, although these adhesions, in a very recent case, may be but slight. ( Lawrence on Ruptures , p. 214, Edit. 3.) I have mentioned, that Mr. A. Cooper only advises cutting the fascia, and other coverings of the sac, under the skin, to within an inch of the abdominal ring; and, of course, he also recommends limiting the division of the sac itself to the same ex- tent. His reasons for this practice, are to Vor . I k 1 avoid making the closure of the wound more difficult, and to lessen the danger of peritonaial inflammation. Having laid open the hernial sac with a probe-pointed bistoury, guided by a direc- tor, or the fore-finger introduced into the opening, made at the lower part of the sac, the next desideratum is to divide the stric- ture, unless the viscera admit of being easily reduced, without such an incision being made as occasionally happens. From the anatomical account, which has been given of the bubonocele, it appears, that the stricture may either be situated at the abdominal ring, and be formed by the margins of this opening, or else at the inner aperture of the canal, about one inch and a half, in a direction upward and outward, from the outer opening in the tendon of the external oblique muscle. This latter stran- gulation is caused by the semicircular edge of the transversalis muscle and its tendon, which pass over the neck of the hernial sa(T, and by a fascia, arising from Poupart’s liga- ment, the semicircular border of which passes under this part of the sac. 'file common, and probably the best prac- tice is to divide the hernia! sac, together with the stricture. When this is situated at the abdominal ring, the surgeon is to intro- duce the end of a director a little way into the neck of the sac, within the aperture in the tendon, and with a probe-pointed bis- toury, guided on the latter instrument, he is to cut the stricture upward and outward, or else directly upward ; a manner, which Mr. A. Cooper recommends, because it is appli- cable to all cases, even the less frequent ones, in which the hernia protrudes at the. inner side of the epigastric artery; and, in all common instances, vre know, that this vessel runs upward round the inner side of the neck of the sac ; a course prohibiting the division of the stricture upward and in- ward. fn the external inguinal hernia, the me- thod of cutting the stricture upward and outward is perfectly safe ; but when the case is what Hesselbach calls internal, and the viscera descend on the inner side of the epigastric artery; it is a plan which would endanger the latter vessel, and ought never to be adopted, notwithstanding any state- ment made in its favour by Rudlorfier. Ab- handlung iiber die einfachsle und sichersle opcrations-Methodc eingesperrier Leislcn-und- Schenkelbriiche. Wien. 1808.) Tn this work the erroneous plan of cutting the ring in- wards is inculcated, both in the external and internal inguinal rapture. The author, how- ever, seems to have performed many opera- tions in this manner, without any accident from hemorrhage; a piece of good fortune, which Professor Langenbeck ascribes to the circumstance of the knife having always been applied, as iludtorffer directs, to the middle of the inner pillar of the ring, and to the cut having been very limited. Langen- beck is of opinion, that, if the knife bad been applied a little lower, and the incision car- ried to any extent, the epigastric artery, in HERNIA. ordinary oases, would not have escaped injury. !\Ir. A. Cooper’s rule of always cutting in one direction, viz. upward, which I believe was first advised by Autenrieth, D/s- serf. Moment, circa Hernia tom. prcccipue circa evitandam art. epigastr. loesionem , , Tub. 1799) is perhaps a very good one, because it is at least easy for the memory, and will answer very well even when it is not in the power of the surgeon to pronounce positively whe- ther the case is a short-necked external hu- bonocele, or an internal one with an oblong oval fissure, cases having a great external resemblance, especially in women, in whom there is not the spermatic cord as a crite- rion ; for, after all, this part, when present, is the surest guide, and that on which De- sault founded his perfectly safe advice, viz. when the cord is at the posterior or inner side of the neck of the hernial sack, to divide the ring upwards and outwards, but inwards and upwards when it lay at the outer or on the forepart of the sac. ( CEuvres Chir. de Bichat , T. 2.) At least, this advice is sub- ject but to one exception, which is the very rare one of the epigastric running round the inner side of the neck of the sac in an inter- nal bubonocele ; a possibility which has been already explained, and which leads Hesselbach particularly to recommend the division of the ring in every internal ingui- nal hernia, to be made straight upwards. ( P . 47.) Indeed, the long-necked external bubonocele is the only case in which he thinks the latter plan should give way to that of cutting upwards and outwards. The safety and propriety of the method of always cutting upward, are strikingly illus- trated by what Scarpa observes : he states, that the right direction of the incision of the ring is directly upwards, parallel to the lineaalba. “ I have (says lie) operated in the way which 1 recommend upon several dead subjects, who had either external or internal inguinal hernia?, directing my inci- sion in the course of a line drawn from the upper part of the ring parallel to the linea alba; in all, I constantly left the epigastric artery untouched, even when I extended the cut about an inch above the inguinal ring.” ( Scarpa , Traiti Pratique des Ilernies, p. 111.) Only one objection, as far as I know, has been made to this plan, and it is founded on the alleged impossibility of introducing the knife, so as to cut straight upwards, when the neck of the hernial sac is long, because then the posterior side of the inguinal canal is in the way. ( Hesselbach , p. 40.) No more of the parts forming the stricture, should be cut than is just sufficient for allowing the protruded viscera to be reduced without bruising or otherwise hurting them ; and I consider the middle of the upper margin of the ring the safest place for making the ne- cessary incision. Mr. A. Cooper, in his valuable work on the Inguinal Hernia, advises a mode of di- viding the stricture, considerably different from the usual method. He directs the fin- ger of the operator to be introduced into the sac, (which, in his plan, we know is left un- divided for the space of one ipch below Ihc ring.) When the stricture is felt, a probe- pointed bistoury is to be conveyed over the front of the sac into the ring (between the two parts.) and the latter only is then 1o be divided, in the direction upward, opposite the middle of the neck of the sack, and to an extent just sufficient to allow the protru- ded parts to be returned into the abdomen without their being hurt. The two chief advantages which Mr. A. Cooper imputes to this method, are, that the danger of perito- neal inflammation will be less, and that the epigastric artery, if wounded, would not bleed into the abdomen. 1 am of opinion, that Mr. Lawrence’s remarks, concerning this proposal, are judicious : “ An accurate comparative trial of both methods would be necessary, in order to determine the weight of the first reason. The second circum- stance cannot be a matter of any importance, if we cut in such a direction as to avoid the risk of wounding the artery. Many circum- stances present themselves as objections to this proposal. The manoeuvre itself, although perhaps easy to the experienced hand of such an able anatomist as Mr. C., would, I am convinced, be found highly difficult, if not impracticable, by the generality of sur- geons. This difficulty arises from the firm manner in which the sac and surrounding parts are connected, we might almost say consolidated, together. The experience of of Richter (Traitd des Hernies, p. 118) shows, that this objection is founded in reality. He once tried to divide the ring, without cut- ting the sac, but lie found it impracticable. If the stricture is so tight as to prevent the introduction of the finger, there must be great danger of wounding the protruded parts. The practice would still be not adviseable, even if it could be rendered as easy as the common method of operating. Mr. C. leaves an inch of the sac, below the ring, undivided ; thus a bag remains ready to receive any future protrusion, and the chance of a radical cure is diminished. It would be better to follow the advice of Richter, and scarify the neck of the sac, in order to promore an adhesion of its side?. He has found this practice so successful in accomplishing a radical cure, that he ad- vises (p. 191.) its employment in every operation for strangulated hernia.” (See Lawrence on Ruptures, p. 321, Edit. 3.) If the stricture should be at the inner opening of the canal for the spermatic cord, Mr. A. Cooper advises the operator to intro- duce his finger into the sac, as far as the stricture, and then to insinuate a probe- pointed bistoury, with the flat part of its blade turned towards the finger, between the front of the sac and the abdominal ring, till it arrives under the stricture, formed by the lower edge of the transversalis and obli- quus interims. Then the edge of the instru- ment is to be turned forward, and the stric- ture cut in the direction upward. This plan of not cutting the neck of the sac, is liable to all the objections stated by Mr. Law- rence, in regard to the case in which the HE KM 27 strangulation takes place at the abdominal ring. Mr. A. Cooper’s bistoury is a very proper one for dividing the stricture, as it only has a cutting edge to a certain distance from the point. Perhaps, on the whole, we may infer, that it is botli most easy and ad- vantageous to divide the neck of the sac, together witli the stricture, whether this be situated at the ring, or more inward. The method of cutting the stricture from without inwards l consider objectionable, on the ground of the risk of wounding the bowels tu this mode, being greater, than that of any accident wounding the epigastric arte- ry, when it arises in an unusual manner, and deviates from its regular course ; a re- flection, which has made Dr. Hesselbach, junior, an advocate for the practice. (See Sicherste Art dts Bruckschnilles, 4 to. Bam- berg. 1819.) Room being made for the reduction of the protruded parts into the abdomen, by the division of the stricture, they are imme- diately to be returned, if sound, and free from adhesions. This object is considerably facilitated by bending the thigh. The intes- tines are to be reduced before the omentum, but when a portion of mesentery is protru- ded, it is to be returned before either of the preceding parts. The intestine should al- ways be reduced, unless it be found in a state of actual mortification. It often ap- pears so altered in colour, that an uninform- ed person would deern it improper to re- turn it into the abdomen. However, if such alteration should not amount to areal mor- tification, experience justifies the reduction of the part. Mr. A. Cooper has judiciously cautioned the operator not to mistake the dark chocolate brown discolorations, for a state of gangrene. With these the protruded part is frequently found affected ; and as they generally produce no permanent mischief, they ought to be carefully discriminated from the black-purple, or lead-coloured spots which usually precede mortification. To determine whether a discoloured portion of ifitestine be positively mortified, some re- commend pressing forward the blood con- tained in the veins, and if they fill again, it is looked upon as a proof that the bowel is still possessed of life. In returning a piece of intestine into the abdomen, the surgeon should first introduce the part nearest the ring into this aperture, and hold it there until another portion has succeeded it. This method is to be continu- ed till the whole of the protruded bowel is reduced. Writers on surgery cannot too severely reprobate the employment of any force, or violence, in the endeavours to return the contents of a hernia in the operation : a method the more pernicious, because such parts are more or less in a state of inflam- mation. It is always better to enlarge the stricture, than pinch and bruise the bowel in trying to get it through an opening, which is too small. Distention of the intestine Sometimes prevents the reduction: but when this is the only impediment, the part may generally be returned, as soon as its con- tents have been compressed into the intes- tinal canal within the stricture. It is better, however, to dilate the strangulation a little more, than use any force in trying to get the intestine back into the abdomen in the manner just suggested. Reduction is sometimes impeded by the protruded parts adhering to each other, or to the hernial sac. The intestines are not often found very firmly adherent together. The omentum and inside of the sac are the parts which are most subject to become intimately connected by adhesions. The fingers will commonly serve for breaking any recent slight adhesions which may have taken place between the intestines and in- side of the hernial sac. When those adhe- sions are firm, and of long standing, they must be cautiously divided with the knife •, an object which can be most easily and safely accomplished, in case they are long enough to permit the intestine to" be eleva- ted a little way from the surface of the sac. But, provided their firmness and shortness keep the external coat, of the bowel and inner surface of the sac in close contact, the greatest care is requisite in separating the parts with a knife, so as to avoid wound- ing the intestine In doing this, the most prudent and safe method is not to cut too near the bowel, but vather to remove the adherent parts of the sac, and return (hem with the intestine into the abdomen. Every preternatural connexion should always be separated, before the viscera are reduced : Mr. A Cooper mentions, that a fatal ob- struction to the passage of the intestinal matter has arisen from the mere adhesion of the two sides of a fold of intestine together. ( P . 8i.) When the adhesions, which pre- vent reduction, are situated about the neck efthe sac, and out of the operator’s view, it is best to make the wound through the skin and abdominal ring somewhat larger, so as to be able to separate the adhesions with more safety. Having reduced the parts, the operator should introduce his finger, for the purpose of being sure that they are fairly and freely returned info the abdomen, and no longer suffer constriction, either from the inner opening, from the ring, or the parts just within the cavity of the peritonajum. Treatment of the omentum. In an entero-epiplocele, this part, if heal- thy and free from gangrene, is to be redu- ced after the intestine. When, however, it is much diseased, thickened, and indurated, as it frequently is found to be, after remain- ing any considerable time in a hernial sac, the morbid part should be cut oft’. Its re- duction, in this circumstance, would he highly improper, both because an immode- rate enlargement of the wound would be necessary, in order to be able to put the dis- eased muss back into the abdomen, arid be- HERNIA. 2 is cause, when reduced, it would, in all pro- bability, excite inflammation of the sur- rounding parts, and bring on dangerous symptoms. (See Hey, j>. 172.) The diseased omentum should always be cut oil' with a knife; and if any of its arte- ries should bleed, they ought to be taken up with a tenaculum, and tied separately with a small ligature. An unreasonable appre- hension of hemorrhage from the cut end of the omentum has led many operators to put a ligature all round this part, just above the diseased portion which they were about to remove. This practice cannot be reproba- ted in terms too severe ; for a frequent ef- fect of it is to bring on a fatal inflammation, and even mortification of the omentum, ex- tending within the abdomen, as high as the stomach and transverse arch of the colon. Mr. A. Cooper has remarked with great truth, that it is surprising this custom should ever have prevailed. The very object of the operation is to extricate the omentum from its strangulated state, arising from the pressure of the surrounding tendon, and no sooner has this been done, than the surgeon includes it in a ligature, which produces a more perfect constriction, than that which existed before the operation was under- taken. “ When the omentum has suffered stran- gulation for a few days (says Mr. Lawrence) it often becomes of a dark red, or livid co- lour ; and there is an appearance, on cutting it, as if some blood were extravasated in its substance. This, I believe, is the state which surgeons have generally described under the term of gangrene.” (P. 262.) When cut in this state, it does not bleed. I need hardly observe, that the dead part must be amputated, and never reduced. 9ome have advised leaving the omentum in the wound, especially in cases of old her- nice, in which it has been a long while pro- truded. Hey mentions cases, showing that granulations form very well, and that the wound becomes firmly healed, when this plan is followed. (P. 180, fyc.) Every one ; however, will acknowledge the truth of what Mr. Lawrence says on this subject. The method “ is attended with no parti- cular advantage, but certainly exposes the patient to the possibility of ill consequences. The omentum, left in the wound, must be liable to injury, inflammation, or disease ; and hence arises a source of danger to the patient. Unnatural adhesions, formed by this part, have greatly Impaired the func- tions of the. stomach. Cases are recorded, where the unfortunate patient has never been able to take more than a certain quan- tity of food, without bringing on instant vo- miting ; and even where it has been neces- sary for all the meals to be taken in the re- cumbent position, with the trunk curved, and the" thighs bent. (Guns.) To avoid the possibility of such afflicting consequences, we Should, after removing any diseased por- tion, carefully replace the sound part of the omentum in the abdominal cavity.” (Spe Lawrence on Ruptures, p. 274, Edit. 3) Treatment, when the intestine in t hr sac is mortified. Sometimes, on opening the hernial sac. the intestine is found to be in a gangrenous state, although the occurrence could not be previously known, owing to the integuments and the hernial sac itself not being affected with the same mischief. In ordinary cases, however, both the skin and sac become gangrenous at the same time with the con- tents of the hernia. The tumour, which was previously tense and elastic, becomes soft„ doughy, emphysematous, and of a purple- colour. Sometimes the parts also now spon- taneously return ; but the patient only sur- vives a few hours. Mr. A. Cooper has accurately remarked, that in other instances, the skin covering the swelling, sloughs to a considerable ex- tent, the intestine gives way, and as the feces find vent at the wound, the symptoms of strangulation soon subside. When the patient continues to live in these circum- stances, the living part of the intestine be- comes adherent to the hernial sac, the sloughs separate and come away, and thus an artificial anus is established, through which the feces are sometimes discharged during the remainder of life. (See Anus, Ar- tificial.) Frequently, however, things take a more prosperous course : the feces gradually re- sume their former route to the rectum, and in proportion as the artificial anus becomes unnecessary, it is shut up. Many instances of this sort have fallen under my own ob- servation in St. Bartholomew’s Hospital. The chance of a favourable event is much greater in some kinds of hernia, than in others. When the strangulation only in- cludes a part of the diameter of the gut, the feces are sometimes only partially dis- charged through the mortified opening. This quantity lessens as the wound heals, and the patient gets perfectly well. (Louis, Mem. de VAcad. de Chir. T. 3. P. S. Palm , De Epiplo-tnterocelc crurali incarcerata spha- celata, cum deperditione notabili substantia: intestini , sponte separati, feliciler cur at a alvo naturali restituta, 4 io. Tub. 1748. Haller f Disp. Chir. 3, 2.) A small gangrenous spot, or two, may end in the same manner. Mor- tification, as well as wounds of the large in- testines) is much more frequently followed by a recovery, than the same affection and similar injuries of the small intestines. Mor- tification of the ccecum and its appendix, in a hernial sac, has happened several times, without materially disturbing the usual course of the feces to the anus, and the pa- tients very soon recovered. (Med. Obs. and Inq. Vol. 3. p. 162; Hey's Pract. Obs. p. 162, fyc.) The grand thing, on which the establish- ment of the continuous state of the intesti- nal canal depends, in all these cases, is the adhesion which the living portion of the bowel, adjoining the mortified part, con- tracts with the peritonaeum all round. In this manner, the escape of the content's ot HERNIA. 29 \he bowels into the cavity of the peritonae- um becomes in general completely prevent- ed. The two ends of the sound portion of intestine, after the mortified part has separa- ted, open into a membranous cavity, which previously constituted a portion of the peri- ton&'u' sac, and now unites the extremities of the gut. The gradual contraction of the wound closes the membranous eaviiy exter- nally, and thus (he continuity of the canal is restored. The two ends, however, are not joined so ns to form a continued cylindrical tube, like that of the natural gut ; but they are united at an angle more or less acute, and the matter, which goes from one to the other describes a half circle in a newly form- ed membranous cavity that completes the canal ; a subject which has been more fully explained in another part of this work. (See Anus , Artificial.) It is ai« observation of Mr. A. Cooper’s, that the degree of danger, attending an arti- ficial anu^, depends on the vicinity of the sphacelated part of the intestinal canal to the stomach. Thus, it the opening in the jejunum, there is such a small extent of sur- face for absorption, between it and the sto mach, that the patient dies of inanition. Let us now suppose, that the mortified state of the intestine has only been discover ed, after laying Open the nernial sac in the operation. The mischief may only consist of one or more spots ; or of the whole dia- meter of the protruded bowel, lu the first case, the proper practice is to divide the stricture, and return the intestine into the ab- domen, with the mortified spots towards the wound. Mild purgatives and clysters are then to be exhibited. The most favourable mode, in which a case of this kind ends, is when the intestinal matter gradually resumes its natural course, after being either partly or entirely discharged from the wound. But sometimes the patient sinks under the dis- ease, or an artificial anus continues for life. The repeated observations of modern sur- geons have now decided, that no ligature, passed through the mesentery, to keep the gangrenous part of the bowel near the wound, is at all necessary. The parts, in the neighbourhood of the ling, have all become adherent together, in consequence of inflam- mation, at the same time that the parts in the hernial sac mortify ; and of course, the partially gangrenous bowel, when reduced, is mechanically hindered, by these adhesions, from slipping far from the wound. Desault and De la Faye, both confirm the fact, that the intestine never recedes far from the ring; and even were it to do so, the adhesions, which it soon contracts to the adjacent sur- faces, would, as Petit ha3 explained, com- pletely circumscribe any matter which might be effused, and hinder it from being exten- sively extravasated among the convolutions of the viscera. (Mem. de VAcad. de Chir. T. 1, 2.) Where the chief part, or the whole of the diameter of the protruded bowel is mortified, the first and most urgent indication is to re- lieve the bad symptoms arising from the dis- tention of the Intestinal canal above the stricture. “ Let a free incision (says Mr. Lawrence) be made through the mortified part of the gut, in ord»-rto procure that eva- cuation of the loaded canal, which nature attempts by the process of gangrene.” If the intestine has already given way, a free divi- sion of the integuments and sac allows the exit of the accumulated matter ; and the opening in the gut may be enlarged, if ne- cessary. (Lawrence on Ruptures, p. 283.) Here the division of the stricture is unne- cessary, since all the mischief, which the bowel can receive from it, is done This subject is well explained by Mr. Travers. (See Inq. into the Process of Nature in Re- pairing Injuries of the Intestines, tyc. p. 300, fyc.) Mild purgatives and clysters will be proper to unload the bowels, and determine the course of the feces towards the anus. Should, however, the stricture appear after Ihe mortification, to impede the free escape of the inteslina 1 contents, a moderate dilata- tion of it must undoubtedly be proper. Mr. Lawrence, in his valuable Treatise on Ruptures, has clearly exposed the improprie- ty of sewing the ends of the intestinal canal together, introducing one within the iher, supported by a cylinder of isinglass, &,c, put in their cavity, in those cases, in which the whole circle of the intestine lias mortified, and been cut away, a? was advised by for- mer writers. By drawing the intestine out of the cavity, in order to remove the dead part, the adhesion behind the ring, on which the prospect of a care chiefly depends, must be eo'irely destroyed ; and new irritation and inflammation must be unavoidably pro- duced, by handling and sewing an inflamed part. (See Lawrence on Ruptures , p. 298, 4 *.) Instead of such practice, this gentleman judiciously recommends dilating the stric- ture, and leaving the subsequent progress of the cure entirely to nature. The sloughs will be cast off, and the ends of the gut are retained by the adhesive process in a state of apposition to each other, the most favour- able for their union. Thus, there is a chance of the continuity of the intestinal canal be- coming established again. Whatever experiments it may be allow- able to make in wounds with protrusion and division of the bowels, nothing, l think, is now more completely established, than the absurdity and danger of attempting to stitch the bowels in cases of hernia. OPERATION FOR VERY LARGE INGUINAL HERNIAL When the tumour is of long standing, ex- ceedingly large, perhaps extending half way down to the knees, and its contents have never admitted of being completely reduced, the indication is to divide the stricture, pro- vided a strangulation takes place ; but with- out laying open the hernia! sac, or attempting to reduce the parts. The reasons against the common plan of operating, under such circumstances, are, HERNIA 30 thfi difficulty of separating all the old adhe- sions ; the hazardous inflammation, which would be excited by laying open so vast a tumour, and the probability that ports so long protruded, might even bring on serious com- plaints, if reduced. J. L. Petit, and after- ward Dr. Monro, advised the sac not to be opened. (See Mai. Chir. T. 2, p. 372. De- scription of Bar see Mucosae, 1788.) OPERATION WHEN THE HERNIA IS SO SMALL THAT IT DOES NOT PROTRUDE EXTERNAL- LY THROUGH THE RING. In this kind of case, there is little appear- ance of external tumour; consequently, the disease is very apt to be overlooked by the patient and surgeon, and some other cause assigned for the series of symptons. The manner of operating, in this form of the disease, differs from that in the common scrotal hernia ; the incision is to be made pa- rallel to the direction of the spermatic cord, and the stricture will be found at the inter- nal ring. (H. Cooper on Inguinal Hernia.) TREATMENT AFTER THE OPERATION. Evacuations from the bowels should be immediately promoted by means of clysters, oleum ricini, or small doses of any of the common salts, dissolved in peppermint water. For some time, the patient must only be al- lowed a low diet. When symptoms of in- flammation of the bowels and peritonaeum threaten the patient, general bleeding, leeches applied to the abdomen, fomentations, the warm bath, blisters, doses of the oleum ricini, and clysters, are the means deserving of most dependence, and should be resorted to without the least delay. When all danger of peritonaeal inflammation is past, and the pa- t i e n t i s v e r y 1 o vv a n d w e a k , b a r k , w i n e , c o r d ia] s > and a generous diet, must be directed. The effervescing saline draught, with opium, is the best medicine for quieting' sickness, after the operation. Opium and cordials are the most eligible for checking diarrhoea. As the operation does not usually prevent the parts from becoming protruded again, a truss must be applied before the patient leaves his bed, and afterward constantly worn. PROPOSALS FOR THE RADICAL C\lRE OF THE Bubonocele, Of castrating the patient, applying caustic, or of the operation of the punctum aureum, with this view, I need only say, that they are barbarous, and not at all adapted for the at- tainment of the desired end. A description of these methods may be found in Pare, Wiseman, &c. The old operation, termed the royal stitch, was one of the most promising plans. It consisted in putting a ligature under the mc< ko( the hernial sac, close to the abdomi- nal ring, and then tying that part of the sac. as to render it impervious, by the adhesive inflammation tbu= excited. The royal Milch, performed in tins manner, has been actually attended with success, ( Heist er , Vol. 2.) The umbilical rupture was cured by Saviard, on similar principles > and Desault radically cured nine cases of the exomphalos in children, by tying the hernial sac. Sehmucker cured two irreducible ruptures, free from strangulation, by cutting away the body of the sac, after tying its neck (Chir. Wahrnehmungen , B. 2.) In one case, Mr. A. Cooper found cutting away the sac, alone insufficient. Dissecting away ihe whole hernial sac, or even laying it open, must be a formidable operation, compared with merely making a small incision down to the neck of the sac, and applying one ligature. If the hernia were reducible, and the upper part of the sac could be rendered impervious by the li- gature, all other more severe plans would be superfluous. However, Petit, Sharp, Acrel, &c. record cases, which tend to prove the danger and inefficacy of the royal stitch ; though it is true, that none of these surgeons operated exactly in the simple manner above suggested. Richter recommends scarifying the neck of the sac, with the view of producing an ad- hesion of its sides to each other ; a plan, which, he says, he found very successful. From the account, however, which has been given of the anatomy cf the bubono- cele, it is obvious, that none of these me- thods could do more than obliterate the sac as high as the ring, and never that portion of it, which is within the inguinal canal. Hence, the neck of the sac must still remain open for the descent of the viscera. This consi- deration, and that of the chances of bad and fatal symptoms from any operation un- dertaken solely for this purpose, and not urgently required for the relief of strangula- tion, are the grounds on which these experi- ments are now disapproved. CRURAL, OR FEMORAL HERNIA. Verheyen, who wrote in 1710, first de- monstrated the distinct formation of crural hernia, which umil then had been generally confounded with bubonocele. The parts, composing this kind of hernia, always protrude under PouparPs ligament, and the swelling is situated towards the inner part of the bend of the thigh. The rupture descends on the inside of the femoral artery and vein, between these vessels and the os pubis, through the crural ring, or canal for the transmission of the same vessels. And, as Hesselbach has remarked, the inner open- ing of this ring or canal is the predisposing cause of the disease, t lie peritonaeum spread over it, being gradually propelled into it by various occasional causes, so as to complete the tendency to hernia. The actual pro- trusion of the bowels may be formed either suddenly, or by degrees. As soon as the. bowels have once passed the outer npertare, or what Cloquet terms more properly the lower opening of the crural canal, the hernia has more room for extending itself forwards', HERNIA. 31 and (o each side, and (he integuments now become elevated into an aval swelling , the long diameter of which is nearly transverse. ( Hesselbach , p. 47.) Girnbernat names the passage through which the femora! hernia pro- trudes from the abdomen, the crual ; Iley, the femoral ring; and Cloquet, the crural ca- nal. Females are particularly subject to this kind of rupture. It has been computed, that nineteen out of twenty married women, af- flicted with hernia, have this kind ; but, that not one out of an hundred unmarried fe- males, or out of the same number of men, have this form of the disease. ( Arnaud .) “ The crural hernia,” says Scarpa, is fre- quently observed in women who have had several children ; it very seldom afflicts young girls ; and still more rarely men. In the latter, the viscera can more easily escape through the inguinal ring, by following the spermatic cord, than they can descend along the crural vessels, and raise the margin of the aponeurosis of the external oblique mus- cle, that forms the crural arch. In women, an opposite disposition prevails, in conse- quence of the smallness of the inguinal ring, which, in them, only gives passage to the round ligament of the uterus, and besides, is situated lower down, and nearer the pubes, than it is in men, whilst on the contrary, the crural arch is more extensive, by reason of the wider form of the pelvis. Morgagni ex- pressly says, that Ire never met with the cru- ral hernia in the dead body of any inale sub- ject. Mild, ut verum fat ear , nondum nisi in feeminis accidit lit earn viderem. (De sed. et caus.morb. Epist. 34, 15.) Camper gives us " to understand almost the same thing. (I cones Herniarum , in Prcefat.) Hevin often opera- ted for this kind of hernia in females, but only once in the male subject. ( Pathol . et Thttup. p. 406.) Sandifort and Walter have both seen but a single instance of ii in the dead body of the male subject. ( Ohs . Anat. Pathol, cap. 4, p. 72. Sylloge comment, anat. p. 24, obs. 21.) Arnaud himself, to whom modern surgery is highly indebted for many important precepts on the operation for the strangulated crural hernia in both sexes, candidly confesses, that he never had an op- portunity of dissecting a hernia of this kind in the male subject.” ( Scarpa , TraiU dcs Hernies.p. 201.) Scarpa bad at his disposal a male subject, in which there was a crural hernia, and he availed himself of the opportunity of exami- ning the parts with the utmost care. He first injected the blood-vessels ; he after- ward attentively dissected all the parts con- cerned in the disease ; and he has published an exact description of the particulars, illus- trated by an engraving. According to Hesselbach, the femoral hernia, though not common in men, is more frequent than is generally believed, and often overlooked on account of its being very small. ( Ueber den Ursprung, Spc. der Leisten-und-Schenkelbriiche, p. 47.) Thus, in an example published in a modern work, an inguinal and femoral hernia were met with together in a gentleman, sixty-three years of age. On examination of the body after death, a small piece of intestine, form- ing a crural hernia, was found strangulated, and concealed under an inguinal rupture and a mass of fat. (C. Bell's Surgical Obs. Vol. 1, p. 187.) According to the observations of Scarpa, and all the best modern writers upon sur- gery, the crural hernia forms, both in the male andfemale subject, in the cellular sub- stance, which accompanies the crural ves- sels below Poupart’s ligament. The swelling follows the internal side of those vessels, and gradually descends into the fold of the thigh, between the sarlorius, gracilis, and pectineus muscles. u Many surgeons be- lieve (says Scarpa,) that the hernial sac, and the intestines, which it contains, are or- dinarily situated above the crural vessels arid trunk of the vena saphena, and some- times between these vessels and the anterior superior spine of the ileum. But as far as my knowledge extends, this assertion is not supported by a single accurate descrip- tion of the crural hernia in the early stage. It is true, that when the tumour has in time acquired a large size, and its fundus is incli- ned in a parallel manner to the fold of the thigh, it partly or entirely covers the cru- ral vessels, and even the crural nerve, as Walter says he once observed. ( Sylloge comment, ana!, p 24.) But it is not thence to be concluded, that the tumour in the be- ginning descended over the crural vessels, much less betwixt them and the anterior superior spinous process of the ileum. Nei- ther must it be imagined, that the neck of the hernial sac becomes removed from the inner to the outer side of these vessels. If these two cases ever happen, they must be very rare ; and the best authors who have treated of crural hernia, concur in stating, that in performing the operation, they have constantly found the viscera situated on the inside of the crural vessels, but never on their outsidTe. Even when the tumour, after acquiring a considerable size, is situated transversely over the crural vessels, the neck of the hernial sac has always been found upon their inner side, that is to say, between them and the pubes. Le Dran, ( Observ . de Chir. T. 2. p. 2.) La Faye, ( Cours d' Operations de Dionis, p. 358.) Petit, ( (Euvres Pasthurnes, T. 2, p. 219.) Morgagni.. (De Sed. et Cans. Mcrb epist. 34, 15.) Arnaud, (Mem. de Chir. Tom. 2, p. 768.) Gunz, (De Hcrniis libeilus, p. 78.) Bertrandi, (Trallato delle Operazoni, T. 1, annot.p. 218.) Pott, (Chirurg. Works, Vol. 2, p. 152.) Desault, (Traite des Mai. Chi- rurg. p. 191, 195.) B, Beil, (A System of Surgery , Vol. 1, p. 387.) Richter, (Traite des Hernies, chap. 34.) Nessi, (Instituz. Chir. T. 2, p. 198.) Lassus, (Med. Oper. T. 1, p. 198.) and many other writers, all concur upon this point. In support of their opi- nion, (says Scarpa,) I could cite a great number of cases of my own, which I have collected either in operating on several in- dividuals for crural hernia, or in dissecting 32 HERNIA. the same kind of hernia in the bodies of many female subjects, and in that of the man, from whom I have taken the 8th plate. Lastly, also, having had an oppor- tunity of dissecting in a female an enor- mous crural hernia, which descended one- third of the way down the thigh, I observed that the ne k of Ijjie sac did not encroach at all upon the r rural vessels, but lay entirely on their inner side.” ( Scarpa , Traili des Hernies, p. 203, 206.) The tumour, on account of its situation, is liable to be mistaken for an enlarged ingui- nal gland; ant 1 man; fival events are re- corded to have happened from the surgeon’s ignorance of the existence of the disease. Air. Lawrence once saw an hospital sur- geon mistake a crural hernia for a glandu- lar tumour, and the patient died, without any attempt being made to afford relief by the operation. fP. 391. See also Petit , Traiii die s Mai. Chir. T. 2, p 293, fyc.) A gland can only become enlarged by the gradual effects of inflammation ; the swell- ing of a crural hernia comes on in a mo- mentary and sudden manner, and when strangulated, occasions the train of symp- toms already described in our account of the inguinal her iu, which symptoms an enlarged gland could never occasion. Such circumstances seem to be sufficiently discri- minative ; though the feel of the two kinds -of swelling, is often not of itself enough to make the surgeon decided in his opinion. It is particularly remarked by Hesselbach, that, while a femoral hernia is incomplete, that is to say, within the outer opening of the passage, through which the parts de- scend, ;the disease presents itself as a round firm swelling, on the outer side of which the femoral artery can be felt pulsating: this small hernia may be mistaken for an in- flamed giand, and the case can only be dis- criminated by the history of its origin and symptoms. ( JJeber den Ursprung dcr Leis- ten-i. J-Schenkelbriiche, p. 51.) A femoral hernia may be mistaken for a' Bubonocele, when the expanded part of the swelling lies over Poupart’s ligament. As the taxis and operation for the first case ought to be done differently from those for the latter, the er- ror may lead to very bad consequences. The femoral hernia, however, tr.ay always he discriminated, by the neck of the tumour hav- ing Poup art's ligament above it. In the bu- bonocele, the spine of the pubes is behind and below this part of the sac; but in the femoral hernia , it is on the same horizontal level, and a little on the inside of it. (See Lawrence on Ruptures, p. 392, 393, Ed. 3.) In the male subject, 11 the crural hernia, in the early stage, (says Scarpa) is situated so deeply in the bend of the thigh, that it is difficult, even in the thinnest persons, to feel its neck, and in examining its circum- ference with the extremity of the finger, the tendinous margin of the opening, through which the parts are protruded, can only be perceived with considerable diffi- culty. On the contrary, the inguinal her- nia. however small it may he, is always less deeply situated ; it is about half an inclt above the bend of the thigh. In carrying the finger round its neck, the tendinous margin of the inguinal ring can be easily felt at its circumference ; and at the poste- rior part of the small tumour, the cord com- posed of the spermatic vessels is distin- guishable. When the crural hernia has ac- quired a considerable size, its neck is always deeply situated in the bend of the thigh ; but its body and fundus assume an oval form, and their great diam eter is situated transversely in the bend, of the thigh. Whatever may be the size of the inguinal hernia, it al ways pre- sents a tumour of a pvramidal form, the base or fundus of which; far from being di- rected towards the ileum, follows exactly the direction of the spermatic cord, and descends directly into the scrotum. Be- sides the symptoms, common to all hernial swellings, the crural hernia, when it has attained a certain size, presents some others which are peculiar to it, such as a sense of stupor and heaviness in the thigh, and oedema of the leg , and even of the foot, of the same side.” The reason, why oedema and numb- ness of the limb, are particularly remark- able in cases of femora hernia, is justly re- ferred by Hesselbach, to the circumstance of the femoral vessel? and nr es, with nume- rous lymphatics, taking their course through the crural ring, and according to his observa- tion;, the numbness and cedema an especial- ly great, when the protrusion is omentum, which makes stronger pressure on the ves- sels and nerve?, than commonly happens in a case of entereeele. (P. 53.) “ In women, however, as Scarpa observes, it is less easy j distinguish the crural hernia from the inguinal. In fact, the absence of the spermatic cord, and the nearer situation of the ring to the crurat arch, may easily occa- sion a mistake. Sometimes, a woman may even be supposed to have a double crural hernia pf the same side, whilst, of these two distinct, though neighbouring^!, urniffi, one may be inguinal, and the other crural. Ar- naud (Mem- de Chir. T.2.p 605,) relates an instance of such a mistake.” ( Scarpa , Trait6 des Hernies, p. 207,208.) This interesting writer take occasion to observe further, upon t his part |of the sub- ject, that the portion of the inferior pillar of the abdominal ring, which separates this opening from the internal and inferior angle of the crural arch, is so ^slender in women, that it is sometimes hard to distinguish the crural from the inguinal hernia, which is not the case in male patients. Until a few years ago, the stricture, in cases of femoral hernia, was always supposed to be produced by the lower border of the external oblique muscle, or, as it isjtermed, Poupart’s ligament. A total change of opi- nion on this subject, however, Ims latterly taken place, in consequence of the observa- tions first made by Gimberuat, in 176S. “ In the crural hernia, (says he) the aperture through which the parts issue, is* not formed by two bands, (as in the inguinal hernia) but it is a foramen almost round, proceeding DERMA. 33 from the interna] margin of the crural arch (Pounart’s ligament,) near its insertion into the branch of the os pubis, between this bone and thejiliac vein ; so that, in thisjher- nia, the branch of the os pubis is situated more internally than the intestine, and a little be- hind ; the vein, externally, and behind ; and the internal border of the arch, before. Now it is tliis border which always forms the strangu- lation.’’ (See A new Method of Operating for the Femoral Hernia , bp Don Antonio dc Gimbernat , p. 6, Trans, by Beddoes.) The utility of knowing, that it is not Pou- part’s ligament which produces the strangu- lation, in cases of femoral hernia, is import- ant ; for we then know, that cutting the lower and outer border of the external ob- lique muscle, is quite erroneous. This pro- ceeding is the more to be reprobated, because the lower pillar of the abdominal ring, in both sexes, will be divided by directing the incision upward, or upward and inward ; and thus the abdominal a id crural rings will be made into one common aperture, large enough to make the future occurrence of hernia very likely to happen. In the male, there is also considerable danger of the spermatic cord being cut. Cutting Pou- part’s ligament obliquely outwards, is attend- ed with still more danger ; for the epigastric artery will infallibly be divided at ils origin ; and with all these hazards, the incision must be quite useless, unless carried on to the in- ternal edge of the crural arch. ( Gimbernat , p. 16.) Tiie inclination, however, of several mo- dern writers to refer the strangulation en- tirely to Gimbernat’s ligament, is not sanction- ed by the most careful observers, like Hes- seibach and Langenbeck, (JVeue Bibl. B. 2. p. 132.) The former justly remarks, that a complete femoral hernia may be strangula- ted in two places, either at the out&r or in- ner opening of the passage, through which the protrusion happens. Nay, says he, that the strangulation is sometimes caused by the outer opening, was known to former sur- geons, for they remarked, that the constric- tion was removed by dividing the fascia. (P. 53.) And, in addition to these two modes of strangulation, is to be enumerated a third, in which the viscera are constricted by protruding through' some weaker point, or accidental opening, in the anterior parie- tes of the crural canal (Hesselbach, p. 4S ; also Langenbeck , Op. cit. p. 132,) or even through an aperture in the inner side of this passage, ns we find depicted in the twentieth plate of Langenbeck’s treatise, “ De Struc- ture Peritonmi.” 1 know of no surgical writer, who has given a clearer account of the anatomy of the femoral hernia, than Langenbeck (JVeue Bibl. B.2,p. 112, ^y-c.) He observes, that when the dissection is begun at the inside of the inguinal region, the following circum- stances are noticed : after the removal of the peritonaeum from the abdominal muscles, and from the psoas, iliacus interims, and the great vessels, the inner surface of the trans- versalis still has an investment, which Clo- Vol. O. 5 quet terms the fascia Iransversalis, and which is always a white glistening aponeurosis. From the place, where the femoral artery lies under Poupart’s ligament, to the anterior superior spine of the ilium, the preceding fascia is extended in a strong fibrous form behind the inner surface of Poupart’s liga- ment, and a thin continuation of it is ex- tended over the iliacus interims and psoas muscles, where it is named by Mr. A. Coop- er and Cloquet the fascia iliaca. The fascia of the transverse muscle closes the belly be- hind Poupart’s ligament, as completely as the peritongeum does, so that between the femoral artery and the anterior superior spine of the ilium none of the bowels can protrude, which occurrence is still further prevented by the fascia lata, which below Poupart’s ligament is closely attached to the muscles of the thigh By the pelvis being thus shut up, the origin of a crural her- nia on the outside of the femoral vessels is rendered quite impossible. (Langenbeck, op. cit.) This part of the explanation very nearly resembles that delivered by Mr. A. Cooper, except that the latter describes the iliac fas- cia, and not what Cloquet calls the trans- verse fascia, as closing the pelvis from the spine of the ilium to the crural vessels. But, this diiTerc.ee is easily accounted for by the circumstance of Mr. A. Cooper extending the name fascia iliaca beyond the limits given it by Cloquet and Langenbeck. Near the anterior superior spinous process of the ilium, Langenbeck remarks that the fascia of the transverse muscle has some strong fibres, which proceed inwards under the internal opening of the inguinal canal, of which they form, as it were, the bottom, and are named by Hesselbach the internal inguinal ligament. They go over the femo- ral artery and vein, are connected above with the fascia of the transverse muscle, and below are continued into the fascia of the psoas and iliac muscles. Where these fibres pass over the femoral vessels, they expand into a firm aponeurosis, which passing down- wards, is intimately attached at the inner side of the femoral vein to the horizontal branch of the os pubis, close to the symphv- sis, and then joins the aponeurosis of the recti muscles. The expanded portion of the foregoing tendinous fibres, thus continu- ed along the crista of the os pubis to the sheath of the rectus, forms the inner surface of Gimbernat' s, or the femoral or crural liga- ment.. The inner edge of this ligament is falciform, and concave, the concavity being turned towards the femoral vein. Now where the fascia of the transverse muscle extends downwards, on the outer side of the crural artery, to the fascia of the psoas and iliac muscles, so as to close the pelvis between that vessel, and the anterior supe- rior spinous process of the ilium, it also forms, like Gimbernat’s ligament, a falciform edge, the concavity of which lies close over the external convexity of the crural artery. Thus, partly by the concave edge of Gimber- nat’s ligament, directed towards the crural vein, find partly by the conclave edge of the ukrNU. 34 extension of the fascia of the transverse mus- cle to the fascia iliaca, which edge is turned towards i he crural artery, an aperture is pro- duced, through which the femoral vessels pass out of the pelvis. This opening is named by Cloquet the upper opening of Ike crural canal , or as many English surgeons would say, of the crural or femoral ring. By Hesselbach, it is called the internal opening for the femoral vessels. However, as these vessels do not lie loosely and uneonnectedly in this aperture, the opening itself is shut up, as it were, and cannot be seen without dis- section. On the above described fasciae, there is a considerable quantity of cellular substance, which covers the vessels in the pelvis, forms a sort of sheath for the crural artery and vein, and accompanies these vessels through the inner opening of the crural canal, or ring, which is itself accurately shut up by it. When this celluiarsubstance is removed, the white glistening fascia; are plainly seen pass- ing through the same opening, and coming nearer together in a funnel-like manner. 'Where the fascia of the transverse muscle forms the outer falciform edge of this aper- ture, and is passing over the arteria circum- ilexa ilii to the psoas and iliac muscles, it sends off' through the opening a process, which becomes connected with the outer side of the crural canal, or ring : while from the internal inguinal ligament, which lies above this opening, and constitutes the upper edge of the inner aperture of the crural canal, a production is sent, which is connect- ed with the anterior side of this canal. As for the posterior and inner sides, they have a connexion with the fasciae of the psoas and levator ani. When the groin is externally dissected, in order to have a view of the crural ring or canal, on the outside of the pelvis, the fol- lowing appearances present themselves: after the removal of the common integu- ments, one finds below Poupart’s ligament, a quantity of fat, glands, lymphatics, veins, and arteries, which vessels come out through small openings in the fascia lata. As soon as the outer surface of the external oblique muscle is cleared, its aponeurosis is found to become stronger at the anterior superior spinous process of the ilium, and its fibres to collect together, and assume the form of a band, which is Poupart’s ligament, called by Hesselbach the external inguinal liga- ment, and by Gimbernat, Cloquet, and others, the crural arch. This ligament, as is well known, passes obliquely inwards and down- wards towards the os pubis, and after form- ing the external pillar of the abdominal ring, is first closely inserted into the angle or tu- bercle of the os pubis, and then being con- tinued inwards, or backwards, in the form of a firm fascia, is attached to the horizon- tal ramus of that bone, making the anterior or outer surf ace of Gimbernal's, or the femoral, ligament , w hich is consequently produced by the junction of Poupart’s w'ith Hessel- bttch's internal inguinal ligament along the ?»j»ine of the os pubis. Thus, just as the in- ternal inguinal ligament is a strengthened part of the fascia of the transverse muscle, the outer inguinal ligament, (or, as it is here commonly called) Poupart’s ligament, is pro- duce! by the. strengthened fibres of the low er portion of the aponeurosis of the external oblique muscle, the fibres of it making the external pillar of the ring, being continued further towards the symphysis of the pubes, in the form of the outer surface of Gim- bernat’s ligament. ( Langenbeck , JYeue Bibl. B. 2, p. 120, 121.) English surgeons make the formation of Gimbernat’s, or the fe- moral ligament more simple : thus Mr. Lawrence states, that w 7 hen Poupart’s liga- ment approaches the pubes, “ it becomes suddenly broader; that it is fixed by this broad portion, along the whole length of the angle and crista of the pubes ; that it has a rounded and strong anterior edge, a thin and sharp posterior margin ; and that the former of these is nearer to the surface, while the latter is comparatively deeply seat- ed. The breadth of this part varies, in dif- ferent subjects : it is generally from three quarters of an inch to an inch Sometimes, as Gimbernat has stated, it measures more than an inch. Dr. Monro has observed, that it is broader in the male than in the female subject; and from this structure, he ex- plains in part the more rare occurrence of this rupture in the male.” (P. 368, Ed. 3.) The fascia lata, which is spread over the muscles of the thigh, is only a continuation of the aponeurosis of the external oblique muscle, and, as it proceeds downwards from Poupart’s ligament, is very closely attached to the muscles of the thigh, all the way from the anterior superior spinous process of the ilium, to the femoral artery, drawing as it Avere Poupart’s ligament dowmwards and in- wards, or backwards, towards the cavity of the pelvis, so as to give to its external edge a convex appearance, and shut up the out- side of the pelvis, from the anterior superior spine of the ilium asfarasthe crural nerve and artery, so firmly, that the formation of a femoral hernia at this part is impossible. And, if small apertures, filled with fat, be discernible in this portion of the fascia lata, still no hernia can here take place, because, as Langenbeck has already explained, here the interior of the pelvis is again shut up by fascia* already described. Under the fascia lata are situated the an- terior crural nerve, the vein and artery. The vena saphena magna lies on the outside of it, and passes through an opening in it into the femoral vein. This aperture in the fas- cia lata is at the inner side of the groin, op- posite the internal opening of the crural ring, or canal It is named by Hesselbach the external aperture for the femoral vessels , and desci’ibed by him as an oblique fissure about fifteen lines in length. He takes no- tice of its external semilunar edge, and two horns, which are directed inwards ; the parts first particularly described by Mr. A. Burns of Glasgow, under the name of the semilu- nar, or falciform process of the fascia lain. HERNIA. 3 * The lower born bends rather inwards and upwards, and terminates in the production oi' the fascia lata spread over the pectinalis muscie. The upper horn, which is less cur- ved, buries itself under tiie external pillar of the abdominal ring. Over the lower horn of the opening, just now described, the vena saphena magna ascends into the femoral vein. Through the same aperture also pass nearly all the superficial lymphatics of the lower extremity. According to Cloquet, the fascia lata consists of two layers, of whn h the anterior superficial one is closely attach- ed to the crural arch, extends over the femo- ral vessels, and forms the anterior side of the crural canal. The other layer, near the pubes, quits the former, and, covering the pectinalis muscle, constitutes the hinder side of that canal. The anterior layer of the fascia then forms an oval aperture, through which the vena saphena passes, and which is considered by Cloquet as the lower- opening of the crural canal. This opening, called by Hesselhach the external foramen for the femo- ral vessels, is well delineated both in li is ex- cellent work, and in the twenty-third plate of Langenbeck’s book (De Strudura Perilo- ned, testiculorum tunicis, fyc. 8vo. Goll. 1817.) According to the investigations of the last anatomist, as soon as the integuments are removed, this opening in the fascia lata, with its external semilunar edge, and two horns, are regularly seen. The front side of the crural canal is formed by the fascia lata. Where this fascia proceeds in the form of Hes- selbach’s upper horn under and behind the ex- ternal pillar of the abdominal ring, and makes the outer layer of Gimbernat’s ligament, it is continued as a thin aponeurosis over the vena saphena, so that it makes not merely the upper horn, but reaches further downwards, and forms the outer side of the crural canal. The outer side then of the crural canal, or ring, according to Langenbeck, extends from the outer semilunar edge of the external open- ing for the femoral vessels, or, as English surgeons would say, from tiie edge of the falciform process of the fascia lata. The larger the preceding thin continuation of fascia is, ihe smaller is the external opening for the femoral vessels, the more is the upper horn bent downwards, and the more determinate is the form of the canal. ( Langenbeck , JYeue Bibl. B. 2. p. 124, 125.) According to Mr. Lawrence, “ the fascia lata, or fascia of the thigh, has two distinct insertions at the upper and anterior part of the limb. It is attached to the front edge of the pubes, over the origin of the pecti- neus, the fibres of which it closely covers, and it is also fixed to the front of the crural arch. The former of these is continuous, behind the femora! vessels, with the iliac fascia : the latter is not inserted along the whole length of the tendon, its attachment ceasing on the inner side of the vessels, which it covers anteriorly. Here, therefore, the femoral artery and vein are interposed between the two divisions.” (On Ruptures, Edit. 3, p. 371 . ) Where the insertion of the fascia lata into Poupart’s ligament ends, it forms what Mr. Burns of Glasgow calls the falciform process, the upper part of which is attached to the above ligament, while the lower pro- ceeds further down the thigh. The concavi- ty of the f-dciform process is directed to- wards the pubes. This anatomical connex- ion is one chief cau^e, why extending the thigh, and rotating it outward, render the crural arch tense. The hernia, being situated in front of the pectineus, must of course be exterior to the fascia lata. In my opinion, surgeons are very much indebted to Mr. Lawrence for his able explanation of this fact. As for myself, I am candid enough to own that, until I read his clear and concise account of the anatomy of the crural hernia, I could never reap any accurate notions, concern- ing t!i e relative situations of the hernial sac and fascia of the thigh, from other more prolix works, with the exception of those of H esselbach and Langenbeck, by whom the anatomy is made perfectly intelligible. Mr. Lawrence reminds us. however, that the particular crural hernia, contained in the sheath of the femoral vessels, lies under the fascia ; p. 382, Edit. 3. And he men- tions, that the falciform process of the fascia lata, passes along the upper and outer part of the tumour. The iliac vein is placed on the outer side of the neck of the sac ; thf pubes is directly behind it ; and the upper and inner pans are bounded by the thin posterioredge of Poupart’sligamCnt. The inner side of the crural ring or ca- nal, as already explained, is connected with the fascia of the transverse muscle. And, according to Langenbeck, below the part of the fascia lata, which forms the external foramen. for the femoral vessels, the front side of the crural canal is sometimes form- ed by a continuation of the fascia of the transverse muscle, as he found was the case in both groins of one female subject. In such a case, there is a good deal of fat be- tween the fascia lata, and the aponeurosis of the transverse muscle, and the two parts are easily separable. Langenbeck admits, however, that the same appearance may arise from a splitting of the layers of the fascia lata. Frequently the front side of crural ring is so short, that the opening cannot rightly be termed a canal, and it is always shorter than the posterior side. When the outer side exits, it is extended across the inner over the space between the two horns, and is then connected with the aponeurosis of the pectinalis derived from the fascia of the psoas and levator ani muscles. In the anterior and inner sides of the crural canal, there are some small open- ings. Doubtless, tills stricture is referred to by Hesselhach, when he says, that, in the male subject the outer opening for the fe- moral vessels is further closed by a net-like web of tendinous fasciculi. The posterior side of the crural canal, or ring, is entirely formed by the part of the fascia of the psoas, which enters its inner opening, and joins the aponeurosis of the pectinalis mus- 36 HERNIA. cle. The outer side of the canal lies under the fascia lata, and joins the anterior and posterior sides, where the aponeuroses of the transverse and iliac muscles proceed to the outside of the femoral artery. Langeu- beek thinks the opening, by which the vena saphena passes over the lower horn of the falciform process of the fascia lata, might be named the lower aperture of ilie crural canal. (See Langmbeck's JVeue Bibl. far die Chirurgie, B. 2, p. 126, 127. 8vo. Ha- nover 181b.) According to Hesselbach, in femoral her- nia, tne two openings of the passage now termed the crural or femoral ring, are one half larger than natural. The outer portion of the inner of these apertures is propelled more outward, and with it the epigastric ar- tery. The femoral vein no longer lies at the external end of this opening, but rather at the back of the canal or passage. The external semilunar edge (the falciform process) of the outer opening, is carried more outward and upward, and is tightly ap- plied over the distended hernial sac. In this state of the parts, the outer opening forms an oval firm tendinous ring, the di- rection of which, like that ot the inner opening for the passage of the femoral ves- sels, is transverse. The neck of the hernial sac is that portion of it, which lies within the canal between the two openings. The posterior side of this canal, or passage, now frequently named the crural, or femoral ring, is longer than the anterior. In one large hernia, Hesselbach found it an inch and a half in length, but the anterior side of the passage more than one-third shorter. The greatest diameter of the inner opening was one inch five lines, while that of the outer one was only one inch four lines. Most of the posterior part of the neck of tho hernial sac, with the hinder side of the ca- nal lies upon the peetineus muscle, and towards the outerside upon the femoral vein. The neck of the hernial sac adheres more firmly to the anterior, than to the posterior side of the passage. At the outer opening of the passage, the neck terminates at almost a right angle forwards in the body of the sac, the upper portion of which lies upon Poupart’s ligament, but the largest part of it is situated on the deep-seated layer of the femoral fascia, by which the outer side of the body of the sac, as bigh as the neck, is separated from the crural vessels and nerves. In the male subject, when the tendinous fibres, mixed with the cellular substance covering the outer opening of the passage, make great resistance at par- ticular points, the hernial sac of a femoral hernia may be double, or even divided into several pouches, a preparation exhibiting which occurrence- is in the anatomical museum at Wurzburgh. ( Hesselbach , p. 48.) Except in a few cases, in which the origin and course of the epigastric artery are unusual, this vessel runs very close to the external side of the neck of the hernial sac, much nearer than it does in an internal bubonocele. The sac of the femoral hernia is exceed- ingly narrow at its neck ; and, where its body begins, it becomes expanded in a globular form ; the sac of the bubonocele is generally of an oblong pyramidal shape. The body of the sac of the femoral hernia, makes a right angle with the neck, by being throw n forward and upward, a circumstance very necessary to be known in trying to reduce the parts by the taxis. Though the tumour, formed by the body of the sac, is oval and nearly transverse, it is found, when attentively examined, to take the direction of the groin, which extends obliquely downwards and inwards, the outer, rather smaller end of the swelling being somewhat higher than the inner. (Hesselbach, p. 60.) The sac of the femoral hernia is said by Mr- A. Cooper to be immediately covered by a kind of membranous expansion, con- sisting of condensed cellular substance, and named by him, the fascia propria. Accord- ing to the same gentleman, a weak aponeu- rosis derived from the superficial fascia of the bend of the thigh, also covers the swell- ing, and is described as lying immediately beneath the skin and adipose substance. Under this fascia is the condensed cellular substance, or fascia propria, then some adi- pose substance, and lastly the true perito- meal sac itself. It is of infinite use to re- member these circumstances in operating, lest one should think the hernial sac divided w hen it is not so. All late writers on hernia, have remarked how very small the aperture is, through which the viscera protrude in the femoral rupture ; how much greatertbe constriction generally is, than in the bubonocele ; con- sequently, how much more rapid the symp- toms are ; how much less frequently th© taxis succeeds ; andhow r much more danger- ous delay proves. (See A. Cooper , Hey , Lawrence, ^-c.) Though the crural ring is almost always small, yet in a few instances, in which the tumour is large, and of long standing, it be- comes very capacious, just as the opening often becomes, through which the inguinal hernia protrudes. Dr. Thomson, of Edin- burgh, Mr. Hey, and Mr. Lawrence, have related examples of this kind. The remarks already made, concerning the treatment of hernia, before having re- course to the knife, are all applicable to the present case, and need not be repeated. In attempting to reduce the femoral hernia by the taxis, the surgeon should recollect, how- ever, that relaxing Poupart’s ligament, and the femoral fascia, is of the higiiest conse- quence. Hence, the thigh should be bent, and rolled inwards. The pressure ought also to be first made downwards and back- wards, in order to push the swelling off Poupart’s ligament ; and afterward, the parts should be propelled upwards, so that they may return through the crural ring. OPERATION FOR THE FEMORAL, OR CRURAL HERNI A . Mr. A. Cooper says, “ the incision of the IIEKNIA* n integuments is to be begun an inch and a half above the crural arch, in a line with the middle of the tumour, and extended downwards to the centre ot the tumour be- low the arch. A second incision, nearly at right angles with the other, is next made, beginning from the middle of the inner side of the tumour, and extending it across to the outer side, so that the form of this double incision will be that of the letter I rever- sed.” The angular flaps are, of course, to be next dissected oft', and reflected. The making of two incisions, however, is not deemed necessary by the majority of surgeons ; and, in all the numerous opera- tions which I saw performed in St. Bartholo- mew’s Hospital, during a space of nearly fifteen years, a transverse wound was not found necessary. The division of the skin should begin about an inch above the crural ring, and be continued obliquely downwards and outwards. In this manner, we cut exactly over the place, where the incision of the stricture should be made. “ The first incision (says Mr. A. Cooper) exposes tbe superficial fascia, which is given off by the external oblique muscle, and which covers the anterior part of the hernial sac ; but, if the patient is thin, and the her- nia has not been long formed, this fascia escapes observation, as it is then slight and delicate, and adheres closely to the inner side of the skin. When this fascia is divi- ded, the tumour is so far exposed, that the circumscribed form of the hernia may be distinctly seen ; and a person not well ac- quainted with the anatomy of the parts, would readily suppose that the sac itself was now laid bare. This, however, is not the case, for it is still enveloped by a membrane, which is the fascia, that the hernial sac pushes before it, as it passes through the in- ner side of the crural sheath. This mem- brane, the fascia propria, is to be next divi- ded longitudinally from the neck to the fun- dus of the sac ; and if the subject is fat, an adipose membrane lies between it and the sac, from which it may be distinguished, by seeing the cellular membrane passing from its inner side to the surface of the sac. “ This is, in my opinion, the most diffi- cult part of the operation : for the fascia propria is very liable to be mistaken for the sac itself ; so that when it is divided, it is supposed that the sac is exposed, and the in- testine is laid bare ; following upon this idea, the stricture is divided in the outer part of the sac, and the intestine, still stran- gulated, is pushed, with the unopened sac, into the cavity of the abdomen. 11 The hernial sac being exposed, is to be next opened ; and, to divide it with safety, it is best to pinch up a small part of it be- tween the finger and thumb ; to move the thumb upon the finger, by which the intes- tine is distinctly felt, and may be separated from the inner side of the sac ; and then to cut into the sac, by placing the blade of the knife horizontally. Into this opening, a di- rector should be passed, and the sac opened from its fundus lo the crural sheath. (0/t, Crural and Umbilical Hernia.) Sometimes the content* of the hernia, thus exposed, admit of being returned, with- out the further use of the knife. When this object, however, cannot be readily done, the protruded parts should never sutler in- jury from repeated manual attempts ; and it is safest to divide the stricture at once. The merit of having first proposed the safest plan of cutting Poupart’s ligament, even before surgeons were aware of tbe parts which really form the strangulation, is assigned by Gimberrmi to Mr. B. Bell, who introduced his finger below Poupart’s liga- ment, between the ligament and the intes- tine, (an evident proof, says Gimbernat, that there was no strangulation there ;) he then made a very superficial incision from above downwards, into the thickest part of the ligament to its lower edge ; and, with- out rutting quite through it, he continued his incision about an inch. He rested the back of the scalpel upon his finger, which served as a guide to the instrument, and, at the same time, as a defence to the intestine. The incision, however, having been con- tinued for an inch, would, as Gimbernat re- marks, inevitably cut the internal edge of the crural arch. Now, cutting this, only for a few lines, gives sufficient room, for the easy reduction of the parts, and there is no necessity to touch the ligament, as it never occasions the strangulation. — ( Gimbernat V- 27.) Gimbernat’s method of dividing the stric- ture, in cases of femoral hernia;, is now fre- quently regarded as the safest and most ef- fectual. “ Introduce, alongthe internalsideof the intestine, a cannulated or grooved sound, with a blunt end, and a channel of sufficient depth. This is to be directed obliquely in wards, till it enter the crural ring, which will be known by the increased resistance ; as also when its point rests upon the branch of the os pubis. Then suspend the intro- duction ; and keeping the sound (with your left hand, if you are operating on the- right side, and v. v.) firmly resting upon the branch of the os pubis, so that its back shall be turned towards the intestine, and its can*l to th#symphysis pubis, introduce gent- ly with your other hand, into the groove of the sound, a bistoury, with a narrow blade and blunt end, till it enter the ring. Its en- try will be known, as before, by a little in- crease of resistance. Cautiously press the bistoury to the end ot the canal : and em- ploying your two hands at once, carry both instruments close along the branch to the body of the pubis, drawing them out at the same time. By this easy operation, you will divide the internal edge of the crural arch at its extremity, and within four or five lines of its duplieature ; the remainder continuing firmly attached, by the inferior band, or pil- lar, of which it is the continuation. This simple incision being thus made, without the smallest danger, the internal border of the arch, which forms the strangulation, will be considerably relaxed, and the parts will be HERNIA. 3'S reduced with the greatest ease.” ( Gimber - not , p. 45, 45.) Mr. A. Cooper recommends the stricture t'o be divided “ obliquely inwards and up- wards, at right angles to the crural arch.’' After advising us to open the sac of a fe- moral hernia, with particular care, on ac- count of its being much thinner than that of a bubonocele, and (as might be added) on account of its seldom containing any fluid, and often having no omentum in it covering the intestine, Mr. Hey remarks, “ The stric- ture made upon the prolapsed pails is very great, as 1 have already observed; but if the tip of the huger can be introduced within the femoral ring, to guide the bubo- nocele knife, a small incision (for the ring is narrow) will be sufficient to set the parts at liberty. If the tip of the linger cannot he introduced at the proper place, a director with a deep groove must be used instead of the linger ; but I prefer the latter. Tne finger, or director, should not be introduced very near the great vessels ; but on that side of the intestine or omentum which is near- est to the symphysis of the ossa pubis. The incision may then be made directly upwards. The surgeon must take especial care to in- troduce his finger or director within that part where he finds the stricture to be the greatest, which, in this species of hernia, is the most interior part of the wound.” (P. 255.) Gimbernat’s mode is preferable to Mr. Key’s, because, were the operation done on a male, cutting directly upward would en- danger the spermatic cord. Mr. Lawrence has noticed, that “ an inci- sion oftiie most interior part of the stricture is free from all danger, in the ordinary course of the vessels. But that variety, in which the obturatrix artery, arising from the epigastric, runs along the inner margin of the sac, seems to preclude us from cutting even in this direction. Hesselbacn met with a remarkable instance of such irregularity in the origin and course of the obturatrix ar- tery in the body of a female, in whom there were two small crural hernias. On the right side, the epigastric and obturatrix arteries arose, by a common trunk, from the crural artery below- Poupart’s ligament. Vlliey soon separated from one another ; the epigastric taking its ordinary course upwards at the outer side of the neck of the hernial sac, while the obturatrix made a considerable turn, and ran transversely inwards over the strong fibres of the femoral ligament, and encircled the anterior and inner side of the neck of the hernia, whence it afterward proceeded obliquely downwards and out- wards, behind the horizontal branch of the os pubis, towards the obturator foramen. ( Hesselbach , p. 52.) A mode of operating has been lately proposed, ( Edinb . Med. and ISurg. Journal , Pol. 2, 205.) with a view of avoiding this danger. We are directed to make an incision through the aponeurosis of the external oblique muscle, just above the crural arch, and in a direction parallel to that part ; to introduce a director under the stricture from this opening, and to divide the tendon to the requisite extent, by means of a curved knife passed along the groove. ( Treatise on Ruptures, Edit. 3 ,p. 407 ) For reasons which Mr. Lawrence states, this plan is certainly not altogether eligible,- and, upon the whole, Gimbernat’s method of cutting the stricture is the safest. Monro computes that the obturator artery may arise from the epigastric, once in twenty-five or thirty subjects. But, allowing that it origi- nates more frequently, it then does not always deviate from its usual course aiong the outside of the sac. Mr. A. Cooper says : “ in ad cases, wnich i have myself dissected, where tins variety existed with crural her- nia, tne obturator has passed into the pelvis, on the outer side ot the neck of the sac, en- tirely out ot the reach of any danger of the knife.” (On Crural Hernia, p. 21.) Mr. Lawrence concludes, that the comparative number of instances, in winch it is found on the opposite side, cannot be more than one in twenty, and consequently if we admit, that the obturatrix artery arises from the epigastric once in five times, it wodld only be liable to be wounded once in a hundred operations. (P. 412, Edit. 3.) When the origin and course of the epigas- tric artery ditfV -r from what is common, this vessel, as Hesselbach remarks, sometimes passes inwards' along the horizontal branch of the os pubis, ere it ascends towards tiie rectus muscle; and when this variation exists in a case of femoral hernia, the artery does not pass over the outer side of the neck of the sac, but first under it, and then round its inner side. Hesselbach has seen only one instance of this irregularity of the epigastric artery in a female, and never in a male subject. (Ueberden Ur sprung, tyc. dcr Leisten-und Schenkelbriiciie , p. 6z.) The industrious Cloquet examined 260 bodies, for the purpose of estimating the average number of cases, in which the origin and course of the obturatrix artery are different from what is most common. He found, that when this artery and the epigas- tric arise by one common trunk, they some- times separate from each other above, and rarely below the upper opening of the crural canal. In the first case, the longer their common trunk is, the closer do they lie to Gimbernat’s ligament, and to the inner edge of the upper opening of the above canal. In the second case, the common trunk of these arteries arises within this canal, and the two vessels then return into the abdo- men. In ICO bodies, of which 87 were male, and 73 female, the obturatrix artery arose on both sides from the hypogastric, and only in 55, ot which 21 were male, and 35 female, did it originate on both sides from the epigastric. In 28, of which 15 were male, and 13 female, the obturatrix arose on one side from the hypogastric, and on the other from the epigastric. In 5 bodies, viz. 2 male, and 4 female, it originated from the crural. (See liecherclies Hnat.sur Its Her - nits, 4to. Paris.) If is observed by Professor Scarpa, (hat HERNIA. 3P “ 1 lie vouml ligament of the uterus, in pass- ing through the abdominal muscles, tollows precisely the same track as the spermatic cord. It is equally situated behind Poupart’s ligament, with the difference, that it does not become so distinct from the internal extremity of this ligament, as the spermatic cord does, because it has not so far to run, in order to get from that ligament to the in- guinal ring, the latter opening being situated lower in the female, than the male subject. The round ligament, like the spermatic cord, also crosses the epigastric artery, before reaching the inguinal ring. And as the crural hernia always begins at the internal and inferior angle of the arch of this name, as well in the male as the female, it follows, that, in the two sexes, the epigastric artery remains in its natural situation, and invaria- bly corresponds to the external side of the neck of the crural hernia 5 whilst the sper- matic cord, in men, and the round ligament, in women, pass over the extremity of the front of the neck of the hernial sac. In the operation for the crural hernia, in females, the incision of the neck of the hernial sac, and crural arch, when directed upward to- wards the linea alba, cannot wound the epigastric artery, which it is of the most consequence to avoid ; but it always divides, either totally or partially, the round liga- ment of the uterus, which cannot lead to any dangerous hemorrhage ; for, except in the period of pregnancy, the arteries of the round ligament are very small; they are almost obliterated in women advanced in years ; and in general, they are quite capil- lary in the extremity of the ligament ad- joining the ring. Hence, it cannot be surpri- sing, that so many crural hernia? have been successfully operated upon in women, by cutting the hernial sac and crural arch directly upw ard, while not a single instance can be cited of such an incision being made in man without mischief, although, in both sexes, the epigastric artery may have been avoided in operating by this process.” ( Scarpa , Trait 6 des Hermes, p. 240.) In operating for the crural hernia in males, Scarpa recommends us to follow a method, which he calls new, but which, in fact, is the same as that advised by Gimbernat. I have found (says Scarpa) that, in man, the neck of the hernial sac maybe divided with- out danger, by giving to the incision a di- rection exactly contrary to that which is practised in the female subject. After having opened the hernial sac, it is to be drawn outward by one of its sides suffi- ciently to allow the introduction of a small director between its neck and the strangula- ted intestine, the groove of the instrument being turned downwards towards the internal and inferior angle of the crural arch. A probe-pointed bistoury, the edge of which is also to be directed downwards towards the point of insertion of PouparVs ligament to the pubes, is to be pushed along the groove. By this means, the neck of the hernial sac will be divided its whole length, at its internal and in- ferior side, and PouparVs ligament mil be cut close to its attachment to the lop of the os pubis. The epigastric artery will certainly be avoided, because it ljes upon the oppo- site side of the hernial sac. As for the sper- matic cord, 1 have demonstrated, that it is situated on the forepart of the neck of the hernial sac ; consequently, it cannot be touched by an incision made from above dow nwards, whilst it is ■constantly cut in the ordinary method, since the knife is carried from beiow upwards. In the first case, this part may be the more easily avoided, as it lies at some distance from the internal and inferior angle of the crural arch. In fact, it is at this place that it quits, as we have seen, the edge of Foupart : s ligament, in order to ascend towards the inguinal ring. The incision that 1 propose (says Scarpa) not only has the advantage of slitting open the neck of the hernial sac its whole length, it also divides a part of the insertion of Pou- part’s ligament into the upper part of the os pubis, a thing that gently contributes to re- lax the crural arch, and facilitate the re- duction of the viscera ; of those, at least, which are not adherent to the sac.” ( Scarpa Op. cit. p. 235.) Although this accurate anatomist and sur- geon appears to be quite unacquainted with many ot the late valuable publications oa hernia, which have made their appearance in this country, it is curious to find, both in his account of the inguinal and crural her- nia, how strongly his doctrines and observa- tions tend to confirm every thing that has recently been insisted upon in modem works, respecting the place where the bubo- nocele first protrudes, its passing through a sort of canal before it comes out of the ab- dominal ring, the advantage of cutting in the crural hernia the internal and inferior angle of Poupart’s ligament, or, in other terms, that part of the ligament which was first particularly pointed out by Gimbernat, as causing the principal part of the strangu- lation, and about which so much has been said by Mr. A. Cooper, Mr. Hey, &,c. Hesselbach considers an incision through the outer side of the crural ring safer than one through Gimbernat’s ligament, and safer in women than men. In women, he recom mends the cut to be made through the mid- dle ol the forepart of the ring, nearly straight upvyards, or a little inclined inwards, in w hich mode the epigastric artery cannot be hurt, whether it lie at the outer, or inner side of the neck of the sac. In men, this in- cision, directed obliquely upwards and in- wards, he says, cannot be made, on account of the nearness of the spermatic cord • therefore, in the male subject, he advises cutting the inner side of the opening, that is to say, Gimbernat’s, or the femorai liga- ment directly inwards towards the symphy- sis of the os pubis. ( Ueber den Ur sprung t tyc. der Leisteti-und-Schenkelbr « che, p. 54.) YV hen the epigastric, or obturator, artery de- viates from its usual course, and surrounds the inner side of the neck of the hernia (which variety can never be ascertained n l above this aperture. The appearance of a hernia in very early infancy, Mr. Pott observes, will always make it probable that it is of ibis kind; but he was not correct in asserting, that in an adult, there is no reason for supposing his rupture to be of this sort, but Ins having been afflicted with it from his infancy ; and that there is no externa! mark, or character, whereby it can be certainly distinguished from one contained in a c immon hernial sac. fhis statement is erroneous, inasmuch as the hernia congenita is attended with an Impossibility of feeling the testis, which part in the common scrotal hernia is always dis- tinguishable under the fundus of the hernial sac. The hernia congenita, when returnable, tl ought, like ail other kinds of ruptures, to be reduced, and constantly kept up by a pro- per bandage; and when attended with symptoms of stricture, it requires the same chinn'gic assistance as the common her- nia."’ Mr. Pott notices, “that in very young children, a piece ol intestine, or omentum, may get preo.y low down in the sac, while the testicle is still in trie groin, or even within the abdomen. In this case, the appli- cation of a truss would lie highly iuipioper; for, in the latter, it might prevent the de- scent of the testicle from the belly into the scrotum , in the former, it must necessarily bruise and injure it, give a great deal of un- necessary pain, and can prove of no real use. Such bandage, therefore, ought never to be applied on a rupture in an infant un- less the testicle can be fairly felt in the scro- tum, after the gut or caul is replaced ; and when it can be so felt, a truss can never be put on too soon.” Many additional observations on the fore- going topic are contained in the 2d vol. of w>i. n o the First Lines of Surgery, for which reason I do not here expatiate upon it. Mr. Pott explains, that ati old rupture, originally con- genital is subject to a stricture, made by the sac itself, as well as to that produced by the abdominal ring, or. as might have been add- ed, to that caused by the inner opening of tlm inguinal canal. The fact lie noticed several times, both in the dead a d in the living. “ I have seen (says he) ictly deserve the epithet congenital, as they appear at l*irth The funis en Is in a sort of bag, containing some of the viscera, which pass out of the abdomen through an aperture in The situation of the navel The swelling is not covered with skin, so that the con- tents of the hernia can be seen through the thin distended covering of the cord. The disease is owing to a preternatural deficiency in the abdominal muscles, and the hope of cure must-be regulated by the size of the malformation, and quantity of viscera pro- truded. The plans of cure proposed, consist of the employment of a ligature, or of a bandage. The latter seems preferable, and was prac- tised by Mr. Hey, as follows : having redu- ced the intestine, he desired an assistant to bold the funis compressed sufficiently near the abdomen, to keep the bowel from re- turning into the hernial sac. “ I procured (says he) some plaster spread upon leather, cut into circular pieces, and laid upon one another in a conical form. This compress I placed upon the navel, after I had brought the skin on each side of the aperture into contact, and had laid one of the lip's a little over the other. I then put round the end . - abdomen a linen belt : and placed upon the naval, a thick, circular, quilted pad, formed about two inches from one extremity of the be it. “ This bandage kept the intestine securely within the abdomen, and was renewed occasionally, The f inis was separated abo t a. week afterbirth ; and at the expiration of a fortnight from that time, the aperture at. the navel was so far contracted, that the crying of the child, when the bandage Was removed, did not cause the least protrusion. I thought it proper, however, to continue the use of the bandage a little while longer. A Small substance, S ■ k e fungous flesh, pro- jected, after the funis had dropped off about half an inch from the bottom of that de- pression which the nave! forms. A dossil of lint spread with cerat. e lapide calaminari, and assisted by the pressure of the bandage, brought on a complete cicatrization."’ (P. 227.) This gentleman has related another exam- ple, in which the intestines were quite' un- covered and inflamed, the sac having burst in delivery The parts were reduced;, but the child died. (See also G. A Fried de Fcetu intestims plane nudis extra abdomen propen -• dentibus nalo. Argent. 17**0.) UMBILICAL HER SI A IN CHILDREN. The umbilical hernia, which is sometimes formed in the fetus, from causes difficult of explanation, takes place, in. other instances, at t’ne moment of delivery ; and then, as Sabatier remarks, should it be tied by mis- take, with the funis, death would be the con- sequence. Most frequently, however, it is not till the second, third, or fourth month after birth, that the disease occurs ; and the numerous cases collected by Desault prove that, of ten infants attacked with this hernia. nine become afflicted at the periods just mentioned. The umbilicus, still open, now begins to contract, so as to close the cicatrix, which soon forms an obstacle capable of prevent- ing a protrusion of the viscera. Sometimes, however, the repeated crying of the child propels the viscera through the opening, and thus the closure of the cicatrix of the navel is prevented. By degrees, the umbilical ring becomes more and more dilated, the quanti- ty of protruded bowel increases, and thus a tumour arises, which, from being of trivial size at first, at length attains the size of an egg, or large walnut, and presents itself with all the characteristic marks of a hernia. The presence of a piece of intestine and omentum in the tumour, keeps the umbilicus open, and opposes the continual tendency which it has to close. Such tendency, how - ever, being sometimes superior to the resist- ance of the protruded parts, forces them back info the abdomen, obliterates the open- ing through which they passed, and thus the spontaneous cure of the umbilical hernia in children is accomplished. Two cases illus- trative of this fact, are related by Bichat. ((Entires L'hir. de Desault, T. 2, p. 318 ) f'yature, however, does no* effect many su< h cures, and when the case is left to her alone, she not only fails in bringing about a radical cure, but gradually renders it impos- sible. In short, the propensity of the open- ing to lose diminishes, and is lost, as the sub- ject grows older. Thus, the umbilical hernia of children seems to be essentially different from that of adults, in the tendency of the aperture to contract. Hence the ease of affecting a radical cure in children, and the almost utter impossibility of doing so in adults. In the former, it is enough to keep the intestines from protruding, and the opening becomes of itself obliterated ; in the latter, the open- ing always remains, whether the bowels con- tinue in it or not. This indisposition of the aperture to contract in the adult, also fre- quently depends upon the protrusion not be- ing through the umbilical ring itself, but through a fissure in the vicinity of it, not endued with* the same natural tendency to close, which the umbilicus possesses in young subjects. In fact, it would appear from the observations of Scarpa, detailed in the 2d vol. o! the First bines of Surgery, that, unless a grown-up person lias the pro- trusion from infancy, it nevel* occurs exact- ly through the umbilical ring itself The means of curing the umbilical hernia of children, are of three kinds ; external ap- plications; compression ; and the ligature. The first are totally useless ; and as t hey occasion a waste of time, are improper. Compression, and the ligature, are the only rational plans. The former is the most modern ; the latter the most ancient treat- ment, as it is mentioned by Celsus. Desault tells us, that the design both of the ligature and compression is the same, viz. to prevent the lodgment of the protruded viscera in the opening of the umbilicus, and thus faci ' HERNIA. 45 litate the approximation of its sides. To accomplish this end, the ligature retrenches the hernial sac, and skin pushed betore it ; and, by the union of the cut parts, a cicatrix is produced which hinders the protrusion of the viscera. At the same time, the sides of the opening, obeying their natural tendency, compression closes the deficiency, or open- ing, in the p rietes of the abdomen, hinders the protrusion of the bowels, and keeps tiese parts from resisting the contraction of the sac. Desault remarks, that though compres- sion occasions no pain, it is irksome, during the great length of time its employment is necessary. The ligature (he says) produces momentary pain ; but it is not at all irksome, and it effects in a few days, what compres- sion, when successful, accomplishes in seve- ral months. In one plan, long continual at- tention is requisite, and if its employment be only for a sli 'rt time neglected, the pre- vious effect becomes almost destroyed. The other method alu ays accomplishes its object with certainty, independently of the crying of the child, and the care of its attendants. When compression is adopted, it is executed either by means of a flat compress applied to the opening, and which does not enter it, or else by means of some round or oval body, such as a ball of wax, a nutmeg, &c. adapted to the shape of the aperture, and, as Platner and Richter, (in his Treatise on Hernia) advise, continually kept within the opening. In the first case, Bichat argues, that if the bandage be exactly applied, the skin and sac will form a fold in the aperture of the navel, hinder its closure, and operate in the same manner, from without, inward, as the protruded intestines did from within outward In the second case, he observes, the foreign body, being depressed into and maintained in the opening, will occasion, notwithstanding what Richter says, the same inconveniences, and, in a more striking man- ner, similar consequences,. But, on the con- trary, when the !i ature is employed, the sac and skin of the tumour are removed, while the opening remains free, and nothing prevents its obliteration. In this method, the omentum can never protrude outward ; but, in the other, if the compression should ever be inexact, the parts slip out again, above or below, and the disorder prevails o>i one side of the useless application. The ligature is also commended as producing an adhesion of the sides of the opening, either to each other, or the adjacent parts. This adhesive process arises from the inflamma- tion excited, and occasions a degree of firm- ness, not producible by any other mode of cure. With respect to compression, Bichat as- serts that children, on whom it is employed, are miserably annoyed with it for years, while the ready success of the treatment with the ligature, is attested by a series of well-authenticated cures, which in Desault’s practice, amounted to the number of fifty. In the latter years of his practice, says Bi- chat, many persons were also seen bringing to' his public consultations their, children. which were immediately operated on with- out any preparation, carried home, and b roug'd the next, and every following day, to be dressed, till the cure was com- plete. The children of the poor may be cured in an hospital, with the ligature, in the space of a few days But, when compression is adopted, the parents are frequently put to repeated expense, as the bandage wears out ; and to additional loss from the time con- sumed in payin, die necessary attention. The ancients had different modes of ap- plying the ligature. One consisted in redu ing the parts, and afterward tying the in- teguments afid sac, without opening the lat- ter at all. In the other, an incision was made ir. the sac, either before or after tying it, for the purpose of being sure, that no piece of intestine was, and could become, strangulated in the ligature Celsus adopted the first plan ; Paulus iEgiueta preferred the second ; and he was imitated by Avicenna, Atbucasis, and Guy de Chauiiac. The first of these methods is less painful, and equally safe ; for, we soon become habituated to ascertaining, whether there is still any intestine in the sac, by rubbing the opposite sides of this bag against each other. The other, which is unnecessarily cruel, in- creases the pain, without making the method at all more successful. Some of the old practitioners simply tied the base of the tu- mour ; others passed through it one, or two needles, armed with ligatures for the pur- pose of fixing such ligatures in a better man- ner, and, for this purpose, they even some- times made a circular incision. Desault’s method, which much resembled that of Saviard’, was simple, and is described by Bichat as attended with little pain. The child must be placed on its back, with its thighs a little bent, and its head inclined towards the chest. The surgeon is to re- duce the protruded parts, and to hold them so with bis finger, at the same time that he raises the hernial sac, and rubs its sides be- tween his fingers, so as to be sure that there is nothing contained in it. Being certain, that the parts which he lifts up, are only the skin and sac, he is to direct an assistant to surround their base several t^mes with a waxed ligature, of middling size, each turn being tied with a double knot in such a man- ner as only to occasion liple pain. The tu- mour, thus tied, is to be covered with lint, which is to be supported with one or two compresses, and a circular bandage, secu- red With a sea pulary. By the following day a slight swell: i has commonly taken place in the constricted parts. On the second, or third day, the parts shrink, and then the ligature becomes loose, so that a fresh one must now be applied in the same manner as the first, taking care to draw it a little more tightly. The sensibility of the parts, increased by the inflammation, which the constriction of the ligature has already produced, usually renders th s second ligature more painful After the operation, the same pressings, as^at first, are to be ap. 46 1IEKNIA. plied. The tumour soon becomes discolour- ed, livid, and smaller. A third ligature, put on in the same way as the preceding ones, entirely obstructs the circulation in it. The part turns black and flaccid, and commonly falls off oi the eighth orter.lh day. A small ulcer is left, which, being properly dn-ssed, very soon heals, and leaves a cicatrix suffi- ciently strong to resist the impulse occasion- ed by coughing, or other efforts of the abdo initial muscles. For two or three months, however, afterthe operation the child should Wear a circular bandage, in order to prevent, with still greater certainty, the vi cera from being propelled against the cicatrix, so as to interrupt the process of nature, which is now producing a gradual closure of the umbilical opening. Numerous cases might here be adduced, in confirmation of the above prac- tice ; but, several (nine) are already publish- ed in the Parisian Chirurgical Journal. But one may doubt, (says Sabatier) quo- ting the article in the journal, where Desault treats of the present disease, whether the infants got rid of the hernia, as it might have returned some time afterward. To this ob- servation, Bichat replies, that numerous facts remove the doubt ; for, several of the sub- jects were brought to Desault’s public con- sultation, for other diseases, a long while after they had been operated upon, and the great number of students, who examined them, all acknowledged, that the ring was completely obliterated, and there was no impulse of the viscera in coughing, sneezing, &c. Other children, in the knowledge of the surgeons of the H&tel-Dien, remained perfectly cured, and Bichat was acquainted with two young subjects on whom the oper ration had been performed four years, and they had had no relapse. In young infants the operation almost con- stantly answered ; but, in proportion as their age increased, it was tound to be less certain. Bichat relates three cases, v\ hich tend to prove, that success may be completely ob- tained at the age of a year and a half ; that the cure is difficult, when the child is four years old ; and impossible, when it is nine. (See CEuvres Chir. de Desault , par Bichat, T . 2, p. 315, fyc.) Mr. Pott notices the plan of curing the exomphalos with the ligature and expresses himself strongly against the practice in gene- ral. To adults the plan is not applicable, particularly when the tumour is large. Mr. Pott was decidedly in favour of compression, and he observes, that, in young subjects, and small herniae, a bandage, worn a proper time, generally proves a perfect cure. ( Vul . 2 .) Anxious that this work should be strictly impartial, I next proceed to relate what has been more recently urged against the em- ployment of the ligature for the cure of the umbilical hernia in children The incessant care that a bandage requires, either to keep it clean or make it always keep tip the proper degree of pressure, n ri- ders its employment difficult in the children of the poorer classes. Scarpa expresses his opinion, that “this was what induced De- sault to revive the Operation for the umbili- cal hernia by tire ligature, nearly such as is described by Celsus, an operation (continues Scarpa) which, a long while ainc> , and for good reasons, was altogether abandoned. Celsus has sufficientlv described the particu- lars of it : (Lib. 7, Cap. 14,) he states, that the tumour is sometimes to be mm ply lied, and that, in other instances, its base is to have a needle and double ligature introduced through it, in order that it may be embraced almost in the ••ame. way as a staphyloma is lied Bui among the causes which contra- indicate this operation, he mentions so many circumstances in relation to age, constitution, diseases of the skin, &c. that lie seems to consi- der thecases in which it may be practised with success as very few. The same reflections were made by several olher ancient surgical writers, especially by Fabricius ab Aquapen- dente Desault himself has put some restric- tions to the employment of the ligature, since he observes, with his usual candour, 1 hat this method docs not radically cure the umbilical herma of children, arrived at the age ol four year?; that it is indispensable, as Celsus inculcates, to employ a needle and double ligature, v\ hen the base of the tumour is very large ; and lastly, that even in the youngest children', a radical cure cannot be effected by die ligature, unless a methodical compression of the navel, by means of a bandage, be kept up immediately after the operation, and for two or three months It is perhaps to the omission of this last means, that a relapse is to be ascribed in several of the children operated upon by Desault. “ De- sault avoit remis en vigueur la ligature tom- b6e en ddsudtude. It s'abusoit sur sa valeur ; et il nest pas difficile d’en connoitre la cause. Tons les enfans qu'il opdroit d VH&tel-Dieu sortoienf gueris el n'y revenoient plus : on rtgardoit alors comme radicale une gnirison morneutanee .” (Riche rand , Nosographie Chir. T. 2 ,p. 456.) I have carefully watched (says Scarpa) the immediate effects, and the more or less remote consequences of tying the umbilical hernia, either simply or by means of a m edle and double ligature ; and, after a considerable number of such cases, I be- lieve I can assert, that this operation , how- soever performed , is not alway exempt from grave and sometimes dangerous accidents. / can also add, that it never procures a truly radical cure un'ess the cicatrix, occasioned by it in the umbilical region be submitted for some mouths to a methodical ancbuninterrupted compression. It is not so uncommon, as some surgeons pretend, to set arise after the applica- tion of the ligature , a fever attended with symptoms of most violent irritation, and acute sufferings, which cause incessant crying, and sometimes convulsions. The ulcer, which is produced by the detachment of the swelling, is ulv)uys very large and difficult to heal. Every now and then it becomes painful, and emits fungous granulations , even though dressed ivith dry applications. u Latterly, it has been explained by a cele- brated surgeon, (Palette, Manor, del' lusti-, HERNIA. 47 tuie , Tom. 2, Pur/ I.) that the umbilical vein and the suspensory ligament of the liver, be- ing included in the ligature ot the umbilical hernia, the inflammation which originates in these pans may, perhaps, in certain cases, be communicated to the liver, so a* to put the child’s life in great danger. W hen, in consequence of the ligature, symptoms ot violent irritation come on, they are ordina- rily attributed to certain individual circum- stances, such as extreme sensibility, or a par- ticular /Imposition to spasm Hence, it is believed, that they should be considered as exceptions, which do not exclude the gene- ral rule, and prove nothing against the utility of the operation. But how (says Scarpa) can the surgeon ascertain the existence or nonexistence of these individual dispositions in the children upon which he is to operate ? Assuredly those subjects, in which I have had occasion to notice the >bove accidents, en- joyed, before the operation, perfect health in < very respect “ Whatever process be adopted for tying the umbilical hernia, it is evident that the tumour can only bp constricted as far as a little way on this side of the aponeurotic ring of the umbilicus, whence it follows that the integuments must always remain promi- nent and relaxed for a certain extent, at the front and circumference of this opening. Also, after the separation of the strangulated portion, there necessarily remains, under the cicatrix, a portion of the hernial sac, and of the loose integuments W’hich covered it ; and as the cicatrix itself never acquires sufficient firmness to resist the impulse ot the viscera, which tend to insinuate themselves into the remains of (he hernial sac, the hernia sooner or later reappears, and, in a short time, be : comes larger than it was before the opera- tion. If the subject is a little girl, it may he apprehended, that the first pregnancy will eause a recurrence of the hernia ; for, it is known, that, during gestation, the external cicatrix of the umbilicus is considerably dis- tended, and much disposed to give way.” Pott has seen terrible accidents cau-ed by the rupture of the cicatrix a* the navel, du- ring pregnancy. (C. hirurg . Works, Vol. 2 , p. 169.) It is true that, according to this writer, this cicatrix was not the consequence of a hernia, but rather of an abscess in the umbi- lical region, which abscess had forme ly been opened with a bistoury ; yet, observes Scarpa, it would not be impossible to raise doubts upon this conjecture. Lastly, alter the separation of the tumour, there always remains, between (he aponeurotic ring ot (be navel and the integuments, a small cavity, formed by the neck of the hernial sac ; a cavity into which the viscera begin to insi- nuate themseives after the operation, so as to binder the complete contraction of the um- bilical ring. The demonstration of what I have advanced is, in some measure, to be found in ihe old method of operating for the inguinal hernia, not in a strangulated state, by (he ligature of the hernial sac and sperma- tic cord. Most of the hernia?, operated upon by (his barbarous process, were subject to relapses, because, in all probability , the cica- trix was noi sufficiently firm to resist the impulse of the viscera, w hich entered the remains of the hernial sac. In the same man- ner, after the common operation for (he strangulated inguinal hernia although the cicatrix is formed very near the ring, there is no piudent surgeon who does not advise the patient to wear a bandage the rest of his life, observation having prove > that the hernia is still liable t<> recur. “ The experience of several ages leaves no doubt, that compression alone is an ex- tremely efficacious method of radically curing the umbilical hernia of young sub- jects. It is attended with no risk, and, pro- vided it be executed with the requisite cau- tion, it is hardly ever necessary to continue it longer than two or thife mouths for the purpose of obtaining a complete cure. On the olher side, ii it be clearly proved, by all that J have been observing, that the ligature never accomplishes a perfect cure without compression, it is manifest, that it cannot be at all advantageous for the children of the poor, since a bandage cannot be dispensed with. Il may be said, that in general it does not shorten the treatment ; for, in the most successful cases, the ulcer caused by it is not healed in less than a month, and, in order to make the cure certain, an exact compression must afterward he kept up, by means of a bandage, two months longer. It has already been staled, that three months are ordinarih sufficient for obtaining a radi- cal cure by the mere employment of a tom- pres-ive bandage.” ( Scarpa , Traitt des Her- nies,p. 344 — 349.) In the Journal G6n&ral de Medecine, T. 41. 1811, M. Girard has published a memoir on the umbilical hernia of children, w hich was read to the Medical Society of Lyons in May, 1811, and the object of which was to recommend compression as an effectual means of cure. The arguments used were very similar to those adduced by Scarpa. In the course of the discussion, M. Cartier affirmed, that he had seen many children operated upon by Desault, who were not cured of their, herniae. The subject was afterward taken up by the Medical Society of Paris, and the result of the debate was, that the employment of the ligature ought to be rejected. 1. Be cause the cure ot umbilical herniae is often accomplished by nature alone. 2. Be- cause compression^ either alone or aided by tonic remedies, always succeeds. 3. Be- cause (he operai ion of the ligature deserves the triple reproach of being painful, and not free from danger, if unfortunately a piece of intestine should chance to be included in the ligature ; of not succeeding in general, except with the as'istance of compression,* and of being sometimes uselessly practiced, a- De- sault himself give> us instances of. Accord- ing to M. Cayol. the insufficiency of the liga- ture was lung since acknowledged by 8aba tier, Lassus, Richerand, fee, . 48 HERNIA. UMBILICAL HERNIA IN ADULT SUBJECTS. This case is to be trailed on the princi lies common to nil ruptures. When reduci- )le., the. parts should be kept up with a band- age or truss; which plan howev in grown- up persons- dFords no hope ol a radical cure. Mr. Hey has described some very good trusses for the exornphalos, which are appli- cable 'o children, when compression is pre- ferred, as well as to -»duh -ubp o s Om was invented by the la:e Mr. Marrison. an ingeni- ous mechanic at Leeds. “ It consists of two pieces of thin elastic steel, which surround the sides of the abdo- men, and nearly in et behind. At their an- terior extremity they form conjointly an oval ring, to one side of which is fastened a spring of steel ol the form (-presented. At the end of this sprit)" is placed the pad or bol der ( iiat presses upon die hernia. By the elasticity of this spring the hernia is repressed in every position of the body, a d is thereby retained constantly Within the abdomen. A piece of calico or jean is fastened to each side of the oval ring, .having a continued loop at its edge, th'ough which a piece of tape is put, that may be tied behind the bodv . This contrivance helps to preserve the in- strument steady in itspropei situation. (Prac- tical Obs. in Surgery, p. 231.) And, i . the second edition of the preceding work, ano- ther truss for the exomphalos is described, the invention of Mr. England, of Leeds, but as some account is given of this instrument, with an engraving, in the 2d. vol.of the First Lines of Surgery, l shall not here repeat the description. When the exomphalos i > irreducible, and large, the tumour must be supported with bandages. e ' It is observed by Scarpa, t hat the umbi- lical hernia, arid those of the !i tea dii*, are less subjeetto be .strangulated than die ingui- nal and femora! hernia ; but tha:, when they are unfortunately atfe. ed with strangulation', the symptoms are more intense, and gan- grene comes on more rapidly, than in every other species of rupture. If the operation be performed, the event is frequently unfavour- able, because it is generally done too late. This practical fact is proved by 1 he experi- ence of the most celebrated surgeons of. every age. “ II est certain (.says Din i ) que de cette operation il en peril plus qu'il n'en re- chappe ” ( Cours d' Operations, p. 98, Ed. 1777, avec les notes de la Faye.) He also adds, that they who have die misfortune to be afflicted with an exomplialos, should ra- ther dispense with (heir shirt than a bandage. Heister says nearl\ the same thing. (Insti- iut. Chirurg. T. 2, Cap 94.) When the omentum alo >e is strangulated in the exomphalos, or hernia of the liuea alba, observation proves, that the symptoms are not less intense, than when the intestine is also incarcerated. There is this dill'-rcnce, however, that when the omentum alone is strangulated, only nausea occurs, and, if vo- miting should likewise lake place, it is less frequent and violent them when the bowel itself is strangulated. In the first case, the stools are hardly ever entirely suppressed. The proximity of the stomach is, no doubt, t lie reason v\ hy the strangulation of the omentum, in the umbilical hernia, ccasioris far more inten -e symptoms ol : ympathetic ir- lation than the strangulation ol the same vis- cus ;:i die inguinal or crural hernia. Here the operation is not only always ne- cessary, but urgently required. It is not materially different from that which is prac- tised for the strangulated inguinal and crural hernia} ; but . in general, it demands'greater cirmm.ipee.tioi , on account ol the connexion or intimate adhesions, which In quenlly exist between die integuments and hernial sac, and also the adhesions which often prevail between the latter part and the omentum winch it contains. The situation of the in- testine, which is frequently covered by and enveloped in the omentum, is another cir- cumstance deserving earnest attention. ( Scarpa , Trait 6 des Hernies, p. 361, 362.) M:\ Potl is not such an advocate as Scar- pa for the early performance of the opera- tion in cases of exomphalos : “ The umbili- cal, like the inguinai hernia, becomes the subject of chirurgie operation, when the parts are reducible by the hand only, and are so bound as to produce bad symptoms. But though 1 have in the inguinal and scro- tal hernia advised the early use of the knife, I cannot press it so much in this ; the suc- cess of it is very rare, and 1 should make it the last remedy Indeed, I am much incli- ned to believe that the bad symptoms v\ hich attend these cases are most frequently owing t disorders in the intestinal canal, and not .-<> often to a stricture made on it at the navel, as is supposed. 1 do not say that the latter does rot sometimes happen ; it certainly does ; b it it is often believed to be the case when -t is not. “ When the operation becomes necessa- ry, it consists in dividing the skin and her- nia! sac, in Luch manner as shall set the in- testine free from stricture, and enable the surgeon t<» return it into the abdomen. ( Pott on Ruptures.) The rest of the conduct of »he surgeon is to be regulated by the usual principles. The division of the stricture is properly recommended to be made directly upward, in the course of the liuea alba. In consequence of the great fatality of the usual operation for the exomphalos, l think the plan suggested, and successfully practised by Mr. A. Cooper in two instan- ct s, should always be ado ted, whenever the tumour is lar .e, and free from gangrene ; a plan, that has also received the high sanc- tion of that distinguished anatomist and sur- geon, Professor Scarpa. ( Trait6 dcs Her- nie , p. 362.) Perhaps 1 might safely add, that, when the parts admit of being reduced, without laying open the sac, this method should always be preferred. It consists in making an incision just sufficient to divide the stricture, without opening the sac at all, or at all events, no more of it, than is inevi- table. HERNIA. In umbilical hernia?, ot’ not a large size, Mr. C. recommends the following plan of operating : “ As the opening into the abdo- men is placed towards the upper part of the tumour, l began the incision a little below it, that is, at the middle of the swelling, and ex- tended it to its lowest part. 1 then made a second incision at the upper part of the first, and at right angles with it, so that the double incision w as in the form of the letter T, the top of which Crossed the middle of the tumour. The integuments being thus divided, the angles of the incision were turned down, which exposed a considerable portion of the hernial sac. This being then carefully opened, the finger was passed be- low' the intestines to the orifice of the sac at the umbilicus, and the probe-pointed bis- toury being introduced upon it, I directed it into the opening at the navel, and divided the linea alba downwards, to the requisite degree, instead of upwards, as in the former operation. When the omentum and intes- tine are returned, the portion of integument and sac, which is left, falls over the opening at the umbilicus, covers it, and unites to its edge, and thus lessens the risk of the peri- tonasal inflammation, by more readily clo- sing the wound.” (Oil Crural and Umbili- cal Hernia.) LESS FREQUENT KINDS OF HERNIA. The ventral hernia, described by Oelsus, is not common ; it may appear at almost any point of the anterior part of the belly, but i -3 most frequently found between the recti muscles. The portion of intestine, he. is always contained in a sac, made by the pro- trusion of the peritonaeum. Mr. A. Cooper imputes the disease to the dilatation of the natural foramina for the transmission of vessels, to congenital deficiencies, lacera- tions, and wounds of the abdominal mus- cles, or their tendons. In small ventral her- nia?, a second fascia is found- beneath the superficial one ; but, in large cases, tlie lat- ter is the only one covering the sac. Hernia? in tiie course of the linea alba sometimes occur so near the umbilicus, that they are liable to be mistaken for true um- bilical ruptures. They may take place either above, or below the navel. The first 1 case, however, is more frequent than the second, and the following is the reason of this circumstance according to the opinion of Scarpa. u The upper half of the linea alba, that which extends from the ensiform cartilage to the umbilicus, is naturally broader and weaker, than the lower half, the recti muscles coming nearer and nearer together, as they descend from the navel to the pubes. (Scarpa, Traill des Her nits, p. 333.) The hernial sac of ruptures at the upper part of the linea aiba may contain a noose of intestine, and a piece of the omentum, though in most cases, a portion of the latter membrane alone forms the contents. In some subjects, the linea alha is so disposed ! to give way, that several hernia; are obser- 1 Vol. If. ' 7 lit ved to be formed successively in the inter- space between the ensiform cartilage and the umbilicus. “ With respect to the small hernia (says Scarpa,) w hich is considered as formed by the stomach, and concerning which Iloin and Garengeot have written so much (with- out either of them having related, at least to my knowledge, a single example proved by dissection,) it is at least unproved, that it was exclusively formed by this viscus. 1 do not see, why the other viscera, particu- larly the omentum and transverse colon, might not also contribute to it. In my judgment, it only differs from other hernia; of the linea alba, in being situated on the left side of the ensiform cartilage, a situa- tion that must materially influence the symptoms of the case. In fact, whatever may be the viscera, which form it, a sympa- thetic irritation of the stomach is occasion- ed, tliat is much more intense, than that which ordinarily accompanies umbilical hernia?, those of the lower part of the linea alba, or, in short, all other hernia;, which are more remote from the stomach.” (Op, cit. p. 334.) ! he following are said to be the circum- stances, by which the umbilical hernia, and that which occurs in the linea alba near the navel, may be discriminated. The first, w hether in the infant or the adult, has a roundish neck or pedicle, at the circumference of which the aponeurotic edge of the umbilical ring can be felt. Whatever may be its size, its body always retains nearly a spherical shape. Neither at its apex, or its sides, is any wrinkling of the skin, or any thing like the cicatrix ot the navel, distinguishable. In some points of the surface of the tumour, the skin is merely somew'hat paler and thinner, than elsewhere. On the contrary, the hernia of the linea alba has a neck, or pedicle, of an oval form, like the fissure through W'hich it is protru- ded. The body of the tumour is also con- stantly oval. If the finger be pressed deep- ly round its neck, the edges of the opening in the linea alba can be felt ; and, if the hernia be situated very near the umbilical ring, the cicatrix of the navel may be ob- served upon one side of it, which cicatrix retains its rugosity, mid all its natural ap- pearance ; a certain indication, that the vis- cera are not protruded through the umbili- cal ring. (Scarpa, Traill des Hernies, p. 33b.) The distinction which Scarpa has estab- lished between the umbilical hernia?, proper- ly so called, and those of the linea alba, is not useless in regard to practice. Indeed, w hen the latter are left to themselves, they make much slower m’ogress, than the form- er. On account of their smallness, they frequently escape notice, particularly in fat persons, and, wdien situated at the side of the ensiform cartilage. They occasion, however, complaints of the stomach, habitu- al colics, especially after meals ; and, un- fortunately for the patient, he may be tor- mented a very long time by these indispa- HERNIA. AO sitions, before the true cause of them is dis- covered. The umbilical hernia may be known, from the earliest period of its formation, by the alteration which it produces in the cicatrix of the navel, and the rapidity of its increase. In other respects, these two kinds of her- niffi demand the same means of cure ; but those of the linea alba, cceteris paribus , are more difficult to cure, than ruptures at the umbilicus. This is probably owing to the natural tendency, which the umbilicial ring has to close, when tiie hernia is kept well reduced, whilst accidental openings in the linea alba have not the same advantage. ( Scarpa , p. 340.) Wnen a common ventral hernia is redu- ced, it should be kept in its place by means of a bandage or truss. When strangulated, it admits, more frequently than most other cases, of being relieved by medical treat- ment. If attended with stricture, which cannot otherwise be relieved, that stricture must be carefully divided. Mr. A. Cooper recommends the valvular incision, and the dilatation to be made, either upward or downward, according to the relative situa- tion of the tumour and epigastric artery, which crosses the lower part of the linea semilunaris. Pudendal Hernia . — This is the name as- signed by Mr A. Cooper, to the hernia which descends between the vagina and ra- mus ischii, and forms an oblong tumour in the labium, traceable w ithin the pelvis, as far as the os uteri. He thinks, that this case has sometimes been mistaken for a hernia of the foramen ovale. When reducible, a common female bandage, or the truss used for a prolapsus ani, should be w r orn. A pes- sary, unless very large, could not well keep the parts from descending, as the protru- sion happens so far from the vagina. Mr. A. Cooper is of opinion, that, w hen strangu- lated, this hernia, in consequence of the yielding nature of the parts, may generally be reduced, by pressing them with gentle and regular force, against the inner side of the branch of the ischium. If not, the warm bath, bleeding, and tobacco clysters are ad- vised. Were an operation indispensable, the incision should be made in the labium, the lower part of the sac carefully opened, and, with a concealed bistoury, directed by the finger, in the vagina, the stricture should be cut directly inw r ard, tow r ards the vagina. The bladder should be emptied, both before the manual attempts at reduction and the operation. (On Crural Hernia , fyc. p. 64.) Paginal Hernia . — A tumour occurs within the os externum. It is elastic, but not pain- ful. When compressed, it readily recedes, but is reproduced by coughing, or even without it when the pressure is removed. The inconveniences produced are an ina- bility to undergo much exercise or exertion ; for, every effort of this sort brings on a sense of bearing down. The vaginal hernia pro- trudes in the space, left between the uterus and rectum. This space is bounded below by the peri ton senna, whieh membrane is forced downwards towards the perinamm ; but, being unable to protrude further in that direction, is pushed towards the back part of the vagina. In one case Mr. A. Cooper advised the use of a pessary, but the plan was neglected. Probably, these cases are always intestinal. Some herniae protrude at the anterior part of the vagina. (si. Cooper on Crural Her- nia, fyc. p. 65, 66.) Perinatal Hernia . — In men, the parts pro- trude betw een the bladder and rectum ; in women, between the rectum and vagina. The hernia does not project, so as to form an external tumour, and, in men, its exist- ence can only be distinguished by examin- ing in the rectum. In women, it may be detected both from this part, and the va- gina. In case of strangulation, perhaps, this hernia might be reduced by pressure from within the rectum. An interesting case of perinaeal hernia, which took place from the peritonaeum being wounded with the gor- get in lithotomy, is related by Mr. Brom- field ; Chirurgical Obs. p. 264. The reducible perinaeal hernia in wmmen may be kept from descending, by means of a large pessary. Both this kind of rupture and the vaginal may prove very dangerous in cases of pregnancy. (See Smellie’s Mid- wifery, Case 5.) Thyroideal Hernia, or Hernia Foraminis Ovale. In the anterior and upper part of the obturator ligament, there is an opening, through which the obturator artery, vein, and nerve proceed, and through which, oc- casionally, a piece of omentum, or intestine is protruded, covered with a part of the peritonaeum, wdiich constitutes the hernial sac. In the case which Mr. A. Cooper met with, the hernia descended above the obtu- ratores muscles. The os pubis w as in front of the neck of the sac ; three-fourths of it were surrounded by the obturatorligament ; and the fundus of the sac lay beneath the pectineus and adductor brevis muscles. The obturator nerve and artery were situa- ted behind the neck of the sac, a little to- wards its inner side. This species of hernia can only form an outward tumour, when very large. Garengeot, however, met with an instance, in which there was not only a swelling, but, one attended with symptoms of strangulation : he reduced the hernia, which went up with a guggling noise ; the symptoms .were stopped, and stools soon followed. The hernia of the foramen ovale, when reducible, must be kept up w ith a suitable truss ; and if it were strangulated, and not capable of relief from the usual means, an operation would be requisite, though at- tended with difficulties. T he division of the obturator ligament and mouth of the sac should be made inwards, to avoid the obtu- rator artery. If this vessel, however, were to arise in common with the epigastric ar- tery, it. would be exposed to injury bv fo! HERMA lowing; this plan. (See Garengeol in Mini, de VAcad. de Cfiir. T. 1 ; A. Cooper on Cru- ral Hernia, fyc. p. 70 : and First Lines of Sur- gery, Vol. 2, p. 80. 4'C.) < yslocele. — As Mr. Pott observes, “ The urinary bladder is also liable to be thrust forth from its proper situation, either through the opening in the oblique muscle, like the inguinal hernia, or under Poupart’s liga- ment, in the same manner as the femoral. “ This is not a very frequent species of hernia, but does happen, and has as plain and determined a character, as any other. “ it has been mentioned by Bartholin, T. Dorn. Sala, Platerus, Bonetus, Ruysch, Petit, Mery, Verdier, & c. In one of the histories given by the latter, the urachus, and imper- vious umbilical artery on the left side, were drawn through the tendon into the scrotum, with the bladder; in another he found four calculi. “ Ruysch gives an account of one com- plicated with a mortified bubonocele. Petit says, he felt several calculi in one, which were afterward discharged through the ure- thra. ^See also J. G. F. Jahn de insoht ® Calculi Ingentis per Scrotum exclusiotie. IVit- tenberg. 1750.) “ Bartholin speaks of T. Dorn. Sala as the first discoverer of the disease, and quotes a case from him, in which the patient had all the symptoms of a stone in his bladder ; the stone could never be felt by the sound, but was found in the bladder (which had passed into the groin) after death. “ As the bladder is only covered in part by the peritonaeum, and must insinuate itself between that membrane and the oblique muscle, in order to pass the opening in the tendon, it is plain that the hernia cystica can have no sac, and that when complica- ted with a bubonocele, that portion of the bladder which forms the cystic hernia must lie between the intestinal hernia and the spermatic cord, that is, the intestinal hernia must be anterior to the cystic. “ A cystic hernia may, indeed, be the cause of an intestinal one ; for when so much of the bladder has passed the ring, as to drag in the upper and hinder part of it, the peritonaeum which covers that part must follow, and by that means a sac be formed for the reception of a portion of gut or caul. Hence the diiferent situation of the two herniae in the same subject “ While recent, this kind of hernia is easily reducible, and may, like the others, be kept within by a proper bandage ; but when it is of any date, or has arrived to any consider- able size, the urine cannot be discharged, without lifting up, and compressing the scrotum ; the outer surface of the bladder is now become adherent to the cellular mem- brane, and the patient must be contented with a suspensory bag. “ In case of complication with a bubono- cele, it the operation becomes necessary, great care must be taken not to open the bladder instead of the sac, to which it will always be found to be posterior. And it may also sometimes by the inattentive be 51 mistaken for a hydrocele, and by being treated as such, may be the occasion of great or even fatal mischief.” (Vol. 2.) The cystocele is always easily distinguish- able by the regular diminution of the swell- ing, whenever the patient makes water. Verdier and Sharp have accurately de- scribed the cystocle. Pott has ottered two cases, which fell under his observation ; Vol. 3. Pipelet le Jeune mentions a cystic hernia in perinteo, and several cases of its occurrence in the female ; Acad, de Cliir. T. 4. Pott cut into one cystocele, by mis- take. Mention is made (Edinb. Snrg. Jour. Vol. 4, p. 512.) of a cystic hernia, which protruded between the origins of the leva- tor ani, and obturator internus muscles ; the tumour made its appearance in the pu- dendum of an old woman. Much additional information respecting the cystocele, and its various forms, is contained in the second volume of the First Lines of Surgeiy, p. 49, be., accompanied with references to all the most interesting writers on the subject. An instance of protrusion of the bladder through a wound, caused by a bullock’s horn, is re- corded by Larrey. (Mem. de Cliir. Mil. T. 4, p. 289.) Ischiatic Hernia. — This disease is very- rare. A case, however, which was strangu- lated, and undiscovered till after death, is related in Mr. A. Cooper’s second pait of his work on hernia. It was communicated by Dr. Jones, so celebrated for his book on hemorrhage. The disease happened in a young man, aged 27. On opening the abdo- men. the ileum was found to have descend- ed on the right side of the rectum into the pelvis, and a fold of it was protruded into a small sac, which passed out of the pelvis at the ischiatic notch. The intestine was ad- herent to the sac at two points: the stran- gulated part, and about three inches on each, side, were very black. The intestines to- wards the stomach were very much distend- ed with air, and here and there, had a livid spot on them. A dark spot was even found on the stomach itself just above the pylorus. The colon was exceedingly contracted as far as its sigmoid flexure. A small orifice was found in the side of the pelvis, in front of, but a little above the sciatic nerve, and on the forepart of the pyriformis muscle. The sac lay under the gluttons maximus muscle, and* its orifice was before the inter- nal iliac artery, below the obturator artery, but above the vein. Mr. A Cooper remarks, that a reducible case might be kept up with a spring truss, and that if an operation were requisite, the orifice of the sac should be dilated directly forwards. (On Crural Her- nia,\c.p. 73.) For a further account of the ischiatic hernia, and references to the most interesting works on the subject, see First Lines of Surgery , Vol. 2, p. 84, fyc. Phrenic Hernia.— The abdominal visceri are occasionally protruded through the dia- phragm, either through some of the natural apertures in this muscle, or deficiencies, or wounds, and lacerations in it. The second kind of case is the most frequent: Morgagni u. of u. ua 62 hernia. furnishes an instance of the fust. Two cases, related by Dr. Macauley in Med. Obs. and Jnq. Vol. I, two more detailed in the Medi- cal Records and Researches, and two others published by Mr. A. Cooper, are instances of the second sort : and another case has been lately recorded by the latter gentle- man, affording an example of the third kind. A laceration of the diaphragm by fractured ribs, has produced a hernia. A case of this kind was dissected by Mr. Travers* at Guy’s Hospital. (Med. Ckir. Trans Vol. 0, p. 375.) In this last volume, may also be found the particulars of an interesting example, in which a considerable part of the large cur- vature of the stomach was protruded through a fissure of the diaphragm. The accident was unattended with any fracture of the ribs, and was caused by the upsetting of a stage coach, on which the patient was an outside passenger. Before death, he vomit- ed up a large quantity cf blood, and a small semicircular aperture was discovered on dissection in the lower part of t lie strangu- lated portion of the stomach. (P. 378, 379.) See also B. Stehelin, Tentamen Med. quod vemriculum, qui in Ihoracem migraveral , SfC. describit, 1721 ; (in Hallerii Disp. Anal. 6, 675.) Hildanus, Parc, Petit, Sehenck, Spc. also mention cases of phrenic hernia. The disease is quite out of the reach of art. Mesenteric Hertua. — If one of the layers of the mesentery be torn by a blow, w bile the other remains in its natural state, the in- testines may insinuate themselves into the aperture, and form a kind of hernia. The same consequence may result from a natu- ral deficiency in one of these layers. Mr. A, Cooper records a case, in which ail the small intestines, except the duodenum, were thus circumstanced. The symptoms during life were unknown. (On Crural Hernia, tyc. V - 82.) Mesocolic Hernia. — So named by Mr. A. Cooper, when the bowels glide between tiie layers of the mesocolon. A specimen of this disease is preserved at St. Thomas's Hospital. Every surgeon should be aware, that the intestines may be strangulated within the abdomen from the following causes : 1 Apertures in the omentum, mesentery, or mesocolon, through which the intestine protrudes. 2. Adhesions, leaving an aper- ture, in which a piece of intestine becomes confined 3. Membranous hands at the mouths of hernial sacs, which becoming elongated, by the frequent protrusion and return of the viscera, surround the intestine, so as to strangulate them within the abdo- men, when returned from the sac. (See A. Cooper on Crural Hernia, ..Tc. p. 85.) Pott remarks, that “ Ruysch gives an ac- count of an impregnated uterus being found on the outside of the abdominal opening ; and so do Hildanus and Seunertus. Ruysch also gives an account of an entire spleen having passed the tendon of the oblique muscle. And 1 have myself seen the ovaria removed by incision, after they had been gome months in the groin.” (Vol. 2.) More particulars respecting all the less frequent kinds of hernia are given in the second vo- lume of the First Lines of Surgery. Franco , Traiti des He rules, fyc. 8 vo., Lyon, 1561 : Lud. von Hammen, De Herniis , 12mo., Lugd. 1581. M alack- Geiger, Kelegraphia, sive De- scriplio Herniarurn, cum carundem curatio- nibus, lam Medicis, quam Ckirurgicis, 12 mo., Monackii, 1631 ; Ant. Le Quin, Le Chirur- gicn Herniaire, \2mo., Paris, 1697. J At Ire, Observation sur ant JVuuvelle Espece de Her- nie, Mini, de l' Acad, des Sciences; 1700. Mery, in Ike same work; 1701. Litlre, sur une Hernie Rare; same work; 1 7 Id. Mau- chart de Hernia incarcerata nova encheiresi extricatd, Tubing. 1722. Heister, Instil. Chi- rurg. el De Hernia Incarcerata Suppu- rala non semper tethali. Vogel, Abhandlung alter Arlen der Brucke ; Lcipz. 1738. Pey- ronie, Observations, fyc. sur la Cure des Her- nics avec Gangrene; Mem de l' Acad, de Ckir. T. 1. Gunz, Observalionum Anatomico- Ckirurgicarum de Herniis lib dies; Lips. 17-14; el Prolusio Invdatoria in qua de Eulero-Epiplocele ugebat, Lips. 1746. P. Kirkschbaum, De Hernia Venlriculi , Argent. 1749. P. une ) sur les Hernies de la Vessie, el de I’Estomac Acad, de Ckir. Tom. 4. Voter de Lien is Prolapsione , 1746. M. G. Pfannius , De Entero- Oscheo- cele antiqua, restitntione sacci herniosi f clicilcr HERNIA. 53 Nevada, absque brachtrio et sccfionc curata. die Ursache , fyc. dtr Hr ache am Bauchen and Erlangee, 1748 Peyronie sur un Strangle- Hecken, ausser der Mabel und Leistengegend. menl de I'intestin, cause in terieurcmenl }>ar 8vo. Frankof. 181 1 . B. G. Schreger, Versuche V adhArenct de (.'epiploon au-dessus de Van - Chirargische , T. 1 , p. 149, tjc. Versuche zur neau, Mem. de VAcad. de i hir. T. 1. Tenon VerMlkommung der Herniotomie, 8vo JYarn- in dead, des Sciences, 1764. A. G. Zimmer, berg, lsl I. Also B. 2, Ueber einige Hernien Hcrninrum communia Allribula el Parlitio, ausser der Mabel und Leistengegend. v. 155. 4lo., Gotl. 1754 Call, sen, System Chirurg. 8r o. Murnberg, 1818. F. L. ^ Trusiedl Dc hodiernce, pars posterior. Richter Von den Extensionis in Svlrendis Her niis Cruralibus Brnchen, in 2 Vvls 1778, 1779 or the French incarceratis pree incisione p ret dunlin 4lo. transl. by Rougtmonl, 4 to., Bonn, 1788. Also Herol. 1616/A. C. He. setback, Die. Sicherste liichler's Bibliothck, and Anfang. der IV un- Art des Bruchschriittes in der Leisic, 4to. darzn. B. Ph. Waefclaerts, De Herniis ea- Bamb. et Warzb. 1»19. B. G. Seiler, Ob- rumque divisio , to creep.) Nothing could be more confused, and un- defined, than the idea conveyed by the term herpes , as generally employed by medical men before the last few years. In fact, nu- merous cutaneous diseases, of the most op- posite kinds, but which had a tendency to creep, or spread slowly, were designated, as specimens of herpes. Thus, when I first entered the profession, it was common tor some of the most eminent surgeons in Lou- don frequently to call noli me tangere, or lupus, herpes of the nose ; and to apply the same term to tinea capitis, or the porrigo favosa. Happily, this vague mode of regarding dis- eases of the skin is beginning to give way to the judicious distinctions proposed by the late Dr. Willan, and so ably perfected by Dr. Bateman. The appellation, herpes, is limited by these physicians. “ to a vesicular disease, which, in most of its forms, passes through a regular course of increase, maturation, and decline, and terminates in about ten, twelve, or fourteen days. The vesicles arise in dis- tinct, but irregular clusters, which commonly appear in quick succession, and they ate set near together, upon an inflamed base, which extends a little way beyond the margin of each cluster. The eruption is preceded, when it is extensive, by considerable constitutional disorder, and is accompanied with a sensa- tion of heat and tingling, sometimes with severe deep-seated pain in the parts affected. The lymph of the vesicles, which is at first clearand colourless, becomes gradually milky and opaque, and ultimately concretes into scabs : but in some cases, a copious discharge of it lakes place, and tedious ulcerations en- sue. The disorder is not contagious in any of its forms.’' (See Bateman's Practical Synopsis of Cutaneous Diseases, p. 221, 222, Edit. 3) This author notices six species of the complaint: viz. herpes phlyctaenodes ; herpes zoster; herpes circinatus; herpes labialis; herpes praeputialis ; and herpes iri9. As most of these cases more properly be- long to the physician, than surgeon, I shall briefly describe three of them. According to Dr. Bateman, the Herpes Zoster, or shingles, is mostly preceded for two or three days, by languor, and loss of appetite, rigours, headacb, 'sickness, and t a fre- quent pulse, together with a scalding heat, and tingling in the skin, and shooting pains through the chest and epigastrium. Some- times, however, the precursory febrile symp- toms are very slight. Upon some part of the trunk, several red patches occur, of an irregular form, at a little distance from each other, upon each of which, numerous small elevations appear clustered together. These, if examined minutely, are found to be dis- tinctly vesicular, and in the course of twenty- four hours, they enlarge to the size of small pearls, and are perfectly transparent, being filled with a limpid fluid. For three or four days, fresh clusters continue to arise, always extending themselves nearly in a line with the first, towards the spine at one end, and towards the lines alba at the other. While the new clusters are appearing, the visicles of the first lose their trasparency, and, on the fourth day, acquire a milky, or yellowish hue, which is soon followed by a bluish, or livid colour, of the bases of the vesicles, and of the contained fluid. They now become somewhat confluent, and flatten, or subside. About this time, they frequently break, and discharge for three or four days, a serous fluid, which, at length, concretes into thin dark scabs. These fall off about the twelfth or fourteenth day, leaving the surface of the subjacent skin in a red and tender state ; and when the ulceration and discharge have been considerable, numerous^cicatrlces, or pits, are left. All the clusters go through a simi- lar series of changes. Young persons, from the age'of twelve to twenty- five, are most frequently affected ; although aged persons are not altogether ex- empt from the complaint, and suffer severely from the pain of it. Summer and autumn are the seasons, in which it is most common. Sometimes it supervenes to bowel com- plaints, and the chronic pains remaining af- ter acute pulmonary diseases. In the treat- ment, Dr. Bateman thinks gentle laxatives, and diaphoretics, with occasional anodynes, when the severe deep-seated pains occur, all that is necessary. No external application is requisite, unless the vesicles be abraded by the friction of the clothes, which are then liable to adhere to the parts : in this case, a little simple ointment inny fbe interposed. For a fuller account,* see Bateman's Pract. Synopsis, p. 226, &c. HER HOR rrj Herpes circinatus , or ringworm, makes its appearance in small circular patches, in which the vesicles arise only round the cir- cumference : these are small, with moderate- ly red bases, and contain a transparent fluid, which is discharged in three or four days, when little prominent dark scabs form over them. The central area, in each vesicular ring, is at first free from any eruption ; but the surface becomes somewfeat rough, and of a dull red colour, and throws off an exfo- liation, as the vesicular eruption declines, which terminates in about a week, with a falling off of the scabs. A succession of these vesicular circles usually arise on the face and neck, or arms and shoulders, thus protracting the case for two or three weeks. The itching and tingling, which are the only inconveniences of the affection, may be relieved by the application of the popular remedy ink, solutions of the salts of iron, copper, zinc, borax, alum, &.c. Some addi- tional interesting observations on other forms of the herpes circinatus, may be found in Dr. Bateman’s Synopsis, from which I have ex- tracted the few preceding particulars. Herpes Prcepulialis. This local variety of herpes was not noticed by Dr. Willan, and we are indebted to Dr. Bateman for a de- scription of it. The complaint begins with extreme itching, and with some sense of heat in the prepuce, on which one or two red patches occur, about the size of a silver penny. Upon these are clustered five or six minute transparent vesicles. In twenty-four or thirty hours, the vesicles enlarge, become of a milky hue, and lose their transparency ; and on the third day, they are coherent, and have almost a pustular appearance. If the eruption is seated on that surface of the pre- puce, which is next the glans, so that the vesicles are kept moist, they commonly break about the fourth or fifth day, and form a small ulceration upon each patch. This discharges a little turbid serum, and has a white base, with a slight elevation at the edges ; and by an inaccurate, or inexperien- ced observer, it may be readily mistaken for chancre, more especially, if any escharotic has been applied, which produces irritation, and a deep-seated hardness, like that of a true chancre. If not irritated, the slight ul- ceration begins to heal about the ninth or tenth day. When the patches occur on the outside of the prepuce, the duration of the eruption is shorter, and ulceration does not actually take place. In the treatment, Dr. Bateman recommends the avoidance of all stimulating, and moist, or unctuous applications ; and if the complaint be within the prepuce, he advises the inter- position of a little bit of dry lint between the sore and the glans. As this gentleman has truly remarked, this case is particularly deserving of notice, be- cause it has often been considered and treat- ed as a chancre. For a great deal more valuable informa- tion respecting Herpes, I beg leave to refer the reader to the publications of Drs. Willan and Bateman, and also to the article Herpes , written by this last able physician for Dr. Rees’s Cyclopa?dia. HORDEOLUM, (dim of hordcum , bar- ley.) A little tumour on the eyelid, resem- bling a barley corn. A Stye. As Scarpa remarks, the stye is strictly only a little boil which projects from the edge of the eyelids, particularly often near the great angle of the eye. This little tumour, like the furunculus, is of a dark-red colour, much inflamed, and a great deal more painful than might be ex- pected, considering its small size. The latter circumstance is partly owing to the vehe- mence of the inflammation producing the stye, and partly to the exquisite sensibility and tension of the skin which covers the edge of the eyelids. On this account, the hordeolum very often excites fever and rest- lessness in delicate, irritable constitutions; it suppurates slowly and imperfectly ; and, when suppurated, has no tendency to burst. The stye, like other furunculous inflamma- tions, forms an exception to the general rule, that the best mode, in which inflammatory swellings can end, is resolution. For, when- ever a furunculous inflammation extends so deeply as to destroy any of the cellular sub- stance, (he little tumour can never be resol- ved, or only imperfectly so. This event, indeed, would rather be hurtful, since there would still remain behind a greater or smaller portion of dead cellular membrane; which, sooner or later, might bring on a renewal of the stye in the same place .as before, or else become converted into a hard indolent body, deforming the edge of the eyelid. The resolution of the incipient hordeolum maybe effected in that stage of it, in which the inflammation only interests the skin, and not the cellular substance underneath, as is the case on the first appearance of the dis- ease. Now repellent, cold applications are useful, particularly ice. But when the hor- deolum has affected and destroyed any of the cellular membrane underneath, every topical repellent application is absolutely useless, and even hurtful ; and the patient should have recourse to emollient anodyne remedies. The hordeolum and eyelids should be covered with a warm soft bread and milk poultice, which ought to be renewed very often. When a white point makes its ap- pearance on the apex of the little tumour, Scarpa says, the surgeon should not be in a hurry to let out the small quantity of serous matter which exists between the skin and dead portion of cellular membrane. It is better that he should wait till the skin within this white point has become still somewhat thinner, so as to burst of ilself, and give a ready vent, not merely to (he little serous matter, but to all the dead cellu- lar membrane which constitutes the chief part of the disease. When the contents of the little tumour are stow in making their way outward, through the opening, the surgeon, gently compressing the base of the stye, ought to force them out. After this, all the symptoms of the disease will disappear, and the cavity, left hv the dead cellular mem- brane, in the centre of the little tumour, will CO HOSPITAL GANGRENE. be found quite filled up and healed in the course of twenty-four hours. Sometimes, though seldom, this process of nature, destined to detach the dead from the living cellular membrane, only takes place incompletely, and a small fragment of yellow dead cellular substance still continues fixed in the cavity, arid hinders the cure. In this circumstance, the further employment of emollient poultices is of little or no service. The surgeon should dip the point of a camel- hair pencil in sulphuric acid, and touch the inside of the stye with it, one or more times, until the sloughy cellular membrane comes away. After this, the small cavity remain- ing will soon close. Should the eyelid con- tinue aflervvard a little swollen and cedema- lous, this affection may be removed by apply- ing the lotioplumbi. acet., containing a little spirit of wine. Some persons are very often annoyed with this disease. Scarpa imputes this most frequently to a disordered state of the primes vice , often met with in persons who live on acrid irritating food, and drink too much spirits.* ( Scarpa , suite Malattie degli Occhi, cap. 2.) HOSPITAL GANGRENE. (Phagedecna Gangreenosa; Putrid, or Malignant Ulcer; Hospital Sore ; Gangroena Contagiosa.) A severe and peculiar species of humid gan- grene, or rather a combination of this affec- tion, with phagedenic ulceration. It is par- ticularly characterized by its contagious or infectious nature ; its disposition to attack wounds or ulcers, in crowded hospitals, or other situations, where many of these cases are brought together ; and its tendency to convert the soft parts affected into a pu- trid glutinous, or pulpy substance, in which no trace of their original texture is discerni- ble. (Delpech, Precis EUm. des Mai. Chir. T. 1 ,p. 123.) It is generally believed to be communicated from one sore or wound to another, by its contagious nature ; but whe- ther the infection can be transferred onlybv actual contact, or both in this way and through the medium of the atmosphere, is a question on which the best authors differ. The first origin ot the disease, however, is a mysterious subject, which cannot invariably be explained on any certain principles, as will be hereafter noticed. From the researches of Mr. Blaekadder, it appears probable, that several of the ancient writers, in their descriptions of foul, gangre- nous bleeding ulcers, must have alluded to the same kind of disease, which is now usu- ally denominated hospital gangrene. Besides the use of the actual cautery, which, accord- ing to the modern French writers, is the surest means of arresting this distemper, seve- ral of the ancients appear also to have em- * I have very often found an alum curd, applied over night in the form of poulliee, of great, benefit in this disease. When made use of just after suppuration has commenced, the tumour discharges in a tew hours, and the patient is freed from a very troublesome and painful companion, it is prepared by putting a piece oi alum, about the size of a pea, into a table spoonftd ot new milk. This^by the feme of a candle, is soon coagulated, and rendered of a consistence fit to be matte use of as a cataplasm. — [Am. Ed.) ployed for the cure arsenical applications ; as, for instance, iEtius, Paulus, Rolandus, Avicenna, Guido, &.c. The only doubt whe- ther these authors actually referred to hospi- tal gangrene, depends upon their not having generally described its contagious nature. But, on this point, I would particularly wish the reader to consult Mr. Blackadder’s valu- able treatise. (P. 76, <^c.) Although La jMotte made cursory mention of hospital gangrene in 1722, under the name of pourrilure, and stated, that it had occurred in the H6tel-Dieu at Paris, yet the first dis- tinct modern account of this disease is con- tained in the 3d vol. of the posthumous works of Pouteau, published in 1783. In the year 1788, Dusassoy, who succeeded Pouteau as chief surgeon of the Hotel-Dieu at Lyons, also published a short treatise on the disorder. The first very accurate des- cription of hospital gangrene, in the Eng- lish language, appeared in the 6th vol. of the London Medical Journal, printed in 1785. The account is entitled “ Observa- tions on the Putrid Ulcer, by Mr. Gillespie, surgeon of the Royal Navy.” In the edition of Dr. Rollo’s work on Diabetes, published 1797, there is a section on this subject, enti- tled, “ A short account of a morbid poison, acting on sores, and of the method of de- stroying it.” In 1799, Sir Gilbert Blane, in the 3d edit, of his book on the diseases of Seamen, gave an account of hospital gan- grene, under the name of malignant ulcer; and Dr. Trotter, in the 2d vol. of his Medi- cina Nautica, published in the same year, described that affection by the same appella- tion. In the 3d vol. of the same work, Dr. Trotter has added to his first account seve- ral valuable communications, relating to this disease, received from surgeons of the Royal Navy. Mr. John Bell has also made hospital gangrene the subject of particular remark, in the 1st vol. of his Principles of Surgery, published in 1801. According to Dr. Thomson, two excellent theses have likewise been published on the subject in the University of Edinburgh ; the first enti- tled “ De Gangrtena Contagiosa,” by Dr. Leslie in 1804; the second by Dr. Charles Johnson, in 1805, under the title of “ De Gangraena Contagiosa Nosocomiale.” (See Lectures on Inflammation, p. 456 — 458.) Professor Thomson’s account of the sub- ject, published in 1813, contained the fullest history of the disease at that time collected. Boyer afterward gave a very fair account of the distemper. (See Trait6 des Mai. Chir. T. \,p. 320, 8t?o. Paris, 1814.) These descriptions were followed by the valuable essay of Delpech, entitled “M6- moire sur la Complication des Plaies?et des Ulccres eonnue sous le nom de Pourriture d’Hdpital;” 1815; some interesting obser- vations by Dr. Hennen, in the London Me- dical Repository for March, 1815; a paper by Professor Brugman, of Leyden, “in the Annales de LitteratUre Med.” vol. 19, 1815; and lastly, the treatise of Mr. Blaekadder, which contains some of the best remarks ever made concerning this affection, and i« HOSPITAL GANGRENE. <5T entitled “ Observations on Phagedsena Gan- graenosa, Svo. Edinb. 1818.” According to Mr. Blackadder, who is a believer in the doctrine of the complaint be- ing only communicable by the direct appli- cation of the infectious matter, when the morbific matter, which produces the disease, has been applied to some part of the surface of the body, from which the cuticle has been removed, as by a blister, one or more small vesicles first appear, which are filled with a watery fluid, or bloody serum of a livid or reddish brown colour. The situa- tion of the vesicle is generally at the edge of the sore. Its size is not unfrequeutly that of a split garden pea, and is easily rup- tured, the pellicle which covers it being very thin. When the vesicle is filled with a watery fluid, and has not been ruptured, it assumes the appearance of a grayish-white or ash-coloured slough ; but, when it con- tains a dark-coloured fluid, or has been rup- tured, it puts on the appearance of a thin coagulum of blood, of a dirty, brownish, black colour. During the formation of the vesicle, there is generally a change in the sensation of the sore, accompanied w r ith a painful feel, like that of the sting of a gnat. After a slough is formed, it spreads with more or less rapidity, until it occupies the whole surface of the original sore; and, when left to itself, (which seldom happens) there is little or no discharge, but the slough acquires daily greater thickness. “ When the formation of the slough has been interrupted, the stinging sensation be- comes more frequent and acute ; phagede- nic ulceration quickly commences ; and such is frequently the rapidity of its pro- gress, that even in the course of a few, hours, a very considerable excavation will be formed, while the parts in the vicinity re- tain their usual healthy appearance.” The cavity, the edges of which are well defined, is filled with a thick glutiuous matter, which adheres strongly to the subjacent parts. When this matter is removed, the surface underneath presents itself of a fine granular texture, which, in almost all instances, is possessed of extreme sensibility, and is very apt to bleed when the operation of cleaning is not performed with great delicacy. At each dressing, the circumference of the cavity is found enlarged, and if there are more than one, they generally run into each other. The progress of the disease is much quicker in some inividuals than others, but it never ceases , until the whole surface of the original sore is occupied. The stinging pain gradually becomes of a darting or lancinating kind ; and either about the fourth or sixth day from the time when the morbific matter had access to the sore, or afterward, at the period of what may be termed secondary inflammation , the lymphatic vessels and glands are apt to become affected. The discharge becomes more co- pious, its colour varying from a dirty yel- lowish white to a mixture of yellow, black, and brown, depending upon the quantity of blood mixed with it. f( The soft parts, in the immediate vicinity of the sore, daily become more painful, tumefied, and indurated ; and, in a great number of cases, particularly in those of plethoric and irritable habits, an attack of acute inflammation speedily supervenes, and is acccompanied by a great increase of pain, the sensation being described to be such as if the sore were burning. The period at which this inflammation begins to subside, is by no means regular. Sometimes it sub- sides in the course of two days, and some- times it continues upwards of five; depend- ing very much on the constitution and pre- vious habits of the patient, as well as the treatment that has been adopted. During its progress, the thick, putrid looking, and frequently spongy slough which is formed on the sore, becomes more and more moist, and of a pulpy consistence. (Hence this form of disease is actually named by Ger- son pulpy gangrene.) In the course of a few days, a very otfensive matter begins to be discharged at its edges. The slough then begins to separate; by and by it is thrown off', but only to prepare the way for an ex- tension of the disease by a continued pro- cess of ulceration, and by a recurrence of the last-mentioned symptoms. (Blackad- der, on Phagedcena Gangrcenosa, p. 28 — 30.) The first symptoms, which indicate hospi- tal gangrene in a wound, or ulcer, are, a more or less acute pain, and a viscid whi- tish exudation on the surface of the granu- lations, which lose their vermilion colour, and present at several points spots of a gray- ish or dirty-white hue, resembling venereal ulcers, or aphthae. These ulcerated points, thus engrafted (as it were) upon the original ulcer, soon spread, and join together, so as to give to the whole surface of the solution of continuity a gray ash-colour. The surface also becomes more or less indurated, and sometimes bleeds. A red, purplish oedema tous circle, of a greater, or lesser extent, is next formed in the surrounding skin. Some times, when the patient is of a good habit, the causes of infection less active, and the constitution sufficiently strong, the disorder now stops. According to Boyer, it may not even extend to the whole surface of the ul- cer. But, most frequently, its progress is ex- tremely rapid, and occasionally quite terri- fying. The edges of the wound, or ulcer, become hardened and everted, the granula- tions are large and tumid, being swelled up, as Boyer asserts, with a considerable quan- tity of gas. They are afterward detached in the form of soft reddish sloughs, which very much resemble the substance of the foetal brain', in a putrid state. From day to day, until either nature alone, or aided by art, puts limits to the disorder, it invades new parts both in breadth and depth, so that its ravages extend to aponeuroses, muscles, blood-vessels ; nerves, tendons, the perios- teum, and even the bones themselves. Among a number of severe cases, which fell under the notice of Mr. Blackadder, there was one, in which the half of the cra- nium was denuded, the bones having be- come black as charcoal, and the integument? HOSPITAL GANGRENE. r>2 detached posteriorly to the second cervical vertebra, and anteriorly to the middle of the zygomatic process of the temporal bone ; and this was originally a superficial wound of the scalp. In another case, the muscles, large arteries, and nerves of both thighs were exposed and dissected, the integu- ments and cellular substance being entirely removed, with the exception of only a nar- row strip of the former, which remained on the outer side of the thighs. This was also originally a simple flesh wciuiid. In other instances, the cavities of the knee, ankle, elbow, and wrist, joints, were laid extensive- ly open, and, in one unfortunate case, the in- teguments and cellular substance, on the anterior parts of the ueck, were destroyed, exhibiting a horrid spectacle, the trachea being also wounded.” (On Phagedcena Gan- grcenenosa, p. 3.) According to the last experienced author, when the disease attacks an old sore, where a considerable depth of new flesh has been formed, the first thing generally observed is a small dark-coloured spot, usually situated at the edge of the sore. But, he states, that in several cases of ulcers, the disease, when carefully watched, was found to begin in the form of a vesicle, filled with a livid, or brownish-black fluid, which afterward burst and assumed the appearance of the dark-co- loured spot, which is commonly first noticed. Mr. Blackadder always found, that, when there had been a considerable bed of new flesh formed, the phagedenic ulceration made comparatively a very slow progress, and put on rather the appearance of mercu- rial phagedaena, until the morbific matter had found access to the natural texture of the part, when the progress of the disease became suddenly accelerated ; acute inflam- mation supervened ; and a large slough xvas formed. (Op. cit. p. 31.) He notices, that when the morbific matter is inserted in a puncture, or scratch, the first progress of the disease bears a resemblance to that of a part inoculated with vaccine matter. The primary inflammation in gangrenous phage- tiaena commences at the end of the second, or early on the third day ; the inflammation is at its height about the sixth ; when the scab begins to form in one disease, phagede- nic ulceration begins in the other, and when allowed to proceed, soon affords sufficient proof of the non-identity of the two diseases. (P. 33.) According to Mr. Blackadder, when the disease attacks a recent gun-shot wound, the discharge, two or three days after infection, is found to be lessened, and to have become more of a sanious, than purulent nature. The sore has a certain dry and rigid appear- ance ; its edges are more defined, somewhat elevated, and sharpened ; the patient is sen- sible of a change in the usual sensation in the sore, and complains of the occasional stinging sensation, resembling that produced by the sting of a gnat. At this period, but sometimes a day or two later, the integu- ments at the edge of the sore become in- flamed, and the surface of the sore itself as- sumes a livid or purple colour, and appears as if covered with a fine pellicle, such as is formed on a coagulum of blood.” (On Phagedcena Gangrcenosa , p. 33.) At Bilboa, the disease in cases of wound, is said generally to have commenced with a sudden attack of severe pain in the head and eyes, tightness about the forehead, want of sleep, loss of appetite, a quick pulse, and other febrile symptoms ; while the wound, which had been healthy and granulating, at' once became tumid, dry, and painful, losing its florid colour, and assuming a dry and glossy coat. (tlennen on Military Surgery , p. 214, Ed. 2.) When left to itself, the above-described pellicle gradually increases in thickness, forming what has been termed a slough. But, Mr. Blackadder observes, that at this period, the progress of the disease is hardly in any two instances precisely alike. Generally, in the course of from five to ten, or fifteen days, a thick spongy, and putrid- looking slough is formed over the whole surface of the sore, and which is more or less of an ash, or blackish-brown colour. When the pellicle is destroyed, as frequently hap- pens in the process of cleaning, it is not in every case reproduced ; but, an offensive matter begins to be discharged, which be- comes daily more copious, is of a dirty yel- low' colour, and ropy consistence, and is very adherent to the sore. The substance, w'hich formed the apparent bottom of the wound, is raised up, and pushing the edges, makes the sore appear considerably enlarged, The edges, which are usually jagged, or pectinated, become extremely irritable, of a deep red colour, and dotted on their inner surface, with numerous small elevated, and angry-looking points, which may be consider- ed as one of the characteristics marks of the disease. The surrounding integuments be- come indurated and inflamed, assuming, not unfrequently, an ansarine appearance ; and the patient complains of a constant burning, lancinating pain. In the vicinity of the sore, the integuments become more and more of a dark red colour, in consequence of the violence of the inflammation, w hich is of an erysipelatous nature, and apt to ter- minate in sloughing, and carry off' the pa- tient. However, the inflammatory symptoms are sometimes mild, and in other cases, ex- ceedingly violent ; a fact accounted for by differences oLconstitution. ( Blackadder , p. 34.) In the hospitals at Bilboa, if the incipient stage was overlooked, the febrile symptoms very soon became aggravated ; the skin around the sore assumed a highly florid co- lour, which shortly became darker, then bluish, and at last black, with a disposition to vesicate; while the rest of the limb be- trayed a tendency to cedema. All these threatening appearances occurred within twenty-four hours, and at this period also, the wound, whatever might have been its original shape, soon assumed the circular form. The sore now acquired hard, prominent, ragged edges, giving it a cup-like appear- ance, with particular points of the lip of a HOSPITAL GANGRENE. G3 dirty yellow hue, while the bottom of the cavity was lined with a flabby blackish slough. The’gangrene still advancing, fresh sloughs were rapidly formed ; the increasing cup-like cavity was filled up and over-topped by them, and the erysipelatous livor and ve- sication of the surrounding skin gained ground, while chains of inflamed lymphatics could be traced from the sores tothe adjoining glands, these exciting inflammation and sup- puration, which often furnished a new nidus for gangrene. The face of the sufferer as- sumed a ghastly anxious appearance; his eyes became haggard, and deeply tinged with bile; his tongue covered with a brownish, or blackish fur; his appetite entirely failed; and his pulse was feeble and accelerated. In this stage, the weakness and irritability of the patient was such, that the slightest change of posture put him to torture, in- creased by his inability to steady the iimb, which, if lifted from the bed, was seized with tremors and spasmodic twitches. (Hen- nen's Military Surgery, p. 215, 216, Ed. 2.) Authors vary considerably in their descrip- tions of the state of the tongue. Dr. Hen- nen found it brownish, or blackish ; Delpech whitish, or yellowish, (Pr6cis. Elem. T. 1. p. 125,) and Mr. Blackadder, covered with a white mucus. (P. 39.) It is explained by Mr. Blackadder, that when the disease attacks a large recent wound, the whole surface of the injury is sometimes affected from the first ; while, in other instances, the disorder commences on, or near the lips of the sore. When the pa- tient is of aa inflammatory diathesis, the sore is generally attacked with acute inflammation between the seventh and fourteenth days; the slough becomes softer, and of a pulpy consistence ; matter, of a strong, and pecu- liar odour, and of a dirty brownish gray co- lour, begins to ooze out at its edges, and be- comes daily more copious. The inflamma- tion gradually subsides ; the slough becomes loosened, and finally detached, leaving the subjacent muscles, bones, fascia;, or liga- ments, completely exposed. When the con- stitution is not prone to acute inflammation, the slough remains long adherent ; the dis- charge is very copious, and burrows under the skin, which then mortifies. Sometimes, after the detachment of a slough, florid gra- nulations spring up, and, notwithstanding a slight recurrence of the phagedenic ulcera- tion, the parts heal up by the almost unasisted operations of nature. However, most com- monly after the muscles are exposed, they continue to be gradually dissected ; their connecting cellular membrane is completely destroyed, and they are left covered with an offensive, greasydooking matter. According to Mr. Blackadder, when a muscle has-been wounded, it swells some- times to a great size, and quickly assumes the appearance of a large coagulum, being altogether deprived of irritability. When it has not been wounded, but has become inflamed, it generally assumes a pale colour, with an appearance as if distended with a fluid, and, occasionally, before losing its vitality, acquires a very surprising bulk ; but when no inflammation has supervened, the muscles become of a pale brick colour, waste away daily, and the patient loses all power in them. As the disease advances, the integuments are undermined and slough ; and hemorrhage from small vessels is a com- mon occurrence ; but, in a more advanced stage, some of the large vessels are apt to give way, and the bleeding from them fre- quently destroys the patient. “ When a stump is the site of the disease, and the patient is of a plethoric habit, or ac- customed to live freely, the symptoms soon begin to indicate the existence of an intense inflammatory action through its whole sub- stance, the tumefaction, pain, and heat in- ci'ease rapidly, so that, in a few days, the stump shall have acquired more than twice its former size, being at the same time much indurated, and causing the most excruciating pain. In this state, the patient has, in some instances, become delirious, and has been cut off by an effusion taking place into some of the larger cavities. It more commonly happens, however, that gangrene seizes upon the integuments, and cellular substance ; large sloughs are thrown off ; and some of the large blood-vessels giving way, the pa- tient sinks under the effects of repeated he- morrhage. For it is commonly found, that the usual modes of stopping hemorrhage from a stump are, in such cases, either inad- missible, or totally inefficacious. 11 Sometimes, the progress of the disease in a stump is more gradual, but in the end nearly as fatal ; the inflammation is much less acute ; there is comparatively but little tumefaction, and the pain is much less se- vere ; but, the discharge is much more co- pious, and the cellular substance, connecting the integuments and muscles, is rapidly des- troyed. Hemorrhage generally comes on later than in the preceding instance, but it is the most common cause of death,” (Black- adder on Phagedcena Gangrcenosa, p. 33 — 39.) It is observed by another writer, that ar- tery seems to be the texture, which resists most powerfully the destructive action of hospital gangrene ; (Thomson's Lectures, p. 460) a remark quite at variance with the statement of Delpech; (Precis EUm.T. 1, 129) but intended to refer, as I conceive, to cases in which the femoral, brachial, or other large artery is seen for several days completely denuded, in the midst of the ra- vages of the distemper, yet not giving way. I have seen the same thing frequently exem- plified in mercurial phagedama, as well in the groin, as in the arm. As for the smaller arteries, they are quickly destroyed, to- gether with other parts. “ In some rare cases (says Dr. Hennen) I have seen the femoral and axillary artery pulsating awfully, and apparently unaffected with disease ; while all the surrounding parts were completely destroyed ; but in a vast majority of cases, the blood-vessels partook of the general disease, in which they were imbedded. They were not only completely HOSPITAL GANGRENE. <34 separated from their natural connexions, but their coats sloughed away at the imme- diate point of disease, while the, disposition extended far beyond the apparently affected spot. Hence, our ligatures but too often failed on the main branches, and any attempt on the smaller was invariably injurious. VVe were here naturally induced to lie the artery considerably above the seat of the disease ; and this was done once on the femoral, and twice on the axillary artery below the clavicle ; the former burst on the third, each of the latter, on the second day afterward.” Dr. Hen nen further remarks, that, in general, the great vessels sloughed long after the acute symptoms of the disease had abated, and that, in severe cases, the eleventh day of the disease was always dreaded. {On Military Surgery , p. 221, Ed. 2.) The in- disposition of the large vessels to close, when taken up in the common way, appears re- ferable to three causes, viz. the tendency to rapid ulceration in the arteries in the situa- tion of the ligatures ; the formation of no effectual coagulum in the extremity of the vessel, like what happens in other cases of mortification ; and the general incapacity of nature in examples of hospital gangrene to establish any process, which can be accompanied with healthy adhesive inflam- mation. In the last stage of the disease, as it oc- curred in the military hospitals at Bilboa, the surface of the sore was constantly cover- ed with a bloody oozing, and, on lifting up the edge of the flabby slough, the probe was tinged with dark-coloured grumous blood, with which also its track became immediate- ly filled. Repeated and copious venous bleedings now came on, which rapidly sunk the patient; the sloughs, whether they fell off spontaneously, or were detached by art, were quickly succeeded by others, and brought into view thickly studded specks of arterial blood. At length, an artery gave way, which was generally torn through in the attempt to secure it with a ligature ; the tourniquet, or other pressure was now applied, but in vain ; for, while it checked the bleeding, it accelerated the death of the limb, which became frightfully swelled and horribly fetid. Incessant retchings came on, and with coma, involuntary stools, and hiccough, closed the scene. Often, however, the patient survived this acute state of the disease, and sunk under severe irritation, absorption of putrid matter, and extensive loss of substance, with common hectic symptoms. (See Hennen's Mil. Surgery, p. 217, Ed. 2.) In the disease at Bilboa, the skin and cellular substance seemed to be the parts originally and principally affected. This, says Dr. Hennen, was obvious, even in the living body ; but, on dissection, the disease of these parts was frequently ob- served to spread much further, than external appearances indicated, as a diseased track was often found running up into the groin, or axilla, and completely dissecting the muscles and great vessels. (On Military Surgery , p. 219, Ed . 2.) When the disease had occupied the outside of the chest, the same gentleman found the lungs in two cases, and the pericardium in a third, cover- ed with gangrenous spots ; and, when the parietes of the abdomen had been attacked, lie often observed the same appearances on the liver. (P. 220.) Hospital gangrene must be regarded, as one of the most serious and dangerous com- plications, to which wounds and ulcers are liable. When the solution of continuity is large, or of long standing, the disorder com- mits great ravages, renews its attacks repeat- edly, and the relapses prove exceedingly obstinate. The same thing is said to happen, when it affects persons labouring under scorbutic or venereal complaints. Hospital gangrene proves particularly dangerous, and mostly fatal, when it complicates large con- tused wounds, attended with badly fractured bones. All the soft parts of the injured limb are then frequently observed to be progressively destroyed, and the unfortunate patient falls a victim, either to typhoid symptoms, frequent hemorrhages, or hectic complaints. From what has been stated, however, the disease varies considerably in its severity in different cases, being some- times of small extent, and even capable al- most of a spontaneous cure. Patients have been known to continue afflicted more than a month, and when the duration of the dis- ease was thus lengthened, the cases almost always had a fatal termination. In a few cases, the wound puts on a favourable appearance again between the sixth and ninth days ; and, in slight examples, the amendment is manifested between the third and fifth. Whatever may be the period of the complaint, its wished-for termination is always announced by a diminution of pain ; the pus acquiring a white colour, and more consistence, and losing its fetid nauseous smell. The edges of the ulcer subside, while its surface Tvecoraes less irregular, and puts on more of the vermilion colour. The red, purplish, cedematous circle, which sur- rounds the disease, assumes a true inflam- matory nature, and the solution of conti- nuity, restored to a simple state, heals up with tolerable quickness, even when the destruction of soft parts is somewhat con- siderable, unless any fresh untoward circum- stances occur to interrupt cicatrization. But, sometimes, when (he patient is on the point of being completely well again, his condition is suddenly altered for the worse ; ulcerated spots make their appearance on the cicatrix, and these spreading in different directions occasion a relapse, which may happen several times. From numerous cases of this disease, seen by Mr. Blackadder at Passage in Spain, this gentleman made the following conclusions : 1. That the morbid action could almost always be detected in the wound, or sore, previous to the occurrence of any constitutional affection. 2. That in Several instances, the constitu- tion did not become affected, until some HOSPITAL GANGRENE. 05 considerable time after the disease had mani- fested itself in the soie. 3. That when the disease was situated on the inferior extremities, the lymphatic Vessels, and glands in the groin, were ob- served to be in a state of irritation, giving pain on pressure, and were sometimes en- larged, before the constitution showed evi- dent marks of derangement. 4. That the constitutional affection, though sometimes irregular, was in many cases contemporary with the second, or inflamma- tory stage. 5. That all parts of the body were equally liable to become affected with this disease. 6. That, when a patient had more than one wound, or sore, it frequently happened, that the disease was confined to one of the sores, while the other remained perfectly healthy, and that even when they were at no great distance from each other. (On Phagedena Gangrcenosa, p. 19.) Thus Mr. Biackadder espouses the opinion, that hospital gangrene is at first a local, and not a constitutional disease, that is to say, not necessarily preceded, or originally accom- panied by any diseased action in the system. It is highly important to weigh this distinc- tion well, not only because it is yet the chief point of difference among the best writers on the subject, but because it involves very directly every theory respecting the causes of the disease, and the great question, whether its ravages are to be resisted princi- pally by local or constitutional means, or by remedies of both descriptions together. In the hospital gangrene, observed by Dr. Rollo in the artillery hospital at Woolwich, “ The action of the poison seemed to be limited and confined to specific effects. The Jirst were local, producing only a general affec- tion, by a more extensive operation on the sore. Five or six days from the appearance of (he small ulcer or ulceration, when it had ex- tended over one-third of the former sore, with pain and redness in the course of the lymphatics, and the glands, through w f hieh they led, with enlargement of them, general indispositon of the body became evident.” Delpech, in his interesting memoir, particu- larly notices, that the constitutional symp- toms always occurred the last in order of succession. Mr. Biackadder distinctly declares, that, in no instance, which he had an opportunity of observing, did the constitutional symp- toms of gangrenous phagedama precede the local, unless the case be held an exception, in which a stump became affected, alter amputation had been performed, on account of Hie previous effects of the disease. The period at which the constitution begins to exhibit symptoms of irritation (he says) is extremely irregular, — sometimes as early as the third, or fourth day, and sometimes even as late as the twentieth. The countenance assumes an anxious or feverish aspect ; the appetite is impaired ; the desire for liquids increases ; and the tongue is covered with a white mucus. The bowels are generally rather constipated : and the pulse, what Vol. If 9 may be termed, rather irritated, than accele- rated. Bur, the general symptoms may assume an inflammatory, or typhoid charac- fer, according as the causes of one of these modifications may predominate. According to Mr. Biackadder, when an inflammatory diathesis prevails, the system becomes gradu- ally more irritated, until an attack of°acutc inflammation seizes upon the sore, and which frequently happens about the end of the second week. At this pe iod, the pulse is frequent arid sharp, and it is not uncommon for the patient to be seized with one, or more shivering fits, succeeded by a great increase ot heat, but seldom, or never termi- nating in a profuse perspiration. The cold fit is sometimes followed by a bilious dis- charge from the intestines, and mitigation of the febrile disorder. If the local mischief be not arrested, the strength becomes daily- more and more exhausted ; the fever losers its inflammatory character ; and, unless the patient be cut off by hemorrhage, he falls a victim to extreme debility. When the dis- ease has a typhoid character, the pulse is small and frequent ; the appetite and strength gradually fail ; and the patient at last sinks, retaining his mental faculties to the last. Not unfrequentlv diarrhoea has- tens the event. (Biackadder on Phagedccno, Gangrwnosa, p. 39, 40.) On the other band, the generality of wri- ters, nay, even some of those who represent the disease as always proceeding from a species of infection applied to the wound, take into the account the operation of con- stitutional causes, as predisposing to, and of course preceding the local symptoms. Dr J. Thomson believes, that the constitutional symptoms mostly precede the local. (On Inflammation ,p. 459.) The same sentiment is professed throughout Dr. Herinen's re- marks, who placed reliance chiefly upon internal remedies, and regarded external applications, as merely a secondary object. ( On Military Surgery, p. 222, Ed. 2.) To this part of the subject, I shall return, after adverting to the causes of hospital gangrene. The hospital gangrene, which occurred in the Artillery Hospital at Woolwich, and was described by Dr. Rolio, did not attack .speci- fic sores : venereal, scrofulous, and vario- lous ulcers were not attacked, although (he patients lay in the wards, where the disease prevailed. Professor Thomson admits, that specific sores are less liable to attacks of hospital gangrene, than common wounds and ulcers • but, he declares, that he has frequently seen it attack cancerous and venereal ulcers (On Inflammation, p. 460.) Dr. Hennen mentions a remarkable in- stance, which also proves the possibility of a specific sore becoming affected, and fatal from this cause in forty-eight hours after rhV patient had first been exposed to the infec- tion. Dr. Hennen relates the tact to prove that the contagion may be received, without a long residence in a tainted air. The patient, “ who had just landed from Eng- land, and was under (he influence of mereu- HOSPITAL GANGRBNU. 66 vy, employed for a venereal complaint, died within forty-eight hours after his admission, the gangrene having seized on an open bubo in his groin, eroding the great vessels in the neighbourhood, and absolutely destroying the abdominal parietes to a large extent.” (P rinciples of Military Surgery , p. 218, Ed 2.) The effects of hospital gangrene should be carefully discriminated from those of the scurvy. Ulcers, attacked with hospital gan- grene, are not affected in any degree, like scorbutic ulcers, by the use of vegetable diet and lemon-juice, and they occur among men, who are fed upon fresh meat and vegetables, as readily as they do among those who have been fed altogether upon salt provisions. ( Thomson’s Lectures on Inflammation, p. 482.) Hospital gangrene is almost always accom- panied with severe febrile symptoms : but, as to fevers, (says Dr. Lind.) it may indeed be doubted whether there be any such as are purely and truly scorbutic. The disease is altogether of a chronic nature ; and fevers may be justly reckoned among its adven- titious symptoms.” ( Treatise on the Scurvy , p. 106.) In cases of hospital gangrene, the geueral symptoms of scurvy are also abselit, such as soreness and bleeding of the gums, livid blotches and wheals on the fleshy part of the legs, cedematous ankles, Lc. Hospital gangrene (says Boyer) is a spe- cies of humid gangrene, which attacks in some degree epidemically the wounds and ulcers of patients, who happen to be crowd- ed together in an unhealthy place. Its occasional causes are ; the situation of an hospital upon a low marshy ground; the vicinity of some source of infection ; the uncleanliness of the individuals, or of the articles for their use ; the crowded state of the wards, especially when they are small and badly ventilated ; lastly, every thing that tends to corrupt the air which the pa- tients breathe An infected atmosphere may produce in the most simple wounds unfavourable changes, partly, as Boyer con- ceives, by its immediate action on the sur- face of the wound, but no doubt princi- pally by its hurtful influence upon the whole animal economy. The foregoing causes have also sometimes produced alarm- ing and obstinate gangrenes of an epidemic kind, or at least, a state of the constitution, under the influence of which all wounds and ulcers constantly took on a bad aspect, and were often complicated with the most gangrenous mischief. Vigaroux saw such an epidemic disease prevail for twenty months in the two hospitals of Montpellier, and he states, that the most powerful anti septics were of little avail against the dis order, which often invaded the slightest scratches. In general, this epidemic species of gan- grene is not observed in new-built hospi- tals, nor in those which are erected out of the central parts of cities, upon high ground. Hospital gangrene may occur in any sea- son ; but, it is most common after the sultry heat of summer. A bilious constitution, mental trouble, un- wholesome or insufficient food, a scorbutic diathesis, great debility, and fevers of a dangerous type, are also reckoned by the French surgeons as so many predisposing causes of hospital gangrene. The observations of Pouteau, and those of some other practitioners, convincingly prove, that hospital gangrene may be com- municated to the most simple wound, or ulcer, in a subject of the best constitution, and breathing the purest air, by merely putting into contact with such wound or ulcer, sponges, lint, or charpie, impregnated with the infection of this peculiar disorder. But, this inoculation is conceived to be the more alarming, and to take effect the more quickly, in proportion as patients have been more exposed to the influence of such cau- ses as are themselves capable of producing the disease, and also in proportion as the kind of constitution predisposes to it. Although the contagious nature of hospi- tal gangrene has been generally admitted by all the best informed writers on the sub- ject, the doctrine was not considered by Dr. Trotter as having a good foundation. Mo- dern authors, however, have not joined this latter gentleman, and Dr. J. Thomson, Dr. Hennen, and Mr. Blackadder, all believe, that the disorder is infectious. “ The con- tagious nature of hospital gangrene (says Professor Thomson) appears to me to be sufficiently proved, 1st, By the fact, that it may be communicated by sponges, charpie, bandages, and clothing, to persons at a dis- tance from those infected with it. 2dly, By its having been observed to attack the slight wounds of surgeons, or their mates, who were employed in dressing infected per- sons ; and that, even in circumstances, where the medical men so employed, did not live in the same apartment with the in- fected. 3d!y, By our being able often to trace its progress distinctly from a single in- dividual through a succession of patients. 4thly, By its attacking recent wounds, as well as old sores, and that in a short time after they are brought near to a patient af- fected with the disease. Stilly, By our be- ing able to prevent the progress of the dis- ease in particular situations, by removing the infected person, before the contagion, which his sores emit, has had time to ope- rate. 6thly, By its continuing long in one particular ward of an hospital, or in one particular ship, without appearing in other wards, or ships, if pains be taken to prevent intercourse between the infected and unin- fected.” (Lectures on Inflammation, p. 4S4.) But, although there can be no doubt of the disease spreading partly by its conta- gious nauire, it appears to me equally cer- tain, that the number of cases is also often increased by the continued operation of the. same causes, which produced the earliest instance of the disorder in any particular hospital. it is alleged, that when once a patient has taken the infection, he cannot avoid the consequences, whatever precautions he may adopt. Thus, Boyer informs us, that HOSPITAL GANGRENE. 67 helms seen hospital gangrene take place in wounded patients, who, in the hope of es- caping this epidemic affection, had quitted the infected hospital, and retired to elevated situations, where they breathed the most salubrious air. (See Traitd de Mai. Chir , T. \, p. 322.) The bad state of the air of a crowded hos- pital, as Mr. Blackadder observes, is a ready means of accounting for the origin of pha- gedena gangrenosa ; but, there are various reasons fur considering such explanation not altogethersatisfactory ; and he mentions a case, in which the wound of a soldier was found affected with the disease on his first arrival at an hospital, after having been ac- cidentally detained, with two other wound- ed comrades, for five or six days, partly in an open building, and partly in a boat, quite exposed to stormy weather. ( P . 45.) Dr. Hennen likewise gives an account of about thirty fresh wounded men, in whom hospi- tal gangrene first appeared in their journey from Viltoria to the hospital near Bilboa. (Principles of Military Surgery, p. 214, Ed. 2.) Dr. Rollo also remarked, that some men in quarters were affected with thisdis- ease. And, according to Air. J. Bell, ‘There is no hospital, however small, airy, or well regulated, where this epidemic ulcer is not to be found at times.” ( Principles of Sur- gery ', Vol. 1, p. 112.) For a refutation of the opinion, that the disease ever strictly merits the epithets endemial, and epidemic , I must refer the reader to the observations of Mr. Blackadder. (P. 143. 53.) Delpech remarks, that the causes of the disease do not appear to have depended upon the state of the atmosphere, (P. 25;) and in almost every instance, he traced the propagation of the disorder to the direct application of the morbific mailer to the sores. However, he joins Pouteau in the belief, that it may be communicated through the medium of the atmosphere ; an occurrence, which Air. Blackadder doubts, or, rather considers as very rare, and only possible where the ef- fluvia are allowed to accumulate in a most negligent manner, so as to resemble a va- pour bath, which mode he would also regard as equivalent to inoculation. (On Phngedce- na Gangrcenosa , p. 156.) On the whole, I am disposed to think the views, which Mr. Blackadder has taken of the manner in which the disease is communicated, the most correct, hitherto published, and that, while particular states of the air and consti- tution certainly modify the disorder, they cannot generally have any share in giving origin to the disease ; I say generally, be- cause as various facts oblige us to admit, that hospital gangrene sometimes arises, without having been communicated from any patient previously affected, it is impos- sible to assert, that the earliest example of it, under such circumstances, may not arise from the operation of some unknown and inexplicable circumstances on the constitu- tion, or in other words, from the state of the system itself. Nor can a doubt be 'en- tertained, that, at all events, the disorder is most apt to break out in crowded, Badly- ventilated hospitals, and in them appear more extensively and malignantly, than in others, which are well-regulated, properly ventilated, and healthily situated. But, the idea, entertained by Delpech, that hospital gangrene may originate from the same con- tagion as typhus, or other diseases, is a mere unsupported, irrational conjecture, quite as destitute of the truth, as the suppositions about the endemial and epidemic character of the complaint, independent of its infec- tious nature. The question, how the first example of the disorder originates, is at pre- sent a perfect mystery ; but, as ii cannot be referred to contagion, or inoculation, we should recollect, that whatever produces it in one individual, may produce it in ano- ther, similarly circumstanced, and, on this principle, the disorder may sometimes be formed independently, and at the same time, in a greater or lesser number of patients in the same hospital, as well as spread from these to others by infection. With the view of preventing the disor- der, the wards. in which the wounded are placed, should riot be crowded ; they ought to be freely ventilated, and, if possible, not communicate. The utmost attention to cleanliness should be paid ; and all tilth and stagnant water removed. It lias been asserted, but with what accuracy 1 cannot determine, that the predisposition of the wounded to this species of gangrene may be lessened bva well-chosen diet, by drinksaci- dulated with vegetable acids, or with the sul- phuric acid, and by the moderate use of wine. The state of the stomach and bowels should be particularly attended to, and, if out of order, emetics and purgatives ought to be immediately employed, and repeated ac- cording to circumstances. The dressings should be applied with extreme attention to cleanliness, and too much care cannot bo taken to prevent the infectious matter of one wound from coming into contact with another through the medium of sponges, in- struments, &c. “ Whatever may be the. source of this disease (says a late writer) it is atleast'sufliciently ascertained, that, when it occurs, its propagation is only to be pre- vented by the most rigid attention to clean- liness, and by insulating the person, or per- sons affected, so as to prevent all direct in- tercourse between them and the other pa- tients ; for, so far as I have had an oppor- tunity of observing, ninety-nine cases in the hundred were evidently produced by a di- rect application of the morbific matter to the wounds, dressings, &,c. ; while others, who were, in every other respect, equally exposed to its operation, never caught the disease. Tti attempting to prove this by ex- periment, I have placed three patients with clean wounds alternately between three other patients, severely affected with the disease. They lay in a part of a ward, which was appropriated for patients, who were labouring under the disease, and of whom there were at the time a considera- ble number. Their beds were on the floor, 68 HOSPITAL GANGRENE. and not more than two feet distant from each other; but, all direct intercourse Was forbidden, and they were made fully aware of the consequences that would follow from inattention to their instructions. The re- sult of this trial was, that not one of the clean wounds assumed the morbid action peculiar to the disease, nor was the curative process in any degree impeded.” (Black- adder on Phage daena Gangrrenosa, p. 46 .) As many experienced writers assert, that the disease may also be communicated from one person to another through the medium 'of effluvia in the air, I am firmly persuaded that, in the present state of our knowledge of the subject, the cautions, respecting ventilation, cleanliness, (the chief practical deduction from the latter doctrine) are high- ly necessary and important. This sentiment may be adopted, without implicit faith be- ing placed in the opinion, that the disorder can actually be transmitted from one per- son to another through contagion in the air, because whether the last idea be true, or not, attention to cleanliness and ventilation must be beneficial to the health, in this, as in every other species of gangrene ; and, on this principle, they must be serviceable in diminishing the severity, if not the frequen- cy and extent, of the disease, as I am myself disposed to believe from the consideration of all the evidence adduced. Where cir- cumstances will permit, an entire removal of the patients from the place, in which the disease has either had its first forma- tion, or spread to any extent, appears like- wise to be a most beneficial measure. But, when this change of the wards, or hospital, is impracticable, the air which the patients breathe, should be purified, by renewing it as much as possible, fixing ventilators, and especially by using the oxygenated muriatic acid fumigations, as recommended by Guyton-Morveu, or else those of the nitric acid. The nitric acid fumigations are made by putting into a gla>s vessel, on the ground, half an ounce of concentrated sulphuric acid, to which an equal quantity of nitre is to be added gradatim. The mixture is to be stirred with a glass tube, when an abundance of while vapour will be produced. The oxygenated muriatic acid fumiga- tions are made, by mixing three ounces two drams of common salt with five drams of the black oxide of manganese in powder. These two ingredients are to be triturated to- gether; they are then to he put into a glass vessel; one ounce two drams of water are to be added, and then if the ward, or cham- ber be uninhabited, one ounce seven drams of sulphuric acid are to be poured upon the mixture all at once ; or gradually, if the pa- tients are there. This quantity will be suffi- cient for a very large ward. When one or more of the patients, afflict- ed with the disorder, before it has become general, are lying in a badly ventilated part of the ward, the surgeon can partly counter- balance the disadvantage of not having a fresh ward, by causing the patients to be put into a more airy part of the ward, and as far as possible from the quarter, in which they contracted the disease. With regard to internal medicines, while irritation and febrile heat accompany hospi- tal gangrene, diluent acid drinks are proper, such as nitrated whey sweetened with syrup of violets, lemonade, &c. Blood- letting is admissible in bur few instances, not merely because the orifice, made by the lancet, is apt to become gangrenous, but because the fever, which accompanies hospital gangrene, is usually of the typhoid, or astheuic cha- racter. ( Thomson , p. 49 ?.) Mr. Blaeka ider, like Dr. Thomson, does not entertain a favourable opinion of vene- section, as a general practice, though he would not object to the abstraction of a small quantity of blood, when, owing to the plethoric habit of the patient, previous treat- ment, and other causes, an inflammatory ac- tion in the system is present. But he con- ceives, that all danger of the disease attack- ing the A’oundj made with the lancet, may be obviated, if care be taken that the arm of the patient, the hands of the surgeon, his lancet, and the subsequent dressings, be per- fectly free from contamination, and that the patient be prevented from undoing ihe band- age, or touching the incision made with ihe lancet, before it is cicatrized. (P. 135.) Mr. Blackadder thinks, however, that blood-let- ting should be avoided, as much as possible, particularly when the previous injury has been extensive. “ A general debility of the system, is one of the symptoms which are most to be dreaded ; for, when once it takes place, there is no other disease in which it is removed with greater difficulty.” (P. 137.) Mow different these sentiments are from those of Dr. Hennen, who, in speaking of the effects of venesection, when the disorder was accompanied with an inflammatory dia- thesis, employs the following expressions: “ The very patients themselves implored the use of the lancet.” For several months we used no other remedy, cither as a cure, or preventive.” — “We never observed arty of the lancet wounds assume a gangrenous appearance, although previously, in almost every other instance, the slightest puncture festered.” On Military Surgery , p. 224, Ed. 2-> In the beginning of the constitutional at- tack, Pouteau and Dussassoy particularv re- commended emetics, and Mr Briggs, Dr. J. Thomson, and Dr. Hennen, are all advo- cates for this practice, though the latter gentleman makes his evidence rather ambi- guous, by a subjoined note, in which he ment ions that want of success, &,c. led to the trial of venesection. (Op.cit. 222.) As for Mr. Blackadder, he deems the employment of emetics at the commencement of hospital gangrene useful only when the stomach is foul. (On Phagedeena Gang ram osa, p. 134.) In the early stage of the case, writers seem all to agree about the utility of purgative and laxative medicines. When there is debility, good generous wine should be allowed, either by itself, or mixed with lemonade according HOSPITAL GANGRENE. 09 to circumstances. Bark, whose antiseptic qualities have been so highly praised, is in general more hurtful, than useful ; and Dr. Hennen assures us, that he has seen great harm done by large and injudicious doses of this drug, before full evacuations had taken pluce, and the sloughs begun to separate. Boyer allows, however, that it may be bene- ficially given, when the feverish heat has abated, and the debility is very great. In all stages of this disease, unattended with diarrhoea, acids are proper. The sul- phuric acid is that which is given With most success ; but the acidulous tars rite of potassa is also an excellent medicine. From two drams to half an ounce may be given every day, and the best plan is to make an acid drink with it, which should be sweetened and strained. In severe cases, attended with a quick and feeble pulse, depression, restlessness, and anxiety, an opiate becomes necessary. “ So long as we wish to excite a degree of moisture on the skin, (says Professor Thom- son) Dover’s powder, or laudanum with anti- monial wine, form in general the best opi- ates.” This gentleman, however, is not an advocate for the employment of opium, in the early stage of hospital gangrene, while the heat and other febrile symptoms are at their ne'ight (See Lectures on Inflammation, p. 494,495.) For these cases, camphor, in large and frequent doses, was highly praised by Pouteau. From what has been said concerning in- ternal remedies, it is evident, that none of them can be regarded as neans, which can be at all depended upon for arresting the ra- vages of hospital gangrene, however advan- tageous they may prove in palliating general symptom*, removing particular complica- tions, enabling the system to support the ef- fects of the local disorder for a greater length of time, or, in a few cases, even placing na- ture in a condition to throw off the diseased parts herself, and communicate to the subja- cent living flesh a healty action. If credit can be given to several of the authors, who have had the most extensive opportunities of attending to the nature of hospital gangrene, the local treatment is far more effectual than internal medicines. “ I was told by several of the French sur geons (says a late visiter to Paris ) that they did not rely at all on internal means for stopping the progress of hospital gangrene, and that their experience had proved them to be insufficent, if no! wholly inefficacious. Dupuytren, in reply to the account I gave him of the practice and opinions of English surgeons on this subject, assured me, that he had no confidence but in local applications, and that internal remedies alone, as far as he had found, did almost nothing. The same remark has been made in a very recent pub lication on hospital gangrene, ( Delpech , Mim. sur la Complication des Plaies, fyc. 1815.) although it seems to be rather at vari- ance with its being a constitutional and con- tagious disease, which the author has admit- ted.” (See Sketches of the Medical Schools of Paris, by J. Cross, p. 83.) Perhaps, there is not a single antiseptic ap- plication, which has not been tried as a dress- ing for wounds, or ulcers, affected with hos- pital gangrene. All watery applications, and common poultices, and fomentations, are ge- nerally condemned as inefficacious, and even hurtful. Dussassoy was convinced by the observa- tion of numerous cases, that t lie best applica- tion is powder of bark. He recommends the wound to be covereu with several layers of this powder, which are then to be moist- enechwilh turpentine. When this composi- tion dries, he asserts, that it forms a fragile sort of coat, at the sides of which, and through which, the discharge escapes. After twenty-four hours, the first coat is to be re- moved, an I a fresh one applied. In general, according to this writer, four or five such dressings are sufficient in sirnplfe cases, where the disorder is confined to the skin and cel- lular substance. Healthy inflammation then occurs, the sloughs come away, and the wound puts on a healing appearance. In bad cases, D-issassoy sometimes added one-fifth of powdered muriate of ammonia to the bark When th's treatment failed, the actual cautery was used On the subject of bark, as a local applica- tion to hospital gangrene, I need only re- mark, that it is now entirely relinquished, either as possessing no efficacy, ( Delpech ) or even aggravating the symptoms. ( Blackad - der.) The milder forms of the disease appear sometimes to have yielded to the application of the vegetable and diluted mineral adds ; lime juice ; lemon juice ; vinegar; and the diluted nitric, and muriatic acids. And the same observation may be made, with res- pect to solutions of the nitrates of silver and mercury. The two latter substances, and the oxygenated muriatic acid, and ga«, were found by Dr. Rollo to be capable of effecting a cure. Delpech, in particular, speaks of the benefit derived from the application of strong vinegar, after all the pulpy viscid matter has been carefully wiped away from the surface of the living flesh. The vinegar is then poured on the ulcer, which is to be covered with charpie wet with the same liquid. When the case is too far advanced for this trea’ment to answer Delpech tries caustics, especially 1 he nitrate of silver ; and if these fail, he lias recourse to the actual cautery, and, when the sloughs are very thick, so as to hinder the cautery from act- ing to a sufficient depth, he prefers thrusting into the sloughs down to the living flesh an- gular pieces of caustic potash at small dis- tances from each other! (Prdcis. Elem. des Mai. Chir. T. 1, p. 151.) Surely, this must be far more torturing, and less certain of success, than removing the sloughs, and ap- plying the cautery. Though the actual cautery is generally ad- mitted to be one of the most powerful means of stopping the progress of hospital gangrene, the surgeons of this country entertain a HOSPITAL GANGRENE. SO strong aversion to the practice; and Icon- loss, that my own dislike, to it is such as Mould always lead tne to prefer any other treatment, from which equal efficacy would result. At the same time, if must be grant- ed, that if the actual caulery will more cer- tainlyarrest sotneforms of hospital gangrene, than any other known applications, the sur- geon’s duty is to put out of the question his own prejudices against it, and consider only his patient’s welfare. I am far from thinking, however, that, while there are such power- ful caustics as th^ undiluted mineral acids, and a dressing so effectual as a solution of arsenic, it can often be absolutely necessary to employ red-hot irons. The merit of having pointed out in mo- dern times the great efficacy of Fowler’s solution of arsenic, or the liquor arseuiealis of the London Pharmacopoeia, as an appli- cation to phagedaena gangrenosa, belongs to ]\Ir. Biackadder. In answer to the objection, that the external use of arsenic is not unat- tended with danger, he assures us, that he has heard but of one instance of hospital gangrene, in which any deleterious effects were supposed to arise from the absorption of the arsenic, and the patient in question was very soon cured of his uneasy, and pos- sibly merely nervous symptoms ” ( P . 50.) “ The first thing to be attended to in every case of disease (says Mr. Biackadder) is cleanliness , which, if always of great im- portance, is, in this instance, indispensable. The surface of the body ought to be made, and kept perfectly clean, by means ot the tepid bath, or otherwise by a plentiful use of soap; and the linen, and bed-clothes, should be frequently changed, particularly when soiled with matter from the sore.” In order to make the sore perfectly clean, and free it from the viscous discharge, without produ- cing considerable bleeding, and pain, Mr. Biackadder recommends two large tin hos- pital teapots to be filled with a weak solu- tion of the subcarbonate of potass. One of these solutions is to be cold ; the o»her tepid ; because sometimes one, and sometimes the other, is found most agreeable to the patient’s feelings, though the warm is the most effec- tual in cleansing the sore. The liquid is to be poured over the sore, and received into a basin, which ought to be immediately empti- ed into another vessel placed at a distance from the patient. During this ablution, the glutinous matter, which adheres to the sore, may be gently detached, by means of small dossils of fine tow, or lint, but these (says Mr. Biackadder) should never be used lor two different patients, rigid ecomotny, on occasions such as this, being a very mistaken principle. In these cases, the use of sponges, (he justly observes) ought to be entirely laid aside, as they can seldom be used more than once with safely. When the sore has been thus cleaned, a fine piece of dry lint is to be spread over its surface, and gently [tress- ed into all its depressions with the points of the fingers. When the lint is removed, a quantity of the discharge will be found ad liering to it : and this operation must be re- peated with fresh pieces of lint, until the surface of the sore is made perfectly clean and dry. According to Mr. Biackadder, the solution of arsenic will generally be found strong enough, when diluted with an equal part of water; but, in slight cases, it answered, when weakened with twice its quantity of Avater ; and, in a few examples, it was em- ployed without being at all diluted. Several pieces of lint of the same shape as the sore, but a little larger, are to be prepared : one of these, soaked in the solution, is now to be applied to the cleaned surface of the sore, and renewed every fifteen or thirty minutes, according to the time in which it becomes dry. When the heat and inflammation are considerable, great relief will be derived from the frequent-application of linen cloths moistened with cold water, which must be kept from weakening the arsenical solution by means of a, small piece of oilskin laid over the pieces of lint. When the disease extends into the track of a gunshot wound, Mr. Biackadder uses a syringe for cleaning the sore, and introducing the solution. “A slip of fine lint, well soaked in the solution, may also be inserted by means of a probe, into the bottom of the wound ; and when the openings are at no great distance from each other, aud not in the immediate vici- nity of the large nerves and blood-vessels, the lint may be drawn through the wound in the form of a seton. (P. 53.) When the pain, caused by the application, is very se- vere, and the constitution is irritable, and debilitated, Mr. Biackadder prescribes an opiate, though he remarks, that this practice will seldom be absolutely necessary. The morbid action in the sore is destroyed by the arsenical solution sooner, or later, in different cases : the best plan is to continue the application, until an insensible, dark- coloured , dry slough occupies the whole surface of the sore ; and until the patient is com- pletely relieved from the burning and lancina- ting pain. After the slough is formed, Mr. Biackadder employs an ointment, composed of equal parts of the oil of turpentine, and the yellow resinous ointment, or of two parts of Venice turpentine to one of the resinous ointment. 11 These being melted and mixed together, are to be poured over the sore, as hot as the patient can possibly bear.” A pledget of dry lint, or tow, and a bandage, are then applied ; and this dressing may be renewed two or three times a day, the sore being each time carefully washed with the solution of potass. As soon as any part of the slough is loosened, Mr. Biackadder removes it with a pair of curved scissors. With the view of expediting the separation of the slough, he sometimes employs a linseed-meal poultice, which had the desired effect, but was found to he too relaxing. When it is used, there- fore, Mr. Biackadder found it expedient, at each dressing, to touch the new granulations with the nitrate of silver. After the detachment of the. slough, Mr. Biackadder dresses the sore with the above- Hydrocele. tiieulioned ointment cold, or with the addi- tion of a small proportion of the subacetale of copper. The pledget of this ointment is covered with a piece of oilskin, lightly rub- bed over with soap; and a firm bandage is applied to the whole limb. (See Obs. on P/iagedeena Gangreenosa , p. 49, fyc. 8vo. Edinb. 1818.) The author declares, that, after the introduction of the above treatment, (with the exception of stumps attacked with hospital gangrene) he never saw an instance in which the remedy failed, when applied in time and in a proper manner; that is, before the disease had made such progress as to preclude all rational hope of success from that or any other mode of treatment. ( P . 23.) In Dr. Rollo’s treatise on Diabetes, publish- ed in 1797, the opinion is plainly stated, that the progress of hospital gangrene might be slopped by very active topical applications, and, in tae same work Mr. Cruickshank says, that “ it an actual caustic were to be em- ployed, we should have recourse to the strong nitrous acid.” According to Mr. Blackadder, the oxygenated muriate of mer- cury and the nitrous acid were u.ucli recom- mended, and employed by surgeons in the 16th and 17th centuries, as escbaroties, in cases of gangrene and foul ulcers. ( P . 113.) Several army surgeons have informed rue, that the undiluted nitrous acid was success- fully used as an application to hospital gan- grene in the military hospitals at Antwerp in the year 1815; but that other strong acids had an equally good effect. Dr. J. Thom- son also notices, that “the application of caustic substances, such as the strong mine- ral acids, the solutions of potass, corrosive sublimate, and arsenic, seemed at Antwerp to arrest the progress of this sore, without exciting inflammation.” ( Report of Obser- xalions made in the Military Hospitals in Bel - gium.) Delpech was informed by some British surgeons, belonging to the Angio-Portugueze army in the Peninsula, that the muriatic acid was in common use in the hospitals of that army as a local application for checking the ravages of hospital gangrene, being em ployed in a diluted state for slight cases, and in a concentrated caustic form for others. In St. Bartholomew’s hospital , the undilu- ted nitric acid has been used with great suc- cess as a local application to phagedenic gan- grenous ulcers, as may be seen by an inte- resting paper recently published by Mr. Wel- bank. (Med. Chir • Trans. Vol. 10.) Pouteau, Dussasso) , Boyer, and Delpech, all bear testimony to the efficacy of the ac- tu But as I have never seen au instance, in which such disease was restricted to the cel- lular texture of the cord, I am led to sup- pose that it is a very uncommon case. The following is said by Mr. Pott to be the stale of the disease, while of moderate size. The scrotal bag is free from all appearance of disease ; except that when the skin is not corrugated, it seems rather fuller, and hangs lather lower on that side than on the other, and if suspended lightly on the palm of the hand, feels heavier: the testicle, with its ©pididymus, is to be felt perfectly distinct below this fulness, neither enlarged, nor in any manner altered from its natural state : the spermatic process is considerably larger than it ought to be, and feels like a vanx, or like au omental hernia, according to the different size of the tumour : it has a kind of pyramidal form, broader at the bottom than «t the top : by gentle and continued pressure it seems gradually to recede or go up, but drops down again immediately upon remo- ving the pressure; and that as freely in a supine, as in an erect, posture : it is attend- ed with a very small degree of pain or un- easiness ; which uneasiness is not felt in the scrotum, where the tumefaction is, but in the loins. “ If the extravasation be confined to what is called the spermatic process, the opening in the tendon of the abdominal muscle is not at all dilated, and the process passing through it may be very distinctly felt ; but if the cellular membrane, which invests the spermatic vessels within the abdomen, be affected, the tendinous aperture is enlarged ; and the increased size of the distended mem- brane passing through it, produces to the touch a sensation not very unlike that of an omental rupture.” While it is small, it is hardly an object of surgery, and maybe kept from being trou- blesome by means of a suspen&orv ; but When it is large, it is very inconvenient both from size and weight, and according to Pott, the only method of cure which it admits, is far from being void of hazard. The plan is to make a free incision into the swelling, it must be confessed, with a modern writer, that these observations on the diffused hy- drocele of the cord by Mr. Pott, are faf from being satisfactory, and the symptoms, by which he made up his mind to lay open the disease, were but of an equivocal de scription, and might have arisen from cases of another nature. (See Did. dcs Sciences Med. T 22, p. 215.) the encysted hydrocele of the sperm a. - TiC CORD Is a complaint by no means infrequent, especially in children, it was very well known to many of the ancients, and has been accurately described by Albucasis, Cel- su>, Pauius iEgineta, &,c. When Mr. Pott says, that the disease is not infrequent, it ought to be understood, that its frequency, though much greater, than that of the dif- fused hydrocele of the cord, considered as Vor . If. 10 a distinct disease independent of general anasarca, is not at all equal to that of the hydrocele of the tunica vaginalis. Riche- rand has calculated, that the average pro- portion of encysted hydroceles of the cord to those of the latter description, is not more than as 1 to 200. ( JYosogr . Chir T. 4, p. 262, Ed. 4.) According to Mr. Pott, the swelling is mostly situated at the middle part of the cord, between the testicle and groin, and is generally of an oblong figure ; whence it has by some peoplebeen compared to an egg, by others to a fish’s bladder. Whe- ther it be large or small, it is generally pretty tense, and consequently the fluctuation of the water within it, not always immediate- ly or easily perceptible. It gives no pain, nor (unless it be very large indeed) does it hinder any necessary action, ft is perfectly circumscribed ; and has no communication, either with the cavity of the belly above, or that of the vaginal coat of the testicle below it. The testis and its epididymis, are per- fectly and distinctly to be felt below the tumour, and are absolutely independent of it. The upper part of the spermatic process in the groin is most frequently very distin- guishable. The swelling does not retain the impression of the fingers ; and when lightly struck upon, sounds as if it contained wind only. It undergoes no alteration from change of the patient’s posture ; it is not affected by his coughing, sneezing, &,c. and it has n» effect on the discharge per anum. The two diseases with which this kind of hydrocele is most likely to be combined, are, an hydrocele of the tunica vaginalis tes- tis, and a true hernia. “ One mark, or characteristic of an hydro- cele of the tunica vaginalis testis is, that it pos- sesses and distends the inferior part ofthe scro- tum; and that thetesticle be iug nearly (though, not absolutely) surrounded by the water, it. very seldom happens that the former can be- clearly and plainly distinguished by the fin- gers of an examiner; whereas, in the en- cysted collection, in the membranes of the cord, the tumour is always above the tes- ticle, which is obvious and plain to be felt below it. “ Another circumstance worth attending to is, that although the fluid in a hydrocele ofthe vaginal coat does so nearly surround the testis as to render it often not very easy to be distinguished, yet the different parts of the tumour have always a very different feel : for instance, in all those points where the vaginal tunic is loose, and unconnected with the tunica albuginea, the tumour is soft and compressible, and gives a clear idea of the contained fluid : but where these two coats are continuous, or make one and the same membrane, and have no cavity between them (which is the case on the middle and posterior part) there will always be found a hardness and firmness very unlike to what is to be found in ail those places where the distance between the two tunics leaves room for the collection of a fluid ; now -the hydro cele of the cord being formed in the mere cellular membrane of it, is the fame tolltf* "4 TlYDPiOCELE. touch in all the parts of the tumour, and feels like a distended bladder through every point of it. u The free state of the upper part of the spermatic process, while the tumour is form- ing below; the gradual accumulation of the fluid, and consequently the gradual growth ot the swelling ; the indolent and unaltering state of it ; its being incapable of reduction, or return into the belly from the first; its being always unaffected by the patients coughing or sneezing; and the uninterrupted freedom of the fecal discharge per anum, will always distinguish it from an intestinal hernia ; and he who mistakes it for an omen- tal one, must be very ignorant, or very heedless.” Mr. Pott met with an encysted hydrocele situated so high toward the groin, as to ren- der the perception of the spermatic vessels very obscure, or even impracticable; but then, the state and appearance of the testi- cle, and the absence of every symptom pro- ceeding from confinement of the intestinal canal, were sufficient marks of the true na- ture of the complaint. Several writers de- scribe this kind of hydrocele, as in fact a common encysted tumour, formed in the cellular substance, between the vas deferens and spermatic vessels. ( Delpech , Precis Elem. dts Mai. Chir. T. 3,p. 464.) Yet, since or- dinary encysted swellings are very difficult to disperse, there is probably some differ- ence between the two affections, at least, if the observation of Mr. Pott be correct, that in young children, the encysted hydro- cele of the cord frequently dissipates in a short time, especially if assisted by warm fo- mentation, and an open belly. If it be not absorbed, “ the point of a lan- cet will give discharge to the water ; and in young children, will most frequently pro- duce a cure : but in adults, the cyst, formed by the pressure of the fluid, does sometimes become so thick, as to require division through its whole length ; which operation may in general be performed with great case, and perfect safety.” Mr. Pott says, in general, because it is most frequently so : though he has even seen this, slight as it may *eem, prove troublesome, hazardous, and fatal. (See Pott on Hydrocele.) The late Sir J. Earle proposed treating this case in the same way as the hydrocele of the tunica vaginalis, viz. by an injection of red wine and water; which method is often successful. (On Hydrocele , p. i 54, edit. 2.) However, the cure of an encysted hydrocele of the spermatic cord, by means of an injection, is generally regarded by modern surgeons, as less certain and advan- tageous, than the excision of a part of the cyst. The operation which is described by Bertrandi, Mr. Hey, Richerand, &.c. consists in cutting down to the cyst, and removing the forepart of it, while the portion, closely attached to the cord, is to be allowed to re- main. For additional observations on this species of hydrocele. (See the First Lines of tltc Practice of Surgery , Vol. 2,p, 121.) hydrocele of the tunica vaginalis. If the quantity of limpid fluid, which na- turally moistens the surface of the tunica albuginea and the inside of the tunica vagi- nalis, be secreted in an undue quantity, or if regular absorption of it be by any mean3 prevented, it will gradually accumulate, and distend the cavity of the latter membrane, so as to form the present species of hydro- cele. The case in which the fluid is sup- posed to descend, either partly or entirely from the cavity of the abdomen, in conse- quence of the communication not being shut up in the usual time, between the ca- vity of the peritoneum and that of the tunica vaginalis, is well known to surgeons under the appellation of a congenital hydrocele ; a disease, of which particular notice has been taken in the 2d Vol. of the last edition of the First Lines of Surgery , 8 vo. Lond. 1820, and to which I shall therefore very briefly advert in this article. Hydrocele of the vaginal coat is a disease from which no time of life is exempt ; not only adults are subject to it, but young children are fre- quently afflicted with it : and infants some- times born with it. (Pott.) And it is re- marked to be common in old men, and per- sons who ride a good deal on horseback. (Delpech Precis Elem. des Mai . Chir . T. 3 f p. 177.) The causes of hydrocele of the tunica vaginalis can scarcely be said to be at all understood ; and when Mr. Pott observes, that whatever tends to increase the secre- tion of fluid into the cavity of that mem- brane, beyond the due and necessary quan- tity, or to prevent its being taken up, and carried off by the absorbent vessels must contribute to the production of the disease, nearly as much is stated, as can be advanced with safety in the present state of our know- ledge. Ruysch had a suspicion, that this hydrocele might arise from a varicose state of the spermatic veins ; but though Mr. Pott acknowledges that these vessels are very frequently found varicose in patients afflict- ed with this disorder, he was unable to pro- nounce what real foundation might exist for the foregoing conjecture, or whether the varicose state of the spermatic veins were a cause, or an effect of the hydrocele. In most instances, the accumulation of fluid takes place without any evident cause ; though, in a few cases, it has appeared to be the effect of a contusion, or of rough long- continued friction of (lie scrotum. The dis- ease is observed to affect persons of the best: health, and most robqst constitutions, as well as others, and its existence seems quite unconnected with dropsy, or debility. In short, it may be regarded as a disease en- tirely of a local nature. As Mr. Pott ob- serves, its production is so slow and gradual, and at the same time so void of pain, that the patient seldom attends to it, until it has arrived to some size. Not but that it some- times is produced very suddenly ; and in a very short space of time attains considerable magnitude. HYDROCELE. 75 In general, at its first beginning, the tu- mour is rather round ; but as it increases, it frequently assumes a pyriform kind of figure, vith its larger extremity downward ; some- times it is hard, and almost incompressible ; so much so, that, in some few instances, it has been mistaken for an induration of the testicle: at other times, it is so soft and lax, that both the testicle, and the fluid surround- ing it, are easily discoverable, it is perfectly indolent in itself ; though its weight some- times produces some small degree of un- easiness in the back. According to Mr. Pott, the transparency of the tumour is the most fallible and uncertain sign belonging to it : it is a circumstance, says he. which does not depend upon the quantity, colour, or consistence of the fluid constituting the disease, so much as on the uncertain thick- ness, or thinness of the containing bag, and of the common membranes of the scro- tum. If they are thin, the fluid limpid, and the accumulation made so quick as not to give the tunica vaginalis time to thicken much, the rays of light may sometimes be seen to pass through the tumour : but this is accident- al, and by no means to be depended upon. The fluid is most frequently of a pale yellow, or straw-colour ; sometimes it is inclined to a greenish cast ; sometimes it is dark, tur- bid, and bloody ; and sometimes it is per- fectly thin and limpid. With respect to Mr. Pott’s remarks on the transparency of the swelling, as a symptom of hydrocele, they are correct, inasmuch as the absence of this sign is no proof, that the disease is not of this nature ; since thickness of the tunica vaginalis, and, as ought also to have been admitted, the opaque quality of the fluid, sometimes prevent the rays of a candle from passing through the swelling. But, on the other hand, it should have been explained by Mr Pott, that when the transpa- rency is present, it is one of the surest marks of this species of hydrocele. It is next noticed by Mr. Pott, that in the beginning of the disease, if the water has ac- cumulated slowly, and the tunica vaginalis is thin and lax, the testicle may easily be perceived ; but if the said tunic be firm, or the water accumulated in any considerable quantity, the tetis cannot be felt at all. In most cases, the spermatic vessels may be distinctly felt at their exit from the abdomi- nal muscle, or in the groin ; which will al- ways distinguish this complaint from an in- testinal hernia. But, in a few examples, the vaginal coat is distended so high, and is so full that it is extremely difficult, nay, almost im- possible, to feel the spermatic cord: and the same kind of obscurity is sometimes occa- sioned by the addition of an encysted hydro- cele of the cord ; or by the case being com- bined with a true enterocele. in a hydrocele of the tunica vaginalis, the swelling is first noticed at the lower part of the scrotum, whence it ascends in front of the testicle and spermatic cord. The pro- gress of the disease is generally so slow, *hat six or even eighteen months elapse, be- fore the tumour approaches the abdominal ring. And, among other characters of the case, are to be noticed the disappearance of the corrugations of the scrotum by the effect of the distention ; inclination of the raphe to the opposite side ; and the possibility of feeling a fluctuation, when (lie fingers of one hand are applied to one side of the tumour, and the surgeon slightly taps with the fingers of his other hand upon an opposite point of the swelling. In the hydroceles of children, the testis occupies a lower situation, than the the same organ in the hydroceles of adult persons, and the swelling passes further up towards the abdominal ring. It is well explained by Mr. Pott, that the tu- nica vaginalis and tunica albuginea, are so inseparably united at the posterior and supe- rior, or rather the posterior and middle part of the tumour, that no fluid can collect between them ; and therefore, the fingers of an intelligent examiner must immediately discover here the firmness and hardness arising from the union of these parts; while in all others, the two membranes being un- connected, and affording a void space for the collection of water, the fluctuation of it will always be distinguishable. “ This (says Pott) must for ever discrimi- nate the simple hydrocele of the tunica va- ginalis from the anasarcons swelling of the scrotum ; from the encysted hydrocele of the cord ; and from the intestinal hernia. The first is every where equal, tumid, and soft; and every where equally receives and retains the impression of the fingers , the second, though circumscribed, not very compressi- ble, and affording the sensation of fluctuation, yet does not pit, and is alike to the touch in all parts of it ; and in the third, if the testicle be distinguishable at all, it is found at the inferior part of the whole tumour.” A collection of fluid in the tunica vagina- lis, complicated with a scirrhous or chronic induration and enlargement of the testicle, is well known under the name of hydro-ca r> cocele ; a case, which should be carefully discriminated from a simple hydrocele, “ one of the marks of the latter being the natural, soft, healthy state of the testicle : and the characteristic of the former being its disea- sed and indurated enlargement.” Mr. Pott does not mean that, in a true simple hydrocele, the testicle is never altered from its natural state. He admits the con- trary, and that it is often enlarged in size, and relaxed in structure, and that the sper- matic vessels are frequently varicose. But, the testicle is never indurated. These two diseases are extremely unlike each other, and require very different treatment. That which would cure a simple hydrocele, would dangerously aggravate the hydro-sarcocele. Mr. Pott observes, that “ it may, and does sometimes become necessary to let out the water from the vaginal coat of a testicle, in some degree diseased ; but this should al- ways be done with caution, and under a guarded prognostic ; lest the patient be not only disappointed, by not having that per- 76 HYDROCELE. manent relief, which, foT* want of better in- formation, he may be induced to expect ; but be also (possibly) subjected to other un- expected inconveniences from the attempt. “ When the disease is a perfect, true, sim- ple hydrocele, the testicle, though frequently somewhat enlarged, and perhaps loosened in its vascular texture, is nevertheless sound, healthy, and capable of executing its proper office ; neither is the spermatic cord any way altered from a natural state, except that its vessels are generally somewhat dilated ; neither of which circumstances are objec- tions either to the palliative or radical cure of the disease. But in those disorders, which in some degree resemble this, the case is different ; either the testicle, or sper- matic cord, or both, bearing evident marks of a diseased state.” According to Richerand, a hydrocele may be known from a sarcocele by the following circumstances: in a sarcocele, the tumour mostly retains the shape of the testicle, being oval and a little flattened at the sides, and its size becomes considerable in a short time, without ascending so near the abdominal ring, as a hydrocele does, when of the same magnitude. A large hydrocele leaves no interspace between that opening and the tumour, so that it is difficult to take hold of, and lift up the spermatic cord ; but, in a sar- cocele, there is always a space between the tumour and the ring, where the cord can be distinctly felt. Lastly, in a sarcocele, the tumour is always opaque, and its weight, in reference to its size, much more consider- able, than that of a hydrocele. ( JYosogr . Chir. T. 4, p. 267, Ed. 4.) The hardness is not a symptom which can be trusted alone, as a criterion of a diseased testicle ; for, when a hydrocele is extremely distended, it ©ften feels so indurated as to deceive prac- titioners of great experience, and a thick- ened, hardened state of the tunica vaginalis may facilitate the mistake. In some instan- ces of hydro-sarcocele, the nature of Ike dis- ease sometimes remains questionable, until the evacuation of the fluid gives the surgeon a fair opportunity of ascertaining the disea- sed state of the testicle. The complication of an hydrocele of the tunica vaginalis with an encysted one of the spermatic cord, may generally be known by the swellings having begun at two differ- ent points, and by a kind of constriction be- tween them. The latter symptom, however, is not infallible, because the tunica vaginalis of a common hydrocele is sometimes more or less contracted at the middle of the tu- mour, which is thus made to appear as if there were two distinct pouches. The size of a hydrocele, and the thick- ness of the tunica vaginalis, are generally 5 , a ratio to the time, which thejdisease has con tinued. Sometimes the latter membrane acquires nearly a cartilaginous hardness; and portions of it have been found in an ossified state ; the only circumstance, in which any free excision of it is now account- ed, necessary. A hydrocele has been known to contain foul* pints of fluid. (V riglel, Jlandbueh der Pract. Jinat. B. 3, p. 388.) METHODS OF CURING THE HYDROCELE OF THE VAGINAL COAT. A hydrocele is by no means a dangerous complaint, though its weight and size are a disagreeable incumbrance, and the patient is always obliged to wear a bag truss, in order to prevent a painful extension of the spermatic cord. Troublesome excoriations are also frequently caused by the friction of the tumour against the inside ot the thigh ; and when the swelling is very large, it draws over itself the integuments of the penis, w hich appears buried, as it were, in the tu- mour, and its functions are seriously inter- rupted. Hence, the greater number of patients are very anxious for relief. “ The methods of cure (says Pott) though various, are reducible to two, (viz.) the pallia- tive, or that which pretends only to relieve the disease in present, by discharging the fluid ; and the radical, or that which aims at a perfect cure, without leaving a possibi- lity of relapse. The end of the former is accomplished by merely opening the con- taining bag in such manner as to let out the water : that of the latter cannot be ob- tained, unless the cavity of that bag be abo- lished, and no receptacle for a future accumu - lation left ; (a proposition, on which the ob- servations of Mr. Ramsden and Mr. Wadd, published since Mr. Pott’s time, have thrown a degree of doubt.) One may be practised at all times of the patient’s life, and in almost any state of health and habit : the other lies under some restraints and prohibitions ; ari- sing from the circumstances of age, constitu- tion, slate of the parts, &.c. “ The operation, by which the fluid is let out, is a very simple one. The only circum stances requiring our attention in it, are, the instrument wherewith we w r ould perform it ; and the place or part of the tumour, into which such instrument should be passed. u The two instruments in use, are the com- mon bleeding-lancet, and the trocar. “The former having the finer point, may possibly pass in rather the easier, (though the difference is hardly perceptible) but is liable to inconveniences, to which the latter is not. The trocar, by means of its cannula, secures the exit of the whole fluid without a possibility of prevention ; the lancet can- not. And therefore it frequently happens when this instrument is used, either that some of the water is left behind, or that some degree of handling and squeezing is required for its expulsion ; or, that the in- troduction of a probe, or a director, or some such instrument, becomes necessary for the same purpose The former of these may in. some habits be productive of inflammation . the latter prolongs what would otherwise be a short operation, and multiplies the ne- cessary instruments ; which, in every ope- ration in surgery, is wrong. To which it may be added, that if any of the fluid be left in the vaginal coat, or insinuates itself HYDROCELE, # into the celte of the scrotum, the patient will have reason to think the operation im- perfect, and to fear, that he shall not reap even the temporary advantage which he expected. The place where this puncture ought to be made, is a circumstance of much more real consequence ; the success of the atiempt, the case, and even some- times the safety of the patient, depending upon it. “ All the anterior and lateral parts of the vaginal coat are loose and detached from the albuginea ; in its posterior and superior part, these two tunics make one ; conse- quently the testicle is, as it were, affixed to the posterior and superior part of the cavity of the sac of an hydrocele ; and conse- quently, the water or fluid can never get quite round it. This being the state of the case, the operation ought always to be per- formed on that pari of the tumour, where the two coats are at the greatest distance from each other, and w here the fluid must therefore be accumulated in the largest quantity ; and never on that part of it where the fluid cannot possibly be. The conse- quence of acting otherwise, must not only produce a disappointment, by not reaching the said fluid ; but may prove, and has pro- ved, highly and even fatally mischievous to the patient. “ After performing this operation, present practitioners content themselves with a bit of lint and a plaster; and if the scrotum has been considerably distended, they sus- pend it in a bag truss ; and give the patient no farther trouble. “ In most people (continues Pott) the orifice thus made heals in a few hours, (like that made for blood-letting ;) but in some habits and circumstances, it inflames and festers ; this festering is generally superfi- cial only, and is soon quieted by any sim- ple dressing ; but it sometimes is so consi- derable, and extends so deep, as to affect the vaginal coat, and by accident produce a radical cure. Mr. Pott has also, seen it prove still more? troublesome, and even fa- tal ; but then the circumstances both of the patient, and of the case, have been par- ticular. “ Wiseman and others have advised de- ferring the puncture, till a pint of fluid has collected. When there is a sufficient quan- tity, however, to keep the testicle from the instrument, there can be no reason for de ferring the discharge ; and the single point on which this argument ought to rest, is this : Whether the absorbent vessels, by which the extravasation should be prevent- ed, are more likely to reassume their office, while the vaginal coat is thin, and has suf- fered but little violence from distention ; or after it has been stretched and distended to ten or perhaps twenty times its natural capacity ; and by such distention is (like all other membranes) become thick, hard, and to idi ? Mr. Pott thinks the probability so much more on the side of the former, that he should never hesitate a moment about Getting out the water, as soon as be found that the puncture could be made securely. And from what has happened within the small circle of his own experience, he is in - clined to believe, that if it was performed more early than it generally is. it might sometimes prevent the return of the disease.’' Ihe foregoing passage deserves to be par- ticularly recollected, because it evidently implies a belief by Mr. Pott himself, that, under certain circumstances, a radical cure may be effected, though the cavity of the tunica vaginalis be not obliterated ; an opinion since promulgated, as I have already said, by Mr. Ramsden, Mr. Wadd, and Mr. Kinder Wood, indeed, itappears probable, that generally when a hydrocele is perma- nently cured, by means of such external ap- plications, as do not excite inflammation, but operate by quickening the action of the absorbent vessels, the cavity of the tunica vaginalis is not destroyed ; and there cau be but little doubt of the same thing, when- ever what is termed a spontaneous cure happens, as it sometimes does in young sub- jects. But, unless the fact were demonstrated by dissection, I should not believe that the cavity is not annihilated, after the comple- tion of a radical cure by any of the methods, calculated to excite inflammation of tho tunica vaginalis and tunica albuginea. The palliative cure should in general be performed at least once on those, who de- termine to undergo a radical one, as it gives an opportunity of examining the state of the testis, and also of permitting the cavity to be filled again only to such a size, as may bethought to be best calculated to en- sure success in any future operation. (Sir J. Earle on Hydrocele, p. 13, ed. 2.) Upon, the subject of performing the opera- tion of tapping hydroceles, Professor Scar- pa gives us some useful cautions. The analogy, which exists between large scrotal herniae and hydroceles of considerable size, led this writer to suspect, that, irr the latter disease, the displacement and separation of the vessels of the spermatic cord from each other might also happen. Careful invest! gations, made upon the dead subject, fully justified the conjecture. In all considerable hydroceles, he found the spermatic vessels so displaced and separated, that the artery and vas deferens were ordinarily situated on one side of the tumour, and the veins on the other. Sometimes these vessels all extend- ed over the lateral parts of the tumour, as far as its anterior surface, principally towards the bottom. It is well known, that in many instances, the operation of puncturing a hydrocele has been followed by a large extravasation of blood within the tunica vaginalis; but Scarpa informs us, that until lately, he was unacquainted with any case of this kind, which was well detailed and authentic enough, to be cited as an example of injury of the spermatic artery in the puncture of a hydrocele. This learned Professor, how- ever, has had such a fact recently commu- nicated to him by Gasparoli, a distinguished surgeon of Pallanza, who, in introducing HYDROCELE. *3 the trocar into the lower part of the swell- ing, had the misfortune to injure the sper- matic artery, and the patient was after- ward castrated. The wound of this vessel Was most clearly proved by the particulars of the case, as detailed in Scarpa’s work, to which I must refer the reader. From the accurate knowledge, (says Scarpa) which we now have upon this pa- thological point, such an accident may be avoided, by observing the rules, which are elsewhere given for opening the sac of a very large scrotal hernia. In this last ope- ration, as well as that of puncturing an old and voluminous hydrocele, care must be ta- ken to introduce the instrument at a consi- derable distance from the bottom of the tu- mour, that is to say, a little below its mid- dle part, and on a line, which would divide the swelling longitudinally into two perfect- ly equal parts. Experience proves, that for the purpose of completely emptying an hydrocele, it is unnecessary to make, the puncture very near the bottom of the tu- mour. The corrugation of the scrotum, and a slight pressure, made by the surgeon’s hand, will suffice for discharging all the fluid contained in the tunica vaginalis, even when the puncture is made at the middle part of the swelling. ( Scarpa , Traits des Hernies, p. 64 — 68.) On account of the lower situation of the testicle in the hydro- cele of a child, than in that of a grown-up erson, these directions of Scarpa will also e of value. RADICAL CURE OF THIS HYDROCELE. Besides the employment of external ap- plications, wherewith a permanent cure has occasionally been accomplished, as related in my other work, six different operations have been practised for the same purpose ; Yiz. incision ; excision ; the application of caustic ; the introduction of a tent ; the employment of a seton, and injecting some stimulating fluid into the cavity of the tuni- ca vaginalis. The principle, on which the success of every plan of this kind is commonly be- lieved to depend, is the excitement of such a degree of inflammation in the tunica vagi- nalis, and tunica albuginea, forming the ca- vity which contains the water, as shall end in a mutual and general concretion of those, membranes with each other, by which it is evident, the receptacle for a future accu- mulation of fluid is completely obliterated. All the above plans are not equally eligi- ble. Some of them, indeed, are now quite exploded ; and some, which are still practi- sed by a few, are not more successful, though certainly more severe, than one, which will be presently recommended ; while others are very uncertain in their ef- fect, as well as painful. Incision. Making an incision so as to lay open the cavity containing the fluid, is the most an- cient method, being described by Celsus. T*aulus jEgineta says, the incision is to com- mence at the middle of the tumour, and be carried to the upper part of it, in a line parallel to the raphe. This incision is on- ly to go through the integuments ; the bag, which contains the water, is then to be opened, and part of the sides of the sac ta- ken away. A director is next to be intro- duced, and a division of the tunica vaginalis made to the bottom of the swelling. The cavity is afterward to be dressed with lint, and healed by granulations. Hildanus, Do- donaeus, Wiseman, Cheselden, Heister, and Sharp, all coincide instating the dangerous and even fatal consequences sometimes fol- lowing this mode. Mr. B. Bell, who pre- ferred this operation to every other one, acknowledges, that he has seen it produce great pain and tension of the abdomen, in- flammation, and fever. Pott observes, that it can never be said to be totally void of danger, and that it bears the appearance of an operation of some severity. This emi- nent surgeon abandoned the method, du ring the last twenty-six years of his life. Severe as it is, it has also been known to fail, as Sabatier and Earle have confirmed. Excision. Albucasis gave the first clear accouut of this operation, though Celsus has certainly mentioned removing some of the sac. White and Douglas used to adopt this me- thod. The latter advises making two in- cisions, so as to form an oval, from the up- per to the lower part of the tumour ; dis- secting off the oval piece of the scrotum, and then making an opening into the sac, and enlarging it with scissors. The tunica vaginalis was next to be entirely cut away, close to where it was connected with the spermatic vessels. The cavity was afterward, filled with lint. Sir James Earle justly noti- ces, that this plan must have been tedious, ex- quisitely painful in the performance, and, as subsequently treated, attended with vio- lent and dangerous symptoms. In modern days, excision is only sanctioned, when the tunica vaginalis is more or less in an ossifi- ed state, for a mere thickening of it does not prevent the success of milder plans of treatment. With respect to a mode of ex- cision, recently proposed by Mr. Kinder Wood, it differs entirely from the ancient method, inasmuch as it is perhaps the mild- est of every plan yet suggested for the ra- dical cure, since it simply consists in punc- turing the hydrocele with an abscess lan- cet, drawing out a little bit of the sac with a tenaculum, and cutting it off. (See Med. Cfiir. Trans. Vol. 9, p. 33.) But, further ex- perience is requisite to determine, whether this very easy plan is as certain as that with an injection. Whether the cavity is oblite- rated or not, as Mr. Kinder Wood himself believes, appears also still questionable. Caustic. Paulus JF.gineta advises destroying the skin with a cautery of a particular form, dissecting off the eschar, and then cauterizing the exposed membrane. Guido di Cauliaco HYDROCELE. •79 is, perhaps, the first who described the ap- plication of caustic for the cure of hydro- cele. Wiseman practised this method. Dionis advises it ; but De la Faye and Garengeot make objections to it. Mr. Else has left the best account of the manner of using caustic. He recommends laying “ a small caustic upon the anterior and in- ferior part of the scrotum, which it is intend- ed to affect, and, if possible, penetrate through the tunica vaginalis.” The objections to the employment of caustic are, its causing an unnecessary destruction of parts, and producing a tedious painful sore. The action of caustic can never be so regulated as to make an opening with certainty through the tunica vaginalis, so that either its application must sometimes be repeated, or else a lancet, or trocar, used after all. Its success is also less sure, than that of an injection ; but, it is preferable to all the other methods, except this latter, the modification of excision proposed by Mr. K. Wood, and, perhaps, the seton. Tent. This is first mentioned by Franco. The operation consists in making ah opening into the tunica vaginalis, and keeping the wound open with a tent of lint, linen, or sponge, so as to make the cavity suppurate, in which the water was contained. Pare, 15 uilleman, Covillard, Ruysch, Heister, and Marini, have all described the plan with some variations, one of which consisted in smearing the tents with irritating substances. Dr. A. Monro senior devised the plan of keeping a cannula in the tunica vagmaiis ; so as to bring on a cohesion ot the parts without suppuration. Fabricius ab Aqua- pendente, however, has made allusion to some surgeons before his time, who used to keep the wound open a few days with a cannula. Mr. Pott tried the cannula, but found it very inconvenient, as its inflexibili- ty hurt the testis whenever the patient mo- ved with inattention, and consequently, he preferred a tent, or bougie, though he speaks of the plan as a very uncertain one. Of late, Baron Larrey, in consequence of having seen several instances, in which the symptoms, following the use of an injec- tion, were violent, and one case, in which a fatal peritonitis was produced, has recom- mended exciting the necessary degree of inflammation by keeping a short piece of an elastic gum catneter in the puncture, which instrument also serves afterward to let any fluid escape from the tunica vaginalis. (Mem. de Chir. Militaire, T. 3, p. 109, &pc.) This author, of course, speaks of the plan as having fully answered his expectations ; but, 1 much doubt whether it has any parti- cular superiority over several of the former methods of employing the tent; methods, which the wisdom, arising from experience, has long since rejected', Seton Was first mentioned by Guido di Cauliaco, in 1498, as a means of curing the hydrocele. In modern times, Pott preferred it to everv other method, if we except injection, of which, according to Sir J. Earle, he express- ed his approbation before his decease. Mr. Pott found, that the best mode of making the seton was as follows. He employed, three instruments: the first was a trocar, the cannula of which was about one-fourth of an inch broad. The second was what he called the seton-cannula, which was made of silver, was just small enough to pass with ease through the cannula of the trocar, and five inches long. The third instrument was a probe six inches and a half long, having at one end a fine steel trocarppint, and, at the other, an eye, which carried the seton. The seton consisted of so much white sewingsilk, as would just pass easily through the cannu- la, arid yet fill it. The thickness of the seton, however, was not so great in the lat- ter part of his practice. Having pierced the inferior and anterior part of the tumour with the trocar, withdrawn the perforator, and discharged the water, Mr. Pott used to pass the seton-cannula throm h that of the trocar, to the upper part of the tunica vagi- nalis, so as to be felt there. The probe, armed with the seton, w r as next conveyed through the latter cannula, a id its point pushed through the upper part of the tunica vaginalis, and scrotum. The silk was then draw n through the cannula, until asulficient quantity was brought out of the upper orifice. The two cannula being withdrawn, the ope- ration was finished. Injection. Dr. Monro attributes the first use of injec- tions for the radical cure of hydroceles to an army-surgeon of his own name, who em- ployed spirits of wine. This produced a cure, but the inflammation was so violent, that he afterward tried a milder injection, which consisted of wine. However, Lam- bert, in his (Euvres Chir. published at Mar- seilles early in the seventeenth century ad- vised injecting a solution of sublimate in lime water, and he has related cases of suc- cess. Mr. 5 . Sharp also made trial of spirit of wine, which cured the hydrocele, but not. without causing dangerous symptoms, and two subsequent abscesses in the scrotum. (Operations of Surgery.) Douglas, Le Dran, and Pott, all disapprove of injections in their works ; though Sir James Earle informs us, that the latter lived to alter his opinion on the subject. The violence of the inflammatory symp- toms, consequent to the first employment of injections for the radical cure of hydroceles, arose from the fluids used being too irrita- ting. Sir James Earle, at last, preferred wine for several reasons. He found, that it had been used with success in France ; its strength is never so great as to render it unsafe ; and it may be readily weakened. This injection, in short, produces less pain than any other mode of cure, does nothing more than is intended, and is as certain as any plan. I have commonly used ('says Sir James HYDROCELE; 80 Earle) about two-thirds of wine to one- third of water; if the parts appeared in- sensible, and no pain at all was produced by the first quantity thrown in, I have with drawn the syringe, and added to the propor- tion of wine ; on the contrary, if the corn- plaint was recent, and the parts irritable, I have increased the proportion of water, so that 1 have hitherto been principally guided by the degree of sensation, which the pa- tient has expressed. I have lately used pure water mixed with wine, and found it answer as well as when astringents were added/’ ( P • 103, Treatise on the Hydrocele, Ed. 2.) In the preface, the author says, that he has long disused the pipe with a stop-cock, which he once employed, on account of not being well able to spare a hand, during the operation, to turn it, and its consequently being found awkward. A pipe, one end of which is made to fit into the cannula ot a trocar, the other adapted to receive the neck ot an elastic bottle, with a valve, or ball, in the centre of the pipe to permit the en- trance, and prevent the exit, of the injection, will be found infinitely more convenient and useful. (Earle.) When the hydrocele is very large, Sir James recommends simply letting out the fluid, and waiting till the tu- mour acquires a more moderate size before attempting the radical cure by injection. It appears from Sir James Earle’s interest- ing cases, that a cure may be accomplished in this manner, even when the tunica vagi- nalis is considerably thickened. The follow- ing is the common mode of operating ; the hydrocele is to be tapped with a trocar at its anterior and inferior part, and, when the whole of the fluid is evacuated, the cavity of the tunica vaginalis is to be distended to its former dimensions with the above injection. Thfs is to be allowed to remain in the part about five minutes, upon the average, after which it is to be discharged through the can- nula. The patient usually feels some pain in the groin, and about the kidneys, on the injection being introduced : which symptoms are rather desirable, as they evince that the stimulus of the fluid is likely to have the wished-for effect of exciting the necessary degree of inflammation. This plan, which was brought to a high pitch of perfection by the late Sir James Earle, may be deemed almost an infallible means of obtaining- a permanent cure; and being, at the same time, mild, is mostly preferred in England, France, and Germany. The treatment after the operation is exactly like that of the common swelled testicle, (see Hernia Humoralis,) consisting of the use of fermentations, poultices, leeches, saline purges, and, above all, of a bag truss for keeping up the scrotum. There is a particular case, that has been called the congenital hydrocele, by which is implied a collection of water in the tunica vaginalis, w ith a communication between the cavity of this membrane and that of the peri- tonaeum. Desault used to cure this disease, by a red wine injection. After the protruded viscera had been returned into the belly, and w f hile the opening between that and the in-' side of the tunica vaginalis was carefully compressed and closed 1 by a trusty assistant, Desault, after letting out the water in the common way, used to throw in the injection. The method, it is said, succeeded without causing the perilous consequence, one might a priori expect, viz. inflammation of the peritonaeum. This kind of hydrocele has not been des- cribed by many writers. The case is easily distinguished by the fluid being capable of being pushed into the belly. According to Desault, this disease admits of a cure by in- jections, care being first taken to press the upper part of the cord, so as to keep the in- jection from coming into contact with the peritonaeum. A successful instance of this practice is related, by which a boy was cured both of a congenital hydrocele and hernia. The patient was nine years old, and had in his scrotum, ever since he wa3 born, a fluctuating semi-transparent tumour, which was free from pain, of the size of a large egg, and disappeared when compressed^ and in a horizontal posture. (See (Euvres Chir dc Desault, T 2, /v. 442.) This subject of congenital hydrocele has been more particularly considered in my other work. One caution it is necessary to offer, before taking our leave of this subject ; it has some- times happened, duringthe operation, thatthe cannula has slipped out of the tunica vaginalis, and its inner mouth become situated in the substance of the scrotum, in which event the operator, if he persists in propelling in the injection, will fill the cellular texture of the part with a stimulating fluid, which may cause sloughing, and other unpleasant symp- toms, wdtbout entering the cavity of the tu- nica vaginalis, or producing a radical cure of the hydrocele, which, however, I have known happen from this cause, as I have elsewhere related. (See First Lines of Sur- gery, Hoi. 2.) When such an accident hap- pens, it is better to defer the operation, till a sufficient quantity of ffuid has collected again. Hydroceles have been cured by ap- plying to the scrotum a solution of muriate of ammonia in vinegar and water (Kcate.) But, the application frequently creates. a good deal of pain and irritation, and does not often succeed, to say the best of it. (Earle.) Distending the tunica vaginalis with air, cold water, or even the fluid discharged, has sometimes effected a radical cure. (See Supplement to Ploucquct, Tub. 1S14, p. 103.) For many other important remarks, con- cerning hydroceles, I am obliged to refer to the 2d vol. of the last edition of the First Lines of the Practice of Surgery, 1S20. Monro on the Tumours of the Scrotum in the Ediab. Med. Essays, Vol. 5. John Douglas. .1. Trea- tise on Hydrocele, 8vo Loud. 1755; and Answer to Remarks on that Work , 8vo. Loud. 1758. Pott on the Hydrocele ; Else on the on the Hydrocele, 8vo. Land 1770; and the Works of Joseph Else, 8vo. Loud. J782. W. Dense , on the Different kinds of Hydrocele, 8 vo. London. 1798. Kcate ; B. Bell, on Hy'- HYDROPHOBIA 31 i i/occlc , Sarcocele, fyc. 8 vo. Edinb. 1704. Sir James Earle, Treatise on llie Hydrocele , 2 d Ed. Si’o. Land. 1803. Schreger Chirurgisches Versuchc, B. 1, 8 vo. JYumberg, 1811 , a cure effected by the injection of air, p. 30G. Ber trandi. in Mem. de l' Acad. de Chir. T. 3; and in Traitato delle Operazioni di Chirurgia, Nizaa, 1763. Desault , Remarques, fyc. sur diverses especes d' Hydrocele. (Euvres. Chir. T. 2. S. Sharp's Treatise on the Operations, and his Critical Inquiry. J. Howard , Obs. on the Method of Curing the Hydrocele by Means of a Seton, Svo. Loud. 1783. Sabatier , Mldecine Optraloire , T. 1, Ed. 2. Scarpa, Traili des Hernies, p. 64, fyc. Larrey , Me- moir es de Chir. Militaire, T. 3, p. 400, 4'C. T. Ramsden , Practical Observations on the Sclerocele, §'C. Svo. Lond. 1811. IV IVadd, Cases of Diseased Bladder and Testicle, 4to. Lond. 1815. Kinder Wood, some Observations on. the Cure of the Hydrocele of the Tunica Vaginalis, without procuring an Obliteration of the. Sac , in Med. Chir. Trans. Vol. 0. p 38, Svo. Lond. 1818. * H YD R O P H 0 B 1 A . (from vJcep, water, and poSoj, fear. A dread of water.) This being, for the most part, a striking symptom of the fatal indisposition which results from the bite of a mad dog, and some other animals af- fected in the same way, the disease itself lias been named Hydrophobia. Some have used the more general term, hygrophnbia, from vygpv, liquid. But strong objection has been made to both these terms, because de- rived from a symptom, which does not ex- clusively belong to the disease, nor constant- ly exist in it. The old writers, as we learn from Caelius Aureliapus, used the terms acrophobia, or a dread of air, and pantephobia, or a fear of all things. Since the impression of cold air sometimes excites terror, and the disor- der is marked by a singular degree of gene- ral timidity qnd distrust. Others called it phobodipson (S'i^W) signifying thirst,) because the patient is thirsty, yet fears to drink. Se- veral modern authors, however, objecting to any appellation expressive only of one symp- tom, denominate the disease rabies, and rabies catiina, or canine madness. The French call it la rage. With respect to hydrophobia, orthe dread- ful mdisposjtion produced by the bite of a dog, or other animal, affected with rabies, or by the application of some of the secretions of such animal to a part of the body, the first allusion to it to be found in authors, is that made by Aristotle, (Hist. Animal, lib. 7, cap. 22 ;) but he could have had but very erroneous notions upon the subject, since he sets down man as incapable of receiving the distemper from the bite of a rabid dog. With respect to a name for the disorder, as the patient does not commonly betray any tendency to fury, While the dread of water is really a customary attendant on the com- plaint, the terms rabies and la rage seem strictly even more exceptionable than the word hydrophobia. At the same time, in Order not to imbibe confused notions, what- ever name be thought fittest for the illness Vol. If ~ 11 arising in (he human subject from the bite of a mad dog, and some other animals simi- larly affected, it is necessary to understand well, that hydrophobia, in the sense of a horror of water, or other liquids, is an occa- sional symptom of many diseases, and nei- ther exclusively confined to the indisposi- tion caused by the bite of a rabid dog, or certain other animals, nor even constantly attendant upon it. And, with the same view of avoiding perplexity, all hydrophobic complaints may be arranged in two general divisions: 1. The first, comprising, all cases not ascribable to the bite of a rabid animal, or the application of some of its secretions to a part of the body. 2. The second, comprehending the ex- amples preceded by one of those occurren ces. The eases included in the first of these divisions are subdivided into the symptomatic and idiopathic, or spontaneous. By symptom- atic hydrophobia is understood an aversion or dread of liquids, presenting itself as an occasional symptom of various diseases, as of certain inflammatory, febrile, and nervous disorders, hysteria, epilepsy, injuries of the brain, (Trecourt, in Recueil Periodique , tyc. T. 6 ; Acta Nalurce Curios. Vol. 2, Obs. 205,) ■ the operation of particular poisons; (Filler- may, Traite des Mai. JYer reuses, T. 1, p. 90 ; Harles i/ber die Hundiswuth, Frankf. 1809; Schmiedel, Diss.de Hydrophobia exusufruc- tuum fagi, Erlang. 1762, fee.) gastritis, pneumonia, hepatitis, angina, fcc. &c. In many of the instances of symptomatic hydrophobia, the aversion, or dread of fluids, occurs on the same day as the cause upon which it depends, or a few days afterward ; and, for the most part, may be cured with the disease which has given rise to it, or eVtn independently of it. On the contrary, the hydrophobia from the bite, or infection of a rabid animal, does not come on till a long time after the occurrence of the cause, and, when once formed, has hitherto proved, incurable, or very nearly so. Whatever analogy, therefore, may be imagined to exist between symptomatic hydrophobia and ra- bies, they differ essentially in their causes, progress, degree of curability, and also in the treatment required. (See Did. des Sciences Med . T. 4, p. 3S.J Spontaneous, or idiopathic hydrophobia, denotes the questionable form of the com- plaint, sometimes supposed to be induced by violent mental commotion, anger, fright, 6ic. uupreceded by any other primary dis- ease, to which it can be referred as a symp- tom. Numerous facts upon record leave no doubt concerning the reality of symptomatic hydrophobia ; but, perhaps, none of the cases adduced by Raymond (Mem. de la Sor , Royale de Med. T. 2, p. 457,) Roupe (JYova Ada Physico-Med. T. 4.) or Pouteau ( Essai sur la Rage, Lyons, 1763,) in proof of the possibility of a spontaneous idiopathic form of the disease in the human subject, aro sufficiently unequivocal to remove all susfi' HYDROPHOBIA. 82 cion, that the complaint either had been preceded by another primary disease {Did. des Sciences Med. T. 22, p. 333,) or had been the result of an unobserved, or forgotten occasion, on which the infection wasi re- ceived from handling a dog, or cat, never suspected at the time to be affected with rabies. Here a wrong conclusion is the more apt to be drawn, in consequence of the disease being communicable without any bite to fix the patient’s attention, and not commencing sometimes for months after the unnoticed receipt of the infection. Thus, Francis Stannier died, in Nov 1787, with symptoms of hydrophobia, though it was not known that he had ever been bitten by a mad dog, ( Loud . Med. Journ. Vol. 9,p. 256 3 ) yet, what safe inference can be drawn from this case, when the above-mentioned circumstances are recollected, and it is known that the man was often drunk, and in the streets at night ? These and other considerations even throw 7 a doubt upon a part of the cases, recorded as instances of symptomatic tetanus, and they lead the generality of the modern writers ta incline to the sentiment of Dr. .1. Hunter, that a disease, similar in its nature to what is pro- duced by the bite of a mad dog, never arises spontaneously in the human subject. (See Trans, of a Soc.for the improvement of Med. and Chir. Knowledge , Vol.\,p. 299 — 303.) Many of the symptomatic cases, however, or those in which more or less aversion, or dread of liquids, is evinced as an effect of another disease, are too well authenticated to admit of doubt. In the Did. des Sciences Mid. T. 22, art. Hydrophobie, may be found a great deal of information likely to interest such readers as wish to follow up the subject of the symptomatic forms of the disease. However, in looking over some of the cases there detailed, a suspicion wdll sometimes arise in an intelligent mind, that the disorder was mistaken ; for it will be noticed, that sometimes pain shooting up the limbs prece- ded the general indisposition, while the rapidity of the disease, arid the appearances found on dissection, corresponded precisely to what is usually remarked in hydrophobia. In particular, one patient is described as a man habituated to drinking, and, as a sports- man, to dogs also ; he died on the third day, and, on dissection, the stomach and intes- tines were found inflamed, and even gan- grenous in several places, the (Esophagus and lungs also participating in the inflam- mation. ( Commerc . Litter. JVoremb. 1743, Hebd. 5.) Animals of the dog kind, including the wolf and the fox, are most frequently the subject of rabies ; and certain writers have maintained, that, although it may be recei- ved and propagated by other animals, yet it always originates in some of the canine race. {Hillary on Diseases of Barbadoes, p. 246.) However, it is asserted, that the disease sometimes originates spontaneously in cats, that is to say, without their having been previously bitten by another rabid animal ; but the moderns do not incline to the belief. that it ever has been known to commence in this manner in other animals, though such an assertion is made by Ccelius Aurelianus, Porphyrius, Avicenna, Valeriola, Stafpart- vandei Wiel, he. not only with respect to man, but horses, asses, camels, hogs, bul- locks, bears, monkeys, and even poultry. (See Diet, des Sciences Mid. T. 47, p. 45.) It is interesting to inquire, what animals are capable of communicating rabies, and what animals of receiving it ? As far as our knowledge yet extends, it appears that ani- mals of the canine species, with perhaps those of the feline race, are the only ones in which this disorder ever arises spontane- ously, and they may transmit it to animals of their own kind, to other quadrupeds, and to man. The experiments made by Dr. Zincke, tend to prove also that birds, at least the common fowl, may have the dis- ease communicated to them. (Neue Jin - dchten der Hundswuth , fyc. 8 vo, Jena, 1804.) But, though it be w ell known, that animals of the dog and cat kinds can propagate the disorder, it is not settled whether it can be communicated by other animals. In a me- moir read to the French Institute, M. Hu- zard explained that herbivorous quadrupeds, affected with rabies, are incapable of trans- mitting the disease ; a position subsequently confirmed by additional experiments and observations made in the veterinary school at Alfort. Professor Dupuy could never communicate the distemper to cows and sheep, by rubbing their wounds with a sponge, which animals of the same class, already labouring under the disease, had had in their mouths ; though the same ex- periment, made with a sponge, Avhich had been bitten by a rabid dog, propagated ra- bies by a kind of inoculation. Dupuy has likewise seen, among several flocks, sheep affected with rabies, yet the distemper was never communicated by them to other sheep, notw ithstanding the latter were bit in parts stripped of wool. Dr. Gillman inoculated two rabbits with the saliva of a rabid pig ; but the disease W'as not communicated to them. (On the Bite of a Rabid Animal, p. 38.) On the other hand, Mr. King, of Clifton, is stated to have communicated rabies to a fowl, by inoculating it with the saliva of an ox, which had just fallen a victim to the disease. (J. Ashburner , Diss. de Hydrophobia , p. 29 ) The author of the article Rnge (Did. des Sciences Mid.) observes, respecting this singular case, that, as it is accompanied with no details, doubts must remain, whether the fowl actually died of rabies. As for some extraordinary cases, in which the disease is alleged to have been com- municated to the human subject by the bites of birds, or injuries done with the claws of animals, they are generally dismissed by modern writers, with the inference, that the complaint thus transmitted was not true hydrophobia or rabies. This conclusion is made, with respect to the cases of this kind, reported by Ccelius Aurelianus and Bader, and the notorious example mentioned by A Baccius of a gardener, who died of the bite HYDROPHOBIA. of a cock, which, according to some, was rabid, according to others, merely enraged. Hildanus also details an instance, in which a young man was scratched on the great toe by a cat: and, some months afterward, was attacked with hydrophobia ( Obs Chir . Cent. 1 , Obs. 16 ;) but, as a modern writer observes, if the patient were really affected with rabies, it is conceivable that the cat’s claw, with which the scratch was made, might have been wet with the animal’s saliva. (Did. des Sciences Med. T. 47, p. 47.) Another question of considerable import- ance is, whether hydrophobia, that is to say rabies, can be communicated from one hu- man being to another ? — or whether, in man, the disease is infectious or contagious ? Many attempts have been made, in vain, to communicate the distemper to several kinds of animals, by inoculating them with the saliva of patients who had perished of the disease. These experiments were made in this country by Gauthier, Vaughan, Babing- ton, &c.; but no infection was the conse- quence. In France, Giraud inoculated several dogs with the saliva of a man in the convulsed stage of hydrophobia, but none of them afterward took the distemper. ( Bosquillon , Mim. sur Its Causes de l' Hydro- phobie, in Mini de la Soc. d’ Emulation, 5 me annie.) M. Girard, of Lyons, collected some of the frothy saliva the instant it was dis- charged from a patient’s mouth, and he in- serted some of it into eight punctures, made on the inside of a dog’s four legs ; yet, six months after this inoculation, the animal had not suffered the slightest inconvenience . (Essai sur le Tetanos Rabiens, p. 29.) A similar experiment was made on three dogs by M. Paroisse, who kept the animals be- tween three and four months afterward, during all which time they continued quite unaffected. ( Bibl . Med. T 43.) Dr. Bezard published the following ex- periments : — Pieces of the flesh of a person who had died of hydrophobia, were smeared with his saliva, and given to a dog ; another dog was suffered to eat the salivary glands ; and a third, the sides of a wound. In three other dogs, incisions were made, the cut parts were then inoculated, and sewed up. Not one of these six animals became affected with rabies. (See Mim. et Obs. lus b la Soc. Mid. Philanthropique, premiere annie , 1807, V • IV.) The preceding experiments only furnish negative results : but one, to which we shall now advert, tends to establish a contrary opinion. On the 19th June, 1813, in the Hotel-Dieu, at Paris, Magendie and Brescht t took some of the saliva of a man, who died a few minutes afterward of hydropho bia, and, by means of a bit of rag, they conveyed this saliva to the short distance of twenty paces from the patient’s bed, and in- oculated with it two healthy dogs. One of the dogs became rabid on the 27th of July, an ' rat two others, one of which was attack- ed with complete rabies on the 26th of August. (C. Burnout; see Collect, des Theses, in 4 to. de la Faculty de Paris , 1814.) It is 83 remarked, in the work, from which I have collected these particulars, that the foregoing is one of the best authenticated experiments on the subject ; for, in addition to the con- sideration of the talents and characters of the experimeners themselves, the facts were witnessed by numerous medical stu- dents. And, notwithstanding the objections which have been urged against the account, (see Journ. Gen. de Mid. T. 52, p. 13 ) the main points are declared to be entitled to credit. (See Did. des Sciences Mid. T. 47, p. 4-h With these relations, it is proper to notice certain cases, too credulously promulgated as proofs of the possibility of the disease be- ing communicated from one human being to another. Neither the instance of the maid-servant, who died merely from seeing her mistress vomit, while labouring under hydrophobia (Mich. Ettmuller, Op. Med. T. 2 ;) the case of the peasant’s children, which, all died on the seventh day , as is alleged from embracing their dying father; the example of a woman contracting hydrophobia from her husband, as detailed by Mangor (Acta Soc. Reg. Hafniens. V. 2, Obs 32, p. 40S ;) nor other cases of a similar tenor ; are now regarded as proving any thing more than that the patients, supposed to have caught the disease by contagion, fell victims either to violent affections of the mind and nervous system, or illnesses accidentally taking place soon after the death of a near relation or mistress. It is clear enough also, that some of the cases were, at most, only instances of symptomatic hydrophobia. With regard to another opinion, that the bite of a man, or other animal, when merely enraged, may bring on hydrophobia, it is now entirely discarded as erroneous. The cases in support of it, recorded by Cl. Pou- teau, Mangetus, Malpighi, Zuinger, Le Cat, &c. when critically examined, only prove that the patients were affected with tetanus, or symptomatic hydrophobia, not arising from any infection; for neither the mode of attack, nor the progress of the symptoms, in any of the examples which are related with sufficient minuteness, lead to the infe- rence, that the patients actually died of rabies. (See Did. des Sciences, Mid. T. 47, p. 49.) Wrong notions of a very dangerous ten- dency, have been generally entertained, in regard to the diseasb, as it appears in the canine race. The writer of the article Dog , in Dr. Rees’s Cyclopasdia, appears to have had extensive opportunities of observing the disorder in dogs, having paid attention to more than two hundred cases. From his remarks, I have collected the following in- formation. The peculiar symptom which character- izes the complaint in the human subject, has been applied to the disease in the dog, end has occasioned it to be called by the same name, hydrophobia. This is a palpable mis- nomer ; for, in no instance, does there ever exist any dread of water; on the contrary,, dogs are in general very greedy after it. 84 HYDROPHOBIA. Such unfounded supposition has often con- duced to a very fatal error : for, it being the received opinion, that no dog is mad who can lap water, many persons have been lulled into a dangerous security. Anotner equally false and fatal idea has prevailed, that every mad dog must be wild and furi- ous ; but this is so far from being true, that, in the greater number of instances, there is very little of that wild savage fury that is expected by the generality of persons. H Hence,” says this author, u as it is evi- dent that the term hydrophobia, characteri- zing the affection in the dog, is a misnomer, so it is evident that the term madness is equally so. In no instance have 1 ever ob- served a total alienation of the mind ; in very few have the mental faculties been disturbed. The disposition to do mischief is rather an increased irritability than ab- sence of sense; for, in most instances, even those that are furious, they acknowledge the master’s voice, and are obedient.” The symptom, which is most frequently first ob- servable in a rabid dog, is a certain peculia- rity in his manner; some strange departure from his usual habits. In a very great num- ber of instances, the peculiarity consists in a disposition to pick up straws, bits of paper, rags, threads, or the smallest objects, which may happen to be on the iloor. This is said to be particularly common in small dogs. ti Others again show an early peculiarity by licking the parts of another dog. In one instance, the approach of the disease was foretold by our observing a very uncommon attachment in a pug-puppy towards a kitten, which he was constantly licking ; and like- wise the cold nose of a healthy pug that was With him. An attachment to the sensation of cold appears in many cases, it being very common to observe them (the dogs) licking the cold iron, cold stones, &.c. Some dogs, early in the disease, will eat their own ex- crement, and lap their own urine. An early antipathy to strange dogs and cats is very commonly observed, but particularly to cats. As the disease advances, the affected dogs bite those with which they are domesticated, and, lastly, the persons around ; but, except in a moment of irritability, they seldom attack the human subject. The irritability that induces them to bite is very strong, but is devoid of wildness. It is more like pee- vishness than fury. A stick held up at them always excites their anger in a violeni de- gree, and throughout the disease there is generally a wonderful impatience of control, and the animals are with great difficulty frightened. (See art. Dog, in Reefs Cyclopes - dia.) To this passage the following remarks may be added : — Dr. John Hunter calculated, that out of every dozen of rabid dogs, about one evinces no particular tendency to bile. That these animals, and wolves also, have no particular dread of fluid, is proved by facts. Thus, a rabid wolf, at Frejus, swam across several rivers. ( Dariuc , Recucil Pe- riod. d'Obs. Vol. d.) Duboueix has seen tnad dogs drink without difficulty, and plen- tifully. ( Hist, de la Roc. de Med. an. 1783.) Rabid animals will sometimes eat as well as drink. Thus the wolf which bit so many persons at Meyne, in 1718, was found in the morning devouring a shepherd’s dog. And Dr. Gilman speaks of a dog, which was not deemed rabid, because it eat and drauk well ; but, as it seemed indisposed, it was kilted, though not before it had bit a man, who fell a victim to hydrophobia. (On Ike Bile of a Babid Animal, p. 15.) When a dog bites a person, it should not be immediately killed, but merely chained up, because, by destroying it at once, the possibility of ascertaining whether it was rabid is prevented, and great alarm is thus kept up in the mind of the wounded person and his friends. If the animal be affected with rabies, it will perish in a few days. At the veterinary school at Alfort, when a dag has been bit, it is usual to chain the animal up, for at least fifty days, before it is resto- red to its master, about six weeks being considered the period when a dog generally becomes rabid after being bitten. For additional details, relating to the dis- ease as it appears in the dog, I must refer to the above-mentioned paper. Enough, I hope, has been said to make the reader aware, that mad dogs are not particularly characterized by an inability to lap water, or any degree of fury. These animals, when actually affected with rabies, from their quiet manner, have even not been suspected of having the disorder, and have been allow- ed to run about, been fondled, and even slept with. (See Mem oj Swedish Acad , 3777.) The causes of this peculiar distemper in dogs are at present unknown, and little more than conjecture prevails upon the sub- ject. It is not positively known whether rabies sometimes originate spontaneously in these animals, though 1 believe this opinion is at present gaining ground; or whether, like small-pox in the human species, it is propagated only by contagion. That the disease is frequently imparted in conse- quence of one dog biting another, every body well knows. Yet there are many in- stances in which this mode of propagation cannot be suspected. Several facts render it probable, that, among dogs, the disease is often communicated by contagion It is observed, that, in insular situations, dogs are seldom affected, and this circumstance is ascribed to such animals being in a kind of quarantine. The celebrated sportsman, Mr. Meynell, secured his dogs from the ma- lady by making every new hound perform a quarantine before lie was suffered to join tht j:ack. (See Trans. for the Improvement of ed. and Chir. Knowledge, Vol. I .art. 17,.) Great -heat was very commonly supposed to be an exciting cause of the disease in dogs ; but without much foundation. “ A very Dot climate, or one exposed to the extremes ol heat and cold ; a very hot and dry season ; feeding upon putrid, stinking, anu magotty flesh; want of water; worms in the kid- neys, intestines, brain, or cavities of the HYDROPHOBIA. tod nose,” are set down by Boerhaave as causes of the disease. {Aphorism, 1134.) We learn from Dr. J. Hunter, that, in the hot islund of Jamaica, where dogs are exceed- ingly numerous, not one was known to go mad during forty years. ( Trans, for the Im- provement of Med. Knowledge, loc. cit.) Cold weather has also been set down as condu- cive to rabies among the canine race, as is suggested, because the ponds being frozen, these animals cannot quench their thirst. (Le Roux.) That neither of these senti- ments about heat and cold being the cause of the origin of the disease in dogs is cor- rect, will be manifest enough to any body who has patience to look over the volume of the Mem. de la Soc. Royale de Med. devo- ted entirely to the consideration of rabies $ and, from the investigations of M. Andry, (Rechcrches sur la Rage , 8 vo. Paris, 1780,) it appears that January, the coldest month in the year, and August, the hottest, are those which furnish the fewest instances of hydro- phobia. On the contrary, the greatest num- ber of rabid wolves is in March and April ; and that of dogs, affected with spontaneous rabies, in May and September. According to Savarv, dogs never go mad in the Island of Cyprus, nor in that part of Syria which is near the sea ; and Volney assures us that these animals enjoy the same fortunate exemption both in the latter country and in Egypt. ( Voyage in Syrie, T. 1.) The traveller Brown also declares, that, in Egypt, they are never, or very rarely, attacked with rabies. “ Although (says Baron Larrey) hydro- phobia is more frequent in warm than tem - perate climates, it is not observed in Egypt, and the natives assured us, that they knew of no instance in which this disease had manifested itself, either in man or animals. No doubt this is owing to the species and character of the dogs of this country, and their manner of living. “ It is remarked, that the Egyptian dogs are almost continually in a state of inaction; during the day, they lie down in the shade, near vessels full of fresh water prepared by the natives. They only run about in the nighttime ; they evince the signs and effects of their love but once a year, and only for a few instants. They are seldom seen cou- pled. On our arrival, there was a vast num- ber of these animals in Egypt, because they were held, like many others, in great vene- ration, and were never put to death. They do not go into the houses; in the day time they remain at the sides of the streets, and they only wander into the country at night, in orderto find any dead animals which hap- pen to be unburied. Their disposition is meek and peaceable, and fhey rarely fight with each other. Possibly all these causes may exempt them from rabies.” (Larrey in Mim. de Chir. Militaire, T. 2 ,p. 226.) This observation, about the exemption of the Egyptian dogs from rabies, is a very ancient one, having been made by Prosper Alpinus, (Rer. JEgypliarum, lib. 4, cap. 8.) According to Barrow, (he dogs in the vici- nity of the Cape of Good Hope, and in Caf- fraria, very rarely go mad. (Travels into the Interior of Africa.) Several authors assert, that rabies never occurs in South America. {Bill. Raisounte, 1750. Van Swieten Com- ment iiAphor. 1129, Portal fyc.) L. Va- lentin declares, that it is exceedingly rare in the warm regions of America, but common in the northern part of that continent. ( Journ . Gen. de Med. T. 20.) Dr. Thomas, who resided a good while in the West Indies, never saw nor heard of a case of rabies there, (Practice of Physic ;) and Dr. B. 4 Moseley states that the disorder was not known in those islands, down to 1783. On the other hand, the disease sometimes hap- pens in the East Indies, though not with such frequency as at all to justify the doc- trine about heat being the cause of its pro- duction. The silence of Hippocrates proves, that in his days hydrophobia must have been very rare in Greece ; and, as the disorder is not mentioned in tht Scrip ores, an inference may be made, that it could not be so com- mon in the hot tracts of the globe, inhabit- ed by the Hebrews, as in the temperate cli- mates of Europe and A merica. Neither can the sentiment be received as correct, that rabies is more frequent in the north than- in the temperate parts of Europe ; for De la Fontaine particularly notices how extremely rare it is in Poland. (Chif. Med. Abhandl. Breslau , 1792.) The disease is reported to be very common in Prussian Lithuania ; but mad dogs are seldom or never heard of at Archangel, Tobolsk, or in the country north of St. Petersburg. In Mr. Meynell’s account, which was communicated to him by a physician, it is asserted, that the complaint never arises from hot weather, nor putrid provisions, nor from any cause except the bite ; for, however dogs have been confined, however fed, or whatever may have been the heat of the season, the disorder never commenced, without a possibility of tracing it to the preceding cause, nor was it ever introduced into the kennel, except by the bite of a mad dog. (See art. Dog, in Rees's Cyclopedia.) Dr. Gillman endeavours to prove, that the disease in dogs is probably excited inde - pendently of particular climates, of putrid aliment, of deficiency of water, of want of perspiration, or, of the worm under the tongue, to which causes it has been at different times ascribed, and he expresses his belief, that it originates somewhat like typhus in the human subject, and is not always produced by inoculation, or by means of a bite. He thinks that it maybe occasionally brought on by the confinement of dogs, without exercise, in close and filthy kennels ; and that the success of Mr. Treval- yan, as related by Dr. Bardsley, in clearing his kennel of the disease, by changing even the pavement, after other means of purifica- tion had failed, affords presumptive evidence in favour of the opinion; and, consequently, this author thinks, that the method of qua- rantine, adopted by Mr. Meynell, and recom- mended by Dr. Bardsley, on the supposition, 86 HYDROPHOBIA. that the disease originates exclusively from contagion, will not be a sufficient prevent- ive alone ; and he infers, from some facts, reported by Mr. Daniel, that the poison sometimes lies dormant in dogs fpur, five, and six months ; and, consequently, that the period of two months is not a sufficient quarantine. (See Gillmari’s Diss. bn the Bite of a Rabid Animal.) In opposition, however, to some of the sentiments contained in the foregoing pas- sage, it should be known, that Dupuytren, Magendie, and Breschet, have purposely kept many dogs for a long time in the most disgusting state of uncleanliness, let them even die in this condition for want of food and water, or even devour each other, yet without exciting rabies (Did. des Sciences Mid. T. 47, p. 53 ) Yet Professor Rossi, of Turin, is said to have produced this, or seme similar disease in cats, by keeping them shut up in a room. (Mem. de I'Acad. Imp. de Turin , 1805, A 1808, p. 93, de la JYolice des Travaux.) On the whole, I consider it well proved, that neither long thirst, hun- ger, eating putrid flesh, nor filth, will occa- sion the disease in the canine race. At Aleppo, where these animals perish in great numbers from want of food and water, and the heat of the climate, the distemper is said to be unknown. Nor is rabies found to attack dogs and cats, with particular fre- quency during the copulating season, and therefore, the oestrus veneris cannot be ad- mitted to have any share in its production, as some writers have been disposed to be- lieve. (See Did. des Sciences Mid. T. 47, V- 55.) Although most writers believe in the reali- ty of a poison, or specific infectious princi- ple, in cases of rabies, the fact has been questioned, or absolutely rejected by others. Bosquillon considered the disease always as the effect of fear, or an impression upon the imagination. This view of the matter is far from being new, and has been ably refuted by many authors, and especially by M. De sault, of Bordeaux, who remarks, that horses, asses, and mules, quibus non est in- tellects, had died rabid the very year in which he wrote ; and, it is observed by Dr. J. Vaughan, that an infant in the cradle is som times attacked, while many timorous children escape. Another notion has partially prevailed, that rabies does not depend upon any virus, but upon the continuance of an irritation in the bitten parts, affecting the whole ner- vous system. (Percival; J. Mease ; Girard; ^c.) But, this doctrine confounds rabies and tetanus together, and can only apply to the symptomatic non-infectious hydro- phobia from an ordinary wound, or lacera- tion. The facts, in proof of the reality of a pe- culiar infectious principle in cases of rabies, are too numerous to leave any doubt upon th- subject. Twenty -three individuals were bit or, e morning by a female wolf, of whom thirteen died in the course of a few months, besides several cows, which had been inju- red by the same animal. How could all these unfortunate persons have had similar symptoms, and especially a horror of fluids, had they not been all under the influence of some cause, besides the bites ? The pa- tients who died, were bit on the naked skin ; while in the others, who escaped in- fection, the bites happened through their clothes, which no doubt intercepted the sa- liva, the vehicle of the virus. In the Essay by Le Roux, mention is made of three per- sons, bit by a rabid wolf near Autun, in July, 1781, and, notw ithstanding mercurial fric- tions, they all died of hydrophobia. Of ten other individuals bit by a wolf, nine died rabid. (Rey, Mim. de la Soc. Royale de Mid. p 147.) Twenty-four persons were injured in the same manner near Rochelle, and eighteen of them perished. ( Andry , Ri- cherches sur la Rage, Ed. 3, p. 196.) On the 27th January, 1780, fifteen individuals were bit by a mad dog, and attended at Senlis by the commissioners of the French Royal So- ciety of Physic ; ten had received the bites on the naked flesh, and five through their clothes. Of the first ten, only five lost their lives, three of them dying of decided rabies between the 27th of February, and the 3d of April ; and the other two between the 29th of February, and the 18th of March. Unless the opinion be adopted, that the dis- ease is caused by an infectious principle, a sort of inoculation, it would be impossible rationally to explain the cause of so many deaths from the bites of rabid animals. If the idea, that rabies originates from fear or nervous irritation were true, how could we account for there being such a differ- ence between the usual consequences of the bite of a healthy dog, and those of the bite of one affected with rabies ? Healthy dogs are incessantly quarrelling, and biting each other in the streets, yet their wounds are not followed by rabies ; and as a mo- dern author remarks, if hydrophobia were referrible to nervous irritation derived from the wounded part, how does it happen, that among the thousands of wounded after a great battle, hydrophobia is not seen in- stead of tetanus. (Did. des Sciences Mid. T. 47, p. 61.) But, if it were yet possible to entertain a doubt of an infectious princi- ple in hydrophobia, this possibility would be removed by the reflection, that the disease may be communicated to healthy animals by inoculating them with the saliva of cer- tain other rabid animals. In fact, as I have stated, the bites of such animals are in every point of view only an inoculation ; and the same remark may be extended to the nu- merous instances on record, in which the disease arose in the human subject, as a consequence of a rabiJ dog, or cat, (not suspected to be in this state at the time) ha- ving been played with, fondled, or suffered to lick the naked skin, in which there was at the moment some slight scratch, entirely overlooked. Many of the ancient writers not only be- ‘ lieved in the hydrophobic virus, or infec- tious principle, but even in its diffusion HYDROPHOBIA 87 through the blood, flesh, and secretions in general ; and this hypothesis was professed by Boerhaave, Van Swiet n, Sauvages, F. Hoffman, &c. but, in proportion as the hu- moral pathology lost ground, the foregoing idea was abandoned, and the opinion adopt- ed, that the infection is confined to the sa- liva, and wounded part, in which it has been inserted. The tales of some old authors would lead one to think, that hydrophobia may be communicated by eating the flesh of a rabid animal. ( Fernelius , De Obs. Rer. Caus. et Morb. Epidem. lib. 2, cap. 14; Schenckius ; Mangetus , fyc.) But, respecting these ac- counts, it is remarked, that they are not en- titled to much confidence ; for, it is certain, that rabies never begins as is stated, with regard to some of the cases in question, a few hours after the application of its cause, and its early stage is never characterized by any fury, or disposition to bite. And, be- sides, how can such relations be reconciled with the practice of the ancients, who, ac- cording to Pliny, employed the liver of the mad dog or wolf, as a remedy ? Palmarius also fed his patients for three days with the dried blood of the rahid animal. (Mim. de la Soc.de Mid. p. 136, et le No. 178.) The fie^h of a bullock, which had been bit by a mad dog, and afterward died rabid, was sold to the inhabitants of Medola near Man- tua, yet none of them were attacked with hydrophobia. ( Andry , Richerches sur la Rage, fyc. p. 30.) Dr. Le Camus informed Lorry, that he had eaten the flesh of animals which died rabid, but he suffered no incon- venience from the experiment. And, it is stated in the letter of Dr. L. Valentin, that the negroes in the United States of Ameri- ca had no illness from eating the flesh of pigs, which had died of rabies. ( Journ Gen. de Mid. T. 3, p. 417.) As for the ques- tion, whether the blood is infected ? It is generally considered to be settled in the negative, notwithstanding the account given by I^mery of a dog, which was attacked with rabies, as is said, from lapping the blood of a hydrophobic patient, who had been bled. (Hist, de ’Head. Royale des Sciences , 1707, p. 25.) Dupuytren, Breschet, and Magendie, w r ere never able to commu- nicate rabies by rubbing wounds with blood taken from mad dogs ; and they even seve- ral times injected such blood into the veins of other healthy dogs, yet none of these latter animals were attacked with rabies, though they w^ere kept for a sufficient length of time to leave no doubt upon the subject. (See Did. des Sciences Med. T 47, p. 63.) A point of greater practical interest than the former, is, whether the drinking of the milk of an animal, labouring under rabies, is attended with any risk of communicating the disease P It is asserted by Timaeus, that a peasant, his wife, children, and several other persons, were seized with hydropho- bia, in consequence of drinking the milk of a rabid cow ; and that the husband and el- dest child were saved by medical treat- ment : but, that the wife and four of the children died. It is further stated, that three or four months afterward, the maid and a neighbour, who had partaken of the milk of the same cow, also died of hy- drophobia. (Cons. 7, Obs. 33.) In opposi- tion to this account, however, several facts, reported by othm writers of greater credit, tend to prove, that hydrophobia cannot be communicated by the milk of a rabid ani- mal. ( Nova Ada Nat. Cur. Vol 1, Obs. 55 ; Baudot, in Mem. de la Soc. Royale de Med. an 1782 et 83, T. 2 ,p. 91 . ) The cases reported by F. Hoffman and Cbahert, with the view of proving the pos- sibility of infection, through the medium of the sernen, are of no weight, because, on a critical examination of them, it will be found, that the infection of the women is stated to have taken place very soon after their husbands had been bit, which is quite at variance with the established character of the disease, as it never commences, and of course cannot be propagated in any man- ner, soon after the receipt of the bite. Be- sides, these histories are refuted by others of greater accuracy. (See Baudot in Mem. dr, la Soc. Royale de Med. an 1782, fyc., p. 92; Ricallier, Vol. cit.p. 136 \ p. 211 ; Bouteille, p. 237 ; Boissiere, in Journ. Gin. de Mid. T. IT, p. 296.) Neither can hydrophobia be imparted by the breath, notwithstanding the statements of Caelius, Aurelianus, and some other old writers. A nurse, mentioned by Dr. J. Vaughan, repeatedly kissed a hydrophobic infant, which she had suckled, a,c^l exposed herself incessantly to its breath, but with- out the least ill effects. The fear which has also been entertained of the disorder being receivable from the application of the pa- tient’s perspiration to the skin, is not found- ed upon any authentic facts. Does the infectious principle of rabies re- side in the salivary secretion, or in the mu- cus of the trachea and bronchiae ? The common belief is, that in hydrophobia, the salivary glands are considerably affected. But, it has been remarked by a modern wri- ter, that if these glands exhibit no morbid alteration during the whole course of the disorder; if they are found healthy after death ; if the air-passages are the seat of inflammation ; if the saliva does not con- stitute the frothy slaver about the lips ; and if such slaver, wherewith the disease may be communicated by inoculation, is derived from the inflamed windpipe and bronchiae, and consists of mucus converted into a kind of foam by the convulsive manner in w r hich the patient breathes, there is some reason for questioning, whether the saliva, strictly so called, undergoes the alteration generally supposed ? (See Diet, des Sciences Mid. T. 47, p. 66.) However, this writer is not exactly correct, w'hen he describes the frothy secretion about the mouth, as be- ing altogether composed of mucus from the trachea, since a great part of it is unques- tionably true saliva and mucus secreted in the fauces and mouth. In the stomachs of dogs, which died rabid, Dr. Gillman con S8 HYDROPHOBIA slantly observed traces of inflammation, and he once tried to communicate the disease to two rabbits, by inoculating them with matter taken from pustules, found in the stomach of a rabid do^ • but no infection took place. {On the Bile of a Rabid Animal, p. 32.) According to Professor Rossi, of Turin, the nerves, “ before they grew cold, participated with the saliva in the property of communi- cating rabies ” He asserts, that he once im- parted the disease by inserting in n wound a toil of the sciatic nerve, immediately after it had been taken from a living rabid cat. (See M6m. de I'Acad Imp. de Turin , Sciences , Phys. el Mathem. de 1805 a 1808, part. 93. de la Notice des Travaux.) After all which has been stated, concerning the hypothesis of the infectious principle of hydrophobia being more or less diffused through the solids and fluids of a rabid ani- mal, and not being restricted to the saliva, perhaps, the safest conclusion to be made is, not to reject the opinion altogether, but to consider it as at present requiring further proof. And from observations of what hap- pens in the human subject, the same infer- ences should not always be drawn, as from experiments on animals, which are liable to be attacked with spontaneous rabies of \ de- cidedly infectious character. (S ec Diet. des Sciences Mid. T 47, p. 67.) Although many casts are to be met with in the records of medicine and surgery, tending to convey an idea, that the mere ap- plication of the saliva of a rabid animal to the sound entire skin of tiie human subject, may give rise to hydrophobia, t he assertion is contrary to general experience, and liable to a reflection which must overturn the hypo- thesis ; viz. the slightest prick scratch, abra- sion, or broken pimple on 1 he surface of the body, such as would not be likely in many instances to excite notice, may render the application of the saliva to the part a posi- tive inoculation. Instances are also reported, the tenor of which is to prove, that the hydrophobic virus may take effect through a sound mucous membrane. ( Palmarius , de Morbis Ccnlag. ; Portal , Obs. sur la Rage,p. 131 , Mallhieuin Mem. de la Soc. Royale de M6d. p 310, fyc.) But that this does not happen ir, the human subject is tolerably well proved by the con- sideration, that formerly a class of men made it their business to suck the wounds, caused by the bites of rabid animais; yet none of them contracted hydrophobia from this bold employment. {Bosqnillon, Mem. d6 la Soc d' Emulation , T.5, //. 1.) The example of die nurse, who repeatedly kissed a child without the least. ill effect, while it was dying of ra- bies, as recorded by Dr. J. Vaughan, has been already noticed. However, if hydro- phobia were apparently to arise in any rare instance from the application of the slaver of a rabid animal to the inside of the lips, no positive inference could be drawn from the fact, unless the means were also possessed of ascertaining, that there were no slight abra- sion about the gums, or within the mouth, previously to such application. For the hydrophobic virus to take effect, therefore, it is generally, if not always ne- cessary, that the infectious saliva be either applied to an abraded, wounded, or ulcera- ted surface. In the case of a bite, the teeth are (he envenomed weapons, which a* once cause the solution of continuity, and deposit the infection in the part. But the mere abra- sion of the cuticle, and the application of the infectious saliva to the denuded cutis, will of- ten suffice for the future production of the disease. As the mode of communication, therefore, is a true inoculation, it follows, that the danger must depend very much upon the quantity of infectious matter con- veyed into, or applied to the part, the effec- tual manner, in which the saliva is lodged in the flesh, the extent and number of the wounds, and particularly the circumstance of the teeth of the rabid animal having passed through no clothes, by which the saliva might possibly be effectually prevented from entering the wound at all. Hence, bites on the hands and face are well known to be of the most dangerous description, especially those on the face, the hands being sometimes protected with gloves. From what has been observed, however, it is not to be concluded, that the disease al- ways follows, even when the animal, which inflicts the bite, is decidedly rabid, and some of its saliva is actually applied to the wound- ed or abraded parts. On the contrary, ex- perience fuHv proves, that out of the great number of individuals often bit by the same mad dog, and to whom no effectual prophy- lactic measure is extended, only a greater or lesser number are afterward attacked with hydrophobia. When this difference in the fate of the individual cannot be explained by the intervention of their clothes, the thick- ness of the cuticle at the injured part, the small size and superficial nature of the bite, the ablution of the part, or some other mode in which any actual inoculation may have been rendered ineffectual, it can only be re- ferred to some unknown peculiarities, or dif- ferences in the constitutions of the several individuals. The latter conjecture seems more probable, when the fact is recollected, that some animals are more susceptible of rabies than others, and some appear to resist the infection altogether. Dogs are more susceptible of the infection than the human species. Four men and twelve dogs were bit by the same mad dog, and every one of the dogs died of the dis- ease, w hile all the four men escaped, though they used no other in' an* of prevention but such as we see every d:w fail. There is also an instance of twenty persons being bit by the same mad dog, of whom only one had the disease. Dr. Heysham has defined hydrophobia to be an aversion arid horror at liquids, exciting a painful convulsion of the pharynx, and oc- curring at an indeterminate period after the canine virus has been received into the sys- tem. Dr. Culb n places it in the class ncuro - ses, and order spatyni} and defines it a loath irig and great dread of drinking any liquids- HYDROPHOBIA. 89 from their creating a painful convulsion of the pharynx, occasioned most commonly by the bite of a mad animal. Olliers have sug- gested the following definition, as more com- plete : melancholy, dread of cold air, of any thing shining, and particularly of water ; often arising from the bite of a mad animal. ( Parr's Med. Diet.) However, the latter de- finition is, perhaps, equally objectionable, be- cause there is not invariably a dread of shining bodies. (See Dr- Powel/. s Case , p. S.) While some authors represent it as a nervous disorder, others, among whom is Boerhanve, consider it as one of an inflam matory nature. In many systems of sur- gery, hydrophobia is treated of with poison- ed wounds, of one species of which it is strict ly the effect. With regard to the symptoms of hydro- phobia, they are generally tardy in making their appearance, a considerable, but a very variable space of time usually elapsing be- tween their commencement .nd the receipt of the bite. Out of a table of 131 ca'es, none of the patients became ill before the eleventh day after the bite, and only three before the eighteenth. It is pretended by Fouteau, that one patient was bit by a dog in she morning, and was attacked with hy- drophobia at three o’clock in the afternoon. But as this account was communicated to the author a long time after the ■occurrence, and not by a medical man, it deserves little con- fidence. Another case, adverted (o by Mead, is deprived of all its importance by the same consideration. These examples, as well as another reported by Astrnc, in u hich the patient is said to iiave had hydrophobia in less than three days after being wounded on the temples, can at most be regarded only as specimens of symptomatic hydrophobia. (Diet, des Sciences Med. T. 47, p. 74.) There appears to be no determinate period, at which the disorder makes its attack after the bite ; but it is calculated, that the symptoms most frequently commence between the 30lb and 40th day, and that after (his time the chances of escape increase. Of 15 patients, whose cases Trolliet was acquainted with, seven were attacked between the 14th and 30th days; five between the 30th and 40tii ; two a little beyond the iattel- period ; and one after 14 weeks, in May, 1784, 17 persons were bii by a rabid wolf, near Brive, of whom 10 were afterward attacked with hy- drophobia; viz. one on the 15th day after the bite ; one o i the 18th ; one on the 19th ; one on the 28th ; one on the 30th ; one on the33d ; one on the 35th ; one on the 44th; one on the 52d ; and the last on the6Sthday. (Hist. delaSoc. RoyaledeM6d.p.2 09.) Fothergilland Mo-, iy mention cases, in vv h i < b the disease began four months alter ihe bile; and M Matthey. ot Geneva, details an instance, in which the interval was 117 days. (Journ. Gen. T- 54, p. 275) , Haguenot knew ot a case, in which the interval between the bite and the commencement of the illness was five months. (Portal, p. 183.) Dr. J. Vaugh- an mentions an interval of nine months; Mead, of 11; Galen, Bauhin, and Boissiere, Vol. IF 12 of a year; Noursc, of 19 months; and R. Lentilius, of three years. Dr. Bardsb y, of Manchester, has recorded a case, in which the rno-t careful inquiries tended to prove, that the patient had never suffered the least injury from any animal, ex- cept the bite, inflicted twelve y*-ars previous- ly to the commencement of hydrophobia, by a dog apparent ! v mad. (Mem. of Liter, and Phil Society of Manchester, Pol. 4, Part 2, p. 431.) A merchant of Montpellier is also stated to have been attacked with hydrophobia ten years after the bite of a rabid dog, which also bit the patient’s brother, who died hy- drophobic on the 40th day after the accident. (See Diet, des Sciences Med. T. 47, p. 75.) Here may also be found references to cases, i t which the interval is alleged to have been IS, 20, and even 30 years. It is certainly difficult to attach any credit to these very late periods of attack. Dr. J. Hunter consi- ders 17 months, and Dr. Hamilton 19, the longest interval deserving belief. (On Hydrophobia, Vol. 1 ,p. 113.) Exposure to the heat of the sun, violent emotions of the mind, and tear, are believed to have consi- derable influence in accelerating the com- mencement ot the symptoms. That mental alarm is also of itscif sometimes capable of bringing on a simple hydrophobia, totally unconnected with infection, is incontestable ; a case, which has not always been duly dis- criminated. A most convincing proof of this fact i- recorded by Barbantini, in the Italian Journ. of Physic, Ciiymistry, &c. for January ami February, 1817. A young man was bit by a dog, which he iancied was mad, arid on the 5 tit day he evinced symptoms of hydrophobia, ot which he was nearly dying, when the dog which had bit him, was shown to him perfectly well, atid the intelligence tranquillized him so effectually, that he was quite well four days afterward. Mr. John Hunter is said to have mentioned in his Lec- tures a very similar case, in which he believ- ed the patient would certainly have died, if the dog which inflicted the bite had not been found, and shown to the patient perfectly well. (See Journ. Gen. de Med. T. 4J, p. 215.) It is to the effects of terror, that seve- ral modern writers are disposed to refer the instances of very late attacks of hydropho- bic symptoms after the period when the pa- tients were bitten ; though, unless the intel- lects be changed in the mean time' by other causes, it is difficult to conceive, why Ihe alarm should not have the greatest effect earlier, while the impression of the danger is undiminished by time. The idea, that the symptoms begin sooner after the bite of a wolf, than that of a dog, is not adopted by a writer who has taken great pains to collect information on the present interesting dis- order. (8ee Diet, des Sciences Mid. T. 47, p. 77.) Cullen has divided the disease into two stages, the hydrophobia simplex and rabiosa ; or the melancholy and raving stages of some other writers. But as the early stage is fre- quently unattended with any thing like me- hydrophobia. 00 lancholy, it is best merely to adopt the dis- tinction of the first and second stages ; one comprehending t he effects of the disorder previously to the occurrence of a dread, or decided aversion of liquids; the other, the subsequent changes. The wound, if treated by common methods, usually heals up at first in a favourable manner. At some inde- finite period, and occasionally, long after the bitten part seems quite well, a slight pain begins to be felt in if, or the neighbouring parts, now and then attended with itching, but generally resembling a rheumatic pain. If the bite took place on the linger, the pain successively extends from the hand to the lore arm, arm, and shoulder, without any redness or swelling in these parts, or any increase of suffering from pressure or motion of the limb. In a great number of instances the trapezius muscle, and the neck, on the same side as the bite, are the points to which the pain principally shoots. The cicatrix, in the mean while, begins to swell, inflames, and often festers and discharges an ichorous matter. These uneasy painful sensations re- cur from time to time, and usually precede any dread of water several days ; and they are a just reason for apprehension. Some times pains of a more flying, convulsive kind, are felt in various parts of the body. As the disease advances, the patient complains of the pain shooting, from the situation of the bite, towards the region of the heart. Some- times instead of pain, there is rather a feel- ing of heat, a kind of tingling, or even a sen- sation of cold, extending up to the chest and throat. Occasionally no local symptoms take place : thus Sabatier, in giving account of se- veral cases, remarks it as worthy of notice, that the bitten parts did not become painful previously to the accession of the fatal symp- toms ; nor did any swelling, or festering occur. (See Mdm. de I'lnstilut. National , T. 2, p. 249. <^c.) Dr. Marcet particularly observed, that the pain follows tiie course of the nerves, rather than that of the absorbents. In the case which he has related, as well as in one of the cases detailed by Dr. Babington, there was pain in the arm and shoulder, but without any affection of the axillary glands ; and in ano- ther case, (See Medical Communications, Vol. 2,) the pain, occasioned by a bite in the leg, was referred to the hip and loins, without any affection of the inguinal absorbents. ( Medico-Chir . Trans. Vol. 1 p. 156.) Of the accuracy of the foregoing statement, by Dr. Marcet, there is no doubt : the observation, however, in regard to the irritation not affect- ing the absorbents, was long ago anticipated by several authors, who urged the freedom of the lymphatic glands from disease, as an argument that the disorder did not depend upon the absorption of any virus. It is also noticed by others, who inclined to the belief, in the absorption of the infectious principle. “ Resorptiouem virus ope syslematis lympha- tic! fieri verisimiliirnum videtur ; neque ta- rnen nee vasa lymphatics, necglandulae vici- nae stimulo morboso, vel tumore adfici videntur ; quod in aliis resorptionibus virulen- tis fieri sole?. ; ( CaUisen Sijsl. Ch/irurgite Hodiernal, Vol. 1 ,p. 595, Hafnice, 1798.) Pain and heaviness are felt in the head. Sometimes, the headach is at first very se- vere : sometimes but slight ; but, in the latter case, it often becomes intense, general, and accompanied with a sense of pressure upon the temples. In certain instances, the pa- tient’s sleep lasts a good while, though dis- turbed by dreams; while, in other more frequent examples, he is continually restless. The intellectual functions generally seem in- creased; the memory stronger; the concep- tion more ready ; the imagination more fer- tile ; and the conversation more animated. However, some patients are silent and de- jected, and, when questions are put to them, the answers are short and peevish. But the greater number are active, lively, and talka- tive. At the same time, the organs of sense betray signs of increased sensibility ; and the eyes, which are very open and bright, avoid a strong light. Sometimes, the pupil is found to be considerably dilated. Extraor- dinary pains are felt about the neck, trunk, and limbs. It is not uncommon also for the patient to evince great anxiety, or to fall into a state of dull despair and melancholy. These last symptoms, of which great notice is taken by writers, are particularly ascriba- ble to the effect of fear. The disorder of the organs of digestion is sometimes manifested in various ways, though it is far from being so frequent and striking, as the affections of the head, which precede it. The disorder refer- red to, consists at first in loss of appetite; nausea; vomiting; and afterward constipa- tion, and sometimes colic. In the first stage of the disease, the pulse is generally some- what more frequent and strong than in health, and the countenance appears more animated. The above symptoms precede the second stage, or that of decided rabies, only by a few days, usually four or six, though some- times but two or three. (Diet, des Sciences Med. T. 47, p. 78.) The second stage of hydrophobia com- meuces with the first manifestation of the dread, or aversion of liquids. The ungovern- able agitation and distressing sense of suffo- cation excited by the sight of liquids, the at- tempt to drink, or even the mere idea of drinking, is unquestionably the most remark- able symptom of the disorder. The patient is also frequently attacked with the same kind of commotion and suffering, from other causes, such as the least agitation of the air, or exposure to a strong light. Indeed, some patients are so much affected by a blast of wind, that they have been known to endea- vour to elude it by walking with I heir backs towards it ; (Hist, de la Soc. Roy. de Med. p. 157,) while others scream out whenever the window or door of their room is opened. (Morgagni De Sed. et Cans. Morb. Epist. 8, No. 28,) Dr. Marcet, in relating the case of the pa- tient affected with hydrophobia, observes, that “on our proposing to him to drink, he started up, and recovered his breath by n deep convulsive inspiration ; yet, he express- HYDROPHOBIA. 91 cd much regret, that he could not drink, as he conceived it would give him great relief, his mouth being extremely parched and clarn- mv On being urged to try, however, lie took up a cup of water in one hand, and a tea-spoon in the other. The thought of drink- ing out of the cup appeared to him intolera- ble ; but, he seemed determined to drink with the spoon. With an expression of ter- ror, yet with great resolution, he filled the spoon. and proceeded to carry it to li is lips ; but before it reached his mouth, his courage forsook him, and he was forced to desist. He repeatedly renewed the attempt ; but, with no more success. His arm became rigid and immoveable, whenever he tried to raise it towards his mouth, and he struggled in vain against this spasmodic resistance. At last, shutting his eyes, and, with a kind of convulsive effort, he suddenly threw into bis month a few drops of the fluid, which he actually swallowed. But, at the same in- stant, he jumped up from his chair, and flaw to the end of the room panting for breath, and in a state of indescribable terror.” (See Med. Chir. Trans. Vol. l,p, loS.) Even the splashing or running of any liquid causes a great deal of inconvenience. As the system becomes more and more affected, the patient loses his sleep entirely, and has frequent and violent fits of anxiety and loud screaming from slight causes. The woman, whom Dr. Powell attended, was often attacked in this way, in consequence of so trivial a circum- stance as a fly settling on her face. The noise of tea cups, or the mention of any sort of drink, greatly disturbed het* 1 , though sbe was not at all agitated by the sound of her urine. The currents of air entering her room, when- ever the door opened, became very distress- ing to tier, and ibis more and more so. The pain in her neck became so great, that she could scarcely bear it to be touched ; but she made use of a looking-glass without (he in- convenience, which hydrophobic patients usually suffer from the sight of shining bo- dies. Dr. Powell states, that the paroxysms, which this poor woman suffered, resembled those of hysteria, and increased in duration as the disorder lasted. “ She described their commencement to be in the stomach, with a working and fulness there, and that a prick- ing substance passed up into her throat and choked her; she screamed suddenly, and grasped firmly hold of her attendants, as if voluntarily ; and muscular convulsions came on, which were 1 sometimes more, sometimes less general and violent. The causes from which these paroxysms arose were extremely slight ; the passage of a fly near her face, the attempt to swallow a pill, a stream of air, the sight of oil or wine, or any other liquids, even the sound of water, and other such circumstances, were sufficient; she now also complained of inconvenience from light, which was accordingly modera- ted. The effect of sounds was peculiar; for though in the subsequent stages their influ- ence became more general, at this period the effect was rather proportionate to the ideas they excited in her mind, than to their vio- lence. Bells, and other strong noises, did not agitate her, hut the clatter of earthen- ware, (he noise of a distant pump, or any thing connected with liquids, produced the paroxysms in all their violence.” She could swallow fresh currants with less resistance than any thing else, taking care that they were perfectly dry. Her mind had, fill now, been quite cairn and composed, and her con- versation and behaviour proper, during the intervals of the convulsive attacks. But Dr. Powell was obliged to discontinue the pills of argentum nitratum, in consequence of the sufferings which the attempt to swallow them regularly brought ou. Fifteen grains of this substance had been given without any sensible effect-. The fits, and the irritability to external objects, increased. The pain shot from the back of the neck, round the angles of the jaws, the chin, and throat. At length the paroxysms became more frequent, and, indeed, might be said to come on spontane- ously : seven occurred in one hour. She looked pale and exhausted, anil a tremor and blueness of her lips and fingers were obser- vable ; her pulse became weaker and more rapid, and her scalp so tender, that touching it brought on convulsions. She had, latterly, eructations of wind, and spit up some thick viscid saliva. Her urine now came away in- voluntarily, and siie was ysore and more irri- table and uncontrollable* indeed, she passed two hours in almost constant convulsions ; became extremely irritable and impatient of every thing about her, complained of failure of her sight ; wished to be bled to death ; her words were fewer and interrupted ; she struck, and threatened to bite, her attend- ants ; had copious eructations of air; dis- charged an increased quantity of viscid saliva with much convulsive effort ; said the affec- tion of her throat and stomach had quite left her; and continued in a general perspiration, with a weak pulse from 140 to 150. She af- terward bit some of the attendants, and was therefore confined with a waistcoat. From (his period, she had lost all control over her mind, and continued for almost four hours in a paroxysm of furious insanity. She now swallowed, with an effort, near half a pint of water : but this was, in a few seconds, vomit- ed up with some mucus, and a greenish fluid. In this violent raving state, she continued till within two hours of her death, which took place forty-seven hours after the first marked occurrence of hydrophobia. In the course of the case { she swallowed, once or twice, a little porter ; and also some cinnamon-water, with tinct. opii : but they were always vomit- ed up. (Dr. Powell's Case of Hydrophobia.) It is by no means uncommon tor a period to occur, when the horror of liquids undergut s a considerable diminution, or even entirely ceases; the patient quenching his thirst, and this sometimes as well as if he were in peifect health, and so as to raise doubts of the exist- ence of rabies. But after a few hours, the dread of fluidscomes on again, and with it the convulsive paroxysms, which now become ge- neral. violent, and incessant. Dr. Cayol at- tended a girl, labouring under rabies, who HYDROPHOBIA. 92 was never affected with any very great dread of liquids, nor an absolute inability to swal- low them, though she certainly disliked them, and swallowed >hem with difficulty. ( Journ . de Med. Chir. tyc. Avril., 1811, p. 241.) IN ay, patientsare sometimes seen, ho can man .ge to swallow red wirie and broth, though their aversion to water is alread) beyond all con- trol; and other patients can sometimes look tit a liquid in a black put without inconvenience ; though any fluid ottered to them in a glass will bring on a violent paroxysm of spasm and sense of suffocation. The sight of tears has even been enough to bring on the attack. (See Diet. des Sciences Med. T. 47, p. 79.) The question lias sometimes been enter- tained, whether rabies can ever exis-t quite unattended throughout its course with a dread of liquids ? The possibility of such a case was believed by Mead and others, and an in- stance is recorded by Migriot, in which the patient died, without having manifested any sign of hydrophobia. (See Hist de la Soc. Roy. de Med. an 1783, 2 me Part. p. 48.) How- ever, it is asserted, that a careful perusal of this case must produce a conviction, th.it the disorder was not raoies ; and it is added, that when the histories of this disease on record are critically investigated, none will be found complete, which do not make mention of a more or less decided aversion to fluids. It also appears from the facts referred to, that the dread of liquids does not depend upon the pain, which the patient has already suffered from his attempts to drink, as it sometimes occurs before any such attempt has been actually made. ( Vol . cit.p. 80) An inclination to bite has been noticed, as happening in the patient, whose case is recorded by Dr. Powell. Yet, this disposi- tion is far from being usual ; and it never presented itself in any of the cases which fell under the observation of the author of the article rage in the foregoing publication, or P. Desault, Duchoisel, Dr. J Vaiighan, Sabatier, Dupuytren. &c. And even when the patient’s imaginalion is so disordered, that he cannot help biting, he commonly warns the bystanders to avoid the danger. The frolhy slaver, which is voided with considerable and repeated efforts, is a symp- tom, which is said not to commence before the respiration begins to be convulsive. As the disease advances, there is no remission of the sputaiion, necessary to clear the throat of this viscous secretion ; and at the approach of death, when it cannot be ex- pelled, it collects in the mouth, and covers the patient’s lips. The symptoms of what is termed cerebral excitement become stronger and more marked in the second stage of the disease. The eyes, the brightness of which is still further increased, appear, as it were, infla- med-; the patient never shuts them again ; and as the daylight and brilliant colours are offensive, he prefers darkness. The hearing becomes very acute, and as well as the sight, is troubled with hallucinations. The touch is extremely fine ; the speech abrupt and rapid ; and the conversation energetic, and often expressive of the most touching sentiments, {Did. des Sciences Med. T. 47, V • 1 •) Dr. Marshall made a very just distinction between the real convulsions which came on towards the termination of the case in death, and the strong sudden action of the muscles, excited in the course of the disor- der by the light, the sight of liquids, and the feel of the air. {The Morbid Anatomy of the Brain, fyc. p. 88.) Convulsions and hic- cough, in fact, are the symptoms of disso- lution. Delirium is far from being a constant symptom, and only happens the last day of the disorder. ^Neither is it always without remissions ; for the patients affected with it sometimes give rational replies. Kvery case upon record, where delirium is described as being one of the first symptoms, or as com- ing on with the dread of liquids, is set down on good authority, not as true rabies, but a symptomatic hydrophobia, attended with mania. The dread of swallowing liquids, though the most singular symptom of the disease, constitutes but a small part of it. It is true, that none, or very few recover, who have this symptom, yet they certainly do not die in consequence of the difficulty of swallow- ing liquids ; for the human body could easily exist double the time, at the end of which the disease usually proves fatal, without food or drink. Besides, the sick can often swallow substances that are nourishing, in a pulpy state, without, however, having their life thereby at all prolonged. It is not, there- fore, the difficulty, or impossibility of swal- lowing liquids ; but the effects of the poison upon the constitution at large, which occa- sion dea*h. {Dr. J. Hunter in Trans, for the Improvement of Med. Knowledge , Vol 1, p. 305.) The extreme sensibility of the sick to all impressions, appears in the displeasure which they express at even the air blowing upon them ; in their dislike to a strong light ; in their aversion to new faces, or even tiie sight of their friends and relations ; and in the terror they express at being touched, which almost threatens to throw them into convulsions. As the disease advances, the mind is more and more filled with dreadful fears and apprehensions. {Op. cit.p. 307.) In the second stage, the epigastrium, as well as the chest, is the seat of considerable pain ; the patient is constipated, but the urine is plentiful and high coloured. Before a certain period, the pulse is generally strong, regular, and a little accelerated ; but towards the end of the case, it becomes small, irregular, feeble, and rapid. (See Did. des Sciences M6d. T. 47, p. 83.) The duration of life, from the appearance of hydrophobia till death, varies from thirty- six hours to four or five days : the most common period is fr. • m tvyo to three days. {Dr.J. Hunter, Op. cit.p. 308.) The event is said to be directly caused by asphyxia, or the cessation of respiration. Of ten persons, who were bitten by the same animal, nine HYDROPHOBIA. died on the second and third day, from the commencement of the horror of fluids, and only one on the fifth day. There is an account of a child at Senlis, who lived nine days, but the description of the case, and the cir- cumstance of fourteen worms being found in the intestines, may raise doubts about the nature of the disease. (See Hist, de la Soc. Hoi/, de Med. p. 209, 155.J Whatever may be the resemblance found between rabies and hydrophobia, with re- gard to the rapidity of their course, their causes, and some of /their symptoms, the following considerations, as a modern wri- ter observes, will always serve for the dis- crimination of one disorder from the other: tetanus attacks the muscles of the jaw, w hich remains motionless, w hile in rabies, the jaw is not only moveable, but incessantly mo- ving, in consequence of the efforts unremit- tingly made by the patient to free bis mouth from the thick saliva with which it is ob- structed. In this last disorder, the muscles are alternately contracted and relaxed ; but in tetanus, they always continue rigid. Te- tanus is rarely attended with any aversion to liquids, and the patient may be kept for a long time in a bath without inconvenience ; and the paroxysms are neither excited, nor increased by a vivid light, a noise, the pa- tient’s being touched, or the sight of water, or shining surfaces. In addition to these differences, it is to be remembered, that tetanus is most frequent in warm climates, and that it mostly comes on a few days after the receipt of a local injury, and may occur as a complication of any kind of wound, even that which is made in a surgical ope- ration. (See Diet, das Sciences Med. T. 47, p. 86.) On the subject of prognosis, with respect to the bite inflicted by a rabid animal, and its effects, as evinced in the decided form of rabies, there are several things worthy of attention. According to some writers, small wounds are not less dangerous than others, and an attempt is made to account for the fact, by the more copious hemorrhage from larger wounds, and the frequent neglect of lesser injuries. Perhaps another reason is, that the virus is more likely to be confined in a wound with a small orifice, than in one which is ample, and admits of being more effectually washed. The more numerous the wounds are, the greater is the risk. If it be inquired, what is the average number of persons attacked with rabies out of a given number w ho have received bites ? The question can only be answered by r/ - ferring to the extremes. Thus, Dr. J. Vaugh- an speaks of between twenty and thirty individuals, bit by a mad dog, ot whom only one was afterward attacked with rabies ; and Dr. J Hunter teljs us of an instance, in which out of twenty-one persons bit, only one became affected. (See also Folhergill in Med. Obs. and Inq. Vol. 5, p. 195.) On the other hand, out of fifteen persons bit by a mad dog, and taken care of at Senlis, three at least were seized with the disorder, (Hist, de la Soc. Roy. de. Med.p. 130 ;) of seventeen 93 others bit by a wolf, ten were attacked ; (ib. p. 130;) and of twenty-three, bit by a she-wolf, thirteen died of rabies. (L. F. Trolliel, Nouveau Trait 6 de la Rage, fyc. Obs. Chirurgique, fyc. No. 25.) a wo important facts should always be recollected ; viz. the disease may often be prevented ; it can hardly ever be cured. Experience has fully proved that when hy- drophobia once begins, it generally pursues its dreadful course to a fatal termination, the records of medicine furnishing very few unequivocal and well-authenticated cases to the contrary. Hence, the imperious ne- cessity of using every possible means for the prevention of the disorder. Probably, however, many things which possess the character of being preventive of hydrophobia, have no real claim to such reputation. I would extend this observation to all internal medicines, mercurial fric- tions, and plunging the patient for a consi- derable time under water. The instances, in which a prevention is inferred to have taken place, by different w riters, in consequence of such means, may all be very rationally ascribed to other cir- cumstances. Facts already cited sufficiently prove, that out of the great number of per- sons frequently bitten by the same dog, only a limited proportion is commonly affected . The hydrophobic poison is known to reside in the saliva of the animal ; consequently, the chance of being affected must greatly depend upon the quantity of this fluid which is insinuated into the wound ; and if the teeth of the animal should have previously pierced a thick boot, or other clothing, be- fore entering the skin, the danger must be obviously much diminished. Many patients wash and suck the w r ound, immediately after its occurrence, aqd thus, no doubt, very often get rid of the poison. Even wdien it is lodg- ed in the wound, it may not be directly ab- sorbed, but be thrown off with the discharge. All prudent patients submit to excision of the bitten part. Now. under each of the above circumstances, escapes have frequent- ly occurred, while internal medicines, half drowning or salivating the patients, had also not been neglected, so that all the efficacy of preventives has too often been most unjustly ascribed to means, which probably never yet had, and never will have, any beneficial effect whatever. What confirms the truth of the preceding statement is these facts: that persons bitten by the same animal have sometimes been treated exactly on the same plan ; some of them escaped the disease ; others had it, and of course perished : on other occasions, some of the patients, bit- ten by the same animal, have been treated in a particular way, and have escaped hy- drophobia; w hile others bitten at the same time by the animal, also never had any con- stitutional effects, although they took no medicines, nor followed any other particu- lar plan. If to these reflections be added the con- sideration, that it is frequently doubtful, whether the bite has actually been inflicted 94 HYDROPHOBIA. by a truly rabid animal, and that the men- tal alarm will sometimes bring on a symp- tomatic hydrophobia, it is easily conceiva- ble, how mistaken a person may be, who believes that he has prevented the disorder, and how unmerited is the reputation of the means, which ho has employed for the pur- pose. The bite of a naturally ferocious beast has often been thought to be attended with more risk than that of an animal naturally f ame ; and hence the bite of a wolf is said to be more frequently followed by rabies, than that of a dog. This proposition is ad- mitted to be true ; but the explanation is erroneous. The true reason of the differ- ence is, that a wolf usually seizes the face, and inflicts a deeper bite; while a dog only snaps as he runs along, and mostly bites through the clothes. (See Dirt, des Sciences, Med. T. 47, p. 88.) The bite of a rabid ani- mal may be rendered much more dangerous by being situated near a part, or an organ, which increases the difficulty, or risk, of adopting an effectual mode of removing the whole of the flesh, in which the virus may be lodged. Thus, bites near the large arteries, the eyes, the joints, &c. are of a more serious description than others. Dr. J. Hunter rated the hazard in some degree by the vascularity of the bitten parts. The prognosis will always he more unfavourable, when no proper measures have been applied to the bite soon after its infliction, and per- haps the risk may be increased by certain causes not having been duly avoided, which, as already stated, are thought to have a ten- dency to accelerate the attack of rabies. The exact time after a bite, when the prevention of rabies is no longer practicable, is quite an undetermined point ; but every fact known upon the subject, evinces in an urgent man- ner the necessity of adopt big preservative measures without the lea^t delay. In almost all the dissections of patients, who have died of rabies, certain indications of inflammation have been perceptible *, mure frequently, in some part of the space between the pharynx and the. cardiac orifice of the stomach, in the stomach itself, in the lungs, the choroid plexus, and membranes of the brain. (See Med. Repository. Vol. 3. p. 51.) 3V1. Troliiet opened with the greatest c ue sis bodies of persons destroyed by this disease. The mouth and fauces in each subject were first examined, and found of a pale grayish colour scarcely lubricated with mucus, and quite free from all frothy matter. All the salivary glands seemed perfectly healthy. When the larynx, trachea, and bronchia; were opened, they appeared to have been the seat of inflammation, the traces of which were the most marked low down, where the mucous membrane was of the colour of wine-lees. In four of the bodies, frothy mu- cus was perceived in the bronchia;, larynx, and trachea. Troliiet infers from these ap- pearances, that the frothy matter seen about the mouths and lips of patients affected with rabies, is secreted by the inflamed mucous membrane of the bronchia;, arid tlmt it is this secretion, and riot the veal saliva, which- contains the hydrophobic poison. (Nouveau Trails de la Rage, 4 c ) In giving an ac- count of a dissection, Faure also long ago remarked, that the frothy matter was only met with in the air-passages, that the sali- vary organs were unaffected, and that the saliva itself did not contribute to the form- ation of the thick slaver, which appeared to have issued from the chest. (Hist, de la Soc. Roy. de M6d. ann. 17S3, p. 39.) From the preceding observations, and those of Mignot de Genety (Vol. cit.p. 54,) Morgagni (De Sedib. et Caus. Morb. Epist. 8, art. 20, 25, 30.) Darlue (Journ. de Med. de Vander- monde. T. 4, p. 270 ;) B. Rush; and Dupsey (Obs. InMites, No. 138) it would appear: 1 That the mouth, strictly so called, and the salivary glands, are without any al- teration. 2. The mucous membrane of the air-pas- sages is affected with inflammation, which in its highest degree extends from the divi- sion of the bronchia; to the pharynx. .When the inflammation is of less extent, the pha- rynx appears sound ; and when yet more limited, it is usually not to be traced in the larynx. The point where it seems to com- mence and is most strongly marked, is at the lower part of the trachea, or in the bron- chia;. Lastly, when none of these parts are found inflamed, the lungs themselves present vestiges of inflammation. With respect to the theory of Troliiet, wherein the hydrophobic poison is said to be contained in the mucous secretion void- ed from the lungs, and to be the product of inflammation of the membrane of the bronchia;, and not derived from the sali- vary glands; the question requires the- confirmation of experiment ; for, though the salivary glands are not the seat of pain, swelling, fcc. it, by no means follows, that their secreting process may not have been subject to some peculiar modification, on which the production of the hydrophobic virus depended. Thus, severe and obstinate ptyalisras often occur, and yet there is no manifest change in the state of the salivary glands. According to Van Swieten and Mead, there are also sometimes no morbid appearances either in the head, fauces, chest, or stomach. (Comment, in Bocrh. T. 3 ,p. 562.) In three cases, out of six, the lungs were found emphysematous, that is to say, their interlobular substance was distended with air, and the pleura pulmofialis raised into a great number of transparent vesicles on the surface of the lungs. In a fourth instance, the emphysema was not observed in the lungs themselves, but in the cellular substance between the two layers of the mediastinum ; and under the muscles of the neck. Mor- gagni also noticed vesicles of air on the sur- face of the lungs of a person, that die^ of hydrophobia.' (DeSed.cl Cans. Morb. Epist. 8, art. 30.) M. Troliiet presumes, that this emphysema is occasioned by the rupture oi one of the air-cells, in the convulsive efforts of respiration, as sometimes happens when HYDROPHOBIA. 95 a foreign body is lodged in the larynx. (See Cases by Louis and Lescure in Mem, de V Acad, de Chir. T. 4 ,p. 538 ; T. 5, p. 527 ) The lungs were of a deep-red colour in all the six subjects dissected by Trolliet, and they were observed to be gorged with blood in cases reported by numerous writers: as Bonet (See Van Swieten , T 3, § 1 140 ;) Bo- erhaave (Op. Omn. p. 215 ;) Morgagni (De Sedibus et Cans. Morb. F.p. S, art. 23, <^c. ; ■ Mead, Darlue (Recueil Period, fyc. T. 3. and 4 ;) Faure (Hist, de la Soc. Roy. de Med. p. 39 ;) De la Caze (ib. p. 69 ;) Portal, Old- know, Ballingall (Edinb. Med. and Surg. Journ. :) Marshall (Morbid Anatomy of the Brain, fyc. p. 69 ;) Gorey (Journ. de Med. Chir. T. 13, p. 83 ;) Ferriar (Med. Hist, and t Reflections , §c.) u Pnlmones in quinque * nigri ex toto, aut magn& parte (says Morgag- ni,) in quatuor magna item ex parte sanguine pleni.” With respect to the state of the or- gans of the circulation, in three of the cases dissected by Trolliet, a good deal of air escaped from the heart and aorta. Morgagni is supposed to be the only other writer, who has noticed a similar occurrence (Epid. 8, Mo 30,) and who also in another case saw air escape from beneath the dura mater. (Ib. No. 23.) fn two of Trolliet’s cases, some gelatinous clots were found in the heart and large vessels ; but the great mass of blood was black, and very fluid in the heart, arte- ries, and veins, as in subjects, who have died of asphyxia. In all the six cases, traces of inflammation were noticed in the brain, or its membranes. The sinuses w ere filled with a dark-coloured fluid blood ; and the pia mater was much injected, and of a brownish hue. The same appearances were found above the cerebellum, and the vessels on the investment of the medulla spinalis w r ere con- siderably enlarged. The surface of the ce- rebrum w r as also studded with scarlet spots, which appeared to arise from blood effused from the small vessels of the pia mater into its cellular substance. In two subjects, blood was extra vasated tow r ards the base of the brain in larger quantity. The plexus choroides was gorged with blood, and of a brown colour. Besides those and other changes, Trolhet re- marked, in two of the cases, a thickening of the pia mater. The substance of the brain was generally softer than usual ; but the fluid in the lateral ventricles was not in large quan- tity, though, in tw r o cases, it had a bloody tinge. Tiie late Dr. Marshall believed that in rabies, the brain was the part principally affected. (Op. cit. p. 145.) Hufeland conjectured, that, in hydropho- bia, the medulla spinalis is the part originally affected, whence the effects of the disease are propagated to the nerves of the trunk. (Bibl. Med. T. 55, p. 395, fyc.) Dr. R. Reid believed, that an alteration of the spinal marrow was essentially concerned in the disease. (On the Nature, fyc. of Tetanus of Hydrophobia, Svo. Dublin , 1817.) A caae was also published by M. Matthey, of Gene- va, in which a quantity of serum was found within the spinal canal. (Journ. Gen. de Med. T. 54, p. 279 ) See on this subject some observations by Dr. Abercrombie. (Edinb. Med. and Surg. Journ. Vol. 14. p. 66.) According to Trolliet , the traces of inflam- mation in the digestive organs are not so constant as in the lungs and brain. In none of the six cases dissected by him, was there any appearance of inflammation in the pha- rynx, though some parts of the alimentary canal were atfected in this manner. The cases recorded, however, in which the diges- tive organs presented considerable mor- bid appearances, are very numerous. Thus Joseph de Aromatarius, Darlue (Recueil Pe- riod. T. 3 , p. 189, et T. 4 , p. 270.) Sauvages (p. 107,) Professor Rossi, M. Gorci (Journ. de Med. Chir. tye. T 13.) and Dr. Powel (Case of Hydrophobia,,) found inflammation either in the pharynx, or oesophagus, or both these tubes; Dr. Powell’s words are, “ the oesopha- gus was rather redder than natural, and covered with a thin layer of coagulable lymph.” A similar coat of lymph was also found by Oldknow (Edinb. Med. and Surg. Journ Vol,. 5, p. 280,) Ballingall (Op. cit. Vol. 11, p. 76.) Dr. Ferriar (Med. Hist. S^c. Vol. 3 , p. 27.) In dogs. Dr Gillman found the pharynx and oesophagus in a stale of inflam- mation. (On the Bite of a Rabid Animal ,p, 13, 23, 26, 44.) It is conjectured, that in many of these instances, the inflam- mation extended to the oesophagus from the trachea and bronchi*. (Diet, des Sci- ences Med. T. 47, p. 98.) Inflammation of the mucous membrane of the stomach and small intestines, has likewise been very generally noticed, as may be seen by referring to the accounts published by Morgagni, Powell, Oldknow, Ferriar, Ballingall, Marshall, &.c. In d ;gs, the same fact was remarked by Dr. Gillman (P. 13, 31, 44;) sometimes, however, according to this last author, no vestiges of inflammation, nor any other morbid appearances, are dis- coverable in the examination of animals that have died of rabies. (P 83.) Dupuy- tren is stated to have found the mucous membrane of the stomach and bowels in- flamed in several places, and even almost gangrenous (Diet des Sciences Med. T. 47, p. 98.) From recent investigations, made at the veterinary school at Abort, by Professor Dupuy, the following are tiie usual morbid appearances, noticed in the dissection of dogs, horses, cows, and sheep, destroyed by rabies. 1 The lungs and brain universally gorged w'ith blood. 2. Greater or lesser remarks of inflammation in the mucous membrane of the bronchi*, trachea, larynx, throat, oesophagus, stomach, and frequently even in that of the bowels, vagina, ute y, and bladder. 3. The air-passages filled with frothy mucus. 4. - collection of serum in the ventricles of the brain, and sometimes even betweeh the membranes, covering the spinal marrow. 5. An unusual redness of tiie investment of the pneumogastric and trisplanchnic nerves. (See Diet, des Sciences Med. T. 47, p. 99.) Happily, surgery possesses one tolerably HYDROPHOBIA. DO certain means of preventing hydrophobia, when it is practised in time, and in a com- plete manner Every reader will know, that I he excision of the bitten parts is the operation to which I allude. Indeed, as hy- drophobia is often several months before it begins, the wounded parts should, perhaps, always be cut out, e \ eu though they are heal- ed, and some weeks have elapsed since the ac- cident, provided no symptoms of the hydro- phobia have actually commenced. The operation should be done completely; for a timorous surgeon, afraid of cutting deeply enough, or of removing a sufficient quantity of the surrounding flesh- would be a most dangerous one for the patient. All hopes of life depend on the prevention of the disor- der ; for in the present state of medical knowledge, none can rest upon the efficacy of any plan, except the extirpation of the part. For this purpose, caustics have some- times been employed. However, as their action can never be regulated with the same precision as that of the knife, and con- sequently, they may not destroy the flesh to a sufficient depth, excision should always be preferred. The latter method is also the safest for another important reason, viz. tue part, and poison lodged in it, are removed from the body at once; but when the cau- tery or caustic is used, the slough must re- main a certain time undetached. Some surgeons are not content with cutting out the part: but after the operation, till the wound with the liquor ammoniae, or caute- rize its surface, for the sake of greater secu- rity. How late excision may be done with any prospect of utility I am not prepared to say ; but, there are practitioners, who deem excision right, even when heat, irrita- tion, or inflammation is observed in the bit- ten part. (See Med. Repository, Vol. 3, p. 54.) Cases present themselves, in which it is even preferable to amputate the limb, than attempt to extirpate either with the knife, or cautery the whole of tiie bitten parts ; an endeavour, which could not be accom- plished with any degree of certainty. Thus, as Delpech observes, when the hand or foot has been deeply bitten in several places, it is obvious, that it would be impossible to make caustic, (or the cautery) certainly reach every part, which the saliva of the rabid animal may have touched. Besides, the mischief resulting both from the injury, and the other proceedings together, might be such as to afford no prospect of saving the limb, or at least, of preserving it in an useful state. (See Precis Idem, des Mai. Cliir. T. 2, p. 133.) I have known of one or two cases, in which the patients lost their lives, in consequence o. the excision, or de- struction of the bitten parts ,iot having been attempted, on account of the surgeon’s re- luctance to cut tendons, or wound a large artery, as one of those at the wrist. In such cases, however, the fear of rendering a muscle useless, or of wounding an artery, is no justification of leaving the patient ex- posed to a danger, so surely fatal, as that of the hydrophobic virus, if it once affect the constitution. The artery should be exposed for a sufficient length, and secured with two ligatures, when the requisite extirpation of the parts between them may be safely performed. When once the hydrophobic symptoms have commenced, there is little or no hope of -aving the pa'ient, the disease having almost invariably baffled every plan of treatment, which the united talents of nu- merous medical generations have suggested. All the most powerful medicines of every class have been tried again and again ; mercury; opium; musk; camphor; arse- nic; the nitrate of silver; cantharides ; belladonna; ammonia; plunging the pa- tient in the sea ; bleeding ; be. &c. The inefficacy of opium is now generally acknowledged ; in the space of fourteen hours, Dr. J. Vaughan gave one patient fifty -seven grains of opium, and also half an ounce of laudanum in a clyster, but the fa- tal termination of the disease was not pre- vented. Dr. Babington even prescribed the enormous quantity of 180 grains in eleven hours, without the least amendment, or even any narcotic effect. (Med. Records and Researches, p. 121.) On the very first day, that rabies decidedly showed itself in a man, who had been bit by a mad dog, Dupuytren injected into the vena saphena, by means of Anel’s syringe, two grains of the extract of opium dissolved in distilled water, and as a degree of calm appeared to be the result, four grains mure were thrown into the cephalic vein. The patient re- mained perfectly tranquil three hours longer; but the symptoms afterward recurred with increased violence. The next morning, about six or eight grains more were dissol- ved, and thrown into the circulation ; but, all was in vain, as the patient died in three quarters of an hour after the last injection, (see Diet, des Sciences Med. T.41,p. 131.) As for belladonna, its employment for the prevention and cure of hydrophobia is very ancient, its external use for this purpose ha- ving been mentioned by Pliny, and its inter- nal exhibition, w ith the same view, by Theod. Turquetus in a posthumous work published in 1696. (See Pmxeos Medicce Syntagma, ^•c.) In 1763, belladonna was recommended by Schmid as a remedy for hydrophobia, , and in 1779 by J. H. Munch. (See Richter's Chir. Bibl.) At present, this medicine, has entirely lost its character of possessing any power against hydrophobia. 01 late years, the public hope has been raised by {he accounts given of the virtue of hydro-chlorine, or oxymuriatic acid. Wen- delstadt even published the story of an Eng- lishman, who allowed himself to he bit seve- ral times by a mad dog, and then saved him- self by washing the bites with this acid. And, still more recently Professor Brugna- ttjlli, in the Italian Journ of Physic, Chymis- try, be. ( T . 9, p. 3.4,) has published some observations, lending to prove the efficacy of the external and internal employment of the medicine for the prevention of rabies. HYDROPHOBIA. 97 The biles are washed with it, and then co- vered with chappie wet with it. And, when the symptoms commence, if it could not he swallowed in a fluid form, Brugnatelli gives bread pills imbued with it. For a child eight years old, the dose is 3ij four or five times a day, but gradually increased. According to Orfila, hvdro-chlorine was long since re- commended by Cluzel, as an internal remedy for hydrophobia. ( S&cours a dormer auxper- sonnes empois niees, fyc. Svo Paris, 1818, p. 158.) With regard to Brugnatelii’s cases, they are said to be so destitute of precision and certainty, that no inference can be drawn from them. ( Diet, dcs Sciences Med. T. 47, p. 119.) In order to ive hydro-chlorine a fair trial, it was used internally and externally on seven patients in the Hotel-Dieu at Lyons in 1817. The bites were washed and bathed with it, and some of them also cauterized ; and each patient took daily a dram of the acid, made into an agreeable sweetened drink. All these unfortunate individuals afterward died of rabies, though the treat- ment was begun the day after the receipt of the wounds. ( L . F. Trolliel , Nouveau Troil6 de la Rage, tyc.) The excision of the bites 70 lion rs after their infliction, and washing the wound with oxymuriatic acid, did not in Dr. Johnson’s case prevent the disease. (See Edinb. Med. and Snrg. Journ. Vo!. 15, p. 212.) In America, the plant scuteilaria lateriflora has been lately extolled, as a certain specific for hydrophobia. (See A History of the In- troduction and Use of Scutellaria Lateriflora , as a remedy for preventing and curing Hydro- phobia, by Lyman Spalding, M. D. New- York, 1819.) I'he prussic, or hydrocyanic acid has likewise been proposed, on account of its reputed antispasmodic properties; but, some experiments, made with it on dogs by Dupuytren, iVIagendie, and Breschet, furnish co results in favour of its being likely to prove useful in the present disorder. (See Diet, des Sciences Med. T. 47. p. 133.) By Dr. Rossi, of Turin, the trial of galvanism was suggested. (Alibert, Nouveaux Elemens de Therapeutique , T. 2 ,p. 436, Ld. 4 ;) yet, the only fact brought forward, as an en- couragement to persevere with the last means, appears to a modern author, from its symptoms and progress, not to have been a case of rabies. ( Dirt cit T.41,p. 126.) The rapid and powerful effects of t.he bite of a viper on the whole :-yslem, and perhaps the idea, that the operation of this animal’s venom might counteract that of the hydro- phobic virus, led some experimenters to try what would be the result of subjecting pa- tients, affected with rabies, to the bite of that kind of snake. Tiie project, however, was attended with no success Three cases of this description were communicated to the Royal Society of Medicine, (Hist. p. 201 ;) two additional ones were recorded by Dr. Gilibert, physician to the HOtel-Dieu at Lyons, { Advers . Med. Pract. p. 257;) and Viricel, surgeon of the same hospital, repeated the experiment on a child, which yet fell a vic- tim to hydrophobia. Other trials are also said to have been made in France and Ger- Voj,. H 13 * many with no better success. Dr. de Mathiis, in the year 1783, let a viper bite a rabid dog on the throat. '1 he dog's head was attacked with considerable swelling, the hydrophobia ceased, and, according to some accounts, the animal perfectly recovered ; but, accord- ing to other statements, though it drank freely as soon as its head had swelled, it only survived the experiment a few hours. (See Diet, des Sciences Med T. 47, p. 126.) Some facts which occurred a few years ago in the East Indies, tended for a time to raise an expectation, that a copious abstrac- tion of blood might be the means of pre- serving patients actually attacked with this fatal disorder. Mr. Tyrnon, assistant surgeon of the 22d Light Dragoons, tried successfully tiie method of taking away at once an im- mense quantity of blood from the patient, “ I began by bleeding him (,says Mr. Tymon) until scarcely a pulsation could be felt in either arm.” Opium was afterward given, and the patient salivated with mercury. (See Madras Gazette of Nov 23, 1811.) Although in the observations, annexed to this case by Dr. Berry, there are some cir- cumstances. which render it probable, that the case was really hydrophobia ; yet, as the successful termination of it is an event so extraordinary, I much regret, that some de- sirable information is omitted. For instance, we have no account of any pain, or changes, in the bitten part, or limb, at the first coming on of the indisposition. The early constitutional symptoms are not described, and the violent spasms, screaming, fcc. are the first things mentioned. Some particu- lars of the dog would also have been inter- esting. Such information, indeed, becomes still more essential, when we find it stated, that another man, Serjeant Jackson, was also bitten by the same doi:, and had hydrophobia in a mild form, from which lie recovered under the use of mercury, blisters to the head, and cathartic injections, without any recourse to bleeding at all. This last case is even more contrary than the former, to what general experience teaches; because mer- cury, blisters, and injections, have been tried a thousand times unavailing!}' ; while, per- haps, blood-letting, in the manner practised by Mr. Tymon , is a new treatment. Dr. Schoolbred, of Calcutta, published a second case of hydrophobia cured by bleeding ad deliquium aniroi, and afterward exhibiting calomel and opium. The patient, being threatened with a relapse, was largely bled again. The whole of tiie success is imputed by Dr. Schoolbred to the venesection. But this gentleman is not so sanguine as to be- lieve. that, bleeding will cure every case of hydrophobia. It is probable, that there is a period, beyond which its curative effect} cannot extend, and, therefore, it is uponihw, firstappearance of unequivocal.symptomsof the disease, that he thinks copious SBleed mg affords a prospect of success, , -while . t lie delay of only a few hours may proven fatal. He observes, that the medical profession,, taught by numerous disappointments, admit HYDROPHOBIA. 9S very cautiously the claims of any new prac- tice to general adoption. If several patients in hydrophobia, therefore, should happen to be bled in an advanced stage of (he disease, and die, (as they inevitably would do, whe- ther they had been bled or not,) such cases would be quoted against die new practice, as failures But Dr. Schoolbred rightly con- tends, that numerous failures in an advanced sta::e of the disease can form no just ground for the rejection of a remedy, which has in- contestably effected a cure in an earlier stage of the disorder. He insists upon the necessity of making a large orifice in the vein, so as to evacuate the blood quickly, which must be allowed to fiovv, without re- gard to quantity, ad deliquium animi. Dr. Schoolbred was well aware, that bleed- ing in cases of hydrophobia had often been tried. But, says he, owing probably to the evacuation not having been pushed far enough, when used in the early stage of the disease ; or to the period for its beneficial employment having elapsed ; the cases, in which it was tried, afforded little or no en- couragement to the continuance of the prac- tice. Since the preceding cases, the effect of bleeding has had the fairest trials made of it, and some of the reports are in favour of its occasional utility. (See Particulars of the successful Treatment of a case of Hydropho- bia, by R. Wynne , 8 vo. Shrewsbury , 1813; Also Edmonstone in Lond. Med. Repository, Vol. 3, p. 93.) In almost every instance, however, it fails in hindering the usual melancholy event. (See Kirrison's Case and Obs. in Med. Repository, Vol. 2 ,p. 197.) This unpleasant truth, I think, receives confirma- tion from the fact, that the practice is far from being new. Dr. Mead, who was very confident that he had found an infallible preventive of the dis- ease in a little liverwort and alack pepper, aided by bleeding and cold bathing before the commencement of the course of medi- cine, says, ‘as to all other ways of curing the hydrophobia, I own I have not been so happy as to find any success from the many I have tried. Bathing at this time is ineffec tual. I have taken many large quantities of blood; have given opiates, volatile salts, fee. All has been in vain, because too late.” Not- withstanding his disappointment, he con- cludes, “ if any relief could be expected in this desperate state, I think it would be from bleeding, even ad animi deliquium,” tyc. The doctrines of Boerhaave also led him and his pupils to recommend and practise bleeding in hydrophobia. “ The distemper (says he) is to be treated asone highly inflam- matory, upon the first appearance of the signs which denote its invasion, by blood- letting from a large orifice, continued till the patient faints away ; and soon after by euemata of warm water and vinegar, be.. and lie adds. “ that this practice is supported by some small number of trials.” But the particulars of this successful practice, arc not given. Dr. Schoolbred finds, that a trial of it was made at Edinburgh, more than sixty years ago, by Dr. Rutherford who took away gradually sixty ounces of blood from a pa- tient, who had already been bled the same morning. As the patient lived forty-eight hours after the large bleeding, the method was probably tried somewhat early in the disease; and the case may therefore be set down as a fair instance of a failure of the practice. The trials, which have been made in this country of the practice of bleeding, in cases of hydrophobia, since the receipt of the above reports from India, I am sorry to say, have not confirmed its efficacy, as a means which can be much depended upon for saving the patients. Bleeding was also recommended in cases of hydrophobia, by Poupari. (See Hist.de I'Acad. Royale des Sciences, pour I'annee 1699, /?.48.) The practice is likewise men- tioned in the Medical Essays of Edinburgh, Vol. 5, part 2, § 5; and in the writings of Dr. Rush See also Dr. Burton's Case, Phil. Mag. August, 1805. After all that has been said, and the little confidence assigned to any practice but that of the early excision, or amputation of the bitten par's, it is necessary, (hat some- thing should be done after the actual com- mencement of rabies, and that every practi- tioner should be prepared for the adoption of some mode of treatment, or another. As however, my own mind is not made up upon the subject, I prefer offering a conclusion or two, made by a modern critical writer: “ That experience authorizes the placing confidence in bleeding ad deliquium; on vomiting; and perhaps on use of atropa belladonna ; and, on tobacco exhibited as a glyster. That it is probable, advantage would result from the combined employment of bleeding, vomit- ing (see Dr. Sattery's Obs. in Medical Trans. Vol. 4,) and purging in the early stage of the disease. That analogy recommends the trial of spirit of turpentine in the comvulsivo stage of the disease.” ( Med . Repository, Vol. 3 ,p. 54.) Jos. de Aromatarius , De Rabie Con- tagiosa, 4 to. Francof 1626. Sauvages sur la Rage , 12mo. Paris , 1771. James on Canine Madness, 8r o. Lond. 1780. Mead on the Bile of a Mad Dog. Jos. S Dolby, The Virtues of Cinnabar and Musk, against the Bite of a Mad Dog, 41 o. Birmingh 1764. J. Hey sham, De Rabie Lanina, Edinb. 1777. B. F. Munch. De Belladonna, efficace in Rabie Canina re- medio, Frank. Del. op. 1 . D.P. Layard? Essay on the Bite of a Mad Dog, 2 d Ed. 1763. R. Hamilton, Remarks on Hydrophobia, 2 Ed 2 Vols. 8 vo. Lond 1798. Medical Museum, Vol. 2. Lond Med. Trans. Vol. 2 and 4, Ed. 2. Med. Obs. and Inq. Vol 3; and Fothergill in Vol. 5 of the same work. C. Nugent , Essay on Hydrophobia ; to which is prefixed, the Case of a Person cured , 8 vo. Lond. 1753. Le Roux , sur la Rage, 8 vo. Dijon, 1780. Idem. Traite- menl local de la Rage, 8vo. Paris, 1783. Edinb. Med. Comment Vol. 5, p. 42. J Vaughan's Cases and Obs. on Hydrophobia, 8r o. Lond. 1778. Dr. Powell's Case of Hydrophobia. Latta's System of Surgery, Vol. 3. Cullen's First Lines , Vol. 4. Enaux el Chaussier, Me- HYDRO PH THAT.MFA. fhodc dt traltc.r lea Morsure a des Animaux en- rages. , fyc. 12mo. Dijon , 1780. Memoirs oj the Med. Society of London , Vol. 1, p 248. Medical. Communications , Col. 1. J. Mease, An Essay on the Disease produced by the Cite of a Mad Dog, with a Preface , fyc. by J. C. Lettsom, Svo. Philadelphia, 1793. Mem. de la Societe Royale dr Mcdecine de Paris, pour Van 1782 e.t 1788. Ferr tar's Med. Facts and Observations, and his Med. Histories, fyc ‘Id Ed. Svo. Loud. 1810. Callisen's Sy sterna Chi- rurgiir. Hodiernts, T. 1, p. 593, Hafnice, 1798. Marcel, in Med. Chir. Trans. Vol. 1, p. 132, «^-e. Jesse Foote, An Essay on the Rite of a Mad Dog, 8 vo. Lond. 1788. Lassus, Patholo- gic t hir. T. 2, p. 239. fyc Ed. 1809. A valuable Paper by Dr. J. Hunter in Trans, of a Society for the Improvement of Med and Chir. Knowledge, Vol. 1, art. 17. James Gid- tnan's Dissertation on the Bite of a Rabid Ani- mal, Svo. Lond. 1812. Leveille, Aouvelle Doctrine Chir. T. 2, p. 341 , fyc. S. Bardsley in Memoirs of the Literary and Philosophical Society of Manchester, Vol. 4, part 2. Medi- cal Reports, 4'C. ; to which are added the In- quiry into the origin of Canine Madness, and Thoughts on a Plan for its E Germination from the British Isles, 8 vo. Lond. 1807. Ba- bington, in the Medical Records and Researches, Lond. 1798. R. Pearson, Arguments in favour of an Inflammatory Diathesis in Hydrophobia considered, Birmingh. 1798. Art. Hy drop ho bia in Rees's Cyclopcedia. M. Ward. Fads establishing the Efficacy of the Opiate Fraction in Spasmodic and Febrile Diseases ; also an at- tempt to Investigate the Nature, Causes, and Method of Cure of hydrophobia and Tetanus, Svo. Manchester, 1809. Richter's Anfangs. grunde der IVundarzneykunsl ■ B. 1, p. 252, <^c Gott 1799. Cases and Cures of Hydro- phobia, selected from the Gentleman s Maga- zine, 8 vo. Lund 1807. G. Pinckard, Case of Hydrophobia , Svo. Lond. 1808. B. Moseley, on Hydrophobia, its Prevention and Cure, Svo. Lond. 1809. J. F. A. Lalouette , Essaisur la Rage, Svo. Paris, 1812. A Portal, M6mo ires sur la Nature , fyc. des plusieures, Maladies, T. 2, p. 31, 8ro. Paris, 1800. G. C. Reich, De la Ftvre en gdndral, dt la Rage, tyc. 8 vo. Metz. 1800. Bosquilhn M6m. sur les Causes de T Hydrophobie, Svo. Paris, 1808. S. N. Sauter, Esperienze Medicht inlorna la Cura dele Idrophobia, ossia della Malattia proveni- ence dal Morso del Cane Rabbioso, Svo. Bolog- na, 1806. Dr. Berry's Obs. and Mr. Tymon's Case cured, by large blood-letting, as detailed in the Madras Gazette of November 23, 1818 ; and Dr. Schoolbred's Case sucessfully treated by copious bleeding , as related in one of the Asiatic Mirrors for May, 1812. O'Donnel's Cases of Hydrophobia, i S 13. T. Arnold, Case of Hydrophobia successfully treated, Svo. Lond. 1793. R. Wynne, Particulars of the success ful Treatment of a Case of Hydrophobia, Svo. Shrews, 1808. Boyer, fraite des Mai Chir. T \,p. 435, fyc. Paris, 1814 C. IT. Parry, Cases of Tetanus and Rabies Contagiosa, or Canine Hydrophobia. Svo. Lond. 1814 A Marshall, The Morbid Anatomy of the Brain in Mania and Hydrophobia, with the Pathology of these two Diseases, fyc. Svo. Land. 1815. l(. htid on the Nature and Treatment of Te- tanus and Hydrophobic Svo. Dublin , 1817. Aulenrieth , Hiss, de hactenus preetervisa nervo- rum lu dratione in sectionibus hydrophoborum, 4lo. Tub. 1802 Gottfr. Zinke, Neue Ansichten der Hunsdwuth Svo. Jena, 1804. Did. des Sciences Med. T. 22, art. Hydrophobie, et T. 17, art. Raze. G. Lipscombe Cautions and Reflexions on Canine Madness , 8ro. Lond. 1807. C. Gilber , Pract Abhandl. tteber die Vorbeugung , <^-c der Hundswuth, Svo. Wien. 1818 ; This author has confidence in the pow- der of meloe maialis. C. F. Har'es , neber die Behandlung der Hundswuth. 4to. Frank f. 1809 Stramonium recommended. HYDROPH 1 HALAl I A. (fro., water, and the eye.) Dropsy of the Eye. Hydrophthalmus : Hydrophthalrnos. Also Bupthalmos, or Ox-eye. As in other organs, dropsy of the eye arises from a dispropor- tion taking place between the action of the secerning arteries, by which the tluid is de- posited in the part, and the action of the absorbent vessels, by which it is taken up and returned to the circulation ; and, ac- cording to this principle, the disease may- be supposed to depend, either upon secre- tion being made too rapidly, or absorption being slower than is proportionate to the natural activity of the vessels by which the secretion of the humours of the eye is effected. According to Beer, dropsy of the eye is seldom entirely a local disease, but at least is generally combined with an unhealthy constitution, or is a mere symptomatic » effect of some other dropsical affection, anasarca, hydrocephalus, Kc. Sometimes it appears as a symptom of chlorosis. Beer adds, that the disease may originate either from a preternatural accumulation of the aqueous humour ; from that of the vitreous humour ; or from an immoderate accumula- tion of both these humours together. ( Lehre von den Augenkr. B. 2. p. 616, Wien. 117.) When the vitreous humour collects in this manner, it usually loses its natural consist- ence, and becomes thinner and more wa- tery. ( Richter Anfmgsgr. B. 3, p. 392.) Professor Beer states, that in the case proceeding from a morbid quantity of the aqueous humour, the first indication of the disease is an increase in the dimensions of the cornea, attended with a manifest enlarge- ment of the anterior chamber. The cornea may become in this manner two, three, or even four times wider than natural, without bursting or losing its transparency ; for, though a turbid appearance is discernible, this depends rather upon the stale of the aqueous humour itself. The iris, which, in the very commencement of the disease, begins to lose its mobility, soon becomes completely motionless, and acquires a duller colour; the pupil always remaining in the mid-state between contraction and dilata- tion. In the eyeball, an annoying sense of pressure, tension, and heaviness is teit, rather than actual pain. Lithe beginning of the disease, there is a considerable degree of farsightedness, or praesbvopia, which HYDROPHTHALMIA. 1«0 soon changes into a true amaurotic weak- ness of sight, but never terminates in perfect amaurosis The free motions of the eyeball are more and more interrupted, in propor- tion as the organ grows larger, and it has invariably a hard feel, while the sclerotica, to tiie distance of two lines from the mar- gin of the cornea, is as bluish as it is in the newborn infant. Respecting the precise cause of the accu- mulation of the aqueous humour, Beer offers no observation worthy of repetition, excepting perhaps that in which he reminds us, that a similar collection happens appa- rently as an effect of the conical staphylo- ma of the whole cornea (See also War- drop's Essays on the Morbid Anatomy of the Eye, Vol 2, p. 19.) indeed, as far as onr knowledge yet extends, it is impossible to say whether the changes of the cornea are, in the present disease, to be regarded as the cause or the effect of the increased quantity of the aqueous humour, or whether, as seems to me most probable, both phenomena are only effects of one and the same cause. The examples, somewhat repugnant to this idea, are those referred to by Beer, as symp- tomatic of other dropsical affections. On the other hand, Mr. Wardrop has never seen a preternatural collection of requisite to make the eye-hall diminish, and return into the orbit, so a- to be covered by the eyelids. A- f,»r the rest of the Honour lodged in the eve, i; will gradn ally escape of -self. through 'he cncular opening in tli • cornea, w thout any more pressure bei;s.: tn -da. Until tb^ appe trance of th“ inflamm lion, that is, until the third or fif h e after the operation, the dressings re to consist e whole of the anterior part of the eye-ball through the sclrrotica. {Anfangsgr. B. 3, p. 404A It* order 'o lessen the -mlk of the eye, the late VI r. Ford, in one instance, passed a seton through the front of the organ with apparent success. (See Med. Communications , Vol 1.) Consult Maucharl. Dt Parac'entesi Oculi , Tub. 17 44. Conradi, Handbucfi der Pathol. Anat. p. 523. Fieliz, in Huf eland’s Journ. 4 B. p. 208. Flajani , Cullesione d Ossenazioni , T. 1, Obs. 43 Gendron. Mai. d s Yeux. T. 2. Loins, in M6m.de I’Acad. dt Chir. T. 5,4 to. Marchun in Jo m. de Med T. 32, p. 65, Terras, op. cit. Vol. 45. p. 237. Scarpa , Salle principali Mnlattie degli Occhi , Cm . 13 C. P. Begcr , Dr’ Hydrophthnlmia Haller Disp . C/nr. i 575. A. Sanvey , />e Paracentid Ce di in i 7 y dr ophthalmia et Amblyopia Se- nu . - ; H llcr, Disp. hir. 15- 7, Tub. 1744. Benedict, de Mo. bis Hum oris Vitrei. Luke , Diss.de Hydropethalnna, Jen. 1803. Rich- ter. Anfangsgr. B. 3, p. 392, fyc. 67;/. 1795. Beer Lthrev n den iugenkr. B. 2, Wien. 1817. J W.rd op, Essays on the Morbid Anatomy of the II man Eye, Chap. 18 and 40, Vol 2; 8vo. Load. 18i». B. Travers. Synoj is of the Diseases of the Eye, p. 195, p. 1 200, 8ro, Load 1820. HV'DiiOPS. (from ieJa)g, uer.) A drop- sy, o morbid accumulation of w a' or. For hydrops articuli , refer to Joints , diseases of; for hydrops oculi, see the foregoin _ article. With re - i i hydrops pectoris , hydrothorax, or dropsy of Ihe chest , as it is altogether a medi- cal case, an account of its symptoms and tree. - merit w ll hardly be required in this Dictionary. Tue only concern, o itich a sur- geon has ivitlj the disease, is being oceasion- al'y required to make an opening for the discharge of the water. (See Paracentesis Thoracis) HYDROS ARC OCtfLE. (from wfyg, water ; ff increasing, and, from that moment, is disposed to diminish. This fact sufficiently evinces (continues this eminent Professors how important it is, in order to check the progress of the hypo- .pium, to employ, with the utmost care, the most effectual means for checking the attack of violent ophthalmy in its first stage. Copious evacuations of blood, both generally and topically, ought to be speedily pul in practice ; and when chemosis exists, the conjunctiva should be divided ; mild aperi- ents given, blisters applied to the nape of the neck, little bags of emollient herbs to the eye, and other measures employed. It Avill be known that they have fulfilled the indication, by noticing that, some days after the adoption of such treatment, though there may still be redness of the conjunctiva and eyelids, the lancinating pains in the eye abate, the heat considerably diminishes, the fever subsides, quietude and sleep are resto- red, the motion of the eye becomes free, and, lastly the collection of viscid matter forming the hypopium, becomes stationary. It is not unfrequent to see, especially among the lower orders of the people, persons affected with the second stage of severe acute ophthalmy, bearing this collection of coagulating lymph, in the chambers of the Vol. 11 14 aqueous humour, with the greatest indiffer- ence, and without complaining of any of those symptoms which characterize the acute stage of ophthalmy. It is only at this crisis, or at the termination of the acute stage of violent inflammation of the eye, that the enlargement of the hypopium ceases, and the coagulating lymph begins t® be absorbed, provided this salutary opera- tion of nature be not impeded, nor retarded, by any injudicious regitnen. However, if Scarpa had also been aware of the great efficacy of mercury, in arresting the effusion of lymph, I can hardly doubt, that he would have modified some of the preceding obser- vations, as well as his practice ; a subject t® which I shall presently advert again. Scarpa states, that persons, little versed in the treatment of diseases of the eyes, would fancy that the most expeditious and efficacious mode of curing an hypopium, after it has become stationary in the seeond stage of severe acute ophthalmy, would be that of opening the cornea at its most de- pending part, in order to procure a speedy exit for the matter collected in the chambers of the aqueous humour; especially as. this was once the common doctrine. But ex- perience shows, that dividing the cornea, in such circumstances, is seldom successful, and most frequently gives rise to evils, w'orse than t lie hypopium itseif, notwithstanding the modification suggested by Richter, ( Obs . Chir. Fasc. 1, Chap 12,) not to evacuate the whole of ihe matter at once, nor to promote its discharge by repeated pressure and in- jections, but to allow it to flow slowly out of itself. The wound made at the lower part of the cornea, for evacuating the matter of the hypopium, small as tbe incision may be, most commonly reproduces severe acute ophthalmy, and a greater effusion of coagu- lating lymph into the chambers of the aque- ous humour. Besides, after opening the cornea, if the matter of the hypopium w’ere allowed to escape gradually of itself, it would be several days in being completely discharged, on account of its viscidity. During this time, the glutinous lymph would keep the edges of the wound of the cornea dilated, and make them suppurate. Thus, the incision would be converted into an ulcer, through which the aqueous humour w r ould escape, and even a fold of the iris. Opening the cornea, therefore, only converts the hypopium into an ulcer of that mem- brane, attended with a prolapsus of the iris, and occasionally of the crystalline itself. Nor can any inference be drawn, in favour of making an artificial opening, during the stationary state of an hypopium in the second stage of severe acute ophthalmy, from the matter of the hypopium having sometimes made its way spontaneously through a narrow aperture in the cornea, with a successful result. For, there is a wide difference, betw'een the effects of a spontaneous opening in a natural, or preter- natural cavity of the animal body, or of one made with caustic, and the consequences of an opening, made with a cutting iastru- 10 6 HYPOPIUM. ment. In the two first methods, the subse- quent symptoms are constantly milder than in the last. Besides, even in the instance in which a spontaneous discharge of the hy- popium takes place through the cornea, an escape of the aqueous humour, and a pro- lapsus of the iris, not unfrequently ensues ; consequently, the spontaneous evacuation of the hypopium cannot justly form a rule for the treatment of the disease. There is only one case, in which dividing the cornea, in order to discharge an hypopium, is not only useful, but indispensable ; this is, when there is such an immense quantity of coagu- lating lymph extravasatea in the eye, that the excessive distention, which it produces of all the coats of this organ occasions symptoms so vehement, as not only threaten the entire destruction of the eye, but even endanger the life of the patient. But this particular case cannot serve (says Scarpa) as a model for the treatment of ordinary cases. The dispersion of the hypopium, by means of absorption, forms the primary indication, at which the surgeon should aim. In order to stop its progress, the most efficacious method is to subdue the first violence of the inflammation, and to shorten its acute stage, by the free employment of antiphlogistic treatment, and the use of mild emollient, topical remedies. And, in conjunction with these means, there can now be no doubt, that the practice of BrUel, published in 1809, as will be mentioned at the close of this article, ought to be followed : 1 mean, the quick exhibition of the submuriate of mercury, which has been also found at the London Eye Infirmary the most powerful means of checking the effusion of lymph in the eye. (See Saunders's fVork on the Eye, Ed. 2, and a Synopsis of the Diseases of the Eye , by B. Travers, p. 135.) If this treatment answer, the incipient collection of coagulating lymph, at the bottom of the anterior chamber of the aqueous humour, not only ceasestoaugment, but, also, in proportion as the severe ophthalmy disappears, the absorbent system takes up the heterogeneous fluid extravasa- ted in the eye, and the white,. or yellow speck, shaped like a crescent, situated at the bottom of the anterior chamber, gradually diminishes, and is at last entirely dispersed. Janin considered an infusion of the flowers of mallows, applied to the eye that is infla- med apd affected with this disease, as a specific resolvent in these circumstances, (M6m. et Obs. surVCEil, p. 405,) but it is now known, that every topical emollient applica- tion, provided it be conjoined with such internal antiphlogistic treatment, as is the most proper for repelling the acute stage of the severe ophthalmy, produces quite as good an effect as this infusion. Simple warm water produces the same benefit. A young girl (says Naenoni) was struck in the eye by an ear of corn. An inflamma- tion was the consequence, which produced a white pus of a semi-lunar shape, apparent- ly behind the cornea, without a possibility of judging whether the matter was actually- situated between the laminae of that mem- brane, or in the anterior chamber. Hence, I was asked, whether it might not be evacu- ated by an incision, particularly as the patient complained of great pain in the eye, and eyebrow. She was in the hospital ; and in the presence of Dr. Lulli, and several students in surgery, I said that the pain of which the patient complained, was not occa- sioned by the pus itself, but tbe cause which produced it. This cause was inflammation, which probably would be increased by making a larger opening for the external air, than wbat it has to the internal parts, while the external ones remain entire. By fomenting the eye and forehead with warm ■water, the inflammation subsided, and the pus disappeared. We have so often witness- ed tbe fact subsequently, that we can also extol the simplicity of the treatment.” Such, in short, is the successful termination of an hypopium, whenever the disease is properly treated at its commencement, and the acute stage of severe ophthalmy is promptly checked by internal antiphlogistic means, and emollient applications. But, in consequence of the inflammatory period of the severe ophthalmy having resisted, in an uncommon manner, the best means, or because such means have been employed too late, it sometimes happens, that the coagulating lymph, collected in the anterior chamber, is so abundant, even after the acute stage of ophthalmy, that it continues for a long time to cloud the eye, and inter- cept vision. Scarpa has often seen patients, especially paupers, who, from indolence, negligence, or ill treatment, remained a long time after the cessation of the inflam- matory stage of ophthalmy, with the anterior chamber almost entirely filled with the glutinous matter of hypopium. When the inflammation had ceased, these unhappy persons wandered about tbe streets almost quite indifferent, and without complaining of pain, or any other inconvenience, than the difficulty of seeing with the eye affected. In this second stage of the ophthalmy, the resolution of hypopium obviously cannot be accomplished by the same means, nor with equal celerity, as in the first. At this crisis, the great quantity and density of the gluti- nous matter extravasated, and the atony of the vascular system of the eye, make it necessary to give nature sufficient time to dissipate the thick, tenacious matter, and, at length, to dispose it to be insensibly absorbed with the aqueous humour which is continu- ally undergoing a renovation. Hence it is right, (says Scarpa) to adopt those means, which are best calculated to iavigorate the vascular system of the eye, more especially the lymphatics. This requires more or less time, according as the patient is advanced in years, of a relaxed fibre and weak ; or a young man of good constitution. However, according to Scarpa, in the second stage of violent acute ophthalmy, complicated with hypopium, the surgeon should limit his efforts to the rernovnl ot HtPOPIUM. 107 every thing, which may irritate the eye, or be likely to renew the inflammation ; and he should only employ such means, as are conducive to the resolution of the second inflammatory stage, depending on relaxation of the conjunctiva and its vessels, and such remedies as tend, at the same time, to invigo- rate the action of the absorbents. There- fore. i , this state, he ought first to examine carefully the degree of irritability in the eye. affected with the hypopium, by introducing, between the eye and eyelids, a few drops of vitriolic collyrium, containing the mucilage of quince seeds. Should the eye seem too strongly stimulated by this application, it must not be used, and little bags of warm mallows with a feu grains of camphor are to be substituted for it. In the intervals, the vapours of the liquor ammon. comp, may be applied, and recourse had again to a blister on the nape of the neck. When the extreme sensibility of the eye is overcome, the zinc collyrium must be used again, after- ward strengthened with a few drops of camphorated spirit. Under such treatment, proceeds Scarpa, the surgeon may observe, that, in proportion as the chronic ophthahny disappears, and the action of the absorbents is re-excited, the) tenacious matter of the hypopium divides first into several small masses ; then dissolves still further ; and, afterward, decreases in quantity : descend- ing towards the inferior segment of the cornea ; and, finally, vanishing altogether. But Scarpa accurately observes, tfiat the surgeon cannot always expect to be equally successful, whether the disease occur during the first, or second stage of violent acute opbthalmy, if the tenacious lymph, suddenly extravasated in the interior of the eye, prevail in such quantity, as not only to fill, but strongly distend, the two chambers of the aqueous humour, and the cornea in particular. In this state, notwithstanding the most skilful treatment, the unpleasant complication is often followed by another inconvenience, still worse than the hypopi- um itself; viz. ulceration, opacity, and burst- ing of the cornea. The ulceration of the cornea ordinarily takes place tvith such celerity, that the sur- geon seldom has time to prevent it. As soon as an aperture has formed, the exces- sive abundance of coagulating lymph, con- tained in the eye, (sometimes named em- pyema oculi) begins to escape through it, and a degree of relief is experienced. But, this melioration is not of long continuance ; for. scarcely is the glutinous fluid evacuated, that distended the. whole eye, and especially the cornea, when it is followed by a portion of the iris, which glides through the ulcera- ted aperture, protrudes externally, and con- stitutes the disease termed prolapsus of the iris. (See Iris, Prolapsus of.) But, if in such an emergency, the cornea already ulcerated, opaque, and greatly deranged in its organization, should not immediately burst, the surgeon is then constrained by the violence of the symptoms, depending on the prodigious distention of the eyeball, to make an opening in this membrane, in order to relieve the immense constriction, and even the danger in which life is placed. Were there the least chance of restoring, in any degree, the transparency of the cor- nea, and the functions of the organs of vision, after opening the cornea, Scarpa acknowled- ges that it would certainly be more prudent to make the opening at the lower part of this membrane. But in the case of empye- ma of the eye, now considered, in which the cornea is universally menaced with ulcera- tion and opacity, and seems ready to slough, there can be no hope of its resuming its transparency at any point, and he therefore decrns it the best and most expeditious me- thod of relief to divide its centre with a small bistoury to the extent of a line and a half; and then to raise with a pair of for- eeps the little flap, and cut it away all round with one stroke of the scissors, so as to let the humours escape without any pressure. The eye is to he covered with a bread and milk poultice, which is to be renewed every two hours, the use of such general remedies, as are calculated to check the progress of acute inflammation, and to quiet the nervous system, not being omitted. In proportion as the interior of the eye suppurates, the eye- ball gradually diminishes, shrinks into the orbit, and at length cicatrizes, leaving things in a favourable state for the application of an artificial eye. When Scarpa delivers his opinion, that in the above aggravated form of hypopium, there can be no chance of the cornea resu- ming its transparency at any point, I think his assertion rather imprudent. Nor. admitting its general truth, does it follow as a matter of course, that it is necessary and right to cut away a piece of the centre of the cornea, and absolutely destroy whatever little chance may yet be left of saving the eye. In sup- port of this remark, let me contrast what Mr. Travers has said with the advise of Scar- ps “ When the hypopium is so large as lo rise towards the pupil, and the ulceration of the cornea is extending, I think its discharge by section near its margin adviseable. If not too long delayed, the ulcerative process is checked by it, which would otherwise rrin into sloughing, and Ike cornea recover with only partial opacity and disfigurement." (Sy- nopsis of the Diseases of the Eye, p 2S0.) Mau chart de Hypopyo. Tubingw, 1742. C. P. Leporin, de Hypopyo. ilo. Goett. 1778. Gotldlin, Diss. de Hypopyo. Erlang. 1810. IV nit her Merkwiirdige Iieilung eines Eiter- auges, fyc.. 8t'o. Landsh.nl, 1819. I observe , that in Hufelahd and Himley's Journal for Oclob. 1809, p. 93, there is an account of the treatment of an hypopium, or case of effused lymph in the chambers of the eye, by exhibit- ing from 12 to 18 grains of the submuriate of mercury, in the space of 12 hours , and then giving bark, while as an external application the tinct. opii crocat. teas employed. Thus ue spe that the efficacy of mercury in checking the effusion of lymph in the eye , and promoting an absorption , has been known many years in Germany. A. Scarpa Saggio di Osservazioni Anatomy of the Human Eye, Chap. 6 . c d'Esperitnze, suite Principali Malaltie Edinb. 1 S 08 . degli Occhi; Venezia , 1802. Richter An- HYSTEROTOMIA. (from vo-ree,*., Ihe Jdngsgriinde der Wundarzneykunst , B. 3. womb, and rifj.vu>, to cut.) See Ccesartan 1705. ,/. Wardrop, Essays bn the morbid Operation. I. I VI PERFORATE HYMEN. (See Va- gina.) 1 NCARCEKAT10N. This term is usually applied to cases oi hernia in the same sense as strangulation. When the viscera are press- ed upon either by the opening through which they protrude, or by the parts them- selves within the hernial sac, in such a de- gree, that the course of the intestinal matter to the anus is obstructed, and n usea, sickness, pain, and tension of the swelling and abdo- men, &lc. are occasioned, the rupture is said to be in a slate of incarceration or strangula- tion. Accordingto Professor Scarpa, however, an incarcerated , and a strangulated hernia, do not imply exactly the same. thing. Inthefirst case, says he, the course of the intestinal matter is interrupted, without any considerable impair- ment of the texture, or vitality of the bowel. On the contrary, in the strangulated hernia, besides the obstruction to (he course of die fecal matter, there is organic injury of the coats of the intestine, with loss of its vitality. The bowel that is merely incarcerated, re- sumes its functions immediately it is replaced in the abdomen ; while that which is truly strangulated never returns to its natural state. ( Traite dcs Remits, p. 251.) This distinction, however, is by no means generally adopted. INCONTINENCE OF URINE. (See Urine, Incontinence of.) INFLAMMATION, (from inflammo, to burn.) By the term, inflammation, is gene- rally understood the state ot apart in which it is painful, hotter, redder, and somewhat more turgid than it naturally is ; which topical symptoms, when present in any considerable degree, or when they atfect very sensible parts, are attended with lever, or a general disturbance of the system. (Burns.) The susceptibility of the body for in- flammation is of two kinds ; the one origi- nal, constituting a part of the animal econo- my, and beyond the reach of human investi- gation ; the other acquired from the influence of climate, habits ot life, and state of the mind over the constitution. (Hunter.) The lirst kind of susceptibility being innate, can- not be diminished by art ; the second may be lessened by the mere avoidance of the par- ticular causes upon which it depends. Inflammation may, with great propriety, be divided into healthy and unhealthy. Of the first, there can only be one kind, though di- visible into different stages ; of the second, there must be an infinite number of species, according to the peculiarities of different GO n$tftutions, and the nature of diseases which are numberless. (Hunter.) Another general division is into common and specific inflammation, the latter lurm implying, that the affection has some strongly marked par- ticularity about it, rendering it in some de- gree independent of such circumstances as would control and regulate the progress of common inflammation. Such are venereal , variolous, vaccine, erysipelatous, gouty , and rheumatic inflammation^, &. c. Inflammation may ;»lv> be divided into the acute and chro- nic. This division of the subject is one of the most ancient, and seems to have obtain- ed the. sanction of all the best surgical wri- ters. Healthy inflammation is invariably quick in its progress, for which reason, it must always rank as an acute species of the affection. However, there are numerous in- flammation-, controlled by a diseased princi- ple, which are quick in their progress, and are, therefore, to be considered as acute. Chronic inflammation, which will be treated of when 1 come to the subject of tumours , is always accompanied with diseased action. My friend, Mr. James of Exeter, justly impressed with the utility which would re- sult from a good nosological arrangement of inflammation, has lately attempted to .supply what must generally be allowed to be a great desideratum. To the division of inflamma- tion into the acute, subacute , or chfonic, be o jeets, that in many instances, these are merely different stages of the same disease. The arrangement into the adhesive, suppura- tive, ulcerative, or gangrenous inflammation, be does not altogether approve, because it is merely founded on the modes in which either different, or in some instances, the same kinds of inflammation terminate. Un- der the heads of phlegmonous, erysipelatous , and gangrenous inflammation, he argues, that diseases of the most opposite nature have been indiscriminately brought together. The disposition to terminate in gangrene, he ad- mits, will afford a basis for subdivision, but not for primary separation. Mr. Janies makes some judicious observations on the arrangement of the kinds of inflammation, according to the elementary tissue in which they occur, as proposed by Dr. Carmichael Smith, JPinel, and Bichat." The tissues in question are five, and ihe doctrine supposes, that the inflammation of each is essentially different. The first is phlegmonous inflamma- tion, which affects the cellular membrane, including the parenchyma of the several vis- cera. The second is inflammation of serous membranes. The third, of mucous mem- branes. The fourth, which is named erysi- pelatous, is of the skin. And the fifth, term- INFLAMMATION. 109 cd rheumatic, belongs to fibrous structure. That in Summations differ materially from tfie circumstance of their affecting one of these elementary tissues, rather than another, Mr. James freely admits: but the following objections appear to him fatal to this system, if they are tru<‘. 1. Different kinds o i in- flammation are liable to occur in the same tissue. 2. The same kind of inflammation is often met aith iti different tissues. 3. The same inflammation may be transferred from one to another; an argument, however, on which he lays less stress, as being difficult of direct proof. (S e Obs. on the different Species of Inflammation, p. 3 — 7 8 vo. Lond. 1821.) At though difference of structure un- questionably accounts for some of the varie- ties in the appearance and character of in- flammation, it will not sufficiently explain the principal diversities of this affection to be taken s the foundation of a nosological arrangement, not only for the reasons pointed out by Mr. James, r>u ; because the common distinctions of inflammation at present in vogue, arid some of which at least are ob- vious and striking, cannot be at all solved by any reference merely to texture. N >r did this theory satisfy Mr. Hunter, who observed, that if it were true, “ we should soon be made acquainted with all the different in- flammations in the same person at be same time, and even in the same wound. For in- stance, in an arnpui *tion of a leg, where we cut through the -kin, cellular membrane, muscle, tendon, periosteum, bone, and mar- row, the skin should ;ive us inflammation of its kind, the cellular membrane of its kind ; the muscles of theirs, h &c. but we find it is the same i iflammation in them all. How- ever, though Mr. Hunter did not ad. nil the possibility >t referring the different kinds of inflammation to peculiarities of texture, his doctrines assign to this cause considerable influence over every form of the disorder, as will be presently explained. The mode of reasoning adopted by Mr. James, leads him to propose ; 1-t. The divi- sion of inflammations into two great classes, according to their disposition either to be li- mited by the effusion of organizable coagu- lable lymph, or to spread. 2 , which are not what anatomists verm vascular , seem to enjoy only inferior pow- ers of life, and, consequently, when excited in a preternatural degree, frequently mor- tify. But, inflammation of vital parts, though they may be exceedingly vascular, cannot go on so favourably, as in other parts of re- sembling structure, but, of different func- tions ; because, the natural operations of universal health depend so much upon the sound condition of such organs. (Hunter.) The truth of this observation is illustrated in cases of gastritis, peripneumony, he. All new-formed parts not originally en- tering into the fabric of the body, such as tumours, both of the encysted and sarcoma- tous kinds, excrescences, he. cannot en- dure the disturbance of inflammation long, ror in a great degree. The vital powers of such parts are weak, and when irritated by the presence of inflammation, these adven- titious substances are sometimes removed by the lymphatics, but more commonly slough This remark applies also to sub- stances generated as substitutes for the ori- ginal matter of the body ; for instance, granulations and callus The knowledge of this fact, leads us to a rational principle of cure in the treatment of several surgical diseases. Do we not here perceive the cause, why very large-wens are occasion- ally dispersed by the application of urine, brine, and similar things, which are now in great repute, on this account, with almost every one out of the profession ? How many verruca?, wrongly suspected to origi- nate from a syphilitic cause, are diminished and cured by a course of mercury ! It is the stimulus of this mineral upon the whole system, that accomplishes the destruction of these adventitious substances — not its antivenereal quality. Topical stimulants vouid fulfil the same object', not only with greater expedition, but with no injury to the general health. Inflammation, cceleris paribus , always pro- ceeds more favourably in strong, than in weak constitutions; for, when there is much strength, there, is little irritability. In weak constitutions, the operations of in- flammation are backward, notwithstanding the part in which it is seated may, compa- ratively speaking, possess considerable or- ganization, and powers of life. (Hunter.) Healthy inflammation, wherever situated, is always most violent on that side of the point of inflammation, which is next to the external surface of the body. When in- flammation attacks the socket of a tooth, it does not take place on the inside of the al- veolary process, but towards the cheek. When inflammation attacks the cellular sub- stance, surrounding Ihe rectum, near the anus, the affection usually extends itself t® the skin of the buttock, leaving the intes- tine perfectly sound, though in contact with the inflamed part. (Hunter.) We may observe the influence of this law in the diseases of the lachrymal sac and duct, in those of the frontal sinus and antrum, and particularly in-gunshot wounds. Suppose a ball were to pass into the thigh, to within an inch of the opposite side of the iimb we should not find, that inflammation would be excited along the track of the ball, but, on the side next ihe skin which had not been hurt. If a ball were to pass quite through a limb, and carry into the wound a piece of cloth, which lodged in the middle, equidistant from the two orifices, the skin, immediately over the extraneous body, would inflame, if the passage of the ball were superficial. — (Hunter) Mr. Hunter compared this law with the principle, by which vegetables approach ihe surface of the earth ; but, t ee solution ot it was too arduous even for his strong genius and pene- tration. We see three very remarkable effects follow the prevalence of inflammation ; viz. adhesions of parts of the body to each other; the formation of pus, or suppura- tion ; and ulceration, a process, in which the lymphatics are more concerned, than the blood-vessels. Hence, Mr. Hunter termed the different, stages of inflammation, the adhesive, the suppurative, and the ulcer- ative. All parts of the body are not equally lia- ble to each of the preceding consequences, (Hunter.) INFLAMMATION’. Ill In the cellular membrane, and in the cir- cumscribed cavities, the adhesive stage takes place more readily than the others ; suppuration may he said to follow next in order of frequency ; and lastly ulceration. In internal canals, on the inner surfaces of the eyelids, nose, mouth, and trachea, in the air-cells of the lungs, in ihe oesophagus stomach, intestines, pelvis of the kidney, ureters, bladder, urethra, and in all the ducts and outlets of the organs of secretion, being what are termed mucous membranes , the sup- purative inflammation comes on more rea- dily, than either the adhesive, or the ulcer- ative stage. Adhesions, which originate from the slightest degree ot inflammation in other situations and structures, can only be produced by a violent kind in the above- mentioned parts. Ulceration is more fre- quently met with upon mucous surfaces, than adhesions. (Hunter.) The cellular membrane appears to be much more sus- ceptible of the adhesive inflammation, than the adipose, and much more readily passes into the suppurative. (Hunter ) Thus we see the cellular substance, connecting the muscles together, and the adipose mem- brane to the muscles, inflaming, suppurating and the matter separating the muscles, from their lateral connexions, and even the fat from the muscles, while the latter substance and the skin are only highly inflamed. (Hunter.) But, it must be allowed, that in situations where fat abounds, we very fre quently meet with abscesses. This is so much the case, that fat has been accounted a more frequent nidus for collections of matter, than the cellular substance. (Brom- Jield.) Abscesses are particularly liable to form in the neighbourhood of the anus, mamma, &c. With respect to the fat being highly inflamed, however, the expression is not strictly true. Fat has no vessels, princi- ple of life nor action of its own ; conse- quently, we cannot suppose that it can itself either inflame, or suppurate. We know', that it is itself a secretion, and when an ab- scess forms in it, vve understand, that the mode of action in the vessels, naturally des- tined to deposit fat, has been altered to that adapted to the formation of pus. When therefore the fat is said to be inflamed, it is only meant, that the membranous cells, in which it is contained, and by which it is se- creted, are thus affected. The deeply-situated parts of the body, more especially the vital ones, very readily admit of the adhesive stage of inflammation The circumstance of deeply-seated parts not so readily taking on the suppurative stage of inflammation, as the superficial ones do, is strikingly illustrated in cases of extraneous bodies, which, if deeply lodged, only produce the adhesive inflammation. By this process, a cyst is formed, in which they lie without much inconvenience, and they may even gradually change their situa tion, without disturbing the parts, through which they pass. But, "no sooner do these same bodies approach the skin, than absces- ses immediately arise. (Hunter.) All inflammations, attended with disease, partake of some specific quality, from which simple inflammation is entirely free. When the constitution allows the true adhesive and suppurative stages to occur, it is to be regarded as the most healthy. Were it in an opposite state, vve should see the very same irritation excite some other kind of inflammation, such as the erysipelatous, scrofulous, &c. (Hunter.) In specific inflammations, the position, structure, and distance of the part affected from the source of the circulation, as well as from t lie surface of the body, seem also to have as much influence as in cases of common inflammation. Upon this point, I feel conscious of being a lit'le at variance with what Mr. Hunter has stated ; but, the undecided manner in which he expresses himself, not less than the following reflec- tions, encourages me not to desert my own ideas. We see, that venereal eruptions sooner make their appearance upon the chest and face, than upon the extremities. No organized part can be deemed exempt from the attack of common inflammation ; many appear to be totally insusceptible of the venereal. We know, that scrofulous dis- eases of tiie superior extremities take a more favourable course, require amputation less frequently, and get well oftener than when situated in the inferior limbs. (Ford.) The venereal disease makes more rapid advan- ces in the skin and throat, than in the bones and tendons ; we often see it producing a specific inflammation, and an enlargement of the superficial parts of the tibia, ulna, clavicle, cranium, &,c. while other bones, covered by a considerable quantity of flesh, are very rarely affected. Gouty inflamma- tion is prone to invade the small joints ,j rheumatic, the large. SYMPTOMS, NATURE, AND CAUSES OF INFLAM- MATION. Redness, swelling, heat, and pain, the four principal symptoms of phlegmonous inflam- mation, have been accurately noticed by Celsus : Notce vero injlammationis surd qua- tuor, rubor, et. tumor, eum calore et dolore , lib. 3, cap. 10. If we refer to any writer on this interesting part of surgery, we shall find the above symptoms enumerated as characteri- zing phlegmon. In short, this term is usu- ally applied to a circumscribed tumour, at- tended with heat, redness, tension, and a throbbing pain. These are ihe first appear- ances observed in every case of phlegmon ; and when they are slight, and the part af- fected is of no great extent, they have com- monly very little, and sometimes no appa- rent, influence on the general system. But when they are more considerable, a id the inflammation becomes extensive, a full, quick, and generally a hard pulse takes place, and the patient, at the same time, complains of universal heat, thirst, and other symptoms of fever. While the inflamed part becomes red, painful, and swelled, its func- tions are also impaired. The same degree 112 INFLAMMATION. of inflammation is said to produce more swelling in sol. parts, and less in those of a harder structure. {Burns.) Though the redness, swelling, throbbing, tension, and other symptoms of phlegmo- nous inflammation, are less manifest, when the affection is deeply situated, yet their ex isterice is undoubted. When persons die of peripneumony, or inflammation of the lungs, the air-cells of these organs are found crowded with a larger number of turgid blood-vessels than in the healthy state, and of course the parts must appear preternatu- rallv red. Coagulating lymph, and even blood, are extrav. sated in the substauce of these viscera, which become heavier, and feel more solid. ( Bnillie .) The extravasation of coagulating lymph, which is one of the chief causes of the swell- ing, is also one of the most characteristic signs of phlegmonous inflammation. Some writers (Smith, in Med. Commun. Vol. 2.) have confined the seat of phlegmon to the cellular membrane ;• but this idea is erroneous. Had such authors duly discrimi- nated the nature of common inflammation, they would have allowed that this affection existed, wherever the capillaries appeared to be more numerous and enlarged '.nan in the natural state, accompanied with an effu- sion of coagulating lymph, whether upon the surface of a membrane, or a bone, or into the interstices of the cellular substance, and attended with acute pain, and a throb- bing pulsation in the part. As Dr. Thomson has observed, the epithet remote as applied to the causes of inflamma- tion. does not appear to be happily chosen ; for under this term are comprehended all those agents, evtents, and states, which con- tribute "immediately, as well as remotely, directly as well as indirectly, to the produc- tion of the affection. ( Lectures on Inflam- mation, p. 50.) The remote causes of inflammation are infinite in number, but very easy of com- prehension, because orny divisible into two general classes. The first includes all such agents as operate by their stimulant or chyrnfcal qualities; for instance, canthari- des, heat, the action of concentrated acids, alkalies, metallic oxides, and metallic salts, acrid vapours, such as ammoniaeal gas, the nitrous, sulphureous, muriatic, oxygenated muriatic gases, &vc. alcohol, aether, and all acrid vegetable essential oils, animal poi- sons, and the whole of that class of substances known by the name of rubefacients. ( Thom- son on Inflammation, p. 55.) The second class of causes are those which act mechanically, such as bruises, wounds, pressure, friction, fcc. Fevers often seem to become the remote causes of local inflammation, in other in- stances, inflammation appears to arise spon- taneously, or, as I should rather say, without any perceptible exciting cause. The principle on which the application of cold to a part becomes the remote cause of inflammation, is not decidedly known. “ No sublet (says a distinguished professor) is more deserving of your study, than the effects which are produced in the human body by the operation of cold applied to its surface ;but the subject is, at the same time, exceedingly extensive, complicated, and dif- ficult. .These effects differ according to the degree in which the cold is applied, the state of the system, the part of the body to which it is applied, and the mode of its ap- plication. So diversified, indeed, are these effects, that it requires no mean confidence in theoretical reasoning to believe, that the operation of cold in producing them is ex- plicable upon any single general principle.’' (See Thomson on Inflammation, p. 58.) And in the preceding page, he observes: “The operation of cold upon the human body af- fords the best example which 1 can suggest to you. of the production of inflammation from the operation of a power acting upon a part at a distance from that in which the inflammation takes place. The instances formerly mentioned of inflammation of the throat, chest, or belly, from the application of cold to the feet, are daily occurrences in these climates, of which it is impossible for us, in the present stale of o ir knowledge of the animal economy, to give any thing like a satisfactory explanation. “ In some instances, cold, or a diminution of temperature, seems to act more directly upon the parts, with which it comes into contact. We have examples of this in the inflammation of the mucous membranes of the nose, fauces, trachea and bronchia?, from the inhalation of cold air; and in the production of rheumatic inflammation from the accidental exposure of some part or other of the body to cold. The application of cold, in the instances I have mentioned, seems to have somewhat of a directly exci- ting effect ; and perhaps the same remark is still more applicable to the local effects of cold in the production of the inflammation accompanying the state, which is usually denominated fast-bite. Touching a solid body, as a piece of metal, the temperature of which has been greatly reduced, produces a sensation like that of burning, and maybe folhmed, like the application of fire, with a blister.” (Op. cil.) Numerous opinions have been entertain- ed respecting die proximate cause of Inflam- mation ; but almost every theory has been built upon the supposition of there being some kind of obstruction in the inflamed part. While the circulation of the blood was unknown, and the hypothetical notions of the power of the liver, in preparing and sending forth this fluid, continued to prevail, physicians were so fully persuaded of the existence and influence of different humours and spirits, and so little did they know of the regular and constant motion of the blood, that they believed in the possibility of depositions and congestions of the blood, the bile, or lymph ; and acknowledged these as the cause of inflammation. I heir anato- mists taught them, and their professors <*1 physic supported the opinion, that the liver INFLAMMATION. 113 was the centre of the vascular system, from which the blood went forth by day to the extremities, and returned again by night. If then any peccant matter irritated the liver, the blood was sent out more forcibly ; and if, at the same time, any part of the body were weakened, or otherwise disposed to receive a greater quantity of fluid than the rest, then a swelling was produced by ihe flow of humosrs to this place. Fluxions, or flows of humour to a place, might happen cither from weakness of the part which al- lowed the humours to enter more abun- dantly, or from the place attracting the hu- mours, in consequence of the application of heat or other agents. The peculiar nature of the swelling w as supposed to depend upon the kind of humour. Blood produced the true phlegmon ; bile, erysipelas ; &c. An idea was also entertained, that the blood and humours might slowly stagnate in a part, from a want of expulsive power, and this affection w as termed a congestion, w hile the expression fluxion or defluxion was used to denote any swelling arising from the sud- den flow of humours from a distant part. (J. Burns , Dissertations on Inflammation.) From the theories of fluxion and conges- tion, which were quite incompatible with the laws of the circulation of the blood, we turn our attention to the doctrine of ob- struction. Boerhaave inculcated, (Jlph. 375 el seq.) that inflammation w as caused by an obstruc- tion to the free circulation of the blood in the minute vessels, and this obstruction, he supposed, might be caused by heat, diar- rhoea, too copious flow of urine, and sweat, or whatever could dissipate the thinner parts of the blood, and produce a thickness or viscidity of that fluid. When the lentor did not exist before the production of inflamma- tion, he imagined that the larger globules of the blood passed into the small vessels, and thus plugged them up. This circum- stance was termed an error loci. The ob- struction, whether caused by viscidity or an error loci, was imagined to occasion a resist- ance to the circulation in the part affected ; and hence, an increase of the flow of the blood in the other vessels, an irritation of the heart, and augmentation of the force, or attraction of the blood in that part of the vessel which was behind the obstruction. This caused heat and pain, while the accu- mulation of blood produces redness. Bo- erhaave also brought into the account an acrimonious stale of the fluids, which render- ed resolution out of the question, and gan- grene likely to follow. (Jlph. 388.) The viscidity of the blood cannot be ad- mitted as the proximate cause of inflamma- tion ; because we have no proof that this state ever exists ; or, granting that it did, it would not explain the phenomena. Were a viscidity to occur, it would exist in the whole mass of blood, would affect every part of the body alike, and could not be sup- posed to produce only a local disorder. How also could such a lentor be produced by causes which bring on inflammation sud- Vot.. TT 15 denly, without there being time for changes of the fluids to take place ? With regard to the doctrine of error loci , or of red globules going into vessels which did not formerly transmit them, the fact must be admitted, at the same time, that the conclusion is denied. When the eye be- comes inflamed, the tunica conjunctiva is seen with its vessels full of red blood, which in health is not the case; but this redness never appears until the inflammation has commenced, and must therefore be consi- dered as an effect, not a cause. Nor can this error loci occasion any obstruction in these vessels ; for if they be divided, the blood flows freely, which shows that they are large enough to allow an easy circula- tion. (J. Burns.) Boerhaave’s theory of obstruction was too circumscribed, and too mechanical ; it re- duced all inflammations to one species: the only distinctions which could have arisen, must have proceeded from the nature of the obstruction itself ; and it was a doctrine that never could account for the action of many specific diseases and morbid poisons. (Hun- ter.) As for the supposition of the co-operation of an acrimony of the fluids, the proportion of the saline matter of the blood has never been proved to be greater in this, than in. any other state of the body. (Burns.) Even were a general disorder of this kind to be admitted, no rational explanation of the proximate cause of local inflammation could be deduced from it. The decided impossibility of giving a ra- tional explanation of the immediate cause of inflammation by any supposed state of the blood alone, led pathologists to investi- gate how far a change in the blood-vessels themselves might account for the process. It belongs more properly to a physiological than a surgical work, to explain the various facts and experiments in support of the opi- nion, that the arterial tubes, and especially the capillaries, possess a high degree of vital contractility, whereby the motion of the fluids in them, the process of secretion, and other local phenomena may be importantly affected, in a manner not at all explicable, by reference only to the action and power of the heart. For such information,! would particularly advise the x-eader to consult the publications of Dr. Wilson Philip, and Dr. Hastings. Accoi’ding to the latter gentle- man, the actual agency of the capillaiy ves- sels, “ is not only supported by such ex- periments as those related, it is also coun- tenanced by an extensive series of pheno- mena presented during disease in the hu- man subject. Of these may be mentioned, irregular determinations of blood, the growth of tumours, increased pulsation of arteries leading to inflamed parts, of which the fol- lowing is a well-marked example, the accu- racy of which may be entirely relied upon. The carotids, when the person alluded to is in health, beat equally as to strength and frequency; but when he is attacked with inflammation in the right tonsil, to which 114 INFLAMMATION. he is particularly subject, and which pro- ceeds sometimes so far as nearly to prevent deglutition, each pulsation of the artery gives a throbbing sensation on the right side of the head. On the application of the hand at this time to each carotid, the right is found to beat much stronger and fuller than the left. This diversity of action in these two arteries cannot arise from any impulse given by the blood to the heart : it must be derived from some modification of the contractile power of the artery.” And Dr. Hastings expresses his belief in this ex- planation, notwithstanding Dr. C.H. Parry wishes to attribute to the remote influence of the heart some of the phenomena of local congestion and motion, and to show, that the different states of vascular dilatation are still more conspicuously connected with the different degrees of action of the heart, and the consequent momentum of the blood, than with local circumstances ; and that the proneness to local dilatation, or, as it is called, action, is a consequence of slowly succeeding, but continued impulse The blood-vessels, through every part of the system, possess a considerable share of irritability, by which they contract, and pro- pel forward their contents. Hence, the blood, by the action of the vessels, receives a new impulse in the most minute tubes, and a well-regulated momentum is preser- ved in every part of its course. But of all parts of the sanguiferous system, the capil- laries seem most eminently endowed with this faculty, and are least indebted to the presiding influence of the heart. Yet even in these vessels, the action of the heart is of high importance in sustaining the healthy circulation, inasmuch as it gives the first impulse to the blood, and preserves the har- jnony of the sanguiferous system. The vessels are endowed with this vital property, in order that each organ in the body may receive such a supply of blood as will enable it duly to exercise its func- tions. Hence, a healthy state of this pro- perty is absolutely necessary for the preser- vation of the animal functions ; for, if the vital contraction* of the blood-vessels be either increased or diminished, irregular distribution of the blood inevitably follows, and from this source numerous diseases arise, and none more frequently than in- flammation. However, though these senti- ments, delivered by Dr. Hastings, may be generally correct, 1 am not prepared to join in the opinion, that inflammation is ever produced simply by an inequality in the distribution of the blood ; a statement which this gentleman probably does nut mean to make himself, as he confesses that some of the phenomena of this disease de- pend upon sympathy between the sanguife- rous and nervous systems. (See Hastings on Inflammation of the Mucous Membrane of the Lungs, p. 32, 64, 65, 8 vo. Lond. 1820; and C. H Parry, Additional Experiments on the Arteries , fyc.p. 112, 114 ; Also Why 1 1 on the Motion of the Fluids in the small Vessels ; Yerscfiuir dr. Arteriarvm et Venarum vi irri • tabiti ; Zimmermann de irritabilitatc, p. 24 j Hunter on the Blood , «^c.) Dr. Cullen attributed the proximate cause of inflammation to a “ spasm of the extreme arteries supporting an increased action in the course. of them.” This theory only dif- fers from that of Boerhaave in the cause which is assigned for the obstruction, Dr. Cullen conceived, however, that some causes of inequality in the distribution of the blood might throw an unusual quantity of it into particular vessels, to which it must necessarily prove a stimulus ; and that, in order to relieve the congestion, the vis me- dicatrix naturae increases still more the action of the vessels ; which, as in all other febrile diseases, it affects by the formation of a spasm on their extremities.” “ A spasm of the extreme arteries, supporting an in- creased action in the course of them, may, therefore be considered as the proximate cause of inflammation ; at least, in all cases not arising from direct stimuli applied ; and even in this case the stimuli may be suppo- sed to produce a spasm of the extreme vessels” (Cullen.) The inconsistencies in Cullen’s theory are very glaring. The congestion or accumula- tion of blood, which is only an effect or con- sequence of inflammation, is set down as the cause of the spasm of the vessels to which spasmodic constriction Cullen, strangely enough, assigns the name of proxi- mate cause. The spasmodic contraction of the extremities of the vessels, instead oi propelling the accumulated quantity ot blood, would render Ihe passage of the blood from the arterial into the venous sys- tem still more difficult. (Burns.) We shall now notice the celebrated and very original opinions promulgated on this subject by John Hunter. According to him, inflammation is to be considered only as a disturbed state of parts, which requires a new but salutary mode of action to restore them to that state wherein a natural mode of action alone is necessary. From such a view of the subject, therefore, inflammation in itself is not to tie considered as a disease, but as a salutary operation, consequent either to some violence or some disease. F.lsewhere the author remarks, the act of in- flammation is to be considered as an increa- sed action of the vessels, which , at first, consists simply in an increase or distention beyond their natural size This increase seems to de- pend upon a diminution of the muscular power of the vessels, at* the same time lhat the elastic power of the artery must be di- lated in the same proportion. This is, therefore, something more than simply a com- mon relaxation : we must suppose it an action in the parts to produce an increase of size for particular purposes, and this Mr. Hunter would call an act of dilatation. The whole is to be considered as a necessary operation of nature. Owing to this dilata- tion, there is a greater quantity of blood cir- culating in ihe part, which is according to the common rules of the animal economy ; for, whenever a part has more to do thfpi INFLAMMATION 1 . 115 Simply to support itself, the blood is there collected in larger quantity. The swelling is produced by an extravasation of coagula- ble lymph, with some serum : but this lymph differs from the common lymph, in consequence of passing through inflamed vessels. It is this lymph which becomes the uniting medium of inflamed parts ; ves- sels shoot into it ; and it has even the power of becoming vascular itself. The pain pro- ceeds from spasm. The redness is produ- ced either by the arteries being more dila- ted than the veins, or because the blood is not changed in the veins. “ As the vessels become larger, and the part becomes more of the colour of blood, it is to be supposed there is more blood in the part ; and as the true inflammatory colour is scarlet, or that colour which the blood has when in the arteries, one would from hence conclude either that the arteries were principally di- lated, or, at least, if the veins are equally distended, that the blood undergoes no change in such inflammation in its passage from the arteries into the veins, which I think (says Mr. Hunter) most probably the case ; and this may arise from the quickness of its passage through those vessels .” When a part cannot be restored to health, after injury, by inflammation alone, or by adhe- sion, then suppuration, as a preparatory step to the formation of granulations, and the consequent restoration of the part, takes place. The vessels are nearly in the same state as in inflammation ; but they are more quiescent, and have acquired a new mode of action. (Hunter.) With respect to Mr. Hunter’s theory, which has deservedly had vast influence in regulating the judgment of professional men in this country, on the nature of the process called inflammation, it cannot be received in the present state of knowledge without some limitation. The hypothesis, that the blood-vessels possess an active power of dilatation, independently of their elasticity, as Dr. Hastings observes, must as yet be regarded as devoid of proof, and therefore should not be assumed as a basis on which any theory of inflammation is founded. (On Inflammation of the Mucous Membrane of the Lungs, fyc p. 70. ) And, as another intelligent writer remarks, how dif- ferent would have been Mr. Hunter’s infer- ences, if, instead of trusting to the unassisted eye, he had viewed the inflamed vessels through the microscope. He would then have seen the blood moving, and found, that, “ instead of its passage being quickened in the inflamed vessels , it is uniformly render- ed s ower in proportion to the degree of in- flammation. and, in the most inflamed parts, stands still altogether .” (On the Vital Func- tions, p. 288, Ed. 2.) And. in another part of his writings, Dr. Philip has endeavoured to prove, from several facts respecting the colour of the blood, that within certain limits , the accumulation of this fluid in the debilitated vessels of the inflamed part neces- sarily causes the blood to retain the florid, colour. (On Fevers, Part 2, Introd .) In modern times, the vague, but conve- nient expression, increased action of the ves- sels. has been very generally used as an adequate explanation of the proximate cause of inflammation. The doctrine, it is said, derives support from a review of the several exciting causes of the affection, which, be- ing in general of an irritating nature, must, when applied to any living or sensible parts, occasion such increased action of the ves- sels ; while the method of cure also tends to confirm the opinion. But, before one can judge whether this doctrine is correct, and supported by facts and observation, it is necessary to understand precisely what is implied by increased action of vessels; for it is not every affection of the vessels, capa- ble of being thus denominated, which will of itself constitute inflammation. In gesta- tion, the arteries of the womb are enlarged, and a greater quantity of blood is sent into them; yet this organ is not inflamed. The carotids are in a similar state during, the growth of the stag’s horn ; but no inflam- mation exists, if then the proximate cause of inflammation is to be called an increased action of the vessels, we must first be in- formed not only what is meant by the term, but what particular vessels are spoken of, whether the arterial trunks, bio chc's, or capillaries ? Because, if the phrase is intend- ed to signify increased alternate expansions and contractions of all the arteries of the inflamed part, it is an hypothesis entirely destitute of foundation. If it be meant to denote an increased velocity of the mo- tion of the blood in the part affected, the doctrine is rather contradicted than con- firmed by the latest and most carefully insti- tuted microscopical experiments. But if the expression onlyrefers to the dilated state of the capillaries, the throbbing of the arte- ries leading to the seat of inflammation, the effusion of lymph, &c. less fault can be found with the language, though yet requiring much further explanation ere it can com- municate any very precise information. “ There are (says a learned professor) two hypotheses, which at present divide the opinions of pathologists respecting the state of the capillary vessels affected with in- flammation. According to the first of these hypotheses, the inflamed vessels are in at state of increased action ; according to the second, they act with less force than the trunks from which they are derived.” (See Thomson on Inflammation, p. 64.) The first of these opinions, according to Dr. Thomson, was suggested by the views which Stahl took of the animal economy, and his ideas respecting the tonic or vital action of the capillary vessels. The doc- trine, however, was more particularly insist- ed upon by his disciples and followers, especially Dr. Gorter, who in one place expressly states, u that the proximate cause of inflammation consists in an increased vital action of some particular artery or arteries, by which the blood is propelled with greater fofce than usual into the com- mimic ating lymphatic and colourless vete INFLAMMATION. lit) sels.” (See his Compendium Medicines and Chirurgia Repurgala ) The doctrine which supposes the action of the inflamed vessels to be diminished, or to be proportionably less than that of the trunk or trunks from which they are deri- ved, was, as far as Dr. Thomson can learn, first stated by Vacca, an Italian physician, in a small treatise on inflammation, publish- ed at Florence in 1765, entitled “ Liber de Inflammat ionis Mo/bosce, quae in humano car- port fit natur&y causis, effedibus , el curatione .” For an account of the arguments with which Vacca supports his hypothesis, my limits oblige me to refer to the work of Dr. Thomson. (P. 68. <^c.) As this gentleman has observed, there are certain points in which the two doctrines agree, as well as in which they differ. “ The advocates for each hypothesis agree in admitting, 1st, that inflammation has its seat in the capillary vessels ; and 2dly, that the redness in inflammation is owing to an unusual quantity of blood in the vessels of the inflamed part, and consequently that the capillary arteries are much dilated du- ring the state of inflammation. The con- tractions of these vessels, indeed, it has been said, are increased also in a ratio pro- portional to the dilatations ; but, this is an assertion which has not yet been proved, either in the way of experiment or of ob- servation. “ The sense of throbbing, which the advo- cates for the hypothesis of increased capilla- ry action regard as the strongest proof of that action, Mr. Allen is disposed to attribute to the difficulty, which the blood meets with in passing from the trunk into the capillary branches. This sensation of throbbing, and appearance of increased action, may be produced in an instant, by applying a liga- ture to an uninflamed finger, so as to ob- struct the motion of the blood through its point. Besides, this throbbing, or pulsatory motion, can afford us no criterion, by which to judge of (he force, with which the artery contracts, for, it is produced in the dilatation of the artery, and by a power foreign to the artery itself.” ( Thomson on Inflammation , P- 73.) Dr. Wilson Philip, many years ago, en- deavoured to ascertain, by means of the microscope, the state of the vessels in the various stages of inflammation, both in the Warm and cold blooded animal. I have put the epithet warm in Italics, because it has been very recently observed by my friend Mr James, that “ analogies between the higher and lower orders of animals, the chief subjects of these experiments, cannot be deemed conclusive.” (On some of the General Principles of Inflammation, p. 29, 8 vo. Lond. 1821) as if it had escaped atten- tion, that many of the experiments were really made on the more perfect animals. From the valuable observations, to which 1 here allude, (See Philip on Febrile Diseases , Part 2, Inlrod.) it appears, that the state of the smaller vessels in an inflamed part is that of preternatural distention and debility. As for the larger vessels, whose state rnay be ascertained, without the aid of the micro- scope, “they do not undergo a similar dis- tention, and the increased pulsation of the arteries sufficiently evinces their increased action. In inflammatory affections of the jaw and the head, for example, a greatly in- creased action of the maxillary and temporal arteries is readily perceived by the finger. It is to be observed, however, that, although inflammation, as was evident from the fore- going experiments, begins in the capillaries, if it continues, the circulation in the smallest vessels becoming very languid, those imme- diately preceding them in the course of the circulation begin to be distended, and conse- quently debilitated.” Dr. Philip adds, that such distention and debility of the vessels, which immediately precede the capillaries, cannot go far, because when the former lose their power, the circulation in the latter is not supported, and gangrene soon ensues. “ In short, (says Dr. Philip) inflammation seems to consist in the debility of the capillaries , followed by a i increased action of the larger arteries ,” and is terminated by resolution, when the capillaries sere so far excited, and the larger arteries so far weakened, by the preternatural action of the latter, that the power of the capillaries is again in due proportion to the vis a tergo. “ Thus far, (says Dr. Philip) I cannot help thinking the nature of inflammation appears sufficiently evident. The motion of the blood is retarded in the capillaries, in conse- quence of the debility induced in them ; an unusual obstacle is thus opposed to its motion in the arteries preceding them in the course of the circulation ; which are thus excited to increased action. Several difficulties, however, remain, on which the experiments just related throw no light. Why does a failure of power, of small extent in the ca- pillaries of a vital part, strongly excite, not only the larger arteries of the part affected, bur those of the whole system ; while a more extensive debility of the capillaries of an external part excites less increased action in the larger arteries of that part, and often none at all in those of the system in general ? Why does inflammation often move sudden- ly from one part to another, when we see no cause, either increasing the action of the capillaries of the inflamed part, or weaken- ing those of the part now affected ? Why does inflammation often arise in parts only sympathetically affected, and consequently far removed from the offending cause ? Why is inflammation often as apt to spread to neighbouring parts, between which and the part first affected, there is no direct communication of vessels, as to parts in continuation with that part? “ These phenomena, it is evident, (says Dr. Philip) are referrible to the agency of the nervous system, and seem readily ex- plained by the experiments, vhich prove, that the effects of both stimuli and sedatives, acting through this system, are felt by the vessels, and that independently of the inter- vention of any effect produced on the heart INFLAMMATION. (Exp. 27, 28.) Thus, the irritation of the nerves of the inflamed part may excite the larger arteries of this part, or of distant parts, •r of the whole sanguiferous system. It will of course be most apt to do so, where the irritation excit^l by the inflammation is greatest and, consequently in the more im- portant vital parts. It cannot appear surpri- sing, that inflammation should suddenly cease in one part and attack another, when we know, that the nerves are capable of exciting to due action the capillaries of the one part, and in the other of impairing the vigour of those, which have not suffered. In the same way, we account for parts only sympathetically affected becoming inflamed, and for inflammation readily spreading to neighbouring parts, which always sympa- thize, although there is no direct communi- cation between them, either of vessels or nerves. - ’ (On the Vital Functions, p. 279, fyc. Ed. 2.) Respecting the inference, made by Dr. Philip from his experiments, that the circu- lation is slower in inflamed, than uninflamed arteries, Dr. J. Thompson conceives, that its truth “ is not necessary to the establish- ment of Mr. Allen’s hypothesis ; and from a number of experiments which I have at different times made upon frogs, I am incli- ned to believe, that a diminished velocity of the blood, in the capillary branches, is by no means a necessary , constant, nor even the most common effect of incipient and moderate degrees of inflammation .” (P. 75.) In order to reconcile this difference in the statements made by the only two writers, who have examined this subject by experi- ment, Dr. Hastings repeated their mode of investigation with the aid of the microscope. His conclusions are, “ that certain stimuli, applied to living parts, produce an increased velocity of the blood’s motion, and a con- traction of the blood-vessels. During this state of excitement, the part affected is so far from giving any thing, like the appear- ances of inflammation, that the size of the vessels is diminished, and the part paler. But, if the stimulus be long continued, or increased in power, the small vessels, which in the natural state admit only of one series of globules, become so dilated, as to allow an accumulation of a much less fluid and redder blood in them, which loses its globular appearance, and moves much more slowly, than that which previously passed through the vessels. The part now appears inflamed. If the stimulus be removed, the vessels do not soon regain their original state ; time is necessary to allow them to recover their contractile power, so as to prevent the impetus, with which the blood is propelled by the hear! and larger arteries from keeping up the dilated state of the ca- pillaries. Here then we are obliged to ad- mit, with Boerhaave, that there is an error loci ; for, a denser and redder blood passes into small vessels, which before carried much more fluid contents ; but the error loci does not cause the inflammation, but results from the previously weakened state of the capilla- ries. In this manner, the blood may occa- sionally be extravasated in inflammation, without any actual rupture of a vessel, for the exhalants may be so weakened, ami dilated, as to allow globules to pass through them. “ If the stimulus, which produces the in- flammation, be of a very acrid nature, de- bility of the vessels is frequently induced without any previous excitement. The blood in all the smaller vessels becomes very red, circulates very slowly, and in some vessels stagnates. u The application of a stimulus, different from that which produced inflammation, w ill sometimes bring on resolution. When (his occurs, the dilated vessels contract; they no longer contain a red, dense homo- geneous fluid, but again receive blood, con- sisting of small, nearly colourless globules, which float in a colourless fluid ; and the motion of these globules at length becomes as quick as before the inflammation took place. If, however, the inflammation pro- ceed, the blood becomes nearly stagnant ; it continues very red, and the vessels are much dilated. £ ‘ When this high degree of inflammation is not relieved, sphacelus ensues. The part then feels softer to the finger, and gives way with less force. The vessels are much dila- ted, the blood does not move, it loses its red colour, and becomes of a yellowdsh brown hue. The separation of the dead from the living part takes place soon after this change in the colour of the blood. “ While the ulceration, produced by this separation of the dead from the living part of the web is healing, the capillary vessels, distributed on the ulcerated surface, and the contiguous parts, are much distended with arterial red blood, which is moved very slowly. When the ulceration is healed, the vessels become contracted, and circulate the fluid, with the same degree of velocity as before the inflammation was excited. i£ With respect to the seat of inflammation, it may be observed, that the capillaries are first affected ; but even the small arteries of the web are also occasionally distended.” ( Hastings on Inflammation of the Mucous Membrane of the Lungs, fyc. p. 90 — 92.) With respect to the doctrine, espoused by some pathologists, that the smaller branches of veins are the exclusive seat of inflamma- tion, the same author observes, that the microscope shows us, that the most minute arterial branches, though far less numerous, are equally affected with weakness and distention. In the course of Dr. Hastings’s inquiry, it is proved, that the healthy circulation of the blood essentially depends upon a due degree of action in the vessels throughout the sys- tem ; that the application of stimuli, while it increases the action of the vessels, produ- ces none of the symptoms of inflammation. When, however, the excessive action of these stimuli has impaired the excitability of the small vessels, the phenomena of inflam- mation are fully manifested ; and when their 118 INFLAMMATION. excitability is restored, the inflnmmation subsides. It may be logically inferred, there- fore. says this writer, that inflammation con- sists in a weakened action of the capillaries , by which the equilibrium between the larger arid smaller vessels is destroyed , and the latter be- come distended. And, with respect to the conclusion, drawn by Dr. Thomson from his experiments, that inflammation, in moderate degrees, consists in an increased action of the vessels. Dr. Hastings argues, that the writer’s belief in the excitement of the capillaries, in some cases of inflammation, arises from his having denominated that a state of inflammation, which ought not to be so called. “ The application of the salt, (says Dr. Thomson) produced an increased velocity in the dilated larger and smaller arteries and capillary vessels, to which it was more immediately applied. In nine experi- ments, the phenomena of which I have minutely recorded, the application of the salt was not only followed by a bright red colour, visible to the naked eye, and a sensi- ble enlargement of the arterial and venous branches, but with an increased rapidity of circulation in the capillary vessels; the glo- bules becoming less distinct, than before the application of the salt, and obviously less distinct, from the rapidity of their motion, than the globules in the capillary vessels in the uninflamed part of the web in the same animal. The repeated application, however , of the salt to the same vessels, was always sooner or later follo wed by retarded capillary circulation, or even by complete stagnation.” (See Thomson's Lectures, p. 68.) The results of other experiments, made by this gentle- man, and which coincide with the sentiments of Dr. VV. Philips and Dr. Hastings, need riot here be cited. Now, with regard to those experiments, which seemed to Dr. Thomson to justify the inference, that moderate degrees of inflam- mation may be attended with an increased velocity of the ’blood in the inflamed vessels, Dr. Hastings, as I have already said, objects, that the appearances seen, while such velo- city of the circulation presented itself in the vessels affected, ought not to have been denominated inflammation ; because “ it constantly happened in hisown experiments, that when inflammation commenced, no . globules could be seen even in the blood of the affected vessels It was universally con verted into a bright red homogeneous fluid. So that globules could never be seen in the capillaries of a really inflame d part, much less moving with great velocity. He argues, that the state, alluded lo by Dr. Thomson, is only that temporary excitement of the capillaries, generally preceding their debility, which is inseparable from inflammation. (See Hast- ings on lnfla mmnlon fyc p. 98, 1**1.) Of course, such writers as believe, that the blood in the capillaries is not propelled by these vessels themselves, but by the impulse received from the heart, cannot assent to the foregoing view, in which the proximate cause of the inflammation is ascribed to de- bility of those vessels. Dr. Parry argues, that the theory, which represents this pr»>, It'S.) With respect to I he butty coat of the blood, Dr. Thomson stales, that it is not by the buffy coat alone, hut by the butty coat, in conjunction with the quantity and firmness of the coagulum, that v\e must judge of the propriety of any further detraction. When the buffy coat has a firm and tenacious con- sistence, and when the pain continues una- bated, we may conclude, that the inflamma- tion is not subdued. But, when the c lagulum is soft and easily broken and when the colour of the buffy coat is changed from a yellowish to a greenish hu ■, Dr. Thomson thinks, that little or no benefit can be derived from bleeding. Efut - as already mentioned, every practitioner should remember, that, in particular constitutions, and in pregnancy, the blood lakeri away naturally exhibits a butty appearance, independently of inflammation. The preceding remarks chiefly relate to general bleeding ; for, in phlegmonous inflam- mation. topical bleeding is scarcely ever improper. It is always a point highly worthy of the surgeon’s consideration, whether bleeding in or near the part will answer bet- ter, than taking the blood from the general habit ; for, certainly less may be removed in this w ay, so as to have equal effect upon the part inflamed, and probably, upon every other disease that is relieved by bleeding, with less injury to (he constitution. Although, in many case-., ihe general habit is relieved by bleeding, yet it is the part affected which most requires this evacuation. That local bleeding lias very considerable effects on the inflamed part, is proved by the sudden relief u hich is often produced by the application of leeches in cases of gout The mere use of leeches, without other measures, will also sometimes remove a tumour in the breast, having all the appearances of a scirrhus, which cannot be considered as inflammatory, so that topical bleeding extends its power further, than the mere checking of inflam- mation. Some part of its effect has been imputed to sympathy. (Hunter.) There are three modes of performing topical bleed- ing : by cupping; by leeches; and by dividing or scarifying the dilated vesse|> leading to the inflamed part. (See Bleeding.) Upon the head and face, leeches are commonly em- ployed ; upon the chest, either leeches or cupping; upon the abdomen, leeches; and upon the joints, either cupping or leeches. When the eye is inflamed, leeches may either be applied to the adjoini g temple ; or the dilated vessels of the conjunctiva may be scarified ; or both methods may be adopt- ed. When the inflammation extends quite to the surface of the body, leeches are always most eligible, as their bites cause less irritation in inflamed parts, than the punctures of the scarificator, or the pressure of cupping glasses. Purging. The exhibition of mild laxative medicines, and saline purgatives, isa principal means of diminishing inflammation. Purging does not produce such lasting weakness as is the consequence of bleeding, and, therefore, it is scarcely ever omitted, even when the abstraction of blood is deeme l improper. Saline purges must lessen the quantity of circulating blood, inasmuch as they increase the secretion from the intestinal arteries ; and therefore, t hey probably operate beneficially in the cure of local inflammation, much upon the same principle as bleeding. Mr. Hunter was of opinion, that purging lowers action, without diminishing strength, by which we are probably to understand, without produ- cing a very lasting or permanent loss of strength. With respect to mild laxative me- dicines, none are superior to manna, rhubarb, oleum m ini, and the like ; and of the saline purgatives, the best are, the sulphate of soda, tartrate of potass, phosphate of soda, and sulphate of magnesia. It may here be re- marked, that, besides the benefit, which the local i ii II munition derives from the judicious administration of purgatives, the costiveness and heat, which usually attend the syropto- INFLAMMATION. 123 uiatic fever, sue also removed by the same means. “ Purgatives (says Dr. Thomson) are more or less required in almost every species of inflammation ; but they are more peculiar- ly necessary in those, which are accompa- nied with a high degree of fever, or with derangement of the digestive, or biliary or- gans In cases of inflammation, which have a tendency to spontaneous resolution, they are almost always the best, and often the only remedies that are required.” ( Lectures on Inflammation, p 171 ) Considering the general approbation of the employment of mild saline purgatives in cases of inflammation, I confess that 1 was not a little surprised to find merely the fol- lowing short unfavourable notice taken of them by a celebrated foreign professor, in his account of the treatment of inflamma- tion. “ As for purgatives, they must be used with discretion. There are none of them antiphlogistic, as has been pretended. They always produce more or less irritation, and can only be applicable, when the cause of the inflammation is in the intestinal ca- nal. In the beginning of the complaint we ought, therefore, in general to abstai from them, and confine ourselves to emollient clysters ” ( Boyer , Trail6 des Maladies Chi- rurgicales , T. 1, p. 39.) Diaphoretic and nauseating Medicines. Medicines, which have the power of pro- ducing sickness, lessen, fora time, the ac- tion, and even the general powers of life. This is in consequence of every part of the body sympathizing with the stomach ; and the effect may be very quickly excited Sickness lowers the pulse, makes the small vessels contract, and rather disposes the skin to perspiration But, nothing more than nausea should be caused ; for vomiting "rather rouses than depresses. ( Hunter ) Nauseating medicines, employed after bleeding has been practised once or twice, are often productive of considerable bene- fit ; but there are some affections, in which they cannot be used, such as inflammation of the stomach and intestines. In all super- ficial inflammations, however, they may be safely and advantageously exhibited, as well as in most inflammatory affections in- ternally situated. In inflammation of the dura mater and brain, and, indeed, iri every instance, in whieh there is an urgent reason for putting as sudden a check as possible to the continuance of the affection, the em- ployment of nauseating doses of antimony is most strongly indicated. The tarlrite of antimony (emetic tartar) is the medicine, on W T hich practitioners place the greatest reli- ance, and it is to be prescribed for the pur- pose of exciting nausea, as follows: — 1^. Antimonii tartarisati grana duo ; Aquae dis- tillatae uncias quatuor. Misce et cola. Do- sis, Uneia dimidia sexta quaque horf cold, and, in particular, bv continually abstracting the heat evolved in the part, by keeping up a constant evaporation from its surface. « Of the local remedies, applied directly to inflamed parts (says Dr. Thomson) cold is undoubtedly one of the most powerful. In reducing the temperature, cold dimi- nishes the morbid sensibility and pain ot in- flamed parts; and, probably, in consequence of this, the action also of the vessels, by which the inflamed parts are supplied with blood. The most common mode ot em- ploying cold is by the application to the part inflamed of cloths, which have been dipped in cold water. These are to be repeat- ed as often as they become warm, or any relief is experienced by the patient from their use. When the inflammation is seat- ed on the remote parts of either the upper or lower extremities ot the body, the in- flamed part itself may he immersed in wa- ter. This immersion, as I shall afterward have occasion to mention, has often been found useful in superficial burns. In 1)1 ” r . 1 to increase the effect produced l»v cold, it IN-FLA MM \TFQN, 327 lias been proposed to reduce the tempera- ture of the water below that of the surround- ing atmosphere, by a proper mixture of sa- line bodies, as some of these are known to produce cold during their solution in water, or even in very urgent cases to apply ice or snow. The ice, however, must not be ap- plied too long, nor in too large a quantity ; for, it very quickly reduces the temperature of the part to which it is applied, and, in some instances, has been known to occa- sion gangrene, &c. (On Inflammation, p. 180 .) With the cold water applied to phlegmo- nous intiammation, it is usual to blend some remedies which are astringent, and suppo- sed to nave also a sedative quality. Theace- tite of h ad, sulphate of zinc, and vinegar, seem now, indeed, to have acquired p> rma- nent celebrity for their efficacy in resolving intiammation. Extensive experience, and long-establish- ed trials, have now fully confirmed the vir- tue of all those local remedies, in which the acetite of lead is the active ingredient. M. Goulard, and other French surgeons, found, that the objections to the employment of many other sedative applications in the treatment of inflammation, did not exist against the use of this preparation of lead The universal assent of modern practitioners proves, indeed, that the acetite of lead as a local application for genuine phlegmonous inflammation, is certainly unsurpassed, if not unrivalled, in point of efficacy. The preparations of lead are recommend- ed by M. Goulard, as almost equally applica- ble to every stage of inflammation. When swellings have fully suppurated, the employ- ment, of what he calls, the extractum Satur- ni, will almost always render it unnecessary to open them. Even in gangrene, the solu- tion of lead is represented by this zealous writer, as a remedy deserving of the greatest confidence. But, notwithstanding the above exaggera- tion, every man of experience and observa- tion will allow, that, while there is a chance of accomplishing resolution, no local appli- cations to phlegmonous inflammation are in general so proper as cold lotions, containing the acetite of lead. “ The manner in which it operates in curing inflammation (as Dr. Thomson ob- serves) is not known to us, nor is it at all times easy to distinguish between the share, which the lead has in allaying inflammation, and that which is to be attributed to the coldness of the water in which it is dissolved. No one, however, will doubt of the efficacy of this remedy, who has ever felt it in his own body, or witnessed in others the sooth- ing and agreeable effects, which it produces in excoriations cf the skin, or in inflamma- tion of mucous membranes. Lead is a remedy, which is often highly useful in excoriations from friction, in punctured wounds with inflammation of absorbent vessels, veins, nerves, &c. in slight burns, in cutaneous heat, eruptions ot the face, in frac- tures and dislocations, in the inflammation attending scirrhus and cancer, syphilis and gonorrhoea, in wounds accompanied w it'a excoriation from the discharges they emit, and in wounds attended with a burning sensation of pain.” (P. 182.) F rom the poisonous qualities of lead, when taken into the system, and from the possi- bility of this mineral being absorbed from the surface of the body, objections have arisen against the free use of its preparations, even as outv\ard remedies in cases of inflam- mation. Certain it is, however, that though the possibility of such absorption is proved by the occurrence of the disorder called the colica pictonum, which originates in painters from the white lead absorbed into the sys- tem, yet, any ill effects from the use of lead, as an application io inflamed parts, are so exceedingly rare, that they can hardly form a serious objection to the practice, ft is a fact, that, in inflamed parts, there is an im- pediment to absorption, and this circum- stance may tend to render the employ ment of lead a matter of safety. Mr. B Bell ob- serves, that in all the experience which he had had of the external application of lead and its preparations, and in many cases, par- ticularly of burns, where he had known the greatest part of the surface of the body covered with applications of this description for days, nay, for weeks together, he did not recollect a single instance of any disa- greeable symptom being ever produced by them. Nor has Dr. Thomson ever seen the colica pictonum follow the use of Goulard. (See Lectures on Inflammation, p . 183.) A lotion composed of acetite of lead, vine- gar, and water, is very commonly employed. Plumbi Acetatis jjss. Solve in Acet. pur. j|iv. Et adde Aq. Fontanae distill. Ifoij. The vinegar makes the solution more complete. In all common cases, a teaspoonful of the liquor plumbi acetatis, blended with a pint of water, will be found an eligible lotion. Occasionally, bread-crumb is moistened in the fluid, and applied in the form of a poul- tice ; but linen dipped in the lotion, and kept constantly wet with it, is mostly pre- ferred. Thus a continual evaporation is maintained, and of course a regular abitrac- tion of heat. When the surgeon is afraid of employing a solution of lead, he may try one of the sulphate of zinc. One dram of this sub- stance is to be dissolved in a pint of wa- ter, and linen, well wet with the lotion, is to be applied to the inflamed part. Many practitioners impute very little real efficacy either to the acetite of lead, or sul- phate of zinc, contained in the above ap- plications : and they attribute all the good that is produced, entirely to the evaporation kept up from the surface of the inflamed part, and to the cotdnessof the fluid in which the metallic salts are dissolved. Surgeons, who entertain these sentiments, think the application of simple cold water quite as efficacious as that of any medicated lotions. There are particular cases of inflammation, in which the extravasation of blood and lymph, in the interstices of the inflamed INFLAMMATION. m part, is exceedingly copious, and the swell- ing considerable, but the pain and redness not particularly great. In such instances, it is an indication to rouse the action of the ab- sorbents, in order that those vessels may re- in >ve the extravasated fluid, and with this V; mv, a more powerf d discuiieut lotion may be employed than in other cases, and some- times, it is even better to use embrocations and linimen s, than any sort of lotion. The following discutient lotions are often em- ployed : Ammonite Muriataj ,^ss. 'ceti , Spiriths Vini rectificati ; sing ft>j. M. p*. Liq. Ammon. Acet. Spir. Vini rectil. ;• Aq. Distillatai ; sing. §iv. M. The Liq. Ammo-, nia? Acet. also alone answers very well. When the part affect- d with inflammation is not very tender, or when it lies deep, ap- plications of the vegetable acid are often had recourse to with considerable advan- tage ; and the most effectual form of using it seems to be a poultice made with vinegar and crumb of bread. In such cases, it lias been thought, that an alternate use of this remedy, and the saturnine lo. ion, has produ- ced more beneficial effects, than are com- monly observed from a continued use of one of them. (B. Bell.) However, surgeons of the present day see to think, that vinegar can be as advantageously applied in the form ot a lotion, as in that of a poultice, and, certainly, with less trouble. Alcohol and aither Have acquired some celebrity as local remedies for inflammation. No doubt one great reason why they are not more extensively used for this purpose is, the expense attending such treatment, as these fluids evaporate with great rapidity. Alcohol may possibly prove useful from its astringent qualities ; but it seems uch more rational to impute both its virtue, and that aether, to the powerful manner, in which their evaporation deprives the infla- med nart of its heat. Warm Applications. The absurdity of at- tempting to reconcile every usef-d practice \vl . a philosophical theory, is, in no in- stance, morestri; igly exemplified, than in the opposite sorts of local applications, which are of service in inflammation. The g «erality of cases undoubtedly receive most l* ief from the use of cold sedative astringent lotions : butthere are constitutionsaud parts, which derive most service from the local employment of wa rn emollient remedies. Were 1 to endeavour to define the particu- lar instances, in which the latter applications avail most, I should take upon me a task, which has baffle-! all the most able surgical writers. The first stage of the acute oph- thalmy, and the hernia humoralis, or infla- med testicle, may be specified, however, as examples, in which, generally speaking, warm emollient applications are better than cold astringent ones. Yet, even with res- pect to inflammation of the testis, there is some difference of opinion about the supe- riority of cold or warm applications. Mr. James’s sentiments are as follows : in the treatment it is of importance to consider the differences of the cause : thus, in mumps and rheumatism, the constitution is chietp, to be attended to, and cold applications are certainly improper. When it (the inflamma- tion of the testis) arises from a blow, after leeches have been freely employed, fomen- t tions are the best remedy But Mr. James thinks, that this is not the rase, in many instances of hernia humoralis trom gonor- rhoea, where cold applications are prefer- able ; but, he owns, that the feelings of the patient will best determine the point. ( James on Inflammation, p 164.) “ Fomentations, or embrocations with warm water, (as a j dicious writer has re- marked! are often a very powerful means of abating internal inflammation. This ef- fect is ve ,- y apparent in some of the deeper seated inflammations, as in the inflammation of the urinary bladder, intestines, or other viscera contained within the cavity of the abdomen. The warmth, in this case, may be applied to the surface of the abdomen, by bath or fomentation, or in the way of injec- tion, by the anus, &c. In some inflamma- tions of the joints, warmth also is found to be very useful. These, however, are in- flammations, which have a tendency to the chronic state. (See Thomsonon Inflammation, p . 188.) If we may judge by the feelings of certain patients, there are undoubtedly particular constitutions, in which the local use ot warm remedies produces greate- relief than that of cold ones This circumstance, however, does not generally happen ; and, as warm emollient applications, of ail kinds, have the most powerful influence in promoting sup- puration, a fact admitted by every experien- ced practitioner, the use of such remedies, while the resolution of inflammation is prac- tical must be highly censurable. But, I am ready to grant, that in all cases of inflammal: o, which manifestly cannot be cured without suppuration, the emollient plan of treatment ought to be at once adopt- ed ; for the sooner the matter is formed, the spoiler the inflammation itself is stopped. The inflammation attending contused and gunshot wounds, and that accompanying bolls and carbuncles, are of this description. The inflammation, originating in fevers, com- monly ends in suppuration, and, in such instances, perhaps, it might he advantageous, also, to employ at once the emollient treat- ment. Warmth and moisture together, in other words fomentations, are commonly had re- course to in cases of inflammation ; but, when the warmth is as much as the sensitive principle can bear, it excites action. Whe- ther it is the action of inflammation, or the action of the contraction of the vessels, is unknown. We see that many patients cannot bear warmth, and, therefore, it might he supposed to increase the action of dilatation, and do harm. But, if the pain should arise from the contraction of the in- flamed vessels, benefit would he the result ; though we must doubt that this change is produced, as making the vessels contract would probably give ease. ( Hunter .) INFLAMMATION. From the preceding observations, we must perceive how vain it is to theorize on this subject which even puzzled the genius and penetration of a Hunter. In addition to what has been already observed, I feel totally incapable of giving any useful practi- cal advice, with respect to those cases, in which warm emollient applications should be used in preference to cold astringent ones. I can, however, with confidence remark- that the surgeon who consults the feelings and comfort of the patient on this point, will seldom commit any serious error. Hence, in all cases, in which the first kind of topical applications seem not to produce the wonted degree of relief, let the second sort be tried. From the opportunity of com- parison, a right judgment may then be easily formed. The poultice made of the powder of lin- seed is so easily prepared, that the old bread and milk poultice is now seldom employed. As much hot water is to be put into a basin, t' as the size of the poultice, requires, and then i the linseed pow r der is to be gradually mixed ‘ with the water, till the mass is of a proper ! consistence. Frequently, a little sweet oil ; is also added to keep the application longer 1 soft and moist. Fomentations are only to be considered as temporary applications, while the emol- lient poultices are the permanent ones. The former are, at most, never used more than three times a day, for the space of about half an hour each time. Two cf the best are the - following: — -{J,. Lini contusi ^j. Chamae- meli 3jij. Aq. Distill, ftjvj. Paulisper coque etcola. Or. Papaverisaibi exsiccati ^iv. Aq. Purae Jfevj Coque usque remaneant }feij. et cola. Some practitioners, however, are incli- ned to think warm w ater alone quite as effi- caciousas the decoctiousof particular herbs. Thus Dr. Thomson observes, “ herbs are now seldom used in the way of fomenta- tion, unless in compliance with ancient custom, or with the prejudices of particular individuals. The discutient power of the warm water may be increased by the addi- tion of various substances, such as vinegar, spirits of wine; saline substances, such as common salt, acetite and muriate of ammo- nia. But, these warm and stimulating em- brocations are used chiefly in the passive, chronic, or more indolent species of inflam- mation/’ (See Lectures on In jl0imaiiou. p. 189 .) By pursuing the treatment recommended above, the resolution of the inflammation will in general begin to take place, either in the course of three or four days, or in a shorter space of time. At all events, it may usually be known before the expiration of this period, how the disorder w^U terminate. If the heat, pain, and other attending symp- toms abate ; and, especially, if the tumour begins to decrease, without the occurrence of any gangrenous appearances ; we may then he almost certain, that, by a continu- ance of the same plan, a total resolution will hi time he effected Vor„ If 12*> On the other hand, when all the different symptoms increase, and particularly when the tumour becomes larger, and softish, at- tended with a more violent throbbing pain, we may conclude, that the case will proceed to suppuration. Hence, an immediate change of treatment is indicated, and such applications, as were proper while resolu- tion seemed practicable, are to he left off, and others substituted. This remark relates to the employment of cold astringent reme- dies, which, when suppuration is inevitable, only do harm, by retarding what cannot i e avoided, and affording no relief of the pain and other symptoms. If the inflammation, however, should already be treated with emollients, no alteration of the topical ap- plications is requisite, in consequence of the inevitability of the formation of matter. Indeed, emollient poultices and fomenta- tions are the chief local means both of pro- moting suppuration, and diminishing the pain, violent throbbing, & c. which always precede this termination of phlegmonous inflammation. But, besides the substitution of warm emollient applications for cold astringent lotions, practitioners have decided, that it is also prudent, as soon as the certainty is manifest, to relinquish the free employment of evacuations, particularly bloot-retting, and to allow the patient a more generous .diet. When tin* system is too much redu- ced by the injudicious continuance of rigo- rous antiphlogistic treatment, the progiv s of the ensuing suppuration is always retard- ed in a disadvantageous manner, and the patient is rendered too weak to support ei- ther a Ion .. -tout iriued, or ajprofuse discharge, which it may not he possible to avoid. I shall conclude this article with briefly noticing blisters, rubefacients, issues, and synapisms, as means often employed for the relief of particular cases of inflammation. “Blisters (says Dr. Thomson) are never applied to a part which is actually inflamed. They seem to he chiefly useful by exciting inflammation in a contiguous part. It is from this tendency, which blisters have to produce inflammation, and of course a cer- tain degree of fever, that they are seldom to be employed in acute inflammatory cases, till the constitutional symptoms are by other means in some measure subdued.” — (P. 187 .) “ Of the same nature, though milder in their operation, than blisters, are the whole class of rubefacients. They produce a de- tennination"of blood to the parts to which they are applied, and in a manner not yet well understood, occasion a diminution in the action of the vessels, and consequently in the quantity of blood with which the in; flamed parts, are supplied. This influence is exerted more or less directly in different instances. The extremities of the intercos tal arteries may open both on the pleura lining the chest, and on the surface of the skin covering it, and whatever excites au increased flow of blood into one of these, textures, may be conceived to be attended 17 INF 1N0 13# with a proportionally diminished flow into the other texture, B it, blisters are found by experience to be efficacious in removing inflammation, where no communication whatever can be traced between the blood- vessels of t e inflamed part, and that to which the blister is applied. We have ex- amples of this mode of action in the bene- ficial effects obtained from the application of blisters in inflammation of the brain and the membranes immediately covering it, of the lungs and intestines, or of any of the viscera contained in the cavity of tiie abdo- men. The nearer in such instances the blister or rubefacient can be applied to tiie part inflamed, the greater is the relief ob- tained ; and in general, l believe, it may be laid down as a rule, that the relief, which they afford, will be proportional to the de- gree of inflammation which they excite.” (See Thomson on Inflammation , p. 187, 189.) Synapisms, blisters, and issues are in ma- ny instances applied to situations, which are so remote from and unconnected by v essels with the inflamed parts, that it is impossible to explain their mode of operation except through the medium of the nervous system. 11 The irritation of a synapism applied to the foot (says Dr. Thomson) may relieve an at- tack of gout in the head, or stomach. Bath- ing the feet and legs gives relief in inflam- mation of the bowels ; and the application of a blister, or caustic to the neck, may cure an inflammation of the eyes, &.c. ( P . 1«9.) Here counter irritation is the principle by which an explanation is usually attempted. (See Blisters.) Van Swieten's Commentaries on Boerhaave; Gorler's Compendium Medici mu, 4 to. Lu^d. 1731 ; and Chirurgia Repur gala, 4lo. Lugd. 1742. Vacca., Liber dt Inflammalionis mor- bosa , quae in humano corpore Jit, natures . cau- sis, effectibus, et curalione, 1765. D Mage- nisie,the Doctrine of Inflammations, founded upon reason and experience; and entirely cleared from the contradictory systems of Boer- haave, Van Swieten, and others, 8 vo. t.ond. 1768. Cullen’s First Lines of the Practice of Physic, Vol. 1. John Hunter, on the Blood, Inflammation, §’C. 4to. London, 179 I. Burns's Dissertations. 8vo Glasgow, lbOo. Thom- son’s Lectures on Inflammation, Edinb. 1813. Boyer, Trait 6 des Maladies Chir. T. 1. Del- pech, Precis Elrn. des Alai. Chir. T. 1 ,chap. 1, Paris, 1816. John Herdmnn, Hiss on White Swelling, and the Doctrine of Inflam- mation, 8 vo. Edinb. 1802. F. J. V Brous- sais Hist, des Phlegmasies ou Inflammations Chroniques,&fC. 2 Tom. 8vo. Paris, 1808. C. Wenzel, fiber die Induration und das Gesch- wiir in indurioten Theilen, 8 vo Mainz. 1815, Wilson Philip, on Febrile Diseases, Part 2. Introduction, Ed. 3 ; and Bn Expe- rimental Inquiry into the Laws of the Vital Functions, Ed. 2. 8 vo. Loud. 1818. Caleb H. Parry , Elements of Pathology and The- rapeutics, 8vo. Loud. 1815. Also, Bn Expe- rimental Inquiry into the Nature, fyc. of the Arterial Pulse, 8vo. Land. 1816. Charles H. Parry, Additional Experiments on the Arteries of Warm-blooded Animals, tyc. 8 vo. Loud. 1819. James Wilson, Lectures on the Blood , and on the Anatomy, Physiology, and Surgi- cal Pathology of the l ascular System, 8 vo. Lond. 1819. C. II. Ronnefeld, Animadver- siones nonnullce ad Doctrinam de Infiamma- tione,4lo Lips. I S 1 7 . C. Hastings, a Trea- tise on Inflammation of the Mucou Membrane of the Lungs, particular Nature and Treatment of the different Species of In flam - ma, ion, 8 vo. Lond. Jb21. This work, and those of Mr. J. Hunter, Mr. Wilson, Mr J. Burns, Drs. Parry, Philip and Hostings, de- serve attentive perusal by every body desirous of forming a correct judgment of the nature of inflammation. INJECTION. A fluid intended to be thrown against, or into a part of the body by means of a syringe. Thus port wine and water form an injection, which is used by surgeons for radically curing the hydrocele, and, for this purpose, it is introduced into the cavity of tiie tunica vaginalis, where it excites the degree of inflammation necessa- ry to produce an universal adhesion between this membrane and the albuginea. Thus many fluid remedies are introduced int> the urethra and vagina for the cure of gonorrhoea. In the article Gonorrhoea , will be found an account of the best injections employed for its relief. A few additional remedies of this class are here subjoined. liNJECTIO ACIDI MURIATIC!. R. Aquee distil ^iv. Acid. Mur. gutt. viij. Misce. Useful when the scalding is a very troublesome symptom. lAJECTlO ALUMIiNIS. — Alum 3j. Aq. pur.Jjvj. Misce. — Successtully employed by Dr. Cheston, as an injection in affections of the rectum, either when the internal coat is simply relaxed, and disposed to prolapsus, or when it is studded with loose fungated tumours. In such cases, camphor is also of service. The quantity of alum raaj be in- creased, if the parts will bear it. 1NJECTIO CUPRI AMMONIATI. R. Liquoris Cupri ammon. gutt. xx. Aquas rosae ^iv. Misce. Strongly recommended by Mr. Foot. liNJECTIO QUERCUS. R. Deeocti quer- cus fbj Aluminis purificat. |ss. Misce. May be used, when the lectum, or vagina, i£ disposed to prolapsus from relaxation, or in cases ot gleet. * i.NNOMlNATA ARTER1A. By refer- ing to the article Aneurism, in the Appendix, will be seen the case at full length, in which professor Mott of this city tied the Arteria Innominata for the purpose of directing the blood from an aneurism of the subclavian artery ; together with some remarks upon the criticisms which have appeared against it. Am Ed INOSCULATION denotes, in the lan- guage of anatomy and surgery the union of vessels by conjunction of their extremi- ties. It is generally synonymous with anastomosis , though sometimes a distinction is made, anastomoses signifying the union of vessels by minute ramifications, and inoscu- IiNO I NT 13ll lotion a direct communication by trunks. The great use of inosculations is to facilitate and ensure the continuance of the circula tion, when the large trunks of vessels are obstructed by pressure, disease, &.e. Thus, in cases of aneurism, when the main artery of a limb is tied, the inosculations of the branches, given off above the ligature, with other branches arising below it, form at once a channel, through which the lower part of tne limb is supplied with blood. Were there no such arrangement in the human body as inosculations, aneurisms could never be cured by a surgical opera- tion So infinitely numerous indeed are these inosculations, that they do the office of the subclavian, carotid, and external and internal iliac arteries, when these vessels are tied, and upon this fact is founded the success of some of the most brilliant opera- tions in modern surgery. (See Aneurism.) Even the aorta itself may be perfectly ob- structed, the circulation go on, and every part be fully supplied with blood. (See Aorta.) In dogs, the abdominal aorta has been tied, without the circulation in the hinder extremities being stopped. (See the Experiments of Mr. A. Cooper in Med. C/iir. T'rans. Vol. 2, p. 258;) and the operation, performed a few years ago, in Guv’s hospi- tal, tends to prove that the same thing is possible in the human subject (See Aorta.) From the observations of the same distin- guished surgeon it appears, that the arteries, which form the new circulation in a limb, after the obliteration of the principal artery, are not only enlarged but tortuous. Any great increase, however, in the diameter of the anastomosing vessels is but slowly pro- duced ; for Mr. A. C ooper has injected a limb several weeks after the operation for popliteal aneurism, without being able to force the injection through communicating vessels into the parts below. The limb must have active exercise before the vessels en- large much. On account of the arteries not very readily enlarging, the limbs of per sons who have undergone the operation for aneurism, are for a considerable time weak- er than natural. They feel the influence of cold more, and are more disposed to ulce- rate from slight causes. Hence, the utility of covering them with flannel, or fleecy ho- siery. Hence, the rashness of applying cold washes, bandages, &.c. (See A. Cooper's re- marks in the above-mentioned l ol p 249, et seq) In another place, the same gentleman has published an interesting description of the anastomoses of the arteries of the. groin. Hypothesis (says he) w ould lead to a be- lief, that anastomosing vessels would be numerous in proportion to the lime w hich had elapsed from the operation ; but, the reverse of this is the fact ; for, at first, ma- ny vessels convey the blood, originally conducted by the principal artery 7 . But, gradually, tl^e number of these channels becomes diminished and, after a length of time, a few vessels, conveniently 7 situated for the new circulation, become so much enlarged, as to be capable of conveying an equal portion of blood to that which passed through the original trunk.” The experience of Mr. A. Cooper also tend* to confirm the important fact, that “ it is desirable in femoral aneurism, if not, indeed, in all others, to perform the opera- tion in an early state of the disease,” as the patient then recovers the use of the limb much more quickly, than when the tumour lias been suffered to attain a large size. (See Medico- ( hirurg Trans. Vol. 4, p. 425, et seq.) INTERRUPTED SUTURES. See Su- tures. INTESTINES WOUNDED. See Wounds of the Abdomen. IN fitOSUSCEPTlON. or Intussusception, (from ini us , within and suscipio , to receive.) Called also Volvulus 1* a disease produced by the passing of one portion of an intestine into another, and it U commonly from the upper passing into the lower part. (J. Hun- ter) O this subject. Mr. G. Langstaff lias published an interesting paper, in the Edinb. Surg. Journal. No. XI ; which 1 shall take the liberty of freely quoting. Tub gentleman remarks, (hat the small intestines of children are -so often affected with iutrosusception in a slight degree, that most practitioners must have had opportuni- ties of observing the form of the complaint. The greatest par* of three hundred children who died either of worms, or during denti- tion, at the HAi'ital de la Sabpetriere, and came under the examination of M. Louis, had two, three, four, and even more volvuli, without any inflammation of the parts, or any circumstances leading to a suspicion that these a ft* -ct ions had been injurious during life. 11 These cases (says M. Louis) stem to prove, that inirosusception may be formed, and destroyed again by ihe mere action of the intestines.” (Mnn. de VAcad.de Chirurg. 4/o. Tom. 4. p 22*2.) This opinion is con- firmed by the authority of Dr. Badlie, ( Mor- bid Anatomy, 2 d Edit p. 162 ) w ho observes, that, ‘ i iu opening bodies, particularly of in- fants, an intussusception is not 'infrequently found, which had been attended with rio mischief ; the parts appear perfectly free from inflammation, and they w ould probably have been easily disentangled from each Ollier by their natural peristaltic motion.” The disease, continues Mr. Langstaff, as- sumes a more dangerous, and indeed, gene- rally a fatal form, uh n it occurs at the ter- mination of the small intestines in the cce- cum. A contracted state of ihe part to be introsu cepted, and a dilatation of that por- • ion of the caifal into which this pari must pass, are ssenlial coudii ions to the formation of a volvulus ; and those exist, nowhere so completely as in Ihe situation here alluded to. The extent to which the affection proceeds in this situation, would appear almost incre- dible, if it were not proved by well-authen- ticated facts. A person who considered the natural situation and connexion of the parts, would of course require the strongest evi- dence before he would believe, that ihe iltf- i N TROSU 8 CEPT ION. Vdd mn, cmcutn, ascending and transverse por- tions of the colon, may descend into the sigmoid flexure of the latter intestine ; nay more, that they may pass through the rectum, and 1)0 protruded in the form of a prociden- tia ani. Sueh cases, however, are recorded. (Langstaff, in Edinb. Med. and Surgical Journal, No. XJ.) This gentleman next relates the case of a child three months old, the body of which he inspected after death, and found to con- firm t he truth of the preceding account. The example was particular in their bein in addition to an extensive introsascepti n in the usual way, a smaller invagination in the. opposite direction, like what probably occur- red in the case related by Mi. Spry; Med. and Physical Journal , No. Xf Sir E. Home, (Trans, of a Society for Medical and Chir. Knowledge, Pol. 1.) ;nvntion> anexumple ot a retrograde intrdsuscepUon, in which a worm was found coiled up round the iitrosuscepted part. The disease took place in a boy who IAd swallowed arsenic. If the following mode of accounting for introsusception be just, it will most frequent- ly happen downwards, although there is no reason why it may not take place in a con* • trary direction ; in which case, the chance of a cure will be increased by the natural actions of tne intestinal canal tending to re- place the intestine ; and probably from this circumstance it may oflener occur than com- monly appears. When the introsusception is downwards, it may be called progressive, and when it happens upwards, retrograde. The manner in which it may take place is, by one portion of a loose, intestine being contracted, and the part immediately below relaxed and di- lated ; under which circumstances, it might very readily happen by the contracted por- tion slipping a little Way into that which is dilated, not from any action in either portion of intestine, hut from some additional weight in the gut above. How far the peristaltic motion, by pushing the contents on to the contracted parts, may force these into the relaxed, Mr. Hunter will not determine, but is inclined to suppose that it will not. By this mode of accounting for an acci- dental introsusception, it may take place either upwards or downwards ; but if a con- tinuance or ari increase of it arises from the action of the intestines, it must be when it is downwards, as we actually find to be the case ; yet this does not explain those in which a considerable portion of intestine appears to have been carried into the gut below : to understand these, we must con- sider the different parts which form the in- trosusception. It is made up of three folds of intestine ; the inner, which passes down, and being reflected upwards, forms the se- cond or inverted portion, which being reflect- ed down again, makes the third or contain- ing part, 1 hat is the outermost, which is always in the natural position. (./. Hunter.) The outward fold is the only one which is active, the inverted portion being perfectly passive, and squeezed down by the outer. which inverts more of itself, so that the an- gle of inversion in this case is always at the angle of reflection of the outer into the middle portion or inverted one, while the innermost is drawn in. From this we can readily see how an introsusception, once be- gun, may have any length of gut drawn in. The external portion acting upon tne other folds in the same way as upon any extrane- ous matter- will by its peri-taltic motion urge them further ; and if any extraneous sub- stance is detained in the cavity of the inner portion, that part will become a fixed point for the outer or containing intestine to act upon l bus it will be squeezed on, till at last the mesentery preventing more of the inner- most part from being drawn in, will act as a kind of stay, yet without entirely hindering the inverted outer fold from going still fur- ther. For it ‘being the middle fold that is acted upon by the outer, and this action continuing after the inner portion becomes fixed, the gut is thrown into folds upon it- self; so that a foot in length of intestine shall form an introsusception not more than three inches long. The outer portion of intestine is alone ac- tive in augmenting the disease when once begun ; but if the inner one were capable of equal action in its natural direction, the ef- fect would be the same, that of endeavouring to invert itself, as in a prolapsus ani ; the outer and inner portions, by their action, would tend to draw in more of the gut, while the intermediate part only would, by its action, have a contrary tendency. The action of the abdominal muscles can- not assist in either forming or continuing this disease, as it must compress equally both above and below, although it is capable of producing the prolapsus ani. When an introsusception begins at the valve of the colon, and inverts that intestine, we find the ileum is not at all affected; which proves that the mesentery, by acting as a slay, prevents its inversion. ( J . Hun- ter.) From the natural attachment of the me- sentery to the intestines, one would, ul the first view of the subject, conceive it impos- sible for any one portion of gut to get far within another; as the greater extent of me- sentery that is carried in along with it would render its further entrance more and more difficult, and we should expect this difficulty to be greater in the large intestines than in the small, as being more closely confined to their situation ; yet one of t he largest intro- susceptions of any known was in the colon, as related by Mr. Whateley. ( Vid . Phil. Trans. Vol. 70, p. 305.) The introsusception appeared to have be- gun at the insertion of the ileum into the colon, and to have carried in the cuecum with ils appendix. The ileum passed on into the colon, till the whole of tin; ascend- ing colon, the transverse arch, and descend- ing colon, were carried into the sigmoid flexure and rectum. The valv^of the colon being the leading part, is at last got as low as the anus; and when the person went to INTROSUSCEPTION m stool ho only emptied the ileum, for one fore advises giving- vomits, with a view to half of the large intestines being filled up by invert the peristaltic motion of the contain the other, the ileum alone, which passed through the centre, discharged its contents. (J. Hunter.) Two questions of considerable importance present themselves to the mind in consider- ing this subject; whether there are any symptoms by which the existence ot the af- fection can he ascertained during life ? And whether we possess any means of relieving it, supposing that its existence could he dis- covered ? The symp.oms attending an intro- susception are common to inflammation of the intestines, hernia, and obstruction of the canal, from whatever cause, and a volvulus is the least frequent cause of such symptoms. (Langstaff.) In the case published by this gentleman, md in those related by Mr. Hun- ter and Mr. Spry, the seat of *he disease was clearly denoted by a hard tumour on the left side of the abdomen. This circumstance, together with the impossibility of throwing, up more than a very small quantity of fluid in cly-ters, ( Hevin , Spry, Langstaff,) and the presence of the other symptoms, would lead us to suspect the nature of the disorder. If £he invaginated portion descended so low as to protrude through the anus, and we could ascertain that it was not an inversion of the gut, the case might be considered as clear, and we should have no hesitation in deliver- ing a prognosis, which, by preparing the friends for the fatal termination, would exo- nerate us from ail blame on its occurrence. ( Langstaff .) In tfie treatment of this disease, bleeding, to lessen the inflammation that might* be brought on, and quicksilver to remove the cause, have been recommended. Quicksilver would have little effect eitherin one way or the other, if the introsuscep ion were downward ; for it is to be supposed that it would easily make its way through t lie innermost contained gut, and, it it should be stopped in its passage, it would by increas- ing its size, become a cause (as before oh-, served) of assisting the disease. In cases of the retrograde kind, quicksilver, assisted, by the peristaltic motion, might be expected :o press the introsusception back ; but even under such circumstances it might get be- tween the containing and inverted gut into the angle of reflection, and by pushing it further on, increase the disease it is intended to cure. {J. Hunter.) Every thing that can increase the action of the intestine downwards, is to be particu- larly avoided, as tending to increase the peri- staltic motion of the outer containing gut, and thus to continue the disease. Medicines can never come into contact with the outer fold, and having passed the inner, can only act on the outer further down, and therefore cannot immediately affect that portion of the outer which contains the introsusception ; but we must suppose that whatever affects or comes into contact with the larger portion of the Canal, sU as to throw it into action, will a !$<> affect by sympathy any part that may escape such application. Mr, Hunter there- ing gut, which will have a tendency to bring the intestines into their natural situation. If this practice should not succeed, it might be proper to consider it as a retrograde intro- susception, and by administering purges endeavour to increase the peristaltic motion downwards. (J. Hunter.) I cannot agree with Mr. Langstaff. that it is to be regretted, Hunter’s name should be affixed to the preceding proposal, or that it is an absurd one ; for purgatives and emetics were only recommended to increase the peristaltic action, tin* former downward, the latter upward, according as the supposed nature of the case might require, and this affect they certainly would have, notwith- standing vomiting is an early and constant symptom of the disease, and an insuperable constipation an equally invariable attendant. The method I allow, however, is not very hopeful, and may sometimes be frustrated by the formation of adhesions. According to Mr. Langstaff, the Recherch- s Historiq'ues sur la Gas'rotomie dans le cas de Volvulus, par M. H via, {Mem. de VAcad. de Chirurgie , Tom. 4, 4 to.) contain many interesting facts and sound reasoning. There we find a very ample discussion of the question, concerning the propriety ot opening the abdomen, in order to disentangle the introsuscepted intes- tine ; a proposal which M. Hevin very pro- perly condemns. If the equivocal and uncertain nature of the symptoms of volvulus were not suffi- cient to deter us from undertaking an opera* tion, which, under the most favourable cir- cumstances, could not fail to be extremely difficult, and imminently hazardous to the patient, the state of the invaginated parts would entirely banish all thoughts of such an imprudent attempt ; for the different folds of the intestine often become ag- glutinated to each other, so that they can hardly be withdrawn after death ; ( Simpson , Edinburgh Med. Essays, Vol. 6, Hevin' s 4th Obs. Malcolm, Physical and Lit. Essays, Vol. 2, p. 360. Hunter, Med. and Chir. Trans, and Soemmering in Transl. of Bail lie’s Morb. Anat.) Nay, the stricture on the introsus cepted part may cause it to inflame, and even mortify. ( Soemmering .) It is very clear that, in this state of parts, the opera- tion of gastrotomy w r ould be totally inad- missible, even if the symptoms could clearly indicate the nature of the case, and the affected part could be easily reached and examined. (Langst ff ) The forcible injection of clysters was found useless by Dr. Monro, and the agglu- tination of the parts must produce an insu- perable obstacle to the bowels being pushed back by this means. {Langstaff.) Some have proposed the employment of a long bougie, or a piece of whalebone, to push back the intestine : and this proposal may be adopted, when we are furnished with an instrument, adapted to follow the windings of the large .intestine to its origin in the 134 INI mi right ilium, without any risk of perforating the gut in its course. ( Langst ff.) it must be confessed, that both surgery and medicine are almost totally unavailing in the present disease. Yet, here, as in many other instances, the resources of nature are exhibited in a most wonderful and astonish- ing manner, while those of art completely fail The invaginated portion of intestine sometimes sloughs, and is discharged per anum while the agglutination of the parts preserves the continuity of the intestinal canal. The nnals of medicine furnish nume- rous instances, in which long pieces of gut have been discharged in this manner, and the patient has recovered. Hence, some hope may he allowed under the most un- promising circumstances. In a case, related in Duncan’s Commentaries, eighteen inches of small intestine were voided per anum , Vol. 9 p. 278. Three similar instances oc- cur in M. Hevin’s Memoir ; twenty-three in- ches of colon came away in one of these, and twenty-eight of small intestines in another. Other cases occur in the Physical and Litera- ry Essays, Yol. 2, p. 361 ; in Duncan’s Annals, Vol. 6 p. 298 ; in the Medical and Chirurgical Transactions, Vol. 2; where Dr Baillie states, that a yard of intestine was voided. The patients did not, however, ultimately survive in every one of these instances. (Lang staff in Edinb. Med. and Surgical Jour- nal.) Langenbeck has recorded an instance, in which a prolapsus of the large intestines protruded half an ell out of the anus. The disease had lasted thirty weeks. Langen- beck made an incision into, or rather through, the protruded inverted bowel, immediately below the sphincter ani. He first divided the inner vascular coat, then the muscular, and lastly the outer coat with great caution. He now discovered, within the protruded inverted bowel, w T hich he had opened, ano- ther part of the intestinal canal, which was not yet inverted. He remarked upon it the ap- pendices epiploicae, and the w hite shining peritonajal coat. This last portion would also have become inverted, had the disease continued. He next reduced the latter uu- inverted part, and afterward succeeded in replacing the rest, of the protrusion; which did not fall dowm again w hen the boy had stools. No bad symptoms immediately fol- lowed ; but, the lad being very weak, survi- ved only eight days (See Bibl fur die Chir. B. 3 p. 756, Gult. 1811.) Hecin in Mem. de V Acad, de Chir. Hunter's Observations, in the Trans, of a Society for the Improvement of Medical and Chirurgical Know l dge, l ol. I , p. 103, el seq V Encyclo- pedic Methodique, Partie Chir. Art. Gastro- tomie. A. Voter, De Invaginatione Inieslinor- um; ( Halier Disp. Anal. 1, 481. > C. // Velse. De Mut>ii> Intestinorum Ingrcssu, &,-c. Lugd 1742. ( Haller, Disp. Anal 7 97.) J. C. Lettsom, The History of an Extraordinary Intussusception, wi h an account of the dissection by Mr. T. IVhael- ly, 4 to. Lonl. 1786. And Laigstaff's Re- marksinthe Edinb. Med. and Surgical Journal, J Vo. XL INVERSION OF THE UTERUS. See Uterus , Inversion of IRIS, PROLAPSUS OF. As long as the humours, which fill the cavity of the eye, and in which the iris is immersed and sus- pended, remain in perfect equilibrium with respect to each other, that membrane retains its natural position, and a suitable- distance from the cornea, and although of a very de- licate and yielding texture, it contracts, and relaxes itself, without ever forming any ir- regular fold. But, when the aqueous hu- mour has escaped through an accidental, or artificial, opening in the cornea, the iris is pressed forward by the humours situated be- hind it, and is urged gradually towards the cornea until a portion of it protrudes from the eye, at the same opening, through which the aqueous humour made its escape. Thus a small turner of the same colour as the iris forms on the cornea, sometimes named staphyloma of the iris ; sometimes procidentia, or prolapsus of the iris. The causes of this complaint are such wounds and ulcers of the cornea, as make an opening of a certain extent into the an- terior chamber of the aqueous humour, and such violent contusions of the eyeball, as occasion a rupture of the cornea. If the edges of a wound in this situation, whether accidental, made for the purpose of extract- ing the cataract, or evacuating the matter of hypopium, be not brought immediately af- terward into reciprocal contact, or continue not sufficiently agglutinated together to pre- vent the escape of the aqueous humour from the anterior chamber, regularly as this fluid is reproduced ; the iris, drawn by its conti- nual flux towards the cornea, glides between the lips of the wound, becomes elongated, and a portion of it gradually protrudes be- yond the cornea, in the form of a small tu- mour. The same thing lakes place, whene- verthe eyeball unfortunately receives a blow, nr is too much compressed by bandages, dur- i g the existence of a recent w r ound of the cor- nea. Also, if the patient should be affected, in this circumstance, with a spasm of the muscles of the eye, with violent and repeat- ed vomiting, or with strong and frequent coughing, a prolapsus of the iris may be caused. When an ulcer of the cornea pene- trates the anterior chamner of the aqueous humour, the same inconvenience happens more frequently, than when there is a recent wound of that membrane ; for, the solution of continuity in the cornea, arising from an ulcer, is attended with loss of substance, and in a membrane, so tense and com- pact as this is, the edges of an ulcer do not admit of being brought into mutual con- tact. The little tumour is likewise necessarily of the same colour as the iris, viz. brown, or grayish, being surrounded at its base by an opaque circle of the cornea, on which membrane there is an ulcer, or a wound of not a very recent description. As it usually happens, that the cornea is Oidy penetrated at one port of its circumfer- IRIS. 135 ence by a wound, or ulcer, so in practice, only one prolapsus of the iris is commonly met with in the same eye. But if the cor- nea should happen to be wounded, or ul- cerated at several distinct points, the iris may protrude at several different places of the same eye, forming an equal number of small projecting tumours on the surface of the cornea. Scarpa has seen a patient who had three very distinct protrusions ot the iris on the same cornea, m consequence of three separate ulcers penetrating the ante- rior chamber of the aqueous humour; one in the upper, and two in the lower segment of the cornea. If, says Scarpa, the delicate structure of the iris ; the great quantity of blood-vessels, which enter it; and the numerous nervous filaments, which proceed to be distributed to it, as a common centre ; Kfe considered, the nature and severity of those symptoms may be readily accounted for, which are wont to attend this disease, however small the portion of the iris projecting from the cornea may be, even if no larger than a fly’s head. The hard and continu 1 frictions to which this delicate membrane is then ex posed, in consequence of the motions of the eyelids; together with the access of air, tears, and gum to it; are causes quite ade- quate to the production of continual irrita- tion ; and the blood which tends to the point of the greatest irritation, cannot fail to render the projecting portion of the iris much larger, almost directly after its pro- trusion, than it was at the moment of its first passing through the cornea. Hence it becomes, soon after the prolapsus, more incarcerated and irritated, than it was at first. In the incipient state of the com- plaint, the patient complains of a pain, simi- lar to what would arige from a pin penetra- ting the eye ; next he begins to experience, at the same time, an oppressive sensation of tightness, or constriction, over the whole eyeballs. Inflammation of the conjunctiva, and eyelids, a burning effusion of tears, and an absolute inability to endure the light, successively take place As the protruded portion of the iris drags after it all the rest of this membrane, the pupil assumes of me- chanical necessity an oval shape, and devi- ates from the centre of the iris, towards the seat of the prolapsus. The intensity of the pain, produced by the inflammation, and other symptoms attendant on the prolapsus of the iris, does not, however, always con- tinue to increase. Indeed, in practice, cases of old protru- sions of the iris often occur, where, after the disease has been left to itself, the pain and inflammation spontaneously subside, and the tumour of the iris becomes almost completely insensible. Scarpa met with a man, fifty years of age, who had had a pro- lapsus of the iris in the right eye ten weeks ; it was as large as two grains of millet seed ; the patient bore it with the greatest indiffer- ence, and without any other inconvenience, than a little chronic redness of the conjune- tiva, and a difficulty of moving the eyeball freely, in consequence of the friction of the lower eyelid against the tumour formed by the iris. When the extremity of the finger was applied, the little tumour felt hard and callous. In the early stage of ibis disease, some direct the iris to be replaced in its proper situation by means of a wnalebone probe ; and in case of difficulty, to make a ddata- tion of the wound, or ulcer of the cornea, by an incision, proportioned to the exigency of the case, as is done for the return of a strangulated intestinal hernia. Others only recommend stimulating tne prolapsed por- tion of the iris with the view 01 making it contract and shrink into the eye ; or sud- denly exposing the eye affected to a very vivid light, in the beliei, that as tiie pupil then forcibly contracts, the piece of the iris, engaged between the lips of the wound, or ulcer of the cornea, will rise to its proper place. How ever, Scarpa represents all such methods as absolutely useless, and even dangerous. Supposing it were possible, by such attempts, to reduce the iris to its pro- per situation, without tearing or injuring it, still the aqueous humour would escape again through the wound, or ulcer of the cornea, so that the iris, when replaced, would fall down the moment afterward, and project from the cornea in the same way as before the operation. Hence, though Scarpa admits that the prolapsus of the iris is a se- rious accident, he argues that as surgery has no means of suppressing at once, or at least, of suspending the escape of the aqueous hu- mour through a wound, much less through an ulcer of the cornea, when either exceeds certain limits, the prolapsus of the iris, far from being an evil in such unfavourable cir- cumstan- es, is rather useful, and. perhaps, the only means of preventing the total loss of the organ of sight , for the flap of the iris insinuates itself, like a plug, between the edges of the wound, or ulcer of the cornea, and thus completely prevents the exit of the aqueous humour. Here l ought to observe, that Scarpa's unlimited condemnation of the plan oi ever attempting to replace the iris is contrary to the advice delivered by Beer, as may be seen by referring to the article Cataract , where the treatment of the protrusion of the iris after the operation of extraction is noticed. And even with respect to the pro- lapsus of the iris from ulceration making its way through the cornea, Beer distinctly states, that a recent prolapsus of this kind, formed iu the second still existing stu^e of ophtbalmy, may not only be lessened by proper treatment, calculated to produce a quick cicatrization of the ulcer, but the iris may be again completely removed from tne cornea, w ithout any adhesion to the edge ot the ulcer taking place. (B. 2 ) But w'here the prolapsus of the iris remains, as a consequence of previous inflammation of the eye, Beer confesses that it cannot be cured, without a partial adhesion of the iris to the cornea being left, and a dense scar on IRIS. m the latter membrane in the situation of the protruded iris. ( Vol . cit.p. 66.) In conformity to Scarpa’s principles, there are two principal indications in the treat- ment of the recent prolapsus of the iris. The first is, to diminish, as speedily as possible, the exquisite sensibility in the protruded part of the iris ; the other is gradually to destroy the projecting portion of this mem- brane to such a depth, as shall be sufficient to prevent the little tumour from keeping the edges of the wound, or ulcer of the cornea asunder, and retarding cicatrization. The adhesion, however, which connects the iris with the iuside of the a eornea, must not be destroyed For fulfilling these indications, nothing is more effectual, than touching the portion of the iris projecting from the cornea, with the oxygenated muriate of antimony ( butter oj antimony,) or with what is more expeditious and convenient, the argentum nitratum, so as to form an eschar of sufficient depth. And, in order that this operation may be effected with quickness and precision, it is necessary that an assistant, standing behind the patient’s head, should support the upper eyelid with Pellier’s elevator ; and that the patient should keep his eye steadily fixed on one subject. While the assistant gently raises the upper eyelid, the surgeon must depress the lower one, with the index and middle fingers of his left hand ; and with the right, he is to be ready to touch the little prominence formed by the iris, with the argentum nitratum, scraped to a point like a pencil. This is to be applied to the centre of the little tumour, until an eschar of sufficient depth is formed. The pain which the patient experiences at this moment, is very acute ; but, it subsides as soon as the eye is bathed with warm milk. The caustic, in destroying the projecting portion of the iris, destroys the principal organ of sensibility, by covering it with an eschar, of sufficient depth to protect the part affected from the effect of the friction of the eyelids, and from coming into contact with the air and tears. This is the reason, not only why the sense of pricking and con- striction in the eye abates after the applica- tion of the caustic, but also why the inflam- mation of the conjunctiva undergoes a con- siderable diminution, as well as the burning and copious effusion of tears. As in the case of ulcer of the cornea, these advantages only last while the eschar re- mains adherent to the little tumour formed by the iris ; when it falls off, as it usually does two or three days after the use of the caustic, all the above-mentioned symptoms are rekindled, with this difference, that they are less intense and acute, than they were previously, and the tumour of the iris is not so prominent as it was before tbs caustic was applied. When these symptoms make their appearance, the surgeon must once more have recourse to the argentum nitratum, with the precautions explained above ; and he is to employ it a third, and even a fourth time, as occasion may rcqhire, until the prominent portion of the iris is sufficiently reduced to a level with the edges of the wound, or ulcer of the cornea, and no obsta- cle is left to the granulating process, and complete cicatrization. There is a certain period, beyond which the application of caustic to the protruded iris becomes exceedingly dangerous, though at first it may have been highly beneficial : beyond which, the eschar, which previously soot .ed the pain, exasperates it, and repro- duces the inflammation of the conjunctiva in almost as vehement a degree as in the beginning of the disease. This appears to Scarpa to be the case, whenever the sur- geon continues to employ the caustic, after the little tumour of the iris has been destroy- ed to a level with the external edges of the wound, or ulcer of the cornea, and the application begins to destroy the granula- tions just as they are originating. Hence, as soon as tae surgeon perceives, that the part of the iris, projecting from the cornea, is sufficiently lowered, and that the applica- tion of the argentum nitratum, far from allaying, only irritates the disease, he must desist entirely from using the caustic, and be content with introducing between the eye and eyelids, every two hours, the collyrium zinci sulphatis with tlie mucilage of quince- seeds. Every morning and evening, Janin’s ophthalmic ointment, weakened with a double, or triple proportion of lard, is to be applied. If the stimulus of such local reme- dies should not disturb the work of nature, the ulcer gradually diminishes, and heals in the course of a fortnight. The adhesion, which the projecting part of the iris contracts to the internal margin of the wound, or ulcer of the cornea, during the treatment, continues the same after the perfection of the external cicatrix, and of course during the rest of the patient’s life. Hence, even afterthe most successful treat- ment of the prolapsus of the iris, the pupil remains a.liltle inclined toward the place of the scar in the cornea, and of an oval figure. 1 he change in the situation and shape of the pupil, however, cause* little or no diminution of the patient’s faculty of discerning distinct- ly (he smallest objects; and is much less detrimental to the sight, than one, inexpe- rienced in these matters, might conceive ; provided the scar on the cornea be not too extensive, nor situated exactly in the centre of this membrane. In the first case, the sight is the less obstructed, as the pupil, which, on the first occurrence of the pro- lapsus, was narrow, oblong, and drawn considerably toward the wound, or ulcer, gradually enlarges, and forms a less con- tracted oval. As soon as the wound is completely healed, the pupil tends, in some degree, to occupy its former situation in the centre of the cornea ; a fact, also noti- ced by Richter. According to Scarpa, the reeision of the protrusion with scissors can only be practi- sed with success, when the iris has contract- ed a firm adhesion to the internal edge of the wound, or ulcer of the cornea : mu! IRIS. 137 tu ore especially, in that ancient prolapsus of the iris, in which the projecting portion of the iris has become with time almost in- sensible, hard, and callous, with its base strangulated between the edges of the wound, or ulcer of the cornea, and besides being adherent to them, having also a slen- der pedicle. Scarpa indeed has seen an in- carcerated one fall off of itself. In such circumstances, the recision of the old prolapsus of the iris is not attended with the least danger ; for, after removing with a stroke of the scissors, that prominent portion of the iris, which has already contracted Internal adhesions to the ulcerated margin of the cornea, so as to reduce it to a level with the external edges of the ulcer, there is no hazard of renewing the effusion of the aqueous humour, or giving an opportunity for another piece of the irisTo be protruded. One or two applications of the argentum nitratum suffice afterward for the produc- tion of granulations on the ulcer of the cornea, and the formation of a cicatrix. But, it is'not so in the treatment of the recent prolapsus of the iris, which has rlo adhesions to the internal edges of the wound, or ulcer of the cornea. In four subjects recently affected with prolapsus of the iris, after Scarpa had re- moved, with a pair of convex-edged scissors, a portion of that membrane projecting be- yond the cornea, of about the size of a fly’s head, he found, on the ensuing day, that a new portion of the iris, not less than the iirst, had made its way through the ulcer of the cornea, and that the pupil was very much contracted, and drawn considerably further toward the ulcer of the cornea. These circumstances took place, notwithstanding the wound was touched immediately after- ward with the argentym nitratum- Hence Scarpa apprehends, that if he were ever to divide such a little tumour again, it would reappear, and always with an additional protrusion of the iris, and a further distortion of the pupil. The advantage of caustic in the recent sensible prolapsus of the iris ; and the use of scissors only in old callous cases, agree also with the directions given both by Beer and Mr. Travers. ( Lehre von den Augenkr. B. 2. p. 68 ; and Synopsis, p. 280.) There is a particular species of prolapsus, much less frequent, indeed, than that of the iris : but, which does oceur, and, in Scarpa’s opinion, is very improperly termed by mo- dern oculists, “ prolapsus of the tunic of the aqueous humour." ( Janirt , Peltier , Guirin, Gleizc , fyc.) INeither do his sentiments upon this subject agree with those of Beer, whose explanation of the nature of the case is given in Vol. I. of this Dictionary. We shall there see, that it is a case, which he terms ceratocele, and which he thinks arises from a yielding of the inner layers of the cornea, in consequence of the outer ones not having united. And, in his second vol. p. 59, he has given a description of the same kind of disease from the support of the outer layers of the cornea being destroyed by ulceration. This is a point, on which the most hxperien- Vor If '18 ced men differ so much, that it is difficult to reconcile their statements. Dr Vetch seems to have full reliance upon the accuracy of the accounts of a protrusion of the mem- i brane of the aqueous humour. {Treatise on Diseases of the Eye,p. 54, fyc.) Mr. Travers inclines to Beer’s view of the subject, and details reasons for doubting, that the vesicle is a distinct texture : “ its appearance cor- responds accurately to that of the innermost lamella of the cornea.’’ ( Synopsis of the Diseases of the Eye, p. 116.) It is, says Scarpa, a transparent vesicle, filled with an aqueous fluid, and composed of a very delicate membrane, projecting from a wound, or uliper of the cornea, much in the same way as the iris does under- similar circumstances. Scarpa has several times seen this transparent vesicle full of water, elongating itself beyond the cornea, shortly after the operation for the extraction of the cataract, and sometimes, also, in con- sequence of an ulcer of the cornea, espe- cially after rescinding a prolapsed portion of the iris. The generality of oculists believe that tin's little transparent tumour consists of the deli- cate, elastic, diaphanous membrane, which invests the inner surface of the cornea, and is described by Descemet and Demours. u As soon as the membrane lining the cornea (they say) is exposed by the wound, or ulcer of the latter, and the delicate pellicle can no longer resist the impulse of the humours pressing behind it, it is necessitated to yield gradually, to become elongated, and to pro- ject from the wound, or ulcer of the cornea, exactly in the form of a pellucid vesicle.” But, says Scarpa, how remote this theory is from the truth, must be manifest: 1. The delicate and elastic pellicle, described by Descemet and Demours, is not separable by any artifice from the inner surface of the cornea, except near where the cornea and sclerotica unite. Since these protruded vesicles make their appearance in practice at every point of the cornea, and even at its very centre, where Ihe above pellicle is certainly neither separable, nor distinct from the compact texture of the cornea ; it may at least be asserted, that the tunic of the aqueous humour does not in every instance constitute the transparent vesicle in question 2. ft is a well-known fact, that this, vesicular, pellucid prolapsus happens more frequently after fbe extraction of the cataract, than any other occasion. In rhis case, since’ the tunic of the aqueous humour has certainly been divided to afford an exit to the crystalline, no one can be of opinion, that the transpa- rent vesicle, which protrudes from the cornea after this operation, ought to h& attributed to the distention and protrusion of the tunic of the aqueous humour. 3. If, in cases of ulcers of the cornea, the transparent vesicle should sometimes appear after the recision of the prolapsus of the iris, it is obvious, that if it consisted of the tunic of the aqueous humour, it ought invariably to appear before the prolapsus of the iris! 4. Should the surgeon Remove the dfo-truded / IRls. 138 vesicle to a level with the cornea by a stroke of the scissors, a small quantity of limpid water is seen to ooze out, at the moment when the incision is made, without any part of the aqueous humour escaping from the anterior chamber. This inconvenience would be inevitable, were the protruded vesicle in question formed by the delicate elastic pellicle, which is said to invest the inrter surface of the cornea. Besides, the little transparent tumour disappears when the incision is made; but often another one exactly similar to what was cut oft', is found in the very same place the following day. Iiad the little transparent tumour been com- posed of the tunic of the aqueous humour, elongated out of the wound, or ulcer of the cornea, it could not at all events have been reproduced at the same part of the Cornea. Actuated by such reflections, it is clear to Scarpa, that the pretended prolapsus of the tunic of the aqueous humour is not what it is imagined to be ; but strictly speaking, only a forcible protrusion of a portion of the vitreous humour, which, from too much pressure being made on the eye, either at the time of the operation, or afterward, or from a spagm of the muscles of the eye, in- sinuates itself between the edges of the wound after the extraction of the cataract, and projects in the form of a transparent vesicle. The same thing also happens after ulcers of the cornea, whenever the aqueous humour has escaped, and a portion of the vitreous humour is urged by forcible pres- sure towards the ulcer facing the pupil ; or whenever an elongated piece of the vitre- ous humour ; after the recision of a prolap- sed portion of the iris, passes by a shorter route than through the pupil, between the lips of the ulcer of the cornea. At length, we understand, why in both these instances a transparent vesicle forms, even after the recision of the tunic of the aqueous humour, or ulceration of the cornea ; and w r hy it very often reappears in the same place, though it has been cut away to a level with the cor- nea. It is because one or more cells of the vitreous humour, constituting the transpa- rent vesicle, are succeeded after their re- moval by other cells of the same humour, which glide between the lips of the w ound, or ulcer of the cornea, into the same situa- tion. The treatment of this species of prolapsus consists in removing the transparent vesicle, projecting from the wound, or ulcer, by means of a pair of curved scissors with con- vex edges, and bringing the edges of the wound of the cornea immediately afterw ard into perfect apposition, in order that they iHly unite together as exactly as possible. But when there is an ulcer of the cornea, as soon as the vesicle is removed, the sore must be touched with the argentum nitra- tum, so that the eschar may resist any new prolapsus of the vitreous humour, and at the same time dispose the ulcer of the cornea to granulate and heal. If, in some particular cases, the vesicle should pot project sufficiently ftom the wound, or ulcer oi lire cornea, to be inclu- ded in the scissors, the same object may be accomplished by puncturing the tumour with a lancet, or couching-needle ; for when the limpid fluid which it contains is dis- charged, the membrane forming it shrink? within the edges of the wound, or ulcer of the cprnea, and no longer hinders the union of the former, or the cicatrization of the latter. Should the transparent tumour reappear in the same situation, the day after its reci- sion, or puncture, it is right to repeat one of these operations, and to adopt further measures for maintaining the edges of the wound of the cornea in contact ; or if it should be an ulcer, the eschar must be made to adhere more deeply to its bottom and sides, so as toXpnn a greater obstacle to the escape of the vitreous humour. In these circumstanees, the surgeon must take all possible care to obviate such causes as have a tendency to propel the vitreous humour towards the wound, or ulcer of the cornea ; particularly too much pressure on the eye- lids, spasms of the muscles of the eye, cough- ing, sneezing, efforts at stool, and other si- milar ones ; and care must also be taken to check the progress of inflammation. The choroid coat is, likewise not exempt from prolapsus. Scarpa has seen this com plaint in M. Bressanini, an apothecary at Bescape. "A small abscess, formed between the sclerotica and choroid coats, at the dis- tance of two lines from the union of the cornea with the sclerotica, in the inferior hemisphere of the globe of the eye, in con- sequence of a severe internal and external ophthalmy, which had been treated in its incipient stale, with repellent remedies. The abscess burst, and discharged a small quantity of thick viscid lymph ; then a small blackish body, composed of the choroid coat, presented itself on the outside of the little ulcer of the sclerotica. The treatment consisted in applying the argentum nitratum several times to the projecting portion of the choroides, until it w r as consumed, and reduced to a level with the bottom of the ulcer of the cornea. The part then healed. The eye remained, however, considerably weakened, and the pupil afterward became nearly closed. Scarpa sulle Principals Ma- latlie degli Occhi. Venezia , 1802. Richter’s Anfangsgmnde der Wvndarzneykunst, B. 3, Von dtm Vorfalle dcr Regenbogenhaut . Pel- lier, Ohs. sur l'(Eil, p. 350. G. J. Beer, Lehre von den Augcnkrardcheitcn, B. 1, § 402, 518, and 592, and B. 2. § 58, (32, fyc. 8vo. Wien. 1813 — 1817. J. War dr op, Essays on the Morbid Anatomy of the Human Eye , Vol. 2,p.51, 8 vo. Load. 1848. •/. Vetch, A Practi- cal' Treatise on the Diseases of the Eye, p. 53, fyc. Lond. 8 vo. 1820. B. Travers, A Synopsis of the Diseases of the Eye , p. 116, 280, fyc. th'o. Lond. 1820. Weller on J)iseases of the Eye, Transl. by Dr. Monlcaih , 8ro. Glasgow, 1821. For a description of the manner of divid- ing the iris, order to make *rn rMl'ifin.-d pupil, when the natural one is closed, rel’er to Pupil, Closure of. Iris, Effects of certain narcotics upon , see Belladonna and Cataract. The follow- ing work upon the subject also merits atten- tion. C. Himly de la Paralysie dc V Iris par tine application locale de la Jusquiaume, el de son utililc dans le iraitemenl de plusieurs ma- ladies des Yeux, 2 de Ed. Altona , 1805. IRITIS. Inflammation of the iris. See Ophthalmy. ISCHU'RIA. (From ta-yje, to restrain ; and agsv, the urine.) A suppression, or stop- page of the urine. The distinction between a suppression and retention of urine, is practical and judicious. The former most properly points out a de- fect in the secretion of the kidneys ; the lat- ter, an inability ot expelling the urine when secreted. {Hey.) The first disease is not very common, is named ischuria rnialis, or suppression of urine, and belongs to the province of the physician ; the second is an exceedingly frequent disorder, is n a meiVisch uria vesi calls, or retention of urine , and its treatment is al- together surgical. Every thing relative to it will be found in the articles Catheter, and Urine, Retention of. ISSUE signifies an ulcer, made designed; ly by the practitioner, and kept open a cer- tain time, or even the patient’s whole life, for the cure, or prevention, of a variety of diseases. The physician, in his practice, has frequent occasion to recommend the making of an issue, and the surgeon finds it a principal means of relief in several important cases, as, for instance, the while swelling, the dis- ease of the hip-joint, caries of the vertebra?, &c. Many persons are never in health, or, at least, fancy themselves always ill, un- less they have an issue formed in some part of their body or another. The making of an issue, indeed, is not unfrequently consi- dered as an imitation of nature, who, of her own accord, often forms ulcers and abscesses in various parts of the body (as is not un- commonly conjectured) for the purpose of discharging pernicious humours, whereby people are supposed to be freed from griev- ous disorders, and have their health preserved. The humoral pathologists were excessively partial to these notions, which, at the pre- sent time, will be found by every experi- enced practitioner to influence the mass of mankind, and render the formation of issues more common, than perhaps is consistent with the better established principles of me- dical science. Few oid subjects will allow a sore of long standing to be dried up (as the expression is,) without requiring the surgeon immediately afterward to make tin issue for them. When an ulcer has existed a great length of time, the constitution may possibly become so habituated to it, that the health may really sutler from its being healed. 11 1 have often (says the experien- ced Dr. Parry) seen various thoracic affec- tions, a3 pulmonary consumption, asthma, carditis, or hydrothorax, arise from flic spontaneous, or artificial cure of ulcers, per- petual blisters, or fistula?.” {Elements of Pathology, fyc. p. 385.) Asthmatic com- plaints, severe headachs, he. are frequently observed to follow the cicatrization of an oid ulcer; but whether they would have happened, if an issue had been made in time, is a question difficult of positive de- termination ; for many persons with old ulcers are not prevented from suffering from asthma and headach. The plan of making an issue, however, is commendable both as rational and exempt from danger. Whatever may be the solidity of the theo- ries, which have been offered by medical writers, in regard to issues, the practitioner, who has his eyes open, cannot fail to see the benefit often derived from such means ; and if there be any unquestionable facts in me- dicine and surgery, we may confidently set down among them the frequent possibility of relieving one disease by exciting another of a less grievous, and more curable na- ture. There are two ways of making an issue ; one is with a lancet, or scalpel; the other with causlic. The place for the issue being fixed upon, the surgeon and his assistant are to pinch up a fold of the integuments, and with a lancet or knife, make in them an incision of suffi- cient size to hold a pea, or as many peas as may be thought proper. The pea, or peas are then to be placed in the cut, and cover- ed with a piece of adhesive plaster, a com- press, and bandage. The peas first inserted, need not be removed for three or four days, when suppuration will have begun ; but the issue is afterward to be cleaned and dressed every day, and have fresh peas put into it. The preceding is the ordinary method of making such issues as are intended to con- tain only one or two peas. When the issue is to be larger, which is generally proper, in cases of diseased verte bra?, white swellings, he., the best plan is to destroy a portion of the integuments with caustic. The caustic potassa, blended with quicklime, is mostly preferred for this pur- pose. The situation and size of the issue having been determined, the surgeon is to take care that the caustic does not extend its action to the surrounding parts. With this view, he is to take apiece of adhesive plaster, and having cut a hole in it of the exact shape and size of the issue intended to be made, he is to apply it to the part. Thus the plaster will defend the adjacent, skin from the effects of the caustic, while the uncovered portion of integuments, cor- responding to the hole in the plaster, is that which is to be destroyed. The caustic is to be taken hold of with a bit of lint, or tow, and its end, having been, a little moistened with water, is to be steadily rubbed upon the part of the skin where the issue is to be formed. The frictions ore to be continued till the whole surface, intended to be de- stroyed, assumes a darkish corroded appear- ance. The caustic matter may now be care- fully washed off with some wet tow. The HO JOINTS. plaster is to he removed, and a linseed poul- tice applied. As soon as the eschar is de- tached, or any part of it is loose enough to be cut away without pain, or bleeding, the peas are to be inserted and confined in their pro- per place with a piece of adhesive piaster. Some use beans for the purpose ; others, beads, which answer very well, and have the advantage of serving for any length of time, when washed and cleaned every day. If the issue is at all of a longitudinal shape, the peas, beans, or beads, may be more easily kept in their places, when a thread is passed through them. Issues ought always to be made, if possible, in a situation, where the peas will not he much disturbed in the ordinary motions of the body, nor interfere with the actions of muscles. The interspaces between the mar- gins and insertions of muscles, are deemed the most eligible places. Thus, issues in the arm are usually made just at the inferior an- gle of the deltoid muscle, by the side of the external edge of the biceps. In the lower extremities, issues are often made at the inner side of the thigh, immediately above the knee, in a cavity that may be readily felt there with the fingers. Sometimes, is- sues are made upon the inside of the leg, just below the knee. For the relief of any affections of the head or eye, the nape of the neck is commonly selected as a good situa- tion. In caries of the vertebras, they are made on each side of the spinous processes. In cases of diseased hips, they are formed in a depression just behind and below the tro- chanter major. When the nature af the dis- J J OINTS, DISEASES OF. The joints are subject to numerous diseases, which are more or less dangerous, according to their particular nature. Like ail other parts, the joints are liable to inflammation and abscess es ; their capsules frequently become distend- ed with an aqueous secretion, and the disease termed hydrops articuli is produced ; out, the most important of alt their morbid affec- tious, are the cases, which, a few years ago, were indiscriminately called white swellings, scrophulous joints, and the disease of the hip- joint. Here, as Mr. Brodie remarks, the same name has been frequently applied to different diseases, and the same disease has received different appellations. And confusion, with respect to the diagnosis, always gives,. rise to a corresponding confusion, with respect to the employment of remedies. Although, says he, diseases in their advanced stage ex- tend to all the dissimilar parts, of which the joints are composed, such is not the. case in the beginning. Here, as elsewhere, the morbid actions commence, sometimes in one, and sometimes in another texture, differing in their nature, and, of course, requiring to be differently treated, according to the me- uhanical organisation, and vital properties of order does not particularly indicate the situa-v tion for the issue, the ami should be preferred to the leg, as issues upon the upper extre- mities, especially the left arm, are much (ess annoying, than upon either of the lower, limbs. The great art of keeping an issue open, for a long while, consists in maintaining an equal and effectual pressure upon the peas, by which means, they are confined in their places, little depressions are made for them, and the gra- nulations hindered from rising. Compresses of pasteboard and sheet- iead will often be found highly useful. This plan is the surest one of preventing the issue from healing, and the most likely to save the patient all the severe and repeated suffering, which the fresh application of the caustic, or the use of sti- mulating powders, in order to renew the sore and repress the fungous flesh, unavoidably occasions. There is a method of making issues with the caustic made into a sort of paste, which is laid upon the part left uncovered by the adhesive plaster. It seems to me to be u more tedious and painful plan, and I do not recommencLil. It has been suspected, that the pain, arising from the caustic, might be lessened, by mix- ing opium with the application ; but, the idea seems not at a!! probable ; the destruction of a part of the skin must inevitably cause con siderable pain, with whatever substance it is produced, and opium itself, so far from being likely to diminish the agony, is itself a violent stimulus, whenever it comes into contact with.lhe exposed extremities of the nerve : . the part, in which they originate. (See Pathological and Surgical Ohs. on Diseases of the Joints, p. 2, 8vo Load. 1818.) It was this idea, which led Mr. Brodie to trace, by dis- section the exact parts, in which several of the principal di&eases of the joints commence, and how much light and discrimination his successful investigations have produced, it is needless for me here to insist upon, as his merit will long be appreciated by every sur- geon, who recollects the perplexity and ignorance which prevailed only a few' years ago in this very interesting branch of sur- gery. IVounds. — By the wound of a joint, surgeons mean a case, where the capsular ligament is penetrated, or divided. The injury is often accompanied with a division of the lateral., or other ligaments, and sometimes also w ith that ot the cartilages and hones. That the capsular ligament is u'ounded may generally be learned by the introduction of a probe, and frequently by a discharge of a transparent viscid fluid, called the synovia. But, as a similar discharge may proceed from mere wounds of the bursae mucosas, we might form an erroneous judgment, were we unac- quainted with the situation- of thc-so little JOINTS. 141 membranous bags, Boyer has seen several eases, in which a lluid, resembling synovia, was discharged from wounds of the sheaths of tendons. (See Trade des Maladies Chirurg, T. 4, p. 408.) Here, the advice which t have given in another place. (See Wounds of the Abdomen J respecting the temerity of being too officious with the probe, is equally im- portant, inasmuch as the rough introduction of this instrument into a large joint, like the Icnee, would be very likely to excite inflam illation of the synovial membrane, and a train of dangerous and even fatal consequences; while the information, gained by such em- ployment of the probe, is of little use ; be- cause, whenever a wound is suspected to reach into the caps .lar ligament, exactly the same treatment should alwas s be followed, as as if the joint were positively known to be penetrated. Notwithstanding simple wounds even of large joints often heal favourably, without any bad symptoms, this is not constantly the case, and the records of surgery furnish many examples, in which the most alarming and fatal consequences ensued. (See' Hunter's Commentaries, Part, 1, p. 69) When pro- perly treated, punctured wounds of the joints , 3 ys Boyer) are not in general attended with danger ; but, as some of these -v ounds, which were apparently quite simple, have bee?: fol- lowed by very bad symptoms, and even death, we should always be extremely circumspect in the prognosis. (See Traill des Mai. Chir. T. 4, p. 409 ) The treatment consist- in endeavouring to heal the injury by the first intention; in applying cold lotions; forbid- ding all motion of the part ; and employing bleeding and other antiphlogistic remedies. Baron Boyer relates two cases of punctured wounds of the elbo v joint, which h aied up in a few days, without any unfavourable symptom. He acknowledges, however, that these accidents do not always go on so Well, and that the consequences are sometimes pe- rilous. Simple incised wounds present only one indication ; viz. that of healing the part by the first intention. At the moment of the accident, some of the synovia is discharged, indicating that the capsular ligament i- wound- ed. Shouid this circumstance not have been noticed at first, tue surgeon may see the syno- via flow out again, if he move, or press upon the joint. But, in making this examination, the greatest gentleness should be used, lest tbe irritation of the capsular ligament be in- creased. When the wound is large, and there is no considerable thickness of soft parts, the articular surfaces are. exposed to view. The prognosis of an incised wound of a joint is not generally unfavourable, when the edges have been immediately brought together, the cavity of the joint has noi been long exposed, arid blood is not extravasated in it. This last danger is also exaggerated, as will be noticed, in speaking of collections of blood in joints. With these exceptions, says Boyer, the wound may heal as readily, as if the joint were not opened, and he has cited several facts in proof of this statement. Tls truth is also confirmed by the success which attend? operations, practised for the purpose of extracting cartilaginous substances from the knee. 'Nay very bad cases sometimes recover under judicious management, even thou, h the joint be large, and ab«ce-iSes fol- low. Thus I have seen in St. Bartholomew's hospital, within the last year (1820) two ex- amples of compound fractures oj the patella, where the opening in the capsule was >o large, that the finger could readily lie passed into the cavit) of the joint, yet alter large ab- scesses, a great deal of fever, and separation of none, the patients recovered with stiff joints. But, I would advise surgeon- not to let am facts of this kind prejudice their judgment in the Peatmen* ot gunshot wounds of the large joints, where, in the cireu mtam e- ehew lic e e\p|. lined (see Am- putation and Gunshot Wounds } amputation is the s.itest practice. In a sabie, or cut wound, the principal object is to heal the wound by the first intention. The res' of the treatment consists in using every possible means for the prevention ol inflammation, by perfect quie- tude of the part; the use of cold applica- tions. See. We repeat, however, that wounds of the joints do not always heai in (he above favour- able manner. Even among those cases, which appear the most slight and simple, .’here are but too many, which are billowed by such aggravated symptoms, aseither prove fatal, r occasion a necessity for amputation. And. in other instances of a le»s gri- vous description, when the patient is cured, the termination of danger is not without an an- chylosis by which the motion and functions ot tiie joint are permanently destroyed. The experienced Mr. Hey has noticed wounds ot tne joints, a id made some perti- nent rem rksou the subject. He states, that in these cases, the utmost care should be taken to prevent i Humiliation. “ Upon this circumstance chiefly depends a successful termination. I have seen (says he) many large wounds of the great joints healed with- out the supervention of any dangerous symp- toms, where due care has been taken to pre- vent inflammation; whilst injuries, apparently trifling, will often be followed by a train of distressing and dangerous consequences, wnere such care has been neglected. It is, generally, easier to prevent inflammation in the joints, after a wound, than to arrest its progress when once begun I speak now of inflammation affecting the capsular ligament. A siigiit degree of redness and tenderness in the integuments only is of little conse- quence; bus, when the capsular ligament becomes inflamed, the formation of abscesses attended vvitu a high degree of lever, and ultimately a stiffness of the joint, are the common consequences, if the life of the pa- tient is preserved.” (See Hep's Practical Observations in Surgery, p. 354, Edit. 2.) For facts, in confirmation of the loregoing account, I particularly refer the reader to se- veral cases recorded in this last publication,' p. 355, etseq. and by Boyer . (Traitd des Mat, Chir. T. 4, p. 426, fyc.) joints. 142 When the large joints, particularly the knee, are wounded, the stomach is frequently very much affected. I remember being shown by Mr. Best of Newbury, a man, who. in his oc- cupation as a wheelwright, happened to give himself a wound by whit b one side of the knee was laid open : a good deal <>f inflam- mation and suppuration ensued; but, what particularly struck me, nay the manner in which the tfinn complained of the affection of his stomach. in speaking ot cartilaginous substances in t he joints,! shall have occasion to advert again to the danger attendant on wounds of these parts ; and the same fact is still further con- sidered, in the articles .’imputation, Disloca- tions, Fractures, and Gunshot Wounds, in which last part of the D ciionary, tlie senti- ments ot Baron Larrey, and other writers on military surgery, ate laid before the reader. Inflammation of Joints, if we exclude from consideration specific cases, may be said usually to be the consequence of a contusion, sprain, wound, or some other kind of injury : out with respect to the inflammation of the synovial membrane, as described by Mr. Bro- die, no cause is so frequent, as the application of cold, and hence he explains the frequency of this disease in the knee, and its rarity in the hip and shoulder, which are covered with a thick mass of flesh. As a late writer ob- serves, the inflammation, arising from a wound, is infinitely the most severe after it has once commenced. ( James on Inflam- mation, p. 157.) ihe inflamed joint shows thecommonsymp- toms of inflammation; viz. preternatural redness, increased' heat, throbbing, pain, and swelling, while the constitution is also dis- turbed by the common symptoms of inflam- matory fever, it deserves notice, however, that in these cases, the constitutional symp- toms are often exceedingly severe, and the pulse is more frequent, and less full and ' trong, than when pans, more disposed to return to a stale of health, are affected. The inflammation first attacks some part of the capsular ligament, and very quickly spreads over its whole extent, as usually happens in all inflammations of smooth serous mem- branes. The capsules of the joints are naturally not very sensible ; but, like many other parts si- milarly circumstanced, they often become acutely painful, when inflamed. The com- plain! is accompanied with an increased se- cretion ot the synovia, which becomes of a more aqueous, and of a less albuminous qua- lity, than it is in the healthy state. lienee, *itis not so well calculated for lubricating the articular surfaces, and preventing the effects ol friction, as it is in (he natural condition of the joint ; a circumstance, which may ex- plain, why a grating sensation is often per- ceived on making the patella. The capsular ligaments, like other parts, are frequently thickened by inflammation, and sometimes, coagulating lymph being effused on their internal surfaces, organized cartilaginous, or osseous bodies, arc formed within the joints. * It has been explained by Mr. Brodie, that the usual consequences of inflammation of the synovial membrane, or capsular liga- ment, are ; 1. a preternatural secretion of synovia, 2. an effusion of coagulating lymph into the cavity of the joint. 3. a thickening of the synovial membrane, a con- version of it into a substance rdSembling grisde, and an effusion of coagulable lymph, and probably of serum into the cellular structure, by which it is connected with the external parts. The same gentleman has seen several cases, where, from the appear- ance of the joint, and the symptoms, there was every reason to believe, that the in- flammation had produced adhesions of the reflected fold of the membrane to each other: and, in dissection, he has occasion- ally observed adhesions which might have arisen from inflammation at some former period. u These effects of inflammation of the synovial, very much resemble those of inflammation of the serous membranes. There are, however, some points of differ- ence. In the former, I have reason to be- lieve, that suppuration rarely takes place independently of ulceration ; but, this is u frequent occurrence in the latter. Inflam- mation of the peritonaeum, or pleura, though very slight in degree, and of very short du- ration, terminates in the effusion of coagu lable lymph ; but it is only violent or long- continued inflammation, which has this ter- mination in the membranes of joints ( Bro- die in Med. Chir. Trans. Vol. 4, p. 216.) When the inflammation attains a high pitch, an abscess may occur in the capsular ligament, which at length ulcerates, and the pus makes its way beneath the skin, and is, sooner or later, discharged through ulcerated openings. An abscess rarely takes place in an im- portant articulation, in consequence of acute inflammation, without the system being also so deranged that life itself is imminently endangered. Severe febrile symptoms always atflict the patient, and occasionally, delirium and coma taking place, death itself ensues. Two rapidly fatal cases of ulcera- tion of the synovia! membrane, where mat- ter had formed within it from a sprain of the hip, and a contusion of the shoulder, are recorded by Mr. Brodie. (See Pathol. Chir. Obs. p. 65 ) In these cases, the inflammatory fever is very quickly converted into the hectic; in- deed, when an abscess has taken place in a large joint, in consequence of acute inflam- mation, hectic symptoms almost immedi- ately begin to show themselves, and the strong actions of the common inflammatory fever suddenly subside,; t , « Local consequences, even worse than those above described, may follow inflam- mation of a joint. As the layer of the cap- * solar ligament, reflected over the cartilages of the articulation, is often inflamed, the cartilages themselves may Imvc the inflam- mation communicated to them. Parts of a cartilaginous structure, being very incapa- ble of bearing the irritation of disease, often JOINTS* 143 ulcerate, r, hi other words, arc absorbed, so as to leave a portion, or the whole, of the articular surface of the bones, completely denuded of its natural covering. At length the heads of the bones themselves inflame, and become carious; or the consequence may be anchylosis. Mr. Brodie has seen some cases in which there was exten- sive destruction of the cartilages, apparently in consequence of neglected inflammation of the synovial membrane ; but he believes, that in most cases where ulceration of the cartilage is combined with such inflamma- tion, the former is the primary affection, and the latter takes place subsequently, in consequence of the formation of an abscess within the joint ( Pathol . and Surg. Obs. fyc.p. 17.) According to Mr. Brodie, who speaks chiefly of the inflammation which begins in the synovial membrane itself, and is not communicated to it from other tex- tures, the disease very seldom attacks young children, but is frequent in adult persons, the reverse of what happens in some other diseases of the joints. The inflammation of the capsular liga- ment, or synovial membrane, frequently assumes the chronic form, and is then very often confounded with other more serious maladies, under the general appellation of white swelling. The disease often arises from cold, and hence is more common in the knee and ankle than in the hip or shoulder. It may also arise from the immo- derate use of mercury, and, in particular constitutions, from rheumatism and general debility of the system. In these instances it often leaves one joint and attacks ano- ther ; and it is less severe, and less disposed to produce effusion of coagulating lymph, or a thickened state of the membrane, than when it is apparently a local disease. (Bro- die, in Med. Chir. Trans. Vol. 4. p. 218.) In the latter case the disorder is more likely to assume a severe character, and may be of long duration, leaving the joint with its functions more or less impaired* and occa- sionally terminating in its total destruction. The following are the chief symptoms of the complaint, pointed out by Mr. Brodie. At first, although some pain is felt over the whole joint, the patient refers it principally to one spot, and it is not at its height be- fore the end of a week or ten days. Some- times, even at this period, the pain is trifling, but sometimes it is considerable, and every motion of the joint is distressing. In a day or two after the commencement of the pain, the joint is affected with swelling, which at first arises entirely from a collection of fluid in its cavity, and, in the superficial joints, an undulation may be distinguished. However, after the inflammation has pre- vailed some time, the fluid is rendered less j perceptible, either in consequence of the • synovial membrane being thickened, or the effusion of lymph ; and the more solid the swelling is, the more is the mobility of the I joint impaired. The form of the diseased j| joint does not correspond to that of the | brads of the bones ; but, as the swelling is chiefly caused by the distention of the syno- vial membrane, u its figure depends in a great measure on the situation of the liga- ments and tendons, which resist it -in certain directions, and allow it to take place in others. Thus, when the knee is affected, the 3" ellingis principally observable on the anterior and lower part of the thigh,” where there is only a yielding cellular structure between the extensor muscles and the bone. “ It is also often considerable in the spaces, between the ligament of the patella and the lateral ligaments, because at these points the fatty substance is propelled outward by the collection of fluid. In the elbow, the swelling occurs principally above the ole- cranon, under the extensor muscles of the forearm ; and in the ankle, it is between the lateral ligaments and the tendons in front of the joint. In the hip and shoulder, where the disease is less frequent, the fluid cannot be felt, but the swelling is percepti- ble through the muscles. In the beginning of this disease in the hip, a fulness both in the groin and nates may be remarked ; but afterward the nates become flattened, and the glutaei wasted from want of use. The pain is usually confined to the hip. but Mr. Brodie has seen cases in which it was also referred .to the knee. It may be discrimina- ted from the case in which the cartilages of the hip are ulcerated, by observing, that the pain is more severe in the beginning than in the advanced stage of the disease ; it never amounts to the excruciating sensation felt in the other disease ; and it is aggravated by- motion, but not by pressing the cartilagi- nous surfaces against each other. The wasting of the glutaei is also preceded by a fulness of the nates. After the inflammation has subsided, the fluid is absorbed, and the joint frequently regains its natural figure and mobility; but, in the majority of cases, stiffness and swelling remain, and the pa- tient continues very liable to relapse, the pain returning, and the swelling being aug- mented, whenever the patient exposes him- self to cold, or exercises the limb a great deal. In cases where the synovial mem- brane is thickened, a slow kind of inflam- mation sometimes continues in the part, notwithstanding the fluid has been absorbed, and the principal swelling has subsided, the disease at length extending to the cartilages, suppuration taking place, and the articular surfaces being completely destroyed. Ac- cording to Mr. Brodie, in this advanced stage, the history of the disease, and not its present appearance, is the only thing by which one can learn whether the primary affection was inflammation of the synovial membrane, or ulceration of the cartilages. Though such is the most common character of inflammation of the synovial membrane, it is admitted, that its nature is sometimes more acute, exhibiting the symptoms men- tioned at the beginning of this section. (See Brodie' s Pathol, and Surg. Obs. p. 21, fyc.') It is remarked by Mr. Wilson, that, when coagulable lymph is effused, the whole of k docs not always adhere to the inflamed JOINTS'. 344 face, but some of it forms flakes which float in the fluid within the joint in masses large enough to be sometimes felt through the capsular ligament. In other instances, the lymph becomes solid, adheres to the inside of the synovial membrane, and becomes vascular. The surface of this adventitious coating is sometimes smooth ; but, occa- sionally, it forms thick projecting masses, of different degrees of thickness and length, and so numerous as to conceal every part of the original smooth surface of the synovial membrane, as exemplified in a preparation in Windmill-street. (On the Skdeton and Diseases of Bones and Joints, p. 319.) When inflammation of the synovial mem- brane has arisen from a protracted or ill- conducted course of mercury, Mr. Brodie recommends a trial of sarsaparilla ; and when the disorder is connected with rheu- matism, the medicines advised are opium with diaphoretics, preparations of colchi- eum autumnale, and other usual remedies for rheumatic complaints. In some instan- ces, however, in which several joints were affected, this gentleman has known benefit derived from moderate doses of mercury, ( p . 31.) But whether the disease be local, or dependent on the state of the constitu- tion, Mr. Brodie considers topical remedies of most importance. It will considerably shorten what we have to say concerning the treatment of inflamed joints, to observe, that, in the acute form of inflammation of the synovial membrane, the antiphlogistic plan, in the full sense of the expression, is to be strictly adopted. But, as there is a variety of means often, adapted to the same purpose, it seems necessary to offer a few remarks on those which Jay the greatest claim to our commendations. There are few other surgical cases in which general, and especially topical, bleed- ing is more strongly indicated. The vio- lence of the inflammation, and the strength, age, and pulse of the patient, must deter- mine with regard to the use of the lancet ; but the application of leeches may be said to be invariably proper. When the leeches fall off, the bleeding is to be promoted by fomenting the part. The surgeon should daily persist in this practice, until the acute stage of the inflammation has subsided. As Mr. Brodie observes, attention should also be paid to the state of the bowels, and saline draughts and diaphoretic medicines be exhibited. ( Pathol . and Surgical Obs. p. 32.) In conjunction with this treatment, the iotio plumbi acetatis must be employed. In a few instances, however, the patient seems to derive more ease and benefit from the employment of fomentations and emol- lient poultices, which, according to Mr. Brodie, is the case when the swelling has been produced rapidly, and is attended with considerable tension. But, on this point, as I have remarked in speaking of Inflamma- tion, the feelings of the afflicted should always be consulted ; for, if the pain be ma- terially alleviated bv this or that application, pc employment will hardly ever be wrong Nothing more need be said concerning the rest of the treatment, proper during the vehemence of the inflammation, as the duty of the surgeon is not materially differ- ent from what it is in other inflammatory cases. As soon as the acute stage of the affection has subsided, the grand object is to remove the effects which have been left. These are a thickened state of the capsular liga- ment, and parts surrounding the articu- lation ; a stiffness of the joint, and pain when it is moved ; fluid in the capsule, &c. At first, as Mr. Brodie has observed, the joint should he kept perfectly quiet, and blood should be several times taken from the part, by means of leeches and cupping. The latter is the method to which the preceding writer expresses the preference. The use of cold evaporating lotions is also to be con- tinued until the inflammation has further abated, when a blister may be applied, and. kept open with the savin cerate, or a repeti- tion of blisters kept up, as preferred by Mr Brodie. “ l he blisters (he says) should be of considerable size ; and if the joint be deep-seated, they may be applied as near to it as possible; but, otherwise, at a little dis- tance. Thus, when the synovial membrane of the hip is affected, they may be placed on the groin and nates ; but, when that of the wrist is inflamed, they should be applied to the lower part of the forearm. Mr. Brodie thinks blisters have more effect than any other means, in removing the swelling ; but, excepting in very slight cases, he very rightly condemns their use, unpreceded by the abstraction of blood. After the subsi- dence of the inflammation, moderate exer- cise of the joint, and stimulating liniments are recommended. The camphor liniment is to be strengthened with the addition of liquor ammonia?. or tinctura lyttm, or thf following formula, adopted as that to which the above gentleman seems to give the pre- ference. p,. Olei olivae ^rss. acid, sulpli. 3 s ?- M. He speaks also favourably of the effects of the antimonial ointment, in the proportion of 3j. of the antim. tart, to gj. ung. cetacei. Plasters of gum ammoniac'' he regards a> sometimes useful in preventing relapsus. Issues and setons are never serviceable, un- less ulceration of the cartilages has begun. For the removal of the remains of the swell- ing and stiffness, Mr. Brodie joins other writers in praising the efficacy of friction and exercise. The friction may he made with camphorated mercurial ointment, or with powdered starch ; but the friction is to be employed with caution, as otherwise it may produce a return of the inflammation. When this happens, it is to be discontinued, and blood taken from the part. On the whole, Mr. Brodie appears to consider fric- tion better adopted to cases, where the stiff- ness depends upon the state of the external parts, than in others, where it arises from disease in the joint itself. With respect to the plan of allowing a column of warm wa - ter to fall on the part, as suggested by Lo T'rau, and practiced «t. the v'atermg-plucr?. JOINTS. 146 he allows, that it is beneficial, but that it rc- quires the same caution as the employment of friction. {Pathol, and Surg. Obs.p. 30, tyc.) 1 have met with several instances, in which lotions, composed of vinegar and muriate ot ammonia, sufficed for the removal of the chronic complaints, left after the acute stage of the disorder. The severity of the constitutional symp- toms is mostly, if not always, greater, when the inflammation of a large joint arises from a wound, than when it is the consequence of a bruise or sprain. Loose cartilages in joints . — Hard, roundish, or flattened bodies, mostly of a cartilaginous nature, are sometimes formed within the cap- sular ligaments, occasioning more or less pain in the affected joints, and a considera- ble impediment to the freedom of their movements. The disorder, though not no- ticed by any of the very ancient writers, is far from being uncommon. Pare is the first who speaks of it : he says, that a hard, polish- ed, xokite body, of the size of an almond , was discharged from the knee of a patient, in the year 1558, in which be had made an inci- sion for an aqueous aposlume, (without doubt an hydrops articuli.) {Lie. 25, chap. 15, p. 772.) A hundred and thirty-three years afterward, viz. in 1691, Pechtin published the full details of another case, in which a cartilaginous body was successfully extracted from the knee. ( Observat . Physico-Med. Obs. 38, p. 306.) Dr. Alexander Monro in 1726, dissected the knee-joint of a woman, who had been hung, and found in the articu- lation a cartilaginous body, of the shape and size of a small bean. These were the only examples of the disease known before the year 1736, at which period Mr. Simson cut out of the knee a similar substance, which he supposed at the time of the operation was only beneath the skin. (See Edinb. Med Essays, Vol. 4.) Since the publication of this last case, the disease has been several times met with in England by Bromfield, Hewit, Middleton, Gooch, Ford, Home, Bell, Aberneihy, &sc. ; in Germany, by Henckel, Theden, Loeffler, &c. ; and in France by Desault, Sabatier, and many , other practitioners. Hence, as Boyer remarks, this disorder is now as well known, as most others, to which the joints are subject. (Traitc des Mai. Chir. T. 4, p. 434.) Such detached and moveable cartilages are not peculiar to the knee, as they occur in other joints ; yet they are most frequently met with in the knee, and it is in this joint that they produce symptoms, which render them the object of a chirurgical operation. Morgagni and B. Bell met with them in the ankle ; Haller in the joint of the jaw ; and Hey in the elbow. According to Sir Everard Home, these substances are analogous in their structure to hone j but in their external appearance, (hey bear a greater resemblance to cartilage. They are not., however, always exactly of ■ he same structure, being in some instances Vol. II, i y softer than in others. Their external sur- face is smooth and polished, and, being lu- bricated by the synovia, allows them to be moved readily from one part of the joint to another. They seldom remain long at rest, while the limb is in motion ; and when they happen to be in situations where they are pressed upon with force by the different parts of the joint, they occasion considera- ble pain, and materially interfere with its necessary motions. The circumstance of their being loose, and having no visible' attachment, made it difficult to offer good conjectures respecting their formation ; and, according to Sir E. Home, no satisfactory account of their origin had been given, when Mr. Hunter made his observations. In the course of his experiments, instituted with a view to esta- blish a living principle in the blood, Mr. Hunter was naturally induced to attend to the phenomena, which took place, when that fluid was exlravasated, whether in con- sequence of accidental violence, or other circumstances. The first change he found to be coagulation ; and the coagulum thus formed, if in contact with living parts, did not produce an irritation similar lo ex- traneous matter, nor was it absorbed and taken back into the constitution, but in many instances preserved its living princi- ple. and became vascular, receiving brandi- es from the neighbouring blood-vessels for itssupport; it afterward underwent changes, rendering it similar to the parts to which it was attached, and which supplied it with nourishment. When a coagulum adhered to a surface, which varied its position, the attachment was rendered in some instances pendulous, and in others it was entirely broken. Hence, it was easy to explain the mode, in which those pendulous bodies are formed, which are sometimes attached to the inside of circumscribed cavities, and the principle being established, it became equally easy for Mr. Hunter, to apply it under other cir- cumstances, since it is evident from a known law in the animal economy, that extravasa- ted blood, when rendered an organized part of the body, can assume the nature of the parts into which it is effused, and conse- quently, the same coagulum, which, in an- other situation might form a soft tumour, would when situated on a bone, or in tlm neighbourhood of bone, often form a hard one. The cartilages, found in the knee- joint, therefore, appeared to him to originate, from a deposit of coagulated blood upon the end of one of the bones, which had ac- quired the nature of cartilage, and had afterward been separated. This opinion was further confirmed by the examination of joints which had been violently strained, or otherwise injured, where the patients had died at different periods after the accident. In some of these cases, there were small projecting parts, preternatu rally formed, as hard as cartilage, and so situated, as to bo readily knocked off' by any sudden or violent, motion of the joint. (Trans, for the 146 JOINTS. Improvement of Med. and Chir. Knowledge, Vol. 1 .) Mr. Brodie met with two cases, however, in which the loose bodies were of a different nature, and had a different origin from that referred to by Sir. E. Home. Sometimes disease causes a bony ridge to be formed, like a small exostosis, round the margin of the cartilaginous surfaces of the joint. In the two examples alluded to, this preterna- tural growth of bone had taken place, and in consequence of the motion of the parts, portions of it had been broken off, and lay loose in the cavity of the joint. ( Brodie in Med. and Chir. Trans. Vol. 4 p. 276.) And, in a more recent publication, he remarks, that, in the majority of cases, which he has met with, no inflammation preceded the formation of these preternatural substances, and, therefore, he thinks it probable, that, in some instances, they are generated, like other tumours, by some different process. He further observes, that they appear to be situated originally either on the external sur- face or in the substance of the synovial membrane, since, before they become de- tached, a thin layer of the latter may be traced over them. ( Pathological and Sur- gical Obs. p. 298.) One or more of these preternatural bodies may be formed in the same joint. Sir E. Home mentions one instance, in which there were three ; they are commonly about the size of a horsebean, often much smaller, and sometimes considerably larger ; when very large, they do not give so much trouble to the patient as the smaller kind. A sol- dier of the 56th regiment had one nearly as big as the patella, which occasioned little uneasiness, being too large to insinuate it- self into the moving parts of the joint. Morgagni saw twenty-live in the left knee of an old woman, who died of apoplexy ; and Haller met with no less than twenty in the articulation of the lower jaw. When there are several in the same joint, it is observed, that their size is generally small. (Boyer, Traitd des Mai. Chir. T. 4, p. 436.) The diagnosis of this disease, as Boyer observes, is seldom attended with any diffi- culty. When the formation of the extrane- ous substances follows a fall, or blow upon the joint, the complaint begins with a swell- ing of the surrounding soft parts, and upon the subsidence of this swelling, which lasts for a time more or less long, the presence of the little cartilaginous tumours is indica- ted by certain symptoms which are peculiar to them. In persons who have had no blow, nor fall upon the knee, the disease some- times commences with a more or less acute pain in the joint, with or without swelling of the surrounding soft parts, and which affec- tion is usually regarded as rheumatism. To these first symptoms, which are common both to cases of foreign bodies in the joints, and other diseases of these parts, are soon added other particular signs, by which the nature of the case is evinced. As the extraneous bodies are in general free and moveable in the joint, they can easily be made to slip about from one part of ihe articulation to another: a circum- stance, which is facilitated by the smooth- ness of their surface, as well as by the syno- via, which is mostly in larger quantity than natural. According to the situation, which they happen to occupy, sometimes they produce acute pain ; sometimes no pain whatever. When they lodge in a depression, where they are not compressed, they cause no pain ; and if they could be always kept in this position, their presence would not be likely to excite any inconveniences. But, when they get between the articular sur- faces which in certain postures of the limb come into contact with each other, the fol- lowing are the effects of the compression. Sometimes, the extraneous substance sud- denly glides between the condyles of the thigh bone and head of the tibia, and while it lodges there, excites acute pain in certain directions of the limb, and instantaneous loss of the power of moving the knee. But, when it shifts its place again, either naturally, or accidentally, during an examination of the affected part, the compression is removed, the pain all at once ceases, and the functions of the joint are as suddenly restored. Most frequently, when the extraneous body gets behind the patella, or the ligament of the pa- tella, as the patient is walking, he is com- pelled to make a sudden stop, and would fall down from the acuteness of the pain, if nothing were at hand to save him. Some patients have been observed, however. who experienced no pain in these circumstances. Reimarus mentions a man, who suffered great pain, and could not move his leg, when the extraneous body was at the side of the joint ; but was immediately relieved by push- ing it under the patella. B. Bell met with cases, in Which the pain was so violent at the instant when the patients put their legs in certain postures, that fainting was brought on, and they wen- so afraid of a return of the suffering, that they preferred remaining per- fectly quiet to running any risk of causing the pain again. He even asserts, that he had known some persons, in whom the least motion of the limb would cause such pain as awoke them out of the deepest sleep. The pain, excited by the situation of the extrane- ous body betwixt the articular surfaces, re- curs at intervals more or less long, and always in consequence of some motion, or exertion Sometimes it ceases directly by the effect of a movement, contrary to that which produced it ; but most frequently it continues, and then the surrounding soft parts are affected with swelling, which obliges the patient to keep his bed, and have re- course to emollient anodyne applications. Sometimes, as I have already noticed, the foreign body lies at a part of the joint, , where it causes no inconvenience, and makes no pressure on the articular surfaces. In this case, all the symptoms have been known to cease for several months, so that the patient imagined himself cured, when suddenly, the foreign body was urged by some effort into another situation, where if JOINTS. 147 occasioned a renewal of all the former pain. The foregoing circumstances afford strong presumptive evidence of the presence of ex- traneous cartilaginous substances in the joint ; but, they do not amount to certainty ; this can only be acquired by the touch. In handling the knee of the patient, the surgeon feels a hard, prominent substance, which slips about under his fingers, and glides under the patella, or the ligament of this bone, and sometimes under the tendon of the extensor muscles of the leg, from one side of the joint to the other. The extraneous body may make its appearance either at the inside or the outside of the articulation ; but, it most frequently presents itself at the former part, which is the broadest and most sloping, while the capsular ligament there is loosest. Desault met with one instance, in which the capsular ligament and soft parts were so loose, that the patient could turn the extra- neous substance round and round. In general, the complaint is not danger- ous ; but, as it is painful, and obstructs, or often prevents walking ; and usually can be cured only by an operation, which has some- times had fatal consequences ; we cannot be too much upon our guard in delivering a prognosis. It 4s only in the knee, that the disease ever becomes so troublesome as to require an ope- ration, or, indeed, any surgical treatment. If we except making an incision into the joint, for the purpose of extracting the carti- laginous tumours, we are not acquainted with any certain means of freeing a patient from the inconvenience of the complaint. To this plan, the danger attendant on all wounds of so large an articulation as the knee, is a very serious objection. Middleton and Gooch endeavoured to conduct the extraneous body into a situation, where it produced no pain, and to retain it in that position a long time by bandages, under the idea, that the cartilaginous substance would adhere to the contiguous parts, and occasion no future trouble. Some will be inclined to think, that no positive conclusion ought to be drawn from the cases brought forward by these gentlemen, because they had no op- portunity of seeing their patients again at the end of a reasonable length of time, and we know, that loose cartilages in the joints sometimes disappear for half a year, and then make their appearance again. Yet, perhaps, the very circumstance of the pa- tients not applying again, may justify the inference, that sufficient relief had been ob- tained. However, it should not be concealed, that this method was also tried in St. George’s Hospital without benefit, and that in one case, the pain was increased by it. (See lieimarus de Fungo Jlrticulorum, § 27, 54, §'C-) Mr. Hey, aware of the dangerous symp- toms, which have occasionally resulted from the most simple wounds penetrating the knee-joint, was induced to try the efficacy of a laced knee-cap. and the cases, which he has adduced, clearly demonstrate, that the benefit thus obtained, is not temporary, at least, as long as the patient continues to wear the bandage. In one case, the method had been tried for ten years, with all the success which the patient could desire. Boyer also made one patient use a knee-cap for a year ; after which it was left off, the patient appearing cured. And, in a second instance, the same practitioner tried the plan, which put a stop to the pain, and enabled the patient to walk with ease; but it was not known whether the method was properly continued, as the patient had not latterlv been seen. {Boyer, Traiti des Mai. C/iir. T. 4, p. 444.) Contemplating the evidence upon this point, and the perilous symptoms, sometimes following wounds of the knee-joint, I am decidedly of opinion, that the effect of a knee-cap, or of arollerand compress, applied over the loose cartilage, ought generally to be tried, before having recourse to exci- sion. I say generally, because the conduct of the surgeon ought, in such cases, to be adapted to the condition and inclination of the patient. If a man be deprived of his livelihood, by not beingable to use his knee ; if he cannot, or will not take the trouble of wearing a bandage ; if he be urgently de- sirous of running the risk of the operation after things have been impartially explained to him ; if a bandage should not be produc- tive of sufficient relief ; and lastly, if exces- sive pain, severe inflammation of the joint, a great deal of symptomatic fever, and lameness, should frequently be produced by the complaint, (See Brodie's Pathological and Surg. Obs p 299,) I think it is the duty of a surgeon to operate. It is very certain, that success has generally attended the ope- ration ; but, small as the chance is of losing the limb, and even life, in the attempt to get rid of the disease, since the inconveniences of the complaint are, in most cases, very bearable, and are even capable of palliation by means of a bandage, endangering the limb and life in any’’ degree, must seem to many persons contrary to the dictates of prudence. At all events, we must agree with Boyer, that, as a laced knee-cap can do no harm, we ought always to make trial of it, and never perform the operation, ex- cept when pressure does not answer, and the return of frequent and violent pain makes the employment of the knife necessa- ry. (See Traiti des Mai. Chir. T. 4, p. 445.) I am ready to allow, with M. Brochier, that the danger attendant on wounds of the large joints, has always been exaggerated in consequence of ancient prejudices. ( De- sault's Journ. Vol. 2.) But, making every allowance for the influence of prejudice, a man must be very sceptical indeed, who does not consider the wound of so large a joint as the knee, attended with real cause for the apprehension of danger. See Case 2, in my Treatise on the Diseases of the Joints. At the end of Mr. Ford’s case, (Med. Obs, and Inquiries , Pol. 5.) we read on the subject of cutting loose cartilages out of the knee : 148 joints. t: The society have been informed of several cases, in which the operation has been per- formed ; some, like this, have healed up without any trouble ; others have been fol- lowed by violent inflammation, fever, and death itself.” The history of a case has lately been published, in which the patient very nearly lost his life from suppuration in the knee-joint after this operation. (See Kirby's Cases , p. 76.) in the same work, reference is also made to two other cases, which actually had a fatal termination ; (p. 82:) and even in Mr. Kirby’s own instance, the recovery was not effected, without the entire loss of the motions of the knee. As the disorder is often attended with a degree of heat and tenderness in the articula- tion ; as the danger of the operation is, in a great measure, proportioned to the subsequent inflammation ; and, as much of the danger is at once removed, if the wound unite by the first intention ; the advice to keep the patient in bed a few days before operating, to apply leeches and cold saturnine lotions to the knee during the same time, and to exhibit beforehand a saline purgative, is highly prudent. I shall next introduce an account of the plan of operating, as described by several of the best modern surgeons. “ As these loose bodies cannot always be found, no time canbe fixed for the operation ; but the patient, who will soon become familiar with his own complaint, must arrest them when in a favourable situation, and retain them there till the surgeon can be sent for. “ Before the operation, the limb should be extended upon a table in an horizontal position, and secured by means of assistants ; the loose cartilages are to be pushed into the upper part of the joint above the patella, and then to one side ; the inner side is to be preferred, as in that situation only the vastus mternus muscle will be divided in the ope- ration. Should there be several of these bodies, they must be all secured, or the ope- ration should be postponed till some more favourable opportunity, since the leaving of one will subject the patient to the repetition of an operation, not only painful, but attended with some degree of danger. “ The loose bodies are to be secured in the situation above-mentioned by an assis- tant, a task not easily performed while they are cut upon, from their being lubricated by the synovia ; and if allowed to escape into the general cavity, they may not readily, if at all, be brought back into the same situa- tion. “ The operation consists in making an incision upon the loose cartilage, which it will be best to do in the direction of the thigh, as the wound will more readily be healed by the first intention. If the skin is drawn to one side, previously to making the incision, the wound through the parts under- neath will not correspond with that made in the skin, which circumstance will favour their union. The incision upon the cartilage must be made with caution, as it will with difficulty be retained in its situation if much force is applied. The assistant is to endea- vour to push the loose body through the opening, which must be made sufficiently large for that purpose ; but as this cannot always be done, the broad end of an eyed probe may be passed under it, so as to lift it out, or a sharp-pointed instrument may be stuck into it, which will fix it to its situation, a> d bring it more within the management of the surgeon. “ The cartilages being all extracted, the cut edges of the wound are to be brought together, and, by means of a compress of lint, not only pressed close to one another, but also to the parts underneath, in which situation they are to be retained by sticking plaster, and the uniting bandage. “ As union by the first intention is of the utmost consequence after this operation, to prevent an inflammation of the joint, the patient should remain in bed with the leg extended, till the wound is perfectly united, or at least all chance of inflammation at an end.” ( Home , in Trans, for the Improvement of Med. and Chir. Knowledge, Vol. 1 ,p. 239, fyc.) In one instance, Desault proceeded in the following manner : the surgeon, after relax- ing the capsular ligament by extending the leg, brought the extraneous body on the in- side of the articulation against the attachment of the capsular ligament, and secured it in this situation, between the index finger and thumb of the left hand, whilst an assistant drew the integuments forwards towards the patella. The parts, covering this extraneous body, were now divided by an incision one inch in length, and its extraction accomplish- ed by pushing it from above downwards, and raising it inferiorly with the end of the knife. This substance, on examination, was found similar in colour to the cartilages that cover the articular surfaces: it was three- quarters of an inch in length, six lines and a half in width, and three lines in thickness : its surfaces were smooth, one concave and the other convex : its circumference irregu- lar, disseminated with red points, forming small depressions ; the inside was ossified, the outside of a cartilaginous texture. As soon as the substance was extracted, the assistant let go the integuments which he had drawn forwards ; they consequently- returned to their natural situation, on the inner side of the knee-joint, in such a man- ner, that the external wound in the integu- ments was situated more inward, than the one in the capsular ligament. Two advanta- ges were procured by this means : on the one hand, air was prevented from penetra- ting into the articulation ; and on the other, the floating portion of capsular ligament, retained inwards by the skin, was more like- ly to attach itself to the condyle, in case it did not unite to the other portion of the cap- sule divided near its attachment. The edges of the wound were brought into contact by means of a uniting bandage ; dry lint and compresses were applied, and retained on the part by a slight bandage : and the limb JOINTS. 149 was kept in a siate oi extension. (. Desault's Journal , T. 2.) According to Mr. Abernethy, the inner surface of the internal condyle of the os femoris presents an extensive and nearly a plain surface, which terminates in front and at its upper part by an edge which forms a portion of a circle. If the points of the finger be firmly pressed upon this edge so as to form a kind of line of circumvalla- tion round these (cartilaginous) bodies, they cannot pass into the joint in this direction, nor can they recede in any other, on account of the tense state of the internal lateral li- gament. Here these substances are near the surface, and may be distinctly felt: and they may be exposed by simply dividing the integuments, fascia, and the capsule of the joint. In an interesting case, which Mr. Aber- nethy relates, the integuments of the knee were gently pressed towards the internal condyle, and the fingers of an assistant ap- plied round the circular edge of the bone. The integuments were gently drawn to- wards the inner ham string, and longitudi- nally divided, immediately over the loose substance, to the extent of an inch and an half. This withdrawing of the integuments from their natural situation was designed to prevent a direct correspondence of the ex- ternal wound to that in the capsule of the joint : for, when the integuments were suf- fered to regain their natural position, the wound in them was nearer to the patella, than the wound in the capsule. The fascia, which covers the joint, having been expo- sed by the division of the integuments, it was divided in a similar direction, and near- ly to the same extent. The capsule was now laid bare, and gently divided to the ex- tent of half an inch, where it covered one of the hard substances, which suddenly slipped through the opening, and by press- ing gently upon the other, it was also dis- charged. The bodies, thus removed, were about three-quarters of an inch in length, and half an inch in breadth. They had a highly polished surface, and were hard like cartilage. The fluid contained in the joint was pressed toward the wound, and 'about two ounces of synovia were discharged. The wound of the integuments was then gently drawn towards the patella, and ac- curately closed with sticking plaster. ( Sur- gical Observations. 1804.) When there are several extraneous carti- laginous bodies in the joint operated upon, the surgeon ought to extract them all through the same wound, if it can be done without producing too much irritation of the capsu- lar ligament, and they will admit of it. But, frequently, only one can be made to pre- sent itself at a time, or can bt easily ex- tracted. Each little tumour will then require a separate operation, which is a far safer plan, than disturbing the part by long and repeated attempts to extract them all at once. ( Boyer , Traile dcs Mai. Chir. T. 4, p. 448.) The surgeon is also often obliged to make his incision at a particular point, be- cause at no other can the extraneous sub- stance be fixed. A case confirming all these, latter observations was lately published by- Ur. Clarke. (See Med. Chir. Trails. Vol. 5, p. 67.) In this instance, the operation was thrice performed upon the same knee-joint, with perfect success. Mr. Brodie also ex- tracted five loose cartilages, by three differ- ent operations, without any subsequent un- pleasant symptoms, although the patient ap- pears to have been previously subject to repeated attacks of severe inflammation of the joint. (. Pathological and Surg. Obs. v 299.) On the preceding subject some observa- tions and two successful operations have been lately published by Baron Larrey. (See Memoir es de Chir. Militaire , T.2,p. 421 , ty-c.) With the exception of a few wrong theories, he appears to have given a fair ac- count of the disease Hydrops Articuli signifies a collection of se - rous fluid in the capsular ligament of a joint. The knee is more subject, than other joints, to dropsical disease, which has been known, however, to affect the wrist, ankle, and shoulder joints. ( Boyer , Traitt des Mai Chir . T. 4 ,p. 456.) Mr. Russel adopted the opinion, that some cases of this kind are venereal, and others scrofulous ; but, he has not supported the doctrine on any solid foundation. Hydrops articuli generally arises from contusions, rheumatism, sprains, exposure to severe cold, the presence of extraneous cartilagi- nous bodies in the joint, and in general from any thing, which irritates the capsular ligament ; and, as already explained, it is a common attendant on inflammation of the synovial membrane ; the complaint also sometimes follows fevers ; but, in most in- stances, it is purely a local affection, quite independent of general debility. ( Boyer T. 4, p. 467.) Hydrops articuli presents itself in the form of a soft tumour ; circumscribed by the at tachments of the capsular ligament ; with- out change of colour in the skin ; accom- panied with a fluctuation ; it is indolent, and very little painful ; causing hardly any impediment to the motion of the joint ; yielding to the pressure of the finger, but not retaining any impression, as in cedema. The swelling does not occupy equally every side of the joint, being most conspicuous where the capsular ligament is loose and superficial. In the wrist it occurs at the anterior and posterior parts of the joint, but, especially, in the former situation, while it is scarcely perceptible at the sides. In the ankle, it is more apparent in front of the malleoli, than any where else ; and, in the shoulder, it does not surround the joint, but is almost always confined to the forepart of it, and can only be seen in the interspace between the deltoid and great pectoral mus- cles. In the knee joint, whichTs the common situation of hydrops articuli, the tumour does not occur behind the articulation ; but at the front and sides. Behind, the capsular ligament is too narrow to admit of being 160 JOINTS. much distended with the synovia ; while, in front, and laterally, it is broad, so that it can there yield considerably in proportion as the quantity of fluid increases. The swell- ing is at first i-ircumscribed by the attach- ments of the capsular ligament ; but, in consequence of the accumulation of fluid, it afterward exceeds these limits above, and spreads more or less upward between the thigh bone and the extensor muscles of the leg which are lifted up by it. Boyer has seen it reach to the upper third of the thigh. The swelling is irregular in shape : it is most prominent where the capsular ligament is wi e and loose, and it is in some measure di- vided longitudinally into two lateral portions, by the patella, the ligament of the patella, and t'he tendon of the extensor muscles of the leg, all which parts the synovia raises, and pushes forward, though in a much less degree than the capsular ligament. Of these lateral portions, the internal is broadest and most prominent, because the part of the capsule between the patella and edge of the inter- nal condyle being larger than that situated between the patella and edge of the exter- nal condyle, yields in a g eater degree to the distending fluid. The motions of the leg, which are generally little interrupted by this disease, make a difference in the shape and consistence of the swelling. In flexion, the tumour becomes harder, tenser, and broader and more prominent at the sides of the knee-pan, which is somewhat depressed by its ligament. In extension, the tumour is softer, and the fluctuation plainer. In order to feel distinctly the fluctuation, which is one of the best symptoms of the disease, the ends of two or three fingers should be placed on one side of the swell- ing, while the opposite side is to b ■ struck with the end of the middle finger of the other hand. The patella, being pushed forward, away from the articular pulle . , is very moveable, and, as it were, floating. When it is pressed backward, while the leg is extended, ii can be felt to move a certain ■ ay before it meets with the resistance of the articular puhey. And on the pressure being discontinued, it immediately separates from tins part again. By such symptoms, hydrops articuli may easily be distinguished f om other diseases of the joints, from tumours of the bursa mu- cosa under the extensor tendons of the leg; from ganglions in front of the knee-pan ; from rheumatism ; oedema, foe. The prognosis is most favourable, when the swelling is recent and small, and has been quick in its progress. On the contrary, when the tumour is of long standing and large; the effused fluid thick and viscid; and the synovial membrane thickened ; the removal of the fluid by absorption, and the restoration oi the parts to their natural state, will be more slow and difficult. The worst case is that which is complicated with dis- ease of the capsular ligament cartilages, md bones. The cure of the above-described dropsi- cal affection of the joints, depends upon the absorption of the effused fluid. And, when the case is combined with acute or chronic inflammation of the synovial membrane, th© treatment is the same as th t already recom- mended for those particular forms of dis- ease. When i- flammation subsides, the absorption of the fluid is sometimes altoge- ther spontaneous, and it may always be promoted, by mere friction, by rubbing the joint with camphorated mercurial ointment, and particularly, by the employment of blisters. The operation of a blister may be very materially assisted with a moderately tight bandage. Among other effectual melt ns of cure, we may enumerate frictions with flan- nel impregnated with the fumes of vinegar ; electricity ; and the exhibition of mercurial purgatives. When hydrops articuli occurs during the debdity, consequent to typhoid, and other fevers, the complaint can hardly be expected to get well, before the patient has regained some degree of strength. As, however, hydrops articuli is generally quite a local disease, Boyer contends, that it should be chiefly treated with topical re- medies ; and he sets down diuretics, sudo- rifics, hvdragogues, foe. as improper or in- efficient. (Op. cit. p. 467.) He is strongly in favour of repeated blisters, both for tho prevention and cure of the disease. Circumstances do not often justify making an opening into the joint : but, excessive distention, in some neglected cases, might certainly be an urgent reason for performing such an operation. Also, if the complaint should resist all other plans of treatment, and the irritation of the tumour greatly im- pair a week constitution, the practice would be justifiable. An interesting example of this kind is related by Mr. Latta. ( System of Surgery, Vol. 2, p. 490.) ft is best to make the opening in such a way, that the wound in the capsular liga- ment after the operation, will not remain directly opposite the wound in the skin. For this purpose, the integuments are to be pushed to one side, before the surgeon di- vides them. ( Encyclopedic Method. Part. Chir. Art. Hydropsie des Jointures.) The operation is not always successful, being sometimes followed by alarming symptoms, which either end fatally, or oc- casion a necessity for amputation. The fliiid also generally collects again, and as the synovial membrane is mostly thickened, it often inflames, and suppuration in the joint ensues. Hence, when hydrops articuli originates from rheumatism ; when it is re- cent, indolent, and not |. rge ; and when it does not seriously impair the functions of the joint ; Boyer recommends the operation not to be done. But, be sanctions its per- formance, when the disease is combined with extraneous cartilaginous bodies in the joint: or when it is very considerable, at- tended with severe pain, and impairment of the functions of the joint. (Op. cit. T. 4, p. 473.) Collections of Blood in Joints . — Most sys- tematic writers speak of this kind of case. JOINTS though it must be uncommon. Tumours about th£ joints, composed of blood, and Set down in numerous surgical works, as extravasations within the capsular ligaments are generally on the outside ot them. Certainly, if a collection of fluid were to take place in a joint immediately after a sprain, or contusion, and to continue to in- crease gradually for some time afterward, there would be reason to believe most of the contents of the tumour to be blood The production of an abscess, and the se- cretion of any fluid, would have required a longer time. VVere blood known to be undoubtedly effused in a large articulation, however, no man would be justified in making an open- ing for its discharge. No bad symptoms are likely to result from its mere presence, and the absorbents will, in the end, take it away. If an incision were made into the joint, the coagulated state of the extrava- sated blood would not allow such blood to be easily discharged. The best plan is to apply discutient re- medies ; a lotion of vinegar, spirits of wine, and muriate of ammonia for the first three or four days ; and afterw ard, friction with camphorated liniments may be safely adopt- ed. Mr. Hey relates a case, in which the knee- joint was wounded, and blood insinuated itself into the capsular ligament; yet though the occurrence could not be hindered, no harm resulted from the extravasation, which was absorbed, without having created the smallest inconvenience. ( Practical Obs. in Surgery, p. 354.) White Swelling . — The white swelling, or spina ventosa, as it was at one time not un- frequentlv called, in imitation of the Arabian writers, Khazes and Avicenna, has been a name indiscriminately applied to many dis- eases, which differ widely in their nature, curability, and treatment. Wiseman was the first who used the term Whin-S welling ; and if the expression did not confuse to- gether complaints of very different kinds, not much fault f ould be found w r ith it, because it unquestionably conveys an idea of one mark of some of these distempers, which is, that notwithstanding the increase of size in the joint, the skin is generally not inflamed, but retains its natural colour. (Pott.) The name, therefore, appears objection- able, only inasmuch, as it has tended to pre- vent the introduction of a sufficient number of well-founded and net.e>sary distinctions. Systematic writers have generally been con- tent with a distinction into two kinds, viz. rheumatic , and scrofulous. The last species of the disease they also distinguish into such tumours, as primarily affect the bones, and then the ligaments and soft parts ; and into other cases, in w'hich the cartilage*, ligaments, and soft parts be- come diseased before there is any morbid affection of the hones. Mr. Brodie has endeavoured to form a more correct classification of the different complaints, to which the term white-swelling is applied ; and his descriptions are valuable, because confirmed by extensive observation, and numerous dissections. With respect to the disease beginning in the ligaments, if the capsular ligaments be put out of considera- tion, it is, as this gentleman observes, a rare occurrence, and he has never met with a case, in which the fact was ptoved by dis- section. (Pathol, and Surgical Obs. p. 7.) 1. Tiie first case is mtiaimnalion ol the synovial membrane, as described in the fore- going pages, especially that torrn ot the dis- ease which often arises from cold, and con- stitutes the disease formerly often termed a rheumatic w hite swelling. 2. Another form ot disease, ordinarily comprised under the general name ol white- swelling, has been particularly described by Mr. Brodie : the disease originates in the synovial membrane, which loses its natural organization, and becomes converted into a thick, pulpy substance, of a light brown, and sometimes ot a reddish brow n colour, inter- sected by white membranous lines, and from 1-4 to 1-2 ot an inch, or even more than an inch in thickness. As this disease advances, it involves ail the parts of which the joint is composed, producing ulceration of ibe car- tilages, caries ot the bones, wasting ot the ligaments, and abscesses in different places. The complaint has invariably proved slow in its progress, and sometimes has remained nearly in an indolent state for many months, or even for one or two years ; but (says Mr. Brodie) I have never met with an instance, in which a real amendment was produced ; much less have I known any in which a cure was effected.’ (bee Medico- Chir. Trans . Vol. 4, p. 220, f the disorder being preceded by any inflammatory action in one part or the other, and the inflammation, which afterward lakes place, appears rather to be theattendant upon, than thee us« of ihe ulcerative process. One striking peculiarity ot ulceration of the articular cartila. es is, that ihe process may lake place without the formaiion of pus; for the disease often pro- ceeds so far as to cause caries of the bones, and y et no purulent matter is found within the joint. (See Brodie s Pathol, and Surgi- cal Obs. tyc. p. 102.) The investigations of the same author dispose him to believe, that a conversion of these cartilages into a soft fibrous structure, is a frequent .hough, not constant forerunner of ulceration. {P. 105.) When the ulceration of the cartilage occurs in the superficial joiuts, it constitutes one of the diseases which have been known by the name of white-swelling. From cases which Mr. Brodie has met with, he is led to con- clude, that when it takes place in the hip, it is this disease, which has been variously designated by writers, the “ morbus coxariusf the “ Disease of the Hip,” the “Scrofulous Hip,” the Scrofulous Caries of the Hip Joint.” At least, says Mr. Brodie, it is to this disease, that these names have been princi- pally applied, though probably other morbid affections have been occasionally confounded with it. {Med. Chir. Trans. Vol. 4,j?.236.) The ulceration of the articular cartilages takes place as a primary disease, chiefly in children, or adults under the middle age. “ Ot sixty-eight persons affected with this disease, fifty-six (according to Mr.Brodie)were under thirty years of age : the youngest was an infant of about twelve months the old- est was a woman of sixty. As the knee is more frequently affected by inflammation of the synovial membrane, so is the hip more liable, than other joints, to the ulceration of tue cartilaginous surfaces. In general tne disease is confined to a single joint ; but it is not very unusual to find two or three joints affected in the same individual, either at the same time, or in succession. Some- times the patient traces the beginning of his symptoms to a local injury, or to his having been exposed to cold ; but for the most part , no cause can be assigned for the complaint.” (see Med. Chir. Trans. Vol.6,p. 319.) The symptoms of the disease of the hip- joint will be described in the ensuing section, and we shall here confine our remarks to the symptoms characterizing ulceration of the cariilages of ihe knee, as pointed out by Mr. Brodie. ihey differ from those of inflam- mation ot the synovial membrane, by the pain being slight in the beginning, and gra dually becoming very intense, which is the reverse of what happens in the latter affec- tion. The pain in the commencement is also unattended witu any evident swelling, w Inch never comes on in less than four or five weeks, and often not till after several months. It is not to be inferred, however, that every slight pain of thp joint, unaccom- panied with swelling, must of course arise from ulceration of the cartilages. But, says Mr. Brodie, when the pain continues to in- crease, and at last is very severe ; when it is aggravated by the motion of the bones on each other, and when, after a time, a slight tumefaction <>t the joint takes place, we may conclude that the disease consists in such ulceration. The swelling arises from a slight inflammation of the cellular membrane on the outside of the joint : it has the form of the articulating ends of the bones ; and for the most part it appears greater than it really is, in consequence of the muscles being wasted. No fluctuation is perceptible, as where the synovial membrane is inflamed ; nor is there the peculiar elasticity, which exists where the synovial membrane has un- dergone a morbid alteration ot its structure. Ml* Brodie has explained, however, that JOINTS. 153 in some cases, the swelling has a different shape, and communicates the feel of a lluc- tuation. This happens when inflammation of the synovial membrane, attended with a collection of the synovia of the joint, or abscesses in the surrounding soft parts, or in the articulation itself, occur as secondary diseases. When there has been considerable destruction of the soft parts from abscesses and ulceration, the head of the tibia may become dislocated and drawn towards the ham. (See Med. Chir. Trans. Vol. 6, p. 326, 4^0 4. I shall pass over ulceration of the syno- vial membrane, which Mr. Biodie considers in a separate section, and now proceed to scrofulous white-swelling. In the scrofu- lous disease of the joints, the bones are pri- marily affected, in consequence of which, ulceration takes place in the cartilages cover- ing their articular extremities. The cartilages being ulcerated, the subsequent progress of the disease (says Mr. Brndie) is the same as where this ulceration takes place in the first instance. ( Medico- Chir . Trans. Vol. 4, p. 266.) By Mr. Lloyd, scrofulous white swellings are divided into three stages; the first being that in which the affection is confined to the bone ; the second, that in which the exter- nal parts become thickened and swelled ; and the third being what he names the sup- purative stage, attended with ulceration of the cartilages, inflammation of the synovial membrane, and abscesses. (On Scrofula, p. 321.) It was formerly a common notion, that in white-swellings, the heads of the bones were always enlarged. Mr. Russel, I believe, is the first writer who expressed an opposite sentiment, and he distinctly declares, that he had never heard , nor known of an in- stance in which the tibia was enlarged from an attack of white-swelling. (P. 37.) The inac- curacy of the opinion was afterward pointed out by Mr. Lawrence, to the late Mr. Crovv- ther, and the subject was mentioned in the earliest edition of the li First Lines of the Practice of Surgery.” Deceived by the feel of many diseased ioints, and influenced by general opinion, I once supposed, that there was generally a regular expansion of the heads of scrofu- lous bones. But excepting an . occasional enlargement, which arises from spiculae of bony matter, deposited on the outside of the tibia, ulna, &c. and which alteration cannot be called an expansion of those bones, I never until lately saw the head of a bone enlarged, in consequence of the disease known by the name of white-swelling. I was formerly much in the habit of inspecting the state of the numerous diseased joints,. which were every year amputated at St. Bartholo- mew’s Hospital, and though I was long at- tentive to this point, my searches after a really enlarged scrofulous bone always proved in vain. Nor was there at that peri- od any specimen of an expanded head of a scrofulous bone in Mr. Abernetby’s museum. Within the last few years, however, a speci- Vo r . u * ' ' 20 men of an enlargement of the upper head of the ulna has been found, and it was some time ago shown to me. by Mr. Stanley. My friend, Mr. Langstaflf, is said to have in his possession a knee-joint, in which the femur and tibia are much expanded, lt the external laminae of the bones not being thicker than when the bones are of their natural size, and the caneelli healthy, though of rather greater solidity than natural. (Lloyd on Scrofula, p. 148.) However, this last form of disease evidently does not resemble the common scrofulous affection of the heads of the bones. I may add, that Mr. Wilson, whose dissec- tions have beer, very numerous, concurs with the best modern writers, concerning the rari- ty of an actual expansion of the .substance of the heads of (he bones. (On the Skele- ton, fo. p. 336.) I have also heard of a few other instances in which the heads of the bones were actually enlarged in cases of white-swelling. However, I believe the occurrence is far from being usual, and doubts may yet be entertained, whether such enlargement is combined with the fol- lowing alteration of structure. The change which the head of the tibia undergoes in many cases, is first a partial absorption of the phosphate of lime throughout ilstexturej while at first a transparent fluid, and after- ward a yellow cheesy substance are deposit- ed in the caneelli. In a more advanced s action in diseased parts. These applications can obviously only act upon the principle of counter irritation, and they have not been here recommended particularly for white- swellings, because, it seems to me, .that whenever some good might be derived from their employment, much more benefit might always be obtained from blisters and issues. This sentiment is confirmed by ex- perience, and we must, therefore, impute a great degree of efficacy to the maintenance of a purulent discharge from the vicinity of the diseased part. Though my own observations have led me to think issues and blisters as efficient as any means hitherto devised for stopping the progress of scrofulous disease of the heads of the bones, l am far from meaning to say, that sucli disease can generally be stopped by these or any other remedies, local or general. Mr. Brodie has seldom known any benefit derived from blisters or stimulating liniments; nor has he seen the same degree of good produced by issues in scrofulous cases, as in examples of primary ulceration of the cartilages. Cold evnpo rating lotions in the early stage of the coir JOINTS. plaint ; peiTect quietude of the joint ; atten- tion to the patient’s health ; and riding in a carriage in the fresh air ; are the means which this gentleman particularly recom- mends in scrofulous diseases ot the joints. During the formation of abscesses, he ap- proves of fomentations and poultices. {Pa- thol. Ohs. p. 242.) We have noticed the efficacy of friction in exciting the action of the absorbents, by which the thickened state of parts around the affected joint may be considerably less- ened, and, on this principle, the utility of dry rubbing arises. We have now to notice the method of producing the same effect by pressure, a plan which yet seems to merit a more extensive trial. I have seen in St. Bartholomew’s Hospital, a few cases in which the swelling of the joints was mate- riaPy diminished, by encircling the morbid articulations with strips of adhesive plaster, applied with moderate tightness. A somewhat similar plan, though its mo- dus operandi is differently accounted for, appears also to have been tried in France. 11 J’ai dans quelques occasions (says Ri- cberand) obtenu les plus grands avantages de ^application d’uri taffetas eire autour de l’articulation tumefiee. On coupe un mor- ceau de cotte etoffe, assez large pour enve- lopper la totalite de la tumeur ; on enduit les bords d’une gomme dissoute. dans le vinaigre, et susceptible de la faire adherer intimement h la peau ; on l’applique en- suite de maniere que toute 1’acces soit inter- dit k Pair entre lui et les teguments. Lors- qu’au bout de quelques jours on leve cet appareil, on trouve la peau humide, ramollie par l’humeur de la transpiration condens6e en goutelettes a la surface interieure du taffetas. Dans ce procede, on fetablit un espece de bain de vapeur autour de l’articu- lation malade.” (Nosogr. Chir. T. 3 ,p 175, Edit. 2.) My friend, the late Mr. Clement Wilson Cruttwell, of Bath, sent me a very excel- lent case, illustrative of the efficacy of treatment by pressure. He remarks that, “ After cupping the part, and endeavouring to quiet the inflammation, I used blisters ; but they excited such intolerable pain, and produced so great a degree of swelling and inflammation, that I was under the necessity of healing them immediately. After two months strict confinement to bed, and the use of leeches and refrigerant washes, the inflammation having again subsided, and the pain being removed, I again ventured to apply one small blister, and again a similar attack of pain, swelling, and inflam- mation was produced. The joint became distended with fluid, of which it had always contained a large quantity, and the irritation of the constitution was excessive. By the liberal use of opium I once more succeeded in quieting the disturbance, and, convinced of the hazard of using blisters in such a sub- ject, I applied moderate pressure, by means of a roller, together with a wash, containing a large proportion of spirit, in order to keep up a constant evaporation. Th# skin, which was before much inflamed, and hard, has be come natural and flaccid, the pain has cea sed,the swelling has diminished, and I have every prospect of effecting a cure, with the preservation of tolerably free motion in the joint.” Mr. Cruttwell, in a subsequent letter, in- formed ine, that this case got completely well by the treatment with pressure, and had remained so for upwards of six months under full and free exercise. This example dearly evinces the impro- priety of using blisters in certain constitu- tions. In some remarks, annexed to the above case, Mq. Cruttwell expresses his con- viction, that absolute rest, cold applications, and pressure, would succeed in very many cases, without local counter irritation. Pressure, he adds, succeeds best when fluid is effused, and the disease is indolent ; but he is convinced that it may be used with advantage in later stages, when abscesses have formed, and sinuses already exist ; and he reminds me how very serviceable con- tinued pressure is to the scrofulous finger- joints of children. The good effects of pressure in scrofulous cases are confirmed by the observations of Mr. Brodie: when, says he, after several abscesses have taken place, the tendency to suppuration has ceased, and the swollen joint has become diminished, anchylosis is probably disposed to take place. At this period, pressure, by means of strips of linen . spread with soap-cerate, or some other mo- derately adhesive plaster, and applied in a circular manner round the limb, will be productive of benefit. ( Pathol . and Sur z Obs. p. 243.) When the knee is affected, the limb 1ms a tendency to become permanently bent It must undoubtedly be judicious to pre vent this position, by means of splints, which will also serve to prevent all motion of the diseased joint, an object of the verv highest importance. Were the disease to end in anchylosis, the advantage of having the limb in a state of extension need scarcely be mentioned. In cases which commence in the cancel- lous structure of the heads of the bones, it seems rational to combine, with the local treatment, the employment of such internal remedies as have been known to do good in other scrofulous diseases. “ It is to be sup- posed, (as Mr. Brodie observes) that the air of a crowded city must be more or less unfavourable ; and that a residence on the seacoast is likely to be more beneficial than a residence in the country elsewhere. The patient should live on a nourishing, but plain diet ; he should be in the open air in summer, as much as he can, without exer- cising the joint. His mode of life should, in all respects, be regular and uniform, " Mr. Brodie has found more benefit derived from the long use of steel medicines than any others, suspending their use, however, and substituting the mineral acids for them, when the formation of abscesses excites febrile action. With such means, in child- ren, he combines Ihe occasional exhibition of mercurial purgati ves. ( Pathol . Obs. p.245.) In a work, whicfai Mr. Lloyd has just pub- lished, it is assumed as a fact, that, in scro- fula, there always is more or less disorder of the functions of the digestive organs, and primarily of no other important function. Hence, the regulation of diet, the state of the bowels, and the hepatic secretions, is with this geritlema n a principal object ; and, with the latter views, he employs, after Mr. Abernethy’s plan, five grains of the blue pill every night, and half a pint of decoct, sars. twice a day, with opening medicines, if necessary, to procure regular daily evacuations. When acidity of the stomach is present, he gives soda, and, when the stomach is weak, cinchona, steel, and mineral acid<;. (On Scrofula, p. 37, «!pc.) However, no doubt can be entertain- ed, that these means, like many others, have no specific power over scrofulous diseases, and, like sea-air and sea-bathing, only answer by sometimes improving the state of the constitution. In the local treatment of scrofulous joints, Mr. Lloyd commends quietude of the limb, which is to Jbe confi- ned in a sling, or im splints, the occasional resistance of inflammatory action by leeches, and a diminution of temperature ; poul- tices when abscesses form ; opening such collections of matter early; and, after all irritation has ceased, issues, setons, blisters, or the antimoniaj ointment ; or compres- sion upon Mr. Baynton’s plan. (P. 152, fyc.) With respect to opening these ab- scesses early, Mr. Lloyd differs from many excellent surgeons, especially Dr. Albers, who distinctly states, that it is generally best to allow' them to burst of themselves. On this subject, however, great diversity of opinion prevails, and Langenbeck is among the advocates for making an early opening. (Bibl. B. 2, p. 39.) Hectic symptoms are those which we commonly have to palliate in these cases. When the appetite is im- paired, and the stomach will bear bark, this medicine should be given with the aromatic confection. Above all internal remedies, opium claims the highest recommendation, as it at once tends to keep off and relieve a debilitating diarrhoea, which too frequently prevails, at the same time that it alleviates pain and procures deep. The objection, made against its exhibition on the ground ihat it increases perspiration, seems exceed- ingly frivolous, when the above important benefits are taken into consideration. Too often, however, the terrible disease of which we are now treating, baffles all human skill and judgment, and the unhappy patient’s health having declined to the lowest state, he is necessitated to submit to ampu- tation, as the only chance of preserving life. It has been explained in speaking of Amputa- tion, that the condition of the patient’s health, and not of the diseased joint, forms the principal reason for recurring to the severe operation of removing the limb. If the patient’s constitution be equal to a longer struggle, no man can pronounce that every prospect oi saving the limb is at an end. Many diseased joints, apparently in the most hopeless condition, frequently take a favour- able turn, and, after all, allow the limb to be saved. The proposal of cutting out diseased joints, has been considered in the article Amputation. Disease of the Hip-joint. — This complaint is very analogous in its nature to the white- swelling of other articulations. In the same vay ns the latter disorder, it seems probable, that the disease of the hip has its varieties, some of which may be connected with scro f u!a, while others cannot be suspected to have any concern with it. Mr. Brodie’s investigations lead him to believe, however, that ihe disease is of that nature, in which the first change is disease and ulceration of the cartilages. The present complaint is most frequently seen in children under the age of fourteen ; but, no age, no sex, no rank, nor condition of 'life is exempt from the possibility of being afflicted, so that though children form a large proportion of those subjects, who are attacked ; yet the number of adults, and even of old persons, is considerable. The approach of the disease of the hip- joint is much more insidious, than that of a white-swelling. Some degree of pain always precedes the latter affection ; but, the only forerunner of the former is frequently a slight weakness, and limping of the affected limb. These trivial symptoms are very often not sufficiently urgent to excite much notice, and, when observed by superficial practition ers, are commonly neither understood, nor treated according to the dictates of surgical science. As there is, also, sometimes an uneasiness in the knee, w'hen the hip is affected, careless practitioners frequently mistake the seat of disease, and I have man) times seen patients, on their entrance into an hospital, having a poultice on their knee, while the wrong state of the hip was not at all suspected. This mistake is extremely detrimental to the patient, not on account of any bad effect, resulting from the applications so employed ; but, because it is only in the incipient period of the complaint, that a favourable prognosis can be made. In this stage of the disease, mere rest and repeated topical bleeding, will do more good in the course of a fortnight, than large painful issues will afterward generally accomplish in the long space of a twelvemonth. The symptoms of the disease of the hip- joint, when only looked for in the situation of that articulation, arc not very obvious to the surgical examiner. Though, in some instances, the attention of the surgeon is soon called to the right situation of the disease, by the existence of a fixed pain behind the trochanter major ; yet, it is too often the case, that mere pain about an articulation, entirely destitute of visible en largcment and external alteration ot colour, is quite disregarded, as a complaint of no importance in young subjects, and as a TO or*' JOINTS. 161 rheumatic, or gouty affection, in adults. Patients frequently complain of their most painful sensations being in the groin, and all accurate observers have remarked, that, in the hip disease, the pain is not confined to the real seat of disease, but shoots down the limb, in the course of the vastus exlernus muscle to the knee. The pain, says Mr. Brodie, is at first trifling, and only occasional ; but, it after- ward becomes severe and constant. It re- sembles a good deal the pain of rheumatism, since it often has no certain seat. As the disease advances, the pain becomes exceed- ingly severe, particularly at night, when the patient is continually roused from his sleep by painful startings of the limb. Sometimes he experiences a degree of relief in a parti- cular position of the joint, and no other. As the pain increases in intensity, it becomes more fixed. In the greater number of in- stances, it is referred both to the hip and knee, and the pain in the latter joint is gene- rally the most severe. At other times, there is pain in the knee, and none in the hip. A boy, in St. George’s hospital, complained of pain in the inside of the thigh near the middle ; and another patient referred the pain to the sole of the foot. Wherever the pain is situated, it is aggravated by the motion of the joint, and especially by what- ever occasions pressure of the ulcerated cartilaginous surfaces against each other. (Brodie's Pathol. Obs. p. 139.) The early symptoms of disease in the hip- joint are only strongly delineated to such practitioners, as have acquired the necessary information relative to this part of surge- ry, from careful study and extensive experi- ence. We shall next trace those characters of the present disease, which serve to denote its existence. It is a curious circumstance, that when the functions of a limb are obstructed by dis- ease, the bulk of the member generally diminishes, and the muscles become emacia- ted. Nearly as soon as the least degree of lameness can be perceived, the leg and thigh have actually wasted, and their circumfer- ence has diminished If the surgeon make pressure on the front of the joint, a little on the outside of the femoral artery, after it has descended below the os pubis, great pain will be experienced. “ Soon after the commencement of the complaint, (as Mr. Brodie remarks,) the hip- joint is found to be tender, whenever pres- sure is made on it either before or behind. The absorbent glands become enlarged, and occasionally there is a slight degree of gene- ral tumefaction in the groin.” The same gentleman has also adverted to the curious circumstance of there being in some cases a tenderness of the parts, to which, though not diseased themselves, the pain is referred from sympathy with the disease of the hip. This occurrence he has observed in the knee several times, and in one instance in the course of the peroriaeal nerve. He has also seen a slight degree of puffv swelling of the Vol. II. ’ 21 knee in a case, in which pain was referred to this joint, in consequence of disease of the hip. (P. 142, 143.) The limping of the patient is a clear proof, that something about the limb is wrong, and, if such limping cannot be imputed to disea- sed vertebrae, or some recent accident, and if, at the same time, the above-mentioned emaciation of the limb exists, there is great cause to suspect, that the hip is diseased, particularly when the pain is augmented by pressing the tront of the acetabulum. Diseased vertebrae, perhaps, always pro- duce paralytic affection of both legs at once, and they do not cause painful sensations about the knee, as the hip disease does. The increased length of the liinb, a symp- tom that has been noticed by all practition- ers since De Haen, is a very remarkable and curious occurrence, in tue early stage of the present disease. This symptom is easily de- tected by a comparison of the condyles of the os femoris, the trochanter major, and malleoli, of the diseased limb, with those parts of the opposite member, taking care that ihe patient’s pelvis is evenly situated. The thing is the more striking, as the in- creased length of the member is frequently as much as four inches. The rationale of this fact, John Hunter used to explain by the diseased side of the pelvis becoming lower than the other. (Croivther, p. 266.) The same thing bad also been noticed by Falconer, (On fschias, p. 9) long before the period, when Mr. CrowtUer printed his se- cond edition. It is easy (says Mr. Brodie,) to understand how the crista of one ilium becomes visibly depressed below the level of the other, when the position is remembered, in which the patient places himself when he stands erect. u He supports the weight of his body upon the sound limb, the hip and knee of which are in consequence maintained in the state of extension. At the same time, the oppo- site limb is inclined forward, and the foot on the side of the disease is placed on the ground considerably anterior to the other, not for the purpose of supporting the super- incumbent weight, but for that of keeping the person steady, and preserving the equi- librium. Of course, this cannot be done, without the pelvis on the same side being depressed. The inclination of the pelvis is necessarily attended with a lateral curvature of the spine, and hence one shoulder is higher than the other, and the whole figure in some degree distorted.” ( Pathol . Obs. p. 146.) These effects, says Mr. Brodie, are in general all removed by the patient’s lying in bed a few weeks, except when the deformity has continued a long time in a young growing subject. In justice to the memory of the late res- pected Dr. Albers, of Bremen, I ought here to mention, that he appears in his work on Coxalgia, to have firs! pointed out the de- formity of the spine in this disease, and the reason of such change, the tenor of his ob- servations upon this point agreeing with those subsequently made bv Mr. Brodie JOINTS. m An appearance of elongation of the limb is not exclusively confined to the early stage of the morbus coxarius : it may attend other 4 eases. I remember seeing in one of the wards of St. Bartholomew’s Hospital, a little girl, with a diseased knee, whose pelvis was considerably distorted in this manner, so that the limb of the same side appeared much elongated Her hip- joint was quite Sound. This case was pointed out to Mr. Lawrence and myself by Mr. Cother, of Gloucester. Vo!pi, Albers, and several other foreign vrritex’s, point out the fact, that the early stage of this disease is sometimes attended with an appearance of elongation, sometimes with that of a shortening of the limb. An explanation of the circumstance is given by Mr Brodie, as follows : “ In a few cases, where the patient is in the erect position, it may be observed, that the foot, which be- longs to the affected limb, is not inclined more forward than the other, but the toes only are in contact with the ground, and the heel raised, at the same time that the hip and knee ave a little bent. This answers to the patient the same purpose of enabling him to throw the weight of his body on the other foot ; but it produces an inclination of the pelvis in the opposite direction. The crista of the ilium is higher than natural, and there is an apparent shortening, instead of elonga- tion of the limb on the side of the disease.” ( Pathol . and Surg. Obs. p. 147.) Mr. Ford has very accurately called the attention of surgeons to the alteration, with respect to the natural fulness and convexity of the nates, that part appearing flattened, which is usually most prominent. I he glu- tasus raagnus becomes emaciated, and its edge no longer forms so bold a line, as it na- turally does at the upper and back part of the thigh, in the sound state of the limb. Although this symptom, in combination with others, is of importance to be attended to, it has been explained by Mr. Brodie, that {C it is not in itself to be regarded , as a certain diagnostic mark of disease in the hip ; since, in its early stage, this symptom is wanting ; and it is met with in other diseases, in which the muscles in the neighbourhood of the hip are not called into action, although the joint itself is unaffected. (See Medico- Chir. Trans. Vol. 6 , p. 322 .) Though there may be more pain about the knee than the hip, at some periods of the malady in its incipient state, yet the former articulation may be bent and extend- ed, without any increase of uneasiness ; but, the os femoris cannot be moved about, without putting the patient to immense tor- ture. The patient soon gets into the habit of bearing the weight of his body chiefly upon the opposite limb, while the thigh of the affected side is bent a little forward, that the ground may only be partially touched with the foot. This position is found to be the most comfortable, and every attempt to extend the limb occasions a*i increase of pfttn, This is the first stage of the disease, or that which is unaccompanied with sup pu- ration. The symptoms which precede the forma- tion of pus, vary in different cases, accord- ing as there is acute, or chronic inflamma- tion present. When the diseased joint is affected with acute inflammation, as gene- rally happens, the surrounding parts become tense and extremely painful ; the skin is even reddish ; and symptoms of inflamma- tory fever prevail. When the severity of the pain abates, a swelling occurs in the vicinity of the joint, and a pointing quickly follows. In this stage startings and catchings during sleep are said to be among the most certain signs of the formation of matter. “ The shortening of the limb,” says Mr. Brodie, “ which usually takes place in the advanced stage of the disease, is usually, but not always the precursor of abscess. The formation of matter is also indicated by an aggravation of the pain ; by more frequent spasms of the muscles, by a greater wasting of the whole limb, and by the circumstance of the thigh becoming bent forward, and being incapable of extension,” and by the pulse becoming quick, the tongue furred, and the whole system being in a state of pre- ternatural excitement. f \ The abscess usu- ally shows itself in the form of a large tu- mour over the vastus externus muscle ; some- times on the inside of the thigh, near the middle ; and occasionally two or three ab- scesses appear in different parts, and burst in succession.” ( Brodie's Pathol. Obs. p. 152.) We have noticed the commonly lengthen- ed -state of the limb, in the first periods of the hip disease. This condition is not of very long duration, and is sooner or later succeeded by a real shortening of the affect- ed member. The foot may be turned in- wards ; but, as Mr. Brodie observes, if left to itself, it is generally turned outwards. In other cases, the limb is shortened ; the thigh is bent forwards ; the toes are turned inwards, and do not admit of being turned outwards ; (Pathol. Obs.p. 148;) and all the symptoms of a luxation of the thigh upwards and out- wards may be observed, the head of the bone, indeed, being actually drawn into the external iliac fossa, and carried betwixt the os inno- minatum and glutaeus minimus, which is raised up by it. (See Richerand JYosogr. Chir. T. 3, p. 171, 172, Ed. 2.) When the retraction is very considerable, it arises from nothing less than an actual dis- location of the head of the thigh-bone, in consequence of the destruction of the car- tilages, ligaments, and articular cavity. This retraction sometimes comes on long before any suppuration takes place The head of the bone is sometimes dislocated, and the disease terminates in anchylosis, without any abscess whatever. However, if sup- puration has not taken place, Mr. Brodie be- lieves, it rarely happens, that the limb, after the cure, does not regain its natural degree of mobility. (See Med. Chir. Trans. Vol. 6, p. 325.) It is worthy of particular notice, that the JOINTS. 163 head of the hone is always luxated upwards and outwardB ; and the only exception to this observation, upon record, is a case re- lated by Cocchi, in which a spontaneous dis- location of the thigh-bone, as it is termed, happened upwards, forwards, and a little inwards. (See LeviilU, JYouvelle Doctrine Chir. T. 3. p. 695.) On a egalement vu la tete du femur luxee en dedans et en bas, et placee sur le trou obturateur, mais cette mode de deplacement consecutif, dans lequel le membre est alonge, est infiniment rare. (Richerand, JYosogr. Chir T 3, p. 172.) The hip disease generally induces hectic symptoms, after it has existed a certain time. In some subjects, such symptoms soon come on ; in others, the health remains unaffected a very considerable time. “ The health of the patient (says Mr. Bro- die) usully suffers, even before abscesses have formed, from the want of exercise pain, and particularly from the continued disturbance of his natural rest. I recollect no instance of an adult, in w hom abscesses had formed, and who did not ultimately sink exhausted by the hectic symptoms which these indu- ced. Children may recover in this ultimate stage of the disease ; but, seldom without a complete anchylosis of the joint.” (Med. Chir. Trans. Vol A i, loco cit.) When abscesses of the above description burst, they contir.ue, in general, to emit an unhealthy thin kind of matter for a long time afterward. With respect to the morbid anatomy of the disease in its incipient state, until lately little was known. A few years ago tw o dis- sections related by Mr. Ford were, perhaps, the only ones throwing light upon this point. In one, there was a tea-spoonful of matter in the cavity of the hip joint. The head of the thigh-bone was a little inflamed, tfce cap- sular ligament a little thickened, and the ligamentum teres united in its natural way to the acetabulum. The cartilage lining the cotyloid cavity was eroded in one place, with a small aperture, through which a probe might be passed, underneath the cartilage, into the internal surface of the os pubis on one side, and on the other, into the os iscliii ; the opposite, or external part of the os in- uominatum showing more appearance of disease, than the cotyloid cavity. In the other instance, the disease was more advan- ced. These examples are important, inas- much as they prove that what is commonly called the disease of the hip joint, primarily affects the cartilages, ligaments, and bones, and not the surrounding soft parts, as De Haen and some others would lead one to believe. As the disorder advances, the portions of the os ischium, os ilium, and os pubis, com- posing the acetabulum, together with the in- vesting cartilage, and synovial gland, are destroyed. The cartilage covering the head of the os femoris, the ligamentum teres, and capsule of the joint, suffer the same fate, and caries frequently affects not only the adjacent parts of the ossa innominata, but also the head and neck of the thigh- bone. The bones of the pelvis, however, are always more diseased than the thigh- bone, a fact which displays the absurdity of ever thinking of amputation in these cases. Mr. Ford observes, “In every case of dis ease of the hip joint, which has terminated fatally, I have remarked, that the os inno- minatum has been affected by the caries in a more extensive degree, than the thigh bone, itself’ (Observations on the Disease oj the H>p joint, p. 107.) Sometimes how ever, the head and neck of the thigh-bone are annihilated, as well as the acetabulum. Mr. Brodie has had opportunities of dis- secting some diseased hip joints both in the incipient and advanced stage of the com- plaint. From his observations, it appears ; 1st. That the disease commences w ith ulcera- tion of the cartilages, generally that of the acetabulum first, and that of the femur after- ward. 2. That the ulceration extends to the bones, which become carious ; the head of the femur diminishing in size, and the acetabulum becoming deeper and wider. 3. That an abscess forms in the joint, w hick after some time makes its w ay by ulceration, throng! i the synovial membrane and capsu- lar ligament, into the thigh and nates, or even through the bottom of the acetabulum into the pelvis. Mr. A. Cooper showed Mr. Bro- die two specimens, in which the abscess had burst into the rectum. 4. In consequence of the abscess, the synovial membrane and capsular ligament become inflamed and thickened. The muscles are altered in structure ; sinuses are formed in various parts, and, at last, all the soft parts are blended together in one confused mass, resembling the parietes of an ordinary abscess. (Brodie, in Medico-Chir.' Trans. Vol. 4,p. 246, 247.) Such are the beginning and progress of the ordinary disease of the hip joint; but, it is admitted by Mr. Brodie, that there are. other scrofulous cases, in which the mis- chief begins in the cancellous structure of the bones, and also other instances, which consist in chronic inflammation and abscesses of the soft parts in the neighbourhood of the hip. (Op. cit. Vol 6, p. 326.) External violence; lying down on the damp ground in summertime ; and all kinds of exposure to damp and cold; are the causes to which the disease, has sometimes been referred No doubt, scrofula has, frequently, some concern in its origin ; but, often, no rational cause is assignable for the complaint. Treatment of the disease of the Hip Joint. — The writings of Hippocrates, Celsus, C&- lius Aurelianus, Hi c. prove, that the ancients treated the present disease much in the same way, as it is treated by the moderns. Form- ing an eschar, and keeping the sore open ; topical bleeding ; cupping ; fomenting the part, &.c. were all proceedings adopted in the earliest periods ot surgery. Drs. Charlton, Oliver, and Falconer, have extolled Bath w ater, as a most efficacious application to diseased Jiip joints, previ«us to the suppura^ 164 joints; live stage. However, had not their accounts in children, and even in grown-up persons, been exaggerated, all patients of this kind when the complaint is recent, they agree in would long ago have flocked to Bath, and thinking blisters capable of affording com- the surgeons in other places would never plete relief. Mr. Brodie states, that in these have had further occasion to adopt a more cases they are more efficacious when kept painful mode of treatment. The plan pur- open with the savine ointment, than repeat- sued at Bath, is to put the patient in a warm edly applied. With respect to issues, he ac- bath, two or three times a week, for fifteen knowledges, that behind the great trochan- or twenty-five minutes. In the first stage of coxalgia, the late Dr. Albers, however, had a very high opinion of warm bathing, fomentations with decoctions of herbs, and of bathing in mineral waters and the sea. But, though he commenced the treatment with the frequent use of the warm hath, and continued the plan a long while, it is to be remarked, that he also com- bined with it an issue. After the patient had been in the bath a period not exceeding half an hour, he was taken out, and his w r holc body well rubbed with flannel. It appears to me, that one objection to this practice must be the considerable disturbance occa- sioned by moving the patient in this manner every morning ; for if it be true, that most of these diseases commence in the cartilages of the joint, all motion of the limb must be particularly injurious. In the early period of the disease, entire rest, the application of fomentations, and the employment of topical bleeding, parti- cularly cupping, are highly proper. Such practice, also, is invariably judicious, when- ever the case is attended with symptoms of acute inflammation. When the fomenta- tions are not applied, the lotio aquae lithar- gyri acetati may be used. This method of treatment ought never to be employed, unless manifest signs of active inflammation be present. When no such state exists, this plan can only be regarded as preventing the adoption of a more effica- cious one, and, therefore, censurable. “Where the cartilages of the hip are ul- cerated (says Mr. Brodie,) the patient should in the first instance, be confined to a couch, if not to his bed . and if the disease is far advanced, the limb should be supported by pillows properly disposed, so as to favour the production of an anchylosis, by allow- ing it to vary as little as possible from one position.’ (S ee Medico- Chir. Transs. Vol.6,p. 335.) Quibus diuturno dolore, says Hippocrates,, ischiadico vexalis roxa excidil , iis femur con- tabescit et claudicant , nisi urdntnr. Forming an eschar, or issue, is the most efficacious plan of treating the disease even now known. A caustic issue seems to me more beneficial than a blister. The depression, just behind and below the. trochanter major, is the situation in which surgeons usually make the issue, and ihe size of the eschar should be nearly as large as a crown-piece. It is generally necessary to keep the issue open a very long time. When the thigh-bone is dislocated, and the patient survives, the case mostly ends in anchylosis. For the cure of the disease ia adults, Mr- Brodie and Dr. Albers have also ex- pressed a preference to caustic issues ; but ter is the most convenient place for them ; but be believes that they have more effect, when made on the outside of the joint on the front edge of the tensor vaginae femoris muscle. Instead of keeping the issue open with beans, Mr. Brodie has found it a more effectual practice to rub the sore, two or three times a week, with the potassa fusa, or sulphate of copper. In particular cases, where the pain was very severe, this gen- tleman made a seton in the groin over the trunk of the anterior crural nerve, which plan, he says, affords quicker relief, though in the end it is less to be depended upon for a cure, than caustic issues. In Dr. Albers’s work, the great efficacy of issues and blisters in giving immediate relief to the severe pain in the knee, is illustra- ted by some valuable observations. He speaks also very favourably of the rnoxa, the employment of which he says is not very painful ; a remark, in which Langen- beck concurs. (See Bibl. B. 2, p. 27.) Dr. Albers, in the hectical stages, recommends opium as highly useful, especially when combined with musk, or camphor. The occurrence of suppuration makes a vast difference in the prognosis. “ The formation of even the smallest quantity of pus in the joint in cases of this disease, in the young person, considerably diminishes, and in the adult almost precludes the hope of ultimate recovery.” ( Brodie , in Medico - Chir. j£rnns. Vol. 6, p. 347.) This gentleman is no^much in favour of opening the ab- scesses early, at least before the joint has been kept for some time perfectly at rest. He has seen no ill consequences arise from the puncture of the lancet remaining open, and he has not found, that in cases of cari- ous joints, the method of evacuating the matter, recommended by Mr. Abernethy (see Lumbar Abscess,) is attended with any particular advantage. Mr. J. Burns, in the second vol. of his “ Dissertations on Inflammation,” p. 314, has recorded a remarkable instance, in which this joint was affected with that intractable and fatal distemper, the fungus hasmatodes. The case was at first, supposed to be the dis- ease, of which we have just been treating in the preceding columns. The limb seemed to be elongated, and issues »vere employed, without any material benefit. The upper part of the thigh swelled, while the lower wasted away. The patient lost ii is appetite, had a quick pulse, and passed sleepless nights. The part was rubbed with anodyne balsam arj,d laudanum given e lachrymal gland is subject to scirrhous enlargement, and, in cases of carcinoma of the eye, it is one of the parts in which a re- turn of the disease is apt to occur. Hence, it is now generally considered right to re- move, it as soon as the eyeball has been taken away. (See Eye.) Sometimes the gland is primarily affected, and Guerin removed one in the state of scirrhus, and so much enlarged, that the eye was entirely covered by it. This operation was performed with such dexterity, that the ex’ernal straight muscle was not at all injured. Mi . Travers has also removed a scirrhous and enlarged lachrymal gland. The vision of the eye had suffered considerably during the growth of the tu- mour. The only deformity after the opera- tion, was a slight prolapsus of the eyelid. 'This gentleman recommends operations of this kind to be always done, if possible, be- neath the eyelid. ( Synopsis , fyc. p. 22u les larmes re- fluent continuellement sur les joues, k t ravers les points lachrymaux: soit qu’en partie de- truites et ulcerees, res parois presentent une fistule, qui offre aux larmes un passage rontre nature, sans cesse entretenue par elles ; en sorte que ces deux htats, latumeur et la fistule, soot presque toujours des degres differeus d’une meme affection, et que le traiteraent qui convient k Tune repose sur les tnemes bases que celui indiquh dans I’autre.” (( Euv - res Chir. de Desault, T.2,p. 120.) It is evi- dent from the writings of Pott and Ware, that even these authors considered the ob- struction of the nasal duct, as the foundation of all the train of varied symptoms present- ed by the excreting lachrymal organs. “ An obstruction in the nasal duct is most fre- quently the primary and original cause of the complaint.” “ The seat of this disease is the same in almost every subject,” says Mr. Pott ( Obs . on the Fistula Lachrymalis ;) and Mr. Ware, in his observations on the same disease, sets out with the same assumption. Now, obstruction of the nasal duct is an oc- casional consequence merely of inflamma- tion of the excreting lachrymal organs ; in most of their diseases, obstruction of the 0 nasal duct has no part; and one might, with as much propriety, treat all the affections of the bladder and urethra, by the dilatation of the latter part, as treat all the diseases of the excreting lachrymal organs, by dilating the nasal duct. The false assumption in ques- tion has led to most erroneous treatment. For instance, in blennorrhcea of the sac, and in hernia of the sac. though in both these diseases the nasal duct is patent, the common treatment in this country is to open the sac by the knife, and thrust down a style, or some other instrument into the nose . thus destroying the organiza- tion of the parts which are affected merely with a gleety secretion in the one case, and with extreme relaxation in the other. Sup- pose (says the some critical writer) that some charlatan should make oath at the Man-ion-t louse, that hp had cured fiftv or a hundred cases of gonorrhoea by opening the urethra in the perinmum, and passing a bou- gie through that tube, from behind forwards, who would approve of such an operation ? Yet the laying open of the lachrymal sac, and thrusting a probe down into the nose, when the nasal duct is either perfectly pa- tent, oral the most, slightly tumid from inflam- mation, is neither less preposterous, nor less cruel. (See Quarterly Journ. of Foreign Medicine Vol. 1, p. 293.) Indeed, it is some- what surprising, that errors of this kind should have prevailed so long, particularly as expe- rience had taught Mr. Pott, that slight cases might be benefited by the simple employment of a vitriolic collyrium ; a fact which ought to have convinced him, that the disease did not always depend upon obstruction of the nasal duct. It is curious, therefore, that he did not fully see this mistake ; for, that he knew of these diseases having great va- riety, is evident from the following remark: As the state and circumstanc.es of this disease are really various, and differ very essentially from each other, the general custom of call- ing them all by the one name of fistula lach- rymalis is absurd.’* I believe, that one great cause of deception has been the fact, that, though laying open the lachrymal sac, and the introduction of instruments down the nasal duct, have been frequently practi- sed, when milder plans would have answer- ed every purpose, yet a cure has often fol- lowed the practice, and thus confirmed the supposition of relief having been effected by the removal of the imaginary obstruction in the nasal duct. Thus the late Mr. Rums- den, of St. Bartholomew’s, with whom I served my apprenticeship, always followed the common plan of passing a probe down the nasal duct, and letting the patient keep a piece of bougie, or a style, in the part for two or three months afterward; and I scarcely recollect an instance in whicb he failed to accomplish a cure, though I have no doubt that the same benefit might some- times have been obtained without any opera- tion at all. And a discerning practitioner should never forget that, if no permanent obstruction exist in the nasal duct, a cure will generally follow, on the subsidence of in- flammation, and a change taking place in the action of the parts, whether a probe, style, can- nula, bougie, or seton- be employed, or net. Erysipelas of the Parts covering the La- chrymal Sac . — Beer considers it highly ne- cessar> that this case should bediscriminated from infl ruination of the sac it- elf, which is otten but little affected, and this even when an abscess forms. Unless the true ; ature of the disease be comprehended, the surgeon is apt to suppose, that the matter is in the sac itself, and believes that, when he makes an opening, he is puncturing that receptacle, \vherea9 lie is in reality, merely dealing with a superficial abscess of the integuments. Nor, as Beer has observed, is the mistake free from ill consequences ; for, imagining LACHRYMAL ORGANS. KiS that the wound is made into the sac, the surgeon pokes about with his probe so long, that a good deal of unnecessary pain and in- flammation is produced. According to the same author, the case is not very frequent, and is mostly met within scrofulous subjects, who have had for a considerable time a blennorrhcea of the lachrymal sac. The in- flammation partakes of the usual characters of erysipelas, and commonly extends to the eyelids, particularly (tie upper one. The ab- sorption and conveyance of the tears into the lachrymal sac are interrupted, because the inflammation constantly fleets the la- chrymal ducts and papillae, the latter appear- ing considerably shrunk. When the inflam- mation spreads over the side of the face. Beer says there is usually a discharge ol thin mucus from the nose; anil when the affec- tion extends more deeply to the anterior por- tion of the lachrymal sac, as may easily hap- pen when 11 enough to enter one of the puncta, and by that means to furnish an opportunity of injecting a liquor into the sac and duct ; and with these two instruments he pretended to be able to cure the disease whenever it consisted in obstruc- tion merely, and the discharge was not much discoloured. “ The first of these, viz. the passage of a small probe through the puncta, ('says Mr. Pott) has a plausible appearance, but will, upon trial, be found very unequal to the task assigned ; the very small size of it, its necessary flexibility, and the very little resistance it is capable of making, are mani- fest deficiencies in the instrument ; the quick sensation in the lining of the sac and duct, and its diseased state, are great objections on the side of the parts, supposing that it was capable of answering any valuable end, which it most certainly is not.” {Poll.) It must be at once obvious, that Anel’s instruments were devised with the view of avoiding a puncture in the lachrymal sac ; but the principle has been strongly objected to by Beer, there being no comparison be- tween the inconveniences of a small open- ing made in the sac, and the injury done to rhe lachrymal puncta and canals by the long and repeated introduction of instruments through them, whereby their functions are likely to be for ever ruined, of which Beer has seen some sad examples. ( Lekrc , ^-c. B. 2, p. 169.) The next practice deserving notice, is that of Laforest, who used to introduce into the termination of the nasal duct in the nostril a probe, with* which he cleared away the ob- struction in the passage. He also introdu- ced into the same orifice a curved tube, which was left in the part three or four months, for the purpose of employing injec- tions. The method, however, was found not only troublesome and difficult, on account of the anatomical varieties to which the ter- mination of the nasal canal was liable, but also on account of the treatment, when practised, being subject to frequent failures. Following up the principles of Anel, another French surgeon, Mejean, dilated the nasal duct with a seton, which was drawn up into the lachrymal sac by means of a thread first introduced fro m the upper punc- tual lachrymaie. But it was soon discover- ed, that what was gained on one side, was lost on the other ; the lodgment of the thread in the lachrymal duct for several months, and the irritation of its orifice in changing the seton every day, not only causing inflammation of the punctum lachry- maie, but even such ulceration and cicatri- ces, as sometimes destroyed the functions of the parts. J. L. Petit, sensible of live inconveniences of Mejean’s practice, and disgusted with the barbarous imitation of the ancient! in cauter- izing th^ fistula, sac,, and os unguis, concei ved that, instead of these plans, or that of perforating the os unguis, as proposed by Woodiouse, it would be better to endeavour to restore the natural passage, by removing the obstruction in the nasal duct, which ob- struction Petit regarded as the cause of the disease. His method consisted in opening the lachrymal sac with a small bistoury, in- troducing through the wound, sac, and nasal duct a probe, down into the nostril, anil then using bougies for the dilatation of the passage. This method may be said to be the model of that which has been most ex- tensively followed even down to the present time. Pellier and Wathen recommended introducing a metahic tube down the ductus nasalis, and leaving it for a time in that situa- tion, with a view of preventing the duct from closing again ; and the use of a cannula is even now preferred by Dupuytren, the greatest surgeon of France. The desire of avoiding any puncture of the sac has influenced many practitioners besides Anel, and given rise to various inge- nious inventions. Thus, in 17S0, Sir William Blizard proposed, instead of injecting water, to introduce quicksilver through a small pipe, communicating with a long tube full of this fluid. I he specific gravity of the quicksilver, when the sa was distended with it, he believed would have more power than water propelled through a syringe, to remove the lachrymal obstruction. The late Mr Ware, after trying Sir Wil- liam Blizard’s plan, gave the preference to Anel’s syringe, with which he generally in- jected warm water, through the lower punc- tual lachrymaie, into the lachrymal sac, and put a finger over the superior puUCt »nf» m LACHRYMAL ORGANS. prevent the Quid from escaping through it. With his finger he also occasionally com- pressed the lachrymal sac, in order to assist in propelling the water down into the nose. Mr. Ware sometimes used the injection thrice a day, though, in general, much less frequently. (See Ware on the E pi for a.) 11 1 in general begin the treatment by in- jecting some warm water through the infe- rior punclum laebryrnale, and I repeat the operation four or five days in succession. If in this space of lime, none of the water pass through (he duct into the nose, and if the watering of the eye continue as trouble- some as it was before the injection was em- ployed, I usually open the angular vein, or direct a leech to be applied near the lach- rymal sac ; adding here a caution, that the leech be not suffered to fix on either of the eyelids, lest it produce an extravasation of blood in the adjacent cells. About the same time that blood is taken away in the neigh- bourhood of the eye, I usually vary the injection, and try the effects cither of a weak vitriolic, or anodyne lotion. In some instances also, when I have found it impos- sible, after several attempts, to inject any part of the liquid through the duct, I have introduced a golden probe, about the siae of a bristle, through the superior puncturn lachrymale, and, attending to the direction of the duct, have insinuated its extremity through the obstruction, and conveyed it fully into the nose; immediately after which I have found that a liquid, injected through the inferior puncturn, has passed without any difficulty ; and by repeating these ope- rations for a few successive days, I have at length established the freedom of t he pas- sage, and completed the cure. In other in- stances, I have recommenced a strongly stimulating sternutatory to he snuffed up the nose, about an hour before the time of the patient’s going to rest, which, by exciting a large discharge from the Schneiderian membrane, has sometimes also greatly con- tributed to open the obstruction in the nasal duct “ Cases occur very rarely which may not be relieved by some of the means above re- lated.” {Ware's Additional Remarks on the Epiphora. ) Wfrfen the discharge was fetid, Mr. Ware sometiipes found, that a vitriolic lotion in- jected into the sac, quickly corrected the quality of the matter. In a subsequent tract, Mr. Ware observes, that if, after “ about a week or ten days, there be not some perceptible advance to- wards a cure, or, if, from the long continu- ance of the obstruction, there be reason to fear, that it is too firmly fixed to yield to this easy mode of treatment, I do not hesitate to propose the operation which is now to be described. .The only persons, with respect to whom I entertain any doubts as to the propriety of this opinion, are infants. In such subjects, 1 always think it adviseable to postpone the operation, unless the symp- toms-be particularly urgent, until they are eigljX or nine years old. Yh t, FT ' * “ If the disease has not occasioned an aperture in the lachrymal sac, or if this aperture be not situated in a right line with the longitudinal direction of the nasal duct, a puncture should be made into the sac, at a small distance from the internal juncture of the pnlpebr®, and nearly in a line drawn horizontally from this juncture toward the nose, with a very narrow spear-pointed lancet. The bl unt end of a silver probe, of a size rather smaller than the probes, that are commonly used by surgeons, should then be introduced through the wound, and gently, but steadily, be pushed on in the direction of the nasal duct, with a force sufficient to overcome the obstruction in this canal, and until there is reason to believe, that it has freely entered into the cavity of the nose. The position of the probe, when thus intro- duced, will be nearly perpendicular ; its side will touch the upper edge of the orbit : and the space between its bulbous end in the- nose and the wound in the skin will usually be found, in a full-grown person, to be about an inch and a quarter, or an inch and three-eighths The probe is then to be withdrawn, and a silver style of a size nearly similar to that of the probe, but rather small - er, about an inch and three-eighths in length, with a Hat head like that of a nail, but. placed obliquely, that it may sit close on the skin, is to be introduced through the duct, in place of the probe, and to be left constantly in it. .For the first day or two after the style has been introduced, it is sometimes adviseable to wash the eye with a weak satur- nine lotion, in order to obviate any tendency to inflammation which may have been exci- ted by the operation ; but this in general is so slight, that l have rarely had occasion to use any application to remove it. The style should be withdrawn once every day for about a week, and afterward every second or third day. Some warm water should each time be injected through the duct into the nose, and the instrument he afterward replaced in the same manner as before. I formerly used to cover the head of the style with a piece of dyachylon plaster spread on black silk ; but have of late obviated the necessity for applying any plaster by black- ening the head of the style with sealing wax.” Mr Ware did not. on first trying this me- thod, expect any relief, till the style was left off. However, he found, that the watering of the eye ceased, as soon as the style was introduced, and the sight became proportion- ably more useful and strong. The wound, which Mr. Ware makes in the sac, when there is no suitable ulcerated aperture, is only just large enough to admit the end of the probe, or style ; and this soon becomes a fistulous orifice, through which the style may be passed without the least pain. In short, in about a week or ten days, the treatment becomes so easy, that the patient, or any friend, is fully competent to do what is necessary. It merely consists in withdrawing the style, two, or three times a week, occasionally injecting some warm 23 ns LACHRYMAL ORGANS. water, and then replacing the instrument as before. Some, finding no inconvenience from the style, and being afraid to leave it off, wear it for years; many others disuse it in about a month, or six weeks, and continue quite well. The ulcerations, sometimes existing over the lachrymal sac, commonly heal, as soon as the tears can pass down into the nose ; but Mr. Ware mentions two instances, in which such sores did not heal until a weak solution of the hydrargyrus rauriatus, and bark, were administered. (See Ware on the Fistula Lachrymalis.) Great as the recommendation of the fore- going practice is, as delivered by Mr. Ware, Mr. Travers is strongly disposed to doubt, whether any permanent benefit was ever derived from letting the style remain in the passage. When an abscess over the sac has been opened, this gentleman, instead of the introduction of a style into the ductus nasa- l’s, recommends simply the examination of the duct with a fine probe. “ if the probe passes without resistance into the nose, the ease requires no further operative treatment, the integument recovers its healthy condi- tion under an emollient application, the discharge gradually diminishes, and the wound heals. If, on the other hand, upon examination with the probe, introduced through the wound, into the sac, resistance is offered to its passage into the nose, no more favourable opportunity will be pre- sented for overcoming such resistance. This, therefore, should be accomplished, but to this the operative process should be limited, and the wound should be suffered to heal without further disturbance.” When there is what Mr Travers terms a stricture in the nasal duct, and the passage of the probe is more firmly resisted, he admits that some means must be employed for keeping the duct pervious, after it has been reopen- ed. He never interferes with the integu- ments, except in the case ol abscess disco- louring the skin, and threatening to produce a fistula ; and for the purpose of restoring the passage, he uses a set of silver probes, of about five inches long, of various sizes, flattened at one end, and. slightly bulbous at the point. When there is no obstruction, these, he says, may be introduced with perfect facility from either of the puncta lachrymalia into the nostril. lt If the punc- tual be constricted, it is readily entered, and dilated by a common pin ; and, upon with- drawing it, by one of the smaller probes. The direction and relative situation of the lachrymal ducts, the sac, and nasal canal, point out the proper course of the instru- ment. It is confirmed by its advance, with- out the employment of force, and the sensa- tion conveyed by the free and unincumbered motion of its point. Until the point is fairly within the sac, it is necessary to keep the eyelid gently stretched and slightly everted ; the upper lid being drawn a little upward toward the brow ; the lower, as much down- ward toward the zygoma. The point carried borne to the sac, and touching lightly its nasal side, the lids may be left at liberty, while a half circular motion is performed by the instrument ; the surgeon neither suffer- ing the point to recede, nor, on the other hand, allowing it to become entangled in the membrane. The probe now rests, in a perpendicular direction, upon the eyebrow, toward its inner angle, and, in this direction, it is to be gently depressed, until it strikes upon the lloor of the nostril, where its pre- sence is readily ascertained by a common probe passed beneath the inferior turbinated bone. The probe, of smallest dimensions, is of sufficient firmness to preserve its figure in its passage through the healthly duct, but it is too flexible to oppose any considerable obstruction. For the stricture of the lachry- mal ducts, it is of sufficient strength. Very many, cases of recent origin, and in which the stricture has no great degree of firmness, (Mr. Travers says) are completely cured by three or four introductions of the probe into the nostril, at intervals of one, or two days. I have seldom met with a stricture so firm as not to yield^to the full-sized probe.” When the resistance is not altogether removed, after this plan has been tried some' days, Mr. Travers introduces a style, having a small fiat head, a little sloped, through the pane- turn lachrymale into the nose, and leave it in the nasal duct for twenty-four hours. It worn longer, he says, that it causes ulcera- tion of the orifice. A day or two is to elapse, before the style is again introduced, which must now be passed through the other lach- rymal duct. On the intervening days, tepid water should be injected with Anel s syringe. (Synopsis of the Diseases of the Eye. p. 369, 370, 372, 374.) Thus, we see, that Mr. Travers’s practice bears a considerable resemblance to that of Anel, inasmuch as the sac is never opened, except when likely to ulcerate, and nearly every thing is done with probes and injec- tions, introduced through the lachrymal puncta and ducts. I wish that my views of the nature of these diseases, and of the parts concerned, would allow me to think the latter proceedings, in the ease of stricture of the nasal duct, as commendable as another part of Mr. Travers’s practice, where, in cases of slighter obstruction, he contents himself with opening the sac, clearing away the stoppage of the nasal duct with a probe, and healing up the wound, without leaving an> style, cannula, or seton in the passage. Where the obstruction is very slight, such practice must be judicious. But if, in other cases, it he deemed right for the prevention of a relapse, that the nasal duct should be either filled with some dilating instrument a certain time, or repeatedly probed, I am decidedly of opinion with Professor Beer, M. Nicod, &c. that the object of not making a small opening in the sac is attended with no advantage, at ali likely to counterbalance the mischief, which must be done to the lachrymal puncta and ducts, not only by the repeated introduction of probes and of syringes, but by the lodgment of the former in them for the space <»i twenty-four hour* LACHRYMAL ORGANS, m together. If there be an opening in the sac, its convenience iri permitting the easy use of a probe is generally acknowledged ; and, in order to gain this advantage, and avoid the evils, which are inseparable from taking too much liberty with the lachrymal puncta and ducts, surely a slight puncture in the sac, if there be no opening already , must be the most rational, simple, and successful practice. When the perviousness of the nasal duct cannot be restored by any use of the probe, and the obstructed part has a very elastic feel, is of inconsiderable extent, and near the termination of the duct in the nostril, Beer recommends a perforation to be made with a trocar-shaped probe, the point of which is to be covered with a bit of wax, in order that it may not hurt the parts in its passage downward. Some discharge of blood from the nose indicates, that the perfo- ration is made. The sharp-pointed probe is then to be withdrawn, a blunt one used for the purpose of dilating the passage, and, at length, the catgut, as already explained. (Beer, B.2,p. 181.) Supposing the nasal duct to be obliterated for a considerable part of its extent, by a firmer substance, what practice should then foe followed ? Ought the formation of an artificial passage to be attempted ? On this point, modern practitioners differ, but, as the expedients adopted for this purpose cannot be judged of previously to their description, it will be better in the first place briefly to notice them. As Mr. Pott has re- marked, the upper and hinder part of the lachrymal sac is firmly attached to the os unguis, a small, and very thin bone, just within the orbit, which bone is so situated, that, if it be by any means broken through, the two cavities of the nose and orbit com- municate with each other: consequently, the os unguis forms the partition Jaetween the hinder part of the lachrymal sac, and the upper part of the cavity of the nose ; and it is by making a breach in this partition, that the formation of an artificial passage has been attempted. In Mr. Pott’s time, the cautery had long been disused for ma- king an aperture in the os unguis, and vari- ous instruments were recommended for this object, such as a large strong probe, a kind of gimblet, a curved trocar, &sc. each of which, says this practical writer, if dexter- ously and properly applied, will do the business very well ; the one necessary cau- tion is, so to apply whatever instrument is used, that it may pierce through that part of the bone which ifes immediately behind the sacculus laArymalis, and not to push too far up into the nose, for fear of injuring the os spongiosum behind, while it breaks its way. Mr. Pott adds, that he himself has always used a curved troc&r, the point of which should be turned obliquely down- ward, from the angle of the eye, toward the inside of the nose. The accomplishment of the broach will be known by the discharge of blood from the nostril, and of air from the woalid, upon blowing the nose. Care -must be taken to apply the instrument to the part of the bone, anterior to the perpendicular ridge, which divides it. As soon as the perforation is made, a tent of lint should be introduced, of such size as to fill the aperture, and so long as to pass through it into the cavity of the nose : this should be permitted to remain in two, three, or four days, and afterward a fresh one should be passed every day, until the clean granulating appearance of the sore makes it probable, that the edges of the divided membrane are in the same state. The business now is to prevent the incarnation from closing the orifice ; for which purpose, the end of the tent may be moistened with diluted vitriolic acid, or a piece of lunar caustic, so included in a quill, as to leave little more than the'extremity naked, may at each dressing, or every other, or every third day, be* introduced ; by which the granulations will be repressed, and the open- ing maintained ; and when this has been done for some little time, a piece of bougie of proper size, or a leaden cannula, may be introduced instead of the tent; and leaving off all other dressings, the sore may be suf- fered to contract as much as the bougie will permit; which should be of such length, that one extremity of it may lie level with the skin in the corner of the eye, and the other be within the nose. The longer time the patient can be prevail- ed upon to wear the bougie, the more likely *> will be the continuance of the opening ; and when it is withdrawn, the external orifice should be covered only by a superficial pledget, or plaster, and suffered to heal un- der moderate pressure . (Pott.) After the perforating instrument was with- drawn, Mr. Ware recommended a nail- headed style, about an inch long, to be in- troduced through the aperture, in the same way in which it is introduced through the nasal duct, in cases in which the obstruction is not so great as to prevent its. passing in this direction ; and it may remain here with as much safety as in this last-mentioned in- stance, for as long a time as its continuance may be thought necessary to establish the freedom of the communication. Unfortunately for the scheme of making an artificial passage, nature was generally so busy, that sin 1 completely frustrated the aim of the surgeon by gradually filling up the new aperture again. Hence, some practi- tioners were not content with drilling a hole through the os unguis, but actually removed a portion of this bone either with the for- ceps proposed by Lamorier in 1729. (See M6m. de l’ Acad, des Sciences ,) or with cutting instruments, among which the most celebra- ted is the sharp-edged kind of cannula de- vised by Hunter. While this was being ap- plied, however, it was necessary to sup- port the os unguis with something passed up ihe nose, and a piece of horn was found to answer very well. Instead of these methods, Scarpa prefers destroying a portion of the os unguis with the actual cautery passed through a cannula; a practice; long ago ba- LACHRYMAL ORGANS. isv 11 i shed from good surgery, and most justly condemned by Richter. 1 do not feel it necessary to enter very particularly into the details of these methods of forming an artificial passage between the lachrymal sac and nostril, i have never seen a case, in which' 1 should have deemed such practice adviseable, and that the neces- sity for it must be rare must be inferred from what Mr. Travers has observed, viz. that he does not believe the perforation of the os un- guis ever really required it. (Synopsis, p. 379.) Beer’s remarks are also decidedly against the practice ; for, he states that, in order that the new opening may not be closed with lymph, it must be made too high up to serve the purpose of a diain, through which the mucus can descend by its own gravity. He has not met with a single case, either in his own practice, or among the patients whom he has had opportunities of seeing under other practitioners, where the per- foration of the os unguis had a successful result. On the contrary, in one healthy lad, the operation, which had been done by an experienced surgeon, was followed by the destruction of the nasai process of the up- per maxillary bone, one of the ossa nasi, and all the bones contributing to the forma- tion of the passage from the orbit into the nose. (See Lehre von den Augenkr. B. 2, p. 182) Hence, Beer thinks, that the pa- tient had better either submit to the incon- venience of being obliged to empty the dis- tended sac by pressure several times a day, or let the cavity of the sac be obliterated by means, calculated to excite the adhesive in- flammation in it. But, if the lachrymal puncta and ducts, as well as the nasal duct, are obliterated, Beer conceives that there is no alternative, because, if the cavity of the sac be left, tjie case, which he terms hydrops sacculi lachrymalis,will ensue, whenever the fistula is closed. Of Hernia and Hydrops of the Lachrymal Sac. — The diseases, described by Beer undgr these appellations, are not discriminated in this country, although they are characteri- zed by widely different symptoms, and re- quire opposite methods of treatment. In the case of hernia, or simple relaxation, the lachrymal sac forms a tumour, which never surpasses the size of a common horse-bean, the integuments are of their natural colour, the tumour is soft and yielding to pressure, by which the contents of the sac are readily dis- charged through the puncta, or nasal duct. Hydrops grows tothe s.ze oi a pigeon’s egg, is purplish from the beginning, very hard and in- capable of being emptied by t he strongest pressure. Hernia is cured by compression, and the application of astringents to the re- laxed parts ; hydrops requires the incision of the sac. In hernia, the nasal duct is natural; in hydrops, it and sometimes the puncta are obstructed. Stillicidium Lachrymarum. — According to Beer, the valuable treatise of Schmidt is the only work, in which the important practical distinction is drawn between stillicidium lachrymarum and epiphora; the immediate cause of the first complaint being some im- pediment to the passage of the tears from the lacus lachrymarum into the lachrymal sac ; while the other affection consists in a redundant and extraordinary secretion of the tears. The curable form of stillicidium, here to be noticed, arises from relaxation of the lachrymal puncta and canals, in conse- quence of previous inflammation of the parts. The puncta are widely open ; but in other respects, have quite a natural appear- ance. When touched with Anel’s probe, they do not contract, as in the healthy state. The tears, which from time to time fall over the cheek, are not in considerable quantity, only trickling from the inner can- thus by drops at intervals; and the nostril on the affected side is found to be rather drier than natural. Erysipelatous inflammation of the eyelids and parts over the lachrymal sac, and the purulent kinds of ophthalmy, frequently cause this sort of stillicidium. The latter cases indeed the more readily produce the disorder, inasmuch as the semilunar fold of the conjunctiva is relaxed and swelled, so as to push the puncta out of their right po- sition for the due performance of the absorp- tion of the tears, and obstruct this function more than Would be the case, if the dimi- nished action of those orifices and the la- chrymal ducts were the only thing con- cerned. Beer delivers an exceedingly favourable prognosis, observing, that the complaint often disappears of itself on the approach of warm dry weather, and may almost always be readily cured, by means of astringents. Among other remedies specified by this au- thor, 1 need only mention a solution of the sulphate of iron, to which a small quantity of camphorated spirit, or tincture of opium, has been added It is to be dropped out of a pen into the inner angle frequently in the course of the day, the patient lying upon his back for some time after each application, so as to let the medicine have more effect upon the parts (See Lehre von den Au * genfer. B. 2, p. 41 — 43.) Mr. Travers mentions a constricted state of the lachrymal puncta and canals, which is curable by the introduction of a small probe. ( Synopsis , fyc. p. 366.) All moden. write s agree, that the obliterated puncta and canals can never be restored. (See Memoires de I'Academie de Chirurgie, T. 5, Edit. 12 mo. in which are several essays on fistula lachrymalts viz. one by M. Bordenavc, entitled, “ Examen des (inflexions critiques de M. j\k>linelli, inve- rses dans les MSmovres de l i nsiimt de Bolvgnc , contre le Mcmoire de M. Petit, sur la Fist ale Lachrymale, insure parmi ceux de l' Acad. Hoy • ale aes Sciences de Paris. Annie 1734. Another * essay by M. de la Forest, styled u JVouvcllc Me - | thodc de Iraitcr les Maladies du Sac Lack - ryrnal, nominees commandment Fislults Lack- ry mules .” A third by M. Louis , called “ Be- if flexions sur V Operation de laflstuU Lachry- male." O. E. Stahl , Programma da Fistula LAC* lAfe Lachrymali, Halve, 1702'. J. C. Scholunger, J9e Fistula Lachrymali , Basil, 1730. D. Metzger, Curationum Chir. quce ad Fistulam Lachrymalem sive usque J'uere adliibitee , Hislo- ria Critica, 8 vo. Monarferii , 1772. P. Qucestio, <^c. An fistula-, lachrymali cau- terium actuale? Paris , 1738. J. L PefiJ, Tra/te des Mai. Chir. T. \\,p. 289, fyc. 8vo. Paris, 1774. M. A Magnabal. De Morbis Viarum Lachrymalium, ac pracipue de fistula lachrymali, Monlp. 1765. A. Berlrandi, Traite des Jpdrations, p. 297, 8 vo. Paris, 1784. Ariel has described his plan of treat- ment in various icorks : Observation sivgu- licre sur la fistule lacrymale , dans laquelle I on apprendra la methodt de la guerir radical e- ment .” Turin, 1713) in 4 to. u Nouvelle Mtihode de gu6rir les fistules lacry males." Turin, 1713, in4to. u Suite de la JYouvelle Methode," fyc. ibid. 1714 , in 4 to. “ Disst r- lation sur la nouvelle. d6couverte de I’hydropisie du conduit lacrymat ," Paris, 1716, in 12 mo. And , lastly , Anti has published in the M6m. de 1'Acad. des Sciences, annee 1713, “ Pricis de sa nouvelle mamtre de gudrir les fistules lacrymales." Me jean in Mdm. de VAcad. de Chir . T. 2, p. Iy3, 4to. Palucci, Methodus curanda fistulce lachrymalis, l 'indob. 1762; a tube preferred. Sabatier, Midecine Opdra- foire, T. 2, Ed. 2. Richter's Anfanccsgriinde dtr fVundarzneykunst, B. 2. Kap. 11. Pott's observations relative to the disorder of the comer of the eye, commonly called the Fistula Lachrymalis, 8 vo. Loud. 1758. Sir W. Bli- zard , A New Method of treating the Fistula Lachrymalis, 4lo. Lond. 1780. Ware on the Epiphora and Fistula Lachrymalis; 8vo. Lond. 1792 — 95. Scarpa sulle principali Malattie degli Occhi, Capo 1. Walken's New and easy Method of applying a Tube for the Fistula Lachrymalis, Lond. 1781, and 2d Ed. 1792. Sprengel, Geschichte der Wichtigsten Chir. Operalionen, p. 105. Nicod, Memoire sur la Fistule Lacrymale in Revue M6d. Historique, fyc. livr. 1 et 2, 8 vo. Paris, 1820. Fournier, Diss. de lAppare.il des voies lachrymales ; Montpellier, 1803 J. L. Angely, Cornmentatio Medica de Oculo Organisque La- chrymalibus ratione Alt at is, Sexus. Gentis, et Variorum Animalium . S vo. Erlangce, ISOS. Reil, Diss. de Chir. Fistulas Lachrymalis Cu- ratione, Berol. 1812; Flajani , Collezione d' Os- servazioni, T. 3. Desault, (Euvres Chir. T. 2,p. 119, 8 vo. Paris, 1801. J. C. Rosenmul- ler, Partium Externarum Oculi Humani , im- primis Organorum lachrymalium, Descriplio Anatomica ; ico?iibus illuslrata, 4 to. Lips. 1810. C. H. T. Schreger, Versuch einer Vergleichenden Anatomic des Auges und der Tiirdnenorgane des Menschen und der vbrigen Tkitrklassen, 8vo. Leipz. 1810. Beer, Lehre von den Augenkrankheiten^ 2 B.Sco. Wien, 1813 — 1817. Wm. Mackenzie, An Essay on the Diseases of the Excreting Parts of the La- chrymal Organs, 8 vo. Lond. 1819 ; contains many valuable observations from the writings of Beer . B. Travers , A Synopsis of the Dis- eases of the Eye,p. 228 — 359, fyc. 8 vo. Lond. 1820. Ph. v. Waltaer ueber die steinigen Concrctionen der Thrcinenjlussigkeit, in Journ. far Chirurgie von C. Graefe, B. I, p. 163. iSl 8vo. Berlin, 1820. J. A. Schmidt iiber die Krankheiien des Thriineuorgans ; a work of the highest reputation. L AGOPHT H AL MIA, orLAGOPHTHAL MOS. (from \oyos, a hare ; and c< an eye.; The Hare's Eye. Oculus Leporinus. A disease, in which the eye cannot be com- pletely shut. The following complaints may arise from it ; a constant weeping of the organ, in consequence of the interrup- tion of the alternate closure and opening of the eyelids, which motions so materially contribute to the propulsion of the teurs into the nose ; blindness in a strong light, in consequence of the inability to moderate the rays, which enter the eye ; on the same account, the sight becomes gradually very much weakened , incapacity to sleep where there is any light; irritation, pain, andredne s of the eye, from this organ being exposed to the extraneous substances in the atmos- phere. An enlargement, or protrusion of the whole eye, o a staphyloma, may obviously produce lagophthalmos. But, affections of the upper eyelids are the common causes. Heister lias seen the complaint originate from a disease of the lower one. Now and then lagophthalmos depends on paralysis of the orbicularis muscle. A cicatrix, after a wound, ulcer, or burn, is the most frequent cause. When lagophthalmos arises from a paraly- tic affection of the orbicularis palpebrarum, the eyelids may be rubbed with a liniment containing the tinctura lyttas, or the linimen- tum camphorae. Electricity and cold bath- ing are also considered principal means of cure, ( Chandler ) together with the exhibition of bark, the use of the shower-bath, &c. When the affection arises from spasm of the levator palpebrai superioris, electricity, admail blister on the neighbouring temple, and rubbing the eyelid and eyebrow with the tinctura opii, are recommended, together with antispasmodic medicines. WTien lagophthalmos arises from the con- traction of a cicatrix, its relief is to be at- tempted precisely on the same principles a5 the ectropium. (See Ectropium .) How ever, when*the eyelid is shortened as well as everted, nothing will remove the defor- mity The inconveniences, depending on the eye being unable to shelter itself from the light, are to be obviated by wearing agreeri shade. Whoever is acquainted with German, and is desirous of more minute information on this subject, may find an excellent account of lagophthalmos in Richter's Anfavgsgr. der Wundarzn. B. 2. Von dem Hasenauge. See also Beer's Lehre von den Angenkr. B. 2, p. 239, 8fC. 87-0. Wien, 1817. LARYNGO 1'OMY. (from the la- rynx; a nd^Mva, to cut.) The operation of making an opening into the larynx. (See Bronchotomy .) LATERAL OPERATION. One mode of cutting for the stone. (See Lithotomy LENTICULAR, (from leniim!aire r doubly convex.) An instrument, contained in every trephining case, and employed for removing the irregularities of bone from the edge of the perforation, made in the cranium with the trephine. One side of its blade is con- vex, the other concave ; and one of its edges is sharp. On the end of the blade is fixed a little shallow cup, with its concavity towards the handle of the instrument. This part serves the purposes of receiving the little pieces of bone, when detached, keep- ing the end of the blade from hurting the dura mater, and, when applied under the margin of the opening, enables the operator to guide the edge of the instrument all round it, w ith steadiness and security. LEUCOMA. (from \euxos, white.) Leu- comaand albugo are often used synonymous- ly, to denote a white opacity of the cornea. Both of them, as Scarpa remarks, are essen- tially different from the nebula of the cornea ; for, they are not the consequence of chronic ophthalmy, with varicose veins, and an effusion of a milky serum into the texture of the delicate continuation of the conjunctiva over the cornea ; but, are the result of vio- lent acute ophthalmy. In this state, a dense coagulating lymph is extravasated from the arteries ; sometimes superficially, at other times deeply into the substance of the cornea. On other occasions, the disease consists of a firm callous cicatrix on this membrane, the effect of an ulcer, or wound, with loss of substance. The term albugo , Strictly belongs to the first form of the disease ; leucoma to the last, more particularly when the opacity occupies the whole, or the chief part, of the cornea. The recent albugo, remaining after the cure of severe acute ophthalmy, is of a clear milky colour; but, when of ancient date, it becomes pearl-coloured. Some cases, which have existed a considerable time, do not seem to have any connexion with the vascu- larity of the cornea ; for they continue insu- lated in the middle of the transparent por- tion of this membrane, withoul occasioning the least uneasiness to the patient, the least disturbance of the rest of the eye, or any attempt of the absorbents to remove them. The recent albugo, provided* the organi- zation of the cornea be not destroyed, may generally be dispersed by the means em- ployed for the relief of the first and second stages of acute ophthalmy; viz. general and topical blood-letting with internal antiphlo- gistic medicines, and topical emollients for the first; slightly irritating and corroborant applications for the second- As soon as the inflammation has subsided, the latter ^should be employed ; for, by making the absorbents remove the coagulating lymph, deposited in the cornea, they restore the transparency of this membrane. But, though this may often be accomplish- ed in the recent state of albugo, it is more difficult when the long duration of the dis- ease has paralyzed the absorbents of the af- fected part ; or when the deposition of a dense tenacious substance into the cornea has subverted its organization- (Scarpa.) The recent condition of the disease, with out disorganization of the structure of the cornea; its occurrence in young subjects, whose absorbents are readily excited by ex- ternal stimulants; are circumstances favour- able to the cure. In children, the albugo, arising from severe ophthalmy after the small pox, and insulated in the centre of the cornea, very often disappears of itself in the course of a few months. Heister, Langguth, and Richter, make the same observation. The event can only be imputed to the vigor- ous action of the lymphatics in children, and to the organization of the cornea not being destroyed. For promoting the absorp- tion, Scarpa recommends the following colly- rium : 3 ,. Ammon, muriata*. Qij.Cupri acetati gr. iv. Aquae Calcis^viij. Misce, The fluid is to be filtered, after standing twenty-four hours. He praises also this ointment : Tutiae praepar. 3j- Aloes, s. p. gr. ij. Hydrargyri submur. gr. ij. Adipis suillae. 55 s. Misce And the unguentum ophthalmicuin of Janit?. He mentions the gall of the ox, sheep, pike, and barbel, applied to the cornea, two or three times a day, with a small hair pencil, if top much irritation should not be produced. In some subjects, when the eyes are very irri- table, and cannot bear the latter applications, Scarpa has found the oil of walnuts an use ful application. But it is generally neces- sary to persevere, at least three or four months, before the case can be reckoned in- curable. All the expedients, proposed for the inve terate albugo or leucoma from a cicatrix, consisting of scraping or perforating the layers of the cornea, and exciting ulceration there, are unavailing. For, though the en- largement of the cornea should be lessened by such means, its diaphanous state could not be restored ; or should the patient per- ceive a ray or two of light immediately after the operation, the benefit would only be transient; for, as soon as the wound had healed, the opacity would recur. The for- mation of an artificial ulcer might prove use- ful, if leucoma depended on a mere extrava- sation of lymph ; but, the fact is, the disease arises from the deposition of an opaque sub- stance, and the disorganization of the tex- ture of the cornea, conjointly : in this lies the difference between albugo and leucoma. See Scarpa suite Malatlie degli Occhi ; 8 vo. Venezia, 1802. Richter, Anfangsgrunde dec Wundarzn. B. 3. Essays on the Morbid Ana- tomy of the Eye, by J. IV ar dr op ; Edinb. 1808 : chap. 11. LIGATURE. In the article Hemorrhage , it has been explained, that the immediate effect of a tight ligature on an artery, is to cut through its middle and internal coats, a circumstance that tends very much to pro- mote the adhesion of the opposite sides ot the vessel to each other. Hence, 1 think with Dr. Jones, in opposition to Scarpa,' that the form and mode of applying a ligature to an artery should be such, as are most certain of dividing the above coats ot tin*, vessel, in a regular manner. A broad flat ligature does not seem likely to answer H 1 > ■ LIGATURE. purpose well ; because it is scarcely possible to t:e it smoothly round the artery, which is apt to be thrown into folds, or to be puck ered by it, and, consequently, to have an irregular bruised wound made in its middle and internal coats. (Jones.) A ligature of an irregular form is likely to cut through these coats more completely at some parts, than others; and if.it does not perfectly divide them, though adhesion may yet take place, it is a slower and less certain event, and secondary hemorrhage more likely to follow. The fear of tying a ligature too tight may often lead to the same disadvan- tages. ihese, and many other important circumstances, are noticed in the article Hemorrhage. Ligatures are commonly made of inkle, and rubbed with white wax. They should be round, and very firm, so as to allow being tied with some force, without risk of break- ing. (See Jones on Hemorrhage , p. 172.) The principles, which should guide the surgeon in the use of the ligature, were not known until the late Dr. Jones published his valuable treatise on hemorrhage. As an able surgeon has observed, “ he has banished (at least in this country) the use of thick and Ibroad threads, of tapes, of reserve ligatures, of cylinders of cork and wood, linen coin presses, and all tLi€5 contrivances, 'which, em- ployed as a security against bleeding, only served to multiply the chances of its occur- rence.” ( Lawrence , in Med. C/iir. Trans. Vol. 6, p. 162.) In the article Amputation , l have noticed the method of cutting off both ends of the ligature close to the knot, on the face of the stump, with the view of lessening the quan- tity of extraneous matter in the wound, and promoting a complete union of the divided parts, without suppuration This plan has been tried by Mr. Lawrence : u The method I have adopted (says this gentleman) consists in tying the vessels with fine silk ligatures, and cutting off the ends as close to the knot as is consistent with its security, Thus the foreign matter is reduced to the insignificant quantity, which forms the noose actually surrounding the vessel, and the knot, by which that noose is fastened. Of the silk, which i commonly employ, a portion sufficient to tie a large artery, when the ends are cut off, weighs between one- fiftieth and one-sixtieth of a grain : a similar portion of the thickest kind I have tried, weighs one-twentieth of a grain, and of the slenderest one-eightieth.” Mr. Lawrence states, that the kind of silk twist which is commonly known in the shops by the name of dentist’s silk, and which is used in making fishing lines, is the strongest material, in proportion to its size, and therefore the best calculated for our purpose, which requires considerable force in drawing the thread tight enough lo di- vide the fibrous and internal coats of the arteries. This twist is rendered very hard and stiff by means of gum, which may be removed by boiling it in soap and water ; but the twist then loses a part of its strength. ina The stoutest twist which Mr. Lawrence has used, is a very small thread comp red with ligatures made of inkle. The quantity of such a thread, necessary for the noose and knot on the iliac artery, weighs one-twenti- eth of a grain ; or, if the gum has been removed, about one-twenty-sixth. But the finest twist, kept in the silk shops, is strong enough in iTS hard slate for any surgical purpose ; and the noose and knot, accord- ing to Mr. Lawrence’s statement, would not weigh one-fortieth of a grain. It anther appears, from the report of this gentleman on the subject, that there is no danger ot these ligatures cutting completely through the vessel, as some surgeons have apprehended; and that, although he has not yet ascertained what becofnes of the piece of ligature after the wound is united, he has never seen abscess nor any other bad symptom occasioned by them. At the time when Mr. Lawrence wrote, he had employ- ed this method of securing the arteries in ten or eleven amputations, in six operations Oil the breast, and in the removal of two testicles. The cases all did well, excepting a man w ho lost his thigh, and who died of an affection of tne Sungs. (See Lawrence on a JYew Method of Tying the Arteries in Aneu - rism, 4’C. in Medico- Chit. Trans. Vol. 6, p. 156, Hfc.) The foregoing method was tried by myself in several amputations, which 1 performed in 1815 at Brussels, and in a larger number of cases by my friend, Mr. Collier. Our ligatures, however, though small, were not so small as those judiciously recommended by Mr. Lawrence ; and, on this account, no accurate inferences can be drawn from our examples, which, however, as far as I could learn, were not unfavourable to the practice. This subject was mentioned by Mr. Gu- thrie, as follows : — Some military surgeons, both French and English, have lately adopt- ed the practice of cutting off’ both ends of the ligatures close to the knot on the artery, uniting the parts, if possible, over them, and allowing the knots to find their way out as they can. The edges of the wound, in some instances, have united thoroughly in a few days, and when the knots have come off the ends of the arteries, they have caused small abscesses to be formed, which point at the nearest external surface, and are discharged with little uneasiness. 1 know that many cases, treated in tills manner, in the cam- paign of 1813, ended successfully, and heal- ed in as short a time as the most favourable ones by the usual method ; and at Montpel- lier, in June, 1814, Motis. Delpech, Professor of Surgery in that university, showed ine at least twenty cases in which he had, and was still practising this method with success. 1 have seen, however, in two or three instan- ces, some ill-looking abscesses formed by them, and I suspect some disagreeable con- sequences .will ensue, if this practice be continued. “ I consider this improvement as very va- luable in all cases, that will not unite by the first intention. The ligatures, if there he many, form into ropes, ano the cause of much irritation, and are frequently pulled away with the dressings ; by cutting them off. these evils are avoided, and the knots will come away with the discharge. 7 (See Guthrie on Gunshot IVounds of the Extremities, p. 93, 94.) With respect to the abscesses, which this gentleman saw produced by the method, it is properly observed by Mr. Lawrence, that as this statement is not accompanied by any description of the materials, or size of the ligature, nor by any details of the unfavour- able cases, we cannot judge, whether the events alluded to are to be attributed to f.he method itself, or to the way in which it was executed. (See fifed. Chir. Trans. Vol. 6, p. 171.) M. Roux has tried the plan in three ope- rations on the breast ; the £ases did well ; and no ill consequences arose from the presence of the bits of thread under the cicatrix. (See Relation d'un Voyage faith Londres en 1814, ou Parallele dtla Chiruraie Angloise avecla Chirurgie Franchise; Paris, 1815. p. 134 — 136.) For other remarks, connected with the foregoing topics, see Amputation, Aneu- rism,, and Hemorrhage. LIMMENTUM ACIpI SULPHURICI. — Olei Olivae 3 i -s. Acid. Sulph. ~;s. M. Recommended by Mr. Bi odie, for the remo- val of the effects left by inflammation of the synovial membrane. (See Joints.) LIMMENTUM AMMONIA FORTIUS. - — 1^. Liq. ammou. Zj. Qlei olivae §iij. Misce. Proper! ies stimulai in g. LIMMENTU VI CALCIS — ft. Aquae cal- cis, Olei olivae, sing. |viij. Spirit, vinosi recti- fieati Misce. A common application to burns and scalds. LINI vIENTUM CAMPHORS COMPO- S1TUM. ft. Camph. ^ij. Aq. atnmon. ^vj. Spirit, lavend. ^xvj Sixteen ounces are to be distilled of the two last ingredient-, from a glass retort, and the camphor then dissolved in the distilled fluid. For bruises, sprains, rigidities of the joints, incipient chilblains, &e. LIMMENTUM CAMPHOR/E A FH E- I1EUM. — ft Camphurae drach. j. Atheris unc. ss. Olei. viperarma drach. ij. Misce The camphor is to be dissolved in (lie aedier, and the oil afterw rd incorporated with it. The lale Mr. Ware sometimes used this ap- plication, in certain obscure affections of the eye, in which it was not easy to determine, whether the imperfection of the sight pro- ceeded from an incipient cataract, or a defect of sensibility in the optic nerve. The mode of applying it is to moisten the finger with it, and to rub it for two or three minutes toge- ther, morning and evening, on the outside and edges of the eyelids. (Pharm. Chirurgica.) LIMMENTUM HYDKARGYRI CO.Vi- POSITUM — ft. Ung. hydrargyri fortioris, Adipis suillae, sing. §i. Camph, 3 j Spirit, vinos, rectif. 3>j- Liq. ammou. ?j. The camphor being dissolved in the spirifof wine, add the liq. amtnon. and the ointment pre- viously blended with the hog’s lard. (Pharm. Sancti. Barlhol.) An excellent formula for all surgical cases, in which the object is to quicken the action of (lie absorbents, and gently stimulate the surfaces of parts. It is a capital application for diminishing a chro- nic indurated state of particular muscles, every now and then met with in practice • and it is particularly well calculated for les- sening the stiffness and chronic thickening often noticed in the joints. LIMMENTUM POTASSA SULPHU- RETI. — Saponis Albi... ^iv. Olei Amyg- dalae |viij. Potassae Sulphureti 3 v j- Olei Thy mi gr. xv. vel 3j. This liniment, used twice a day, will cure the itch in five days, or, at latest, in eight. It has very little un- pleasant smell, and would be preferable to sulphur ointment, if equally efficacious. (See London Medical Repository, Vol. 3, p. 242 and Cross's Sketches of the Medical Schools of Pa- ris ,p. 176.) L1NMENTUM SAPONIS COMPOSi- TU.*j. — ft. Sapon. ?iij. Camph. ^j. Spi- rit. rorismar. iftj. Dissolve the soap in the spirit, and then add the camphor. Uses the same as those of the iinimenturn camph. LIMMENTUM SAPONIS CUM OPIO, ft. Lin. sapon. comp. ^vj. Tinct. opii. ^ij. Misce. For dispersing indurations and swell- ings attended with pain, but no acute inflam- mation*. LIMMENTUM TEREBINTHINA.— ft. Ung. resinse fiavae ^iv. 01 terebinthina?, q. s. Misce. The well-kno&n application for burns, recommended by Kentish. (See Barns.) LIMMENTUM TEREBINTHINA SUL- PHURICUM. — ft. Olei oiivee 3X. 01. te rebinth. 3iv. Acidi Sulph: 3 * *« j - Misce. Said to be efficacious in chronic affections of the joints, and in the removal of the old effects of sprains and bruises. (Pharm. Chirurgica .) LIP, CANCER OF. The lips are subject to ulcers, which put on a very malignant as- pect, although some of them are not in re- ality malignant ; and many occurring just on the inside of these parts, will be found to depend on the bad state of the constitution, and the irritation and disturbance which the sores are continually suffering from the inces- sant motion of the parts, and their rubbing against a projecting, or rough tooth. Arsenic is frequently useful in subduing the obstinacy and malignity of certain ulcers and diseases of the lip, reputed to lie cuncerous. (Stark, Dc Cancro Labii Inferioris.) Ot this essay. P otessor Langenbeck speaks in high terms. Tue following formula is recom- mended. ‘‘ ft. Arsenici Albi drachm dimid. Aq. comm stfflaticiai unc. sex. M. Digeranlur vase vitreoclauso in balueo arenas justi ca- loris ope per boras sex, turn adde Potassai Carbon) is pura? drachm, dimid. antea soluf. in aq. Cinnamon, sjmpl. unc. duab. M. Dige- rantur denuo per aliquot horas in loco tem perato. Mac solutione bis terve quotidie ad guttas 8 — 10 — 15, utimur.” When cancer takes place, it is usually in the lower, and very seldom in the upper lip. The disease sometimes puts on the appear- ance of an ulcerated, wart-like excrescence, occasionally acquiring a considerable size. Sometimes it is seen in the form of a very destructive ulcer, which consumes the stir- LIQUOR. 185 rounding substance of the lip ; and, in other examples, the disease resembles a hard lump, which, at length, ulcerates. The disease, in its infancy, is often no more than a pimple, which gradually becomes malignant. When- ever there is reason to believe, that the dis- ease is of an unyielding cancerous nature, and it does not soon give way to arsenic, hemlock, and mercurials, the sooner it is ex- tirpated the better. For this purpose, some surgeons admit the propriety of using caus- tic, when the whole disease can he com- pletely destroyed by one application. But as the action of caustic is not capable of being regulated with so much precision as the ex- tent of a wound can be, and as caustic will not allow the parts to be united again, the knife is the only justifiable means, especially as it occasions also less pain. Two incisions are to be made, meeting at an angle below (supposing it to be the lower lip,) and inclu- ding the whole of the disease. The sides of the wound are then to be united by the twisted suture. (See Hare-Up.) When the affection is extensive, however, the surgeon is frequently necessitated to remove the whole of the lip, or too much of it to admit of the above plan being followed. This circumstance is particularly unpleasant, as the patient's spittle can only be prevented from continually running over his chin by some artificial contrivance. The deformity also is very great, and pronunciation and swallowing can only be imperfectly per- formed. LIPPITUDO. (from lippus, blear-eyed.) Blearedness. The ciliary glands, and lining of the eyelids, only ^secrete, in the sound state, a mere sufficiency of a sebaceous fluid to lubricate the parts in their continual mo- tions. But, it sometimes happens, from dis- ease, that this sebaceous matter is secreted in too great a quantity, and glues the eye- lids together during sleep, so that, on waking, they cannot be easily separated. Hence, the margin of the eyelids becomes red all round, and the sight itself even weakened. The best remedies are the unguentum liy- drargyri nitrati, smeared, at night, on (lie edges and inside of the eyelid with a hair pencil, after being melted in a spoon ; the unguentum tutiae, applied in the same way ; and a collyrium, composed of 3j. of the sulphate of zinc in v^iij. of rosewater. "When alterative medicines are requisite, a grain of calomel may be exhibited daily, or the compound calomel pill, containing one grain of calomel, one of sulphur anti- monii preecipitatum, and two of guaiacum, put together with soap. Persons who have lippitudo and cataracts together, bear couching much better than one would expect from the appearance of the eyes in that disease ; and Mr. Hey never rejects a patient on this account, provided such state is habitual. ( Practical Observa- tions, p. 51.) Scarpa, however, recommends the lippitudo to be removed before the operation is undertaken. LIQUOR AMMON. ACET. (L. P.)— This is given in the dose of half an ounce in Vol. II. 24 many surgical cases, in which the object is to keep up a gentle perspiration. LIQUOR ARSEN1CALIS.— ft. Arsenic! Oxydi pneparati in pulverem subtilissimuni triti, Potassa? Subcarbonatis ex tartaro, sin- gulorum gr. 64. Aq. distill, jfej coque si.mul in vase vitreo, donee arsenicum omne lique- tur. Liquori frigefacto adjice Spiritfts Lavan- dulae com. 3iv. Denique adjice insuper Aq. distil, quantum satis sit, ut inensurarn octarii accurate impleat. For internal use the dose is iv. drops gradually increased to xx. twice a day. It is frequently given in cases of anomalous ulcers, and cancerous affections of the lip. It is also used as an external application in similar cases, and especially in hospital gangrene. (See Arsenic , and Hospital Gangrene,) LIQUOR CALCIS (L. P.)— Sometimes used as an astringent injection, or lotion, in cases of gonorrhoea, gleet,, psora, porrigo, abscesses, &c. LIQUOR CUPRI SULPHATIS CAM- PHORATA. — 1^, Cupri sulphatis. Boli Gal- lici sing. une. ss. Camphorm drach.j. Aquas ferventis lib. iv. Boiling water is to be added to the other ingredients, and the liquor filtered when cold. It is chiefly employed in a diluted state, as a collyrium ; hopit may also prove of service as an application to foul ulcers. When used for the cure of the purulent ophthalmy, the lotion is to be injected under the eyelids, by means of a blunt syringe, and, if necessary, the application may be repeated once or twice every hour. (See Ophthalmy.) LIQUOR POTASSES SUBCARBONATIS (L. P.) — This remedy is principally deserving of notice on account of its having been given with a view of dissolving calculi in the bladder, so as to remove the necessity of performing the dangerous and painful operation of lithotomy. The principle, on which the liquor potassm subcarbonatis acts, is by the potassa attracting and combining with the uric acid of the calculus. The medicine may be exhibited in doses of 20 or 40 drops, or of a dram, in a basin of gruel. Experience does not seem to justify the indulgence of much hope, with regard to the complete efficacy of the medicine in dissolving urinary calculi, and on some kinds it is not calculated to act at all, even ou chymieal principles ; but, it would appear, from the reports of writers, that it has often materially palliated the pain which attends the presence of a stone in the bladder. Some practitioners place more confidence in the liquor potassae. LIQUOR KALI ARSENIC ATI, ■ — ]J. Kali Arsenicati grana duo. Aquae Menthae Sativa^ uncias quatuor. Spiritus Vinosi tenuiori^l unciam. Misce et cola. Two drams of this may be given thrice a day in cases of cancer. My friend, Mr. Barnes, oi Exeter, when for- merly a student at St. Bartholomew's, show- ed me a case of lupus, or noli me tangere, which was greatly benefited by this remedy externally applied. Mr. Barnes was using the lotion with double the proportion of LITHOTOMY arsenic. There are many ulcerations round the roots of the nails of the (ingers and toes, to which Plunket’s caustic is sometimes applied ; but, the liquor kali arsenicati would, in all probability, be <|uite as effica- cious, and, certainly, it is a neater applica- tion. LIQUOR TOTASS^E (L. P.) This has been given with a view of dissolving urinary calculi, in considerable doses> for a length of time. The trials, however, have not pro- ved so successful as could have been wish- ed, nor is the exhibition of so active a re- medy unattended with disadvantageous consequences to the system; for which reason, soda water and other alkaline wa- ters, supersaturated with fixed air, have of late been much substituted. The proper dose of the liquor potassse at first, is from ten to twenty drops twice a day, in some linseed tea. At St. Thomas’s Hospital, the following is the way in which the liquor potasssk is prescribed : — Liq. Potass;e §i. Aquae Distillatae %\j. Misce. Dosis Drachma una bis die ex unciis quatuor infusi liui. LIQUOR PLUMB! ACETATJS (L. P.) — Is extensively used, largely diluted with water, as an application to inflamed parts. (See Inflammation.) One dram to a quart of water is quite strong enough for common purposes. Mr. Justamond and Dr. Cheston used to apply it, mixed with an equal pro- portion of a spirit resembling the tinctura lerri muriati, to the edges of cancerous sores. k LITHONTRIPTICS. (from wfloc, a stone ; and d-gv7rra>, to break.) Medicines for dis- solving stone in the bladder. (See Urinary Calculi.) ^'LITHOTOMY, (from xtSog, a stone; and ; Haller’s Inst. Med. of Bo- erhaave, and Elem. Physiol. T. 5 ; Mor- gagni, Adversar. Anat. 3, p. 82, 97 ; Cam- per’s plates ; Sabatier’s Anatomy ; John Bell's Principles of Surgery ; Deschamp’s Trailts Historique, fee. de [’Operation de la Taille, T. 1, p. 7, fee.; and Langenbeck’s description of the parts, and the matchless plate which he has given of them in his valuable work on lithotomy, cited at the end of this article. /V few subjects which are closely connect- ed with the present, will be found in other parts of this dictionary. For instance, the nature of stones in the bladder will be consi- dered under the head of Urinary Calculi , where also will be seen some observations on lithontriptics. The manner of searching for the stone, or, as it is now more common ly expressed, of sounding, will be explained in the article Sounding. Here I shall principally confine myself to the symptoms of the disease, and the chief’ methods of executing the much diversified operation of lithotomy. SYMPTOMS OF THE STOKE. The symptoms of a stone in the bladder are, a sort of itching along the penis, parti- cularly at the extremity of the glans ; and hence the patient often acquires a habit of pulling the prepuce, vvhich becomes very much elongated ; frequent propensities to make water, and go to stool ; great pain in voiding the urine, and difficulty of retaining it, and often of keeping the feces from being discharged at the same time ; the stream of urine is liable to stop suddenly, while flow- ing in a full current, although the bladder is not empty, so that the fluid is expelled bv fits, as it w^ere ; the pain is greatest towards the end of, and just after, the evacuation ; there is a dull pain about the neck of the bladder, together with a sense of weight, or pressure, at the lower part of the pelvis ; and a large quantity of mucus is mixed with the urine ; and, sometimes, the latter is tinged with blood, especially after exercise. ( Sharpy Earle , Sabatier.) Frequently (says Deschamps) a patient will have a stone in his bladder a long while without the occurrence being indicated by any symptom or accident. Most commonly, however, the presence of the stone is an- nounced by pain in the kidneys, more espe- cially in adults and old persons, children scarcely ever suffering in this way, because in them the stone is hardly at all detained in the kidneys and ureters, but descends im- mediately into the bladder, the preceding LITHOTOMY - 18V tubes being in them more dilatable, and the rudiment, or nucleus of the stone smaller. It seldom happens, that calculous patients void blood with their urine, before the symp- toms and accidents, usually caused by the stone, have taken place. It is not till after the foreign body has descended into the bladder, acquired some size, and presented itself at the orifice of that viscus, that pain is occasioned, particularly when the surface of the stone is unequal. The patient then ex- periences frequent inclination to make wa- ter, attended with pain. The jolting of a carriage, riding on horseback, and much walking, render the pain more acute. The urine appears bloody, and its course is fre- quently interrupted, and sabulous matterand particles of stone are sometimes discharged with it. The want to make water becomes more frequent and more insupportable. The bladder is irritated, and infiames ; its parietes become thickened and indurated ; and its diameter is lessened. A viscid, more or less, tenacious matter is observed, in greater or lesser quantity, in the urine, and is pre- cipitated to the bottom of the vessel. The urine becomes black and putrid, and exhales an intolerable alkalescent smell, which is perceived at the very moment of the evacua- tion, and is much stronger a little while af- terward. The patient can no longer use any exercise, without all his complaints be- ing redoubled. Whenever he walks in the least, the urine becomes bloody ; the pain about the hypochondria, which was dull in the beginning, grows more and more acute ; the ureters and kidneys participate in the ir- ritation with the bladder; they inflame and suppurate, and very soon the urine brings away with it purulent matter. The fever increases, and changes into one of a slow type ; the patient loses his sleep and appe- tite ; becomes emaciated and exhausted ; and death at length puts a period to his mise- ry. (See Traits Historique et Dogmatique de /.'Operation de la Taille par J. F. L. Des- ehamps, T. I, p. 163, Paris , 1796.) It is acknowledged by the most experien- ced surgeons, that the symptoms of a stone in the bladder are exceedingly equivocal, and may be produced by several other dis- orders. “ Pain in making water, and not being able to discharge the urine without the feces, are common consequences of ir- ritation of parts about the neck of the blad- der, from a diseased prostate gland, and other causes. The urine stopping in a full stream is frequently caused by a stone alter- ing its situation, so as to obstruct the pas- sage; but the same thing may happen from a tumour, or fungus in the bladder. I have seen an instance of this, where a tumour, hanging by a small pedicle, would sometimes cause obstruction, and by altering the pos- ture, would retire, and give a free passage. The dull pain at the neck of the bladder, and the sensation of pressure on the rectum, are frequently owing to the weight of the stone, &c. ; but these may proceed from a diseased enlargement of the prostate glan^. Children generally, and grown persons frequently, are subject to a prolapsus ani, from the irritation of a stone in the bladder;, but it will like- wise be produced by any irritation in those parts.” (Earle.) The rest of the symptoms are equally fallacious ; a scirrhous enlarge- ment of the os tincae, and disease of the kid- neys may occasion a copious quantity of mucus in the urine, with pain, irritation, &c. “ The least fallible sign (says Sir James Earle) which I have remarked, is the patient making the first portion of urine with ease, and complaining of great pain coming on when the last drops are expelled. This may readily be accounted for, from the bladder being at first defended from contact with the stone by the urine, and, at last, being pressed naked against it. But, to put the matter out of all doubt, and actually to prove the exist ence of a stone in the bladder, we must have recourse to the operation of sounding.' A stone in the ureter, or kidneys, or an in- flammation in the bladder from any other cause, will sometimes produce the same ef fects ; but if the patient cannot urine, ex- cept in a certain posture, it is almost a sure sign that the orifice of the bladder is ob- structed by a stone. If he finds ease by pressingagainstthe perinaeum with his fingers, or sitting with that part upon a hard body, there is little doubt the ease is procured by taking off the weight of the stone ; or, lastly, if, with the other symptoms, he thinks he can feel it roll in his bladder, it is hardly pos- sible to be mistaken ; however, the only sure judgment is to be formed from searching. (Sharp on the Operations.) An enlarged prostate gland is attended with symptoms resembling those of a stone in the bladder ; but with this difference, that the motion of a coach, or horse, does notin- crease the grievances, when the prostate is affected, while it does so in an intolerable degree in cases of stone. It also generally happens, that the fits of the stone come on at intervals ; whereas, the pain from a disea- sed prostate is neither so unequal, nor so acute. ( Sharp in Critical Inquiry , p. 165, Edit. 4.) Though, from a consideration of all the circumstances above related, the surgeon may form a probable opinion of there being a stone in the bladder, yet he must never presume to deliver a positive one, nor ever be so rash' as to undertake lithotomy, with- out having greater reason for being certain thatthere is a stone to be extracted. Indeed, all prudent surgeons, for centuries past, have- laid it down as an invariable maxim, never to deliver a decisive judgment, nor under- take lithotomy, without having previously- introduced a metallic instrument called a sound, into the bladder, and plainly felt the stone. Within the last five years, at least seven cases have corne to my knowledge, and at two of them I was present, where the pa- tients were subjected to all the torture and perils of this operation, without there being any calculi in their bladders. The maxim, therefore, cannot be too strictly enforced, that the operation ought never to be at- 188 UthotomY. tempted, unless the stone can be distinctly felt with the sound or staff. In one of the examples, of which I was a spectator, not only the symptoms, but the feel, which the sound itself communicated when in the bladder, made the surgeons imagine, that there was a calculus, or some extraneous body in this organ. Mostof the above cases, I understand, recovered, which may be con- sidered fortunate ; because when the stone cannot be found, the disappointed operator is apt to persist in roughly introducing his fingers, and a variety of instruments, so long, in the hope of catching what cannot be got hold of, that inflammation of the bladder and peritoneum is more likely to follow, than when a stone is actually present, soon taken out, and the patient kept only a short time upon the operating table. In a valuable practical work is recorded an instance, in which what is called a horny cartilaginous state of the bladder, made the sound communicate a sensation, like that arisingfrotn the instrument actually touching a stone, and the surgeon attempted lithoto- my. This patient unfortunately died in twenty-four hours. (See Desault's Parisian Chir. Journal , Vol. 2 ,p. 125.) However, were the symptoms most une- quivocal, there is one circumstance which w ould always render it satisfactory to touch the stone with an instrument, just before venturing to operate ; I mean the possibility of there actually being a stone in the bladder to-day, and not to-morrow. It is said, that stones are occasionally forced, by the vio- lent contractions of the bladder, during fits of the complaint, between the fasciculi of the muscular coat of this viscus, together xvith a portion of the membranous lining of the part, so as to become what is termed encysted. The opening into the cyst is frequently very narrow, so that the stone is much bigger than the orifice of the cyst, in consequence of which it is impossible to lay bold of the extraneous body with the forceps, and the operation would necessa- rily become fruitless. ( Sharp's Critical In- quiry, p. 228, Edit. 4.) In the article Urinary Calculi, I have no- ticed the probability of this having occur- red in some of the instances in which Mrs. Stevens’s medicine was supposed to have actually dissolved the stone in the bladder; lor an encysted stone is not likely to be hit with the sound, nor to cause any inconve- nience, compared with what u calculus, rolling about in the bladder, usually oc- casions. It is remarked by Deschamps, that when the stone is lodged in an excavated corner of the bladder, in a particular cyst, or de- pression ; when it projects hut very little ; when it cannot shift its situation in the blad- der, so as to fall against the orifice of this viscus ; and when it is also smooth, polished, and light; the patient may then have it a long while without experiencing any afflict- ing symptoms. He may even live to an advanced age, if not without some degree of -uffering, at all events, with such pain as is very supportable. Daily experience prove*, that persons may live a considerable time, with one, two, or even three stones in the bladder, and, during the whole of their lives, have not the least suspicion of the existence of these foreign bodies. According to Deschamps, this must have been the case of M. Portaiieu, a tailor. This individual, eighty years old, was frequently attacked with a retention of urine from pa- ralysis, and Deschamps introduced a sound several times, and distinctly felt a stone in the bladder.” The patient, however, never had any symptom of the disorder, nor even at the end of two years from the time when Deschamps was first consulted. Very large and exceedingly rough stones have also been found in the dead bodies of persons who had never complained of the symp- toms of the disease. Thus, at the anatomi- cal Theatre of La Charit6, Richerand found an enormous mulberry stone in the bladder of a person who died altogether of another disease, and never had any symptoms that led to the suspicion of the stone. ( JVoso - graphic Chir. T. 3, p. 530, Edit. 4.) But cases of this kind must be rare, because it is rvell known that the pain, which a stone produces, is less in a ratio to its size than to its shape and situation. A small stone, owing to its situation, may be more painful than an enormous calculus which fills the bladder, as is proved by the following case, by Deschamps. Pechet, a watchmaker, until the age of forty-five, had never had any infirmity, ex- cept that of not being able to retain his wa- ter a long while. One day, while he W’as carrying a very heavy clock, he made some exertions which probably, by changing the situation of the calculus, caused at the in- stant an acute pain in the hypogastric re- gion. Symptoms of the stone soon came on ; the pain became intolerable, and the patient went into the tlopital de la Charite. He was sounded ; the stone w r as felt, and judged to be of considerable size. The in- cision in the neck of the bladder not suffi- cing for its extraction, the patient was put to bed again. The next morning he was operated upon above the pubes by Frere Come, who extracted an oval calculus that weighed twenty -four ounces. The patient died four and twenty hours after this second operation. This case proves, then, that very large stones may lie in the bladder without occasioning any serious complaints, since the preceding patient apparently had had such a calculus a long time without suffering inconvenience from it, and it seems likely that he might have continued well still longer, had it not been for the acci- dental effort which first excited the symp- toms. ( Deschamps , in Traitc Hislorique , dc la Traille , Tom. 1, p. 166, 167.) A priest, in whom Morand had ascertain ed the presence of a stone by sounding, could not be persuaded that his case was of this nature. However, he bequeathed his body at hi^decease to the surgeons, and the tycsnnluatiol of the bladderfully justified Me- LITHOTOMY. 189 rand's prognosis. Tne celebrated D'Alem- bert also died with a stone in his bladder, having always refused to be sounded. ( Ri - chcrand, Op. cit. T. 3, p. 538.) A question may here suggest itself : ought lithotomy to be practised where calculi are under a certain size ? Certainly not, be- cause they frequently admit of being dis- charged with the urine, without any opera- tion at all, even from the male subject, and how much more likely this is to happen in females, must be plain to every body who recollects the direct course, the shortness, ample size, and dilatability of the meatus urinarius. On this subject, various facts will be adverted to in considering the ope- ration of lithotomy in women. Sometimes, also, when a calculus is too large to pass completely through the male urethra, it lodges in this passage, where it may be more safely cut upon and removed, than from the bladder; and sometimes it is actu- ally discharged by an ulcerative process. Thus, Dr. R. A. Langenbeck has published an example in which a stone made its way out by ulceration, and was discharged im- mediately behind the testes. (See J. C. Langenbeck, Bibl. ftir die Chir. Gott. 1809.) And G. Coopmans has recorded an almost incredible case, in which a calculus, weigh- ing five ounces, one drachm and a half, when being dried-, was discharged on the left side of the urethra of an elderly man, a little below the glans penis. In fact, with- out some further explanation, this case would be pronounced impossible , but it should be recollected, that after a small cal- culus has made its way out of the urethra by ulceration, if the urine have still access to it, it will continue to increase in size in its new situation ; and this is what happen- ed in the present example ; for the extrane- ous body, when first felt externally, was not larger than a pea. The calculus is now preserved in Camper’s museum. ( G . Coop- r nans , Keurologia , Svo. Franequerx, 1795.) I am not meaning, however, to recommend surgeons to let the patient encounter all the sufferings which must inevitably attend lea- ving the business to be completed by ulcera- tion, because, as soon as the nature of the , case is known, an incision should be made into the swelling, and the foreign body taken out. In many cases, also, small calculi may be voided by dilating the male urethra with elastic gum catheters of very large diameter, and then desiring the patient to expel his urine with considerable force, a plan which Baron Larrey has found repeatedly answer. Of late, Mr. Weiss, surgical instrument ma- ker, in the Strand, has invented a kind of sound, the end of which, when in the blad- der, admits of being opened, like a pair of forceps, and closed again, so as to grasp calculi under a certain size, and draw them out through the urethra. The instrument has been tried with great success by Mr. A. Cooper, who removed with it from one pa- tient at different times 84 calculi. And, even when the stone cannot be drawn com- pletely out of the urethra, but only into this passage, it is a great 'advantage, because, then it may easily be cut down to, and ex- tracted, without any w ound or injury of the bladder. (See A. Cooper in Med. Chir . Trans. Vol. 11.) I shall next describe the various methods of cutting for the stone, beginning with the most ancient, called the apparatus minor , and ending with the modern proposal of employing a knife in preference to a gorget. OF THE APPARATUS MINOR, CUTTING ON THE GRIPE, OR CELSUS’S METHOD. The most ancient kind of lithotomy was that practised upwards of two thousand years ago by Ammonius, at Alexandria, in the time of Heropbilus and Erasistratus, and by Meges, at Home, during the reign of Au- gustus; and. being described by Celsus, is named Litholhomia Celsiana. From cutting directly on the stone, fixed by the pressure; of the fingers in the anus, it has been called cutting on the gripe, a knife and a hook be- ing the only instruments used. The appel- lation of the lesser apparatus was given to it by Marianus, to distinguish it from a me- thod which he described, called the appara- tus major, {com the many instruments em- ployed. The operation was done in the following way. The rectum w T as emptied by a clys- ter a few hours previously ; and, immedi- ately before cutting, the patient was desired to walk about his chamber, to bring the stone down to the neck of the bladder; he was then placed in the lap of an assistant, or secured in the manner now practised in the lateral operation. The surgeon then in- troduced the fore and middle fingers of his left hand, well oiled, into the anus ; while he pressed with the palm of his right hand on the lower part of the abdomen above the pubes, in order to promote the descent of the stone. With the fingers the calculus was next griped, pushed forward toward the neck of the bladder, and made to protrude, and form a tumour on the left side of the perinaeum. The operator then took a scat- pel, and made a lunated incision through the skin and cellular substance, directly on the«tone, near the anus, down to the neck of the bladder, with the horns towards the hip. Then, in the deeper and narrower part of the wound, a second transverse inci- sion was made on the stone into the neck of the bladder itself, till the flowing out of the urine showed that the incision exceeded in some degree the size of the stone. The calculus being strongly pressed upon with the fingers, next started out of itself, or was extracted with a hook for the purpose. ( Celsvs , lib. 7, cap. 26. J. Bells Principles, Vol 2, p. 42. Allan on Lithotomy, p. 10.) The objections to cutting on the gripe, are; the impossibility of always dividing the same parts; for those which are cut will vary, according to the degree of force em- ployed in making the stone project in the perinEeum. When little exertion is made, if the incision be begun just behind the scro LITHOTOMY. 190 turn, the urethra maybe altogether detach- ed from the prostate: if the stone be much pushed out, the bladder may be entered beyond the prostate, and both the vesiculas serninales and vasa deferentia inevitably suffer. Lastly, if the parts are just suffi- ciently protruded, the bladder will be cut upon its neck, through the substance of the prostate gland. (Allan on Lithotomy. Burns , in Edinb. Surg. Journal, No. XIII. J. Bell , Vol. 2, p. 59.) The preceding dangers were known to Fabricius Hildanus, who attempted to obvi- ate them by cutting on a staff, introduced through the urethra into the bladder. He began his incision in the perinaeum, about half an inch on the side of the raphe ; and he continued the cut, inclining the knife as he proceeded towards the hip. He continu- ed to divide the parts till lie reached the staff ; after which he enlarged the wound to such an extent, as permitted him easily with a hook to extract the sione, which he had previously brought into the neck of the bladder, by pressure with the fingers in the rectum. (Burns.) In this way Mr. C. Bell has operated with success. (J. Bell.) The apparatus minor, as practised by Fabricius, with the aid of a staff, is certainly a very simple operation on children, and some judicious surgeons doubt the propriety of its present neglected state. You cut, says an eminent writer, upon the stone, and make of course, with perfect security, an incision exactly proportioned to its size. There is no difficult nor dangerous dissection; no gorget, nor other dangerous instrument, thrust into the bladder, with the risk of its passing betwixt that and the rectum ; you are performing, expressly, the lateral inci- sion of Raw and Cbeselden, in the most simple and favourable \yay. The prisca sim- plicity instrumentorum seems here to have been deserted, for the sake of inventing more ingenious and complicated operations. (J. Bell.) Celsus has delivered one memorable pre- cept in his description of lithotomy, ul pla- ga paulo major qurnn calculus sit ; and he seems to have known very well, that there was more danger from lacerating, than cut- ting the parts. The simplicity of the apparatus minor, however, formerly emboldened every quack to undertake its performance ; and as this circumstance was necessarily followed by the evils and blunders, unavoidably origina- ting from ignorance, and also diminished the emolument of regular practitioners, it be- came the grand cause of the downfall of this operation. (See Heister on this subject.) It was longer practised, however, than all the other methods, having been continued to the commencement of the 16th century ; and it was performed at Bourdeaux, Paris, and other places in France, on patients of all ages, by Raoux, even as late as 150 years ago. Frere Jacques occasionally had recourse to it ; and it was successfully exe- cuted by Ileister. ( Part 2, clftip. 140.) A modern author recommends it always to be preferred on boys under fourteen. (Allan, V • 12 .) APPARATUS MAJOR, So named from the multiplicity of instru- ments employed; or the Marian method, from having been first published by Ma- rianus Sanctus, in 1524, as the invention of his master, Johannes de Romanis. (See Marianus de lapide Vesiccc per mcisionem ex trahendo.) This operation, which came into vogue, as we have noticed, from avaricious causes, was rude, and painful in its performance, and very fatal in its consequences. The apology for its introduction was the decla- ration of Hippocrates, that wounds of mem- branous parts.are mortal. It was contended, however, that such parts might be dilated with impunity ; and on this principle of di- latation, Romanis invented a complex and dangerous plan of operating ; one very in- competent to fulfil the end proposed ; one, which, though supposed only to dilate, really lacerated the parts. (Burns.) The operator, kneeling on one knee, made an incision with his razor along the peri- naeum, on one side of th»* raphe ; and feel ing with his little finger for the curve of the staff, he opened the membranous part of the urethra ; and fixing the point of the knife in the groove of his staff, gave it to an assistant to hold, while he passed a probe along the knife into the groove of the staff, and thus into the bladder. The urine now flowed out. and the staff was withdrawn. The operator next took two conductors, a sort of strong iron probes ; one. named the fe- male conductor, having in it a groove, like one of our common directors ; the other the male conductor, having a probe point, corresponding with that groove. The groov- ed, or female conductor, being introduced along the probe into the bladder, the probe was withdrawn, and the male conductor passed along the groove of the female one, into the bladder. Then commenced the operation of dilating. The lithotomist took a conductor in each hand, and by making their shafts diverge, dilated, or, in plain lan- guage, tore open (he prostate gland. (J.Bell.) It would be absurd in me to trace the various dilating instruments contrived for the improvement of this barbarous operation , by the Colots, Marechal, Le Dran, Parfe, be. Among the numerous glaring objections to (he apparatus major, we need only notice the cutting the bulb of the urethra, not di- viding the membranous part of the urethra, nor the transversalis perinaii musele, which forms a kind of bar across the place where the stone should be extracted ; violent dis- tention of the membranous part of the ure- thra and neck of the bladder ; laceration of these latter parts; large abscesses, extrava- sation of urine, and gangrene ; frequent impotency afterward, and extensive fatali- ty. Bertraudi even saw the urethra and neck of the bladder torn from the prostate by the violerme employed in tins vile nv- LITHOTOMY. 191 hot] of operating. ( Operations de Chir. p. 169.) Pare, Le Dran, Le Cat, Mery, Mo- rand, Mareschal, Raw, and all the best sur- geons in Europe, most strangely practised this rash method, for two hundred years, till Fr&re Jaques, in 1697, taught at Paris the original model of lithotomy, as com- monly adopted at the present day. OF THE HIGH OPERATION'. This method of cutting for the stone was first published in 1556, by Pierre Franco, wbo, in his Treatise on Hernia, Ed. 1, says, he once performed it on a child with suc- cess, but discourages the farther practice of it. After him, Rossetus recommended it, with great zeal, in his book entitled Partus Cwsarius, printed in 1591 ; but he never performed the operation himself. Tolet mentions its having been tried in the H6lel Dieu, but without entering into the particu- lar causes of its discontinuance, merely says, that it was found inconvenient. About the year 1719, it was first done in England, by Mr. Douglas ; and after him, practised by others. ( Sharp’s Operations.) The patient being laid on a square table, with his legs hanging off, and fastened to the sides of it by a ligature, passed above the knee, his head and body lifted up a little by pillows, so as to relax the abdominal muscles, and his hands held steady by some assistants ; as much barley-water as be could bear, w'hich was often about eight ounces, and sometimes twelve, was injected through a catheter, into the bladder. The bladder being filled, an assistant, in order to prevent the reflux of the water, must grasp the penis, the moment the cathe- ter is withdrawn, bolding it on one side, in such a manner as not to stretch the skin of ^he abdomen ; then, with a round-edged knife, an incision, about four inches long, was made between the rfl(kti and pyramidal muscles, through the membrana adiposa, as deep as the bladder, bringing its extremity almost down to the penis; after this, with a crooked knife, the incision was continued into the bladder, and carried a little under the os pubis; and immediately upon the water’s flowing out, the forefinger of the left band was introduced, which directed the forceps to the stone. ( Sharp's Observations.) Sabatier condemns making the cut in the bladder from below upward, lest the knife injure the peritonaeum. {Med. Operatoire , , T. 3, p. 160.) Although this is one of the easiest, and to all appearance, the safest method of operating, several objections soon brought it into disuse. 1. The irritation of a stone often causes such a thickened and contracted state of the bladder, that this viscus will not admit of being distended so as to rise above the p?ibes. 2. If the ope- rator should break the stone, the fragments cannot be easily washed away, and remain- ing behind will form a nucleus for a future stone. 3. Experience has proved, that the high operation is very commonly followed by extravasation of urine, attended with suppuration and gangrenous mischief in the cellular membrane of the pelvis. This hap- pens because the urine more readily escapes out of the wound in the bladder, than through the urethra ; and also because when the bladder contracts, and sinks behind the os pubis, this wound ceases to be parallel to that in the linea alba and integuments, and becomes deeper and deeper. For the prevention of these ill consequences, says Sabatier, it will be in vain to make the pa- tient lie in a horizontal posture, and keep a catheter introduced, as Roussetand Morand recommended : experience evincing, that the bad efFects are neither less frequent, nor less fatal (See Medecine Operatoire, T. 3, p. 161, Edit. 2.) And Sir Everard Home confesses, that while the high operation for the stone had no other channel but the wound for carrying off the urine, it seemed to him a method which ought never to be adopted ; “ the urine almost always insinu- ating itself into the cellular membrane be- hind the pubes, producing sloughs, and con- sequently abscerses.” (On Strictures , Vol. 3. p. 359, 8vo. Land. 1S2I.) 4. The danger of exciting inflammation of the peritonaeum. 5. The injection itself is exceedingly pain- ful, and however slow the fluid be injected, the bladder can seldom be dilated enough to make the operation absolutely secure : and when hastily dilated (to say nothing of the possibility of" its bursting,) its tone may be destroyed. (See Sharp, Bilan , Sabatier , 4'C.) In many men, however, we know by searching, that the bladder is very large, so that there is no risk <4 meeting with it in a contracted state, and the objection is of no weight, when the bladder extends a consider- able way above the pubes, and will admit a large quantity of injection. Stones are some- times known to be of large size, and they arc less likely to be btoken in this, than any other mode of lithotomy, so that the objection of the difficulty «>f extracting small calculi and fragments is less forcible. Mr Carpue even declares, that if the stone should break, the particles can be extracted with much greater certainty, in less time, and with considerably less pain, than in the lateral operation, (History of the High Operation , p. 154.) I may add, that some judicious surgeons of the present day are decidedly of opinion, that when a stone in the bladder is known to be very large, no attempt ought ever to be made to extract it from the perinaeum. Professor Scarpa also declares, that the lateral operation should not be practised, when the calculus exceeds twenty lines in its small diameter. (See Memoir on the Cut- ting Gorget of Hawkins, p. 8, transl. by Briggs.) In such cases, it is true, the surgeon might do the lateral operation, and try to break the stone. But it is a question whether one ought not to prefer to this unpleasant, un- satisfactory proceeding, the high operation. I speak particularly ot cases, in which the stone is known to be of very large dimen- sions before any operation is begun Were LITHOTOMY 192 the lateral operation commenced, the stone, •f too large for extraction, must of course be broken ; for, it is then too late to adopt the high operation with advantage. That such things have been done, however, arid yet the patients escaped, is a truth, which cannot be denied. Deschamps mentions an in- stance, initwhich M. Lassus, after using Hawkins’s gorget, could not draw out the calculus, and he therefore immediately did the high operation, and the patient recover- ed. Indeed, the first example of the . high operation on record was done by Franco under similar circumstances, and the patient was saved. I have also heard of a modern French surgeon, who began with the lateral operation, but, finding a large calculus, end- ed with performing the high operation, with- out the least delay or hesitation : the patient died. Mr. Samuel Sharp, an excellent practical surgeon in his time, after noticing with great impartiality the objections which were then urged against the high operation says, that he should not be surprised, if hereafter it were revived and practised with success; an observation, which implied, that Mr. Sharp himself foresaw, that the method was capa- ble of being so improved, as to free it from its most serious inconveniences. In fact, since his time, various attempts have been made to introduce the high operation anew, and upon improved principles. Frere Come, i s particular, knew very well, that there were circumstances, as for instance, a calcu- lus above a certain size, disease of the ure- thra, or prostate gland, &lc., where the late- ral operation was liable to great difficulties and disadvantages, and where the high operation, if it could be perfected, would be a fitter and safer mode of proceeding. However, it was only in such cases, and not in all, that Frere C6me thought the method better than the lateral operation. He had also discernment enough to perceive, that it was extremely desirable to invent some means, whereby the painful and hurt- ful distention of the bladder, for the purpose of making this organ rise behind the pubes, would be rendered unnecessary; fit the same time, that some measure was adopted for letting the urine have a more depending outlet, than the wound in the hypogastric region. In the former editions of this dictionary, the error was committed of representing C6me to have cut the neck of the bladder, as well as its fundus ; a mistake, which I first became aware of upon the perusal of Mr. Carpue’s interesting work on lithotomy. The fact is, that Come did not wound the bladder in two places ; but ope- rated after the following .way : he first intro- duced through the urethra into the bladder a staff, which was then held by an assistant. An incision, an inch in length, was now made in the perinteum in the same direction, as in the lateral operation. Another incision was made in the membranous part of the urethra along the groove of the stalf, as fur as the prostate gland. A very deeply grooved director was then passed along the staff into the bladder, and the latter instru- ment was withdrawn. By means of the director, a sonde a dard , or kind of catheter furnished with a stilette, was now introduced into the bladder, and, when this had Ufeeu done, the director was taken out. An in- cision was then made, about three or four inches in length, just above the symphysis of the pubes, down to, and in the direction of the linea alba. A trocar, in which there was a concealed bistoury, was next passed into the linea alba, close to the pubes, and the blade of the knife then started from its sheath towards the handle of the instrument, while its other end remained stationary. In. this manner, the lower part of the linea alba was cut from below upwards, and an aper- ture was made, which was now enlarged with a probe-pointed curved knife, behind which a finger was kept so as to push the peritonaeum out of the way. Come then took hold of the sonde a dard with his right baud, and elevating its extremity, lifted up the fundus of the bladder, while with the fingers of his left hand he endeavoured to feel its extremity in the wound. As soon as the end of the instrument was perceived, it was taken hold of between the thumb and middle finger, the peritoneum was carefull }/ kept up out of the way, and the stilette was pushed by an assistant from within outwards, through the fundus of the bladder. The bladder being thus pierced, the operator in- troduced into a groove in the stilette a curved bistoury, with which he divided the front of the bladder, from above downwards, nearly to its neck. He then passed his fin- gers into the opening, and keeping up the bladder with them, withdrew the sonde a dard altogether. But, as it was useful that both his hands should be free, the bladder was prevented from slipping away by means of a suspensory hook held by an assistant as soon as the opening was found to be already ample enough, or had been enlarged to the necessary extent. Cdme next intro- duced the forceps, took out the stone, and passed a cannula, or elastic gum catheter through the wound in the perineeum into the bladder, so as to maintain a ready outlet for the urine, and divert this lluid from the wound in the bladder. In women, of course, the catheter was passed through the meatus urinarius. And, 1 ought here to observe, that C6me thought the high operation espe- cially adviseable for females, because his experience had taught him, that the division, or dilatation , of the meatus urinarius was generally followed by an incontinence of urine. (See JYouvclle Mbthode d'exlraire la Pierre de la Vessie par dessus le Pubis , fyc. S vo. Bruxelles , 1779.) Another modification of the high operation was suggested by Deschamps, who, instead of opening the membranous part of the urethra as C6me did, perforated the bladder from the rectum, and through the cannula of the trocar effected the same objects, which the latter lithotomist accomplished by means of the incision in the membranous part of the urethra. Of the two plans, that LITHOTOMY Revised by Gome is unquestionably the best, because not attended with a double wound of the bladder ; a thing which, I conceive, must always be highly objectionable. Dr. Souberbielle, who practices Come’s method, introduces a silver wire hrough the cannula of the sonde a dard , and passes it through the wound made in the tinea alba. The wire is then held while the sonde a dard is withdrawn, and a flexible gum-catheter is passed by means of the wire into the blad- der through the wound in-the membranous part of the urethra. The wire is now with- drawn, and the catheter is fixed with tapes, passed round the thighs and pelvis, and a bladder is tied to it for the reception of the urine. “ A piece of soft linen, half an inch wide, and six or eight inches long, is to be introduced, by means of a pair of forceps into the bottom of the bladder;” the object of which slip of linen is to carry off such urine, as may not escape through the cathe- ter. Lint and light dressings are applied, and a bandage round the abdomen. Great care is to be taken to keep the catheter per- vious, and, usually on the third day, the slip of lirftn may be taken out, and the wound closed with adhesive plaster. (See Carpue’s Hisiory of the High Operation , p.l 71, 172.) Sir Everard Home made trial of Dr. Sou- berbielle’s method in St. George’s Hospital, and though some difficulty and delay occur- red in the operation, on account of the stone .being encysted, the result was successful. Subsequently to this case, however. Sir Everard has invented and practised another method, which, as far as I can judge, is better than that of Come, or Souberbielle, though its principles are the same. When it is considered, that in the operation of these last lithotomists, the neck of the bladder is not opened, and the catheter enters that re- ceptacle through the prostatic portion of the urethra, it must be immediately obvious, that the incision in the perinaeum cannot answer any material object, because a tube may be placed in the same position by passing it through the urethra from the orifice in the glans. The retainer, or bracelet, invented for keeping the catheter in the bladder, in cases of enlargement of the prostate gland, seemed to Sir Everard Home peculiarly ap- plicable to the high -operation, since it keeps the tube steadily in the natural canal, and * renders the wound in the perinaeum unneces- sary. Bracelets, for this purpose, extremely elastic, and producing no irritation, are sold by Mr. Weiss, of the Strand. They are furnished with small rings, to which the outer end of the catheter is fixed by means of string. Sir Everard Home performed his new operation, for the first time, in St. George’s Hospital, on the 26th of May, 1820. An in- cision was made in the direction of the linea alba, between the pyramidales muscles, be- ginning at the pubes, and extending four inches in length : it was continued down to the tendon. The linea alba was then pierced close to the pubes, and divided by a probe- pointed bis tour v to the extent of three Vol. I Ft 25 inches. Tfle pyramidales muscles had a por- tion of their origin at the symphysis pubis detached, to make room. When the finger was passed down under the linea alba, the fundus of the bladder was felt covered with loose, fatly, cellular membrane. A silver catheter, open at the end, was now passed along the urethra into the bladder, and when the point was felt by the finger in the wound, pressing up the fundus, a stilet, that had been concealed, was forced through the coats of the bladder, and followed by the end of the catheter. The stilet was then withdrawn, and the opening, through the fundus of the bladder, enlarged towards the pubes, by a probe-pointed bistoury, suffi- ciently to admit two fingers, and then the catheter was. withdrawn. The fundus of the bladder was held up by one finger, and the stone examined by the forefinger of the right hand. A pair of forceps, with a net attached, was passed down into the bladder, and the stone directed into it by the finger : the sur- face being very rough, the stone stuck upon the opening of the" forceps, and being re- tained there by the finger, was extracted. A slip of linen had one end introduced into the bladder, and the other was left hanging out of the wound, the edges of which were brought together by adhesive plaster. A flexible gum catheter, without the stilet, was passed into the bladder by the urethra, and kept there by an elastic retainer surrounding the penis. The patient was put to bed, and laid upon his side, in which position the urine escaped freely through the catheter.” As no blood had been lost i:i the operation, twelve ounces were taken from the arm. iup next day the slip of linen was with- drawn, as useless and irritating, the catheter, while pervious, preventing any urine from escaping by the wound- Sir Everard thinks, that in future the linen nbed only be left in the external wound, so as to prevent col- lections of matter, and carry off any urine, which may issue from the opening in the bladder, when the catheter happens to be stopped up. For this operation, Sir Eve- rard particularly recommends catheters, with their insides polished like their outsides, in order that they may better resist the effects of the urine. Suffice it to add, with, respect to the above case, that the boy soon recovered, the bladder having resumed its healthy functions in ten days, although the calculos was of the roughest possible kind. Sir Everard Home has repeated his new method on a gentleman, who went out in his carriage, with the external wound con - pletely healed, on the 14th day after the ope- ration. The only particulars, which need here be noticed, in regard to the latter case, are, that some difficulty was experienced in bringing the point of the catheter forwards toward the pubes, and the slit in the front of the instrument made it so incapable of bear- ing lateral -motion, that the two sides were twisted over one another. (On Strictures, Vol. 3, p. 359, Svo. Load. 1820.) Whoever follows this method of ooeratin*** should always be« .provided with 1 severed LITHOTOMY T94 tubes and stilets, of different lengths and curvatures ; for, in the only case, in which I have seen the operation attempted, the ex- tremity of the catheter could not be made to project the fundus of the bladder towards the pubes, and, after long-protracted endea- vours had been made to bring the end of the instrument upwards and forwards, the tube broke, and the operation was left unfinished. The impression upon my mind was, that no resistance of the bladder could account for what happened, and that the fault lay in the instrument itself, which should have been exchanged for anotherof more suitable form, as soon as it was found to be inapplicable. And, l believe, that if attention be paid to this suggestion of always having at hand a suf- ficient number of tubes and stilets of differ- ent lengths and curvatures, Sir Everard Home’s new method will be the best modifi- calion of the high operation yet proposed. The slip of linen, however, I think is more likely to do harm by its irritation, than any good, as a conductor of the urine or matter out the wound. At all events, as Sir Eve- rard has observed, it should never be passed into the bladder itself. Whenever I am asked my opinion, respecting the preference, which should be given to the high operation, as a general practice, I venture no further than to express a favourable opinion of it for cases, in which the calculus is known be- forehand to be of very large size, or the urethra and prostate gland are diseased. The reasons urged by Mr. Carpue, in favour of a preference to the high operation in most cases, are : 1. Because, it is generally performed in less time; a point, which may be disputed, though it is perhaps not worth con- testing, since the danger of an operation can- not always be truly estimated by the length of time, which the patient remains in the operating room, slow and gentle proceedings sometimes contributing to his safety. 2. There is less pain ; a remark, the justness of which must depend, perhaps, upon the manner in which each operation is done. 3. There is no fear of a fatal hemorrhage ; a consideration, which I admit is one good reason in favour of the high operation ; though the lateral ope- ration is only subject to risk of hemorrhage, when the incisions are directed in a manner not sanctioned in this dictionary. 4. There is no division of the prostate and inferior part of the bladder : no, but there is one of the fundus, so that perhaps on this point the two operations stand upon an equality, As for ‘there being no danger in the high operation of wounding the rectum, it is undoubtedly an advantage, though the accident, as far as L have seen, is not followed by any serious consequences, and can only happen from inattention to rules easily followed. 5. The stone, if of a cer- tain size, cannot be extracted by the lateral operation, but admits of being so by the high operation. Of all the reasons for the latter practice, this appears to me the strongest, with the exception perhaps of disease in the urethra and prostate. 6. A small stone is more readily discovered ifi this method, than in the lateral operation : a point which i consider questionable, and at all events, not sufficiently important to form a ground for the high operation. 7. If a stone breaks, the particles can be extracted with more certainty, than in the lateral operation : on this question authors differ. 8. The high operation enables the surgeon to remove encysted calculi with greater ease : a reason which may perhaps be generally true, but which is somewhat weakened by the consi- deration that encysted calculi are not very frequent. Mr. Carpue allows, that the high operation should not be selected when the patient is corpulent, and the bladder is thick- ened and diseased, so that its fundus cannot be raised above the pubes. (See Hist, of the High Operation, p. 173, 8 vo. Lond. 1819.) As it is not my object to discourage the practice of the high operation, under the par- ticular circumstances which have been speci- fied, I decline entering into any strict con sideration of the inconveniences to which this method is exclusively subject, especially, the greater vicinity of the wound to the peritoneum and small intestines, and the division of that membrane and protrusion of the viscera ; accidents, which w ill be found by any body, who chooses to look over the cases on record, not to have been unfre- quent. On the contrary, as I believe this method is advantageous in certain cases, the recent attempts to bring it to greater perfec- tion give me sincere pleasure. In December, 1818, Mr. Kirby, of Dublin, performed the high operation for the extrac- tion of an elastic gum catheter, which had slipped into the bladder through the cannula of a trocar, with which paracentesis had been performed. No contrivance was found necessary for lifting up the fundus of the bladder. The puncture, already made, was enlarged, and after the operation was fin- ished, a catheter was placed in the wound, but was withdrawn on the 4th day, as the urine passed out by the side of it. The case terminated well. (See Kirby's Cases, p. 92, tyc. 8 vo. Dublin , 1819.) LATERAL OPERATION. So named from the prostate gland, and neck of the bladder, being laterally cut. From some quotations made by Mr. Car- pue from the works of Franco, it appears clear enough, that the latter w r as not only the inventor of the lateral operation, but that he placed his patients in the position adopted at the present time, used similar in- struments to those now employed, (except- ing that his gorget bad no sharp side) and made the same incisions. Now, as this claim of Franco to an invention of such import- ance had been nearly, or quite forgot, when Mr. Carpue’s work made its appearance, the latter gentleman deserves much praise for reminding (he profession of what may be due to the memory of an old surgeon, whose name must flourish, as long as the history of the rise and progress of surgery isinterestingto mankind. But, though Franco appears proba- bly to havej*ractiscd the lateral operation, or LITHOTOMY. J95 something very much like it, he never esta- blished the method as a permanent improve- ment of surgery, which measure was left to be completed long afterward by ari ecclesiastic, who called himself Frere Jacques : he came to Paris in 1697, bringing with him abun- dance of certificates of his dexterity in ope- rating ; and making his history known to the court and magistrates of the city, he got an order to cut at the H6tel Dieu, and the Cha- rity, where he performed this operation on about fifty persons. His success did not answer the promises which he had made, and from that time his reputation seems to have declined in the world, if we may give credit to Dionis, who has furnished us w ith these particulars. — ( Sharp's Operations.) Frere Jacques used a large round staff With- out a groove, and when it was introduced into the bladder, be depressed its handle, with an intention of making the portion of this viscus, which he wished to cut, approach the periuaeum. He then plunged a long dagger-shaped knife into the left bip, near the tuber ischii, two finger-breadths from the periuaeum, and pushing it towards the blad- der, opened it in its body, or as near the neck as he could, directing his incision up- ward from the anus. He never withdrew his knife, till a sufficient opening bad been made for the extraction of the stone. Some- times he used a conductor to guide the for- ceps, but more commonly directed them with his finger, which he passed into the wound after withdrawing the knife. When he had hold of the stone, he used to draw it out in a quick rough manner, heedless of the bad coiisequences. His only object was to get the stone extracted, and he disregarded every thing else ; all preparatory means, ail dressings, all after-treatment. (Allan, p. 23.) Totally ignorant of anatomy, and thus rude and indiscriminate in practice, Frere Jacques soon sunk into disrepute. However, there were several eminent surgeons, who conceived, from considering the parts which be cut, that his method might be converted into a most useful operation. ( Sharp's Ope- rations.) The principal defect in his first manner of cutting, was the want of a groove in his staff, which made it difficult to carry the knife into the bladder. At length, Frere Jacques was prevailed upon to study anatomy, by which his judgment being improved, he readily embraced several improvements, which were suggested to him. Indeed, we are informed that he now succeeded better, and knew more, than is generally imagined. Mr. Sharp says, that when he himself was in France in 1702, he saw a pamphlet, published by this celebrated character, in which his me- thod of operating appeared so much impro- ved, that it scarcely differed from the practice of that time. Freire Jacques had learnt the necessity of dressing the wound after the operation, and had profited so much from the criticisms of Mery, Fagon, Felix, and Hunauld, that he then used a staff with a groove, and what is more extraordinary, had cut thirty-eight patients successively, without losing one. (Sharp's Operations.) In short, as a modern writer has observed, he lost fewer patients than we do at the pre- sent day, in operating with a gorget. He is said to have cut nearly 5000 patients in the course of his life, and though persecuted by the regular lithotomists, he was imitated by Marechal at Paris, Raw in Holland, and by Bamber and Cheselden in England, where his operation was perfected. (Allan.) For a particular history of Frere Jacques, and his operations, Allan refers us to Bus- siere's Letter to Sir Hans Sloane , Philos. Trans. 1699. Observations sur la Mani&re de tailler dans Us deux Sexes, pour V Extraction de la Pierre , praiiqu6e par F. Jacques , par J. Mery. Lister's Journey to Paris in 1693. Cours d' Operations de Chirurgie , par Dionis. Garengeot Traiti des Operations, T. 3, Ma- raud, Opuscule Chirurgie, Part 2. Among the many who saw Fre e Jacques operate, was the famous Professor Raw, who carried his method into Holland, and practi- sed it with amazing success. He never pub- lished any account of it himself, though he admitted several to his operations; but after his death, his successor Albums, gave the world a very circumstantial detail of all the processes, and mentions, as one of Raw’s improvements, that he used to open the blad- der, between its neck and the ureter. But either Albinus, in his relation, or Raw him- self in his supposition, w’as mistaken ; since it is almost impossible to cut the bladder in that part upon the common staff, without also wounding the neck.” (Sharp in Opera- tions and Critical Inquiry.) Raw’s method was objectionable, even when accomplished, as the urine could not readily escape, and became extravasaied around the rectum, so as to produce terrible mischief. There is little doubt, that Raw’s really successful plan was only imitative of Frere Jacques’s second improved one, though he was not honourable enough to confess it, (See Ferhius de Culculo Vcsicce .) Dr. Bamber was the first man in England, who made a trial of Raw’s method on the living subject, which he did in St. Bartholo- mew’s Hospital. Cheselden, who had been in the habit of practising the high operation, giadly abandoned it, on receiving the ac- count of Raw’s plan and success, and a few days after Bamber, he began to cut in tin’s way in Si. Thomas’s Hospital. Cheselden used at first to operate in -the following manner. The patient being pla- ced, and tied much in the same way, as is done at this day, the operator introduces a hollow grooved steel catheter into the blad der, and with a syringe, mounted with an ox’s ureter, injects as much warm water into it, as the patient can bear without pain. The water being kept from running out by a slip of fiannel tied round the penis, the end of the catheter is to be held f»y an assistant, whose principal care is to keep it from rising, but not at all to direct the groove to the place where the incision is to be made. With a pointed convex-edged knife, the LITHOTOMY operator beginning about an inch above the anus, on 1 he left side of the raphe, between the accelerator u rinse, and erector penis, makes an incision downwards, by the side of the sphincter ani, a little obliquely outward.*? ns it descends, from two and a half to four inches in length, according to the age of the patient, or size and structure of the parts. This incision he endeavours to make aii at one stroke, so as to cut through the skin, tut, and all, or part of the levator ani, which lies in his way. This done, he passes his left fore-finger into the middle of he wound, in order to press the rectum to one side, that it may be in less danger of being cut ; and taking a crooked knife in his other hand, with the edge on the concave side, he thrusts the point of it through the wound, close by his linger, into (he bladder, between the ve- sicula setninalis and os ischium of the same side. This second incision is continued up- wards, till the point of the knife comes out at the upper part of the first. The incision be- ing completed, the operator passes his left fore-finger through the wound into the blad- der, and having felt, and secured the stone, he introduces the forceps, pulls out his finger, and extracts the stone. As the bladder was distended, Cheselden thought it unnecessary to cut on the groove of the staff, and that, as this viscus was suffi- ciently pressed down by the instrument, the forceps could be very well introduced with- out the use of any director, except the finger. ( Postscript to Douglas's History of the Lateral Operation , 1726.) With respect to this first of Cheselden’s plans, Sharp says, the operations were ex- ceedingly dexterous ; but the wound of tile bladder retiring back, when it was empty, did not leave a ready issue for the urine, which insinuated itself among the neighbour- ing muscles and cellular substance, and four out of the ten patients on whom the operation was done perished, and some of the others narrowly escaped. ( Sharp's Operations.) Cheselden, finding that he lost .-<> many patients in imitating Raw*, according to the directions given by Albinus, began a new manner of operating, which he thus de- scribes : “ I first make as long an incision as 1 well can, beginning near the place where the old operation ends, and cutting down between the rnusculus accelerator urina? and erector penis, and by the side of the intesti- num rectum : 1 then feel for the staff, and cut upon it the length of the prostate gland straight on to the bladder, holding down the gut all the while with one or two fingers of my left hand.” {Anatomy of the Human Body , Edit. 1730.) Jt deserves remark, that it was Cheselden’s second manner of cutting, which ivasdescri bed in the Opuscules de Chirurgie , of Morand, who was deputed, and had Ins expenses de frayed by the Royal Academy of Sciences in Paris, to come over to England, and learn from Mr. Cheselden himself, his way of ope- rating for the stone ; and, accordingly, we find, that most French authors, taking their ac- count from Morand, describe Cheselden ’s se- cond, not his third operation, as that which he invented, and bears his name. But, that Mr Cheselden never resumed his second manner of cutting may be inferred from his continuing to describe the third only in all (he editions of his anatomy published after 1730. {See anote by J. Thomson , M. D. an- nexed to his new edition of Douglas's Appen- dix. Edinb 1808.) The insirumenis which Cheselden employ- ed in his third, and most improved mode of cutting for the stone, were a stall', an incision knife, a gorget, a pair of forceps, and ga crooked needle carrying a waxed tiiread. The patient being placed on a table, his wrists are brought down to the outsides of his ankles p and secured there by proper bandages, his knees having first been bent, and his heels brought back near his buttocks. Cheselden used then to take a catheter, first dipped in oil, and introduce it into the bladder, where having searched for, and discovered the stone, he gave the instru- ment to one of his colleagues, whom he de- sired to satisfy himself, whether there was a stone, or not. The assistant, standing on his right hand, held the handle of the staff be- tween his fingers and thumb, inclined it a little towards the patient's right thigh, and drew the concave side close up to the os pu- bis, in order to remove the urethra as far as possible from the rectum. The groove of the staff being thus turned outwardly and laterally, Cheselden sat down in alow chair, and keeping the skin of the perinaeum steady with the "thumb and fore- finger of his left hand, he made the first or outward incision, through the integuments, from above downwards, beginning on the left side of the raphe, between the scrotum arid verge of the anus, almost as high up as where the skin of the perinaeum begins to form the bag containing the testicles. Thence he continued the wound obliquely outwards, as low down as the middle of the margin of the anus, at about half an inch distant from it r and consequently, beyond the tuberosity of the ischium. He was always careful to make this outward wound as large as he could with safety. Having cut (he fat rather deeply, especially near the rectum, he used to put his left fore-finger info the wound, and keep it there till the internal incision was quite finish- ed ; first to direct the point of his knife into the groove of the staff, which he now felt with the end of his finger • and secondly, to hold and prevent the rectum from being wounded, by the side of which his knife was to pass. This inward incision Cheselden made with more caution, than the former. H is knife first entered the groove of the ros- trated, or straight part of the staff, through the side of the bladder, immediately above the prostate, and its point was afterward brought along the same groove in the direc- tion downwards, and forwards, or towards himself. Cheselden thus divided that part of the sphincter of the bladder, which lay upon the prostate gland, of which he next cut the outside of one half obliquely, accord- ing to the direction and whole length of the tlTHOIOMY. 197 urethra within it, and finished tlie internal in- cision, by dividing the membranous portion of the urethra, on the convex part of his staff’. A sufficient opening being made, Che- selden used to rise from his chair, bis finger still remaining in the wound. Next he put the beak of his gorget in the groove of the staff', and then thrust it into the bladder. The staff was now withdrawn, and while he held the gorget with his left hand, lie intro- duced the forceps with the Hat side upper- most, with great caution along the concavity of the gorget. When the forceps was in the bladder, he withdrew the gorget, and taking hold of the two handles of the forceps with both his hands, he searched gently for the stone, while the blades were still kept shut. As soon as the calculus was felt, the forceps Was opened, and an attempt made to get the lower blade under the stone, in order that it might be more conveniently laid hold of. This being done, the stone was extracted with a very slow motion, in order to give the parts time to dilate, and the forceps was gently turned in all directions. When the stone was very small, and did not lie well in the forceps, Cheselden used to withdraw this instrument, and introduce his finger into the bladder, for the purpose of turning the stone, and disengaging it from the folds of the lining of the bladder, in which it was sometimes entangled. Then the gorget w as passed in again on the upper side of his finger, and turned as soon as the fatter was pulled out. Lastly ; the forceps was introduced, and the stone extracted. With the view of hindering a soft stone from breaking during its extraction, Chesel- den used to put one or more of his fingers between the branches of his forceps, so as to prevent any greater pressure upon it, than what was just necessary to hold it to- gether. But when it did break, or there were more calculi than one, he used to extract the single stones, or fragments, one after another, repeating the introduction of his fingers and forceps, as often as there was occasion. Cheselden took care not to thrust the forceps so far into the bladder as to bruise or wound its opposite side; and he was equally careful not to pinch any folds of its inner coat. In this w ay, Cheselden saved 50 patients out of 52, whom he cut successively in St. Thomas’s Hospital. (Ap- pendix to the History of the Lateral Opera- tion, by J. Douglas. 1731.) Cheselden, with all the enthusiasm of an inventor, believed, that he had discovered an operation, which was not susceptible of improvement ; yet, he himself changed the manner of his incision not less than three times, in the course of a few years. 1st, He cut into the body of the bladder, behind the prostate, when he imitated Raw. 2dly, He cut another part of the bladder, viz. the neck and the thick substance of the pros- tate ; this is his lateral mode of incision. 3dly, He changed a third time, not the es- sential form of the incision, but the direc- tion, in which he moved the knife ; for in his first operation, when imitating the sup- posed operation of Raw and Frcre Jacques, he struck his knife into the body of the bladder, betwixt the tuber ischii and the vesiculac seminales, and all his incision lav behind the prostate gland. In this second operation, he pushed his knife into the membranous part of the urethra, imme- diately behind the bulb, and ran it down through the substance of the gland ; but his incision shopped at the membranous *part, or body, of the bladder. But in his third operation, after very large external inci- sions, he passed his knife deeply into the great hollow under the tuber ischii, entered it into the body of the bladder immediately behind the gland, and drawing it towards himself, cut through the whole substance of the gland, and even a part of the urethra, “ cutting the same parts the contrary way.” By carrying the fore-finger of the left hand before the knife, in dissecting towards the body of the bladder, he protected the rec- tum more perfectly, than he could do in running the knife backwards along the groove of the staff’; and by striking his knife into the body of the bladder and drawing it towards him, through the whole thickness of the gland, he was sqre to make an ample wound. (J. Bell's Principles of Surgery, Vol. 2, Part 1, p. 152.) LATERAL OPERATION AS PERFORMED AT TUB PRESENT DAV WITH CUTTING GORGETS. The gorget has the same kind of form as one of the instruments used by F. Colot and others in the performance of the appa- ratus major, and the common opinion, that the conductor of Hildanus was the first mo- del of it, is not exactly true ; but it differs from the instruments employed by these older surgeons in having a cutting edge. Sir Cesar Hawkins thought that, when its right side was sharpened into a cutting edge, it might be safely pushed into the blad- der, guided by the staff, so as to make the true lateral incision in the left side of the prostate gland more easily, and with less risk of injuring the adjacent parts, than Cheselden could do with the knife ; and surgeons were pleased with a contrivance, which saved them from the responsibility of dissecting parts, with the anatomy of which all were not equally well acquainted. (J. Bell. Allan.) As Scarpa observes : To render the exe- cution of the lateral operation easier to surgeons of less experience than Chesel- den, was the motive which induced Haw- kins to propose his gorget. He thought, that two great advantages would be gained by the use of this instrument ; one of exe- cuting invariably the lateral incision of Cheselden ; the other, of constantly guard- ing the patient through the whole course of the operation, from injury of the rectum, and of the arteria pudica profunda. The utility of the latter object (says Scarpa) cannot be disputed, as it is evident, that the convexity of the director of the instrument de- fends the rectum from injury, and that its cutting edge not being inclined horizontally. 198 LITHOTOMY. inwards iitc tuberosity and ramus of the ischi- urn, but turned upwards in the direction of the longitudinal axis of the neck of the urethra , cannot wound the pudic artery. But, with respect to the first advantage, or that of executing precisely the lateral incision of Cheselden, it must be admitted that it does not completely fulfil the intention which he |)roposed, not only on account of the cutting edge of his instrument not being raised enough above the level of the staff, to pene- trate sufficiently the substance of the pros- tate gland, and consequently to divide it to a proper depth ; but, because being too much turned upwards at that part of it, which is to lay open the base of the pros- tate gland, it does not divide it laterally, but rather at its upper part, towards the summit of the ramus of the ischium, and the arch of the pubes ; an opening, of all others in the perinaDum, the most confined, and presenting the greatest impediment to the passage of the stone from the bladder. The breadth of the point of the director is, be- sides, so disproportionate to the diameter of the membranous part of the urethra, that, from the great resistance with which it meets, the instrument may easily slip from the groove of the staff, and pass between the bladder and rectum, a serious accident, which has very often happened even in the hands of experienced surgeons. Scarpa considers all the modifications of Hawkins’s gorget, proposed by B. Bell, Desault, Cline, and Cruikshanks, as deteri- orations of the original instrument. B. Bell (he observes) has diminished the breadth of the director, but has given the cutting edge an horizontal direction. The horiz >n- tal direction of the cutting edge is also pre- ferred by Desault, Cline, and Cruikshanks ; but they have enlarged the director, and flattened the part which was previously concave. Aware of the danger of wound- ing the pudic artery, by the horizontal di- rection of the gorget, they direct the handle of the staff to be inclined towards the pa- tient’s right groin, and the gorget to be pushed along it, inclined in such a manner, that its obtuse edge may be directed towards the rectum, and its cutting edge placed at a sufficient distance from the tuberosity and ramus of the ischium to avoid wounding the artery. Scarpa contends, however, that it is difficult to give a proper degree of obliquity to the staff, and that such inclina- tion of the instrument must be incommo- dious, arbitrary, and unstable, in comparison with that position of it, in which the handle of the staff is held in a line perpendicular to the body of the patient, and its concavity placed against the arch of the pubes ; on which stability of the instrument (says Scar- pa) the safety and precision of the lateral operation depend. According to this emi- nent professor, the defects of Hawkins’s original gorget arise from the excessive breadth of the director, particularly at the point ; the want of sufficient elevation of the cutting edge, above the level of the groove of the staff, and the uncertain incli- nation of the edge to the axis of the urethra and prostate gland. The cervix of the ure thra, in a man between thirty and forty years of age, is only three lines in diameter at the apex of the prostate gland, four lines in its centre, and five near the orifice of the bladder. The apex of the prostate gland is rather more than two lines in thickness, the body or centre four, and the base six, and sometimes eight, which surrounds the orifice of the bladder. In an adult of middle sta- ture, from eighteen to twenty years of age, the thickness of the base of the prostate gland is about two lines less, compared with that of a man of forty, and of a large size. The precise line in which the lateral incision of the prostate gland should be made in an adult, (says Scarpa) is found to be inclined to the longitudinal axis of the cervix of the urethra, and of the gland itself, at an angle of 69°. Now, from these data, drawn from the structure of the parts, Scarpa makes the director of his gorget only four lines broad, and two deep ; the breadth decreasing at the beak. The cutting edge of the instru- ment is straight near its point, but gradu- ally rises, and becomes convex above the level of the staff, so that its greatest con- vexity is seven lines broad. Lastly ; the inclination of the cutting edge to the lon- gitudinal axis of the director, is exactly at an angle of 69° ; that is to say, the same as the left side of the prostate gland to the longitudinal axis of the neck of the urethra. (See Scarpa’s Memoir on Haw- kins’s Gorget; transl. by Mr. Briggs , p. 12, 17.) For nearly twenty years past, the instru- ment-makers in London have been in the habit of selling a gorget, which Mr. Aberne- thy first had constructed, and which in the particularity of having its cutting edge turn- ed up at an angle of 45°, bears much analo- gy to the instrument lately recommended by Scarpa. The cutting edge is straight, and that useless and dangerous part of a gorget, sometimes called the shoulder, is re- moved. Admitting that the principles of the lateral operation as inculcated by Scar- pa, are correct, and of which 1 shall present- ly speak, it appears to me, that Mr. Aberne- thy’s gorget is far preferable to that very re- cently proposed by Scarpa. Its edge is not so immoderately turned up, and it will enter with more ease, and less risk of slipping from from the staff, because it has not any pro- jecting shoulder, which, while the staff is firmly held with the beak of the gorget in it, can have no other effect but that of obstruct- ing the passage of the last instrument. Gorgets, which cut on both sides, have also been sometimes employed in England, and as a larger opening can be obtained by them, even without trespassing the limits of the incision, fixed by Scarpa, that is to say, without cutting any part of the body of the bladder, they appear to promise utility, es- pecially when the stone is suspected to be large. However, they are less used now, than they were some years ago, when Sir Astley Cooper employed them in Guv’s* Ho i: LITHOTOMY. pital ; but I aui unacquainted with the par- ticular reasons of this change. Some criticisms on Scarpa’s method of operating, and a few remarks on the size and direction of the lateral incision, will be found in a subsequent section of the present article. As inflammation of the bladder and peri- tonaeum is the principal danger of this ope- ration, and, under an equal degree of injury and violence, is most likely to happen in a plethoric subject, it ha3 been a question, whether venesection should not be practised a day or two before the patient is operated upon, supposing that his age and weakness form no prohibition. The chief reason, which prevents the common observance of this practice is, that a great deal of blood is sometimes lost in the operation itself. But when this has not happened, and the patient is young and strong, and particularly when the operation has been tedious, and the bladder has suffered a good deal, I am dis- posed to think very favourable of the rule, which is followed by many surgeons, of bleeding the patient as soon as he is put to bed, and recovered from the first depressing effects of the operation. An opening medi- cine should also be given*the day before the patient is cut, and a clyster injected a cou- ple of hours before the time fixed upon for the operation, in order to empty the rectum, and thus diminish the chance of its being ■wounded. As it is advantageous to have the bladder somewhat distended, the patient should be requested to retain his urine a certain time before being cut. Formerly, a jugum penis was sometimes used for confining the urine in the bladder ; but, since my entrance into the profession, I have never heard of this contrivance being employed. Before the operation, the following instru- ments should all be arranged ready on a table : a staff of as large a diameter as will easily admit of introduction, and the groove of which is very deep, and closed at the ex- tremity. A sharp gorget, with a beak nicely and accurately adapted to the deep groove of the preceding instrument, so as to glide easily and securely. A large scalpel for making the first incisions. Forceps of va- rious sizes, for extracting the stone. A blunt-pointed curved bistoury for enlarging the wound in the prostate, if the incision of the gorget be not sufficiently large, as the parts should never be lacerated. A pair of Le Cat’s forceps with teeth for breaking the stone, if too large to come through any wound reasonably dilated. A syringe for washing out clots of blood, or particles of the stone. A scoop for the removal of small calculi or fragments. Two strong garters, or bands, with which the patient’s hands and feet are tied together. The curvature of the staff is a matter of considerable importance ; because the di- rection of the incision through the prostate gland and neck of the bladder is partly de- termined by it. The French surgeons, con- vinced of the advantage of introducing the 199 gorget in the direction of the axi3 of the bladder, always use a staff, which is much more curved than what English surgeons employ. (See Roux, Voyage fait a Londres en IS 14, ou Par allele de la Chir. Angloise , <£'C. p. 319 ) But, I am inclined to believe with Scarpa, that, upon the whole, it is best to let the curvature of the staff correspond exactly to that of the axis of the neck of the urethra and prostate gland. ( Memoir on Hawkins's Gorget, <^c. p. 17.) After introducing the staff, and feeling that the stone is certainly in the bladder, the patient is to be secured in the same position, as was described in the account of Chesel- den’s latest method of operating. The assistant, holding up the scrotum with his left hand, is with his right to hold the staff, inclining its handle towards the right groin, so as to make the grooved con- vexity of the instrument turn towards the left side of the perinaeum. Some operators, also, like the assistant to depress the handle of the staff towards the patient’s abdomen, in order to make its convexity project ia the perinaeum, while others condemn this plan, asserting, that it withdraws the instru- ment from the bladder. {Allan, fyc.) Professor Scarpa disapproves of inclining the handle of the staff towards the patient’s right groin, ( p . 15.) and he expressly recom - mends this instrument to be held firmly against the arch of the pubes, in a line per- pendicular to the body of the patient, so that the convex part of the director may be placed towards the rectum, and take the exact course of the axis of the neck of the urethra and prostate gland. (P. 20.) This position of the staff is the firmest and most commodious to the surgeon, and Scarpa maintains, that on such stability of the instru- ment the safety and precision of the lateral operation depend. (P. 15.) The first incision should alw r ays com- mence below f the bulb of the urethra, over the membranous part of this canal, at the place, where the operator means to make bis first cut into the groove of the staff, and the cut should extend at least three inches, ob- liquely downward, to the left of the raphe of the perinaeum, at equal distance from the tuberosity of the ischium and the anus. In a large man, the first cut should pass the anus an inch and a half or more ; for it is a general rule in surgery to make free exter- nal incisions, by w hich the surgeon is ena- bled to conduct the remaining steps of his operation with greater facility, and nowhere is it so necessary, as where a stone is to be extracted. {Allan.) That excellent surgi- cal writer, Callisen, lays it dow r n as a rule to be observed in the lateral operation, that • the incision ought not to extend to such parts as can make no impediment to the extraction of the stone ; and therefore, (says he) the bulb , and that part of the urethra, vjhich is sur- rounded by the corpus spongiosum, should never be cut. Only those parts ought to be divided, which firmly resist the safe intro- duction of instruments into the bladder, and the extraction of the- stone. Hence, the in- LITHOTOMY. StJO teguments must be opened by an ample in- cision, and the membranous part of the ure- thra, transversales perinaei muscles, levater uni, and prostate gland, be properly divided. ( Callisen , Systema Chirurgiee Ilodicrnce, Pars 2, p. 655.) Like Scarpa, however, he is fearful of making a free cut through the neck of the bladder, and in lieu of doing so, prefers a slow and cautious dilatation of the parts. When the external cut through the integuments has been executed, the next object is to divide the transversales perinsei muscles, which stand, like a bar, across the triangular hollow, out of which alone the stone can be easily extracted. A part of the membranous portion of the urethra, adjoin- ing the prostate gland, is next to be laid open ; but an extensive cut through it, as far forward as the bulb, is quite unnecessary, because it will not at all facilitate the pas- N sage of the stone outward. Having placed the beak of the gorget in the groove of the staff, the operator takes firm hold of the latter instrument with his left hand, raises its handle from the abdo- men, so that it may form nearly a right an- gle with the body, and stands up. Before attempting to push the gorget into the blad- der, however, he should slide it backwards and forwards, with a wriggling motion, that he may first be sure of its beak being in the groove of the staff. The bringing forward of the handle of the latter instrument, so as to elevate its point, before introducing the gor- get into the bladder, is also considered of great importance : for it is by this means, that the gorget is introduced along the groove of l he staff in the axis of the blad- der, the only direction unattended with risk of wounding the rectum. In fact, the gor- get should be introduced nearly in a direc- tion, corresponding to a line drawn from the os coccygis to the umbilicus. It is ob- vious, however, that the degree in which the handle of the staff' should be depressed, must depend very much upon the curvature of i he instrument. The utmost attention to the ride last no- ticed is especially necessary, when a staff with a groove not closed at the end is em- ployed. The neglect of it in this case might make the operator cut the bladder with the gorget in several places, as has actually happened, as we learn from the observations of Mr. B. Bell. But since the gorget, when introduced as nearly as possi- ble in the axis of the bladder, may transfix and otherwise injure this organ, if introdu- ced either too far, or at all beyond the ex- tremity of the staff, I am decidedly of opi- nion that every surgeon, who chooses to perform the lateral operation with a gorget, should employ a staff, the groove of which is closed at the extremity, as is invariably done in France, and is expressly enjoined by Professor Scarpa. (See Sabatier's Mt- ilecine Optroioire, T 3 ,p. 223. Edit. 2; and Scarpa's Memoir on Hawkins's Gorget, p. 18, <^c.) There can also be no doubt of the prudence of endeavouring to have only a fixed and limited length of the stafLin the bladder. Scarpa specifies an inch and a half as the proper distance to which the end of the staff’ should enter the bladder. How- ever, as it is known, that this distinguished Professor is an advocate for a very limited incision, and that consequently, he would not require the staff to extend further than an inch and a half into the bladder, I infer that operators, who prefer making a freer opening, must use a staff' that reaches into this viscus rather further. Much, however, will depend upon the kind of gorget em- ployed, particularly its breadth. As soon as the gorget is introduced, the staff is to be withdrawn. Some operators next pass the forceps alopg the concave surface of the gorget into the bladder; while others, with every appearance of being right, recommend the cutting gorget to be with- drawn immediately it has completed the wound ; for then the bladder contracts, and its fundus is liable to be cut. The gorget should be withdrawn in the same line in which it entered, pressing it towards the right side, in order to prevent its making a second wound. If, however, the operator should prefer passing the forceps into the bladder, along the gorget, the latter instru- ment must be kepf quite motionless, lest its sharp edge do mischief; and, at all events, as soon as the forceps is in the bladder, the cutting gorget is to be withdrawn. Some operators withdraw the cutting gor- get, and introduce a blunt one for the gui- dance of the forceps ; a step certainly un- necessary, as the latter instrument will ea- sily pass, when the incision into the bladder is ample and direct, as it ought always to be. The operator has next to grasp the stone with the blades of the forceps ; for which purpose, he is not to expand the instrument as soon as it has arrived in the bladder ; but he should first make use of the instrument as' a kind of probe, for ascertaining the exact situation of the stone. If this body should be lodged at the lower part of the bladder, just behind its neck, the operator is to open the forceps immediately over the stone, and after depressing the blades a little, is gently to shut them, so as to grasp it. Certainly it is much more scientific to use the forceps at first, merely for ascertaining the position of the stone : for when this is known, the surgeon is much more able to grasp the ex- traneous body in a skilful maimer, than if he were to open the blades of the instru- ment immediately, without knowing where they ought next to be placed, or when shut. No man of experience can doubt that the injury, which the bladder frequent- ly suffers from rough, reiterated, awkward movements of the forceps, is not an unconr mon cause of such inflammation of this' viscus, as too often extends to the perito- naeum, and occasions death If the surgeon cannot readily take hold of the stone with the forceps, he should in- troduce his fore and middle fingers into the rectum, and raise up the extraneous body, when it may generally be easily grasped. The stone should be held with sufficient LITHOTOMY. '2d l instance, however, the surgeon should gently examine the cavity of the bladder with his fore-finger ; for, it would be an inexcusable neglect to put the patient to bed with ano- ther stone in his bladder. After the operation, a simple pledget should be laid on the wound, supported by a T bandage ; the patient should lie in bed on his back, with his thighs closed ; a piece of oil cloth, and some folded napkins should be laid under him for the reception of the urine, and, if there be much pain, a large opiate should be administered ; but, as the latter medicine is a stimulant, if it can be dispensed with, so much the better. An occasional embarrassment to lithoto- iirmness to keep it from slipping away trom the blades, but not so forcibly as to incur the risk of its breaking. Sometimes the extraction of the stone is attended with difficulty, owing to the ope- rator having chanced to grasp it in a trans- verse position, in which circumstance, it is better to try to change its direction, or let it go altogether, and take hold of it in ano- ther manner. When the stone is so large, that it cannot be extracted from the wound without violence and laceration, the surgeon may either break the stone by means of a strong pair of forceps, with teeth construct- ed for the purpose ; or he may enlarge the ■wound with a probe-pointed crooked bis- toury, introduced under the guidance of the mists is the circumstance of stones in the tore-finger of the left hand. The latter plan bladder not being always free and detached • is generally the best of the two ; for, break- some are embraced verv tightly bv the coats ing the stone is an exceedingly unpleasant of this viscus ; others are partially en^ed circumstance, as it creates serious danger of in the ureters : they are sometimes fixed” in calculous fragments remaining behind. the neck of the bladder; and are not uii- However, as nothing can justify the exer- frequently found lodged in saccuii accident- tion of force m pulling out a stone, if the ally formed. These cysts are of different operator should be afraid of making the sizes: some are small, and exist in a consi- wo.un.d ra ^ re am ple, ('/■ I2/7J0.) LITHOTOMY'. 203 OF SOME PARTICULAR METHODS AND IN- STRUMENTS. M. Foubert, a very eminent surgeon at Paris, devised and practised a plan of his own, which, however, has not been consi- dered by others as worthy of being imitated. The patient having retained his urine, so as to distend his bladder, an assistant, with a convenient bolster, presses the abdomen a little below tbe navel in such a manner, that, by pushing the bladder forwards, he inay make that part of it protuberant which lies between the neck and the ureter. The operator, at the same time, introduces the fore-finger of his left hand up the rectum, and drawing it down towards the right but- tock, pushes in a trocar on the left side of the perinasum, near the great tuberosity of the ischium, and about an inch above the anus. Then the trocar is to be carried on parallel to the rectum, exactly between the erector penis and accelerator urinae muscles, so as to enter the bladder on one side of its neck. As soon as the bladder is wounded, the operator withdraws his fore-finger from the anus. In the upper part of the cannula of the trocar, there is a groove, the use of which is to allow some urine to escape, immediately the instrument enters the bladder, so that the trocar may not be pushed in any fur- ther ; but its principal use is for guiding the incision. As soon as the urine began to flow, Foubert, retracting the trocar a little, without drawing it quite out of the cannula, introduced the point of a slender knife into the groove in the cannula ; and by the gui- dance of this groove he ran it onwards into the bladder, and was aware of the knife having actually entered this viscus, by the urine flowing still more freely. Then rai- sing the knife from the groove, he made his incision about an inch and a half in length, through the neck of the bladder, by moving the knife from that point at which it had entered upwards towards the pubes. And finally, by moving the handle more largely than the point of the knife, he opened the outer part of the w ound to whatever extent the size of the stone seemed to require, and then, withdrawing the knife, he introduced a blunt gorget to guide the forceps. An effort was made by Thomas to im- prove thi3 method ; but he failed, and it was never much adopted. The inability of many bladders to bear being distended, is an insuperable objection ; for, without this, the trocar is liable to pass between the. blad- der and rectum, and even through the blad- der into the pelvis. ( Memoires de l’ Acad. de Chir. 663, Vol. 1. Le Dran’s Parallllt. Sharp's Critical Inquiry. J. Bell's Princi- ples, Vol. 2.) In the year 174S, Frere Come’s method of performing the lateral operation began to attract considerable notice. The operation was done with a particular instrument, call- ed the lithotome cache , by means of which the prostate gland and neck of the bladder were divided, from within outwards# The lithotome cach6 is entitled to much atten- tion, because it is still generally used in several parts of the continent, and some- times in this country, especially by the sur- geons of the Westminster Hospital. “ In France (says M. Roux) if there is any mode of operating more common than others, and preferred by the majority of practitioners, it is that in which the instru- ment, named the lithotome cache , is employ- ed.” (See Parall&le de la Chirurgie Ang- loise , tyc. P- 3 IS. Frere Come does not ascribe the invention of this instrument to himself ; but acknowledges that it resembles ihe knife for operating upon hernia, said to have been devised by a French surgeon-of the name of Bienaise. It consists of a han- dle and the blade part. The latter is slightly curved, about as thick as a quill, furnished with a beak, and excavated so as to form a sheath for a knife of its own length. By means of a kind of lever, the knife can be made to pass out of the sheath, and the distance to which the blade projects also admits of being regulated with precision. For this purpose, the handle is divided into six sides, numbered 6, 7, 9, 11, 13, and 15, and which, according as they are more or less elevated, allow the lever to be depress- ed in different degrees, and the knife to move out of its sheath in the same propor- tion. Thus the surgeon can at his option make an incision through the prostate gland and neck of the bladder ot six different lengths. When the lithotome cache is to be used, the patient must be placed in the same pos- ture as in every other mode of practising the lateral operation ; and after a staff has been introduced, an oblique incision is to be made from the raphe of the perinajum, to a point situated rather more towards the anus, than the innermost part of the tuberosity of the ischium. The bulb of the urethra should not be cut, and not too much of the mem- branous part of the urethra The fat and transverse muscles having been divided, arid the urethra opened, exactly as in tbe com- mon operation, the scalpel is to be put down, and the beak of the lithotome introduced into the groove of the staff. Of course, the surgeon, previously to the operation, will have settled the distance, to which the blade of the instrument is to pass out of the sheath, and which must necessarily depend upon the age of the subject, and the presumed size of the calculus. When the beak of the lithotome has been inserted in the groove of the staff, the surgeon is to take hold of the handle of the latter instrument with his left hand, and bring it a little towards himself, at the same time pushing the lithotome into the bladder, with the handle depressed as much as possible. The staff is now to be withdrawn, and the surgeon is to try to feel the stone with the sheath of the other in- strument, in order to be able to judge of the size of the calculus, and whether the dis- tance, to which the blade of the knifs is in- tended to move out of the sheath, is such as Tc likely to make an opening of due. but net. 2.0/t LITHOTOMY unnecessary magnitude. Things being pro perly determined, the lithotorne is to be held in a position calculated to make a division of the parts which is parallel to the cut in the integuments, and, by means of the lever, the cutting blade of the instrument is then to be disengaged from its sheath. The surgeon is next to draw the opened lithotorne towards himself, in a perfectly horizontal manner, so as to make the requisite division of the pros- tate gland and orifice of the bladder. As Sabatier observes, Frere Come’s me- thod undoubtedly possesses all the advanta- ges of the lateral operation, besides being more easy than Cheselden’s plan, and most of the other modes, subsequently proposed, for cutting the neck of the bladder with per- fect smoothness, and to a sufficient extent to allow the calculus to be removed, without any laceration of the parts. ( Mtdecine Ope- ratoirc, T. 3, p. 199.) There have been several objections urged against the use of the lithotorne cache. 1. ft is said that the size of the incision is not? always proportioned to the distance, to which the knife moves out of the sheath, and that the instrument, when opened to No. 13 or 15, sometimes makes a smaller in- cision, than when opened only to No. 5 or f 7. This uncertainty is said to depend upon the greater or less contraction of the bladder in different subjects. For my own part, I confess, that I am not inclined to put much credit in the accuracy of this last explanation, and suspect the dif- ference sometimes observed must depend upon the operator not taking care to draw out the instrument in a horizontal direction, a thing which is always easy to be done. 2. Frere Come himself made his incision too high, so that an extravasation of urine in the scrotum followed some of his opera- tions ; but the above method of operating is free from any objection of this kind. 3. Some surgical writers have exaggera ted the danger of cutting the body of the bladder too extensively with the lithotorne, and thus producing internal hemorrhage. However, this cannot happen, unless the surgeon raise the handle of the instrument improperly at the moment of withdrawing it, and as Sabatier himself allows, it is rather the fault of the operator than of the opera- tic n. 4. The arteria pudica profunda and the rectum, which some authors conceive to be endangered, must always he in absolute safety, if the edge of the knife of the litho- tome be turned in the direction above re- commended. I think that for a surgeon, who under- stands the right principles of lithotomy, this is one of the best ways of performing the operation. When I was at Paris in 1815, I saw Dr. Souberbielle operate very skilfully with the lithotorne cache. A stone of considerable size was extracted from a, gentleman, who was, I should think, not less than 70. No apprehensions were entertained of ill suc- cess, as I understood that this operator hard- ly ever lost a patient. M. Roux, when he visited England, seems not to have been informed, that at the West- minster Hospital, the lithotorne cache has been commonly employed for many years past. It has also been sometimes used at Guy’s Hospital by Sir A. Cooper. When M. Roux likewise finds fault with the bad construction of this instrument, as made in London, I suspect, that he cannot have seen those which are made and sold by Mr. Evans. (See Voyage fait a Londres, ou Pa- ralltle de la Chirurgie Angloist , fyc. p . 318.) Le Cat, a surgeou of Rouen, in Norman- dy, devised a mode of lithotomy which would be too absurd to be described, were it less renowned. He thought the neck of the bladder might be dilated, like the wound, and his operation was deformed with all the cruelty of the Marian method, and every er- ror attendant on the infant state of the late- ral operation. He first introduced a long wide staff; he cut forward with a common scalpel, through the skin and fat, till he could distinguish the bulb, the naked urethra, and the prostate gland. Secondly, with another knife, the urethrotome, having a groove on one side, he opened the urethra, just before the prostate, and fixing the urethrotome in the groove of the staff, and holding it steady, rose from the kneeling posture, in which he performed the outward incision. Thirdly, holdingthe urethrotome in the left hand, he passed another knife, the cystotome, along the groove of the urethrotome, and the beak of the cystotome being lodged in the groove of the urethrotome, it was pushed forwards, through the substance of the prostate gland into the bladder. Fourthly, drawing the cystotome a little backwards, he gave the staff to an assistant to be held steadily, and lifting a blunt, gorget in the fight hand, he placed the beak of it in the groove of the cystotome, and pushed it onwards, till it glided from the groove of the cystotome., along the groove of the staff into the bladder. Then, true to the principles of the apparatus major, and never forgetting his own pecu- liar theory, little incision, and much, dilate lion, he forced his fingers along the gorget, dilated the neck of the bladder, and so made way for the forceps. (J. Bell's Principles , Vol. 2 ) In 1741, Le Dran described an operation, the introduction of which has been claimed by several since his time. A staff being in- troduced, and two assistants keeping open the patient’s knees, while a third stands on one side of him on a chair, (Le Dran says,) “ l then raise up the scrotum, and directing the last assistant to support it with both hands, so as to avoid bruising it, by pressing it either against the staff, or the os pubis, I place his two fore-fingers on each side of the part, where the incision is to be made ;, one of the fingers being laid exactly along that branch of the ischium, which rises to- wards the pubes, and the other pressed upon the raphe, that the skin may be kept fixed and tight. While 1 thus place the fingers of LITHOTOMY. 205 the assistant, who supports the scrotum, I still keep hold of the handle of the staff, and direct it so as to form a right angle with the patient’s body ; at the same time taking care that the end of it is in the bladder. This position is the more essential, as all the other instruments are to be conducted along the groove of this. If the handle of the staff were kept, inclined towards the belly, the end of it would come out of the bladder, and the gorget, missing its guide, would slip between that and the rectum. “ The staff being rightly placed, I take the knife from the assistant, who holds the instruments, and put it into my mouth ; then pressing the beak of the staff against the rectum, I feel the curvature of it through the perinaeum. The incision ought to ter- minate an inch and a hall below where we feel the bottom of the curvature. If we do not carry this incision sufficiently low, it may happen not to be of a size to allow the ex- traction of a large stone, and might lay us under the necessity of extending it further afterward, for the skin will not lacerate here, nor easily give way for the passage of the stone. 1 therefore begin the incision from the lower part of the os pubis, continuing it down to the place that I before directed for its termination ; after which I pass the point of the knife into the groove of the staff, and cutting from below- upwards, without taking the point out of the groove, I open the an- terior part of the urethra as far as the inci- sion that is in the skin. “ The Leak of the staff, which w T as press- ed upon the rectum, must now be raised and pressed against the os pubis. At the same time, I turn the handle towards the right groin, that the groove, which is at the beak of the staff, may face the space be- tween the anus and the tuberculum isehii on the left sid.e. Then carrying the point of the knife down the groove, I slide it along the beak, turning the edge, that it may face the space between the anus and tuberosity of the ischium. By this incision, I exactly divide the bulb of the urethra, and by doing this on its side, we are sure to avoid wound- ing the rectum, w hich for want of this pre- caution has been often cut. This first inci- sion being made, I again pass the point of the knife into the curvature of the staff to the part where it bears against the peri- nseum, and direct it to be held there by the assistant who supports the scrotum. This done, I take a large director, the end of which is made with a beak, like that of a gorget, and conveying this beak upon the blade of the knife, into the groove of the staff. I draw 1 the knife out. 1 then slide the beak of this director, along the groove of the staff, into the bladder, and I withdraw the staff, by turning the handle towards the pa- tient’s belly. The following circumstances will sufficiently satisfy us, that the director is introduced into the bladder; first, if itstrikes against, the end of the staff, which is closed ; secondly, if the urine runs along the groove. I next feel for the stone with this director, and having found it, endeavour to distin- guish its size and surface, in order to make choice of a proper pair of forceps ; that is, one of a stronger or weaker make, or of a large or small size, agreeably to that of the stone ; after which I turn the groove towards the space, between the anus and tuberosity of the ischium, and resting it there, convey a bistoury along the groove, the blade of which is half an inch broad, and about three quarters of an inch long. I continue the in- cision made by the knife in the urethra, and entirely divide the prostate gland laterally, as also the orifice of the bladder; and, I am very certain, that the introducing the use of these two instruments, which are not em- ployed by other lithotomists, does not pro- long the operation a quarter of a minute, but rather shortens the time, both by facili- tating the dilatation, that is afterward to be made with the finger, and by rendering the extraction of the stone more easy. The bis- toury being withdrawn, the groove of the director serves to guide the gorget into the bladder. I then introduce my fore-finger along the gorget, (which is now easily done, as the urethra and prostate, being divided, do not oppose its entrance) and with it I di- late the passage for the stone, in proportion to the size, of w'bich I discover it to be This dilatation being made, I withdraw my finger, and use the proper forceps.” (Le Dran's Operations, Edit. 5, 1784, London .) Professor Pajola, of Venice, was the pupil of Le Cat, and his method resembles that of his master He is stated to have cut for the stone 650 patients with success ; which de- serves notice, because his operation has for its principles, dilatation, and no division of any part of the bladder. He makes an inci- sion into the groove of the staff, with a lan- cet-pointed, double-edged knife, called an urethrotome, the blade of which has upon its centre a groove, that is continued to its very point, and serves to guide the beak of ano- ther instrument, called the eystotome, into the groove of the staff. As the professed in- tention of the eystotome is only to cut the prostate gland, its name is ridiculous. It consists of a handle, and very slender blade, which is not connected with the handle, but with its sheath, by means of a little joint, close to the beak of the instrument. When the eystotome is opened as far as possible, the end of the blade furthest from the beak, is twelve lines from the sheath. In this po- sition, it is held by a transverse piece of steel, which admits of being pushed more or less out at the option of the surgeon, and can be fixed by means of a screw. Pajola, like Scarpa, considers cutting the neck of the bladder dangerous, and he merely divides the prostate, after which he introduces a blunt gorget, and along this a species of forceps for dilating the neck of the bladder in all direc- tions. (X. F. Rudtorffer uber die Operation des Blasensleins nach Pajola' s Methode.) As Langenbeck observes, great as the success of this lithotomist has been, his method of ope- rating has little to recommend it ; and every- thing must be ascribed to his individual skill, and intimate knowledge of the parts. Lan- LITHOTOMY. 206 genbeck even prefers Le Cat’s method, in which there is no need of such a multiplicity of instruments. The blunt gorget and dila- tor are perfectly unnecessary, as the finger would do the purpose of both. In the former editions of this Dictionary, I have not taken any notice of what has been termed by the French, “ Operation a deux temps," and which was first mentioned by Franco. If, by this plan, it be intended, that the incision should be made at one period, and the extraction of the stone not attempted till u subsequent period, I cannot too strongly re- probate the practice. But, if I am to under- stand, that the postponement of the comple- tion of the operation is only to be adopted, as a matter of necessity, when the patient cannot bear the longer continuance of the unsuccessful efforts to extract the stone, of course, I can only say, that every endeavour should be used to avoid this very disagreeable dilemma, by making in the first instance an adequate opening, and (if this cannot be done) by breaking the calculus, and carefully remo- ving all the fragments. Some further consi- derations against delaying the completion of the operation will be found in the 2d vol. of the First Lines of Surgery. The danger of the beak of the gorget slip- ping out of the groove of the staff, is one of the chief objections urged agtiinst the em- ployment ot the first of these instruments, in order to obviate this inconvenience, Sir Charles Blicke bud the groove of the staff, and the beak of the gorget, so constructed that they locked into each other, and conti- nued fixed till near the extremity of ttie staff. The contrivance, though plausible and inge- nious, is not much used : the point of con- tact of the beak and body of the instrument is necessarily so small, that it is liable to break. It is allowed, however, that this objection might be removed ; but another one is still urged, viz. the beak and groove catching on each other, so as to resist the efforts made to introduce the gorget into the biuddei. Every operator knows, that much of the satety of the lateral operation, as performed at present, depends on the ease with which the beak of the gorget slides along (he groove of the staff. Le Cat, in 1747, is said to have devised a si- milar intention. Some operators have a good deal of trou- ble in dissecting into the groove of the staff. Sir James Earle invented an instrument to render this part of the operation more easy. It consists ot a short staff, with an open groove, connected by a hinge with the han- dle of another staff, ot the usual size, shape, curvature, and length, which may be called the long staff. The hinge, by means ot pm, is capable ot being disjointed at pleasure. Tbe short staff is sufficiently curved to go over the penis and scrotum, and long enough to reach to that part ot the long staff winch is just below llte beginning ot its curvature. The end of the short staff, made somewhat like a pen, with the sides sharpened and finely pointed, is adapted to shui into tbe gioove of the long staff, and its cutting edges are de- fended from being injured by a proper recep- tacle which is prepared for it in the groove of the long staff. When the instrument is shut, the groove of the short staff leads into that of the long one, so as to form one con- nect and continued groove. The short staff' is rendered steady by the segment of an arch projecting from the long one through it. The long staff, separated from the short one, is first introduced in the usual rnanuer, and, the stone having been felt, the short staff' is to be put on tbe other at the hinge. Tbe incision is then to be made in the usual man- ner, through the skin mid cellular membrane, and a second incision through the muscles, so as nearly to lay bare the urethra. The operator then being perfectly convinced that (lie extremiiy of (he long staff is sufficiently within the bladder, must bring the end of the short staff down, and press it against the urethra, which it will readily pierce, and pass into the cavity prepared for it in the groove of the long staff. The two pieces being now firmly held together by the operator’s left hand, nothing remains to be done, except applying the beak of the gorget to the groove of the short staff*, and pushing it on till it is received in the groove of the long one ; and if this latter be made with a contracted groove, it will just enter where the contrac- tion begins, and thus must be saiely conduct- ed into the bladder. ( Earle on the Stone ; Appendix; Edit. 2, 1796.) Deschamps des- cribes an instrument, invented by Jardaa, surgeon of Montpelier, which bears a resem- blance to Earle’s double staff, but was more complicated, being designed to support the scrotum, and also press the rectum out of the way. The late Mr. Dease, of Dublin, and Mr. Muir, of Glasgow, considering that the gor- get was more apt to slip from the staff’ in con- sequence of the latter being curved, and that its beak never slips from tbe groove of the staff in operating on women, proposed, like Le Dran, to convert the male into the temale urethra. They introduce, as usual, a curved grooved staff' into the bladder, make the common incisions, and open the membra- nous part of the urethra ; but -instead of in- troducing a gorget on the curved staff, they conduct along the groove a straight director, or staff’, into the bladder, and immediately withdraw the other. The gorget is then in- troduced. In this manner the operation may be very well performed with a narrow bis- toury, as was advised by Mr. A. Burns. LITHOTOMY, AS PERFORMED WITH A KNIFE, INSTEAD OF A CUTTING GORGET, LY SE- VERAL OF THE MODERNS. We have alreidy described, bow Fr^re Jacques and Chesclden, used to operate with a knife, without any cutting gorget, in the early state of the lateral operation. The success which attended Uie excellent prac- tice of ihe latter surgeon, certainly far ex- ceeds what attends the present employment of the gorget, for, out of 52 patients whom he cut successively for the stone, he only lost two; and out’of 213, of all age?, cm,- LITHOTOMY. 207 stitutions, (co . only 20. These facts are strongly in favour of abandoning the use of the gorget, and doing its office with a knife. The objections to the gorget are nume- rous and well founded. In the hands of many skilful operators, its beak has slipped out of the groove of the staff, and the in- strument has been driven either betvveen the rectum and the bladder, or into the intestine instead of the latter viscus. Sir James Earle remarks : (l I have more than once known a gorget, though passed in the right direction, pushed on so far, and with such violence, as to go through the opposite side of the blad- der.” Bromfield, even when operating with a blunt gorget, perforated the bladder and peritonaeum, so that the abdominal viscera came out of the wound. (P.1270.) I now know of at least three instances, in which the gor- get, slipping from the staff, completely sever- ed the urethra from the bladder ; the stone was not taken out ; and the patients died. We will suppose, however, that the pre- ceding dangers of the gorget are surmounted, as they certainly may be, by particular dex- terity, seconded by the confidence of expe- rience. The gorget is introduced, but what- ever kind of one has been used, the wound is never sufficiently large for the easy pass- age of any stone, except such as are below the ordinary size. Camper has noticed this fact : “ Hawkensius solo conductore, cujus margo dexter in aciem assurgit, idem praes- tat : omnts plagam dilatant, ut calculum ex - trahant : dilacerentur igitur semper vesicce ostium et prostata .” (P. J 14.) Dease says : ct In ail the trials that I have made with the gorget on the dead subject, l have never found the opening into the biadder sufficient- ly lar^e for the extraction of a stone of a middling size, without a considerable lacera- tion of the parts. I have frequently taken the largest-sized gorget, and could not find, in the adult subject, I ever entirely divided the prostate gland, if it was any way large ; and in the operations that were performed here on the living subject, if the stone was large, the extraction was painfully tedious, and effected with great difficulty ,**• and, in some cases, not at all.” I shall dismiss this part of the subject with referring the reader to the spirited and cor- rect remarks on the objections to the gorget in Mr. John Bell’s Principles, Vol. 2. Part 2. The latterauthor recommends the external incision, in a large man, to commence about an inch behind the scrotum, and to be car- ried downwards three inches and a half, midway between the anus and tuberosity of the ischium. The fingers of the left hand, which at first kept the skin tense, are now applied to other purposes. The fore-finger now guides the knife, and the operator pro- ceeds to dissect through fat and cellular substance, and muscular and ligamentous fibres, till the wound is free and open, till all sense of stricture is gone ; for it is only by feeling opposition and stricture that we re- cognize the transverse muscle. When this hollow is fairly laid open, the external inci- sion, which relates merely to the free extrac- tion of the stone, is completed. If it were the surgeon’s design to operate only with the knife, he would now push his fingers deeply into the wound, and, by the help of the fore- finger, dissect from the urethra along the body of the gland, till he distinguished its thickness and solidity, and reached its back part. Then, plunging his knife through the posterior portion of the gland, and settling it in the groove of the staff, he would draw it firmly and steadily towards him, at the same time pressing it into the groove of this instru- ment, and then the free discharge of the urine, assuring him that the prostate and neck of the bladder were divided, he would lay aside his knife, pass the left fore-finger into the bladder, withdraw the staff, and intro- duce the forceps. ( John Bell , p. 197.) Mr. Charles Bell describes the following method of operating with a knife, instead of a gorget. A staff grooved on the right side, a scalpel with a straight back, and the common lithotomy forceps, are the indis- pensable instruments. The staff is kept in the centre, and well home into the bladder. The surgeon making his incision under the arch of the pubes, and by the side of the anus, carries it deeper towards the face of the prostate gland ; cutting near to the stall', but yet not cutting into it, and avoiding the rectum by pressing it down with the finger. Now carrying the knife along the staff, the prostate gland is felt. The point of the knife is run somewhat obliquely into the urethra, and into the lateral groove of the staff^just before the prostate gland. It is run on, until the urine flows. The fore-finger follows the knife, and it is slipped along the back of it, until it is in the bladder. Having carried the fore-finger into the bladder, it is kept there, and the knife is withdrawn. Then the forceps, directed by the finger, are introduced. (C. Bells Operative Surgery, Vol. 1, p. 361.) Mr. Allan Burns, of Glasgow, recommends the following method : “ The plan (says he) introduced by Cheselden, and revived by Mr. J. Bell, I would assume, as the basis of the operation ; but still, along with their mode, I would blend that of Mr. Dease, by which, I imagine, we may overcome some of the disadvantages attendant on each con- sidered individually. u For more than twelve months, I have been in the habit of showing such an ope- ration, which is as simple in its performance, as the one in general use, is attended with less danger to the patient, permits of an in- cision varying in size, according to the wish of the operator, and completely prevents injury of the rectum, or pudic artery. To perform this operation, I introduce into the urethra a common curved staff, then make the usual incision into the perinaeum, di- vide fully and freely the levator ani, so as to expose the whole extent of the membranous part of the urethra, the complete extent of the prostate gland, and a portion of the side of the neck of the bladder. When this part of the operation is finished, I open the membranous part of the urethra, and intro- L1TH0T0MV. 2u3 duce through the slit a straight or female staff, with which l feel the stone, and then withdraw the curved staff. This done, I grasp the handle of the staff firmly in my left hand, and with the right lay hold of the knife. Having ascertained that the two in- struments are in fair contact, l rest the one hand upon the other, pressing them together, and then by a steady extraction, I pull out the knife and staff together, which is prefer- able to drawing the knife along the staff ; it prevents the risk of the one slipping from the other ; it guards the bulb of the urethra, and every other part from injury ; for, be- tween them and the cutting instrument, the staff is interposed &c. “ When introdu- cing the knife, the side of the blade must belaid flat along the fore-finger of the right- hand which is to project a little beyond the point. In this state the finger and knife are to enter the wound, opposite the tuber ischii ; but, in proportion as they pass along, they are to be inclined forward, till at last, with the point of the finger, the staff is to be felt through the coats of the bladder, a little beyond the prostate, and rather higher than (he orifice of the urethra. Here the knife is to be pushed, with the finger, through the bladder, and when the point is fairly fixed in the groove of the staff, the operation is he judges the incision in the fneck of the bladder to be too small for the easy extrac- tion of the stone, he next introduces into the bladder a straight probe-pointed bistoury, with its side close to the forepart of his finger, and its cutting edge upwards. By turning this edge towards the left side, and by keeping the point of his finger always beyond the point of the bistoury, he may safely divide, in the direction of the first in- cision, as much of the prostate gland, and neck of the bladder, as he shall deem neces- sary.” (See Observations on Lithotomy , <^c. with a Proposal for a new Manner of Cutting for the Slone, by J. Thomson , M. D. one of the Surgeons of the Royal Infirmary , $-c. Edinb . 1808.) In this small work, the reader will find additional particulars. Mr. Allan, who is a strenuous advocate for using the knife instead of the gorget, directs us, after laying bare the urethra, and bring- ing the staff so as to form a right angle with the patient’s body, to feel that the instru- ment is fairly lodged in the bladder. The operator is to use the fore-finger of his left- hand as a director in feeling for the groove in the staff, and in distinguishing the pros- tate eland ; and, with this finger, he is to de- press the rectum, and direct the deeper part of his dissection. “ Feeling the gland, with to be finished by the steady extraction of the point of the fore-finger of the left-hand, both instruments.” (Man Burns , in Edin- burgh Surgical Journal , No. 13.) The knife of Cheselden does not require so much violence to divide the parts as the gorget does ; cannot slip in some instances before, in others behind the bladder ; and it will make a wound sufficiently ample for the easy extraction of the stone, without the least laceration. The possibility of its wound- ing the rectum, Dr. Thomson thinks might be obviated by employing it as follows “ After having made the external incisions, and divided the membranous part of the urethra, in the way that it is usually done for the introduction of the beak of the gorget, a straight-grooved staff is to be introduced into the groove of the curved staff, and pushed along it into the bladder. The curved staff is then to be withdraw n, and the surgeon, and the groove of the staff in the upper part of the wound, the assistant is desired to steady his hand, and the operator, holding his knife as he does a writing pen, his fin- gers an inch and a half from the point, turns up its edge towards the staff, and strikes its point through the membranous part of the urethra into its groove, half an inch before the prostate gland. He now turns the back of the knife to the staff, slides it a little back- wards and forwards in the groove, that he may be sure he has fairly entered ; then shifts the fore-finger, with which he guidesthe incision, places it under the knife, and carries always before the point of it, to prevent the rectum being wounded ; he then lateralizes the knife, enters the substance of the prostate, is con- scious ©f running the scalpel ihrough its solid and fleshy substance, and judges, by the laying hold of the handle of the straight staff finger, of the extent of the incision which he with his left hand, and turning the groove now makes. The urine flow's out ; he slips upwards and a little outwards, presses the his finger into the opening, withdraws the back of it downwards towards the right scalpel, and gives it to an assistant, who tuber ischii, and holds it steadily in that o- hands him the forceps, which he passes into sition. The point of a straight-backed seal- the bladder, using the fore-finger of his left- pel being now introduced into the groove of hand, which is still within the wound, as a the staff, with its cutting edge inclined up- conductor. The forceps instantly encoun- wards and a little outwards, is to be pushed ter the staff, w hich serves to conduct them gently forwards into the bladder. The size of the scalpel need only be such as will make a wound in the prostate gland and neck of the bladder, sufficiently large to admit the fore-finger of the left-hand. The scalpel being removed, this finger is lo be introduced into the bladder, through the wound which has been made, and the staff may then be withdrawn. With the finger the surgeon endeavours to ascertain the size and situa- tion of the stone. If. after this examination, safely into the bladder, while the finger guides them through the wound ; &c.” (Allan on Lithotomy, p. 48, Edinb. 1808.) 1 leave the reader to judge, which of the foregoing modesof operating with a common knife claims the preference. Perhaps Chesel- den’s manner, which is also Mr. John Bell’s, is as deserving of recommendation as any. The methods of operating with a knife, as practised by Klein and Langenbcck, I shall not here repeat, as they were described in tlw LITHOTOMY 209 last edition of the First Lines of Surgery, ac- companied with many valuable practical observations made by these judicious and skilful surgeons. That the performance of lithotomy with a knife, when the operator has ihe assistance of a proper staff, cannot be difficult, may be inferred from there being no particular difficulty in the method, even when no staff at all is employed. In the spring of the year 1814, when at Oudenbosch in Holland, I was requested by Sergeant Ryan, of the 1st Foreign Veteran Battalion, to see his little boy, about four years old, who was troubled with symptoms, which made me immediately suspect, that there was a stone in the bladder. As I had no sound, I in- troduced into this viscus a small silver cathe- ter, which distinctly struck against a cal cuius. Without taking the instrument out again, I determined to perform lithotomy with a common scalpel. Indeed, no other mode could be adopted, as we had neither staff, gorget, nor lithotomy instruments of any kind. After making the external part of the incision in the common way, I found that the catheter afforded me no guidance. I therefore withdrew it, and dissected deeply by the side of the prostate gland, till the fore-finger of my left hand passed rather be- yond it. The scalpel was then plunged into the bladder, behind this gland, under the guidance of my left fore-finger, and with the edge turned towards the urethra. The ne- cessary division of the prostate and neck of the bladder was then made by cutting in- wards and upwards in the direction of the rest of the wound. With a small pair of ordinary dressing forceps, a calculus, rather larger than the end of the thumb, was easily extracted. This operation was done at the Military Hospital, in the presence of Dr. Shanks of the 56th regiment, and several other medical officers. Not a single bad symptom ensued, although the army unex- pectedly moved into the field three days afterward and the child travelled about for some time in a baggage cart, in an exposed and neglected state. The wound was conse- quently rather longer in healing than usual ; but, this was the only ill effect. The little boy in the end completely recovered. Of late years, many surgeons have chosen to perform lithotomy with several kinds of beaked scalpels. The practice, indeed, is still gaining ground. Mr. Thomas Blizard’s knife is one of the best. Its blade is long, straight, and narrow, and, like the gorget, is furnished with a beak, by means of which it admits of being conducted along the groove of the staff into the bladder, after the ex- . ternal incisions have been made. The staff is then withdrawn, and the operator has now the power of making the incision through the prostate and neck of the bladder down- wards and outwards to any extent, which the parts w'ill allow, or the case require. This is one of the principal advantages which beaked long narrrow knives have over gorgets, which, after their introduction, can- not be further used for the enlargement of the Vojl If 27 wound. The narrow knife will also cut more safely dow awards and outwards than any gor- get ; nor is it subject to the serious danger of slipping away from the staff, and going we know not where ; because the moment its beak and extremity have entered the bladder, the staff is no longer necessary, as the proper extent of the blade will then readily pass in without the aid of any conductor at all. I need hardly observe, also, that, in this method, we have nothing like the perilous and violent thrust of the gorget, which, in the event of a lMle unsteadiness in the ope- rator’s hand, or of any fault either in the position of the staff, or the direction of the gorget, will do irremediable and fatal mis- chief. A FEW GENERAL REMARKS ON THE BEST MODE OF MAKING THE INCISION IN, THE LATERAL OPERATION : AND SOME REFLEC- TIONS ON THE PRINCIPLES INCULCATED BV PROFESSOR SCARPA. Perhaps of all the great operations in sur- gery, lithotomy is that, in which great awk- wardness, mortifying failures, and dangerous blunders, are most frequently observed. Many a surgeon, who contrives to cut off limbs, extirpate large tumours, and even tie aneurismal arteries, w'ith eclat , cannot get through the business of taking a stone out of the bladder in a decent, much less, a masterly style. This fact is so familiarly known in the profession, and its truth so ofteii exemplified, that I may well be excused the unpleasant task of relating in proof of it all the disasters, which have come to my own personal knowledge. But. I must take the liberty of remarking, that, in this branch of surgery, a great number of individuals d» not profit by these instructive lessons of ex- perience. The more they see of lithotomy, the more they are convinced of its dangers ; yet, too often, instead of studying the causes of ill success, they merely derive from the examples before them, a suspicion of the un- skilfulness of the operator, or some dis- couraging conjectures about the difficulties of the operation. The establishment of certain prineiplesto be observed in lithotomy, appears the most probable way of diminishing the frequency of the accidents and failures of this common operation. If these principles are not viola- ted, it is of less consequence what instru- ment is employed, for the surgeon may do nearly the same thing with an ordinary dis- secting knife, a concealed bistoury, a beaked Scalpel, or a well-made gorget. After the very opposite principles, and different methods of cutting for the stone, which are explained in the preceding columns, as preferred by different surgeons, I think it maybe useful to offer a few gene- ral observations on the proper direction and size of the incision. These points, which are of the highest practical consequence, in regulating the principles, w hich ought to be observed in lithotomy, are far from being Settled, as must be plain to every body wbo LITHOTOMY. 210 recollects that Desault, Mr. John Bell, Klein, and Langdenbeek, have recommended a free opening ; Scarpa, Callisen, and others, a small one ; that Mr. Ahernetby and Scarpa employ gorgets, which cut upwards and outwards, at angles of 45° and 69° from the axis of the urethra ; and t hat the gorgets of of Cruickshank, B. Beil, Desault, Mr. Cline, and most other surgeons arp constructed for cutting either directly outwards, or outwards and inwards. It appears to tne, that the incision, through the whole of the parts cut in lithotomy, should always be made in a straight, regular, direct manner, from the surface of the skin in the perinasurn to the termination of the wound in the urethra and bladder. In an adult subject, trie external wound should commence about an inch above Ihe anus. The impropriety of beginning it higher up has been duly insisted upon bv Sharp, Ber- trandi, Callisen, and every g.fod writer on the operation. “ II ne faut couper I’uretre que le nioins, qu’on peut, parcequ’on obtient par ce moyen one meilleure voie pour pene- trer dans la vessie sous Tangle du pubis. C'est avec raison que Sharp dit que I’incision de 1’uretre faite au dessus de cet angle est si peu utile pour l’extraclion de la pierre, qu’on n’en retireroit pas plus d’avantage en le r ou- pant presque dans toute sa longueur.” ( Ber - trandi, TraiUdes Operations, p. 127.) And Callisen lays it down as a maxim : “ Ut pffl partes baud sectione attingan'ur, quae pro calculi egressu nihil faciunt ; adeoque bulbus urethrae, et hujus pars norpore spongioso cir- cumdata intacta relinquatur.” (Sy sterna Chi- rurgice Ilodiernce ; Pars Posterior ; p.655.) Extraordinary as it may seem, it i3 not the less true, that cutting too much of t ie ure- thra is one of the most common faults still committed by modern surgeons. The inci- sion in the integuments is to be large, that is to say, at least, three inches in length in an adult subject, because a free opening in the skin is not only exempt from danger, but at- tended with many advantages, especially those of facilitating the other steps of the operation, and preventing any future lodg- ment and effusion of urine. The external wound ought to be directed towards a point situated a very little towards the anus, from the innermost part of the tuberosity of the ischium. From the line, thus made, the in- cision should he carried inward and upward, through all the parts between it and the side of the prostate gland. Another line, extend- ing from the inferior angle of the wound to the termination of the cut in the bladder, forms the precise limits, to which the depth of the incisions should reach, and no further. The great principle of making the axis of the wound as straight and direct as possible, should always be kept in view, whether the surgeon employ a common scalpel, which cuts into the bladder, from without inwards, or other instruments, which divide the pros- tate gland, and neck of the bladder, from within outwards, like the bistoire cache, beaked knives, and every kind of cutting gorget Tn the latter circumstance, the only difference consists in cutting, from the blad- der and urethra, downwards and outwards towards a point , situated a little way more in- wardly than the tuberosity of the ischium, instead of carrying the incision from this point, upwards and in wards, through the side of the prostate gland and the orifice of the bladder. The following may be enumerated as important advantages of attending to the foregoing principle : 1. The wound is made in that direction, which affords the greatest room for the ex- traction of large stones; and the axis of the incision being also as nearly straight as pos- sible, the introduction of forceps, and the passage of the calculus outward, are mate- rially facilitated. Thai these are important advantages, I think every surgeon will allow, who knows bow much the pain and danger of lithotomy depend upon the injury which the parts suffer from the force sometimes used in the extraction of the stone, and the repeated in- troduction of the forceps. Cheselden, the most successful lithotornist England ever produced, made the incision in the direction here recommended, sometimes inward and upward ; sometimes outward and downward. The following remarks of another excellent surgeon merit particular attention : — J’ai vu plusieurs fois dans les H6spitaux de Paris, que les Chirurgiens, coupant tiop en haul vers I’angle du pubis, sentoient une grand resistance au perine, quand ils vouloient re- tirer le calcul avec les lenettes ; on voyoit le p6rin6 se tum6!ier par la pression, qu’y faisoit la pierre ; en ce cas, quelques operateurs plussages abandonnoient la pierre, introduis- oient de nouveau le gorgeret, et en tournant en dessous la cannelure de celui ci, prolonged em I’incision obliquernent vers la tuberosite de l’os isohion ; et erifin a la faveur de cetle plus grande ouverture, retiroient la pierre sans causer de deonirernens.” ( Berirandi , Traiti des Operations , p. 133.) Larger stones may likewise be thus extracted, with- out being broken, than in any other mode of making the lateral incision, as must be ob- vious to every practitioner, who recollects the very limited room, afforded at the upper part of the triangular space, between the arch of the pubes, the ramus of the ischium, and the neck of the bladder. This conside- ration cannot fail to have great weight with all surgeons, who feel duly convinced, how unsatisfactory a method it is to break a cal- culus, in order to get it out of the bladder The measures necessary for the removal of all the fragments protract the completion of the operation, and seriously increase its dan- ger; while the continuance of a single part ' of the stone behind may cause a renewal of all the grievances, for the cure of which the patient submitted to the operation. By these remarks, however, I am far from meaning to say, that large calculi should nut be broken ; on the contrary, my only wish is, that the necessity for the practice may be avoided, as much as possible, by making a free inci- sion into the bladder, and even enlarging the opening, if necessary, as far ns can be done LITHOTOMY. 211 with safety, in snort, instead of breaking the stone, I prefer the practice of Mr. Marti- neau, of Norwich, perhaps the most success- ful lithotomist now living in this country, as out of 84 patients, whom he has cut, only two have died ; a statement highly favourable to operating with a knife, and making an adequate opening. “ Should the stone be large, or there be any difficulty in the ex- traction. rather than use much force, while the forceps have a firm hold of the stone (says Mr. Martineau,) I give the handles to an assistant, who is to draw them outwards and upwards, while the part forming the stricture is cut ; which is easily done, a3 the broad part of the blade becomes a director to the l^nife ; and rather than lace- rate, I have often repeated this enlargement of the inner wound two or three times.” (See Med. Ckir. Trans. Vol. 11, jj. 411.) The great advantage of the knife over the gorget, and even the necessity of employing it for adapting the size of the opening in the blad- der to the magnitude of the stone, or its fragments, are most convincingly exemplified in several cases recently put upon record. Thus Klein, with the aid of a common scalpel, extracted a calculus, which weighed twelve ounces, thirty grains ; and the patient recovered. ( Pract . Ansichten Bedeutendsten Operationen , H. 1.) In 1818, M . Mayo, of Winchester, operated with a knite, and extracted a calculus, which broke in the for- ceps, weighing fourteen ounces, two drachms, a voirdupoise, and the patient recovered. (See Med. Chir. Trans. Vol. 11, p 54, fyc.) Mr. W. B. Dickenson, of Macclesfield, aim succeeded with Mr. Gibson's knife, in taking out of the bladder a calculus, the fragments of which v\ eighed eight and a half ounces, and the patient was saved. ( Vol.cit.p . 61.) An I in the same volume may be seen other instances, in which immense calculi were removed from the bladder with various re- sults, but particularly one which weighed sixteen ounces, and which Sir A. Cooper could not succeed in breaking : he was therefore obliged to enlarge the wound, first made with the gorget >l to the sacro-sciatic ligament,” when with the aid of a hook applied to the forepart of the stone behind the pubes, and the simultaneous assistance of the forceps, he succeeded with consider- able difficulty in removing thi immense mass. The patient lived, however, only four hours after the operation. (See Med '. Ckir. Trans. Vol. 11, p. 73.) 2. The arteria pudica profunda can never be injured, because the surgeon does not let the knite, or gorget, approach nearer to the ischium, than a point which is situated a lit- tle way from the tuberosity of that bone to- wards the anus; and consequently the edge of the instrument cannot come into contact with the inside of the tuberosity and ramus of the ischium where the great pudic artery is situated. 3. The rectum will not be wounded, because the direction of the axis of the inci- sion, either downwards and outwards to the above-mentioned point, or from that point inwards and upwards, sufficiently removes the edge of the knife, or gorget, from the intestine. But, the rectum will be in still greater safety, if it be pressed down- ward with the fore-finger of the left-hand in the wound, and the prudent custom of emp- tying it, by means of a clyster, a short time before the operation, he not omitted ; for, no lithotomist should ever forget, that, when this bowel is considerably distended with feces, it rises up a little way on each side of the prostate gland. 4. As the seminal duct penetrates the lower part of the substance of the prostate gland, in order to reach the urethra, and the knife, or other instrument, employed, divides the upper portion of the side of that gland in- ward and upward, or outward and down- ward, it is obvious that the duct will not be in the least danger of. being cut. The judicious Callisen is well aware of the advantages of making a smooth, even, direct incision into the bladder ;* but, like Professor Scarpa, he is averse to making a free cut through the neck of that viscus. In- deed, as we shall presently notice, Scarpa does not sanction cutting any portion of the bladder at all. Every practitioner, who will take the trouble to look ove the history of the late- ral operation, will find, that the greater num- ber of lithotomists, who have particularly distinguished themselves by their unparallel- ed success, as Frere Jacques, Cheselden, Cosme, Mr. Martineau Dr. Souberbielle, &tc. m tde a free incision into the bladder. This fact alone is enough to r ise doubts of the goodness of the advice delivered upon this subject by Callisen and Scarpa ; espe- cially, as neither they, nor any other modern surgeon (with the exception, perhaps, of Pajola, who-e individual skill is said by Langenb'wk to make amends for the disad- vantages of his method.) can boast of having cut patients for the stones with a degree of success at all equal to that of the above-men- tioned operators. The extraordinary success which characterized Cbeselden’s practice we 1 ^ve already detailed in this volume. The accounts, which we nave, of the successful operation done by Frere Jacques and Cosme, are equally remarkable. Mr. Martineau, as I have noticed, has lost hut two patients out of 84, on whom he has operated, and this without making any se- lection, as he never rejected any one who was brought for operation. Mis patients were always kept a week in the house be- fore operating ; and this precaution, with a regulated diet, and perhaps a dose or two of opening medicine, was the only preparatory treatment. (Med. Chir. Trans. Vol. 11, p. 409.) During my stay at Paris, in 1815, I saw Dr. Souberbielle extract a stone of consider- *„Vulnus sit equate, hand angtilatum, conicae figu- vae. apice vesicam respiciente, externa pla'ga ampa > et quatuor pollicum longitudine, mideeflluxus sangui- nis, puris, loth, arena?, facilitatur. See Systema Ohi- rurp-iae Hodiernse ; Pars Posterior, p 660. fctafnias, 1800. LITHOTOMY. a 2 able size, on the plan of his well-known an- cestor. The incision was ample and direct, so that the calculus was taken out with per- fect ease. Now, as the operations of this professed lithotomist are very numerous, and lie enjoys the reputation of scarcely ever losing a patient, are we not justified in in- ferring, that the advocates for a small open- ing are promulgating the worst advice which can be offered to the practitioner? My own observations certainly tend to such a con- clusion as will be presently explained. The tract recently published by Scarpa (Memoir on the Cutting Gorget of Hawkins , tyc. trans. by Briggs ,) has for its main objects the ie- commendation of a modification of Haw- kins’s gorget, audit he inculcation ol the pro- priety of making a small limited incision in the prostate gland, without cutting any part of the bladder. As sufficient room can not thus be obtained for the extraction of even a stone of moderate size, he is an ad- vocate for the gradual dilatation of the ure- thra and orifice of the bladder. He observes, that the lateral operation, though executed with the greatest precision, does not exempt the surgeon from dilating in a certain degree the orifice of the bladder, and cervix of the urethra, the dilatation of those parts, how- ever moderate, being always necessary even where the calculus is of middling size. He states, that, in the adult, the orifice of the bladder dilates almost spontaneously to the diameter of five lines ; and he adds, that the lateral incision, within proper limits, divides the body and base of the prostate gland to the depth of four, or, at most, five lines, forming with the five, to which the orifice of the bladder naturally yields, an apertu/e of ten lines. But, says Scarpa, in an adult, a stone of ordinary size and oval figure is sixteen lines in the small diameter, to which must be added the thickness of the blades of the forceps : consequently, even after the incision has been made with the most scru- pulous exactness, the stone, though of mode- rate size, cannot pass out of the bladder, un- less the dilatation of the base of the gland and orifice of the bladder be carried to the extent of nearly eight lines, beyond the size of the aperture made with the knife. But, says Scarpa, if, in order to avoid distending the parts to the extent of eight lines, the base oi the prostate gland, together with the orifice of the bladder, and a part of its lun- dus, be divided to a depth equivalent to it, the event would necessarily be an effusion of urine into the cellular membrane, between the rectum and bladder, and consequently suppu- ration, gangrene, Jislulce, and other serious evils. (Page 4, 5.) According to Scarpa, the apex of the prostate gland forms the greatest resistance t.> the introduction of the forceps and the extraction of the stone, and, therefore, ought to be completely divided ; (P. 7 ) but, he contends, that two, and sometimes three, lines of the substance of the base of the gland, should be left undivided ; which, be asserts, is a matter of great importance, because the untouched portion, around the orifice of the bladder, prevents the effusion, of urine, and the formation of gangrene, or fistulae, between that part and the rectum (P. 22.) After this statement of one of the great principles, which Scarpa wishes to be ob- served in the performance of the lateral operation, a question or two naturally arise. Are we then to conclude, that the plan of making a free and direct incision into the bladder ought to be abandoned ? Must we forget, that it is this method, which has an- swered so well in the hands of Cheselden and the several renowned lithotomists al- ready enumerated ? And must we believe, that the advice delivered upon this point by Bertrandi, Desault, Mr. John Bell, and all the best modern surgeons in this country, is founded only upon a capricious partiality to the free use of cutting instruments ? Earnestly as I respect the names of a Cal- Jisen and a Scarpa, their authority cannot influence me further, than I find it coincide with the dictates of experience, — the great arbitrator of every disputed point in practice. We have seen, that an apprehension of effusion of urine, gangrene, fistulae, he. is the only reason assigned by Scarpa for his aversion to making a complete division of the side of the prostate gland, and orifice of the bladder. But, I would inquire, do we find extravasation of the urine, between the rectum and bladder, and gangrene, and fistulae, so frequent after lithotomy in Eng- land, as to render it probable, that these ill consequences can ever proceed from our usual mode of dividing completely, not only the side of the prostate gland, but also the adjoining part of the bladder? Are such bad effects so often experienced in this coun- try, as to constitute a material source of un- easiness in the mind of a surgeon about to undertake lithotomy ? Do they form a sub- stantial reason for abandoning the inaxim of always endeavouring, as far as circumstances will allow, to make an incision of sufficient size for the easy removal of the calculus ? And, would not Scarpa’s method of stretch- ing and dilating the wound, in order to get the stone out of the bladder, often danger- ously prolong the operation; lead to much mischief from the repeated use of the for- ceps ; cause serious contusion and lacera- tions of the parts ; and, for all these reasons, render inflammation of the bladder and pe- ritoneum very likely to follow ? In the course of the twenty-four years that I have been in the profession of surge- ry, I have seen the lateral operation perform- ed an immense number of times, either with various kinds of gorgets, beaked knives, the lithotomie cache, or common scalpels. In all these examples the avowed intention of the surgeon was to make a free opening into the bladder. 1 do not mean, however, to say, that this was always actually accom- plished, since the bad construction of the instruments employed, and other causes, sometimes frustrated the wise design of the operator. But, what was the consequence ? Generally speaking, those surgeons who LITHOTOMY. made only a small incision into the bladder, and kept their patients a long while upon the operating table, ere they succeeded in getting out the stone, by the repeated and foicibleuse of the forceps, had the mortifi- cation to see very few of their patients re- cover : a large proportion of them being carried off by peritonitis, on the third or fourth day after the operation. On the contrary, when the incision was ample and direct, so that the calculus could be easily and gently removed, the patients were almost always saved. During the first six or seven years of the long time during which I have enjoyed fre- quent opportunities of seeing lithotomy per- formed in St. Bartholomew’s Hospital, gor- gets were invariably used, most of which instruments made an insufficient opening. The consequence was, that many of the patients were detained a long while upon the operating table, before the stone could be extracted, and some considerable num- bers were lost by peritonitis. Of late years, however, in the same institution, common scalpels and beaked knives have been often used ; a freer opening has been generally made ; and the proportion of deaths from peritonitis is strikingly lessened. The following observation, made by Mr. Martineau, is also worthy of particular at- tention : — “ In the first years of my prac- tice,” says he, “ I was not very successful ; and often witnessing many untoward circum- stances in myself and others, which appeared to arise from the use of the cutting gorget, 1 determined to lay that instrument aside, and employ the knife only, and the blunt gorget as a conductor for the forceps.” (Med. Chir. Trans,, p. 405.) Now, when we remember that this gentle- man has lost only two out of eighty-four patients, on whom he has operated, his re- marks are of great importance ; and his cases, and the other facts, which I have spe- cified, strongly impress my mind with the truth of all that I have urged, respecting the advantages of making the opening large, and in the best direction for the easy pas- sage of the stone outward. In Mr. Martineau’s manner of operating, it is true, he does not make the external wound parallel to that in the bladder, as I venture to recommend, but directs it nearly in a line with the raphe ; a circumstance which may, perhaps, account for his continu- ing the use of the blunt gorget as a conduc- tor for the forceps. Neither is his internal incision carried downwards and outwards, as Bertrandi, Desault, and many other judi- cious surgeons consider most advantageous. But these defects (if I may presume to call them so) are i-endered of less consequence by the rule, which Mr. Martineau observes, of making his first incision long and deep , and avoiding all stretching and laceration of the parts. Like Langenbeck (See First Lines of Surgery, Vol. 2,) he uses a-staff, the groove of which is much wider and deeper than usual, and therefore more easily felt. This instru- ment his assistant holds, in the way preferred 2io by Scarpa, nearly in an upright straight direction. “After the first incision (says Mr. Martineau) I look if the stall’ is not al- tered in its situation, and then feeling for the groove, I introduce the point of the knife into it, as low down as I can, and cut the mem- branous part of the urethra , continuing my knife through the prostate into the bladder .,* when , instead of enlarging the wound down- wards, and endangering the rectum, I turn the edge of the blade towards the ischium, and make a lateral enlargement of the wound in withdrawing the knife." (See Med . Chir. Trans. Vol. 11, p. 409.) This description is particularly interesting, as coming from a gentleman, who has had so much experience and success; and its value would have been increased, had the direction in which the edge of the knife was turned in the division of the prostate gland, been exactly speci- fied. With respect to the degree of importance* which ought to be attached to the fear of effusion of urine, between the bladder and rectum, gangrene, fistulae, &c., I can only- say, that they are inconveniences which are not commonly observed after lithotomy in this country. In two or three instances only I have known the urine come through the wound longer than usual, and these cases ended well. As for the extravasation of urine and sloughing, I shall merely remark, that although there cannot be a doubt of their occasional occurrence, they have not taken place after any of the numerous ope- rations, with the results of which 1 have been acquainted. All these facts and considerations, there- fore, incline me to doubt whether the appre - hension of the effusion of urine, fistulae, &c. be sufficiently serious and well-founded to make it adviseable for surgeons to relin- quish the plan of making a complete division of the side of the prostate gland, and neck of the bladder, in the operation of lithotomy. Nor is it at all clear to my mind, that effusion of urine and sloughing are likely to be the effect of practising a free opening. Indeed, whenever they do happen, I believe they proceed from a totally different cause, viz, from the incision in the skin being too small and too high up, and from the axis of the internal part of the incision not correspond- ing with that of the external wound. Hence the urine does not readily find its way out- ward, and some of it passes into the neigh- bouring cellular membrane. In confirmation of the foregoing remarks, I beg leave to cite the sentiments of one of the greatest and most experienced of modern surgeons. Speaking of the defects of Hawkins’s gorget, Desault observes, “ La methode de l’enforcer horizontalement dans la vessie sur la catheter tenu h angle droit avec le corps, a deux grands desavantages : d’un cote celui de p^netrer par l’endroit le plus retreci du pubis, et par consequent de ne faire que difficilement une ouverture suffisante; d’un autre cote, celui de ne pas etablir de parallelisme entre l’incision exte- rieure des teguraens qui est oblique et celle LITHOTOMY. 214 du col de la vessie et de la prostate, qui sc perceptible through the thin parietes ot the trouve alors horizontale. De-Ik la possibi- rectum and bladder While the latter instru- lite des infiltrations par les obstacles qui les urines trouveront k s’ecouler.” No doubt also some of the worst, and most dangerous urinary extravasations after li- thotomy. have proceeded from another cause, pointed out by the same excellent surgeon. “ Imprudemment port6 dan:> la vessie, le gorgeret peut alier par le stylet beaueoup trip long qui le term ie, heurier, dechirer, perforer merae la '/embrane de la vessi -, et donner iieukdes infiltrations d’au- tant plus daugereuses, que le lieu d’ou elles partent est plus inaccessible. Cet accident est surtout k craindre, lorsque, comtne les Anglais, on se sert de catheter sans cul-de- sac.” (See (Euvres Cliir. de Desault par Bi- chat, T. 2, p. 460, 461.) LITHOTOMY THROUGH THE RECTUM. This method may be said to have been first suggested in a work published at Bkle, in the 16th century, by an author who assu- med the name of Vegetius : “ Jubet per vul- nus recti intestini, et vesicse aculeo lapidem ejicere,” says Haller, in speaking of this wri- ter. (Bibl. Chir. Vol. 1, p. 102.) But the proposal never received much attention un- til the year 1S16, when M. Sanson, in France, gave an account of this manner of operating, and urged several considerations in favour of the practice. In that country, however, the operation has been performed only by Dupuytren, and, though the opera- tion proved successful, the other French surgeons do not appear »o have imitated him. Nor am 1 aware, that Dupuytren him- self now continues the practice. Almost as soon as this method was heard of on the other side of the Alps, it was put to the test of experience by Barbantini, in a case where every other plan of operating appeared hard- ly practicable. The connexion of the ure- thra with the rectum, prostate gland, and posterior part of the bladder, (says M. San- son) made me easily perceive, that by divi- ding the sphincter ani and some of the rec- tum near the root of the penis, I should x pose, not only the apex of the prostate gland, but a more or less considerable por- tion of this body, and that I should then be able to penetrate into the cavity of the blad- der, either at the neck through the prostate, or at its posterior part,” It was the latter method, which M. Sanson first tried upon the dead subject. The body was placed in the position usually chosen for the common ways of operating, and a staff was introdu- ced, and held perpendicularly by an assist ant. A bistoury, with its blade kept flat on the left fore-finger, was now introduced into the rectum, and the edge being turned up- wards, M Sanson, with one stroke, in the direction of the raphe, cut the sphincter ani, and the lower part of the rectum. The bot- tom of the prostate gland being thus expo- sed, the finger was next passed beyond its solid substance, where the staff was readily ment was steadily maintained in its original osition, M. Hanson here introduced the nife into the bladder, and, following the groove of the staff, made an incision about an inch in length At this instant, the flow of urine from the wound indicated that the bladder liad had an opening made in it. On examination, the parts divided were found to be the sphincter, the lower part of the rectum, the back part of the prostate, and the adjacent portion of the bladder. Ano- ther mode, contemplated by M. Sanson, was. after dividing the sphincter ani, to cut the termination of the membranous part of the urethra along the groove of the staff held perpendicularly, and by the same gui- dance to expend the incision in the median line through the prostate gland and neck of the bladder. In Barbantini’s case, the calculus was so large, that it made a considerable promi- nence in the rectum, where it was felt ex- tending across from one tuberosity of the ischium to the other. On account of its size, its extraction by the lateral operation was considered impracticable, and, as it was not thought adviseable or easy to break such a mass, and Barbantini regarded the high operation as more, difficult and uncer- tain in its results than the common method, it was determined to operate through the rectum. The attempt w T as delayed some days, by the impossibility of introducing effectually the staff', which was stopped at its entrance into the bladderby the calculus. But, as a grooved instrument was judged to be an essential guide, Barbantini caused a long director to be constructed, which he thought might be passed more conveniently than the staff, into the first incision. He aho provided himself with long forceps, the blades of which were very broad, and ad- m 1 ted of being put separately over the stone. A staff having been introduced, the operation was done after M. Sanson’s man- ner, except that a wooden gorget was intro- duced for the protection of the rectum, and the prostate gland was left undivided at the forepart of the wound. When the bladder had been opened at the lower part of the rectum, as far as the groove of the stafF served as a guide, the latter instrument was withdrawn, and the long director introdu- ced into the incision, which, under its gui- dance, was then enlarged to the necessary extent. With some difficulty the stone was then extracted, and found to weigh nine ounces and a half. For about eighteen days the urine passed away bv the anus, only a a few drops occasionally issuing from the urethra. As this circumstance gave Barban- tini some uneasiness, he introduced hiS‘ ( finger into the bladder, the inner surface of whicl), near the wound, he found covered I with encysted calculous mailer, which was j very adherent. At length, however, it was j gradually removed, with a portion of new- formed membrane, by attempts repeated LITHOTOMY. -215 with the linger several days in succession. A catheter was then introduced, through which, at first, almost the whole of the urine (lowed. But the tube being after- ward obstructed with mucus, it became ne- cessary frequently to clear it by injecting tepid water. The cure now seemed to pro- ceed with rapidity. When the feces were hard, none of them passed into the bladder ; but when they were liquid, a part of them were voided with the urine through the tube, though without any inconvenience. At the end of fifty days, s arcely any urine passed out of the wound ; the patient, therefore, went into the country, where, in the course of another month, the cure was complete. About a year ago, I saw an example, in which a calculus had made its way through the prostatic portion of the urethra, and formed, with the swelling of the soft parts, a considerable prominence within the rec- tum. If the patient had been under my care, I should certainly have made an inci- sion directly on the tumour just within the sphincter, by which means the calculus might have been removed with great ease, and less risk than dividing the prostate. However, the latter method was followed, and the case had a very favourable termina- tion. In this instance, as the sound, in its passage, only occasionally touched a small point of the calculus, which approached the urethra, and this just at the instant before its entrance into the cavity of the bladder, the exact nature of the case was for some lime a matter of doubt to several skilful surgeons who were consulted. Respecting the merits of lithotomy through the rectum, 'l think the practice well deserving the con- sideration of the profession, where the cal- culus is known beforehand to be of unusual size. It must be less painful, I apprehend, than the high operation, and, perhaps, more easy of execution. But it is difficult, with the scanty experience before us, to offer any very decided opinion whether, on the whole, it ought to be preferred either to the high or the lateral operation, by which last, stones of larger size than that extracted by Barbantini, have been successfully taken out by Mr. Mayo, of Winchester, Dr. Klein, of Stuttgard, and others. The most serious consideration is, whether a large incision, forming a communication between the blad- der and rectum, will generally heal up, as well, or even more favourably, than in Bar- bantini’s case. This is a point which can only be decided by further observation. A smaller wound in the same part, it appears, is soon cured ; for in the instance reported by Sanson, the boy was quite well on the twentieth day. For further information, consult Sanson, DcsMoyens de Parvenir a la Vessie par le Rectum, 4to. Paris , 1817 ; JV*. Barbantini Obs. relative a. Vextruction d’un calcul urinaire ires volumineux , operec au moyen de la taille vesicoreclnle, 8 vo. Lucques , 1819 ; Journ. Complem. du Did. des Sciences Med. T. 6, p. 79, 8vo. Paris , 1820 ; Diet des Sciences Med. T. 28, p. 422, LITHOTOMY IN WOMEN. Women suffer much less from the stone than men, and far less frequently stand in need of lithotomy. It is not, however, that their urine will not so readily produce the concretions which are termed urinarv <-il- culi. The reason is altogether owin to he shortness, largeness, and very dilatab na- ture of the female urethra ; circumstances which in general render the expulsion of the stone with the urine almost a matter of certainty. The records of surgery present us with numerous instances, where calculi of vast size have been spontaneous ly voided through the meatus urinarius, either sud- denly without pain, or after more or less time and suffering. Heister mentions seve ral well-authenticated examples. Middle- ton has also related a case, where a stone, weighing four ounces, was expelled in a fit of coughing, after lodging in the passage a week. Coiot speaks of another instance, where a stone, about as large as a goose’s egg*, after lying in the meatus urinarius seven or eight days, and causing a retention of urine, was voided in a paroxysm of pain. A remarkable case is related by Dr. Moli- neux in the early part of the Philosophical Transactions : a woman voided a stone, the circumference of which measured the long- est way seven inches and six-tenths, and round about, where it was thickest, five inches and three quarters ; its weight neav two ounces and a hall troy. And Dr. Yel- loly has related an interesting example, in which a calculus, weighing three ounces, three and a half drachms troy, and lodged in the meatus urinarius, was easily taken out with the fingers. (See Med. Chir. Trans. Vol. 6, p. 577.) Dr. Yelioly also refers to several very remarkable instances, described in the Phil Trans. Vols. 12, 15, 17, 20, 34, 42, and 55, proving what large stones will pass out of the female urethra, either spon- taneously or with the aid of dilatation and manual assistance. Were any doubts now left of this fact, they would be immediately removed by other histories, especially those contained in a paper drawn up by Sir A, Cooper. (See Med. Chir. Trans. Vol. 8, p. 427, 4 r C .) Sometimes, after the passage of large calculi, the patient has been afflicted with an incontinence of urine; but, in general, this grievance lasts only a short time. The occasional spontaneous discharge of very large calculi through the meatus uri- narius led Frederic de Leauson to deliver the advice not to interfere with them, as he thought they would all present themselves sooner or later at the orifice of that passage, and admit of being taken away with the fingers. (See Trait 6 Nouveau pour ai seme at parvenir a la 'Vraie Curation de plusieurs belles Operations, fyc. Geneve. 1674.) When surgeons began to consider what very large calculi were sometimes sponta- neously voided, and the large size, and di- latable nature of the female urethra, they suspected that it would be a good practice LITHOTOMY. 210 to dilate this passage by mechanical con- trivances, until it would allow the stone to be extracted, and thus all occasion for cut- ting instruments might be superseded. With this view, Tolet first proposed suddenly di- lating the passage with two steel instru- ments, called a male and female conductor, between which the fingers, or forceps, were passed for the removal of the calculus. (Traits de la Lithotomie, Paris , 1681.) But as it was afterward rightly judged, that the dilatation would produce less snffering and injury, if more gradually effected, Douglas suggested the practice of dilating the mea- tus urinarius with sponge or dried gentian root. Mr. Brom field has published the case of a young girl, in whom he effected the ne- cessary dilatation by introducing into the meatus urinarius the appendicula coeci of a small animal in a collapsed state, and then filling it with water by means of a syringe ; thus furnishing a hint for the construction of instruments on the principle of Mr. Arnott’s dilator. The piece of gut, thus distended, was drawn out in proportion as the cervix vesicae opened, and, in a few hours, the dila- tation was so far accomplished, that the calculus had room to pass out. (See Chir. Obs. and Cases, Vol 2, p. 276.) Mr. Thomas met with a case, in which, after dilating the meatus urinarius with a sponge tent, he succeeded in extracting an earpicker which lay across the neck of the bladder. The passage was so much enlar- ged, that the left fore-finger was most easily introduced, and (says this gentleman) “ 1 believe had the case required it, both thumb and finger would have passed into the blad- der without the smallest difficulty.” After adverting to this, and other facts, proving the ease with which the female urethra can be dilated, Mr. Thomas remarks : “ If these relations can be credited, and there is no reason why they should not, l can hardly conceive any case, in a young and healthy female subject, and where the bladder is free from disease, where a very large stone may not be extracted, without the use of any other instrument tnan the forceps, the urethra having first been sufficiently dilated by means of the sponge tents For this purpose, the blades of the forceps need not be so thick and strong as those commonly employed. (See Medico- Chir. Trans. Vol. 1, p. 123 — 129.) Many facts of a similar kind are on record, and one in which a large needlecase was extracted, is referred to in a modern periodical work. (See Quarterly Journ. of Foreign Med. Vol. 2, p 331.) Some surgeons have extracted stones from the female bladder in the following manner: the patient having been placed in the posi- tion commonly adopted in the lateral opera- tion, a straight staff, with a blunt end, is in- troduced into the bladder, through the mea- tus urinarius. The surgeon then passes along the groove of the instrument the beak of a blunt gorget, which instrument becoming wider towards the handle, effects n part of the necessary dilatation. The staff being withdrawn, and the handle of the gor* get taken hold of with the left hand, the right fore-finger with the nail turned down- wards, is now introduced slowly along the concavity of the instrument. When the urethra and neck of the bladder have thus been sufficiently dilated, the finger is with- drawn, and a small pair of forceps passed into the bladder. The gorget is now remo- ved, and the stone taken hold of, and ex- tracted. ( Sabatier , Medecine Opdratoire, T. 2, p. 103.) This plan, however, is liable to the objec- tions arising from the dilatation being too suddenly effected ; and the practice now generally preferred is that of gradually ex- panding the meatus urinarius with sponge tent. And, as the retention of the urine, during the continuance of the sponge, causes great irritation, I consider Mr. C. Hutchin- son's suggestion of placing a catheter in its centre, as mentioned by Sir A. Cooper, as meriting attention. (See Med. Chir. Trans. Vol. 8, p. 433.) Notwithstanding these favourable ac- counts of the practice of dilating the female urethra, for the purpose of removing cal- culi from the bladder, there are very good surgeons who deem an incision the best practice. It is certain, that some patients have found the method insufferably tedious and painful. But the strongest objection is the incontinence of urine, which occasion- ally follows any great distention of the ure- thra and neck of the bladder. Klein, one of the most experienced operative surgeons in Germany, states that he has tried both plans, and that the use of the knife is much less frequently followed by incontinence of urine. On the other hand, Mr. Thomas be lieves, that this unpleasant symptom is quite as often a consequence of the operation of lithotomy, as now usually performed. (Med. Chir. Trans. Vol. 1, p. 127.) When the stone is not very large, perhaps dilatation should be preferred ; and, in other cases, an inci- sion. In females, lithotomy is much more easy of execution, and less dangerous, than in. male subjects. It may be done in various ways ; but the surgeons of the present time constantly follow the mode of making the requisite opening by dividing the urethra and neck of the bladder. Louis employed for this purpose a knife which cut on each side, and was contained in a sheath; Le Blanc, a concealed bistoury, which had only one cutting edge ; Le Cat. his gorgeret-cys- titome ; Frere Come, his lithotome cache ; and Fleurant a double-bladed lithotome cache. Of these instruments, the best, I think, is that of Frere Come. But, at pre- sent, every surgeon knows, that the opera tion may be done, as conveniently as possi- ble, with a common director and a knife, that has a long, narrow r , straight blade. A straight staff, or director, is introduced through the mealus urinarius ; the groove is turned obliquely downwards and outwards, in a direction parallel to the ramus of tin- left os pubis ; and the knife is thus conduct* LITHOTOMY. 217 ed into (lie bladder, and makes the necessary incision through the whole extent of the passage, and neck of the bladder. Louis and Fleurant, as I have said, were the inventors of particular bistouries for di- viding both sides 'of the female urethra at once. The instrument of the former effect- ed this purpose, in passing from without inwards; that of the latter, in passing from within outwards. Fleurant’* bistoury bears some resemblance in principle to Frere Gome’s lithotome cache or to the cutting forceps, with which Franco divided the neck of the bladder. The reason assigned in recommendation of these bistouries is, that they serve to make a freer opening for the passage of large stones, than can be safe- ly made by cutting only in one direction. When the calculus is large, it is certainly dif- ficult to procure a free opening, without cut- ting the vagina, in front of which passage, there is but little space under the pubes for the removal of the stone. Hence, Dubois invented a new method, which consists in dividing the meatus urinarius directly up- wards towards the symphisis of the pubes, dilating the w r ound and keeping the vagina out of the way by means of a blunt gorget, and then taking out the calculus with the forceps. This method seems to me better devised for the protection of the vagina, than the acquirement of more room for the cal- culus, and whatever space is gained, is only gained by the distention of the parts, and the propulsion of them downwards. The plan is acknowledged to be very painful, yet generally successful, and not followed by any serious symptoms or incontinence of urine. (See Did. des Sciences, Med. T. 28, p. 43b.) When the stone is known to be very large, Sabatier and some other modern surgeons prefer the apparatus altus. A case may present, itself, in which the posterior part of the bladder, drawn down- wards by the weight of the stone, may dis- place a portion of the vagina, and make it protrude at the vulva in the form of a swell- ing. Here, there w r ould be no doubt of the propriety of cutting into the tumour, and taking out the foreign body contained in it. Rousset performed such an operation, and Fabricius Hildanus in a case, where the stone had partly made its way into the va- gina, enlarged the opening, and successfully extracted the foreign body. Mery proposed to cut into the posterior part of the bladder through the vagina, after introducing a common curved staff ; but the apprehension of urinary fistulae made him abandon the project. The existence of extraordinary circum- stances may always render a deviation from the common modes of operating not only justifiable, but absolutely necessary. Thus, Tolet met with a case, where a wo- man had a prolapsus of the uterus, with which the bladder was also displaced. In the latter viscus, several calculi were felt: an incision was made into it, and the stones extracted, after which operation, the dis- placed parts were reduced, and a speedy Voi,. If 28 cure followed. (Sabatier, Medecine 0p6ra - loirt , T. 2, p. i07.) The incontinence of urine, consequent to lithotomy in women, is by no means an unlrequent occurrence. Mr Hey cut two female patients for the stone, both of whom were afterward unable to retain their urine, and were not quite well when discharged from the Leeds Infirmary. These cases led Mr. Hey in a tliifd example lo endeavour to prevent the evil, by introducing into the va- gina a cylindrical linen tent, two inches long and one broad with a view of bring- ing the edges of the incision together, with- out obstructing the passage of urine through the urethra. The plan answered, if it be allowable to make such an inference from a single trial. (See Hep's Practical Obs. in Surgery, p. 560. Ed. 1810.) TREATMExf AFTER THE OPERATION. If the interna] pudendal artery should be wounded, and bleed profusely, the best plan is, .f possible, first to take out the stone, and then introduce into the wound a piece of firm sponge, with a large cannula passed through its centre. The expanding property of the sponge, on its becoming wet, will make the necessary degree of compression of the vessel, which lies too deeply to be tied. When there is much coagulated blood lodged in the bladder, it is customary to wash it out by injecting lukewarm water. I cannot say that it has fallen to my lot to see any cases (out of the great number which I have seen in Bartholomew’s Hos- pital,) in which death could be imputed to hemorrhage, notwithstanding the bleeding has often been so profuse, and from so deep a source, jus! after the operation, as to cre- ate suspicion that it proceeded from the in- ternal pudendal artery. Such hemorrhage generally stopped before the patient was put to bed. The majority of patients who die after lithotomy perish of peritoneal inflammation. Hence, on the least occurrence of tender- ness over the abdomen, copious veuesection should be put in practice. At the same time, eight or ten leeches should be applied to the hypogastric region The belly should be fo- mented, and the bowels kept open with the oleum ricini. The feebleness of the pulse should not deter the practitioner from using the lancet ; this symptom is only fallacious; and it is generally attendant on all inflam- mation within the abdomen. It is a curious fact, that Mr. Martineau, who has lost only 2 out of 84 patients, whom he has operated upon for the stone, should never have found it re- quisite to bleed ; but it appears to me, that, it is a much better argument in favour of the superior safety of operating with the knife and making a f: ee opening, than reason for discouraging venesection, when inflamma- tion of the peritoneum has come on, which, however, may not be this gentleman’s mean- ing, as he says, “ I believe, it will be found in adults, that death follows oftener from ex- haustion, after a tedious operation, or from despondency, &tc. than from acute disease ; (Med. Chir. Trans. Vol 11, />. 412.) a senti- r merit, which 1 am sure this gentleman would not have entertained, had he been present with me at the opening of tbd many unfor- tunate cases, which used formerly to occur in the practice with badly made gorgets in St. Bartholomew’s Hospital. Together with the above measures, the wajjrn bath, a blister on the lower part of the abdomen, and emollient glysters, are highly proper I have seen several old subjects die of the irritation of a diseased thickened bladder, continuing after the stone was extracted. They had not the acute symptoms, the inflammatory fever, the general tenderness and tension of the abdomen, as in cases of peritonitis ; but they referred their uneasiness to the lower part of the pelvis ; and instead of dying in the course of two or three days, as those usually do, who perish of peritoneal inflammation, they, for the most part, lingered for two or three weeks after the operation. In these cases, opiate glysters, and blistering the hy- pogastric region, are the best measures. In some instances of this kind, abscesses form about the neck of the bladder. Whoever wishes to acquire a perfect knowledge of the history of lithotomy should consult the following works : Ctlsus de Re M edict ). , lib. 7, cap. 26. Remarques sur la Chirurgie de Chauliac , par M. Simon de Mingelouzeaux, tom. 2. ; Bourdeaux. 1663. La legende du Gascon par Drelincourt ; Paris, 1665. Van Horne's Opuscul a Marianus de Lapide Vesicce par Incisionem exlrahendo ; 1552. G. Fair. Hildanus, Lilhotomia Vesicce, S vo. Lond. 1640. M. S. Baroliianus , De Lapide Renum. Ejusdem de Lapide Vesicce per Inci- sionem exlrahendo, 4lo. Paris, 1540. Lc Dr an , Par allele des Dfferenles Manic res de lirer la Pierre hors de la Vessie, 2 Vol. 8 ro. 1730. Sharp's Operations. Sharp's Critical Inqui- ry. Le Bran's Operations, Edit. 5 ; London, 1781. Franco's Trail6 des Ilernies, 1561. Roselus de Partu Ccesario. Traitt de la Lilho- tomie, par F. Tolet, Paris , 5 me Ed. 1708. Heister’s Surgery, Part 2. Lilhotomia Doug- lassiana, 1723. J. Douglas , Ilislory of the Lateral Operation , 4 to. Lond. 1726. Er. M. Colot , Trade de V Operation de la Taille, fyc. 12 mo Paris, 1727. Murand, Traiti dc la Taille au haul appareil, 12 mo. Paris, 1728 ./. Mery, Observations sur la Maniere de Tailler, $-e. pratiqu6e par Frere Jacques, 12wo. Pari. , 1700. Cours d' Operations de Chirurgie por Dionis. Trade des Operations par Garengeot , Tom. 2 . Morand Opuscules de Chirurgie. Bertrand i. Trait6 des Operations. Index Su- pellectihs Analomicw Ravi once ; Leidce, 1725. ,/. G. Lsemann, De Lilhotomia Celsiance Freest antice ; Helmst. 1745. Le Cat, Recueil de Pieces sur V Opdration de la Taille Part 1 ; Rouen , 1749. Cosme, Recueil de Pieces Ana- tomiques import antes sur l' Operation de la Taille ; Paris, 1751 — 1753. J. Douglas, Postscript to Hist, of the Lateral Operation ; 1726. J. Douglas , Appendix to Hist, of the Lateral Operation ; 1731. A short Historical Account of Cutting for the Stone, by IV. Che- widen, in his own last edition of his Anatomy . Falconet in Thes. Chirurg. HaVtn ; the.'. 103, T. 4, p. 196. Hartinkeil ; Tract at us de Vesicce Urinaria: Calculo, fye. 1785. Trditc Historique et Dogmatiquc de V Operation de la Taille, par J. F. L. Deschamps, 4 Tom. 8 vo. Paris, 1796. This last work is a very Com- plete amt full account of the subject up to the time of its publication, arid well merits a care- ful perusal. Richerand s Nosogr. Chir. T. 3, p. 538 , fyc. Ed. 4. Leviillt, J\ouvelle Doc- trine Chir T. 3, p. 533. John Bell's Princi- ples of Surgery . Vol. 2, Part 1. A. Burns , in Edinb. Med and Surg. Journal, January, 1808 C. Bell's Operative Surgery, Vol. 1, 1807. Sabatier, de la Medecint Ophaloire , Tom. 3. Edit. 2, 1810. Dr John Thomson'i. Observations on Lithotomy ; Edinb. 1808. Also an Appendix to a. proposal for a new manner of catling for the Slone, 8 vo. Edinb. 1810. Allan's Treatise on Lithotomy ; Edinb. 1808. Earle's Practical Observations on Ope- rations for the Stone ; 2d Ed. with an Appen- dix containing a description of an instrument calculated to improveihal operation , 8 ro. Lond. 1803. Wm. Dense . Ohs. on the different me- thods for the radical cure of the Hydrocele, fyc. Tojwhich is added a comparative view of the different methods of cutting for the Stone , fyc. 8 vo. Load. 1798. ( Euvres Chir. de Desault par Bichat ; Tom. 2. Wm. Simmons, Cases and Obs. on Lithotomy, 8 vo. Manchester, 1808. C. B. Trye , Essay on some of the Stages of the Operat ion of cutting for the Stone, 8 vo. Loud. 1811 Roux, Voyage fail a Londres en 1814, ou Par allele de la Chirurgie Angloise avec la Chirurgie Francoise, p 315, fyc. Paris, 1815. Schregtr, Chirurgisihe Versnche, B. 2. von Steinschnitlen an Weibern, p. 135, fyc. 8v o. Number”,' 1S18. C. J. M. Langenbeck, iiber tine einfache und sichcre methodcdcs Steinschnittes , 4 to. Wurzburg, 1802. F. X. Rudtorjfer, Ablmndluvg iiber die Operation des Blasensteines nach Pajolu's Methods, 4 to. Leipz. 1S08. A. Scarpa, A Memoir on the Cutting Gorget of Hawkins, §-c. Trunsl. by J. II. Wishart, 8 vo. Edinb. 1816. If. Mayo, IV. Dickenson, II. Earle, and P. M. Marli- neau in Med. Chir. Trans. Vol. 11. Klein, Tract. Ansichten bedeutendsten Operalioner, 4 to. Stulgart, IS 16. J. S. Carpue, Hist, of the High Operation, and An Account of the various Methods of Lithotomy, 8 vo. Lond. 1819. Sir E. Home on Strictures , tyc. Vol 3, 8 vo. Lond. 1821 For a minute description and delineations of the parts concerned in the operation, see Camper's Demonslrationes Anatomico-palhologirce , lib. 2. Also L. F Von Froriep iiber die Lage der Eingcweide un Becken , nebsl enter Darstellung dcrselben , 4lo. Weimar, 1815. LOTIOA LUMINIS. — ft. Aluminis purif- ^ss. Aquas distillatae Jftj. Misce. — Some- times used as an astringent injection; some- times as an application to inflamed parts. LOTH) AMMONLE ACETATE.— ft. Liq. nimnon. acetaia} ; Spirit, vin. rectil. ; Aqua} distillata}; sing. 3* v - Misce. — Proper- ties disculient. LOTIO AMMONITE MURIATE.— ft. Ammon, muriata} 3 j. Spirit, rorismarini H>j. — Has the same virtues as the preceding LOT LUM Justamond recommended it in the early stage of the milk-breast. LOTIO AMMONIA MURIATE CUM ACETO. — R. Ammon. Mur. Zss. Aceti, Spirit, vinos, rectif. sing. fbj. Misce. This is one of the most efficacious discutient lo- tions. it is, perhaps, the best application tor promoting the absorption of extravasa- tcd blood, in cases of eechymosis, contu- sions, sprains, &.c. LOTIO AMMONLE OPIATA. — R. Spi- ntusammon. comp. 3'*iss. Aqua; distilla'ae ^iv. Tinct. Opii. ^ss. Misce. Applied by Kirkland to some suspicious swellings in the breast, soda and bark being also given inter- nally. LOTO CALCIS COMPOSlTA.— -R. Aquae calcis R>j. Hydrargyri oxymuriatis 3j Misce. — Properties strongly astringent. Ringworms, tetters, and some other cutane- ous affectionsyield to this application, which however, should generally be diluted. In the latter state, it may occasionally be used as an injection for various purposes. LOTIO GALLvE. — R. Gallarum contusa- rum 3 U- Aquae ferventis ibj. To be ma- cerated one hour, and strained. — This astringent lotion is sometimes used with a view of removing the relaxed state of the parts, in cases of prolapsus ani, prolapsus uteri, &.c. LOTIO HYDRARGYRI AMYGDALINA. — R. Amygdalurum amararum ^ j. Aquas distil fRj. Hydrar^. oxymuriatis ^j. Rub down me almonds with the water, which is to be gradually poured on them ; strain the li- quor , then add the oxymuriute of mercury. Tib- will cure several cutaneous affections. LOTIO HYDRARGYRI OXYMURIATIS. — R. Hydrargyri oxymuriatis gr. ij-s. Ara- bic! gurnmi ^;s. Aquae distillptae R,j- Misce. — This is the injection of corrosive sublimate in u*e ai St. Bartholomew’s Hospital. LOTIO HYDRARGYRI OXYMURIATIS COMPOSITA — R. Hydrarg. oxyinur. gr. x. Aq. distillat. bullientis giss. Tinct. canthar. ^ss. Misce. — This was ordered by Dr. H. Smith, to be applied every night to scrofu- lous swellings. LOTIO HELLEBORI ALB!. — R. Decoct i hellebori albi R,j. Potassae sulphured ^ss. Misce. — This is occasionally employed as an application for curing tinea capitis, and some other cutaneous diseases. LOTIO PLUM BI ACE TAT IS. — R. Liq. plumbi acet 3 j- Aq. distill. JRj- Spirit vinos, tenuioris 3u- The first and last ingredients are to be mixed before the water is added. This is the'common whitewash, an appli- cation universally known. LOTIO POTASSjE SULPHURETI — R. Potassse sulph. 3'j- Aqua; distill. jRj. Misce. — It is used in the same cases as the preceding application. LOTIO OPII. — R. Opii ptirif. 3jss. Aquae dislillatae R>j Misce. — A very excellent ap- plication to irritable painful ulcers of every description. It is best to dilute it, es- pecially at first. LOTIO PICJS. — R. Picis liquids; ^iv. Calcis Zvj. Aqua; ferventis fb>ij. — To be 2i9 boiled till half the water is evaporated. The rest is then to be poured off for use. This application is sometimes employed tor the cure of tinea capitis ; it is also of singular service in removing an extensive scorbutic redness, frequently seen on the legs, accom panying old ulcers. LOTIO ZIJNCI SULPH ATI >. — R. Zinci sulphatis 3j. Aq. ferventis Ibj. Misce. This is sometimes used by practitioners in lieq of the lotio plumbi acet. It forms a good as- tringent application fora variety of cases. When diluted, by adding two pints more water, it forms the common injection, so much recommended in cases of gonorrhoea. LUES VEIN ERE A. See V EX ERE A L DISEASE. L UM B A K A BSC ES 5. Psoas Mscess. By these terms are understood chronic collec- tions of matter, which form in the cellular substance of the loins, behind the peritone- um, and descend in the course of the psoas muscle. Patients, in the incipi- ent stage of the disease, cannot walk so well as usual ; they feet a degree of uneasi- ness about the lumbar region ; but in gene- ral, there has been no acute pain, even when the abscess has acquired such a size as to form a large tumour, protruding, externally. In short, the psoas abscess is the best in- stance, which can possibly be adduced, in order to illustrate the nature of those collec- tions of matter, which are called chronic, and which form in an insidious manner, w ithout, serious pain, or any other attendant of acute inflammation. The abscess sometimes forms a swelling above Poupart’s ligament ; sometimes below it ; and frequently the matter glides under the fascia of the thigh. Occasionally it makes its way through the sacro-ischiatic foramen, and assumes rather the appearance of a fistula in ano. When the matter gravi- tates into the thigh, beneath the fascia, Mr. Hunter would have termed it a disease in, not of, the part. The uneasiness in the loins, and the impulse communicated to the tumour by coughing, evince, that the di ease arises in the lumbar region ; but, i-t must be confessed, that we can hardly ever know the existence of the disorder, before the tumour, by presenting itself externally, leads 11 s to such information. The lumbar abscess is sometimes connected with diseased verte- brae, which may either be a cause, or an effect, of the collection of matter. — The disease, however, is frequently unattended with this complication. The disease of the spine, we may infer, is not of the same nature as ihat treated of by Pott, as there is usually no paralysis. When the bodies of patients with lumbar abscesses are opened, it is found, that the matter is completely enclosed in a cyst, which, in many cases, is of course very extensive. If the contents of such abscesses were not circumscribed by a membranous boundary in this manner, we should have them spread- ing among the cells of (he cellular substance, just like the water in anasarca. The cysts are both secreting and absorbing surfaces as LITHOTOMY. is proved by the great quantity of matter, which soon collects again alter the abscess has been emptied, and by the occasional dis- appearance of large palpable collections of matter of this kind, either spontaneously, or in consequence of means which are known to operate by exciting the action of the ab- sorbents. In slx.rt, the cyst becomes the suppurating surface, and suppuration is now well ascertained to be a process, similar to glandular secretion. While the abscess re- mains unopened, its contents are always un- dergoing a change; fresh mailer is continu- ally forming, and a portion of what was pre- viously in the cyst is undergoing t lie neces- sary removal by the absoi bents. This is not peculiar to lumbar abscesses ; it is common to all, both chronic and acute, buboes and suppurations in general. It is true, that, in acute abscesses, there often has not been time for the formation of so di tinct a mem- brane as the cyst of a large chronic abscess ; hut their matter is equally circumscribed by the cavities of the cellular sub lance being filled with a dense coagulating lymph ; and though it generally soon makes its way tothe surface, it also is occasionally absorbed. The best modern surgeons make it a com- mon maxim to open very few acute ab- scesses ; for the matter natural!) tends with great celerity to the surface of the body, where ulceration allows it to escape sponta- neously ; alter which, the case generally goes on better, than if it had been opened by art. But, in chronic abscesses, the matter has not that strong tendency to make its way outward ; its quantity is continually in- creasing; the cyst is, of course, incessantly growing larger and larger; in short, the matter, from one ounce, often gradually in- creases to the quantity of a gallon. When the disease is at length opened, or bursts by ulceration, the surface oi the cyst, irritated by the change, inflames ; and its great ex- tent, in this circumstance, is enough to ac- count for the terrible constitutional disorder, and fatal consequences, which too frequently soon follow the evacuation of the contents of such an abscess. Hence, in cases of chrOnic suppurations of every kind, and not merely in lumbar abscesses, it is the sur- geon’s duty to. observe the opposite rule to that applicable to acute cases; and he is called upon to open (he collection of matter, as soon as he is aware of its existence, and its situation will allow it to be done. Certainly, if would be highly advanta- geous to have some means of a-certaining whether the vertebrae are also diseased ; for, as in this instance, the morbid bones would keep up suppuration, until their affection had ceased, and there would be no reasonable hope of curing the ab-cess sooner, it might be better to avoid puncturing it under such circumstances. The propriety of this con- duct seems the more obvious, as issues, which are the means most likely tostop and remove the disease of the spine, are also such as afford most chance of bringing about the ab- sorption of the abscess itself. However, if the collection cannot be prevented from dis- charging itself, and ulceration is at Land, it is best to meet the danger, make an opening with the lancet, in a piace at some distance from where the pointing threatens, and after- ward heal it, in the way which will be pre- sently detailed. Though we have praised the prudence of opening all chronic abscesses while small, the deep situation of the lumbar one, and the degree of doubt always involving its early state, unfortunately prevent us from taking this beneficial step in the present case. But still the principle is equally praiseworthy, and should urge us to open the tumour as soon as the fluctuation of the matter is distinct, ami the nature of the case is evident. For this purpose, Mr. Abernethy employs an ab- scess lancet. which will make an opening large enough for the discharge of those flaky substances so frequently found blended with the matter of lumbar abscesses, and by some conceived to be an emblem of the disease being scroiulous. Such flakes seem tocon- sist of a part of the coagulating matter of the blood, and are very commonly secreted by the peculiar cysts of scrofulous ab- scesses. The puncture must also be of a cer- tain fize, in order to allow the clots of blood, occasionally mixed with the matter, to escape. Mr. Abernethy considers the open- ing of a lumbar abscess a very delicate ope- ration. Former surgeons used to make large openings in these cases; let out the con- tents; leaye the wound open: the usual consequences of which were, great irritation and inflammation of the cyst ; immense dis- turbance 6f the constitution ; putrefaction of the contents of the abscess, in conse- quence of the entrance of air into its cavity; anil, too often, death. While such practice prevailed, very few, afflicted with lumbar abscesses, were fortunate enough to escape. The same alarming effects resulted from allowing the abscess to attain its utmost magnitude, and then burst by ulceration - If then a more happy train of events depend upon the manner, in which lumbar abscesses are punctured, the operation is certainly a matter of great delicacy. Until the collection is opened, or bursts, the patient’s health is usually little, or not at all impaired ; indeed, we see in the faces of many persons with such abscesses, what is usually understood by the picture of health, lleuce, how likely our professional conduct is to be arraigned, when great changes for the worse, and even death occur very soon after we have let out the matter, seemingly, and truly, in consequence of the operation. Every plan, therefore, which is most likely to prevent these alarming effects, is entitled * to infinite praise; and such, I conceive, is the practice recommended by Mr. Aber- nethy. This gentleman’s method is to Jet out the matter, and heal the wound immediately afterward by the first intention. He justly condemns all introductions of probes, and other instruments, which only irritate the edges of the puncture, and render them un- likely to grow together again. The wound LUMBAR ABSCESS is to be caret ul ly closed with sticking plaster, and it will almost always heal. These proceedings do not put a stop to the secretion of matter within the cavity of the abscess. Of course, a fresh accumula- tion takes place ; but, it is obvious that the matter, as fast as it is produced, will gravitate to the lowest part of the cyst, and, conse- quently, the upper part will remain tor a certain time undistended, and have an oppor- tunity of contracting. When a certain quantity of matter has again accumulated, and presents itself in the groin, or elsewhere, which may be in about a fortnight after the first puncture, the ab- scess is to be punctured again, in tire same manner as before, and the w ound healed in the same way. The quantity of matter will now be found much less, than what was at first discharged. Thus the abscess is to be repeatedly punctured at intervals, and the wounds as regularly healed by the first intention, by which method, irritation and inflammation of the cyst will not be induced, the cavity of the matter will never be allow- ed to become distended, audit will be ren- dered smaller and smaller, till the cure is complete. * In a few instances, the surgeon may, per- haps, be unable to pers vere in healing the repeated punctures which it may be neces- sary to make ; but, after succeeding once or twice, the cyst will probably have had sufficient opportunity to contract so much, that its surface will not now be of alarming extent. It is also a fact, that the cyst loses its irritability and becomes more indolent, and less apt to inflame, after the contents have been once or twice evacuated, in the above way. Its disposition to absorb be- comes also stronger. The knowledge of the fact, that the cysts of all abscesses are absorbing surfaces, should lead us never to.neglect other means, which Mr. Abernethy suggests, as likely to promote the dispersion of the abscess by quickening the action of the absorbents. Blisters kept open with savine cerate, issues, electricity, occasional vomits of the sulphate of zinc, are the means in st conducive to this object. When the vertebrae are diseased, issues are doubly indicated In the latter complication, the case is always dangerous. If an opening be made in the abscess, the cyst is at first more likely to be irritated, than when the bones are not diseased, and the affection of the spine is rendered much less likely to undergo any improvement, in consequence of the mere formation of an outward communication. The same bad effect attends necrosis ; in which case, the absorption of the dead bone* is always^ retarded by the presence of un- healed fistulas and sores, which lead down to the disease. Mr. Crowther succeeded , in dispersing some large lumbar abscesses without opening them. Large blisters, applied to the integu- ments covering the swelling, and kept open with the savine cerate, effected the cure. s&l When this gentleman punctured such collec tions of matter, he used a small trocar, which he introduced at the same place as often as necessary. He observes, that the aperture so made does not ulcerate, and allows no matter to escape after being dressed. I cannot, however, discover any reason for his preferring the trocar to the abscess lan- cet, except that the cannula enables the surgeon to push back with a probe any flakes of lymph, &c. which may obstruct its inner orifice. But, this is scarcely a reason, when Mr. Abernethy informs us, that the opening, made with an abscess lancet, is large enough to allow such flakes to be dis- charged ; arid when they stop up the aper- ture, a probe might also be employed to push them back. A wound made vvi h a cutting instrument will, cceteris paribus, always unite more certainly by tne first intention, than one made with such an in- strument as a trocar. Mr, t rowther may always have succeeded in healing the aper- ture ; but, I do not believe, that other prac- titioners would experience equal success. Were the tumour not very prominent, from the quantity ol matter being small, suddenly plunging in a trocar might even endanger parts, which should, on no account, be in- jured. Some writers recommend opening lumbar abscesses with a seton. The matter being made to form as prominent a swelling as possible, by pressing the abdomen, and putting the patient in a position, which will make the contents of the abscess gravitate towards the part where the seton is to be introduced, a transverse cut is first to be made in the integuments down to the fascia. A flat trocar is next to be introduced within the incision, which should only be just large enough tp allow the instrument to pass freely up under the skin, for at least three quarters of an inch ; when the hand is to be raised, and the trocar pushed obliquely and gently upwards, till the cannula is within tile lower part of the sac. The trocar must now be withdrawn, and the matter allowed to flow out gently, stopping it every now and then for some minutes. The assistant must now withdraw his hand, to take away the pressure, and the thumb of his left hand upon the opening of the cannula, holding it between his fore and middle fingers. It must then be pushed upward, nearly to the top of the tumour, where its end may be distinctly fell with the fore-finger of the right hand. As soon as it can be plainly felt, it must be held steadil} in the same position, and the trocar is to be introduced into it again, and pushed through the skin, at the place where it is felt and the cannula along with it. The trocar being next withdrawn, a probe with a skein of fine soft silk, dipped in oil, must be passed through the cannula, which being now taken away, leaves the seton in its place. A pledget of mild oint- ment is then to be applied over the two openings, the more completely to exclude the air. A fresh piece of the silk is to he <>.) I MAMMA. drawn into the abscess, ami that which was in before cut off, as often as necessary. (See Latta's System of Surgery, Vol. 3, p. 307.) Mr. Crowther states, that Deckers, who wrote in 1696, discharged a large abscess, in a gradual manner, with a trocar, the cannula of which was not withdrawn, but was stopped up with a cork, and the latter let out at intervals. B. Bell also advises the cannula not to be taken out. I cannot quit this subject without mention- ing a remarkable case of lumbar abscess, which 1 once saw in Christ’s Hospital, under the care of the late Mr. Ramsden. The tumour extended from the ilium and sacrum below, as high up as the ribs. The diameter of the swelling from behind forward, might be about six or eight inches. It was attended with so strong a pulsation, corresponding with that of the arteries, that several emi- nent surgeons in this city considered the case as an aneurism of the aorta. After some weeks, as the tumour increased in size, the throbbing of the whole swelling gradu- ally became fainter and fainter, and at length, could not be felt at all. The tumour was nearly on the point of bursting. Mr. Ramsden suspected that it was an abscess, and determined to make a small puncture in it. The experiment verified the accuracy of his opinion ; a large quantity of pus was evacuated as intervals ; but the boy’s health suffering, he went to his friends at Newbury, and I did not afterward hear the event. 1 have never seen any popliteal aneurism, whose pulsations could be more plainly seen, and strongly telt, than those of the abscess we have just been describing. A singular case is related by Mr. Wilmot of a psoas abscess, the matter of which was at length absorbed, and its cavity filled with air, attended with a considerable increase in the size of the tumour, a conical elongated shape, and elastic feel, instead of a fluctua- tion, previously quite evident, and the subsi- dence of all the hectical symptoms. A complete dispersion of the swelling was effected by a bandage and compress wet with a strong decoction of oak bark and alum. (See Trans, of the King's and Queen's College of Physicians in Ireland, Vol.2,p. 26, tyc. 8co. Dublin, lbIS. F. Schoenmczel, Obs. de Musculis Psoa et lliaco suppurntis , Frank. Del. Op. V. R. Beckwith de Morbo Psoadico. Edinb. 1784. Abernethy's Surgical and Physiological Essays, Part 1 and 2. Crowther' s Observations on White- Swelling, ^c. 1808. Latta's System of Surgery , Vol. 3. Callisen's Syslema Chirurgioe Hodi ernes, Vol. 1 ,p. 370. Pearson's Principles of Surgery, p. 102, Edit. 2. Richter's Anfangsgrunde der Wundarzneykunst, B. 5, 1 13; Gottingen , 1801.) LUNAR CAUSTIC. (See Argentum ni- tratum.) LUPUS. See Noli me tangere. LUXATION. See Dislocation. Ifc/TAMMA, REMOVAL OF. The opera- ill. ration of cutting away a diseased breast, is done nearly in the same manner as the removal of tumours in general, and is indicated whenever the part is affected with an incurable disease, which admits, how- ever, of being entirely removed with the knife. When the breast is affected with scirrhus, or ulcerated cancer, the impru- dence of tampering with the disease cannot be too severely censured. Were the disor- der unattended with a continual tendency to increase, some time might properly be dedicated to the trial of the internal reme- dies, and external applications, which have acquired any character for doing good in these unpromising cases. But, unfortunately, by endeavouring to cure the disease by medicine, we only afford time for it to in- crease in magnitude, and, at length, attain a condition, in which even the knife cannot be employed so as to take away the whole of the diseased parts. When the case is marked by the characteristic features of scirrhus, noticed in the article Cancer, the soouer the tumour is cut out, fb^ietter. There are also some malignant kiYra's*5.f,sar coma, to which the female breast is subject, (as will be explained in the article Tumour,) which cannoi be removed at loo early a period after their nature is suspected, or i/i known. Indeed, though there is not equal urgency for the operation when the tumour is only an indolent, simple, fatty, or sarco- matous disease, yet as all these tumours are continually growing larger, and little success attends the attempt to disperse them, the practitioner should never devote much time to the trial of unavailing medicines and applications, and let the swelling attain a size, which would require a formidable operation for its excision. Besides, many simple, fleshy, indolent tumours, are accom- panied with a certain degree of hazard of changing into very malignant forms ol disease. It is not meant to be denied, however, there are many swellings and indurations of the breast, which it would be highly injudi- cious and unnecessary to extirpate, because they generally admit of being discussed. Such are many tumours, which are called scrofulous, from their affecting patients of this peculiar constitution ; such are nearly all those indurations which remain after a sudden and general inflammatory enlarge- ment of the mamma ; such are most other tumours, which acquire their full size in a few days, attended with pain, redness, Lc. ; and, of this kind, also, are the hardnesses in the breast, occasioned bv the mammary abscess. 'MAMMA. 2iid to the removal ot' all malignant or cance- rous tumours, their nature makes it neces sary to observe one important caution in the operation, via. not to rest satisfied with cutting away the tumours just at their cir- cumference ; but to take away also a con- siderable portion of the substance in which they lie, and with which they are surrounded. In cutting out a cancerous breast, if the ope- rator were to be content with merely dissect- ing out the disease, just where his eyes and lingers might equally lead him to suppose its boundary to be situated, there would still be left behind white diseased bands, which radiate from the tumour into the sur- rounding fat, and which would inevitably occasion a relapse. In a vast proportion of the cases also, in which cancer of the breast unfortunately recurs after the operation, it is found that the skin is the part, in which the disease makes its reappearance. Hence the great prudence of taking away a good deal of it in every case suspected to be a truly scirrhous or cancerous disease. This may also be done so as not to prevent the impor- tant objects of uniting the wound hy the first intention, and covering the whole of its sur- face with sound integuments. So frequent- ly does cancer recur in the nipple, whenever it does recur any where, that many of the best modern operators always make a point of removing this part in every instance, in which it is judged expedient to take away any portion of the skin at all. The surgeon, indeed, would be inexcusable, were he to neglect to take away such portion of the in- teguments covering scirrhous tumours, as is evidently affected, appearingto bediscolour- ed, puckered, and closely attached to the diseased lump beneath. Nor should any gland, in the axilla, at all diseased, nor any fibres of the pectoral muscle, in the same state, be ever left behind. There is no doubt, that nothing has stamped operations for can- cers with disrepute, so much as the neglect to make a free removal of the skin, and •parts surrounding every side of the tumour. Hence, the disease has frequently appeared to recur, when, in fact, it has never been thoroughly extirpated ; the disease, though entirely a local affection, has been deemed a constitutional one ; and the operation frequently rejected as ineffectual and use- less. But, strongly as I have urged the pru dence, the necessity of making a free remo- val of the skin covering, and of the parts surrounding, every cancerous or malignant tumour, the same plan may certainly be re- garded as unnecessary, and therefore, unsci- entific, in most operations for the removal of simple, fatty, fleshy, or encysted tumours, to which the breast and almost every other part are liable. However, even in the lat- ter cases, when the swelling is very large, it is better to take away a portion of skin •, for, otherwise, after the excision of the tu- mour, there would be a redundance of in- teguments, the cavity of which would only serve for the lodgment of matter. The loose superfluous skin also would lie in folds, and not apply itself evenly to the parts beneath, so as to unite favourably by the first intention ; nor could the line of the cicatrix itself be arranged w ith such nice evenness as it might be, were a part of the redundant skin taken au r ay at the time of operating. The best method of removing a diseased breast is as follows : The patient is usually placed in a sitting posture, well supported by pillows and assistants ; but the operator will find it equally convenient, if not more so, to remove the. tumour with bis patient in a recumbent position ; and this posture is best whenever the operation is likely to be long, or much blood to be lost, which circumstances are very apt to bring on fainting. I remember that Mr. Abernethy, in his lectures, used to recommend the latter plan ; which, however, without the sanction of any great name, or authority, possesses such obvious advantages, as will always en- title it to approbation. The arms should be confined back, by placing a stick between (hem and the bo'dy, by which means, the fibres of the great pectoral muscle will he kept on the stretch, a state most favourable for the dissection of the tumour off its surface The stick also prevents the patient from moving her arm about, and interrupting the progress of the operation. When the tumour is not large, and only a simple sarcoma, free from malignancy, it will be quite unnecessary to remove any of the skin, and, of course, this need only be divided by one incision, of a length propor- tionate to the tumour. The cut must be made with a common dissecting knife; and as the division of the parts is chiefly accom- plished with the part of the edge towards the point, the instrument will be found to do its office best when the extremity.of the edge is made of a convex shape, and this part of the blade is turned a little back, in the way in which dissecting knives are ’now often constructed. 1 he direction of the incision through the skin should be made according to the greatest diameter of the tumour to be removed, by which means it will be most easily dissected out. The direction of the incision is various with different practitioners ; some making it perpendicular, others transverse. In ge- neral, the shape of the tumour must deter- mine which is the best. In France, it has been said, that when the incision follows the second direction, it heals more expedi- tiously, because the skin is more extensible from above downward, than laterally, par- ticularly towards the sternum, and conse- quently allows the sides of the wound the more readily to be placed in contact ; and that the action of the pectoral muscle tends to separate the edges of the wound when it is perpendicular. On the other hand, it is allowed that the wound, made in the latter manner, is the most favourable for the escape of the discharge, if suppuration should occur. (See (Euvres (h Desault var Bichat , p, 312. T. 2.Y MAMMA. sm The cut through the skin should always be somewhat longer than the tumour ; and as it is perhaps, the most painful part of the operation, and one attended with no danger whatever, it should be executed with the utmost celerity, pain being more or less dreaded, according to its duration, as well as its degree. The fear, however, of giving pain, has probably led many operators to err, in not making their first incision through the integuments large enough, the conse- quence of which has often been that there was not sufficient room for the dissection of the tumour with facility ; the patient has been kept nearly an hour in the operating room, instead of five minutes, and the sur- geon censured by the spectators, as awk- ward and tedious. It is clear also, that, besides the great deal more blood lost, from this error, than would otherwise happen, the vessels being commonly not tied till all the cutting is finished, the avoidance of pain, that fear, which led to the blunder, is not effected, and the patient suffers much more, and for a much longer time, in conse- quence of the embarrassment and obstacles in the way of the whole operation. When the disease is of a scirrhous or ma- lignant nature, the skin covering the tu- mour should at all events, be in part remo- ved. As I have said before, all that portion which is discoloured, puckered, tubercula- ted, or otherwise altered, should be taken away. Some must also be removed, in order to prevent a redundance, in all cases in which the tumour is large. We have said too, that in cases of scirrhus and cancer of the breast, the nipple is considered a dangerous part to be left behind. For the purpose of removing the necessary portion of skin, the surgeon must obviously pursue a different mode from that above described; and, instead of one straight incision, he is to make two semicircular cuts, one immedi- ately after the other, and which are to meet at their extremities. The size of these wounds must be determined by that of the disease to be removed, and by the quantity of skin, which it is deemed prudent to take away ; for the part, which is included in the two semicircular cuts, is that which is not to be separated from the upper surface of the swelling, but taken away with it. The shape of the two cuts together may approach that either of a circle or oval, as the figure of the tumour itself may indicate, as most convenient. The direction of the incisions is to be regulated by the same consideration. In the above ways, (he first division of the integuments is to be made in removing tu- mours of every description, covered with skin. The same principles and practice should prevail in all these operations; and, whether the swelling is the mamma, or any other diseased mass, whether situated on the chest, the back, the head, or extremities, the same considerations should always guide the operator’s hand The incision, or incisions, in the skin having been made, the next object is to detach every side of the tumour from its connexions, and the separation of its ba3e will then be the last and only thing remain- ing to be done. When the tumour is a scirrhus, or other malignant disease, the operator must not dissect close to the swell- ing, but make his incisions on each side, at a prudent distance from it, so as to be sure to remove, with the diseased mass, every atom of morbid mischief in its vicinity. But when the tumour is only a mere fatty, or other mass, perfectly free from malignancy, the cellular bands and vessels forming its connexions, may be divided close to its circumference. It is astonishing with what ease fatty tumours are removed, after the necessary division is made in the skin ; they may almost be turned out with the fingers, without any cutting at all. When they have been inflamed, however, they are then more adherent to the surrounding parts. Thus we see, that the first stage of the operation of removing a tumour, is the divi- sion of ttfe skin ; the second, the separation of the swelling from the surrounding parts on every side ; the third and last stage is the division of the parts to which its under surface, or base, is attached. The latter object should be accomplished by cutting regularly from above downward, till every part is divided. It is a common thi«g to see many opera- tors constantly embarrassed and confused, whenever they have to remove a large tu- mour, on account of their having no parti- cular method in their proceedings. They first cut a few fibres on one side, then on another ; and, turning the mass of disease now to this side, now to that, without any fixed design, they both prolong the opera- tion very tediously, and present to the bystanders a complete specimen of surgical awkwardness. On the contrary, when the practitioner divides the cutting part of the operation into the three methodical stages above recommended, in each of which there is a distinct object to be fulfilled, he pro- ceeds with a confidence of knowing what he is about, and soon effects what is to be done, with equal expedition and adroitness. Having taken out the tumour, the operator is immediately to tie such large vessels as may be pouring out their blood ; indeed, when the removal of the swelling will ne- cessarily occupy more than three or four minutes, it is better to tie all the large arte- ries as soon as they are divided, and then proceed with their dissection. This was the celebrated Desault’s plan, and it is highly deserving of imitation in this country, not only because many subjects cannot afford to lose much blood, but also because the profuse effusion of this fluid keeps the ope- rator from seeing what parts he is dividing. The largest arteries being tied, the surgeon should not be immediately solicitous about tying every bleeding point which may be observed. Instead of this, let him employ a little while in examining every part of (he surface of the wound, in order to ascertain that no portion of the swelling, no hardened' lump, nor diseased fibres remain behind. MAMMA. !Evcn if any part of the surface of the pec- toral muscle should present a morbid feel, or appearance, it must on every account be cut away. Also, if any of the axillary glands are diseased, the operator should now proceed to remove them. After the time .spent in such measures, many of the small vessels, which bled just after the excision of the swelling, will now have stopped, the necessity for several ligatures will be done away, and, of course, the patient saved a great deal of pain, and more of the wound be likely to heal by the first intention. Some information may be derived, res- pecting whether any of tbe tumour is left behind, by examining its surfaces, when taken out, and observing whether any part of them is cut off ; for, if it is, it may always be found in the corresponding part of the wound. The axillary glands may invariably be taken out without the least risk, if the plan pursued by Desault in France, and the late Sir Charles Blicke, and other eminent sur- geons in this country, be adopted. The method alluded to is, after dividing the skin covering the gland, and freeing the indura- ted part from its lateral connexions, to tie its root, or base, by which it is connected with the parts on the side towards the cavity of the axilla Then the indurated gland itself may be safely cut off, just above the ligature. Were the gland cut off in the first instance, the artery which supplies it with blood would be exceedingly difficult to tie, on account of its deep situation ; and by reason of its shortness and vicinity to tbe heart, it would bleed almost like a wound of tbe thoracic artery itself. In this way, there is also not the least hazard of injuring the latter vessel. It would be a great improve- ment in the mode of operating for tbe re- moval of these glands, if surgeons were always to make the patient lie down, with the arm placed in such a position as would let the light fall into the axilla. How much the steps of the operation would be facili- tated in this way, I need not attempt to explain. The above directions will enable a sur- geon to remove tumours in general. They apply also in a great measure to encysted tu- mours ; but, a few particular rules how to operate in the latter cases, will be found in the article Tumours. One half of each liga- ture is always to be cut off before dressing the wound. The edges of the incision are to be brought together with strips of adhesive plaster ; and, before this can be done with ease, the stick confining the arm back must be removed, and the os brachii brought for- ward, so as to relax the pectoral muscle, and integuments of the breast. No sutures should ever be employed, as they are useless, pain- ful, and irritating. The wound being closed with sticking plaster, and a pledget of simple cerate, a compress of folded linen, or flan- nel, may be put over the dressings ; these are to be secured with a broad piece of linen, which is to encircle tbe chest, be fastened with pins, or stitches, and kept from slipping VoL. II 29 down by two tapes, one of which is to go from behind forward, over each shoulder, and be stitched to the upper part of the bandage, both in front and behind. The arm on the same side as that, on which the operation has been done, should be kept perfectly motionless in a sling; for, every motion of the limb must evidently disturb the wound, by putting the great pectoral muscle into action, or rendering its fibres sometimes tense, sometimes relaxed. It is scarcely ne- cessary to say, that, after so considerable an operation as the removal of a large breast, or any other tumour of magnitude, the pa- tient should be given about thirty drops of the tinctura opii. A smaller dose always creates restlessness, headach, and fever, af- ter operations, instead of having the desi- red effect. Here it becomes me to state, that as I could not find in any surgical book with which I am acquainted, what I conceived to be a proper description of the mode of re- moving a diseased breast, and tumours in general, the foregoing remarks are given chiefly on my own authority. Whetherthey are just, or not, must he decided by the pro- fession. The removal of a diseased breast rarely proves fatal of itself, unless the parts cut away extend to a considerable depth, and occupy a very large space, or the patient is much reduced before the operation. How- ever, about two years ago, a patient in St. Bartholomew’s Hospital died, without any very apparent cause, very soon after being operated upon ; and Schmucker has record- ed an instance, in which the operation was followed by tetanus. ( Wahmehmungen. B. 2, p. SO.) W ith respect to the average success, fol- lowing the removal of cancerous diseases, this is a topic, which has been noticed in the article Cancer. The statement lately made by Baron Boyer is exceedingly unfavoura- ble ; for, in one hundred cases, in which he has removed the diseased parts, only four or five of the patients continued radically cu- red. ( Traile des Mai. Chir. T. 7 p. 237, 8 ro. Paris, 1821.) The principal writers on the removal of the mamma are, Garengeot, Dionis, Le Dran, Bertrandi, Sharp, and Sabatier, in their res- pective treatises on the operations. B. Bell, Latta, &,c. have also treated on the subject in their Systems of Surgery ; and there is a memoir Sur V Operation du Cancer au Sciiiy in Les (Euvres de Desault par Bichat. T. 2. MAMMARY ABSCESS. Milk' Mscess. With regard to inflammations of the mamma, as my friend, Mr. James has observed, there is “ either simple phlegmon, or mammary abscess, which, as it depends upon a peculi- arity of state and function, ought to stand alone. Mr. Hey alsp describes a deep-seat- ed abscess, to which this gland is liable, of rather a chronic character, and is the same, perhaps, as that which Dr. Kirkland has de- scribed as the encysted. Dr. K. describes also two others, under the titles of chronic and encysted.” Certain cases most frequent* MAMMA. 226 ly occurring in unmarried females, and ha- ving very little tendency to suppuration, Mr. James suspects, are the result of inflam- mation of the gbmdular part of the breast from disorder in the digestive organs, uterine system, or both. (On Inflammation, p. 171.) Women who suckle are particularly sub- ject to inflammation and suppuration in the breast. The part enlarges, becomes tense, heavy, and painful. The integuments of the breast sometimes assume an uniform red- ness ; sometimes they are only red in parti- cular places. The inflammation may affect the mammary gland itself, or be confined to the skin and surrounding cellularsubstar.ee. In the latter case, the inflamed part is equally tense ; but, when the glandular structure of the breast is also affected, the enlargement is irregular, and seems to consist 6f< one or more large tumours, situated in the sub- stance of the part. The pain often extends to the axillary glands. The secretion of the milk is not always suppressed, when the in- flammation is confined to the integuments, and suppuration is said to come on more quickly, than in the affections of the mam- mary gland itself When the symptoms of inflammation continue to increase for four or five days, suppuration may be expected ; unless the progress of the inflammation be slow, and its degree moderate, in which cir- cumstances, resolution may often be obtain- ed, even as late as a fortnight after the first attack. Inflammations of the breast are almost always attended with symptoms of the sympathetic inflammatory fever. (See Fevers, Surgical .) 1 think authors err, who describe the febrile disorder as generally preceding the local complaint Women are most liable to mammary ab- scesses within the first three months after parturition , but they are also very much exposed to the disorder as long as they con- tinue to suckle. The most common causes occasioning the mammary abscess, as enumerated by writers in general, are, repressing the secretion of milk at an early period, mental disturbance, fright, &c. ; exposure to cold, moving the arms too much while the breasts are very large and disteuded, bruises, and other ex- ternal injuries. The causes are not always obvious. The matter is sometimes contained in one cyst, or cavity ; sometimes in several ; but the abscess generally breaks near the nipple. As all inflammations of the mamma are attended with considerable induration, these cases should be carefully distinguished from other swellings of a more incurable kind. Jt is said, that scrofulous tumours of the mamma, which have existed a long while, often disappear after the occurrence of a milk abscess. Women who have never been pregnant are sometimes affected with suppuration in the breast, supposed by Mr. James, of Exeter, to be connected with ute- rine, or gastric disorder. Even men are suiti to be. liable to similar complaints. In the early period of the affection, reso- lution should be attempted. The following are the principal means for this purpose : — topical blood-letting, saline purges, low diet, keeping the inflamed breast from hang- ing down, gentle friction of the breast, w ith a soft sponge, wet w itb some w arm emollient liquor ; having the milk tenderly sucked out at proper intervals ; saturnine applications, or lotions containing the muriate of am- monia VY hen matter cannot be prevented from forming, an emollient poultice is the best application, and the abscess should in gene- ral be allowed to break of itself unless of a somewhat chronic nature, in . hich case it should be opened in a depending part with a lancet. Sinuses sometimes form, in con- sequence of abscesses in the breast, and will not heal till freely opened with a director and curved bistoury. When the cavity of the abscess begins to fill up with granula- tions, the poultice may be left oft', and su- perficial dressings applied. The indurations, often remaining in the breast, in consequence of acute inflamma- tion and abscesses, generally yield to fric- tions with camphorated mercurial ointment, the application of a piece of soap plaster, and the exhibition of calomel, cicuta, and other alteratives. Mr. Hey describes a very deep-seated ab- scess of the breast, not of frequent occur- rence, and not confined to pregnant nor suckling women. Its situation renders all superficial applications ineffectual. The inflammatory stage is tedious ; and when the matter has made its way outward, the discharge continues, and there is no ten- dency to healing. Sometimes the matter lodges behind the mamma, as well as in the substance of the gland, and breaks out in different places, the intermediate parts of the breast feeling as if affected with a scirrhous hardness. There are numerous sinuses run- ning in different directions, and, when opened, a soft purple fungus appears w ith- in them. The disease goes on in this state for a long while, keeping up hectic symp- toms. Mr. Hey’s practice is to trace the course of all the numerous sinuses, and lay them open, and, unless this be done, with respect to every one of them, the cure cannot be accomplished. If he finds any two sinuses running in such directions, that when fully opened, they leave a small part of the mam- ma in a pendulous state, be removes such part entirely. As the sinuses are filled with fungus, their continuations present no visi- ble cavity, and can only be detected by the greater softness of parts of the w ouud, w here, on breaking down the fungus, the orifice of the collateral sinus may be found. Mr. Hey has found, that even in the most un- favourable subjects the wounds heal quickly, and the natural shape of the breast is pre- served. Consult Pearson's Principles of Surgery , chap 3. Iiey's Practical observations, p. 604. Kirkland has also treated of several kinds of abscesses of the breast, in his Inquiry into Hit present State oj Medical Surgery , Vol MERCURY. 227 2, p. 161. Callisen's Syslema Chirurgicc IIo- ditrrue , Vol. 1, p. 332. Gibbons , De Mulie- brum Alain mis tt Morbis quibus obnoxice sunt, St’o. Edinb. 1775. «/. Clubbe , Treatise on the Inflammation of the Breasts, peculiar to Ly- ing-in Women, fyc. 8 vo. Ipsivich, 1799. M. Under wood, Treatise upon Ulcers , fyc. and on the Mammary Abscess, fyc. 8ro. Land 1783. J. H. James, on the Principles of Inflamma- tion, p. 171, 8vo. Lond. 1821. Boyer, Traiti des Mai. Chir. T. 7, p. 211,4-c. 8vo. Parh, scurfy exfoliations, not unlike those observed in rubeola. This desquamation has not been attended to by Dr. Moriarty or Mr. Alley, if they have not, by giving the same naras to the decrustation which occurs in the last stage, confounded both together. It commences in those places where the eruption first made ils ap- pearance, and in this order spreads to other parts. About this period the fauces become sore, the tongue swells, and the eyes appear somewhat inflamed. “The duration of this stage is very va- rious; sometimes it continues from ten to fourteen days, and, in oilier cases, it termi- nates in half that time. When she disease has appeared in ils mildest form, the patient recovers immediately after the desquamation, a new cuticle having formed underneath; but, if severe, he has onty experienced the smallest part ot his sufferings, and the skin now assumes a new appearance, which I have considered as the second stage. “ t he skin at this period appears as if studded with innumerable minute vesicles, which are fi led with a pellucid fluid. These vesicles may be expected, if the patient, at the close ot the first stage, complains ot in- crease! itching, and sense of burning heat, in those parts Irom which the cut icuiar ex- foliations have fallen. They rein fin some- times tor a day or two, but ate most com- moidy burst, immediately after their forma- tion, by the patient rubbing them, in order to relieve the troublesome iichiness with which these parts ate affected. They dis- charge a serous, acrimonious fluid, which possess such a very disagreeable odour as to induce nausea in the patient himself, and thuse who approach near his bedside. The odour is so peculiar, that it can easily be re- cognized by any person who has once ex- perienceu it. “This fluid is poured out most copiously from the scrotum, groin, inside of the thighs, or wherever the skin forms folds, and seba- ceous glands are most numerous. The serous discharge from these minute vesicles forms, with the cuticle, an incrustation, which may be considered as the third or last state. ‘‘ These crusts are generally very large, and, when detached, retain the figure of the parts from which they have lallen. Their colour is yellowish; but sometimes appears dark and dirty, this period of the disease might be termed, ! ;hink, with much pro- priety, the '.ta„e 61 decrustation, in order to distinguish n more imiy troui the desquama - tion, which has been a< ready notic.d. From the u.-e of the two last terms indi- runi- nately , tbos who have described the d siase have introduced into their descriptions a degree ul confusion which has caused its progress not to be well understood. When this stage appears, the fauces become more affected, T>e ey< s intolerant of light, end the tarsi tender, inflamed, and sometimes in- verted. The crusts torm< d on the face, as in other parts ot the body, before tailing off, divide asunder, so as to leuv*-: cracks and fissures, which produce an hideous expres- sion ot countenance ; and the eyelids are also, from the general swelling of the lace, completely closed. The back und hairy scalp are last affected, and, even in very severe cases, these parts are sometimes ob- served to escape entirely. The patient. MERCURY m whilst in this state, is compelled to desist from every kind of motion, on account of tile pain which he experiences on the slight- est exertion, and which he describes as if his flesh were cracking. The crusts also fall off in such abundance, that the bed appears as it strewed with the cones of hops. Whilst the eruption is only making its appearance in one place, another part may have arrived at its most advanced form ; so that all the dif- ferent stages ot the disease may he present atone lime in the same individual. It is attended with typhus through its entire course } but it is very curious to observe, that the appetite for food, in most cases, re mains unimpaired, and sometimes is even voracious. This circumstance was particu- larly remarkable in a patient who laboured under the disease, in its worst form. for the space of three months, in the Royal Infirm ary of Edinburgh ; for double the usual hos- pital allowance of food was scarcely suffi- cient to satisfy his hunger. When the catarrhal symptoms have continued during the progress of the complaint, they are, at this advanced period, particularly aggrava- ted : the anxiety and pain of the breast are also very severe, attended with cough, and bloody expectoration, and the patient always feels languid and dejected. The pulse be- comes frequent, feeble, and irregular, the tongue black and parched, and at length diarrhoea, delirium, convulsions, gangrene of the surface of the body, and death, super- vene. In its mild form, it only goes through the first stage, and terminates, as we have already stated, in a few days, by a slight desquamation. But, when severe, it is often protracted more than two months, every stage of the eruption continuing proportion- abiy longer} and when, in this manner, it has run its course, it repeatedly breaks out on the new surface, and passes through the same stages.” (M'Mullin in Edinb. Med. and Surg. Journal, No. 5.) With respect to the remote cause, this is the employment of mercury. Dr. M‘Mullin is inclined to believe with Dr. Gregory, that the application of cold to the body, while under the action of mercury, is absolutely necessary, for its production; an opinion strengthened by the constant prevalence of catarrhal symptoms. However, Mr. Pearson thinks, that cold has no concern in bringing on the complaint in patients under the influ- ence of mercury. At the same time it merits particular attention, that the disease is not exclusively occasioned by mercury either in its general, or more partial attacks: it has been observed to follow exposure to cold, and to recur in the same individual, at irre- gular intervals, without any obvious or ade- quate cause. ( Bateman's Synopsiq, p. 256, Ed. 3 ; Rutter in Edin. Med. and Surg. Journ. Vol. 5, p. 143 } Marcet in Med. Chir. Trans. Vol. 2, art. 9.) In the early stage, Mr. Pearson recom- mends small doses of antimonial powder, with saline draughts, or the ammonia acetata. A genlle purgative should be given every three or four days, and opium to procure sleep. The latter medicine sometimes dot ■ most good, when joined with camphor, or Hoffman’s anodyne liquor. Sarsaparilla and bark may be given, when the discharge is no longer ichorous, and the tumefaction has subsided. Vitriolic acid lias seemed to give relief. The diet may be light and nutritive, without fermented liquors, however, till the desquamation has somewhat advanced. Fre- quent use of the warm bath, and often chan- ging the patient’s linen and sheets, which soon become stiff and rough with the dis- charge, afford much benefit. If the warm bath cannot be had, Mr. Pearson advises washing the body very tenderly with warm water-gruel ; he also covers parts, from which the cuticle is detached, with a mild cerate, and renews the application twice a day. (. P . 178.) Dr. M‘Mullin advises the immediate dis- continuance of mercury ; the removal of the patient from wards, where this mineral is in use ; emetics and diaphoretics ; but on account of the very irritable state of the bowels, he says antimonials are hardly ad- missible, and that when purgatives are indi- cated, only the mildest ones, such as ol. ri- cini, sulphate of magnesia, &c. ought to be given. He advises mucilaginous draughts with opium for relieving the soreness of the fauces. In the second stage, the cold infu- sion of bark with aromatics and opium, or what is more praised, wine, porter, &c. To relieve the ophthalmia tarsi, the unguentum oxidi zinci, and to appease the painful sensa- tion of the skin cracking, the linimentum calcis, which should be liberally applied as soon as crusts appear. Consult Essay on a Peculiar Eruptive Dis- ease, arising from the Exhibition of Mercury , by G. Alley , 8vo. Dublin , 1804 ; also Ubser- vaiions on the Hydrargyria , or that Vesicular Disease arising from the Exhibition of Mer- cury, 4to. Land. 1810. A Description of the. Mercurial Lepra, by Dr. Moriarty , 12mo. Dublin , 1804. SpensandJ WMullin, in Edin- burgh Med. and Surgical Journal, No. 1, and 5. Pearson on Lues Venerea, Edit. 2. Rate- man's Synopsis, p. 256, fyc. Ed. 3. Frictions toith Mercurial Ointment. No metal acts in its pure metallic state ; it must first be more or less combined with oxygen. The mercury, contained in the unguentum hydrargyri, becomes in a cer- tain degree oxydated, when triturated for the purpose of blending it with the fat. The metal, however, in. mercurial ointment, is in the most simple, and least combined form, of all its preparations, and hence, it not ortly generally operates with more mildness on the system, but with more specific effect on the disease. Various salts of mercury, when given internally, operate more quickly than mercurial frictions ; yet there are many practitioners, who do not like to confide solely in any internal preparations for curing the venereal disease, particularly, when the virus has produced effects in consequence of absorption. We shall only just mention in this part of the work, that rubbing in MERCURY. 233 mercurial ointment is the mode of affecting the system with mercury, which is gene- rally considered to agree best with most constitutions, and to act with most certainty on the venereal disease. Mercurial Fit migatio ns. We have mentioned this method, as being one of the most ancient plans of affecting the constitution with mercury, and Lalo- nette and Abernethy have stated circum- stances in its favour, which certainly render it sometimes a very eligible mode. The latter is of opinion, that if the peculiar ad- vantages of mercurial fumigations were ge- nerally known to practitioners, they would be much more frequently employed. The advantages of the method consist in its af- fecting the constitution, when other means have failed, and in producing its effects in a much shorter time than any other mode re- quires. How desirable this celerity of ope- ration must often be, when venereal ulcera- tion is making great ravages in the palate, throat, &.c it is needless to insist upon. In patients, who have not strength to rub in ointment, and whose bowels will not bear the internal exhibition of mercury, the mode of fumigation may prove of great service. “ In the year 1776, the Chevalier Lalo- nette, a physician at Paris, laid before the public an account of a new mode of mercu- rial fumigation, free from the inconvenien- ces of former ones, and which in the space of thirty-five years, he had successfully em- ployed in more than four hundred cases, that had resisted all the ordinary methods of cure. His method consisted in enclosing the patient, previously undressed, in a kind of box resembling a sedan chair, with an opening at the top to let out the head, and another at the bottom, to which was fitted a small grate or furnace, having in it a heated iron for converting the mercurial remedy into fume. The preparation he made use of was a kind of calomel, which by repeated sublimation from iron filings, was so far de- prived of its muriatic acid, as to be in part reduced into running quicksilver ; and, while it possessed considerable volatility, was per- fectly'unirritating. Some of this powder, being strewed upon the hot iron placed be- low, was immediately converted into smoke, which surrounded the patient’s body, and after some time settled on his skin in the form of a white and very fine calx of quick silver : a complete dress, having its inner surface fumigated with the same powder, was then put on. — The remedy being thus generally applied to the mouths of the cu- taneous absorbents, soon got admission into the circulating fluids, and the constitution became thereby more speedily affected than by any other process known before.” {Aber- nethy's Surgical and Physiological Essays, Part 3.) As the fumigating powder used by M. La- lonette was very operose, and consequently a very expensive preparation, and appeared to have no advantage over one made by abstracting the muriatic acid from calomel Vor.. II 30 by means of ammonia. Mr. Abernethy has always employed the latter, which is pre- pared at the hospital in the following man- ner: Two drachms of liquor ammoniae are added to six ounces of distilled water, and four ounces of calomel are thrown into this liquor, and shaken up with it; the powder is afterward separated by a filter, and dried. The powder th is obtained is of a gray co- lour, and contains a good deal of quicksilver in its metallic state, which of course is ex- tremely volatile, but becomes oxydated when raised into fume, and afterward condensed into a white subtile powder. In local disease of the joints, such, for in- stance, as frequently takes place in the knee, and in sarcomatous enlargements of the breast in women, the late Mr. Sharp and Sir C. Blicke were accustomed to direct fumi- gated stockings, or under- waistcoats, to be worn ; by which these complaints were re- lieved, and the constitutions of the patients affected, without the trouble and unplea- santness arising from the use of the common mercurial ointment (See Abernethy's Sur- gical and Physiological Essays, Part 3.) Mr. Pearson procured Lalonette’s ma- chine, and made a considerable number of experiments to determine the comparative advantages of this method, and mercurial frictions. He found, that the gums became turgid and tender very quickly, and that the local appearances were sooner removed, than by the other modes of introducing mercury into the system ; but that it soon brought on debility, a rapid and premature salivation, and, of course, that the medicine could not be steadily continued. This - gen- tleman concludes, that where checking the progress of the disease suddenly is an object of great mo ment, where the body is covered! with venereal ulcers, or where the eruptions are large and numerous, so that there scarce- ly remains a surface large enough to absorb the ointment, the vapour of mercury will be advantageous. But he thinks it extreme- ly difficult thus to introduce a sufficient quantity of mercury into the system to se- cure the patient from a relapse, and there- fore the plan by no means eligible as a ge- neral practice. The vapour of mercury, he says, is singularly efficacious, when applied to venereal ulcers, fungi, and excrescences; but this plan requires an equal quantity of mercury to be given in other ways, as if the local application itself were not a mercurial one. ( Pearson on Lues Venerea , p. 145, fyc.) For the purpose of fumigating sores, the hydrargyri sulphuretum rubrum is common- ly used. Ulcers and excrescences about the pudendum and anus in women are said to be particularly benefited in this way ; and in these cases the fumes are most conveni- ently applied by placing a red-hot heater at the bottom of a night-stool pan, and after sprinkling on it a few grains of the red sul- phuretof quicksilver, placing the patient on the stool On other occasions, a small ap- paratus, sold at the shops, is used, which en- ables the surgeon to direct the fumes through a funnel against the ulcer in any situation MERCURY. Though mention has just been made of ve- degree of soreness of the gums, and (he vercat excrescences, L am of opinion with common specific effect of mercury in the Mr. Abernethy, that it is very questionable, animal system. But it will often fail of re- whether any are ever really of this nature, moving even a recent chancre ; and where [ know, that many excrescences and verru- the symptom has vanished during the ad- cae about the anus, and parts of generation, ministrations of corrosive sublimate, I have diminish and are cured by a course of mer- known a three month’s course of that medi- cury. This is the only argument in favour cine fail of securing the patient from a con- of their being venereal ; for. when tied, cut stitutional affection. The result of my ob- oif, or made to fall off by stimulating them servations is, that simple mercury, calomel with pulv. sabina*, and the subacetate of or calcined mercury, are preparations more copper, they are as effectually cured, as if to be confided in, for the cure of primary mercury had been given. In the military symptoms, than corrosive sublimate. The hospital at Cambray, I remember a man, on whose scrotum there were several warty ex- crescences of considerable size. Mr. Booty, assistant staff surgeon, prescribed mercury, by which they were certainly cured with surprising expedition In this particular case, I think the plan of treatment adopted was the best, because on account of the number of excrescences, and the situation of some of them at the lower and back part of the scrotum, it would have been difficult to have treated them altogether by local appli- cations. PREPARATIONS FOR INTERNAL EXHIBITION. The acetite of mercury is supposed to be a mild preparation, and was the active ingre- dient in the celebrated Keyser’s pills. In solution it has also been recommended to be applied externally for the removal of some cutaneous affections. It may be made into pills with crum of bread. The dose is from one to five grains every night. When it is wished to excite a salivation quickly, when mercurial ointment alone will not produce this effect, or cannot be em- ployed, and when fumigations are not con- venient nor agreeable, the hydrargyri oxy- dum rubrum is often prescribed. The com- mon dose is a grain, which may be increa- sed to two, a day. It is apt, however, to disagree with the stomachs and bowels of many patients; an inconvenience sometimes obviated by conjoining the preparation with opium. At present, the hydrargyrus cum creta is rarely or never prescribed for the cure of the venereal disease. But it is frequently prescribed as a mild alterative for children in doses of from gr. v. to gr. x. twice a day, blended with any viscid substance. The oxymuriate of mercury (corrosive sublimate) was a medicine highly praised for its antisyphilitic virtues by the celebrated Van Swieten, and, indeed, there is no doubt, that, like other preparations of mercury, it possesses such qualities. It retains great reputation, even now, and, probably, will always do so. However, like the red oxide, it sometimes deranges the stomach and bow- els, and from some surgeons does not receive the same degree of confidence, in respect to its power over syphilis, as mercurial frictions. Mr. Pearson remarks, that “ when the subli- mate is given to cure the primary symptoms of syphilis, it will sometimes succeed ; more especially when it produces a considerable latter will often check the progress of secon- dary symptoms very conveniently ; and I think it is peculiarly efficacious in relieving venereal pains, in healing ulcers of the throat, and in promoting the desquamation of eruptions. Yet, even in these cases, it never confers permanent benefit ; for, new symptoms will appear during t the use of it and, on many occasions, it will fail of afford- ing the least advantage to the patient, from first to last. I do sometimes, indeed, employ this preparation in venereal cases ; but it is either at the beginning of a mercurial course, to bring the constitution under the influence of mercury at an early period, or during a. course of inunction, with the intention of increasing the action of simple mercury. I sometimes, also, prescribe it after the con- clusion of a course of frictions, to support the mercurial influence in the habit, in or- der to guard against the danger of a relapse. But. on no occasion whatever do l think it safe to confide in this preparation singly and uncombined, for the cure of any truly vene real symptom.” ( Pearson on Lues Venerea.) The dose of oxymuriate is a quarter of a grain. The following is a common mode of or- dering it : f^. Hydrargyri oxmuriatis gr. 3 Aquae Nucis Moscbatae ^ij. Misce. ^ss. Omni nocte sumenda. The muriate of mercury (calomel) is not very much used by modern surgeons for the cure of the venereal disease. Sometimes, indeed, it is given in cases of gonorrhoea, both with the view of preserving the consti- tution from infection, and keeping the bow- els regular. It is more extensively given as an alterative, and for the cure of such surgi- cal diseases as require the system to be slightly under the influence of mercury. It generally proves actively purgative, when more than two or three grains are given. The most simple preparations of mercury have generally been deemed the most effec- tual in eradicating the venereal disease. The pilulae hydrargyri are the most simple of the internal formulae, being merely mercury triturated with mucilaginous or saccharine substances. Next to mercurial frictions, they are, perhaps, most frequently employed for the cure of the incipient form of the ve- nereal disease, that is, while a chancre is the only complaint. They are also very commonly given in all stages of the disease, to aid mercurial frictions in bringing the sys- tem under the influence of the specific remedy. Ten grains of the mass, kept for MOLLITIES OSSIUM. 235 these pills, is the usual dose. When they purge, opium will sometimes prevent this effect. See Venereal Disease. Mercury is employed both constitutional- ly and locally in numerous surgical cases ; for the removal of indolent thickenings and indurations o: parts ; for the relief of porri- go, herpetic diseases, tetanus, hydrophobia, hydrops articuli, iritis, and a multitude of other affections, which need not here be spe- cified. MEROCELE. (from yuego?, the thigh, and a tumour.) A femoral or crural hernia. See Hernia. MEZEREON was recommended by Dr. A. Russell for a particular class of venereal symptoms, in the following terms : “ The disease, for which I principally recommend the decoction of the mezereon root as a cure, is the venereal node that proceeds from a thickening of the membrane of the bones. In a thickening of the periosteum, from other causes, I have seen very good effects from it : and it is frequently of service in the removal of those nocturnal pains, with which venereal patients are afflicted ; though, in this last case, excepting with regard to the pain that is occasioned by the node, I own I have not found its effects so certain, as 1 at first thought I had reason to believe. I do not find it of service in the cure of any other symptom of the venereal disease. {Med. Obs. and Inq. Vol. 3, p. 194, 195.) Mr. Pear- son, however, asserts, unequivocally, that mezereon has not the power of curing the venerea] disease in any one stage, or under any one form, and if the decoction should ever reduce the venereal node, yet there will be a necessity for taking mercury in as large quantity, and for as long a time, as if no ^mezereon had been exhibited. Cullen found this medicine of use in some cutaneous af- fections, but, excepting an instance or two of lepra, Mr. Pearson has very seldom found it possessed of medicinal virtue, either in sy- philis, or the sequela? of that disease, scro- fula, or cutaneous affections. ( Pearson on Lues Venerea, p. 55, 59.) As the possibility of curing most forms of the venereal disease, not only without mer- cury, but without any internal medicines whatever, is now well established, it is diffi- cult to know what degree of importance to attach to observations, declaring certain ar- ticles of the materia medica efficient or inef- ficient in the cure of that disease ; because, if it admit of a spontaneous cure, but will not get well when mezereon, or any other parti- cular medicine is exhibited, we are necessa- rily-obliged to suppose, that such medicine is worse than useless. MODIOLUS. The crown or saw of a trepan. MOLLITIES OSSIUM. A morbid soft- ness of the bones, which become preterna- turally flexible, in consequence either of the inordinate absorption of the phospate of lime, from which their natural solidity is de- rived, or else of this matter not being duly secreted into their texture. The bones af- fected become specifically lighter. ( Sail - lant, Hist, de la Soc. Royale de Med. T. 8 .) Dr. Bostock made some experiments, with the view of ascertaining the proportion of earthy matter in bones affected with molli- fies : he examined a dorsal vertebra of a woman whose bones were found soft and flexible after her decease. In one part of the diseased bone, he found, that the quanti- ty of earthy matter only amounted to one- fifth of its weight, and in another, only to one-eighth, while the proportion in healthy bones amounted to more than one half of their whole weight. (See Med. Chir. Trans. Vol. 4, and Wilson on the Bones and Joints, p. 253.) In rickets, the bones yield and be- come distorted only by slow degrees, and retain their natural inflexibility ; but, in the present disease, they may be at once bent in any direction, and frequently admit of being readily divided with a knife. The mollifies ossium is an exceedingly uncommon disease, and its causes are buried in obscurity. It is supposed, however, to depend upon some peculiar state of the constitution, and the in- dividuals, attacked with it, have been re- marked to be mostly about, or rather be- yond, the middle period of life, {J. Wilson , Vol. cit. p. 252.) and generally, if not always, women. (Neumann in Abhandl. der K. K. Josephs Acad. 2 B. p. 173 ; Portal Cours d'Anatomie, T. 1, p. 15.) One instance, how- ever, is reported, in which the patient was a young man seventeen years of age. ( Thom - massin, in Journ. de Med. T. 43. p. 222.) Surgical writers have usually considered mollities and fragilitas ossium as two dis- tinct and different affections. Boyer thinks, however, that this point is by no means well established. He admits, that there have been a few rare instances of mollities, where the bones were completely flexible, without any degree of fragility. But, he contends, that in almost all the cases on record, the fragilitas and mollifies have been combined. He regrets that bones, affected wfith fragility, have never been chymically nor anatomi- cally examined, particularly as there have been persons who, while living, merely be- trayed the symptoms of mollities ossium, yet, in whom unsuspected fractures, evi- dently of long standing, were discovered after death ; while other fractures also hap- pened from the slightest causes during the examination of the same bodies. (See Boyer , Traite des Maladies Chir. T. 3, p. 607 — 609.) The truth of these observations is well illus- trated in the case lately reported by Mr. Wilson. (On the Bones, fyc. p. 254.) In the present place, I shall merely describe the pure mollities ossium, or that disorder of the bones, in which they become completely flexible, and lose all their natural firmness. And in order to give an idea of the disorder, I shall quote the case of Madame Supiot. In the year 1747 she had a fall which occa- sioned her to keep her bed for some time, and left great pain and weakness in her loins and lower extremities. In about a year and a half afterw r ard, she began to per- ceive her left leg particularly affected. Along with this weakness, she had violent MGLLIT1ES OSSIUM. Hid pains over her whole body, which increased after a miscarriage, and still more alter a natural delivery, in the year 1751. She was now seized with startings, great inquietude, and such violent heats, that she was almost continually in a sweat, and could not In-ar the least covering even in the coldest wea- ther, and while her pains continually increa- sed, she took notice that her urine precipi- tated a white sediment. Her pains abated on the appearance of the sediment, but she now observed that her limbs began to bend, and from this time the softness of them gra- dually increased till her death. In the month of April, 1752, the trunk of the body did not exceed 23 inches in length ; the thorax exceedingly ill formed, and the bones of the upper part very much distorted ; those of the lower part were very much bent, and the thigh bones became so pliable that her feet might easdy be laid on each side of her head. The right side did not, till after some time, become so deformed as the left; but it was surprising to observe the alterations which daily took place, and the different figures assumed by the limbs, in conse- quence of the increased softness .of the bones ; so that when the sediment in the urine was considerable, the disease of l he bones seemed to be at a stand, increasing considerably when it was suppressed. Be- sides this, she had violent pains, startings, difficulty of breathing, spitting of blood, and lastly, a fever, with convulsions. She d.ed in the beginning of November, 1752 and, on dissecting her body, the following ap- pearances were observed : 1 The muscles in general were of a very soft and pale con- sistence, the vastus externus, fascialis, qua driceps, biceps, and external parts of the gracilis, were much shorter than in their na- tural state, and more firm and tense ; while those on the opposite side were much elon- gated, thin, and very tender; in short, the whole muscular system had sulfered more or less, according to the action of the mus- cles in her Jifetime. 2. The bones were entirely dissolved, the periosteum remaining unhurt, so that they exhibited only the form of a cylinder. 3. The heart and large blood- vessels, both veins and arteries, contained large black polypi, of a viscid consistence, and very unlike those usually found in dead bodies. A case of softness of the bones is related by Mr. Gooch, but considerably different from the above, as it was attended with a remarkable fragility of them before they became soft. It likewise began with pains through the whole body, attended with fe- verish symptoms ; but after some weeks, these pains were confined chiefly to the legs and thighs, and they were not increased by pressure. This fragility of the bones does not appear to have been the case u ith Ma- dame Supiot. In the month of June, 17-19, ]Vlr. Gooch’s patient broke her leg in walk- ing from her bed to a chair, and heard the bone snap. No callus, however, formed, though the fracture was instantly reduced, and treated by one of the best surgeons iu her part of the country ; but instead of this, the bones began to grow flexible, and in a few months, were so from the knee to the ankle. The disease still continued to in crease, so that, in a short time, the other leg and thigh were atfected in the same maimer, after which both legs became cede matous, liable to excoriations, and to dis- charge a thin yellow ichor. Scorbutic symptoms began to appear in the winter after the leg was broken, and her gums be- gan to bleed. Tonic medicines were exhi- bited without any success, except that her menstruation became more regular, and her appetite and digestion better than before ; but towards the end of her life, her breathing became difficult, the spine distorted, and a pain in the loins took place upon every motion of the vertebra; : and as her limbs were now quite useless, she was obliged to sit upright in bed. At last, trie ends of the bones on which she sat, having become also very soft, spread much, and the ends of her lingers and thumbs, by frequent endea- vours to raise herself, became also very broad and the phalanges crooked. The flexibility of the bones gradually increased, and became more general, attended with a wasting of the flesh, and excessive difficulty of breathing. Hie menstrual flux totally- ceased four months before her death ; her legs, which were anasarcous, and excoriated almost all over, became erysipelatous; but she retained her senses to the last. She ex- pired suddeidy, having talked in a composed manner concerning her miserable situation and approaching end only a few moment* before. On examining the body, she was found to have lost two feet two inches of her na- tural stature. The heart and lungs appear-* ed sound, but had been much confined, principally by the liver, which was enlar- ged in an extraordinary degree ; it was not, however, scirrhous, nor in any other way- diseased. The spleen was very small, and the mesentery had one large scirrhous gland. All the bones, except the teeth, were softened, so that scarcely any of them could resist the knife ; but those of the lower extremities were the most dissolved, being changed into a kind of parenchymous substance, like s >ft dark-coloured liver, without any offensive smell. So complete- ly, indeed, were they decomposed, that the knife met with less resistance in efttting through them than in sound muscular flesh, though some bony lamella; were here and there to be met with, but as thin as an egg- shell. The most compact bones, and those which contained the greatest quantity of marrow, were the most dissolved; and it was observable, that the dissolution began internally, for the bony lamina; remained here and there on the outside, and nowhere else. The periosteum was rather thicker than ordinary, and the cartilages thinner ; bul not in a state of dissolution. The bones were found to contain a great quantity of oily matter and little earth. No cause could be assigned for the disease ; and in the ease MORTIFICATION 237 of Madame Supiet, the one assigned, viz. that of her eating too much salt, seems to- tally inadequate to explain the origin of the disorder. All the cases of mollities ossium on record have proved fatal, and no means of cure are yet known. For additional observations, connected with this subject, reter to tragilitas Ossium and Rickets. Royer and Kicherand treat ot the mollities ossium, and rickets, as one and the same disease. Rut, as Mr. Wilson ob- serves, the first difters trom rickets, in at- tacking people of middle age, or rather older, and not particularly children ; and it differs also in the change produced in the bones themselves, which, when dried, do not appear as if they had been long steeped in weak acid, with their animal part nearly unchanged ; but both the phospnat ot Ihne and the animal matter appeal to have been absorbed, so as to leave mere shells, which are also softer than natural bone of the same thickness. Mr. Wilson further inform's us, that large cavities are met with in the substance of tbe bones, and sometimes com- municate with the soft parts surrounding them. In some of these c..viiies is contain- ed oily matter, like boiled marrow ; and in others, masses of coagulated blood, and a soft inorganic substance. ( J . Wilson on the Bones , ty-c. p. 253. Acrel, Diss. Descriplion- em et Casus aliquot Osteomalacia: sistens; Up- sal, 1788. Morandin Joura.des Savans, 1792, et M6m. de VAcad des Sciences , i 752. Morand , junr. in Mem. de l' Acad, des Sciences , 1764, p. 206. See also T. Lambert , Relation de la Matadie de Bernard d'Armagnac, sur un Ramollissement des Os ; Toulouse, 170o. Fer- nelius , in lib. de abditis rerum causis. Th. Bartholinus, Hist. Auat. Cent. 4. P til , Histoire d6 l' Acad, des Sciences, 1722. Horn, ibid. 1764. Gagliardie, Anatomes Ossium, Romes , 1789. C. G Ludwig, Pro^ratnma, quo observata in sectione Cudaveris Fcemina cujus ossa emollita erant proponit ; Lips 1757. Fries, Dissert.de Emolliti one Jssium, Argent- tor. 1775. Thompson m Med. Ob e cations and Inquiries. Vol. 5. p. 259. Chirurgiccu Ob- servations and Cases, by Wiilium Bromjield, Vol. 2, p. 50, 4-’C. Boyer, i r ait e des Maladies Chir. T. 3, p. 607, s,c. Pa is, lb 14. tiiche- rand, JYosogr. Chir. T. •>. p 14 2. What these two writers say , however, chiefly relates to rickets. We meet with casi s of Mollities Ossium in the Philosophical Transactions ; Act. Haffniens ; Ephem.JVat. Cur. ; Sudani's Obs Chir. ; the writings of Foresius ; Gooch's Chirurgical Works, Vol. 2 ,p. 593 — 399. Ed. 1792, ty-c. James W.san Lectures on the Structure and Bhysiology of the Paris com- posing the Skeleton ; and on the Diseuses of the Bones and Joints, p. 252, <£-c. 8co. Load. 1820 .) MONOCULUS. (from ptova?, single, and oculus, the eye.) A bandage formerly ap- plied to the fistula lacbrymalis, and diseases of the eye. It consists of a single-headed roller three ells iong^ In order to apply it to the right eye, it is to be held in the hand, and its end in the left? et vice versa. This end is to be put on the back of the neck, and one turn of the roller is to be carried round, over the forehead, so as to meet the ex- tremity of the bandage. The roller is then to descend under the ear of the side affected, and to pass obliquely over the cheek under- neath the eye, and next over the root of the nose, and opposite the parietal bone, to the nape of the neck. The third turn of the roller is to overlap the second a little : the third the fourth ; making what the French call doloires ; and the application of the ban- dage is completed by making turns round the head, l he use of the monoculus was only to retain dressings. ( Encyclopedic Mcthodique ; Partie Chir.) MORTIFICATION is of two kinds; the one, without inflammation; the other, pre- ceded by it. To this last species of mortifi- cation, the terms inflammatory, humid, or acute gangrene, are often applied, while the second, or that which is not preceded by any or much inflammation, has been distinguished by the epithets, dry or chronic, and sometimes idiopathic, when no cause for the origin of the disease can be assigued. According to Mr. Hunter, inflammation is an increased action of that power, which a part naturally possesses ; and in healthy in- flammations, at least, ii is probably attended with an increase of power. In cases, how- ever, which are to terminate in mortifica- tion, there is no increase of power ; but, on the contrary, a diminution of it. This, when joined to an increased action, becomes a cause of mortification, by destroying the balance, which ought to subsist between the power and action of evt-ry part, i here are, besides, cases of mortification, preceded by inflammation, which do not arise holly from that, as a cause : of this kind, are the carbuncle and the slough formed in the small-pox pustule. (Hunter.) The first general division of mortification, therefore, is into two kinds; first, into the inflammatory, humid , or acute; and secondly, into the dry, or chronic. Rut the disorder is also subdivided into many species, which are determined by the nature of tneir particular exciting causes, as will be present- ly detailed. However, it is remarked, that acute, or rapid mortifications, are not necessarily hu- mid, as the slougu from the application kali purum proves, and the c onverse also is true in some cases of sphacelus senilis ( James on Inflammation, p. 96.) Another modern writer also asserts, tnat mortification from wounds and external injuries may be either humid, or dry* or of both kinds together, where tlie circumstances are particular. (Guthrie on Gunshot Wounds , fyc.p. 122, Ed. 2.) The doctrine also that any case of mortification is entirely without inflamma- tion, has sometimes been deemed question- able ; and Mr. James expresses bis belief that the disorder is generally preceded by inflammation, and invariably accompanied with some degree of it. And, says he., “ w hether mortification be a consequence of MORTIFICATION. 238 inflammation, or not, it may, perhaps, with reason be considered, as standing in the same relation to inflammation, as adhesion, suppuration, or ulceration : they may all be preceded by a high degree, or it may be scarcely sensible.” (P. 84, 85,) When any part of the body loses all mo tion, sensibility, and natural heat, and be- comes of a brown, livid, or black colour, it is said to be atfected with sphacelus , that is, complete mortification. As long as any sensibility, motion, and warmth, continue, the state of the disorder is termed gangrene This word is here made use of to signify only a degree of sphacelus, or rather the process, by which any local disorder falls into the state of complete mortification. Many authors use both terms synonymously ; but it is to be observed, that gangrene does not invariably end in sphacelus ; nor is the latter always preceded by the former. ( Richler , Anfangsgr. der IVundarzn. B. 1, Kap. 3.) There are some surgical writers, who make the distinguishing circumstance of sphacelus to be the extension of the disor- der to the bones as well as the soft parts. ( Lassus . Pathologie Chir. T. 1 , p. 30, Ed. 1809.) At present, however, this last application of the term sphacelus is never made ; for, as Mr. Pearson has rightly observed, the dis- tinctions, “ which are founded merely upon the parts, that suffer, or upon the profundity, to which the disease has penetrated, seem inadequate and useless.” ( Principles of Surgery , p. 115, Ed. 2) The manner, in which Dr. J. Thomson views the subject, may be considered as coinciding with the general sentiments of the best modern sur- geons. “ I shall employ the term gangrene, (says he) to express that state of mortifica- tion, in inflamed parts, which precedes the death of the part ; a stage, in which there is a diminution, but not a total destruction of the powers of life ; in which the blood ap- pears to circulate through the larger vessels ; in which the nerves retain a portion of their sensibility ; and in which, perhaps, the part affected may still be supposed to be capable of recovery. The word sphacelus, I shall use to denote the complete death, or mor- tification of a part ; that state, in which the powers of life have become extinct ; in which the blood ceases to circulate ; and in which the sensibility of the nerves is lost, whether the dead, or mortified part has, or has not, become actually putrid, or shown any ten- dency to separate and fall away from the living and sound parts. Putrefaction or the spontaneous process, by which animal ho lies are decomposed, is an accidental, and not a necessary effect of the state of mortification. It takes place at very different periods, after the death of particular parts ; and these periods, it may be remarked, are always regulated, not only by external circumstan- ces, such as the humidity and temperature of the atmosphere, but, also, by the peculiar structure and morbid conditions of the ani- mal texture, or organ, in which the putre- faction occurs. The term sphacelus, has, 1 know, been employed to express, that a part is not only completely dead, or mortified, but, also, that that part has become putrid, and is in a state of separation from the sur- rounding and living parts. But, as putrefac- tion is not a necessary, or immediate conse- quence of mortification, or partial death in animal bodies, this use of the term sphacelus is obviously improper.” (See Thomson’s Lectures on Inflammation, p. 504 ) The causes of mortification are either internal, or external. It is commonly taught in the medical schools on the continent, that the internal ca ises probably operate after the rna oner of a deleterious substance, vhich being introduced into the circulation, occasions a putrefaction of the fluids. ( Lassus , op. et loc. cit.) — Boyer also professes a simi- lar notion, (See Trnite des Maladies Chir. T. 1, p. 140.) as well as Larrey in his account of traumatic gangrene ; a statement, which has drawn forth the criticisms of Mr. Gu- thrie. The doctrine is supported by no sort of proof, and may be considered as entirely hypothetical, if not decidedly erroneous. There .are, indeed, as Boyer has noticed, some spontaneous mortifications, the primi- tive cause of which is not always well un- derstood : an inflammation, apparently slight, may become gangrenous immediately it has made its appearance. In scorbutic, venere- al, and small-pox cases, we have daily in- stances of this fact Other internal causes, without any very evident pre-existing dis- ease, sometimes destroy persons, bv gan- grenous mischief, who are but little advanced in years. ( Saviard . Obs. 16. Haller , Disput. Chir. T.4,/7.551.) Certain poisonous, acrid, caustic substances taken inwardly, or intro- duced under the skin, may have the same effect, by annihilating the vital action, or destroying the texture of the paris. ( Lassus , Pathologie Chir T. 1 , p. 31.) But, though these observations may all be entirely cor- rect, they by no means justify the conclusion, that the internal causes of mortification ever act like a deleterions matter producing a putrefaction of the fluids. The mortification of the toes and feet so well described by Mr. Fott, is supposed to proceed chiefly from unknown internal causes, though sometimes attended with an ossified state of the arte- ries. Another remarkable specimen of mortifi- cation from an internal cause, is that origin- ating from eating bread made of bad black wheat, or rye. Besides occurring as an original idiopathic disease, and from obstruc- tion of arteries, chronic, or dry gangrene (observes Dr. Thomson) may be induced by the action of substances taken into the stomach, which seem to produce it as a spe- cific effect in parts remote from the source of the circulation. The most singular ex- ample, which we have of this, is in the gan- grene produced by the eating of a particular kind of unsound or diseased rye. This species of mortification has been rarely- observed in England ; but it lias been fre- quently seen on the continent, where it ha s been repeatedly known to prevail in som MORTIFICATION. 239 districts, where rye forms a principal article alone. In others, Noel was obliged to have of food, as an endernial disease. It occurs, however, in such districts only after wet seasons, in which that grain is affected with a particular disease, well known in France by the name of the Ergot , or cockspur rye. In this disease, the grains of rye grow to a large size, acquire a black colour, and have a compact horny consistence. The species of mortification, produced hy eating this substance, was first particularly described by Dodard. (See Journ. des Savans, an. 1676.) The part affected became at first insensible and cold, and, in the progress of the disorder, dry, hard, and withered. In very malignant cases, there was delirium. Dodard’s description of the complaint was very imperfect ; but he has mentioned a circumstance, tending strongly to prove, that the disease actually arose from the alleged cause ; viz. that fowls, fed with cock- spur rye, are killed by it. Saviard informs us, that he saw this disease in the year 1694, at the Hotel Dieu of Orleans It attacked the upper and lower extremities, which were rendered, in the course of the disorder, as dry as touch-wood, and as emaciated as Egyptian mummies. In 1710, Noel, sur- geon to the Hotel Dieu at Orleans, transmit- ted to the Royal Academy of Sciences at Paris an account of this peculiar mortifica- tion. About fifty people, men and children, had come that season into his hospital, with the affliction. According to Noel, the disor- der always began in the toes, and extended itself gradually along the foot and leg, till it sometimes rose to the upper part of the thigh. He had never seen any of the female sex affected with it, and had observed only one instance of it in the upper extremities. The Academy received the history of one case, in which the lower extremities were separated from the body in the articulations of the thigh-bones with the acetabula ; the first example, (Dr. Thomson believes) of this separation upon record ; and it was the oc- currence of this, and of similar cases, that probably first suggested the operation of am- putation at the hip-joint. (See Thomsons Lectures on Inflammation, p. 54E) As Noel’s patients did not come under his care, till after the disease had existed some time, he could not describe from his own observation the early symptoms ; but the patients had often told him, that the disease generally began in one, or both feet, with pain, red- ness, and a sensation of heat, as burning as the fire ; and that, at the end of some days, these symptoms ceased, as quickly as they had come on, when the extreme sensation of heat, which they had formerly felt, was changed into cold. The part affected (adds Noel) was black, like a piece of charcoal, and as dry as if it had passed through the fire. After some time, a line of separation was formed between the dead and living parts, like that which appears in the separa- tion of a slough produced by the cautery ; and the complete separation of the limb was, in many cases, affected by nature recourse to amputation. This disease appeared in Switzerland in 1709 and 1716, and its symptoms and pro- gress in that country have been accurately described by Langius in a dissertation, enti- tled, “ Descriplio Morborum ex esu Clavo- rum Secalinorum." Gassaud, physician in Dauphiny, where this disease appeared also in 1709, states, that many of the patients were affected with swellings of the feet and legs, and of the hands and arms, which degenerated into a gangrene, that penetrated to the bone, and produced a separation of the affected limb. The disorder w r as attended with different symptoms in different individuals. Some suffered very violent pain, accompanied by an insufferable sensation of heat, although the part affected often felt cold to the touch. In other patients redness, with much swell- ing, supervened, attended with fever and delirium. Other patients were without any fever, or delirium, though they seemed to suffer equal pain In some patients, the parts affected became withered, dry, and black, like charcoal. The separation of the dead parts from the living took place with the most excruciating pain, and a sen- sation resembling that produced by the di- rect application of fire. This sensation was sometimes intermittent ; and, in other in- stances, it was succeeded by an equally harassing sensation of cold. According to Bossau, surgeon to the hos- pital of St. Antoine, in Dauphiny, the cases, which he saw, were not all of the dry kind, the limb sometimes becoming putrid, and maggots being generated. He says that the disease was not infectious, and it attacked indiscriminately men, women, and chil- dren. The degree of fatality caused by this spe- cies of mortification seems to have been extremely various. In the Memoirs of the Royal Academy of Sciences for 1748, M, Duhamel mentions, that of 120 persons afflicted, scarcely four or five recovered with their lives. According to Langius, it was equally fatal in Switzerland. Dr. Thomson believes, that the preceding sort of gangrene has never occurred in this country, excepting, perhaps, the cases re- corded by Dr. Charlton Woolaston, in the Phil. Trans, for 1762; and which proceeded from eating unsound wheat, not rye. (See Lectures on Inflammation, p. 548.) For fur- ther particulars relating to this curious kind of mortification, I must refer the reader to this valuable work. The external causes of mortification, which are manifest, and act mechanically or chymically, are burns; excessive , cold ; the application of caustics ; the presence of any' ichorous, urinary, or fecal matter effused in the cellular substance ; violent contusions, such as are produced by gunshot wounds, or bad fractures ; the strangulation of a part, as in cases of hernia, or when polypi, or other tumours are tied ; a high degree of in- MORTIFICATION. 240 fl animation; and, lastly, everything, that has the power of stopping the circulation and nervous energy in parts. ( Lassus , Pa- thologic Chir. T. 1, p. 34, 35.) Inflammation is one of ihe most frequent occasional causes of mortification. But, as we have already remarked, the death of a part may take place without any well-mark ed appearance of previous inflammatory disorder ; and the latter even when present has frequently less share in the mischief, than other incidental circumstances, and is in reality, only an effect of the very same cause, which produces the sphacelus itself, ft is oftentimes a matter of doubt, whether actual inflammation precedes the occur- rence or not ; for a part, before it mortifies, Is in certain instances only affected with pain, and with no degree of preternatural redness. Lastly, when mortification is, un- questionably, preceded by inflammation, there are so many varieties of the disorder depending on incidental causes, that these latter demand more attention than the inflam- mation. (Richter, .inf angsgr B 1 Kap. 3.) Mr. James enumerates the following cir- cumstances, as capable of influencing, in a very great degree, the disposition of inflam- mation to terminate in mortification. 1. The powers of the part, in which the in- flammation occurs, being naturally weak, as in fibrous membranes, the scrotum, &.c. 2. The remote supply of blood, or nervous energy, as in the lower extremities. 3. Ob- struction to the return of blood. 4. To the supply of blood. 5. Disease in the heart or vessels. 6. Debility from age, habits of life, disorder of the digestive organs, or fever. 7. Poor living, foul air, improper food, scur- vy, &c. 8. Impairment of organization from external injury, 0. Of the nervous power by poisons. 10 Undue excitement of weakened parts. 11. Depressing reme- dies. 12. Pressure and tension. 13. Ex- cessive violence of inflammatory action. 34. Peculiar disposition in the constitution. (James on Inflammation, p. lo2.) Healthy phlegmonous inflammation sel- dom ends in mortification, except when it is unusually violent and extensive. Of all the inflammatory complaints, to which the system is liable, erysipelas is ob- served most frequently to terminate in gan- grene ; and whenever phlegmon is, in any degree, conjoined with an erysipelatous af- fection, which it not unfrequently is, it seems thereby to acquire the same tendency, being more difficult to bring to resolution or sup- puration than the true phlegmon, and more apt to run into a mortified state. The symptoms of mortification from in- flammation take place variously, yet gene- rally as follows: — The pain and sympathetic fever suddenly diminish, the part affected becomes soft, and of a livid colour, losing, at the same time, more or less of its natural warmth and sensibility In some places, the cuticle is detached ; while, in other situa- tions, vesicles arise, filled with a clear, or turbid fluid. Such is the state, to which we apply the term gangrene, and which stage of the disorder too often rapidly advances to sphacelus, when the part becomes a cold, black, fibrous, senseless substance, called in technical language, a slough. It merits notice, however, that, “ in cases, in which gangrene immediately succeeds to inflammation, these two morbid states may, in some measure, be regarded as stages, or periods, of the same disease. They pass in- sensibly info one another; nor is it possible to say precisely where the one state ends, and the other commences. The symptoms of inflammation, in these cases, do not dis- appear before those of gangrene come on ; but seem rather to undergo a gradual and almost imperceptible change, or conversion, into one another. The redness acquires a deeper tin^e, and spreads further, than for- merly ; the swelling increases and becomes more doughy; and, in this incipient stage, the gangrene, particularly when it attacks the cuta eous texture, often bears a consi- derable resemblance to erysipelas.” (Sfee Thomson's Lectures on Inflammation, p. 506.) It is to be observed, also, that u the part of the body which becomes affected with gangrene, does not immediately lose its sensi- bility ; for the pain, on the contrary, is often very much aggravated by the approach of this state. I'he blood also still continues to circulate, at least in the larger vessels of the part, but, perhaps, with less force : and from the resistance which it meets with in passing through the capillaries, in less quantity, than formerly. The serous effusion into the cel- lular membrane continuing to increase, and the action of the absorbent and sanguiferous vessels to diminish, the part becomes at length incapable of being restored to its former office in the animal economy. It is, therefore, in its earlier stages only, that gangrene is to be considered as an affection admitting of cure ; for there are limits, be- yond which, if it pass, recovery becomes impossible. These limits it may not, in every instance, be easy to define . but they form the boundaries between incipient gangrene and the ultimate termination of that state in sphacelus.” (Thomson, op. cit. p. 507.) • The causes which produce mortification by impeding the return of blood from the part affected, for the most part operate by making pressure on the trunk or principal branches of a vein. In these instances, there is always an accumubition of blood in the part which first swells, becomes of a livid colour, tense, and very painful. Soon afterward, blisters arise and the part be- comes soft, oedematous, cold, insensible, emphysematous, black, and fetid. Such are the circumstances which happen in strangu- lated hernia, in tied polypi, and in a limb in which the veins have been so compressed by any hard swelling, such as the*liead of a dislocated bone, as to excite mortification. Other causes operate by preventing the entrance of arterial blood. The application of a ligature to an artery, as practised in several surgical cases, and all external pressure, that, closes the artery, or arteries- MORTIFICATION 241 on which a pari entirely depends for its siipply of blood, have this effect. Mortifica- tion does not, however, always take place when the trunk of an artery is rendered im- pervious, because nature furnishes the ne- cessary supply of blood through collateral ramifications. But when the disorder does happen, the part commonly first becomes pale, ffaccid, and cold, and soon afterward shrinks, loses its sensibility, grows black, and perishes. It is usually represented by writers, that mortification may proceed from a mere less- ening of the communication of blood and nervous energy to a part. However, it is to be observed, that parts, deprived of all connexion with the sensorium, by the divi- sion or paralytic state of their nerves, do not frequently perish on this account. But as their functions are carried on with less vi- gour, and their vitality is weakened, the same causes which sometimes produce mor- tification iu parts differently circumstanced, must much more readily occasion it in them. Among the causes of the present species of mortification, maybe mentioned great universal debility ; extreme old age ; a thickening and ossification of the coats of the arteries, and a consequent diminution of their capacity, and of their muscular and elastic power. Cowper, the anatomist, was one of the earliest writers who took notice of this ossi- fication of the arteries of the leg, in persons who had died of mortification of the feet and toes. (See Phil. Trans. Vol 23, p. 1195, and Vol. 24, p. 1970.) A similar case was remarked by Mr. Becket, of which he has given an account in his Chirurgical Obser- vations. The occurrence was also men- tioned by Naish. (See Philosoph. Trans. Vol. 31, p. 226.) Dr. J. Thomson has seen one example of a very complete ossification of the arteries of the leg, accompanying a mortification of the feet and toes. (0?i Inflammation, p. 537.) SpeaKing of the same subject, Mr. Hodgson remarks : 11 Ex- perience has proved this condition of the arteries to be at/least a constant attendant upon one species of gangrene, to which the extremities of old subjects are liable ; and I have found the three principal arteries of the leg nearly obliterated by calcareous matter in two fatal cases of this disease. But our knowledge of the power of collate- ral circulation, in every part of the body, will not allow us to admit the obliteration of the trunks as a sufficient cause of mortifi- cation, from a deficient supply of blood. It is therefore necessary for us to remember, that the same disease may probably exist in the collateral branches, upon which it has produced similar effects. But if an extent of vessel be converted into a calcareous cy- linder, it loses its elasticity and organic pow- ers, so as to be unable to afford any assist- ance to the propulsion of the blood ; and the existence of parts, supplied by vessels in this state, constitutes a strong argument against the agency of the arteries in the cir- culation of the blood- The above observa- Vol, II 31 tions, on the cause of this species of gan- grene, at once expose its incurable nature ; and this stale of the blood-vessels renders the danger of amputation very considerable, unless fortunately the disease in the arteries does not extend to the part at which the ligature is applied.” (See Hodgson’s Trea- tise on the Diseases of the Arteries and Veins , p. 41.) However, although the ossified state of an artery must certainly be unfa- vourable to its healing, it does not con- stantly prevent this desirable event. (See Case in Medico- Chir. Trans. Vol. 6, p. 193.) The preceding facts are particularly enti- tled to attention, because, as we shall pre- sently find, the opinion that the mortification of the toes and feet arose from an ossifica- tion of the arteries, was considered by Mr. Pott as destitute of foundation. It is probable, however, that sometimes other causes are concerned. Fabrieius Hil- danus mentions a fatal case of mortification of the feet and legs, where the patient was in the vigour of life, and apparently of good constitution. After death, a scirrhous tu- mour was found surrounding and compress- ing the inferior vena cava, and aorta, near their bifurcation, so as to prevent the free circulation of the blood in the lower extre- mities. Mortification of the extremities also sometimes occurs from deficient circulation, in the progress of diseases of the heart. The mortification, arising from long con tinuance in the same posture, is chiefly attri- butable to the unremitted pressure which parts sustain, and which obstructs the cir- culation Surgeons have frequent occasion to see melancholy examples of this kind of mortification, particularly in cases of frac- tures, paralysis from disease of the vertebrae, &x. The mischief most readily occurs where the bones have the least flesh upon them, and, consequently, where all external pressure has the greatest effect ; as, for instance, about the os sacrum, os ilium, •spines of the scapula, &c. The disordered part always first becomes soft, livid, red at the circumference, and cedematous, after- ward losing its sensibility, and acquiring a, black appearance : at length it is converted into a foul sloughing ulcer. Though long continuance in the same posture is the grand cause of this kind of mortification, yet incidental circumstances are frequently combined with it, and have great influence ever the disorder. These are, great debility, the same state of the system as exists in typhus fever, impure air, unclean bedding, &c. There are some causes which produce death in a part at once, by the violence of their operation. A very powerful blow on any portion of the body may destroy the vitality of the fibres and vessels in this sud- den manner. Lightning, strong concentra- ted acids, and gunshot violence, sometimes act in a similar way. When a bail enters the substance of parts with great force and rapidity, many of the fibres, which are in its track, are frequently "killed at once, and must be thrown off’ in the form of sloughs, MORTIFICATION, 242 before the wound can granulate and heal. (See Hunter on Gunshot Wounds.) Cold is often another 'cause of mortifica- tion, and when parts which have been fro- zen, or frostbitten, are suddenly warmed, they are particularly apt to slough. I find in Baron Larrey’s valuable publica- tion, some interesting observations on the gangrene from cold. He acquaints us, that after the battle of Eylau, one of the most grievous events to which the French sol- diers were exposed, was the freezing of their feet, toes, noses, and ears: few of the van- guard escaped the affliction. In some, the mortification was confined to the surface of the integuments of the toes or heels ; in some, the skin mortified more deeply, and to a greater or lesser extent; 'while, in otters, the whole of the toes, or foot, was destroyed (See Programma quo frigoris acrioris in corpore humano effectus expendit. Haller , Disp. ad Morh . Lips. 1755.) “ All the writers, on this species of morti- fication (says Larrey) have considered cold as the determining cause; but, if we attend to the period when the complaint begins its progress, and the phenomena which accom- pany it, we shall be convinced, that cold is merely the predisposing cause. In fact, during the three or. four exceedingly cold days which preceded the battle of Eylau, (the mercury having then fallen to 10, 11, 12, 13, 14, and 15 degrees below zero of Reaumur’s thermometer) and until the se- cond day after the battle, not a soldier com- plained of any symptom depending upon the freezing of parts. Nevertheless, they had passed these days, and a great portion of the nights of the 5 th, 6th, 7th, 8th, and 9th of Feb. in the snow, and the most severe frost. The imperial guard especially had remained upon watch in the snow, hardly moving at all for more than four and twenty hours, yet no soldier presented himself at the am- bulance,* nor did any one complain of his feet being frozen. In the night of the 9th, and 10th of February, the temperature sud- denly rose, the mercury ascending to 3, 4, and 5 degrees above zero. A great quantity of sleet, that fell on the morning ofThe 10th, was the forerunner of the thaw whhj^took place in the course of that day, and continu- ed in the same degree for several days. From this moment, many soldiers of the guards and the line applied for succour, complaining of acute pain in the feet, and of numbness, heaviness, and prickings in- the extremities. The parts were scarcely swol- len, and of an obscure red colour. In some cases, a slight redness was perceptible about the base of the toes, and on the back of the foot. In others, the toes were destitute of motion, sensibility, and warmth, being alrea- dy black, and, as it were, dried. All the * The ambulances of the French army are caravans, furnished with an adequate number of surgeons, and every requsite for the dressing of w ounds, and the im- mediate performance of operations, upon which last circumstance, in particular, the life of the wounded soldier often depends. These caravans follow the most rapid movements of the army, and are always capable of beeping- up with the vanguard. patients assured me, that they had not expe- rienced any painful sensation during the severe cold to which they had been exposed on the night-watches of the 5th, 6th, 7th, 8th, and 9th of February, and that it was not till the night of the 10th, when the tem- perature had risen from IS to 20 degrees, that they felt the first effects of the cold.” It is further noticed by Larrey, that such pa- tients as had opportunities of warming them- selves in the town, or at the fires of the night-watches, suffered in the greatest de- gree. (See Larrey' s Memoires de Chirurgis Militaire, T. 3, p. 60 — 62.) Sometimes mortification seems to depend either upon the operation of some infectious principle, or, at all events, upon causes which simultaneously affect numerous indi- viduals; for instances have been known, in x which almost all the ulcers and wounds in large hospitals became nearly at the same time affected with gangrenous mischief. (See Hospital Gangrene.) Mortification is very frequently occasion- ed by the injury which parts sustain from the application of fire and heated substances to them. When the heat is very great, the substance of the body is even decomposed, and of course killed at once. On other oc- casions, when the heat has not been so vio- lent, nor sufficiently long applied, inflamma- tory symptoms precede the sloughing. Cutaneous texture is that in which, we have the best opportunity of observing the phenomena and progress of gangrene. When it occurs as a consequence of inflamma- tion, the colour of the skin changes from the florid red to a darker shade ; and in the progress of the disease it acquires a livid hue. The cuticle often separates at certain points from the skin, and the vesications, termed phlyctenee, are formed, which usu- ally contain a bloody-coloured serum. As sphacelus comes on, the livid hue disap- pears, and a slough is formed, which is sometimes ash-coloured ; sometimes black. It is not always easy to judge of the extent of mortification from the appearance of the skin ; for, when the subjacent cellular membrane is affected, the disorder may occupy a greater extent internally, than upon the surface. In a spreading gangrene, the red colour of the affected skin is insensibly lost in the sur- rounding integuments ; but, when gangrene, followed by sphacelus stops, a red line, of a colour more lively than that of gangrene, is generally perceptible between the dead and living parts. It is at the inner edge of this inflamed line, where we usually see the ulcerating process begin, by which the se paration of the dead from the living parts is affected. (See Thomson's Lectures on Inflam- mation , p. 511, 512.) Mortification occurs frequently in cellular texture. The skin which covers dead cellu- lar substance, generally has a gangrenous ap - pearance, and afterward either ulcerates, or sloughs. In some coses, the portion of spha- celated cellular texture is small, as in the ma Jignant boil ; in others, extensive, as in case* MORTIFICATION ot carbuncle. In erysipelas phlegmonoides, the cellular membrane, connecting together the muscles, tendons, nerves, blood-vessels, &e. often perishes to a great extent. Here large portions of skin are frequently also destroyed by sloughing, or ulceration, so that Smuscle, blood-vessel, tendon, nerve, &c. are exposed to view, quite denuded of their proper coverings, and in different states of disease. Artery is the texture, endowed with the greatest power of resisting its own destruc- tion by mortification. “ 1 have (says Dr. Thomson) in various instances of erysipe- las phlegmonoides, seen several inches of the femoral artery laid completely bare by the gangrene, ulceration, and sphacelus of the parts covering it, without its giving way before death. The arteries in these, and other similar instances, in which 1 have seen them laid bare in the neck and arm, by ab- scess terminating in fortification , had the appearance of raw flesh, and were obviously thicker and more vascular than natural. The blood circulated through them, and assisted in supplying with nourishment the parts upon which they were distributed.” (P. 513.) I have often seen tbe truth of the foregoing statement sadly illustrated in cases of slough- ing buboes, by which several inches of the femoral artery were exposed. I have seen the throbbing brachial artery denuded for more than a month, nearly its whole extent along the inside of the arm, by the ravages of malignant and pseudo-syphilic ulceration, attended with repeated sloughing ; and yet hemorrhage had no share in carrying off the unfortunate patient. ft is a curious fact, that the blood coagulates in the large arteries, which lead to a morti- fied part. This occurrence takes place for some distance from the slough, and is the reason why the separation of a mortified limb is seldom followed by hemorrhage. The same occurrence also affords an ex- planation, why, in the amputation of a mor- tified limb, there is sometimes no hemorrhage from the vessels, although the incisions are made in the living part. This fact was first particularly pointed out by Petit, the sur- geon. (See Mim. de VAcad. des Sciences, 1732.) “ When a gangrened limb (says (his celebrated surgeon) is cut off in (be dead 'part, no hemorrhage occurs, because the blood is coagulated a great way in the ves- sels.” He adds, l£ We have several exam- ples of limbs amputated, on account of gan- grene, in which no hemorrhage occurred, although the amputation was made a consi- derable way in the living parts ; because the clot was not confined in these cases to the dead part, but was continued forwards into the living as far as the inflammatory dispo- sition extended.” According to Dr. Thomson, cases, in con- firmation of the foregoing statement, are recorded by other practical writers, espe- cially Quesnay, and Mr. O’Halloran. Tri one of the cases, mentioned by tbe latter gentleman, and in which no hemorrhage followed the removal of the limb, the irici- 2 43 sions were made four inches above the divi- sion of the dead from the living parts. Dr. Thomson has seen a still longer portion of femoral artery dosed up with coagulated blood, after a mortification of the foot and leg.; and, in one example, where the morti- fication began in the thigh, he saw the coa- gulation of the blood in tbe external iliac, extending up to the origin of this vessel from the aorta. “ So common, indeed, is this coagulation of the blood in the limbs affected with mortification (observes Dr. Thomson,) that it has been supposed to be a necessary and constant effect of Ibis disease. This opinion, however, does not appear to be well founded ; for I have now seen seve- ral instances in which a limb has mortified and dropped off, without hemorrhage having occurred from tjie vessels divided by na- 7 ture : and yet, in examining the vessels of the stumps of these patients after death, 1 have not been able to find any clots, either of coagulated blood, or ot coa .able lymph. In the cases to which I allude, the adhesive inflammation, occurring in the line of separation between the dead and living parts, had extended to the blood-vessels, and their inner surfaces being inflamed arid press- ed together by the swelling which occurs, had adhered so as to close up their extremi- ties. It is in Ibis way we shall find, that the common ligature acts, which is applied to the divided extremities of arteries and veins; and it is this obliteration, by the process of adhesion of the extremities of the arteries and veins in the neighbourhood of the spha- celated parts, that in reality prevents the occurrence of hemorrhage, when the morti- fied limbs fall off', or are removed by the knife. The coagulation of the blood in the canal of the vessel is not alone sufficient. If; may tend, in the cases in which it occurs, for a time to restrain hemorrhage ; but it is by tbe obliteration by adhesion, offthe canal in the extremities of the arteries and veins, that the occurrence of hemor rliage can be securely and permanently pro- vided against. Indeed, to me it seems doubtful, whether that coagulation of blood, which takes place in mortified limbs, ever takes place in the canal of the vessel, till its extremity and lateral communications have been plugged up by the coagulating lymph, which is extending during the state of the adhesive inflammation.” (See Thom- son's Lectures on Inflammation, p. 554.) When gangrene and sphacelus happen to any extent, the patient is usually troubled with an oppressive hiccough; a symptom well known to the surgeon of experience , and often an indication of the mischief, when external signs are less instructive The truth of this remark is frequently seen in strangulated hernise. The’ constitution also suffers immediately a considerable dejection. The patient’s countenance suddenly assumes a wild, ca- daverous look ; the pulse becomes small, rapid, and sometimes irregular; cold per- spirations come on, and the patient is often affected with diarrhoea and delirium MORTIFICATION 244 As Dr. Thomson observes, the constitu- tional symptoms “ form fevers, which par- take in individual cases, more or less, of an inflammatory, typhoid, or bilious character, lint, the degree of these fevers varies, in every particular case, from their almost total absence to the highest degree of intensity. The skin is usually hot, and dry at the com- mencement of the attack ; the tongue is without moisture, brown and hard; the pulse is quicker, and less full and strong, than in inflammation ; and this state of the pulse is often attended by flattering intermissions, and a considerable degree of subsultus ten- dinum. The fever has, in general, more of the asthenic, than of the sthenic character ; or it is more of the typhoid, than of the in- flammatory type ; a circumstance of great importance in the constitutional treatment of mortification. The fever in gangrenous af- fections is often accompanied with great un - easiness and restlessness, dejection of spirits, wildness of the looks ; and, in severe cases, with almost always more or less delirium. In the progress of the disease, cold sweats, palpitations, and convulsions, sometimes oc- cur ; a hiccough, accompanied with nausea, often comes on, and proves a most distress- ing symptom to the patient. Frequently, this hiccough is the forerunner of death. Some patients die comatose ; others, after suffering severe pain, spasms, and delirium. But, in some, a slow, in others, a sudden abatement of the constitutional symptoms takes place, accompanied also with the ame- lioration of the local affection. The gangre- nous inflammation stops, and a red line is formed by the adhesive inflammation in the extreme verge of the living parts ; the dead part separates, and granulations form , and when the constitution has strength to sus- tain the injury it has received, recovery takes place.” (See Lectures on Inflamma- tion, p. 509.) In cases of sphacelus, the prognosis chiefly depends on the nature of the cause of the disorder. The more easy the cause is of re- moval, the less room is there for alarm. It is an erroneoussupposition,that mortification arising from an external local cause is more easy to be stopped and cured, than that originating from an internal cause. The lo- cal cause is sometimes exceedingly difficult, or even incapable, of removal ; and a spha- celus, which is at first entirely local, may afterward become a general disorder, by the universal debility and derangement of the system, resulting from the complaint. Hence, it is obvious, that a sphacelus may easily ex- tend beyond the bounds of its outward local cause. On the other hand, a mortification may be reduced to one of a nature entirely local ; though it arose at first from constitu- tional causes. Sphacelus from extreme de- bility, or from such a state of the system, as attends the scurvy, typhoid fevers, he. is constantly perilous, because these causes are very difficult to remove. It is also a fact, that, when numerous causes are combined, it is an unfavourable occurrence, not merely because the surgeon is apt overtook some of them, but because there are in reality more obstacles to the cure. Humid gangrenes, which are frequently accompanied with emphysema of the cellu- lar membrane, usually spread with great ra- pidity. “ Some authors, (says a modern writer,) have attributed this to the influence of the air extricated, and Dr. Kirkland has described emphysematous gangrene, as dis- tinct from the others, and some have impu- ted this disposition, in a considerable degree, to the putrefaction of the juices, which are effused. ” With regard to the former, the author has mistaken an effect for a cause ; yet, “ it is important to recognize the fact, that gangrene, when accompanied with em- physema, has a remarkable disposition to spread.” {James on Inflammation, p. 96.) Sometimes a mortification spreads so slowly, that it does not occupy much extent at the end of several months, or even a whole year. The case, however, is often not the less fatal on this account. The dan ger is never altogether Over, until the dead part has completely separated. The en- trance of putrid matter into the circulation (says Richter) is so injurious, that patients sometimes perish from this cause, long after the mortification has ceased to spread. {An- fangsg. der Wundarzn. B 1, Kap. 3, p. 78. 79.) _ This last circumstance is very much insist- ed upon, by all the modern continental sur- geons ; but the doctrine has never gained ground among Fmglish surgeons, who enter- tain little apprehension of the bad effects of the absorption of putrid matter in cases of mortification ; and the opinion of Mr. Gu- thrie may be more correct, that nature re- ceives the shock through the nervous system, and not through the absorbents. (On Gun- shot Wounds, p. 123, Ed. 2.) The idea of a deleterious principle being absorbed was long ago well refuted by Mr. J. Burns, who pointed out, that the impression upon the constitution was in no degree com- mensurate with the size of the slough, and consequently with the quantity of putrid matter, as the effects produced by a small slough of intestine, or cornea, will exempli- fy. But when the sloughs are of equal size, and in the same parts, the differences of con - stitutional sympathy, as Mr. James observes, may depend upon the nature of the surround- ing inflammation, which, however, he con- ceives, may itself be affected by the quantity of putrid irritating fluids. {On Inflammation , p. 98.) The danger of sphacelus is also propor tioned to the size and importance of the part affected. The event of the distemper like- wise depends very much on the patient’s age and constitution. Parts, affected with gangrene, do not ini mediately lose the whole of their sensibility; the circulation is still continued in a certain degree ; and when the progress of the dis temper does not surpass certain bounds, the functions of such parts may be completely re-established. Gangrene, strictly speaking, is not a decided mortification : but only the MORTIFICATION. 245 forerunner of this latter mischief, and may he regarded as the intermediate link, be- tween the most violent stage of inflamma- tion and sphacelus. The presence of this last implies the total loss of life in the part affected, the destruction of its organization, the abolition of all its functions, and an ab- solute inability to resume them again. How- ever, even when we see the surface of a part manifestly sphacelated, we must not always conclude, that the entire destruction of its whole substance pr thickness is cer- tain ; for, in many cases, the disorder only atfects the skin and cellular substance. In this state, the integuments frequently slough away, leaving the tendons, muscles, and other organs, perfectly sound. It is only in external affections of the body that the progress of inflammation to gan- grene and sphacelus can bp marked with any degree of precision. The approaches of the latter are also not invariably announced by the distinct and manifest symptoms of gan- grene, even when the disorder is quite su- perficial. There are cases, which justify the conclusion, that a small part of the body may be affected with sudden death, just in the same manner as the whole machine. Sphacelus is often seen making its appear- ance in a part, which is apparently quite healthy, without being preceded by any other symptoms, than a sudden acute pain in the seat of the mischief. Sometimes, in the earliest period of the complaint, a black spot, which rapidly spreads on every side, is the only change that can be observed Jn order to form a just prognosis, all the above circumstances must be taken into consideration, and, in particular, we must never deliver an opinion, without having closely examined the progress of the disor- der ; for, should we make a favourable prog- nosis from such appearances. as might justify us as much as possible in so doing, there would be great risk of finding ourselves most miserably mistaken by the event of the case. In all cases of considerable mortifica- tion, even when arising from an external cause, the patient cannot be deemed exempt from danger, not only while no separation of the mortified parts has begun, but also, not before such parts have been completely detached. TREATMENT OF MORTIFICATION. I shall arrange under two heads what is to be said of the treatment of mortification. Under the first will be comprehended every thing, which relates to internal remedies, and such other means, as are indicated by the general slate of the system ; under the second, topical remedies, and the local treat- ment of the parts affected. In the treatment the surgeon will always have one thing for immediate consideration; viz. whether the case before' him is one of acute mortification, attended with inflamma- tion and inflammatory fever ; or whether it is a chronic mortification, beginning with- out fever, or attended with a fever of a ty phoid nature and great prostration of strength ? By making up his mind upon this point, the practitioner will establish an useful general principle for his guidance, especially in the commencement of the treatment. 1. When mortification is acute, and seems to depend on the violence of inflammation , the first indication is to moderate the inor- dinate action of the sanguiferous system, by the prudent employment of such means as are proper for counteracting inflamma- tion. In short, relief is to be sought in the antiphlogistic regimen, which consists in the employment of blood-letting, purgatives, diaphoretics, and diluents, and in abstinence from all vegetable or animal substances, which have a tendency to excite, or to aug- ment the febrile action It is a regimen which must be pursued, so long as inflamma- tory fever continues. It is only in cases in which the fever from the first assumes a ty- phoid character, or where the mortification takes place without the previous occurrence of fever, that any deviation from the anti phlogistic regimen can be allowed. Dr. Thomson, from whom l have borrow- ed the foregoing passage, also notices tho present common aversion to bleeding in compound fractures, erysipelas, carbuncle, hospital gangrene, burns, and frostbite , cases in which the patient, it is said, can seldom bear with impunity any considerable loss of blood. “ In many instances of these injuries and affections (says he) blood-let- ting, 1 know, is not required ; but I am doubtful, even if it were generally employed, whether it would produce all the mischiefs, which have of late years been ascribed to it. I believe it to be the most efficacious*ot‘ any of the remedies that can be employed, in all cases of inflammatory fever threaten- ing to terminate in gangrene, and that its use in such cases ought never to be omitted in the young, strong, and plethoric.” (See Lectures on Inflammation, p. 559.) When bleeding has not been sufficiently practised, during the state of the inflammation anteoe dent to the mortification ; when the general symptoms, which point out the existence of this state, continue violent ; and, especially, when the pulse is still quick, hard, or fulf ; it is absolutely necessary to empty the ves - sels a little more, even though mortification may have begun, particularly if the patient be young and plethoric. Bleeding, by dimi- nishing the fever, and abating the general heat, is frequently the best means.of all. It may then be considered better, than all anti- septics, for stopping the progress of the dis- order. But this evacuation is to be employed with a great deal of circumspection : for, should it he injudiciously resorted to, from the true state of the system not being under stood, the error may be followed by the most fatal consequences. It should also hs well remembered, that however strongly bleeding may be indicated, the moment is not far off, when this evacuation is totally inadmissible, especially if the mortification make much progress. 246 MORTIFICATION. In cases of acute mortification, after as much has been taken away as may be deem- ed safe or proper, the other parts of the antiphlogistic regimen must be continued, as long as any increased action of the heart and arteries continues. “ The use of purgatives seems to be particularly required in those cases, in which the local inflammatory affec- tion is accompanied with derangement of the digestive and biliary organs. Antimonial diaphoretics are those from which 1 should be inclined to expect most advantage in the commencement of the attack; but, after the inflammatory action has been subdued, opiates, either alone, or combined with anti- mony, or what is still better, with ipecacuan- ha, as in Dover’s powder, are frequently of singular service, not only by diminishing pain, bu* also, by inducing a soft and moist state of the skin.” {Thomson, p. 560.) A strict regimen, which may have*been useful, and even necessary, during the inflammatory stage, may have a very bad effect, if conti- nued too long, by diminishing the patient’s strength, which, on the contrary, should be supported by the most nourishing food. A vegetable diet, as Dr. Thomson ob- serves, is to be preferred in the commence- ment both of acute gangrene w ith inflamma- tory fever, and of chronic gangrene w'ith a fever from thp first of a typhoid nature. Wine and animal food given too early in dis- eases, which have a tendency to gangrene, increase the febrile heat and frequency of the pulse, oppress the stombeh, render the tongue foul, the patient restless and deli- rious, and his situation dangerous, if not hopeless. In the transition from gangrene to sphacelus, an abatement of the sympto- matic fever usually takes piace in almost all cases, which have ultimately a favourable termination Dr. Thomson beieves, that this is the first period, at which it is safe to allow vinous liquors, or diet, ckiejly animal. (. P . 561.) I next come to a second very essential and important indication, to he fulfilled, as soon as the symptoms, announcing the ex- istence of the inflammatory state, appear to abate, and the patient begins to be debili- tated. This indication i- to prevent excessive' weakness by the suitable employment of cor- dials, and, particularly, of tonics. These same means also contribute to place the system in a proper state for treeing itself from the mortified parts, or, in other words, for detaching them. For, inflammation is the preparatory step, whicli nature takes to accomplish the separation of mortified parts from the living ones, arid such salutary in- flammation cannot take place, if the ener- gies of life be too much depressed. In order to fulfil the above indication, it is necessary to prescribe a nourishing diet, with a r.-rtain quantity of good wine, propor- tio d to the patient’s strength, and the symptom- of the complaint. This diet is generally productive of more real benefit than tiie whole class of cordial and stimu- lating medicines. However, when the. pa- tient is much weakened, when the mortifi- cation of the pari affected is complete, ami the disorder is spreading to others, some of the following remedies may be ordered ammonia, aromatic confection, aether, &c In general, however, wine is best, because more agreeable than cordials ; and for this purpose, one ought to prefer the most per- fect wines, such as those of Spain and Ma- deira. Of all the medicines, hitherto recom- mended for the cure of mortification, there is certainly not one, that has acquired such a character for efficacy, as the Peruvian bark. It is said, that this remedy often stops, in a very evident and expeditious manner, the course of the disorder. Being a very powerful tonic, it is thought to operate by strengthening the system, and thus main- taining in every part the necessary tone for resisting the progress of mortification. But, w'hat x ever may be its mode of acting, the ad- vocates for this medicine contend, that it is now' a v/ell-knovvn fact, that it ought to be employed in almost all cases of mortification, as soon as the violence of the inflammatory symptoms has been appeased. It was Mr. Rush worth, a surgeon at North- ampton, who made this discovery in the year 1715. Arnyand and Douglas, two surgeons in London, soon afterward confirmed the virtue of this remedy. Mr. Shipton. another English surgeon, has also spoken, in the Philosophical Transactions, of the good ef- fects which he has seen produced by this medicine. In the Medical Essays of Edin- burgh, Drs. Monro and Paisley published several cases, illustrative of the efficacy of bark in cases of mortification. We are there informed, tfiat when its exhibition was interrupted, the separation of the eschars was retarded, and that, on the medicine being resorted to again, such a separation went on again more quickly. Since this period, all practitioners, both in England and elsewhere, have had recourse to this remedy, which has every where obtained the highest praises. Unfortunately, these praises have induced surgeons to employ it indis- criminately, and with equal confidence, in all cases. We cannot, indeed doubt, that bark has frequently had the most salutary effect, in cases of mortification, though sometimes it may probably have had imputed to it effects, which were entirely produced by nature. I he follow ing observation, made by Dr. Thomson, is highly worthy of recollection : In attending to the effects, supposed to re- sult from the operations of the external and internal remedies, w hich are daily employed for the cure of mortification, there are two facts, well ascertained, which appear to me to be peculiarly deserving of your regard. The first ot these is, that mortification often stops spontaneously, without any assistance whatever from medicine; the second, that it often begins, and continues to spread, or even after it has stopped fora while, recom- mences and proceeds lo a fatal termination, in spite of the best directed efforts of the healing art” (See Lectures on In ft a mm a {ion. MORTIFICATION. p. 55V.) In many cases, bark is evidenlly hurtful, when exhibited prematurely. There are other instances, in which it is impossible to employ it in a sufficient quantity, the sto- mach not being able to bear it in any form- In general, it should never be administered, when the pulse is high, and other inflamma- tory symptoms exist ; but, when the tension of the part diminishes, the pulse sinks, and symptoms of weakness commence, and par- ticularly, when with these circumstances, we perceive a separation beginning to take place between the dead and the living part, bark hardly ever fails to support the strength of the constitution, and powerfully to acce- lerate the separation of the mortified parts. ( Encyclop . Method. Art. Gangrene .) However, as I have already remarked, it is quite wrong to prescribe bark, in every instance, as the sole remedy ; for there are many cases, in which it is unnecessary ; some, in which it does harm ; and others, in which it is totally inefficacious. It is a medi- cine obviously of no service, when the mortification arises from an external cause, and is the only complaint, in a healthy, strong constitution. It is equally unneces- sary, when the sphacelus is of the dry sort, and has ceased to spread, at the same time, that the living margin appears to be in a state of inflammation, without any universal de- bility. But it deserves particular notice, that the circumstances of each individual case are liable to such considerable variation, that though bark may be at first unnecessary, it may afterwards be indicated. In some cases of sphacelus, bark is hurt- ful. The disorder is generally attended w ith fever, which may be of three kinds ; inflam- matory ; typhoid, or attended with extreme debility ; or one connected with a disorder- ed state of the abdominal viscera. Inthe lattercase, which isfar more common than is supposed, bark is manifestly perni- cious. Here, the indication is to empty the stomach and bowels as quickly as possible. When this has been done, if bark should now be indicated by any of the circumstances already pointed out, it may be safely admi- nistered. But there is a great necessity for procuring evacuations as speedily as possi- ble, before much debility has occurred. Sometimes, mortification is accompanied with a low typhoid kijs-d of fever, which, whether the cause, or the consequence of the local mischief, demands the exhibition of bark. However, mortification may be attended with common inflammatory fever, and then the living margin is generally inflamed and painful. This is particularly the case, when mortification is the consequence of genuine acute inflammation, or of an external injury in a healthy subject. Here, bark must ob- viously be injurious. Still, it is wrong to regard this medicine as invariably hurtful, whenever sphacelus is the effect of inflam- mation. It has already been observed, that the inflammation frequently has less share in the origin of the disorder than gome inci- dental cause, which oftentimes requires the exhibition of bark. Even when mortifica - tion is the pure effect of inflammation, great prostration of strength may subsequently arise, and indeed does mostly take place at. a certain period of the disorder. In this cir- cumstance, the voice of experience loudlj' demands the employment of bark, though its exhibition would have been at first use- less or hurtful. While genuine inflamma- tory fever, and local inflammation, are co- existent with mortification, antiphlogistic means are undoubtedly useful ; but, great caution is requisite, since, in cases of humid gangrene, as it is termed, the inflammatory state very soon changes into one, in which the great feature is prostration of strength. When there is mere prostration of strength . without any symptom of gastric disorder, or of inflammation, or typhoid fever, bark is evidently proper, though seldom effectual alone ; diaphoretic, and nervous medicines being also proper, opium, wine, camphor, ammonia, brandy, &lc. The constitutional disorder may be either inflammatory, ty- phoid, or on6 connected with gastric disor- der. Consequently, there are three plans of constitutional treatment, and it is easy to determine the particular cases, in which bark is unnecessary, hurtful, or ineffica- cious. We meet with one species of mortifica- tion, in which the patient experiences se- vere pain in the part, w ithout the smallest appearance of inflammation. Here bark is never of any use, and opium is regarded as the only medicine of much efficacy. This subject will be more fully considered pre- sently, when Mr. Pott’s remarks on a pecu- liar mortification of the toes and feet will be introduced. Bark sometimes occasions purging, and then it also proves inefficacious and hurtful. This effect, however, may frequently be prevented by adding a few drops of lauda- num to each dose. Bark often disagrees wdth the stomach ;. but it less frequently does so, when given in an exceedingly fine powder, which also generally proves most inefficacious. Also the administration of bark with w ine, some aromatic water, or in the form of the cold infusion, is less likely to disorder the sto rnach. (Richter, Anfangsgr. dcr Wundarzn . Kap. 3.) Several years ago I published a critique on the indiscriminate employment of bark in cases of mortification, and my remarks were inserted in the article Gangrene in Dr. Rees's Cyclopaedia. Many of them were in- troduced into the 2d edition of this Surgical Dictionary, printed in 1813. (See Cinchona.) Since this period, I am happy to find, that the blind enthusiasm with which bark was prescribed is beginning to subside, and that on this subject some eminent surgeons have of late publicly avowed sentiments, which entirely coincide with my former state- ments. I think (says Dr. Thomson) ! have frequently seen it prove hurtful, when ad- ministered in cases of mortification, by load- ing the Stomach of the patient, creating a 248 MORTIFICATION dislike to food, and sometimes by exciting an obstinate diarrhoea. I believe il to be, in mortification , a medicine completely inert and inefficacious.” (See Lectureson Inflammation, p. 563.) By this expression, Professor Thom- son does not mean to say that bark can ne- ver be useful in cases of mortification, but only that it has no specific power in check- ing the disorder, as many have erroneously inculcated. a Bark (says Professor Boyer) has been considered by several distinguished English practitioners, as a true specific against gan- grene in general, and especially against that which depends upon an internal cause ; but, subsequent observations to those published in England have proved, that it has no power over the immediate cause of gan- grene, and that it only acts as a powerful tonic in stopping the progress of the disor- der, and promoting tbe separation of the mortified parts.” (See Traiti des Maladies Chir. T. 1 .p. 151, Paris , 1814.) Boyer alscP particularly objects to bark being given while inflammatory fever prevails ; but, whenever he prescribes bark in cases of mortification, he seems to entertain the old prejudice of expecting benefit in proportion to the quantity which can be got into the stomach. On the contrary, Mr. thrie de dares, that he has not found hark useful, “ further than as a tonic, and given in such quantities as not to overload the stomach.” (On Gunshot Wounds , p. 148, Ed. 2.) a plan which I have always recommended. For further observations on bark, the reader is referred to the article Cinchona. The sulphuric acid may frequently be ad- vantageously given at the same time with the bark, and the best method of exhibiting it is to acidulate with it every thing w^hich the patient drinks. Other acids are also sometimes used for the same purpose. Carbonic acid gas is another remedy of the highest efficacy in cases of chronic mor- tification. It has even been knowm to have the most beneficial effects when bark has failed in doing good. Water impregnated with this gas should be recommended, as a most beneficial kind of drink. The hospital gangrene is a case for which bark has been much recommended. The best mode of treating this particular case, how-ever, has been detailed in a separate article. (fsee Hospital Gangrene.) A third indication, which should be ob- served together with the second, or which should even precede it in many instances, is to lessen the irritability and sufferings of the patient, by the use of opium. Attention 1 o this desideratum frequently contributes more than any thing else to stop the pro- gress of the disorder, and is often indispen- sable in order to promote the operation of other remedies. In all cases of mortifica- tion, every thing wdiich heats, irritates, or adds to the patient’? sufferings, appears, in general, to augment the disorder, and in- i' crease the rapidity of its progress. On the other hand, every thing which tends to calm, assuage, and relax, frequently retards the progress of mortification, if it produce no greater good. The pain also, which is a constant mark of too much irritation, con tributes of itself to increase such irritation and, in this double point of view, w r e can not do better, in the majority of cases, than endeavour to appease it by the judicious and liberal use of opium. When the inflamma- tory stage evidently prevails, tlm medicine may be conjoined with antiphlogistic reme- dies, such as the nitrate of potassa, antimo- ny, &tc. In other instances, attended w ith debility, it may be given with bark and cor- dials. Mr. Pott has described a species of morti- fication, for which bark is most frequently ineffectual, and opium the remedy which is to be depended upon. It is that particular kind, which, beginning at the extremity of one or more of the small toes, does, in more or less time, pass on to the foot and ankle, and sometimes to a part of the leg, and, in spite of all the aid of physic and surgery, most commonly destroys the patient. It is very uniike the mortification from in flammation, that from external cold, from ligature, or bandage, or from any known and visible cause, and this as well in its attack as in its progress. In some few instances, it makes its appearance with little or no pain ; but, in by much the majority of these cases^, the patients feel great uneasiness through the whole foot and joint of the an- kle, particularly in the night, even before these parts show any mark of distemper, or before there is any oiher, than a small dis- coloured spot On the end of one of the little toes. It generally makes its first appearance on the inside, or at the extremity of one of the smaller toes, by a small black or blueish spot : from this spot the cuticle is always found to be detached, and the skin under it to be of a dark red colour. If the patient has lately cut his nails, or corn, it is most trequently, though very un- justly, set to the account of such operation. In some patients, it is slow 7 and long in passing from toe to toe, and from thence to the foot and ankle ; in others, its progress is rapid and horridly painful : it generally begins on the inside of each small toe, be- fore it is visible either on its under or upper part; and when it makes its attack on the foot, the upper part of it first shows its dis tempered state, by tumefaction, change of colour, and sometimes by vesication ; but wherever it is, one of the first marks of it is a separation or detachment of the cuticle. Each sex is liable to it; but, (says Mr Pott) £: for one female in whom I have met. with it. I think I may say, that I have seen it in at least twent) males. I think also that 1 have much more often found it in the rich and voluptuous, than in the labouring poor more often in great caters, than free drink - ers. It frequently happens to persons ad- vanced in life, but is by no means peculiar to old age. It is not, in general, preceded or accompanied by apparent distemperaturo either oftflPhe part, or of the habit. I do no MORTIFICATION 241 ) know any 'particular kind 01 constitution which is more liable to it than another ; but as far as my observation goes, l think that I have most frequently observed it to attack those who have been subject to flying un- certain pains in their feet, which they have called gouty, and but seldom in those who have been accustomed to have the gout re- gularly and fairly. It has, by some, been supposed to arise from an ossification of vessels', but for this opinion I never could find any foundation but mere conjecture.” In this article 1 have already stated the observations of Cowper, Dr. Thomson, and Mr. Hodgson upon the ossified state of the arteries in this species of mortification. The facts, recorded by the two latter writers, at least prove, that the opinion is founded, not upon mere conjecture, as Mr. Pott alleges, but upon actual observation and experience. With respect to the insufficiency of Peru- vian bark, Mr. Pott observes : “ I believe I may venture to say, that I have tried it as fairly, as fully, and as' variously as any man has or can ; * I have given it in the largest quantity, at the shortest intervals, and for the longest possible space ; that is, as long as the patient’s life would permit : I have given it by itself iu decoction, extract, and substance ; I have combined all these toge- ther; l have joined it with nitre, sal. ab- synth. with snakeroot, with confect, car- diac. with volatile salts, and with musk, as different circumstances seemed to require, or admit ; 1 have used it as fomentation, as poultice, as dressing ; I have assisted it with every thing which has been usually thought capable of procuring or assisting digestion ; still the distemper has continued its course, perhaps a little more slowly, but still it has ended in death.” Mr. Pott afterward relates the first cases in which he gave opium. His plan was ge- nerally to give one grain every three or four hours ; but never less than three or four - grains in the course of four and twenty hours. Mr. Pott, however, did not propose opium as an universal infallible specific ; but only as a medicine which would cure many cases not to be saved by bark. The observations of Mr. Pott on the local treatment of these cases are of great practi- cal importance : no part of his writings has a stronger claim to attention. “ I have found (says he) more advantage from frequently soaking the foot and ankle in warm milk, than from any spirituous or aromatic fomentations whatever ; that is, I have found the one more capable of allevi- ating the pain which such patients almost always feeT, than the other; which circum- stance I regard as a very material one. Pain is always an evil, but, in this particular case, 1 look upon it as being singularly so. Whatever heats, irritates, stimulates, or gives | uneasiness, appears to me always to increase ‘ the disorder, and to add to the rapidity of j its progress ; and, on the contrary, I have | always found, that whatever tended merely I to calm, to appease, and fo relax, at least I retarded the mischief; it it did no more. ! Vot. il. 'S2 “ The whole plan ot the chirurgic treat- ment ol this disease is founded on a general idea of warming, invigorating, stimulating, and resisting putrefaction ; and the means generally made use of are very proper for such purpose : but 1 must own that I think the purpose, or intention, to be improper.” Mr. Pott afterward observes: “ Cases ex- actly similar, in all circumstances, are not to be met with every day, but I am from expe- rience convinced, that of two, as nearly similar as may be, in point of pain, if the one be treated in the usual manner, with a warm, stimulating cataplasm, and the other only with a poultice made of the fine farina seminis lini, in boiling milk or water, mixed, with ung. sambuc. or fresh butter, that the pain, and the progress of the distemper, v wiil be much greater and quicker in the former than in the latter. “ When the black or mortified spot has fairly made its appearance on one or more of the toes, it is the general prfctice to scarify or cut into such altered part with the point of a knife or lancet. If this incision be made merely to learn whether the part be mortified or not, it is altogether unnecessary, the detachment of the cuticle, and the colour of the skin, render that a decided point : if it be not made quite through the eschar, it can serve no purpose at all : if it he made quite through, as there is no confined fluid to give discharge to, it can only serve to convey such medicines as may be applied for the purpose of procuring digestion to parts capable of feeling their influence, and on this account they are supposed to be beneficial, and therefore right. “ When the upper part of the foot begins to part with its cuticle, and to change colour, it is a practice with many to scarify imme- diately ; here, as in the preceding instance, if the scarifications be too superficial, they must be useless ; if they be so deep as to cause a slight hemorrhage, and to reach the parts which have not yet lost their sensi- bility, they must do what indeed they are generally intended to do, thift is, give the medicines, which shall be applied, an opportunity of acting on such parts. “ The medicines most frequently made use of for this purpose are, like the theriaca, chosen for this supposed activity ; and con- sist of the warm, pungent oils and balsams, whose action must necessarily be to stimu- late and irritate : from these qualities they most frequently excite pain, which, accord ing to my idea of the disease, is diametri- cally opposite to the proper curative inten tion ; and this I am convinced of from re- peated experience. “ The dressings cannot consist of materi als which are too soft and lenient ; nor are any scarifications necessary for their appli- cation. But I would go farther and say, that scarifications are not only useless, but, in my opinion, prejudicial, by exciting pain, the great and chiefly to be dreaded evil in this complaint. The poultice should be also soft, smooth, and unimtating ; its in- tention should be merely to «oftcu and relax . M0JKT1F1CATI03S. i( should comprehend the whole foot, ankle, and part of the leg and should always be so moist or greasy as not to be likely to be- come at all dry or hard, between one dress- ing and another.” When the toes arc, to all appearance, perfectly mortified, and seem so loose as to be capable of being easily taken away, it is, in general, thought right to remove them. But, however loose they may seem, if they be violently twisted olF, or the parts, by which they hang, be divided, a very con- siderable degree of pain vviil most common- ly attend such operation, which therefore had much better be avoided ; tor Mr. Fott has seen this very pain, thus produced, bring on fresh mischief, and that of the gangre- nous kind. If the patient does well, these parts will certainly drop off ; if he does not, no good can arise from removing them. (Pott's Works.) In case*, in which the disorder is attended with a great deal of irritation, many subse- quent practitioners have attested the efficacy of opium ; though it has not always had the same success in their hands, when the mortification depended chiefly on constitu- tional debility. Dr. Kirkland observes, that we must be careful not to force the doses, especially at first ; and that the medicine does more harm than good, when its sopo- rific effects go so far as to occasion delirium, take away the appetite? or cause affections of the heart. Some authors have also recommended the use of camphor, which, by reason of its narcotic virtue, has sometimes produced good effects. Pouteau attributes consider- able efficacy to it. especially in the erysipe- latous gangrene arising from wounds. In such cases, he recommends it to be given in the dose of live grains, with a double quantity of nitre, every four hours. Few surgeons of the present day believe, that opium possesses as much power in the preceding cases, as Mr. Pott represented. While Dr. Th Anson allows, that opium is much more entitled to the attention of practitioners than bark, as an useful medi- cine in the treatment of mortification, yet, “in saying so much in favour of opium, (he observes,) I would not Jby any means have you to place the same reliance on its powers for stopping, even the mortification of the toes and feet in old people, which appeal's to have been done by Mr. Pott. From the trials which I have made, and which I have seen made by others, 1 cannot allow myself to believe, that its powers in stopping this particular sort of mortification are greater, than in stopping any other form, or variety of the disease. It is obvious, however, from Mr. Pott’s account, that his mind was strong- ly impressed with a very different opinion. His opinion seems to me to have been form- ed from the results of*a very small number of cases, and in complete forgetfulness of the invaluable observations of his preceptor Mr. Sharp, with regard to the frequent spon- taneous stoppage of mortification in cases in which no medicines whatever are used.' (See Thomson's Lectures on Inflammation , p. 568.) 2. With respect to the external, or local treatment of mortification, the first indication consists in removing, if possible, such ex ternal causes, as may have occasioned, or kept up the disorder ; as the compression of bandages, ligatures, tumours? all irritating substances, &c. When mortification arises from inflamma- tion, which still prevails in a considerable degree, it is evident, that the dead part itself only claims secondary consideration, and that the principal desideratum is to prevent the mortification from spreading to the living circumference, by lesseningthe inflammation present. Henee, under such circumstances, the application of linen, wet with the satur- nine lotion, and the maintenance of a con- tinued evaporation, from the inflamed parts surrounding the mortified flesh, must be just as proper as if the mortification itself did not exist, and were quite out of all con- sideration. It has been justly remarked by an eminent man, ( Hunter ) that the local treatment of mortification, (meaning that in consequence of inflammation) has been as absurd as the constitutional ; scarifications have been made down to the living parts, in order that stimu- lating and antiseptic medicines might be applied to them such as turpentines, the warmer balsams, and sometimes the essential oils. Warm fomentations have been also applied, as being congenial to life ; but, warmth always increases action, and should, therefore, be well adjusted to the case ? for, on the other hand, cold debilitates or lessens powers, when carried too far, though it first lessens action. Stimulants are likewise im- proper, as the actions are already too violent. It is proper to keep the parts cool, and all the applications should be cold. In cases of mortification from inflammation, good effects have also been seen to arise from the topical, as well as internal employment of opium. But it must be acknowledged, that how- ever proper the employment of cold appli- cations may be in principle, in cases of mortification, attended with inflammation, fomentations and emollient poultices are most commonly preferred in practice. Besides common poultices, there are several others, which have acquired great celebrity, as topical applications In cases of mortification. Of this kind are the cata- plasma carbonis,* cataplasnia cerevisiae,f and the cataplasma eft'ervescens.t These local remedies are, perhaps, in nine cases out of ten, superior to all others. With respect to stimulating and spirituous applications, such as brandy, spirit of wine, * Prepured by mixing' about oz. ij. of finely powder- ed wood-charcoal with half a pound of the common linseed poultice. t Prepared by stirring into the grounds of strong beer ns much oatmeal, as will make tbe mass of a suita- ble consistence. + prepared by stirring into an infusion of malt ns much oatmeal, as will render the substance of a proper thickness, and then adding about a siroonfulof vest. MORTIFICATION 251 balsams, resins, and aromatic substances, which have been recommended by a vast number of authors, they are almost entirely laid aside by modern practitioners. Though such things are indeed really very useful in preserving dead animal substances from becoming putrid, a very little knowledge of the animal economy is requisite to make us understand, that they cannot act in this manner on parts still endued with vitality; but, on the contrary, that they must have highly prejudicial effects, in the cases under consideration, by reason of the violent irrita- tion which they always excite, when applied to the living fibres. It may now and then, however, be justifiable to apply spirituous applications to the dead parts themselves with a view of diminishing the fetid effluvia, which, by contaminating the air, have some share in injuring the patient’s health ; but the greatest care is requisite to keep these stimulants from coming into contact with the living surfaces around and beneath the sloughs. There are a few surgeons, however, who still place confidence in certain stimulating applications. ■“ in the less acute and more chronic cases of gangrenous inflammation, as in malignant erysipelas and carbuncle, in the gangrene of the toes and feet of old peo- ple, in the sphacelating state of hospital gan- grene, and in severely contused wounds, in which gangrene and sphacelus have super- vened, the emollient poultice, which is ap- plied to promote the separation of the dead parts, may have an addition made to it of a greater or less quantity of the unguenturn resinosum, or even of oil of turpentine itself. In the more severe of these cases, where we have reason to dread the extension of the sphacelus, warm dressings, as they have-been termed, which are formed by dipping pled- gets of ebarpie in a mixture of equal parts of the unguenturn resinosum and oil of turpen- tine, may be applied, of a temperature as hot as the patient can bear without pain ; and over thgse we may lay an emollient poultice, of a large size and soft consistence. u After the sphacelus stops, aqd the pro- cess of ulceration begins in the inflamed line -of contact, between the dead arid living parts, it will often be found, that the turpen- tine dressings are too stimulating, and occa- sion a considerable degree of pain. When this happens, we must either diminish the quantity of the turpentine in the dressings, or remove it altogether, according to circum- stances. Besides the pain, a considerable extension of the ulceration would be, in general, the effect of continuing these appli- cations after they begin to produce uneasi- ness. The ulcerating surface is, in the pro- gress of separation, liable to pass under every mode of treatment, into the state of a painful and irritable ulcer; and in this state, it may require to be treated with decoctions of poppy-heads, or with the application of the turnip, carrot, fresh hemlock leaf, stale beer, fermenting, poultices, fee.” (See Thomsons Lectures, p. 577 , 578.) The hospital gangrene is undoubtedly a case, which requires powerful applications, like Fowler’s solution of arsenic, or the un- diluted mineral acids ; and, in Guy’s Hospi- tal, phagedenic sloughing ulcers are usually treated by Sir A. Cooper with the nitric acid lotion, 50 drops to a quart of water, and the internal exhibition of the subcarbonato of ammonia. The cases also teTmed sloughing phagedeenaby Mr. Welbank, find considered by him as analogous to hospital gangrene, may be cured by dressing them with the un- diluted nitric acid. (See Med. Chir. Trans. Vol. 1 1.) I conceive, that it has only been in hospital gangrene, and other cases of sloughing phagedenic ulcers, that various acids, diluted, or undiluted, other caustic substances, and the actual cautery, have sometimes proved really serviceable The muriatic acid, diluted with six times its quantity of water, was particularly recom- mended by Van Swieten, who applied it after making scarifications. In this manner, he stopped a slpughlng disease extending all over the scrotum and penis. This author strongly recommends the same topical ap- plication to the sloughy state of the gums in cases of scurvy. In this kind of case, he mixed the muriatic acid with honey, in vari- ous proportions ; sometimes, he even em- ployed the pure acid itself for touching the. parts, which were likely to slough. It is also by supposing, that the diseases referred to, were of a phagedenic character, that I account for the good effects, imputed by Dr. Kirkland and others, in cases of mortifica- tion, to another still more active caustic, namely, a solution of mercury in nitrous acid, with which the edges of the living flesh were touched. At all events, if the diseases were common cases of sloughing, I infer, that such remedies were not really necessa- ry, and that nature triumphed both over the disease and the supposed remedy The fol- lowing is a case related by Dr. Kirkland : A man met with a fracture of the fore- arm, and the ends of the bones projected through the integuments. The fracture was very expeditiously reduced ; but, at the end of five or six days, the whole arm seemed to be completely mortified up to the shoul- der. Amputation was performed as near the joint as possible, and the stump, which had mortified as far as the acromion, was cauterized. The following day the mortifi- cation had reached the inferior extremity of the scapula. A little of the solution of mer- cury in nitrous acid was now applied, by means of a probe, along the edges of lh*e parts affected, and from this moment the dis- order made no further progress. This cau- terizing was repeated every day, for seven teen or eighteen days. The sloughs, and even the scapula itself, were detached, and the patient got well. On the continent, liquid caustics are some- times used as topical applications to gangre- nous diseases, more especially, however, in cases of hospital gangrene, and malignant carbuncle. Of this last disorder, Larrey has recorded a very dangerous example, in which lie effected a cure by fr bounded by an inflammatory line. (bee Mem. de Chir. Mil. T. 3, p. <55 — 72.) In the article amputation , notice has been taken of a sloughing, which commences in the loot, and extends up the leg, and sometimes follows gunshot injuries of the thigh, which involve the femoral artery : this is a case particularly instanced by Mr. Guthrie, as re- quiring the very early performance of am- putation. Sir Astley Cooper also refers to cases, in which the rule was successfully de- viated from, of noi amputating, before limits nre set to the spreading of mortification ; the instances in question arose from injury of blood-vessels, and other local violence, in patients of a healthy constitution. In such cases, it is admitted by this very experienced surgeon, that the practice should be different from what is usually pursued in mortification from constitutional causes. ( Surgical Essays , Part 2, p. 1S6.) Fabricii Hilda ni Traci. Method tens de Gan- grcena et Sphacelo. Quesnai, Traile de la Gangrene , 12 mo. Paris , 1749. Encycloptdie Meihodique , Parlie Chirurgicale , Art. Gan- grene. Kirkland on Gangrene, and on the Present State of Medical Surgery. Richter , An fangsgr. der Wundarzn. B. i , Kap. 3. Various parts of Hunter on Inflammation, fyc. Sharp's Critical Inquiry into the present Slide of Surgery , Chap. 8. Richtrand, Nosographie Chir. T. 1, p. 215, fyc. Edit. 4. Lassus , Pa- thologic Chir. T. 1 , p. 30, fyc. Edit. 1809. Levtillt, JYouvelle Doctrine Chir T. 4, p. 321, dye. Paris, 1812. Larrey, Mtmoires de Chirurgie Militaire, T. 3, particularly the Mdm.sur la Gangrene de Congelation, p. 60, and that sur la Gangrene Traumaiique,p. 141. Callisen, Systema Chirurgice Hoditrnce, Vol. 2, p. 374, Edit. 1800. Dr. J. Thomson's Lectures on Inflammation, p. 501, Edinb. 1813. O’ Halloran on Gangrene and Sphacelus , 8 vo. Dublin, 1765. Pott's Obs. on the Mor- tification of the Toes and Feet in his Ch irurg. Works, Vol. 3. J. Kirkland , Thoughts on . Imputation , <*yc. with a short Essay on (he Use of Opium in Mortification, 8 vo London, 1780. J. Harrison, The remarkable Effects affixed Air in Mortifications of the Extremi- ties, Sro. Loud. 1785. ./ A. Murray, In Gangnenam Scroti Obs. {Frank. Del. Op. 10.) C. White, Observations on Gangrenes and Mortifications, accompanied, fyc. with convul- sive spasms, 8 vo. 1790. Pearson's Principles of Surgery, p. 114, Edit. 2. Lawrence in Medico- Chir. Trans. Vol. 6, p. 184, fyc. Del- pech , Mdmoire sur la Complication des Plaies cl des Ulceres, eonnue sur le Norn de Pov.rri- ture d'Hopital ; also, Precis Element air 6 des Maladies Reputees Chirurgicales, T. 1 , p. 73, fyc. Paris, 1816. Boyer, T raites des Ma- ladies Chir. T. 1, p. 105, fyc, Paris, 1814. John Bell's Principles of Surgery. Professor Himly's Abhandlung uber der Brand der Weichen und harlen Thtile, Git. 1800. For an Account of the dry gangrene, see particu- larly the Writings of Hildanus, Tulpius, Quesnai Mtmoires de la Sociele Roy ale de Medecine, Tom. 1. Operc di Bertrandi ; Me- dical Museum, fyc. For a description of the mortification caused by eating cockspur rye, see Vox If 33 Dodard's letter in Journal des Savans, 1676, Noel, in Mem. de TAcad. des Sciences, 1710. Langius. “ Descriptio Morborum ex esu Cla- vorum Secalinorum." Duhamel, in M6m. de TAcad. des Sciences, 1748.' Dr. C. Woolaston , in Philosophical Trans. 1762. Tessier, in Mtm. de la Societt Royale de Medecine, T. i, and 2, tfc. 0. Presscott, A Dissertation on the Natural History and Medicinal effects of the Secale cornutum. or Ergot. 8 vo. Land. 1813. D. F. Heffter , Doctrines de Gangrana brevis Expositio, 4 to. Lips. 1807. C. L. G Liessehing, De Gangrana, 4lo. Colt. 1S11. Hennen's Principles of Military Surgery , p. 241, &pc. Ed. 2, 8 vo. Loud. 1820. G. J. Guthrie on Gunshot Wounds, fyc. p. Ill, 8fc. Ed. 2, St’o. Loud. 1820. J. H. James, Obs. on the Principles of Inflammation, p. 84.287, dye. 8vo. Land. 1821. Sir Astley Cooper, Surgical Essays, Part 2, p. 186, Sro. Loud. 1820. MOXA. A soft lanuginofrs substance pre- pared from the young leaves of a species of mugw’ort. It is used in the following way : A little cone of the moxa is laid upon the part, previously moistened, and set on fire at the top. It burns down w ith a temperate glowing heat, and produces a dark-coloured spot, the separation of which is promoted by applying a little garlic. The ulcer is left to discharge, or is healed up according to the object in view. The moxa is famous in the East for curing several diseases ; and the French are much in the habit of using it ; but, when English surgeons wish to produce a slough, they generally have recourse to caustics, in preference to actual fire. M. Roux, when he visited the London hos- pitals, had two opportunities afforded him of applying the moxa, in order to convince the rising generation of surgeons in this country of its superior efficacy. The first was in a ca-e of spontaneous paralysis of the deltoid muscle at St. Bartholomew’s. The moxa was applied a lit ? le below the acro- mion, and a few T days afterward the motion of the arm began to be restored. This, however, was a case, which, according to (he account of Roux himself, had relapsed, after having been cured by other means. I think one of the surgeons of St. Bartholo- mew's informed me, that notwithstanding the moxa, the relief proved again only tern-, porary. If, however, the moxa had suc- ceeded, a caustic issue, a blister, or volatile liniments, would probably have answered equally well. The second instance, in which M Roux applied the rnoxa, was a case of white swelling at Guy’s Hospital ; but the disease had advanced too far to allow any hope of •* favourable issue. (See Voyage fait a Londres en 1814, ou Par allele de la Chirurgie Angloise avec la Chirurgie Fran - caise, p. 19, 20 ) M. Roux flatters himself that, “ Its chirurgiens Anglois repugneront sans doute moins a I'avenir a faire usage du moxa." The truth is, English surgeons, as well as English farriers, knew very well be- fore the arrival of M. Roux what might be done with moxa and the actual cautery. But, though the application of fire still pre MURIATIC ACii*. vails in Hie veterinary art, as a mode of disease, in which a cure tons' effected without curing diseases, it has long been abandoned as a means of relief in the English practice of surgery : not on the ground of its being always ineffectual ; but, because equal good has been found to result from measures, which are milder, always less terrific, and frequently less painful. In order to con- vince an English surgeon that moxa and the actual cautery ought to be introduced into practice, M Roux should prove, that there is at least some particular disease, which may in this manner be cured, but which cannot be cured by other means, ordinarily em ployed in our practice. He should also make us forget, that the application of actual fire was once as common in English surgery as in French ; but that it had not attractions enough to maintain if- ground. MURIATIC ACID. Acidum Muriaticum. Gargles, containing this acid, are often made use of with advantage in various cases of sore throat, and the disease known by the name of eancrum oris. The following for- mula is employed at St. Bartholomew’s Hos- pital. JJ. Rosas rubrae exsiecatae 3m t his disorder. Childhood and puberty, how- ever, are the periods most liable to it. The same thing may l^said ot persons, who la- bour hard, and aremiuch exposed to external injuries. Every bone of the human body is subject Ui necrosis ; but those which are superficial, and enter into the formation of the extremities, are more frequently affected than others whose situation is deeper. Ne- crosis less commonly attacks the spongy substance of the bones, because this being endued with a. higher degree of vascularity and life, suppuration is most apt to occur. Necrosis, on the contrary, is oftener seen in the compact substance, where the vital prin- ciple is less energetic, and more readily ex - tinguished. Lastly, tbe disorder may affect the long bones, or the broad ; the large oe small ; and even ttiose of the very least size ; ince it is well known, that the ossi- cula of the ear m v be destroyed by necrosis, and separate. I have seen this happen in two instances, and the fact is recorded by several writers. (See As true de Morbis Ve - nereis, lib. 4. cap. 1. Henri , Journal dran, Duverney, Trioen, Gunther, Ludwig, Mi- chael, Bousselin, Weidmann, Russell, Whately, Desault, &,c. See the works refer- red to at the end. Dr. Hunter mentions a tibia which was sent to him by a Mr. Inett, after amputation. On examination, the case at first sight seem- ed to be a swelling of the whole bone, with a loose internal exfoliation. However, it proved to be a remarkable instance of the separation of the greatest part of the origi- nal bone, whose place was supplied by a callus. The external surface of the enclo- sed loose piece of bone was smooth. A small part of the surrounding bony substance being removed, the contained piece was taken out, and found to be the whole body of the tibia. It had separated from the epi- Necrosis. 269' pbysis at each extremity. The middle part of the bone had perished, consequently, had lost its connexion witli the periosteum, and was gradually thrown off from the living parts of the bone at each end. A callus ex- tended from end to end, united the two ex- tremities of the original tibia, preserved the length, and gave firmness and inflexibility to the part. The exfoliation was so encom- passed by the new bony case, that though quite loose, it could not be thrown out. (Med. Obs. and Inq. Vol. 2.) Weidmann saw a shoemaker, who, after much suffering, extracted himself the great- est part of the diaphysis of the tibia ; yet, the loss wa3 so well repaired, that the man could walk afterward nearly as ably as ever- (De Necrosi Ossium,p. 29.) “ We are not to imagine, (says Weid- mann) that these regenerations happen by chance : experiments made upon living ani- mals by Troja, Blumenbach, Koehler, De- sault, and myself, prove that they invariably follow certain laws.” In fact, whenever the medullary structure of the long bones of pigeons, or dogs, is destroyed, these bones become affected w ith necrosis, and are afterward reproduced to the full extent of their destruction. The observations and experiments, cited by Weidmann, also prove, that it is the long bones which are usually reproduced ; though the flat ones are not entirely destitute of the power of regeneration, since experience fully evinces, that, when a portion of the skull is removed, either by a wound, by disease, or by the trepan, nature always endeavours to cover the deficiency, the edges of the aperture extending themselves by means of a bony substance, furnished by the periosteum, the dura mater, and cranium itself. (Tenon Mem. de l' Acad. des Sciences, 1758, p. 412, 413, 415, 416, 418.) But still the reproduction is imperfect, as a space unfilled up is always left, even when the bone has lost only a small piece, like what is taken out by the trephine ; and when the destruction of the cranium is very extensive, no reproduction at all happens. This fact is proved by examples mentioned by 5avi- ard,Pott, Sabatier, &tc When in a case of necrosis, says Weid- mann, a scale or table, of either a long or flat bone, is separated, no regeneration fol- lows, because the granulations, which rise up under the sequestrum, then serve as a periosteum, and as soon as the dead bone 19 removed, they become united to the ad- jacent parts. It is likewise ascertained, that the power of reproduction in the bones is particularly active in the early periods of life, and in healthy subjects ; and that it is languid and even annihilated in old persons, pregnant women, (Bonm Thesaur. p. 174,) and in ve- nereal. cancerous, and rickety patients. ( Callisen , Syst. Chir. Hodiernce , Pars 1, p. 636.) In order that a new bone may form, the periosteum and other membranes, concern- ed in the ^nutrition of the original bone, must have been spared from destruction. In fact, continues Weidmann, we observe that in cases where the tube of a long bone has suffered necrosis, the bone is never repro- duced, when the periosteum has been de- stroyed by inflammation or other causes. Surgeons ought also to understand that it is not always a reproduction which has hap- pened, when a part of a bone perishes ; not even when a tubular portion of a long bone dies, and is contained in the medullary canal. For, says \\ eidmann if the inner- most layers of a long bone perish, while those which compose, as it w ere, the bark, are preserved, the latter swell and soften, as if they were actually a new bone. Se- veral round apertures are observable upon their surface, w'hieh serve for the transmis- sion of vessels, and are larger than those which perform this office in the natural state. There are likewise formed large openings, or fistulae, which, as in a new bone, lead to the medullary canal. Here it would be erroneous to conclude that a new bone has been produced, and a very little attention will discover that all is limit- ed to some changes in the external part of the bone, which the necrosis has not affected. When, therefore, the interior of the canal of a long bone is destroyed by a necrosis, which does not extend to the external lay- ers, the case is not a reproduction of the bone. When, however, w 7 e find the tube of any long bone included in a sort of osseous shell, and the surface of this tube smooth, like that of a bone in the natural state, we may be certain that it has been detached directly from the periosteum, and that the bony shell w hich contains it, is a new production. On the contrary, if the surface of the dead tube is rough, we may infer that the separa- tion has taken place between the innermost layers of the bone and those which are superficial, the latter composing now the osseous shell, in which the sequestrum is included. (Weidmann De A r ecrosi Ossium, p. 31*) This fhst theory, concerning the produc- tion of the osseus shell in necroses of the long cylindrical bones, is adopted by Riche- rand as the true one, not only in the in- stances specified by Weidmann, but in every other example w here the old bone seems to be included in another which has the ap- pearance of being a new’ production, and which w as supposed by Troja, David, &c, to be formed by the vessels of the perioste- um. (See JYusographie Chir. T. 3, p. 158, 161, Edit. 4.) Boyer does not espouse this theory exclusively ; but represents the thing as sometimes happening. (See Traiti des Mai. Chir. T. 3 ,p. 426.) As far as the observations of Weidmann informed him, the short or cuboid bones do not appear to be capable of reproduction. (P. 31.) Duverney mentions an astragalus, w 7 hich was destroyed by necrosis , but does not state that any substitute for it was after- 270 NECROSIS. ward formed. ( Trait6 des Maladies des Chir. Os. p. 458.) Weidmann also never witnessed a repro- duction of the spongy substance, such as it was before its destruction, round the me- dulla. He always found the substituted matter dense and compact, at least for some time after its formation. It is now admitted, however, that in pro cess of time, the inner surface of the new bone becomes cellular, and is lined with a membrane containing medulla. The rege- neration of the medulla was first observed by Koehler, and afterward in an extensive series of experiments, which Professor Thomson made with Dr. Alexander McDo- nald, and which were published in the lat ter gentleman’s inaugural dissertation, in 1799. (See Thomson's Lectures on Inflam- mation. p. 393.; Mr. Russel does not ap- pear to adopt this opinion concerning the regeneration of the medulla; for, he states that, after the absorption or removal of the sequestrum, the cavity of the new bone be- comes filled up with granulations, which are at length converted into bony matter Thus, be says, the new bone differs from the ori- ginal one, in being solid instead of hollow. Authorities, however, are decidedly against Mr. Russell on this point : in the 5th vol. of the M6m de VAcad. de Chir. is the history of a man, the whole of whose clavicle came away without his being deprived of any of the motions of the arm. The death of this patient, which happened shortly afterward, afforded an opportunity of examining how nature had repaired the loss. Another cla- vicle was found regenerated, which neither differed from the original one in length nor solidity ; but only in shape, being flatter, and not so round. It was connected with the acromion and sternum, just like the primi- tive bone. The power, which thus reproduces bones, is only a modification of that which unites fractures. Indeed, w hat consolidates bro- ken bones, and is known by the name of callus, presents all the characters of new bone, begins and grows in the sarnejvay, and may be impeded and retarded m its formation by the same causes. (See Callus and Fractures.) It is further highly probable, as Weidmann remarks, that the power which effects the reproduction of bones, is the same as that, which. in the sound state, nou- rishes and supports these*parts. But to what organ appertains the function of reprodu- cing bones ? Many able men have ascribed the whole work to the periosteum. (C. Havers; Du- hamel, Mem. de l' Acad, des Sciences, 1739, 1741, 1742, 1747. Fougeroux, Mem. sur les Os; Paris, 1760. Swencke , Hnrlemer Ab- handlungen 1, th. p. 39. Berlin, Osteologie. Marigues, Abhandlung von der Fatur und Erzeugung des Callus, p. 199.) Haller, ( Elem . Physiol. T. 8, p. 352.) Callisen, ( Collect . Hafn. T. 2, p. 187.) Te- non, ( Mem de VAcad. des Sciences, 1758 ,p. 415.) Bordenave, (Mem. sur les Os,p. 227) and many others, have seen a part of the new production spring up from the substance of the old bone ; a thing, says Weidmann, which one is also led to believe by the fact, that, when the whole tube of a long bone is affected with necrosis, the epiphyses which remain sound and untouched, unite and grow' to the new tube, though no peri- osteum exists in the situation of the union. Nor does Weidmann think that the speci- men of a fractured thigh, of which Blumen- bach has published an engraving, proves the contrary. (Geschichte und Berschreibung der Knocker; Gottingen, 1786, Tab. I, Jig. 1.) This preparation exhibits an union which had taken place by means of a very broa osseous ring, encompassing the ends of th fracture w hich lie far asunder. The even appears to Weidmann to have been thi result of rachitis, or lues venerea, with wdiic! the young patient, according to Blumenbac' himself, had been affected, and by whicl the nutrition of this bone had been disorder ed For, says Weidmann, in other exam pies of united fractures, the ends of the bom are so connected together by the callus, that there does not exist a single point be- tween them, where this substance is not effused, and the medullary canal itself is obstructed and filled with it. In the Journ. Comptem. du Did. des Sciences Med. T. 8, may be found some considerations, offered by Larrey, against the doctrime that the periosteum is the organ of ossification. That, however, the periosteum is fre- quently the organ of the reproduction of the bones, seems proved by the experiments of Troja, Blumenbach, Desault, and Koeh- ler, since in these the bones were invariably regenerated, though there was nothing left of the old bone that could furnish the new reproduction, except the periosteum. If we examine the new bone, at different periods of its developeinent, it appears in the earliest state in the form of a redidsh fluid, as has been observed by Duhamel. Fougeroux, Bordenave, Haller, Callisen, and others. If we also attend to the pro- gressive changes which this fluid undergoes, we cannot but believe that, as in the em- bryo, an organic and fixed arrangement of parts takes place. Indeed, it would be er- roneous to consider such fluid as destitute of organization and extravasated at random. Thin and little in quantity on its first appear- ance, its consistence and quantity afterward gradually increase (Troja, p. 42, 44,) so that what at first appeared like a liquid, soon becomes a gelatinous substance, in which are developed, especially at its inner surface and towards its lower part, bony fibres, which incessantly become more and more numerous. These fibres in a short time form little layers and cells, and extend themselves every where, so that at length all which was fluid disappears, and the new bone is produced. While young, however, it is still spongy and reddish, (Troja, p. 44;) but soon becomes denser, harder, and more solid, than that was for which it is a substi- tute, and it acquires the ordinary colour o the rest of the bones. NECROSIS. 271 The external surface of the new bone, which, during the period of its formation, was irregular, and studded with several ex- crescences of various sizes, and pierced with apertures of different dimensions, becomes in the course of time smooth and regular, especially after the expulsion of the seques- trum. The sides, or walls of the new bone which at first were of considerable thickness, in time also grow thinner. ( Truja , p. 21.) When the entire dead bony cylinder con- tinues in its cavity, the new bone is neither shorter, nor longer, than the original. But, should one of the ends of the dead tube protrude from the cavity, while by the side of the affected bone, there is not another one capable of resisting the action of the muscles, the new bone will be shortened, and undergo some change in its shape and direction. Indeed, says Weidmann, the new bone in its early state, from want of con- sistence, must yield to the efforts of the muscles. Its shape is not exactly like that of the original bone: the sides are flatter; the usual angles, depressions, and eminences are not observable, and sometimes others are formed. How admirable is the process, by which the muscles, detached from a bone affected with necrosis, have other insertions given to them, and are thus rendered capable of per- forming their functions ! (Troja, p. 27.) The periosteum, which swells as soon as the exfoliation of the old bone commences, shrinks, and is not at all thickened, when the exfoliation is finished. Troja, having destroyed the medullary structure of a long bone, found the periosteum swelled at the end of 36 hours; but he observed, that the whole, of such swelling disappeared before the 25th day. (P. 43, 67.) The periosteum, which thus survives, ad- heres to the new bone, as it did to the old one : its vessels, which are now increased in diameter, and convey a larger quantity of blood, dive into large apertures in the re- generated bone, ramify every where in its substance, and nourish it. Dr. Macartney’s observations nearly agree with those of Troja and Weidmann, respect- ing the formation of the new bone by ihe periosteum, with this difference, however, that he does not describe the original perios- teum as becoming afterward attached to the new bone, but as disappearing. Dr. Macart- ney remarks, “ that the first and most im- portant circumstance is the change, which takes place in the organization of the perios- teum ; this membrane acquires the highest degree of vascularity, becomes considerably thickened, soft, spongy, and loosely ad herent to the bone. The cellular substance, also, which is immediately connected with the periosteum, suffers a similar alteration : it puts on the appearance of being inflamed, its vessels enlarge, lymph is shed into its interstices, and it becomes consolidated with the periosteum. These changes are prepara- + orv to the absomtion of the old bone, and the secretion of the new osseous matter, and even previous to the death of the bone, which is to be removed. In one instance, I found the periosteum vascular and pulpy, when the only affection was a small abscess of the medulla, the bone still retaining its connexion with the neighbouring parts, as it readily received injection. The newly or- ganized periosteum, &c. separates entirely from the bone, after which it begins to re- move the latter by absorption and, while this is going on, its inner surface becomes covered with little eminences, resembling granulations. “ In proportion as the old bone, is removed, new osseous matter is dis- persed in the substance of the granulations, whilst they continue to grow upon the old bone, until the whole, or a part of it, is com- pletely absorbed, according to the circum- stances of the case. What remains of the investment, after the absorption of the old bone, and the formation of the osseous tube, w T hich is to replace it, degenerates, loses its vascularity, and appears like a lacerated membrane. I have never had an opportuni- ty of examining a limb, a sufficient time after the termination of the disease, to ascertain, whether the investment be at last totally ab- sorbed, but in some instances, 1 have seen very little remaining. During the progress of the disease, the thickened cellular sub- stance, which surrounded the original perios- teum, becomes gradually thinner ; its vessels diminish, and it adheres strictly to the new- formed bone, to which it ultimately serves as a periosteum.” Dr. Macartney states, that the anatomical preparations, which au- thenticate the above observations, are pre- served at St. Bartholomew’s Hospital. (See Crowther on Whitt Swelling, p. 183. Ed. 2.) Mr. Stanley, however, lately showed me in the same museum, a preparation, which tends to confirm the accuracy of Troja's account of the old periosteum becoming adherent to the new bone. In this example, the periosteum is perfectly continuous with that covering the epiphyses. If this were not the fact, w r e should have to explain iu what way the periosteum of the new bone is formed. We know that the vessels of the original periosteum enter the new bone, in order to complete its formation, and it seems more consonant with the uniform simplicity of nature’s operations, to suppose that this connexion is kept up, than that the old periosteum should be totally removed, after the production of the new bone, and another membrane of the same kind be then gene- rated. An interesting example of necrosis of the thigh-bone, published some time ago by Mr. C. Hutchison, tends also to prove, that the new osseous shell is commonly formed by the periosteum, as, in this case, the medulla- ry bags, or cells, were found completely ossified, ( Practical Obs. in Surgery , p. 135) and could not therefore be supposed to be capable of the work. Among the moderns, also; Dr. McDonald deserves to be mention- ed as one of the most distinguished advo- cates for the truth of Troia’s explanation of .272 NECROSIS. this subject. (See MDonald’s Thesis de JYecrosi ac Callo ; Edinb. 1799.) Another late writer has adduced many arguments to prove that the pulpy mass, which extends from one epiphysis to the other, and is itself at last converted into bone, is formed quite independently *>f the original bone, or the periosteum. (See R ussell's Practical Essay on Necrosis, p. 27, Edinb. 1795.) This ac- count, however, is contrary to the observa- tions of Troja, David, Weidmann, ATDouald, Macartney, and numerous other observers. Indeed, a modern author seems to think the periosteum so essential to ossification, or the production of a new bone, that he attempts to explain the cause of fractures of the patella not becoming united by a bony sub- stance, by adverting to the deficiency of periosteum upon it ; a circumstance which lie deems also a strong argument against Mr. Russells doctrine. (See Hutchison's Practical Observ. in Surgery, p. 141, 142.) These very same cases, however, fractures of the patella, do sometimes unite by bone, and, therefore, while Mr. Hutchison is urging them as facts against Mr. Russell’s opinion, Baron Larrey is actually adducing them in its support. (See Journ. Compttm. du Did. des Sciences. Med. T. 8.) The experiments of Breschet and Villerme are decidedly against the periosteum being exclusively the organ of ossification. Professor Boyer does not refer all the work of reproducing bones exclusively to the periosteum in every instance ; but joins Weidmann in believing, that what seems a new bone is sometimes only a separation and thickening of the external layers of the original bone, which have escaped destruc- tion. He notices the modifications, to which the phenomena of necrosis are sub- ject when the disorder affects the whole thickness, and the whole, or the greater pari, of the circumference of a long cylindrical bone. When the periosteum is destroyed together with the bone, and the medullary membrane, which does the office of an in- ternal periosteum, is preserved, Boyer represents the latter membrane as under- going similar changes to those which we have mentioned as taking place, under other circumstances, in the external perios- teum, and he describes it as becoming the organ by which the new bone is formed. (See Traiii des Maladies Chir. T. 3, p. 432.) But when the whole thickness and circum- ference of along bone are destroyed, together with the medullary membrane, while the periosteum survives, Boyer agrees with Troja, kc. in believing the latter membrane to be the means by which the new bone is generated. The internal surface of the new bone is lined by a new membrane, which serves as a periosteum, and is at first hardly distin- guishable. ( Troja , p. 56.) In the early state, it is soft and pulpy ; (ibid, p 22 .) but, by degrees, it grows thicker and firmer, and is at length converted into a true membrane, which sends a great number of vessels into jhe substance of the bone. When this mem- brane is torn off, the surface, which it cover- ed, is found somewhat smooth, the edges of the bony layers, and projections of the fibres being blunt and rounded The cavity of the new bone includes, and almost entirely onceals the dead fragments. Sometimes, however, the new bone forms a sort of bridge over the sequestrum, in such a manner that the cavity is open above and below, in both which situations the seques- trum can be felt. ( Hunter , in Med. Obs. and Inquiries Vol. 2, p 418.) Sometimes, it is only a narrow cross-piece, which forms the bridge retaining the seques- trum. ( Weidmann . vid Tab. 5, Fig. 1, a.) The new bone may also have an opening in it, out of which the dead portion protrudes. (lb. p 35.) Sometimes the cavity of the new bone is single ; while in other instances, there are several successive cavities in the direction of the length of the bone, with transverse interspaces between them ; or else the cavi- ties are situated laterally with respect to each other, and divided by partitions. ( Weidmann , 77*6.7, Fig 2.) These cavities are proportioned in size and shape to the fragments of dead bone, w'hich lodge in them. It occasionally hap- pens. that they open into some neighbouring joint, and bring on suppuration there : a very unfavourable complication. (Ibid.p. 34, and Tali. 6, Fig. 3; also , Boyer , Trail6 des Mai. Chi-. Tom 3 ,p. 435.) Let us next follow Weidmann, and take notice of the holes, by which the cavities, including the dead pieces of bone, open externally, which Troja denominated the large foramina, and which the preceding ex- cellent writer preferred calling the cloacae , because they serve to convey outward the matter and any separated pieces of bone. In the beginning of the disorder, they are not observable, a certain space of time appear- ing to be requisite for their formation. They are noticed in long cylindrical bones, whe- ther original, or of new production, whose cavities contain dead fragments. These openings vary in number: when the sequestrum is small, only one is found ; but, when the piece of dead bone is exten- sive, there may be two, three, or four. Weidmann never saw' more than five. But Troja met with eight. ( P . 58.) Weidmann possessed a small portion of the diploe of the os innominatum, which was affected with necrosis, and contained in a bony cavity, that had no external opening what- ever. When there are several distinct cavities iu the same bone, containing dead frag- ments, each cavity has at least one external opening. These cloacae, or apertures, are commonly situated at the lower and lateral parts of the cavities ; pass obliquely outwards; and com- municate with fistulous ulcers, which open on the surface of the skin. (David, p. 186.) Some of the cloacas, however, form uttlie middle, or (what is exceedingly rare) at the upper part of the cavities, and proceeding NECROSIS'. *2.73 outward, without any oblique track, go to the front, back, or lateral parts of the limb. They are of a round, or oval shape, or nearly so. Their usual size is such, that it will just admit a quill, and they vary very little from this dimension. They terminate internally by converging approaching edges, in the manner of a fun- nel ; while, on the contrary, the margins of their outer extremity expand. The canal between these two orifices is sometimes long, sometimes short, and in certain cases, of no extent at all. Different opinions have been broached, respecting the causes which produce the apertures in the new bone, termed by YVeid- mann the cloaca. M. David says, that the pus collecting in an eariy stage of the disease between the bone and periosteum, distends and corrodes this membrane, and that the openings which form in it become afterward a cause of fis- tulas in the new bone. (P. 186.) But it is observed by Weidmann, that this explana- tion is inadmissible, since the existence of the collection of pus, mentioned by M. Da- vid, is not proved by observation : in fact, it was never met with by Troja, Blumen- bach, Desault, Koehler, and many others, in repeated experiments made on the subject. (Troja, p. 56 and 66 ; Weidmann , p. 36.) Koehler thought he had seen the new bone itself destroyed by the pus, and cloaca thus produced. (P. 68 — 72.) YVeidman, however, deems this opinion quile as improbable as the preceding, for the fact of the surface of these bony aper- tures being always smooth, always formed in one manner, and constantly lined by the periosteum, decidedly proves that they can- not arise from erosion. Troja, in his third experiment upon the regeneration of bones, remarked, that forty- two hours after the destruction of the me- dulla, there took place, between the bone and the periosteum, an effusion of lymph, which was at first thin and little in quantity, but afterward became thicker. He noticed, in the midst of this gelatinous substance, some small spaces , where il teas deficient, and which had. instead of it, a subtile, whitish, dry in- crustation, which, though tolerably adherent , could be rubbed ojf. These small spaces, ac- cording to Troja, produce, the apertures called the cloaca. ( Troja, p. 45.) In another experiment, he had an opportu- nity of examining the above little spaces at the end of forly-eight hours ; he affirms, that they were replaced by the large aper- tures, or cloacae, of the new bone (P. 47 ;) and that such openings were invariably formed in the place of the small incrusted spaces already described. (P. 58.) As Troja took notice that no lymph was effused at these particular points, he was inclined to impute the circumstance to adefect in the os- sification, and, perhaps, to the death of some ]iartsif the periosteum. Weidmann acknow- ledges, thai the mode, in which the lorma- tion of the cloacee happens, is exceedingly obscure ; and expresses his belief, that Vot II 35 Troja’s account of it approaches the nearest to the truth. But, says he, one thing is cer- tain, namely, that these openings have no other use, but that of conveying outward the pus which collects in the cavity, and the small bony fragments, since, as soon as every atom of dead bone has passed out, they diminish, and, at length, are lotally obliterated. ( W eidmann Dt JYecrosi Ossi um , p. 36.) It is a remarkable circumstance, in the history of necrosis, that, in favourable in- stances of the disease, the inflexibility and firmness of the limb are preserved during the whole of the process, by which the new bone is formed. Consequently, the new bone must have begun to grow, and have acquired firmness before the old bone sepa- rates, «r is absorbed. Were this not the case the limb must become flexible and use- less, the moment the dead bone is removed. Another consequence of the new bone being formed, before the removal of the old one, is that the former must surround and include the latter. For, since the lifeless portion of bone completely occupies the space between the two living ends, these cannot be imme- diately connected by the new bony matter. The connexion can alone be completed by the new bone being deposited on the outside of the old one, from one end to the other, and attaching itself to the portions which still remain alive. The new bone must also be necessarily larger than the old one, because externally situated, and hence the affected limb, after the cure is complete, will always continue larger, clumsier, and less shapely than the other. The length of it, however, remains unaltered, because the old bone re- tains its attachment, while the rudiments of the new bone are lying on its outside, and connect the living ends of the old one, by an inflexible mass, equal in length to the portion which is destroyed. Thus we see, that, in the process which nature follows in the formation of the new osseous shell, the old bone serves as a mould for Ihe new one, and the first stef) of the process is to surround the old bone with an effusion of coagulating lymph. (See Russell on Necrosis, p. 2 — 7.) When the sequestrum isthrow'n off slowly, the inflammation is moderate ; but when it separates quickly, while the new bone is in a soft stale, the detachment is always preceded by severe inflammatory symptoms, and fol- lowed by a temporary loss of the natural firmness of the limb. This premature sepa- ration of the sequestrum often occurs in ne- crosis of the lower jaw, and the chin conse- quently falls down on the neck. In certain cases, the sequestrum separates at each end from the living portions of the old bone, before the new osseous shell has acquired firmness, so that the limb feels as if it were broken in two places. (Russell.) Let us next consider the states and circum- stances of necrosis, in which the art of sur- gery may be advantageously exerted in the assistance of nature, and the means which may be employed for this purpose. NECKUS1S. A common error of medical and surgical practitioners is always to impute the cure of every disease to whatever remedies happen to be employed, and successes are loo oiten boasted of, the merit of which belongs en- tirely to nature. It is, indeed, not very u»- frequent to hear remedies panegyrically spoken of, which counteract the salutary efforts of nature, who, in this case, is obliged to overcome both the disease, and the i> ra- tional treatment, which is applied to it. As Weidmann observes, this erroneous mode of considering things has happened particularly often among surgeons who have bad cases of necrosis under their care, all of whom boast of the cures which they have accom- plished, although some employed absorbent earths, others, aromatics ; some, spirituous applications ; others, balmy remedies ; some, acids; others, caustics; and some, armed with a wimble, made numerous perforations in the dead bone ; while many others rasped the part, or attacked it with the trepan, cut- ting forceps, the gouge and mallet, or even the actual cautery ; and a certain number did nothing more, than apply dry lint. Na- ture, who was favourable to all, did her ow n work in silence, whatever were the remedies employed for her assistance, whether mild and inert ; acrid and corrosive ; or hurtful and improper. We have already noticed, that a dead portion of bone separates from the living exactly in the same way, as gangrenous soil parts spontaneously drop off, without the interference of art. The separation happens precisely at the points to which death has extended ; limits, w hich are w ell understood only by nature, and of course can be mea- sured only by her. Art w ould incur great risk of either going beyond them, or else of not reaching them at all. Perhaps, it may be deemed unsafe to confide the process of separation, or exfoliation, to nature. Bui, in what other manner could it be more safely accomplished, without hemorrhage, or pain to the patient — w'itbout any risk of a recur- rence of inflammation, or of a fresh necrosis? Is there reason to fear, that when every thing is left to nature, the separation cannot be finished till after a very long period of time ? It is true, say Weidmann, that the process frequently requires a considerable time ; but, as the vitality of the bones is not possessed of much energy, and their compo- nent parts strongly cohere, slow ness is in- evitable in an operation, which depends entirely upon the vital power. What is it then which surgery can do to accelerate the process ? Will any of the above-mentioned topical applications have this effect ? They are put upon the inert surface of a dead piece of bone, in which no vital power, or action, can be again excited. When acrid, they prove irritating, inflaming, and destructive of the neighbouring flesh, without any utility — and cause pain to the patient, which is com- pensated by no good. Would the perfora- tions, recommended by Celsus,Belloste, and many others,, have the desired effect ? If, says Weidmann, they are confined to the dead hone, they cannot have more effect, than the scarifications, which were formerly practised by ignorant surgeons in cases of gangrene ; and, if they extend to the living bone, this will be injured or at least run the risk of being so. Lastly; Weidmann demands, if the separation can be accelerated by the actual cautery, which cannot act upon every point of the necrosis, and which, unless applied with the greatest precautions, will burn the subjacent parts, and bring on a new attack of inflammation, without for warding the exfoliation in the smallest de- gree ? Of what use can rasping and scraping in struments be, which act merely upon the ' dead part ? Or will the gouge, and other cutting instruments, do more good? They cannot take away the whole of the dead portion, w ithout injuring the adjacent living bone, and causing a risk of another necrosis . And, if they leave any pieces of the old dead bone behind, nature will be as long in effecting the separation of these, as she would have been in detaching the entire ne- crosis. Weidmann mentions a case, w hich occur- red in the hospital of St. Roch at Mentz. A man’s legs were seized with mortification, in consequence of exposure to cold ; the whole of the dead parts separated ; and the bones were sawn through on a level with the living flesh. A portion of the end of each bone, however, was afterward thrown oft altogether by nature, and Weidmann thence concludes, that the previous use of the saw- had been fruitless. Weidmann then cites another case of mortification of the leg and half of the thigh, which was the conse- quence of a putrid fever. The leg sloughed aw r ay, leaving the lower portion of the thigh bone uncovered and projecting. Under a tonic plan of treatment, this part of the bone spontaneously separated. As, however, a considerable quantity of integuments had been destroyed, the ulcer was slow- in heal- ing ; but, it cicatrized at last, and the young woman continued well long afterward. Weidmann has quoted the memorable case, in which Mr. Charles White first sawed oft' the upper part of a diseased humerus. (See Amputation.) As, in this instance, nature accomplished of herself the separation of another dead portion of the same bone, two months after the operation, Weidmann seems disposed to think the cure would have hap- pened equally w r ell without it. In cases of slight superficial necrosis, sur- geons have frequent opportunities of trying- every kind of topical application ; and when the cure takes place, during the use of any of them, the benefit is ascribed to whatever happens to be in use. But, says Weidmann. in numerous more serious examples of ne- crosis, itis impossible to make these applica- tions reach the whole surface of the dead bone; but, notwithstanding this circum- stance, the separation is not impeded. Some exfoliations happen, without our knowing of their occurrence, nnrl without a thought .NECROSIS 2 75 navingbeen entertained of promoting them by any vaunted applications. We even see necrosis separate, whose situation rendered them inaccessible to our remedies ; such are the necrosis, which occur within the long bones, and comprehend the whole of their cylindrical shaft or body. What surgeon shall presume to boast of his having etfected by topical applications, the separation of the whole lower ja w-b one . atiiing, w-iich nature has very frequently accomplished ? And, when, as often happens, the entire diaphysis of the thigh-bone, tibia, or other long bone, comes a. tv; or, split longitudinally, such bone loses \ half of its cylinder ; h -w is it possible for any topical applications to reach every point, at which the separation occurs ? The internal remedies, such as assafcetida, madder, sarsaparilla, hemlock, belladonna, oaopordum, lime-vvater, &c. recommended by numerous practitioners, have in reality no direct efficacy in promoting the separa- tion of necrosis : if, says Weidmann, they do any good, it can only be by their tonic and alterative qualities, or rather by keep- ing the patient amused, so as to gain the re- quisite time for the completion of the pro- cess of exfoliation. The employment of all these ineffectual means, Weidmann con- ceives, must have originated from ignorance of the process, followed by nature in separa- ting dead portions of bone, and from ascri- bring to the arterial puisations or the power of the granulations, what certainly depends upon the action of the absorbent vessels. A < aestion here naturally presents itself. — Wou J there be any utility in exciting by stimulants the action of the lymphatic ves- sels, in order to accelerate the separation, of which it is the efficient cause ? Weidmann thinks, that very beneficial effects might result from the plan. But, he asks, what means should be used for this ob- ject ? Cold ? Purgative medicines ? Repeat- ed vomits ? Squills ? Camphor r Neutral Salts ? Issues ? (Fi’d. Wrisberg, Comment , Soc. Reg. Gotl. Vol.9, p. 136, 1789.) He adds, that, perhaps, many valuable discoveries will hereafter be ma le on this subject. The reasons already detailed, and a varie- ty of experiments successfully made by Weid- mann, lead him to set it down as an esta- blished principle, that the separation of a necrosis is almost entirely the work of nature, and that surgery tan do very little in the business. Ignorance of this important fact paved the way to the wrong practice of making incisions, for the purpose of exposing the whole surface of a necrosis, immediately the existeuce of the disorder was known. As such incisions very soon closed up again, so as to leave only a small outlet for the matter, they were in many cases repeated- ly practised before the dead bone became loose. The avowed design of the incisions was to make room for the topical remedies, which w ere to render the exfoliation quicker ; but, as these remedies possess no real efficacy, it follows, that making incisions, before the dead bone is loose, only torments the patient, without producing the least benefit. The orifices of the ulcers, then, which allow the discharge to escape freely, are, says Weidmann, sufficient as long as the frag- ments of bone are not entirely detached, and. the surgeon should all this period ab- stain from the use of the knife. Although Weidmann condemnsevery mode of treatment, which is inefficacious, painful, and sometimes even hurtful, he would not hwe it supposed that he altogether rejects all assistance from medicine. On the con- trary, he approves of all those means, which are consistent, with - the views of nature, which ireally assist her. and do not tease the patient to no purpose. In short, says he, the indications are limited to removing the origi- nal cause of the disease ; to alleviating the symptoms ; to supporting the patient's strength, and improving the state of the constitution , in whatever respect it may be bad; and , lastly, removing the dead portions of bone, when they become loose. Above all things (continues this sensible practitioner) the surgeon must not regard every piece of exposed bone, as necessarily affected with necrosis, and, in consequence of such idea, have recourse to acrid, dry- ing caustic applications. Such means are not only useless, but absolutely pernicious; because they may actually cause a necrosis, which did not exist, before they were used, and which would not have taken place at all, if only mild simple dressings had been employed. VYT . the disease presents itself with vio- lent symptoms, the inflammation and fever being intense, the severity of the case is to be assuaged by low diet, antiphlogistic reme- dies, emollient applications, and venesection in moderation, the disease being one which is of long duration, and apt to wear out the patient’s strength. Here, perhaps, topical bleeding ought always to be preferred to venesection. When the necrosis has arisen, from syphilis, scrophula, or scurvy, &c. the medicines, calculated for the cure of these affections, must be exhibited, ere any fa- vourable changes can be expected in the state of the diseased bone. Lastly, it is the duty of the practitioner to extract the fragments of dead bone, in order Ihat the deficiencies produced by them may be filled up, and the ulcers of the soft parts heal. Nature, who succeeds by herself in detach- ing the dead pieces of bone, can do very little in promoting their passage outward. Frequently, indeed, she has no power at all in this process, and it is only from surgery that assistance can be derived. When a dead piece of bone is still adherent at some points, its extraction should be postponed, until it has become completely loose. If it were forcibly pulled away, there would he danger of leaving a part of it behind, which must have time to separate, ere the cure can be accomplished. But, when a fragment is entirely detached, and the orifices of the sores are sufficiently NECROSIS 276 large, it is to be taken hold of with a pair of adherent to the adjacent parts ; and, if they forceps, and extracted. When the ulcer has only a very narrow opening, suitable incisions must be practised, • fv. fsw.ilitatft th« removal of the Toosf in order to facilitate the removal of the foose dead bone. Sometimes, the dead fragment protrudes from the ulcer, and projects externally, so that, if loose, it admits of being taken hold of with the fingers, and removed. In this way, Weidmann took away a large dead piece of the humerus, which protruded near- ly two inches out of an ulcer in the middle of the arm. The patient was a young lad, 14 years of age ; and the limb concave within, convex externally, thicker, and one inch shorter than its fellow. He got quite well three weeks after the removal of the dead bone. delay too long, the patient may be irreco- verably reduced, while the new bone, on account of the hardness which it has now acquired, cannot be so easily perfora- tecf Patients are met with, who have been afflicted with necrosis several years. In such cases, great circumspection is necessa- ry, and the practitioner should carefully endeavour to ascertain, that the dead pieces of bone have not been absorbed, or come away piecemeal in the discharge, lest an useless operation should be done, as once happened in the practice of M. Bousselin. (M6m. de la Sucirte Royale de Mddecine, T. 4, />.304.) Therefore, when the disease is of long continuance ; when the discharge is much less than it v\ as at the commencement ; We have already adverted to the example, when small pieces of bone have at times recorded by Weidmann, in which a shoe- been voided ; and the sequestrum cannot maker removed by himself nearly the whole be felt with a probe; it is doubtless, says body of the tibia. " Doubtless, the projection Weidmann, most prudent to abandon all idea of the bone, and its looseness, enabled the of operating, and allow nature to finish what man to do this easily with his fingers. But, there are cases, which present more difficulty ; such arc those, in which the sequestrum is included in a cavity, either of the original, or new bone. she has so well begun. In short, when the sequestra are undergoing a gradual absorp- tion, without ever making their appearance externally, or giving any considerable dis- turbance to the constitution, or, w hen the The old surgeons were in the habit of am- dead bone is making its way outward, with putating limbs which were in this state; out occasioning urgent inconveniences ; the although instances were not wanting in their surgeon should interfere very little with the days to prove the possibility of relieving the natural progress of the case. When the disease, w ithout amputation. Thisbiamable dead bone does not tend to make its way custom of removing every limb, thus affect- through the skin, but lies quietly concealed ed, is justly exploded from modern surgery, in the new osseous shell, the occurrence of Aibucasis was the first who attempted to extensive suppurations may be prevented, cure such a case of necrosis, by the judicious employment of the knife and saw. (Lib. 2, cap. 88.) The same kind of practice wms successfully adopted in iwo instances by the celebrated Scultetus. vSee Armament Chi- rurg. Tab. 46, and Obs. 81.) This commen- dable method, however, afterward fell into disuse, until M. David, by twenty examples of success, refuted all the objections which had been urged against it. (P. 197.) Since the by occasionally applying leeches, and keep iug open a blister w iih the savine cerate, as recommended by Mr. Abernethy in his lec- tures, and Mr. Crowther, in his work on the White-Swelling. The blister will, at the same time, have great effect in promoting the absorption of the sequestrum, and, of course, in accelerating the process of cure. If the surgeon operate as soon as the se- period of this distinguished author, the prac- questrum becomes loose, he will find the tiee has been imitated by all enlightened new bone so soft, that it can be divided with surgeons, so that the case is no longer re- a knife ; a circumstance, which materially warded as a disease necessarily requiring facilitates and shortens the operation, amputation. M. Bousselin has cut out the Keeping in mind the foregoing precepts, sequestrum eight times from the tibia, and the surgeon is to begin with exposing the four times from the thigh-bone, with per- bone in which the sequestrum is contained, feet success. ( Rid J\I6m. de la Society Royale de M6decine, Tom,. 4.) The method consists in exposing the bone, and making in it an opening of sufficient size for the removal of the loose dead frag- ments. Experience has proved, not only that, When the bone lies immediately under the skin, Weidmann recommends making such incisions as will lay bare the whole of its surface, and when its situation is deeper beneath the muscles, he even sanctions cut- ting away as much of the flesh as may be necessary to allow the instruments to be patients affected with necroses, easily bear freely worked upon the bone. I cannot, this operation, but also that after its perform- ance, the ulcers commonly heal very favourably, the health becomes re establish- ed, and the functions of the part affected are hardly at all impaired. Surgeons, however, are not indiscriminately to choose any period for doing the operation. If they are too hasty, they will run a risk of finding the dead portion of bone still however, see the propriety of this advice ; exposing the wdiole surface of the bone in the first instance, before it is known whether the saw need be so extensively used as to require such a denudation, certainly appears irrational. And, as for cutting away any portions of muscle, this can be no more ne- cessary here, than it is in the operation of trephining. But it is unquestionably proper Necrosis. to make with the bistoury sufficient space for the use of whatever instrument is em- ployed for the division of the bone. Yet it is only necessary to make this exposure in the first instance in one place. The surgeon can afterward enlarge the incision or prac- tise others, as circumstances may indicate. The surface of the bone being brought into view, if the cavities, in which the dead frag- ments lodge, present apertures which are too nariow, these apertures must be rendered larger by means of small trephines, or saws constructed on the principles of those des- cribed by Mr. Hey of Leeds. The perpen- dicularly acting wheel-like saw, turned by machinery, and invented by Mr. Machell, here promises also to be of important assist- ance. It has been used by Sir Astley Coo- per, who has given an engraving of it in bis Surgical Essays. Part I. PI. 8. Fig. 7. And another saw, constructed on somewhat si- milar principles, has been employed by Graefe of Berlin with great advantage for several years. A tract, giving an account of it, was sent to me by the late Dr. Albers, a little before his death ; but as I have now lent the publication to Mr. Stanley for the purpose of assisting Mr. Evans in the con- struction of the instrument, I shall merely add, that Graefe’s saw is turned by a handle which projects horizontally from the cutting part of the instrument and that it has a frame or fulcrum, on which it works With such instruments the pieces of bone extend- ing across the above openings, and imped- ing the extraction of the sequestra, may also be removed. But when the preceding cavities are closed on every side, and it is impossible to reach into them in any other way, than through the cloacae, a trephine is to be applied, which must comprise within its circle a half of the fistulous opening. The crown of the trephine, however, must not be broader than the cavity of the bone, nor yet narrower than the sequestrum. If, after making a perforation in this man- ner, the sequestrum should be found too large to pass through the opening, a small saw must be employed for enlarging the aperture, * * When the bone is so hard and thick that it cannot be well cut with a saw, the sur- geon has the sanction of authority and ex-./ perience, for using a gouge and mallet. When the sequestrum is found to be very large, it will be necessary to expose more of the surface of the bone by incisions. In this sort of case, Weidraann recommends applyingthe trephine to the upper and lower parts of the cavity, and then cutting away the intervening portion of bone with the saw or gouge. But there can be no doubt that a more prudent way would be to goon with the enlargement of the aperture in the bone, at the place where the first perforation took place, if the sequestrum presented it- self equally well there, because, by pro- ceeding in this manner, the surgeon might discover that the dead fragment could be taken out without so great a destruction of bone as is caused in the other mode ; and, if this were not to be the case, no harm is done, as the necessary removal of bone can be continued. When the bone, which includes the se- questrum, is a new production, and the ope- ration is not too long deferred, the soft state of the bone will enable the operator to perform the needful excisions with the bistoury alone. When the sides of the cavity, in the ori- ginal bone, are thin, fragile, and pierced with numerous holes, the surgeon can break away a sufficient portion with a pair of for- ceps. When several sinuses exist in the bone, each may be dilated, in the manner which seems most advantageous. Sufficient openings having been made into the cavities including the sequestra, the next object is to extract these dead portions of bone. In accomplishing this part of the operation, Weidmann particularly ad- vises two things; first, that no piece of the sequestrum be left behind; secondly, that no injury be done to the membrane, which lines the cavity in which the dead bone is lodged. This author observes, that there are ex- amples, in which the vicinity of certain parts impedes the surgeon from making an opening in the bone, large enough for the extraction of a voluminous sequestrum in an entire state. In this circumstance, he recommends the sequestrum to be broken into pieces by any convenient means, and the fragments to be separately removed. Weidmann has recorded an extremely in- teresting case to prove how much may sometimes be effected by taking away the sequestrum. A man, 34 years of age, who had an internal necrosis of the tibia, with abscesses and cedema of the whole limb, and who Was reduced to the lowest ebb of weakness, was put under this excellent sur- geon’s care. A perforation was made with a trephine in the upper head of the tibia ; but, this opening not proving ample enough, it was enlarged with a small saw', and a gouge and mallet. The sequestrum was then extracted. The patient’s state after- ward gradually' improved, and in nine months he was completely well. It is not to be dissembled, however, that cases do exist, in which amputation affords the only chanco of saving the patient’s life. In fact, it sometimes happens, that the cavi- ties, in which the sequestra are contained, communicate with those of the neighbour- ing joints, which then become filled with matter, and caries attacks part of the bones, to which the necrosis does not extend. On some occasions, the dead pieces of bone are very numerous, and each has a sepa- rate cavity ; while, in other instances, me sequestra lie so deeply, that a passage for their extraction cannot be prudently at- tempted. Sometimes, also, a necrosis is complicated w ith another disease in its vi- cinity. Lastly, such may be the reduced state of the patient’s health, and the parti* NKCKGSIS. ::s cular condition of the necrosis itself, that the constitution cannot hold out during the whole time which would be requisite for the detachment of the sequestrum. Under circumstances like these, amputation is ne- cessary, and ought not to be delayed. For the authorities of many of the obser- vationsand cases in the foregoingarticle, and for additional information on the subject, see Albu casts, lib. 2, cap. 88. Scultelus , .firma- ment. Chir. Tab. 46, and Obs. 81. Belloste , Le Chirurgien d' Hdpital, part 1, chap 12. J. Louis Petit , Traite des Mi ladies des Os, Tom. 2, chap. 16. Monro's Works by his Son. Tenon in M6m. de l' Acad, des Sciences, 1758. Aitken, Systematic Elements of the Theory and Practice of Surgery, Edinb. 1779, p. 288. Some interesting cases and re- marks, chiefly about the question of amputa- tion, are contained in Schmucker's Vermischte Chir. Schriften. B. 1, p. 17, \c. Ed. 2. Cal- lisen, Sy sterna Chirurgice Hodiernce, Vol. 2, p. 893, Gott. 1800. C. White, Cases in Sur- gery, London, 1770, p 57, fyc. Wrisberg, Comment. Soc Reg. Gott. Vol. 9, p. 136, fyc. Boussclin, in Mem de la Society Royale de Medecine, Tom. 4. Louis, in Mem. de l' Acad, de Chirurgie, Tom. 5. Chopart, Dissert, de Necrosi Ossium, Paris, 1776. David, Obs sur une Maladie connue sous le nom de JYd- crose, Paris, 1782. Poll's Chirurgical Works, Land. 1779, Vol. 1 ,p. 32. Bloomfield's Chir. Cases and Observations, Vol. 2, p. 9. C G. Kortum, Comment, de Viiio Scrofuloso. Lem- govice, 1789, T. 2, part 3, cap. 11. Knolli, Dissert, de Carie Ossium venerea ; Lips, 1763. S.G.Rcederer Progr. de Ossium Vitiis Observa- / iones continens ; Goetling(e,\760. Lind's Trea- tise on the Scurvy, Fabre in M6m. de VAcad. de Chir. T.4,p, 91. Bonn's Thesaurus Ossium Morbos Bond, Med. Septentr. L. 2, Sect. 4. cap. 25. Ephemer. Acad. Nat. Cur. Ann. 7 el 8, obs. 4. Guerney, in M6m. de I' Acad, de Chir. Tom. 5, in 4 to. p. 355 — 368. Belmain, ibid. p. 363. Acrel, Chirurgische Vorfalle, Ucbers. Von Murray, Vol. 1. p. 194. Van Wy, Vermischte Chirurgische Schrifteh, Nu- remberg, 1786, p. 192. Trioen , Observat. Med. Chir. Fascic. L. B. 1743,/?. 46. Rei- pleinin Richter's Chirurgische Bibiiothek , T. 7 ,p 569. Henkel, ibid. T. 2, p. 42. Dus- saitssoir , ibid. T. 8, p. 71. Meckren, Obs. Med. Chir. cap. 69. Taconi De nonnullis Granii Ossiumque Fracturis, fy-c. Bunonice, 1751, p. 17 Blancard, Inst. Chir. p. 549. Duhamel, Mtim. de V fiend, des Sciences, 1741. Boehmcr, Dus. de Ossium Callo ; Lips. 1748, p. 17 and 21. C heselden, Osteographia. or Anat. of the Hu nan Bones, London. 1733, Tab. 49, Fig 4. Morand, in Pldtner's Vermis- chte Chirurgische Sdtriflen, p. 447. Ruysch , Thesaur. 10, No. 176. Duverney, Traili des Maladies des Os, p. 457, Pans, 1751. Phil. Trans. No. 312. Wedel, in Ephem. Natur. Cur. Dec. 2, Jinn. 2, p. 396. C. Ban- tus in Chir. Tract. 4, Cap. 8, p. 275. Kos- chius,in Roonhuy sen's Historische Heilkuren, B. 1, p. 217 ; Nuremberg, 1674. Hofmann, in Eph. Nat. Cur. Dec. 3, Ann. 9 el 10. p. 310. Dumcrbroeck, vid. Wolfli Obs. Chir. Med Lib. 2. Ohs. 18,/?. 212, Wright, iv Phil. Trans, abridged, Vol. 9, p. 252. Fabricius Hildanus, Obs. Chir. Cent. 4, Obs. 91. Raw Supellex Anatom. Edit.d B. S. Albino ; Ludg. Batav. 1725, p. 13. Dobyns in Cheselden's Osteographia, Tab. 49, Fig. 4. Mackenzie, in Med. Obs. and Inquiries, Vol. 2, p\ 299. Ludwig Advers Med. Prncl. Vol. 3 p 60. Bousselin, in Hist, de la Soc. Royale de Mede- cine, 1780, 1781, Paris, p. 121—297—305. Slalpart Van der Wielin Cent. 1, Obs 96. Muralto, in Schriften von der Wundarzn. Bale , 1711, Obs. 202, p. 655 De la Moite , Traite Complel de la Chirurgie, T. 4, p. 284. Ellinckhuys in Trioen s Obs. Med. ( hir.fasc . Ludg. 1743, p . 115. Ruysch Opera Omnia Anat. Med. Chir. Amst. 1721, Tom. 1, p. 94. Laing, in Med. Essays and Obs. Edinb. Vol. 1, art. 23. Johnson , ibid. Vol. 5, art. 23. Hunter, in Med. Obs. and Inquiries, Vol. 2, p. 303. Sigwart, Diss. de Carie consumptie tibice notabili jactura, Tab. 1756. T. Bartho- line. Act. Med. el Phil. Hafn. Vol. 3, Obs. 114, p. 287. Hofmann, Mantissa, Obs. Se- lect. Obs. 28. Saviard. Nouveau Recueil d'Observ. Chirurgicales, Paris, 1702, Obs. 126. Le Dran, Obs. de Chirurgie, T. 2, Obs. 104. Michael , in Richter's Bibiiothek. T.o Troja, de Novorum Ossium in integris aut maximis, ob morbos. deperdilionibus, Regent- ratione , Experimenta. Lutetice Parisiorum, 1775. Troja' s Work, though drawn up in an incorrect style, as Weidmann remarks, con- tains many highly interesting experiments. Blumenb tch, in A. G. Richter's Bibiiothek, T. 4. p. 107. Desault's Parisian Chirurg. Journal. Vol 1, p. 100, and Vol. 2, p. 199. Koehler , Experimenta circa Regeneralionem Ossium , Gott. 1786. This is a valuable work , and contains the original discovery of the re- production of medullary structure. I. V. Weidmann De Necrosi Ossium Fol. Franco- furti ad Moenum 1793 ; el de Necrosi Os- sium adnotatio ; Frank. Del. 4. This publican tiori is, perhaps, the best general account of the whole subject of necrosis. It is not only en- riched with the observations of numerous other writers on the disease, but contains the most approved theories and opinions respecting many other affections of the bones, Caries, Exfolia- tions tyc. It was a great assistance to me in the composition of the foregoing article. Con- sult also Richerand Nosogr. Chir. T. 3. p. 153, tyc. Ed. 4, Paris, 1815. Dr. Alex. tM‘ Donald’s Thesis de Necrosi ac Callo, • Edinb. 1799. Hutchison's Pract. Obs. in Surgery, p. 180, §-c. London, 1816 James ; Russell's Practical Essay on a certain Disease of the Bones , termed Necrosis, 1794. Whale - ly's Pract. Obs. oti Necrosis of the Tibia, 1815. Macartney, in Crowther's Obs. on While-Swelling, \~c. Edit, 2. Encyclopedic Mithodique, Parlie Chir. art. Necrose. Le - viilii Nouvelle Doctrine Chir. T. 4, p. 321, fyc. Paris, 1812. Larrey’s Mam. de Chirur- gie Miiitaire, T. 3, p. 367, fyc. Thomson's Lectures on Inflammation, p. 39 iymp- tomesde la Maladie VSndrienne, des diverses MSthodes de traitement, fy-c. 3m e Ed. Paris, 1812.) The reports of Dr. Odier, of Geneva, how- ever, were rather more propitious, as he says, the nitrous acid increases the efficacy of mercury, and lessens or removes the in- conveniences arising from its unskilful ad- ministration. Ruthe candidly acknowledged, that his experience had not been great enough to enable him to pronounce, what degree of confidence ought to be put in the acid as a remedy for syphilis. (Man. de M6d. Pratique ; Geneve, p. 249.) The practice of exhibiting the nitric acid for the cure of syphilitic affections was not tried in Germany so soon as in England and France. Albers, however, in 1797, gave an account of Scott’s successful experiments, and of the efficacy which they evinced in some cases seen by that gentleman in the Infirmary at Edinburgh. (Hufeland Journ. d. Prukt. Heilk. Vol.20,p. 68;) while Behn, who had visited Paris in the winters of 1797 and 1798, briefly noticed the various results of the trials, which he had seen made of this acid, in the “ Clinique de Perfectionne- ment,” for the cure of obstinate syphilitic cases. ( Erirmerun gen an Paris, zuntichst fllr Jierzte gescrieben von G. H. Pehn Erst. Heft. Berl. 1799, p. 110.) At length, in 1799, Struve, who translated Mr. Blair’s first pub- lication into German, communicated to the profession the particulars of some experi- ments made by himself with the acid; he declares, that he bad very often found it an excellent remedy for inveterate pains in the bones, and derangement of the constitution;, produced either by the syphilitic virus or the injudicious employment of mercury. How- ever, in common cases, mercury is repre- sented as the best antisypliilitic medicine. Afterward Professor Wiirzer was induced to try the nitrous acid in a case, that had re- sisted mercury for six months, the patient having got rid of some chancres and a sore throat, but being left with violent noctur- nal pains, blotches, and sores all over his body, and in a very reduced condition, with out the least appetite. Here, in 27 days the acid, together with sarsaparilla and the warm bath, not only removed all the complaints, but actually restored the patient’s original strength, and healthy appearance. In a short note annexed to this case, Hufeland gives it as his opinion, derived from experi- ence, that the nitrous acid is effectual in ob- viating the sequela? and anomalous diseases induced by lues venerea, but that it does not permanently cure the latter affection itself. (Etwas aber die Keilkraft der Salpetersatire yn venerischen Kranklieiteu, Hufel. Journ. d. Prakt. Heilk. 8 Bd. 4 St. p. 139—143.) These vague and endless contradictions induced Schmidt, an eminent professor at Vienna, to make a series of experiments with NITRIC AND NITROUS ACIDS m liie nitric acid, for the purpose of ascertain- ing its power in cases of syphilis. (See Beo- bacht, der Kaiserl. Kvnigl. Med. Chir. Josephs Akademit zu Wien. 1, Bd. Wien 1807, p. 147 — 189.) Under his directions, the acid was given in the winter of 1799 to five soldiers, affected with the venereal disease in various degrees and forms. In every one of these cases, the medicine was found efficacious ; but the degree of efficacy was remarked to vary considerably according to the nature of the constitution, and the kind of local complaints. Thus, in robust patients, mode- rate doses of the acid soon produced bene- fit . while, in weak persons, disposed to scurvy or scrofula, a larger quantity of the medicine, and more time were requisite. This asser- tion we see is exactly the reverse of what appeared to happen in the cases treated by Mr. Cruikshank. However, Professor Schmidt entertains strong doubts, whether the nitric acid is adequate to the cure of all the forms of syphilis, and he thinks, that neither this nor any similar medicines will ever supersede the necessity for mercury. Ontyd, a Dutch practitioner, approves of the use of the nitric acid, with some limita- tion : while he admits its efficacy in remo- ving local symptoms, he is strongly against its employment in cases of confirmed lues, as they used formerly to be termed. The latter assertion, I conceive, is exactly con- trary to the results of modern experience, most of these protracted bad cases being those, which are particularly benefited by this acid. (JViewve scheidekundige Bibl. te Amsterdam ; by Doll. 6de St. 1799, p. 166.) The tracts of Boetticher, (Betnerk. fiber Medi- cinal-verfass. Hospit, u. Cnrarten. ‘lies Hefr. Kdnigsb 1800, 8,) of Ritter ( Erfahr fiber die innerl u. afisserl. Anwendung d. Salpeters. Hufel. Journ. 10 B 3 St. p. 191 — 197.) and of Frankenfeld ( Hufelund's Journ. der Prakt. Heilk. 22 Bd. 4 St. p. 96 — 98) need only be specified here, as decidedly unfavourable to the character of the nitrous acid, as areme- _dy for syphilis. The following German practitioners are to be classed with the moderate approvers of the medicine, though as Holst observes, {De Acidi JYitric (Jsu Medico , p. 88 ; Christiana, 1816,) they do not appear to have made any new experiments of their own with it, viz. Munchmeyer {Comm, de Viribus Oryge- wii in procreandis et sanandis Morbis ; Goetl. 1801, p. 54:) Burdach {Hdb. d. neuest Eut- deck, in d. Heilmittellehre ; Leipz. 1806pp. 11, 12 ;) Aronsson ( Vollst. Abhdl. aller vene- rischtn Krankh. Berl. 1808, p. 211 ;) Horn \Hdb. der Prakt. Arzneymittellehre, 2/e. Aujl. Berl. 1805, p. 95 ;) Consbruch ( Taschb . d. Arzneymittellehre, 2 te. Aujl. Leipz. 1810, p. 283 ;) Toepelmann (JVeuere Erfahr. fiber zweekem. Behdl. venerisch. Schleim ausfUisse , ^c. Leipz. 1809, p. 151 ;) and Wolikopfs {Pharmac. extemp. Leipz. 1811, p. 92.) Another German author, who has entered into the present inquiry, is F. A. Waich, whose statements are very unfavourable to the use of the nitrous acid, as he absolutely denies, that it ever accomplishes a lasting cure. ( Aitsfnhrl . Darslell. d. Urs)rr. fye. d. Venerisch. Krankh. Jena, 1811, p. 197, 198.) In a periodical work, mention is made of one case, which, after resisting a long course of mercury, and also the nitric acid, was ul- timately cured by restricting the patient for a few weeks to a very reduced diet. {Hujel. Journ. d. Prakt. Heilk. 34, Bd. 2 St. p. 66.) For much of the foregoing historical ac- count, I am indebted'to Holst s Diss. de Acidi Nitrici Usu Medico, 8vo. Christ. 1816; in which an explanation of the results of fur- ther trials of the medicine in Denmark and Sweden may be perused. From these coun- tries, the reports are mostly less favourable to the reputation of the medicine, than the accounts already delivered. According to Holst the following are the chief circumstances, under which the em- ployment of nitrous, or nitric acid is gene- rally sanctioned. 1 . Where the disease is complicated with scurvy. 2. Where it is attended with scrofulous en- largement of the glands, and other strumous symptoms. I may remark, however, that these complaints are often as undefinable, as some of the forms of syphilis, and therefore tiie rule is frequently difficult of application. 3. Where the disease is accompanied with considerable debility, either brought on by mercury, or febrile indisposition. 4. Where from idiosyncrasy, mercury can- not be safely exhibited. Experience fully proves, that there are some patients, more especially females, in whom a few grains of mercury taken inwardly, or mercurial fric- tions on the most limited scale, bring on vomiting, rheumatic pains, nervous febrile symptoms, colic, spasms, severe headachy and a rapid immoderate salivation. 5. Where pregnant women are the subjects of the disease, several practitioners forbid the use of mercury, during the latter months of pregnancy. ( Bangri , Prax. Med. Haj'n. 1789, p. 570 ; Swediaur ; Aronsonn Vollst. Abhdl. aller Ven. ICrkht. Berlin, 1811, p. 211.) Holst observes, that the reason of this ad- vice is not stated, though no doubt it must proceed from an apprehension of mercury exciting a miscarriage. Mi .Pearson’s mode of exhibiting the nitrous acid has been already mentioned. Some practitioners give it as follows: 1^. Gum. Arab. 3>v. aqua* menth. |viij. acid, nitrosi, vel nitrici 3‘j- 3«ij- F. M. Of this mixture, a table spoonful is to be taken every hour mixed w ith some sweetened water. Should the acid occasion colic, or diarrhoea, its quantity must be lessened, and opium added to the mixture. As the nitrous and nitric acids decompose and destroy the teeth, some care must be taken to prevent so serious an effect. Their being properly diluted, and blended with sugar, syrup, or mucilage, will materially tend to hinder the evil. But the safest way is always to drink the mixture through a glass tube, and wash the mouth well imme- diately after every dose. Strong nitrous acid, extricated in Ore? NIT NOL 2.84 form of vapour, is often employed as a means of purifying the air of large crowded hospi- tals and sick-rooms ; a subject on which the observations of Dr. J. C. Smyth and G. de Morveau are particularly interesting. The nitrous acid is sometimes taken by accident, or design, as a poison. Here, according to the observations of Tartra Orlila, he. the best antidote is calcined magnesia, or soap. If the first of these articles be at hand, a dram of it, suspended in a glass of water, is to be instantly given, followed by copious draughts of some mucilaginous drink, the design of which is to fill the stomach, and excite it to reject the diluted poison. While the vomiting is going on, the doses of mag- nesia are to he repeated, and followed as in the first instance by draughts of linseed tea, solution of gum arable, milk, or broth. The nitrous acid has also been extensively tried as a means of curing syphilitic com- plaints, in the form of what is termed the nilro muriatic bath , of which a description will be given in speaking of the Venereal Disease. When reiterated courses of mercury in- duce dropsy, as not unfrequently happens in very impaired constitutions, Mr. Carmi- chael prescribes the nitrous acid, in as large doses as the stomach will bear, conjoined with digitalis. ( Essays on Venereal Diseases, fyc.) Taken in doses of eight, ten, or fifteen drops, two or three times a day, it is alleged to be efficacious in the cure of some erup- tive complaints, especially of the lower ex- tremities, connected with disorder of the liver. (fVihon's Pharm. Chir. p. 6.) Another well-informed writer also bears testimony to its good effects when used together with mercury, for old obstinate ulcerations of the legs, though no venereal taint can be sus- pected ; and, he says, it may be applied with benefit as a local stimulant to fetid ulcers, attended with a thin ichorous dis- charge, and in some examples of caries. In such cases 3>j- of the diluted acid is to be mixed with Jj of water. (See A. T. Thom- son's Dispensatory, p. 441, Ed. 2.) With respect to caries, in the sense of necrosis, however, the reader will understand from what is stated in the article on that subject, that it can rarely be adviseable to apply this or any other acid either to the exfoliating portion of bone or to that which is yet alive. The nitrous acid has sometimes been used for destroying warts, condylomata, and other excrescences. By Sir E. Home it is praised as a local application for certain ulcers when properly diluted. (See Ulcers.) It is likewise commended by some writers as a very useful local application in cases of hospital gangrene. And an interesting paper has been just published by Mr. R. Welban k, detailing the excellent effects of the undilu- ted nitric acid as an application to diseases which he has described under the name of sloughing phagedeena, and which he consi- ders as identical with hospital gangrene. “ If the disease be not far advanced, (says this gentleman) I at once apply the undiluted acid, after cleansing the surface with tepid water, and absorbing the moisture with lint. Where, however, there is a thick and pulpy slough, it is better to remove as much of it as possible, with forceps and scissors, before the application is made. The surrounding parts being then protected by a thick coat- ing of lard, or cerate, I proceed to press steadily, and, for some minutes, a thick pledget of lint, previously immersed in the undiluted acid on every point of the disea- sed surface, till it appears converted into a firm and dry mass. The parts may be then covered with simple dressings, and evapora- tion kept up externally by cooling lotions. An opiate is afterward given, and the eschar removed at the end of 16 or 20 hours. When there is no pain, and the subjacent parts present a florid healthy appearance, the sore may now be treated as a common wound, though stimulant dressings are generally best. Mr. Welbank uses the ceratum lapidis calaminaris, or a solution of the argentum nitratum, in the proportion of two or three gr. to an ounce of distilled water. But, if there is any recurrence of pain, whether the affection be slight or severe, and the remain- ing slough deep or superficial, Mr. Welbank advises the reapplication of the undiluted acid. (See Med. Chir. Trans. Vol. 11, p. 369.) The cases reported by this gentle- man are highly favourable to the practice which, as may be seen by reference to the article Hospital Gangrene, is not entirely new with respect to this disease, and in speaking of Mortification, I have mentioned, that it was Dr. Kirkland’s practice some- times even to dress certain sloughing disea- ses with a solution of mercury in nitrous acid. But, notwithstanding these facts, and the well-known custom of Sir Astley Cooper to apply to sloughing phagedenic ulcers the nitric acid lotion, composed of 50 drops of the acid, and a quart of distilled water, I feel that Mr. Welbank has rendered a ser- vice to the profession by drawing their attention still more particularly to the use of undiluted nitric acid in the forms of phagedeena, which he has so well descri- bed. NODE. A swelling of a bone; a thick- ening of the periosteum, .or a fascia ; or a tumour on a tendon, from a venereal cause. See Exostosis and Venereal Disease. NOLI ME TANGERE. A species of lupus, under which term Dr. Willan intend- ed to" comprise, together with the noli me tangere affecting the nose and lips, other slow tubercular affections, especially about the face, commonly ending in ragged ulcer- ations of the cheeks, forehead, eyelids, and lips, and sometimes occurring in other parts of the body, where they gradually destroy the skin and muscular parts to a considera- ble depth. ( Bateman's Synopsis of Cutane- ous Diseases, p. 296, Ed. 3.) Sir K. Home says, that the ulcers, for which he has been led to employ arsenic, are named, from (he virulence of their dis- position, noli me tangere, and are very nearly allied to cancer ; differing from it in not. contaminating the neighbouring parts by NOLI ME TANGERE. 285 absorption, but only spreading by immedi- ate contact. Ulcers of this kind differ ex- ceedingly from one another in their degree of virulence ; but they are all so far of the same nature that arsenic in general agrees with them, and puts a stop to their progress, while they are aggravated by milder dress- ings. ( Home on Ulcers , Edit. 2, p. 267.) The disease generally commences with small tubercles, which change after a time into superficial, spreading ulcerations on the alas of the nose, more or less concealed be- neath furfuraceous scabs. The whole nose is frequently destroyed by the progressive ravages of this peculiar disorder, which sometimes cannot be stopped or retarded by any treatment, external or internal. The specific ulcerations do not generally extend to the parts far within the nostrils ; but, at the time that I am writing this article, there is, under Sir L. Harvey, in St. Bartho- lomew’s Hospital, a curious example, in which the greatest part of the nose is de- stroyed and the ulceration proceeds even through the front part of the palate into the mouth. The morbid process sometimes stops for a considerable time, and then is renewed with increased violence. The following case illustrates the nature of noli me tangere, and one mode of treatment, to which it yielded. Jane Chatillon, 45 years of age, w’as attacked, in the course of Sep- tember, 1788, with an inflammation on the left ala of the nose. Some time afterward the part ulcerated, which occasioned a trou- blesome and sometimes a painful itching ; different means were unsuccessfully employ- ed, and the case remained nearly in the same situation till the month of September in the following year. At this period the ulcer spread very fast ; the_septum nasi, the muscles and cartilages of both sides were, in a short space of time, destroyed. The ulceration extended on the left -ide, along the loose edge of the upper lip. This w as the state of her case on her admission into the Hospital of St. Louis, in the month of October, 1789. A poultice moistened with aq. veg. was applied twice a day to the ulcer ; a sudorific ptisan prescribed, and a pill, composed of one grain of calomel and one grain of sulpb. aurat. anlimonii, ordered to be taken every day. From the fifth day, the inflammation lessened. No other sensible alteration took place till the 21st. The suppuration, which till this time had been black and putrid, now became w r hite and inodorous. On the 37th the discharge was trifling, and the part was dressed with pledgets dip- ped in a solution of verdigris and corrosive sublimate, in the proportion of six grains of each to a pint of water. On the 40th day, cicatrization began to take place, and was finished by the 60th. Some time before the disease was com- pletely cicatrized, an issue was made in the arm, which was healed up without any in- convenience to the patient, six months after the cure. (Parisian Chirurgical Journal, Vol. 1.) One of the best external applications to noli me tangere is the following lotion : fj ; . Kali arsenicati, gr. iv. Aq. menthae sativa?, ^iv. Spiritus vini tenuioris, ^j. Misce et cola. 1 have seen several cases in St. Bar- tholomew’s Hospital, which were either cured or seemed disposed to get well with this useful application. The solu- tion of arsenic, which Sir E. Home has always used, is made by boiling white arsenic in water for several hours, in a sand heat. When given internally, the dose is from three to ten drops ; when for external application, a dram is to be diluted with fLij. of w ater ; and this solution is gradually made stronger, as the parts become accustomed to it, till it is of double strength. However, this mode of using arsenic is by no means a well-regulated one ; and Plunket’s caustic (see Arsenic) for outward employment, i ; not nearly so neat an application as the above-mentioned lotion. At St. Bartholo- mew’s Hospital, arsenic is administered in- ternally in the following formula : Kali arsenicati, gr. ij. Aquae menthae sativae, |iv. Spiritus vin. ten. ^j. Misce et cola. Dosis 3ij. ter quotidie. ~In this way, the quantity of arsenic is nicely determined. We shall only just add, with regard to this medicine, that, both as an external application and an inward remedy, in cases of noli me tangtre , it perhaps deserves the highest rank. One scruple of the argentum nitratum, dissolved in half an ounce of distilled water, makes a very good application which, although ge- nerally inferior, in point of efficacy, to ar- senical ones, in the present disease, occa- sionally does good, when nothing else seems to produce any benefit. The above case makes us acquainted with another lotion, which deserves further trial All fluid reme- dies must be applied to the part, by dipping little bits of lint in them, placing these on the ulcerations, and covering the whole with a pledget. The ointments which seem most likely to prove useful applications to noli me ta?igere , are the unguentum hydrargyri nitrati, the unguentum picis, and unguentum sulphuris. As far as my experience extends, they are generally less efficacious than lotions in the present cases ; but, in particular instances, they prove superiorly useful, and it deserves especial notice, that surgeons can often make no progress against this inveterate disease, unless they apply a different sort of dressing every day ; sometimes a lotion ; at other times an ointment. The little ulcers may occasionally be touched with the argentum nitratum. The small furfuraceous scabs, which are continually forming on the part affected, should be softened with a little of the unguentum spermatis ceti,and removed with as much tenderness as possible. We have already remarked, that arsenic is a good medicine to be given internally, and the best mode of exhibiting it has been already explained. Another medicine, w'bieh is often useful in these cases, is what is known by the name of Plummer’s pill, or the compound calomel pill. Hydrargyri NYCTALOPIA. 1286 submuriatis, sulphuris antimonii pra?cipitati, singulorum gr xii. Guaiaci gum mi resinae, gr. xxiv. Saponis quod satis sit Misce ; fiant pilulae duodecim. Dosis una bis quotidie. — In other instances, we may try the decoctum ulmi, or sarsaparilla?, with one of the fol- lowing pills thrice a day: Hydrargyri submuriatis gr. vj. Succi spissati cicuta? 3j Misce ; fiant pilula? duodecim. The hy- drargyrus sulphuratns has occasionally been given as an alterative medicine, for the relief of noli me tangere ; with what good effect I cannot pretend to say. In three or four less severe cases of lupus tubercles on the face, which had made no progress towards ulceration, Dr. Bateman saw the solution of muriate of barytes, taken internally, materially amend the complaint. Sqmetimes, also, a separation of the diseased parts from the sound has been effected with the knife, or caustic, and the progress of the complaint been stopped. (Synopsis of Cu- taneous Diseases, p. 296, Edit 3.) NYCTALOPIA, (from vu|, night; and the eye ; or 07rra>, to see.) An affection of the sight, in which the patient is blind in the daylight, but sees very well at night Nyctalopia, visus nodurnus, or day-blind- ness, vulgarly called owl-sight, (says M. Lassus) is an affection in which the patient either cannot see at all, or sees l ut very feebly, objects, which are in the open day- light, or situations where there is a strong light ; bu\ discerns them very well, w hen they are in a darkish place, or at sunset, or in the nighttime, if not immoderately dark. (See Pathologic Chirurgicale , T. 2, p. 539, 540.) The Greek physicians are divided in their opinions concerning the now uncommon disease nyctalopia. Hippocrates expressly says, “ we call those nyctalopes who see by night.” The author of Dejin. Medic. “that they see nothing in the daytime, but have their sight by night.” On the contrary, Paulus iEgineta and \ctuarius are as explicit in asserting, that they have their sight perfect in the daytime, but are blind by night. iEtius is of the same mind, though he is thought to favour the contrary opinion, when lie says, “ they see better by night than in the day, and if the moon shines they are blind.” The author of Isagoge embraces both opinions, when he says, “ they call those nyctalopes who, in the daytime, see more obscurely, at the setting of the sun more clearly, but, when it is night, much better ; or, on the contrary, by day they see a little, but, in the evening, or at night, they., are blind.” Galen explains the word by a night blindness. Pliny, Varro, Nonius, Fes- t.us, Celsus, and other writers, give equally opposite definitions of the disorder. Dr. 'JPye questions, whether these two descrip- tions of nyctalopia, so diametrically opposite to each other, may not be reconciled by considering the disorder as an intermittent one. The difference then will only consist in the different times of the approach of the disease ; that of Hippocrates came on in the morning ; that of j^figineta, in the evening ; both were expressly periodical, and the dis* tance of time between the paroxysms, in both, was respectively the same ; a whole day, or a whole night. The various shapes, in which intermittents appear, very much favour, says Dr. Pye, such an opinion ; and the apparent success of bark in the case, which he has related, notwithstanding the unfavourable circumstances of the evacua- tions his patient laboured under, and the consequent necessity of its disuse, seem to confirm it in this gentleman’s mind. (Med. Obs. and Inq. Vol. 1.) In this work I shall follow Callisen, Rich- ter, and the best modern surgical writers, in calling day-blindness, nydalopia, and night- blindness, hemeralopia. (See Callisen , Syst. Chir. Hodiernal, Vol. 2, p. 392 and Richter , Anfangsgr. der JVundarzn. B. 3, p. 479.) Nyctalopia, in the sense of day-blindness, is a very rare disease, in comparison with hemeralopia, which is a very common disor- der in warm climates. According to Dr. Hillary, there are a people in Siam, in the East Indies, and also in Africa, w ho are all of this cat-eyed species, or subject to *he disease of being blind in the daytime, and seeing well by night. (Mod. Univ. Hist. Vol. 7.) The same author notices the general rarity of the disorder, and mentions his having met with but two examples of it. With respect to the causes of the com- plaint, Dr. Hillary observes, that it proceeds from too great a tenderness and sensibility of the iris and retina. M. Lassus thinks the causes may be of different kinds. “ If. for instance, (says he) there were a very small opacity, like a point, exactly opposite the pupil, or centre of the crystalline lens, the pupil, contracting in the open daylight, would stop the entrance of the rays of light into the eye, and a day-blindness arise, which would be diminished by the expansion of the pupil in the shade. Here, the cure would depend upon the removal of the opacity. “ Persons, wdiose pupils do not move freely, but remain much dilated, and do not sufficiently contract in light situations, are also affected with nyctalopia ; for. so large a quantity of the rays of light pass into their eyes, that it serves rather to destroy, than assist vision. Such persons see tolerably w r ell, and better than the preceding class of patients, in a darkish place, and they ought to wear green spectacles in the daytime, in order to weaken the impression of the rays of light. When a person is shut up a long while in a dark place, the pupils become habitually dilated, and ii he exposes himself suddenly and incautiously to a strong light, the eyesight may be destroyed. There are other individuals, who, from excessive sensi- bility of the iris, cannot bear much light ; their pupils instantly contract, and close, This case (continues M. Lassus) may be brought on by too great indulgence in vene- real pleasures, and in persons, who have debilitated their constitutions during their youth.” The same author mentions other cases, which seem to depend upon a species of irritability of the iris. In one instance, an 0 issue in the arm effected a cure, and he mentions the utility of blisters. He admits likewise witli Dr. Pye cases of intermittent or periodical nyctalopia, which begin regu- larly in the morning, and go off in the even- ing, the patient continuing blind, whether he keep himself in a dark or a light place. The cause of these instances, which, he ob- serves, are very uncommon, is generally seated in the primal via?, and requires eme- tics, resolvents, purgatives, and bark. (See Palhologie Chir. T 2, p. 540 — 542. Also Richter, Anfangsgr. der fVundarzn. B. 2, p. 481.) In 1787, Baron Larrey met with a case of day-blindness in an old man, one of the galley-slaves at Brest, who had been shut up incessantly for thirty-three years in a subterraneous dungeon. His long residence in darkness had had such an effect on the organs of vision, that he could only see in the dark, and was completely blind in the daytime. (See M6m. de Chir. Militaire , T. hp-6-) Nyctalopia may sometimes depend on a peculiarity in the structure and organization of the eye ; by reason of which, the quantity of light, which only suffices for vision in an eye of natural formation, proves too abun- dant for a nyctalops, and absolutely prevents him from seeing at all. We know, that in the eye there is a black substance, named the pigmentum nigrum ; one supposed use of which is to absorb the redundant rays of light, which enter the pupil. A deficiency of it might perhaps account for a nyctalops being blinded with daylight, and seeing best at night. For an account of nyctalopia, in the sense of night-blindness, refer to Hemeralopia, DEMA. (from oi4ia>, to swell.) The ancients understood, by this term, all kinds of tumours ; but it is now restricted to a swelling, arising from the effusion of a serous fluid in the cellular substance of a part ; the affection, when more extensive, and accompanied with a general dropsical tendency, becoming a medical case, and receiving the name of anasarca. An oedema- tous part is usually cold, and of a pale colour; and, as it is little, or not at all elastic, it pits, as surgeons express themselves, or, in other words it retains, for some time, the mark of the finger, after being handled, or pressed. (Edematous swellings are often connected with constitutional causes. In many cases, however, they seem to be en- tirely local affections, arising from such causes as only act upon the parts, in which the swelling is situated. Thus we observe, that after violent sprains of the wrist, or ankle-joint, the bands and feet often become (edematous ; and limbs are frequently affect- ed with oedema, in consequence of the re- turn of blood through the veins being ob structed by the pressure of tumours on them, or that of splints, bandages, &c. Pregnant women are known to be particularly subject to oedema of the legs, owing to the pressure of the gravid uterus on the iliac veins Per- sons who have been confined in bed, with fractured thighs, or legs, generally have more or less oedema in their feet and ankles, on first getting up again ; and the affection in these cases is probably quite dependent on loss of tone in the vessels of the limb. In the treatment of oedema, great attention must always be paid to the nature of the cause, in order to determine whether the disease originates from a mere local, or a eneral constitutional affection. When it epends on the pressure of a tumour on the veins, as we often see happen in cases of aneurisms, the effect cannot be got rid of till the cause is removed ; and the aneuris- mal swelling must be lessened, before the cedeinatous one can admit of the same be- neficial change. When oedema is the effect of vascular weakness in a limb, in conse- quence of sprains, contusions, &c. the best means of relief is to support the parts affect- ed, with a laced stocking or a flannel roller, while they are also to be rubbed with lini- ments, and bathed with cold spring water, till they have perfectly recovered their tone. With regard to the oedema, attendant on the advanced stage of pregnancy, a com- plete cure cannot be expected till after deli- very. The affection is generally more con- siderable in the afternoon than the morning, owing to the different effects of an erect and a recumbent position. Some relief may be obtained by the patient’s keeping as much as possible in a horizontal posture ; and, when much inconvenience and pain are felt, the parts may be fomented with any aromatic or spirituous application. Frequently, oedema is one of the symp- toms of suppuration, and, when the collec- tion of matter is very deeply situated, some- times leads to its discovery, as is exem- plified in cases of empyema. There is a species of oedema, accompanied with a degree of heat, pain, &c. in the part, and which, in short, seems combined with phlegmon In this case, cold evaporating* lotions, the application of leeches, and the exhibition of saline purgatives, are proper. An erysipelatous oedema is also met with, in which the treatment should very much re- semble what is explained in the article Erysipelas. (ESO P H A GOTO MY. (from oesophagus and 'n/uvcD, to cut ) The operation of cutting into the oesophagus, in order to take out of this tube any foreign body which lodges in it, and can. neither be extracted through the (ESOPHAGOTOMY. ■ 28 S mouth, nor pushed down into the stomach, though its removal is absolutely necessary for the preservation of the patient’s life. A substance, above a certain size, lodged in the upper part ot the oesophagus, not only obstructs deglutition, but by its pressure against the trachea, produces the most urgent symptoms of suffocation. In this circum- stance, if relief cannot be expeditiously af- forded in any other manner, and the situation of the foreign body is denoted by a prominence distinguishable in the neck , oesophagotomy should be practised without delay. How- ever, when the symptoms are pressing, yet unattended with any possibility of feeling the foreign body, either externally or with a probang, desperate as the situation of the patient may be, modern surgeons do not sanction the practice. And this difference from the opinion of the first proposers of cesophagotomy, does notarise so much from any reflections upon the greater difficulty of the operation in this circumstance, as from the consideration of its being unlikely to answer the only purpose, which makes its performance at anytime proper, viz. enabling the practitioner to extract with reasonable certainty the substance, whose continuance and pressure in the oesophagus are the imme- diate cause of the patient’s danger. Hence, when the symptoms of suffocation are ex- tremely urgent, but the foreign body produ- ces no external prominence in the neck, the surgeon should in the first instance perform tracheotomy, so as to obviate the imminent peril arising from the impeded state of respi- ration, and afterward try such measures for the removal of the substance lodged in the oesophagus as experience points out as most likely to prove successful. Though oesopha- gotomy was cursorily mentioned by Verdue in his “Pathologie Chirurgicale,” Guattani, formerly a distinguished surgeon at Rome, is entitled to the honour of having published the first valuable observations on the subject. (M6m. de l’ Acad, de Chir. T. 3, 4to.) Guatta- ni proved by experiments, that the operation might be safely performed upon dogs, which recovered after it very well, and he demon- strated on the dead body, that it was equally practicable on the human subject Nay, what is still more to the point, he brought forward two instances, in which the practice had been successfully adopted on living pa- tients. “ In May, 1738, Goursauld, a sur- geon at Coussat-Bonneval, in Limousin, was called to a man, in whose oesophagus a bone w r as lodged, an inch long and half an inch broad. Various ineffectual endeavours were made to force it down into the stomach, and, as it was perceptible on the left side of the neck , Goursauld ventured to make an incision for its extraction. The bone was thus easily ta- ken out, no bad symptoms followed and the wound healed up favourably with the aid of an uniting bandage. For six days the pa- tient was not allowed to sw r allow any kind of food, but was nourished entirely with clysters. According to Morand, a similar operation was performed, with equal suc- bv Roland, surgeon-major of the regi- ment of Mailly.” ( Mem.de VAcad. de Clive. T. 3.) Although the deep situation of the oeso- phagus, among the most important parts in the neck, makes cesophagotomy an operation of considerable delicacy in the hands even of a skilful surgeon, and one of great danger irnthose of a man, deficient in anatomical knowledge, and ignorant of the right way of proceeding, yet the propriety of perform- ing it, under the circumstances, which have bee.n specified, is universally admitted. When, however, I refer to the delicacy and difficulty of the operation, 1 arn meaning a case, in w hich a deliberate dissection is made down to (he oesophagus, without any gui- dance from the projection of the foreign body within it; a case, in which my views of the subject lead me to think, contrarily to Guattani, that the experiment would gene- rally be attended with no practical benefit ; which is also the sentiment of Baron Boyer. For, with respect to opening the oesophagus, with the view of tracing a substance in it, not externally perceptible, and either of taking hold of the same substance with forceps, or pushing it down into the stomach with other instruments, introduced through the incision, as suggested by Guattani, the chances of success must be too small to justify a practice, in which it is above all things of consequence to have the guidance afforded by the promi- nence in the throat, as a test of the foreign body being actually lodged in the oesophagus, and capable of being removed from it by tbe proposed operation. Indeed, the uncertainty of being able to reach and extract the foreign body, when its precise situation is not indi- cated by any external swelling, appears to me an objection of greater validity, than any consideration either of the increased diffi- culty of cutting into the oesophagus under these circumstances, or of the usual conse- quences of such an incision, after it has been accomplished; because the practicable na- ture of the operation, and the tendency of wounds of the oesophagus to heal favourably , when not complicated with other mischief of too serious a description, are facts proved beyond the possibility of dispute. In at- tempts at suicide and murder, and in cases of gunshot injury, the oesophagus is some- times wounded, together with other parts in the neck, and yet the patients frequently re- cover; and, when they die, their fate seems to depend rather upon other unfavourable circumstances in their cases, than upon the accidental injury of the gullet. The cures of wound? of the neck, involving the latter tube, as well as the trachea, are reported by numerous writers, B. Bell, Desault, Bohnius, &c. and some have fallen under my own observation. If it w'erc necessary to sub- stantiate this point further, I might cite the instance, recorded on the authority of Dr. James Johnson, where a man recovered after the larynx had been Completely severed between the thyroid and cricoid cartilages, and one half of the calibre of the oesophagus divided. (See llenncn's Military Surgery , p 301, Ed. 2.) But, supposing a wound of the (ESOPHAGUS.. 289 oesophagus, abstractedly considered, were more dangerous, than it really is, the ques- tion of the propriety of oesophagotomy would npt be materially affected by it, be- cause the operation is never recommended, except as a matter of necessity, and without which the patient would have no chance of preservation. As the oesophagus does not descend ex- actly in a straight line, between the. trachea and vertebra;, but inclines rather to the left side of the spine, Guattani directs the left side of the neck to be preferred for the per- formance of oesophagotomy. But, Boyer has justly remarked, that as the operation should never be attempted, unless there be projection of the foreign body, the place for the incision is always to be determined by the situation of the projection, the left side being chosen only when the prominence is either most distinguishable there, or at all events not less, than on the opposite side of the neck. (Traiti desMal. Chir. T. 7 .p. 192.) The parts, which cover the oesophagus, from the middle and external part uf the neck to the upper part of the sternum, are the skin, fat, cellular substance, muscles pro- ceeding front the sternum to the larynx, the thyroid gland, the thyroid arteries and veins, the trachea, the recurrent nerve, &.c. Guat- tani, who preferred the left side of the neck, recommended the following mode of opera- ting. The patient is to sit on a chair, with his bead inclined backward, and steadily sup- ported by an assistant. The skin having been pinched up into a transverse fold, an incision is to be made in the integuments from the upper part of the sternum. The cellular substance, between the sterno-hyoi- deus and sterno-thyroideus muscles and trachea, is next to be divided. With two blunt hooks, the lips of the wound are to be kept open ; and, on separating the cellular substance at the side of the trachea with the aid of the finger and a few strokes of the knife, the oesophagus will be seen. The lower part of this tube is then to be opened, and the wound in it enlarged with a pair of curved blunt-pointed scissors, a director being employed, if any difficulty arise. With a small pair of curved forceps, similar to those used for the extraction of polypi, the foreign body may then be removed. According to Guattani, the wound will serve for the ex- traction of the foreign body, whether this be situated above, or below it, and he asserts, that the opening will even be useful, when the extraneous substance bas passed so far down, that it cannot be taken out, as it can now be easily pushed into the stomach. Guattani lays great stress ou the usefulness of en- deavouring to unite the wound, and adverts to his experiments, proving that, in animals, wounds of the oesophagus heal very favoura- bly. If, says he, the vein, which brings back the blood from the inferior parts of the thyroid gland, and runs into the subcla- vian, happen to be cut, the hemorrhage may be stopped with a dossil of lint held upon the aperture in the vein during the operation, and afterward if the bleeding continue, Vm„ IT. B7 compression, or a ligature, is to be employed. The recurrent nerve, if at all likely to be touched with the knife, is to he cautiously drawn a little out of the way with the blunt tenaculum. Guattani also particularly insists upon opening the oesophagus as near as pos- sible to the trachea, especially at its upper part, where the artery, which goes from the subclavian to the thyroid gland, sometimes runs. When the foreign body requires an. ample opening, and particularly when the thyroid gland is enlarged, Guattani approves of separating this part a little from the side of the trachea. (See Mini- de I'Acad. Chir- T. 3, 4fo.) There can be no doubt, that Guattani’s di- rections for finding the oesophagus are very good ; but his chief defect is representing the place for the incision as beiugalways the same, whereas it ought to be partly regulated by the situation of the foreign body itself. However, his advice to make the incisions close to the trachea -appears to me more ju- dicious, than that recently delivered by Boyer, who directs them to lie made through the cellular substance between the sterno- byoideus and sterno-thyroideus muscles, and the omo-hyoideus, (see Traite des Mai. Chir. T. 7, p. 193, 8 vo. Paris, 1821,) in which method, he quits the trachea, which is the best guide to the oesophagus, and approaches unnecessarily the large blood-vessels of the neck. Yet, I agree with Boyer, respecting the general impro- priety of attempting oesophagotomy, when the situation of the foreign body is not indi- cated by any prominence in the neck, and the prudence of determining the place of the incision in a great measure by such pro- jection. Boyer also cautions the operator to let his incisions always be made in such manner, as to leave unhurt the trachea and recurrent nerve at the inner edge of the wound ; the carotid and internal jugular vein at its outer edge ; the superior thyroideal vessels, above ; and the inferior ones, below. With this view, the cellular substance is to be slowly divided layer by layer, and the blood repeatedly absorbed with a sponge ; but, if any vessel bleed freely, it is to be immediately tied. After the operation, an elastic gum ca- theter should be passed from one of the nos- trils down the pharynx and oesophagus, by which means, the requisite food and medi- cines may be injected iuto the stomach, without any risk of their passing through the incision, and retarding the cure. But, a still stronger motive for this practice is the avoidance of the convulsive action of the muscles in deglutition ; a source^ of very hurtful disturbance to the parts. Before the advantages of this contrivance were duly appreciated, the patient, for the first week, was allowed to swallow scarcely any thing, and was kept alive with broths injected up the rectum. (ESOPHAGUS, Foreign bodies in the . There are few situations, in which foreign bodies lodge more frequently, than in the oesophagus ; a fact, explicable bv the eon- (ESOPHAGUS. sissr federation of Hie iunclion of this tube, the Nearness of part of which to the windpipe at the same time accounts for the frequent danger of suffocation, when a substance, above a certain size, is lodged in it. The lodgment often takes place at the lower part of the pharynx, or beginning of the oeso- phagus, and sometimes just above the dia- phragm; hut very rarely in the intervening portion cm i hat canal. Foreign bodies liable to lodge in the oeso- phagus, arc not only articles of food, such as pieces of crust, or meat imperfectly chewed, the yolk of an egg, boiled very hard, and not masticated, a chesnut, or small apple, &c. ; but also various substances, which are accidentally swallowed either alone, or together with the food, such as pieces of bone, stones, pins, needles, buttons, pieces of money, knives, forks, scissors, spoons, keys, fcc. - These latter articles, by lodging in the pharynx, or oesophagus, may occasion very bad and fatal symptoms, and, if forced down into the stomach, may pro- duce effects of a not less serious description. Hence, an immediate attempt should always be made to extract them. For this purpose, the lingers may be employed, and, if they will not reach far enough, a pair of long curved forceps should be used. But, no instrument seems better calculated for cases, in which the body lodged in the oesophagus 13 not too wide, than the urethra-forceps, invented by Mr. Weiss, of the Strand, and used by Sir Astley Cooper for the re- moval of calculi under a certain size, from the bladder. (See Med. Chir. Trans. Vol. 31.) Nooses of wire, and bunches of thread with a multitude of nooses, fastened upon the end of a probang, and a piece of sponge fixed on the extremity of the same instru- ment, or on that of the strong wire stilet of a long elastic gum-catheter, and various other contrivances have been made with the view of extracting different articles from the oeso- phagus. The hunch of thread seems well calculated for catching hold of small sub- stances, like fish-bones, needles, &,c. ; and the sponge, when expanded with moisture and withdrawn, will sometimes bring up ar- ticles, which on its introduction, it bed passed in its dry and diminished state. When the stomach is full, the excitement of vomiting has sometimes answered ; but, if the foreign body be sharp and pointed, the method is not free from danger, and, instead of relieving the patient, may put him to great pain, and bring on violent inflammation of the passage, and the most distressing symp- toms. When the substances are not of a very hurtful kind, and cannot be extracted, they must be pushed down into the stomach with a large bougie, or a whalebone prohang, fifteen or sixteen inches long, and on the end of which a piece of line sponge is securely fastened. But such practice is not ndviseabJe, when the foreign bodies have a sharp, point- ed form, so as to be likely to prove n source of at least equal danger and suffering, if placed in contact, willr the inner surface of the stomach. Experience proves, that hardy angular substances, and pointed bodies, like nails, pins, needles, &c. which surgeons have not ventured, or not been ahle^to force down into the stomach, have often made their way, after a time, to the surface of the body, where an abscess has formed, out of which they have been discharged. When very hard, irritating bodies have either passed of themselves, or been pushed with a prohang into the stomach, their ill effects should be counteracted, and then- passage through the bowels promoted, with mucilaginous draughts, containing the oleum amygdalarum, or oleum ricine. When the substances, lodged in the oesophagus, can neither be extracted, nor pushed down into the stomach, if respiration be not danger ously obstructed, and liquids can yet be swallowed, the wisest plan is to avoid irrita- ting the passage with the further use of in- struments, and leave the case to nature, that is to say, as far as manual interference is concerned ; for, bleeding, and macilaginous oily draughts, may be in some cases useful. But, when the lodgment of a foreign body in the oesophagus dangerously obstructs re- spiration, aud the substance itself can be felt externally, the patient would perish, if some means of facilitating the breathing were not immediately adopted ; and, under these circumstances, perhaps, the most pru- dent plan would be to make an opening in the trachea. (See Bronchotomy.) The sub- sequent treatment, with reference to the foreign body itself might be determined by the circumstances of the case. In this part of surgery, one fact deserves to be particularly remembered, which is, that after a sharp, hard substance has been either ejected, orpropelled into the stomach b} 7 nature, or art, the same painful sensations in the throat frequently continue a certain time afterward, which were experienced while the foreign body was actually lodged in the passage. These sensations, however, are only owing to the manner, in which the oesophagus has been irritated, and, conse- quently, would he seriously aggravated by the further unnecessary introduction of pro- bangs. and other instruments. There may be cases, in which the patient would lose his life by suffocation, if a foreign body of considerable size were not taken out of the oesophagus, so as to remove the compression of the iracbea. Here, if it could neither be extracted, nor pushed into the stomach by common means, and its situation were indicated by any hardness, or prominence in the neck, an operation would be necessary for its removal. (See (Esopfia - gotomy.) A foreign body, not large enough to cause danger ot suffocation by pressure on the trachea, may yet bring on fatal symptoms, as is exemplified in a case, which fell under the notice of Guattani. As a man was throw- ing up a boiled chesnut in the air, and catch- ing it in his mouth, it passed down his throat;, cud he was immediately seized with a difli- c ul tv of swallowing, and scut, to the ho.- pda! i (ESOPHAGUS. 29 i However, as lie breathed and spoke with facility, and had vomited since the accident, which happened when he was tipsy, the story of his having swallowed the chesnut was disbelieved. His symptoms grew worse, and he died on the 19th day. Guattani made an incision in the left side of the neck, below the larynx and thyroid gland, which was considerably swelled, and soon came to a large abscess, formed around the portion of the oesophagus enclosing the chesnut. When the extraneous body is sharp and pointed, so as to stick in the mucous mem- brane of the passage, and it cannot be removed, nature will sometimes expel it herself, without any dangerous symptoms being the consequence. The foreign body is gradually loosened by ulceration, and is then either ejected by vomiting, or descends into the stomach, whence it is voided either through the bowels with the feces, or, as is more common, by making its way through some part of the alimentary canal, and approaching the surface of the body, where an abscess forms, out of which it is discharged. In other instances, foreign bodies, like pins and needles, which cannot be removed, pierce the oesophagus itself, gradually pass completely out of this canal, and afterward travel to remote parts of the body, without exciting much inconvenience, until, perhaps, at the end of some years, they come near the surface of the body, in a very remote situa- tion from the throat ; and an abscess is pro- duced, in which they are unexpectedly found. However, this transport of sharp-pointed substances from one part of the body to another, which is effected by a process, in which the absorbents have a principal share in the work, is not conducted in every instance with so little disturbance, and, when foreign bodies of this description come into contact with particular organs, symptoms of a dangerous and fatal kind may be excited. The great art of passing any instrument down the oesophagus, for surgical purposes, consists in putting its extremity at once directly against the posterior part of the pharynx, and keeping it closely against the vertebrae so as to avoid touching the epiglottis. The knowledge of this circumstance will be found extremely useful in passing probangs and bougies. When elastic gum-catheters are intended to be left in the passage, they are introduced down the pharynx from one of the nostrils, and, being secured, they serve for the conveyance of liquid food and medicines into the stomach with great ad- vantage, in many cases, either where the patient cannot swallow at all, or where the disturbance of swallowing would be attend- ed with considerable harm. When, however, the plan is not to leave the instruments introduced, as Boyer observes, they may be passed through the mouth. (ESOPHAGUS, Strictures, and other Dis- eases of the. Properly speaking, a difficulty, or impossibility, of swallowing should not be regarded as a disease itself; but only as a symptom of different affections, to which the organs of deglutition are liable, or of other diseases, which affect parts in the vicinity of the pharynx and oesophagus. The object of the present article is not the consideration of all the diseases, which may produce dyspha- gia, as a symptom, but chielly to notice this effect, as depending upon spasm, paralysis, or some morbid change of structure affecting the pharynx or oesophagus. Spasmodic dysphagia, as Baron Boyer has remarked, principally occurs in nervous in- dividuals, hysterical females, and hypochon- driacal men. It is sometimes an attendant on fevers ; it is declared to be constant in hydro- phobia, and epilepsy, and occasionally pre- sent in particular forms of mania. ( TraiU deS Mai. Chir T.7,p. 151.) However, with re- spect to hydrophobia, the foregoing assertion should be received with some qualification, for reasons so fully detailed in another part of this work (see Hydrophobia,) that it is unnecessary here to dwell upon the subject.. Spasmodic dysphagia is said also to be some-*, times a consequence of taking cold drink, after a violent lit of anger; of strong im- pressions on the imagination ; of worms in the stomach, &.c. When the spasm is situated in the pharynx and upper part of the oesophagus, and is considerable, neither solids nor liquids can be swallowed, and the patient has great pain and a sense of constriction in his throat... When he tries to swallow any thing soft, or even fluid, he is seized with acute pain, insuf- ferable nausea, and violent agitation of the whole frame. In this case, the spasm is never restricted to the pharynx and upper portion of the oesophagus, but extends to other organs, the inability of swallowing coming on in the midst of numerous other spasmodic symptoms, exceedingly compli- cated, and sometimes of a very alarming nature. When it is the middle, or lower, part of the oesophagus, which is concerned, as is frequently the case in hysterical women . the food passes through the pharynx and unaffected portion of the oesophagus with tolerable facility ; but, as soon as it reaches the seat of the spasm, it is either stopped, or descends further with great difficulty and effort. Liquids, especially when warm, and swallowed slowly in small quantities at a time, usually pass down with more ease, than solid substances. When the matterto be con- veyed into tbe stomach reaches the point of obstruction, the generality of patients are attacked, with pain extending along the spine between the shoulders, and sometimes- shooting to the stomach, which is consider- ably disturbed, and often discharges jis con- tents. In some cases, however, no sucti pain is experienced, and whatever the pa- tients try to convey into their stomachs regurgitates quietly into their mouths. Al- though spasmodic dysphagia is mostly com- plicated with other marks of disorder of the nervous system, it is sometimes unattended with any particular impairment of the health. {Boyer, T. 7, p. 152.) As the treatment of spasmodic affection's of the pharynx and oesophagus belongs rat her 292 OESOPHAGUS. to the physician than the surgeon, [ shall be very brief on the subject. This removal of the cause of the infirmity, that is to say, of the particular state of the mind, or con- stitution, giving rise to the spasm, is the principal thing, at which the practitioner should first aim. Thus, Boyer cured an hysterical woman of a difficulty and dread of swallowing solid food attending her, at her meals twice every day for a month, and gradually convincing her of the absurdity of her apprehension of being suffocated by at- tempting to swallow solid aliment. (Vol. cit.p. 154.) Sauvages makes mention of an hysterical female, whose difficulty of swal- lowing was cured by a regimen consisting of regular exercise, cold bathing, and milk- diet. The most successful remedies, how- ever, are said to have been camphor in large doses, and opium taken in draughts, or pills, or administered in clysters; blisters and cupping-glasses applied to the nape of the neck, or to the epigastrium. Anodyne embrocations are also stated to have been useful. At the present day, the common idea, that many anomalous affections depend upon disorder of the liver and digestive or- gans, leads to the frequent employment of the compound calomel pill, and decoct, ■sarsaparilla, with draughts of senna, rhubarb, and gentian pro re nala. Dysphagia may originate from a weak- ened, or paralytic state of the muscular fibres, which enter into the structure of the pharynx and oesophagus. The affection may be either symptomatic, or idiopathic. The first case frequently occurs in febrile dis- eases, and is generally set down by writers, as a very unfavourable omen. The idio- pathic form of the complaint may be complete, or incomplete, and is chiefly seen in persons of advanced age, though occasionally the patients are young and in the prime of life. The causes may be said to be little, or not at all understood, and the only remark, which can be safely made re- specting them, is, that they are usually con- nected with constitutional derangement. With regard to the symptoms of paralysis of the oesophagus, when the disorder is com- plete, deglutition is absolutely prevented, and, if the patient tries to swallow, the food lodges in the pharynx, and sometimes produces violent fils of coughing. Some pa- tients eat solid substances with moderate facility ; but, find more or less difficulty in taking liquids. Others can swallow hastily a large quantity of fluid at a time, yet, cannot drink slowly and a little at once. Morgagni relates an instance of still greater singularity, which was an ability to sw r allow all kinds of food very well, except the last mouthful, which always remained in the oesophagus until the next repast. ( DeSed . et Caus. J\1orb. Epist. 28, art. 14.) In cases of dysphagia from paralysis the patient suffers no pain, nor sense of choking ; if the neck be examined, no hardness nor swelling can be felt ; and a probang descends down the gullet without the slightest impediment. (Boyer, T.7,p. 158.) In its duration and termination, dysphagia from paralysis presents considerable variety the complete paralysis sometimes proves ra- pidly fatal, not however, as l conceive, on account of the affection of the oesophagus alone, but other complications, and the exhaustion arising from inadequate nutrition. Thus, Tulpius relates an instance, in which a woman died on the seventh day from the commencement of the inability to swallow, notwithstanding every endeavour was made to support her with nourishment thrown up the rectum, which was the only thing that could be done, as she would not allow a tube to be passed down the oesophagus. In other cases the patients live a considerable time, and afterward perfectly recover, and this sometimes under the disadvantage of having been entirely supported for several weeks with broth-clysters, as we find exemplified in a case recorded by Ramazzini. Certain examples are also reported, in which the patients had their food forced into the stomach by means of probangs, for years, and either ultimately recovered their power of swallowing, or in this manner prolonged their days, without any cure taking place. (Stalpart van der Wiel, Vol. 2, Obs. 28 ; Willis , Pharrti. Rat. Sect. 2, cap. 1 ,p. 45.) Paralysis of the oesophagus is to be treated on the same principles, as other paralytic affections ; a subject, which I shall not be expected to discuss ; but, it is of importance that practitioners recollect, in these cases, the very essential service derived from the use of elastic gum-catheters, with which the requisite food and medicines may be in- jected into the stomach. Dysphagia from organic disease, or mor- bid change of structure, is the most frequent case, and generally the most difficult of cure. In dissections, the parietes of the oesophagus are often found considerably thickened, indurated, and scirrhous, or sometimes almost cartilaginous, and even ossified. The parts, where the pharynx terminates in the (Esophagus, and where the latter tube joins the stomach, are occasionally converted into thick scirrhous rings with or without ulceration, exactly in the same manner as the pylorus. But, such diseases are not re- stricted to those parts of the (esophagus, but sometimes occupy other points of the pas- sage. However, the organic disease, producing a difficulty, or impossibility of deglutition, is not always situated in the coats of the (Esophagus itself ; for the parts, surrounding this canal, are subject to various diseases, which may have the same effect. Thus, dysphagia may depend upon enlarge- ment of the thyroid gland ; tumours formed between the trachea and oesophagus, or at some other point near the latter tube ; swell- ing and induration of ^thc thymus gland ; aneurism of the aorta ; enormous enlarge- ment of the liver ; and diseased lymphatic glands in the vicinity of that portion of the oesophagus, which is covered by the perito- neum, and the largest of which glands are situated near the fifth dorsal vertebra?, just at the point where the oesophagus inclines* (ESOPHAGUS 29.3 little to the right side to make way for the aorta. (Boyer, T.7,p. 162.) This last author sets down every case of dysphagia, depending upon organic disease of the oesophagus, as incurable ; and with respect to the cure of other examples, in which that tube is compressed by swellings in its vicinity, as these are almost always beyond the power of medicine and surgery, the prognosis is nearly as unfavourable, as where there is a change of structure in the oesophagus itself. There are no unequivocal symptoms, by which a case of dysphagia from enlargement of glands in the vicinity of the oesophagus can be known from seve- ral other forms of the complaint. Hence, it is difficultto estimate the correctness of certain cases, recorded by Ruyscb (Advers. Anat. Med. Chir. Dec. 1, art. 10, p. 24.) anti Haller ( Opuscul . Pathol. Obs. 78.) where .dysphagia, stated to have been produced by enlarged lymphatic glands, was cured by mercurial frictions, or pills composed of calomel, aloes, and camphor. As Boyer justly remarks, these accounts of the nature of the diseases, thus cured, are the more doubtful, inasmuch as the resolution of chronic swellings of lymphatic glands, even when externally situ- ated, is very difficult, and frequently imprac- ticable, notwithstanding the use of topical applications may here be combined with the exhibition of internal medicines (T.7,p. 169.) However, dismissing the question, whether the cases really arose rrom the pressure of enlarged lymphatic glands, or not, the facts ot the cures having taken place, under the use of mercurial medicines, are of themselves interesting. Several wri- ters consider, that there is a great analogy between certain forms of constriction of the oesophagus, and strictures of the urethra, and Mauchart recommended the two diseases to be treated, on the same principles, u it h bou- gies, and elastic gum-catheters. Baron Boyer, however, represents this doctrine as com- pletely erroneous, declaring that the affec- tion of the oesophagus is of the nature of scirrhus, and absolutely incurable. He relates one case, in which a woman’s life was prolonged by the. use of an elastic gum- catheter, though it proved of no service as a means of permanently dilating the diseased part ; and, notwithstanding nourishing li- quids were plentifully injected into the stomach, the patient suffered a good deal from hunger, and died exhausted about three years after the beginning of the disorder. This case, however, cannot be received, as a proof of the inefficacy of bougies for what is commonly implied by a stricture of the oesophagus, because the nature of the disease was not ascertained by an in pection of the oesophagus after death, and the case might have depended upon some organic disease either of this tube, or the parts in its vicinity not classed by the generality of modern writers with strictures of the passage. The following are some of Sir Everard Home’s sentiments, respecting these last cases. As the oesophagus is required to be wider at one time, and narrower at another, in or- der to be fitted for conveying the different kinds of food into the stomach, it is nearly under the same circumstances, with respect to the formation of stricture, as the urethra. For obvious reasons, strictures of the oeso- phagus are much less frequent than those of the urethra. However, they are by no means uncommon, and produce symptoms even much more distressing and dangerous, than those, which ordinarily arise from ana- logous obstructions in the passage for the urine. Of course, the most remarkable symptom of a stricture in the oesophagus is the diffi- culty of swallowing, which must be greater or less, according as the obstruction is more or less complete. Sometimes no solid food whatever can pass down into the stomach, and fluids can only descend with great diffi- culty, and in very small quantities. This is, in some instances, attended with considera- ble pain, which extends along the fauces to the basis of the skull, and through the eusta- chian tube to the ear. The pain sometimes returns at intervals, and lasts a considerable time, even when no effort is made to swal- low. If a bougie ot proper size be intro- duced down the pharynx, it will often be stopped by the stricture just behind the thyroid, or cricoid cartilage; for from Sir Everard Home's remarks, it appears that the obstruction is generally as high up as this situation. However, there are other cases, in which the obstruction is only of a spas- modic nature, and in these a bougie may be passed quite own. It is curious, that stric- tures high up in the cesophagus, often occa- sion ulceration in this tube very low down towards the stomach, just as strictures in the urethra occasion ulceration in that pas- sage towards the bladder. This is most apt to occur, when strictures of (he oesophagus have been of long continuance, and may arise from the efforts in retching, which frequently come on, and must strain the parts already deprived of their natural actions, and of the benefit of the secretions, with w hich they are lubricated in a healthy state. When such ulceration takes place, the characters of the original disease are lost ; and when the ulceration extends up- wards, the stricture itself may be destroyed. A bougie, introduced under such circum- stances, will, in general, have its point en- tangled in the ulcer ; and when so skilfully directed as to go down into the oesophagus, it will meet with a difficulty while it is pass- ing .the commencement ol the ulcerated part of the oesophagus, and ano ! her impedi- ment where it leaves the ulcer, and enters the sound portion ot the oesophagus below. These two resistances may lead to the sup- position, that there are two strictures, while in fact there is not one, only ulceration as above described. Strictures in the oesophagus are sometimes so complete, that swallowing even fluids is utterly prevented ; the patient is obliged to have nil* nourishment injected infra anum , OLE 294 CES.O and in general, soon perishes in a most ema- ciated condition. Though any part of the oesophagus is liable to the kind of contractions forming strictures, the part immediately behind the cricoid cartilage, where the pharynx ends, and the oesophagus begins, is the most fre- quent seat of the obstruction. Those which are situated further down do not so easily admit of being examined, and relieved by any surgical operation. Strictures of the oesophagus occupy very little extent of the passage, consist of a transverse fold of the internal membrane, and are attended with little thickening of the adjacent parts. These latter circumstances are such as ren- der the disease capable of receiving relief either from simple or armed bougies. There are two other diseases of the oeso- phagus, which have symptoms similar to those of strictures. One is a thickening of the coats of the oesophagus, which extends to the surrounding parts, and generally ends in a cancer, or an incurable disease. The other affection is an ulcer of the lining of the passage, commonly situated a little below the seat of the stricture, on the hack part of the tube. In the early stale, these diseases can only be distinguished from a stricture, by an examination with a bougie; afterward their nature becomes clear enough from other symptoms which arise. Strictures also take place more commonly in young subjects ; the other two diseases in the more advanced periods of life. Sir E. Horne has found, that a bougie can be more easily introduced into the cesqpha- gus, when the tongue is brought forwards out of the mouth. This gentleman remarks, that when a bougie is passed, with a view of learning the nature of the case, if it passes down to the distance of eight inches, mea- suring from the cutting edge of the front teeth in the upper jaw, its extremity has gone beyond the usual seat of stricture. If it he withdrawn without any resistance, the aperture in the oesophagus must then be lar- ger than the bougie employed. But if the bougie stops at the distance of six inches and a half, or even lower, it must be re- tained there with a uniform pressure for halt a minute, so as to receive on its point an impression of the surface by which it was opposed. If the end of the bougie retains its natural form, or nearly so, and there is an indentation on one side of it, or all round it, the surgeon may conclude there is a stricture. On the other hand, should the bougie descend without impediment, as far as seven inches and a half, and, when with- drawn, the surface of its point appear irre- gular, and jagged, the disease is an ulcer on the posterior part of the oesophagus. The mode of treatment adopted by Sir E. Home, consists either in passing a com- mon bougie occasionally through the stric- ture, and employing one of a larger size, in proportion as the dilatation oT the obstruc- tion is effected ; or else in introducing an armed bougie at convenient intervals. The \ views, which I take of the disease,- would lead me to prefer giving a full and fair tria. to the employment of elastic gum-cathe- ters. Consult Practical Observations on the. Treatment of Strictures in the Urethra and (Esophagus, 3 Vols. Edit. 3, 1805. Vol. 2, 1803, and Vol. 3, 1821, by Sir E. Home , Ph.H.Beuttelde Struma (Esophagi ; hujusque coalitu dijfficili ac abolitce deglulitionis Causis: (in Haller's Disp. Chir. 2, 395,) Tubing. 1742, Mauchart de Struma (Esophagi , Tu- bing. 1742. J. Warner, Cases in Surgery , p. 130, Ed. 4 F. A. J. Zinckernagel, de Clyste- rum JYutrienlum Antiquit ate, el Usu, ( Trilleri Opusc. 1,399.) A. Vater , el F. A. Zincker- nagel de Deglutitionis difficilis et imp edit is, causis abditis : (Halleri Disp. ad Morb. 1, 577.) E. F. Bulisius de Fame lethali ex callosa oris ventriculi anguslia. J. M. Ec - cardus , dc his qui dm vivunt sine alimento, 4 to. Kilice Holsat. 1711. Boyer Trail6 de Mai. Chir. T 7, 8 vo. Paris, 1821. OLEUM CAMPHORATUM. ft. Olei oliv®. Jb.i- Camphor® ^iv. Misce ut solva- tur camphora. Sometimes employed for promoting the suppuration of indolent, particularly scrofulous swellings, which are to be rubbed with it once, twice, or thrice a day according to circumstances. OLEUM LINI. In surgery, linseed oil is sometimes used as an application to hums, either alone, or mixed with an equal quan- tity of the liquor calcis. It has also been applied to cancerous ulcers. 1 OLEUM ORIGAMI. The oil of marjoram is often used for dispersing ganglions : the tumours are to be rubbed with it two or three times a day. OLEUM PALMiE CAMPHORATUM. ft. Camphor® |ij. Olei palm® jftj. The camphor is to be reduced to powder, and the palm oil, being melted, and suffered to be- come almost cold, is to be mixed with it in a mortar. This application is a mild topical stimulant ; and has been used for promoting indolent suppurations, especially those of a scrofulous nature, which take place under the jaw, and are attended with a good deal of chronic induration. OLEUM RICIJNI. In surgical cases, re- quiring the bowels to be opened with the slightest degree of irritation possible, the oleiim ricini is the best and safest medicine. The usual dose is one large table-spoonful, which must be repeated every two or three hours, till the desired effect is produced. OLEUM TERKBINTHINAT. Oil of tur- pentine is employed externally as a stimula- ting liniment and a styptic. In the article Liniment may be seen some formul®, in which turpentine is the most active ingre- dient. It is sometimes exhibited internally, for the cure of gleets. OLEUM TEREBINTH! NATUM. ft. Olei arnygdal® ^ss. Olei terebinthin® gutt. xr.. Misce. In deafness, occasioned by defective, or diseased action of the glandnl® cerumine®, Mr. Maule directs a little of this oil to be dropped into the patient’s ear, or applied at the end of a small dossil of cotton. WU*3U a thin secretion takes place, the OPHTHALMY. cure is also promoted by a small blister, which is placed as near the ear as convenient, and kept open with the savine cerate. The meatus auditorius externus must also be cleansed every day with a lengthened bit of soft cotton, affixed to a probe. (See Phar- macop. { shirurgica .) OMPI-fALOCE'LE. (from ojuyxkoc, the navel, and a rupture.) A rupture, or hernia at the navel. (See Hernia.) ONYCHlA. (ovw|, the nail.) An abscess near the nail of the finger. (See Whitlow.) ONYX. (from ovv%, the nail.) A small collection of matter, situated in the anterior chamber of the aqueous humour, and so named from its being shaped like a nail. It is of the same nature as Hypopium, to which word I must refer the reader. Maitre-Jean, Mauchart, and several other oculists, imply by the term onyx, a small abscess between the layers of the cornea. OPHTHALMY. (from opfla tx/aot, the eye.) Ophthalmia. Ophthalmitis. Inflammation of the eye. This is not only a consequence of several affections of the eye, and adjacent parts, on the existence of which other dis- orders its continuance entirely depends, but is frequently the primary complaint, and too often the forerunner of such irreparable mischief as for ever bereaves the patient of vision. The determination of a preternatu- ral quantity of blood into the organ, and fulness of its vessels, or a congestion, as se- veral writers express themselves, is, accord- ing to Beer, the earliest change which occurs in ophthalmy in general. The next symp- tom is said to be redness, which becomes more intense, as the disorder makes progress, and if the complaint be protracted, the red assumes a dark hue, then a brownish, and lastly a bluish tinge. However, when the arteries and veins affected soon return to their natural state, the redness of the textures of the eye may not attain the greatest in- tensity. Professor Beer seems to adopt si- milar views of the nature of the process of inflammation to those which are taken by Dr. W. Philip, and some other writers alrea- dy mentioned, (see Inflammation ,) for, in consequence of the small arteries and veins being deprived of their propelling power, he considers that the blood in the texture, w hich is the immediate seat of inflammation, is in a state of actual stagnation. ( Lehre von den Jhigenkrankheiten , B. 1 ,p. 30.) The third general symptom of ophthalmy, des- cribed by Beer, as closely following the redness, is a tense, hard, painful -swelling of the texture, directly affected. Lastly, in proportion as the pain, redness, and swelling are considerable, the more obvious is ano* ther common effect of inflammation, viz* an increase of temperature or heat. But although the disturbed intercourse between the arterial and venous systems is more ob- vious than the effects of inflammation in other parts of the organization of the eye, yet, that the secreting and excreting vessels, and the absorbents, are also affected, is evinced by the augmented secretion and excretion in the early stage of the disorder, followed, when the inflammation has be- come more intense, by a suppression of these functions, and a dryness and want of pliancy in the inflamed textures of the eye. The disturbance of the connexion between the nerves and muscles also produces first various involuntary movements, which, as the inflammation makes progress, become more and more limited, and, at length, there is a complete loss of action in the textures of the eye, which are the seat of inflamma- tion. But, inasmuch as every disease of the eye presents some differences, depending upon the nature of the disorder itself, and others arising from the peculiar organization of the texture, which happens to be principally affected, the characteristic appearances of ophthalmy must be subject to a vast num- ber of modifications, according as this or that structure of the eye is inflamed ; and hence, sometimes one symptom of inflam- mation, sometimes another, chiefly predo- ** minates, while Others are less conspicuous, and often scarcely distinguishable. Yet, says Beer, none of the characteristic marks of inflammation are ever entirely absent. This author represents the degree of pain as be- ing proportioned in a great measure to the tough unyielding nature of the parts imme- diately around the inflamed texture of the eye, to the firm nature of the inflamed tex- ture itself, and to the quantity of nerves with which such texture, and the parts in its immediate vicinity, are supplied. In proof of the truth of this doctrine, he in- stances whitlows and internal ophthalmy, where the .pain is very severe ; while in- flammations of the conjunctiva, not extend- ing to the deeper textures of the eye, are described as cases in which the pain is slight, because the structure affected is loose and yielding. But, without scrutinizing every reason assigned by Beer, for the va- rieties observable in the symptoms accord- ing to the texture which happens to be most affected, I shall briefly state a few 7 other ex- amples quoted by the same author. That the degree of redness, as well as of pain, varies considerably in different states of ophthalmy, is a fact universally known. In the beginning of the complaint, such red- ness is generally less perceptible than when the inflammation has attained its highest pitch ; but it is not equally great in every individual, nor in every species of ophthal- my, being sometimes more intense and dif- fused,' sometimes less both in degree and extent. This diversity is referred by Beer, and probably with reason, to the texture affected in the eye, being furnished with many considerable blood-vessels, obvious to the sight, or only containing vessels, more concealed and rather filled with a colourless fluid than with red blood. The looseness or unyielding nature of the texture is also represented as making a difference in the degree of redness. In inflammation, prin- cipally affecting the conjunctiva and sclero- tica, says Beeivthe redness is so intense, as to give the eye a frightful appearance, as i- OPHTHALMY. 296 seen in ciiemosis ; while in inflammations of the innermost textures of the organ, the redness is scarcely perceptible, and, in the erysipelatous inflammation of the eyelids, the redness is very faint, (j B eer, Lehre von den Augenkrankheiten , B. \,p. 34 — 36.) Dr. Vetch remarks, that the conjunctiva is capable of being stretched to a great extent, owing to the loose structure of the cellular membrane on which it lies, and consequent- ly little resistance is made to the enlarge- ment of its vessels. From slight irritation, they soon become distended with red blood, il but their tone or power of reaction is spee- dily exhausted, and, if the exciting cause is not kept up in an increasing ratio, they quickly fall into a chronic or varicose en- largement, or again contract to the diame- ter of the serous vessels.” On the other hand, (as the same experienced writer has pointed out,) inflammation of the sclerotic coat is slow in its commencement, and often insidious in its progress, even when its ulti- mate violence is great. In the early stage of conjunctival ophthalmia, the inflammation is most observable at a distance from the cornea , round which the membrane often preserves for a length of time its natural appearance. Precisely the reverse takes place in the case of sclerotic inflammation , which invariably ap- pears at the circumference of the cornea , forming a zone , more or less complete around it , and most conspicuous above it , the form and colour of the vessels being at the same time wholly different from those which appear in the course of conjunctival inflammation. Intolerance of light (says Dr. Vetch,) in va- riably accompanies sclerotic inflammation, and is entirely unconnected with that of the conjunctiva. (A Practical Treatise on the Diseases of the Eye, p. 10.) If the latter ob- servation be strictly correct, it is to be in- ferred that, in all common cases of acute ophthalmy, involving the conjunctiva on the front of the eyeball, the sclerotica is more or less affected, as in the beginning of the disorder, light may be said to be seri- ously annoying to every patient. According to Mr. Travers, when the scle- rotica partakes of the inflammation of the conjunctiva, the vessels, which pursue a straight course to the margin of the cornea, are strongly distinguished, and have a some- what darker hue, than the areol ar vessels upon the loose portion of (he conjunctiva. ( Synop- sis of the Diseases of the Eye, p. 128.) Diversified as the pain, redness, swelling, and heat, the four characteristic symptoms of inflammation, may be in cases of oph- thalmy, the incidental appearances in the eye are not less subject to numerous modi- fications. Thus, sometimes an extraordinary involuntary action of the muscles of the eyeball and eyelids, or of the secreting and excreting lachrymal organs, and of the Mei- bomian glands may be noticed ; and some- times the action of all these parts is either diminished, or completely stopped. These differences Beer refers to the latter parts being either themselves inflamed, or sympa- thizing with the inflamed texture of the eve lathe first case, the action of the muscles, and the functions of the lachrymal organs, and Meibomian glands, are more and more inter- rupted in proportion as the inflammation increases, and must thus remain, while the inflammation lasts in its genuine form ; but, in the second case, they go on, and this even with greater activity, while the inflam- mation continues, and until it has ceased to become more violent. ( B . 1 ,p. 39.) Acute ophthalmy in general, when at all severe, and particularly when the inner tex- tures of the eye are affected, produces a febrile disturbance of the whole constitution. This change from a local to a general indis- position takes place with greater certainty and quickness, in proportion as the focus of inflammation is extensive, the constitution irritable, the disorder of the eye neglected, and the mischief considerable, which is ac- tually produced in the organ, whether acci- dentally, or in consequence of unskilful treatment. (Beer, Vol. cit. p. 42.) Many of the appearances and effects of ophthalmy are different, as the inflammation happens to be of an acute, or chronic na- ture. And, as Scarpa has taken particular pains to impress upon the minds of surgical practitioners, every acute ophthal my, though treated in the best possible manner, is never so completely resolved as not to be followed by a certain period, at which ail active dis- turbance ceases, in the place of which a degree of chronic ophthalmy remains in the conjunctiva, or lining of the eyelids ; the effect either of local weakness in the vessels, or of the continuance of a morbid irritability in the eye, after the removal of the acute stage of the inflammation. As it occasions a diseased secretion in the organ, and a slow accumulation of blood and coagulating lymph, (he inexperienced are apt to suppose,, that the acute stage is not yet entirely sub- dued, while it is completely so. Now, if the inculcations of Richter and Scarpa be correct, immediately the critical moment arrives, when the acute stage changes into the chronic, attended with local weakness, it is of the highest importance to alter the treatment without delay, and to substitute for emollient relaxing applications, such as partake of an astringent corroborant quality, as the former only protract the turgescence of the vessels, and the redness of the con- junctiva. “Quo major autem fuit inflam- mationis vehementia (says Richter,) eq major pleruraque sequitur partiutn affecta- rum atonia, eoque major opus est adstrin gentium et roborantiurn longo usu, ut auferanlur penitus reliquiae inorbi, &,c." ( Fasical . Obs. Chir. 1 ,p. 109.) It is on the accession of the second stage of ophthalmy, that one may remark the sudden increase of redness in the inflamed texture, with a brown and afterward a blue tinge , actual extravasations of blood in the chambers of the aqueous humour; ecchy- mosis of the conjunctiva ; a considerable in- crease of swelling; the decline and irregu- larity of the pain ; the decrease of the in- flammatory heat and throbbing : a sensation OPHTHALMY 297 of cold and heaviness in the organ ; and more or le$s oedematous swelling of the surrounding parts. It is also in the second stage, that suppuration is liable to happen. (Beer, Lehre, fyc. B. 1, p. 46.) And in an- other page the same author observes, that the characteristic signs of the second stage of ophthalmy consist in the following ap- pearances : while the redness and swelling undergo a sudden and striking increase, the hardness manifestly diminishes, and the pain becomes very unequal, and not continual ; the secretions and excretions also, which, during the first stage, were completely stop- ped, commence again, but more copiously, and are of a very different quality from what they were in the state of health. The dis- order is now quite in its second stage, and this is the time when purulent matter may begin to be formed. (B. 1, p. 50.) Accord- ing to Beer, the duration of idiopathic oph- thalmy depends upon the circumstances of each individual case ; first, the nature of the causes giving rise to the affection ; se- condly, the irritability of the patient in re- lation to constitution, sex, and age ; thirdly, Avhat may be termed the constitution of the affected eye itself, and the texture in it im- mediately inflamed. Thus ophthalmy is like- ly to be attended with great severity, when it attacks plethoric individuals, in whom there has been for some time previously a great determination of blood to the head and eyes, or whose sight has been strained by looking at shining objects, or constitu- tions hurt by good living and hard drinking. Every severe ophthalmy runs through its first stage much more rapidly in weak, irri- table subjects and children, than in robust individuals. It is also another remark made by Beer, that every inflammation of the eye, at all considerable, is generally of shorter continuance in gray or blue-eyed, than in dark, or black-eyed perstms ; and in the same manner, inflammation of the in- ternal, sensible, and tender textures of the eyeball always passes through its first stage more quickly, than inflammation of the eye- lids. With respect to the causes of ophthalmy in general, as the disorder frequently affects the innermost parts of the eye, and when severe, is attended with some risk of the loss of the organ, the annihilation of its func- tions, or the spoiling of some of its textures ; and also, as inflammation is the most fre- quent complaint to which the eye is subject, il is important to learn, as far as possible, the causes, which either directly or indi- rectly give rise to it. jThe atmospheric air and light have a di- rect and powerful operation upon the eyes ; and in order that the former may have no hurtful effect upon these organs, it should be pure, that is to say, its regular component parts should not be altered, nor blended with extraneous substances. The tempera- ture of the air is likewise described by Beer, as making a good deal of difference in the susceptibility of the eyes for inflammation, either a very warm, or cold air, being, in Vol.H. 3s this respect, hurtful. The observation, how- ever, is qualified with the admission, that the terms warm and cold have only a rela- tive signification to individual circumstances. The effect of a blast of cold air on the eye, in exciting inflammation, is universally known, and needs no comment. It is an opinion of Beer, that the eye is much affect- ed by the quantity of electricity in the at- mosphere, and he says, that on this account, no experienced practitioner would under- take the extraction of a cataract during, or on the approach of a storm. ( B . 1, p. 65.) Passing over many interesting observa- tions made by Beer, on the contamination of the atmospheric air by the admixture of other gases, and the injurious effect of this change upon the eyes, I come to his re- marks on the operation of light upon these organs. Though light, he observes, is indis- pensable to the functions of the eye, it be- comes pernicious, when suddenly increased beyond what the organ can bear, so as to be a source of irritation As a proof of this fact, he cites an instance, in which a young, plethoric, strong man, whose eyes had been for some time unavoidably strained by im- moderate exercise of them, was suddenly attacked with a violent ophthalmy, while looking at an optical representation of the rising sun, and carried home in great agony. But with respect to the influence of light^ Beer observes, that every statement is to be received only in a relative sense ; for the degree of light which would answer very well for the eye of an African, would de- stroy many European eyes ; and the same light, which is borne without inconvenience by the eye of an adult, would excite in the eye of a new-born infant the ophthalmia neo- natorum , by which so many children are de prived of the most valuable of the senses in the first days of their existence. Beer fur- ther explains, that the same degree of light produces a stronger, or weaker effect, ac- cording to the greater or lesser irritability of the eye of the same person at different times, as we see exemplified in every indi- vidual in the tenderness of his eye to light when he first awakes in the morning. Light is also not hurtful to the eyes, merely ac- cording to its quantity ; for the direction of the rays makes a great deal of difference, the eye being less capable of bearing them with impunity the more they recede from a perpendicular line, and strike the organ slo- pingly, or horizontally. Much likewise de- pends upon the kind of light ; that which is reflected from a scarlet surface, being even more prejudicial than the sunshine which is reflected from a country covered with snow ; another convincing proof, that the bad effects are not always in proportion to the quantity of rays. The light of burning- glasses, concave mirrors, white screens, the full moon, &c. and the shining of diamonds, are well known to render the eyes weak, and prone to inflammation. Among other occasional causes of ophthalmy, Beer enu- merates the custom of washing the eyes im- moderately with cold water, a renjark in ophthalmy. 2f rs which I do riot place much confidence my- self; the application of various stimulating medicated substances to them ; compresses and bandages : the badness of instruments employed in operations upon the eyes ; the employment of spectacles unnecessarily, or of such as are not adapted to ibe eyes of the individual ; and every immoderate ex- ertion of the eyesight. But, among the most important and fre- quent exciting causes of ophthalmy, are extraneous bodies, which insinuate them- selves between tire eyeball and eyelids, and every kind of wound or injury of the eye. Foreign bodies, liable to enter under the eyelids, are of three kinds; first, they may either be such as are in themselves corn pletely innoxious to the eye ; or such as are likely to hurt the eye only when strongly pressed upon by the spasmodic closure of the eyelids, or by the patient's imprudently rubbing the eye ; or they may be of a qua- lity which injures the eye the moment they come into contact with it. Foreign bodies of the first description lie loose under one of the eyelids, and, for the most part, either immediately behind its edge in the groove destined for the conveyance of the tears, or else in the fold, seen when the eyelid is everted, exactly at the line where the pal- pebra and sclerotic conjunctiva join toge- ther. They never actually lodge in the coats of the eye ; but they irritate it either mechanically or chymically, or in both ways together, according to their size, shape, and chymical properties. In the list of such extraneous substances are inverted eyelashes ; particles of dust ; snuff . pepper . minute insects ; and other small things generally carried under the eyelids by the wind. As these foreign bodies are all of them more or less irritating to the eye, they mud Be considered as a principal exciting cause ©f ophthalmy, which frequently follows their entrance under the eyelids with extra- ordinary rapidity. However, the redness and effusion ot tears, sometimes instantly following the insinuation of extraneous sub- stances under the palpebrre.and as suddenly ceasing on their removal, Beer considers rather as preliminaries to inflammation, than as this disorder itself. (B. 1 ,p. 92.) Wounds and other injuries of the eye, regarded as causes of ophthalmy, Beer di- vides into three kinds ; viz. mechanical, chy- mical, and mixed. A prick of the eye with a fine needle is an example of a simple me- chanical injury ; the action of quicklime upon the organ is an instance of one purely chymical ; and the violent propulsion of a red-hot bit of iron against the eye is a le- sion, which may be said to be both mecha- nical and chymical. The same author makes a variety of original reflections upon the differences connected with the extent and intensity of such injuries. Their intensity, be views only as something relative ; thus, either the force, with which the eye is inju- red, is of itself too great ever to be resisted, as is seen in a gunshot wound ; or the organic powers of the patient are, from age, sex, c/r constitution, much too feeble for the eye to bear favourably any considerable injury, as is the case with children and weak unheal- thy females ; or the organization of the eye itself may Ire weak, and the effects of the violence therefore greater, as exemplified in the fact of a brown or black eye generally bearing a wound better than a gray or blue one ; or, lastly, the organic powers of the texture of the eye, immediately injured, may be too feeble to bear even a slight le- sion, as is the case with the retina. (B. 1, p.9o.) Mechanical injuries of the eye may be made either with sharp or obtuse bodies. Sharp-pointed and cutting instruments are capable of readily penetrating the eye, without occasioning at the moment of their entrance, any violent compression, or lace- ration of the neighbouring textures ; and consequently the injury inflicted is a simple puncture, or an incision. Sabre-cuts of t he eye, however, are to be excepted ; for, though the weapon may be sharp, the blow' is always attended with more or less con - cussion, and injury of the textures, adjoin- ing the wound, which are very delicate and readily spoiled. Blunt weapons, or bodies, can only enter the texture of the eye by dint of great force, and, in this case, always cause a serious degree of compression, stretching, and laceration ; but sometimes when they do not penetrate the organ, the contusion is such as is productive of not less mischief. In the case of a simple puncture or inci- sion of the eye, Beer seems to think that the subsequent ophthalmy is generally more owing to the incapacity of the wounded or- gan to bear the effects of the light, air, he. than to the injury itself abstractedly consi- dered. He observes, that a proof of the truth of this opinion is seen in the extraction of the cataract ; for, if the operator is care- less in the operation itself, opening the flap of the cornea very wide, so as to let the at- mospheric air have free access to the inner textures of the eye ; or if after the operation is finished, he do not apply the dressings with caution, and properly darken the pa- tient’s chamber, he is letting the eye he sub- jected to some of the most active causes of inflammation. But though Beer is unques- tionably correct, in regard to the injurious effects of light on the W'ounded eye, it may be doubted, whether his theories do not make him attribute too much to the irrita- tion of the air, and too little to that of the mechanical division of the parts. Passing over many of Beer’s observations on injuries of the eye produced by blunt bodies, and substances acting chymically upon it, 1 leave the topic of the direct exci- ting causes of ophthalmy, and come to the consideration of those which lie regards as indirect. And the first to which he adverts, is every thing that has a tendency to keep up a determination of a large quantity of blood into the small vessels of the head and eyes. Immoderate bodily exercise ; violent GJPHTHALM*. 299 emotions of the mrnd ; injudicious clothing ; and high living, are afterward enumerated as having an indirect effect in the produc- tion of ophthalmy; but it does not appear to me, that Beer's sentiments upon these points are entitled to much attention. With respect to infection and contagion, as causes of inflammation of the eye, Beer under- stands by infection, what at first takes effect only upon a small point of the body, but never the whole animal economy directly, that is to say, before absorption has taken place. Hence, says he, infectious diseases are very seldom the cause of ophthalmy, unless some of their matter be applied im- mediately to the eye itself; but he admits that they often dispose this organ to inflame from slight causes, by the impairment which they produce of the general health On the other hand, he considers all contagions as very quickly affecting the whole of the con- stitution directly through the medium of the skin, or the trachea, lungs, oesophagus, &c. Hence, contagion is set down as being much more frequently, than infection, the indirect cause of ophthalmy. Beer conceives, how- ever, that as the contagious principle is blended with the atmosphere, it may also have an immediate operation upon the eyes, and thus he attempts to account for the or- gans not unfrequently exhibiting a tendency to inflammation at the very moment of the contagion taking effect. (3. l,p. 121.) But this is a difficult and obscure subject, which can be viewed to more advantage when particular kinds of ophthalmy are considered. In Beer’s general observations on the treatment of inflammations of the eyes, the first indication specified, is to remove imme dialely every thing, which is obviously produ- cing an irritating effect upon the eye and to take care that no fresh source of irritation to the organ incidentally lake place. And, as Itfrequently happens, even in healthy, strong individuals, that ophthalmy is occasioned by foreign bodies, either lodged under the eye- lids, or inserted in some part of the eyeball, and not suspected to be there, the earliest attention should always be paid to their gentle and skilful removal. Easy as this object is of accomplishment, when not de- layed, when the eye has not been seriously irritated by friction and pressure, and the patient is not of a weak, irritable constitu- tion, it is often attended with great difficulty under one, or the other of these circumstan- ces, especially the last. In this case, strong convulsive rotations of the eyeball, followed by a violent and obstinate spasmodic closure of the eyelids, render it impossible to sepa- rate them ; and the spasm is the stronger and more lasting, the more -the extraneous substances are calculated by their shape and ehymica! quality, to irritate the eye ; and the greater the irritability of the patient is. In this state of things, every attempt forcibly to open the eye, or to examine it in the light, is not oniy useless, but increases and keeps up the spasm, which nothing will lessen and shorten, except darkness and perfect repose. But, as timid irritable persons are exceeding- ly apprehensive of the consequences of the lodgment of extraneous substances in the eye, the surgeon should endeavour to lessen their inquietude, by assuring them that every thing will be right again, which is strictly true when the foreign bodies are of the first class. Then the spasmodic closure of the eyelids will cease, and the extraneous sub- stance admit of being properly taken away. Success, however, does not always attend this simple method ; for, in very weak sub- jects, the spasm of the orbicularis palpebra- rum is so violent and obstinate, especially when a foreign body lodges in the eye, and at the same time mechanically and chymi-' cally irritates it, (as is the case with particles of snuff,) that it becomes indispensable to have recourse to medicinal applications. For this purpose, Beer’s experience has convin- ced him, that the best thing is a bread poul- tice, made either with milk or water, and containing some of the vinous tincture of opium. Care is to be taken, however, never to let it become quite cold, during its appli- cation ; for then the spasm would only be aggravate.! by it ; and if such spasm has been of long continuance, when the surgeon is first sent for, the poultice, according to Beer, may be rendered more efficacious bv tlie addition of hyosciamus to it. In very irritable hysterical and hypochondriacal per- sons, such local treatment alone is frequently insufficient, and recourse must be had to the internal exhibition of antispasmodic ano- dyne medicines. At length, when the spasm of the orbicular muscle is so far diminished, that the eyelids can be effectually opened without any force for the extraction of the foreign body, great caution and gentleness will yet be necessary, and, in particular, the eye should be kept in a very moderate light, as the spasm would be immediately excited again, either by sudden exposure of the eye to too much light, or rough handling of the eyelids. Sometimes, a person rubs his eye at first awaking in the morning, and if the eyelashes are very numerous and rigid, one of them will lodge between the eyeball and lower eyelid : it may readily be taken away with the end of a fine moist sponge, or camei- hair pencil, the eyelid being depressed ns much as possible and the eye itself turned upward, so that the hair may not be conceal- ed in the fold of the conjunctiva. When the hair is situated underthe upper eyelid (which Beer says rarely happens) it always lodges in the fold of the preceding membrane, whence it may be extracted in the manner above directed, with the difference tiiat the eyelid must be raised or everted, and the eve rotated downwards. (Lehre von den Krankh. B.\,p. 128, 130.) For directions respecting the treatment of redundant and inverted cilia?, see Dislichiasis and Trichiasis. Small globular smooth extraneous bodies, lodged under the eyelids, are very easily ex- tracted, when the eyelid is gently taken hold of both byits edg? and the eyelashes, and tiff, ed up from the eye, while the patient inclines OPIITHALMY. m hishead forwards, and the eye is turned com- pletely downwards : the effusion of tears, excited by these manoeuvres, will now gene- rally wash these extraneous substances out of the eye, as they are not at all fixed. When the fissure between the eyelids is wide and open, but the eyeball at the same time very prominent, the object may also be easily accomplished, when the upper eyelid is gently and repeatedly stroked with the finger from the outer towards tiie inner canthus ; in which case, the round smooth foreign body soon makes its appearance above the caruncula lachrymalis, whence it falls out of itself, or may be taken with the corner of a pocket handkerchief. The worst cases are those, in which the eyes are very prominent, and the fissure of the eye- lids small, as ail the above methods are then useless, and only productive of irritation. In this circumstance, therefore, Beer recom- mends the surgeon to take hold of the eye- lid by the cilia;, and its edge with the thumb and forefinger, and separate it from the eye- ball, w hich is to be tui ned downw ards, while, with Daviel s small scoop, or the head of any large curved needle, introduced straight under the eyelid, at the outer canthus, as high as possible, the extraneous substance is to be extracted with a semicircular move- ment, directed towards the nose. Though this method will almost alw ays succeed, Beer confesses, that it is not without the pro- duction of a great deal of mechanical irrita- tion. In consequence of the detention of such substances under the eyelids, the* conjunctiva sometimes becomes thickened ; this change, when slight, soon disappears of itself alter the removal of the foreign bodies ; but, iu other cases, Beer recommends the diseased part of the membrane to be removed with a pair of scissors ; and, after the bleeding has ceased, the frequent application of the lotio plumbi acetatis to the eye. Particles of common dust, and of the sand and powders, frequently thrown over letters, and very apt to get into the eyes of persons who open their letters carelessly, or from short-sightedness, are obliged to bring them close to the nose, are generally more difficult of extraction. In the attempt, however, the eye must never be subjected to too much irritation. According to Beer, these extraneous particles of dust, or sand, may sometimes be removed by washing the eye well, or by dropping into it milk, or some other viscid fluid, while the patient lies upon his back, and the eyelid is lifted up from the eye. But, the most expeditious and certain plan is to employ a syringe, the pipe of which is to be introduced under the upper eyelid near the outer canthus, and the fluid thrown briskly in the direction towards the nose. If all the extraneous matter can- not be thus removed, the rest may some- times be taken out with a camel-hair pencil, dipped in some viscid fluid, or fresh butter, and the eye is then to be washed again. When particles of sugar, or other soluble, not very irritating substances, happen to in- sinuate themselves into the eye, professional aid is seldom required, as they generally dissolve in the tears, and are voided before a surgeon can arrive. Snuff, pepper, and other minute irritating bodies, as well as small winged insects, are to be removed in the same manner, as particles of dust and letter-sand ; but, particular care is to be taken afterward to wash the eye well with some lukewarm mucilaginous coliyrium, until the irritation, caused by the chymical effect of such foreign bodies, has been com- pletely obviated. The removal of foreign bodies of the second class is usually attended with more difficulty, because they, as well as those of the third class, more frequently produce a violent and obstinate spasmodic closure of the eyelids, and are seldom loose, being generally fixed in the cornea. However, when they happen to be detached, they may be extracted in the same way, as small round smooth extraneous bodies, except that the stroking of the eyelid with the finger should be omitted, not only as useless, but likely to press any of these sub- stances, which are of a pointed shape, into the loose conjunctiva, so as to injure the eye itself, which would otherwise not be hurt, l he nibs of pens, the parings of the nails, and s’inall hard-winged insects, when lodged in a depression of the cornea, or white of the eye, Beer says, may be easily dislodged by means of a small silver spatula. Other foreign bodies of the second class are not only fixed in a depression, but even penetrate more deeply than the conjunctiva • and, in old subjects, in particular, they often insinuate themselves into the loose cellular membrane under the conjunctiva in the white of the eye, partly in consequence of the convulsive motions of the eyeball and eyelids, and partly by reason of the attempts made to loosen them. Hence, they frequently become situated a great way from the place of their entrance, and are complete!) covered by the conjunctiva. But, even when they lie immediately in the wound, they are so intimately connected with the subjacent luose cellular membrane of the conjunctiva, that every attempt to remove them with forceps is not only una- vailing, but hurtful to the eye, inasmuch as the injury is thereby rendered deeper. They may be taken away with facility, however, when lifted up with a pair of small forceps, and are cut away withja pair of scissors, toge- ther with the piece of cellular membrane, with which they are directly connected. If such extraneous substance should be ac- tually underneath the sclerotic conjunctiva. Beer recommends the eyelids to be well opened, and the eye to be brought into a position, in which the part of the conjunctiva covering the foreign body, is rendered tense when an incision is to be made with a lancet down to the extraneous substance, which is to he taken hold of, and removed with a pair of scissors, the assistant being curetul to keep hold of the eyelids during the ope- ration,. On the other hand, when the i OPHTHALMY. ‘6i)L foreign body is actually lodged between the layers of the cornea, Beer considers that its extraction may be best accomplished with a lancet-pointed couching needle. But, what- ever instrument is used, its point must be passed with great caution closely and ob- liquely under the foreign body ; and care must be taken not to introduce it too deeply, lest the anterior chamber be opened, which may readily happen in young subjects ; and when it does, the aqueous humour flows out, and the cornea becomes so flaccid, that the removal of the extraneous substance is quite impracticable, before the puncture has heal- ed, and the anterior chamber is again dis- tended. The removal of foreign bodies of the third class mostly demands very great cau- tion, first, because, as Beer observes, no particles of them should be allowed to re- main in the eye, which, without the utmost vigilance, is apt to be the case ; and second- ly, because the wound of the eye, already considerable, should not be made larger than can be avoided. The extraction of small bits of glass is particularly difficult, as they cannot be seen, but must be found out entirely by the feelings of the patient, or the tactus eruditus of the surgeon, assist- ed with a probe. When in this way, a particle of glass is detected, Beer directs us to take hold of it with a pair of forceps, and cut it away with scissors. The place from which it has been removed, must then be carefully probed, in order that no other fragment may be left iri it. {Beer.) According to the same author, pieces of iron and steel, which strike the eye so forci- bly as to enter it, as well as all other frag- ments of metals, which are readily oxyda- ted, should be as carefully removed as bits of glass; for the more easily they combine with oxygen, and the longer they remain, the more brittle they become, and the more apt are minute particles to be left in the eye, especially in the corneR. A speck on the part of this membrane, where the splinter has lodged, is the least serious con- sequence of such an event. When frag- ments of steel, which have quite a black appearance, remain fixed in the cornea several hours, it is found, after their removal, that the whole circumference of the depres- sion, from which they have been extracted, is of a reddish-brown colour, produced by the rust left behind, and firmly adhering to the cornea. Every particle of rust must be carefully removed with a couching needle, or else a permanent speck will ensue ; but, caution must be used not to puncture the anterior chamber. The extraction of parti- cles of lead and gunpowder is generally difficult, as they have mostly been project- ed with great force against the eyelids, so as to produce not only a great deal of spasm, but instantaneous swelling of those parts. Hence, Beer says, that they should com- monly be taken hold of with forceps, arid cut away. Particles of cantharides are easi- ly removed with a small silver spatula, or the end of an eye-probe : but, their violent chymical effect must be obviated, by fre- quently applying to the part a little fresh butter, touching it with a camel-hair pencil, dipped in diluted liquor ammonia?, or drop- ping into the eye lukewarm mucilaginous collyria. The attempt to wash out of the eye parti- cles of quicklime, mortar, he. Beer says, only has the effect of rendering the violent chymical operation of these substances more diffused, and he recommends them to be ta- ken out of the eye, by means of a fine hair pencil, dipped in fresh butter, or oil. This is the only way of immediately counteract- ing their chymical effect, and, after their extraction, the application of unctuous sub- stances to the part should still be continued. The stings of small insects, when lodged in the sclerotic conjunctiva, are often very difficult of detection ; but they are more readily seen on the skin of the eyelids. Beer directs us to remove them with a pair of forceps, or a couching needle, and then to have recourse to means calculated to diminish the ophthalmy, which, in these ca- ses, always begins on the first occurrence of the accident. Small shots, lodged in the loose cellular texture of the conjunctiva, must be cut out. In general, says Beer, it is necessary to divide the conjunctiva, as they are mostly situated some distance from the place of their entrance, and of course are quite covered by that membrane. As soon as a foreign body has been ex- tracted from the eye, all precursors of oph- thalmy diminish, as for instance, the redness, intolerance of light, and the increased se- cretion and effusion of tears. Even the in- flammation itself, when already developed, subsides; but, this affection is slight, if the eye has not itself been injured by the extra- neous body. On the other hand, when the eye has suffered more or less irritation from the nature of the substance itself, and the treatment requisite for its complete extrac- tion, the inflammation may become more severe, unless the surgeon pay immediate at- tention to the injury left on the eye. (Beer.) According to the principles laid down in the foregoing columns, the first indication in the treatment of wounds of the eye in gene- ral is to remove every kind of extraneous substance, which might impede the cure. Hence, the necessity of observing whether the instrument with which the wound has been inflicted, or any part of it, is lodged in the eye. When this is the case, the foreign body 1 " should be quickly extracted, oreise no recovery of the organ can take place. But, says Beer, this is more easily said than done ; for in many instances, it is very difficult to find and remove the fragments of instru- ments, on account of the great delicacy of the. organ, the irritability and alarm of the patient, and the bleeding from the part. However, the attempt must be made with the greatest gentleness possible ; and Beer particularly advises a fine elastic whalebone probe to be used, instead of a silver one, for the purpose of detecting the fragment He also sanctions making an incision, for facili- OPHTHALMY. tating the finding of the extraneous sub- comes both unnecessary and impracticable., stance, provided it is certainly lodged, and and all that can be done is to drop frequent- cannot otherwise be traced. This aulhor ly into the eye a mucilaginous colly rium, attaches great importance to the fulfilment and cover the organ with a light bandage, of this first indication n all wounds of the which will not make any hurtful pressure, eye, and relates a case, to which he was In simple contusions of the eye, unaccom- called sixteen years ago, where a piece of panied with wound, Beer deems a bandage tobacco pipe had been driven so forcibly and the otdy requisite application ; but, when deeply at the external can thus between the these accidents are co joined with effusion eyeball and orbit of a young student, aged of blood, he recommends the use of spiri- ts), and of delicate make, that the eye was tuous aromatic fomentations, with the view immediately pushed out of its socket, and, of promoting absorption, on Beer’s arrival, it lay with the cornea In healthy individuals small punctures of quite against the nose. Its very position led the eye, made with instruments like needles, Beer to suspect, that some extraneous body and perforating only the conjunctiva, or was lodged in the orbit, and, notwilhstand- cornea, but not reaching the deeper textures ing the assurances of all the bystanders to of the organ, are generally followed by no the contrary, and the patient’s being affected serious consequences, even when all the with violent spasms, he part was examined aqueous humour is voided. It is only ne- Xvith a fine flexible whalebone probe, by cessary to keep the eye quiet, and the air which means, a piece of the pipe, nearly an and light excluded from it by means of alight inch in length, was felt, and immediately compress, suspended over it from the fore- extracted with a pair of forceps. Scarcely head. Under this treatment, such punctures had this substance been removed, when the are so firtnlyclosed in twenty four hours, with- ©yeball was spontaneously drawn back into out any opacity, that the chambersare nearly the orbit, though w ith the cornea still turned filled again with aqueous humour, and the towards the nose, and the twiichings of the intoleranceof light, which was only the effect muscles also instantly ceased ; but the eye of the loss of that fluid is entirely removed. Was blind, and had but a very faint percep- In large clean cut wounds of the eye, tion of light. By very careful treatment, the whether accidental or made in the extraction eyesight was restored in five weeks ; but, of the cataract, the prognosis must be very the eye could not turn towards the temple, cautious, and the treatment conducted with owing to the considerable injury, which the the utmost care ; for, says Beer, it too readi- external straight muscle had sustained. With ly happens, that, though the wound is not the aid of electricity, the power of rotating important in itself, its effects become from the eye about half its natural extent out- the least mismanagement highly dangerous wards was in the end regained, and the re- to the eye. Hence, when the patient is maining infirmity resisted every method, known to be either an individual not likely deemed worthy of trial. (Beer, 8. 1, p. 146. to take proper care of himself, or one too See also the article Exophthalmia.) much alarmed about tbe fate of his eye, the Fragments of broken instruments are not prognosis should be very guarded, even the only kind of extraneous substances, where the eonsitution is of the best descrip- which may lodge in the wounded eye ; for, tion, because a violenl and dangerous attack as Beer observes, when the injury is exten- of ophthalmy is apt to ensue, and destroy sive, contused, and lacerated, there may be the eye, sooner than effectual succour can splinters of bone, or pieces of membrane, be administered. On the other hand, when cellular substance, muscle, &.c. so detached the patient is steady and intelligent, and the as to be quite incapable of reunion, on case is properly treated, the prognosis is very which account, this author sets them down favourable. as foreign bodies requiring to be taken away. In considerable cuts of the eye, it is only However, I conceive, that, with respect to possible to promote their union with asuita- fhe soft parts, the advice here delivered ble bandage, and by effectually preventing should be received with much limitation all motion of the eye and eyelids, which is Wounds of the eye, like those of most best accomplished, when the sound as well other parts of the body, may be healed as the injured eye is covered, and the patient either by direct union, or a slower process, kept quiet in bed until the sidesof the wound in which suppuration, the filling up of the have grown together. (Beer, B. \,p. 164.) chasm, by granulations, and the gradual but As cases of deeply penetrating wounds of not complete approximation of its edges to the eyeball itself, Beer enumerates the punc- each other, are the most conspicuous effects, tures made in the depression and reclination Clean incised wounds may be cured in the of the cataract, and in every mode of form- first way, (see Cataract ;) and lacerated, ing artificial pupil ; and lacerations of the contused wounds, or such as are attended co junctiva with ears of corn, pointed pieces with loss of substance, in the second. But, of iron, splinters of wood, &.c. In these whichever plan be attempted, the eye must cases, the prognosis, he says, is always very be kept quiet, and excluded from the air and favourable, when the patient can put him- light, with a light suitable bandage As in self under all t lie conditions which the treat- wounds arid chymical injuries of the eyeball rnent requires, and his constitution is good, itself, not admitting of reunion, tiie eyelids, The first thing here to be carefully fulfilled, when dosed, completely cover the wounded is the removal of any fragments of the in- part, , the application of dressings to it be- sfrument, or body, with which the injury ha** OFHTHALMY been inflicted, and it should be recollected, that, in these cases, minute splinters, which are scarcely discernible, frequently lodge in the conjunctiva, and, if not immediately tra- ced and removed, produce the very worst consequences. By the weapon being sud- denly withdrawn, pieces of the conjunctiva are sometimes nearly torn away, and hang from the eye ; these Beer directs to he cut off with scissors. The best applications, he says, are either lukewarm mucilaginous lo- tions, or, (when blood is effused under the conjunctiva,) vinous, spirituous collyria. To these cases, he thinks fomentations scarcely applicable. When the quantity of blood, effused in the loose cellular texture under the conjunctiva, is very considerable, he recommends scarifications but, where this practice does seem likely to answer, and vinous spirituous collyria are ineffectual, some of the liquor ammonia? should be added to them. When any fragment of the instrument has been overlooked, and remains in the part, either a copious suppuration en- sues, and the fragment is at length detached, or else, in a patient of inferior sensibility, a soft, spongy, readily bleeding, pale-red ex- crescence is formed all round the extraneous body, and sometimes even projects between the eyelids. Here, according to Beer, the first requisite step is to cut away the fungus with a knife, so as to reach the irritating frag- ment under it, and then the rest of the ex- crescence may be removed by touchingit wit h the tinctura thebaica, or vinous tincture of Opium. With respect to lacerated wounds of the cornea, they either penetrate the anterior chamber, or not. They are all of them at- tended with more or less concussion, lacera- tion, stretching, and partial contusion of the delicate anterior textures of the eyeball ; a consideration, as Beer observes, materially affecting the prognosis. When, in such in- juries of the cornea, inflammation and sup- puration cannot be prevenied, or the dis- charge is protracted, an obvious scar is always the consequence, which, when situa- ted in the centre of the cornea, is a serious impediment to vision. Every endeavour should therefore be made to unite the wound by the first intention ; and the best chance will be afforded by treating the eye precise- ly in the same manner ns after the extraction of the cataract. (See alaract ) And. whi n fortunately the plan succeeds, the flow of the aqueous humour out of t he eye ceases in about 36 or 48 hours, and the anterior chamber becomes distended again ; but, the site of the injury continues visible for some time afterward. The speck, however, ulti- mately disappears, though much sooner in young healthy subjects, than in the aged and feeble. When the opacity does not go off of itself, Beer finds a collyrium, containing some of the lapis divinus, (see Lachrymal Organs ,) and the vinous tincture of opium, the most effectual means of dispersing it. Through large wounds, penetrating the cor- nea near its edge, a fold of the iris is apt to protrude, and, when it does, it should be re- 30ii placed, which can only be effected without mischief to the eye by gently rubbing the upper eyelid, and then letting a strong light suddenly strike the organ. In this case, the employment of\ instruments is < onsidered by Beer highly objectionable. When the iris is not immediately reduced, it as well as the cornea is attacked with inflammation; and soon becomes firmly adherent to the edges of the wound. (S te Iris, Prolapsus of the,) Large wounds penetrating the eyeball, and reaching, to the ris, are always of a very serious nature, even though the latter part may have received only a prick, or cut, be- cause as tile injury iias been produced by accident, and not by art, the wound of the iris cannot be free from all laceration and contusion. It is incredible, says Beer, what extensive injuries the iris will bear in healthy individuals at its pupillary and ciliary edges, especially when produced bv very sharp" in- struments; nay, rents n ay happen at noth its edges, without any ill consequences, if the constitution be favourable; a proof of which fact is seen in the two common me- thods of forming an artificial pupil viz. tho excision of a piece of the iris and the de- tachment of the iris from the ciliary liga- ment, as practised both by Schmidt and Scarpa. But, according to Beer, all violent pressure, or actual contusion, particularly when it affects the portion of this organ be- tween its tw o circles, cannot be borne even in the best constitutions, and the least grie- vous consequence is inflammation, oon fol- lowed by a partial or complete closure of the pupil, or suppuration in the eyeball. When the instrument, causing such injury, passes to the iris through the cornea, as is mostly the case, and the wound in the latter tunic is extensive, the torn iris is frequently pulled between the edges of the wound, at the moment when the eapon is withdrawn, and protrudes in a lacerated state. In this case, Beer recommends the torn projecting piece of the iris to be cut away with scis- sors close to the wound in the cornea, when the rest, he says, is generally retract- ed within the eye. Thus an adhesion of the iris to the cornea, termed synechia anterior , may often be prevented, which, when the lacerated iris is suffered to hang out of the cornea, is inevitable, surrounded by a large opaque cicatrix. Some violent blows on the eye, though they cause no woi nd, are attended with such a concussion of the anterior hemis-- ph re of the organ, that more or less of the iris is instantaneously separated from the part of the ciliary ligament, where the force is most vehement. The consequence of this accident is either a double pupil, or the natural pupil closes, and the artificial one remains open. Such injuries may be pro- duced by the lash of a whip, or a horse’s tail, (a common accident in the narrow streets of Vienna) or the thrust of any bluntish weapon against the outer part of the cornea ; and they are purposely inflict- ed in the method of forming an artificial. 0PHTHALM5T. ‘M pupil, recommended both by Schmidt and Scarpa. Wounds which enter the eye through the sclerotica near the cornea, usually produce a considerable effusion of blood in the chambers of the aqueous humour; but Beer thinks that there is never any necessity for making an opening for its discharge at the lower part of the cornea, except when it is so considerable as completely to hide the iris, at the same time that the eyeball is affected with very painful tension and hard- ness. In all wounds of the iris, it is like- wise proper to follow the same treatment as applies to penetrating wounds of the cor- nea, with this difference, that when the effusion of blood in the chambers of the eye is considerable, the action of the absorbents should be promoted by the immediate em- ployment of vinous aromatic collyria, and afterward warm spirituous lotions. Wounds of the eyeball, affecting the cor- pus ciliare, are set down by Beer as ex- tremely dangerous, independently of the inflammation, which quickly follows. How- ever, such injuries are most serious when they consist in a real contusion, or lacera- tion of the corpus ciliare, >vhich can hardly take place without a severe concussion, or actual disorganization of the retina, and laceration of the principal ciliary nerves and vessels. Hence, besides an effusion of blood in the chambers of the aqueous hu- mour, a partial or complete amaurotic blind- ness' is instantly produced, and the iris, in the vicinity of the place where the instru- ment entered, is so retracted towards the margin of the cornea, that neither of its circles can be seen. In cases of this de- scription it also frequently happens, says Beer, that the patient, or the person who inflicted the wound, suddenly and roughly pulls the w r eapon out of the eye again, and together with it a part of the corpus ciliare, which is then to be regarded as an extrane- ous substance, and immediately cut off. With respect to the prognosis and treatment, the observations already made on these topics, in reference to wounds of the iris, are here quite applicable, excepting that as the effused blood is less copious than in the latter cases, there can never be here any necessity for letting it out by a depending opening in the cornea. Wounds of the eye, affecting the crystal- line lens, are not unfrequently follow ed by the formation of a cataract, and so are blows on the eye, which may be supposed to pro- duce this effect by destroying some of the minute nutrient vessels naturally connect- ing the capsule w ith the lens. (Beer, B. 1, p. 218.) The treatment of these accidents resembles that of injuries of the iris, except that the surgeon has rarely any extravasation of blood to deal with. However, when the lens has slipped into the anterior cham- ber, Beer recommends its immediate extrac- tion through an incision in the cornea, in order to prevent the eye from being de- stroyed by a violent attack of traumatic inflammation and suppuration. Nor -when inflammation has come on, should this mea sure be postponed, as Beer has constantly found the disorder lessen, after the lens has been taken out. Considerable w ounds of the eye, attend- ed with loss of the vitreous humour, are described by Beer as of a very serious na- ture ; but they rarely take place acci- dentally, being almost alw r ays the conse- quence of a surgical operation. Accidental injuries of this kind are generally combined with so large or complete a discharge of the vitreous humour, and with such mischief to the organization of the eye, thal the conse- quence is a loss of the eyeball, or such a dwindling of it, that the fissure of the eyelids becomes nearly closed. Accord- ing to Beer’s experience, injuries of the foregoing kind, arising from accident, are mostly produced by the horns of cows. On the contrary , the effusion of the vitreous humour in operations upon the eye, he ob- serves, is seldom followed by the loss of the eye. Kortum, in his Manual on the Disea- ses of the ftye, adverts to some instances which he had seen, or fancies that he had. seen, w r here the whole of the vitreous humour was lost, and yet the eyesight afterward be- came as strong as if no such accident had happened. On the other hand, Beer has never met with any of these fortunate cases ; but has always found the sight to be seriously impaired when the quantity of vi- treous humour lost has amounted to nearly its half, and that complete blindness w r as the result w r hen the loss much exceeded that quantity. He conceives also, that Kortum had probably seen but few cases of this nature, and therefore might have been mistaken, as to the proportion of the vitre- ous humour discharged, which to the inex- perienced seems larger than it really is, and he cautions surgeons not to promise too much in cases of this description. (B. 1 ,p. 222.) See Cataract. Considerable injuries of the eyeball, com- plicated with a concussion, bruise, or actual wound of the retina, produce, either gradu- ally or immediately, an amaurosis, which is almost always incurable. When the con- cussion of the retina is less violent, and does not affect every part of this texture, it may occasion only an amaurotic weakness of sight. In worse cases, the surgeon mny think himself very successful if he can pre- vent the figure of the eye from being de- stroyed by the subsequent inflammation, all idea of the recovery of the eyesight being out of the question. The treatment is the same as that commonly adopted after ope- rations for the removal of an opaque lens (see Cataract ;) but there is one particular circumstance, sometimes attending injuries of the retina and ciliary nerves, claiming notice, viz. violent vomiting; a symptom which Beer says may even attend contu- sions of the sclerotica and of the ciliary nerves and retina, without any wound. In- juries of the ciliary nerves, he observes, are denoted by a very peculiar appearance ; for, near the injured part, the iris is drawn up OPHTHALMY. 0O0 ao close 10 the edge of the cornea, that its strongish mineral acids. And even in these colour can scarcely be seen. When the examples, says Beer, the prognosis is net surgeon is consulted in a case of this kind, unfavourable, and a complete recovery though some inflammation may have com- may be effected when the treatment is con- menced, the prognosis is yet favourable, in ducted according to the directions already regard to the preservation of the eye ; for a given with respect to such accidents in gentle opiate will relieve the vomiting when merely a nervous effect, not depend- ing upon the loaded state of the gastric organs but, if the case be of this last de- scription, the prima 1 viae should first be emp- tied. However, when a traumatic inflam- mation is con.pletely established, before the treatment is begun, the eye is generall) de- stroyed, asthe repeated and violent vomiting cause a great determination of blood to the head and eyes, and increase of the inflamma- tion ; an effect which the opiates, given for the relief of the vomiting, also tend to pro- duce Beer has seen two cases in which the eye was pricked with a needle n-ar the insertion of the external straight muscle into the scle- rotica ; in both instances, the punctures were so small, that they w r ould scarcely have been found, had not the patients know n their situation exactly by the pain, and they were then only perceptible w ith a magnify- ing glass. The punctures were soon follow- ed by a convulsive rolling of the eyeball, and afterward by trismus, which continued severe in one patient a day and a half, and in another two days, but yielded to large doses of musk and opium given at short intervals, the warm bath, and the applica- tion of warm poultices containing byos- ciamus. As chymical injuries of. the eye produce an actual loss of substance, they are even more serious than common mechanical lesions. However, chymical injuries of little extent are generally repaired with tolerable facility and expedition. Quietude of the organ, and moderating the outward noxious effects by lukewarm mucilaginous applications, eithf r in the form of fomenta- tions, or eye waters, are the only requisite measures. If the cornea itself be hurt, as frequently happens w hen boiling hot fluids strike the eye, a kind of vesicle arises on the injured part, which becomes more and more white. The vesicle either bursts of itself, or subsides without breaking. In both cases, the production of the conjunc- tiva, of which the cyst of the vesicle is composed, shrivels up, and peels off, a new membrane of a similar nature being regene- rated underneath. An opaque speck is fre- quently apprehended 5 but, says Beer, it the surgeon will merely avoid being too much in a hurry to open the vesicle, and not disturb the work of nature by applying various remedies to the eye, there will be no danger of such an occurrence. More extensive chymical injuries of the «ye, which at first are not in themselves very severe, frequently become dangerous, in consequence of care not being taken to prevent the influence of external stimuli. To this class of cases belongs the accidental sprinkling of the eve with boiling fluids, or Vor. If. ‘ 39 general. While this author apjwove.s of cutting away any substance which is dead and partially detached, he strongly cau- tio.s surgeons not to remove the thin layer of the conjunctiva, nor to puncture any vesicle which may form. When the burning or corrosion is not limited to the conjunctiva of the eyeball, but extends to the lining of one or both eye- lids, Beer recommends covering the injured parts with mucilaginous applications, and mildly astringent ointments, containing tutty, or the white oxide of lead. In these cases, keeping the eye perfectly motionless must be hurtful, as it tends to promote the formation of adhesions, either between the eye and eyelids, (Symblepharon) or be- tween the eyelids themselves. (Ancbylo- blepharon.) Extensive, deeply penetrating, chymical injuries of the eyeball. Beer -describes as being almost always followed by more or less impairment of the functions of the organ, or of some of its particular textures, because such accidents never happen w ith- out a loss of substance. Thus a part, or the whole, of the cornea may be entirely de- stroyed, as in injuries caused by quicklime ; and, frequently, adhesions between the eye and eyelids, or betw een the tw o latter parts, cannot be prevented by any kind of skill. {Beer.) These serious degrees of mischief, as the same author observes, are mostly occasioned by slaked or unslaked lime, con- centrated mineral acids, fire, he. Unslaked lime, especially when extensively diffused over the eye by the immediate application of w ater, not unfrequently produces a sud- den destruction of the whole of the cornea, which is changed into a grayish, pappy sub- stance, capable of being removed from the subjacent iris with a camel-hair pencil. Such an annihilation of texture, however, is generally restricted to particular points, or the surface of the cornea. Wherever this membrane has been so much decom- posed, that a manifest depression is directly perceptible in it when inspected sidewrays, a snow-white shining speck must be expect- ed to be the consequence. Slaked lime never operates upon the cornea with so much violence, usually causing (as Beer states) only a superficial corrosion, or a coagulation of the lymph between the layers of the cornea. Nor are mineral acids, even when concentrated, genera! ly so de- structive to the cornea as qu'cklime; first, because, as fluids, they do not long remain in contact with the eye ; and secondly, be- cause the immediate mixture of the tears with them weakenstheir operation ; whereas it only increases that of unsiaked lime. Tfce local treatment here consists in carefully removing every particle of the hurtful sub- stance, afterward dropping frequently into OFHTHALUfir M the eye lukewarm mucilaginous decoctions or collyrin, or covering the injured place with a mild cerate, and excluding the air and light from the eye. Every endea- vour must also be made to prevent the formation of adhesions between the injured surfaces. In very severe burns of the eyeball, of course, all idea of restoring its functions is out of the question i he violence of the in- jury is the greater, the more numerous the vesicles are upon the conjunctiva, and the more the eyeball and the iris are incapable of motion. Here the only indication is to moderate the inflammation, and avert such additional mischief, as might otherwise be produced by it. With this view, the eye should be kept at rest, and excluded from the light and air. According to Beer, the most common injuries of the eye, partaking both of a mechanical and chymical nature, are those caused by mortar, or the accidental touching the eye with hot curling irons. When the mortar contains no particles of quicklime, it often occasions, at particular points of the cornea, very white specks, which Beer describes as being composed of coagulated lymph, and admitting of disper- sion. He even declares, that when the whole of the cornea is in this state, its trans- parency may be restored by_ proper treat- ment, as has been frequently exemplified to the gentlemen attending his clinical lectures. (B. i,p. 234.) The pricking of the eyeball with a red-hot needle, and the stinging of i by bees, wasps, and other insects, are also both chymical and mechanical injuries. Whether the sting be left in the skin of the eyelid, or in the conjunctiva, or not, a considerable inflammatory swelling immedi- ately takes place ; and, if the sting be lodged, and not now taken away, the inflamma- tion spreads, and the eye itself is endangered. In two eases, where the stings of bees were left in the skin of the upper eyelid, Beer has known gangrene arise in the short space of a day and a half, and the patients were saved with great difficulty. The treatment of such cases consists in immediately ex- tracting the sting, if lodged, and applying folds of linen over the eye, wet with cold water. After noticing the destructive effects of burning substances, the explosion of gun- powder, and fulminating silver on the eve, (cases in which, when the functions of the organ are annihilated, the only indication is to diminish the subsequent infiammat o:: and its consequences,) Boer inquires, what is the reason why the slightest mechanical, or chymical, injuries of the eye, in an appa- rently healthy subject, are sometimes fol- lowed by an immoderate degree of inflam- mation, and even the loss of the organ from suppuration ? It is, says he, an observation made by Schmidt, that there are some eyes, which the greatest bunglers may abuse for hours at a time, without being spoiled, their powerful organization defying all such un- skilful disturbance ; while other eyes are met with, which the most skilful opera- tors can hardly touch, without inducing a*, destructive degree of inflammation and sup- puration. It was to this peculiar idiosyn- crasy that Schmidt applied the tevm vulnera- bility ( Verwundharkeit.) Patients of this habit are said to possess an exceedingly fine soft skin, with a reddish polish upon it, and their cheeks are not only red, but exhibit a net- work of very minute vessels, which seem as if injected. Such individuals appear as if they were in the bloom of health ; and, says B er, in some respects they are really so. When their spirits are raised by the slightest causes, their complexion is universally red- dened ; but the least fear turns them as pale as a corpse. Their skin is described as being uncommonly irritable, sensible of every im- pression. and attacked wiih an erysipelatous redness, whenever any fatty substance touch- es it. In such habits, the utmost caution is necessary whenever the eyes have been in- jured, and the prognosis should be reserved. And, when an operation is to be done on their eyes, Beer recommends the previous exhibition of opium, and the application of a blister to some part of the skin, at a consi- derable distance from them. As a prophy- lactic measure, he also directs regular fric- tion of the surface of the body. In severe ophthalmies, particularly those which affect the eyeball itself, all mental emotions, anger, joy, &,c. should be avoided. Hence, no talkative nor quarrelsome per- sons should be suffered to remain with the patient; and noisy childien ought to be kept away from him. The apartment should be ventilated at least once a day, without the patient being exposed to any current of w ind. All touching of the eye, or rubbing it with the bed-clothes during sleep, must be strictly prohibited. Stimulating, spicy food, spiritu- ous drinks, and great bodily exercise are like- wise to b>- forbidden. In the list of things which have a hurtful effect, Beer also in- cludes all exertions of the lungs, every kind of disturbance, an atmosphere impregnated with tubacco-smoke, &.c. Having fulfilled the first general indication by removing, if possible, every kind of irrita- tion acting upon the eye, the second central in- dication specified by Beeras proper in the first stage of ophthalmy, is to be observed, which is to moderate , according to Ifv degree of in- flammation, the agem y of several things to the effect of which, the organ is naturally subjected. Thus, the inflamed eye should not be exer- cised, even though the eyeball itself may not be immediately inflamed ; and the operation of the light and air should be diminished partly by green silk eye-shades, and partly by window blinds. Attention to this rule is still more necessary, when the eyeball itself is affected. With respect to the exclu- sion of light, it is to be well remembered, that it is only adviseable, as Dr. Vetch observes, in the very early stage of inflam- mation, the eye becoming more irritable and less manageable, w! en the access of a moderate degree of light is afterward pre- vented. ( Vetch on Diseases of the lyc, p. lb.) The third general indication , mentioned OPHTHALMY. 307 by Beer, as proper in tbe first stage of ophthalmy, when the disorder threatens to extend to the whole organ, and to bring on a febrile disturbance of the system, is to counteract these effects by covering the eye with folded linen wet with simple cold water, or vinegar and water; and having recourse to leeches, or when the nature of the case allows, to scarifications (B. 1 , p. 242.) Here, however, it merits particular notice, that, Beer, in expressing a general preference to cold lotions in the first stage of ophthalmy, differs from Richter, Scarpa, and Mr. Travers, ( Synopsis of the Diseases of the Eye,p . 250,) all of whom, in the painfully acute stage, recommend tepid emollieut ap- plications. With regard to leeches, also, the late Mr. Ware objected to their being put on, or very near the e) elids, as they sometimes cause a cons.derable swelling of these parts, and increase, instead of lessening the irritation. In ordinary cases, his method was to apply three on the temple, about an inch and a half from the outer part of the orbit. Scarpa recommends applying the leeches to the vicinity of the eyelids, especially about the inner canthus, on the vena angularis, where it joins the frontal, deep orbitar, and transverse vein of the face. Beer prefers nearly the same situation, as that»specified by Scarpa, viz. the inner canthus, immediately below the under eyelid ; and he forbids the application of leeches above either canthus, as likely to produce a disagreeable ecchy mods in the cellular membrane of the upper eyelid. The number of leeches, and the time, which they should be allowed to suck, he thinks, ought to depend upon the severity of the inflammation. According to Beer, when this mode of bleeding is to be of any service, the patient will experience a considerable abatement of the throbbing pain, tension, &c. in the affected eye. Hence, when any of the leeches fall off prematurely, the bleeding from the bites is to be kept up, with a sponge dipped in warm water, until such relief is felt. In the acute stage, Beer considers the abstraction of blood by means of scarifica- tions rarely admissible. (B. \,p. 243.) Mr. Travers also sets down scarifications of the conjunctiva as mostly objectionable in the acute stage ; though highly beneficial in the chronic, where the lining of the eyelids is thickened and over vascular; and a con- siderable discharge of blood may be thus obtained, if the operation be briskly done With a sharp lancet, and the lower lid kept everted, and fomented. The same gentle- man states, that cupping has a decided supe- riority over leeches, but that both are well adapted to relieve local congestion. Yet, he deems these methods too indirect to answer as substitutes for the lancet, where it is de- sirable to make the system “ sustain and feel a reduction of power,” in which case blood must betaken from a vein, or the temporal artery. ( Synopsis , fyc. p. 249.) While inflam- mation of the conjunctiva is described by Dr Vetch, as not much affected by bleeding, unless the Quantity of blood taken away be such as to occasion syncope, he states, that the abstraction of blood, in quantities pro- portioned to the violence of the symptoms, more especially, by means of cupping and leeches, has for the most part sufficient con- trol over the various states and individual symptoms of sclerotic inflammation. In some obscure cases of what this author terms amaurotic inflammation, he has seen great benefit derived from the application of leeches to the septum nasi, and he represents their being put directly on ihe conjunctival li .ing of the eyelids, as being sometimes more advantageous than on the adjacent integuments the orifices bleeding with great freedom. (On Diseases of the Eye,p 15.) If some of the above remarks are correct, scarifications are rather too boldly praised by the late Mr. Ware, as applicable to the acute stage of ophthalmy. But, supposing the first violence of the attack past, his re- commendation of the practice either in the vascular and turgid state of the lining of the eyelids, or in the eversion of the lower one from a similar cause, seems perfectly unob- jectionable. When the upper eyelid was very cedematous, and its thickness prevented the application of proper remedies to the eye, Mr. Ware also thought a few punctures near the cilite useful, by causing a discharge of bloody serum, and a quick subsidence of the swelling. And he speaks of the excision of a piece of the excessively tumid lining of each eyelid, in cases of ophthalmy with ev ersion, as having afforded ; reat and speedy relief. (Ware on Ophthalmy. fyc. p. 39 ) The fourth general indication , enumerated by Beer, is that, which has for its objects a diet and reirimen suited to the state of the case, after it has attained a degree, in which its effects begin to be felt throughout the system. When therefore the plan is to be rigorously practised, the patient’s ordinary diet is to be reduced, and he is to be allowed only vegetable food, cooling drinks, water, weak lemonade &.c. And not merely the eye itself is to be kept at rest, but the whole body. Should the disorder be further advanced, and attended with a great deal of inflamma- tory fever, the observance of the foregoing indications will not suffice for checking the inflammation and preventing suppuration, unless the fifth indication, laid down by Beer, be fulfilled, which is to employ suck remedies as operate upon the whole constitution, 1 Purgative and gently aperient medicines, which will empty the bowels well, and lessen the determination of blood to the head and eyes. 2. Clysters, which are useful on the same principles. 3. The frequent exhibition of the nitras potassee. 4. General bleeding, the efficacy of which will much depend upon the blood being voided in a full stream. Beer seems to prefer opening a vein on the foot ; but, in England, the most experienced practitioners generally open a vein in the arm, and sometimes the temporal artery. The blood, as Beer remarks, should be allow- ed to flow until the hard small pulse rises and becomes plainly softer;- for, otherwise tho OPHTHALMT. am operation will be completely useless. Also, when in these cases, general bleeding is no longer indicated, the employment of leeches will yet be advantageous, and afterward, sca- rifications may be practised, which, at any earlier period, would have aggravated all the inflammatory symptoms. By strict attention to the five above ex- pl lined indications, either without precipita- tion. or too much delay, the first stage of opVhalmy, even when in its most violent degree, may be certainly checked and re- solved ; and all suppuration avoided, so that the eye may be restored to a perfectly sound state again, provided the patient, previously to the attack, was quite healthy, and of course the affection of the eye a genuine idiopathic inflammation. {Beer, B. 1. p. 246, 247.) Respecting the prognosis and indications in the second stage of ophthalmy in general, and of idiopathic cases in particular, Beer offers many interesting remarks. He observes, that when ophthalmy has reached its second stage, which may be known by circum- stances already referred to in the preceding columns, it must be clear, that the above indications are no longer valid, and the ful- filment of them would destroy the eye. In the second stage, every thing yv hich has a tendency to produce further weakness of the eye must be avoided, or suppuration will be the consequence : the first indication, therefore, specified by Beer, is to let the eye he cautiously exposed according as its tendency will allow , to its wonted stimuli again. 1. By letting fresh, dry, and, if possible, a warmish air, have free access to the organ. 2. By exposing the eye to as much light (not of a reflected description) as can be borne, not only without difficulty, but with pleasure, 3. By moderately exercising the organ, especially in the inspection of agreeable diversified objects ; a plan, which is of infi- nite service, when the eyeball itself has been affected. The second indication, proposed by Beer in the second stage of ophthalmy in general, is to apply tonic remedies, particularly those of a volatile kind, to the eye, which are to be dis- continued in the event of suppuration. 1. Beer praises the application of well-warmed linen compresses, which, if necessary, may be sprinkled with camphor ; or, in urgent cases, he uses little bags of aromatic herbs and camphor ; a practice, in which I am disposed to think surgeons here will have little or no confidence 2. However, when the eye is too irritable to bear the applica- tion of bags of aromatic substances, Beer sanctions the employment of poultices nude of bread crum and warm herbs, or the pulp of a roasted apple. But, this experienced author is very particular in qualifying his approbation of moist applications with a caution, that they must never be allowed to become completely cold on the eye, where- by they would do more harm in a quarter of an hour, than any good, which may have been attained in many hours by their pre- vious use. Hence, Beer employs poultices only in cases of necessity. In this country, “ when the extreme vascular congestion and excessive sensibility are reduced, and the inflammation tends to become chronic, the U3c of cold lotions, of a slightly ton c quality, is substituted with great advantage for ablu- tions of warm water. The sulphates of alum and zinc are the best.” {Tracers, Sy- nopsis, tyc. p. 252.) The employment of astringents also agrees with the advice delivered by Richter and Scarpa. Here then we find a point on which Beer differs from the generality of writers ; but, nothing is clearer to me, than that his alarm about the ill effect of cold upon the eye in the second stage of ophthalmy is only the fruit of some theories, which he entertains, and not of impartial experience 3. When there are small ulcers, or pustules, on the eyeball itself, Beer assures us, that great benefit is derived from dropping between it and the eyelids a tepid solution of the lapis divinus, the composition of which is elsewhere des- cribed (see Lachrymal Organs,) and bathing the eye with the same application, to which a little of the vinous tincture of opium is added. Should this remedy fail in checking the progress of the ulcers, or pustules, Beer reeommends the addition of acetate of lead. 4. And, says the same author, when no deci- ded amendment is produced, within twenty- four hours, the suppurating points must be touched once or twice a day, according to the urgency of the danger, with a camel-hair pencil, dipped either in a watery solution of opium, or the vinous tincture of opium. In the worst cases, he even directs Hoffman’s balsam, vitas, naphtha, or the Peruvian balsam to be mixed with the vinous tincture of opium. But, Beer observes, that when these reme- dies have been too precipitately employed, and any granulations, or excrescences form, the treatment must be less active, and then these new productions will frequently recede of themselves ; but, if they should not do so, they may be removed with burnt alum, or caustic. {B. I, p.252.) The third-rule, laid down by Beer, in the treatment of the second stage of ophthalmy , cautions the practitioner not to apply the caustic or the knife, to any of the morbid changes, which either originate during the first stage, and continue in the second, or make their first appearance at the period of suppuration, as, for instance, opacities of the cornea, eversion of one or both eyelids, &c. However, as exceptions to this advice, Beer adverts to the treatment of new-growths under the circumstances above specified, and to that of abscesses of the eyeball, where the matter is of an unhealthy quality, and so copious as to make an opening ad\ iseable, which practice, however, as a general one, he condemns. The other morbid changes, already alluded to, the practitioner must endeavour to remove simply by proper treat- ment of the second stage. {Beer, B. 1, p. 254.) Beer’s fourth rule in the treatment of the seebnd stage of ophthalmy in general, and of OPHTHALM-l . J0i> idiopathic ophthalmy in particular, when the suppurative process is extending itself, and threatening to impair the health, is, 1st. To allow the patient such food as is both easy of digestion, and of a very nutritious quality, and even a moderate quantity of wine and spirituous drinks, if he h s been accustomed to them. 2dly. To direct the patient to keep his eye exposed the greater part of the day, in a fresh, dry, and (if possible) mild air, and take just exercise enough in various ways to p'roduce a slight degree of fatigue. 3dly. When the eye itself is affected with suppura tion, and the sight is either thereby much impaired, or quite lost, and, of course, the patient very unhappy and depressed, Beer considers it highly beneficial to let his spirits be improved by society. The fifth rule , or, general indication in the second stage , laid down by Beer, refers to the necessity of supporting the constitution, when the suppurative process is attended with a general febrile disturbance. For this purpose, he recommends, 1st. The exhibition of calamus aromaticus, naphtha, and cam phor. 2dly. If they prove ineffectual alone, they are to be joined with other tonics, espe- cially bark. 3dly. The warm bath, which, in consequence of the sympathy between the skin and eyes, is particularly efficacious. 4thly. Rubefacients, applied not far from the eye ; means, which are exceedingly bene- ficial in the second stage of ophthalmy. ( B . P-257.) As an appendix to these general remarks, delivered by Beer, on the general treatment of ophthalmy in its first and second stages, I annex the sentiments of some other writers, as either confirming, or rendering question- able, some of his statements. According to Scarpa, when bleeding and other evacuations have been practised, the next most useful measure is the application of a blister to the nape of the neck. He ob- serves, that the skin here and behind the ears, has a stronger sympathy with the eyes, than any other part of the integuments. On the other hand, the late Mr. Ware pre- ferred blistering the temples, and says, “ When the leeches have fallen off, and the consequent hemorrhage has ceased, I would advise a blister of the size of half a crown to be applied on the temples, directly over the orifices made by the leeches, and I have found, that the sooner the blister has followed th • b feeding , the more efficacious both have proved .” He adds, that when ophthalmy is very violent, and resists common methods, the most beneficial effects are sometimes produced by the application of a blister large enough to cover the whole head. ( P . 43, 44.) With respect to blisters, another modern writer particularly objects to their being applied near the eye, or on the temples, ‘ l where they never fail to prove injurious.” There is (says he) “ but one exception to this, as a general rule ; for, it would seem, that blisters applied to the external surface of the palpebra, in cases of purulent ophthal- mia, tend considerably to diminish the pum- lency and chemosis.” ( Vetch on Diseases of the Eye,p. 17.) In the second stage of acute ophthalmy, the vinous tincture of opium (the tinctura thebaica) has been very extensively used, as a topical application. In common cases, two or three drop- may be insinuated be- tween the eyelids and globe of the eye? twice a day ; but, in other instances, attended with more sensibility, once at first will be suffi- cient The late Mr. Ware, who brought this application into great repute, found, that in- troducing two, or three drops, of this medi- cine at the inner canthus, and letting them glide gradually over the eye, by gently drawing down the lower eyelid, proved equally beneficial, and less painful than letting them fall directly upon the eyeball. Immediately the application is made, it usu- ally creates a copious flow of tears, a smart- ing, and a sense of heat in the eyes ; which inconveniences, however, soon cease, and the eyes become clearer, and feel decidedly improved. But, notwithstanding every ex- aggeration, unbiassed surgeons are now fully convinced, that the vinous tincture of opium is a proper application only when the in- flammatory action has been previously di- minished by bloodletting, aperient medi- cines, and blisters, and when the action of the vessels has been weakened by the con- tinuance of the disease. Nor is any doubt entertained, that the late Mr. Ware went much too far, when he recommended the vinous tincture of opium, as a most effectual application in every species and stage of the disorder, from the most mild and recent to the most obstinate and inveterate. (P, 51.' Scarpa has seen the necessity of limiting the use of the remedy in question, and has expressly pointed out, that it is useful only when the violence of the pain, and the aversion to light, have abated. Indeed, Mr. Ware himself, a little before sanctioning its employment in all cases, has acknowledged, that, in certain instances, in which the com- plaint is generally recent, the eyes appear shining and glossy, and feel exquisite pain on exposure to the light, no relief at all was obtained. (P 48, 49.) Mr. Travers has re- marked, that “ there are inflammations, which assume a chronic character in their commencement, evidently depending on a state of atony, of very partial extent, void of pain, and scarcely possessing any sign of inflammation, except the congestion of the vessels, or, if any, so feebly marked, as to encourage us to disregard them in the treat- ment. in such cases, a single stimulus will often restore the healthy action at once. The vinous tincture of opium has acquired a nostrum-!ike importance from its restora- tive operation in such casas ; a virtue, I be - lieve, not proper to it. A drop or two of the zinc, or the lunar caustic solution, or water impregnated with calomel, or a minute portion of the citrine ointment, or any other stimulant, would do as much.” ( Synopsis , fyc. p. 252.) Whenever the patient can easily bear a moderate degree of light, Scarpa directs all orHTHALMY. aiy coverings to be removed irom the eyes, ex- cept a shade of green, or black silk. A brighter light should be gradually admitted into the chamber every day, so that the eyes may become habituated, as soon as possible, to the open daylight ; for, as Scarpa truly states, nothing has a greater tendency to pro- long and increase the morbid irritability of the eyes than keeping them unnecessarily long in a dark situation, or covered with compresses and bandages. Dr. Vetch has such a dislike to the plan of covering the eye, that he never suffers a shade to be worn, conceiving that, in con- junctival inflammation, it always does a great deal of harm by preventing a free exposure of the eye to a temperate atmosphere. (On Diseases of the Eye,p 17.) Besides the common remedies for inflam- mation, there are some very powerful means, which may be employed for the re- lief of particular state* of ophthalmy with great effect. Thus, as the latter author has observed, by means of hysoscinmus, bella- donna, and stramonium, (See Belladonna) the important structure of the iris may be secured from injury, at the same time that other measures are adopted for checking the inflammation. Such medicines may even be applied, as a mechanical force, for de- taching any recent adhesion. (Op. cit.p. 18.) The uses of the argentum nitratum are also very extensive : “the slightest applica- tion of it in substance (says D . Vetch) can often remove the highest degree of morbid sensibility to light, and instantaneously re- store quietude to the organ; it can prevent incipient changes, and obviate advanced ones; and may also be used io solution, as a valuable sedative.” The mention of so stimulating and active a substance as the nitrate of silver having a .sedative effect may excite surprise ; but the fact is unquestionable, and well illustrated in the treatment of several diseases. (See Cornea and Iris.) As another modern writer correctly states, it is remarkable that even the weaker forms of medicated lotions irri- tate, and none more than such as contain opium. Tlie relief, afforded by anodyne fomentations in general, is very various. “ I have known them (says Mr. Travel-*) ob- jected to as painful, and patients inquire if they might not substitute warm water tor the aqueous solution of opium and infusions of poppy and hemlock. The same observa- tion applies especially to painful herpetic cutaneous affections, and acutely irritable ulcers. Upon these a solution of opium often acts as a stimulant, and augments pain, while the lunar caustic solution as often as- suages it.” At the same time, Mr. Travers admit*, that exceptions occur, and that lie has met with case-, “ in which no other ap- plication than the aqueous solution of opium could be borne.” He has also known the vapour of laudanum afford the most marked relief to the irritability to light accomtmny ing strumous opVhahny. ( Synopsis of the Diseases of the Eye, p. 251.) .According to Dr. Vetch, it is impossible, in cases of conjunctiva! ophthalmia, to poj sess an application of greater efficacy, than the undiluted liquor plumbi subacetaii-, for altering the morbid and purulent state of that membrane; he also describes iico tiana. externally employed as a n r otic and astringent, as being of singular service in lessening the pain, and turnelaction. (P. 19.) However, the discordance among the best writers, about the effects of favourite local applications, would lead me to enjoin rather attention to the leading principles of*the treatment, than confidence in the superior efficacy of any particular drug or composi- tion. As also the local applications should vary in the different stages of purulent ophthalmy, no single one will always be right, li Bper had d -livercd no observa- tions of greater importance, than his con- demnation of Bates’s camphorated lotion, and liis praise of other styptic stimulating applications, his remarks would be of little value ; but, as he has pointed out the differ- ent stages of purulent ophthalmia in a very correct manner, and adapted his remedies to these various states of the disease, his infor- mation comprehends scientific principles, and becomes peculiarly interesting. The same praise belongs also to Dr. Vetch’s ob- servations on purulent ophthalmy, who in some points, both of the description of the complaint and its treatment, has surpass- ed Beer. Of the different Kinds of Ophthalmy . Beer’s classification is very comp enensive. According to the situations, in which oph- thalmic iufiaminatio first originates, he pro- poses a general division ot it into three (qrms, as suggested. bv some of the older writers; viz inflammation of the eyelids , or blepha- rophthalmitis ; inflammation of the parts between the orbit and globe of the eye ; and, lastly, inflammation of the eyeball itself or ophthalmitis. He observes, however, mat these distinctions seem to assign a considera- ble extent to the original seal of th<- aff ct ion ; for the expression, inflammation of the. eye- lids, can only denote a case, in winch the disorder begins at once in all the parts com- posing the eyelids. In the same way, inflam- mation of the parts between the eysbull and orbit appears to signifv, that all those parts constitute the original sphere of th** com- plaint; while inflammation of the eyeball seems to denote that the disorder has begun at once in all the textures, of which this organ is composed. But, fortunately, as Beer remarks, the extent of the original seat of genuine idiopathic inflammation of the eye is but seldom thus considerable ; being mostly restricted to particular textures, from which it first spreads further only when neglected, or injudiciously treated. Hence, certain subdivisions of the complaint are necessary ; and. accordingly, Beer subdivides inflammation of the eyelids , first, into the erysipelatous , or blepharophthalmilis erysipc - latosa , which commences in the integuments oi these parts. Secondly, into that, which originates at the edges of the pulpebrai, in the conjunctiva lining these parts, and tbc OPIlTlIAUn Meibomian glands, and which Beer denomi- nates glandular inflammation of the eyelid s or blepkarophthalrnitis glandulusa ; a case, described by writers under an infinite num- ber of names, and often confounded with complaints of a totally different nature. Thirdly, when the eff ets of the inflamma- tion ar * confined to a -mall portion of the eyelid it rnn-ti«ute» the disease, termed the inflammatory stye, or hordeolum, which Beer say-- is larely a simple inflammation, but complicated with a scrofulous habit ; a pro- position, which, I think, will not receive any credit in England. Fourthly, as there is one more form of inflammation of the eyelids. Beer xives it the name of the erysipelatous swelling of the cornea of the eye, or anchy- lups erysiptlalosa , which affects the skin of the inner canthus, immediately over the lachrymal sac. The name, here suggested, expresses precisely the seat of the inflamma- tion, and, as Beer thinks, will tend to prevent the case from being mistaken for inflamma- tion of the lachrymal sac. Inflammation of the parts in the orbit comprehends, first, in- flammation of the lachrymal gland ; secondly, inflammation of the lachrymal sac, a disorder, which begins in the lachrymal sac and nasal duct, and generally extends with great ra- pidity over all the excreting parts of the la- chrymal organs ; and, thirdly, influrn "'’on of the caruncula lachrymalis, or the erica, this inflammetoria. I; the Same way, inflammations of tl eyeball a lini' of a classification, which is of the high .-t practical importance^ first, into the erysipelatous inflammation of the sclerotic conjunctiva , the ophthalmitis erysipelatosa, which denotes that torm of the disorder, which is first entirely confined to the mem- brane connecting together the eyelids and eyeball. Secondly, into inflammation of the outer textures of the eyeball , the ophthalmitis externa , originating in the cornea and sclero- tica. Thirdly, into inflammation of the in- nermost textures of the eyeball, the ophthal- mitis interna , which has two forms highly necessary to be recollected in practice; for the inflammation may begin immediately in the retina ehoroides, the membrane of vi- treous humour, &ic. and spread from these textures t<> all the rest of the eyeball, being n ined true internal inflammation of the eye- ball, or ophthalmitis interna vera, and thus discriminated from another case, which is originally seated in the iris, the adjoining corpus ciliare, the lens, and its capsule, and afterward extends from these parts to the more deeply situated coats, and to the texture of t lie vitreous humour. This last form of internal inflammation of the eyeball is named both by Schmidt und Beer, iritis. The clas- sification then embraces a view of the dif- ferent form 5 of ophthalmy, as modified by constitutional causes, as the effect of con- tagious and infectious diseases, measles, small-pox, &c. ; and as a complication of eeriain cachexia;, like gout, rheumatism, and scurvy. Although I have thus given a brief deline- ation of Beer’s classification of ophthalmic inflammation?, it Is not my design in the sub- sequent columns, to enter into a full consi- deration of every particular case, above enumerated ; first, because the limits of this work will not permit me to do so; and se- condly, because some of these cases have been already considered in other parts of the work. (6ee Lachrymal Organs.) Common Inflammation of the Eyelids. This form of disease is said by Beer to affect the upper much more frequently, than the lower eyelid, because the former obviously has a larger surface exposed to injuries from without ; nor does the complaint always spread to the latter. From the margin of the eyelid, a very red, tense, painful swelling arises, attended with heat, throbbing, and a great deal of tenderness, when touched. It gradually extends over the whole eyelid : but seems to be plainly bounded by the edge of the orbit. The motion of the eyelid is always more or less obstructed, and, at length, when the inflammation has reached its greatest degree, it is completely prevent- ed. Nor is there any difficulty in compre- hending why, when tiie inflammation has become severe, the eye should he excessively dry, and every attempt on the part of the patient to move the eyelid should be produc- tive of considerable pain, and of a sensation, ns if some sharp extraneous substances lay under the lid ; for at this period, the palpe- bral conjunctiva is already severely inflamed, and, consequently, the secretion of mucus from the Meibomian giands is immediately stopped by the inflammation itself, while that of the tears is interrupted partly by the ex- tension of the inflammation to the sclerotic conjunctiva, and partly by the effect of the sympathetic connexion existing between the conjunctiva of the eyelid, and that of the eyeball. To this last cause, viz. sympathy. Beer refers the supervening dryness and shri- velling up of the lachrymal papilla;, as well as the apparent closure of the puncta lachry- rnalia, and the uneasy dry state of the edgvs of the eyelids. Hence, also, the dry- ness of the adjacent nostril, and a very disa- greeable smell of dust obliging the patient to sneeze repeatedly, w hich act is constantly attended with a great increase of pain in the swelling, a transient shooting of it to the eye and bead, and a sensation as if flashes of light we e elicited within the eyeball; a kind of hallucination, technically named photopsia. As the original seat of the in- flammation is already extensive, one may readily understand, says Beer, why the affec- tion in its first stage, particularly when neglected, or badly treated, should frequently give rise to some febrile disturbance of the system. In the second stage of the case, or that of suppuration, which billows when the inflam- mation is violent and not soon dispersed, matter forms with the annexed train of -ymptoms. The redness suddenly increases very much, the eyelid becoming of a brown* i-b red, and lastly of a purplish red colour. The swelling becomes more prominent, and present? a conical eminence, either in the OPHTHALMV 3J.2 middle of the eyelid, or close to the outer or inner canthus. The pain is irregular, and of a stinging, burning kind, a throbbing being felt only in the deeper part of the tumour. At length, the swelling becomes somewhat softer, and Ies9 sensible at its most projecting point. The secretion from th<* Meibomian and lachrymal glands, which in the first stage of the disorder was suppress* d, is now quite re-established, but more copiously, than in the healthy state. During sleep, a quantity of mucus accumulates between the edges of the eyes, and glues them together. An ex- traordinary sensation of cold and heaviness is felt all about the eye. Ultimately the most prominent point of the swelling presents a pale red colour, followed by a yellowish livid tinge. As the abscess is now com- pletely formed, the fluctuation of the matter can be plainly felt. (Beer, B. 1 ,p. 269, fyc ) According to the same author, nothing very particular is known respecting the causes of the preceding form of ophthalmic inflammation, and, with the exception of blows, he has not been able to discover the precise circumstances which give rise to it. With regard to the prognosis, if the treat- ment be neglected, or injudicious, the in- flammation may suddenly become so violent, as to produce in weak subjects gangrenous mischief. But, when the case is properly managed in its first stage, the second, or that of suppuration, never ensues; yet, says Beer, the curative measures must be decisive, and valuable time not wasted on trifling means, although due regard must be paid to the constitution. When the inflammation subsides favourably, it le -ves no vestiges of it behind, and even the redness, which is the latest in disappearing, completely goes off in a few days, and the function of the eyelid becomes perfect again. If gangrene and sloughing take place, the outer coverings of the eyelid are destroyed, and the consequences are an incurable eversion of the part. (S eo Ectr opium) ora hare-eye, (see Lagophihalmus.) When suppuration happens favourably, the abscess sometimes breaks very well of itself on the upper eyelid; but, according to Beer, this does not readily occur on the lower one, nor without the formation of sinuses, which sometimes run quite into the orbit. After the abscess has burst, or been opened, the part heals up with great celerity in favour- able constitutions, but slowly in others ; vermilion granulations arise from the bot- tom of the cavity, and a cicatrix follows which is scarcely perceptible. When the abscess is very large, however, and bursts of itself, the upper eyelid continues for some time very much weakened. If the collec- tion of matter be neglected, or wrongly treated, or the subject be unhealthy, or the disease be aggravated by the etFects of a damp atmosphere, hurtful food, severe mental trouble, wet poultices, or too long confinement of the matter, then, says Beer, fistulae are apt to be produced, sometimes complicated with necrosis of the,bone, the certain effects of which are some perma- nent and mostly incurable disease of the eyelid, and impairment of its functions : 1st. A closure of the lachrymal canals, with a permanent stiilicidium. 2. A complete obliteration of the same lubes, with an in- curable stiilicidium- 3. A prolapsus of the upper eyelid, from distention of the skin by the long confinement of the matter. 4. Inversion of the edge of the eyelid, from a shrinking of its cartilage. 5. Eversion of the eyelid, and hare-eye, from loss <»f kin. (Beer.) As, in this species of inflammation, says the same author, the organ of sight cannot well be affected, unless the disorder after- ward extend itself very much, the exclusion of air and light is here but of little use Linen compresses, well wet with very cold water, or vinegar and water, are to be ap- plied ; and, while the complaint is local, leeches are to be used ; but, if the constitu- tion be threatened with febrile symptoms, then Beer urges the necessity of venesec- tion, low diet, purgatives, and general antiphlogistic measures. (B. \,p. 275.) In the second stage, with the exception of a few points, Beer states, that the case is to be treated like any other common abscess. When the matter is situated in the middle of the upper eyelid, not far beneath the skin, the abscess may be allowed to burst of itself, especially, if the patient have a great dread of the knife. But, if the matter lie near the outer, or inner canthus, it should be let out w ith a lancet as soon as its fluctua- tion is quite distinct, the incision being made in the direction of the fibres of the orbicular muscle. When fistulae- or gan- grene, have already taken place, the treat- ment should be like that, which is applicable to the s;im* j kind of mischief in most other parts of the skin. Erysipelatous Inflammation of the Eyelids usually affects both these parts together, very seldom only the upper one, and never the lower alone. When also both are affected, the disorder always presents itself in the greatest degree in the upper eyelid A pale, yellowish red, seemingly transparent, shining swelling arises from the edges of the eyelids, and rapidly extends itself, without any determinate boundary, the faint red colour being gradually lost upon the eyebrow above, and not unfrequently upon the cheek below. When the inflamed part is gently touched, the redness disappears, but only for a moment. At length, (be swelling towards the margins of the eyelids becomes exceed- ingly soft, and feels like a vesicle that has been raised by a blistering plaster. The pain is inconsiderable, not attended with throbbing, but rather with a sense of heat and stiffness; when the part is slightly touched, the patient experiences a lancinating sensation in it. Its temperature is not much increased. The secretions from the Meibomian glands, lachrymal gland, and mucous membrane of the nostrils, are much augmented. — In a strong subject, the disorder, if genuine and idiopathic, is not productive of any constitutional disturbance '• but, in bad OPHTHALM\ 313 habits, and weak females and children, it is sometimes attended with fever. However, when the complaint partakes of the phleg- monous character, and is badly treated, the general symptoms are occasionally very se- vere at the change from the first to the second stage, and the case may then termi- nate in a gangrenous kind of suppuration. In irritable, delicate children, says Beer, when the disease spreads over the face, the case requires the most skilful treatment for the prevention of a disastrous termination. In sirong persons, the second stage of this disorder rarely ends in a manifest suppura- tion ; but there is rather an exudation of lymph, which becoming dry, forms very small, delicate, branny scales, in the com- position of which the desquamated cuticle has also a considerable share. In other instances, vesications of various sizes are formed on the erysipelatous surface, and burst, and discharge a fluid, which is con- verted into yellowish scabs. According to Beer, the skin of the eye- lids is particularly prone lo erysipelatous in- flammation, which is therefore more easily in- duced in it, than in the integuments of other parts. Beer considers the sudden effect of a cold blast of air, or of very cold water, upon the skin of the eyelid, while in a slate of free perspiration, as the most common cause of its being attacked with erysipelas, parti- cularly in weak subjects. He states, how- ever, that the complaint may be occasioned by the stings of bees, wasps, and other insects ; accidents, which when the stings are not extracted, are liable to be followed by a violent and dangerous general inflam- mation of the eyelid, not unfrequentiy extending in a perilous degree to the eyeball itself. (B. 1 , p. 281.) With regard to the prognosis, no other case of ophthalmic inflammation so fre- quently subsides without the aid of surgery as this, provided the constitution he healthy and strong; and, when the complaint is resolved in its first stage, the vestiges of it afterward are as little as those consequent to common inflammation of the eyelids. The second stage, however well treated, is followed fora long time by a peculiar sen- sibility of the skin to the impression of cold damp air, and a strong propensity to relapses. If, when the cuticle peels off, a patient of weak constitution sit in a current of damp cold air, or try to wash away the scales and scabs with cold water, Beer states, that an cedematous affection of the eyelid will be produced, which is often very obstinate, and apt to occasion a temporary inversion of the ciliae ( Trichiasis ,) or a similar state of the edge of the eyelid ( Entropium .) And, he observes, that when from neglect, or bad treatment, an erysipelatous inflamma- tion of the eyelid terminates in suppuration, the abscess is not like a common one, hut the matter rapidly makes its way out through several openings in the already partially disorganized skin, and, in general, this state is followed by ill-conditioned tedious ulce- rations, vvherebv a good deal of skin is Yol. IT 49 always destroyed. Under these circum- stances, all those consequences may be produced, which have been described as liable to take place from the second, or suppurative stage, of common inflammation of the eyelid. Gangrene and sloughing may even occur, when erysipelas of the eyelids is brought on hy the unremoved sting of an insect, and efficient treatment is delayed. The treatment, recommended by Beer in the first stage, consists in the application of cold water, and he remarks, that exposure of the part for a time to a cool, moist, hut, in other respects, pure atmosphere, will often suffice for the removal of the complaint. When, however, the disorder increases, and assumes a phlegmonous character, the direc- tions given for the treatment of blepharoph- thalmitis, are to be followed. In the second stage of erysipelas of the eyelids, Beer praises the good effects of a mild, dry air, of an equal temperature, and recommends covering the parts with a light bandage, under which are to be put well warmed linen compresses, which, for ‘weak persons, should be sprinkled with camphor ; or he directs the eyelids to be covered with hags of aromatic herbs; generally a very favourite plan with Beer, whenever he ob- jects to moist applications. In such indivi- duals, he observes, that the cure is promoted by keeping up the function of the skin with gentle diaphoretic medicines, with which, when the debility is very great, camphor should be joined. Should an abscess form, the same treatment is proper as in the se- cond stage of common inflammation of the eyelids, or (what Beer calls) blepharophthal- mitis. Glandular Inflammation of the Eyelids, or the Blephar ophthalmitis Glandulosa, as Beer terms it, is considered by this author as the disease, of which all the various cases of pu- rulent ophthalmy are only modifications, which he describes under the names of idio- pathic catarrhal ophthalmy ; idiopathic catar- rhal-rheumatic ophthalmy ; and blepharo-blen- norrhcen, or ophtlialmo-blennorhcea. The two latter terms comprehend the purulent oph- thalmy of infants, the Egyptian ophthalmy, the gonorrhoeal ophthalmy, &c. Glandular Inflammation of the Eyelids , Beer knew very well was so far a defective term, that it seemed to imply merely an af- fection of the Meibomian and mucous glands of those parts, whereas he means to express by this name the kind of inflammation, of which all the cases, usually called in this country purulent ophthalmies , are varieties and modifications, and in which the con- junctiva is also particularly affected. Acute suppurative inflammation of the con- junctiva, divisible into the mild and severe forms, as proposed by Mr. Travers, appears, perhaps, a better name ( Synopsis , fyc. p. 96, &c.) Dr. Vetch, who also prefers the gene- ral term conjunctival inflammation, observes, that from many internal and external causes, the membrane of the conjunctiva is liable to become the seat of inflammation, more especially that portion of it, which gives 314 ©phthalmy: a lining to\the inner surface of the eyelids. The disease, in its general nature, he says, differs little from that which is met with in other parts having a similar surface, as the nose, the fauces, the bronchial cells, and the urethra ; but, the continuation of the mem- brane forward upon the anterior portion of the eye, and the consequent liability of the inflammation to affect this important organ, attach much interest to all the circumstan- ces. capable of producing it. (Vetch on Diseases of the Eye,p. 148.) In the common glandular inflammation of the eyelids, des- cribed by Beer, which seems to me to cor- respond to the more moderate forms of purulent ophlhalmy met with in this country, either the whole, or pnly that part of the edges, which is near one, or both canthi, is affected with a very red, hardish, sensible swelling, attended with a violent annoying degree of itching. This swelling, Beer ob- serves, does riot extend far over the outside of the eyelid upwards, or downwards, at most, not more than a few lines ; but it spreads over the palpebral conjunctiva, es- pecially when neglected, or badly treated, and the constitution is w eak. This, he says, can only be discovered when the eyelid is everted. The further the swelling extends over the inside of the eyelid, the more is the motion of the part obstructed, not on account of any want of power in the orbi- cular muscle, but from the fear of the pain, with which every attempt to move the eyelid is accompanied. The itching, which continually distresses the patient, more or less, is often succeeded by an irritating, burning kind of pain, which is particularly experienced w ? hen the eyelids are moved, and hence, the patient is obliged, as it were, to keep his eye closed. While the inflam- mation is restricted to the edges and con junctiva of the eyelids, and the Meibomian glands situated under it. though the secretion from these glands is entirely stopped, that from the lachrymal gland is much augment- ed,, and consequently, the disease is- asso- ciated with a true epiphora , which is seri- ously aggravated whenever the eye is ex- posed to a strong light. As, under these circumstances, the tears are not properly blended with the Meibomian secretion, they must of course be very irritating to the eye and its surrounding parts, and less fitted for properly lubricating its surface. Hence, the pain now becomes burning, and not unfre quently the cheek, over which the tears run, is excoriated. As soon as the inflam- mation of the eyelids spreads further, and begins to affect the sclerotic conjunctiva, the effusion of tears ceases the eye becomes preternaturnlly dry, and the patient con- stantly thinks that he feels sand under the eyelids, which sensation is rendered almost intolerable by any motion of the eye, or eyelids. Children and women have so great a dread of this painful feel, that much per- suasion is often requisite to induce them to Jet the eye be properly examined. If the glandular inflammation of the eyelids attain a considerable degree, the lachrymal papilla; shrink, and the puncta seem closed, winch is particularly the case when the disorder begins at the inner canthus. In the second stage of the complaint, Beer describes the itching, burning sensation, and dryness of the eye, as undergoing a remark- able diminution, as either the canthi, or the whole extent of (he edges of the eyelids, become more and more moist, and smeared with mucus, an increased secretion of a pu - riform sebaceous fluid from the Meibomian glands being the first symptom, denoting the commencement of the second stage of the in- flammation. As this mucous secretion is not mixed with an adequate quantity of tears, it inspissates in the form of while, thin delicate layers, which, from time to time, cover the cornea, and make the patient very apprehensive of becoming blind, as the flame of a candle in the evening, and other objects appear to him more or less conceal- ed by a dense mist When, under these circumstances, however, the eyelids are repeatedly and briskly moved, or the eye is wiped, these appearances soon go off, the flakes of mucus being removed from the cornea. These accumulations of thickened mucus, Beer remarks, are apt to be most frequent and troublesome some time after a meal ; and the eyelids become so firmly glued to ether during sleep with yellowish crusts, that, when the patient awakes in the morning, it is not till after a great deal of washing and bathing of his eyes with warm water, that he is able to open them again. The above described change in the quantity and quality of the secreted matter, as al- ready mentioned, indicates th e first period of the second stage ; for Beer wishes it to be particularly noticed, that here, as in all in- flammations of mucous membranes, the se- cond stage of the disorder has three periods, as will be presently seen, to which the prac- titioner cannot be too attentive. This morbid secretion of a mucous seba- ceous matter does not continue long unat- tended with other efiects ; and, very soon, the peculiar appearances of suppuration are seen, at the same time that the conjunctiva of the eyelids becomes more considerably swelled, and a discharge takes place not only from the cantiii or margins of the eye- lids, but from the whole of the thickened villous surface of the palpebral conjuuctiva, and which discharge is distinguishable at first view from the mucus, which, at an ear- lier period, accumulated in much smaller quantity only between the edges of the eye- lids, and at the canthi. It is now no longer white, but ye!low r , completely like pus, with which it is in reality blended, and so viscid is it, that the crusts which collect on the eyelids in the nighttime cannot be removed, without pulling the eyelashes away with them. Sometimes, says Beer, at the moment of suppuration, minute pustules, which are scarcely distinguishable, form either at the canthi, or along the edges of the eyelids, and are sooti burst by the constant friction of the parts. These pustules indicate the second, or suppurative period of the second UPHTHALMY. 315 s * age ot the case, when either merely the canthus, or the whole of the margin of the eyelid, constantly becomes excoriated, and secretes mucus and purulent matter, the sore fretted places smarting so severely on exposure to the airy particularly to such as contains a large proportion of carbonic acid gasjind nitrogen, that the patient is afraid of opening his eye. When the patient neg- lects himself, and continues in an unhealthy atmosphere, these excoriations of the skin, occurring in the suppurative stage, are al- ways more extensive ; nay, they sometimes spread over the lower eyelid, and down the cheek At length, after the excoriations have lasted, perhaps, several weeks, the suppura- tive process is checked and suppressed, ei- ther by surgical treatment, or accidental fa- vourable circumstances, as change of regi- men, the weather, climate, &lc., and then the excoriations immediately diminish. However, a morbid secretion from the Mei- bomian glands still continues, making the third period of the second stage, and is apt to become habitual, if not rectified by art, or removed by the effect of accidental favour- able circumstances, when it changes into a thin serous discharge, and then terminates. Beer refers the causes of glandular inflam- mation of the eyelids , or simple purulent oph- tha'.my , to the immediate operation of va- rious stimuli acting chymically upon the edge of the eyelid, where it is covered with a very delicate cuticle, and upofi the ex- posed follicles of t e glands of the eyelid towards the inner canthus. Hence, says he, when many men are living together in a polluted, noxious air, impregnated with ex- traneous substances, this form of inflamma- tion is found to occur even in the strongest constitutions with such frequency, that it seems as if it were epidemic. And, accor- ding to Beer, the principal cause of the dis- ease will be found to be in the atmosphere, and the next most frequent occasion of it, be observes, is uncleanliness, as washing the eyes with foul water, &.<■. At the same time, this experienced oculist seems aware that this explanation would not of itself be always quite satisfactory ; for, he adds, that although, under the above circumstances, no constitution, no sex, nor age, is spared, there must be some particular condition which is conducive to the disorder, or at all events, to its more rapid and severe course, and the quick extension of the inflamma- tion in certain individuals, which condition Beer supposes must depend either upon weakness of constitution, or upon excessive irritability, or as he terms it, vulnerability of the whole surface of the body. Beer makes •no mention of the effect of damp nocturnal air in warm countries in giving origin to pu- rulent ophtbalmy. so much insisted upon by Assalini and Dr. Vetch, but, which doctrine, in reference to the origin of purulent oph- thalmies in England, I think completely fails ; and what is still more worthy of no- tice, Beer never attempts to explain the propagation of the disease by its infectious nature. It is observed by Dr. Vetch, that the history of all diseases, originating from some particular impression received from the atmosphere, but capable, when formed, of propagating themselves by contagion, is rendered particularly difficult; because the same circumstances, which favour the com- munication by contagion, produce also a predisposition to be acted upon by the more general causes existing in the atmosphere. The principal cause which gives force and opportunity to the action of contagion, is the crowding individuals together into too limited spaces. The same circumstance Dr. Vetch has seen give a predisposition to dis- eases of an epidemic, but not a contagious nature ; and hence he infers, that it may produce the same predisposition to diseases which are both contagious and atmospheric. “ The appearance of ophthalmia among the crews of ships and in barracks 'was often met with long before the late destructive and virulent disease (presently to be des- cribed.) In the army, such an ophthalmia has extended to whole regiments, without any appearance of the disease among the inhabitants of the neighbourhood ; and while the free intercourse which subsists among the men. as to washing in the same water, u-ing the same towels, and sleeping more than one in a bed, readily accounts for the rapid extension of the disease in the same corps, yet the excessive crowding to- gether of men will often of itself engender inflammation of the conjunctiva.” {Fetch on Diseases of the Eyes. p. 171.) I be- lieve with respect to the causes of all pu- rulent ophthahnies, our present knowledge will permit us to venture no further than the tenor of the preceding observations, which is, that they originate epidemically, but probably multiply both in this manner, and by the infectious matter of the disease being inadvertent ly applied in various ways to the eyelids of other persons. This spe- cies of inflammation of the eyelids is rarely met with by the surgeon in its first stage, because only very timorous patients then seek medical advice, and most individuals, who feel in other respects well, relieve themselves by washing the eyes with cold water, and applying cold poultices, made of bread crum softened in water. Besides, when the disease is not very severe, it fre- quently subsides of itself, as in a favourable constitution, a better air is sometimes capa- ble of restoring the healthy state of the eye. If, however, the disease at its very com- mencement should be violent, or attack an individual of very w T eak habit, Beer states that it may immediately affect, not only the Meibomian glands, but the perichondrium of the cartilage of the eyelid, and produce an incurable entropium, which is also sure of taking place when the case is neglected, and followed by deeply extending ulcerative mischief. When the complaint is strictly idiopathic, it never brings on any general indisposition, except by improper treatment it should happen to be converted into a violent inflammation of the whole eyelid, OPHTHALMic . 816 or what Beer terms a complete blcpharoph- Ihalmitis ; which he says, only happens in •weak subjects, and women and children, whose skin is in a very irritable state, or when a person of apparently good consti- tution remains under the influence of cir- cumstances which tend to augment the in- flammation, as for instance, exposed to the air of a stable, privy, foe. in which event. Beer describes the inflammation of the eye- lids as being quite of a peculiar description. As for the prognosis in the second stage, Beer observes, that, if the excoriations at the suppurative period should spread all over the edges of the eyelids, and compel the patient to keep his eye incessantly shut, a partial adhesion of the eyelids to each other ( ancliyloblepharon ) may be the result. Also, when at either of the periods of the secretion of mucus, or at that of suppura lion, the patient is content with merely sof- tening with warm water the thick matter glueing the eyelids together, so as just to be able to open his eye ; and does not com- pletely free the eyelashes from the crusts, clusters of the hairs will project inwards, (see Trichiasis ) whereby a secondary in- flammation of the conjunctiva of the eye- ball will be excited, which, Beer says, should be carefully discriminated from a mere extension of the glandular inflamma- tion of the eyelid. Such a trichiasis, he observes, may easily become incurable, when the edge of the eyelid is seriously in- jured by the depth of the excoriations. But, if the suppurative process be restricted chiefly to the canthus, especially the outer one (which case, according to Beer, is not unfrequent in old, debiliated subjects, of a relaxed constitution) and if the excoriations should deeply penetrate the commissure of the eyelids this may be completely destroy- ed, and the lower eyelid everted. As the state of the atmosphere, unclean- liness, crowded and close places, &c. are considered by Beer to be the principal causes of the glandular inflammation of the eye- lids, or simple purulent ophthalmy, one of the most important indications, in the first stage of the disorder, seems to him to be the removal of these hurtful circumstances. And, he declares, that, if immediate atten- tion be not paid to such indication, it will be quite impossible to prevent a dangerous increase of the disorder. A cool fresh air, and bathing the eye with cold water, or a weak lotion of vinegar arid water, Beer represents to be means, usually adequate to stille this inflammation in its birth. In the second stage, he says, the indication is entirely different. But, also in the beginning of this stage, and even at its second period, namely that of suppuration taking place, the disorder, according lo Beer, seems for a short time to be benefited by the employment of cold water, but the consequences are rendered by such treatment a great deal worse ; for a fresh, much more extensive inflammation of the same kind again takes place. At the first period of the second stage, viz. while the secretion is a pure mucous au& sebaceous matter, Beer says, that it is abso lutely necessary to employ such external means, as are calculated to promote the ac- tion of the veins and absorbents. For this purpose, he recommends the following col- lyrium : ]j^. Aq. rosa3 Z\v. Hydrarg. oxymur. gr. j. vcl.gr. dimidium. Mucil. sem cydori. 3j- Tinct opii vinos. Qj- Misce. This eyewater is to be used lukewarm from four to six times a day, and the eye afterward care- fully and completely dried. JSo eye, in this state, he says, will bear more than the pro- portion of one gr. of the oxymuriate of quicksilver, and only seldom more than half a grain. But, as soon as the suppurative period commences, attended with excoriations, gentle astringents, like the liquor plumbi subacetatis, in a solution of the lapis divinus (See Lachrymal Organs) should bt added to the above lotion, for which they may at length be entirely substituted. And, when the suppurative period has terminated, but a morbid secretion of mucus yet obstinately continues, and threatens to become habitual, recourse should be bad, without the least de- lay, to one of the following eyesalves, a bit of which, about the size of a small pea, Beer directs to be smeared once a day over the edges of the eyelids. Butyr. recen - tis insulsi ^ss. Hydrargyri nitrico-oxydi gr. x. Tutia? ptt. gr. vj. Misce. This oint- ment, he says, will sometimes answer ; but, that it is mostly necessary to use Janin’s salve, composed as follows: f^. Butyri re- centis insulsi ^ss. Hydrargyri praecipitati albi. gr. xv. Boli albi 3j. Misce. According to Mr. Travers, the mild acute suppurative inflammation of the conjunctiva is not attended w ith that excessive swell- ing of the eyelids, that intense pain, nor that profuse secretion, w ith which the vehe- ment acute form of the disease is character- ized. In the treatment, he directs a solution of alum to be early substituted for emollient fomentations, which he recommends to be freely used during the acute period. Simple purging and abstinence, he says, are gene- rally sufficient to allay the febrile irritation, which is moderate. Topical bleedings, and blisters, kept open on the back of the neck, are also stated to be of great efficacy. “ When the pain and irritability to light subside, and the discharge becomes gleety, the conjunctiva pale and flaccid, tonics, es- pecially the extract of bark and the acids, do gri:at good.” ( Synopsis , fyc. p. 264.) Catarrhal uphlkalmy, so called by Beer, is described by him as a species of glandular inflammation of the eyelids, attended with a simultaneous atfection of the mucous mem- brane of the nose, trachea, foe. brought on by particular states of the weather, and at- tacking so many persons at once, as to ap- pear epidemic. The prognosis and indica- tions are the same as those in common glau dular inflammation of the eyelids, with this exception, that attention must be paid lo the affection of other organs, and both at. the first and second periods of the second dPHT'HALMV. Si r Stage, such remedies given as operate power- fully on the mucous membranes and skin, and, in general, during the second stage, an equal warm temperature, and gentle diapho- retics, with camphor, are highly beneficial. Severe Purulent Ophlhalmy. — The Blepha- ro-blenorrhcea , and Ophthnlmo-blenorrhcea , of Schmidt and Beer; including the ophthalmia neonatorum; the Egyptian ophlhalmy ; the gonorrhoeal ophlhalmy, fyc., on w hich varie- ties, however, 1 shall annex to this account some further particulars, as they relate to each of these cases individually, because, though the following history contains an ex- cellent general description of the severe forms of suppurative inflammation of the conjunctiva, it leaves unexplained some of the circumstances on which its varieties de- pend. The vehement acute suppurative inflam- mation of the conjunctiva is described by Mr. Travers as being sudden in its attack ; a feature, in which it particularly differs from the milder cases usually met with in schools. (See Lloyd on Scrofula, p. 321.) It is accom- panied with most severe darting pains ; and the upper eyelid is sometimes in a few hours prolonged upon the cheek, owing to the in- filtration and enormous swellingof the tissue, connecting the conjunctiva to the tarsus. ( Travers , Synopsis, c %-c. p. 265.) According to Beer, the modification of glandular inflammation of the eyelids, here to be considered, consists entirely in the ra- pid extension of the inflammation and sup- puration, the disorder affecting, ere it is sus- pected, not only the whole of the conjuncti- va of the eyelid, but also that of the eye- ball, and the sclerotica and cornea. The swelling of the palpebral conjunctiva is de- scribed by Beer as being unusually great ; at first, soft, somewhat elastic, smooth, and readily bleeding; but, afterward, in the se- cond stage, hard and granulated, or, as ano- ther writer says, it “ becomes pi eternaturally vascular, thickened, and scabrous, or forms fleshy eminences.” ( Travers , Synopsis, fyc p. 96.) The first stage is rapidly over. At the first period of the second stage, the se- cretion both of mucus and pus is surprisingly copious. First, the mucus is whitish and thin ; but, as soon as the suppurative pro- cess begins, it becomes yellowish and thick, and when an attempt is made to open the eyelids, it gushes out with such force, and in so large a quantity, as frequently to cover, in an instant, the whole cheek. Sometimes, this mixture of mucus and matter contains light-coloured streaks of blood ; but, in worse cases, these streaks are dark and brownish, or else a thin ichor is discharged, in which case, the progress of the disease is so rapid, that the eye can seldom be sa- ved. The swelling of the conjunctiva of the eyelids, especially of that of the upper one, always increases during the first period of suppuration, and, when the discharge is more ichorous, the membrane is more gran- ulated, so that if the eyelid be opened care- lessly, or during the child’s crying, fits of pain. &c. the whole tumefied conjunctiva of the upper eyelid is immediately thrown outward, in the form of ectropium, and it is sometimes difficult, and even impracticable to turn the part inward again, especially, when the conjunctiva is already changed into a hard sarcomatous substance. While the swelling at the inner surface of the eye- lids continues to increase, their outer sur- face, particularly that of, the upper one, becomes reddened ; but the redness is dark- coloured, inclining to brown, and when the child cries, to blue. In children, the w hole cheek on the affected s : de is very often swelled, and sometimes the mucous mem- brane of the lachrymal sac and even of the nose, participates in the effects of the dis- order. Sometimes, at first, only one eye is affected, and the other is afterward attack- ed And, according to Beer, just before the period of suppuration, it is by no means un common for rather a profuse bleeding to to take place from the eye ; an event, which thou h it seriously alarm the parents of the child, or an adult patient, is hailed by the experienced surgeon as a favourable omen ; for, in such cases, the suppuration is generally very mild, and not of a destruc five kind, and the swelling of the « onjunc- tiva of the eyelids, as well as that of the sclerotic^ conjunctiva, if already present, soon undergoes a remarkable diminution after such hemorrhage, which often recurs two or three times. When during the first, very short ami transient stage, the inflam mation extends also to the sclerotic con- junctiva, this membrane forms a pale-red, soft, irregular swelling, all round the cor- nea, which at length seems so buried, that at the period of the mucous secretion, its centre can hardly be discerned ; and, when suppuration begins, both rnucus and pus are discharged from the conjunctiva of the eyeball in profust' quantity, particularly ac- cumulating over the cornea, and not unfre- quently drying into a thick pellicle, when long detained in the eye. Hence, the case looks as if the whole eyeball, or at least, all the cornea, were in a state of complete sup- puration. At length, the tumefied conjunc- tiva of the eyeball becomes sarcomatous, though never in such a degree as that of the eyelids. hen the suppurative period cea- ses, and with it the most urgent danger to the eye, the secretion of mucus alone con- tinues, as at the first period of the second stage, the swelling of the conjunctiva of the eyelids, and of the sclerotic conjuncti- va, when this has also been affected, dimi- nishes, and the disorder ends in an increased effusion of tears or true epiphora. When the effects of the suppuration upon the con- junctiva of the eyeball are more severe, the corneal production of this membrane in the most favourable cases is raised from the sub- jacent cornea, and so opaque, that the eye- sight is lost, or at all events seriously impair- ed, until the transparency returns, which is sometimes late, especially when efficient treatment is not put in practice. Should the suppuration be very deep, the cornea, which always turns whiter and whiter, pre- QPHTH ALMV, 318 sents near the edge of the swelling of the conjunctiva an arrangement, similar to that of the leaves of an old book, and at length seems converted into a mass of purulent matter, which projects more and more out of the depression in the swelled conjunc- tiva, and then bursts in its centre either quickly and with very violent pain, or slow- ly without any suffering, an oval hole being left, behind which the yet transparent crys ta 1 line lens appears, included in its undama- ged capsule. At this period, adults can often see very plainly, and fancy their recovery near at hand, or, at least, all danger over. Already, however, every part of the cornea has been more or less perforated by ulcera- tion, the iris protrudes through all these apertures, so as to form what has sometimes been named the staphyloma racemosum. In a very short time, not exceeding a few hours, the capsule of the lens is affected, and bursts like the cornea, when it is dis- charged either with, or without, a portion of the vitreous humour. At length, the suppuration subsides, and with it the pro- trusions of the iris, the opening in the cornea becoming closed with a brown, or bluish, opaque fiat cicatrix But, if in this destruc- tive form of suppuration, nothing is done for the relief of the disease, the whole eye- ball suppurates, theeyelids become concave instead of convex, and the fissure between them closes for ever. In adults of feeble constitutions, when the case is not properly treated, but particularly in weak children, this excessively violent form of conjuncti- val inflammation and suppuration spreads with such rapidity, that a considerable ge- neral disturbance of the system is occasion- ed. Indeed, according to Mr. Travers, in the common course of this vehement form of conjunctiva! suppurative ophthalmy, the system sympathizes ; chilliness is succeeded by a hot and dry skin ; and the pulse is frequent and hard. Yet, it is particularly pointed out by the army surgeons, that one peculiarity of the Egyptian purulent oph- thalmy is its being generally attended with little constitutional disturbance. When the above-described annihilation of the eyeball takes place, it always creates violent gene- ral indisposition in unhealthy weak chil- dren, and even leaves adults for along while afterward in an impaired state of health. According 1o Beer, who appears to have no idea of infection being concerned the particular cause ot this unfortunate exten- sion of idiopathic glandular inflammation of the eyelids, both in infants and adults, frequently depends altogether upon the foul atmosphere, in which they are residing, and hence, says he, the disorder is, as it were, endemic in lying-in and foundling hospitals, where the air is much contaminated by ef- fluvia, from the lochia, the crowding toge- ther of many uncleanly persons, dirty clouts, &,c The unjustifiable folly of exposing the eyes of new-born infants to every degree of light ; a tedious labour, in which the child’s head is detained a long while in the vagina ; and roughly washing the eyes after birth with a coarse sponge; are other cir- cumstances, supposed by Beer to be condu- cive to the origin of the complaint, in new- born infants. The reality of many of these causes I regard myself with a great deal of doubt ; and nsfor hisconjecture, thatsprink- liug cold water on the head in baptism, while in a state of perspiration, may pro- duce the complaint, it is too absurd to need any serious refutation. The disorder, he says, is always more rapid and perilous in new-born infants than adults; ( B . 1, p. 318,) a remark which does not agree with the statements usually made, if the Egyp- tian ophthalmy, as seen in the army, be comprehended. It is observed by Mr. Travers, that the highly contagious nature of the suppurative ophthalmia, whether in the mild, or vehement acute form, is suffi- ciently proved. For one person, affected with this disease above three months old, he thinks at least twenty are attacked under that age. “ The mother is the subject of fluoralbus, or gonorrhoea, and the discharge is usually perceived about the third day.’’ ( Synopsis , fyc. p. 97.) Some further obser- vations on the causes of some of these severe modifications of glandular inflammation of the eyelids will be introduced, after the prognosis and treatment have been consi- dered. This will be the more necessary, as the propagation of the disorder by infection is here entirely overlooked. According to Beer, whenever an idiopa- thic inflammation of the glands of the eye- lids attains the severe forms, exhibited in the purulent ophthalmy of infants, the Egyp- tian ophthalmy, and gonorrhoeal ophthalmy, the prognosis must naturally be unfavoura- ble, and this in a greater degree, the more the inflammation and suppuration have ex- tended to the eyeball itself. The cases are still more unpromising, when they happen in poor, half-starved, distressed individuals, whom it is impossible completely to extri- cate from the circumstances, which either cause, or have a pernicious effect upon the disease. Should an incidental ectropiurn not be immediately rectified, says Beer, it will continue until the end of the second stage, and even frequently longer, so as to require particular treatment. When at the period of suppuration, merely the layer of the conjunctiva, spread over the cornea, is destroyed, the prognosis, in respect to the complete recovery of the eyesight, is fa- vourable, although it takes place but slow- ly. If the effects of the disease at this period should be deeper, yet the cornea not destroyed, only rendered flat and somewhat opaque ; or, if the cornea should be ulcerated only at a very lim- ited point; there will remain in the first case, an opacity of the cornea ; but, in the second, a partial adhesion of the iris to the latter membrane (synechia anterior) is apt to follow, with a more or less extensive ci- catrix on the cornea, covering in a greater or lesser degree the lessened and displaced pupil, and thus diminishing, or preventing vision. When, during the inflammation OPHTHALMY. 819 aud suppuration, a considerable part, or the whole of the iris adheres to the cornea, and this is not penetrated by ulceration, the re- sult, in the first case, is a partial , in the se- cond, a complete staphyloma of the cornea, which does not fully develope itself, until towards the decline of the second stage of the ophthalruo-blennorrhcea. If the inflam- mation should spread to the tejitures of the eyeball itself, so as to produce severe con Stitutional disturbance, the eye wastes away in the midst of the profuse discharge, the eyelids sink inwards, and the fissure between them becomes permanently closed. (Beer, B. 1, p. 319.) Beer notices the opinion of the celebrated Schmidt, which was, that the opthalmo- hlennorrhcea, orpurulent ophthalmy involv- ing the sclerotic conjunctiva, always has a fixed duration of a mouth, in new-born in- fants, and of six, eight, or twelve weeks, in very weak individuals. Beer acknowledges the correctness of this opiuion, only in cases where the surgeon has to deal with a completely formed ophthalmo-blennorrhoea, and not in a more recent case, or one in which the disease is chiefiy confined to the inside of the eyelids. ( Blepharo-blennor - rhoea.) When the disorder is met with in the first period of the second stage, or it is confined to the palpebral conjunctiva and Meibomian glands, and truly idiopathic, Beer asserts, that its course may be restrict- ed by efficient treatment to a few days, as he has often proved in the establishment for foundlings at Vienna. It is further remarked by Beer, that, in this modification of genuine idiopathic glan- dular inflammation of the eyelids, the in- dications have something peculiar in them. If, by chance, the surgeon meet with the disease in its first stage, it will be most bene- fited by the application of folded linen wet with cold water ; and sometimes a brisk purge of jalap and calomel, and putting a leech over the lachrymal sac at the inner canthus, will promote the subsidence of this dangerous species of ophthalmy. The case, however, jrarely presents itself for me- dical treatment thus early, and, in hospitals, Beer says, antiphlogistic treatment is, on this account , hardly ever indicated. With some exceptions of importance, the treatment, advised by Beer, for the second stage of these severer forms of purulent ophthalmy, resembles that proposed by him for the second stage of simple glandular in- flammation of the eyelids, or the milder varieties. These more severe kinds of puru- lent inflammation of the eye, implied by blepharo-blennorrhcea and ophthalmo-blen- norrhoea, he says, should never be viewed and treated merely as local disorders ; but that, both in children and adults, internal remedies should be exhibited, particularly volatile tonic medicines. In cases, where the cornea is already attacked by a destruc- tive ulcerative process, manifold experience has convinced him, that bark, combined with naphtha, and the tincture of opium, is the only means of saving the eye : but, that if the suppuration be confined to the eye- lids, the decoction of calamus aromati- cus with naphtha and opium will mostly answ r er. When, on the supervention of suppuration, the pain in the eye and neigh- bouring parts is excessively severe, Beer assures us, that friction with a liniment of opium will give great relief. In new-born infants, the maternal milk of right quality will mostly do more good, than internal medicines : but if the case be very urgent, and the child feeble, Beer thinks volatile medicines may sometimes do good. With respect to particularities made ne- cessary in the local treatment by the modified nature of the inflammation. Beer otters the following information. First, in new-born infants, or very young children, the oxymu- muriate of mercury cannot be used without danger, though blunted with mucilage; and even in adults, it should be employed in these cases with great circumspection. Se- condly, the mucus and purulent matter should not be allowed to remain long under the eyelids, as such lodgment is found to promote the destruction of the layer of the conjunctiva situated on the cornea; but, at the same time, Beer thinks, that leaving any water on the eyes, after cleaning them, and letting it become cold there, will have quite as pernicious an effect. Hence, he is very particular in directing all the mucus and purulent matter to be wiped away from the eye with a bit of fine sponge moistened with a warm mucilaginous collyrium, but not so w et as to let the fluid drop out of it ; or when they are very copious, and in large flakes, he even recommends them to be washed away by means of Anel’s syringe ; but. he says, that every part about the eye should be immediately afterward well dried with a warm napkin, and then covered with a w arm camphorated compress. Thir-ily , during the suppurative period, according to Beer, com- mon tincture of opium, or the vinous tincture is the best local application, the parts being smeared with it twice a day, by means of a fine camel-hair brush. It is only in a few instances, that a small proportion of the lapsis divinus (see Lachrymal Organs ,) mixed with the mucilaginous collyrium, can be endured. Beer declares, that he has never seen any good produced by Bates’s campho- rated lotion, w hich was so highly praised by the late Mr. Ware. Fourthly, when the suppurative period has terminated, the mu- cous secretion again becomes vvliite and thin, as at the very commencement of the second stage, but it is always more copious ; now 7 is the time, (as in the last stage of simple glandular inflammation of the eyelids) when the topical use of mercury, joined w 7 ith styptics, especially in the form of an eye- salve, is indicated. Fifthly, if an eversion of the upper eyelid should happen from washing the eye carelessly, or the mere crying of the infant, in consequence of the thickened granulated state of the palpebral conjunctiva, the position of the eyelid must, if possible, be immediately rectified ; for afterward, this cannot be done. In order to OPHTHALMY. mo avoid this ectropium, the eyelids should irritation are past, and the cornea retains ite never be opened while the child is crying, or tone and brightness, Mr. Travers considers in any way agitated; for, at such periods, the the case safe, and states, that the prompt thickened scabrous conjunctiva will sudden exhibition of tonics, with the use of cooling ly protrude, and cannot be kept buck. Beer astringent lotions, will prevent its lapsing says, that the eyelid should be replaced in into a chronic form. “ But if, when the the manner directed by Schmidt. ( Ophthal - lowering practice has been pushed to the mo/ Bibl. 3. R. 2. Stuck, p. 149.) The surgeon extent of arresting acute inflammation, the having smeared the e^ds of the thumb and patient being at the same time sunk and ex- forefinger of each of his hands with fresh hausted. the cornea shows a lack lustre and butter, is to take hold of the everted raggedness of its whole surface, as if shrunk cartilage of the eyelid at the outer and by immersion in an acid, or a gray patch in innercanthus, draw it slowly a little upwards, the centre, or a line encircling, or half en- and then suddenly downw ards. Thus, the circling its base, assuming a similar appear- fhickened conjunctiva, if not too fleshy and ance, the portion so marked out will infalli- granulated, may be quickly reduced, and bly be deta* bed by a rapid slough, unless by the ectropium removed. But, if the swelling a successful rally of the patient’s powers, we ot this membrane should he already very can set up the adhesive inflammation, so as considerable, and have begun to be hard and to preserve in situ that which may remain studded with excrescences, tiiethumbs should transparent.” (Synopsis, fyc. p. 266.) Here be placed so as to compress rather the we find some approximation of practice, be- middle of the eyelid. However, if the ectro- tween Mr. Travers and Professor Beer ; but piura cannot be at once removed, it is to be it is almost the only point, in which any re- treated, after the termination of the second semblance can be found in their modes of stage of the purulent opbthalrny, as a sequel treatment. of this disorder. (See Ectropium .) The granulated, or fungous state of the In the ophthal mo-blennorrhcea the altera- palpebral conjunctiva, produced by puru- tion of the sclerotic conjunctiva is said by lent ophthalmy, sometimes demands parti- Beer to be very different from chemosis ; a cular treatment, after the original disease is vemark, which is strictly correct, inasmuch subdued. If such state of the eyelid be not as ordinary chemosis is not attended with rectified, it often keeps up a “ gleety dis- til at change in the surface of the sclerotic charge, irritability to light, drooping of the conjunctiva, which fits it for the secretion upper lid, a pricking sensation as of sand in of pus. But, if we are to understand by the eye, and a preternaturally irritable and chemosis, a copious effusion of lymph in the vascular state of the sclerotic conjunctiva j loose cellular substance between the con- with these are frequently combined opaci- junctiva and the eyeball, this state must be ties of the cornea.” (Travers, op. cit. p. 271.) admitted as one of the usual effects of severe The affection, as conjoined with opaque purulent ophthalmy. cornea, is particularly noticed by Dr. Vetch, “ It is after this morbid condition, which who describes the disease of the palpebrae as is characteristic of the suppurative ophthal- consisting, at first, in a highly villous state of mia (says Mr. Travers) that the conjunctiva their membranous lining, which, if not forms fungous excrescences, pendulous treated by appropriate remedies, gives birth flaps, or hard callous rolls protruding be- to granulations, which in process of time tween the palpebraS and globe, and everting become more deeply sulcated, hard, or the former, or, if not protruding, causing the warty. Along with the villous and fleshy turning of the lid over against the globe, appearance of the lining of the eyelids, there The tarsal portion takes on from the same is a general oozing of purulent matter, which cause the hard granulated surface, which may at any time be squeezed out by press- keeps up incessant irritation of the sclerotic ing the finger on the part. The diseased conjunctiva, and at length renders the cornea structure is highly vascular, and bleeds most opaque.” (Synopsis, Q-c.' p. 9 8.) profusely when cut. It possesses, as all The treatment recommended by Mr. Tra- granulated surfaces do, a very great power ' vers for the vehement acute suppurative of growth or reproduction. Dr. Vetch has inflammation of the conjunctiva consists in seen many cases in which it has been remo- a very copious venesection, by which, be ved with more zeal than discretion, twenty says, the pain is mitigated, if not removed ; or thirty times successively, without this the pulse softened ; and the patient sinks disposition to reproduction having suffered into a sound sleep and perspires freely. The any diminution. Indeed, he assures us, that high scarlet hue and bulk of the chemosis the operation was very unfavourable to the are sensibly reduced, and the cornea is ultimate recovery of the part ; “ a new sur- brighter. The blood-letting, if necessary, is face is produced of a bright velvety appear- to be repeated, and the patient briskly ance, much less susceptible of cure than the purged, every dose of the opening medicine original disease, and which, even if at length being followed by a lea-spoonful of a solu- healed, does not assume the natural appear- tion of emetic tartar, so as to keep up a ance of the part, but that of a cicatrized stale of nausea, perspiration, and faintness, surface,” not attended with a return of the When the discharge becomes thin, gleety, transparency of the cornea. It is s&tisfacto- and more abundant, the swelling of the eye- l ily proved, by the observations of Dr. lid subsides, the conjunctiva sinks and be- Vetch, that this diseased state of the inner pale and fiebbv. the pain and febrile surface of the eyelid was not. only known to ©PHTHAUVTY. .321 ilhases, and other old practitioners, under the names of sycosis, trachoma, scabies pal- pebrarum, &c. but that its treatment by the actual cautery, excision, and friction, was also recommended by them. The honour of having introduced the preferable mode of cure with escharotics, Dr. Vetch assigns to St. Ives. No substances appear to Dr. Vetch more effectual for this purpose than the sulphate of copper and nitrate of silver. He says, that they should be pointed in the form of a pencil, and fixed in a port-crayon. They are to be applied, not as some have conceived, with the view of producing a slough over the whole surface, but with great delicacy, and in so many points only, as will produce a gradual change in the condition and disposition of the part. As long as any purulency remains, Dr. Vetch states, that the above applications will be much aided by the daily use of the liquor plumbi subacetatis. When the disease re- sists these remedies, and the surface is hard and warty, he applies very minute quanti- ties of finely levigated powder of verdigris, or burnt alum, to the everted surface, with a fine camel-hair pencil, but carefully Washes them off with a syringe before the eyelid is returned. The caustic potassa, lightly applied to the more prominent parts of the diseased surface, will also answer. (See Vetch on Disease's of the F.ye p. 73, is seldom the slightist alteration of the pulse, unless the lancet hare been freely employed. The patient’s general health is little impaired, his appetite conti- nues natural, but sleep almost totally for- sakes him. As the pain abates, the external tumefac- tion also subsides, and a gaping appearance of the eyelids succeeds, their edges, instead of being inverted, now becoming everted. This is what Dr Vetch designates as the third stage of the disease. After the swelling of the second stage has subsided, the eyelids are prevented from returning to their natural s ate by the gra- nulated change of the conjunctiva which lines them ; and an eversion of them now occurs in a greater or lesser degree ( Vetch on Diseases of the Eye , p. 196, 2< 2 ) Among other interesting remarks, made by the same author, he states, that there is no reason to warrant the idea that the ulceration ever proceeds from within outwards. He ob- serves, that, when any large portion of the cornea sloughs, an adventitious and vascu- lar membrane is often produced, which finally forms a staphyloma. “In some few cases, (says he) 1 have seen the lens and its capsule exposed, without any external co- vering whatever, and, for a short time, the patient saw every thing with wonderful ac- curacy; but, as soon as the capsule gives way, the lens, and more or less of the vitre- ous humour, escape, the eye shrinks, and the cornea contracts into a small horn-co- loured speck.” This total destruction of the globe of the eye is said generally to en- sure the other, and renders it less liable to be affected by future attacks of inflamma- tion. A few years ago, an ophthalmy, supposed to be of the same nature as the Egyptian, though milder, like that which has generally been observed in schools, occurred to a great extent in the Royal Military Asylum at Chelsea, and Mr. M ‘Gregor, the surgeon of that institution^ has favoured the public with an excellent description of the disease, and some highly interesting facts and reflec- tions upon the subject. In the Military Asylum the symptoms of this species of ophthalmy generally made their appearance in the following order: “A considerable degree of itching was first felt in the even- ing; this was succeeded by a sticking toge- ther of the eyelids, principally complained (>f by the patient on waking in the morning, ’(the eyelids appeared fuller externally than they naturally are ; and on examining their internal surface this was found inflamed. The sebaceous glands of the tarsi were con- siderably enlarged, and of a redder colour than usual. The caruncula lachrymalis had a similar appearance. “ In 24 or 30 hours after the appearance of the above-mentioned symptoms, a viscid mucous discharge took place from the inter- nal surface of each eyelid, and lodged at the inner canthus, till the quantity was sufficient to be pressed over the cheek by the motions of the eye. The vessels of the tunica con- junctiva, covering the eyeball, were distend- ed with red blood, and the tunica conjunc- tiva was generally so thickened, and raised, as to form an elevated border round the transparent cornea. This state was often accompanied with redness of the skin round the eye, which sometimes extended to a con- siderable distance, and resembled, in colour and form, very much what takes place in the cow-pox pustule, between the 9th and 12th days after inoculation. “ When the purulent discharge was con- siderable, there was a swelling of the ex- ternal eyelids, which often prevented the patient from opening them for several days. The discharge also frequently excoriated the cheeks as it trickled down Exposure to light caused pain When light was excluded, and the eye kept from motion, pain was sel- dom much complained of “These symptoms, in many, subsided, without much aid from medicine, in 10 , 12, or 14 days, leaving the eye for a considera- ble time in an irritable state. In several, however, the disease continued for a much longer time, and ulceration took place oa the internal surface of the eyelids, and in different parts on the eyeball. If one of those small ulcers happened to be situated on the transparent cornea, it generally, on healing, left a white speck, which, however, in the young subjects under our care, was commonly soon removed. In some few instances, an abscess took place in the sub- stance of the eyeball, which, bursting ex- ternally, produced irrecoverable blindness.” (P Gregor, in Trans, of a Socirty for the Improvement of Med. and Chirwg. Knowledge, Tot. 3, p. 3»— 40.) Whet! the local symptoms had prevailed two or three days, some febrile disturbance occurred ; but, except in severe cases, it was scarcely observable. Mr M ‘Gregor considered this ophthalmy to be of the same nature as that which has raged with such violence in the army at dif- ferent periods, since the return of our troop' from Egypt in 1800, 1801, and 1802. How- ever, he has found that its consequences have not been so injurious to children as to adults; for, out of the great number of children that were afflicted with the disease at the Military Asylum, only six lost the sight of both eyes, and twelve the sight ops lately in the latter coun- try, who at one time were threatened w ith a very extensive renewal of the Egyptian nph- thalmy among Item, but which was w isely checked by attention to the principles above specified, and in which Dr. Grant, the head of tiie medical department of that army, had the greatest confidence. In the cases under Mr. M‘Gregor, local applications were found most advantageous. Dating the inflammatory stage, however, this gentleman also had recourse to antiphlo- gistic means, spare diet, bleeding, neutral salts, &,c. The topical treatment was as fol- lows: Leeches were freely and repeatedly applied near the eye. But while there was much surrounding redness, instead of leeches, which created too much irritation, fomenta- tions, with n weak decoction of poppy-heads, and a little brandy, were used. A weak so- lution of acetate of lead, and sulphate of zinc, had mostly a good effect when applied to the eye. The vinous tincture of opium did not answer the expectations entertained of it. But of all the remedies, the ung. hy- drarg. nitrat.was found most frequently suc- cessful. It W'as applied by means of a camel- hair pencil and at first weakened with twice its quantity of lard. The red precipitate, well levigated, and mixed with simple oint- ment, sometimes answered when the ung. hydrarg. nit rat . failed. Well levigated verdi- gris, and a quack medicine, called the golden ointment, proved also sometimes efficacious. ( P . 41 — 43.) According to Mr. M‘ Gregor, blisters behind the ears, and upon the neck, ore useful ; but hurtful when put nearer to the eye. In cases wdiere the disease seems to resist antiphlogistic means, and ulceration has commenced on the external surface of the cornea, thi- gentleman approve; of dis- charging t he aqueous humour by a puncture, os advised by Mr. Wardrop. When the violence of the inflammation has subsided, Mr. M Gregor recommend- the us** of Bates’s camphorated water, diluted with four, five, or six times its quantity of wafer. But the astringent collyrium, from which he saw most good derived, was a so lution of the nitrate of silver, in the propor- tion of half a grain to every ounce of dis- tilled water. In some cases, it may be used stronger. Tepid sea-w-ater sometimes proved ser- viceable in removing the relics of the com- plaint. ( P . 56 tye.) The late Mr. Ware was in favour of bleed- ing ; but he rardy carried it to the ex:ent which has been done in the army. In weak persons, instead of repealed venesection, he preferred topical bleeding, either from the vein that passes on the side of the nose, or by means of five or six leeches put on the temple. Sometimes he thought it better to scarify the inside of the lower eyelid with the point of a lancet, carried along parallel to, and very near the margin of this part He objects to pricking the eyelid in an infi- nite number of places, as very painful, and likely to increase the irritation. The lancet (he says) never need be applied more than twice, and rarely more than once ; and, per- haps, less pain w ill be occasioned by making the incision with the edge, rather than the point of the lancet. After taking away blood, Mr. Ware says, a large blister on the h**ad, or back, is often useful. Anodynes should be given, with occasional purgatives, and an antiphlogistic regimen. {Ware on Purulent Ophthalmy , ISOS p. 26, <^c-) As a local application, Mr. Ware preferred tiie aqua camphorata, which was used exact- ly in the same way, as will be described i« speaking of his method of treating the puru- lent ophthalmy of children. When the in- flammation was very great, he only put four or five grains, instead of eight, of the sul- phate of copper to eight ounces of water. He usually employed the lotion cold, espe- cially in children; but in adults, in whom the general fever and local inflammation were considerable, he was obliged to use it warm. In cases of great pain and swelling, it should be very weak, less often applied, and sometimes only warm water injected. In such circumstances, Mr. Ware also sanc- tions fomenting the eye with a flannel, or sponge, wet with a hot decoction of poppy - li&nds, or mere hot water. When i he cor- nea threatens to burst, this gentleman ap- proves of opening it, in order to discharge the aqueous humour, by making an incision in a place where the scar will not obstruct vision, as first suggested by Mr. Wardrop. Purulent Ophthalmy oj Infants. Dr. Vetch describes the external appearances of this case as not materially different from those of the purulent ophthalmy of adults; but, he states, that its nature is considerably modi- fied by the more delicate texture and great- er vasculari'y of the parts affected, and the more intimate connexion, subsisting between the vessels of the conjunctiva and those of the scleiotic coat. Hence, he says, the in- flammation is sooner communicated to this coal, and sloughing and ulceration of the cornea occur earlier in infants, than adults. When the oedema ceases, the inner surface of the palpebrse becomes sarcomatous, and this diseased surface, when the eyelids are opened; forms an exterior fleshy circle, be- yond which the relaxed conjunctiva of the eye comes forward as a second ; and often the caruncula lachrymalis adds still farther to the valvular appearancp, which the pmrt pre- sents. (On Diseases of the Eye , p. 256— 258 .) According to the late Mr. Ware, the prin- cipal difference between the purulent oph- th almy in infants and that in adults, consists i'll the different states of the tunica conjuncti- va: in the former, notwithstanding the quan- tity of matter confined within the eyelids is often profuse, the inflammation of the con- junctiva is rarely considerable, and when- ever the cornea become? impaired, it is rather 328 OPHT owing to the lodgment of such matter on it than to inflammation ; a statement, which appears to me very questionable. But, in the purulent ophthalmy of adults, the dis- charge is always accompanied with a violent inflammation, and generally wilh a tumefac- tion of the conjunctiva, by which its mem- branous appearance is destroyed, and the cornea is nntde to seem sunk in the eyeball. ( Ware on Epidemic Purulent Ophthalmy , p. 123.) In children, the alfection of the eyes is occasionally accompanied with eruptions on the head, and with marks of a scrofu- lous constitution. (See Ware , p. 138, fyc.) The only inference to be drawn from this fact is, that scrofulous, as well as other chil- dren, are liable to this disorder of their eyes. The following is the treatment recommend- ed by Mr. Ware. If the disease be in its first stage, the temporal arteries are to be opened, or leeches applied to the temples, or neighbourhood of the eyelids, and a Mis ter put on the nape of the neck and temples. The child should be kept in a cool room, not covered with much clothes, and if no diarrhcea prevail, a little rhubarb or mag- nesia in syrup of violets should be prescribed. A surgeon, however, is seldom called in before the first short inflammatory stage has ceased, and an immense discharge of matter from the eyes has commenced Of course, (says Mr. Ware,) emollient applications must generally not be used. On the contrary, as- tringents and corroborants are immediately indicated, in order to restore to the vessels of the conjunctiva and eyelids their original tone, to rectify the villous and fungous ap- pearance of the lining of the palpebrae, and thus finally to check the morbid secretion of matter. For this purpose Mr. Ware strongly recommends the aqua camphorata of Bates’s Dispensa ory : Capri sulphatis, bol. ar- rnen. a a |iv. Camphorae, Jj. M. &f. pulvis, de quo projice ^j. in aqua? bullientis amove ab igne, ef subsidant foeces. Mr. Ware, in his late Remarks on Purulent Oph- thalmy, 1803, observes, that he usually directs the aqua camphorata as follows: Cupri sulphatis. bol. armen. a & gr viij. Camphorae gr ij. Misce, et affunde aqua? bullientis ?viij. CCtm lotio sit frigida, effundatur limpidus li- quor, et saepissirne injiciatur paululum inter oculum et palpebras. This remedy possesses a very styptic quality ; but, as directed in Bates’s Dispensatory, it is much too strong for use before it is diluted; and the degree of its dilution must always be determined by the peculiar circumstance of each case. Mr. Ware ventures to recommend about one dram of it to be mixed with an ounce of cold clear water, as a medium or standard, to be strengthened or weakened ns occasion may require. (P. 143.) The remedy must be ap- plied by means of a small ivory or pewter syringe* the end of which is a blunt-pointed cone. The extremity of this instrument is to be placed between the edges of the eye- lids, in such a manner, that the m» dicated li- quor may be carried over the whole surface of the eye. Thus the. matter will be entirely washed aw ay, and enough of the styptic me- dicine left behind to interrocf and diminish HAT Ml. the excessive discharge. According to the quantity of matter, and the rapidity with which it is secreted, the strength of the ap- plication, and the frequency of repeating it, must he regulated. In mild recent cases, the lotion may be u-ed once or twice a day. and rather weaker than the above proportions ; but, in inveterate cases, it is necessary to ap- ply it once or twice every hour, and to in- crease its styptic power in proportion ; and when the complaint is somewhat relieved, the strength of the lotion may bo, lessened, and its application be less frequent. “The reasons for a frequent repetilion of the means just mentioned, in bad cases, are. indeed, of the most urgent nature. Until the conjunctiva is somewhat thinned, and the quantity of the discharge diminished, it is impossible to know in what state the eye is ; whether it is more or less injured, totally lost, or capable of any relief. The continu- ance or extinction of the sight frequently de- pends on the space ot a few r hours : nor can we be relieved from the greatest uncertainty in these respects, until the cornea becomes visible.” (Ware- p. 145.) This author condemns the use of emollient poultices, which must have a tendency to in- crease the swelling and relaxation of the con- junctiva. If poultices are preferred, he par- ticularly recommends such as possess a tonic or mild astringent property; as one made of the curds of milk, turned with alum, and an equal part of the unguentum 9ambuci, or axungia porcini. This is to be put on cold, and frequently renewed, without omitting ,he use of the injection. (Ware, p. 147.) When the secreted matter is glutinous, and makes the eyelids so adherent together, that they cannot be opened, after being shut for any length of lime, the adhesive matter must be softened with a little fresh butter mixed with warm milk, or by means of any othersoft oleaginous liquor, after the poultice is taken off, and before using the lotion. (P.. 147.) If the eversion of the eyelids only occurs when the child cries, and then goes off, no- thing need be done in addition to the above means. When, however, the eversion is con- stant, the injection must be repeated more, frequently than in other cases; the eyelids put in their natural position, after its use ; and an attendant directed to hold on them, with his finger, for some length of- time, a compress dipped in the diluted aqua camplio rata. (P. 148.) In some cases, when the inside of the eye- lids has been very much inflamed, the tine- tura thebaica, insinuated between the eye and the eyelids, has been useful. If, after the morbid secretion i3 checked, nny part of the cornea should be opaque, the unguert- tum bydrargyri nitrati, melted in n spoon, and applied accurately on the speck, with u fine hair pencil ; or Janin’s ophthalmic, oint- ment, lowered and used in the same mariner, may produce a cure, if the opacity' he not of too deep a kind. When the local disease seems to be kept up by a bad habit, altera- tives should be exhibited, particularly tiPH'VH ALM \ . 32l> black sulpburet of mercury, or small dosesof eyes, was freely applied to (be orifice of (he calomel. urethra. No effect followed (his trial, which The treatment, recommended by Dr. was repeated on some other, patients, all la- Vetch, is as follows: if the inflammation has bouring under the most virulent state of the not extended to the conjunctiva of the eye, Egyptian disease, and in all the application its further progress may he checked by re- was perfectly innocuous. But, in another moving the infant to a healthy atmosphere, case, where the matter was taken from the and washing the eye with any mild collyri- eye of one man, labouring under purulent, um. Leeches are commended throughout ophthalmia, and applied to the urethra of ari- the whole course of the complaint. On the other, the purulent inflammation of the nre first accession of the tumefaction, t he best thra commenced in thirty-six hours after- effect will- often be produced by the applica- ward, and became a very severe attack of tion of a small portion of ointment, composed gonorrhoea. From the result of these cases, of lard, or butter 3yj. and x gr. of the red ni- (says Dr. Vetch) l could no longer admit the trate of mercury, without any wax. As the possibility of infection being conveyed to purulency advances, the liquor plumbi suba- the eyes from (he gonorrhoeal discharge of (he cetatis, he says, will be found not less ser- same person. Some time after this, the im viceahle, than in other instances of purulent probability, or rather impossibility of this ef- ophthalmy. For promoting the separation feet, was rendered decisive by an hospital of any slough, he recommends a solution of assi-tant, who conveyed the matter of gonor- the nitrate of silver: and for curing the re- rhcea to his eyes, without any affection of the laxed state of the conjunctiva, a solution of conjunctiva being the consequence.” (See alum, or of the sulphate of copper. (On Vetch on Diseases of the Eye , p. 242.) Diseases of the Eye , p. 260.) Hence, this gentleman is led to refer the con The Purulent Ophthalmy arising either nexion, between gonorrhoea and ophthalmia, from suppression of gonorrhoea, or from the in the same person, to peculiarity of consti- ihadvertent conveyance of gonorrhoeal matter tutiou; but the theories on which this opi to the eyes, is said to produce rather 1 a swell- nion rests, my limits will not allow me to ing of the conjunctiva, than of the eyelids, examine which is followed by a discharge of a yei- If it be actually true, that, in adults, a spe • low greenish matter, similar to that of clap, cies of purulent ophthalmy does originate The heat and pain in the eyes are con- from the sudden suppression of a gonorrhoea, siderable ; an aversion to light prevails, and, are we to consider the complaint so pro- in some instances, an appearance of hypopi- ducedas a metastasis of the disease from the on is visible in the anterior chamber oi the urethra to the eyes ? This ophthalmy does aqueous humour. When the complaint pro- not regularly follow the suppression of gonor- eeeds from the secondcause.it is described rhcea; nay, it is even a rare occurrence: as being less severe, than when it arises from also, when it is decidedly known, that the the first. However, by such gentlemen, purulent ophthalmy has arisen from the in- ( Ware , Travers, fyc.) as have seen unequivo- faction of gonorrhoea, namely, in those in cal instances of purulent ophthalmy excited stances in which the matter has been incau- in the second way, the disease is said to be tiously communicated to the eyes, it appears remarkable for its violence and intensity, that such an affection of these organs, so pro- The reality of cases of purulent ophthalmy duced, is different from the one alluded to, from the application of gonorrhoeal matter to inasmuch as it is slower in its progress, and the eyes, seems supported by such a mass of less threatening in its aspect. When the evidence, that I believe the fact must be ad- eyes are affected, the disease of the urethra mitted. Yet, from some statements, lately is not always suspended. (Vetch on Diseases published b\ Dr. Vetch, it would appear, that of the Eye. p. 239.) Hence, there is good the frequency of this mode of infection must reason for supposing that no metastasis takes be very much lessened by the circumstance place in (his species of purulent ophthalmy, of the matter taken from the urethra, not supposed to be connected with a suppressed being capable of communicating the dis- gonorrhoea: but, we must be content with ease to the eyes of the individual, by whom inferring that, if it really has such a cause, it such matter is secreted, though probably originates from a sympathy, prevailing be- capable of doing so to the eyes of another tween the urethra and eyes, and, that the person. difference of irritability, in different people, In the same way, the urethra caunot be is the reason, why it is not an invariable affected by the application of matter taken consequence of the sudden stoppage of a from the purulent eyes of the individual, on gonorrhoea. Whom the experiment is made. At least, of The injection of warm oil, the introduc these circumstances, there is a negative proof tion of a bougie into the urethra, and the in some facts recorded by Dr. Vetch. “ In application of cataplasms to the perinaeum, the case of a soldier, received in a very ad- with a view of renewing the discharge from vanced stage of the Egyptian ophthalmia, in the urethra, form the outline of the practice whom destruction of the cornea had to a cer of those who place implicit reliance in the tain extent taken place, I took occasion to suppression of gonorrhoea being the cause represent the possibility of diverting the dis- of the complaint. The rarity of the occur- ca«e from the eyes to the urethra, by apply- rence; the frequency of the sudden cessa- ing the discharge 1o the latter surface. Ac- tion of the urethral discharge ; the possibi- cordingly, some of the matter taken from the lity of an ophthalmy arising, as well at this V 0L . II. 42 OPHTIIALMF particular moment, as at any other, totally independent of the other complaint ; cannot fail lo raise in a discerning mind a degree of doubt concerning the veracity of the assign- ed cause. Besides, admitting that there is a sympathy between the urethra and eyes, how are we to ascertain whetherthe suppres- sion of gonorrhoea be the cause or the effect of the ophthalmy, supposing that the one ceases and the other commences about the same time ? Actuated by such reflections, I am induced to dissuade surgeons from adopt ing any means calculated to renew a dis- charge of matter from the urethra. When the purulent ophthalmy, in adult subjects, is decidedly occasioned by the actual contact, and infection of gonorrhoeal matter, applied accidentally to the eyes, no one has recom- mended this unnecessary and improper prac- tice. The first indication in the treatment of the disease from either cause, is to oppose the violence of the inflammation, and thus re- sist the destruction of the eye and opacity of the cornea. A copious quantity of blood should be taken away both topically and ge- nerally ; mild laxatives should be exhibited, and a blister applied to the nape of the neck, or temples. The eyes ought to be often fo- mented with a decoction of white poppy- heads, and warm milk repeatedly injected beneath the eyelids. To prevent the palpe- brse from becoming agglutinated together, during sleep, the spermaceti cerate should be smeared on the margins of the tarsi every night. When the heat and pain in the eyes, and febrile symptoms have subsided ; when an abundant discharge of pus has commenced; all topical emollients are to be relinquished, and a collyrium of Aq. rosse |x. containing Ilydrarg. oxy. mur. gr. j. used in their place. Scarpa slates, that in the ophthalmia, origi- nating from the inadvertent communication of the matter of gonorrhoea to the eyes, ap- plications, in the form of ointment, such as the ung. hydrarg. and Janin’s salve, to which might be added the ung. hyd. nitrat. avail more, than fluid remedies. Inflammation of the Eyeball in general. From cases in which the eyelids are at first chiefly affected, I pass to the consideration of inflammation, as commencing in the eye- ball itself. As Beer remarks, fortunately it is only very seldom, that the whole ol the organ is at once attacked with genuine idio- pathic inflammation, without any part of its texture being spared. Although this kind of ophthalmy is far more frequent than com- mon inflammation of the orbit, it is much more rare than the same disorder of the eye- lids. For the most part, healthy inflamma- tion of the eyeball has a limited point of ori- gin, from which it spreads, sometimes quick- ly, sometimes slowly over the whole organ. During an exceedingly violent, tense, throb- bing pain, affecting not only the eye itself, but extending to all the surrounding parts, the bottom of the orbit, and within the head, the white of the eye becomes suffused with an uniform redness, which, on attentive ex- amination, is found to be seated not only in the conjunctiva of the eyeball, but also in the sclerotica, and to exhibit at first a very fine vascular network, which, as the redness grows more intense, assumes the appearance of scarlet cloth, forming all round the cor- nea an uniform circular prominent fold, which has a very firm feel, and is so tender, that, when touched in the gentlest manner, the patient cries out with agony. The cir- cumference of the cornea continues to be more and more covered by this increasing swelling of the conjunctiva, until at length only a portion of its centre remains visible. At the same time, the pupil is very much contracted ; the iris motionless ; and though vision is nearly or entirely lost, the patient is seriously disturbed by fiery appearances before the eye. When the iris is naturally gray, or blue, it turns greenish, and when brown, or black, it becomes reddish. Every movement of the eyeball and upper eyelid is suspended, and the orbit feels to the pa- tient, as if it were too small, which, Beer says, is in reality the case, because the whole of the eyeball, and not merely the conjunctiva, is enlarged, so as to project like a lump of raw flesh further and further between the edges of the palpebrae, and com- pletely fill every part of the orbit. While the eyeball enlarges, the cornea always loses its transparency, and the inflammation spreads to the eyelids, the lower one at last becoming everted by the excessive and firm tumefaction of the parts behind it, and the upper one presenting the most unequivocal marks of phlegmonous in- flammation. The secretion of tears and mucus is now entirely suppressed, and of course, the eye preternaturally dry. At the very commencement of this violent form of ophthalmy, the constitution is disturbed by a t-vere attack of inflam- matory fever, and irritable patients are not unfrequently seized with delirium. — Here, says Beer, terminates the first stage of this very dangerous disorder. When the disease is left to itself, suppura- tion comes on, attended with fever and constant shiverings ; the swelling of the scle- rotic conjunctiva undergoes a remarkable increase, and assumes a dark red colour, at the same time that it becomes softer. The pain becomes irregular, throbbing, and. when the eye or eyelids are touched, of a lancinating description. As a morbid secre- tion now begins to take place from the Mei- bomian glands, the swelled conjunctiva has a more moist appearance. The upper eyelid, has a purple hue, and, on account of the con- tinually increasing size of the eyeball, is pushed further and further outward. The portion of the cornea, still discernible in the middle of the protuberant conjunctiva, ac- quires a snowy whiteness, which afterward changes to yellow. The patient feels an op- pressive sense of heaviness in the orbit, and a disagreeable kind of coldness all round the eye. At length the throbbing and ten OPIITHALMV. 331 sion are so agonizing, that the patient often expresses a wish to have the eyeball extir- pated. If no effectual treatment be adopted, the eye now bursts, and a mixture of matter and blood, together with the scarcely per- ceptible remains of the lens and vitreous humour, is discharged with considerable force to some distance in front of the pa- tient ; an occurrence sometimes termed rhexis , or rhegma oculi. From this moment, the pain all at once subsides into a very mo- derate feel of burning in the eye ; and sup- puration goes on, until all the textures of the organ are annihilated, the orbit has an emp- ty appearance, and the closed eyelids sink into a concavity. Thus ends, as Beer ob- serves, the second stage, after much tedious and general indisposition. But, he remarks, that the course of the case is quite different, when it has been wrongly treated in its first stage with stimulants, or exposed to the ill effects of tobacco smoke, the drinking of spirits, improper diet, immoderate exercise, &.c.; for, under the operation of these unfa- vourable circumstances, the second stage may commence with dreadful gangrenous mischief, every vestige of the organization of the eye disappearing, and the parts at length sphacelating, while large abscesses form around, and, unless efficient medical aid be promptly given, the patient loses his life. With respect to the causes of such an at- tack of the whole eyeball at once by com- mon inflammation in a healthy subject, they must be of an exceedingly violent descrip- tion, such as injuries produced by gunpow- der, burns, and lesions either of a mechani- cal kind, or acting both chymically and me- chanically together, a subject already fully treated of in the foregoing columns. The following are the observations which Beer delivers on the prognosis : While, in the first stage of this dangerous form of oph- thalmy, the eyesight yet remains, and the eyeball itself is not enlarged, if the patient can be properly taken care of, some hope may be entertained of dispersing the inflam- mation so favourably, that, with the excep- tion of a weakness of sight, of longer or shorter continuance, no ill effects will be left. It is manifest, however, that under these circumstances, the surgeon should not be too bold in promising a perfect cure; for, the very commencement of such an inflam- mation of the whole eyeball, even when the disorder is purely idiopathic, is unavoidably attended with some risk, not only of perma- nent blindness, but of the eye itself being destroyed in the most painful manner; and, when things turn out rather better, a tolerably favourable termination of the case is uncommon. But, as soon as the power of seeing is quite lost, the pupil nearly closed, and the eyeball prodigiously swelled, it will be fortunate, if the inflammation can be resolved, so as to preserve the shape of the organ ; for the restoration of the eye- sight is entirely out of the question. But, besides the irremediable loss of vision, the disorder under these circumstances always produces a greater ®r lesser closure of the pupil, which, however, lias no share in caus- ing the blindness. In the second stage of the case, of course, the hope of restoring vision is quite past , and if the eyeball itself, and not merely the conjunctiva, has been considerably swelled in the first stage of the case, the chance of preserving the natural shape of the organ extremely unpromising. But, when the eye bursts, the latter desideratum is impossible. If the first stage should have been so violent as to have induced gangrene, the practition- er will have enough to do in preventing sphacelus, and death, the danger of which is considerable, on account of the intimate connexion between the eye and parts in the orbit, and the brain and its membranes. In the first stage, antiphlogistic treatment, in the general sense of the expression, is indicated, and the case is not to be re- garded merely as a local disorder. Howe- ver, with respect to topical bleedings, the surgeon, says Beer, should be more active, than in other examples of ophthalmy, and, after copious venesection and the use of leeches have produced some relief, the pro- tuberant conjunctiva, round the cornea, should be deeply scarified with a lancet. If, in the first stage, delirium come on, as it sometimes does during the violence of the inflammatory fever, Beer directs one of the external jugular veins to be opened: or blood might be taken from the temporal artery. In the second stage of the case, when the re-establishment of vision is quite im- impossible, and the objects are to endeavour to keep the eye of a good shape, and quick- ly lessen the suppuration, warm emollient poultices, and particularly those made of apples, are the applications, on which Beer bestows his praises. This topical treatment is to be assisted with internal means, as ex- plained in the preceding pages, because the disorder is attended with a general disturb- ance of the constitution. When matter is fully formed, and its fluctuation can be dis- tinctly felt, Beer approves of opening the abscess with a lancet; for, it is only by this means, that the annihilation of the eyeball can be prevented. If the eye has already burst, the preservation of its form is no lon- ger possible, and, according to Beer, both the topical and general treatment should be partly of a tonic description. When gan- grenous mischief has occurred, the practice ought to conform to the principles explain- ed in the article Mortification. External Ophthalmy. Inflammation of the Outer Coats of the Eye. Ophthalmitis Externa Idiopathica , of Beer. The modifications of this common species of ophthalmy, as the latter author observes, have a variety of names applied to them, as ophthalmia levis , ophthalmia angutaris, tar axis, and sotnetim* £ chemosis, and ophthalmia sicca. Together with a preternatural dryness of the eye, and a sensation, as if the eyeball were compress- ed on every side, the white of the eye be- jeoeaes covered with a general rednejs.Sj OPHTHALMV. 332 which, though it, affect both the sclerotica and the conjunctiva, will be found on attentive examination to be much more considerable in the former, than the latter membrane, in which only a delicate plexus of blood-ves sels is at first perceptible. The motions of the eye and eyelids are not absolutely prevent- ed ; yet, the patient never moves these parts except when he is actually obliged to do so, as every motion of them, if not actually painful, occasions a good deal of annoy- ance. Though the cornea cannot be said to become opaque, its clearness is always much diminished, and this change is the greater, the redder the white of the eye ap- pears. These effects, which occur almost simultaneously, are followed by pain, which increases every moment, at first extending over the whole eyeball, and then to the sur- rounding parts, and to the top of the head. As the pain grow s more severe, every move- ment of the eyeball and palpebraj becomes more distressing, the dryness of the eye greater, and the redness of the sclerotic conjunctiva augments, either more slowly, or quickly, according to the degree of in- flammation until the network of blood-ves- sels, which was at first distinguishable, en- tirely disappears, and the conjunctiva looks like a piece of red cloth, quite concealing the sclerotica, and forming round the cor- nea a very painful, firm, uniform circular projection. Thus, the cornea seems as if it lay in a depression, with its margin partly covered by this inflammatory swelling of the conjunctiva. At the period, when the protuberance of the latter membrane takes place, the cornea itself always becomes less and less clear, and of a reddish gray colour, so that neither the iris nor the pupil can be any longer distinguished, and the power of vision is reduced to a faint perception of light. The pain, which was that of heavi- ness and tension, now becomes of a throb- bing description, and the eyelids, which now begin to participate in the effects of the inflammation, are no longer capable of covering properly the swelled conjunctiva. The eyeball and eyelids are perfectly mo- tionless ; and, if an attempt be made by the patient to move them, the efforts of the muscles may be perceived, but still no movement of the parts intended is perform- ed. The orbit feels as if it were too small for the eye, and the constitution suffers a severe attack of inflammatory fever. Thus, says Beer, does the first stage of this form of ophthalmv gradually rise to its highest degree, to which he applies the name of true chemosis. However, it is observed, that idiopathic external ophthalmy does not always be- come so violent, as for instance, when the complaint has been excited merely by the lodgment of some small foreign body under tbe eyelids ; for though in such a case the conjunctiva and sclerotica are both redden- ed together, yet even when no aid is afford- ed, if no other sources of greater irritation are present, the redness does not readily increase so as quite to conceal the sclero- tica, or to be attended with an inflamma- tory swelling all around the cornea. This milder form of external ophthalmy has sometimes received the name oi tar axis. It is the mild acute ophthalmy of Scarpa, cha- racterized, as this author says, by redness of the conjunctiva and lining of the eyelids, an unnatural sensation of heat in the eyes, uneasiness, itching, and shooting pains, as if sand w ere lodged between the eye and eye- lids. At the place where the pain seems most severe, Scarpa remarks, that some blood-vessels appear more prominent and turgid than other vessels of the same class. The patient keeps his eyelids closed ; for he feels a weariness and restraint in opening them, and by this means be also moderates the action of the light, to which he cannot expose himself, without increasing the burn- ing sensation, lancinating pain, and effusion of tears. If the constitution be irritable, the pulse w ill be a little accelerated, parti- cularly towards the evening ; the skin dry ; and sometimes slight shiverings, and nausea and sickness take place. According to Scarpa, mild acute ophthal- my is often the consequence of a cold, in which the eyes, as well as the pituitary ca- vities, fauces, and trachea, are affected. It is not unfrequently occasioned by change of weather, sudden transitions from heat to cold, the prevalence of easterly winds, jour- neys through damp unhealthy, sandy coun- tries, in the hot season of the year, exposure of the eyes to the vivid rays of the sun., draughts of cold air, dust, &c. Hence, it does not seem extraordinary, that it should often make its appearance as an epidemic, and afflict persons of every age and sex. As additions to the list of remote causes, authors enumerate the suppression of some habitual evacuation, as bleedings from the nose, or piles, the menses, he. a disordered state of the prima* viae, worms, dentition, &c. Between Beer and some late w riters, there is either one point of difference in their de- scriptions of external ophthalmy, or else they mean different cases ; for while Beer represents the redness as affecting the scle- rotica at first more than the conjunctiva, other writers describe the affection of t he scle- rotica as generally secondary, when it hap- pens at all ; for according to modern obser- vations, it is not unavoidably either an at- tendant upon, or an effect of simple inflam- mation of the conjunctiva. As the second stage of external ophthal- my comes on, the symptoms vary, accord- ing to the degree of the complaint in its first stage ; but when what Beer calls a true chemosis is produced, the following are de- scribed by him as llie usual appearances. The circular prominent fold of the conjunc- tiva round the cornea, becomes of a dark red colour, and the swelling increases, but it becomes softer and less painful. The hardly visible portion of the cornea, situated iu the depression formed by the circular protuberance of the conjunctiva, seems at first perfectly white, and afterward yellow- ish, being the seat of more or less purulent matter. Though the swelled conjunctiva is every where moistened with a thin whi- tish mucus, this secretion, says Beer, is never so copious as to run over the face, as in the case of ophthalmo-blennorrhcea. In this stage, the lower eyelid is turned some- what outwards, in consequence of its lining becoming more swelled. While suppura- tion is taking place in the cornea, attended with the febrile symptoms which usually ac- company the formation of acute abscesses, little collections of matter sometimes occur at different points of the conjunctiva, and after they have burst, a probe may easily be passed rather deeply into them, without any particular pain. (Beer, B. 1,/). 412.) The suppuration continually advancing, the swellingof the conjunctiva, and of the whole eyeball now diminishes, the effects of the inflammation penetrate deeply into the or- gan, and the structure of the eye is so alter- ed as not to be cognizable, the part shrivel- ling up, as Beer says, into a motionless, whitish mass. However, according to this author, these deep effects of suppuration are sometimes produced only in a certain part of the eyeball, especially when the chemosis is the consequence of an external injury, and in this circumstance, the rest of the circumference of the globe of the eye exhibits its natural organization, while in the part above alluded to, there is a funnel- like depression, attended with a considera- ble diminution in the size of the organ. But, says Beer, when an idiopathic exter- nal inflammation of the eye has only attain- ed the milder degree, expressed by the term taraxis ; as, for instance, when the com- plaint is principally owing to the lodgment of some mechanically, or chyriucally irrita- ting substance under the eyelids . the red- ness of the conjunctiva and sclerotica un- dergoes a remarkable increase on the ac- cession of the second stage ; the first of these membranes becomes somewhat swell- ed ; the pain is lancinating and irregular ; and the secretion of tears unusually pro- fuse ; but at the point where the extraneous substance lodges, an open superficial sup- puration occurs, and according to Beer, the case both in the first and second stage, is generally accompanied with no febrile symptoms. In the first stage, Beer represents the prognosis as very favourable, provided the disorder does not exceed that degree, to which the name of iaraxis is applied; for with the aid of proper treatment, the in- flarnmaiion. when of a healthy kind, may be soon so favourably removed, as not to leave a vestige of it behind. If the cause of the disorder be not greater than a moderate injury or wound of the eve, any traces of the lesion, which are perhaps still remain- ing, will disappear as soon as the inflamma- tion subsides. On the other hand, when this kind of ophthalmy presents itself in the form of true chemosis, the prognosis is serious, and must be made with great re- serve, especially when the patient is of a weak irritable constitution, a child, very- stubborn and unmanageable, or incapable of following strictly the advice which he receives froth his medical attendant ; for, under these circumstances, it will not be in the power of the latter to prevent the com- plaint from advancing unremittingly to its second stage, in which event the ill conse- quences of suppuration w ill be incalculable. But if these unfavourable conditions are not present, though the genuine idiopathic che- inosis may really have attained a violent, and almost its highest degree in the first stage, not only the eye may be saved by prompt and judicious treatment, but als© the eyesight ; nor will the result be differ- ent, even when the cornea continues for some time deprived of its transparency, and the power of vision impaired by a slight varicose affection of its conjunctival cover- ing. These effects, says Beer at length completely disappear, less in consequence of the aid of medicine, than of a proper regimen, the uninterrupted enjoyment of a fresh, dry air, &c. The prognosis in the second stage, is un- der very different circumstances ; for, a^ Beer observes, though the inflammation, in the first stage may really not exceed that degree which is implied by the term iaraxis, yet if any suppurating point, occasioned by some slight preceding injury, be not effi- ciently treated, or if there be any loss of substance, already produced by the injury itself, a more or less opaque, white cicatrix is apt to remain on the cornea, and cause a permanent impediment to vision in a degree determined by the situation and extent of the opacity. And in addition to this risk it is to be remembered, that if the suppurating point be entirely neglected, or erroneously treated, the cornea or sclerotica may be penetrated by ulceration, and in the first case, a prolapsus of the iris, an adhesion of this organ to the cornea, (synechia anterior,) a disfigurement of the pupil, or an irregu- larity of the cornea, be produced ; while, in the second, the consequences may be a partial wasting away of the eyeball, attend- ed with loss of sight, and of the natural shape of the part. (Beer. B. 1, p. 417.) Beer further observes, that when this species of ophihalmy presents itself in its first stage in the form of true chemosis, the prognosis in the second stage is very unfa- vourable ; for when the cornea is generally pervaded by suppuration, the eyesight, and, in some degree, the form of the eyeball, are for ever lost, and it will be lucky, if the case can be brought to a conclusion with the mere destruction of the cornea. Br?t when the matter points at once in several places of (he conjunctiva, round the cornea, all idea of preserving (he shape of the eye sufficiently for the application of an artifi- cial eye is out of the question, and the sur- geon will be very successful, if he can now check in moderate time the suppuration, which continues with a good deal of gene- ral indisposition. An extraordinary relaxa- tion of the con junctiva of the lower eyelid, OPHTHALMY. 334 and a consequent ectropium, are the least disastrous effects of the abscesses of the eye thus produced. Lastly, Beer remarks, that when chemosis is in the second stage, that is to say, attended with suppuration of the eye, it rarely happens, under the most fa- vourable circumstances, that the eyesight and shape of the organ can be preserved entirely free from permanent injury. ( B . 1, j V • 418.) Let us next consider the treatment of idio- pathic external ophthaliny in its modifica- tions of simple inflammation of the con- junctiva, mild acute ophthalray, or taraxis, and severe acute opi.thalmy, with che- tnosis. According to Mr. Travers, simple inflam- mation of the conjunctiva unconnected with injury of tiie eye, and neither depend- ing upon any established disorder of the system, nor modified by a scrofulous dia- thesis, may be easily and speedily reduced, even in its most acute form, by bleeding and some brisk doses of purgative medicine. ( Synopsis of the Diseases of the Eye, p. 247.) For the relief of mild acute ophthaliny, Scarpa recommends low diet, gentle purging with small repeated doses of aritimonium tartarizatum, the removal of any extraneous body lodged under the eyelid, and frequently washing the eye with a warm decoction of mallow leaves, and covering it with a very soft emollient poultice, included in a fine little muslin bag. Mr Travers also expresses his decided preference to a tepid application in the painfully acute stage of inflammation, and considers simple warm water generally better than medicated lotions, like the aque- ous solution of opium, or infusions of poppy and hemlock. When the disease presents itself in its first stage, in the mild form of taraxis, says Beer, it usually runs its course, quite uncomplica- ted with any general indisposition, and may be cured by moderate antiphlogistic treat- ment, in which, indeed, since the eyeball it- self is affected, particular attention must be paid to lessening the action of the light and air upon the organ. But when a true che- mosis is present, every antiphlogistit means must be promptly and rigorously put in practice, internal as well as external reme- dies being employed, and besides common measures, the conjunctiva, round the cor nea, is to be scarified ; a proceeding never necessary in the case of taraxis. Such sca- rifications, Beer observes, have a wonderful effect when practised at the proper period, aft r veneseci ion and topical bleeding with leeches have been fully put in execution, and when the cuts are made deep, so as to produce immediately a copious discharge of blood. “ By means of such scarifica- tions (says he) I have seen the inflam- mation and all its threatening effects re- cede, as it were, before my face, when no material relief could be effected by other measures.” ( B . 1, p. 419.) According to the late Mr. Ware, there cannot be, in chemosis, an easier or more effectual remedy than set her. A few drops are to be poured Into the palm of the hand., and diffused over it, which may be imme- diately done by pressing the other hand against it The hand is then to be applied to the eye, and kept so close to it that the spirit, as it evaporates, may insinuate itself into the part affected, and act on the extra- vasated blood, so as to disperse it. In a few instances of chemosis, in which the swelling and inflammation have been considerable, this gentleman found the following applica- tion of singular service : f^. lnteriorum fo- liorum recentiurn Lactucae Sissilis ^iij. Coque cum aq. pur. 3-ss. in balneo mariao pro semihora ; tunc exprimatur succus, et applicetur paululum ad oculos et ad palpe- bras saepe indie. (Ware, p. 54) As these applications are not noticed by the genera- lity of modern writers, I infer, that the supe- rior efficacy imputed to them by the late Mr. Ware, is not such as to obtain the con- fidence of all other ophthalmic practitioners. General and local bleeding, and, if chemo- sis be present, scarifications having been put in practice, the treatment is to be continued by administering purgatives of the mildest description, and, after their operation, apply- ing blisters, according to the directions given in a preceding part of this article. Ia the first stage of severe acute ophthalmy, Scarpa considers topical emollient applica- tions to the eye most beneficial, such as mallows boiled in new milk; bread and milk poultices; or the soft pulp of a baked apple ; all included in fine little muslin bags. Remedies of this description should be re- newed at least every two hours. The pa- tient should be directed to observe perfect quietude, and to lie with his head in an elevated position. To keep the eyelids from adhering together in the night-time, the spermaceti cerate is proper. When ophthalmy is accompanied with a violent pain in the head, the late Mr. Ware recom- mended a strong decoction of poppy-heads to be applied as a fomentation. (P.51.) Under the preceding plan of treatment, the first stage of severe ophthalmy com- monly abates in about a week The burning heat and darting pains in the eyes, and the febrile disturbance of the constitution sub- side. The patient is comparatively easy, and regains his appetite. The eyes become moist again, and can now be opened without experiencing vast irritation from a moderate light. In this state, notwithstanding they may continue red, and the conjunctiva swelled, all evacuations are to be left off, as well as the use of topical emollients, for which iatter astringent, corroborant collyria are to be substituted. Scarpa recommends the following application : f^. Zinci sul- phatis gr vj. Aquae distillate ^vj. Mucil. sein. cydon. mali j. Spiritfis vini cam- phor guttas paucas. Misce et cola. This collyriutn maybe injected with a syringe, between the eye and eyelids, once every two hours; or the eye may be bathed in it by means of an eye-cup. Such persons as cannot bear cold applications to the eye, must have the same hind ef collyriutn a little OPHTHALMY ib& unarmed ; but as soon as the irritability is lessened, it may be used cold. Scarpa then speaks of the good effects produced in the second stage of ophthalmy by the application to the eye of two or three drops of the vinous tincture of opium, once or twice a day ; a subject already consider- ed in the foregoing columns. The utility of letting the eye be habituated to the light, as soon as it can bear it, is next strongly commended; a rule of great importance, but on which 1 need not here dwell, be- cause it has been already insisted upon in the general observations. When idiopathic external ophthalmy has terminated in suppurations of little extent, Beer speaks highly of the benefit derived from a solution of the lapis divinus, (see Lachrymal Organs) containing the liquor plumbi subacetatis, or from smearing the suppurating points with a little laudanum. In worse cases, Beer states, that, when such local treatment is combined with the inter- nal exhibition of bark and naphtha, and a diet and regimen conducive to the support of the system, its efficacy is very great. And here, says he, it is worth observing, that while the solution of the lapis divinis is of great service in the second stage of true chemosis, it is more or less detrimental in the kind of chemosis which accompanies purulent ophthalmy, especially if not blend- ed with mucilage, and, even w hen thus qua- lified, it cannot be endured by weak and irritable subjects, affected with the latter complaint ; a fact not observed in other in- stances of chemosis. (B. 1, p. 42u.) To Mr. Ware’s use of ajther in chemosis, 1 have already adverted. When pustules, or abscesses in the swell- ed conjunctiva point round the cornea, a free outlet to the matter must be immedi- ately made in each of them with a lancet; for, if this be not done, as Beer observes, the matter will spread extensively, and the eyeball be in danger of being destroyed. For an account of the method of treating the eversion of the lower eyelid, sometimes re- maining as a consequence of the disorder, see Eclropium. Inflammation of the Sclerotica. Sclerotitis. - — The modern attempts to class ophthal- mies, according to the texture of the eye first or chiefly affected promises, I think, to load to clearer views of the subject, and sounder practice. One circumstance, par- ticularly adverted to, both by Dr. Vetch and Mr. Travers, in inflammation of the sclero- tica, is the appearnuce of a vascular zone at the margin of the cornea. By the latter gentleman, this effect is ascribed to the par- ticular distribution of the vessel's. “Branches from the straight vessels of the conjunctiva, penetrate Ihe sclerotica obliquely towards the margin of the cornea, and the long ci- liary vessels pass in sulci of this membrane to the plexus ciliaris at the root of the iris. At the interior border of the sclerotica, where the annulus ciliaris is adhering closely to this tunic, the ciliary communicate with the : muscular branches, and being in deep- seated inflammation fully injected with red blood, the condensation of colour gives the well-known and remarkable appearance of a vascular zone at the margin of the cornea.” ( Synopsis , tyc. p. 126.) According to Dr. Vetch, only a few interspersed trunks are posteriorly observed, “which do not affect the natural appearance of the intermediate space, but these, diverging as they come forwards. produce a zone more or less com- plete, of minute hair-like vessels, distin- guished by their rectilinear direction, and their uniform concentration towards the margin of the cornea ; their colour advances w ith the progress of the disease, from that of a delicate pink, or damask rose, to a deeper hue, and imparting a faint blush to the part immediately surrounding it.” (On Diseases of the Eye. p 27.) There appears, however, to be a good deal of variety in the symptoms of sclerotitis ; for rheumatic in- flammation of the eye, described by Pro- fessor Beer and Mr. Ward rop, as particularly affecting the sclerotica in common with other fibrous membranes, is not noticed by these authors as characterized by the red zone round the edge of the cornea. Indeed, instead oi there being posteriorly only a few interspersed trunks, Mr. Wardrop states, “that (in rheumatic ophthalmy) the blood- vesseis are generallv. equally numerous over the whole white of the eye, passing forwards in nearly straight lines from the posterior part of the eyeball, and advancing close to the cornea ; but neither passing over it nor leaving the pale circle around it , which is so striking when either the choroid coat or iris is inflamed. If the vessels be closely exami- ned, the genera! redness will be found pro- duced more from numerous small ramifica- tions than a few large trunks.” (Med. Chir. Trans. Vol. 10, p. 3.) However, as if there must be no harmony on this subject, Beer describes the blood vessels, in rheumatic ophthalmy, not as being equally numerous over the whole white of the eye, but as be- ing in some places collected in larger numbers or clusters, and he differs again from Mr. Wardrop, in describing the redness as coming on with considerable intolerance of light, ( Lehre von den Angenkr. B. 1, p. 397 — 398,) while the latter :-uthor distinctly mentions, that “ the eye does not seem to suffer from exposure to lights” (Med. Chir. Trans. Vol. 10, p. 6.) I can only reconcile these accounts by concluding, that sclero- tic inflammation, like that of other textures of the eye, has stages and modifications which account for these seeming contradic- tions. And, with respect to the vascular zone round the edge of the cornea, it would appear, at all events, to belong to iritis, as well as sclerotic inflammation. The vessels of the sclerotic coat are observed by Dr. Vetch tu'follow the motion of the eye, and he says, that they may, by this circumstance, be distinguished from those of the conjunc- tiva, “ the vessels of the latter, independent of their darker colour, their more tortuous form, and varying size, have likewise a more longitudinal direction, and as they proceed 336 OPHiHALMV from the angles ot the orbit, they form radii of a larger circle. The distinction between the inflamed vessels of the conjunctiva and the sclerotica, (says Dr. Vetch) I consider to be, therefore, obvious ; but, that any dif- ference can be observed in the arrangement - or appearance of the vessels of the I, alter, suffi- ciently distinct to indicate the peculiarity of the exciting came , or specific nature of the case, is more than l have been uole to perceive. The general character, as it arises out of the structure of the part, will be found the same, whether the cause be gout, rheumatism, or syphilis. The vessels, such as l have de- scribed them, will always be most observa- ble on the upper portion of the eye, as it is in that place that the inflammation is most intense, except when its locality is affected by any external exciting cause, in which case it will be greatest near the injured part.” {On Diseases of the Eye, p. 29.) While Dr. Vetch describes the vessels of the conjunctiva as exhibiting in sclerotic inflammation a darker colour than that of the vessels of the sclerotic coat itself, Mr. Tra- vers represents the vessels of the latter mem- brane, which pursue a straight course to the margin of the cornea, as having a somewhat darker hue than the areolar vessels upon the loose portion of the conjunctiva. It should be mentioned, however, that by sclerotic inflammation. Dr. Vetch signi- fies inflammation of the eye itself, as con- trasted with conjunctival inflammation ; but, how far this will account for the differ- ences, above pointed out, between his des- cription and that of Mr. Travers, 1 am not prepared to say. According to Mr. Travers, ordinary inflammation of the sclerotica is secondary, that is to say, this membrane is usually affected only as intermediate to the conjunctiva and the other tunics. How- ever, he has occasionally observed, in a re- cent ophthalmia, a turgescence of the ves- sels, which pur&ue a straight course to the cornea, unaccompanied with any affection of the iris, and so slight a vascularity of the loose conjunctiva, that he was disposed to regard the case as a primary sclerotitis. The inflammation he says, is not acute, and the motions of the eyeball are painful. It sometimes accompanies, and sometimes fol- lows rheumatic inflammation. If continued, it presents the vascular zone and a pupil contracted, or drawn a little to one side. It is often seen in company with eruptions, or sorethroat, of a pseudo-syphilitic cha- racter, oris secondary to gonorrhoea. ( Tra- vers , Synopsis, tyc.p. 123.) The practice, recommended by this gen- tleman, is as follows : obtuse pain in the eyeball, he says, may he materially relieved by blood-letting, and by antimony and ipeca- cuanha with opiates. Mercury is stated to have much less power over this case, than iritis. In general, the patient is seriously reduced, and very irritable, from suffering, rheumatic inflammation in the elbow, knee, or ankle; a state, to the produc ion of which the previous use of mercury has com- monly contributed but though such is stated to be the case, the moderate ana cau- tious employment of this mineral is set down as generally indispensable in the treatment And in the interval of the mercurial action, the nitric acid is alleged often to be of great service. The preparations of mercury pre- ferred by Mr. Travers in these cases, are the oxymuriate in doses of one 1-12 or 1-8 of a grain, and the hydrargyrus cuin crela, in doses of from five to ten grains, twice or thrice a day. As auxiliaries for allaying ir- ritation, he prescribes the pulv. ipecac, comp, hemlock, hyosciamus, and the extract of sar- saparilla; either dissolved in the decoction, or taker* solid. (Vol. cit.p. 289.) On rheumatic inflammation of the eye, a few observations will be hereafter inserted. Idiopathic Inflammation of the Internal Tex- tures of the Eyeball, or Internal Ophthalmy in general. According to Beer, internal in - flammation of the eye does not always ori ginate in one particular texture, but, in some instances, commences in the retina, choroi des, &.c. ; while, on other occasions, its prin - cipal seat is in the iris, from which mem- brane it quickly extends itself to the corpus ciliare, and the crystalline lens and its cap- sule. or else in another direction to the scle- rotica, cornea, &.c. These differences in the seat of the disorder obviously depend upon the way in which the exciting causes have operated ; for, when they are such as imme- diately affect the retina only, the inflamma- tion must have Us origin in this texture, as when the disorder is produced by the effect of the sudden entrance of any very strong vivid or reflected light into die organ. This case Beer denominates ophthalmitis internet idiopathica, proprie sic dicta. The exciting causes, however, may not affect directly the retina, and parts immedi- ately next to if, but may operate chiefly upon the iris, in which event, this part is the chief seal of the inflammation and the complaint i- named both by Schmidt and Beer, iritis idiopathica. This form of inflammation, Beer say-, i seen after the extra*- ion of the cata- r i t, and accidental injuries of the eye, where the w upon, with which they were produced, has either penetrated directly to the iris, and more or less caused it, or roughly entered the eyeball near the ciliary edge of this membrane, without actually wounding it. ( Lehre von den Jingenkrankh. B. 1 ,p. 421.) Symptoms of the first stage of idiopathic internal ophthalmy, properly so called. While a very uneasy sensation of general constric tion and tension affects the whole eyeball, and soon changes into an obtuse, deep throb bing pain, increasing every instant, and quickly propagating itself over the eyebrows to the top of the head, as Beer observes, the power of vision gradually declines, and, at the ‘•arne time, the pupil, which pi only loses i.s dear shining blackness, contracts without bring deprived of its circular figure, or drawn out *it its natural position, until, at length, it i,> so completely closed, that the iris seems as it it had no aperture w hatever. But long before this periect closure of the pupil lias taken place, the power of seeing is entity OPHTHALMY. 437 gone, though after the faculty of perceiving the external light is extinguished, fiery ap- pearances, which trouble the patient serious- ly are seen at each pulsation of the blood- Ves-els within the eye. As the developernent ol these symptoms is going on, the iris evi- dently loses its natural colour, becoming, ns Bo r says, greenish, when it vvas gray, or blue ; and reddish, when its was brown, or black. In consequence of the iris swelling, and projecting towards the cornea, the ante- rior chamber becomes considerably diminish- ed. Immediately the least mark of the swell- ing of the iris is seen, together with a mode- rate degree of contraction of the pupil, the whole sclerotica assumes a pink-red colour ; f» plexus of innumerable blood-v essels is seen in the conjunctiva ; and the cornea loses a good deal of its natural brilliancy, without being actually opaque. The lattersymptoms of this form of ophthalmy are attended with manifest general indisposition, and intolera- ble headach. Sometimes in the first stage of the case, the pupil, though much lessened, is not absolutely closed, but thickish, and if examined with a magnifying glass, it has a red ish-gray appearance, and the power of vision, notwithstanding the continuance of the aperture, is quite lost. (Beer.) Symptoms in the second stage. According to the same author, while the eye is snffernig very irregular throbbing pain, attended with a sensation of heaviness and cold in the eye, an increase of the redoes* of the conjuncti- va, severe constitutional disturbance, and constant shivering, there is suddenly formed at the bottom of the anterior chamber a col- lection of matter which above presents a horizontal line, but on every inclination of the head sideways, changes its position. This matter continues to accumulate more and more, until it not only teaches the pupil, but fills the whole of the anterior chamber, con- stituting the case termed Hypopium. If the disease be left to itself, says Beer, the matter collects in such quantity, that the cornea is rendered more prominent, and afterward conical, very like an abscess, ultimately bursting during an aggravated attack of pain, when the eye shrinks, and the sufferings gra- dually cease. This kind of hy opium Beer names true, in order to distinguish it from the case, in which the matter passes into the anterior chamber out of an abscess in the cornea, and which he terms a false hypopj- um. When, at the end of the first stage, the pupil is not entirely dose.), one may discern in the second slags, at the period of matter presenting itself hi the bottom of the anterior chamber, (though not easily wiilj the unas- sisted eye) whitish filaments, extending from the edge of that opening towards its v-ntie, produced by the coagulahle lymph effused in the aqueous humour, the secretion of which was interrupted in the first stage, but now commences again. And, continues Beer, one may perceive, with a good magnifying glass, a very delicaie cobweb-like mem brane, which, when the matter collected lies over the pupil, and remains fora good while unabso.bed, at length becomes unite ye!- ?ol. IL ~ * -13 low, the matter being really encysted by it in the form of a small lump, which remains in the pupil, nd partly projects into the ante- rior chamber, forming the case, which Beer de nominates a spurious purulent cataract , to which the edge of t lie iris is so closely adhe- rent, that sooner than a separation could be effected, the whole of the iris would be torn in pieces. W en the pupil has been t om- pletely closed in the first stage, these effects of course cannot take place. Beer remarks, with respect to the causes of this form of ophthalmy, tha , as there are not many circumstances which can produce it, the case belongs rather to the less fre- quent kinds of inflammation of the eye. As predisposing, he mentions plethora and irritabilityof the eyes, occasioned by little ex- ercise of them. Experience has convinced him, however, that by far the most usual ca se of this internal ophthalmy is an extra- ordinary, long-continued straining of the eye in the inspection of small microscopic objects in a strong reflected light. Respecting the prognosis, it is remarked by Beer, that this is not unfavourable, when the inflammation of the eyeball is moderate, proper treatmentcan be immediately employ- ed, the pupil is not yet very much contracted, and the power of seeing not considerably impaired. But if the power of vision should seem as it it were abolished, the prognosis is extremely uncertain. And if the pupil should close after the entire stoppage of vision, no hope can he entertained of the recovery of the sight ; for if the pupil open again on the subsidence of the inflammation, it will yet continue very small and motionle-s, and the eye blind. When the case is mistaken in its first s age, and neglected or erroneously treated, Beer says, it changes into a very perilous general inflammation of the whole eyeball ; a disorder already consider' d. In the second stage the prognosis is al~ ways unfavourable; for the eyesight has I- ways been already destroyed at the end of the first one, and the only expectation of t he practitioner can now be to preserve e shape of the eye, while as speedy a check as possible is put to the suppuration. If the case has been so mismanaged in its first stage, that a violent inflammation of the whole eyeball is inevitable, and traces of chemosis are already present, the chances of the figure of the eye being lost in the second stage are still greater, and as Beer observes, the surgeon will be fortunate, if he can now prevent afrigiitful morbid change of the organ. In t he trea inent of the first stage, Beer describes the indications is being exactly the same as in common ophthalmy, except that no scarifications are necessary, unless the case change into a violent inflammation of the whole eyeball. However, great promp- titude in the applica’ ion of proper curative measures is here particularly called for, as the least delay is apt to cau-e either a total loss of sight . or at least a serious impairment off. (Beer.) Wi h tew exceptions, the treatment of the second stage is also !:ka that of ophthalmy OPHTiSALMi. in general. Warm poultices, Beer says, can only he employed with great circumspection. When matter collects in the anterior cham- ber, Beer strongly condemns making an opening in the cornea, hv which practice, he states, tliat th* eye would certainly he ren- dered quite deformed. He recommends leaving every thing to the absorbents, the action of which is to he invigorated hy gene- ral and local remedies. Poultices are now to be laid entirely aside, and the effect of warmth tried. Blisters are to he applied al- ternately behind the ear and on the temple. The eye is to be smeared with the vinous tincture of opium, two or three time- a day, by means of a camel-hair brush, or even four times, when the anterior chamber is filled to the extent of one half of it. Beer’s experience leads him to approve of opening the cornea only in very urgent cases, that is to say, when the eye is so distended with matter, that the cornea is in a state of an ab- scess, which threatens to bur-t. In one part of his observations, Beer describes the mat- ter in these instances as fluid; a point on which he differs from Scarpa: but he alier- ward confesses, that when an opening is practised, the matter mud not he expected to flow out immediately like that of a com- mon abscess For furt'.er information on this subject, see Hyp opium. Idiopathic Iritis. The following is Beer's description ot the disease. Together with an obtuse, heavy, deep pain in the eye. pro- ducing a position, as if the eyeball were continually pressed upon by one of the fin- gers, a manifest and incessantly increasing uniform contraction of the pupil takes place, as well ,v> a gradual diminution of the move- ments of the iris; yet the pupil neither loses its circular shape, nor changes its position in the eye, and at ihesame time, an intolerance q! 1 bt commences. When the pupil is ex- omi ed v ii h a glass, it is found to have al- ready 'os- he shining blackness, which is peculi r to the healthy state. While these changes "curring in the pupil, the col ur ■! the iris undergoes a mate i d altera- tion, first at its le -:«» Ircie, which grows much darker, and afterward at its greater circle, which turns greenisn, i n it was gray or blue, but reddish whet, it wn= brown or black. At the same time, the margin of the pupil becomes mdi !inc»,and ep ( ,ears not so sharp a n eural. A -oon as tin- greater ring of the iris S s under.* me a considerable change of colour, this membrane becomes evidently swelled, nd p, ojects towards the cornea, so hut In- interior chamber is very much lessened. As * !y as the period when th contraction of >h" pu ;'!. and the 1 1 n m > • bilitv of the "i are oh err , »ie, a serious di- minution <>f the p.iwfrr of vision occurs; be- cause, in all cases, the iuflarnmat on extends more or less over the anterior i r of (lie crystalline capsule, and after u ai , the. Case is somewhat m >re advanced, - '■■■> B er, one may perceive quit*- plainly, with he unassisted *ye, those ••ff-, - f infl -intimation on the r.apsub , which live b e so ex<:« I- lentJ|f described by Professor Walt her- (/. lb - handl. aus dan G&bielhe der Vraciist’ttn Me ■ dicin, 1 B. Landshut , 1810.) In proportion a; the inflammation makes progress, the pain grows more severe and exterfsive, and to- wards the end of the first stage, it shoots par- ticularly up to the top of the head; a cir- cumstance strikingly proved whenever any tiling like slight pressure aggravates the pain in the eye. The redness perceptible in the eye during the whole of the first stage is in- considerable, and seems to be not at all pro- portioned to the violence and danger of the inflammation ; for the sclerotica is only of a rose-red colour, and even this pale redness fades towards the circumference of tlie eye- ball (B. 1, p 434.) According to Beer, idiopathic iritis is al- ways attended with a corresponding general disturbance of the system ; but a good deal depends upon whelher the inflammation spends immediately 'o the deeper textures o |f the eye. or to its outer coats, or in both directions at once. In the first case, the constitutional indisposition is always more severe, and the danger of the disease in- creases every moment; in the second in- stance, the augmentation of the general symp- toms is less striking; but in the third, the inflammation, and the corresponding febrile symptoms soon rise to such a pilch that the possibility of preserving the eyesight be- comes very doubiful. The continued ope- ralion of hidden exciting causes, neglect, and erroneous management of the disease, also produce considerable differences ; and, as Beer observes, it not unfrequent ly hap- pens that a genuine idiopathic iritis, which does not appeal* at first very dangerous, nor rapid in its progress, vvi l suddenly change, under the unfortunate concurrence of tfie circumstances, above alluded to, into a com- plete inflammation of the whole eyeball, de- stroying the organ in a tew days, unless the most efficient treatment be speedily adopted. In the second stage, says Beer, in c.o junc- tion with a corresponding still more mani- fest general indisposition, the pain in the eye grows very irregular ; luminous appear- ances flash within the organ, and seriously annoy the patient, especially in the dark, vvhi'e the power of seeing the external light undergoes a great decrease; the redness, even in the conjunctiva, .increase^ ; and the pupil, which hitherto has been perfectly cir- cular, becomes more or less angular. At Miese angles, something of a light grayish co- lour mav be seen projecting behind the pu- pillary edge of the iris, and on examination with a glass, plai* !> appears to be a very de- licate layer of coagulating lymph, by which, fi st the lesser ring of the uvea, and (if pro- per treatment be not expeditiously employ- ed) also its greater ring, are soon rendered adherent to the an'erior po tion • »f 'he cap- sule >1 the lens. ( synechia posterior ,) which membrane, a*- ill di-u a <■ advances, becomes more arid more deprived ol its transparen- cy. Under llie-e circumstance*, it is evident, that the pov\er of vision must dailv decline, and that if this process of the effusion ot lymph and its organization be not jjpvHcd by 0PHTHA1MY 339 powerful measures, (he patient will suon be Heft just capable of faintly distinguishing the light. While the above-described changes an taking place between the uvea at dante- terior position of the capsule, very pec uliar effects are occurring in the anterior cham- ber , for, ns the iris continues to project fur- ther towards the cornea, the latter mem- brane grows less and less transparent, and the iris seems as if concealed in a mist, at the same time that a small, yellowish, red, round prominence is formed at one or more places together, generally hptween the great- er and lesser rings of the iris, and proves af- terward to be a small abscess, which ulti- mately bursting, pours its contents into the anterior chamber, and thus occasions n true Hypopium. For several days, the flakes of (he burst little cyst, still connected with the Iris, may be seen floating in the aqueous hu- mour, until they gradually disappear. When there is not merely one, hut several of these little abscesses, says Beer, the greater part of the anterior chamber may be filled with matter, so that little more of the iris can be distinguished. In weak subjects, at this pe- riod ol suppuration, blood may not unlre- quenlly be perceived in the chamber of the eye ; a circumstance regarded by Beer as a very unfavourable omen, in respect to the recovery of sight, as in such cases, portions of blood and matte: are • pt to lie in the pos- terior chamber entangled in the lymph. Ac- coiding to the same author, the matter in the anterior chamber is at last absorbed ; the pupil, if it has been concealed, can again be seen, but it appears angular and very turbid ; and in consequence ol the layer of lymph in the posterior chamber, the eyesight is ex- ceedingly dimim-hed, or even re dinted to the mere power ot knowing light horn dark- ness Su< h, says Bee , is the course ot the second stage oi idiopathit iritis,, w hen the inflammation has not extended tar beyond its proper locu', and has been principally con- fined to the iris, corpus ciliare, the lens and its capsule, and the anterior part of the scle- rotica. But if it should spread more deeply to the vitreous humour, the retina, the mem- brane Ruyschiana, and the chorotdes, symp- toms ot internal ophthidmy (strictly so call- ed) then occur with great vehemence in the first stage, and at the termination of the se- cond, the eyesight is for ever certainly de- stroyed in such a degree, that not the least perception of light remains ; and even it the patient should think that he can distinguish it, the feel is only a deception ; a develope- ment ol light v\ ithin the eye itself ; of w Inch the surgeon may i usriy assuie himself by placing the patient with his back towards the light, and asking him to point out where it is; or by putting him directly opposite a window, and moving the hand slowly along before his eyes; of which proceeding the patient will be quite unconscious. The ef- fects left in the eye after such an iritis, and indicating its mischievous extension, ate so characteristic, that, on the first inspection of the eye, no surgeon can entertain a doubt of (ha deeper textures of the eye having been involved in the inflammation. But when idiopathic iritis extends rather to the exter- nal, than the deep textures of the eye, the swelled iris, as early as the end ol the first stage, approaches so near the cornea, which grows le.-s and less clear, that they seem as if they were adherent, ere the second stage has commenced. And,- indeed, on the ac- cession of this stage, they actually adhere together at every point, either directly, or with the intervention of a mass of coagula- ting lymph. In the first event, at the end of the second stage, the cornea forms a co- nical protuberance, and a total staphyloma arises ; (se> Staphyloma ;) but in the second, the cornea is said not to undergo this change. On the contrary, it becomes rather flat, and on account of the layer of organized lymph, which fill- up the space between the cornea and iris, little of the Idler membrane can be discerned, and what can be seen, appears to have its organization entirely subverted. When idiopathic iritis in its first stage ex- tends its effects directly over the whol* eye- ball, the eye becomes nearly or quite de- stroyed in the same manner as in cases of vi- olent acute ophthalmy. The causes which give rise to idiopathic iritis, mut always be such as operate direct- ly upon the iris; and, hence, the disorder is usually a consequence of injuries and wounds of the eye, produced by accident, or in operations. And, says Beer, although rheumatic inflammation of the eye, when neglected, or w rongly treated, may at length aff ct the iris, and adjacent textures, yet such an iritis is but a secondary effect, deri- ved from the pre-existing rheumatic oph- thalmy. All injure- in which' the weapon, or in-trumenl, has more or les- pre-sed against, pushed, irritated, < r v iolently brui ed, or torn, the iris itsel,. and ail largish wounds of the cornea, are to tie accoun t'd the prin- cipal exciting causes ot idiopathic iritis. Hem e, extra ion ol the cataract is not un- Irequentlv followed by this i flammation, when t hr flap of the cornea i- kept too long opened, and the iris is hurt with any blunt instrument ; when the incision in the cor- nea is too small, and a hard cataract pushes the iris between I tie lips of the wound, and is slow ly pressed out of the eye ; when many pieces of the cataract break off, and it is ne- cessary repeatedly to introduce Dniel’s scoop for their removal ; or when, notwith- standing the operator proceed with the ut- most delicacy, the patient is excessively timid, and unmanageable, or particularly ir- ritable ar.d prone to inflammation. This torm of iritis is also produced by couching, reclmation through the sclerotica kerato- nyxis, and operations for artificial pupil. Nor, as Beer observes, is it at all surprising, that iritis should follow these last operations, as the surgeon has often to meddle w ith an irid that has been already violently inflamed. Prognosis in the first stage. Serious as the disorder always is; important as the textures are, in which the inflammation is most se- vere ; and quickly as vision may be for ever annihilated by it; yet, says Beer, the prog- OPHTHALMY. mo nosls, in tho first stage, is very favourable, when the true nature of the caso is at once understood, and treated as it ought to be. The prognosis is the most favourable when the inflammation is not extensive ; but it must be very reserved, when the inflamma- tion extends either deeply backward, for- ward, or in both directions. Beer remarks, that, when iritis is purely idiopathic, ami ju- diciously treated in its first stage, it is mere- dible with what rapidity its effects re ede. When it is produced immediately by an in- jury of the iris us if, and some part of this membrane i torn, the risk of the inflamma- tion is not the only thing for consideration ; for the chance of the function oi the iris be- ing permanently impaired by the injury must also be taken into the accoun*. And, says Beer, as in these severe injuries of the eyeball, it is impossible to foretell what may- be the result of the traumatic inflammation, it is a good maxim always either to deter making any prognosis, or to deliv r only a doubtful one. When idiopathic iritis has al- ready changed either into a complete inter- nal ophthalmy, m* into a violent inflamma- tion of the whole eyeball, no incautious pro- mises shonid be made about the recovery of the eyesight, or even about preserving the shape of tbeeje. {Beer.) Prognosis in the second stage. Though, says Beer, this is much les- favourable than in the first stage, yet il proper measures be riot deferred, <> perfect recovery of she eye may often be effected. Here a great deal depends upon the state of the layer of lymph effused in the po-terior chamber, and of sup- puration. If it be plain to the naked eye, that no coagulating lymph lies in that cham- ber behind the contracted pupil, but slight grayish filaments are discernible with a mag- nifying glass, projecting only a little way from behind the pupillary edge of the iris; if the colour merely of the lesser circle of the iris be changed, while no little cyst of matter is yet formed on the latter membrane, a d the sight is lessened only in a small de- gree, being somewhat cloudy ; the com- plaint may be so completely cured by pro- per means, that not a vestige of it wiil re- main. How ever, for some time after theter- jni atiou of the second stage, the motions of the iris will be more sluggish th in natural, though the pupil effectually adapt itsell to the variations of light. On he other hand, when a considers le, though fine, web-like membrane can be plainly seen behind the pupil ; when the colour of the larger circle of tile iris is somewhat altered ; and the power of vision is seriously lessened; though, by effectual treatment, the sight may be re- established sufficiently to enable the patient to read and write; yet, says Ben*, it will for ever continue weak; the pupillary edge of the iris will never regain its perfect free- dom, but constantly remain more or less an- gular ; and the pupil never assume again the clear shining blackness, which in persons not of gr at age it naturally exhibits. Still moie remarkable are the sequelae of idiopa- thic iritis, when a small cyst of matter has been formed on the iris, and discharged- ihr contents into the anterior chamber ; for, in this case, under the best circumstances, the former colour of the iris never entirely re- turns. According to Beer, when at the first visit of the surgeon, vision is quite interrupt- ed by the effusion of lymph in the posterior cha thee so that the patient can no longer perceive any object with the affected eye, though capable of distinguishing the light, and th>* outlines of - 59.) Mr. Hunter entertained doubts, whether any inflammations of the eyes are syphilitic, and he appears to found his opinion upon two circumstances ; one is, that, if such cases be venereal, the disease is very diffe- rent from what it is when it attacks other parts, and is attended with more pain than venereal inflammation, arising from an af- fection of the constitution : the second is, that he never sa these cases, attended with such ulceration, as occurs when the com- plaint invades the mouth, throat, and tongue. (Hunter on the Venereal Disease, p. 324.) On the other band, the generality of modern surgeons believe in the reality of venereal ophtiialmy, though their accounts of the symptoms and appearances of the com- plaint are in some respects discordant. Scarpa says, the venereal ophthalmy is pe- culiar in not discovering manifest signs of inflammation, stealing on clandestinely, without much uneasiness. It afterward re- laxes the vessels of the conjunctiva and lining of the palpebrse, and changes the se- cretion of Meibomius’s glands. In time it causes ulceration of the margins of the eye- lids ; the ciliae fall off, and the cornea grows opaque. In the worst stage it excites itch- ing in the eyes, which is exasperated at night, and abates in violence tow ards morn- ing, as do almost all the effects of syphilis. It never attains the state of chemosis. With the exception of the venereal oph- thalmy, in the form of iritis, 1 cannot dis cover, that any thing very certain has yet been made out. By this observation, how- ever, it is not meant to assert, that cases, corresponding to Scarpa’s description, do not present themselves, and may not be relieved by his method of treatment ; but, that their venereal character is not fairly proved. In examples, like those described by Scarpa thedecoct.sarsap.theqxymuriaie of mercury ; mezereon ; guaiacum ; and even mercurial frictions, may be employed, with leeches and blisters. Scarpa particu- larly recommends a collyrium, made with the oxy muriate of mercury. When the eyelids are ulcerated, the unguenturn hv- drargyri nitratri, weakened at first with twice or thrice its quantity of the unguenturn ce- taepurn, is the best topical application. The iris is now supposed to be more lia- ble than any other part ot the eye, to vene- real inflammation. ( Wardrop's Essays era the Morbid Anat. of the Eye, Vol 2, p. 36.) The case is mentioned by Mr. Sounders, who recommends the vigorous exhibition of mercury, and the use of belladonna. Us symptoms and treatment, however, have been more particularly detailed by Beer. (Lehre von den Augenkr B. 1, p. 553.) As this case, and some other specific forms of iritis, are described in the first vol. of the last edition of the First Lines of Surgery, 1 need here only refer the reader to that volume, and to a few works containing ad- ditional information on iritis in general; aat Sounder's Treatise on some Practical Points, relating to Diseases of the Eye p. 21,8t'o. 1811 ; and particularly the latter editions, in which the utility of mercurials is noticed. Beer's Lehre von den Augenkr. B. 1, 8ro, Wien. 1813. In the article Hypopium , I have referred to an early case, in which the quick exhibi- tion of mercury and its good effects were exemplified in Germany. But whatever claims the continental surgeons may have respecting the first administration ot mer- cury in iritis, 1 believe it a justice due to Dr. Farre and Mr. Travers to state, that these gentlemen have undoubtedly given notonly the best practical directions on the subject, but laid the greatest s ress upon the neces- sity of the practice, establishing the efficacy of mercury, as a means as well of resisting the effusion of lymph in the eye, as of exci- ting the absorption of it, after it has been effused. (See Travers, in Surgical Essays, Part l.) Consult also J. l etch , A Practical Treatise on the Diseases of the t.ye. p. 88, fyc. S vo. Lond. 1820. Weller’s Manual of the Diseases of the Human Eye, Trans by Mon- teath, 8 vo. Glasgow, 1821. J. War drop j Morbid Anatomy o the Eye, Vol. 2, chap 20, 8 vo. Lond. 1818. H. B. Schindler, de Jrilide Chronica, Vralislacice, lb 19. J. A. Schmidt liber Nachstaar und Iritis nach Staar - Opera ionen, 4 to. Wien. 1801 ; a work of high repute. Carmichael in Obs. on the Spe- cific Distinctions oj Venereal Diseases, p. 31* Quarterly Journ. of Foreign Medicine , JYov. 1818. Rheumatic Inflammation of the Eye. Ac- cording to Mr. VVardrop, the albuginea ac- quires a brick-red tinge, or an admixture of yellow w ith crimson red, which colour, be supposes, is probably caused by the serous part of the blood being tinged with bile* “ an effect, likely to take place from the marked derangement of the biliary organs, which usually acco • panics this disease.” Contrary to the statement of Beer, who de- scribes the blood vessels as being in clusters, Mr. Wardrop observes, that they are gene- rally equally numerous over the whole white of the eye, passing torwards in near- ly straight lines from the posterior part ot the eyeball, and advancing close to the cor- nea ; but neither passing over it, nor leaving the pale circle around it, which is so striking when cither the choroid coat, or the iris k OPHTHALMY. unilaraed. If the v essels be closely examin- ed, the general redness will be found produ- ced more by numerous small ram ideations, than a few large trunks. There is frequent- ly a little swelling of the conjunctiva, which sometimes forms a slightly elevated ring round the cornea. In mild cases, little change takes place in the anterior chamber in the early stage ; but, as the disease ad- vances, the cornea becomes dull and turbid. Upon close examination, one or more of the layers of the conjunctiva on the cornea will generally be found to be abraded espe- cially towards its circumference. At the commencement of the disease, there is of- ten a disagreeable feeling of dryness of the eye ; but sooner or later, a very copious secretion of tears takes place. The eyelids are observed to be very little affected. At first, the chief seat of pain is generally in the head, though sometimes in the eyeball itself. Mr. Wardrop describes the pain as usually most severe in the temple of the af- fected side, but, he says, that it is often seat- ed in the brow, the cheek-bone, the teeth, or the lower jaw. “ Sometimes the pam is precisely confined to one half of the head, and sometimes there is a severe pain in the cavity of the nose, or in the ear. The pains are more of a dull agonizing kind, than acute, and though unceasing, they vary much in degree, coming on at times in very severe paroxysms, and with great violence, when the head is bent downwards. Some- times the pain is excited by merely touch- ing the scalp, and the patient is unable to rest his head on the affected side, or even lean it on a pillow. In most cases, the pain is said to be remittent, the paroxysm coming on in the evening, continuing during the night, being most severe about midnight, and abating towards morning. In the eyeball, says Mr Wardrop, the pa- tient generally complains more of a sense of fulness and distention, than of pain ; and, though there is a great degree of external redness, the eye does not seem to suffer from ex- posure to light ; a point, on which Professor Beer delivers a directly opposite statement, at least, in relation to the first stage of the disease. However, these authors both agree in considering the sclprotica, as generally the chief seat of rheumatic inflammation ; but Beer sets down the iris as likewise a subject to be attacked. He admits also, that in the second stage, the aversion to light under- goes a considerable diminution According to Mr. Wardrop, rheumatic ophthalmy is always accompanied with more or less symntomatic fever, severe paroxysms of which take place toward evening, and the functions of the prim® vise are much de- ranged, “ the appetite being impaired, and the evacuation always changed in quality.” In severe cases, the pain in the head soon becomes agonizing, the r^d mss of the eye- ball increases, the whole white of the eye is crowded with blood vessels, and the con- junctiva swelled. At length ulceration com- mence* in the cornea, through which the aqueous humour is discharged, and the eye- ball collapses, when all pain ceases ; or abscesses may form within the posterior chamber, and burst through the sclerotic coat. ( Wardrop , in Med. Chir. Trans Vol. 10.) Beer describes small watery vesicles as forming on the cornea, or white of the eye, and changing during severe pains into small ulcers, which occasion an appearance, as if a small piece were torn out of the sur- face of the cornea. He adds, that they seldom leave scars behind ; but generally little pits, which are soon filled up in healthy subjects. (See Weller on Diseases of the Eye, Vol. 2, p. 217.) The causes of rheumatic ophthalmy. enu- merated by writers, are change of weather, vari ation of temperature, exposure to damp, a cold current of air directly striking the eye, and a constitution disposed to rheuma- tism. Mr. Wardrop states, that both sexes are equally subject to the disease ; but that he has observed it most frequently in adults, and persons of rather advanced age. Only one eye is usually affected ; and when the second is attacked, the disease is almost always less severe in it, than that which is first inflamed. According to Mr. Wardrop, rheumatic ophthalmy resembles syphilitic more than any other kind of inflammation of the eye. But, he notices, that, in rheumatic ophthalmy , th° proper vessels of the sclerotic coat are enlarged, which is the cause of the redness being generally diffused over the whole albuginea, whereas in syphilitic inflammation, it is the anterior ciliary arteries , passing along the sclerotica on thnr way to the iris , which are ch efiy affected ; and hence the pale ring, which is always observed between the cor- nea and the enlarged vessels. Mr. Wardrop further explains, that though these diseases resemble each other in the pains round the orbit, and their evening exacerbation, pa- tients , with syphilitic ophthalmy. aluays have the constitutional symptoms of syphilis. When the disease has made much progress, and the symptoms have not yielded to other remedies, Mr. Wardrop recommends the evacuation of the aqueous humour, as a prac- tice, from which the most beneficial effects may be expected. After the operation, fo- mentations are the only necessary applica- tions ; but, if the eye continue long irritable, the vinous tincture of opium is to be used. Mr. Wardrop enjoins attention to the state of the biliary organs in every stage of the disease, and speaks highly of the sudden relief sometimes afforded by an emetic, care being taken to empty the bowels afterward with calomel and rhubarb, or other purgatives. If t ie functions of the skin were suddenly interrupted by a -hill just before the attack, this author prescribes a couple of grains of aniimoniai powder, alone, or combined with opium, to be taken every four or six hours. Little advantage, ne says, is derived from local bleeding, and where venesection may become necessary, on account of the com- plaint resisting other means, it to be prr.c ti c ed with moderation 344 OPHTHALM**. In the early stage, Mr. Wardrop has found, that the pain in the eye and eyebrow are sometimes much alleviated by a fomentation with the decoction of poppy-heads. He also praises blisters to the nape of the neck, or behind the ear; but, disapproves of their being put near the eye itself. The vinous tincture of opium, he says, is the only local application which he has ever seen deci- dedly beneficial ; but, its use is to be deferred, till a late stage of the inflammation, when all febrile symptoms have been subdued. “ After the primae viae have been well evacuated, the tongue may still remain very white, and the pulse quicker than natural.” In this state, small doses of bark, either alone, or with the mineral acids, will be most serviceable. ( Wardrop in Med. Chir. Trans. Vol. 10.) The outlines of Beer’s practice may be given very briefly : in the first stage, he applies a leech to the inner canthus, and covers the eye with a cold poultice, with a small proportion of vinegar in the water, with which it is made. Diaphoretics are also prescribed. In the second stage, guaiacum, camphor, arnica, antimonials, blisters to the neck, or behind the ears, frictions with opium over the eyebrows, and covering the eyes with bags of aromatic herbs and cam- phor, are the means of the relief. When abrasions, or ulcerations exist on the con- junctiva, sclerotica, or cornea, a collyrium of the lapis divinus. with a large addition of the vinous tincture of opium, is commended ; or if the ulcers are large, and on the cornea itself, they may be touched with the latter tincture by means of a camel-hair pencil. After each use of the collyrium, Beer covers the eye again with the bags of aromatic herbs and c .mphor. (See Weller on Diseases of the Eye, Vol. 2, p. 218.) Respecting the last application, I have already expressed my belief, that it is one which is not likely to obtain credit among English surgeons. Scrof l ous Ophthalmy. According to Mr. Travers, the inflammation of the conjunctiva, termed strumous, when it has not proceeded to a eba* ge of texture, is not marked by any prominent local character.” The vascularity is inconsiderable This inflammation some- times accompanies pustule of the sclerotic conjunctiva, in which case, the vascularity is diffused, instead of being partial, as in pure puslular inflammation, and the intole- rance of light, characteristic of ike strumous inflammation , is present in a greater or lesser degree. It accompanies also (he morbid secretion of the lids, when the eyeball becomes affected by the acuteness and dura- tion of that disease, and the pustule on the cornea, especially the variolous pustule. In its simplest form, it is almost peculiar to voting children, stationary, marked by a very slight redness of the sclerotic conjunc- tiva, and the greatest possible degree of intolerance (of light ”) The same author attributes the disease to n morbid sympathy of the retirm with the secreting surfaces of he primae vice and skin. The following is *he treatment proposed by Mr. Travers for each form of scrofulous ophthalmy ■ 1. Strumous inflammation, without chaugt of texture, vascularity more or less, intole- rance (of light) excessive. Calomel and opium, at night ; emetic tartar to continued nausea , gentie alvine evacuants ; diaphoretic drinks ; large open blister on the nape of the neck ; leeches ; tppid bath ; tepid or cold water washes, as must agreeable ; vapour of opium ; large bonnet shade ; no bandages ; spacious airy apartments ; and light bed-clothing. 2. With recent diffused opacity of the corneal conjunctiva , and vessels raised upon and over- shooting the corneal margin. Calomel and opium to slight ptyalism ; purgatives on alternate days ; leeches; blisters alternated behind the ears and on the nape of the neck and temples. As the acute stage passes off, repeated circular sections of the vessels on the sclerotica, near the margin of the cornea. 3. With herpetic ulcers of the corned. The same ; blisters on the temples ; as the in- flammation yields, solut. argent, nitrat.; vin. opii ; solut. cupr. sulph. ; dilute zinc lotion. 4. With pustules. If partial, weak zinc, or alum lotion ; ung. hydrarg nitrat. ; occa- sional brisk purgatives ; infusion of roses with additional acids ; tonic bitters ; colum- ba ; gentian, he. blisters behind the ears, repeated if necessarv ; if the vascularity is diffused by the multiplication of pustules, or the duration of inflammation, with irrita- bility to light, treatment as in strumous in- flammation without breach. Ung. sub-acet. plumbi. 5. With inflammation of the follicles and puriform discharge. Active measures at first, but not long continued. Blisters; when be- coming chronic, with thickened lids, scarifi- cations ; zinc, alum, or copper wash, dilute ; ung. hydr. nitrat.; hydr. nitr. oxid.; sub-ncet. cupri ; tonics and sedatives ; if obstinate, issue or seton. 6. Convalescent state. Infusion of roses ; cas- carilla ; columba ; decoction of bark . with dilute sulphuric, or nitric acid : steel, rhu- barb, and soda ; or magnesia, as aperients ; tonic collyria and gently stimulant oint- ments; nutritive diet ; country air ; shower, or sea-balh, in the warm months. (Travers's Synopsis, fyc. p. 92 — 260, fyc. When I look at the discordant accounts of what are called scrofulous affections of the eye, and the difference of practice laid down by different writers I leave the subject with an impression, that the terms scrofu- lous and strumous are here employed as much at random as in any other cases, which ran be specified. Indeed the attempt to recon- cile the various statements and descriptions of scrofulous ophthalmy, would puzzle the most able man in the profession : and it is with this belief, that I avoid contrasting the sentiments of Beer, Weller, Lloyd, and other modern writers with those already de- livered. (See particularly Beer's Lehre vou den Augenkr. B. 1, p. 588- fyc.; Weller's Manual of the Diseases of the Eye , Vol. 2, p. 265, <^c. ; and Lloyd on Scrofula , p. 312, <^c.) The following observations explain the Practice of Scarn?. and the late Mr. Wan* OPHTHALMY. Sip No specific being known for scrofula, the treatment, in this instance, rather con- sists in preventing the aggravation, than in attempting the radical cure of the complaint. Every thing debilitating is hurtful, as all evacuations ; indigestible food; intense study ; a sedentary life . damp marshy habitations ; uncleanliness ; frequent transitions from heat to cold. On the other hand, observing to regulate the action of the bowels with the mildest laxatives ; and the administration of bark, either alone or conjoined with the tinct. guaiaciammoniata,do good. Alterative medicines, and especially aethiops mineralis, from gr. ss. to gr. xx. in the day, taken for a few weeks uninterruptedly ; liquor calcis, in broth or gruel, at first, in the dose of Jiij. at breakfast, and atterward the same quan- tity, twice daily for a few months ; together with the uniform observance of a good regi- men ; may tend much to abbreviate the du- ration of this obstinate species of the dis- ease. (Scarpa.) Mr. Ware found, that the addition of xx to xxx gr. of the potassai sulphas to each dose of bark, suffices to keep the bowels in a re- gular state, when there is a tendency to cos- tiveness. In some cases, in which there was little appearance of inflammation, this gentleman found the eyelids so relaxed, and the eyes so irritable, that children would not open their eyes, even in the darkest room. In some of these relaxed cases, very benefi- cial effects were produced by administering internally small doses of opium, night and morning, to abate the irritability. Sea-bath- ing is always serviceable in scrofulous oph- thalmy, and, probably the mere residence on the seacoast, and the respiration of the sea- air, may bring about some of those advan- tages, which have been exclusively, attri- buted to bathing. Friction of the body with a fresh brush or flannel, should be employed morning and evening. With regard to topical applications, those of a soft relaxing kind prove injurious, as also retirement in dark situations. Slightly astringent collyria ; the ung. tutiag, and the ung. hyd. nitrat. are proper when there are excoriations upon the eyelids, and when, from their occasional adhesion to each other, there is reason to suspect, that the sebaceous gffinds secrete an acrimonious fluid. Mr. Ware also found that one drop of the thebaic tincture, dropped into the eye, once or twice in the course of the day, contributed greatly, both to abate the irritability and to increase the strength of the relaxed vessels. (On Scrofulous Ophthalmy p. 26.) The same gentleman occasionally mixed old verjuice with cold spring- water, at first, in the pro- portion of one part of the former to six of the latter, and sometimes increased the quantity of verjuice, until its quantity equal led that of the water. All coverings should be removed from the eyes, except a shade of green silk, and patients should be gradually habituated to a stronger light. Good air and exercise always tend to im- prove scrofulous constitutions, and thus, V'jj, u 44 indirectly, the disease under consideration. Scrofula often disappears spontaneously, as children approach the adult state, and, if we only have it in our power to check its progress in the early stage" of life, it seems to wear itself out afterward, and whatever local effects it may have produced, often disappear Chronic Ophthalmy. Unfavourable pecu- liarities are met w'ith in practice, which prevent the complete cure of the second stage of acute ophthalmy, or that connected with a weak vascular action in the part affected ; whence the protracted disease becomes purely chronic, and threatens the slow destruction of the eye. These peculiarities may be chiefly re- ferred to three causes : 1. To an increased irritability continuing in the eye after the cessation of acute inflammation. 2. To some other existing affection of the eye, or neighbouring parts, of which the chronic ophthalmy is only an effect. 3. To consti- tutional disease. 1. That chronic ophthalmy may depend upon a morbid irritability of the eye is evinced, not only from its resisting topical astringents and corroborants, to which the disease from simple relaxation and weakness yields, but from its being exasperated by them, and even by cold water. The patient complains of a sense of weight in the upper eyelid, and restraint in opening it ; the con- junctiva has a yellowish cast, and when exposed to the damp cold air, or a brilliant light, or wffien the patient studies by candlelight, its vessels become injected and turgid with blood. If, in combination with such symptoms, the habit of body be weak and irritable ; subject to spasms ; hypochondriasis, &c. then, it is manifest, that the chronic ophthalmy is connected with a general impairment of the nervous system. 2 Besides extraneous bodies, lodged be- tween the palpebras and eyeball, the inver- sion of the ciliae and hairs, growing from the caruncula lachrymalis ; ulcers of the cornea ; prolapsus of the iris ; herpetic ulcerations of the margins of the eyelids ; a morbid secretion from the Meibomian glands ; a diseased enlargement of the cor- nea, or of the whole globe of the eye, &c, may occasion and maintain chronic ophthal- my. — it is only my part here to mention such remote causes ; for, the particular treatment of them is described in other articles. (See Cornea , Ulcers of; Iris, Prolapsus of ; Lippi - tudo ; Staphyloma ; Hydrophlhalmy ; Tri- chiasis, fyc.) 3. The cure of thp second stage of acute ophthalmy may be retarded by the preva- lence of scrofula in the system ; or by the small-pox affecting the eyes. According to Scarpa, chronic ophthalmy isalso sometimes a consequence of lues venerea; but l know* nothing certain on this subject, in addition to what has been stated in the foregoing columns. When chronic ophthalmy depends upo'n OPHTHaLMY. 316 preternatural irritability, the internal exhi- bition of bark with valerian is proper ; animal food of easy digestion ; gelatinous and farinaceous broths; wine in moderation ; gentle exercise; living in salubrious and mild situations ; are all severally productive of benefit. Externally , the applications should be of a sedative and corroborant kind ; such as aromatic spirituous vapours (from the spiritus ammon. comp.) applied to the eye through a funnel, for half an hour, three or four times a day ; and the eyelids and eye- brows may also be rubbed with the linimen- tutn camphors?. Patients, both during the treatment and after the cure, must refrain from straining the eye, and, immediately the least uneasi- ness is felt, must desist from exercising it. When they write or read, it should con stantly be in a steady, uniform light, and too little, as well as too much exercise of the organ, aggravates the disease. Having once begun to wear spectacles, they should never study orsurvey minute objects without them. {Scarpa.) Intermittent Ophthalmy. It is the charac- ter of certain forms of ophthalmy, like the rheumatic and venereal, to be liable to periodical exacerbations ; but I am not certain that there are any cases specifically claiming the name of intermittent ophthalmy . The late Mr. Ware, however, ha- noticed some examples, which intermitted, or at least, remitted at stated periods. In these, he did not find bark so useful, as in scrofu- lous ophthalmy; but he had seen the most beneficial effects produced by the oxy mu- riate of mercury, sometimes joined with the compound decoction of sarsaparilla. (See IVare on Intermittent Ophthalmy .) Variolous Ophthalmy . As the small pox inoculation has at present almost generally been abandoned by the faculty in favour of the vaccine disease, there seems less occasion now for detailing circumstantially a very obstinate species of ophthalmy, induced by the former complaint. When the small-pox eruption is very abundant in the face, it causes a considerable swelling of this part of the body ; the eyelids become tumefied, the eyes redden, and there ensues a dis- charge of a very thick adhesive matter, which agglutinates the palpehra? together ; so that if no steps be taken, the eyes will continue closed for several days in succes- sion. The matter, confined between the eyelids and globe of the eye, being per- haps of an irritating quality, and injurious from the pressure it occasions on the sur- rounding parts, seems capable of exciting ulceration of the cornea, and even of irre- mediably destroying vision. When the pustules of the small-pox in other parts of the body have suppurated, they cicatrize ; but those, which happen within the margin of the cartilage (if the eyelids, are prevented from healing by the diseased secretion, which is then made from the Meibomian glands, and such ulcers result, as will some- titpes last for several years, and even during life, if unremedied by art. {St. Yves sur Us Mai. des Yeux, p. 216, Edit. 12 mo.) After the employment of the antiphlogistic treat- ment. should the disease, when treated with topical astringents and corroborants, yet baffle the efforts of the surgeon, setons in the nape of the neck, kept open for a long while, prove one of the most useful reme- dies. Scarpa has experienced much advan- tage from giving every morning and evening, to a child, ten years old, a pill, containing one grain of calomel, one grain of thesulph. aur. antun. and four grains of cicuta in powder. It is obvious, that so potent an alterative, if ever serviceable in this case, will soon evince its efficacy ; nor would it be justifiable to sport with the patient’s constitution by continuing its use beyond a certain period, unless sanctioned by evident signs of its salutary effects on the disease of the eyes. When great irritability prevails, a mixture of three drams of the vinum antimoniale, and one dram of the tinctura thebaica, given in doses of five or six drops, in any convenient vehicle, and at the same time, applying externally the vapours of the spiri- tus amnion, comp, to the eye, constitute an excellent plan of treatment. In othei cases, saturnine collyria, with a little camphorated spirit of wine, or white wine, in which a little sugar is dissolved ; tinct. thebaica ; Janin’s ointment. &c. avail most. This treatment is also applicable to the chronic ophthalmy from measles. - When inveterate ulcers remain upon the edges of the palpebral, the disease may then be regarded as the psorophthalmy, described by Mr. Ware, and will demand the same method of cure. (See Psorophthalmy.) Operation of discharging the aqueous hu- mour. To this practice, some allusion has been already made in the preceding co- lumns ; and as the proposal is intended to apply to several forms of inflammation of the eye, 1 have not given any particular account of it in treating of the various cases. Mr. Wardrop remarked, that if the eye of a sheep, or ox, be squeezed in the hand, the whole cornea instantly becomes cloudy, and whenever the pressure is removed, this mem- brane regains its transparency. From this cu- rious phenomenon in the dead eye, it was evi- dent that, in the living body, the transparen- cy of the cornea might vary according to the degree of its distention ; and that, in cases of opacity of the cornea, accompanied with fulness of the eyeball, its transparency might be restored by the evacuation of the aque- ous humour. The cornea is little sensible, and, as every body knows, its wounds are free from danger. Mr. Wardrop soon met with a case, favourable for making the experiment; the cornea was milky and opaque, and the eyeball distended and pro- minent, attended with acute inflammatory symptoms. The aqueous humour was dis- charged by a small incision, and the operation produced not only a removal of the cloudiness of the cornea, but an abatement of the OPHTHALMY. 347 pain, anda sudden check to ail the inflamma- tory symptoms. From the successof this case, Mr. YVardrop was led to perform the opera- tion on others, not only with a view of diminishing the opacity of the cornea, but also of alleviating the inflammation. Four interesting cases are related by this gentle- man, very much in favour of the practice, when the eye is severely inflamed, attended with fulness of the organ, a cloudy state of the cornea, and a turbidness of the aqueous humour. Mr. YVardrop also advises fhe ope ration, whenever there is the smallest quan- tity of pus in the anterior chamber, ac- companied with violent symptoms of inflam- mation. He thinks, that the great and im- mediate relief, which the method affords, is imputable to the sudden removal of tension ; and he performs the operation with a small knife, such as is used for extracting the cataract. The instrument is to be oiled, and introduced so as to make a wound of its own breadth, at the usual place of making an incision in the extraction of the cataract. By turning 1 the blade a little on its axis, the aqueous humour flows out. (See Edinb Med. and Surg Journal. Jan. 1807 ; also Med. Chir. Trans. Vol. 4.) The late Mr. Ware approved of Mr. YVardrop’s operation in the epidemic , purulent , or Egyptian oph- thalmy , when, notwithstanding general eva- cuations topical bleeding, mildly astringent lotions, and a strict antiphlogistic regimen, the symptoms still continue, and especially if the cornea begin to lose its transparency, and a white rim appear round its circumfer- ence. Mr. Ware did not object to using a small knife, of the kind employed in extract- ing the cataract ; but preferred a lancet, or a sharp-pointed couching needle, w r ith a blade somewhat wider than usual, and a groove in its middle. The instrument, he advises, to be introducedabout one-tenth of an inch before the connexion of the cornea with the sclerotica, and pushed gently on, parallel to the plane of the iris, until the aque- ous humour makes its escape. ( Ware on the Purulent Ophthalmy, p. 41, 1808.) As alrea- dy explained, Mr. YVardrop also recommends this practice in certain states of rheumatic oph- thalmy. Consult Avicenna, Canon L. 3, Fen. 3, Tract. 1 , cap. 6. Maitre-Jun Traite des Mai . de VCEil, 12 mo Paris 1722. St. Yves , Traitd des Mai. des Yeux, p 170, fyc. Janin, Mem sur VCEil. fyc. 8 vo. Paris , 1772. L F. Gendron , Trait 6 des Mai. des Yeux . 2 T. 12mo Paris , 3770. C. F. Reuss, Dissertation es Med. Selectee Tubingenses Oculi Humani Affect us Medico- chirurgice consederatas sislenles, 3 Vo Is. 8 vo. Tub. 1783. Trnka de Krzowitz, Hist Ophthal- mia omnis aevi observata medica continens, 8ve. Vindob. 1 783. G. Power, Attempt to investigate the causes of the Egyptian Ophthalmy; with obs. on its nature and cure, 8 vo. Load. 1803. H. Read, An Essay on Ophthalmia, 8vo. Portsea , 1806-7. J. B Serney, Treatise on Local In- flammation, more particularly applied to Dis- eases of the Eye, fyc. 8 vo. Land. 1809 J. P. Marat, An Inquiry into the Nature. Cause, and Cure of a singular Disease of the Eyes, hitherto unknown , and yd common, produced by the use of certain mercurial preparations , 4lo. Land. 1770. James Ware, Chir. Ob- servations relative to the Eye, 2 Vols. 8vo. Loud. 1805. Richter, Anfangsgr. der Wun- darzn. B. 3. G. Peach and J. Wardrop in Edinb. Med. Surg. Journ.for January, 1807. Also J. Wardrop, in Med. Chir. Trans. Vols. 4 and 10; and Essays on the Morbid Anatomy of the Eye, 2 Vols. 8 vo. 1808 — 1818. John Vetch , An Account of the Oph- thalmia, which has appeared in England since the return of the British Army from Egypt , 8 vo. Loud i807. Also Obs. relative to the Treatment by Sir Wm. Adams of the Oph- thalmic Cases of the Army, 8 vo. Loud. 1818. Letter on the Ophthalmic Institution for the Cure of Chelsea Pensioners, 4to. Lond. 1819. And A Practical Treatise on the Diseases of the Eye, 8 vo. Lond. 1820. W. Thomas, Obs. on the Egyptian Ophthalmia, and Ophthalmia Purulenta, 8 vo. Lond. 1805. P. Assalini on the Plague, Dysentery, and Ophthalmy of Egypt, &/-c. Transl. by A. Neale, Lond. 1804. Also Manuale di Chirurgia, 8 vo. Milano , 1812. F. Vasani Sloria daV Ottalmia con- tagiosa dello Spedalt Mililare d' Ancona, 8vo. In Verona, 1816. Also Risposta a do che la riguarda nei Cenni del D, f. Omodei sulV Ottalmia d'Egitto et sulla sua propagazione in Italia, 12 mo In Verona, 1818. T F Balfz, de Ophthalmia Catarrhali Bellica, 4 to. Hei- delb. 1816 Arthur Edmonstone, A Treatise on the Varieties and Consequences of Ophthalmia , with a preliminary inquiry into its conta- gion nature, 8 vo. Edinb. 18(»6. De Wenzel , Manuel de VOculiste , 2 T Svo. Paris, 1808. C. Farrell, On Ophthalmia and its conse- quences. 8vo. Lond. 1811. On the Utility of Blisters in the Ophthalmia of Infants, in Ed. Med. Surg. Journ. No. 58, p. 156. R. C. Graefe, Journ. der Chir. B. 1. Also Re- pertorium augenarzlicher Heiformeln , 8 vo. Berlin , 1817. G. Benedict, De Morbis Oculi Humani Inflammatoriis, 4 to. Lips. 1811 J. C. Saunders on Same Practical Points re- lating to Diseases of the Eye, edited by Dr. Farre, Lond. 181 1, or rather the later editions. Karl Himly Ophthalmologische Beobachtun- gen, fyc. 12»i0. Bremen, 1801. Also his Ein- leitung in die Auge nhtilkunde, 12 mo. Jena , 1806, and his Bibliothek fur Ophlhalmologie , fyc. 12 mo. Hanuov. 1816. F. J. Wallroth , Syntagma de Oahihalmologia Veterum, 8 vo. Halve , 1818. C. J M. Langenbeck in Bibl. and Neue Bibl. far die Chirurgie, in various places. Ant. Scarpa, suite Principali Malatiie degli Occhi ; Venez. Ediz. 5ta. : or the Transl. by Mr. Briggs 2 d Ed. Roux, Voyage fait tn Angleterre en 1814, ou Parallele de la Chirur- gie Angloise avec la Chirurgie Francoise, p. 37, <^c. P. M l Gregor in Trans of a Society for the Improvement of Med and Chirurgiral Knowledge, Vol. 3, p. 30 fyc. Larrey, Me- moiresde Chir Militaire, T. 1 ,p. 202, fyc. A. Schmidt, iiber Nachslaar und Iritis, 4to. Wien. 1801. G. J. Beer, Lehre von dem Augenkrarikheiten, 2 B. 8 vo Wien. 1813-~ 1817. C. H Weller, A Manual of the Di S r eases of the Human Eye, Transl. with Notes by G C Monteat h, 2 Vols Svo. Glasg. 1821. B. Travers on Iritis , in Surgical %s$ays } 348 OSTEOSARCOMA Part 1. Also a Synopsis of the Diseases of the Human Eye , Svo. Loud. 1820. Eusebius A. Lloyd on Scrofulous and Purulent Oph- thalmia , in a Treatise on Scrofula , Svo. Lond. 1821. OSCHEOCELE, (from oer%eov, the scro- tum, and km a tumour.) A hernia which has descended into the scrotum. *OSTEOSARCOM A, or Osteosarcosis. (from oo-Ttov, a bone, and era />%, flesh.) This term signifies the change of a bone into a substance, of the consistence of flesh. Bones are sometimes converted into a soft, lardy, homogeneous substance resembling a can- cerous gland, and it is this affection, to which Boyer thinks, that the appellation ought to be confined, Callisen seems also to regard the osteosar- cosis as a disorder by which the texture of the bones is converted into a fleshy or fatty substance, accompanied with a tendency to carcinoma. ( System . Chirurgice Hodiernce , p. 204. Vol. 2. Edit. 1800.) We are to un- derstand by osteosarcoma, says Boyer, an alteration of the osseous structure, in which, after more or less distention, the substance of the bone degenerates, and is transformed into a diversified mass but, more or less analogous to that cancer of the soft parts ; while the local and general symptoms still more strikingly resemble those of the lat- ter disease. (See Traite des Mol. Chir. T. 3, p. 587.) According to this writer, all the bones are liable to such a disease ; but it has been more frequently observed in the bones of the face, those of the base of the skull, the long bones of the limbs, particularly the ossa irinorninata, which are perhaps oftener affected than any other bones of the body. {Op. cit. p. 588.) Foreign surgeons do not appear to enter- tain precisely the same ideas respecting cancer, which prevail in England : at least, they apply the term to many complaints in which there are no vestiges of a carcinoma- tous structure, and numerous diseases of an incurable nature receive abroad very indis- criminately the name of cancer. Thus, the French surgeons have not yet distinguish- ed the strongly marked differences between carcinoma and fungus haematodes (See JRoux , ParalWe de la chir. Angloise, fyc. ; and the article Fungus Hcematodes.) Fungous diseases in the antrum expand the bones of the face, make their way out, and present a frightful specimen of disease. This change of the bones, though known to have nothing to do with cancer, (see An- trum,) is considered by Boyer as a kind of osteosarcoma, proceeding from carcinoma- tous mischief in the neighbouring soft parts ; and this he adduces as an example of his first species of osteosarcoma, or that arising in consequence of previous disease in other parts. In the second species, the disorder commences in the bones, and the soft parts are secondarily affected. In all cases, osteosarcoma comes on with deeply-seated pain, which sometimes lasts a considerable time before any swelling is manifest. Some- times the pain becomes more and more afflicting, and of the lancinating kind, im pairing the health even before there is any change in the form of the limb. At length, the swelling takes place, occupying the whole circumference of the member. Its nature and situation are in some measure indicated by its hardness and depth. It is unequal and tuberculated, as it were. Pres- sure does not lessen its size, nor make the pain worse. The soft parts are still in their natural state. The tumour, however, grows more or less rapidly and the lancinating pains become more severe. In time, the soft parts themselves inflame, and become painful. Sometimes, the skin ulcerates, and, in this very uncommon case, the sore pre- sents a cancerous appearance. Hectic symptoms are induced, the patient gradually loses his strength, and, at length, falls a vic- tim to the disease. The alteration, which the structure of the bones undergoes in the osteosarcoma, (says Boyer) deserves great attention. Most frequently, when the disease has made con- siderable progress, and the tumour has exist- ed a long while, the bony texlure has disap- peared more or less completely ; in lieu of it, an homogeneous grayish, yellowish, lard- like substance is found, the surface of a slice of which is smooth, much like that of a very hard white of egg, or old cheese, the consistence varying from that of cartilage to that of very thick bouillie. The sur- rounding soft parts, which have participated in the disease of the bones are converted into a similar matter; muscles tendons, periosteum, ligaments, vessels, cellular sub- stance, all are confounded in the same homogeneous mass, and have undergone the same degeneration. In some examples, the disease is less ad- vanced : portions of the bone are then met with hose texture and consistence are nearly natural, and which are merely some- what enlarged. But in proceeding towards the centre of the disease, the substance of the bone is found softened, and its consist- ence less than that of cartilage, still mani- festly retaining, however, a fibrous texture ; while more deeply, it is converted into a lard-like substance, resembling (says Boyer) that of parts affected with carcinoma. In these tumours, cysts are often found, some- times containing a fetid ichor, — some- times a matter like clear bouillie ; and, in certain cases, a quantity of semi-transpa- rent, tremulous, gelatinous matter is found in the middle of the lard-like substance. Boyer records an instance, in which nearly the whole humerus was changed into a gelatinous mass. (See Lecqns sur les Mai, des Os, T. 1. Chap. 22.) The prognosis of this disease must always be unfavourable ; for. it is equally incurable, and disposed to bring on fatal consequences, whether Boyer’s opinion, concerning its being cancer of the bones, be true or not. This author notices, that, even after ampu- lation, the complaint almost always recurs. (P.591.) The only chance of relief, how- PAR PAR 249 ever, obviously depends upon the possibility and success of the operation. In the Traitt des Mai. Chir. T. 3, p. 594—605, Boyer re- cords two cases of osteosarcoma ; one of the thigh ; the other, of the os innominatum The first patient was saved by amputation. Some further particulars relative to osteo- sarcoma may be found in Boyer, Traile des Maladies Chir , T. 3; Haller's Element. Phy- siol. T. 8, p. 2, pag. 5; S. A. Kulmus, Diss de Exoslosi Sleatomaiode Claviculee ; Gedan. 3732; S. F Hundertmark, Diss. sistens Os- teostealomatis Casum rariorem ; Lips. 1752; 5. G. Hermann, Hiss, de Ost< osteatomate , Lips. 1767: S. C. Plenck , de Osteosarcosi : Tub. 1781 fyc. B. C. Brodie in Pathol, and Surgi- cal Obs. on the Joints, p. 301. OZiENA. (from o?», a stench.) An ulcer situated in the nose, discharging a fetid pu- rulent matter, and sometimes accompanied with caries of the bones. Some authors have Sig-nified by the term, an ill-conditioned ulcer in the antrum. The first meaning is that which mostly prevails. The disease is des- cribed as coming on with a trifling tumefac- tion and redness about the ala nasi, accom- panied with a discharge of mucus, with which the nostril becomes obstructed. The matter gradually assumes the appearance of pus, is most copious in the morning, and is sometimes attended with sneezing, and a little bleeding. The ulceration occasionally extends round the ala nasi to the cheek, but, seldom far from the nose, the ala of which, also, it rarely destroys. The ozaena is often connected with scrofulous and venereal complaints. In the latter cases, portions of the ossa spongiosa often come away. After the complete cure of all venereal complaints, an exfoliating dead piece of bone will often keep up symptoms, similar to those of the ozama, until it is detached. Mr. Pearson remarks, that the ozaena frequently occurs, as a symptom of the chachexia syphyloidea. It may perforate the septum nasi, destroy the ossa spongiosa, and even the ossa nasi. Such mischief is now more frequently the effect of the chachexia syphyloidea, than of lues venerea. The ozaena must not be con- founded with abscesses in the upper jaw- bone. (See Antrum.) The constitutional disease, on which the ozaena generally depends, and which acts as the remote cause, must be relieved, before a cure of the local effect can be expected. The internal medicines, which may be ne- cessary, are preparations of mercury, and antimony ; sarsaparilla, elm bark, Peruvian bark, muriated barytes, and muriate of lime Sea-bathing may also do good, by improving the health. The best external applications are said to be, preparations of copper, zinc, arsenic, mercury, the pul vis sternutatorius, and diluted suphuric acid. ( Pearson's Prin- ciples of Surgery, Chap. 12 F. A. Mayer t Commentatio de Ozaena, Frank. Del. op. 11 .) OYYMURIATIC ACID. Besides the ni- trous and nitric acids, other medicines, con- taining alarge proportion of oxygen, and easy of decomposition, have been recommend- ed to be tried as remedies for the venereal disease ; viz. oxygenated vinegar, oxalic acid, oxygenated muriate of potash, &c. (See Caldwell's Medical Theses. Vol. T p. 111.) But, perhaps, nothing has been put to the test of experiment with greater expectation of success, than the oxygenated muriatic acid. Mr. Cruikshanks made a very early trial of it in syphilitic cases, and, as is al- leged, w ith the utmost benefit.. He also em ployed the nitric acid, and the oxygenated muriate of potash, and found them eligible remedies The latter medicine w r as likewise given by M Alyon in cases of chancre and secondary ulcers, who found the good ef- fects from it, more expeditious, and more certain, than those of any mercurial prepa- ration. (Essai sur les Pr opr Hies Mcdicinales de rOxyaene, fyc. 8 vo. Paris, an 7 me.) On the other hand, as much contrariety of sen- timent respecting the real and permanent ef- ficacy of all these medicines prevails in the numerous reports about them, as in the ac- counts delivered of the effects of the muria- tic and nitric acid; and, therefore, I do not think that the reader, after the copious state- ments given in this book concerning the nitric and nitrous acids, (see these words) would be pleased to hear again a repetition of very similar contradictions, respecting the oxygenated muriatic acid. I may observe, however, that, if oxygen be the principle, on which the efficacy of many antisyphili- tic remedies truly depend, this acid must possess greater virtue than the common mu- riatic acid. From 3 SS. to 3'j- mixed in ^viij. of water, sweetened with syrup, may be taken in divided doses in the course of the day. Oxygenated muriatic acid was strongly- praised by Guyton de Morveau, as a means of disinfecting sick-rooms, and purifying the air of crowded hospitals. P. P ANA RIS, (from zrapn, uear, and cvw|, ihe nail.) See Whitlow. PANNUS. (from •■srsva. lo labour.) When two or three pterygia, of different sizes oc- curred on the same eye, with their points di- rected towards the centre of the cornea, where they met and covered all the surface of this transparent membrane with a dense pellicle, the ancients named the disease, pannus. (Scarpa, Chap. 14.) PaRACEN 1 E'SIS. (from ftrcipctzsvTea), to perforate.) The operation of tapping or making an opening into the abdomen, tho- rax, or bladder, for the purpose of discharg- ing th» fluid confined in these parts in cases of ascites, empyema, bydrothorax, and PARACENTESIS. ' 5*50 retention of urine. Eft*u«ed blood may also require an opening to be made into the chest; and so may confined air in the instance of emphysema. TAPrr'G, OH PARACENTESIS ABDOMINIS. When the swelling extends equally over the whole abdomen, tin* fluid is usually diffu- sed atnongall the viscera, and is only circum- scribed by the boundaries of the peritonae- um. The water is occasionally included in different cysts, w hich are generally formed in one of the ovaries ; and in this ca^e, the tumour which is produced, is not so uniform, the fluctuation is noi so distinct as in the former instanc-, at least this is the case while the disease has not made very great progress. The difference, also, in the con- sistence of the fluid, may render the fluctua- tion more or less difficult of detection. When the water is contained in different cysts, it is frequently thick and gelatinous; but when it is uniformly diffused all over the cavity of the peritonaeum,, it is generally thinner, and even quite limpid. Sometimes a con iderable number of hydatids are found floating in the fluid, discharged in cases of ascites. Whatever may bp the efficacy of digitalis, mercury, diuretics, and other evacuants in ascites, they are rarely of any service in cases of focal and encysted dropsies. When such swellings continue to enlarge, notw ith- standing the adoption of a few measures which wifi presently be suggested, the soon- er the fluid is evacuated the better. It is also well known, that all efforts to produce a radical cure even of dropsies, which ar< not encysted, too frequently fail. I am decidedly of opinion, however, with Dr Fothergill, that physicians u'ould meet with much more success in the treatment of asci- tes, if they were to recommend paracentesis to be done sooner than they generally do. This operation is, for the most part, much too long delayed; and during a long space, the bowels are continually suffering more and more, from the effect of the large quantity of fluid which oppresses them. What ought to render the practice of eaily tapping more entitled to approbation is, that the operation, when done in the situation which will be presently advised, is perfectly free from danger, attended with very little pain, and need not interrupt the further trial of such medicines as the physician may place confidence in. Paracentesis only be- comes a serious measure when the disease has existed for a great length of time, and the patient has been much weakened by it. Indeed there seems much reason to suspect that the operation should be done as soon as the tension of the abdomen, and the fluctuation, leave no doubt concerning the nature of the malady ; especially when the first t rials which have been made of internal remedies, seem to promise no success. Dr. Fothergill has demonstrated by facts the ad- vantages of this method. On the commence- ment of an ascites, this celebrated practi- tioner advises the trial of diuretics and other evacuants* He then adds, that “ if by a reasonable perseverance in this course, no considerable benefit accrues ; if the viscera do not evidently appear to be obstructed, and unfit for the purposes of life; if the complaints have not been brought on by a long habitual train of intemperance, and from which there seems little hope of re- claiming the patient ; if the strength and time of life are not altogether against us ; I desist from medicine, except of the cordial 'kind : and let the disease proceed til! the operation becomessafely practicable. When this isdone by the moderate use of the warm diuretics, chalybeates, and biiters,also the preparations of squills, in doses below that point at which the stomach would be affected, I endeavour to prevent (he abdomen from filling again.” (Med. Obs. and Inq. Vol. 4, p. 112.) The same author remarks, with regard to encyst- ed dropsies, that tapping sometimes effects a radical cure. The operation should not only be per- formed in as early a stage of the disease as is compatible with the safety of the parts within the abdomen, it should also he repeat- ed as soon as the quantity of fluid accumu- lated again is sufficient to make the puncture practicable without danger. Desault used to tap dropsical patients once a week, and in many ca^es, after he had performed the operation two or three times, the disease was stopped. The great number of times that the ope- ration has been repeated in some individu- als is surprising; for in tance, twenty nine times (Schmucker, J¥ahrnehmungen,2 B. p 102;) fort\-<>ne times (Med. Communica- tions, , Vol. 2;) fifty-two times (Schmucker, Vol..cit. p. 187;) sixtv-five times (Mead ;) one hundred times (Callisen, Syst. Chir. Ho- diernal Vol. 2, p. 55;) one hundred and fifty-five times (Phil. Trans. Vol. 69 ;) and if it be possible to credit Bezard, even six hundred and sixty-five times upon one wo- man in the course of thirteen years. When the patient died, the peritoneum was found to he three lines in thickness. The omen- tum, mesentery, and even the liver, gall- bladder, spleen, pancreas, kidneys, and blad- der, had almost disappeared, a scirrhous mass containing pus occupying their place towards the right side. (See Bulletin de la Socidtd- Medicate d' Emulation, No. 12, Dec.1815.) Whenever a considerable quantity of fluid is suddenly let out of the abdomen by tap- ping, the quick removal of t he pressure of the water oft* the large blood-vessels and viscera, may produce swooning, convulsions, and even sudden death- These consequen- ces led the ancients to consider paracentesis as a very dangerous operation, and when they ventured to perform it, they only let out the w'ater gradually , and at intervals Dr. Mead, after considering what might occasion the bad symptoms resulting from too su den an evacuation of a large quanti- ty of fluid from the abdomen, was led to try what effect external pressure would have in preventing such consequences. This practi*- PARACENTESIS. 351 tioner thought that in this way be might keep up the same degree of pressure which the fluid made on the viscera. The success at- tending some trials of this plan, fully justi- fied the opinion Dr Mead had conceived ; for when the compression is carefully made, the whole of the water co tained in the b- domen of a dropsical palidnt, may be safely discharged as quickly as the surgeon chooses. For this purpose, however, the w hole abdo- men must be equally compres-ed, the pres- sure increased in proportion as the evacua- tion takes place, and kept up in the same degree for several days alterward. In St. Bartholomew’s Hospital, while the water is flowing out, the necessary degree ot pressure is usually made wit a sheet, which is put round the abdomen. Two assistants, who hold the ends of the sheet, gradually tighten it, in proportion as the fluid is discharged. Immediately after the operation, some folded flannel sprinkled w ith spirit of wine, is laid over the whole anterior part of the belly, and covered with a broad linen roller, applied with due tightness round the body. Dr. Monro invented a particular kind of belt for the purpose ; but though it may be well adapted to the object in view, it is, perhaps, unnecessary, as the above method seems to answer every end. Tiie instrument used for tapping the abdo- men, is called a trocar. (See Trocar.) Of this instrument there are -everal varie- ties; but Richter and many other experien- ced surgeons, give a decided preference to the common trocar. Most ofth- modern al- terations which have been made in the construction of trocars, have only tended, says Richter, to render the employment of these instruments more difficult. There is no reason for the ordinary objection, t hat the corjiiion trocar cannot be introduced without considerable force. If the part into which it is about to be passed, be made tense, very little force will be necessary, especially if care be taken to rotate the in- strument gently, as well as push it forward. Hence all the invention- which have origi- nated from this supposed imperfection, are represented by Richter to be entirely useless. He condemns the trocar with a double-edged point, as a bad instrument. The proposal of Mr. Cline to make a puncture w'ith a lancet first, and then ! o introduce into Hie opening a blunt-pointed trocar, is alleged to be su- perfluous. Nay — these innovations are de- clared to be worse ihan useless. A cutting instrument is liable to injure blood-vessels, and bring on a weakening degree of hemor- rhage ; and it is said, that the wound thus made does not heal so readily as that made with a common trocar. That sharp-edged instruments are attended with the inconve nienceof being apt to wound enlarged veins, and produce an unpleasant degree of hemor- rhage, is a truth of w hich I have myself met with a convincing example. A female who had a strong aversion to being tapped w ith a trocar, prevailed upon me to make tiie open- ing wish a lancet. The puncture was made in the linea alba, about three inches below the navel. A stream of dark-coloured ve- nous blood continued to run from the wound, the whole time the water was flowing out of the cannula, and did not cease until a com press was applied. The quantity of blood lost could not be less than a pint, or a pint and a half. In many rases the loss of «o much blood would prove fatal to dropsical patients, and is what one must alway s feel anxious to avoid. The most convenient position for the ope - ration, is certainly when the patient is sitting in an arm-chair. However, weakness and other circumstances frequently make it ne- cessary to operate on the patient as he lies in bed. Until of late, the place in which surgeons used to puncture the abdomen, In cases of ascites, was the centre of a line drawn from the navel to the anterior superior spi nous process of the ilium, and on the left side, which was preferred in consequence of tiie liver not being theie. The place for the puncture was usually marked with ink, and was supposed to be always situated just over a part of the linea semilunaris, w here In e is n< fleshy substance, nor any large blood- vessel, exposed to injury. This calculation, however, u as made w ithout considering that, in dropsy, the parietes ol the abdomen do not yield equaily in every situation. On the contrary, it is known, that the front is always more distended than the lateral parts, and that the recti muscles, in particular, are sometimes very much widened. In conse- quence of these alterations induced by the disease, no dependence can be put on any measurement, made with the view ot ascer- taining the piecise situation of tiie linea semilunaris. The surgeon who trusts to his being aide to introduce the trocar exactly in this place, from any calculation of the above kind, will frequently wound a great thickness of muscle, instead ol a part where the abdo ininal parietes are thinne-t. But a still stronger objection is to be urged against the practice of attempting t-o tap in the linea semilunaris. Men v\ell acquainted with anatomy, have frequently been deceived in their reckoning, and instead of hitting the intended line with their trocars, they have introduced these instruments through the rectu- muscle, and wounded the epigastric artery. Patients have died from this error, with large extravasations of blood in the cavity of the peritonaeum. n a dropsical person, who has been tapped, it is to be ob- served 'also, that an effusion td biood in the abdomen will of course more readily take place, in consequence of the parts not being in the same close, compact state, in which they are in the healthy condition. Let every prudent practitioner, therefore, henceforth abandon the plan of tapping in the linea semilunaris, and he may the more easily make up his mind to do so, as there is another place where the operation may be done with the utmost facility and safety. The iitiea alba is iro vv commonly preferred by the best surgeons ; because, here no muscular fibres need be xvounded. the place PARACENTESIS. B&2 can be hit with certainty, and no large blood-vessel can be injured. About the middle point, between the navel and pubes, is as good a situation for making the punc- ture as can possibly be chosen. The sur- geon should introduce the trocar in a steady, firm manner, never in an incautious, sud den way, lest parts contained in the perito- naeum should be rashly wounded. For the same reason, immediately the point of the trocar has entered the abdomen, a thing always known at once by the sudden ces- sation of resistance to its passing inward, it should be introduced no further, and its office of making a passage for the cannula is already accomplished. The surgeon, con- sequently, is now to take hold of the cannula with the thumb and index finger of his left hand, and gently insinuate it further into the cavity of the peritonaeum, while with his right hand he is to withdraw the stilette. The fluid now gushes out, and regularly as it escapes, the sheet which is round the pa- tient’s body is to be tightened. All the wa- ter having been evacuated, a piece of flan- nel and a roller are to be immediately ap- plied, as above explained, a piece of lint and soap-plaster having been previously applied to the wound. It is not uncommon for the water suddenly to stop, long before the full quantity is dis- charged. Sometimes this happens from a piece of intestine, or omentum, obstructing the cannula. This kind of stoppage may he removed by just introducing a probe or di- rector, and holding the portion of bowel back. When the w ater is very viscid, the only thing we can do is to introduce a large trocar, if doing so should premise to facili- tate the evacuation. Also, when hydatids obstruct the cannula, a larger instrument might allow them to escape. In encysted dropsies, the practitioner, of course, can only let the fluid out of those cavities which he can safely puncture. When a dropsy of the ovary is very large, it also admits of being tapped in the linea alba; but, in this particular case, it is gene- rally best to make the puncture where the swelling is most prominent. In this disease, the ovary is either converted into one large cavity, filled with fluid or else it contains several distinct cells. The contents are sometimes exceedingly viscid. In the early stages of the case, the tumour is situated towards one side of the abdomen, and seems to ascend out of the pelvis. This kind of progress at once distinguishes the disease from a common ascites, which is attended, from the first, with an equal, gradual, uni- versal swelling of the abdomen. The cyst of the ovary, when it has attained a large size, generally adheres, in different places, to the inner surface of the peritonaeum, and, in this state, the whole abdomeu often seems uniformly swollen, in consequence of the immense magnitude of the disease. (See G. D. Mots, (le Structure ! , Usu, el M or bis Ora- riorum, 4lo Jeiur', 178S.) The impairment of the health, arising from the pressure of the viscera, and interruption tbmr func- tions, and the great difficulty of breathing' produced by the pressure on the diaphragm, make it necessary to let out the fluid, and paracentesis must be done in the way alrea- dy related. The disease is often attended with an almost total stoppage of the secre- tion of urine. Sometimes the urine is duly secreted, but a retention occurs, so that the use of the catheter becomes indispensable. Tapping, however, can only be regarded as a palliative measure ; the water collects again, the same grievances recur, and the operation must be repeated. While an ova- rial dropsy is recent, aud even after it has been tapped, some attempts may be made to effect a radical cure. Blistering the sur- face of the abdomen, keeping up a discharge with the savine cerate, and applying a tight roller, have been known to do good. In France, the celebrated Le Dran laid open the cysts of ovarial dropsies. His patients did not die of the consequent inflammation, and the dropsy, indeed, was cured ; but there remained either a sarcomatous en- largement of the ovary, which continued to increase till death, or else incurable fistula;, leading into the cyst, were the consequen- ces. 'J£he large size of a wound necessary for this purpose, the danger of inducing in- flammation in so extensive a surface as the cyst of a large ovarial dropsy, and the events of Le Dran s cases, are circumstances, on the whole, which ought to keep the prac- tice from ever being revived. A still more absurd plan has been attempt- ed, viz. to cure the disease by injections, like hydroceles. I formerly saw' tw r o cases in which port wine and water were inject- ed, by the late Mr. Ramsden of St. Bartho- lomew’s Hospital; one patient died very soon afterward of the inflammation, and the other perished more lingeringly from the same cause. Setons have been tried with- out success. Sometimes, though very seldom, the ope- ration of paracentesis is necessary for giving vent to collections of air in the abdomen Air, when confined in this manner, is gene- rally contained in the bowels, which it in- flates to an enormous size. Instances, how- ever, are related of quantities of air being confined between the peritonaeum and intes- tines : but, in some of these cases, it is said that the air yvas known to have escaped through a small hole in some part of the in- testinal canal, and it is probable, that all the other examples were of the same kind. This disease is named tympanites , and may ren- der making an opening into the abdomen necessary. Notwithstanding authors gene- rally recommend a small trocar for the pur- pose, there can be no doubt that dividing the skin, and making a cautious puncture with a lancet through the linea alba and peritonaeum, would be a preferable mode of proceeding. The abdomen must also be compressed with a sheet while the air is escaping, and afterward with a roller, just as if the case were an ascites, liven when the air is contained in the bowels, it it should enbrutoMs in qmudijv, occasion urgent FAR PAR o63 symptoms, anti cannot be got rid of in other ways, authors recommend paracentesis. PARACENTESIS OF THE THORAX The necessity for this operation is indica- ted when the heart or lungs are oppressed by any kind of fluid confined -in the cavity of the chest. Every body knows that the free and uninterrupted performance of the functions of these organs is essential to the support of life. When the action of these viscera is disturbed by the lodgment of a col- lection of any kind of fluid in the thorax, no internal medicines can be much depended upon for procuring relief. The only means from which benefit can be rationally ex- pected, is letting out the fluid by making an opening in the parietes of the chest. The nature of the effused fluid can make no difference in regard to the propriety of discharging it in this manner; and, though some authors have only treated of this ope- ration as applicable to cases of hydrops pec- toris and empyema, it may also be of the greatest service when air is confined in the chest, (see Emphysema ) or blood extravasa- ted there, (see Woundsof the Thorax) so as to make dangerous pressure on the lungs and diaphragm. In this place I shall content myself with describing the best method of performing paracentesis thoracis, referring the reader to the articles just mentioned for information concerning the particular symptoms and circumstances which may render the opera- tion proper, and the rest of the surgical treatment peculiar to each affection. The safest and most convenient situation for making an opening into the chest, is be- tween the sixth and seventh true ribs, on either side, as circumstances may ^render necessary. The surgeon should only recol- lect, that the two cavities of the pleura are completely distinct from each other, and have no communication whatsoever, so that, if fluid were contained on the left side of the thorax, making an opening into the right cavity would not serve for discharging the accumulated matter. The practitioner should also remember, that, when there is a fluid on both sides of the chest, paracente- sis must never be done for the relief of the two collections at the same time; because there is great reason to believe that, as the lungs on one side usually collapse, when there is a free communication between the air and inside of the thorax, they would do so on both sides, were an opening made at the same time into each bag of the pleura. It is hardly necessary to remark, that, in this condition, the patient could not breathe, and would die suffocated. The operation consists in making an incision, about two inches long, through the integuments which cover the space between the sixth and seventh true ribs, just where the indigita- tions of the serratus major anticus muscle meet those of the externus obliquus. Here it is unnecessary to divide any muscular fibres, except those of the intercostal mus- Voi. II 4.5 cles, and, by putting the patient in a proper posture, the opening that is to be made will be depending enough for any purpose what- soever. The surgeon, avoiding the lower edge of the upper rib, where the intercostal artery lies, is then cautiously to divide the layers of the intercostal muscles, till he brings the pleura into view; when this membrane is to be very carefully ided with a lancet. The instrument should never be introduced in the least deeply, 1 . e lungs should be injured. The size of the opening in the pleura should never be larger than necessary. The discharge of blood and matter will of course require a freer aperture than that of air or water. If requi- site, a cannula may be introduced into the wound for the purpose of facilitating the evacuation of the fluid, and it may even in some cases be proper to let this instrument remain in the part, in order to let the w r ater or pus escape, as often as another accumu- lation takes place. It is obvious, however, that a cannula for this object should only be just long enough to enter the cavity of the pleura, and should have a broad rim to 1 keep it from slipping into the chest. A piece of sticking-plaster would easily fix the can- nula, which might be stopped up with a cork, or any other convenient thing, or left open, according as the circumstances of the case, and the judgment of the surgeon should direct. Paracentesis of the abdomen, and that of the thorax, are described in all treatises on the operations and systems of surgery. The works of Sharp, Le Dran, Bertrandi, Callisen, Rich- ter, Sabatier, Larrey , and Boyer , are particu- larly deserving attention. A case, in which eleven pints of a fluid, resembling whey, were discharged from the chest by paracentesis, and the patient recovered, is detailed by Dr. Archer in the Trans, of the King's and Queen's Col- leges of Physicians in Ireland, Vol. 1 , art. 1. See also JY. Friedreich, Vorzuge des Bauch- stichesin der Bauchwassersucht, 12 mo. Wurzb. 1816, 1817. For an account of the paracentesis of the bladder, refer to Bladder, Puncture of. Con- sult also Emphysema, Empyema, and Wounds of the Thorax. PARAPHYMO'SIS, or Paraphimosis. (from mget, back, and cpifxo to bridle.) This signifies the case in which the prepuce is drawn quite behind the glans penis, and cannot be brought forward again. See Phymosis, with which it will be considered. PAKONY'CHIA. (from near, and ovv$j, the nail.) An abscess at the end of the finger, near the nail. See Whitlow. PAROTID DUCT. Every one acquaint- ed w ith anatomy is aware, that behind the jaw 7 , on each side, there is situated a large conglomerate gland, being the principal one of such as are destined to secrete the saliva, with which the cavity of the mouth, and the food which we swallow, are continually moistened. The parotid duct crosses the cheek, being situated about one-third from the zygofoa, and two-thirds from the basis' of the jaw. After passing over the ma&setev PAH PAR 354 muscle, it pierces the buccinator, and ter-, mrnates in the mouth by a considerable ori- fice opposite the space, between the second and third bicuspid grinders of the upper jaw. As soon as it has passed the masseter, it dives deeply into the fat of the cheek, and, as M. Louis observes, makes an angle be- fore it opens into the mouth. ( M6m . de Acad. de Chir. T. 3, p. 457 ) From the situation of the parotid duct it is liable to be wounded, and this has even been done by the surgeon’s lancet, through ignorance. (See Monro’s Works, p. 520.) In cases of this kind, the continual escape of saliva may prevent the wound from heal- ing, and, what is called a salivary fistula would be the perpetual consequence, if no steps were taken to afford relief. The pa- rotid duct has sometimes been ruptured by blows. ( CEuvres Chir. de Desault, T. 2, p. 221.) Cases also occur, in which the face becomes considerably swollen, in conse- quence of the saliva insinuating itself into the cellular substance, just as the air does In emphysema. Respecting the last circum- stance, I shall only just mention, that mis- chief of this kind must always be prevented lrom becoming very extensive, by making a depending opening for the ready escape of the fluid. With regard to the treatment of salivary fistulae, if the division of the parotid duct is recent, the sides of the wound should be ■brought into contact, and a steady pressure maintained on that part of the cheek, by means of suitable compresses and a roller. In this manner, a salivary fistula may often be prevented altogether : either the divided ends of the duct reunite, and the spittle re- sumes its original course into the mouth ; or, what is more probable, the wound in the face heals at every part, with the exception of a small fistulous track, which serves as a continuation of the duct into the inside of the mouth. The latter kind of cure, how- ever, can only take place when the wound extends quite through the cheek ; but the chance of the two portions of the duct uni- ting, and becoming continuous’again, should always be taken in recent cases. When a salivary fistula is actually form- ed, a seton, introduced from the external fistulous orifice into the mouth, is a method which seems to have, with justice, the great- est share of approbation. The celebrated Monro adopted this plan with success ; he k^ept in the selon till the channel, which it had formed, had become fistulous, after which it was withdrawn, the external orifice being touched with the argentum nitratum, healed up, and the saliva in future flowed through the artificial fistulous channel into the mouth. Desault used to practise the seton as fol- lows : — He introduced two fingers of his left hand into the patient’s mouth, and pla- cing them between the teeth and the cheek, opposite the fistula, thus kept the integu- ments tense, and the gums from being in- jured. He then introduced a small hydro- cele trocar, with its cannula, just before the opening of the posterior part of the doct, and pushed it through the cheek, in a direc tion a little inclined forward. An assistant now took hold of the cannula, while Desault withdrew the perforator, and passed through the tube a bit of thread into the cavity of the mouth. The cannula was next taken out, and a seton, which was then fastened to the end of the thread in the mouth, was drawn from w r ithin outward ; but not so far as to come between the edges of the exter- nal opening, where the thread alone lodged, and this was fastened with sticking-plaster to the outside of the cheek. The outer wound was dressed with lint and compres- ses. Desault used to change the seton daily, introducing regularly rather a larger one, and taking especial care not to bring it be- tween the edges of the wound, which was afterward covered with sticking plaster. He enjoined the patient not to move the jaw much, and only allowed him, for some time, liquid food. In about six weeks he used to omit the seton, leaving in the thread, however, for a little while longer. This being taken way, he used to finish the cure by touching the little aperture remaining, with caustic. The making of an artificial passage is one of the most ancient plans of curing salivary fistulae. Every author has had his particu- lar method of doing it, and numerous va- riations are to be met with, either in the instrument employed for piercing the cheek, or in the substance intended for maintaining the opening. For the first step of the ope- ration, surgeons sometimes used the actual cautery, as Saviard furnishes us an instance of ; sometimes an awl, as Monro did ; some- times a common knife, or lancet ; some- times a straight needle, which drew in the thread after it ; but Desault’s trocar gene- rally merits the preference, because the cannula, by remaining in the wound after the perforator is withdrawn, allows the thread to be introduced, which in every other way is either difficult to accomplish, or requires the use of several instruments. For the second step of the operation, viz. keeping the opening distended, cannula; were employed by Duphenix, w r ho used to make a suture over them ; a plan objection - able, inasmuch as it w r as attended with the inconvenience of a solid body left in the parts, and also that of the instrument being apt to slip into the mouth. The setoti, therefore, ought to be preferred, and there can be no doubt that Desault’s method is better than the one followed by Monro (See on this subject, Monro's Works; CEu- vres Chir. de Desault, par Bichat, T. 2, p 221. Also M&m. de l' Acad, de Chir. T. S. J. B. Siebold, Diss. sistens Historiam Syste- matis Salivalis physiologice et pathologice con siderati,fol. Jencc, 1797.) PAROTID GLAND, EXTIRPATION OF. (See Tumours.) PARU'LIS. (from r^ar, and the gum.) An inflammation, boll, or ab sues? in the gums- PENIS. PENIS, AMPUTATION OF. No part of The penis should ever be amputated, on ac- count of a mortification, because the dead portion will be naturally thrown off, and the ulcer heal without the least occasion for putting the patient to any pain from the employment of the knife. Some cancerous and fungous diseases, are the cases in which it is often really proper and necessary to amputate more or less of this organ. However, before a surgeon ventures to do the operation, he ought to be certain that it is the substance of the penis which is incurably diseased ; for, as that judicious surgeon Callisen remarks, tumours, excres- cences, ulcers, and gangrenous mischief, of the prepuce, sometimes present appearances which may lead an inexperienced practi- tioner to fancy the whole thickness of the part affected with irremediable disorder, while the glans is actually in a sound state. Hence, whenever the least doubt exists, it is better to remove first the prepuce and skin, in order that the true condition of the glans may be detected. ( Callisen , Systema Chirurgia Hodiemce, pars posterior, p. 420, Hafnicc , 1800.) The old surgeons, fearful of hemorrhage, used sometimes to extirpate a part of the penis, by tying ligatures round it with suffi- cient tightness to make it mortify, and slough off. Thus Ruysch once performed the operation. (See Obsv. 30) The plan, how- ever, is exceedingly painful, and notwith- standing the authority of Heister, has been most properly rejected from modern surgery. The amputation may be done in the fol- lowing manner : — A circular incision is to be made through the skin, abcuit a finger- breadth from the cancerous part. As Calli- sen observes, it is hardly ever requisite to draw' the skin back before it is cut ; be- cause after the corpora cavernosa are divi- ded, they retract so considerably, that there is always a sufficiency of the integuments. (Syst. Chir. Hodiemce, pars posterior, p. 421.) As soon, therefore, as the circular incision through the skin has been made, the cor- pora cavernosa and urethra are to be cut through, by one stroke of the knife, on a level with the cut edges of the integuments. Sabatier even advises us to draw the skin towards the glans penis, before we employ the knife, so convinced is he of the inutility of saving any of it, and of the inconveni- ences which may result from its lying over and obstructing the orifice of the urethra. His mode of operating is also particularly simple, as he cuts through the integuments and penis together by one stroke of the knife, without making any preliminary cir- cular division of the skin. ( Mddecine Op6- ratoire , T. 3, p. 305, Edit. 2.) The bleeding arteries are now to be im- mediately tied : the chief are, one on the dorsum of the penis, and *one in each cor- pus cavernosum. When a general oozing from the wound still continues, some re- commend ( IVhile, Hey, §'c.) applying sponge to its surface ; others ( Latta ) finely scraped agaric, with a small proportion of pounded 35o white sugar, or gum arabic. Perhaps, how- ever, finely scraped lint, supported with compresses, would be quite as effectual as any styptics, and certainly the latter appli- cations should be avoided, if possible, be- cause stimulating, and productive of pain and inflammation. A surer and preferable method of stopping the oozing of blood, and at the same time of healing the wound, might be to bring the skin forward over the end of the stump, with two strips of sticking plaster, after introducing a flexible gum ca- theter into the continuation of the urethra, so as to keep its orifice unobstructed, and the urine from coming into contact with the wound. There can be little doubt that the gum catheter would be better than a silver one, or any metallic cannula, com- monly advised for the above purposes, be- cause it lies in the passage with less irrita- tion. It is but justice to Callisen to state, that he seems to be one of the few good surgical writers, who have particularly re- commended in these cases the elastic gum catheter, in preference to that made of sil- ver. (Op. cit. p. 421.) In one case, in which Mr. Hey operated, he made a longi- tudinal division of the integuments, at the inferior part of the penis, so as to make them cover its extremity without puckering, or lying over the orifice of the urethra. The corpora cavernosa, however, do not readily granulate, and unite to the skin by the first intention. (Hey, p. 452.) After the first dressings are removed, the part should be dressed with the unguentum spermatis ceti, or any mild unirritating salve. In consequence of the introduction of a cannula being neglected, Le Dran mentions his having seen the orifice of the urethra become closed a few hours after the opera- tion, so that the patient could not make water. The orifice of the passage could not be discovered without great difficulty. A lancet being introduced at the point, against which the urine seemed to be forced, a quantity of it gushed out, and as a cannula was not at hand, a sound was introduced till one could be procured. (Traitd des Oper. de Chirurgie.) Pearson, in his Practical Observations on Cancerous Complaints , has treated of this operation : he particularly advises the skin not to be drawn back, because, when saved in this manner, it impedes the free exit of the urine- He likewise disapproves of introducing cannula), as creative of pain, and spasms of the urethra, and unnecessary, since the stream of urine will always preserve the urethra in a permeable state. (P. 103.) When the penis is amputated near the pubes, the remainder shrinks under that bone and within the integuments so far, that it is difficult to tie the arteries. 1 n order to obviate this inconvenience, Schreger recommends the skin to be drawn forwards, and fixed with a band ; then to make an incision only deep enough to divide the dorsal arteries, which are to be tied, before the knife is used again. The incision is then to be con- tinued perpendicularly, till the two arteries 35.6 PEN PH a of the eo: pora cavernosa are cut. These are now to be tied. Then the corpus spongiosum and its two arteries are to be cut through, which last are to be secured. Lastly, the rest of the skin of the penis is to be divided. In this way Schreger amputated a diseased penis, of which ofily a part, about an inch in length, was sound. . (Sharp, Le Dran, Eertrandi , and Sabatier's books on the operations , may be consulted. Also, I' Encyclopedic Melhodique ; Par lie Chir. Art. Verge. Hey' s Practical Observa- tions in Surgery, p. 445. Pearson on Can- cerous Complaints, p. 103, fyc. Warner's Cases in Surgery, p. 278, Edit. 4. E. C. Biener, De Exlirpalione Penis per Ligatu- ram,4to. Lips. 1S16. J. H- Thaut, Diss. de Virgce Virilis Statu sano et morb. ejusdem im- primis ampulalione. B. G. Schreger’s Chir. Fersuche; JYeue Melhode den Penis zu Am- putvren , B. l,p. 242, 8 vo. JVurnberg, 1801.) PENIS, CANCER OF. A wart, or a tubercle, on the prepuce, the fraenum,or the glans penis, is generally the first symptom, and it often remains in a quiet state for ma- ny years. When irritated, however, it be- comes painful, and enlarges, sometimes enormously in a very short time. At the same time ulceration, and a discharge of sa- nious fetid matter, take place. The disease sometimes also occasions in the urethra fis- tulous openings, out of which the urine es- capes, and the lymphatic glands in the groin may become affected as the disease advances. Mr. Pearson says, that “ cancerous excres- cences have a broad base, often more exten- sive than their superficies; they seem to germinate deeply from within, or rather to be a continuation of the substance of the part ; and. in their progressive state, the contiguous surface has a morbid appear- ance.” What Mr. P. considers as a venereal wart, has a basis smaller than its surface ; its roots have rather a superficial attach, ment, and the contiguous parts have a na- tural appearance (p. 97.) Such are this gentleman’s marks of discrimination. We might question, however, whether Mi*. Pearson, notwithstanding his great opportu- nities, ever saw a really venereal wart. For many years past 1 have never seen any ex- crescences of this kind in St. Bartholomew’s hospital, which truly required mercury for their cure, or which, when cured without it, were followed by any inconvenience. If my memory does not fail me, Mr. Aberne- thy also disbelieves in the doctrine of vene- real warts. Foul, spreading, sloughy ulcers of the penis, should be discriminated from cancer. It is worthy of attention that almost all the cases of cancer of the penis recorded by Mr. Hey were attended with a congenital phymosis. The same complication also ex- isted in another example, in which Boyer performed amputation of the penis in la Charitfc, on account of a cancerous affection of the part. In the only two opportunities of doing this operation, which M Roux has had, the cases were likewise accompanied with a natural phyrnosi's. Hence, this au- thor considers such a state of the prepuce as particularly conducive to cancer of the penis, and earnestly enjoins surgeons to re- commeud their patients to have the first inconvenience rectified, so that no risk of the other more serious affection may be en- countered. (See Parallele de la Chirurgie Angloise , fyc. p. 306, 307.) In two out of three cases which were reported to be can- cerous, and for which amputation was done under my notice, it did not appear that any degree of phymosis existed. (See Pearson on Cancerous Complaints. Hey's Practical Observations in Surgery . Roux, Voyage fait en Aagleterre en 1814, ou Parallele. de la Chir. Angloise, tyc. p. 306.) PERINEUM, FISTULA OF. (See Fistulce in Perinoeo.) PE'RNIO. (from , to soften.) The intention of pessaries among the old prac- titioners, was to keep medicinal substances applied within the pudenda. They are now never made use of, except lor preventing a prolapsus of the uterus or vagina, or for keeping up a very uncommon kind of rup- ture, explained in the article Hernia. PIIAGEDvE'NA. (from u.yce, to eat.) An ulcer which spreads, and as it were eats away the flesh. Hence the epithet, phagedenic, so common among surgeons. For an account of the phagedoena, gangree- nosa, see Hospital Gangrene. PHARYNGOTOMY. (from , to inflame.) An inflammation. A flushing. PHRENI'TIS. (from the diaphragm, supposed by the ancients to be the seat of the mind.) An inflammation of the brain. Phrensy. Inflammation of the brain is a frequent consequence of injuries of the head. The symptoms are an increased and disordered state of the sensibility of the whole nervous system ; the retina cannot bear (lie usual stimulus of light ; the pupils are contracted ; the pulse is frequent and small ; the eyes are red and turgid, arid the iris sometimes actually inflamed, (E ardrop, Essays on the Morbid Anal, of the Eye, Vol. 2,1 the coun- tenance is flushed, and the patient is rest W-IYMOSJS ie.'?, mutters incoherently, and grows wild and delirious. Phrenitis is treated on the antiphlogistic plan. Copious bleedings and other evacua- tions, are highly proper. Some of the blood should be taken from the temporal arteries. The skin ought to be kept moist with anti- monials, and a counter-irritation should be excited on the scalp by blisters. PHY'MA. (from , to grow.) Tuber- cles comprehend eight genera, and we learn from Dr. Bateman, that, under the ge- nus phyma, the late Dr. Willan intended to comprise the terminthus, the epinyctis, the furunculus, and the carbuncle. (See Bate- man's Synopsis of Cutaneous Diseases, p. 270, Edit. 3.) According to Pott, this term was formerly applied to an inflammation near the anus. See Anus , Abscesses of . PHYMOSIS, or rather Phimosis, (from Vi/uoc, a muzzle.) A case in which the pre- puce cannot be drawn back, so as to unco- ver the glans penis. It is of two kinds, viz. accidental , and natural or congenital. Both the accidental phymosis, and para- phymosis, according to Mr. Hunter, arise from a thickening of the cellular membrane of the prepuce, in consequence of an irrita- tion capable of producing considerable and diffused inflammation. A chancre is a fre quent cause ; but a mere inflammation and discharge from the glans and prepuce, and also a gonorrhoea, may bring on these affec- tions. The inflammation often runs high, and is frequently of the erysipelatous kind. The cellular membrane being loose, the tu- mefaction becomes considerable, and the end of the prepuce being a depending part, the serum often lodges in it, and makes it oedematous. A congenital contraction of the aperture of the prepuce is very common, and persons so affected have a natural and constant phymosis. Such a state of parts (says Mr. Hunter) is often attended with chancres, and it produces very great incon- veniences during the treatment. When there is considerable diffused inflammation, a diseased phymosis similar to the natural one, unavoidably follows; and whether diseased or natural, it may produce a para- phymosis, simply by the prepuce being brought back upon the penis. This tight part, then acting as a ligature round the body of the penis, behind the glans, retards the circulation beyond the constriction, so as to produce an oedematous inflammation on the inverted part of the prepuce. When the prepuce is very long, phymosis may also arise from the swelling of the glans penis, produced by sores on the latter part, or the irritation of a severe gonor- rhoea. ( Travers in Surgical Essays, Part 1, p. 132.) My own observations lead me to consider an irritation and swelling of the prepuce itself as by far the most common causes of the accidental phymosis. In some children, the natural or congenital phymosis is so considerable, that the urine cannot pass with ease ; but the aperture of the prepuce generally becomes larger as they grow older, and the bad consequences which the phymosis might have occasioned in disease, are thus avoided. In certain individuals, especially old men, the prepuce sometimes contracts without any visible cause whatever, and becomes so narrow as to hinder the water from getting out, even after it has got free of the urethra, and consequently, the whole cavity of the prepuce becomes filled with urine, attended with great pain. In phymosis, when the prepuce swells and thickens, more and more of the skin of the penis is drawn forwards over the glans, and the latter part becomes at the same time pushed backward by the ^welling against its end. From such a cause Mr. Hunter has seen the prepuce projecting more than three inches beyond the glans, with its aperture much diminished. Mr. Hunter also notices, that the prepuce often becomes, in some degree, inverted, by the inner skin yielding more than the outer, and the part seems to have a kind of neck where the outer skin naturally termi- nates. From the tightness and distention of the parts, the prepuce now cannot be drawn more back, so as to expose any sores, which may be situated under it. This state is frequently productive of bad consequen- ces, especially when there are chancres be- hind the glans ; for, the glans being between the orifice of the prepuce and the sores, the matter sometimes cannot get a passage for- ward, between the glans and prepuce, and, consequently, it accumulates behind the co- rona glandis, so as to form a kind of abscess, which produces ulceration on the inside of the prepuce. This abscess bursts externally, and the glans, often protruding through the opening, the whole prepuce becomes thrown towards the opposite side, and the penis seems to have two terminations. On the other hand, (says Mr. Hunter) if the pre- puce is loose and wide, and is either accus- tomed to be kept back in its sound state, or is pulled back to admit of the chancres be- ing dressed, and is allowed to remain in this situation, till the above tumefaction takes place, the case is then named a para- phymosis. Also, when the prepuce is pulled forcibly back, after it is swelled, it is then brought from the state of a phymosis to that of a paraphymosis. The latter case is often attended with worse symptoms than the former, especially when it has first been a phymosis. According to Mr. Hunter, the reason of this is, that the aperture of the prepuce is naturally less elastic than any other part of it ; therefore, when the pre- puce is pulled back upon the body of the penis, that part grasps it more tightly than any other portion of the skin of Ihe penis, and more so, according to the inflammation . Hence, there are two swellings of the pre- puce, one close to the glands; the other behind the stricture. The constriction is often so great as to interrupt the circulation beyond it. This increases the swelling, adds to the stricture, and often produces a morti- fication of the prepuce itself, by which means the whole diseased part, together with the 356 PHIMOSIS. stricture, is sometimes removed, forming, as Hunter ably expresses himself, a natural cure. In many cases, the skin and pre- puce are not the only parts affected ; adhe- sions, and even mortification may also take place in the glans, corpora cavernosa, &,c. (See Hunter on the Venereal, 221, ^c.) An accidental phymosis should always be prevented if possible, and therefore, says Mr. Hunter, upon the least signs of a thick- ening of the prepuce, which is known by its being retracted with difficulty and pain, the patient should be kept quiet ; if in bed, so much the better, as in a horizontal posi- tion, the end of Jhe penis will not be so de- pending. If confinement in bed cannot be complied with, the end of the penis should be kept up, though this can hardly be done when the patient is walking about. The object of this plan is to keep the extrava- ted fluids from gravitating to the prepuce, which they would hinder from being drawn back again even more than the inflammation itself. When phymosis is recent, and attended with swelling of the glans or prepuce from inflammation, Mr. Travers recommends in- jections of tepid water, or milk and water, beneath the foreskin ; and the immersion of the penis three or four times a day, in a te- pid bath, keeping the end of the penis up- wards ; and the use of leeches ; which I think with him and other writers, (see Did. des Sciences Med. T. 41, p. 334,) should ne- ver be put exactly on the swelled prepuce itself. As the inflammation subsides, injec- tions of weak goulard, or the solution of alum, or liquor calcis and calomel, may be substituted. ( Travers, Surgical Essays, Part l,p.l36.) Instead of warm applications, some practitioners prefer cold : and it is yet an unsettled question which remedies an- swer best. When the inflammation is of longer standing, the swelling compresses the ure- thra, and there is tendency to abscess, ul- ceration of the latter passage, extravasation of urine, land gangrene of the skin, Mr. Travers advises the employment of emol- lient poultices and fomentations (the com- mon practice, I believe,) and the introduc- tion of a small elastic gum-catheter into the bladder. “ This (says he) is not a practice indicated by the degree of stricture, which is seldom considerable enough to require it : but, by the approaching danger of ex- travasation. It should not , therefore, be taken up, unless the cellular membrane of the penis has advanced to suppuration.'' As when there are sores, they cannot be dressed in the common way, injections must frequently be thrown under the prepuce, or the operation for phymosis performed. Mr. Hunter advises mercurial injections ; either crude mercury, rubbed down with a thick solution of gum-arabic ; or calomel with the same, and a proportion of opium ; or else a solution of one grain of the oxymu- riate of mercury in one ounce of water. Mr. Hunter also recommends the applica- tion of emollient poultices, with laudanum in them, and to let the part, previously to the application being made, hang over the steam of hot water, with a little vinegar and spirit of wine in it. When, in a case of phymosis, chancres bleed, Mr. Hunter recommends the oil of turpentine as the best stimulus for making the vessels contract ; but, when the hemor- rhage proceeds from irritation, he recom- mends sedatives. Whatever is used, he says, must be injected under the prepuce. Under such circumstances, it has always been a rule with me to avoid irritating ap- plications, and on this account I have never used turpentine, particularly as any trouble- some bleeding from chancres may always be effectually checked by covering the pe- nis with linen kept well wet with very cold water. When the inflammation has abated, Mr. Hunter advises moving the prepuce oc- casionally, to prevent its becoming adhe- rent to the glans. He says, he has seen the opening of the prepuce so much contract- ed, from the internal ulcers healing and uni- ting, that there was hardly any passage for the water. If the passage in the prepuce, so contracted, be in a direct line with the orifice of the urethra, a bougie must be used. If otherwise, the operation of slit- ting up, or removing part of the prepuce, becomes necessary. When matter is confined under the pre- puce, in the manner above described, Mr. Hunter recommends laying the prepuce open, from the external orifice to the bot- tom, where the matter lies, as in a sinus or fistula. However, Mr. Hunter thinks laying open the prepuce for the :nre purpose of applying dressings unnecessary, as the sores may be washed with injections, by means of a syringe. I happened to serve my apprenticeship at St. Bartholomew’s, at a time when the fa- shion of cutting every phymosis, inflamed or not, was far too common, and I had abundant opportunities of witnessing the ir- reparable gangrenous mischief frequently thus produced. It gives me pleasure, there- fore, to find this villanous practice justly disapproved of by a modern writer. “ It is not adviseable, (says Mr. Travers,) to cut the inflamed prepuce, nor, indeed, any in- flamed part. I lately saw a phymosis indu- ced by a thickened and rigid state of the membrane of the prepuce, during the free use of mercury, constitutionally and locally, for the cure of two sores, each of the size of a split pea, situated one on each side of the anterior fold of the prepuce. It was the opinion of an eminent surgeon, that those sores, wdiicli were thoroughly intract- able, would not heal unless the prepuce was freely divided ; and, impressed with the same idea, after poulticing for some days, I slit it up. The sores immediately healed ; but the wound as quickly assumed the same indolent and intractable character which had belonged to the sores, and was so slow in healing, that it seemed to he only a transfer of the disease from one part to another.” (P. 139.) f have not only PHYMOSIS 359 >vitnessed the same fact, in several cases under the late Mr. Ramsden, and in St. Bartholomew’s Hospital, but have seen mor- tification brought on by the still more rash practice of cutting the prepuce either when the part was in a state of acute inflamma- tion, or there were ulcers within it, when the constitution was in a reduced and very disordered state from the injudicious and immoderate use of mercury. The common operation, for the cure of phymosis, consists in slitting open the pre- puce, nearly its whole length, in the direc- tion of the penis. This plan is certainly the most eligible, when the matter of a chancre cannot escape from under the prepuce ; be- cause circumcision, which many surgeons, since Mr. Hunter’s time, have preferred, would not suffice forgiving vent to the ac- cumulated pus. In many cases of phymo- sis, says Mr. Hunter, an operation is impro- per; for, while the inflammation is very considerable, such a measure might bring on mortification. He acknowledges, how- ever, that there are cases, in which a free- dom given to the parts would prevent the latter event. When matter is confined un- der the prepuce, an opening is indispensa- ble, and, if the patient should object to the common operation, an opening should be made with a lancet directly through the prepuce, or else with a caustic. (See Hun- ter on the Venereal Disease, p. 232, etseq .) When the prepuce is to be slit open, a di- rector is first to be introduced under it, and the division is then to be made with a curved pointed bistoury, from, within upward. Many surgeons object to this operation, because the prepuce continues afterward in a very deformed state ; and they perform circumcision, or amputation of the prepuce, ?n the following manner. The prepuce is first taken hold of with a pair of forceps, •as much of the part being left out, as is judged necessary to be removed. The re- moval is then accomplished by one sweep of the knife, which directed by the blades °/ the forceps, is sure of making the inci- sion in a straight and regular manner. A fine suture is next passed through the edges of the inner and outer portions of the skin of the prepuce so as to keep them together. The anly necessary dressings are lint, and over it an emollient poultice. At the period when I first entered the profession, it was the custom to salivate every patient who happened to have a phy- mosis. How r ever, now that the fact of any irritation about the prepuce and glans penis, even that of common warts, being capable of producing the complaint is well known, such absurd practice has been relinquished, and the cause and condition of the disease are always considered previously to the de- termination for any particular method of treatment. Nay, even when phymosis does arise from chancres, if there be a great deal ot inflammation, the use of mercury may rather do harm than good, and the practitioner should not be precipitate in its administration On this point. I fully coin- cide with Mr. Travers : — Upon many oc- casions (says he) practitioners are too anxious to contend with the scientific cha- racter of the venereal disease, to the neglect of the inflammatory state of the affected parts exhibited duringits height. The abuse of administering mercury for an acute go- norrhoea, and recent sores, accompanied by phymosis, or an approach to that state, is of common occurrence, and it is far from being recognized by the profession, as an estab- lished rule of practice, that its constitutional administration is inadmissible during the existence of active inflammation, in cellular textures.” ( Surgical Essays, Part 1 ,p. 131.) In nine cases out of twelve, in which the experienced Mr. Hey had occasion to am- putate the penis for cancerous disease, the patients were also affected with a natural phymosis. ( Pract . Obs. in Surgery.) Roux has noticed the same thing in three similar examples, and, therefore, as he conceives that phymosis may be conducive to carci- noma of the penis, he thinks that it should always be remedied in time. (Parallble de la Chir. Angloise, p. 306.) TREATMENT OF PARAPHYMOSIS. The removal of the stricture in this case should always be effected, because its con- tinuation is apt to produce a mortification in the parts, between the stricture and the glans. It may be done in two ways ; either by compressing with the fingers all the blood out of the swelled glans so as to ren- der this part sufficiently small to allow the constricting prepuce to be brought forward over it, with the aid of the two fingers ; or by dividing the stricture with a knife. In the last edition of this work, as Mr. Dunn of Scarborough has reminded me, the power of cold applications, in promoting the re- duction of the glans, should have been men- tioned. This method should always be put in practice, before the reduction by com- pression is attempted, as a preliminary measure, wiiich sometimes succeeds of itself, and renders unnecessary any painful handling of the parts. From the great success, which I have seen attend the first mode, I should not conceive the second one so frequently necessary, as Mr. Hunter seems to lay down. This operation is always troublesome to accomplish, because the swelling, on each side of the stricture, covers or closes the tight part, which cannot be got at without difficulty. Mr. Hunter says, the best way is to separate the two swellings, as much as possible, where you mean to cut, so as to expose the constricted part ; then take a crooked-pointed bistoury, pass it under the constriction, and divide it. None of the swollen skin, on each side, should be cut. The prepuce may now be brought forward, unless it be thought more convenient, for the purpose of dressing the chancres, to let it remain in its present situ- ation. (See Hunter on the Venereal Dis- ease, p. 238, 239.) The original disease producing phymosis and parapbymosis, must always be attended /*()0 PIL PIL to, and the employment of mercury must be necessary or unncessary, according to the nature of the affection, of which these are only effects. One of the most interesting writers on Phy - inosis and Paraphymosis is J. L. Petit, Trails (Its Mai. Chir. T. 2 ; many of whose valuable observations are contained in the 2 d vol. of the First Lines of Surgery , 8 vo. 1820. Consult also J. Hunter on the Venereal Disease. Sa- batier, Medecine Op&ratoire, T.S, 8 vo. Paris, 1810. Travers , in Surgical Essays, Part 1, 8 no. Loud. 1818. There is also a valuable chapter on this subject in Richter's Anfangsgr. der Wundarzn. B. 6. PILES. (See Hemorrhoids.) PILULES AMMONIARETI CUPRI — ft. Cupri Ammoniareti gr. xvj. Micee Panis 3)iv. Liquoris Ammon, q. s. M. fiant pilulae xxxii. (Edinb. Disp.) This is said to be the best form of exhibiting copper internally, which mineral some think worthy of trial in cases of gleets. PILULE ARGENTI NITRAT1S. ft. Argenti Nitratis gr. iij. Aquae Distillates gutt. aliquot. Micae Panis q. s. ut fiant pil. xx. The author of the Pharmacopoeia Chirurgica suggests the trial of these pills in obstinate leprous, and other cutaneous affections, and phagedenic, anomalous ulcers, connected with constitutional causes. Two or three may be given twice a day. Dr. Powell gave the’argentum nitratum internally, in a case of hydrophobia, but without any sensible effect. PILULE COLOCYNTIIIDIS CUM HYDR. SUBM. ft. Extracti Colocynth. comp. 3’»j. Hydr. Submur. gr. xii. Saponis 3j. Misce. ut fiant pilulae duodecim. Two of these pills operate as a purgative, and they ace often prescribed in various surgi- cal cases. PILULES CONIL ft. Extracti Conii 3ss. Pulv. Herb. Cicutae q. s. fiant pil. lx. These are the hemlock pills in use at Guy's Hos- pital. Cicuta is occasionally given in scro- fulous, cancerous, and venereal cases. The surgeon should begin with small doses, and increase them gradually, till nausea and headach arise. From one to a greater number of these pills may be given, in this manner, every day. PILULE CUPRI SULPHATtS. ft. Cupri Sulphatis gr. xv. Olibani Extracti Cinchona;, sing. 3'j- Syrup, simpl. q.s. fiant pil. lx. From one to four of these pills may be given in a day, for gleets. ( Pliarm . Chirurg.) PILUL E HYDRARGYRI. Of these, I need only observe here, that the usual dose is ten' grains. (See Mercury.) PILULAE HYDRARGYRI OXYDI RU- BRI. One grain of this preparation in each pill is the dose, which is commonly taken at bedtime. (See Mercury.) PILULE HYDRARGYRI CUM CONIO. ft. Hydrargyri puriiicati drach. j. Arabici gummi pulverisati drach. ij. Extracti Conii drach. j. Herb® Cicutae foliorum,in pulve- rem tritorum, q. s. The quicksilver is to be first reduced by triture with the gum arabic, moistened with a little rain water. The in- spissated juice of hemlock is afterward to her added, and lastly, the powdered leaves in sufficient quantity to make a suitable mas* for pills. These with a slight variation in the proportion of the hemlock, are the pilules mercuriales of Plenck, who directs three or four pills, each of three grains, to be given every night and morning. There are, no doubt, many cases, to which this formula must be very suitable ; as for instance, the enlarged prostate gland, and some forms of bronchocele, &c. For such diseases. Dr. Saunders, in his Formulce Selectee , directs equal parts of pil. hydrarg. andex- tractum conii. ( Pharm . Chir.) PILULE HYDRARG. SUBMUR. ft. Hydrarg. Submur. gr. xij. Conservae Cynos- bati quod satis sit. M. fiant pil. xii. These are the calomel pills in common use. Sur- geons give one, or two of them daily, as al- teratives, in numerous cases. At Guy’s Hos- pital, they add three grains of the pulvis opiatus to each pill, using syrup, instead of the conserve. PILUL/E HYDRARG. SUBMUR. CUM CONIO. ft. Hydrarg. Submur. gr. vj. Ex- tracti Conii 3j. M. fiant pil. xii. One maybe given thrice a day, in scirrhous, cancerous, scrofulous, and some anomalous diseases, resembling venereal diseases. PILULE: HYDRARGYRI SUBMUR. CUM ANTIMONIO TARTARISATO. ft. Hy- drarg. Submur. 3j- Antimon. Tga-t. gr. xv. Opii. Pur. 3ss. Syrupi simpl. q. s. fiant pil Jx. One of these is given twice a day, in St. Thomas’s Hospital, in cases of diseased joints. As the author of the Pharm. Chirurg. adds, they are also of use in herpetic affections, and obstinate ulcers. The union of antimony with quicksilver, according to Dr. G. Fordyce, quickens the specific opera- tion of the latter. pilule: hydrarg. submur. com- posite:. ft. Hydrarg. Subm. Sulph. An- tim. Prajcip. sing. gr. xii. Guaiaci Gummi Resina; gr. xxiv. Saponis q. s. M. fiant pil. xii. Similar to Plummer’s pills: In porrigo, herpetic affections, and many anomalous diseases, they are exceedingly useful. Some diseased enlargements of the breast, and tes- ticle, seem also to be benefited by them. PILULE! OPII. These need ^mly be mentioned among such as are of eminent utility in surgery. pilule: opii composite:, ft. Opii Purif. Camphor®, sing. 3j- Antim. Tart. gr. xv. Syrup. Simpl. q. s. fiant. pil. Ix. Used for alleviating pain, and keeping up a gentle perspiration ; are particularly useful in pre- venting painful erections, in cases of gonor- rhoea, chordee, &c. (See Pharm. Chir.) PILULE: PLUMBI ACETATIS. ft. Plum- bi Acetatis gr. xii. Opii Purif. gr. vj. Con- serv. Cynosbati q. s. M. fiant pil. xii. One may be given thrice a day. Gleets are, perhaps, the only cases, in which surgeons can employ these pHls. . pilule: sode: cum sapone. ft. Sod® 3j. Saponis 3j. M. Fiant pil. xii. Four may be given thrice a clay, in cases ol POLYPUS. lbtonchoceie, and indurations of the absor- bent glands from scrofula. PILULE ZINCI SULPHATIS. R. Zinci Sulphatis, 3 * j - Terebiuthinse q. s. Fiant pi!, lx. One, or two, are occasionally given, in cases of gleets, thrice a day. PLAN 1'ARIS MUSCLE. This long slen- der muscle of the leg is said to be sometimes ruptured, particularly in dancing and leap- ing. The surgeon can do little more than advise rest, and the same posture of the limb, as in the rupture of the tendo Achillis. (See Tendon.) POLYPUS, (from .-a row;, many, and a foot.) A kind of tumour, w hich is gene- rally narrow where it originates, and then becomes wider, somewhat like a pear ; which is most commonly met with in the nose, uterus, vagina, andjantrum ; and which received its name from an erroneous idea, that it usually had several roots, or feet, like polypi, or zoopkites. Polypi more frequently grow in the cavity of the nose, from the Schneiderean mem- brane, than any other situation, and are visibly of different kinds ; some being red, soft, and sensible ; but free from pain, and exactly like a piece of healthy flesh. This, which has been termed the fleshy polypus , is the most common, and fortunately the most easy of cure. Other polypi are called ma- lignant, being hard, scirrhous, and painful : some are said to be even capable of con- version into carcinoma. Richter describes another kind of nasal polypus, which is pale, very tough, and secretes a viscid discharge ; which undergoes an alteration of its size with every change of the weather; and which is rather a relaxation, or elongation, of a part of the Schneiderean membrane, than a polypous excrescence. The whole membranous lining of the nostrils is some- times relaxed, and thickened in this manner, so as nearly to till all the cavity of the nose ( Jinfangsgr . der Wundarzn. B. 1, Knp. 21.) Mr. Pott has taken great pains to explain, that there is one kind of polypus, originally benign; another originally malignant. He states, that those which begin with, or are preceded by considerable, or frequent pain in the forehead and upper part of the nose, and, which, as soon as they can be seen, are either highly red, or of a dark purple colour ; those, which from the time of their being first noticed, have never been observed to be sometimes bigger, sometimes less, but have constantly rather increased ; those, in which coughing, sneezing, or blowing the nose, gives pain, or produces a very disa- greeable sensation in the nostril, or forehead; those which, when within reach, are painful to the touch, or which, upon being slightly touched, are apt to bleed ; those which seem to be fixed, and not moveable by the action of blowing the nose, or of driving the air through the affected nostril only (when the polypus is only on one side;) those which are incompressibly hard, and which, when pressed, occasion pain in the corner of the eye, and forehead, and which, if they shed anv thing, shed- blood ; those which hv Tor. I f 46 361 adhesion occupy a very considerable space, and seem to consist of a thickening, or of an enlargement of all the membrane cover- ing the septum narium ; those which some - times shed an ichorous, offensive, discolour- ed discharge ; and those, round whose lower part, within the nose, a probe cannot easily and freely be passed, and that to some height, ought not to be attempted, at least by the forceps, nor indeed by any other means ; and this for reasons obviously dedu- cible from the nature and circumstances of the polypus. On the one hand, the very large extent and quantity of adhesion will render extirpation impracticable, even if the dis- ease could be comprehended within the for- ceps, which it very frequently cannot ; and on the other, the malignant nature of the distemper may render all partial removal, all unsuccessful attacks on it, and indeed any degree of irritation, productive of the most disagreeabie consequences. But, the polypi, which are of a palish or grayish light-brown colour, or iook like a membrane just going to be sloughy ; which are seldom or never painful, nor become so upon being pressed ; which have appeared to be at one time larger, at another less, as the air has happened to be moist or dry ; which ascend and descend freely by the action of respiration through the nose ; which the patient can make to descend by stopping the nostril which is free, or even most free, and then driving the air through that which the polypus possesses ; which when pressed give no pain, easily yield to such pressure, be- come flat thereby, and distil a clear lymph ; and round whose lower and visible part a probe can easily, and that to some height, be passed, are fair and fit for extraction ; the polypus, in these circumstances, fre- quently coming away entire : or, if it does n >t, yet it is retnoveable without pain, he- morrhage, or hazard of any kind ; the se- cond of which circumstances Mr. Pott can with strict truth affirm, he never yet met with when thedisease was at all fitforthe operation. Of the benign kind of polypus, fit for ex- traction, there are (says Mr. Pott) two sorts, whose principal difference from each other consists in their difierent origin or attach ment. That which is most freely moveable within the nostril, upon forcible respiration ; which has been found to be most liable to chanoe of size, at different times and seasons; which has increased the most in the same space of time ; which seems most limpid, and most freely yields lymph upon pressure, has its origin most commonly by a stalk or kind of peduncle, which is very small, com- pared with the size of the polypus. The other which, although plainly moveable, is much less so than the one just mentioned, which has been less liable to alteration from air and seasons ; and which has been rather slow in arriving at a very troublesome size, is most frequently an elongation of the membrane covering one of the ossa spon- giosa. These latter may be extracted with no kind of hazard, and with very little pain, and hemorrhage : but the former require 'POLYPI S. 362 the least force, ami mostly come away en- tire ', while the others often break, come away piecemeal, and stand in need of the repeated use of the forceps. (Pott, on the Polypus of the Nose.) Mr. John Beil criticises the distinctions drawn by the preceding writer, and he says, that a polypus is never mild, and never ma- lignant ; time, and the natural growth of the tumour, and the pressure it occasions within the soft and bony ceils of the nostrils and jaws, must bring every polypus to one inva- luable form, in its last and fatal stage. Po- lypus, says Mr. John Bell, is indeed a dread- ful disease ; but it becomes so by a slow progression, and advances by gradations easily characterized. Every polypus in its early stty r e, is, according to this writer, a small moveable tumour, attended with a sneezing and watering of the eyes ; swelling in moist weather ; descending with the breath ; but easily repressed with the point of the finger. It is void of pain, and not at all alarming ; it may also be easily extracted, so as to clear for a time the passage for the breath. Yet this little tumour, simple as it may appear, is the germ of a very fatal and loathsome disease, and this easy extraction often the very cause of its appearing in its most malignant form The more easily it is extracted, (says Mr. J. Bell,) the more easily does it return ; and whether carelessly ex- tracted, or altogether neglected, it soon re- turns. But when it does return, it has not really changed its nature ; it has not ceased to be in itself mild, it is then to be feared, not from its malignity, but from its pressure among the delicate cells and membranes of the nose. It soon fills the nostrils, obstructs the breathing, and causes indescribable anx- ieties. The tears are obstructed, and the eyes become watery from the pressure on the lachrymal sac ; the hearing is in like manner injured, by the pressure of the tu- mour against the mouth of the eustachian lube ; the voice is changed, and its resonance and tone entirely lost, by the sound no lon- ger passing through the cells of the nose and face. The swallowing is in some de- gree affected by the soft palate being depress- ed by the tumour. The pains arising from such slow and irresistible pressure are un- ceasing. From the same pressure the bones become carious, and the cells of the face and nose are destroyed by the slow growth of the swelling. It is not long before the tu- mour begins to project from the nostril in front, and over t lie arch of the palate be- hind. One nostril becomes widened and thickened ; the nose is turned towards the opposite side of the face, and the whole countenance seems distorted. The root of the nose swells, and becomes putty, the fea- tures tumid and flabby, the face, yellow, and the parts round the eye livid. The patient is affected with headachs, which seem to rend the bones asunder, and with perpetual stupor, and dozing. The bones ore now ab sorbed, and the membranes ulcerate ; a foul and fetid matter, blackened with blood, is discharged from the nostrils, and excoriates them. The blood-vessels next give way, ami sudden impetuous hemorrhages weaken the patient ; the teeth fall from the sockets, and through the empty sockets a foul and fetid matter issues from the antrum. Now the disease verges to its conclusion The patient has terrible nights, and experi- ences a sense of suffocation. The repeated loss of blood renders him so weak, that he cannot quit his bed for several days together ; and when he does get up, he is (to use Mr Bell’s words) pale as a spectre, his lips co- lourless, and his face like wax, yellow, and transparent. He now suffers intolerable pain, while his saliva is continually dribbling born bis mouth, and a fetid di-charge from his nose. In this state, he survives a few weeks ; during the last days of his illness, lying in a state of perpetual stupor, and dy- ing lethargic. Mr. J. Bell afterward ob- serves, that “ if horrid symptoms could es- tablish the fact of malignity, there is not to be found in all nosology a more malignant disease than this : but aneurism, though it destroys the thigh bone, the sternum, or cra- nium, is not accounted malignant ; neither is polypus malignant, though it destroys the cells of the face, and penetrates even through the ethmoid bone to the brain. These consequences result merely from pressure.” (John Belt's Principles of Surge- ry, Vol. 3, Purl 1 ,p 90 — 92.) in April, 1817, there was a boy in St. Bar- tholomew’s Hospital, only twelve years old, who had just fallen a victim to the ravages ot the largest and most disfiguring disease within the nose which I have ever had an opportunity of beholding. The tumour be- fore death had expanded the upper part of the nose to an enormous size, while below the left nostril was immensely enlarged The distance between the eyes was extraor- dinary, being more than four inches. The left eye vvu3 affected with amaurosis, brought on by the pressure of the swelling ; the right retained to the last the faculty of seeing. The tumour nearly covered the mouth, so that food could only he introduced with a spoon, and an examination of the slate of the palate was impossible. About a fortnight before death, the leg became paralytic, and during the last week of the boy’s existence, an incontinence of the urine and feces pre- vailed. On examination of the head after death, a good deal of the tumour was found to be of a cartilaginous consistence, and, what was most remarkable, a portion ot it, which was as large as an orange, extended within the cranium, where it had annihila- ted the anterior lobe ol the left hemisphere of the brain. Yet, notwithstanding this ef- fect, the boy was not comatose, nor insensi- ble, till a few hours before his decease. All the surrounding bones had been more or less absorbed, and the place from which the ex- crescence first grew could not be determined The celebrated Professor Richter has de- nied the validity of (he objections urged by Pott against attempting to relieve the pa- tient : neither the malignant nature ot a po- lypus, it» adhesions, iinn)ovcubleness t nice- POLYPUS. 363 rations, dot disposition to hemorrhage, &,c. are, according to Richter, any* apology for leaving the disease to itself. (See An- fangigr. dtr IVundarxn. B. I, cap. 21.) Mr. J. Bell refutes the common notions, that polypi may be caused by picking the nose, blowing it too forcibly, ‘colds, and local injuries. He asserts, that a polypus is not in general a local, solitary tumour: he has only found it so in three or four instances. Both nostrils are usually affected. He states, that no finger can reach that part of Ihe nos- tril whei e the root of the swelling is situated, as it is deep and high in the no-trils, towards tile throat, and near the opening of the eus tachian tube. The finger cannot be intro- duced further than ihe cartilaginous wing of the nose extends and can hardly touch the anterior point of the lower spongy bone. The anterior and posterior chambers of the nostril are separated Irom each other by a narrow slit, which (he finger can never pass, and which is divided, in consequence of the projection ot the lower spongy bone, into two openings, one above, the other below. Through these the heads of the polypus pro- ject. These tangible parls of the tumour, however, are very distant from its root, which is in the highest and narrowest part of the nostril. (See p. 103, lu4.) Mr. J. Bell also says, that three or four polypi are often crowded together in one nostril, while more are formed, or forming, in the other. He dwells upon the difficulty and imprac- ticableness of tying the root of a polypus; and explains, in all attempts to extirpate such tumours, the surgeon’s aim should be to reach a point nearly under the socket of the eye, in the deepest and highest part of the nostrils, and that instruments can only do good w hen introduced beyond the narrow cleft, formed by the projection of the spongy bone. (P. 108.) Though Mr. John Bell is probably right in his opinion, that polypi do not proceed from the several circumstances which have been above noticed, yet they are, in most instan- ces, diseases of an entirely local nature. Certainly, in general, it is very difficult to describe what is the cause of a nasal polypus. Frequently the patient is, in other respects, perfectly well ; and after the removal of the tumour, no new one makes its appearance. In this circumstance, it must originate from a local cause, though it is generally difficult to define what the nature of this is. Some- times several catarrhal symptoms precede the polypus, and, perhaps, constitute its cause. It is possible, they may only bean effect of the same cause which gives bir h to the tumour ; but, no doubt, they are some- times the effect of the polypus itself. Some- times, perhaps, a faulty slate of (he constitu- tion really contributes to the disease ; for se- veral polypi frequently grow in both nostrils, and even in o:her situations at the same time ; are reproduced immediately after their removal ; and the patient often has an unhealthy appearance. Notwithstanding it has been asserted, that a solution of the mu riate ot ammonia, frequently injected into the nose, sometimes disperses polypi, the ef- ficacy of tile remedy remains unestablished by experience ; as, indeed, the very nature of the disease might lead one to anticipate. An operation affords the only rational chance of a cure. There are four modes of extirpating a na- sal polypus : viz. extracting it with forceps ; tying it with a ligature ; cutting it out ; and destroying it with caustic. Extraction is i he most common and pro- per meihod. It is performed with the ordi- nary polypus forceps, the blades of which have holes in them, and are internally ra- ther rough, in order that they may take hold of the tumour more firmly, and not easily slip off it. The front edge of each blade must not be too thin and sharp, lest, with its fellow, it should pinch off a portion of the polypus. The blades must necessarily have a certain breadth ; for when they are too small, they cannot properly take hold of and twist the tumour. When the handles are rather long, the instrument may be more firmly closed, and more conveniently twisted. However, the forceps is not applicable to all cases. The anterior part of the polypus, lying in the nostril, distending, and totally obstructing it, is sometimes quite hard, and when theforeeps is introduced, it presses the blades in such a manner, from each other, as it lies between them, that the instrument cannot be introduced sufficiently far to take hold of the tumour at a proper depth. If introduced fo a proper distance, it cannot be closed. In such a case, says Richter, one might, perhaps, advantageously make use of a pair of forceps, the pieces of which may be separately introduced, and then fastened together again at Ihe joint, and the blades of which diverge from each other behind the joint, and touch again at their extremities The anterior indurated portion of the poly- pus lies in the interspace, and does not pre- vent the closure of the instrument. It is generally deemed of importance to take hold of the polypus with the forceps close to its root ; and, indeed, when this rule is observed, the whole of the polypus, to- gether with its root, is commonly extracted, and there is less reason to apprehend he- morrhage, which is naturally more profuse when the polypus is broken at the thick, mid- dle portion of its body. It is also a rule fre- quently easy of observance, especially when the polypus is not too large. But in many instances the tumour is so large, and the nos- tril so completely occupied by it, that it is impracticable to get hold of its root. In tins circumstance it is often altogether impossi- ble to discover even where the root lies. Here we must be content to take hold of the polypus as high as possible. The conse- quences are of two kinds. The tumour sometimes gives way at its root, though it be only taken hold of at its anterior part ; and, in other cases, breaks where it is grasped, a portion being left behind, and a profuse he- morrhage ensuing. This is, however, void of danger, if the surgeon does not waste time in endeavouring to suppress the effu- POLYPUS 364 sion of blood ; but immediately introduces the forceps again, grasps the remnant piece, and extracts it. The most infallible method of diminishing the bleeding, is to extract what remains behind at its root. In this way, a large polypus is frequently extracted, piece- meal, without any particular loss of blood. After the polypus has been propelled as far forward, into the nostrils, as it can be by blowing strongly through the nose, its ante- rior part is to be taken hold of by a small pair of common forceps, held in the left hand ; and is to be drawn gradually and slowly out, to make room for the introduc- tion of fhe polypus-forceps into the nostril. The more slowly we proceed in this ma- noeuvre, the more the polypus is elongated, the narrower it becomes, the greater is the space in the nostril, for the introduction of the polypus-forceps, and the higher can this instrument grasp the tumour. Atier it has taken hold of the polypus as high as possi- ble, it is to be twisted slowly round, and, at the same time, pulled outward, til! the tu- mour breaks. It is a very important maxim, rather to twist the instrument than to pull it, and thus rather to writhe the polypus off than to drag it out. The longer and more slowly the polypus-forceps is twisted, the more the part where the excrescence separates is bruised, the less is the danger of hemor- rhage, and the more certainly does the tu- mour break at its thinnest part, or root. When the extraction is done with violence and celerity, only a piece is usually brought away, and we run hazard of occasioning a copious bleeding. As soon as the polypus has given way, the surgeon is to examine whether any part re- mains behind. When the polypus is very narrow at the place where it has bf-en broken, and the patient can breathe through the nose freely, there is reason to presume that the polypus has given way at its root, and that none continues behind. The finger, if it can be introduced, procures the most certain information ; or the probe, when this, for want of room, cannot be employed. The ancients proposed several means for the ex- tirpation of the remaining piece of polypus ; but they are, for the most part, objectiona- ble. It is best to introduce the forceps again, under the guidance of the finger, or probe, and thus pinch, and twist off, the part con- tinuing behind. Hemorrhage invariably succeeds the ope- ration ; and by many writers has been re- presented as exceedingly perilous and alarm ing. But it is not constantly so, and in some cases is quite insignificant. Frequently, however, it is really serious ; and as the sur- geon can never know beforehand to what extent it will happen, he is always to furnish himself, before the operation, with the most effectual means for its suppression. The danger of hemorrhage may always be less- ened, as was before mentioned, by slowly twisting the polypus at its root, in preference to pulling it directly out. When only a por- tion of the tumour has been extracted, the surest mode of slopping the effusion of blood is to extract the remaining part without Ge lay. When the polypus has given way at ite root, if there should be profuse bleeding, we may first try ice-cold water and strong brandy, which may either be sucked or in- jected into th§ nose. This single remedy proves effectual in numerous instances. If the hemorrhage should still prevail, it may always be checked with certainty, how co- pious soever it may be, in the following man- ner. Roll a considerable piece of lint, as fast as possible, round the extremity of a probe ; wet it completely through with a strong solution of the sulphate of zinc ; in- troduce it into the nostril, and press it as strongly as possible against the part whence the blood issues. When the nostril is very much dilated, the fingers may be used for this purpose with more advantage than the probe. The point from which the blood is effused, may easily be ascertained, by press- ing the finger on various points. As soon as the blood ceases to flow, we may conclude that the finger is on the situation of the he- morrhage. This method is so efficacious, that there is seldom occasion for any other. When the bleeding point lies deeply in the nostril, it might be difficult to reach it with the finger. At all events, we may then em- ploy a plan which has been strongly praised in urgent cases. A piece of catgut may be introduced into the nostril, and by means of a pair of for ceps, be brought out of the mouth. A roll of lint is then to be attached to it, and drawn through the mouth into the nose ; thus the posterior aperture of the nostril may be stopped up. Then the nostril in front is to be filled with a sufficient quantity of lint, moistened in the solution of zincum vitrio- latum. The objections to extracting some polypi, says Richter, have been much exaggerated. When the polypus is so large, that its root cannot be got at, its anterior part is to be taken bold of, and the tumour extracted piecemeal. It has already been noticed, that this practice is free from danger. Ex- perience does not prove, that the polypus, which often bleeds profusely, is apt to occasion a violent hemorrhage in the opera- tion ; and even if it should do so, powerful measures may be adopted for the stoppage of the bleeding. The malignity and ulcera- tions attending a polypus, are no objections to the operation ; but are rather motives for its being promptly performed, as delay must occasion more manifest and urgent danger. If the polypus should be here and there adherent to the membrane investing the nostrils, it is proper to separate it before the operation. This object cannot be accom- plished by straight inflexible instruments such as have been invented by various surgeons. It may be very conveniently done, according to Richter, with thin, long, flat pieces of tortoise-shell, introduced as deeply as possible into the nostril, on every side of the polypus. As it can seldom be known with certainty, a priori, that ad- hesions are not present? it is proper whene- I'OLYl'Ufe 3(i5 ver the tumour is large, to introduce these instruments before the operation. Sometimes, the greatest part of the polypus extends backward, hanging down behind the palatum molle, towards the pharynx. If there should be but little of the polypus visible in the nostril, its extraction must be performed backward, in ihe throat. This is usually done with a pair of curved polypus forceps, which is to be introduced through the mouth, in order to seize and tear off the tumour as high as possible above the soft palate. Care must be taken not to irritate the root of the tongue, or else a vomiting is produced, which disturbs the operation. When the polypus cannot be properly taken hold of, we may, according to the advice of some surgeons, divide the soft palate. But this is very rarely necessary. As, by this mode, the polypus is not twisted, but pulled away, the hemorrhage is, in general, rather copious. If a fragment of the tumour should remain behind, it may commonly be extract- ed through the nose. Some recommend, for the extraction of polypi in the throat, a ring, consisting of two semicircular portions, with a kind of groove externally, which are capable of being opened and shut, by being fixed on the ends of an instrument constructed like forceps. A ligature is to be placed round the ring, and its end is to be brought to the handle of the instrument, and held with it in the hand. The instrument is to be intro- duced into the mouth, under the polypus, and expanded as much as the size ot the tumour requires. Its ring is then to be carried upward, over the polypus, so as to embrace it ; and afterward is to be shut., whereby the noose, after being carried up- ward, is disengaged from the ring. The noose is to be pushed as high as possible over the tumour, by means of forceps, and the extremity of the packthread is then to be drawn, so as to apply the noose tightly round the polypus. When this is done, the ring of the instrument is to be turned round firmly closed, and placed in front of the polypus, on the noose, in such a way, that the packthread is to lie between two little pegs, made for the purpose, at the ends of the ring. On drawing the packthread firmly, and pressing the instrument at the same time downward so as to make it act like a lever, the polypus in general easily breaks. Another peg projects in the direction of the ring, so as to prevent the ligature from in- sinuating itself within the circle. (See Theden’s Bemerk. Part 2. and Platt 6. fig. 1. in Richter's Jlnfangsgr.) The employment of this instrument, however, is attended, says Richter, with many difficulties, and little advantage. Po- lypi in the throat are most conveniently extracted by the ordinary straight polypus forceps, with which they may be seized, and gradually drawn out through the mouth. The tumour generally allows itself to be drawn out without trouble, and the inclina- tion to vomit, which at this moment occurs, also contributes to propel it outward. When it is so stretched, that it cannot be drawn out further, without considerable force, a spatula is to be introduced into the mouth, and to be carried as high as possible behind the polypus, in order to press it downward, toward the root of the tongue. When the tumour is at the same time forcibly pulled outward by the forceps, it usually gives way. When the polypus is situated partly in the throat and partly in the nostril, though it admits of being extracted, in the same way, through the mouth, yet its anterior part often continues attached, and must afterward be saparately removed through the nostril. It is also frequently adviseable to twist off the anterior portion of the polypus first, by which the mass in the throat is often ren- dered so loose, that it can be easily extract- ed. Whenever it is conjectured, that the polypus will come away in two pieces, it is always preferable first to extract the part in the nostril, and afterw ard that in the throat because tiie separation of the last is con- stantly productive of more bleeding, than the removal of the first. Sometimes, the following plan succeeds in detaching the whole polypus at once. Both the part iri the nostril, and that in the throat, are to be firmly take hold of w ith the for; ms, and drawn at first gentlv and then more f cibly,, backward and forward. By such repeated movements, the root is not unfrequently broken, and the whole polypus brought away from the mouth. Frequently the polypus grow s again. Po- licy requires that the patient should be apprized of this beforehand. Some of the root remaining behind, may often be a cause of the relapse. Hence the surgeon should examine carefully, after the operation, the part at wnich the root of the polypus was situated, and separate, and twist off, most diligently, with the forceps, any fragments that may still continue attached. I he re- currence of the disease, however, may 'arise from other causes. The tumour is occasional- ly reproduced, after it has been extracted in the most complete manner; and doubt less, this circumstance is sometimes ow ing to the continued agency of constitutional causes, which so often remain undiscovered and unremoved Sometimes, also, the re- currence of the disease is owing to a local morbid affection oi the Schneiderian mem- brane, or of the bones situated beneath the root of the poly [ius. Richter, in this case, approves ot the cautery ; but few English surgeons will coincide w ith him. The po- lypus, sometimes observed subsequently to tin operation, is fr< quently not, in fact, a a new' substance, but only a part of the original tumour, not previously noticed by the surgeon. Sometimes it occurs, thai a smaller and larger polypus are found in the nose at the same time The larger one is extracted, while the other remains undisco- vered ; and when it has increased in magni- tude, it is apt to be mistaken for a repro- duction of the one previously extirpated. (See Richter's Anfangsgr. drr Wuvdarsn , B 1. Kap. 21 A POLYPUS. Ligature. As the extraction of the poly- pus is invariably attended wiih hemorrhage, which is sometimes profuse, another more modern method of cure has been proposed as more convenient and secure. This con- sists in tying the root of the tumour with a ligature, by which the polypus is thrown into the state of inflammation, suppuration, and sphacelus ; and at length becomes de- tached. Many instruments have been in- vented for applying the ligature ; but Levret’s double cannula seems to be the best. Through this, a silver wire is to be introdu- ced, so as to form a noose at the upper end of the instrument, proportioned in size to the anterior part of the tumour, situated in the nostril. t he two ends of the wire are t> hang out of the two lower apertures of the dou! e ^nnula ; and one of them is to be iastened to a small ring on its own sid8 of the instrument. The other is to remain loose. Ti.e wire must be made of the purest silver, and ought to be as flexible as possible, tnat it may not readily break It must also not be too thin lest it should cut through the root of the polypus. The can- nula is to be somewhat less than five inches long By the assistance of this cannula, the noose is to be introduced into the nose, and put round the polypus. But as the cannula, which is usually constructed of silver, is straight and inflexible, while the inner surface of the nostril is preternaturally arched, especially when much distended by the polypus, it is easy to discern that its introduction must be attended with consi- derable difficulty, in fact, it can seldom be introduced as deeply as the root of (he polypus. There are two ways of avoiding this obstacle. The cannula may either be passed under the polypus, over the ossa palati, which present a tolerably straight surface, or it must be curved a little. Per- haps, a tortoise-shell cannula, says Richter, might be convenient. The noose is to be applied in the follow- ing manner. r lbe polypus is to be taken hold of with the forceps, and drawn a little out of the nose. The noose is then to be carried over the forceps and polypus, into the nostril. In order to carry it as high as possible, it is necessary not to push the can- nula st'-aight forwards into the nose, but to move it from one side of the polypus to the other. The more deeply the instrument has entered the nose, the more of the loose end of the wire must be drawn out of the lower aperture of the cannula, so as to contract the noose, which otherwise might stop in the nostril, and not be carried suffi- ciently high. The elasticity of the silver wire tends to assist in raising it over the p ! vpus, and hence, it is more easy of appli- c lion than a more flaccid kind of a ligature. When there is cause to conclude, that the polypus is complicated with adhesions, they must be previously broken, in the way already mentioned. As soon as the noose has been introduced as deeply as possible, the loose extremity of the wire is to be drawn out. of the lower aperture of the cannula, and rolled round the ring on that side of the instrument. Thus the root of the polypus suffers con striction. The wire must not be pulled too forcibly, nor yet too feebly. In the first circumstance, it readily cuts through the root of the polypus: in the second, great tumefaction of the excrescence, and many inconveniences arise, which a tenser state of the wire prevents. As the noose gradually makes a furrow where it surrounds the polypus, it grows slack after a short time, and no longer constricts the tumour. One end of the wire, therefore, is to be daily unfastened, and drawn more tightly. The more tense it is kept, the sooner the separa- tion of the polypus is brought about. Hence, when it is particularly indicated to produce a speedy attachment of the polypus, the wire should be tightened, at least, once a day. In this mannner the cannula is to remain in the nose until the noose is detached, to- gether with the poiypus. There is another method of tying the tumour, without leav- ing the cannula in the nose. After the noose has been introduced as far as possible into the nostril, the two ends of the wire are to be twisted round the two rings, and the cannula is to be turned round a couple of times. The wire is then to be unfastened from the rings, and the cannula withdrawn. In this way the noose is made to embrace the poi pus, round which it remains fastly applied. Whenever it is wished to produce a greater constriction, the cannula may be again introduced into the nose, the ends of the wire fastened to the rings, and the in- strument turned round again ; after which it is to be taken away, as before. As the cannula, when it continues long in the nose, may occasion pain, and other inconveni- ences, the last method seems preferable to the former. However, introducing and withdrawing the cannula every day, as Richter adds, may, perhaps, be equally trou- blesome and painful. The cannula for this purpose being necessarily straight, is by no means handy. One might, at all events, make use of a single cannula, the upper opening of which is divided by a bridge ; this could be much more conveniently twist- ed than a double one. Although the ligature has been very much praised by some of the moderns, it is at- tended with so many difficulties, that in the majority of cases, the forceps is infinitely preferable. Hemorrhage is the only incon- venience, for which extraction is abandon- ed for the employment of the ligature. But this, as was before stated, is much less dan gerous than is represented. The inconve- niences of the ligature are far more serious, and numerous. The cure bv the ligature is al- ways accomplished with much less expedi- tion than by extraction. When the polypus is of such a size as to occupy the whole of the nostril, it is generally impracticable to in- troduce the noose to a sufficient depth POLYPI S. •The figure oi the polypus renders it almost impossible to tie its root ; for commonly the tumour expands very much before and behind, and the wire must be brought over the posterior part of the polypus, ere it can be applied to its root. In general, also, the noose only includes the front part of the polypus, while the root, and back portion remain untied, and consequently do not become detached. — It is, indeed, asserted, that the ligature, when only applied to the front part of the polypus, is capable of bring- ing about inflammation, suppuration, and a detachment of the whole of the tumour. This may sometimes be the case; but ana- logous instances prove, that it is undoubted- ly not constantly so. The ligature seldom accomplishes an entire destruction of the disease, and there is usually reason to appre- hend its recurrence. If the polypus be very large, and the w hole nostril occupied, it is frequently utterly impossible to introduce the wire ; and when this is done, the front of the tumour alone can be tied. The polypus nasi is commonly highly sen- sible, and consequently, tying it proves very painful. As soon as the noose is drawn tight, not only the polypus inflames, but the whole extent of the Schneiderian mem- brane. The pain and inflammation often extend even to parts at some distance, such as the throat, eyes, he. occasioning acute fever, which requires the strict observance of low diet v the exhibition of cooling physic, and the evacuation of blood Hence, it is adviseable in many cases, to prepare pa- tients for this treatment, by diet and medi- cines. When the polypus is tied, it swells very much, and all the complaints which it pre- viously caused are exasperated. But, in particular, the part situated in the throat, sometimes obstructs deglutition and respi- ration, in such a degree, that prompt re- lief becomes necessary ; and one of the best plans for affording it, is to make a few punctures in the tumour. These excite a bleeding, that very speedily lessens the swelling, but is sometimes difficult to check. Hemorrhage from a part of the polypus that is tied, is most effectually stopped by twisting the wire so tight, that it closes the arteries distributed to it. The wire sometimes breaks off' close to the lower aperture of the cannula, in con- sequence of being twisted so much and thus the progress of the cure is interrupted. A new wire may be introduced ; but it is difficult to apply it exactly in the situation of the other. A fresh place is commonly tied, which is almost the same thing as com- mencing the cure anew. It is better to prevent this interruption of the treatment by employing very flexible w ire, made of the purest silver ; and by not twisting and untwisting regularly the same extremity of it, but sometimes one and sometimes the other. A strong piece of catgut might be a very good substitute for silver wire. Immediately the polypus is tied, it swells, inflames, and becomes painful; in. a few days, it becomes shrunk, free from pain, and sphacelated. The fetid discharge now occasions considerable inconvenience to the patient, and ought to be washed awrny by repeated injections. Towards the 'ter- mination of the case, the surgeon ought to take hold of the polypus with the forceps, to try whether any of it is loose. When the polypus is extracted, one may inject a solution of alum, tor a day or two after- ward, in order to diminish the effect of the irritating discharge on the Schneiderian membrane, and the suppuration in the situa- tion of the ligature, as it is sometimes pro- fuse, and of long duration. Though one might also tie polypous tumours in the throat; and, indeed, the introduction of the cannula through the mouth, and the application of the noose, would be attended with no great difficulty; and, though the treatment might be rendered more tolerable to the patient, by withdraw- ing the cannula afier tw isting the wire ; yet, the swelling of the tied portion of the tumour would, probably, create immense inconve- nience. In this case, therefore, extraction usually merits the preference, and the liga- ture is only fit to be practised in the throat, when tin* polypus is very small, or there is some especial cause forbidding extraction. When deglutition and respiration are impe- ded by the swelling of the tied portion of the polypus in the throat, the swollen part must be scarified by means of the pharyngo • tomus. so as to excite a bleeding, ai.d thereby produce a diminution of the swell- ing. The noose is to be frequently and strongly tightened, in order to accelerate the detachment of the polypus, and shorten the inconveniences. When the excrescence has not only descended towards the pha- rynx, but also into the nostril, its front por- tion is to be tied first. The result of this may be, such an inflammation and suppura- tion of the whole polypus, that, after the separation of its anterior portion the pos- terior one may also become detached, or at least, easy of removal. Caustics. The cautery, formerly recom- mended for the cure of the polypus nasi, is now almost entirely rejected, and indeed, in the manner it w r as customary to use it, little good could be done. It was applied to the anterior surface of the tumour in the nostril, and its employment was repeated every time the slough separated. Its opera- tion could naturally be but of small extent, as it only came into contact with a trivial portion of the polypus. Its irritation aug- mented the determination of blood to the excrescence, and accelerated its growth ; w hile as much ot the the tumour was repro- duced. ere the slough separated, as was thus destroyed; and the design of completely extirpating the disease, in this way seldom or never proved successful. However, says Richter, there is one particular example, where the cautery is the only means from which relief can be derived ; and, used in a certain way, it always speedily produces the desired effect . POLYPUs Tliere are some nasal polypi, much dis- posed to profuse bleeding. Touching them in the gentlest manner, and every trivial con- cussion of the body, give rise to hemorrhage. The patient is exceedingly debilitated by re- peated loss of blood ; his countenance is pallid; his feet swollen; he is affected with hectic fever; and faints whenever there is any considerable bleeding. Doubtless, exirac- tion,in this case, is a very precarious method, as the patient is so circumstanced, that any copious effusion ot blood must be highly perilous. Sometimes the polypus is, at the same time, so large, and the nostril so com- pletely occupied and distended, that it is impossible to apply a ligature. Such is the ease, to which alone the cautery promises assistance, (Richter.) In employing the cautery, (says the latter author,) the object is not to effect, by its direct agency, a gradual destruction of the polypus ; but to excite such an inflammation, and suppuration, of the whole of it, as shall lead to this event. To fulfil this purpose, a common trocar, three inches long, may Jae used. The cannula ought to be two inches shorter than the trocar, whereby the latter may protrude from it so far ; and it should be constructed with a handle. The cannula should be made wider than i’t is in common, so as to allow the trocar to be introduced, and withdrawn with facility. It is to be wrapt round with apiece of wet linen, and applied to the polypus. The red-hot trocar is then to be pushed into the tumour, as far as the cannula will allow it, which is, of course, two inches. When the patient entertains a dread of the actual cautery, Richter sanctions the introduction of a tent of the emplastrum cantharidum, ora tent smeared with butter of antimony, into the puncture of the un- heated trocar, and as soon as suppuration has taken place!, emollient and detergent lotions are to be injected. ( Richter's An- faitgsgr.) In England, the actual and potential cauteries are never used for the destruction of nasal polypi. Excision. In the treatment of the poly- pus, the use of cutting instruments has al- ways been reprobated, because they usually occasion a profuse hemorrhage, and c.tn hardly ever be passed, without mischief, to a sufficient dentil into the nose to divide the root of the tumour. Yet. there are instan- ces in which their use might be productive of advantage. The anterior part of the po- lypus, situated in the nostril, is sometimes so thick and hard that it is utterly imprac- ticable to introduce the forceps for the performance of extraction, or the cannula for the application of the ligature. In such a case, it might be a judicious step to cut off the front of the polypus with a sharp in- strument, of a suitable. shape, in order to make room for the use of the ligature, or forceps. The polypus is sometimes of a ligamentous structure, and neither admits of being tied hor extracted. There is no means of removing such a polypus except the knife, by which it b to be. cut away piecemeal. Mr. Whately, after tailing in several at- tempts to extract and tie a considerable po- lypus of (he nose, succeeded in cutting it out. He used a narrow, straight bistoury, with a probe point, having a sheath fixed upon* its edge, by a screw put into a hole in the handle. An eye was made at its point, to receive one end of a thread intended to be passed round the polypus, for the pur- pose of directing the knife to the extremity of the tumour. There was also a contri- vance by which the knife could be unsheath- ed at its extremity, the length of three-quar- ters of an inch. This was done by means of a screw, which might be fixed in another hole, by drawing back the sheath. By ex- posing such a length of edge only, the in- terior parts of the nose were defended from the danger of being wounded.” Whoever wishes a particular account of the manner of using the instrument, must consult Mr. Whately’s Cases of two extraordinary Po- lypi , §'C. 1805. In the polypus which arises from a relax- ation of the Schneiderian membrane, ex- ternal astringent applications may be first tried ; such as ice-cold w^ater, solutions of acetite of lead, alum, muriate of ammonia. &c. These remedies (says Richter) common - ly lessen it, and frequently, when it is not very large, accomplish its entire removal If this should not happen, there is no reason against putting a ligature round it. Here, also, w^e may venture to employ a cutting instrument, if it be in our power to do so ; which, as far as my experience goes, will very rarely be the case. But the practice of extraction is here prohibited. When the Schneiderian membrane is pre- ternaturally swollen all over the nostril, which is quite obstructed, the pervious state of the cavity is to be restored by the intro- duction of catgut or bougies. A thin piece is at first passed into the nose, and afterw ard a larger and larger one gradually, until the passage for the air is perfectly re-established. But usually, this relief is only of short dura- tion, as the nostril very soon closes again Hence, such patients are advised to make constant use of flexible tubes passed into the nose ; or, when this is too troublesome, to fill the nose regularly at bedtime w ith cat- gut, and take it out again in the morning. (See Richter's Anfangsgr. B. 1.) POLYPI OF THE UTERUS. Polypi of the uterus are of three kiuds, in respect to situation : they grow either from the fundus, the inside of the cervix, or the lower edge of the os uteri. The first case is the most frequent ; the last the most uncommon. Polypi of the uterus are always shaped like a pear, and have a thin pedicle. They are almost invariably of that species, which is denominated fleshy, hardly ever being scirrhous, cancerous, or ulcerated. A polypus of the first kind, grow ing from the fundus uteri, is very difficult to detect in its incipient state. While small, it pro- duces not the smallest perceptible change in fOLYPLfc. •U) { J the organs ol generation. As it enlarges, it distends the uterus, and often excites a sus- picion of pregnancy, which, however, a more attentive examination soon dispels. The swelling of the abdomen does not take place in the degree and space of time, which it does in pregnancy ; the menstrual dis- charge continues to flow ; the breasts do not become full ; and, in the progress of the case, no motion is to be felt. While the polypus lies in the uterus, its growth is slow. At this early period it frequently occasions profuse bleeding. Women, afflicted with the disease, are seldom pregnant, and when they are so, parturition commonly happens prematurely. However, they sometimes bold out to the end of the regular time, and experience an easy and safe delivery. As the polypus increases, it expands the os uteri, and at length protrudes into the vagina. This takes place either suddenly, from an accidental concussion of the body ; or slowly and gradually. In the latter cir- cumstance, pains similar to those of labour occur, and cause the tumour to be expelled into the vagina. As soon as it has arrived in this situation, and is no longer confined and compressed by the uterus, it begins to grow more rapidly, and gives rise to far more troublesome complaints ; for it presses the bladder and rectum, and thus, more or less, disturbs the evacuation of the urine and feces. But in particular, it causes repeated and profuse hemorrhages, which weaken the patient exceedingly, and often bring her to the brink of the grave. The root of the polypus is situated in the os uteri, and is there so compressed, that the blood in the tumour is prevented from returning through the veins ; consequently, all the vessels be- come turgid, and the above effusions of blood are the result. Though they generally cease spontaneously, the least circumstances cause their recurrence ; such as slight con- cussions of the body in riding, walking, &,c. In the mean while, a quantity of mucous and aqueq,i>s fluid is voided, by which the patient’s strength is more reduced. The polypus, the source of this blood and mu- cus, is frequently misunderstood, and the patient is in a perilous state. So necessary is it in cases of preternatural discharge , from the uterus, always to examine with the finger, per vaginam. At length, after the polypus has been some time in the vagina, it begins to pro- trude externally. This happens gradually or suddenly, from some effort or concussion of the body. Hence additional grievances are again excited. As the polypus cannot descend so low without dragging the fundus of the uterus downward Avith it, and occa- sioning a prolapsus of this organ, the pa- tient, in walking or standing, commonly experiences a very painful sense of dragging or stretching, in the pelvis. As the bladder and ureters are also forced into a deranged E osition, the evacuation of urine is, more or ;ss, disturbed, or rendered difficult. Lastly, the dribbling of the urine over the polypus, and the friction which the part accidentally Vox. II. 47 suffers, frequently cause it to inflame, and become painful, and ulcerated. A polypus, situated in the vagina, or pro truding from it externally, may easily be mistaken for a prolapsus uteri ; an error Avhich, though not difficult to avoid when a careful examination is made, may have very perilous consequences. The polypus is softer and less sensible than the uterus in the state of a prelapsus. The imperfect prolapsus uteri, in which this viscus is not turned in- side out, is betrayed by the os tincae, at the lower part of which it is plainly perceptible In this situation, the polypus may occasion- ally have a depression resembling the mouth of the w omb, but easy of discrimination from it. A probe can be passed deeply into the os uteri ; but, not so into this other opening. The polypus resembles an in- verted pear, that is, it is thickest beloAV, and becomes gradually thinner upward. The above species of the prolapsus uteri is thin- nest below 7 , and gradually increases in width upward. The fallen uterus may easily be pressed back, and when it is so, the patient experiences relief. The polypus does not admit of being pressed back, and, during an attempt to do this, the patient is put to much inconvenience. A probe may be in- troduced by the side of the polypus deeply to the fundus uteri. When passed by the side of the fallen uterus, it is, very soon stopped at the upper part of the vagina, which has sunk down with the cervix of this organ. A polypus, protruding externally from the vagina, may be much more easily distin- guished from a perfect prolapsus uteri, with out inversion. The os uteri at once'charac- terizes the uterus, as it can here not only be felt, but seen. A probe may be passed deeply into the vagina, along the side of the polypus ; but, not so by the side of the ute- rus, for reasons easy of comprehension. The figure of the tumour, and the state of the patient, on an effort being made to reduce the protruded part, also betray its real na- ture. The inversio uteri is usually the conse- quence of a difficult labour, arid hence is easily discriminated from a polypus, by its occasional cause. While the inverted ute- rus lies in the vagina, its shape is broad above and narrow 1 below ; whereas the po- lypus is thin above and broad below. Hence in cases of very large polypi in the vagina, the os uteri is but little dilated ; uffiile it is extremely distended by the incemplete de- scent of the inverted uterus itself. Here, likewise, the reduction of the part is at tended with relief ; while every effort to push back a polypus causes an aggravation of all the complaints. When the inverted uterus hangs out of the vagina, its figure, like that of the poly- pus, is thin upward, and broad downward ; and, like the latter tumour, has no aperture at its lowest part Here an erroneous opi- nion is very liable to be formed. An atten- tive observer, however, will easily avoid it. The inverted uterus includes a circular fold 370 POLYPUS. at its upper part, next to the orifice of the vagina. This fold is nothing less than the os uteri itself, through which the body of this viscus has descended. There is nothing of this kind to be felt in cases of polvpi. By the side of a polypus the finger or probe may be passed deeply into the vagina ; but not so by the side of the uterus. The root of the polypus is firm and hard to the touch , the upper thin [tart of the uterus, which is hollow, has a soft flabby feel. Useful light is also generally thrown on the case, by the above-mentioned occasional cause of the prolapsus uteri with inversion. However, in particular cases, the diagnosis is much more difficult, and the observations of a modern writer fully prove that it is al- ways difficult, and perhaps sometimes im- possible to distinguish a partial and chronic inversion of the uterus from a polypus. (IV.Newnham, Essay on the Symptoms-, Causes , and Treatment oj Inversio Uteri , with the His- tory of the successful Extirpation of that Or- gan during the Chronic Stage of the Disease , p 82, iyc. 8 vo. Lond. 1818 ; also First Lines of the Practice of Surgery, Vol. 2, p 317.) In the two last descriptions of uterine polypi, situated either on the inside of the cervix, or at the margin of the os uteri, the disease is, as it were, from its commence- ment in the vagina, and the tumour, when large, produces all the complaints attendii g polypi of the first kind, except frequent profuse bleedings. These seldom occur, and when they do, are slight, because the root of the polypus suffers no constriction in the os uteri. As the tumour descends out of the vagina, it occasions a prolapsus uteri without inversion, in addition to the other inconveniences. Experienceproves that uterine polypi, when once extirpated, have not that propensity to be Reproduced, which those of the nose have. Here, for obvious reasons, extrac- tion is not the right practice Sometimes, however, uterine polypi are met with which have such a thin and soft pedicle, that, al though they ought not to be pulled out, they admit of being twisted off with facility and safety. Also, numerous complaints of a serious nature are occasionally the result of tying a polypus of the uterus. In this cir- cumstance, after the ligature has been ap- plied some days, an attempt may be made to shorten such complaints, by twisting off the tumour altogether. This object is most conveniently performed with a pair of forceps made somethinglike Smeilie’s midwifery for- ceps. As the part of the polypus in the li- gature is constricted, thin, and already part- ly detached, the tumour, with a little cau- tion, may frequently be easily twisted off, ■without any material bleeding. The ligature is the must proper means of extirpating uterine polypi, and is here much more easy of application, than in the nose. Large as the polypus may be, there is always abundance of room for the introduction of ihe necessary instruments. The polypus of the uterus has commonly a thinner pedicle than that of the nose ; hence its cure by the ligature is more expeditious ; and on account of the greater room and more yielding na ture of the parts, the swelling of the tumour, after the ligature is applied, produces less inconvenience than in the same mode of treatment of nasal polypi. The inconve- niences which do arise are easy of remo- val ; for instance, the retention of urine may be relieved by the catheter; costive- ness by clysters, lie. Uterine are also less sensible than nasal polypi ; and hence, 'less pain and fever follow the application of a ligature to them. The fetid matter, formed as soon as the polypus sphacelates, has a free vent out, and may easily be washed away by injections. That the polypus cannot be tied while it lies in the uterus, is easily comprehensible. But immediately it has descended into the vagina, the operation may be undertaken, and may be performed with the same kind of double cannula, as was employed in the nose. However, here it is extremely re- quisite that the cannula should be rather longer than that already described, and somewhat curved. But, as the silver wire sometimes breaks, two other very conveni- ent instruments have been invented. The first is Levret s instrument. It con- sists of two silver cannula;, which are cur- ved in such a manner, and so united by a joint, that they are shaped like a pair of for - ceps. After introducing a ligature through the two tubes, so that its ends hang out of their lower apertures, the instrument is to be shut, and passed upwards into the vagi- na, over the polypus, on whichever side seems most convenient. Then it is to be opened, and the polypus is to be pushed through the two branches of the instrument, which is to be brought over the opposite side of the tumour. In doing this, the li- gature becomes applied round the root of the polypus, and forms a noose. The ex- tremities of the ligature are next drawn as tightly as possible out of the lower openings of the cannulas, and tied first in a surgical knot, and then in a slip-knot. The instru- ment is then shut, and the ligature con- stricts the root of the polypus. Afterward it is to be tightened daily, until the tumour separates. It is plain that this instrument has some defects, which, however, are easily amend- ed. It is very inconvenient that the surgeon should be obliged to have several such in- struments of various sizes and curvatures, so as to be able to select that which seems most calculated for the magnitude and shape of the polypus. And, as the size and figure of the polypus cannot always be ascertain- ed beforehand, it is often indispensable to try several instru nents, ere the most suita- ble one is found out, and such fruitless at- tempts must be distressing and painful to the patient. The worst is, that though the upper ends of the instrument were to touch, when the lower are tied together, yet there would always be a space between the two aper- tures, where no ligature would be applied to the root of the polypus, and where, con* POLYPUS 371 sequently, its separation would not easily be accomplished. The tubes may also bend w ith the force used in applying them, and the pain caused by the expansion of the in- strument would then be very considerably increased. All these defects are done away in the instrument described by Nissen, de polypis uteri, (See Richter's Chir. Bibl. 9. B. S. 613 ) It consists of two silver tubes, twelve inches in length, and as thick as an ordinary wri ting pen. Both are curved about as much as the os sacrum ; but, as they are made of pure silver, the curvature may easily be in- creased or diminished, according to circum- stances. Through each of the cannulae a strong ligature is 10 be passed, so that its ends hang out of the lower apertures, while its middle portion forms a noose between the upper apertures of the cannulae. . The tubes are to be kept together until they have been introduced into the vagina, as far as the root of the polypus. One is then to be held fast, while the other is to be carried round the tumour, to the opposite side of the cannulae that remains stationary. Thus the ligature becomes applied round the root of th# polypus. After introducing the finger into the vagina, to ascertain that the ligature lies in its proper situation, its ends are to be drawn through a small dou- ble cannula, which is only one third of an inch long, but so wide that it can be pushed over both the tubes a certain way w ith the finger, and the upper end of the long can- nulee with the aid of a sort of long probe, with a forked extremity. Then a third double cannula, through wffiicb the ends of the ligatures have likewise been passed, and the width of which is sufficient is to be pushed over the lower ends of the long can- nulae so as to unite them. The ligatures are next to be drawn tight in the ordinary way, and fastened to the rings. The manage- ment of this instrument is so easy as to need no further explanation. Besides the above instruments, many others have been devised and recommended for tying polypi of the uterus. In particular, one invented by Desault, claims the atten- tion of such surgeons as wish to be informed of others. Acute symptoms frequently follow the ap- plication of the ligature, and are either of an inflammatory or spasmodic kind. The former require antiphlogistic treatment. Sometimes fever arises, and the polypus becomes exceedingly painful ; in this case, venesection is necessary. Spasmodic symp- toms require the exhibition of opium. When this is ineffectual, and the symptoms are severe, it may be proper to slacken the liga- ture a little. As the polypus at first always swells, it produces great prp«sure on the adjacent parts. For this reason, it is gene- rally necessary, for the first few days, to draw off' the urine with the catheter, and to open the bowels with clysters. Sometimes hemorrhage takes place. This may gene- rally be suppressed with astringents ; but when they prove ineffectual; tying the liga- ture more tightly answers the purpose. The rest of the treatment resembles that of nasal polypi. When the polypus is large, it is often ne- cessary in the end to use forceps for its ex- traction. The inflammation, Iso occasionally form in the vagina, some of which have a broad basis, and others a thin pedicle. The last merit the appellation of polypi- Their ex- istence is easily ascertained by the touch. By making pres u re on the bladder and rec- tum, they occasion several impediments to the evacuation of the urine and fttces. They may be conveniently tied, by means of the double cannula. Should the polypus be situated at the lower part of the vagina, the cannulae would not be required. The liga- ture might be applied with the hand, and the tumour cut off below the constricted, part. There is still another kind ot tumour in ♦lie vagina, to be classed in the rank of po- lypi. It resembles, in many points, the po- lypus of the mucous membrane of the nostril, consisting altogether of the membranous lining of the vagina which, at the part affected, becomes relaxed, thickened, and elongated; hence the (uraour might be . ore properly termed aprolapsus of the membranous lining of the vagina, than a pulypus. When it resists the efficacy of astringent and corro- borant injections, if may be tied, or what is better, cut off. A polypus in the oesophagus renders de- glutition difficult ; and when of large size, puts an entire stop to it. When an inclina- tion to vomit is excited by irritating the throat with the finger, or a feather, the poly- pus, if situated tow ards the upper part of the tube, ascends in'o the mouth, so as to become visible. But as it impedes respiration dunng its residence in the inmitfa, the patient is soon necessitated, as it were, to swallow it again. When the polypus is situated far dowm the oesophagus, of course it cannot be brought into the mouth, and is very difficult to detect. The difficulty of swallowing, its only symptom, may result from other causes. In this case it is also incurable ; for it is impossible to take hold of it with instru- ments. An operation can only be practi- sed, when the polypus is situated in the upper part of the oesophagus. The tumour cannot be extracted ; and the tying of it is difficult. Polypi in the rectum may bp tied with the aid of the cannuiae. Excre c‘*nces in the meatus auditorius externus, resembling po- lypi, have been successfully extirpated by extraction, or rather by twisting them off. For many of the foregoing remarks, I am indebted to Richter, who has very ably treated of polypi in his Ansfangsg. der Wun - darzn. B. 1, Kap. 21. See also J. B. de Lamsweerde, Historia JValuralis Malorum Uteri, 12 mo. Lugd. 1700. P. G Schachev, Programma de Polypi*, Lips. 1721. G. F. Balt schmid, De Mola scirrhosa in ulero inverse extirpata, Jenee , 1754. C. Schunck , De polypo post febrern Epidemicum ex utero egresso. Witiemb. 1739. A. Levret, Obs. sur la Cure radicate de plusieurs Polypes de la Matrice , de la Gorge, et du Nez. Svo. Paris , 1749. M. G. Hcrbiniaux, Traill sur divers Accouchemens laborieux , et sur les polypes de la Matrice, fyc. 2 Tom. 8 vo. Bruzelles, 1782 — 1794. E. Grainger, Medical and Sur- gical tie m arks, including a descript ion of a simple and effectual method of removing polypi from the uterus, tyc. Svo. Lond 1815. Denman’s Plates of a Polypus with an In- version of tht Uterus, and of a Polypus of the Ulerus. fol lSol. F. A. Waller, Annotationes Academii ce 4 to Btrol 1786 W. JYewnham , An Essay an the Symptoms, fyc. of Inversio Uteri , with a History of the successful Extir- pation of that Organ, Svo. Lond. 1818. Pott's Remarks on the Polypus of the Nose. Whate- ly's Two Cases of extraordinary Polypi, Svo. Lond. 1805. John Bell's Principles of Sur- gery, Vol. 3, Part 1. Encyclopedic M6tho- dique, Art. Polype. J. G. Haase, De Narium Morbis Comment. Lips. 1794 — 1797. Lassus, Pathologic Chir. T. I, p. 528 — 538, fyc. Edit. 1809. Callisens Systema CHrurgice Hodier- nce. Vol. 2, p. 169. fyc. J. L. Deschamps, Traite des Maladies dts Fosses JYnsales, et de leur Sinus , Svo. Paris, 18o4. JVauche, des Mai. de V Uterus, Svo. Paris, 1816. Schmeider, Schediasma de Polypo (Esophagi vermiformi rarissimo, fyc. Delitii, 1717. See Halleri Disp. Morb. 7, 595. PORRIGO. TINEA CAPITIS, (called also Ringworm of the Scalp, Scald-head , is, according to Dr. Bateman’s excellent account of the subject, a contagious disease, principally characterized by an eruption cf of the pustules denominated fan and achorcs The achor is defined to be a small acumina- ted pustule, containing a straw-coloured matter, which has the appearance and nearly the consistence of honey, and is succeeded by a thin brown or yellowish scab. The favus is larger, flatter, and not acuminated, and contains a more viscid matter ; its base, which is often irregular, is slightly inflamed : and it is succeeded by a yellow', semi- transparent, and sometimes cellular scab, like a honey-comb ; whence it has obtained its name. (See Bateman's Synopsis of Cutaneous Diseases, p. xxiv. and 159, Edit. 3.) This intelligent physician has noticed sis species of Porrigo, of which my limits will allow me to give only a very abridged de- scription. 1. The Porrigo larvalis, or crusta lactea of authors, begins with an eruption of numerous minute whitish achores, upon a red surface. These pustules soon break, and discharge a viscid fluid, which concretes into thin yel- lowish or greenish scabs. The disease in- creases in extent, and the scabs become thicker and larger, until the forehead and cheeks, even the whole face, excepting the eyelids and nose, become enveloped, as it w ere, in a mask, whence the epithet larvalis. Small patches of the disease sometimes FORRTGO. appear about the uecfc and breast, and on the extremities ; and the ears and scalp are usually affected in the progress of the case. The infant suffers more or less from the itching and irritation When the discharge is copious and acrid, Dr. Bateman recom- mends the part to be washed two or three times a day with tepid milk and water, and the application of the unguentum zinci alone, or mixed with the saturnine cerate. The latter, he says, will be useful for the relief of the excoriation left after the cessation of the discharge. Small doses of the submu- riate oi mercury, cither alone, or in combi- nation with a testaceous powder, wili «lso expedite the cure. If ibe bowels are very irritable, the bydrargyrus cum creta, or the cinereous oxide, may be exhibited instead of the calomel. When the health is good, soda, precipitated sulphur, and the tesiacca, will lessen the local inflammation and dis- charge. When the irritation is removed, and the crusis are dry and falling off, the unguentum bydrarg. nitrat. much diluted, may be used, and the decoction of bark, or the vinum ferri prescribed. 2. Porrigo furfurans begins with an erup- tion of small achores : The excoriation is slight, and the discharge, which is not abundant, soon concretes and falls off in innumerable thin laminated scabs. At irre- gular periods fresh pustules arise, and follow the course of the preceding. The com- plaint is confined to the scalp, which is affected with itching and soreness ; and the hair, which partly (alls off, becomes tbin, less strong, and sometimes of a lighter colour than natural. This species of porrigo occurs principally in adults, and it is sometimes attended with swelling of the glands in the neck. Dr. Bateman observes, that the treatment requires the hair to be closely cut off the scalp. The branny scabs are then to be gently washed .away with some mild soap and water twice a day ; and an oil silk cap should be worn. In the beginning, w'ben the surface is moist, tender, and inflamed, the zinc ointment, or one made w ith 3>j* of the cocculus indicus and 2j. of lard. After- ward, when the scalp is 'dry and free from irritatioo, it may be washed with common soft soap and water: or with a mixture of equal parts of soft soap and unguentum sulphuris. Then the unguentum hydrargyri nit rati, the ung. bydrarg. nitrico oxydi, the tar and sulphur ointments, or the ung. acidi nitrosi of the Edinb. Pharm. may be employ- ed. These last stimulant applications, however, must be left off, if the inflammation and discharge return. 3. Porrigo lupinosa is characterized, ac- cording to Dr. Bateman, by dry, circular, yellowish white scabs, set deeply in the skin, with elevated edges, and a central depression, and somewhat resembling, on the whole, the seeds of lupines. These scabs are formed upon the separate cluster.' of achores, and attain on the scalp the size of a sixpence ; but when on the extremities. they are not more than two lines in diame- ter. In the treatment ol the porrigo lupinosa the scabs arc first to be gently washed oft' with some soap and water, and the scalp is to be shaved, if it be the part affected. When the scabs are difficult of removal, the liquor potassaj, or a weak lotion of muriatic acid may be u-ed for loosening them. Then the ointment of cocculus indicus is to be applied to the red cuticle, and afterward any of the more stimulant ointments above enu- merated 4. Porrigo Scutulata, or ringworm of the Scalp, as Dr Bateman has observed, makes its appearance in separate patches, of an irregular circular shape, upon the scalp, forehead, and neck. It commences with clustersof small, light-yellow pustules, which soon break, and form thin scabs, which, it neglected, become thick and hard. If the scabs are removed, however, the surface un- derneath is left red and shining, but studded with slightly elevated points or pustules. When the disorder is neglected, the patches become confluent, and the whole head affected Where the disease is siti^ed, the hair becomes lighter in its colour, it falls oft', and its roots are destroyed. The porrigo scutulata generally occurs in children three or four years old and upwards, and fre- quently proves exceedingly obstinate. Ac- cording to Dr. Bateman, it seems to origi- nate spontaneously in children of feeble and flabby habit, and who are ill fed, uncleanly, and not sufficiently exercised ; but he thinks that it is chiefly propagated by contagion, i. e. by the actual conveyance of the matter from the diseased to the healthy, as may happen in the frequent contact of the heads of children, the use of the same towels, combs, caps, and hats. While the patches are inflamed and irrita ble, it is necessary to limit the local appli- cations to washing the parts with warm wa- ter. Even shaving the scalp, which must be repeated at intervals of eight or ten days, produces a temporary irritation. Nothing but a light linen cap is now to be worn, and it must be often changed. The disease afterward forms dry scabs, and becomes for a time less irritable ; but a fresh eruption of achores soon follow's, and the inflammation and redness return. In the inflamed states. Dr. Bateman recom- mends the use of ointments, made either with the cocculus indicus, submuriate of mercury, oxide of zinc, superacetate of lead, opium, or tobacco ; or else the infusion of poppy-heads, or tobacco. Where there is an acrimonious discharge, Dr Bateman pre- scribes the zinc, or saturnine ointments, the ung. hydrarg. prascip. calomel ointment, or a lotion of lime-water and calomel. In the less irritable stages, the ung. hv drarg. praecip. the ung. hydrarg. nitrico- oxydi, and especially the ung. hydrarg. nitrat. are often effectual remedies. So arc the ointments of sulphur, tar, hellebore, and turpentine, and lotions of the sulphates of zinc and copper, the oxymuriate of mercury 374 POR PRE 1 have often seen a solution of 3j of the sulphuret of potassa in a pint of lime-water, succeed when most other applications had failed. In the very dry and inert state of the patches, Dr. Bateman has seen the dis- ease removed by a lotion, containing from three to six grains of the nitrate of silver in an ounce of distilled water. The applica- tion of the diluted mineral acids, or of a blister, has also been known to put a perma- nent stoppage to the morbid action. In general, no local application agrees well, if long continued, and it is necessary to have several, which must be alternately employed. The cure may often be expedited by cin- chona, chalybeate, and alterative medi- cines; and attention must be paid to the patient’s diet, exercise, &,c. 5. Porrigo decalvans consists in bald patches, surrounded by hair which is as thick as usual It is not known whether any eruption of minute achores actually precedes the detachment of the hair. Dr. Bateman remarks, that if the scalp is regular^T shaved, and some stimulating linimeAf be applied to it, this obstinate affection may at length be overcome, and the hair will regain its usual strength and colour. Two drams of oil of mace, in three or four ounces of alcohol, are said to make an excellent liniment. 6. Porrigo favosa consists of an irruption of the large, soft, straw-coloured flattened pustules, denominated favi, which may occur on any part of the body ; but most commonly spread from the scalp, especially behind the ears, to the face, or from the lips and chin to the scalp. They are attended with considerable itching, and are most fre- quently seen in children from six months to four years of age, though adults are also often affected. The pustules pour out a viscid matter, which concretes into greenish or yellowish semi-transparent scabs. When the hair and moist scabs are matted together, pediculi are often generated in great num- bers, and aggravate the itching and irrita- tion. If the disease be allowed to increase, the scabs are thickened into irregular masses, not unlike honey comb ; and considerable ulcerations sometimes form, especially when the heel and toes, or other parts of the lower extremities, are affected. The ulcerating blotches are generally soon followed by irri- tation and swelling of the lymphatic glands, which sometimes slowly suppurate, lhe contact of the discharge inoculates the dis- ease ; thus, in young children, the breast is inoculated by the chin ; and the arm and breast of the nurse may be infected in the same way ; though adults do not take the complaint so quickly as children. The porrigo favosa requires the same alteratives, internally, as the porrigo larva- lis. The diet should consist of milk, pud- dings, and a little plain animal food. When the habit is bad, and the glands swelled, bark, chalybeates, and a solution of the mu- riate of barytes, are proper. As local applications, Dr Kateman pre- fers the unguentum zinci, or the ung. by- drarg. praecip. mixed with this or the satur- nine ointment, especially when the discharge is copious. He also speaks favourably of the ung. hydrarg. nitrat. the strength of which is to be diminished by an addition of simple cerate, according to the degree of irritation present. For the preceding particulars I am indebt- ed to Dr. Bateman’s valuable Synopsis of Cutaneous Diseases, where the reader, de- sirous of additional information respecting porrigo, will be amply gratified. POTASS* ARSENICATA. Kali Arstni- catum. Arsenias Kali. Oxydi albi arseni- ci, potassa? nitratis sing Crucibulo am- plo igne candenti injice nitrum, et liquefacto adde gradatim arsenicum in frustulis donee vapores nitrosi oriri eessaverint. Solve ma- teriam in aqua? distillatae ft>iv. et post ido- neara evaporationem sepoue ut fiant crys- talli. These crystals may be given in the dose of one-tenth of a grain, thrice a day. ( Pharm . Saadi Barthol. 1799.) Justamond strongly recommended the internal exhibi- tion of arsenic in cases of cancer. (See Cancer.) POTASSiE CARBONAS. Two drams of this medicine have been given, as a lithon- triptic, at St. Bartholomew’s Hospital, in a pint of distilled water, twice a day. POTASSA FUSA. Caustic Potash. This is one of the most useful caustics for de- stroying fungi, making issues in cases of diseased vertebrae, white swellings, &.C.; and it is recommended be used in a par- ticular manner, by Mr. Whately, for the cure of strictures in the urethra. When surgeons prefer opening buboes, or any other ab- scesses, with caustic, the caustic potassa is very commonly employed. When surgeons used to cure hydroceles, by destroying a part of the scrotum and tunica vaginalis with caustic, the potassa fusa, either alone or mixed with quicklime, was made use of. (See Vertebra, Urethra , Strictures of, fyc.) POTASSiE SULPHURETUM. Sulphu- ret of Potash, Liver of Sulphur. Two drams, dissolved in a pint of lime or distilled water, make an excellent lotion for the cure ot porrigo. Many other cutaneous affections yield also to the same remedy. When arse- nic has been swallowed as a poison, twenty grains of the sulphate of zinc may be given as an emetic of the quickest operation ; and, after keeping up the vomiting by drinking warm water, and, what is better, sweet oil, some authors recommend making the pa- tient drink as much as possible of a solution of the sulphuret of potash. PREGNA1NCY is set down by some wri- ters as preventive of the union of broken bones ; but many exceptions to the remark present themselves in practice ; for I have attended myself a female, six months gone with child, who broke both bones of her leg, yet they grew together again in the usual time. (See Fractures.) Pregnant wo- men also frequently bear operations much better than might be expected. Thus M. JNicod bus recently published a successful PROSTATE GLAAD. amputation of the left leg during pregnancy, in a case where the right tendo Achillis was also ruptured. Both the wound, and the broken tendon, united very well. (See Annuaire Med. Chir. des Hdpitaux de Paris, p. 509 4 to. Paris, 1819.) PROBANG A long slender bit of whale- bone, with a bit of sponge at its extremity, intended for the examination of the oesopha- gus, or the removal of obstructions in it. PROCIDENTIA. Prolapsus. A falling down of any part. (See Anus, Prolapsus of. Uterus, Prolapsus of, fyc.) ^PROSTATE GLAjND, DISEASES OF. It is an observation, made by Mr. Hunter, that the use of this gland is not sufficiently known to enable us to judge of the bad con- sequences of its diseased state, abstracted from swelling. Its situation (says he) is such, that the bad effects of its being swelled must be evident, as it may be said to make a part of the canal of the urethra, and there- fore, when it is so diseased that its shape and size are altered, it must obstruct the passage of the urine. (On the Venereal Disease , p. 169.) A swelling of the prostate gland, however, may be of very different kinds : thus it may depend either upon common inflammation of the part, abscesses, calculi formed within its substance, a varicose en- largement of its vessels, or a scirrhous chro- nic induration, (.->ee (Euvres Chir. de De- sault par Bichat, T. 3, p. 220.) Modern anatomists describe the prostate gland as not being itself a very sensible part, and hence it is more subject to chronic than acute disease, to which, however, it is also liable. We have the authority of Desault, Hunter, and Dr. Baillie, for setting it down as subject to scrofula. The latter physician, after stating that he has seen a common abscess situated in it, adds, that it is also subject to scrofulous disease, as, on cutting into it, he has met with the same white curdy matter which is formed in a scrofu- lous absorbent gland ; he has likewise forced out of its duct scrofulous pus. (Morbid Anatomy, fyc.) Mr. Lloyd states, that he has also met with fleshy enlargements of the gland, in the substance of which several small ab- scesses were formed, containing “ a com- plete scrofulous matter. ' He has also known enormous enlargements of this gland hap- pen in young men who were labouring, at the same time, under other scrofulous dis- ease. Other instances of supposed scrofu- lous svvellings of the same part in young patients are likewise cited by this author, one of w hich is particularly remarkable, as in it the gland was found after death to be of the size of a child’s head, though its na- tural consistence was not much changed. (On the Nature and Treatment of Scrofula, p. 107.) Other chronic, or as they are more often called, scirrhous enlargements of the prostate gland, rarely occur in subjects un- der the age of fifty. To these cases I shall presently return. Like every other part of the body, the prostate gland is .sometimes, but not often. the seat of common phlegmonous inflamma- tion Mr. Wilson has known two or three instances of this kind take place soon after puberty ; one case was from a fall ; the others arose without any assignable cause, (On the Male Urinary and Genital Organs, p. 327.) There is also a phlegmonous swell- ing of the prostate gland, sometimes an effect of strictures, as will be presently no- ticed. \s Desault observes, the retention of urine, arising from such a cause, comes on very suddenly and rapidly increases. The patient at first complains of a sense of heat and weight about the perinaeum ; and, soon afterward, of a continual throbbing pain about the neck of the bladder. The pain is severely increased when the patient goes to stool ; and there is tenesmus, and frequent inclination to make w r ater. How- ever, according to Mr. Wilson, the desire to evacuate the urine is here less constant than in cases where the inner membrane of the bladder is inflamed. (Vol. cit.p. 327.) The patient feels also as if a large mass of excre- ment filled the extremity of the rectum, and were ready to come out. If a finger oe in- troduced within the rectum, the swelling of the gland is plainly distinguishable; and, according to J. L. Hetit, the projection of the prostate gland in the bowel makes a corresponding hollow groove along the concave side of the excrement, as may be noticed, when what is voided is hard. How- ever, Bichat conceiv es, that such an appear- ance must generally be obliterated as the excrement is passing through the sphincter. When the patient attempts to make water, it is a long while befor, the first drops come out, and asstraining has the effect of pro- pelling the swelled prostate more against the neck of the bladder, it only increases the difficulty, and no urine will come out until such efforts are discontinued. The more violent the inflammation is, the smaller is the stream of urine, and the more acute the pain felt during its expulsion. Accord- ing to Desault, it is likewise particularly re- markable in such cases, that if an attempt, be made to introduce a catheter, the instru- ment passes without the least resistance as far as se parts with psoric matter. ( Lelire von den Augenkr. B. 1 ,p. 566.) Weller not only adopts the same notion, but makes an ad- dition to it, by extending the tern^flriso to cases, in which the eyelids are affected with psoriasis, porrigo, and impetigines. (Ma- nual of the Diseases of the Eye, Vol. 2, p. 264.) By psoropktkalmy, the late Mr. Ware meant a case, in which the inflammation of the eyelids is attended with an ulceration of their edges, upon which a glutinous matter lodges, in crusts, and becomes hard, so that, in sleep, when they have been long in con- tact, they become so adherent, that they cannot be separated without pain. He has remarked, that “ the ulceration in the pso- rophthalmy is usually confined to the edges of the eyelids ; but sometimes it is seen to 'extend over their whole external surface, and even to excoriate the greater part of the cheek. In cases of the latter kind, the inflammation which accompanies, has often much the appearance of an erysipelas, and will receive most relief from the cooling ap- plications. The use of the citrine ointment, which will hereafter be recommended, must in such instances, be deferred until the irritability of the skin is in a good degree abated. il This disorder is also sometimes attend- ed with ^ contraction of the skin of the lower eyelid ; in consequence of which that lid is drawn down, and. the inner part turn- ed outward, so as to form a red, fleshy, and most disagreeable appearance, called ectro- pium. Whenever this happens, it proves the complaint to be of the most obstinate na- ture ; though it is generally, removed by the cure of the psorophthalmy, whichristhe oc- casion of it.” ( Remarks on Ophthalmy, fyc. p. 112.) Mr. Ware recommended, for the cure of this disease, the unguentum hydrar- gyri nitrati. This is to be melted into an oil, and rubbed with the end of the fore-fin- ger, or the point of a small pencil-brush, into the edges of the affected eyelids, once every night, on going to bed. A plaster of ceratum album is then put over the eyelids to keep them from adhering together. If they should still adhere in the morning, they are to be cleaned with milk and butter, well mixed together. In a few cases, it is neces- sary to touch the ulcers, formed on the edge ot the eyelid, after the small-pox, with the argentum nitraturn. When the globe of the eye is inflamed, the vinous tincture of opium is applied, as directed in the article Ophthalmy. In scrofulous subjects, altera- tive medicines ; an issue, or perpetual blis- ter; and attention to diet, &c. are proper. (See Ware on Ophthalmy , <^c.) In the treatment of psorophthalmy, Beer lays considerable stress upon the necessity ot cleanliness. The itehy places he directs to be frequently washed with a tepid infu- c ton of scordiuiri, and afterward well dried. When the uneasiness and tension of the skin are thus quite removed, Beer adds to the preceding infusion some of the sulphu- ret of potash, the proportion being at first small, and gradually increased. This plan is to be followed, until the ulcerations dry and the scabs fall off of themselves, leaving the subjacent skin yet red and sensible, and sometimes moist ; in this state, a small bit of the annexed salve may be smeared with a. camel-hair pencil along the edges of the eyelids, and upon the affected points of the. skin : R. Butyri recentis insulsi, ^ss. Cu- pri Sulphatis, gr. x. Camphoree, gr. iv. Tu tise ptt. gr. vj. Misce. If the disease prove obstinate, Beer recommends Hufeland’s salve, wbich consists of equal parts of fresh, butter, yellow wax, and the pulv. hydrarg. nitneo-oxydi rubr. ; and, in still more inve- terate cases, Janin’s eye salve, which, he says, must rarely be used oftener, than every other day. In the psorophthalmy, conjectured by Beer to depend upon the sudden cure of the itch, he-states, that in- ternal medicines are necessary, as antimo- nials, joined with sulphur and camphor. He also praises sulphur baths, and irrita- ting the part of the skin where the itch has receded, by th$ application of antimo- nial ointment ; or /if such part should be very far from the eyes, he advises such ointment to be rubbed on the skin behind the ears. Attention to diet is particularly enjoined, and eating pork, lard, and sub- stances difficult of digestion, is prohibited, (B. 1. p. 569, fyc.) (tlim. of sis of the Diseases of ike Eye , p. 343.) In a modern work, Professor Maunoir of Geneva, has published a very successful case, in which an artificial pupil was former^ and a caseous cataract extracted. u I ope- rated, (says M. Maunoir) on the right eye in the following manner. The patient being seated on a chair, and having the head in- clined upon a cushion, I placed myself be- hind him, and with the fore-iingei of the left hand, confining the upper eyelid, 'whilst an assistant depressed i be lower. I made with the right hand a semicircular incision in t lie lower and external part of the cornea This incision occupied a full third of the circumference of the membrane. On reopening th Having very easily passed a small probe into the orifices, a matter similar to white of egg, made its escape. A small leaden probe was passed into each opening, and two days afterward, the sacs were emptied again, and two pieces of lead, somewhat larger, introduced. The man was advised to take out the pieces of lead every morning, empty the swelling, and then replace them. In a fortnight, the openings having been kept continually dilated, had no tendency to close ; the saliva did not accumulate, and the ranulae never appeared again. In certain cases, the above means are quite inadequate, and the tumour must be totally extirpated. Boinet has related to the French academy, a case in which the swelling not only filled the whole mouth, but one half of the tumour projected out, and a cure could only be accomplished in the latter manner. The two upper incisor teeth on the left side, were lodged in a depression observable there; and the canine tooth, of the same side, forced outward by the mass of the disease, had pierced the lip near its commis- sure. A fluid resembling mucus, flowed from a narrow aperture at the lower part of the swelling. The tongue could not be seen, so much was it pushed backward, and for some time, the patient had only subsisted on liquid food, which he was first obliged to convey to the back t>f the throat with some mechanical contrivance. The tour incisor teeth, two canine, and first grinders of the lower jaw, had been pushed out of their sockets, by the pressure of the swelling. The patient’s aspect was alarming, and he was threatened with suffocation. Extirpa- tion was deemed necessary, and it was per- formed with all the caution which the situa- tion of the tumour demanded. The large cavity thus occasioned was filled with lint. The lower jaw being diseased, Boinet scra- ped some of its surface oft', and covered the places with lint, either dry or dipped in spirit of wine. Some exfoliations followed, and the fungous granulations which grew were re pressed with proper applications. In three RECTUM. months, the parts were healed in so regular a manner, that the motion of the tongue was not in the least obstructed, and no change continued, except the alieration of the voice, occasioned by the loss ol teeth. This case is very interesting and proves how much may be hoped for in difficult cases, from prudent and judicious measures. (S»e E ncy- clop6die M6tkodique,Art. Grenouillette. M6m de V Acad, de Chirurgie , T. 3, Sabatier. Me- decine Ophatoire , T. 2, p. 19, fyc. Ed. 2. Callisen , Systems Chirurgicc Hodiernce , Vol. 2, p. 108, ty-c. II af nice, 1800. Lassus, Pa- thologic Chir. T. 1, p. 402, fyc. 8 vo Paris , 1809. Richter, Anfangsgr. der Wundarzn. B. 4, Kap. 1, Gottingen, 1800. J J. Stahl , et J. F. E. de Schoenerben de Ranula, sub lin- gud, speciali cum casu , Erford. 1 i 34.) RECLI NATION. A term much employ- ed abroad, to denote the operation of turn- ing a cataract, so as to change the position of its anterior and posterior surfaces. (See Cataract.) RECTUM. Many cases in which this bowel is more or less concerned, are treated of elsewhere in this Dictionary, and therefore it will only be necessary for me here to re- fer to them, and then notice some diseases of the part, which are not considered in other articles. For an account of piles, he- morrhoidal excrescence, and other tumours of Ihe rectum, see Hemorrhoids; and for that of prolapsus ani, fistuia in ano, and im- perforate anus, see Anus. Under the head of divine Concretions. I have noticed the dan- gerous obstruction of this bowel by masses of indurated matter. In the article Lylhoto- my, the mode oi cutting through the rectum into the bladder, for the purpose of extract- ing a calculus irorn the latter organ, is ex- plained ; and if the reader refer to Bladder, fie will there find a description of the method of tapping it from the rectum. Scirrhus, or stricture of the rectum, some- times called the scirrho-coniracted rectum, and sometimes cancer, especially when the case is inveterate and in a state of ulcera- tion, is a disease which has received much elucidation from the writings of Desault, Sir Everard Home, Dr. Sherwin, and Mr. Cope- land. In the various descriptions given of the complaint by these and other writers, one great point of difference is remarkable, viz. that some of them represent the case as always of an incurable pature, while others consider it as admitting of relief, at least when it has not made considerable progress, and the parts are free from ulceration. Ac- cording to Desault, scirrhus of the rectum is not uncommon at an advanced period of life, and the disease is said to afflict women more frequently than men, as from a table kept at the Hotel Dieu, it appeared that ten cases out of eleven occurred in females, if it were not for the fact, that Desault some- times effected a cure of the disease in its early stage, I should venture to conclude, that his observations apply entirely to the true scirrhus, or cancer of the rectum, which 1 believe rarely or never occurs in young patients, but as Desault states, is not very unfrequent in elderly persons. My friend, Mr. Copeland, in his practical remarks, does not v confine himself to really scirrhus and cancerous affections, but comprehends stric tures of the rectum from a variety of causes; and this accounts for his statement, that the disease “ attacks people of almost all ages ; but is most common about the middle age.” However, he agrees with D**sauU, that wo - men are more frequently affected th .n men. He admits that it is sometimes cancerous, though not so often as is generally imagined, the mere induration not being an unequivocal, proof of it. When the disease is really can- cer, it is usually attended with more severe pain, darting through the pelvis to the blad- der and the groin. The countenance is of a sallow leaden cast. (Copeland on the prin- cipal Diseases of the Rectum and Anus, p. 15 —17. Sometimes the disease extends over a considerable length of the gut, but is gene- rally more circumscribed. The coats of the bowel become much thicker and harder than natural. The muscular is subdivided by membranous septa, and the internal coat is sometimes formed into hard, irregular folds. The surface of the inner membrane is occa- sionally ulcerated, so as to form a cancerous disease. Every vestige of the natural struc- ture is sometimes lost, and the gut is changed into a gristly substance. The cavity of the bowel is always rendered narrow at the scir- rhous part, and is sometimes almost oblitera- ted. When Ihe passage through the gut is very much obstructed, the bowel is always a good deal enlarged just above the stoppage or stricture, from the accumulation of the feces there. As the disease advances, adhe- sions form between the rectum and adjacent parts, and ulcerations produce communica- tions between them. As the disease at first is not very painful, it is usually not much noticed till somewhat advanced. The patient is habitually cos- tive, and usually voids his stools with a little difficulty. In time, a good deal of pain is felt in the part affecied, especially at stool, after which some relief is experienced. “ As the gut continues to decrease in diameter (says Mr. Copeland,) the efforts to expel the feces become more violent, and the conse- quent progress of the .disease more rapid. The stools, which have been long evacuated with difficulty, become contracted in size, appearing like earth- worms in their form, or small pellets;” and if the finger be intro- duced into the rectum, “ the gut will be found either obstructed with small tubercles, or intersected with membranous filaments ; or else the introduction of the finger will be opposed by a hard ring of a cartilaginous feel, composed of the diseased inner mem- brane of the intestines.” These states, as Mr. Copeland observes, are very different from the regular tumour on t ;, c anterior part of the rectum, occasioned by an en- largement of the prostate gland ; a case apt to be suspected. u As the disease advan- ces (says the same author,) the feces become more fluid, and there is a thin saneous div KECTUM 399 charge from the anus, accompanied with tenesmus.” According to Desault, pus and blood may sometimes be noticed with the excrement, particularly when the disease has advanced to the ulcerated state. The patient at length becomes sallow, frequent eructations of air from the bowels, as Mr. Copeland observes, torment the patient, and render his life miserable ; the constitution suffers, and dissolution follows. Severe tenesmus attends the whole course of the disease. (CEuvres Chir. par Bichat , T 2.) Sometimes a small fistulous orifice at the verge of the anus communicates with the inferior portion of the diseased part. Such a fistula, in a case recorded by Sir Everard Home, was half an inch in length. ( Obs . on Cancer , p. 133.) Desault has often seen the disease form a communication between the rectum and vagina, and the feces passed through the latter part. In the latter stage of the afflic- tion, the rectum, bladder, vagina, uterus, and adjacent parts, are all involved in one common ulceration. When the disease has attained the ulcera- ted state, it is probably always incurable. Palliatives can only now be resorted to, such as anodyne and emollient glysters, the warm bath, foe. with the exhibition of me- dicines like opium, cicuta, uva ursi, foe. Claudinus applied his remedies to the inside of the bow r el, by means of tents, and did not employ the latter as a mode of curing the disease when less advanced. Valsalva in- troduced a cannula, pierced with numerous holes, and then made his patient get into a bath, so as to let, the fluid enter the intestine. Numerous practitioners, among whom is Morgagni, made mercurials the base of their treatment, from a supposition that the com- plaint was of venereal origin. J believe the latter opinion is at present entirely abandon- ed by all the most judicious surgeons in England, and this, whether mercury ever prove useful or not. When the disease is not .attended with ulceration, the contraction and thicken- ing of the gut may be diminished by in- troducing bougies, keeping them for a certain time, every day, so introduced, and increasing their size gradually. The pressure of these instruments seems to lessen the disease, and stop its progress ; a proof that its nature differs from that of a common malignant scirrhus. Desault used to employ long tents made of lint, smeared with cerate, and passed into the bowel by means of a probe with a forked end. Their size was gradually increased, so as to keep up the compression, to which, it was con- ceived, all the good was owing. Their length was also augmented by degrees. At first, fresh ones were introduced twice a day. When any hardnesses were situated on the outside of the anus, Desault cured them on the same principle, viz. by making pressure on them with compresses and a bandage. In this manner he effected the cure of a seirrho-cpntracted rectum. The patient was taught to pass occasionally the tents, without assistance, in order to pre- vent a relapse. Instead of tents, modern surgeons employ bougies for the dilatation of strictures in the rectum. When from habitual costiveness, the altered figure of the stools, and other circumstances, there is reason to suspect organic obstruction to the passage of the fee ed, and this suspicion is confirmed by an examination of the rectum with the finger, a the first object of the surgeon (says Mr. Copeiand) should be an enlargement of the obstructed part, by the introduction of a bougie. This should be of such a size as to pass, when well lubricated with oil, without much difficulty or pain. Sometimes, when the disease has been of long continuance, it will be necessary to begin even with a large- sized urethra bougie, or one of the same size as those which are made for a stricture of the oesophagus, and of a length that is likely to pass beyond the end of the stric- ture, that is, about six, or seven, or eight inches. But I think it of consequence to use a bougie, at first, which is rather too small than too large.” (P. 29.) When it has remained for half an hour, or more, it is to be removed, and passed again the next day, the same sized bougie being continued for several days. In the introduction of the bougie, Mr. Copeland cautions the practi- tioner not to mistake the projection of the sacrum for a stricture of the gut ; a mistake which, he says, has often been made, and, as I believe, too often wilfully, and from motives of imposition. Mr. Copeland fur- ther advises the bowels to be ke*pt constantly lax, by the use of castor oil, or electuary of senna, during the whole of the treatment. (P. 30.) Whatever be the nature of the stricture, whether it be that kind in which the rectum is obstructed by tubercles, by membranous filaments intersecting its canal, (which two species, Mr. Copeland says, are the most easily relieved) or whether it be the indurated stricture, from a thickening of the coats of the intestine, this local treat- ment is equally necessary. The pian is to be persisted in until a full-sized bougie will readily pass, and even after all symptoms have disappeared it is recommended to in- troduce the bou ie, and withdraw it again once every two or three days, for some time, in order to prevent a relapse. The in- durated annular stricture, which long resists the bougie, Mr. Copeland sometimes divides with a probe-pointed curved bistoury on the side which is contiguous to the os sacrum ; and he has frequently seen the late Mr. Ford perform the same operation. (P. 34.) When the disease is either combined with venereal symptoms, or there is any reason for sus- pecting it to be itself “ the solitary symp- tom” of lues. Mr. Copeland joins Desauk in recommending a trial of the effect of mercury, in conjunction with bougies. (P. 44.) The formation of abscesses, he re- marks, is very frequent in the advanced stages of the disease, and he has often seen the common operation for fistuladone under such circumstances tvithout success. (P.3 5 • HICKEXS. 'IWU When uny stoppage of urine occurs in the advanced stage of the disease, Mr. Cope- land advises surgeons not to use the catheter hastily. ( P . 39.) And, in the event of great pain and irritation in the rectum, he has seen the greatest benefit derived from the local application of opium either in a glys- ter, or by the introduction of one or two grains of the medicine within the anus. He also speaks favourably of the effects of the warm bath, and fomentations, in giving temporary relief ; and he has also exhibited in these cases the pil extracti conii cum hydrarg. submur. with considerable advan- tage. A fatal case of mortification of the rec- tum is detailed by Larrey. ( Parisian Chi- rurgical Journal, Vol. 2, p. 398, <^c. See J. L. Petit , CEuvres Posthum. T. 2. Dr. Sher- win on the schirrho-conlraded rectum, in Mem. of the London Medical Society , Vol. 2. Sir Everard Home , Obs. on Cancer , p. 129, fyc. S vo. Lond. 1805. L. F. J. Duchadoz , De Prodostenia , seu de Morbosis Intestini Recti Angustiis, Monsp. 1771. C. G. Siebold, De Morbis Intestini Recti Baillie's Morbid Anato- my, p. 1116. CEuvres Chir. de Desault par Bichat , T. 2, p. 422. Observations on the principal Diseases of the Rectum , fyc. by T. Copeland , 1814. W. White, Observations on the Contracted Intestinum Rectum, 8 vo. Bath, 1812.) RESOLUTION. (from resolvo.) The subsidence of inflammation without any abscess, ulceration, mortification, &c. Also the dispersion of swellings, indurations, &c. RETENTION OF URINE. See Urine, Retention of. RETROVERSIO UTERI, a turning back- ward of the womb. See Uterus , Retrover- sion of. RICKETS. (Rachitis.) Is mostly met with in young children ; seldom in adults. Mo- rand, however, (Acad, des Sciences, 1753.) mentions an instance, in which an adult became affected. The disease it is said, may even take place in the foetus in utero ; but the most common period of its com- mencement is in children, between the ages of seven or eight months, and two years. Hence, as Mr. Wilson observes, its origin has frequently been imputed to the effects of dentition. He adds, that he has often known it to make its appearance after this time, and that it not unfrequently attacks the spine a little while before puberty, and may do so even later. (On the Struc- ture and Physiology of the Skeleton, fyc. p. 162.) Pine! has given a description of the skeleton of a rickety foetus. (Fourcroy’s Journal.) The disease seems to consist of a want of due firmness in the bone9, in con- sequence of a deficiency in the phosphate of lime in their structure. The causes of the affection are involved in great obscurity. Authors have referred them to scrofula, scurvy, lues venerea, difficult dentition, &c. ; nnd Richerand still firmly believes, that rachitis is only one of the effects of scrofula in its worst forms. (JVosographie Chir. T. 3. v ■ 148, Edit.. 4.) But these are merely conjectures, which will not bear a rigorous investigation. Professor Boyer, in particu- lar, has well exposed their invalidity. Traitd des Mai. Chir. T. 3, p. 611.) Rickety subjects are often at the same time scrofulous ; and this is, probably, the only reason for scrofula being accounted a cause of the other affection. The particu- lar appearances of rickety children we need not detail, as every one is familiarly acquainted with them : such children are usually of a bad, weak constitution, and their limbs and bones become bent in direc- tions determined by the action of the mus- cles, and the weight and pressure which they have to sustain. When the affection is very general, the spine becomes shorter, and is curved in various directions ; the breast becomes deformed not only in con- sequence of the curvature of the spine, but by the depression of the ribs, and projection of the sternum. The bones of the pelvis fall inwards, and the os pubis generally ap- proaches the sacrum. The latter circum- stance is one of the causes of difficult parturition. The clavicles become more bent and prominent forward ; the os humeri is distorted outward ; the lower ends of the radius and ulna are twisted in the same direction ; the thighs are curved forwards or outwards ; the knees fall inwards ; the spine and front surface of the tibia become convex ; and the feet are thrown out- wards. According to the observations of Mr. Stanley, when the tibia and fibula become curved, they sometimes “ acquire increased breadth in the direction of the curve, losing a proportionate degree of thickness in the opposite direction. Hence the bones be- come, as it were, newly modelled, passing from the cylindrical into the flattened form. This would seem to be designed for the pur- pose of enabling them to support more efficiently the weight of the body, since by this alteration they acquire increased breadth and power of resistance in that direction, where the greatest strength is required. I have never noticed (says Mr. Stanley) any expansion in the articular ends of rickety bones, as is mentioned by some authors, I should therefore feel inclined to believe, that there has existed only the appearance of such a phenomenon, the ends of the bones having appeared swollen, in conse- quence of the emaciation of the surround- ing soft parts. (See Med. Chir. Trans. Vol. 7, p. 402— 405.) When the thoracic viscera are considera- bly oppressed by the alteration in the figure of the chest, produced by rickets, the dis- ease may bring on fatal consequences. Boyer has thus described the appearances of rickety bones : They are lighter than natural, and of a red, or brown colour. They are penetrated by many enlarged blood-vessels, being porous, and, as it were, spongy, soft, and compressible. They are moistened by a kind of sanies, which may be pressed out of their texture, as out ©f ai sponge, or rather a macerated hide after it has been tanned. The walls of the medullary cylinder of the great bones of the extremi- ties are very thin, while the bones of the skull are considerably increased in thickness, and become spongy and reticular. All the af- fected bones, especially the long ones, ac- quire a remarkable suppleness ; but if they are bent beyond a certain point they break, &c. Instead of being filled with medulla, the medullary cavity of the long bones con- tains only a reddish serum, totally devoid of the fat oily nature of the other secretion in the natural state. \See Boyer , Trait6 des Maladies Chir. T. 3, p. 619.) The consis- tence of several rickety bones, examined by Mr. Stanley, was nearly that of common cartilage. They presented throughout an areolated texture, and the cells were in some parts large, and contained a brownish gela- tinous substance. This gentleman did not find the periosteum thickened, as Bichat has described it. ( Analomie Generate , T. 3.) The investigations of Mr. Stanley have also discovered, that, in the process by which rickety bones acquire strength and solidity, there is always an undeviating regularity in the situation, extent, and direction of the deposited earthy matter. “ Thus it is obvi- ous (says this gentleman) that, in the curved bone, the part where there is the greatest need of strength, to prevent its further yielding, is in the middle of its concavity, or in other words, in the line of its interior curve; and it is just in this situation, that strength and compactness will be first im- parted to the bone by the deposition of phos- phate of lime. It will be further found, that the greatest resistance being wanted at this part, the walls are accordingly rendered thicker here than elsewhere, and the degree to which this excess in thickness is carried, bears an exact ratio to the degree of curva- ture, which the bone has undergone.” Mr. Stanley’s observations also prove, that the bony fibres are arranged obliquely across the axis of the bone, in a direction calcula- ted to augment its strength. Lastly, we learn from the same authority, that if a long bone, like the tibia, be very much bent, while it has to support a great superincum- bent weight, the deposition of the bony mat- ter may not be confined to the thickening of the walls of the concave side, but may extend across the medullary cavity, render- ing the bone here perfectly solid, and there- by greatly strengthened. (See Obs. on the Condition of the Bones in Rickets , fyr. by E. Stanley, in Medico- Chir. Trans. Vol. 7, y. 404, et seq.) We learn from Mr. Wilson, that for many 3 r ears past, he has also exhibited in his lec- tures preparations, illustrating the fact of the abundant deposition of osseous matter, “ when the bones begin to recover from the disease, at the part where it is most wanted, viz. on the inner part of the concave surface of their curve.” (On the Skeleton , fyc. p. 167.) Many very rickety and deformed infants improve as they grow up, and acquire strertgtb. The defermit v of their limbs snori- 7 ' >r Jr taneously diminishes, and the bones gain a proper degree of firmness, a due quantity of the phosphate of lime being deposited in their texture. it is a question, whether the restoration of the proper figure of the bones can be pro moled by the constant pressure of bandages, and mechanical contrivances, sold in the shops. Some authors contend, that in very young children machines are useless, as the confinement and inactivity of the muscles, necessarily occasioned by such contrivances, must increase the general debility, and con- sequently the disease. Notwithstanding the praises which have been bestowed on those mechanical means by their inventors, and even by respectable authors, says Boyer, they are not now used by any enlightened judicious practitioners, it being generally agreed, that it is best to leave to nature alone, aided by good medi- cal treatment, the duly of rectifying bones deformed by the rickets. ( Trait e des Mai. Chir. T. 3 p. 627.) Delpech expresses him- self still more strongly against the employ- ment of machinery. (See Precis Elemen- tal re des Maladies Chir. T. 3, p. 740, fyc.) However, these opinions against mechani- cal contrivances for the improvement of rickety bones, are not meant to apply to ma- chines for rectifying distortions of the fool. In such cases, the malformation does not de- pend on constitutional causes, and mechani- cal means will do whatever is possible. No medicine is known, which possesses any direct efficacy in cases of rickets. To- nics are indicated, and should be employed. The state of the bowels must in particular be attended to. The disease appearing to consist in a deficiency of lime in the bones, proposals have been made to exhibit inter- nally the phosphate of lime ; but this chy mical project has had no success. (See Bon homme’s Memoir on Rachitis , in Duncanhst Annals for 1797. Several circumstances considered by M.‘ Wilson, tend to prove, that this scheme could present no chance of benefit, because there is no proof of a deficiency of lime in the system, though the arteries of the bones do not deposit it in the natural degree. (See Wilson on the Skeleton , fyc. p. 163, fyc.) More good is generally effected by keep- ing children in healthy situations, and in a salubrious air, than by any medicines what- ever. Light, wholesome, nutritious, easily digestible food; cold bathing; good nur- sing; regular gentle exercise; or airings in a carriage ; the use of the flesh-brush, fee. are also highly serviceable. The constitu- tional treatment of rickets belongs more properly to the physician than the surgeon ; and it is not necessary to introduce more of the subject into a Dictionary expressly al- lotted to surgery. See the article Mol, lilies Ossium , and con- sult particularly Buchner de Rachitide perfec- ta et imperfecta Disput. Argent. 1754. G iis- son, de Rachiiide , sive,. morbo puerili. Ludg. Batav. 1671. Bonhomme’s Mem. on Rachitis, in Duncan's Medical Annals for 1797. Riche- -SAR SAR (A«2 vmd, JVosographie Chir. T. 3, p. 142. fyc. Edit. 4. LcvMM, in Mem. de Physiologic et de Chirurgie , par Scarpa, fyc. Boyer, Trailt des Maladies Chir. T. 3, p. 607, fyc. Stan- ley's Ohs. in Med. Chir. Trans. Vol. 7,p 404 Delpech Precis EUmentaire des Mala ies Chir. T. 3, p. 749, fyc. Tmka de Krzowltz, Jlistoria Rachitidis, 8 vo. Vindob. 1787. R. Hamilton Remarks on Scrofulous Affections, fyc. &ve. Lond. 1791. A. Portal, Obs. sur la Nature et sur le Trailemenl du Rachilisme, ou des Courbures de la colonne Vertebrate et de celles des Extremites. 8 vo. Paris , 1797. And particularly, Lectures on the Structure and Physiology of the Skeleton, Diseases of Bones, fyc. by James Wilson, p. 159, fyc. 8 vo. Lond. 1820. RINGWORM. See Herpes. RUPTURE. A protrusion of the abJomi nal viscera. See Hernia. s. ^4 \BINA. (said to be named from the Sa- k 3 bines, whose priests used it in their re- ligious ceremonies.) Savine. The use of the leaves of this plant, in forming the active ingredient in the ointment commonly pre- ferred for keeping open blisters, has been explained in the article Blisters. The other chief surgical use of savine, is as a stimula- ting application for destroying wart?, and other excrescences. For the latter purpose, it is generally powdered, and mixed with an equal proportion of siibacetate of copper. The same powder is also sometimes employ- ed by surgeons for maintaining the hollows into which peas are inserted in issues. The best plan is, first to wet the peas, then roll them in the powder, and put them in this state on the issue. But when the whole sur- face of the issue has risen high, above the level of the skin, the powder must be sprin- kled all over the sore, so as to produce an absorption of the high granulations. — indeed, even in this manner, a good cavity often cannot be obtained ; and it becomes neces- sary to destroy the surface of the issue, by rubbing it with caustic potassa, or potassa cum caice. SACCHARUM SATURNI. Sugar of Read. Cerussa Acetata. Acetate of Lead. This is very extensively used in surgery, chiefly as a local application to inflamed parts, and in the form of a lotion. See In- domination, Collyrium, Lotio, Gonorrhoea , Ophthaimy, and numerous other articles of tins Dictionary, for an explanation of (he uses of acetate of lead. SAL-AMMONIAC. Ammonia Muriata. Muriate of Ammonia. Employed a good deal by surgeons, as an ingredient in discu- tient lotions. See Lolio Ammon. Mur. SALIVARY FISTULAS. See Parotid Duct. SANIES. (Latin ) A thin, serous, fetid matter, discharged from fistulm, unhealthy sores, fee. It is sometimes tinged with blood. SAI'O TE RE B I N T H I N 7E . ( Starkey's Soap.) f^. Potassa; Subcarbonatis calidi, Olei Terebinth, £iij. — The oil of tur- pentine is gradually blended with the hot suhearbonate of potassa in a heated mortar. Indolent swellings were formerly rubbed with this application, and, perhaps, some chronic affections of the joints might still be bcuefliied by it. : A.RCOCE'* E. ffrom slide, Diseases of.) SARCO'MA, or Sarcbsis. (from cctp£ , flesh.) A fleshy tumour on any part of the body. (See Tumours, Sarcomatous.) SARSAPARI LLA The root of sarsapa rilla was brought into Europe about 1530. It was at first reputed to possess singular effi- cacy in venereal cases ; but afterward lost -all its fame. Sarsaparilla was again brought into notice' by Di. \V. Hunter, who advised Dr. Chapman to make trial of it in a bad case of phagedenic bubo ; and the benefit obtained in t his instance, led Dr. Hunter to extend the recommendation of the medicine Sir W. Fordyce stated, that sarsaparilla would quickly relieve venereal headachs, and nocturnal pains, and if persisted in, cure them ; that in emaciated or consumptive ha- bits, from a venereal cause, it was the great- est restorer of appetite, flesh, colour, and strength, which he knew of; that when mer- curial frictions had been previously employ- ed, it would generally complete the cure of the disease of the throat, nose, palate, or spongy bones ; and that ii would promote the cure of blotches and ulcers, and some- times accomplish it, even without mercury ; though, in this circumstance, there was dan ger of a relapse. Sir YV. Fordyce pronoun- ced sarsaparilla to be of little use in chan- cres ; but that when these, or buboes, could not be healed by mercury, it would often cure, and always do good. He allows, how ever, that, in all venereal cases, sarsaparilla is nol to be trusted, unless preceded by, or combined with, the use of mercury ; and he thought sarsaparilla would, probably, always cure what resisted mercury. (Medical Obs. and Inq. Col. 1.) The celebrated Cullen considered sarsa- parilla as possessing no virtues of any kind ; for, says lie, “tried in every shape, 1 have never found it an effectual medicine in sy- philis, or any other disease.” (Mat. Med. Vol. 2.) Mr. Bromfield declares, that he never saw a single instance in which sarsaparilla cured the venereal disease without the aid of mercury, either given before, or in con junction with it. (Tract. Obs. on the Use of Corrosive Sublimate , tyc. p. 78.) Mr. Pear- son also contends that sarsaparilla has not the power of curing any one form of the lues reverea ; but ho allows that it may suspend,. SCROFULA 40o Jtor a tune, tlx* ravages of that contagion, the disease returning if no mercury should have been used. This gentleman ndinits, also, that sarsaparilla will alleviate symptoms de- rived from the venereal virus. He maintains, that the exhibition of sarsaparilla does not diminish the necessity for giving les« mercu- ry. Nocturnal pains in the limbs, painful en- largements of the elbow and knee, mem- branous nodes, cutaneous ulcerations, and certain other symptoms, resemhling venereal ones, are often experienced after a full course of mercury. Such complaints. Mr. Pearson allows, are greatly benefited by sarsaparilla, and exasperated by mercury ; and he ob- serves, that it is from these complaints ha- ving been mistaken for venereal ones, that the idea has arisen, that sarsaparilla has cured syphilis when mercury had failed. Mer- cury, and the venereal poison, may jointly produce, in certain constitutions, symptoms W’hieh are not strictly venereal and are some- times more dreadful than the simple effects of syphilis. Some of the worst of these ap- pearances are capable of being cured by sar- saparilla, while the venereal viris still re- mains in the system. When this latter dis- ease has been eradicated by mercury, sarsa- parilla will also cure the sequelae of a course of the other medicine. ( Pearson on the Ef- fects of various Articles in ihe ire of Lues Venerea , 1807.) The value of many of the foregoing opi- nions is mucha fleeted by the results of mo dern inquiries into ihe nature of the vene- real disease, the possibility of generally curing which, without the aid of mercury, seems well established, though the expedien- cy of the method is another question. - SCALPEL, (from scalpo . to scrape.) Originally a raspatory, or instrument for scraping diseased hones, &c. The term now generally signifies a common, straight, sur- gical knife. SCA'RIFICATION. (from scariflco , to scarify.) The operation of making tittle cuts, or punctures, in a part, for the purpose ot taking away blood, letting out fluid in ana- sarcous cases, or air, in instances of emphy- sema. SCIRRHUS ; SCIRRHOMA 5 SCIR- RHO^IS. (from trHippcoe, to harden.) The etymological import ol these terms seems merely to be any induration. The first is now generally restricted to the induration which precedes cancer in the ulcerated state. SCLER1ASIS ; SCLER0-1S. (from anKn^ou, to harden.) A hard tumour, or m- dui lion. SCRO TULA, or SCROPHULA. (from scrofa , a sow.) So named, as is commonly supposed, because swine an- s>id to be sub- ject to it, though the correctness of this ety- mology is rendered very questiona le by the remarks of Dr. Henning, and the statement, that pigs are really liable to scroful < \ould appear to be erroneous. (See Critical In- quiry into the Pathology of Scrofula , fyc. p. 1,9.) Called also, struma , and t he King's evil, from the custom of submitting patients formerly to the supposed beneficial effects of the royal touch. A disease, one of 1 lie chief, or most palpable symptoms of which is a chronic swelling of the absorbent gland*, in various parts of the body, which glands ge- nerally tend very slowly to imperfect suppu- ration. Oar notions of scrofula, however, would be very imperfect, were we to define the disorder to be a morbid state of the Ijrn- phatie glandular system. The first appear- ances, indeed, frequent ly consist of spots on different parts of the body, and of eruptions and ulcerations behind the ears. As a ju- dicious author remarks, the system of absorb ent gland®, it is true, seldom or never fails to become affected in the progress of the dis- ease ; but there is reason to believe, that scrofula frequently appears, for the first time, in parts which are not of a glandular nature. Tin re are, perhaps, but few, if any, of the textures of the human body, or of the or- gans, which these textures form, that are not liable to attacks of scrofula, and to scrofula as an original idiopathic affection. (Thomp - son’s Lectures on Inflammation , p. 134.! These sentiments are entirely at variance with those of Alibert, and many other mo- derns, who describe the disease as having its commencement in the conglobate glands, especially thosp of the neck, (Nosol. Natu rclle , T. l,p. 441,4/o. Paris, 1817 ;) and they are equally opposite to the doctrine of Dr Henning, who argues, that the superficial ab- sorbent glands alone are susceptible of the original ac»ion of the cause of this disease, and that if other parts become affV- ted by it, such affe’ tion is consequential. (On the Pa- thology of Scrofula. Chap. 6.) Scrofula generally shows itself during in- fancy, between the age of three and seven ; sometimes rather sooner; but frequently as late as puberty, and in some instances, though a ver> few, not till a much more advanced period of life. In the latter cases, the dis- ease is said to be rarely so complete, or w ell marked, as it is in young subjects. u Cette maladie (says Alibi rt) est commun&ment le partage de la premiere enfauce. Ill est rare qu’elle se d 6 veioppe chez les adultes. Je Pai pourtnnt observee chez des septuage- naire- ; mais presque toujours, ce sont, les effects de la dentition qui la font eclore, et ceux de la | ubeite, qui la font evanouir (Nosol. Nalurelle,p. 448.) By some authors, it is stated, that the di- ease seldom attacks the glands in children under two years of age. Dr. Thomson,, however, ha- seen the glands affected before this period, and Dr. Cullen used to mention a case, in which the disease broke out in ari i fant only th>ee months old; which, ac- cor iing to Dr. Thomson, is uncommon. But though glandular scroful . occurs most fre- qu utly in child en, it is by no means confi- ned to that period of life. Di. Thomson has even found the lacteal gland- affected with scrofulous inflammation in per-ons of v<-ry advanced age. (Lectures on Inflammation , p 136.) Probably, however, such patients had laboured unfijr scrofulous complaints in their earlier days : and it merits notice; that SCItOfU L \ m some authors, like Dr. Henning, ( Z\ 110.) do not regard enlargement of the mesente- ric glands, as an unequivocal specimen of scrofula It is observed by Mr. Lloyd, that the susceptibility of different parts to the dis- ease “ is altered by age; thus, in children, the upper lip, eyes, glands of the neck, and those of the mesentery, are generally the pan's first affected; the lungs, bones, and other parts being subsequently attacked. It happens sometimes too in children, that small lumps iorm under the skin in various parts of the bod), which suppurate, ulce- rate, and pursue the same course with scrofu- lou- abscesses in general.” (On the Nature and Treatment of Scrofula, p. 5.) The same gentleman likewise states, that a species of warts also often forms about the face and neck of children of a scrofulous habit, but seldom in adults. “ In more advanced age, the eyes, upper lip, and lymphatic glands are comparatively seldom affected ; while the lungs, the other viscera, and the spongy parts of the boms are frequently attacked.” Scrofula is also as hereditary as any dis- ease can be ; that is to say, it is so as far as any particular kind of temperament, or con- stitution, can descend, more or less com- pletely, from parents to children. Mr. White, Dr. Henning, and others have strong- ly censured calling the disease hereditary ; but their observations only lead to these conclusions, that children, born of scrofulous parents, are not invariably affected with scrofulous diseases ; and that sometimes one child has some strumous affection, w hile the parents, and all the rest of the family, have no appearance of scrofulous habits. How- ever, I still conceive that neither Mr. White, nor any other writer will maintain the opi- nion, that scrofula does not much more frequently afflict the children of scrofulous parents, than the offspring of persons who have always been perfectly free from every tendency to any form of this affliction. Too numerous are the facts which occur to my ow n mind, to allow me to entertain the smallest doubt, that scrofula runs very much in certain families. In this sense, I think the term hereditary perfectly accurate and allowable. But, at the same time, I beg the reader to understand, that 1 have no intention of questioning what seem to be irrefragable truths, viz. that the children of scrofulous parents often continue, as long they live, entirely free from the disease ; and that one child is sometimes afflicted, while its father, mother, brothers, sisters, and all the rest of its relations, have never had any tendency to strumous disorders. It, should also be recollected, that the doc- trine of a congenital tendency to ihe dis- ease in particular families is one which in- terferes with some theories which have been offered about the predisposing cause of the disease, as for instance, with that of Dr. Henning, w ho declares that such cause is foreign to the body, and depends upon peculiarities of climate; (On the Pathology of Scrofula, p. 69, &c.) an Opinion, which is incorrect only in rej ect to its exclusion of the iniluence of oiher circumstances. Two curious specimens of tuberculated lungs in the foetus are preserved in Mr. Langstaff’s museum, and have been adduced by Mr Lloyd, as positive proofs of scrofula being hereditary, (On Scrofula , p. 23 ;) how- ever, I am not certain that they will be admitted as such by all parties, as tubercles of the lungs are not constantly regarded as a scrofulous disease When scrofula does not actually take place at a very early period of life, it is ge- nerally staled by writers, that the particular constitutions, in which there is a disposition to the disease, are, in a certain degree, dis- tinguishable. In the individuals, possessing the disposition in question, a peculiar soft- ness and flaccidity of fibre are remarkable ; their hair is more frequently light coloured than dark ; and tbeir eyes are said to be more often of a blue, than any other colour. Their skin is generally very fine, and even handsome, both in regard to its outward texture and complexion. Subjects with scrofulous constitutions frequently have a thickening of the upper lip ; this swelling is sometimes very considerable, and occasion- ally extends as far as within the nostrils. Scrofula is also very often complicated with rachitis, or follows the latter affection; but there is as little reason for supposing rickets to arise from scrofula, as this latter from rickets. In some instances, however, the complexion is dark, and the skin coarse ; but in these subjects, at least wben young, the face is generally tumid, and the look unhealthy. (Burns on Inflammation , Vol. 2, p. 232.) In many instances, the last joints of the fingers have been observed to be enlarged, and the belly is generally larger than usual. (Thomson, p. 134.) Mr. White, as I think, with some appear- ance of truth, denies that gray, or blue eyes, light hair, and a fair complexion, ought to be considered as marks of a scrofulous dis- position ; for the majority of children in this country have light hair, and eyes while young, which become darker as they ad- vance in life. Now, as the majority of scro- fulous patients are children, and young sub- jects, and as most children in this country have naturally the kind of hair and eyes above described, it seems inaccurate to lay any stress on persons affected with struma, or predisposed to this disease, having such appearances. (See White on the Struma or Scrofula, p. 38, Ed. 3.) However, it is to be recollected, that the greater frequency of scrofula in fair people is noticed in France, where the eyes are mostly dark. Thus, Alibert in his description of a patient disposed to the disease, takes notice of his swelled nostrils and upper lip; his florid complexion ; his fair, delicate, glossy skin ; his cheeks of a lively red colour; circum- scribed, however, by a pallid bloatedness of the rest of the face. His blue eyes ; di- lated pupils ; light hair ; short neck ; largo head and lower jaw ; flabby flesh ; large, protuberant belly ; strong intellectual SCROFULA 405 powers, &e. (Nosol. Naturelle , p. 442 ; also, Did. des Scietices Med. T. 50, p. 2S1.) Dr. Thomson expressly declares, that some of the worst cases of scrofula, which he has seen, occurred in persons whose com- plexion and hair were of a very dark co- lour. ( Lectures , p. 134.) Another fact, which I think tends to impeach the accura- cy of the common doctrine about complex- ion, is the circumstance of so many negroes being afflicted in this country with scrofula in its worst forms. Does not this fact indi- cate, at the same time, that it is climate, which is most powerfully concerned in the production of the disease ; since the African black, in his own country, is nearly ex- empt from scrofula? After all, however, as the disease is undoubtedly very frequent in persons of fair skin, light eyes, he. the term alike , at least in the sense of equally , may not be altogether correct in the following inference, viz. ‘‘ that persons of every va- riety of complexion are alike subject to this disease, and that it is only necessary to place them in circumstances favourable to its developement, to have it fully formed.” ( Lloyd on Scrofula , p. 7.) 1 believe the fact is now almost generally admitted, that females are rather more sub- ject than males, to scrofulous disease. (See Alibert , Nosol. Vaturelle, p. 449.) According to Mr. White, struma prevails more extensively in temperate latitudes, than in very hot or very cold climates. It is also more frequent in some parts of Eu rope than others ; and in this country it has been found to be most general in the coun- ties of Suffolk and Lancashire. At all pe- riods, it seems to have been a very common complaint in this island. From history, we learn, that it was denominated the king’s evil in the time of Edward the Confessor, who is supposed to have been the first that attempted to cure it by the royal touch. From a register kept in the royal chapel, we find that Charles the Second touched 92,107 persons, in a certain number of years ; and this equally bigoted and useless practice was not discontinued till a recent period, when kings were found to be, as well as their poorest subjects, totally desti- tute of all supernatural pow'er. Scrofula is not communicable from one person to another ; neither can it be con- veyed into the system by inoculation. The opinion also that scrofulous nurses may in- fect children, seems quite destitute of foun- dation. (See White, p 56, 57.) Pinel and Alibert have purposely kept scrofulous and healthy children together in the same ward, without any of the latter receiving the complaint. Hebreard could not communicate the disease to dogs by ino- culation. And G.T. Korturn, whose valua- ble work contains every thing know n about scrofula at the period when it was written, tried in vain to impart the distemper to a child, by rubbing its neck every day with the pus discharged from scrofulous ulcers. Lepelletier, desirous of ascertaining the correctness of such experiments, has of late repeated them, he has made guinea pigs swallow scrofulous matter, and he has in jected it into the veins, and applied it to wounds ; but in no instance was there even a temporary appearance of the disease be ing communicated. The same author also mixed scrofulous with vaccine matter, and inoculated with it ; yet he never found the vaccine vesicle, thus produced, deviate in the least from its regular course. Lastly, Lepelletier inoculated himself with pus, dis- charged trom scrofulous sores, as well as with the serum, collected under the cuticle of a strumous patient after the application of a blister ; but he has remained free from every scrofulous ailment. (See Did des Sciences Med. T. 50, p. 294.) Our country- man, Mr. Goodlad, inoculated himself seve- ral times with the discharge from scrofulous sores and abscesses, and the result was, that the disease could not be thus transmitted. (On the Diseases of the Vessels and Glands of the Absorbent System, p. 113.) The parts which ^re most frequently affect- ed by scrofula, next to the lymphatic glands, and perhaps the skin, are the spongy heads of the bone*, and the joints. The form which the disease assumes in the latter parts, is particularly described iu the article Joints The disorder of the spine, attended with a paralytic affection of the lower extremities is no doubt very frequently of scrofulous ori- gin. (See Vertebree.) The spina bifida is a congenital disease, which is found to occur most frequently in children whose parents are scrofulous. (Thomson's Lectures, p. 133.) The abscess, which forms in the cellular sub- stance, between the peritoneum and psoas muscle, is often regarded as a strumous dis- ease ; and when the contents of the abscess are found to contain flakes of a curdy mat- ter, somewhat resembling white, -of-egg, a substance peculiar to scrofulous abscesses, no one can doubt that the complaint is con- nected with this constitutional affection. (See Lumbar Abscess .) The chronic enlarge meat ot the thyroid gland, is sometimes con- sidered as scrofulous : but though patients, with this affliction, very often have, at the same time, other complaints, w hich are une- quivocally strumous, though the enlargement of the thyroid gland most frequently com mences at an early period of life, like scro- fulous diseases, and (hough, like them, it is sometimes benefited by the carbonate of soda, the opinion, I think, is rather on the de- cline. (See Brontliocele.) Scrofula also frequently makes its appearance in the form of imperfect suppurations in various parts of the body ; the contents of such abscesses bping a curdy kind of matter, and the skin covering them having an unhealty red ap- pearance, and a thickened doughy feel. The mesenteric glands are often found univer- sally diseased and enlarged in scrofulous sub- jects ; and as all nutriment has to pass through these parts, before it can arrive in the circulation, we cannot he surprised at the many ili effects which must be produced on the system, when such glands are thus diseased. However, as l have already hint 406 SCROFULA erf, doubts are entertained by Dr. Henning, whether enlarged mesenteric glands are de- cidedly scrofulous ; but if his sentiment be incorrect 1 fear he has been led to adopt it by wis particular theory, which limits the ori- gin of scrofula to the superficial absorbent glands. Scrofula frequently makes its attack on the testicle. (See Testicle , Diseases of.) The female breast is also subject to scrofu- lous tumours and abscesses Dr. Thomson believes, that more or less local inflammation occurs in every form and stage of scrofulous diseases. He observes, that the swellings are very often from the first attended with a sensible increase of heat and redness, and lh -t the pain, though sel- dom acute, is always present in a greater or less degree. Pressure on scrotulou- swell- ings never fails to create pain ; and the tem- perature of the skin covering them, is usu- ally two or three degrees hi her than that of the contiguous parts. ( Lectures , fyc. p. 131.) Scrofulous inflammation (as Mr John Burns observes.) is marked by a soft swell- ing of the affected part, which very fre- quently is one of the lymphatic glands. The covering, or coat of tlje gland, be- comes slightly thickened, and its substance more porous and doughy. The swelling increases, and the doughy feel changes by degrees into that of elasticity, or fluctuation, and a firm, circumscribed, hardened margin, can be felt round the base of the tumour. The skin is slightly red. If, at this time, an incision, or puncture, be made, either no . matter, or very little is evacuated, the lips of the wound inflame and open, displaying a sloughy-looking substance within ; and, betwixt this and the skin, a probe can often be introduced for some way all round If, however, the disease should have advanced further, then there is very little elasticity in the tumour; it is quite soft, rather flaccid, and fluctuates freely; the skin becomes of a light purple colour, and small veins may be seen ramifying on its surface. Some time after these appearances, the skin be- comes thinner at one particular part, and here it is also generally rendered of a darker colour. It afterward bursts, and discharges a thin fluid, like w hey, mixed with a curdy matter, or thick white floccuii. The red- ness of the skin still continues; but the aperture enlarges as the tumour subsides, and thus a scrofulous ulcer is produced. The margins of this kind of sore are gene- rally smooth, obtuse, and overlap the ul- cer ; they are of a purple colour, and rather hard and tumid. The surface of the sore is of a light red colour ; the gra- nulations are flabby and indistinct, and the aspect is of a peculiar kind, which, says Mr. Burns, cannot be described. The discharge is thin, slightly ropy, and copious, with curdy flakes. The pain is inconsidera- ble. When this ulcer has continued for some time, it either begins slowly to cica- trize, or as more frequently happens, the discharge diminishes and becomes thicker. An elevated scab is next formed, of a dirty white, or yellowish colour. This continues on the part a good while ; and when it falls off', leaves the place covered with a smooth purple cicatrix- Mr. Burns adds, that the preceding description corresponds to the mild scrofula, or the struma marisuela of the old writers This gentleman next re- marks, that occasionally, especially if a bone be diseased below the ulcer, the sore has a more liery appearance, the surface i dark-coloured, the margins soft, elevated, and inflamed, and sometimes retorted. The discharge is watery, the pain very consider- able, and the surrounding skin inflamed. This has been called the struma maligna. Such overacting scrofulous sores are most frequently met with over the smaller joints, particularly those of the toes. (Burns.) Sometimes a scrofulous abscess, after it has burst, forms a sinus ; the mouth of which ulcerates, and assumes the specific scrofulous appearance, w hile the track of the sinus still continues to emit a discharge. Mr. Burns also remarks, that scrofulous swellings are often disposed to subside in w inter, and recur on the approach of summer; but, he adds, that this is not an invariable law'. The glandular enlargements are very apt to become smaller, in a short time, in one place, wrfiile other glandular sw'ellings origi- nate with equal suddenness, somewhere in the vicinity of the former ones. Ulcers, also, very often heal upon the appearance of the disease in other parts. (See Disser- tations on Inflammation , Vol 2, 1800.) The glandular swellings, which occur in syphilis, says Dr. Thomson, are of a more acute character, than those w r hich proceed from scrofula. They arise from the absorp- tion of a specific poison ; and they do not, like those of scrofula, admit of a spontane ouscure. Chronic swellings of the lymphatic absorbent glands occur also in carcinoma ; but these manifest little or no disposition to suppuration ; they succeed most frequently to carcinomatous indurations, or ulcers ex- isting in the neighbourhood of the glands affected ; and they are accompanied in their progress and grow th by a peculiar lancina- ting pain. (See Thomson on Inflammation , p. 135 ) With regard to the proximate cause oi scrofula, medical men may be said to re- main, even at the present day* ’ n entire ig- norance of it. After the ridiculous theory, referring scrofula to certain humours in the constitution, or chymical changes in the blood, had been exploded, the opinion gra- dually arose, that it was a disease of the lymphatic system ; and indeed, that the ab- sorbent glands are often visibly the seat of its attack, when no changes are distinguish- able in other textures, is a fact, that admits of no dispute. I believe, at the same time, that whoever supposes scrofula to be ex- clusively confined to the lymphatic system, must have a very imperfect conception ot what is really the case. On the contrary, I fully participate in the sentiments of Pro- fessor I homson, already adduced upon tins • point, and in the belief of another modem SCROFULA. •writer, that strumous complaints t{ are not to be considered as dependent on disease of any particular system, as the lymphatic.” {Lloyd, p. 10.) Such writers as have fixed upon the absorbent vessels, as the particular seat of scrofula, can throw no useful light upon its origin, by following up the theory, whether they imagine the cause to be ob- struction of the vessels and glands ; or take up the wild speculation of Cabani, that in scrofula, the mouths of the lymphatics are in a state of increased activity, while the vessels themselves are in a state of atony ; or the doctrine of Soemrnerring, that scro- fula depends upon a passive relaxation and dilatation of the absorbents ; or the hypo- thesis of Girtanner, that these vessels are in a state of increased irritability. The idea of obstruction being the cause, has of late years been much on the decline ; and that the convolutions of lymphatic vessels, forming the glands, are quite pervious, and may readily be injected, even when diseased, is a fact, first demonstrated by Soemrnerring, which must weigh heavily against this opi- nion. Of the exciting causes, very little is also known. Mr. John Hunter remarks, that “ in this country, the tendency to scro- fula arises from the climate, which is in many a predisposing cause, and only re- quires some derangement to become an im- mediate cause, and produce the whole dis- ease.” (Treatise on the Venereal Disease, p. 20.) The disease is remarked to be most common in females ; in cold, damp, marshy countries, and in all places near high moun- tains, where the temperature is subject to great vicissitudes. “ Nous voyons presque toujours, (says Alibert) que les tumeurs et ies ulceres se rouvrent au printemps pourse fermer ensuite vers la canicule.” (Nosol. Naturelle, p. 449.) In the work quoted the last but one, Mr. Hunter takes notice of slight fevers, colds, small-pox, and measles, exciting scrofulous diseases. He observes, that in particular countries, and in young people, there will sometimes be a predisposition to scrofula : and that, in such subjects, buboes will more readily become scrofulous. ( P . 27.) In short, it was one of Mr. Hunter’s opinions, and probably a most correct one, that the venereal disease is capable of calling into action such susceptibilities as are remarkably strong, and peculiar to certain constitutions and countries ; and that, as scrofula is pre- dominant in this country, some effects of other diseases may partake of a scrofulous nature. (P. 96.) Mr. Hunter, speaking of venereal buboes, mentions his having long suspected a mixed case, and add 3 , I am now certain that such exists. I have seen j/jases, where the venereal matter, like a col.d, or fever, has only irritated the glands 1 to disease, producing in them scrofula, to which they were predisposed. In such ca- ses, the swellings commonly arise slowly, give but little pain, and seem to be rather hastened in their progress, if mercury is given to destroy the venereal disposition, ^ome come to suppuration, while under 407 this resolving course ; and others, which probably had a venereal taint at first, be- come so indolent, that mercury' has no ef- fect upon them ; and in the end, they get well of themselves, or by other means.” (P. 269.) For such buboes, Mr. Hunter used to recommend sea-bathing ; and, in case of suppuration, poultices made of sea- water. In the words of a well-informed Profes- sor, scrofula readily forms an alliance with almost every morbid affection, occurring either from external injury, or from internal disease ; it modifies the appearance of other diseases, and seems to convert them gradu- ally into its own nature. Indeed, there are few of the local inflammatory affections, which occur in this country in which the symptoms and effects of these affections, and the operation of the food and remedies employed for their cure are not morn or less modified by the -degree of scrofulous diathesis, which prevails in the constitution of those who are affected by them. The scrofulous diathesis, wherever it exists, usu- ally gives more or less of a chronic charac- ter to local inflammatory affections. (Thom- son's Lectures, p. 131.) It ba- been the fashion of late years to ascribe the origin of a vast number of dis- eases to disorder of the digestive organs, little tro able being generally taken to con- sider with any impartiality whether the de- rangement of those organs may not be rather the common effect, than the common cause, of so many various diseases. Nume- rous circumstances tend to perpetuate the delusion, into who h y< ung practitioners are falling upon this topic. They see various diseases, attended with dyspepsia, flatulence, loss of appetite, costiveness-, and a torpid state of the bowels ; they observe that such diseases and the latter con, plaints of the alimentary canal, generally diminish toge- ther ; that, when the functions of the sto- mach and bowels are deranged, any other diseases, which the patient may be labouring under, either grow worse, or are retarded in their amendment ; and, lastly, the treat- ment, to which the theory leads, improves the health, by rectifying the state of the alimentary canal, and the sore, tumour, or other complaint, in the end, with the addi- tional aid of time, nature, and other favour- able circumstances, gets well But, how- ever simple, % safe, and benefioiaftbe prac- tice may be, and plain as the facts are which lead to it, there is no proof, that the other disease was truly a consequence of the disorder of the digestive organs. The latter symptom i believe, is very frequently an effect mistaken for a cause, and perhaps, always so, in relation to scrofula. Besides, if it were to be assumed, (as indeed it actu- ally is) that, in scrofula “ there always is more or less disorder of the digestive or- gans, and primarily ;.f no other important function, ” 1 do not see that we advance one step hearer the truth ;. because as the same cause is generally assigned, by gentlemen attached to this theory, for a vast number 40S SCROFULA. of other eases, we stilt remain in the dark, as to the circumstances, which make so many complaints of different kinds spring from one and the same cause. These cir- cumstances, though buried in silence, are still the mystery — still the secret which is desired ; and, if it be answered, that the ef- fect will only happen in particular constitu- tions, then we are brought back at once to the point from which we lirst started, viz. that scrofula is a disease depending upon some unknown peculiarity of constitution, congenital or acquired, and capable of be- ing excited into action by various causes, as climate, mode of living, &.c. However, lest I may not have attached sufficient im- portance to the doctrine of gastric disorder being the cause of scrofula, I feel pleasure in referring, for the arguments in its support, to the writings of Mr. Abernethy, Dr Car- michael, and Mr. Lloyd, whose sentiments appear highly commendable, as far as they tend to teach surgeons rather to place con- fidence in means calculated to improve the health in general, as the most likely mode of benefiting the scrofulous patients, than to encourage foolish dreams about new spe- cifics for the distemper. Thus far, 1 can follow these gentlemen safely ; but no far- ther, except as a sceptic. However, per- haps none of the believers in the effect of disorder of the digestive organs mean to say, that such disorder is any thing more than one of the many exciting causes of scrofula ; and with this qualification, then- theory may, or may not, be correct. It is the doctrine of Alibert, and indeed of near- ly all writers : “ ce sont, les vices de la puissance digestive, qui preparent de loin ies scrophules. Rien n’ infiue davantage sur leur developpcment que la mauvaise qualite des alimens, &.c.” ( Nosol Naturelte, p. 449.) “ Ajoutez a cet cause le sejour dans les habitations malsaines;” But, every explanation, even of exciting causes, re- mains unsatisfactory, as long as we find children living in the same air, under the same roof, and feeding and sleeping toge- ther, and clothed also exactly alike, yet, only one or two of them become scrofulous, while all the rest continue perfectly free from the dise'ase. Here, then, we are again compelled to return to predisposition, con- stitution, diathesis, and a congenital tenden- cy to the complaint, as a solution of the dif- ficulty. In short, then, respecting the eti- ology of scrofula, little is known, except that certain constitutions probably have a congenital disposition to the disease ; that such disposition may probably be increased, or diminished, by the operation of climate, mode of life, age, tkc. ; and that irritations of a thousand kin s nay excite, the disease into action, when the system is predisposed to it, by inexplicable causes. That otirnate has great influence cannot be doubted, when it is reflected, that the inhabitarWs of certain countries, in which the temperature is invariably warm, never suffer from scro- fula. There ca n be no doubt that, with age, the disposition to scrofula diminishes) for, children much afflicted while young, frequently get quite well when they ap- proach the adult state ; and, if a person has remained perfectly free from any mark of a scrofulous constitution till the age of twenty-five, he may be considered as near- ly out of all danger of the disease. TREATMENT OF SCROFULA. “ For the cure of scrofula, (says the cele- brated Cullen,) we have not yet learned any practice that is certainly, or even generally successful. The remedy which seemstobethe most successful, and which our practitioners especially trust to, or employ, is the use of mineral waters But, (adds this eminent physician,) in very many instances of the use of these writers, l have not been well satisfied, that they had shortened the duration of the disease more than had often happened when no such remedy had been employed. With regard to the choice of the mineral waters most fit for the purpose, (says Cullen,) 1 can- not with any confidence give an opinion. Almost all kinds of mineral waters, whether chalybeate, sulphureous, or saline, have been employed for the cure of scrofula, and seem- ingly, with equal success and reputation ; a circumstance, which leads me to think, that if they are ever successful, it is the element- ary water that is the chief part of the remedy. Of late, sea-water has been especially re- commended, and employed ; but, after nu- merous trials, I cannot yet discover its superior efficacy. ” ( First Lines of Physic, Vol. 4.) On the subject of mineral waters, Dr. Thomson very properly remarks, that they are now usually employed as pur- gative and tonic remedies, and not as speci- fics. In employing them it is often difficult to distinguish between the effects, which they in reality produce, and those which are to be attributed to the slow operation of time, thfe season of the year, change of situation, alteration in the mode of life, or exercise in the open air. ( Lectures on Jn- flammatiom, <^c. p. 195.) In scrofulous diseases, Dr Fordyce had a high opinion of bark ; and he endeavoured to prove, that, in cases of tumefied glands, at- tended with a feeble habit, and a weak cir- culation, it is a most efficacious medicine, and acts as a resolvent and discutient. He also brings forward a case, in support of bark being a means of cure for the ophthalmia strumosa. (See Med. Obs. andlnq. Vol. \,p 184.) Dr Fothergill, in the same work, p. 303, writes in favour of the good effects of bark in similar cases ; small doses of ca- lomel bei »g sometimes given with it. Dr. Cullen considered the efficacy of bark in scrofula very dubious and trivial. ^ First Lines } fyc. Vol. 4.) According to Mr. Burns, bark has been frequently found useful in the cure of scro- fulous inflammation, but more often of ulce- ration, than tumefaction of the glands. But, says he, it does not appear to possess, bv any means, that certain power of curing scrofulous SCROFULA. i u'J affections, which is attributed to it by Dr. Fothergill and several other authors. He observes, that we are not to suppose it will infallibly cure scrofulous inflammation, or ulceration of parts, which, even when af- fected with simple inflammation, are very difficult of cure. If it be difficult to cure a simple inflammation, or ulceration, of a rendon, cartilage, or bone, we must not be disappointed if even a specific remedy for scrofula, (were such ever discovered) should prove ineffectual in procuring a speedy re- storation to health. Mr. Burns contends, that bark is often ineffectual, because impro- perly administered. Given in small quan- tities, once or twice a day, it may prove a stomachic, and increase, like other tonic bitters, the power of the stomach, or the functions dependent on it ; but, in order to obtain the benefits of the specific action of bark, he maintains, that it should be given in large quantities, for several weeks, with a good diet, air, and proper exercise. — Disser- tations on Inflammation, Vol. 2, p. 371.) Dr. Thomson does not believe, that bark, or iron, has any specific virtue in curing scrofula ; but, he admits, that either of these medi- cines may sometimes prove useful in proving the tone of the digestive organs, when given after, or occasionally along with, a course of purgative mineral waters. {Lectures, p. 197.) As far as I can judge, Mr. White has with much reason recommended paying attention to such circumstances as may have effect in preventing the disease, viz. air, cleanliness, exercise, and diet. He mentions cold-bath- ing among the preventives of struma, and speaks of sea-bathing as being the best. He advises attention also to be paid to the manner of clothing children, keeping them more covered in winter than summer. Mr. White thought, that allowing children to sleep a great deal was prejudicial ; but this seems to me only conjecture. In noticing the treatment of the disease, Mr. White states, that “ the general idea of the struma is, that it is a disease of debility ; and therefore, the great object is, to invigo- rate the habit by every possible means ; the chief of which are tonic medicines, and sea- bathing. Some are of opinion, that in the case of young patients, this should be con- tinued, during the summer months, every year, to the age of fourteen or sixteen. Many recommend it, not only in the sum- mer, but throughout the year; whilst others are for administering alteratives, principally the alkaline salts, with or without anti- monials, and the different tonics, during the winter ; a nd the sea-water and sea-bathing, or cold-bathing, during the summer, for a conti- nuance of two or three years from the com- mencement of the disease ; with this general observation, that they will outgrow the com- plaint.” Mr. White adds, that the chief exter- nal means are fomentations of sea- water, and cataplasms, made with the same. With re- spect to regimen, some recommend a milk and vegetable diet ; others animal food and fermented liquors. Vol, II. Mr. White maintains, that the preceding plans of treatment are not, in general, effi- cacious, though, in some instances, they may prove useful. “ In early affections of the lymphatic glands, (says this gentleman,) and from the want of a pure air, and proper exercise, where children are delicate and irritable, a change of situation to the sea- side, together with bathing, when they have acquired some strength, must be exceeding- ly proper ; and, in gross plethoric subjects, who have diseased lymphatics, from impro- per feeding, and want of necessary exercise, a journey to the sea-coast may be very use- ful, particularly if the salt-water is drank often, and in a sufficient quantity to become purgative. This, with the novelty of their situation, which may naturally produce an increase of exercise, might answer every expectation ; but these are the kind of cases that, with a very little attention, are easily cured. ( White on the Struma, Edit. 3 ,p. 104.) The conclusion, to which Mr. White’s re- marks upon this part of the subject tend, is, that sea-bathing only deserves praise, as a preventive, and in the early stages of the disease. He particularly condemns cold-bath- ing, for poor, weakly, debilitated children, whose thin visage, enlarged belly, and fre- quent tickling cough, sufficiently indicate diseased viscera ; such do not recover their natural warmth, after cold-bathing, for hours, and their subsequent headach, livid lips, and pale countenance, are sufficient marks of its impropriety. ( P . 107.) Dr. Cullen entertained a very favourable opinion of cold-bathing, since he affirms, that he had seen scrofulous diseases more benefited by it, than any other remedy. ( First Lines of Physic , Vol. 4.) “ Cold-bathing, especially cold sea-bath- ing (says Mr. Russell) is a remedy universally employed in scrofula, and I believe with great advantage in many cases ; for it not only appears to improve the patient’s gene- ral health and strength, but likewise to pro- mote the tumescence of enlarged glands, and the resolution of indolent swellings in the joints, even after they have attained a considerable size, and have existed for a great length of time. But, in order that cold-bathing may be practised with safety and advantage, the constitution must have vigour to sustain the shock of immersion without inconvenience. If the immersion be succeeded by a general glow over the surface of the body, and the patient feels cheerful, and has a keen appetite, we may conclude that the cold bath agrees with him ; but if he shivers on coming out of the water, con- tinues chill, and becomes drowsy, we may be assured that the practice of cola-bathing does no good, and had better be omitted. li In estimating the comparative merit of cold-bathing and warm-bathing, in the cure of scrofulous complaints, my own experience, together with the result of different conver- sations on the subject with some of the most judicious practitioners of my acquaintance, would lead me to bestow much more com- mendation on the effects of warm-bathing. 1 52 410 SCROFULA. should not even be inclined to circumscribe the practice to cases of emaciation and de- bility, since from observation, I am fully satisfied with regard to the beneficial etfects of the warm bath to patients of plethoric constitutions, who were much affected with those swelled scrofulous glands. Several of instances occurred in young women, about the prime of life, who were in all res- pects healthy and vigorous, abating the swellings of the glands, and those symptoms of distress which were connected with ful- ness of blood. “ The sensation of the warm bath is ex- ceedingly grateful to most patients, and the practice is universally safe. It may be em- ployed at all seasons of the year, and in all weather, without danger or inconvenience ; the risk of suffering from exposure to cold, immediately after immersion in the warm bath, having been much magnified by preju- dice. There is not even any good reason to believe in the existence of such a risk. The precautions, however, which are employed to avert it, are perfectly innocent ; and pro- vided they do not impose any unnecessary and incommoding restraints upon the prac- tice, may be encouraged, so far as to relieve the patient’s mind from uneasiness and groundless apprehensions. “ It requires many weeks, and sometimes several months, to ascertain the full effects of warfil-bathing in relieving scrofulous com- plaints ; but, as the practice is not attended with any inconvenience, nor followed by any bad consequence, there can be no rea- son to intermit the course, till the trial is completely satisfactory ; and I am convin- ced, that the practice of warm-bathing, in cases of scrofula, will be more universally adopted, after the knowledge of its benefi- cial effects is more widely diffused.” (See Russell's Treatise on Scrofula.) Nothing can be more satisfactory (says Professor Thomson,) than the evidence which is on record, of the efficacy of the muriate of soda, as it exists in sea-water. In reading this, one only wonders how so effi- cacious a remedy should ever have fallen into neglect. (P. 196.) In a subsequent passage, however, the same gentleman evinces only a limited confidence in this means of relief. u Local sea-bathing, both cold and warm, has often appeared to be of use in procuring the resolution of scrofulous swellings. The temperature of the bath must always be varied according to circumstances, according to the season of the year, the strength and habits of the patient, and the particular effect, which the bath seems to produce. It is at all times difficult to distinguish between the effects immediately arising from the ap- plication of salt water to the body, and those which arise from the increased warmth of temperature in the bathing seasons of the year ; from the exercise which patients going to sea-bathing generally take in the open air ; from the change of situation and amusements ; and, among the poorer classes, from the more nourishing diet and exemption from labour, in which they are usually per- mitted to indulge, during their residing at sea-bathing ^quarters. It is not improbable, that those living on the sea-coast, who become atfected with scrofula, would for similar reasons, derive equal benefit by going from the sea-coast to reside for a time in the interior of the country.” (See Thom - son’s Lectures, fyc. p. 203, 204.) A still later writer declares his belief, that cold sea-bathing has no specific power over the disease. ( Lloyd on Scrofula, p. 43.) Yet the plain surgeon, in search of practical truths, will not care whether any plan has a specific power or not over a complaint, if that disorder is sometimes relieved by it. And, that this is the fact is admitted by Mr. Lloyd, when he says, u cold sea-bathing, however, is certainly useful when judiciously applied, &c. &c. - ’ (P.44.) With regard to electricity, Mr. While thinks it useful, when from length of time the enlarged glands have acquired a degree of hardness and insensibility. Mr. White, after enjoining attention to air, exercise, and diet, as promotive of a recovery, as well as a preventive of the disease, proceeds to explain his own prac- tice. The internal cases, which properly belong to the physician, we shall dismiss from consideration. The first external symptoms, such as swellings of the lips, side of the face, and of glands under the chin, and round the neck ; also other symp- toms, usually considered as strumous, viz. roughness of the skin, eruptions on the back of the hand, and different parts of the body, redness, and swelling of the eyelids, and eyes ; are accompanied, according to Mr While’s conceptions, with an inflammatory diathesis, though seldom such a one as to require bleeding. Calomel is the medicine, which this gentleman recommends for the removal of the foregoing complaints. It is not to be given in such quantities, as to render it a powerful evacuant, either by the intestines, or any other way; but, in small doses, at bedtime. Thus, says Mr. White, “ it remains longer in the intestinal canal, a greater quantity is taken into the habit, and the patient is less susceptible of cold, than when taken in the daytime. The first, and, perhaps, the second dose may prove purgative, which is, in general, a salutary effect; but, afterward, the same quantity will seldom do more, than is sufficient to keep the body open ; and should it fail of answering that purpose, I have usually re- commended some gentle purgative, every third or fourth morning, according to cir- cumstances. If there should be a prevail- ing acidity, a few grains of the sal sodec, magnesia, or some testaceous powder, may be added to the medicine. By this simple method (continues Mr. White) most of the symptoms before mentioned will, in a short time, disappear; but if the tumours should continue hard, and retain their figure, with- out dividing into smaller ones, we may de rive some benefit from external applications, particularly the steam of warm water. I have used a variety of medicinal herbs with SCROFULA. 41 j success; but am inclined to believe, that the advantage was principally derived from the warm water, kc. At other times, I have stimulated the part affected with elec- tricity, insulating the patient, and drawing sparks from the tumour, until a slight de- gree of inflammation was excited. After the application of the steam, or the use of the electrical machine, I have sometimes rubbed a little of the unguentum mercuriale into the tumour, and neighbouring parts, or applied the emplastrum saponaceum, or mercuriale cum ammoniaco, over the swell- ing, or a liniment with camphor, ol. oliva- rum, and sp. terebinth.” Mr. White adds, that in such cases, if the tumours should suppurate, and burst, the parts will, in most instances, heal without much trouble. For eruptions on the head, he recommends ap- plying the ung. saturn. album camphoratum, or the cerat. alb. cum hydrarg. prrecip. alb. For the roughness of the skin, which is ge- nerally followed by eruptions, he also ad vises the aqua-vegeto-mineralis, aqua calcis, solutions of sal. tartar, or of the hydrarg. raur. as outward applications. “ This last (says Mr White) will seldom fail to check the progress of the complaint, and dry the sores ; and in the quantity of ten or twelve grains, to a quart of warm water, the use of it will not be productive of any pain. If the eruption should ulcerate, and require any unctuous application, to prevent the adhesion of the linen, the ointment before- mentioned may be applied ;. the best re- medy will be warm-bathing, and when prac- ticable, the sea- water claims a preference.” (P. 114) The author next mentions his having occasionally recommended the vi- num antimoniale, tartarum emeticum, de- coctum Lusitanicum, decoctum lignorum, or sarsaparillae ; and that he sometimes found advantage derived from artificial drains. We need not detail this gentleman’s mode of treating affections of the eyelids, as notice is taken of scrofulous diseases of the eye and eyelids, in the articles Ophthal- my and Psorophlhalmy. For the cure of indurations in the breast, remaining after mammary abscesses, Mr. White speaks very highly of the effects of the steam of warm water; and cautions us against indiscriminately employing calomel, which will often affect the mother little, but the child violently. Mr. White mentions his employing a small tin machine, large enough to hold a pint and a half, or two pints of boiling water. From the top pro- ceeded a narrow tube, ten, or twelve inches long, through which the steam passed. .Near its end, which was moveable and curved, was a joint, for the greater conve- nience of directing the steam to the diseased parts. The water was easily kept boiling, by means of a lamp under the machine. Mr. White says, that the steam should be employed twice, or thrice a day, and a piece of flannel, or skin, afterward applied. The body should also be kept open. In obsti- nate, neglected cases, mercurial prepara- tions, according to Mr. White, must likewise be given, and, if they affect the child much, sucking should be suspended. (P. 117.118.) Mr. White speaks largely of the treatment of cases, in which the mesenteric glands are diseased ; but, this subject strictly be- longs to the physician. When, in these in- stances, the glands of the neck, or other parts of the body, tend to a state of suppu- ration, it is very slowly, the skin appearing uniformly thin, and of a deep red colour, and the tumour seeming flaccid. In such cases, Mr. White recommends the use of the lancet or caustic ; for if no artificial open ing is made, it will be a long time before the skin gives way; and when it does, the aperture will not only be very small, but often unfavourable in its situation. Mr. White adds, that the contents will often be more like mucus than pus, or like a mixture of both ; and the discharge wili continue for a great length of time, if no remedy is ap- plied. This gentleman mentions his having found a solution of gum myrrh® in aqua calcis, used as a lotion, and the ceratum saponaceum, or some similar outward ap- plication, the best method of treating this symptom. We need not describe Mr. White’s prac- tice in the treatment of scrofulous joints, as the subject is fully considered in the article Joints. It appears, however, that he con- firms the efficacy of stimulating applications, and pressure with bandages, w hen the fin- gers and toes are affected with strumous disease. (P. 143.) Whoever compares the practice of Mr. White in administering calomel, occasional purgatives, the decoctum Lusitanicum sar- saparilla, kc. with the blue-pill, sarsaparilla, and laxative treatment of the present day, will perceive no very material difference between them, especially when the stress, which Mr. White laid upon attention to diet, clothing, &,c. is taken into the account. Mr. Lloyd, who has detailed Mr. Abernethy's practice in scrofula, lays it dow n as an ax- iom, that “ the disease is only to be cured by avoiding all sources of irritation, and re- storing the natural and healthy functions of the digestive organs.” ( P . 48.) By sources of irritation, Mr. Lloyd means exciting causes ; the advice is therefore excellent, as far as it can be followed, or such causes are decidedly known. The restoration of the functions of the digestive organs is also a tiling worth aiming at, and the only dif- ference in my views from those of Mr. Lloyd is, that as I look upon the disorder of the digestive organs to be in general only a complication, or effect of the scrofulous disease, ulcer, abscess, diseased joint, kc. and not the exciting cause, the treatment, when beneficial, becoming so only on the principle of improving the general health, by the removal or diminution of one of the most hurtful consequences of the original disease. It is hardly necessary to inform the profession, that the treatment, described by Mr. Lloyd, in addition to the usual ad- vice about diet, clothing, the avoidance of damp and cold, and the utility of good air. SCROFULA. 4j2 exercise, &c. consists in giving the patient five grains of the pil. hydrarg. every night, and half a pint of decoct, sarsap. c. twice a day. And, if at a certain hour of the day, there has been no motion, recourse is had to opening medicines. This plan is pur- sued, till the bowels become regular; and then, with the view of preventing a relapse of the bowels into their former state, Mr. Lloyd continues the exhibition of alterative doses of mercury for an indefinite time, the preference being given to the compound calomel pill, in doses of five grains every night. In children, the practice is exactly like that of Mr. White, viz. small doses of calomel with purgatives. When acidity prevails in the stomach, small doses of soda are commended ; and when the stomach is weak, with loss of appetite, cinchona, steel, and mineral acids. A full diet, with porter and wine, is disapproved of, and, as already stated, not much confidence is placed in sea-bathing. ( Lloyd on Scrofula, p. 38.) Crawford, Pinel, and others, have tried the muriated barytes, as a remedy in scro- fulous cases. (Med. Communications, Vol. 2. JYosogr. Philo sophique, Pol. 2. p. 238.) It has the recommendation of the celebrated Hufeland. Mr. Burns says, that the muriate of barytes has no effect on diseased glands ; but that it is occasionally serviceable in scrofulous ulceration, though he adds that it deserves little dependence. ( Dissert . on Inftam. Vol. 2, p. 372.) This gentleman re- commends the following formula : fy. Terrae Ponder. Salit. Chryst. gr. x. Aq. Font. Aq. Cassiae, utriusque, ^iij. Syrup. Aurent. ^ij. Half an ounce of this may be given at first twice or three times a day, and gradually increased to such quantity, as the stomach can bear without sickness. At present few 7 practitioners have any faith in the antiscro- fulous virtues of the muriate of barytes ; and, as Dr. Thomson remarks, it has had a much shorter-lived reputation than sea- water, or its successor the muriate of lime. (See Lectures on Inflammation, p\ 196.) Fourcroy proposed trying the muriate of lime ; but its efficacy is very doubtful, and inconsiderable. “ Professor Thomson (says Mr. Russell) has favoured me with the fol- lowing observations on the effects of muri- ate of lime. He employed muriate of lime in various cases of scrofula, without having derived benefit from it in a single instance. Some patients, indeed, he admits, got well, while under a course of muriate of lime ; but then he had no reason to ascribe the cure to the effect of the medicine. In other cases, on the contrary, the muriate of lime produced severe sickness and oppression at the stomach, and the patients got daily worse, till the muriate of lime w as intermit- ted, and other medicines employed. The relief experienced from the intermission of the muriate of lime, left no doubt with re- gard to the injurious effects which the use of it had produced ; and from extensive ex- perience and accurate observation on the subject, Professor Thomson is satisfied, that muriate of lime is attended w r ith prejudicial effects in many cases ot scrofula. ' (See Russell's Treatise on Scrofula.) Since the publication of the last edition of this Dic- tionary, I have seen the muriate of lime given in several cases of scrofula ; hut with- out any beneficial effect on the disease. How long the muriate of lime will be per- mitted to enjoy its present fame, Dr. Thom- son will not venture to say ; but from what he has seen of its use, he imagines its repu- tation will only last, till some other new remedy is proposed by those, who are still sanguine in their hopes of discovering a specific for scrofula. (Lectures, tyc. p. 196.) Iron, given either alone, or joined with the fixed, or volatile alkali, also deserves very little confidence. Burnt sponge, millipedes, and sulphate of jspotassa, have all been ex- tensively tried ; the first of these is, in my opinion, sometimes useful in diminishing enlarged scrofulous glands ; and that it has this effect on bronchoceles, is indisputable. The Mariscbal de Rougeres employed a remedy composed of iron filings, muriate of ammonia, subcarbonate of potassa, &c. (Journ. de Med. tom. 40, p. 219.) Several narcotics have been tried, such as opium, hyoscyamus, the solanum dulca- mara, &.c. ; but, though their virtues against scrofula have been sometimes cried up very highly, the moderns have lost all faith in them. The attention of the public to the effects of cicuta, in cases of cancer and scrofula, was first particularly excited by the accounts of its virtues published by Ba- ron Stork. Fothergill also praises cicuta, and per- haps it is as good an internal medicine as can be tried ; but it is far from being gene- rally efficacious. It is highly deserving of recommendation for irritable scrofulous ul- cers. There is now not the least doubt, however, that the statements of Baron Stork are greatly exaggerated. He consi- dered cicuta indicated, whenever obstruc- tions and tumours existed ; and, under this treatment, he says that he found the swell- ings melt aw^ay like ice. What is extraor- dinary, every sort of tumour yielded to ci- cuta. But, (as Dr. Thomson judiciously re- marks) universal success is alw r ays one of the most suspicious circumstances, which can be mentioned in the history of the ef- fects produced by any new' remedy. (Lec- tures, fyc. p. 199.) Dr. Cullen frequently employed hemlock, and sometimes found it useful in discussing obstinate swellings ; but, he says, it also frequently disappointed him, and he never saw it dispose scrofulous ulcers to heal. With regard to mercury, we have already noticed, that calomel was much employed by Mr. White. Some have exhibited the sublimate : others the acetite of mercury. All these preparations have been at times conjoined with cicuta, antimony, &io. Ca- lomel is, perhaps, the best mercurial prepa- ration in scrofulous cases; but mercury, given internally with any view of exciting a salivation, is justly deemed hurtful by all the best practitioners. As ap alterative, and SCROFULA 413 an occasional purgative, it is undoubtedly a ly against antimony. As a modern writer good medicine for strumous patients. Mer- observes, no great dependence seems ever cury was much disapproved of by the to have been placed in the use of diaphoretic celebrated Cullen, as a medicine for scrofu- medicines for the cure of scrofula. The Ja. As a distinguished Professor observes : different preparations of antimony, indeed, “From the great apparent similarity of the have been occasionally administered ; but symptoms, progress, and seats of scrofula, chiefly in cutaneous affections, supposed to to those of syphilis, and from the well- he of a scrofulous nature. Guaiacum, sar- known effects of mercury in curing syphilis, saparilla, sassafras, and mezereon, singly, it need not seem strange, that medical men and in combination, have all been supposed should have been a little obstinate in their to be useful in the cure of scrofula ; but attempts to obtain benefit from the use of they are now seldom given with this view, mercury in scrofula. These expectations except in cases of scrofula combined with are in general abandoned, and mercury is syphilis, or excited by the too free and now given for the cure of scrofula as a injudicious use of mercury. ( Thomson's purgative only. Along-continued, or ini- Lectures, fyc. p. 199.) properly-administered course of this medi- With respect to Alibert’s practice, among cine, has often been known to aggravate all the vegetable bitters, he prefers the hop, the symptoms of scrofula; and, in many burdock, gentian, and bark. He seems to instances, to excite these symptoms in have no confidence in specifics, like hem- persons, in whom they did not previously lock, belladonna, aconitum, &.c. Neither exist.” (See Thomson's Lectures on Infiam- does he express himself favourably of alka- motion, p. 194, 195.) line medicines, the muriate of ammonia, Mr. Burns thinks the nitrous acid has and the muriate of barytes. However, he some effect in promoting the suppuration of praises the good effects of steel medicines scrofulous glands and tumours, and disposing on enlarged glands. He affirms, that he has ulcers to heal. He says, two or three drams seen most good derived from external means ; may be given every day, for a fortnight ; aromatic fumigations in an apparatus prepa- but if in this time it should do no good, its red by the cbymist Darcet. What he calls employment ought to be discontinued. The scrofulous eruptions, he covers with a mineral acids, diluted with water, (says Pro- strong solution of the nitrate of silver, fessor Thomson,) are often used with views Swelled glands he rubs with the antimonial similar to those, which guide us in the em- ointment. He commends also change of ployment of tonic remedies. Their medici- air, and the avoidance of low damp places ; nal powers appear to be nearly the same ; and speaks favourably of sea-bathing, sea but the nitric acid has of late been preferred, voyages, sulphureous mineral waters, and particularly in the scrofulous affections, particularly of the good effects derived from which are sometimes induced by the action the solar warmth. (See Nosol. JVat. p. 449.) of mercury. {Lectures, fyc. p. 197.) The local treatment, preferred by Mr. The pills containing carbonate of soda, White, has been already described. I hav« (see Pilulce,) and the different soda waters, only a few words to add concerning this sold at the shops, have repute, for their good part of the subject. Dr. Cullen states, that, effects on scrofulous constitutions and dis- in his practice, he had very little success in eases. A spirituous infusion ot gentian, into discussing incipient scrofulous tumours bv six ounces of which are put thirty-six grains, topical applications ; and that a solution of of the carbonate of soda, or the same quan- the saccharum saturni, though sometimes tity of the carbonate of ammonia, is a useful, more frequently failed. Dr. Cullen medicine highly spoken of by Richerand found the aqua ammonias acet. not more for scrofulous cases. (Nosogr. Lhir. T. 1, p. successful. “ Fomentations of every kind 184, Ed. 4.) (says he) have been frequently found to do Potassa in large doses, with mercurial harm ; and poultices seem only to hurry on frictions, is the practice lately extolled by a suppuration. 1 am doubtful if this last Mr. Farr; but it appears to me, that mer- be ever practised with advantage; forscro- cury and potassa had been repeatedly tried, fulous tumours sometimes spontaneously long before this author delivered his senti- disappear, but never after any degree of ments to the public ; and that such practice inflammation has come upon them; and cannot be entitled to be called a method therefore, poultices, which commonly in- for the eradication of the disease. (See duce inflammation, prevent that discussion Farr on Scrofula, 8vo. Lond. 1820.) of tumours, which might otherwise have According to Mr. Burns, eight or ten happened.” Even when scrofulous tumours drops of hydrosulphuret of ammonia, given have advanced towards suppuration, Dr. thrice a day, are useful in irritable strumous Cullen thought, that hastening the sponta- ulcers. The breathing of oxygen gas has neous opening, or making one with a lancet, % oeen proposed; but of this plan l know was hurtful. nothing from experience, and, as it now With respect to ulcers, Dr. Cullen re makes less noise in the world than formerly, marks, that escharotic preparations, of either 1 conclude that either its usefulness has been mercury, or copper, have been sometimes exaggerated, or the difficulty of the practice useful in bringing on a proper suppuration, is too great to allow of its extensive adop- and thereby disposing the ulcers to heal ; lion. but they have seldom succeeded, and more The sentiments of Dr. Cullen are decided- commonly, they have caused the ulcer * 4B /vSCBOFULA. spread more. The escharotic, from which Cullen saw most benefit result, is burnt alum, mixed with some mild ointment. But this celebrated writer gives the prefer- ence to keeping the sores continually co- vered with linen wet with cold water in the daytime, and some ointment or plaster at night. Cullen says, that he usually found sea-water too irritating, and no mineral water better than common water. ( First Lines of the Pract. of Physic , Vol. 4.) Formerly, the extirpation of scrofulous tumours was advised ; but this method is now considered as being, for the most part, injudicious and unnecessary, with the ex- ception of diseased joints, and a few other parts, which frequently require being am- putated for the sake of saving the patient’s fife. Certainly, no particular danger (gene- rally speaking) would attend cutting out scrofulous glands and tumours; the objec- tions to the plan are founded on the pain of the operation ; on the number of such glands frequently diseased ; on their often subsiding, either spontaneously, or by surgi- cal treatment ; on the operation doing no good to the general affection of the system, &x. When, however, a scrofulous testicle, breast, or joint, seriously impairs the health, and endangers life, the very existence of the patient demands the immediate removal of the diseased part. W iseman relates, that he was in the habit of cutting out scrofulous glands and tumours with great success ; but for reasons already alleged, most of the moderns think such operations in general at least unnecessary. Caustics have been employed for the same purpose, instead of the knife ; but, as they effect the object in view less certainly, more painfully and tediously, and cause extensive ulcers, they are disused by all th£ best surgeons of the present day. Some authors have advised making issues, and keeping them open, in order to prevent any ill effects from healing scrofulous ulcers. Issues are certainly quite unnecessary for any purpose of this kind ; but they are emi- nently useful as a part of the local treatment of scrofulous joints and abscesses, as we have more particularly explained in the ar- ticles Joints , Lumbar Abscess , and Vertebra. Mr. Burns notices, that issues have hither- to been chiefly used in diseases of the bones and joints ; hut he adds, that it is reasonable to suppose that they ought likewise to be use- ful in the cure of enlargements of the glands, and other scrofulous tumours, if inserted in the immediate vicinity of the part. The only objection to their use is the scar which they leave, and which, in certain situations, one would particularly wish to avoid. When the tumour is thickly covered with the in- teguments, the issue may be made directly over it, and kept open with the savine oint- ment. In other cases, a small pea issue or seton may be inserted by the side of the tumour. This method would be objection- able, for scrofulous glands in the neck, in consequence of the scar; but it might be employed when the mamma is disused. (Dissertations on Inflammation, Vol. 2.) The late Mr. Crowther used to apply blisters to scrofulous swellings, and maintain a dis- charge from the part. And a more modern practice is that of producingjj irritation of the integuments, covering tumours and abscesses, by means of the tartar emetic ointment. ( Alibert Nosol. Naturtlle, p. 449 ; Goodlad on Diseases of the Absorbents, p. 162, fyc.) Preparations of lead; cloths dipped in cold water, sea-water, or weak vegetable acids ; aether ; sea-salt mixed with bile ; the linimentum camphorae ; a mixture of aether and the linimentum opiatum ; and hemlock poultices ; form a long list of applications, which have been employed for scrofulous tumours. According to Mr. Burns, moderate pres- sure, by means of adhesive plaster, con- joined with the application of cold water, is one of the best plans of treating mild scrofulous ulcers, when their situation ad- mits of it. In other cases, he recommends applying a powder, five parts of which consist of cerussa acetata, and the sixth of burnt alum. A piece of dry lint is next to be applied, and a compress, with such pres- sure as can be used. Benefit occasionally results from dipping the compress in cold water. The ceratum e lapid. calamin. is a good common dressing, when it is wished not to interfere much with the progress of the ulcer. The ung. hydrarg. nitrat. rub. and the ung. hydrarg. nitrat. are the best stimu- lating ointments. Poultices of bread and sea-water; solutions of alum, cuprum vi- triolatum, and the hydrarg. mur. ; solutions of the nitrates of copper, bismuth, and silver ; the recent leaves of the wood-sorrel bruised ; lint dipped in lemon-juice, or vinegar and water , are among the applica- tions to common scrofulous ulcers. For irritable sores, diluted hydrosulphuret of ammonia ; ointments containing opium ; carrot and hemlock poultices ; a solution ot opium; and carbonic acid gas; are com- monly recommended.' The following are Mr. Russell’s sentiments respecting the treatment of scrofulous ul* cers : “ Scrofulous complaints in general do not agree well with stimulant applications, la the treatment of scrofulous ulcers, under the ordinary circumstances ot complaint, the simplest and mildest dressings answer best. When the patients are using a course of sea-bathing, it is usual to wash the sores with sea-water, over and above the momen- tary application of the sea-water during the immersion of the whole body. Cold spring- water is likewise a favourite application with many practitioners; and from much obser- vation, it appears that the operation of cold is well suited to counteract the slate of in- flammation, which accompanies scrofulous sores. Preparations of lead are, upon the whole, very convenient and useful applica- cations, provided the solutions be used in a state of sufficient dilution to prevent irrita- tion Liquid applications are applied by means of wet linen, which is renewed whenever it dries, so that the suiface of the sore may be kept constantly moist when un- der this course of management. Upon the same principle, simple ointment and Gou- lard’s cerate, furnish the best dressing in ordinary cases. “ Scrofulous congestions, of a solid na- ture, in the more external parts of the body, are little adapted to the practice of local bleeding, unless they be attended with symptoms of inflammation ; but as some degree of inflammation is, in general, pre- sent during the incipient stage, it may be prudent to employ local bleeding in modera- tion at the commencement of the attack, although there may be no indication to per- sist in the practice, after the complaint has advanced farther in its progress. If, how- ever, these congestions are more of an indo- lent nature, unaccompanied with heat or pain, there is no benefit to be expected from the local detraction of blood ; warm fo- mentations, together with the use of stimu- lants, and a repetition of blisters, are the most serviceable class of remedies : such cases, too, are the best adapted to the use of friction as a discutient. Friction, indeed, has long been employed for this purpose ; but, of late years, it has been introduced to an extent, and with an effect, far beyond the experience of all former practice. As yet it has been circumscribed to the prac- tice of a very few individuals, with whom it is said to have performed very great cures ; and if, upon the test of more extensive ex- perience, it is found to answer its present high character, I shall consider the use of repeated frictions to be one of the most valu- able improvements which has been introdu- ced into practice in modern times. The safety and simplicity of the practice recom- mend it very strongly to favour, though I am afraid they are the very circumstances which retard its adoption by the public in general. I only regret that I do not feel myself entitled to give a decided opinion upon the subject from my ow n experience, though I have known some instances of successful cures; but the reports of success are so numerous and so well supported, that I am inclined to think very favourably of the practice. u There is no substance interposed be- tween the surface of the swelling and the hand of the person who administers the fric- tion, excepting a little flour, to prevent the abrasion of the skin. The friction is applied regularly two or three hours every day, with great celerity, the hand being made to move to and fro one hundred and twenty times in a minute, and the course may require to be continued, without interruption, for some months.’' (See Russell on Scrofula.) I shall not enlarge upon this endless sub- ject, which still stands in need of elucida- tion as much as any disease that can be in- stanced- The scrofulous affections of the joints are explained in Joints ; Bronchocele ; Lumbar Abscess ; Spina bifida; and Vertebras, are other articles, containing matter con- nected with the preceding observations. The reader may consult Wiseman's Chi- rurgical Treatises. J. Brown , Adenochoira- dtlogia , or an anatomick-chirurgical Treatise of Glandules and Strumals , or King's Evil Swellings , together with, the Royal Gift of Healing , or Cure thereof by contact , or impo- sition of hands, fyc. 8i>o. Lend. 1684. Wm , Clowes , A right f rule full and approved Trea- tise, for the Artificial Cure of the Struma, or Evil, cured by Kings and Queens of England , 4 to. Lond. 1602. Cullen's First Lines of the Practice of Physic , Vol. 4. Feme on the King's Evil. Cfieyne on the King's Evil. R. Russell, A Dissertation on the Use of Sea- Waler in the Diseases of the Glands, fyc. 8 vo. Lond. 1769. B. Bell's Surgery, Vol. 5. B. Bell on Ulcers. Tumor Strumosus Colli post vomitorium imminutus. 8 vo. ( Weikard , Collect. 88.) Kirkland's Medical Surgery, Vol. 2. J. Morley, Essay on the Nature and Cure of Scrofulous Disorders, <^c. New Ed. 8 vo. Lond. 1778. While on the Struma, Edit. 2, 1 794. P . Lalonette, Traite des Scrophules, fyc, Paris, 1780. A. G. Kort urn's Comment, dc Vilio Scrophuloso , in 2 Vol. 4 to. Lemgovice, 1789. R. Hamilton, Observations on Scrofu- lous Affection, fyc. 8 vo. Lond. 1791. London Med. Obs and Inq. Vol. 1. 5. T. Soemmer ring, De Morbis Vasorum Absorbentium Cor- poris Humani. 8 vo. Traj. 1795. C. W. Hufeland, Ueber die Natur, fyc. dtr Skrophel - krankheit. Svo. Jena. 1795. Dissertations on Inflammation, by John Burns , Vol. 2. M. Underwood, Treatise upon Ulcers, <^c. with. Hints on a Successful Method of treating some Scrofulous Tumours, fyc Svo. Lond. 1785, Crowther's Obs. on the Disease of the Joints , commonly called White Swelling ; with re- marks on Caries , Necrosis, and Scrofulous Abscesses, fyc. Edit. 2, 1808. A Treatise on, Scrofula , by James Russell, Svo. Edinburgh , 1808. Lectures on Inflammation by John Thomson, M. D. p. 130, etseq. p 155— 191* c. Edinb. 1813. This work contains as good and as rational an account of the subject as any book which I have examined. Wm. Good- lad, A Practical Essay on the Diseases of the Vessels and Glands of the Absorbent System, Svo. Lond. 1814. G. Henning, A Critical Inquiry into the Pathology of Scrofula, Svo, Lond. 1815. Richerand, Nosographie Chirj T. 1, p. 165, etseq. Edit. 4. Delpech , Precis EUmentaire des Maladies, Chir. T. 3 ,p. 617, fyc. Paris, 1816. Lassus, Pathologie Chir. T 2, p. 383, fyc. Edit. 1809. Callisen , Sys - tem a Chirurgice Hodiernce, Vol. 2, p. 113 t Hafnits, 1800. Boyer , Trait6 des Maladies Chir. T 2, p. 414, fyc. Paris, 1814. Ciu Brown, Treatise on Scrofulous Diseases, show- ing the good Effects of factitious Airs. Svo. Lond. 1798. Baume, Traite sur It vice Scro - phuleux, Svo. Paris, 1808. J. Brandish , Obs. on the use of caustic alkali in Scrofula, and other chronic Diseases, Svo. Lond. 1811. C\ Armstrong, Essay on Scrofula, in which an account of the Effects of the Carbonas Ammo- nias is submitted to the Profession , Svo. Lond. 1812. W . Lambe, Inquiry into the origin , ijc. of Constitutional Disorders , particularly Scro - SCROTUM. 416. fala, Consumption^ Cancer, tyc.8vo. Lond. 1805. Also Additional Reports on the Effects of a peculiar Regimen in cases of Cancer, Scrofu- la, fyc. 8 vo. Lond. 1815. R. Carmichael , Essay on the Nature and Cure of Scrofula, and a demonstration of its origin from Disor- der of Digestive Organs, 8 vo. Dubl. J. Rab- ben, De Prcecipuis Causis Mali Scrofulosi cjusque Remediis efficacissimis commentatio, 12 mo. Goth. 1817. Alibert, Nosologie Natu- relle, p. 448, fol. Paris, 1820. Did. des Sciences Med. T. 50, art. Scrofules, 8vo. Paris, 1820. E. A. Lloyd on the Nature and Treat- ment of Scrofula, 8vo Lond. 1821. SCROTOCE'LE. (from Scrotum, and ma», a tumour.) A rupture or hernia in the scrotum. SCROTUM, CANCER OF. ( Chimney- sweeper's Cancer. The soot-wart .) Mr. Pott gives the following account of this peculiar disorder. u It is a disease which always makes its first attack on, and its first appearance in, the inferior part of the scrotum ; where it produces a superficial, painful, ragged, ill- looking sore, with hard and rising edges ; the trade call it the soot-wart. I never saw it under the age of puberty, which is, I sup- pose, one reason why it is generally taken, both by patient and surgeon, for venereal, and being treated with mercurials, is thereby soon and much exasperated : in no great length of time, it pervades the skin, dartos, and membranes of the scrotum, and seizes the testicle, which it enlarges, hardens, and renders truly and thoroughly distempered ; from whence it makes its way up the sper- matic process into the abdomen, most fre- quently indurating and spoiling the inguinal glands : when arrived within the abdomen, it affects some of the viscera, and then very soon becomes painfully destructive. “ Other people, besides chimney-sweep- ers, (says Pott) have cancers of the same part ; and so have others, besides lead- workers, the Poictou colic, and the conse- quent paralysis : but it is nevertheless a dis- ease to which they are peculiarly liable ; and so are chimney-sweepers to the cancer of the scrotum and testicles. “ If there be any chance of putting a stop to, or preventing this mischief, it must be by the immediate removal of the part affect- ed ; I mean that part of the scrotum where the sore is ; for if it be suffered to remain until the virus has seized the testicle, it is generally too late even for castration. I have many times made the experiment; but though the sores, after such operation, have, in some instances, healed kindly, and the patients have gone from the hospital seem- ingly well, yet, in the space of a few months, it has generally happened that they have returned, either with the same disease in the other testicle, or in the glands of the groin, or with such wan complexions, such pale leaden countenances, such a total loss of strength, and such frequent and acute inter- nal pains, as have sufficiently proved a dis- eased state of some of the viscera, and which have soon been followed by a painful death. “ If extirpation ever bids fair for the cure of a cancer, it seems to be in this case ; but then the operation should be immediate; and before the habit is tainted. The disease, in these people, seems to derive its origin from a lodgment of soot in the rugae of the scrotum, and at first not to be a disease of the habit. In other cases of a cancerous nature, in which the habit is too frequently concerned, we have not often so fair a pros- pect of success by the removal of the dis- tempered part ; and are obliged to be con- tent with means which I wish I could say were truly palliative ; but here the subjects are young, in general in good health, at least at first ; the disease brought on them by their occupation, and in all probability local ; which last circumstance may, I think, be fairly presumed from its always seizing the same part : all this makes it (at first) a very different case from a cancer which appears in an elderly man, whose fluids are become acrimonious from time, as well as other causes ; or from the same kind of complaint in women who have ceased to menstruate. But be all this as it may, the scrotum is no vital organ, nor can the loss of a part of it ever be attended with any, the smallest degree of inconvenience ; and if life can be preserved by the removal of all that portion that is distempered, it will be a very good and easy composition ; for when the disease has got head, it is rapid in its progress, painful in all its attacks, and most certainly destructive in its event.” (PoH s Works, Vol. 3. See also W. Simmons’s Cases and Obs. on Lithotomy, to which are added Obs. on Chimney-sweeper's Cancer, 8vo Manchester, 1808.) SCROTUM. Sarcomatous Thickening and. Enlargement of. The investigations of Ba- ron Larrey lead him to believe, that cases of enormous growth of the scrotum are ende- mial in warm countries, or, at least, that they are seldom observed in cold climates since most of the examples which have been seen in Europe came from Asia and Africa. The scrotal tumour of Delacroix, formerly minister of externa! relations, says Larrey, is perhaps the only well-authenticated in- stance of the origin of such a disease in our own climate ; and it was also much smaller than the instances related in the Epheme- rides German, for the year 1692, in the surgical writings of Dionis, in the 9th vol. of the Bibliotheque de M6decine, and those which Larrey was surprised to meet with in Egypt. The smallest of these latter, after they had attained their full size, weighed more than 25 kilograms (between 60 and 70 pounds.) Several cases of this curious disease are recorded by other writers, particularly by Dr. Cheston, Dr. Titley, and the celebrated Sandifort. I lately saw in Mr. AbernethyV. museum, a considerable fleshy substance, which was a portion of diseased scrotum. In the cases which Larrey had an oppor- tunity of seeing in Egypt, the fleshy mass, into which the scrotum was converted, was broad below, and suspended from the pube* A ETON 417 by a sort ot peuicle. “ Externally, (as Lar- >'ey observes) the tumour presents rugosi- ties of different sizes, separated by particu- lar lines or sinuses, to which the mucous cryptae and roots of the hairs correspond. Upon a large portion of its surface, espe- cially when the case is of long standing, yel- lowish scaly crusts are always seen, the detachment of which constantly leaves so many small herpetic ulcers, which emit an ichorous discharge. The tumour is indolent and hard at some points, but softish at others. It may be handled, and pressed in different directions, without the least pain. The patient is only incommoded by its weight, and the impediment which it causes to his walking well. Hence he is necessi- tated to employ a suspensory bandage. In consequence of the situation of the urethra, the urine dribbles over the swelling; but without causing any excoriation.” Inmost of the cases seen by Larrey, the spermatic chord and testicles were in the natural state, situated at the sides and at the root of the swelling. The spermatic vessels, however, are somewhat enlarged and elongated. All the patients were likewise more or less affected with elephantiasis. Baron Larrey attempts to explain the cau- ses of the complaint in Egypt, but, as I think, without any degree of success. As the af- fection is seldom seen in old countries, cli- mate has certainly a chief effect. Employ- ments w hich keep persons a good deal in a sitting posture ; the loose breeches w r orn by the Egyptians, and the consequently pendu- lous state of the scrotum ; diseases of the humours, and particularly itchy pustules on the part, an ordinary consequence of syphi- lis in that country ; bad regimen ; abuse of venery ; and the immoderate use of the warm bath ; are merely conjectures, which will not bear the test of reasoning. The enormous magnitude, w'hich this sort of disease may attain, is almost incredible. The case, recorded in the Ephemerides Ger- man, weighed about a hundred kilograms, or more than two hundred weight. Another, described by Larrey, w r as calculated to weigh about one hundred and twenty pounds, and this surgeon likewise saw in Egypt ten or twelve more instances, nearly as large, and all of the same character A very curious example, in which a simi- lar disease affected the labia pudendi in a surprising degree, is also detailed by Larrey. The woman was a native of Cairo. In the early stage of the disorder, we may try preparations of antimony combined with sudorifics ; drinks acidulated with sulphuric acid, lotions containing the same acid, or the oxymuriate of mercury, the oxyde of copper, or the muriate of ammonia. These means are to be assisted by a gradual, uni- form compression of the whole tumour. In one case, incisions and the application of caustic, proved of no service, and Larrey very properly condemns such experiments. When the disease resists every plan tried for its relief, and its increase renders the pa- tient’s life irksome, and vyretched, the extir- ■Vqt. If 53 pation ot the turnout with a knife becomes proper. In this proceeding, the chief skill consists in doing no injury to the spermatic chords and testicles, which are generally perfectly sound. As the substance of the swelling is uQt furnished with large vessels, the hemorrhage need not be feared. Care must also be taken not to injure the corpora cavernosa penis, and the urethra. After the operation, the skin is to be brought over the exposed testicles, as much as possible, with adhesive plaster and a bandage. M. Delonn.es successfully removed the dis- eased mass in the celebrated case of the French minister Delacroix, and Larrey per- formed the same operation with success, when he w as in Egypt. Dr. Titley, of the island of St. Christopher, also cut away such a tumour, which weighed seventy pounds, and the patient, who was a negro, and also affected with elephantiasis, speedily recovered. (See Medico- Chir urgical Trans. Vol. 6, p. 73, fyc.) It is probable, that some of the cases, which occur in w arm countries, are analo- gous to the elephantiasis ; but I do not be- lieve, that the scaly incrustations, which are represented by Larrey as occurring in the cases which he saw in Egypt, have been always noticed in the instances which have taken place in colder countries. Nor, in- deed, did they take place in the instance re- corded by Dr. Titley, the surface of the tu- mour having been quite smooth. (/Larrey, Mimoires de Chirurgie Militaire , T. 2. p. 110, et seq. Richerand JVosograpliie Chir. T.4,p. 314, fy-c. Edit. 4. Jllso Delonnes ’ Memoir. Dr. Cheston's Case , &c. Med. Chir. Trans. Vol. 6.) SEARCHING. The operation of intro- ducing a metallic instrument, through the urethra into the bladder, for the purpose of ascertaining whether the patient has a stone or not. See Sounding. SETON. ( Setaceum , from seta , a bristle, because horse- hairs were formerly used for keeping open the w r ound.) A kind of issue. It is usually made by means of a particular needle, which is of various breadths, from half an inch to a full inch. The needle is commonly a little curved, but, if straight, it would be better calculated for the purpose. From the point to its broadest part, it is dou- ble edged, and behind it has a transverse eye, through which a skein of thread or silk, of exactly the same breadth as the needle, is placed. A fold of skin is to be pinched up at the part where the seton is designed to be made, and the needle is to be pushed through it, together with the skein of thread, which is first dipped in sweet oil. The instrument is not to be introduced too low into the base of the fold, nor too high, near its edge. In the first case, the muscles, and parts which ought to be avoided, might be wounded ; in the second, the interspace between the tw r o wounds would be very narrow, and the se- ton soon make its way through it. When no seton needle is at hand, the fold of the skin may be punctured with a lancet. oKrlli 418 and the skein ot thread intuniuced by means of an eye-probe. A seton may be applied almost to any part of the surface of the body, ■ when circumstances require it; but one of its openings should always be made lower than the other that the matter may readily flow out. The skein of thread is to remain untouched for a few days after the operation, until the suppuration loosens it. Afterward the part of the thread nearest the wound is to be smeared with oil, white cerate, or any digestive ointment, and drawn under the fleshy interspace between the two wounds, and what was there before is to be cut off. The seton is to be drawn in this manner once or twice a day, according as the quan- tity of matter may require. A new skein of silk, or thread, is to be attached to the pre ceding one, as often as necessary. Care is to be taken to keep the thread on the outside of the wound well covered, and free from the discharge, which would make it stiff and hard, and apt to occasion pain and bleeding on being drawn into the wound. If the discharge should be deficient in quan- tity, powdered cantharides may be mixed with the digestive ointment. SH5 -GLES. See Herpes. SIGHT, DEFECT OF. There are per- sons, who, from their infancy, are incapable of distinguishing one colour from another. A man who was affected with this infirmity, could not distinguish green at all. Green and red appeared to him' the same. Yellow and blue be could discern very well. With regard to dark-red and dark-blue, he fre- quently made mistakes. In other respects, his vision was sound and acute. The father of this patient was afflicted with the same infirmity. The mother and one sister were free from it Another sister and two of her children had it. The patient himself had two children, who did not labour under the dis- order. (See . Phil. Trans. Vol. 68, Part 2.) Another subject, whose eyes were in other respects healthy, and whose eyesight was sharp, could not distinguish a dark-green from a dark-red. An interesting example of this curious imperfection of vision has lately been pub- lished by Dr. Nicholl, of Cowbridge. (See Med. Chir. Trans. Vol. 7, p. 477, fyc.) The subject was a healthy boy, eleven years of age, whose eyes were gray, with a yellow tinge surrounding the pupil. He never call- ed any colour green. Dark bottled green he called brown. He could distinguish light yellow ; but darker yellows and light browns- he confounded with red. Dark brown he mistook for black. Pale green be called light red; common green he termed red. Light red and pink he called light blue. Red be called by its proper name. He could distinguish blue, both dark and light. On the mother’s side the boy had some rela- tions whose sight was similarly affected. An interesting chapter on what is termed coloured vision, may be read in a modern valuable work, to which I have great plea- sure in “referring. (See War dr op's Esmys on the Morbid Anatomy of the Human Eye, Vol. 2, p. 196, 8 vo. Load. 1818.) Sometimes objects appear to the eye to be of a different colour from what they real- ly are, not because there is any thing wrong in the eye itself, but in consequence of tbe unclear and coloured light by which the ob ject is illuminated. Thus, for instance, a. bad tallow candle, which emits a yellow flame, makes every thing appear yellow When brandy is burning, all objects appear blue. In short, it is only by the light of the sun, that any object can be seen in its clear natural hue. In certain cases, the infirmity is owing to the transparent parts and hu- mours of the eye, which do not happen to be of a proper colour. Thus, persons hav- ing the jaundice in a high degree, see all things yellow, because the transparent parts of the eye are of that colour. When, in consequence of external violence applied to the eye, blood is effused, and the aqueous humour rendered red by this fluid, all ob- jects seem to the patient to be red; and white, when the aqueous humour has been made of this colour by the couching of a milky cataract. Sometimes this defect in vision is ascribable to the duration of an impression. When one has surveyed a bright-coloured object a long while, as, for example, a bright red or yellow wall, on which the sun shines, fi^at colour will often remain a good while before tbe eyes, al- though one may not be looking any more at au object of this hue. There are some eyes, which seem much disposed to retain the impression of objects, which are not very bright coloured ; but, such a disposition always betrays great weakness and irrita- bility of those organs. The most frequent cause of this defect in vision, is an irrita- tion operating upon the optic nerves, so as to produce the irritability in them, which alone makes objects appear of one colour. The seat of such irritation, according to Richter, is also most commonly in the abdo- minal viscera, and the case demands evacu- ations, tonics, and anodyne medicines. But, the disorder may also originate from other causes. The operation of bright-coloured or shining objects upon the eye, sometimes has, for a certain time afterward, the effect of making objects of diverse colours appear to be moving before the eyes. In extreme terror, or fright, things may also seem to have a different colour from their real one. The same often happens in fevers attended with delirium. A sudden exposure of the' head to cold, at a period when it was per- spiring much, in one instance, caused many coloured appearances before tbe eyes ; but, the disorder subsided in a couple of days. (Richter, A nfangsgr. der Wundarsn. B. 8, p 523.) Also a healthy eye sees a distant object with uncertainty, and error, in a room, or space, the extent, length, and breadth, of which are unknown, when the size of the object itself is unascertained, and when there are few or no other objects interve- ning at a smaller distance between the cyo SOL ski and the thing looked at. The mope nume- rous the objects are between the eye and the principal thing looked at, the more dis- tant it is made to appear; the fewer they are, the nearer it seems to be. In a coun- try covered with snow, and upon the sea, very distant objects appear to be close. The smaller an object is to the eye, in rela- tion to its known magnitude, the further off’ it seems. The errors which the eye makes, in regard to the distance of objects, also tend to deceive. But, there are certain ca- ses, in which the eye is almost entirely inca- pable of judging of the distance of objects. The first is, when the object, of which we wish to ascertain the distance, is looked at with only one eye. Hence all one-eyed persons, and persons affected with strabis- mus, are unable to judge well of the real distance of objects. However, they are only so for a certain time ; and. by practice they gradually acquire the faculty. Even when two eyes are employed, it requires some exercise, in order to enable them to judge of the right distance of objects. Per- sons, born blind, but who have their sight restored in both eyes by the operation for the cataract, are a long while incapable of judging of distances, and only obtain this power very gradually. Lastly, this infirmity is sometimes owing to an irritation affecting the optic nerves, whereby their sensibility is so altered, that distant objects make the impression upon them of near ones. In this circumstance, all objects appear to the pa- tient closer than they really are. This is the only case, which admits of being treated as a disease. The irritation, producing the disorder, is mostly seated in the abdominal viscera, and requires evacuations and such medicines as invigorate the nerves. A sup- pression of the perspiration is alleged to be sometimes a cause ( Richter , Anfangsgr. der IVundarzn. B. 3, p. 525.) A sound eye likewise does not always judge with accuracy and uniformity of the magnitude of objects. This may arise from three causes. In order to judge rightly of the size of any thing, its precise distance must be known ; for the more remote it is, the smaller will it seem to the eye. Hence, any conjecture respecting the magnitude of an object is constantly erroneous, unless the distance be ascertained. Size is invari- ably something relative. A single large ob- ject, surrounded by many small ones, always appears to be larger than it really is, et vice ' versa. An object whose magnitude is known, seems smaller than it actually is, when one has been a little previously looking at ano- ther that is still larger. Lastly, the refrac- tion of the rays of light in the eye, by which operation an object is made to appear large or small, is not always accomplished in the same degree, as the eye is not at all times equally full and distended with its humours. Hence, at one time, the same object will appear to the same eye, and at the same distance larger ; at another time smaller. Sometimes, however, the eye judges so er- roneously of the magnitude of objects, that 419 there is reason for regarding the case as an infirmity, or disease. It is for the most part owing to a defective sensibility in the nerves, caused by some species of irritation acting upon the eye, and generally seated in the gastric organs. A man, to whom every thing seemed one half smaller and nearer than it really was, was cured by means of an emetic, bark, an issue and valerian, ( Ltulin , obs.fascic.) Sometimes to the eye, under circum- stances of disease, straight lines appear ser- pentine ; perpendicular objects, sloping, things standing upright, to be inverted, &,c. All these cases are set down by Richter as depending upon a wrong sensibility of the nerves, occasioned by the effect of some irritation. The irritation, he says, may be of many kinds ; but experience proves that it is mostly seated in the gastric organs. These defects of sight may generally be cured by first exhibiting emetics and purga- tives, and afterward having recourse to re- medies for strengthening the nerves, bark, oleum animale, valerian, issues, &c. One mark of a very weak and irritable eye, is when objects, after being looked at a good while, and presenting a right appearance, begin to move, swim about, mix together, and, at length, become quite indistinguish- able. This principally happens when the objects regarded are small and strongly illuminated. Here such remedies, both general and topical, as have the effect of invigorating the nerves, are indicated. How- ever, sometimes, the infirmity is partly ow= ingtothe operation of some species of irri- tation, which will require removal, ere the tonic medicines and applications can avail. Indeed, in particular cases, the dispersion of such irritation is alone sufficient to ac complishtbe cure. Sometimes, all objects appear to the eye, as if they were in a more or less dense mist . This defect in vision is always owing either to some slight opacity of one of the humours of the eye, or to excessive debility of the optic nerves. (See Richter, Anfangsgr. da IVundarzn. B. 3, p. 521, fyc.) SINUS. — A long, .narrow, hollow track, leading from some abscess, diseased bone, &c. SOLUTIG ARGENTI NITRATI. — Ar genii nitrati 3j. Aq. distillat. ^ss M. This is a very good application for sores, which are frequently met with round the roots of the nails, both of the fingers and toes. It is also useful in herpetic affections, noli-me tangere, and several kinds of ulcers. The proportion of the argentum nitratum may be lessened, or increased, as occasion re- quires. A strong solution of this substance is a good application for destroying warts, to which it must be applied, by means of a hair-pencil. When used for sores, it is best to dip little bits of soft lint in it, lay them on the part affected, and cover them with a common pledget. SOLUTIO FERRI SULPHATIS.— ft, Ferri sulphatis ad albidinem calcinati 3j Aq. Distillat, ?viij. Misce. Has been re*- commended as an application tor sores on the nipple, and other ulcers. SOUND. An instrument, which surgeons introduce through the urethra into the blad- der, in order to discover, whether there is a stone in this viscus, or not. The sound is usually made of very highly polished steel, that it may be well calculated for Conveying to the surgeon’s fingers the sensation of any thing, against which its end may strike. It is also generally rather less curved, than a catheter, so that its extremity may be more easily inclined to the lower part ot the blad- der, where the stone is most frequently si- tuated. SOUNDING. The operation of introdu- cing the foregoing instrument. Sounds are generally introduced much in the same way as catheters, either with the concavity towards the abdomen, or the con- vexity, in which last method, it is necessary, as soon as the beak of the sound has arrived in the perineum, to bring the handle of the instrument downward by a semicircular movement to the right, while the other end is kept as much fixed as possible. This is what the French term the coup, or tour de maitre •, a plan, that is often followed at the present day, though, except in very cor- pulent subjects, it has no particular recom- mendation. When a patient is to be sounded, he is visually put into a posture very similar to that adopted in the lateral operation for the stone, with the exception that he is not bound in this position, as there is sometimes an advantage in making the patient stand up, in order that the stone may come into contact with the end of the sound. The instrument having been introduced, its ex- tremity is to be turned, and moved in every direction, when if there be a calculus, its presence will usually he indicated by the collision against the beak of the sound. Stones have sometimes been found in the bladder after death, although they could never be discovered with a sound while the patient was alive, suffering all the symptoms of the complaint. The celebrated French surgeon La Peyronie jvas thus circumstan- ced : he was so fully convinced of there being a stone in his bladder, notwithstand- ing neither he, nor any of his friends could feel it with a sound, that on bis death-bed, lie gave directions for ascertaining the fact. Hence, when the usual symptoms of a stone in the bladder continue, patients should be searched several times, before a positive opinion is delivered respecting the nature of the disease. When during the operation of sounding, all the urine has escaped from the biadder, the inner surface of this viscus comes into contact with U-e end of the sound, and such a sensation may be communicated to the surgeon’s fingers as leads him to suspect that a fungus, or some other hardish extraneous substance is con- tained in the bladder. In such cases, pa- tients have actually been cut for the stone, when no foreign body whatever was pre- sent. (See. Mtdecine Operatoire , Tom. 3, p. 127, 128, Edit. 2. See UiiiG - lomy.) SPECULUM. An instrument intended for facilitating the examination of parts, and also the performance of operations on them : thus we have specula ani, specula oculi, auris, &.c. SPHACELUS. (from to de- stroy.) Surgeons imply, by this word, com- plete mortification, which is mostly prece- ded by a stage of the disorder, termed gan- grene. See Mortification. SPICA. (from rv&yyc, an ear of corn.) A name, given to a kind of bandage, in consequence of its turns being thought to resemble the rows of an ear of corn. In order to apply the spica bandage to the shoulder, the margins of the axillae must first be protected from the effects of the pressure, by means of soft compresses, and the end of a common roller is then to be placed under the opposite arm-pit. After conveying the bandage backward, obliquely over the scapulai, the surgeon is to bring it forward over the injured shoulder. The roller is next to descend under the arm-pit, then be carried upward again, and made to cross on the deltoid muscle. It is now to be carried obliquely over the front of the chest, and under the opposite arm-pit, where the end of it is to be pinned, or stitched. The bandage is next to pass across the back, over the part of the roller previously applied in this situation, and is to be conveyed round the head of the os brachii, so as to form a turn, or doloire, with the first circle of the roller. Three or four doloires, or turns, each of which covers about one-third of the preceding one, are to be made, and then the upper part of the arm is to be once surrounded with a plain circle of the ban dage. This last circular application leaves between it and the cross previously made, a triangular equilateral space, technically named by writers geranis. The roller is now be to carried upward in a spiral manner ; its head is to be brought to the opposite arm- pit, and the application of the whole con- cludes with a few turns round the body. The bandage is to be fastened with pins at. the place where it commenced. In applying the spica inguinis , the end of the roller is to be placed on the spine of the os ilium, ot the affected side. The ban- dage is then to be carried obliquely over the groin, and under the perinaeum. Then it is to pass over the back of the thigh, and next forward, so as to cross the part pre- viously applied on the front of the groin The application is continued by carrying the roller over the pubes, over the opposite os ilium, and next round the body above the buttocks. The bandage thus returns to the place where it began. Its application is completed by making a few turns, like the. preceding ones, and lastly, a few circles round the body, SPINA BIFIDA, (i. e. the Cloven Spine.) Hydro-Rachitis. A disease, attended with an incomplete state of some of the verte- brae, and a fluid swelling, which is most coni' SPINA BIFIDA. 421 in only situated over the lower lumbar verte- tebrai, sometimes over the dorsal and cervi- cal ones, and in some instances, over the os sacrum. The same name has also been given to an analogous tumour, which sometimes occurs on children’s heads, attended with an imperfect, ossification of a part of the crani- um. The malformation of the spine seems to consist in a deficiency of one or more of the spinous processes. Sometimes, indeed, these processes are wanting the whole length of the vertebral column, as was seen in the case reported by Fieliz. (See Richter’s Ckir. Bibl. B 9, p. 185.) The Arabians, who first treated of this disease, erroneously imputed the deficiency of one, or more of the spinous processes to the tumour, while it is well known, that the incomplete state of the affected verte- brae is a congenital malformation, and that the swelling is only an effect. In fact, the tumour generally becomes larger and larger, the longer it continues. The spina bifida may be regarded as an affliction only met with in children : few. very few, live to the adult age with this incurable affection. Warner, however, has related a case, in which the patient lived till he was twenty. (Cases in Surgery, p. 134. Edit. 4.) As I have remarked, the swelling is most frequently situated towards the lower part of the spinal canal, particularly at the place where the lumbar vertebrae join the sacrum. The fluid which it contains resembles serum, being somewhat more liquid than the white of egg, and, like the latter, frequently coa- gulable. It is in general limpid and colour- less; but, occasionally, it is turbid, and tinged w ith blood. On pressing the tumour, a fluctuation is very perceptible, and a pre- ternatural space may also be felt existing between some of the spinous processes. The fluid is contained in a kind of cyst, which is composed of the continuation of the dura mater, investing the spinal canal, and is usually closely adherent to the integuments. According to Morgagni, spina bifida is mostly attended with hydrocephalus, and the enlargement of the head has been known to undergo a considerable diminution after the tumour of the spine had casually burst. (De Sed. et Cans. Morb. Epist. 7. art. 9. Epkern. Cur. Nat. Dtcad. 3, Art. 1, Decad. 2. Art. 2.) The fluid which was lodged in the lateral ventricles, and third ventricle, passed into the fourth, through the aqua- ductus Sylvii, ruptured the calamus scripto- rius, and thus passed into the spinal canal. Spinas bifida? usually occur on the lower part of the spine ; but they occasionally take place on the cervical vertebrae, where the tumours have the same characteristic marks as those near the sacrum. Many facts recorded by lii/ysch, in his Anatomical Observations, confirm the preceding account. The present affliction is one of a most incurable nature ; for, w’ith the exception of one case mentioned by Morgagni, (De Sed. et Cause Morb. Epist. 12, art. 9,) a second, recorded by Keilmann, { Prodrom . Act. Havn. p. 136.) and two or three others more re- cently published by Sir Astt^v Cooper, there is not, I believe, in all the records of medi cine, or surgery, any case, which either got w'ell of itself, or was benefited by any mode of treatment. Opening the tumour, either with caustics, or cutting instruments, has generally only tended to hasten the fatal event of the disease. Death soon follows an operation of this kind, and sometimes in- stantly. Tulpius observes on this subject; quam calarnitateyn si quidem reformides , chi 7-urge, cave sis iw provide aperias quod tarn, facile occidit hominem. (Observ. Med.) Bui whether the tumour he opened or notj still the disease is one of the most fatal, to which children are exposed. When afflicted with it, they very seldom live till three years of age : but after lingering several months from their birth, suddenly die. It has been said, that children with spina bifida always have their legs in a paralytic state However, this is not true ; for the largest spina? bifidia? I ever saw, was under my friend .Vir. Maul, of Southampton, and was unattended with any weakness of the legs Indeed the child was, to all appearance, as stout, healthy, and full of play as possible. The fatal event, how ever, took place after a time, as usual ; and if my memory does not fail me, Mr. Maul noticed, that a little before death, a remarkable subsidence of, the swelling occurred, though it never burst ex ternally It is a fact notwithstanding, that many infants with spina bifida, have paralytic lei:s, and can neither retain their feces nor urine. If we draw our inferences from the cases and remarks offered by almost every writer on spina bifida, we must regard all attempts to cure the disorder, by making any kind of opening, as exceedingly perilous, if not posi- tively fatal. It is to be observed at the same time, that some practitioners have not alto- gether abandoned the idea of devising a mode of accomplishing a cure, at least in a few instances. Mr. B. Bell says, that if the tumour proceeded from disease of the spinal marrow or its membranes, no means of cure will probably ever be discovered. But if the the deficiency in the spinous processes of the vertebra?, with which the disease is always accompanied, is not an effect of the com- plaint as was commonly imagined, and if the collection of fluid takes place from the want of resistance in the dura mater, in conse- quence of the imperfection of the bones, Mr. B. Bf-ll questions, whether it would not be proper io tie the base of the tumom with a ligature, not merely with a view of remo- ving the swelling, but in order to resist the propulsion of the cyst further outward. Mr Beil acknowledges, that the event of this practice must be considered as very dubious; but expresses his w ish to devise any plan , that would afford even the least chance of success, in a case which must terminate in an unfavourable manner. Mr. Bell men- tioned the design of putting the method to a trial, on the first opportunity, and after the detachment of the swelling on the outside of the ligature, he intended to keep a soft' com- press on the part with a proper bandage. I do not know whether this gentleman ever SPINA BIFIDA 422 pat file above scheme in practice ; but sup- pose not. It is properly objected to by the author of the article Spina Bifida, in the En- cyclopedic Mithodiquc , Parl.Chir. because the disease is often attended w ith other mischief of the spinal marrow and brain, and the base of the swelling is almost always too large to admit of being tied at all, or not without hazard of dangerous consequences. Richter has proposed the trial of two caus- tic issues at a little distance from the swell- ing ; but I am not acquainted with any facts in favour of this practice. Mr. Abernethy first suggested the trial of a gentle degree of pressure on the tumour from its commencement, with the view of producing absorption of the fluid, and pre- venting the distention of the unsupported dura mater. Were the fluid to continue to increase, notwithstanding such pressure, Mr. Abernethy thinks, that as death would be inevitable on the tumour bursting, it might be vindicable to let out the fluid by means of a puncture made with a finely-cutting in- strument. The wound is to be immediately afterward closed with sticking plaster, and if possible, healed. Another accumulation is then to be prevented if practicable, with bandages and topical applications. Mr. Abernethy actually made the experiment of a puncture in one hopeless instance, in which, indeed, the swelling had previously just begun to burst. The puncture was re- peated every lourth day for six weeks, during which time the child’s health continued un- affected. The wounds were regularly heal- ed ; but the plaster having been rubbed off one of the punctures, the part ulcerated, the opening could not be healed, t tie discharge, from having been of an aqueous quality, be- came purulent, and death ensued. This case was also unfavourable for the trial of the method, as the integuments covering the tumour w ere diseased, and had no disposi- tion to contract. . The annexed case, published by Sir Ast- ley Cooper, will serve to show the benefit which may be derived from pressure. “ James Applebee, Baldwin-Street, Old- Street, was born on the 19ih of May, 1807, and his mother, immediately after his birth, observed a round and transparent tumour on the loins, of the size of a large walnut. On the 22d of June, 1807, the child was brought to my house, and I found, that although it bad spina bifida, the head was not unusually large ; and the motions of its legs were per- fect ; and its stools and urine were dischar- ged naturally. I applied a roller around the child’s waist, so as to compress the tumour, being induced to do so from considering it as a species of hernia, and 'hat the deficien- cy of the spine might be compensated for by external pressure. The pressure made by the roller, had no unpleasant influence on its voluntary powers; its stools and urine con- tinued to be properly discharged, but the mother thought that the child was occasion- ally convulsed. At the end of a week, a piece ol plaster of Paris, somewhat hollow ed, and that hollow partly filled with a piece of. loose lint, was placed upon tne surface of the tumour: a strap of adhesive plaster vyas applied to prevent its changing its situation, and a roller w r as carried around the waist, to bind the plaster of Paris firmly upon the back, and to compress the tumour as much as the child could bear. This treatment was con tinned until the month of October, during which time, the tumour was examined about three times a week, and the mother reported that the child was occasionally convulsed. When the child was five months old, a truss was applied, similar in form to that which i sometimes use tor umbilical hernia in chil- dren, and this has been contained ever since. At the age of fifteen months, it be- gan to make use of its limbs ; it could crawl along a passage, and up two pair of stairs At eighteen months, by some accident, the truss slipped from the tumour, which had become of the size of a small orange, and the mother observed, when it was reduced, that the child appeared in some degree dull ; and this was always the case if the truss was left off fora few minutes, and then reapplied. At fifteen months he began to talk ; and at two years of age, he could walk alone. He now goes to school, runs, jumps, and plays about as other children. His powers of mind do not appear to differ from those of other children. His memory is retentive, and he learns with facility. He had the measles and small-pox in the first year, and the hooping-cough at three years. His head previously and subsequently to the bones closing, has preserved a due proportion to other parts of the body. The tumour is kept by the truss entirely within the channel of the spine ; but when the truss is removed, it soon becomes of the size of half a small orange, it is therefore necessary, that the use of the truss should be continued. When the truss is removed, the finger can be readily pressed through the tumour into the channel of the spine.” {Med. Chit. Trans. Vol.2,p 323 4-c.) The next case, also published by Sir Astley Cooper, will prove, that spinse bifi- da? may sometimes be treated on another plan, so as to accomplish a permanent cure “January 21sf, 1809, Mrs. Little of No 27 Limehouse Causeway, brought to my house her son, aged ten weeks, who was the subject of spina bifida. The tumour was situated on the loins ; it was soft, elas- tic, and transparent ; and its size about as large as a billiard ball when cut in half; his legs were perfectly sensible, and his urine and feces were under the power of the will, &,c. Having endeavoured to push the water contained iu the tumour, into the channel of the spine, and finding that if the whole was returned, the pressure would be too great upon the brain ; I thought it a fair opportunity of trying what would be the effect of evacuating the swelling by means of a very fine pointed instrument, and by subsequent pressure to bring it into the state of the spina bifida in Applebee’s child. 1 therefore immediately punctured the tumour with a needle, and drew off about two SPhN'A VENTOSA, ounces ot water. Un Hie 25th January, finding the tumour as large as before it bad been punctured, I opened it again, and in the same manner, and discharged about four ounces of fluid. The child cried when the fluid was evacuated, but not whilst it was passing off. On January 28th, the tu- mour was ns large as at first ; I opened it again, and discharged the fluid. A roller was applied over the tumour, and around the abdomen. February 1st, it was again pricked, and two ounces of fluid discharged. On the 4tb, three ounces of fluid were dis- charged. On the 9th, the same quantity of fluid was evacuated as on the 4th ; but in- stead of its being perfectly clear as at first, it was now sanious, and it had been gradu- ally becoming so in the three former opera- tions. On the 13th, the same quantity of fluid was taken away; a flannel roller was applied over the tumour and around the ab- domen ; a piece of pasteboard was placed upon the flannel roller over the tumour, and another roller over the pasteboard to confine it. On the 17th, three ounces of fluid, of a more limpid kind, were discharged the pasteboard was again applied: On the 27th, the surface of the tumour inflamed ; the fluid not more than half its former quantity, was mixed with coagulable lymph, and the child suffering considerable constitutional irrita- tion, was ordered calomel and scaromony, and the rollers were discontinued. On the 26th, the tumour was not more than a quar- ter of its former size ; it felt solid ; the inte- guments were thickened, and it had all the appearance of having undergone the adhe- sive inflammation. On the 28ib, it was still more reduced in size, and felt solid. March 8th, the swelling was very much lessened ; the skin over it thickened and wrinkled ; a roller was again had recourse to a card was put over the tumour, and a second roller was applied. March 1 1 tb, the tumour was much reduced ; the skin covering it was a little ulcerated. On thq 15th, it was flat, but still a little ulcerated. On the 27ih, the effused coagulable lymph was considerably reduced in quantity, and of a very firm consistence. the 2d of May, nothing more than a loose pendulous bag of skin remained, and the child appearing to be perfectly well, the bandage was soon left off. On December the 18lh, the child was attacked with the small-pox, ar.d went well through the dis- ease. The skin now hangs flaccid from the basis of the sacrum ; its centre is drawn to the spine, to which it is united, and thus the appearance of the navel is produced in the tumour by retraction of the skin. The pricks of the needles are very obvious, forming slight indentations.” (See Med. Chir. Trans. Vol. 2, p. 326—329.) At the time when Sir A. Cooper trans- mitted this case to the Medical and Chirur- gical Society, it had been under bis observa- tion two years and a half. 'I he first of the preceding observations exemplifies the palliative treatment, adopted by the latter gentleman, and consisting of ’he application of pressure, in the manner of 423 a truss for hernia ; the second shows the radical mode of cure by puncturing the swelling from time to time with a needle, and exciting the adhesive inflammation, which, with the assistance of pressure, stops the disease altogether, that is to say, in such examples as admit of cure. Children are sometimes born with tu- mours, analogous to spinae bifidae, but situa ted on the bead. There is a deficiency of bone at some part of the skull, and through the opening a sac, composed of the dura ma ter, protrudes, covered only by the integu- ments. Mr. Earle lately met with such a swelling situated upon the occipnt of a fe male infant. The plan of repeatedly making small punctures with a common needle, dis charging the fluid, healing up the punctures and applying pressure, was tried, and fol lowed up for some time without the occur- rence of any unpleasant symptoms. Even punctures were sometimes made with an ordinary lancet ; yet the child suffered no harm from the operation, and somtf'hopes of a cure were indulged. At length, howe- ver, ulceration of the swelling took place, the child became indisposed, and rapidly sunk (See Med. Chir. Trans. Vol. 7, p. 427.) Con suit Ruyschii Obs. Anat. Warner's Cases in Surgery. B. Bell’s System of Surgery , Vol. 5. Acrel in Schwed. Abhandl. x. B. p. 291,, &pc. Murray , Opusc. 2, No. 5, et Med. Pract. Bibl. 3, p. 612. Portal Cours d'Anat, Med T. 4, p. 66. Lassus, Pathologic Chir. T. 3, p . 260, et seq. Edit. 1809. Abernethy’s Sur- gical and Physiological Essays, Part 1 and 3. T. V. Okes, An Account of Spina Bifida, with Remarks on the Method of Treatment pro posed by Mr Abernelhy, Sro. Cambridge , 1810. Encyclopedic M6lhodiqve, Part . Chir Art. Spina Bifida. Richter. Ahfangsgr. dec JVtmdarzn. B. 5, Kap. A. Cooper, Med , Chir. Trans. Vol. 2. p. 322, fyc. H. Earle , in the same work, Vol. 7, p. 427, fyc. Edinb Med. and Surg. Journ. No. 67. SPINA VENTOSA. The Arabian writers first employed this term', to express a dis- ease, in which matter formed in the interior of a bone, and afterward made its way out- ward beneath the skin. Until the matte; had escaped from within the bone, these au- thors describe the pain as being incessant and intolerable ; but that after the pus had made its way outward by fistulous openings, the pain underwent a considerable diminu- tion. The matter sometimes insinuated it- self, from the interior of the bone, into the cellular substance, so as to render it soft and flabby, though not always attended with any change of colour in the skin. The swelling had some of the appearance of emphysema. To express this state, the Arabians added the term ventosa to that of spina, which was employed, before their time, to express the nature of the pain at- tendant on the disease. (See an account of this subject in the Encyclopedic M6thodique, Part. Chir. Art. Spina' Ventosa.) The term spina ventosa has, since the time of the Arabian writers, been used by many to signify the disease named white-swelling, 424 i»ri find the former might also mean by it a simi- lar affection, though the contrary may be inferred from their account of the matter passing from the interior of the bone under the integuments, a thing which I believe never yet happened in any case of white- swellin/. Another, and perhaps a decisive argument, against the original signification of the word being the same as that of white-swelling, is, that it was not restricted to diseases of the joints and heads of the bones ; but was also applied to abscesses, which commenced in the cavities of the middle portions of the long bones, where, I need hardly observe, white -swellings never make their attack. For these reasons, many respectable au- thors have implied by the term spina vento- Mi an abscess in the interior of the bone. (See, on this subject, Lalta's System of Sur- gery, Vol. t, p. 165.) Cases of this latter kind, I know, are infinitely rare, compared with that common disorder, the white- swelling ; and, I am also certain, from the descriptions given by some authors, that *heir cases of spina ventosa were in reality instances of necrosis. But that abscesses do occur, and begin in the interior of the bones, more particularly of those of young persons, 1 have no doubt myself, both from two or three cases, which 1 remember ha- ving seen in St. Bartholomew s Hospital, and from some cases recorded by the most authentic writers. 1 cannot conceive, how- ever, that suppuration can take place to any extent within a long bone, without being followed by necrosis. . J L Petit relates, that a man, with a tu- mour on the middle of the tibia, who had been treated by him as a venereal patient, found, a fortnight afterward, that the pains which had never ceased, now began to grow more violent. The patient was feverish, his legs became red, and even painful, exter- nally. An incision was made in the situa- tion of the tumour with a view of letting out the matter which was suspected to be the occasion of the bad symptoms, and to have insinuated itself under the periosteum. The incision was of no service, and, two days afterward, the trepan was applied, by which means, a large quantity ol matter was let out. The medullary part of the bone seemed quite annihilated, and the ca- vity almost empty. Petit made three other perforations with the trepan, and cut away die intervening pieces of bone, lbe actual cautery was also used several times to de^ stroy the caries, and the patient at length got well. ( Traili des Maladies des Os, de J. L. Petit.) If any one doubt, that abscesses now and then form in the middle of the long bones, 1 must request him to consult Mr. Hey’s Practical Observations in Surgery , p 22, where he mav peruse two very inter- esting eases illustrative of what Mr. Hey calls Abscess in the Tibia with Caries. . It must be confessed, however, that these were only cases of necrosis, for which af- fection the term caries is too often inaccu- rately used. Indeed, it would appear, from 3PL tin, observations of Dr. Macartney, that a very small suppuration in the medulla is ac- companied with the beginning of those changes of the periosteum, which attend necrosis. (See Necrosis, p. 762.) For an account of spina ventosa, in the sense of white-swelling, refer to Joints. J. Pandolphinus, De Venlositalis Spince Scevissi- mo Morbo, 12 mo. Norib. 1674. A. J. van dec Meer, de Spina Ventosa, Duisb. 1 729. F. L Augustin, de Spina Ventosa Ossium, Icon. 4, 4 io Halce, 1797. F. H. Schuchardt, Annota- ta quoedam de Spina Ventosa, cum annexa singulari hujus morbi observatione , 12 mo Marburg. 1817. SP1RITUS AMMONliE COMPOSJTUS. Besides the well-known uses of this medi cine internally exhibited, its vapours are an exceedingly proper application to the eye in some cases of chronic ophthalmy. Scar- pa recommends a remedy of a similar na- ture. SPLINTS. Long thin pieces of wood, or tin, or strong pasteboard, employed for preventing the ends of broken bones from moving so as to interrupt the process by which fractures unite. These instruments are sometimes used in other cases, for the purpose of keeping limbs from moving, particularly in some kinds of dislocationsj wounds, &.c. In simple fractures of the arm, forearm, or even of the thigh, or leg, in young in- fants, it matters not whether the splints be made of wood, pasteboard, or tin. In this country, surgeons usually keep sets of splints made expressly for the leg. These are of different sizes, excavated and shaped to the part, and furnished below with apertures for the projecting malleoli. When the limb is laid upon its outside, the foot is also usu- ally supported and kept steady by the under splint, extending some distance towards the toes. Very excellent splints for the legs of young children are made of strong paste- board, accommodated in shape to the con- tour of the limb. Splints for the thigh, arm, and forearm, whether made of tin, or wood, should always be' slightly concave on the side, which is to be applied to the broken limb. They should likewise be made as thin and light, as is consistent with the neces- sary degree of strength for preventing the bro- ken bone from bending. The sets of splints, which are usedfor fractured legs and thighs in England, are frequently furnished with straps, which have a great many small perforations in them at stated distances, and can thus be easily fastened by means of little pegs for the purpose. Tapes are also sometimes em- ployed ; but they often get loose, and can- not be depended upon so well as leather straps. Pasteboard, as a material lor splints, has one advantage, viz. j when wet, it. becomes soft, and admits of being accurate- ly applied to every point of the surface of the limb: consequently, as soon as it dries and recovers its firmness again, it retains the exact shape of the part, and makes every where equal pressure on it, without incom- moding the patient, Pasteboard, however. SP 0 Si A 42a js hardiy strong and durable enough for many fractures ; nor will it answer when there is any discharge, nor when the sur- geon wishes to employ any fluid applica- tions. But, it is generally allowed, that no substance is better calculated for supporting the fractured lower jaw ; for, it is perfectly strong enough for this particular case, and if wet before being applied, it forms when dry a solid covering, most accurately corres- ponding to the shape of the jaw. Whatever may be the substance of which splints are made, they ought always to be at least as long as the fractured bone ; and, if the situation of the limb will allow, they ought, says Boyer, to extend its whole length. a For instance, (says he) for sim- ple fractures of the thighs of very young children, the pasteboard splints, which I employ, reach from the upper part of the thigh, to the lower part of the leg. Gene- rally speaking, the longer splints are, the better they fix the limb, and keep the frac- ture steady.” ( Boyer Traitd dts Mai. Chir. T. 3, p. 60.) The number of splints must depend upon their breadth, and the thickness of the limb. For the forearm, two are sufficient; for the upper arm and thigh four are often used and for the leg two, and sometimes three. In cases of fractured thighs, when the straight position is preferred, the external splint should extend from the crista of the ilium to some little distance beyond the sole of the foot ; while the inner one should reach from the upper and internal part of the thigh also beyond the sole of the foot. With respect to the anterior splint it is indif- ferent whether itonly reachesfrom the groin to the knee, or as far as the lower part of the leg. The lateral splints for a broken leg ought to be sufficiently long t6 embrace the knee, and confine the motions of the foot and ankle. When the straight posture is adopt- ed, a splint is frequently laid along the front of the leg, from the patella to the lower part of the tibia. None however can ever be required under the limb, as there the bedding itself more conveniently affords the necessary degree of support. Of all the different pieces of the appara- tus for the treatment of fractures, the splints are by far the most important and essential. Without them, indeed, it would be in vain to attempt to keep the extremities of the fracture from being displaced. As splints are generally composed of hard materials, the bad effects of their pres- sure upon the skin must always be counter- acted by placing a sufficient quantity of tow, wool, or other soft substance between them and the limb. In order to understand, however, the principles, which should guide the surgeon in the choice and application *of splints, many remarks, offered in the article i Frac- ture, must be consulted. SPONGIA PR.® PAR AT A. {Prepared Sponge; Sponge-tent.) Formed by dipping Vol, II, 54 pieces of sponge in hot melted emplastrum cerae compositum, and pressing them be- tween two iron plates. As soon as cold, the substance thus formed may be cut into pieces of any shape. It was formerly much, used for dilating small openings, for which it was well adapted, as when the wax melt- ed, the elasticity of the sponge made it ex pand and disteud the opening. However, the best modern surgeons seldom emplov it. SPONGIA USX A. {Burnt Sponge.) This is often given in the torus of lozenges, in cases of bronchocele, in which particular instances much efficacy is imputed to allow- ing the lozenges to dissolve gradually in the mouth, after putting them under the tongue. Burnt sponge is also exhibited in many scro- fulous diseases, and in cases of chronic en- largement of the prostate gland. The dose is from a scruple to a dram. STAFF. An instrument of considerable importance in the operation of lithotomy, being in fact the director for the gorget, or knife. It is made of steel, and its handle is generally rough, in order that it may be more securely held. As it is intended to be introduced through the urethra, its shape- ought to be principally determined by the natural course of that passage. The English generally employ a staff, the curvature of which forms the segment of a larger circle than that described by the curvature of o. staff used by the French practitioners. (See Roux , Voyage fait a Londres en 1S14, ou Pa- rallele de La Chirurgie Angloise , tyc. p. 319.) In other words, the French staff turns more upward than ours, as it approaches and en- ters the bladder. There may be some ad- vantage in this construction, inasmuch as it tends to make the gorget enter in the direc- tion of the long axis of the bladder; yet, a great deal more seems to me to depend upon the position in which the staff is held, than upon its shape. Lithotomists should always employ as large a staff as can be easily in- troduced, because the operation will thereby be facilitated. The groove, the most im- portant part of the staff, is of course situated upon the convexity of the curved part of the instrument, or upon that portion, which, when introduced, lies in the membranous part of the urethra, prostate gland, and the bladder. It should always be made very broad and deep, as recommended by Lan- genbeck, and Mr. Martineau. (See Lithoto- my.) The termination of the groove at the end of the instrument should be closed, so as to stop the further entrance of the gorget, and prevent the beak of the latter instrument from doing mischief. English surgeons have been justly censured by De- sault and Sabatier, for neglecting this es- sential caution ; for, certainly, the most fa- tal injury may be done by the gorget slipping beyond tbe end of the staff. (See Lithoto- my.) For ray own part, if I am more sure of any one thing in surgery, than another, it is this, that the beak of a gorget in the bladder ought never to pass out of, or be» yond the groove of the staff. STAPHYLOMA, (frouti sratpvMf a grape. oi'AMIYLOMA; 4 26 from its being thought to resemble a grape.) Is that disease of the eyeball, in which the cornea loses its natural transparency, rises above the level of the eye, and even pro- jects beyond the eyelids, in the form of an elongated, whitish, or pearl-coloured tu- mour, which is sometimes smooth, some- times uneven, and, according to Scarpa, attended with total loss of sight. However, staphyloma is either partial or total, that is to say, it affects only a part or the whole of the cornea; and in the first case, if thhat the recent staphy- loma in infants is quite compact and solid, on account of the augmented thickness of the cornea ; but he is convinced by repeated observation, that, in this very same staphy- loma, originally quite solid and compact, the cornea becomes thinner, or, at all events, is not thicker than natural, after the disease has existed a series of years in adult sub- jects, and in whom the swelling of the cor- nea has attained such a size as to protrude beyond the eyelids. The tumour, he ob- serves, is not solid throughout, except in regard to its containing, in its amplified state, the iris, the crystalline, and very often, also, a portion of the vitreous hu- mour. The cornea of infants, in its natural state, is at least twice as thick and pulpy as that of adults, and, consequently, the anterior chamber of the aqueous humour, in the former, is comparatively so contracted, to what it is in the latter, that, in infants at the breast, the cornea may be considered as in contact with the iris. To such qualities of the cornea, in child- ren of tender years, and to the natural nar- rowness of the anterior chamber of the aqueous humour, Scarpa imputes the cause why ophthalmies in infants so often pro- duce opacity and thickening of this mem- brane. The cornea swells, becomes preter- naturally thickened, and is very soon con- verted into a pointed, whitish, or pearl-co- loured tumour, without any cavity inter- nally, and either in perfect contact with, or adherent to, the iris. In the course of years, however, Scarpa remarks that this disease undergoes new modifications. For, as the whole eye enlarges with age, the iris and crystalline, from causes not sufficiently un- derstood, abandon their natural situation, and are propelled forward, nearer and nearer to the cornea; which they in time STAPHYLOMA ■distend in all its dimensions, so as to make it project beyond the eyelids, at the same time rendering it thinner in a ratio to its bulk and magnitude. Scarpa has never met with a voluminous staphyloma, projecting beyond the eyelids in adult persons, which had not originally made its first appearance in infancy ; and he has invariably found, that the thickness and density of the cornea, both in the living and dead bodies ot those who have been affected with this disease, were in an inverse ratio to the eye. Jn in- veterate cases of staphyloma, forming a large protuberance beyond the eyelids, the iris may here and there be clearly discerned through the diseased cornea, and if it be not equally manifest at all points of the tu- mour, it is because the conjunctiva exter- nally spread over the cornea forms, in con- junction with its varicose vessels on the surface of the tumour, a stratum of matter, not every where equally dense and opaque. This dense stratum of the conjunctiva, spread over the cornea, easily causes decep- tion in a staphyloma of considerable bulk. The more the tumour increases, the more the substance of the cornea seems to be- come dense and thickened ; while in reality the contrary happens ; for the augmentation in the density of the layer of the conjunc- tiva, covering the cornea, only partly sup- plies the diminution in the thickness of the latter membrane. In staphyloma, as Mr. Wardrop observes, “ the pupil is hid accord- ing to the situation and degree of the opa- city of the cornea ; but, in most cases it is altogether obliterated, and even in those, where a transparent portion of the cornea is opposite to it, the vision is much impair- ed ; for, as the eye has lost its form as an op- tical instrument, the change in its refractive power must render objects very indistinct .” {Morbid Anat. of the Eye, Vol. 1 ,p. 101.) The sclerotica is also subject to staphy- loma, that is, to a partial distention and pro- minence ?of its anterior hemisphere in the white of the eye. Scarpa never met with any tumour or prominence on the front sur- face of the sclerotica, corresponding to the white of the eye ; but in the dead subject he has met with two examples of staphyloma in the posterior hemisphere of the sclerotica. According to Mr. Travers, in the spheroidal staphyloma of the cornea, the sclerotica sometimes yields so much as greatly to in- crease the deformity. “This happens in hydropic and other degenerations of the humours. It also frequently becomes ex- tenuated, or bulged near its junction with the cornea in the amaurosis, which follows inflammation of the choroid. This protru- sion, larger or smaller, is sometimes cir- cumscribed, and in other instances diffused over a large portion of the ball. It is often seen encircling the cornea, and presenting a sacculated or pouched appearance. It has a bluish gray tint, &-c.‘’ ( Synopsis of the Diseases of the Eye, p. 130.) When in the staphyloma of the cornea, this part is affected with irremediable opa- city, Scarpa thinks that if the disease be re- cent. and in a child, the only object must be to hinder the increase Of the swelling of the cornea, the organization of which is already destroyed. The tumour must be levelled, and flattened as much as possible ; and when the swelling of the cornea is invete- rate, very large, and prominent beyond the eyelids, it is to be diminished by surgical means, so as to return within the orbit, suf- ficiently to permit the deformity of the face to be amended by the application of an ar- tificial eye. In cases of recent staphyloma, Richter used to make at the bottom of the tumour of the cornea an artificial ulcer, by repeat- edly applying the argentum nitratum, or the oxygenated muriate of antimony (butter of antimony,) and to keep the little sore open by the continued use of the same caustic, with the view of effecting a diminution of the swelling of the cornea. In this way Richter frequently succeeded in lessening staphyloma, and be one particular case he even restored the transparency of the cor- nea. Ter repetitd operalione, quarto scilicet , septimo et decimo die, ne vestigium quidem morbi die decimo-quarto superabat. Obs. Chir. Fasciculus 2. Though Scarpa has frequently attempted to cure the recent staphyloma of infants' by the above method, he has never yet met with such success, as can be at ail compared with Richter’s, either in restoring the trans- parency of the cornea, or accomplishing a diminution of the volume of the staphyloma. Having formed with the argentum nitratum a small ulcer, at the bottom of the cornea, arid kept the sore open thirty days and more, he failed in obtaining any benefit, in respect to. the diminution, much less the opacity of the cornea, in three infants, one a year and a half old, and the two others somewhat more than three, all which sub- jects had been recently attacked with sta- phyloma in one eye, in consequence of the small-pox. A violent chemosis, in a very short time produced a staphyloma in the eye of a child five years old. Scarpa made an ulcer at the bottom of the cornea, in the unorganized swollen substance of which he introduced, for a little depth, the flat part of a lancet. Scarpa kept the sore open for five weeks, with a solution of the argentum, nitratum, and he remarked that the staphy- loma became somewhat flatter, so as to lose the acute prominence which it had at its centre ; but the cornea continued, as be- fore, every where opaque. - Though Scarpa employed the same method in two otjier subjects, of about the same age, and in the same circumstances ; though he kept the ulcer open fifty days, he was never able to effect any depression or diminution cf the staphyloma; and, consequently, the point- ed, pearl-coloured projecting part of the tumour continue’d in the same state as it was before. The conical shape which the cor- nea assumes in this disease, he observes, is a characteristic symptom by which a sta- phyloma may be distinguished from a leu- coma, with total opacity of the cornea. If, also, in the course of further trials, partial benefit be found to accrue from thi c ' STAFHYtOMA 42k plan, adopted not tor the purpose of re- establishing the transparency of the cornea, but for that of merely checking and dimi- nishing the recent staphyloma in infants, still Scarpa is of opinion, that no one will be easily persuaded that the same treatment can ever prove of the least service in dimi- nishing the size of the large, inveterate staphyloma in adults ; in other words, of that which projects beyond the eyelids, and rests on the cheek. Under these circum- stances, he believes, that there is no effect- ual means of restraining the progress of the complaint, and removing the deformity, but cutting away the staphyloma, and when the place is healed, an artificial eye may be ap- plied. Celsus thus expresses himself on the sub- ject of this operation : — Curalio duplex est. Altera ad ipsas radices per medium transuere acu, duo lina ducente , deinde atlerius Uni duo capita ex superiore parte , alterius ex inferiore adslringere inter se quce paulatim secando id excidant. Altera insumma parti ejus ad len - iiculcB magnitudinem exscindere ; dtinue spo- dium , nut cadmiam inf Heart. Utrolioet au- tern facto , album ovi lana excipiendum, et im- ponendum ; posleaque vapore aquee ealidee fovendus o cuius, et ienibus medicamentis un - guendus est. De Medicina, lib. 7, cap. 6. Though, says Scarpa, the first plan, or that of the ligature, is at present abandoned, the majority of surgeons still persevere in pass- ing a needle and ligature through the lower part of the staphyloma, not for the purpose of tying or constricting the tumour, it is true, but of making a noose, in order to fix the eye conveniently, when the staphyloma is to be cut off in a circular manner. This use of a needle and ligature, which 1 observe is sanctioned by Mr. Travers, (Synopsis, fyc. p. 285,) i is strongly disapproved of by Scarpa. With regard to the second method of re- moving the staphyloma, or that of excision, Scarpa thinks that sufficient attention has not hitherto been paid to what Celsus has written on this subject. In fact, Celsus does not for- bid cutting away the staphyloma, by a circu- lar incision at its base, as is practised at the present day, but says that this operation is to be done in the centre, or conical point of the tumour, and that as much of this part of the staphyloma is to be cut away as will equal a iontil in size : In summd parte ejus ad lenticu- he magnitudinem exscindere. Scarpa remarks, that the great importance of this precept of Celsus, in regard to the successful treatment of the staphyloma, can only be duly appre- ciated by surgeons who have often had oc- casion to compare the advantages of Celsus’s doctrine, with the serious inconveniences which result from the common practice of cutting away the staphyloma circularly at its base ; and with the evils produced by a se- micircular sectioii, comprehending the scle- rotica, in Woolhouse’s manner, always fol- lowed by acute inflammation of the eyeball and eyelids, violent pains in the head, rest- lessness, spasms, copious, and somotimes gan- grenous, suppurations of the eye and eyelids. The patient being seated, Scarpa directs an assistant to support his head properly ; then taking in his hand a knife, similar to what is used in the extraction of the cata- ract, he passes the instrument completely across the staphyloma, at the distance of one line and a half, or two lines, from the centre or apex of the tumour, from the external to- wards the internal angle of the eye, and by passing the knife forward in the same direc- tion, just as is done in the extraction of the cataract, he makes a semicircular incision downwards, in the most prominent part of the tumour. Having done this, be takes hold of the segment of the staphyloma with the forceps, and turning the edge of tl\e knife upward, he completes the circular re- cision of the apex of the tumour, in such a way that the detached portion is one, two, three, or four lines in diameter, according to the size of the staphyloma. As a portion of the iris adhering to the cornea, from the very commencement of the disease, is commonly included in this section of the pointed part of the tumour, no sooner is the circular di- vision of the apex of the staphyloma made, than the crystalline, or its nucleus, issues from the eye, followed by a portion of the vitreous humour. In consequence of this evacuation, the eyeball often diminishes in such a degree, that it can be covered by the eyelids, to which Scarpa immediately ap- plies a pledget of dry lint, supported by a retentive bandage. When the eye and eyelids begin to be pain- ful, inflame, and swell, as they generally do on the fourth day, the eye is to be covered with a bread and milk poultice. When things proceed in a regular manner, the swell- ing of the eyelids subsides about the seventh or ninth day, and purulent matter is seen on the poultice, blended with the vitreous hu- mour. The matter afterward becomes thick and whitish, the patient feels great relief, and the eyeball shrinks and sinks into the orbit. At this period, on gently separating the eyelids, the conjunctiva is found swelled, and reddish, and the margin of the wound seems like a whitish circle. This is usually detached on the twelfth or fourteenth day af- ter the operation, when the edge of the sur- face, from which the staphyloma was cut, becomes red, contracts, and daily diminishes, so that at last the wound is entirely closed. There only remains in the centre of the cor- nea, for a few' days, a small fleshy promi- nence, resembling a little reddish papilla, which, after being touched a few times with the argentum nitraturn, contracts, and heals. So far, says Scarpa, are alarming symp- toms from following this operation, that in a great number of cases the surgeon is even obliged, several days afterward, to stimulate the eye on which it has been performed, in order to make it inflame, partly by leaving it a long while uncovered, and exposed to the air, partly by enlarging the circular recision, made in the centre of the staphyloma, of which another circular portion, half a line broad, is removed, in order to facilitate the more abundant discharge of the humours, and the ingress of air into the cavities ot the eye, which are so backward to inflame. An soon as inflammation has invaded tho infe STL SUL 429 tior of the eye, and suppuration has taken place, the rest of the cure regularly follows under the use of topical emollients, and is soon completed with all possible mildness. It should be particularly recollected, that Scarpa means the foregoing practice for in- veterate cases of staphyloma, where the eye- sight is totally lost, and (he projection of the diseased coruea produces serious annoyance. Under other circumstances, the method can hardiy be admissible. Among others, Dr. Vetch particularly objects to the remo- val of the apex of the tumour, as destructive of all chance of the recovery of a degree of vision ; a consideration, however, which would not exist in the hopeless cases spoken of by Scarpa. Dr. Vetch also disapproves of letting out the aqueous humour in cases of staphyloma as art endless operation, from which no permanent effect takes place, the humour collecting again in a few hours; a sentiment which is likewise expressed by Mr. Travers. (See Vetch on the Diseases of the Eye, p. 63 ; and B. Travers , Synopsis , fyc. p. 286.) For the purpose of accomplishing the gradual diminution of the tumour, and bringing the eye into a stale in which an arti- ficial pupil may be made , Dr. Vetch has em- ployed caustic (the method commended both by Richter and Beer) and the introduction of a seton through the tumour. Beer confirms the statement of Scarpa, concerning the im- possibility of restoring the transparency of any part of the cornea affected with staphy- loma. For the relief of a partial staphylo- ma, he prefers the cautious application of the oxygenated muriate of antimony, by means of the point of a camel-hair brush, while the eyelids are held asunder. The dis- eased part of the cornea is to be smeared with it until a small white superficial slough is formed, when every particle of the caus- tic must be immediately washed out of the eye with another larger camel-hair brush, dipped in water, or milk. The application is not to be repeated until the subsequent in- flammation has quite subsided, and the slough been thrown off. Beer condemns all escha- rotic salves, because the iraction extends to pcrts which should be left uuirritated. ( Lehre ■von den Augenkr. B. 2, p. 74.) Wenzel, and numerous other writers, im- ply by staphyloma, a protrusion of a piece of the iris through a wound or ulcer of the eye. (See Iris, Prolapsus of.) R. Fr. B. Ho elder. De Staphylomale, Tu- bing# , 1748. Scarpa Suite Malatlie Degli Occhi, Ed. 5. G J. Beer's Ansicht der Sta- phylomatosen Melamorphosen des Auges , tyc. IVien. 1805. jYachtrag zur Ansicht , $-c. 1806; and Lehre von den Augenkr. B. 2 ,p. 69,8 vo. Wien. 1817. Richter, Anfangsgrunde der Wundarz n eykunst , B. 3. p. 153. fyc. Gotl. 1795. Sabatier, Mddecine Operaloire. T. 2, p. 191, Ed. 2, 1810. James Wardrop . Essays on the Morbid Anatomy of the Human Eye, Vol. 1 , p. 99, 8 vo. Edinb. 1808. £. Travers , Synopsis of the Diseases of the Eye, 8 vo. Load. 1820. J. Vetch , A Practical Treatise on the Diseases of the Eye, 8 vo. Lond. 1821. •STEATOMA. (from i) SUFPU RATION cure of scabies. Asa caustic, it is not gene- rally eligible, because it is difficult to limit its operation exactly to the parts which are intended to be destroyed. A few years ago, a proposal was made to apply this acid along the outside of the eyelid, in cases of trichia- sis, so as to produce a slough, and subsequent ulcer, the cicatrization of which draws out the inverted tursus. Nay, it is alleged that the application sometimes produces an in- stantaneous amendment of the position of the eyelid. I have seen one example, in which the experiment was tried ; but whe- ther it was owing to the acid not having been sufficiently applied, or other causes, the method did not answer so well as the usual plan of removing a part of the integuments with a cutting instrument. Diluted sulphuric acid is frequently em- ployed as an ingredient in gargles. It is also commonly exhibited with a view of check- ing passive hemorrhages, and profuse noctur- nal sweats in hectic fever. The dose is from ten to thirty drops. This acid, in the diluted form, has been tried in venereal cases. According to Mr. Pearson, when a bad state of health prohi- bits the introduction of mercury, the case has not yet put on an unequivocal appear- ance, or dyspeptic symptoms, attended with profuse perspirations, harass the patient, it is an useful remedy, capable of giving a temporary check to the progress of the dis- ease. He says, that he has often seen it arrest the progress of venereal ulcers of the tonsils, and make venereal eruptions fade and nearly disappear ; but that these bene- ficial effects were never permanent. At the same time he acknowledges that the medicine will confer actual and durable be- nefit in ulcers of the penis, groin, and throat, sometimes remaining stationary after a mer- curial course. He has likewise found this acid very efficient, when mercury acts too violently upon the mouth. (See Pearson's Obs. on the Effects of various Art hies in the Cure of Lues Venerea, p. 189 — 191, Ed. 2.) In cases of poison by sulphuric acid, the most successful treatment consists in ma- king the patient drink large quantities of water, in which calcined magnesia is sus- pended. Should this last medicine, how- ever, not be at hand, soap, blended with water, is the best substitute. While these remedies are preparing, copious draughts of some mucilaginous beverage, milk, or even of common water, should be administered without delay ; for the practitioner should ever be mindful, that so rapidly does sulphu- ric acid operate upon the texture of the parts with which it comes into contact, that all chance of saving the patient must depend upon the quickness with which the means to counteract the poison are applied. After the acid has been diluted and neutralized, local and general bleeding, emollient clys- ters, and mucilaginous drinks, constitute the best remedies. ( Orfila , Traitt des Poisons , fyc. Vol. 1. p. 434, Ed. 2.) SUPPRESSION OF URINE. See Urine , Retention of. SUPPURATION. A process, by which a peculiar fluid, termed pus, is formed in the substance, or from the surface of parts of the body. From the observations made in the article inflammation , it appears, that when this last affection is above a certain pitch, it sometimes terminates in suppura- tion. When purulent matter accumulates in the part affected, it is termed an abscess , which is distinguished into several kinds, the ccw/e, chronic, venereal, scrofulous , &c. It is observed by Professor Thomson, that the texture, in which suppuration seems to be most readily produced, by a certain de- gree of inflammation, is mucous membrane, whether this lines excretory ducts, or canals, or covers the inner surfaces of the respira- tory, or urinary organs. In a few hours, after an irritating cause has been applied to these surfaces, the physical and cbymical qualities of the fluid which they secrete in their natural state, are changed. From being a tough viscid substance, not easily miscible with water, the mucus of the nose and bronchia becomes, during an attack of inflammation, very readily miscible with water, of a yellowish white colour, and fluid consistence. If, in this state, the secretion from these membranes be examined with the microscope, it will be found to contain small globules, similar to those which are seen in the blood ; and these globules are found to increase in number in proportion to the degree and continuance of the inflam- mation. We have examples of the produc- tion of this pus, or at least of a puriform fluid, in the respiratory organs of persons affected with catarrh, and in the urinary organs of those who labour under gonor- rhoea. In the progress of these diseases, we can generally trace the changes, which take place by slow, but sensible degrees, in the nature of the secretion, from mucus to pus, and from pus back again to the state of mucus. This puriform discharge from mucous membranes, in a state of inflamma- tion, may be kept up for months without these membranes appearing to undergo auy other morbid changes than a slight degree of redness and swelling. A loss of substance, or ulceration, is found not to happen of- tener than in one case out of ten examples of suppuration from mucous membranes. ( Thomson's Lectures on Inflammation, p. 305, 306.) The same well-informed writer afterward proceeds to explain, that suppuration may be readily produced in the skin, or cutane- ous texture, by whatever excites inflamma- tion in that texture, and causes a separation of the cuticle. We have examples of this fact in blisters from cantharides, and in ve- sications of the cuticle from superficial burns. If the cuticle covering a recent blister, or burn be removed, and the cutis exposed to the irritation of stimulating sub- stances, pus will soon be discharged from the abraded surface. Suppuration can be kept up in cutaneous texture, for an indefi- nite length of time, as we see done every SXJPPURATIOX uay iu the management ot perpetual blis- ters. Ulceration is seldom observed in these cases, and consequently, in cutaneous tex- ture, loss of substance is by no means ne- cessary for the production of pus. If the cutis be divided, as in a wound, or a portion of it remov ed, as in the extirpation of tumours, and either the air, or any other external body, be permitted to remain in contact with the divided surfaces, the pro- cess of suppuration is speedily induced in the cellular texture subjacent to the skin. After the hemorrhage, which takes place from the small vessels, has ceased, an oozing of a fluid, at first resembling serum, occurs, which is gradually changed into pus. But in this case, as Dr. Thomson has correctly observed, the surface of the wound is pre- viously covered with a layer of coagulable lymph, which is penetrated with blood-ves- sels, and gradually raised into the little red eminences, termed granulations. Appearances similar, though slighter in degree, says Dr. Thomson, are observed in cutaneous suppuration, giving probability to the opinion of Sir E. Home, that in inflam- mation, a vascular surface is produced pre- viously to the formation of pus in a cellular membrane, and perhaps also in cutaneous texture. Dr. Thomson is inclined to be- lieve, however, that no new vascular sur- face is generated in the inflammation of mucous membrane. Thus, we see, that in the formation of pus in raucous membrane, cutaneous texture, and exposed cellular sub- stance, no ulceration, no breach of sub- stance occurs : but that, on the contrary, in two of these textures, the cutaneous and cellular, there is an addition made to the parts by the exudation of coagulable lymph, which becomes organized. ( Thomson , p. 305—308.) SYMPTOMS OF SUPPURATION. When matter is fully formed in a tumour, there is a remission of all the symptoms. The throbbing pain, which was before fre- quent, now goes off, and the patient com plains of a more dull, constant, heavy pain A conical eminence, or pointing , as it is termed, takes place at some particular part of the tumour, generally near its middle. In this situation, a whitish, or yellowish ap- pearance is general observable, instead of a deep red, which was previously apparent, and a fluctuation of a fluid underneath may be discovered, on a careful examination with the fingers. Sometimes, indeed, when an abscess is thickly covered with muscles and other parts, the fluctuation cannot be ea- sily distinguished, though, from other concur- ring circumstances, there can hardly be the least doubt of there being even a very con- siderable collection of matter. An oedema- tous swelling over the situation of deeply- situated abscesses is a symptom which of- ten occurs, and is well worthy the attention of every practical surgeon. The discovery of the existence of deep abscesses is a circumstance of the highest importance in practice, and one which greatly involves the practitioner's reputa- tion. In no part of the surgeon’s employ- ment is experience in former similar cases of greater use to him than in the present ; and however simple it may appear, yet no- thing, it is certain, more readily distinguishes a man of observation and extensive prac- tice, than his being able easily to detect collections of deep-seated matter. On the contrary, nothing so materially injures the character and professional credit of a sur- geon, as his having in such cases given aa inaccurate or unjust prognosis ; for, in dis- orders of this kind, the nature and event of the case are generally at last clearly demon- strated to all concerned. Together with the several local symptoms of the presence of pus, already enumerated, may be mentioned the frequent shiverings , to which patients are liable on its first for- mation. However, these rigours seldom oc- cur so as to be distinctly observed, unless the collection of matter is considerable, or situated internally in some of the viscera. In the progress of the fever, accompa- nying acute inflammation, (says Professor Thomson) rigours, or cold shiverings not un frequently take place, which recur at ir- regular intervals, and are in general follow- ed by a hot fit, and slight increase of the febrile symptoms. These rigours, or cold shiverings, in general indicate, when they occur in the progress of inflammatory dis- eases, that pus either is formed, or is about to be so. In inflammation, succeeding to injuries of the head, these rigours are often the first constitutional symptoms which give alarm to the well-informed practitioner : for they are generally, though not always' an indication that inflammation has already made a dangerous, if not fatal progress. These rigours also accompany the forma- tion of pus in the viscera contained within the cavities of the chest and belly, and are often the first symptoms which inform the practitioner, that his endeavours to procure resolution have not been successful.” (See Thomson's Lectures on Inflammation, p. 321.) Rigours, as Mr. Hunter remarked, are more common at the commencement of spontoneous inflammations, than in inflam- mations from external injury. They seldom occur in the suppurations which follow- operations. The constitutional symptoms which attend the formation of pus in the progress of chro- niesuppurations, are generally comprehend- ed under the name of hectic fever. (See Fevers.) The pain attending what Mr. Hunter termed the suppurative inflammation, is in creased at the time when the arteries are dilated, and this gives the sensation called throbbing, in which every one can count his own pulse, by merely paying attention to the inflamed part. Perhaps, this last symptom is one of the best characteristics of this species of inflammation. When the in- flammation is moving from the adhesive state to the suppurative, the pain is conside- rably increased ; but when suppuration has sUPPUKATICtt *6-1 taken place, the pain m some degree sub- sides. (Hunter.) The redness that took place in the adhe- sive stage is now increased, and is of a pale scarlet colour. The part which was firm, hard, and swelled, in the previous stage of the inflammation, now becomes still more swelled, in consequence of the greater dila- tation of the vessels, and the greater quan- tity of coagulating lymph thrown out. (Hunter.) THEORY OF SUPPURATION. The dissolution of the living solids of an animat bod) 7 into pus, and the power of this fluid to continue the dissolution, are opinions which are no longer entertained . by any well-informed surgeons of the present day ; and the use of such phrases as a pus corrodes,” :l it is acrid,” &c c. expressions vrbich imply an erroneous way of thinking, is very pro- perly almost entirely discontinued in the language of every sinsible medical man. If these notions were true, no sore which dis- charges matter, could be exempted from a continual dissolution. Such ideas probably arose from the circumstance of an abscess being a hollow cavity in the solids, and from the supposition, that the whole of the original substance of that cavity was now the matter, which was found in it. This was a very natural way of accounting for the formation of pus by one entirely igno- rant of the moving juices, the powers of the arteries, and what takes place in an abscess after it is opened. The knowledge of these three subjects, abstracted from the know- ledge of the abscess before its being opened, should have led surgeons to account for the formation of pus from the blood by the pow- ers of the arteries alone. According to the above erroneous principle, abscesses would continue to increase after being opened, as fast as before. Upon the principle of the solids being dissolved into pus, was founded the practice of bringing ail indurated parts to suppuration if possible, and not making an early opening. This was done for the purpose of giving time for the solids to melt down into pus ; but it was apparently for- gotten, tiiat abscesses formed matter after they were opened, and therefore the parts stood the same chance of dissolution into pus as before. Blinded with the idea that ?he solids entered into the composition of pus, the partisans of this doctrine could never see pus flowing from any internal canal, as from the urethra, in cases of gonorrhoea, without supposing the existence of an ulcer . the passage. Such sentiments might be forgiven before it was known that those sur- faces could, and generally did, form pu3 without a breach of the solids ; but the con- tinuance of this way of thinking now is not mere ignorance, but stupidity. The forma- tion of pints of matter in the cavities of the chest and abdomen, without any breach in the solids, could not have been overlooked by the most zealous advocates for the doc- trine of dissolution. (Hunter.) The moderns have been still more ridicu- lous; for knowing that it was denied, that the solids were ever dissolved into pus, acd that there was not n single proof of it, they have been busy in producing what to them seemed a proof. They have been putting dead animal matter into abscesses, and find- ing that it was either wholly or in part dis- solved, they therefore attributed the loss to its being formed into pus. This, howe- ver, was putting living and dead animal matter upon the same footing, which is a contradiction in itself; for if the result of this experiment were really what they sup- posed it to be, the idea of living parts being dissolved into pus must be abandoned, be» cause living and dead animal matter can never be considered in the same light- (Hunter.) It might have been remarked, that even extraneous animal matter w ould lie in ab- scesses for a considerable time without be- ing dissolved, and that in abscesses arising either from violence, or from a species of erysipelatous inflammation, there were often sloughs of the eeiluiar membrane, which sloughs would come away like wet tow, and therefore were not dissolved into pus. (Hun- ter.) It might also have been noticed, that in abscesses in tendinous parts, as about the ankle, a tendon often mortified and sloughed away, and that the sores would not heal til! such sloughs were detached ; but though this separation was sometimes not completed be- fore the expiration of months, yet the sloughs at last were thrown off, and consequently could not be converted into pus. Pieces of dead bone often lie soaking in matter for many months, without being changed into pus; and although bones, so circumstanced, may lose a considerable deal of their substance, a loss which some might impute to the dis- solution of the bone into pus, yet that waste can be accounted for and proved on the principle of absorption. The loss is always upon that surface, upon which the continuity is broken off, and it is a part of the process by which exfoliation of a dead piece of bone is accomplished. The forma- tion of pus has been attributed to a kind of fermentation, in which both the solids and fluids were concerned. This doctrine is easily retuted by stating what happens in internal canals, which naturally secrete mu- cus, but frequently form pus, without any loss of substance, or any previous ferment- ing process. Were we to suppose a fer- mentation of the solids and fluids, the imme- diate cause of the production of pus, whence could the solids come, which enter into the composition of discharges from the urethra ? for the whole penis could not afford matter enough to form the pus, which is discharged in a common gonorrhoea. How also could the fermentation of the solids ever cease ? for there is the same surface secreting its mucus, whenever the formation of pus is discontinued. It may be asked likeivise, by w hat power the first particle of pus in an abscess, or on a sore, is formed, before there is any particle existing, which is capable of dissolving the solids? An abscess may be SUPPURATION. 433 * stationary for months, and at last be absorb- ed ; what becomes of the fermentation all the while the collection of matter continues stationary ? Extravasated blood has been supposed to be capable of being converted into pus. We find, however, that blood, when exiravasa- ted, either from violence, or a rupture of a vessel, as in aneurism, neverof itself becomes pus ; nor was pus ever formed in these cases, without being preceded by inflammation. Both the blood and matter are also found together in the same cavity, under such cir- cumstances. If the blood had coagulated, which it seldom does in cases of violence, it would be found still coagulated ; and if it bad not coagulated, the pus would be bloody. (Hunter.) The modern theory of suppuration is, that tbe matter is separated from the bjood by the secreting power of the vessels of the inflamed part, which acquire a new mode of action. That pus is formed in the-vessels from which it exudes, by an action of these ves- sels analogous to secretion, was, so far as I know, (says Professor Thomson) first dis- tinctly suggested by Dr Simpson of St An- drew’s, in his *• Dissertationes de Re Medico,,’ published in tbe year 1722. An opinion similar to that of Dr. Simpson’s suggested itself, about the year 1756, to De Haen, from the consideration of what takes place in some cases of phthisis pulmonalis. This author observes, that pus was often expecto- rated, for a great length of time, by patients affected with phthisis, in whom, after death, no mark of ulceration could be perceived, not even the place in which the pus had been formed. The hypothesis of pus being a secretion was afterward more fully con- sidered by Dr. Morgan of Philadelphia, in his inaugural thesis printed at Edinburgh in 1763, entitled “ Puopoioses, sive Tentamen Medicum de Puris Confectione.” The belief that pus is a secretion, or formed at least by an action of the vessels analogous to secre- tion, was adopted by Mr. Hunter. Indeed, the merit of the original suggestion of this hypothesis has been ascribed to him, though improperly. Bruggraan, professor of botany at Leyden, has maintained the same doc- trine in an excellent thesis 11 De Puogenia ,” published in 1785; and it is that which is now very gen rally taught ail over Europe. (See Thomson’s Lectures on Inflammation, p. 316, 317.) With respect to suppuration from exposed surfaces, however, it is more proper to say, that the vessels secrete a fluid, which becomes pus; for Sir Everard Home has proved, that this fluid has not the puru- lent appearance, when first secreted, but acquires it while it remains on the inflamed surface, and does not acquire it the less readily, when removed from that surface in a colourless state, provided its proper tem- perature be preserved, and it be kept ex- posed to the air, which promotes the change. The opinion that suppuration is a process analogous to glandular secretion, was at first hastily rejected by many who were Vox,. II 55 swayed by tbe fact, that no pus is ever found blended with the blood in the circulating system. By this mode of reasoning, howe ver, such thinkers must be led to deny the universally received and undoubted doctrine, that the bile is a secretion ; and yet it is well known, that nothing like this fluid can be detected in an analysis of the blood, and, in- deed, a very small quantity would be suffi- cient to tinge the whole mass of circulating blood with a yellow 7 colour, the same as we see in cases of jaundice- No one would wish to defend the idea of there being either pus, or bile, actually in the circula- tion ; but only the matter, or modifications of the matter, w hich, by tbe combinations, or whatever changes we may choose to term them, taking place in the secreting vessels, and by their operations are com verfed into one of the particular fluids in question. Violence done to parts is one of the great causes of suppuration ; but simply, violence does not always occasion it. The violence must be followed by a prevention of a cure in a more simple way, viz. by a restoration of the structure, so as to carry on the animal functions of the part. The parts must be kept long enough in that state into which they were put by the violence. Or what is somewhat similar to this, the violence must be attended with death in a part, as, in many bruises, all mortifications and all sloughs, in consequence of the application of caustic, which, when the dead pnrls separate, leave internal surfaces exposed. (Hunter.) As every injury or effect of outward vio* lence, under the above circumstances, is more or less exposed to the surrounding air, the application of air to internal surfaces has been assigned as a cause of suppuration ; but certainly the air has not the least effect on parts, circumstanced as above, for a stimulus would arise from a wound, were it even contained in a vacuum. In circumscribed abscesses, the air cannot possibly get to the parts, so as to have any share in making them suppurate In cases of emphysema, when the air is dif- fused over tbe whole body, no suppuration is tbe consequence, unless an exposure or imperfection of some internal surface should be made, for the purpose of allowing the air to escape. A stronger proof, that it is not tbe admission of air, which makes parts in- flame, is, that the cells in the soft parts of birds, and many of the cells and canals of their bones, communicating with the lungs, and always containing air, never inflame but if these cells are exposed in an unnatural way, then the stimulus of imperfection is given, these cavities then inflame, and their surfaces either form adhesions together, or produce pus. (Hunter.) When the interior of an abscess is exa- mined, the cavity which contained the mat- ter is observed to be lined w ith a smooth, raeinbranous-looking substance, which is of a whitish ash-colour, and has a strong re- semblance to coagulating lymph. This membrane-like substance has been termed 43'4 SUPPUKATlOps the sac or cyst of the abscess. This sac or cyst seems in general to adhere by a vascu- lar union to the surrounding cellular mem- brane, which is itself likewise denser in tex- ture, and more vascular than in the natural state, {Thomson' s Lectures , p. 310.) its cells being closed by coagulating lytnph, effused in consequence of that species of inflamma- tion which Mr. Hunter termed the adhesive. Thus by the formation of a cyst, and the etfusion of coagulating lymph in the cellular substance around the abscess, the collection of matter is bounded, and cannot become diffused, as it otherwise would do, in the communicating cavities of the cellular mem- brane, like the water in oedema. Something like this diffusion of pus seems to occur in erysipelas phlegmonoides. “ But in this case, (says Professor Thomson) the vitality of greater or less portions of the cellular substance is destroyed, the deadened portions are converted into dirty, whitish, ash-coloured sloughs, and it becomes ex- tremely difficult to say, whether any part of the pus contained in the deadened cellular membrane has been formed in the cells, in which itis contained, or has been absorbed into these cells, after being separated from the parietes of the cavities containing the sloughs themselves.” ( Lectures , p. 310.) There can be no doubt, that after an ab- scess has received a membranous lining or cyst, the secretion of pus is continued from the surface of the latter part entirely, as well as whatever degree of absorption of the same fluid happens to be going on. In fact, the cysts must be both secreting and absorb- ing surfaces. The circumstances which leave no doubt of this point, are the frequent, sudden, or gradual removal of very large manifest collections of matter ; the continu- al changes occurring in the quantity and con- sistence of the pus ; and the speedy filling of the cavity with purulent matter again after the first contents of the abscess have been discharged. Another thing which is yet a subject of controversy is, whether suppuration ever happens unpreceded by inflammation ? Pro- fessor Thomson, of Edinburgh, believes that the affirmative opinion on this point was first suggested by De Haen of Vienna ; but lie thinks that much of the difference of sen- timent in this matter has proceeded from the vague “ notions entertained with regard to the symptoms which necessarily charac- terize the state of inflammation, and also with regard to the properties by which pus is to be distinguished from other animal fluids. Accordingly, in almost ail the exam- ples which De Haen has adduced to prove the formation of pus, without the previous existence of inflammation, he has himself occasion to remark the exudation of coagu- lating lymph, and the existence of preterna- tural adhesions; phenomena which we know are produced by that state, which Mr. Hun- ter denominated adhesive inflammation.” But De Haen uses the term inflammation to express that state, which we deuorni- eatc ulceration, or ulcerative absorption ; for in speaking of the cases of suppuration, which he has adduced, he observes, that “ in many of them no previous loss, or con- sumption of substance could be perceived.” An observation similar to this was made about the same time, or perhaps a little earlier, by Dr. William Hunter, and an account given of it in the second volume of the London Medical Observations and Inquiries. Mr. Hunter, though he endeavours to establish it as an invariable fact, that no suppuration takes place, which is not pre- ceded by inflammation, is of opinion, that collections of what he terms extraneous matter, something like pus, may form in various parts of the body, without the pre- vious existence of inflammation in the parts in which it is formed ’; and accordingly you will find, at page 300 of his Treatise on In- flammation, a chapter entitled, ‘ Of Collec- tions of Matter without Inflammation.’ ” Professor Thomson doubts, however, “ whether these collections of matter, said to be formed without inflammation, would not have been more properly denominated scrotulous abscesses, or chronic suppurations. I am disposed to believe (says he,) that, in whatever texture or organ of the body scrofula manifests itself, there inflammation will be found to exist. The phenomena, it is true, of inflammation, both local and con- stitutional, are modified by the existence of the scrofulous diathesis ; but they are, I be- lieve, always present in such a degree as to justify us in giving to them the name of in- flammation* and in classing most, if not all, local scrofulous affections, among inflamma- tory diseases. When the indolent swellings, of which Mr. Hunter speaks, occur near to the surface of the body, that part feels warmer than usual, as may be felt in white swellings of the joints. The swelling also is either preceded or accompanied with some degree of pain, though, when the afl'ection is internal, the patient may not always be very accurate with regard to the precise seat of this pain. .When cut into, the parts also affected with scrofulous swel- lings are always found more vascular than usual ; in short, all the symptoms occur by which the state of inflammation is charac- terized.” (See Thomson's Lectures on In- flammation, p. 313, 314.) In another place, this author admits that the matter, which is formed in chronic suppurations, does not always accurately resemble that which is formed in acute abscesses; but yet he con- tends that it is so analogous both in its physical and chymical.characters, as well as in the circumstances in which it is produced, that he can see no reason why it should not be called pus, or a puriforra fluid, (fl. 315.) q.UAUTIES OF PUS. True pus has certain properties, which, when taken singly, may belong to other se- cretions, but which, conjointly, form the peculiar character of this fluid, viz. globules swimming in a fluid, which is coagulabte SUPPURATION. 435 by a solution of the muriate of ammonia, which no other animal secretion is, and at the same time a consequence of inflamma- tion. The colour and the consistence of pus are the two qualities, which first attract the notice of every, the most superficial obser- ver. The colour arises from the largest portion of this fluid being composed of very : mall round bodies, very much like the globules of cream. The fluid in which the globules of pus swim, might at first be supposed to be the serum of the blood, for it coagulates with heat like the latter fluid. Pus is also probably mixed with a small quantity of coagulating iytnph ; as it partly coagulates after it is secreted. However, the fluid part of pus is found to have pro- perties which serum has not. There being a similarity between pus and milk, experi- ments have been made to ascertain whether the fluid of pus could be coagulated with the gastric juice of animals: but no coagu- lation could be effected in this manner ; a solution of muriate of ammonia made the fluid part of pus coagulate ; but not any other secretion or natural fluid ; and hence it was concluded, that whenever globules were found swimming in a fluid, coagulable by muriate of ammonia, the matter was to be considered as pus. (Hunter.) The proportion which the white globules bear to the other parts of pus, depends on the health of the parts producing the dis- charge. When the globules are very abun- dant, the matter i3 thicker and whiter, and is called healthy pus ; the meaning of which is, that the solids which produced it are in good health; for these appearances in the matter are no more than the result of certain salutary processes going on in the solids, the effect of which processes is to produce the disposition,' on wfaieh both suppuration and granulation depend (Hunter.) Pus is specifically heavier than water, and is probably about as heavy as blood. . Besides the above properties, pus has a sweetish mawkish taste, very diflereut from that of most other secretions, and the same taste takes {dace, whether it is pus from a sore, or an irritated inflamed surface. Pus has a smell in some degree peculiar to itself ; but this differs in different cases. Some diseases, it is said, may be known by the smell, as for instance, a gonorrhoea. Pus sinks in water ; mucus floats. Pus communicates to water an uniformly trou- bled white colour; mucus gives the appear- ance of stringy portions floating in it. Mucus is said to be more readily dissolved by sulphuric acid than pus is. It has also been asserted, that if water be added to such solutions, the pus is precipitated to the bottom of the vessel ; while the mucus, instead of being completely precipitated, forms swimming flakes. A solution of caus- tic alkali dissolves both pus and mucus ; but when water is added, the pus is said to become separated, but not the mucus. Though solutions in chymical menstrua and precipitations, have been thought a test of the distinction between these two fluids, yet the method has been thought absurd and unphilosophical. It has been conceived, that all animal substances what- ever, when in solution, either in acids or alkalies, would be in the same state, and therefore, that the precipitation would be the same in all. Calcareous earth, when dissolved in muriatic acid, is in that acid in the same state, whether it has'been dissolved from chalk, limestone, marble, or calcareous spar, and precipitations from all are the same. Hence, experiments were made on organic animal matter, such as muscles, tendon, car- tilage, liver, and brain ; and on inorganic, such as pus and the white of an egg. Ail these substances were dissolved in sulphuric acid, and precipitated with potassa. Each precipitation was examined with such mag- nifiers, as plainly showed the forms of the precipitates, all which appeared to be flaky substances. The precipitate by ammonia had exactly the same appearance. The same appearances were seen, when the above kinds of animal matter were dissolved by caustic potassa, and precipitated with the muriatic acid. A flaky substance, void of any regular form, composed each precipi- tate. (Hunter.) For additional observations on the tests of pus, and an account of those suggested by Dr. Young and Grasmeyer, see the First Lines of the Practice of Surgery ) Vol. l,p. 32, Ed. 4. Pus does not irritate the particular surface which secretes it, though it may be very ir- ritating to any other. Hence, no suppura- ting surface of any specific kind, can be kept up by its own matter; if this had not been the case, no sore of a specific quality, or producing matter of an irritating kind, could ever have been healed. This is simi- lar to every other secretion of stimulating fluids, as the bile, tears, &c. which fluids do not stimulate their own glands, or ducts, but are capable of stimulating any other part of the body. (Hunter.) Whenever a real disease attacks, either the suppurating surface, or the constitution, the production of true pus ceases, anti the fluid becomes changed in some measure, in proportion to these morbid alterations. In general it becomes thinner and more transparent, and it partakes more of the na- ture of the blood, as is the case in most othersecretions under similar circumstances. Sanies is the term usually applied by surge- ons to pus, in this degenerated state. This unhealthy sort of matter has more of the se- rum, and frequently more of the coagula- ting lymph in it, and less of the combination which renders it coagulable by a solution of muriate of ammonia. It has also a greater proportion of the extraneous parts of the blood, which are soluble in water, such as salts ; and it has a greater tendency, than true pus, to become putrid. Such unheal- thy matter may even be irritating to the surface which produces it. The discharge, when of an irritating sort, is more stimulating to the adjoining parts with which it comes in contact, than to its SUPPURATION. '136 own secreting surface. In this manner it cns silver probes, and preparations of lead, frequently produces excoriation of the skin This effect is imputed by Dr. Crawford to smd ulceration. Thus the tears excoriate the sulphurated hydrogen gas, generated in the skin of the cheek, in consequence of the the matter. (Phil. Trans, vol. 80, Fear 1790 3 quantity of salts which they contain. From p. 385.) Further interesting observations this effect, matter has been called corrosive, on the nature of pus may be found in an a quality which it has not ; the only proper- Essay on the Differences between Pus and ty which it possesses being that of irritating Mucus, by Dr. Darwin, junior ; also in Dr. parts which it touches, so as to cause their G. Pearson’s Paper in Philos. Trans. 1811. absorption. (Hunter.) When the vessels thus lose the power of use of pus. producing good pus, they also lose more or less the power of forming granulations. By some it is supposed to carry off hu- This may depend on some deviation from mours from the constitution. Suppuration the due structure and action, which such is sometimes regarded as a constitutional vessels should possess, in order to be qua- disease, changed into a local one, which con- lifted for the performance of these two ope- stitutional malady is discharged, or thrown rations. out of the body, either in the form of pus. Pus, from several circumstances, would or together with this fluid. Critical abscess- appear in general to have a greater tenderly es have been thought to be cases of this cy to putrefaction than the natural juices sort. Suppuration has also been imagined have; but, perhaps, this is not the case with to carry off local complaints from other pure pus, which, when first discharged from parts of the body, on the old principle of an abscess, is commonly perfectly sweet, derivation or revulsion. For this reason, There are, however, some exceptions to this, sores or issues are made in sound parts be- but these depend on circumstances entirely fore allowing other sores to be dried up. foreign to the nature of pus itself. Thus, if Suppuration is sometimes excited u T ith a the abscess had any communication with the view of making parts, such as indurated air, while the matter was confined in it ; or swellings, dissolve into pus ; but I have en- if the collection has been so near the colon deavoured to show, that no dissolution of or rectum as to have been infected by the the solids is concerned in the production of feces, then we cannot wonder that the mat pus. ) ter should become putrid. When blood is A secretion of pus is looked upon as a ge* blended with pus; when sloughs are mixed neral prevention of many, or of all the cau- with it ; when the parts forming the seat of ses of disease. Hence, issues are made to the abscess are in a gangrenous state from an keep off both universal as well as local dis- erysipelatous affection ; the matter has a eases. However, the use of pus is perhaps greater tendency to putrify than the pure unknown ; for it is formed most perfectly pus discharged from sound abscesses or heal- from healthy sores, and in healthy constru- ing sores. Pure matter, though easily ren- tions ; and large discharges from parts not dered susceptible of change, by extraneous very essential to life, produce very little additions, is in its own nature tolerably uni- change in the constitution, and as little upon form and immutable. It appears so un- being healed up, whatever some may sup- changeable, that we find it retained in an pose to the contrary. (Hunter.) abscess for weeks, without having undergone This is certainly the case with many old any alteration. These qualities, however, ulcers, the suppuration from which seems only belong to perfect pus. If a healthy to have little or no effect in impairing the sore inflames, the matter now produced from health. Nor is there any real reason to be it, though unmixed with extravasated blood, afraid of healing such ulcers, when possible, or dead solids, becomes much sooner putrid, lest a worse disease should follow from the and much more irritating, than the discharge stoppage of a discharge to which the system formed before this alteration of the ulcer, is supposed to be so habituated that the (Hunter.) continuance of it must be essential to In the preceding paragraph it is stated, health that matter remains very often unchanged Every one know s, that when there is no in abscesses for weeks. This expression of interference of art, that is. when the surface Hunter’s is not strictly correct ; for it is w ell of a sore is left uncovered, the thin part of known, that the surfaces of the cavities of the matter evaporates, and the thick part abscesses are always absorbing, as well as dries and forms a scab. Nature, therefore, secreting ones ; consequently, there must seems to have designed that one use of pus be a continual mutation going on in the con- should be to make a cover, or protection tained matter. for ulcerated surfaces. But I cannot agree When there are diseased bones, or other w r ith what has been asserted, (Hunter) that extraneous bodies, exciting irritation, some- the natural healing of a sore under a scab times even in so great a degree as to make\ takes place more quickly than when surgi- the vessels bleed, and often wounding the cal dressings are employed, vessels of the part, the matter is always On ulcers, as would appear from modem found to be very offensive. This state of microscopical observations, u the coagula- the discharge is one mark of a diseased ted pus is rendered tubular by the extrica- fcone. tion of its carbonic acid gas, and that these The discharge of an unhealthy sore black- tubes, or canals, are immediately filled with SUPPURATION red blood, and thus connected with the cir- culation.” If this point be established, Sir Everard Home conceives that there will then be little difficulty in making out the succeeding changes, by means of which the coagulated pus afterward becomes or- ganized. (On the conversion of Pus into Granulations or new Flesh , in Phil. Trans. Vol. 109, p. 109, Lond. 1819) These state- ments are curious, and ought to have been noticed in the article Granulations, to which they more immediately relate. Among the secondary uses of suppura- tion, maybe mentioned, opening a commu- nication between a disease and the external surface of the body ; forming a passage for the exit of extraneous bodies, be. TREATMENT WHEN SUPPURATION MUST TAKE PLACE. In cases of inflammation, arising from accident, but so circumstanced, that w r e know suppuration cannot be prevented, the indication is to moderate the inflammation, which, if the powers are great, and the in- jury done considerable, will probably be very violent. If the constitution should also be much affected, certain general means are proper, such as bleeding, purging, and nau- seating medicines. While the constitution continues to be disturbed, suppuration can- not take place in the most favourable man- ner. In these cases, also, such medicines as produce a gentle perspiration greatly re- lieve the patient, for instance, the pulv. ipecac, comp.; antimonials; aq. ammon. acet.; saline draughts, fee. Opiates may produce a temporary diminution of action; but it is not always the consequence of this medicine, as there are constitutions which it renders more irritable, and of course where it aggravates the inflammatory ac- tion. The applications to inflammations, which are to suppurate and form an abscess, com- monly used are poultices and fomentations. These, however, appear to be applied with- out much critical exactness or discrimina- tion ; for they are applied before suppura- tion has taken place, and when this event is not desired ; and they are also applied after suppuration has taken place. With respect to suppuration itself, abstracted from all other considerations, the indication cannot be the same in every state . but if poultices and fomentations are found to be of real service in the two stages of the dis ease, there must be something common to both, for which they are of service, inde- pendently of simple suppuration. Poultices are useful when the inflammation attacks therskin, either in the first instance or after an abscess has approached so near the skin that this becomes secondarily affected. This benefit appears to arise from the skin being kept soft and moist. Such is the use of a poultice in inflammation, either before or after suppuration, until the abscess is open- ed. But, when poultices and fomentations are applied to inflamed parts, in which we wish to avoid suppuration, reason and prin- ciple will not justify the practice, though such applications may be proclaimed by experience to be very proper. (Hunter.) TREATMENT' AFTER SUPPURATION HAS TAKEI7 PLACE. When suppuration cannot be stopped, or resolved it is in general to be promoted. How far suppuration can be usefully pro- moted by medicines or applications, is questionable; but attempts are generally made, and, for Ibis purpose, suppurating cataplasms and plasters, composed of the warm gums, seed's, kc. were formerly much recommended. Mr. Hunter doubted, whe- ther such applications had any considerable effect in the way intended ; for, if they were put on a sore, they would hardly increase the discharge from it, and perhaps even di- minish it. However, in many cases in which the parts are indolent, and hardly admit of true inflammation, in consequence of which a perfect suppuration cannot take place, stimulating the skin brings on a more salu- tary, and of course a quicker inflammation. Thus the antimonial ointment, and blister - ing the skin, over chronic swellings and abscesses, are sometimes indicated. These applications have been found, how- ever, to bring the matter more quickly to the skin, even in the most rapid suppura- tions. This effect has been mistaken fox 3 an increased formation of pus ; but this consequence can only follow in cases in whi> h the inner surface of the abscess is within the influence of the skin. The ac- celerated progress of the matter to the sur- face of the body arises from another cause, viz. the promotion of ulceration in the parts, between the collection of matter and the cu- ticle. Emollient poultices are commonly ap- plied to inflamed parts, when suppuration is known to have taken place. These can have no effect upon suppuration, except that of lessening the inflammation, or ra- ther making the skin. more easy. The in- flammation must have reached the skin before poultices can have much effect, for they can only affect that part. The ease of, the patient, however, should be considered, and We find that fomentations and poultices are often beneficial in this way. By keep- ing the cuticle moist and warm, the sensi- tive operations of the nerves of the parts are soothed. On the contrary, if the infla- med skin is allowed to dry, the inflamma- tion is increased, and as suppuration is pro- bably not checked by the above treatment, it ought to be put in practice. As warmth excites action, the fomentation should be as warm as the patient can bear without in- convenience. (Hunter.) “ The local treatment in phlegmonous abscesses (as professor Thomson observes) is still more simple than that by which we endeavour to procure resolution. It con- sists almost solely in the application of a moderate degree of warmth and moisture Suppuration. 4.3s to the inflamed pari, either by means of fomentations or poulticed. The manner in which these means act in promoting sup- puration is unknown, independently of their temperature, it seems very doubtful whether fomentations and poultices have any power of promoting suppuration in the parts to which they are applied. They keep the cuticle moist and warm, they promote perspiration, they sooth and allay pain in many inflammations, and these are probably the only immediate effects which they pro- duce. The rest is the work of nature. In suppurations, attended by very sevefe pain, the use of w arm fomentations is often found to atford singular relief, not only by their effect in easing pain, but also by their seem- ing to shorten the duration of the suppura- tive stage. In the cases of suppuration, in which they give relief, they should be re- peated every four or six diours. The most common way of employing them is by wringing linen, or woollen cloths, out of warm water, and applying these to the in- flamed part, of as high a temperature as the feelings of the patient can bear. Decoc- tions of herbs were formerly much employ- ed in the way of embrocation, and were then, and are still, by many practitioners, supposed to possess peculiar virtues in pro- moting suppuration. Whether embroca- tions with the narcotic herbs might not in some cases be beneficial, by producing a sedative effect in allaying pain, I arn una- ble to say, though 1 am inclined to believe that even they act chiefly by their warmth and moisture. In cases where you find it necessary to use an embrocation with herbs, the flowers of chamomile may in general be substituted in place of the leaves or flowers of almost every other plant. These flow- ers readily imbibe and retain moisture. They are, when moist, of a soft consistence, and can be easily moulded to the figure of the parts to which they are applied.” (Thomson’s Lectures , p. 333.) Oatmeal, crumb of bread, and especially linseed meal, are the ingredients mostly preferred in this country for emollient poultices. When bread is used, it is generally boded in milk. The observations, however, Which have been offered on poultices in another place, are here equally applicable. (See Inflammation.) OF THE TIME WHEN ABSCESSES SHOULD BE OPENED. As abscesses, wherever formed, must in- crease that part of their cavity which is next to the skin, more quickly than the bottom, they must become, in some degree, tapering towards the latter part, with their greatest breadth immediately under the skin. This shape of an abscess, when allow- ed to take place is favourable to its healing, for it puts the bottom, which is the scat of the disease, more upon a footing with the mouth of the abscess than it otherwise could be. As the bottom, or part where the ab- scess began, is more or less in a diseased state ; and as the parts between the seat of the abscess and the external surface are sound parts, having only allowed a passage for the pus, they, of course, have a stronger disposition to heal than-the bottom has. To keep the mouth of an abscess from healing before its bottom, the collection of matter should be allowed to break of itself; for although abscesses in general only open by a small orifice, more especially when sound, yet, in such cases, the skin over the general cavily of the matter is so thinned, thatit has very little tendency to heal, and often ulcerates and makes a free opening. If the latter event should not spontaneously occur, it may now be more easily obtained by the interference of the surgeon. Abscesses w hich are the most disposed to heal favourably, are the quickest in their progress to the skin, and the matter comes to the surface almost at a point ; the swell- ing is not so conical as in other cases, and when it bursts the orifice is exceedingly small. On the other hand, when there is an indolence in the progress of the abscess, the collection spreads more, or distends the surrounding parts in a greater degree, in consequence of their not being so finely united by inflammation in the one as they are in the other instance ; nor will ulcera- tion so readily take the lead, and the matter will come to the skin by a broad surface, so as to thin a large portion of the cutis. (Hunter.) It may be set down as a general axiom, that alf phlegmonous abscesses should be allowed to break, and not be opened by the surgeon. When punctured unnecessarily, or prematurely, they never heal so favoura- bly as when left to themselves. Particular cases, however, should be opened as soon as the existence of matter is ascertained. Abscesses should only be allowed to burst of themselves, when the confinement of the matter can do no mis chief. Abscesses in tbe abdomen or tho- rax, under the cranium, near the eye, or in joints, should be mostly opened very soon. When suppuration takes place beneath liga- mentous expansions, or aponeuroses, which invariably retard the progress of the matter to the surface of the body, an early opening should be made. It this be not done, the matter spreads to a great extent, separating such ligamentous expansions from the mus- cles, and the muscles from each other, and, as the pus cannot get to the surface of the body; the length of the disorder is of course increased. When matter is so situated as to be liable to insinuate itself into the chest or abdomen, or into the capsular ligaments of the joints, it is highly proper to prevent this extension of mischief, by making a timely opening into the abscess. u Those abscesses ought to be opened early, (says Professor Thomson) that are situated in parts through which the matter is liable to become widely diffused. This is particularly the case with abscesses that are situated on the forepart of the neck, or in the cavity of the axilla, or by the side of SUPPURATION. 433 iii e rectum. When matter is formed In the cavity of the axilla, if it does not speedily obtain an external outlet, it is very liable to pass up towards the clavicle in the course of the axillary plexus of nerves and vessels, or forwards under the pectoral muscle. I have repeatedly seen axillary abscess take both of these directions at the same time, forming one of the most painful and diffi- cult cases to treat which occurs in the ma- nagement of abscesses.” Dr. Thomson also considers an early opening proper and ne- cessary, where the matter is lodged, as in some cases of whitloe, in the sheaths of the tendons; where matter is formed under the periosteum ; where it collects under fas- ciae, or in the vicinity of large arteries, joints, or the greater cavities of the body: also when the abscess is deep-seated. (See Thomson’s Lectures on Inflammation , p. 336 — 338 .) With respect to making an early opening into abscesses, situated near large arteries, I am not aware, that any danger of the ar- tery ulcerating in consequence of the near- ness of the pus, really exists. Therefore, some doubts may reasonably be entertained of Professor Thomson’s advice in this par- ticular case, as the general rule of opening abscesses nearHarge blood-vessels, in an early stage of the disease, would be objec- tionable on the ground of the practice ex- posing the vessels themselves to injury. Indeed, this well-informed writer distinctly mentions, in considering the subject in question, that the arteries are not very susceptible of ulcerating absorption. (P. 337 .) OF THE PLACE WHERE THE OPENING SHOULD BE MADE. If a free opening is not required, or ma- king one is not practicable, it is at least pro- per to make whatever opening can be made in a depending situation. By this means the matter will more readily escape, and all pressure arising from the confinement or lodgment of pus, will be prevented. Avery small degree of pressure on that side of the abscess which is next to the skin, may pro- duce ulceration there ; and although such pressure might not, in many cases, be so great as to produce ulceration at the bottom of the abscess ; yet it might be sufficiently great to prevent granulations from forming on that side, and thereby retard the cure, as no union can take place, but by means of granulations. The pressure is always most, and retards the formation of granula- tions in the greatest degree, at the most de- pending part of the abscess. Hence, if no opening be made in this situation, tbw upper part of the abscess readily heals to a small point, which becomes a fistula. When circumstances forbid making an opening at the most depending part of an abscess, perhaps nothing more can be done, than to evacuate the matter as often as ne- cessary, and gently^to compress fixe sides of the abscess together, when the situation of the case admits of the practice. But abscesses are not always to be open- ed at the most depending part. The distance between the matter and- the skin at this part is the common reason against the method. If an abscess is rather deeply situated, and points in a place which is higher than where the collection lies, it is proper to make the opening where the conical eminence, or as it is terme.d, the pointing, appears. Thus, if an abscess should form in the centre of the breast, and point at the uppermost part, which is often the case, jt would be impro- per to cut through the lower half of the mamma, in order to make a passage for the matter in that direction. If an abscess should form on the upper part of the foot, it would be wrong to make an opening through the sole of the foot to get at the most depending part of the abscess ; (or, besides cutting such a depth of sound parts, a great many useful ones would be destroyed. When the abscess does not point in a de- pending situation, as in the instances just cited, since the place where the matter threatens to open a passage is likely to be the future opening, and this situation is dis- advantageous to the healing of the deep part of the abscess, it is generally best to let tbe collection of matter first burst of itself, and then dilate the opening as freely as necessary. By allowing abscesses to burst spontaneously, the opening is not so apt to heal as if made by art, and therefore, is better in such situations. (Hunter.) In most cases, it is more advantageous erven to cut through a certain thickness of parts, for the sake of obtaining a depending opening, than to make an opening, where the pointing appears, that is, where the parts are thinnest, and the matter nearest the sur- face. This remark is highly worthy of re- membrance, when there is no doubt of the existence of matter at the depending place, and when the parts to be divided are not im- portant ones. Collections of matter be- neath the fasciae of the fore-arm and thigh particularly demand attention to this direc tion, as they commonly point where thgsc ligamentous expansions are thinnest, not where the matter can most readily escape. Abscesses in the sheath of the rectus ab- dominis should also be opened in a low situ- ation. DIFFERENT METHODS OF OPENING AB 1 SCESSES. All abscesses will naturally burst of them- selves, unless the matter be absorbed, and, in general, they ought to be allowed to take this course. There are, however, as I have already explained, particular circum stances which require an early opening ; but, when the skin over the abscess is very thin, it is not (ff so much consequence, whether the case be permitted to burst of itself, or it be opened by the surgeon. When abscesses are large, it is generally SUPPURATION, m necessary to open them by art, whether they have hurst of themselves or not; for, the natural opening will seldom be sufficient for the completion of a cure ; and, although it may be sufficient for the free discharge of the matter, yet these abscesses will heal much more readily when a free opening is made ; for, the thin skin over the cavity granulates but indifferently, and therefore unites but slowly with the parts underneath. (Hunter.) Abscesses may be opened either by an incision or by making an eschar with caus- tic. To the latter pjan, however, many urge strong objections : the use of caustic is not usually attended with any advantage which may not be obtained by a simple incision ; upon a tender inflamed part it gives much more pain ; it is more slow in its effects ; and the surgeon can never direct the ope- ration of the caustic so accurately as to de- stroy exactly the parts which he wishes, and no more. If the eschar be not made deep- ly enough, the lancet must, after all, be used Caustic also leaves, after its applica- tion, a disagreeable scar, a consideration of some importance in opening abscesses about the female neck or face. To these nume- rous objections we have to add, that the eschar is, very frequently, ten or twelve te- dious days in becoming detached. When there is a redundance of skin, or when there is a good deal of it thinned, however, an opening made with caustic will answ r er, perhaps, as well as an incision. The application of a caustic may also some- times be advantageously resored fo when there is a good deal of indolent hardness around a small abscess. The calx cum polassa, or the potassa alone, is the best caustic for opening abscesses. The part is first to be covered with a piece of adhesive plaster, which has a portion cut out exactly of the same figure and size as the opening intended to be made in the abscess. The best way of making the eschar is to dip the end of the caustic in water, and to rub it on the part till the skin becomes brown. The active substance is then vo be immediately washed off with some wet tow, the plaster is to be removed, and an emol- lient poultice applied. In almost all cases, it is better to use the lancet, or double-e iged bistoury. Either of these instruments opens the abscess at once, and with less pain, than results from the use of caustic; it occasions no loss of substance, consequently a smaller cicatrix ; and, by using it, the opening may be made in the most advantageous direction, and of the exact size required. DRESSINGS AFTER OPENING ABSCESSES. When an abscess has burst of itself, and it is unnecessary to enlarge the opening, the only thing requisite is to l^ep the surround- ing parts clean. The continuation of the same kind of poultice, which was before used, is, perhaps, ns good a practice as any ; and when the tenderness, arising from the inflammation, is over, lint and a pledged may be made use of, instead of the poul- tice. But, an abscess, opened by a cutting in- strument, is both a w r ound and a sore, and partakes more of the nature of a fresh wound in proportion to the thickness of the parts cut. Hence, it is necessary that some- thing should be put into the opening to keep it from healing by the first intention. If it is lint, it should be dipped in some salve, which will answer better than lint alone, as it will allow of being taken out sooner. This is advantageous, because such sores should be dressed the next day. or at latest on the second day, in order that the pus may be discharged again. When the cut edges of the opening have suppurated, which will be in a few days, the future dressings may be as simple as possible, for nature will, in gene- ral, complete the cure. If the abscess has been opened with caus- tic, and the slough has either been cut out: or separated of itself, the case is to be re- garded altogether as a suppurating sore, and dressed accordingly. Perhaps, dry lint is as good a dressing as any, till the nature of the sore is known. If it should be of a good kind, the same dressing may be continued*; but, if not, then it must be dressed accordingly. Parts, which at first appear to be sound, some- times assume every species of disease, whether from indolence, from irritability, from scrofulous, and other dispositions. This tendency to disease arises, in some ca- ses, from the nature of the parts affected, as, for instance, bone, ligament, &o. (Hun- ter.) Consult particularly John Hunter's Trea- tise on.the Blood , Inflammation, nnd Gunshot Wounds , a work, in which more interesting knowledge respecting Abscesses and Suppura- tion is contained, than in any other ever pub- lished. See also Traite de la Suppuration de F Ouesnay, 1749. J Grashuis, A Diss. on Suppuration, 8 vo. Load. 1752. Various parts of the Memoir es de 1' Academic de Chi- r /rgie. J B Boyer , De Suppuratione et Cu- ratione Inflammatvmis per Suppuralionem ter- minandee. Monsp. 1766. U Encyclopedic Me thodique. Partie Chirurgicale, article Abces. Dissertations on Inflammation by John Burns, 1800. Sir E Home's Dissertation on the Properties of Pus , 1788 ; and his Pract. Obs. on Ulcers, 2d Edit. 1S01 James Hendy, Essay on Glandular Secretion, containing an experimental Inquiry into the Formation of Pus, fyc.8vo. Loud. 1775. JY. Romayne, De Puris Generatione,8vo. Edinb. 1780. C. Dar- wins Experiments, establishing a criterion be- tween mucilaginous and purulent matter, fyc. Litchfield, 1780. P. Clare, Essay on Abscesses. Loud. 1781. Several parts of Poll's Chirurgi- cal Works, but especially his Treatise on the Fistula in Ano. T. Brand , Strictures in Vin- dication of some of the Doctrinesmisreprcsented by Mr. Foot in his two pamphlets, entitled “Ob- servations upon the new opinions of J. Hunter , in his Treatise on the Venereal, including Mr. Pott' Plagiarisms, and misinfomal'bv p*r. SURGERY. 4.41 Pus," fyc. 4 to. Load. 1787. Richter, Anfangs- griinde der Wundarzneykunst, B. 1, Kap. 2. Dr. J. Thomson's Lectures on Inflammation, p. 305. tyc. Edinb 1813 ; a work, in which a profound knowledge of medical science, and of surgery in particular , is every where con- spicuous. J. F. Crevecwur, De Diagnosi Puris ; Longchamps, 1793. Pearson's Prin- ciples of Surgery, p. 34, §'C. Edit. 2. Lassus Pathologic Cfururgicale. T 1 , p. 21, fyc. fyc. Edit, of 1809. Stb.J. Brugmans, De Puo- genia, sive mediis quihus naturautitur in cre- au do pure, 8vo. Groningce, 1785. Dr. G. Pearson s ' ibs . and Experiments on Pus in the Philosophical Trans, for 1811. C. J. M. Langenbeck, Von der Behandiung der Fistel- gttnge, der Schusscanale , und grosser Eiter absonderndtr Holden, in Neue Bibl. far die Chirurgie, 12mo. Hanover, 1817. SURGERY, or C 111 RURGERY, (derived from chirurgeon, from the hand, and s e,yov, work,) has been by many considered to be that branch of medicine, which prin- cipally effects the cure of diseases by the application of the hand alone, the employ- ment of instruments, or the use of topical remedies. (Encyclopedic Mcthodique, Padie Chir. Tom. I, Art. Cliirurgie.) But, although this definition certainly conveys to us some idea of the nature of this most useful pro- fession, it is not entirely accurate as applied to the present state of practice. It might, indeed, be correct during that short unfa- voured period of surgery upon the conti- nent, some centuries ago, when its practice was denounced by the Council of Tours, as unfit for the hands of priests and men of literature, and when the surgeon became little better than a sort of professional ser- vant to the physician, the latter alone not only having the sole privilege of prescribing internal medicines, but even that of judging and directing when surgical operations should be performed. Then the subordi- nate surgeon was only called upon to exe- cute with his knife, or his hand, duties which the more exalted physician did not choose to undertake ;.and, in fact he visit- ed'the patient, did what was required to be done, and took his leave of the case alto- gether under the orders of his master. In modern times, however, the good sense of mankind has discovered that surgery is de- serving of an eminent rank among such arts as ought to be cultivated for the gene- ral benefit of society ; that the man who is not himself accustomed to the performance of operations, cannot be the best judge of their safety and necessity j and that, in every point of viewy the surgical practition- er merits as much favour and independence in the exercise of his profession, as he whose avocation is confined to physic. Hence, the surgeon is now exclusively con- sulted about many of the most important diseases to which the human body is liable. Being no longer under the yoke of the phy- sician, he follows the dictates of his own judgment and knowledge ; he prescribes whatever medicines the case may demand, internal as well as external ; and under the Vor,, 11 encouragement of an enlightened age, he sees his profession daily becoming more scientific, more respected, and more exten- sively useful. By some writers, physic is said to have for its object the treatment of internal, surgery that of external diseases. This definition, however good and plausible it may at first appear, can only be received with numerous exceptions in regard to modern surgery : for instance, the psoas abscess, stone in the bladder, an extravasa- tion of blood withiritheskullin consequence of accidental violence, are universally allow- ed to be strictly chirurgical cases ; yet no man in his senses would call these disorders external. Others have defined surgery to be the me- chanical part of physic, “ quod in therapeia mechanicum but, although this has obtain- ed the assent of so eminent a modern sur- geon as Professor Richerand, of Paris, (Did. des Sciences Medicates, Tom. 5, p. 85.) I believe few on this side of the water will be of his opinion. As Mr John Pearson has observed, “ Many people have imagined that when a man has learnt the art of dress- ing sores, of applying bandages, and per- forming operations with a little dexterity, he must necessarily be an accomplished surgeon. If a conclusion so gross and falla- cious had been confined to the vulgar and illiterate, the progress of scientific surgery would have suffered little interruption ; but if young minds are directed to these objects, as the only important matters upon which, their faculties are to be exercised ; if the gross informations of sense constitute the sum of their knowledge, little more can be expected from such a mode of study, than servile imitation, or daring empiricism. In- deed, some people have affected to oppose surgery as an art, to medicine as a science ; and if their pretensions w T ere justly founded, the former would certainly be degraded to a mere mechanical occupation. But it is not very easy to comprehend the grounds of such a distinction. The internal and external parts of the body are governed by the same general laws during a state of health ; and, if an internal part be attacked with inflammation, the appearances and effects will bear a great similarity to the same disease situated externally ; nor are the indications of cure, in general, materi- ally different. If by science, therefore, be meant ‘ a knowledge of the laws of nature,* he who knows what is known of the order and method of nature, in the production, progress, and termination of surgical dis- eases, merits as justly the title of a scienti- fical practitioner as the well-educated phy- sician. The practical parts of physic and surgery are very frequently disunited ; but their theory and principles are indivisible, since they truly constitute one and the same science.” (Pearson's Principles of Surgery , Preface.) But, though we can object on good grounds to the above-mentioned definitions of surge- ry. it seems impossible to offer any other. SURGERY •142 against „which equal objections could not be brought. Tn fact, how is it possible to define surgery with any degree of accuracy, until the boundaries between it and physic can be determined ? Richerand talks indeed of the Medical School of Paris having now successfully established the limits and 'ob- jects of surgery, and he boasts of this as an original improvement reflecting credit on his countrymen. (See Did. des Sciences Med. T. 5, p. 88.) Yet, what are we to think, when we remember, not only that he has, in the commencement of the very same article, defined surgery to be u quod in therapeia mechanicum ” but that by way of illustrating what the Parisian School has accomplished, he says, that surgery was first demonstrated by it to be only a means of physic, and not a separate and distinct science ? (See also Dicl. des Sciences Med. article Chirurgicales , Maladies.) As a learned Professor notices, the limits between physic and surgery are not very precisely marked, and the respective func- tions of the physician and surgeon, long as those names have existed, are still but very * ^accurately defined. “The most superfi- cial acquaintance with the symptoms, pro- gress, and termination of the various mor- bid affections to which the human body is liable, must be sufficient to convince every unprejudiced inquirer, that there is but a slight foundation, if indeed there be any, for this distinction, in the nature of the dis- eases, which these practitioners are required to treat, or in the modes of treatment, by which the diseases themselves may be cured or relieved. Experience has long shown, that the use of internal remedies is not only required in a large proportion of the diseases, which are regarded as strictly chirurgical, but also, that there are few diseases, which come under the care of the physician, in which morbid affections, requiring the manual aid, or practical skill of the surgeon, do not fre- quently occur. “ The treatment of febrile and internal inflammatory diseases, it will be allowed, belongs exclusively to the province of the physician, w herever the distinction between physician and surgeon has been introduced, and is rigidly observed ; yet, in some species of fevers, and in all internal inflammatory diseases, blood-letting is often the principal, if not the only remedy that is required. But this is an operation, however urgent the necessity for it be, which from engagement the physician cannot, and, from the fear of degrading his province of the profession, will not perform. Retention of urine not unfrequently takes place in symptomatic febrile diseases, and this is an affection which does not always yield to the use of internal remedies; but it is an affection also, from the painful uneasiness, which it immediately excites, as well as from the dan- ger which it threatens, that will not admit of delay. When internal remedies, therefore, fail in relieving the patient, the urine must be speedily drawn off by means of a chirur- gical operation ; otherwise inflammation, mortification, and rupture of the bladder, must necessarily ensue. Febrile and in- ternal inflammatory affections terminate not unfrequently in the formation of fluids, w hich it is necessary to let out by a chirur- gical operation ; and abscesses, fistulous openings, and ulcers are formed, which re- quire the aid of the surgeon. In patients, also, affected with severe febrile diseases, from being long fixed down to their beds in one position, some of the parts of the body, upon which they rest, occasionally acquire a disposition to mortify, larger or smaller portions of the skin and subjacent cellular membrane becoming dead, separate from the living parts, and sores are formed, wffiich are but too often the subject of unavailing chirurgical practice. To employ, in the different stages of this species of mortifica- tion, from its first commencement to the complete separation of the dead parts, and the formation of a new r skin, the appropri- ate external and internal remedies, requires a greater share of chirurgical skill than can reasonably be expected in those who make a profession solely of physic. Unhappy, therefore, must be the lot of that patient, who in circumstances similar to those w'hich I have described, has the misfortune to have for his sole medical attendant, a physician ignorant of surgery. “ Bui (continues Professor Thomson , ) if a knowledge of surgery be necessary to the student who intends to practise physic, the knowledge of physic, on the other hand, is no less necessary to him w r ho intends to> devote his attention exclusively to the pro- fession ot surgery; for, indeed, there are few chirurgical diseases, which are not in some period or another of their existence, accompanied by mobid affections of the same nature with those which fall properly, and most frequently under the care of the physician. It will only be necessary to men- tion, as examples of these affections, the symtomatic fever, which attends inflamma- tion, whetherthis affection has been induced by external injury, or has occurred spontane- ously in the body from internal disease ; the hectic fever, supervening to long-continued processes of suppuration ; the febrile state and other morbid affections, which are some- times brought on by the too sudden and in- judicious use of mercury ; bilious fevers, and the various derangements of the di- gestive organs, which are sometimes the cause, and at other times the consequence, of local diseases ; the nervous affections, such as apoplexy, convulsions, paralysis, and mania, which arise not unfrequently from injuries of the head ; and locked jau r , or tetanus, which, in warm climates parti- cularly, is so very liable to be induced by punctured wounds. These are morbid af- fections, the proper study and treatment of which, when they occur without local inju- ry, are supposed to belong to the physiciu.% rather than the surgeon ; but occuring very frequently as they do in chirurgical diseases, and always modifying, or aggravating, the SUHGEKi «tfects oi these diseases, ignorance of their nature, relations, and modes of cure, is not only inexcusable, but highly criminal in the practitioner, who ventures to undertake their treatment.” ( Thomson's Lectures on Inflammation , Introduction. Also J. R. C. Bollman, Tentamen, ostendens Chirurgiam a Medicina hand impune separari, 12 mo. Rintel , 1803.) From what has been stated, I think it very certain, that there never can be a com- plete scientific division of the healing art into physic and surgery ; and that all at- tempts to distinguish the numerous diseases and injuries of the human body into medi- cal and surgical cases, must in a great mea- sure be decided by custom, and the mutual agreement of practitioners, rather than by any rules, or principles, which are at all consistent. In the earliest periods, the same men cultivated the whole field of medicine. The writings of Hippocrates, Galen, Celsus, Pau- ius (Egineta, Albucasis, &c. prove that the Greeks, Romans, and Arabians never had an idea of the human body being susceptible of only two classes of diseases, one of which formed the province of physic, while the other constituted a separate and distinct science called surgery. All these ancient authors treat successively of fevers, frac- tures, wounds, and nervous diseases, and none of them appear to have supposed, that there could be any disorders which really deserved to be called external , and others internal. Nor was it until the middle of the twelfth century, that the ecclesiastics were restrained from undertaking any bloody ope- ration. Surgery was then rejected from the universities, under the empty pretext, “ Ec clesia abhorret a sanguine ,” often expressed in its decrees, as Professor Thomson well observes, but never acted upon, except in this instance, by the church of Rome. It is to this epoch that we must refer the true separation of physic from surgery, the latter being abandoned to the laity, who, in those ages of barbarism, were totally illiterate. It is an observation made by the celebra- ted Bichat, that two things are essentially necessary to form a great surgeon, viz. genius and experience. One traces for him the way, the other rectifies it ; both recipro- cally assist in forming him. Without expe- rience, genius would be unprofitably fertile ; without genius, experience would only be a barren advantage to him. ( CEuvres Chir. de Desault , par Bichat, T. 1, Discours Prelim.) Out of the large number of hospital surgeons, who are to be met with in every country of Europe, and who enjoy ample opportunities of profiting by the lessonsof experience, bow few distinguish themselves, or ever contri- bute a mite to the improvement of their profession. Opportunity, without talents and an aptness to take advantage of it, is not of more use than light to a blind man. On the other hand, splendid abilities, with- out experience, can never be enough to make a consummate surgeon, any more than a man with the greatest genius for painting can excel in his particular art with- out having examined and studied the real objects which he wishes to delineate. In short, as a sensible writer has remarked, “ Les grands chirurgiens sont aussi rares, que le gdnie, le savoir, et les talens.” (Mem. de V Acad, de Chir. T. 1, Pref. p. 41, Edit. 12 mo.) The description of the qualities which a surgeon ought to possess, as given by Celsus, is excellent as far as it goes. A surgeon^ says he, should be young, or, at any rale, not very old; his hand should be firm and steady, and never shake ; he should be able to use his left hand with as much dexterity as his right ; his sight should be acute and clear; his mind intrepid and pitiless, so that when he is engaged in doing any thing to a patient, he may not hurry, nor cut less than he ought, but finish the operation, just as if the cries of the patient made no impression upon him. Ul. C. Celsi Med. Prcef. ad lib. 7.) By the word “ immisericors ,” as Richerand has observed, ( JYoscgr . Chir. Tom. 1, p. 42, v Edit. 2,) Celsus did not mean that a surgeon ought to be quite insensible to pity; but that during the performance of an operation, this passion should not influence him, as all emotion would then be mere weakness. This undisturbed coolness, which is still more rare than skill, is the most valuable quality in the practice of surgery. Dexterity may be acquired by exercise ; but firmness ot mind is a gift of nature. Haller, to whom nature was so bountiful, in other respects, was denied this quality, as he candidly con- fesses. “ Although (says he) I have taught surgery seventeen years, and exhibited the most difficult operations upon the dead body, I have never ventured to apply a cutting in- strument to a living subject, through a fear of giving too much pain.” (Bibl. Chir. 1775;, Vol. 2.) Surgery may boast of having had an ori- gin, that well deserves to be called noble, for the earliest practice of it arose from the most generous sentiment which nature has implanted in the heart of man, viz. from that sympathetic benevolence, which leads us to> pity the misfortunes w T hich we behold, and inspires us with an anxious desire toalleviate them. He who first saw his fellow-creature suffer could not fail to participate in the pain, and endeavour to find out the means of affording relief. Opportunities of exercising this useful inclination were never wanting. In the first ages of the world, man in his des- titute state was under the necessity of earn- ing by force or stratagem, a subsistence which was always uncertain, and in the combats into which this sort of life drew him, he frequently met with wounds and other injuries. Wherever the chace was in vogue as a means of livelihood or amuse- ment ; wherever broils and contests occa- sionally arose ; and man was the same ani- mal he now is, liable to various diseases and accidental hurts ; there must have ex- isted a necessity for c urgery ; nor can there SURGERY 444 be a doubt, that the origin of this valuable practice is as ancient, as the exposure of mankind to several of the same kinds of in- juries, as befall the human race at the pre- sent day. At length wars became more frequent and extensive; wounds were conse- quently multiplied; and the necessity for surgical assistance was increased, and its value enhanced. In fact, among the ancients, the profes- sion of medicine and surgery constituted a sacred kind of occupation, and the practice of it belonged only to privileged persons. JEsculapius was the son of Apollo. In the armies, the highest princes gloried in dress- ing the wounds of those who had fought the battles of their country. Among the Gre- cians, Podalirius, Chiron, and Machaon, were not only distinguished for their valour, but also for their skill in surgery, as we learn from the poem of the immortal Homer. The value which was placed upon the ser- vices of Machaon by the Grecian army may well be conceived from the anxiety which they evinced to have him properly taken care of when he was wounded in the shoul- der with a dart. “ O Nestor, pride of Greece, (cries ldomeneus) mount, mount upon thy chariot! and let Machaon mount with thee! Hasten with him to our ships ; for a warrior, who knows, as he does, how to relieve pain, and cure wounds, is himself worth a thou- sand other heroes.” (See Iliad , lib. xi.) Hip- pocrates was one of the first citizens of Greece ; he nobly refused all the rich offers of several kings, enemies of his country, to entice him into their service ; and, in parti- cular, he disdained to accept those of Xerxes, whom he regarded as a barbarian. It is in the immortal poems of the Iliad and Odyssey, that we find the only certain traditions respecting the state of the art be- fore the establishment of the republics of Greece, and even until the time of the Pelo- ponnesian war. There it appears that sur- gery was almost entirely confined to the treatment of wounds, and that the imaginary power of enchantment was joined with the use of topical applications. In the cures recorded in the sacred wri- tings of the Christian religion, the interven- tion of a supernatural power is always com- bined with what is within the scope of hu- man possibility. The same character evinces itself in the infancy of the art in every na- tion. The priests of India, the physicians of China and Japan, and the jugglers of the savage or half-civilized tribes of the old and new continents, constantly associate with drugs and manual operations certain myste- rious practices, upon which they especially rely for the cure of their patients. Such was also, no doubt, the character of the medicine of the Egyptians, in the remote times, previous to the invention of the alpha- bet, and upon which so very little light is now thrown. It is curious, however, to find, from some late observations made by the men of science, who accompanied the French ex- pedition to Egypt, in 1798, that, among the ruins of ancient Thebes there are documemB, which fully prove that surgery, in the early limes of the Egyptians, had made a degree of progress, of which few of the moderns have any conception. It is noticed by Lar- rey,that when the celebrated French Gene- ral Desaix had driven the Mamelukes beyond the cataracts of the Mile, the Commission of Arts had an opportunity of visiting the monuments of the famous Thebes, and the re- nowned temples of Tentyra, Karnack,Medy- net, Abou, and Luxor, the remains of which still display their ancient magnificence. It is upon the ceilings and walls of these tem- ples that basso-relievos are seen . representing limbs that had been cut off with instruments very analogous to those which are employed at the present day for amputations. The same instruments are again observed in the hieroglyphics, and vestiges of other surgical operations may be traced, proving that, in these remote periods, surgery kept pace with the other arts, which had already attained a high degree of perfection. ( Larrey , Me- moir es de Chir. Militaire, T. 1, p. 233 ; T. 2, p. 223.) We next come to the epoch when, by the union and arrangement of scattered facts, the science truly arose. Hippocrates, born in the island of Cos, four hundred and sixty years before the common era, collected the observations of his predecessors, added the results of his own experience, and composed his first treatises. In the hands of this great genius, medicine and surgery did not make equal progress. The former reached the highest degree of glory. Hippocrates drew up the history of acute diseases in so mas- terly a style, that twenty past centuries have hardly found occasion to add any thing to the performance. But surgery was far from attaining the same degree of perfection. The religious veneration for the asylums of the dead, and the impossibility of dissecting the human body, formed an insurmountable obstacle to the study of anatomy. An im- perfect acquaintance with the structure of animals, reputed to bear the greatest resem- blance to man, could only furnish venture- some conjectures, or false inferences. These circumscribed notions sufficed for the study of acute diseases. In these cases, the atten- tive observation of strongly-marked symp- toms, and the idea of the operation of a sa- lutary principle, derived from remarking the regular succession of such symptoms, and their frequently beneficial termination, en- lightened the physician in the employment of curative means ; while surgery, deprived of the assistance of anatomy, was too long kept back in an infant state. Whatever praises may have been bestowed on those parts of the works of Hippocrates particu larly relating to surgery, and which amount to six in number (de ojirina medici ; de frac- turis ; de capitis vulneribvs; de articulis vel luxatis ; de ulceribus; de Jistulis;) when com- pared with his other acknowledged legiti- mate writings, they appear only as the rough sketches of a picture by a great master. Excepting the fragments, collected or sURGERY M6 cited by Galen, we possess no work written by any of the successors of Hippocrates un- til the period of Celsus ; which leaves a bar- ren interval of almost four centuries. In this space lived Erasistratus, as well as He- rophilus, celebrated for the sects which they established, and particularly for having been the first who studied anatomy upon the hu- man body. Celsus lived at Rome in the reigns of Au- gustus, Tiberius, and Caligula. He appears never to have practised the healing art, on which, however, he has written with much precision, elegance, and perspicuity. His work is the more precious, inasmuch as it is the only one, which gives us information, with regard to the progress of surgery in the long interval between Hippocrates and him- self. The four last books, and especially the seventh and eighth, are exclusively al- lotted to surgical matter. I he style of Celsus is so elegant, that he has generally been regarded quite as the Cicero of medi- cal writers, and long enjoyed high reputation in the schools. His surgery was entirely that of the Greeks, notwithstanding he wrote at Rome : for, in that capital of the world, physic was then professed only by persons who had either come from Greece, or had received instruction in the celebrated schools of this native soil of all the arts and sciences. Let us pass over the interval which sepa- rates Celsus and Galen This latter was born at Pergamus in Asia Minor, and came to Rome in the reign of the emperor Marcus Aurelius. He practised surgery and physic there about the year 165 of the Christian era. ( Galeni Opera Omnia , 1521, Edit. Aldi , 5 Vols. in fol .) These two sciences were at that time still united, and though some wri ters of much earlier date speak of the divi- sion of physic into dietetical, chirurgical, and pharmaceutical, no such distinction w as followed in practice. As Galen had been a surgeon at Pergamus, he continued the same profession at Rome ; but, being soon attract- ed by the predominating taste of the age in which he lived, for a science which more easily yields to the systems and dazzling speculations of philosophical sects, he after- ward neglected surgery which strictly re- jects them. His writings prove, however, that he did not abandon it entirely. His commentaries on the treatise of Hippocrates, De Officina Medici , and his essay on banda- ges, and the manner of applying them, show that he was well versed even in the minor details of the art. Besides it is known. that he paid great attention to pharmacy, and in his work upon antidotes, chap 13* he tells us himself, that he had a drug shop in the Via Sacra, which fell a sacrifice to the flames that destroyed, in the reign of Corn- modus, the Temple of Peace, and several other edifices. To Galen succeeded the compiler Oriba- sius, (Etius of Amida, a physician, who lived towards the close of the fifth century, Alex- ander of Tralles, and Paulus (Egineta, so called from the place of his birth, though he practised at Rome and Alexandria. Paulus collected into one work, still justly esteem- ed, all the improvements, which had been made in surgery up to his own time. He concludes the series of Greek and Roman physicians, and may be looked upon as the last of the ancients, unless it be wished to let the Arabians have a share in the honours of antiquity. “He appears, says Portal, to be one of those unfortunate writers, to whom posterity has not done justice. It seems as if he had been decried without having been read ; for if pains had been taken to examine his works, he would neither have been re- garded as a mere copyist, nor been called the “ape of Galen,” with whom he does not always coincide. Nay, in some places, he ventures to oppose the doctrines of Hippo- crates. He was perfectly acquainted with the practice of the ancients, and when he agrees with, or differs from them, it is not from a spirit of contradiction, but because the reasons, which led him to take one side, or the other, appeared to him well founded.” {Portal, Hist, de VAnat. fyc. T. 1, p. 123.) All now agree, that surgery is much indebted to him. (See R. A. I’ogtl , De Pauli (Egineta , Meritisin Medicinam imprimisque Chirurgiam, 4 to Golt. 1768.) Afterward the downfall of surgery followed tbatof all the other scien- ces, and from thecaptureof the Alexandria by the Saracens under Amrou, viceroy of Egypt, 1641, until the end of the tenth century, nothing prevailed but the dark clouds of ig- norance and barbarism. The Arabians, who became masters of a great part of the Ro- man empire, dug up the Greek manuscripts, which lay buried under the ruins of the li- braries ; translated them ; appropriated to themselves the doctrines which they con- tained ; impoverished them with additions ; and transmitted 1o posterity only enormous compilations In a word, such are the trea- tises of Rhazes, Hali- Abbas, Avicenna, Aver- rhoes, and Albucasis, the most celebrated of the Arabian authors. Inventors of a prodi- gious number of instruments and machines, they appear to have calculated the efficacy of surgery by the richness of its arsenals, and to have been more anxious to inspire terror, than confidence. As an instance of the cruelty of their methods, I shall merely notice, that, in order to stop the bleeding after amputation of a limb, they plunged the stump in boiling pitch. The fate of medicine was not more for- tunate. In vain the school of Salernum, founded about the middle of the seventh century, made some attempts to revive its splendour. As a modern writer observes, medical science, seated on the same benches where the doctrine of Aristotle, accommo- dated to religious opinions, was the subject of endless controversies, imbibed, as it were by contagion, the argumentative and so- phistical mania, and became enveloped in the dark hypotheses of scholastic absurdity. {Richer and, Nosogr. Chir. T. 1, Ed. 2.) The universal ignorance (continues this author ;) the pretended horror of blood ; the dogma of a religion which shed it in tor- rents for useless quarrels; an exclusive re SURGERY. iish for the subtleties of the school, and speculative theories ; are circumstances fur- ther explaining the profound darkness which followed these empty labours. About the middle of the twelfth century, (1163,) the Council of Tours prohibited the ecclesias- tics, who then shared with the Jews the practice of medicine in Christian Europe, from undertaking any bloody operation. It is to this epoch that the true separation of medicine from surgery must be referred. The latter was abandoned to the laity, the generality of whom, in those ages of barba- rism, were entirely destitute of education. The priests, however, still retained that portion of the art which abstained from the effusion of blood. Roger Rolandus, Bruno, Gulielmus de Salicetus, Lanfranc, Gordon, and Guy de Chauliac, confined themselves to commentaries on the Arabians, and if the latter author be excepted, they all dis- graced surgery by reducing it nearly to the mere business of applying ointments and plasters. Guy de Chauliac, however, the last of the Arabians, is to be honourably ex- cluded from such animadversion. His work written at Avignon, in 1363, in the pontifi- cate of Urban the fifth, to whom he was physician, continued to be, for a long while', the only classical book in the schools. It may be observed, that as he imitated in eveiy respect the other Arabian physicians, and like them thought that it did not be- come an ecclesiastic to deviate from the austerity of his profession, he passed over In silence the diseases of women. Atlength Antonio Beneveni, a physician of Florence, began to insist upon a truth, of the highest importance to the extension of surgical knowledge, viz. that the compi- lations of the ancients and Arabians ought to be relinquished for the observation of nature. ( De abditis rerum causis, Florent. 1507, 4to.) A new era now began. The moderns were convinced, that by treading servilely in the footsteps of their predeces- sors, they should never even equal, much less surpass them. The labours of Vesalius also gave birth to anatomy, illuminated by which science, surgery put on quite a dif- ferent appearance in the hands of Ambroise Fare, the first and most eminent of the French surgeons. For the credit of Italy, however, it should be recorded, that the sensible writings published in that country prior to the time of Par6, had the greatest influence in creating a due sense of the value and importance of surgery, and in disposing men of talents and education to cultivate it as a liberal profession. Obeying the dictates of his genius, Par6 made authority yield to observation, or sought to reconcile them. However, his superior merit soon excited the ignorant, the jealous, and the malignant against him ; he became the object of a bitter persecution, and his discoveries were represented as a crime. Although he was the restorer, if not the inventor, of the art of tying the blood-vessels, the power of his persecutors compel! ed bint to make imperfect extracts from Galen, and alter his text, in order to rob himself, in favour of the ancients, of the glory which this distinguished improvement deserved. Surgeon of King Henry the second, Fran- cis the second, Charles the ninth, and Henry the third, of France, Pare practised his pro- fession in various places, followed the French armies into Italy, and acquired such esteem, that his mere presence in a besieged town was enough to reanimate the troops employed for its defence. In the execrable night of Saint Bartholomew, his reputation saved his life. As he was of the reformed religion, he would not have escaped the massacre, had not Charles the ninth himself undertaken to protect him. The historians of those days < Mem de Sully ) have pre- served the remembrance of this exception, so honourable to him who was tile object of it; but which should not diminish the just horror which the memory of the most weak and cruel tyrant must ever inspire. u II n’en voulut jamais sauver aucun (says Bran- tome) siuon maistre Ambroise Pare, son premier chirurgien, et le premier de la chr6- tiennetfi ; et l’envoya querir et venir le soir dans sa chambre et garderobe, lui comman- dant de n’en bouger ; et disait qu’il n’etait raisonnable qn’un qui pouvait servir h tout un petit monde, feust ainsi massacre.” Ambroise Pare was not content, like his predecessors, with exercising his art with reputation ; he did not follow the example of the Quatre-Maitres of Pitard, so justly celebrated for having composed the first statutes of the College of Surgeons at Paris, -in the reign of St. Lewis, whom he had at- tended in his excursions to the Holy Land ; and of several other surgeons, the fruits of whose experience were lost to their suc- cessors. Par6 transmitted the result of his own experience in a work that will remain immortal. (See (Euvres d' Ambroise Par£ y Conseiller et premier Chirurgien du Roi , di - visees in 28 livres , in folio , Edit. 4 to. Paris, 1535.) His writings, so remarkable for the vari- ety and number of facts in them, are emi- nently distinguished from all those of his time, inasmuch as the ancients are not looked up to in them with superstitious blindness. Freed from the yoke of autho- rity, he submitted every thing to the test of observation, and acknowledged experience alone as his guide. The French writers are with reason proud of their countryman Pai6 to this day : they allege, that he must ever hold among surgeons the same place that Hippocrates occupies among physi- cians. Nay, they add, that perhaps there are none, either of the ancients or moderns, who are worthy of being compared with him. (Richerand JVosogr. Chirurg. T. 1.) After the death of this great man, surgery, which owed its advancement to him, con- tinued stationary, and even took a retro- grade course. This circumstance is alto- gether ascribable to the contemptible state into which those who professed the art fell SURGERY. 447 alter being united to the barbers by the to the grave the secret of hi's admirable in- most disgraceful association. jections. (See also his Thesaur. Anat. x. in Pigrai, the successor of Ambroise Part% 4 to. Adversariorum anatomicorum medico - was far from being an adequate substitute chirurgicorum Decad. 3, in 4 to. Amstelodam .) for him. A spiritless copyer of his master, Roonhuysen also made a secret of his lever, he abridged his surgery in a latin work, which, before the invention of the forceps, where the unaffected graces of the original, was the only resource in difficult labours, the sincerity, and the ineffable charm inse- Raw, who successfully cut fifteen hundred parable from all productions of genius, en- patients for the stone took such pains to tirely disappeared. He received, however, conceal his manner of operating, that Heis- equal praise from his contemporaries ; ter and Albinus, his two most distinguished doubtless, because, he filled a high situation ; pupils, have each given a different explana- but, as Richerand remarks, his name, which tion of it. Such a disposition, which was is to-day almost forgotten, proves sufficient- extremely hurtful to the advancement of ly, that dignities do not constitute glory. surgical knowledge, would materialy have Rousset and Guillemeau distinguished retarded the progress of surgery in Holland, themselves, however, in the art of mid- had not Camper, in the following century, wifery, while Covillard, Cabrol, and Habi- effaced this imputation by the great number cot enriched surgery w r ith a great number of his discoveries, and his zealous desire to of curious observations, (~ee Obs. Chir. make them public. pleines de remarques curieuses, Lyon, 1639, While great improvements were going on in 8 vo. Alphabet Anatomique, Gen&ve, 1602, in Italy, England, and Holland, surgery fan in 4 to. Semaine Anatomique; Question guished in a humiliated state in France Chir. sur la Bronchotomie, Paris, 1620, The accoucheur Mauriceau ( Trait6 des Ma- in 8v o.) ladies des Femmes grosses , Paris, 1668, in In the next or seventeenth century, a 4/o.) Dionis, (Cours d’ Operations de Chi- fresh impulse produced additional improve- rurgie, Paris, 1707, 8vo.) Saviard, inents. Then appeared in Italy, Ca?sar veau Recueil d'Obs. Chir. Paris, 1702, in Magatus, who simplified the treatment of 12mo.) and Belloste ( Chirurgien d’Hopital, wounds, (de rarct vulnerum medicalione, Paris, 1696, in 8vo.) were the only French libri 2, Venet. 1616, in folio ;) Fabriciusab surgeons of note who could be contrasted Aquapendente, even less praise-worthy as a with so many distinguished men of other surgeon than as a physiologist, ( Opera nations. Richerand observes, that the splen- Chir. Paris, 1613 in fol. ;) and Marcus Au- did days of Louis the Fourteenth were an relius Severinus, that restorer of active sur- iron age for discouraged surgery. And yet gery. Dt ejfficac) Medicina , libri 3, Franco - this monarch seems to have been personally furt, 1613, in folio. De recondita abscessu- interested in the melioration of this irapor- um natura libri 7, Koapoli, 1632, in 4 to taut art ; for he was very nearly falling a and Trimembris ( hirurgia . ^c. Franco fur t. victim to a surgical disease, a fistula in ano, 2653, in4to.) Among the English surgeons and was not cured till after a great number flourished Wiseman, w ho was the Pare of of blundering operations and useless experi- England (See Several Chinirgical Treatises, ments. Lond. 1676, in fol.;) and William Harvey, Chronology teaches simply the history of whose discovery of the circulation of the dates. In the study of the sciences, the blood had such an influence over the ad- only method of impressing the memory vancement of surgery, that he must be class- with facts, consists in connecting the epoch cd among the principal improvers of this °f them with the learned men by whom science. (See Exercitatio Anatomica de they have been illustrated. But the great- motu cordis et sanguinis in animalibus, F>an - est surgeons of the eighteenth century have cofurti, 1653, in 4to.) In Germany, Fabri- not altered the face of their profession, eius Hildanus, (Obs. et Curationum, Cen although they have powerfully contributed turitzG, 2 Vol.in4to. 1641) who was far to its advancement. In surgery, as an au- superior, as a surgeon, to the Italian Fabri- thor has remarked, some feeble rays always cius Scultetus, so well known for his work, precede brilliant lights, and it approaches entitled Armamentarium Chirurgicwn ; Ul- perfection in a very gradual way. In the mce, 1653, in folio. Purmann and Solingen, last century, however, among the distin- whohad the fault of being too partial to the guished surgeons of France, there are two use of numerous complicated instruments, of extraordinary genius, round whom, as it (See Cursre Obs. Chir. Lipsice, 1710, in 4 to. were, all the others might be grouped and Mqnuale Obs. der Ckirurgie, Amsterdam, arranged, and whose names deserve to be 1684, in 4to.) affixed to the two most brilliant epochs of Holland, restored to liberty by the gene- French surgery. These are, first, J. L. rous exertions of its inhabitants, did not Petit, whose glory was shared by the Aca- remain a stranger to 4 the improvement of demy of Surgery; and, secondly, the cele- surgery. This nation, so singular in many brated Desault. respects, presents us with one particularity It is not with surgery, as with physic, which claims the notice of a medical bisto- strictly so called ; the epochs of the latter nan, Ruysch, who was an eminent ana- are distinguished by hypotheses ; while those tomist, and merits equal celebrity for his of surgery are marked by discoveries. The Obs. Anatomico- Chirurgicorum Centuriae, eminent men in this last branch of the pro Amstelodam. 1691, in 4to . carried with him fession have not? like the most renowmed SURGERY. **48 physicians, created sects, built systems, de- stroyed those of their predecessors, and con- structed a new edifice, which in its turn has been demolished by other hands. All of them have been satisfied with combating an- cient errors, discovering new facts, and con- tinuing their art, the sphere of which they have enlarged by their discoveries, without making it bend under the yoke of systems, which it would have ill supported. To this steady and uniform course, (says Richerand,) which is a striking proof of the superiority of surgery, and of the certainty and invaria- bleness of its principles, shall we oppose the numerous revolutions of physic ? The Chris- tian religion, which abounds in sects, has not a greater number of them than physic. fs'a- turi-tes, solidistes, humoristes, vitalistes, ani- misies, semi-animistes, mecaniciens, chi- roistes; le plus grand nombre des medecins honore Hippocrate d’un culte presque super- stitieux ; ceux-ci marchent sous les ban- nieres de Staahl ; ceux-las’*ppuient du grand nom de Boerhaave ; tels autres invoquenl Sydenham, Hoffmann, Stoll, absolument comcne les iheologiens combattent pour Lu- ther, Zuiugle, Calvin, ou Jansen.” ( Nosogr Chir. T. 1.) The elogy on J. L. Petit, delivered in the midst of the Royal Academy of Surgery, of which he was one of the first and most dis- tinguished members, represents him as blend- ing the study of anatomy with his amuse- ments when a boy ; and ardently seeking ever, opporl unity to increase his knowledge by observaiion. He had had experience enough to publish at an early period of his life his Traitd sur les Maladies des Os, Paris, 17o5, in l'2mo. ; a work which for a centu- ry was esteemed the best upon the subject. His success was most virulently opposed by the envious critics; and it was uot till after more than thirty years of academical labours an t extensive practice, that he was unani- mously chosen the head of hisassociates. This acknowledged superiorly, however, was the more flattering, as the honour was obtained at a period when surgery was in a flourishing state in France, and when Petit held no of- fice, from which he could derive an influence foreign to his peisonat merit. While Mares- chal. La Peyronie, and La Martiniere assured him of the royal favour, Quesriay, Morand, and Louis, who corrected his writings, made him speak a language which does honour to that famous collection, to which he contribu- ted his observations, (>ee Mimoires et Prix de l' Academic Royale de Chirurgie, 10 Pols, in 4 to.) and in which, it some theoretical ex- planations be put out of consideration, no- thing lias lost its value by age. J. L. Petit was al o the author of a “ Traile des Mala- dies Chirurgicaies et des Operations qui leur conviennent. Outrage Podhume ;" a pro- duction that will always sl *nd high in the estimation of the judicious surgeon. The history of this epoch, so glorious for the profession of surgery, is completely de- tailed in the Me moires and Prix of the Royal Academy of Surgery ; a work which is ab- solutely indispensable, and the various parts of which cannot be too often considered. In it are preserved the labours of Mareschal, Quesnay, La Peyronie, Morand, Petit, De la Martiniere, Le Dran, Garengeot, De la Faye, Louis, Verdier, Foub> rt, Hevin, Pibrac, Fa- bre, Le Cat, Bordenave, Snbatier, Puzos, Levret, and several other practitioners, who, though less famous, contributed by their ex- ertions and know ledge to form this useful body of surgical facts. Many of the prece- ding surgeons also distinguished themselves by other productions, which, however, I shall not here enumerate, as they are quoted in many other parts of this work. To the foregoing list of eminent French surgeons, must be added the names of La Motte, Maim-Jean, Goulard, Daviel, Rava- ton, Mejean, Pouteau, David, and Frere Cosme. While surgery was thus advancing in France, other nations were not neglectful of it. At this period flourished in England, White, Cheselden, Douglas, the two Monros, Sharp, Covvper, Warner, Alanson, Percival Pott, Hawkins, Suiellie, and the two Hun- ters. White’s Cases in Surgery, 1770: Chesel- den’s Treatise on the High Operation for the Stone, London, 1723 in Hvo. ano his Treatise on the Anatomy of the Human Body ; Dou- glas’s Tract, entitled. Lithotomia Douglass - iana;" Sharp’s Treatise of the Operations ; and his “ Critical Inquiry into the present State of Surgery Monro's Works by his son; Warner's Cases in Surgery, 1754, and his Description of the Eye and its Diseases, 1775; Alanson' s Treatise on Amputation; Pott’s Chirurgical Works ; Smellie's Midwife- ry ; and John Hunter on the Blood, Inflam- mation, fyc. ; his Treatise on the Venereal Disease ; Animal Economy , the Teeth, and all the papers written by himself and his brother, in the Phil. Trans. Med. Obs. and Inquiries , and Trans, of a Society for the Im- provement of Med. and Chir. Knowledge ; are productions which reflect the highest credit on the state of surgery in England. But of all these eminent men, none con- tributed more powerfully than Mr. Percival Pott, to the improvement ot the practice of surgery in England. His life, indeed, forms a sort of epoch in the history of the profes- sion. Before his inculcations and example had produced a desirable change, the maxim of “ dolor medicina doloris ,” as we learn from Sir James Earle, remained unrefuted. The severe treatment of the old school, in the operative part and in the applications, continued in force. The first principles ot* surgery, the natural process and powers of healing, were either not understood, or not attended to ; painful and escharoiic dress- ings were continually employed; and the actual cautery was iiLsuch frequent use, that at the times wuen Ine surgeons visitej the hospiial, it was regularly heated, and prepa- red as a necessary part of the apparatus. Where shall we find more sensible, or more truly practical observations on the treatment of abscesses, than in his excellent treatise ou the fistula in nuo ? Where shall we meet with &LRGERY '449 belter remarks on the local treatment of gan- grenous parts, than in his valuable tract on tthe mortification of the toes and feet ? What author abounds with so many just observa tions on the injuries of the head, blended, it is true, with rather too great a partiality to the trepan, the so frequent necessity for which is now less generally acknowledged ? His description of the inflammation and suppu- ration of the dura mater, and of the treat- ment, is matchless. The account which he has left us of the disease of the vertebra?, at- tended with paralysis of the limbs, is per- haps his most original production. His ce- lebrated essay on fractures, was also very original, and has had in this country consi- derable influence over the treatment of these injuries ; but there can now be no doubt, that the effects of position were exaggerated 5n this part of bis writings, and that surgeons ought still to make every possible exertion to render their apparatus for broken bones more effectual. (See Fractures.) A more peally valuable production of this eminent surgeon is his remarks on amputation. The necessity for that operation in certain cases is there convincingly detailed ; and the most advantageous period for its performance clearly indicated. The urgency for its prompt execution, after particular injuries, he has indeed so perfectly explained, that the late inculcations on the subject by Larrey, and several other modern surgeons, appear to be in a great measure anticipated ; the only dif- ference being, that Pott’s remarks applied principally to compound fractures, while Larrey’s refer to gunshot wounds. All these, however, are cases of accidental violence, and of course should be treated upon the same general principles A longer comment on the writings and improvements of Percival Pott would here be requisite to do him every degree of jus- tice; but his name, advice, and opinions are so conspicuous throughout this volume, that 1 shall be excused for not saying any thing more in the present place, than that he was in his time, the best practical surgeon, the best lecturer, the best writer on surgery, the best operator, of which this large metropo- lis could boast. Another character of still greater genius and originality, though of inferior education, was the ever memorable John Hunter, sur- geon to St. George’s Hospital, who was at once eminent as a surgeon, an anatomist, a physiologist, a naturalist, and philosopher. If Pott materially improved many parts of the practice of surgery in England, and evinced himself to be the most skilful ope- rator of his time, John Hunter was also not less importantly employed in extending the boundaries of physiological knowledge, and in the investigation of human, and particu- larly comparative anatomy. The knowledge which he derived from his favourite studies, fie-oonstantly applied to the improvement of the art of surgery, and he omitted no oppor- tunity of examining morbid bodies, whereby he collected facts which are invaluable, as Vol. II 57 they tend lo explain the real causes of (he symptoms of numerous diseases. In the practice of surgery, whenever ope rations proved inadequate to their intention, Mr. Hunter always investigated with uncotn rnon zeal the causes of ill success, and in this way he detected many fallacies, as well as made some important discoveries in the healing art. He ascertained the cause of failure, common to all the operations in use for the radical cure of the hydrocele, and was enabled to propose a mode of operating attended with invariable success. He ascer tained, by experiments and observations, that exposure to atmospherical air, simply, can neither produce nor increase inflamma- tion. He discovered in the blood so many phenomena connected with life, and not to be referred to any other cause, that he con- sidered it alive in its fluid state. He impro- ved the operation for the fistula lachrymalis, by removing a circular piece of the os un- guis, instead of breaking it down with the point of a trocar. He explained better than any of bis predecessors, all the highly inte- resting modern doctrines relative to inflame (nation, union by the first intention, suppura- tion, ulceration, and mortification. His writings also throw considerable light on the growth, structure, and diseases of the teeth As instances of his operative skill, it deserves to be mentioned, that he removed a tumour from the side of the head and neck of a pa- tient at St. George’s Hospital, as large as the head to which it was attached ; and by bring- ing the cut edges of the skin together, the whole wound was nearly healed by the first intention. He likewise dissected out of the neck a tumour, which one of the best opera- tors in (his country had declared, rather too strongly, that no one but a fool or a mad- man would meddle with ; and the patient got perfectly well. But perhaps the greatest improvement which he made in the practice of surgery, was his invention of a new mode of performing the operation for the popliteal aneurism, by taking up the femoral artery on the anterior part of the thigh, without open ing the tumour in the ham. (See Trans, of a Society for the Improvement of Med ^ and Chir. Knowledge.) The safety and efficacy of this method of operating have now been fully established, and the plan has been ex tended to all operations for the cure of this formidable disease. (See Aneurism.) According to Sir Everard Home, Mr. Hunter was also one of the first who taught, that cutting out the bitten part was the only sure mode of preventing hydrophobia ; and he lengthened the time in which this pro- ceeding might be reasonably adopted, be- yond the period which had been generally specified. His researches into the nature of the ve- nereal disease, and his observations on the treatment, will for ever be a lasting monu raent of his wonderful powers of reasoning and investigation. If he left some points of the subject doubtful and unsettled, he has admirably succeeded in the elucidation of others : and his work on this interesting di- SURGERY . order, is, with ail its defects, the best which is jet extant. Even (he language and mode of expression of this great man were his own ; for so ori- ginal were his sentiments, that they could hardly be delineated by any ordinary arrange- ment of words. His phrases are still adopt- ed in all the medical schools of this country, and continue to modify the style of almost every professional book. Great as Mr. Hun- ter’s merit as a surgeon was, it was stdl great- er as a comparative anatomist and physiolo- gist. The museum of the Royal College of Surgeons, and his papers in the Phil. Trans, will for ever attest hts greatness in these cha- racters. At the period, when the preceding distin- guished men upheld the character of their profession in Great Britain, Lancisi, Mor- gagni, Molinelli, Bertrandi, Guattani, Mas- cagni, Matani, Troja. and Moscati, were doing the same thing in Italy. Bertrandi’s Treatise on the Operations of Surgery, and Troja’s Work on the Regeneration of Bones, are even at this day works of the highest repute. Of late years, the credit of the Ita- lian surgeons has been honourably main- tained by Monteggia, Scarpa, Paletta, Qua- dri, Assalini, Morigi, and others. In Hol- land flourished Albinus, Deventer, Sandi- fort, and Camper; and in Germany, and the north of Europe, the immortal Haller, Heister, well known for his “ Institutiones ChirurgicB Piatner; Rcederer ( Elemtnla Artis Obstetricicc. Goeit. 1752. Obs. de Partu Laborioso. Decad. 11, 1756.) stein, Bilguer, Acrell, Callisen, {System a Chirurgice Hodi- crnce , 2 Vol. 8 vo.) Brambilla, Thecien, ( Pro - gres ulterieurs de la Chirurgie.} Sch mucker, ( V crmischte Chvrurgische Sckriften, B. 3, and Chir. Wahrnchmungf,n.) Richter, ( Traite des Hernies, 2 Vol.&vo. Bibl. fur die Chirurgie ; Ansfangsgr. der Wundarsn. 7 B. and Obs. ChirurgicaruniFa.sc.) Also Arnemann, Weid- niaun, Beer, Soemmering, Creutzenfeldt, Hesselbach, Idufeland, Graefe, Klein, Him- iy, Langenbeck, Walther, J A. Schmidt, G. J. Beer, &c. should not be forgotten, seve- ral of whom are still pursuing their useful and honourable career. Be it also record- ed as a part of the great merit of the Ger- mans, that they now rank among the best and most minute anatomists ; that they are zealous cultivators of comparative anato- my ; that their industry allow s no improve- ment in medical science, wherever made, to escape their notice ; and that surgery is greatly indebted to them for the best descrip- tions of the diseases of the eye. On the continent, the Academy of Surge- ry at Paris was long considered quite as the solar light of this branch of science. The French Revolution, which, by a fatal abuse, involved in the same prohibition both use- ful and pernicious societies, did not spare even this beneficial establishment. Al- though the Academy was deprived of the talents of Louis, who died a short time be- fore its suppression, it yet had at this period several members, worthy of continuing its labours, and supporting its reputation : Sa- batier, Desault, who may be regarded ay the Pott of France, Chopart, Lassus, Pey- rilhe, Dubois, Percy, Baudeloque, Pelletan, Sue, &c. The Academy of Surgery in France was succeeded by what is named the Ecole de Medecine. Desault, who was almost a stran- ger in the former, became quite the leading character in the latter. Several things re- commended him strongly to the remem- brance and admiration of posterity ; the ex- actness and method which he introduced into the study of anatomy ; the ingenious kinds of apparatus which he invented for the treatment of fractures,.; a noble ardour in his profession, which he knew how to impart to all his pupils ; his clinical lectures upon surgery, "which were the first ever de- livered ; and the boldness and simplicity of bis modes of operating. Indeed, such was his genius, that even when he practised only methods already understood, he did them with so much adroitness, that he rather ap- peared to be the inventor of them. From the Ecole de Medecine have issued Dupuy- tren, Boyer, Richerand, Dubois, Lheritier. Manoury, Lallemant, Petid de Lyon, Bi- chat, &c. The researches of Bichat, who quitted surgery, powerfully contributed to the ad- vancement of physiological science. His mind, richly stored with the positive facts which he had learned in the study of surge- ry, conceived no less' a project than that of rebuilding the whole edifice of medicine. Some courses of lectures upon the materia medica, internal clinical medicine and mor- bid anatomy, announced this' vast design, which was frustrated by a premature death. Bichat, as a physiologist, and man of very original genius, may be consideral as the John Hunter of France; but his qualities were of a different cast, and hardly admit of comparison with those of Hunter, whose investigations were not limited to man, but extended to the whole chain of animated beings. Bichat died in the midst of his la- bours, and in dying his greatest regret was that of not having completed them. His example, says Richerand, proves most con- vincingly what Boerhaave always inculcu ted, how indispensable the study and even the practice of surgery are to him, who would wish to be a distinguished and sue cessful physician. (Nosogr. Chir. Tom. 1, p. 25.) Perhaps nothing contributed so materially to the improvement of surgical knowledge, as the establishmentof the Royal Academy of Surgery in France; anomie institution, which, fora long while, gave our neighbours infinite advantage over us, in the cultivation of this most useful profession. Indeed, every one truly interested in the improvement of sur- gery, cannot fail to regret the discontinu- ance of a society, in which emulation and talents were so long united for the benefit of mankind. The various dissertations pub- lished by the illustrious members of the aca- demy, will serve as a perpetual memorial of the spirit, ability, and success, with which SURGER\ the objects of the institution were pursued ; and centuries hence, practitioners will reap from the pages of its memoirs the most va- luable kind of surgical information. Unfor- tunately, this establishment, which was overthrown by ihe agitation of the French Revolution, has had only a very inferior substitute in the Ecole de Mfidecine Were l to name any one thing, which, in my opioion, would have the greatest influ- ence in giving life to the study and cultiva- tion of surgery in this country, I should without hesitation assign such importance to the establi-hment of an institution in the metropolis, on the same grand, liberal, and encouraged plan, as the late Royal Acade- my of Surgery in France. At the same time, 1 am conscious that the present Medical and Chirurgical Society of London have every claim to the encourage- ment and gratitute of the profession. No other institution of the kind has ever done so much in so short a space of time. Many of the facts which they have collected and published, are of considerable importance, especially those relating to the subj'ects of aneurism and hemorrhage. Their library is already the most select, valuable, and com- plete collection of medical literature in Great Britain ; and it is daily receiving ad- ditions both by large purchases at borne and abroad, and by the liberal donations of its members. The intercourse and correspond- ence ^hich such a society continually main- tain among the innumerable scattered mem- bers of tbe profession, cSnnot fail to be at- tendedwith the most beneficialconsequences. A generous and useful sort of emulation is thus kept alive ; the spirit of inquiry is pre- vented from slumbering ; and every indivi- dual vrho ascertains a new fact, has now the means of making it known to the world, with all the expedition which its import- ance may demand. Within the last twenty or thirty years, most important improvements have certain- ly been made in almost every branch of surgery; and it must gratify every English- man to find, that his own countrymen have acted a very leading part in effecting an object, in which the interests of mankind are so deeply concerned. Before the time of Mr. John Hunter, onr ideas of the venereal disease were surround- ed with absurdities ; and it is to this lumi- nary that we are in an eminent degree indebted for the increased discrimination and reason, which now prevail, both in the doctrines and treatment of the complaint. It must be confessed, however, that much yet remains to be made out. respecting the nature and treatment of syphilitic disorders. Need 1 mention a greater proof of the truth of this remark, than the sudden change of practice in some of the principal hospitals in London, mercury being now not exhibited in more than one out of ten cases, for which this medicine a few years ago was always deemed indispensable ? Numerous cases, having all the characters of primary' vene- real sores, seem now to be curable by sim- 401 pie dressings and cleanliness. In short, so different is every thing from what it used to be, that many surgeons are tempted to sup- pose the nature of the venereal disease to tally (altered. Some observations on this important topic are offered in another place. See Venereal Disease. Strictures in the urethra, an equally com- mon and distressing disease, were not well treated of before Mr. Hunter published on the venereal disease ; at*d the advantage of armed bougies in the treatment of certain cases has been subsequently pointed out by Sir Everard Home. In modern times, hernial diseases, those common afflictions in every country, have received highly interesting elucidations from the labours of Pott, Camper, Richter, Sir Astley Cooper, Hey, Gimbernat, Hes- selbach, Scarpa, Lawrence, he. The treatment of injuries of the head has been materially improved by Quesnay, Le Dran, Pott, Hill, Desault, and Aber- nethy. I he disease of the vertebra?, which oc- casion* paralysis of the limbs, formerly al- ways baffled the practitioner; but the me- thod proposed by Air. Pott is now frequently productive of considerable relief, and some- times of a perfect cure. The diseases of the joints in general may also be said to be at present viewed with much more discrimina- tion than *hey were a veryfew r years ago; and this great step to better and more successful practice reflects great honour on Mr. Brodie, while it keeps up a well-founded hope, that morbid anatomy, the study which has of late banished so much confusion from this part of surgery, will yet be the means of bring- ing to light other useful fact^ and observa- tions, relative to the diseases of the joints in general. The mode of treating lumbar abscesses has been rendered much more successful than formerly, and for this change the world is in- debted to Mr/ Abernethy. The almost infallible plan of curing hy- droceles by an injection, as described by Sir James Earle, may also be enumerated among modern improvements. The increasing aversion to the employment of the gorget in lithotomy, and the many dis- tinguished advocates for the use of better in- struments in this operation, may be hailed as propitious omens of beneficial changes in this part of practice. The diseases of the eyes, to which affec- tions English surgeons seemed to pay much less attention than was bestowed by foreign practitioners, now obtain due attention in this country. Although we have generally had some distinguished oculists, our regular surgeons have generally been wonderfully ignorant of this part of their profession, and uninformed on the subject, they have given up to professed oculists and quacks one of the most lucrative and agreeable branches of practice. However, the able writings of Daviel, Wenzel, and Ware, begin now to be familiarly known to practitioners: and the observations of Scarpa, Richter, Beer, SURGERY Wardrop, Travers, and Saunders, will soon have immense effect in diffusing in the pro- fession a due knowledge of the numerous diseases, to which the organs of vision are liable. As likewise the generality of the hospital surgeons of London, have, during the last thirty years, grossly neglected the study of the diseases of the eye, and consci- entiously refused to have any thing to do with these cases, the public at length saw the necessity of establishing Eye Infirma- ries, where such afflictions might be more attentively observed and relieved. Some of these have now become excellent schools, in which the rising generation of surgeons have abundant opportunities of studying the nature of all the diseases of the eyes, and the most approved methods of treatment. While, however, 1 am thus commending separate institutions for disorders of the eye, it becomes me to express my regret for the long-continued neglect, and the ignorance of these diseases, manifested by several hospital surgeons, which were in fact the original causes of those distinct establish- ments. For, according to my conceptions, it would have been far better to have had the practice in eye-cases exhibited in the common great schools of surgery, the large hospitals of London. 1 am of this opinion, not only because I think these diseases would then have met with more general and public observation ; but also because I have always considered all unnecessary sub- divisions of practice, in short all measures which tend to throw particular cases into the hands of a few individuals, hurtful to the best interests, and degrading to the charac- ter of the profession. In the treatment of aneurisrnal diseases, English surgeons have much to be proud of. All the boldest operations in this branch of surgery have been devised by the genius, and executed by the spirit and skill of British surgeons. Even M. Roux himself is here obliged to confess our superiority. ( Paral - lele de la Chirurgie Angloise , fyc. p. 249.) The carotid artery, the external and internal iliac, and the subclavian, have all been suc- cessfully tied by surgeons of this country. The first operation, in which the external iliac was tied, I was a spectator of : it was performed by Mr. Abernethy in Bartholo- mew’s hospital, and it has subsequent!) been repeated in many examples, both iri this country and others, with considerable suc- cess. I bad also the honour of seeing the same gentleman likewise tie the carotid, in the first instance of that operation in Eng- land. This important measure has also now been frequently practised with success, and it constitutes one of the great improvements in the operative part of modern surgery. In the article Aneurisoi, I have cited many examples, in which the carotid artery has been successfully tied ; and the safety and propriety of the operation are now ge- nerally known and acknowledged. Indeed, so little are surgeons now afraid of the ill effects upon the brain, that the carotid arte- ry has lately been tied merely for the purpose of enabling the operator (o fake away a large tumour, including the whole of the parotid gland, from the side of the neck, without risk of hemorrhage ; a mode of proceeding, however, which ought not to be encouraged into a common practice. (See Medico-Chir . Trans. Vol. 7, p. 112.) Before 1 quit this subject, my feelings call upon me to express tbe high opinion which I entertain of Mr Hodgson’s Treatise on the Diseases of Arte- ries and Veins, published in 1815, a work which reflects great credit on English sur- gery, and contains practical precepts far su perior to those of Scarpa. In the modern practice of surgery, a variety of old prejudices are gradually va- nishing. Peruvian bark not many years ago, was regarded as a sovereign remedy and specific for nearly all cases of gangrene „ and in these and many other instances, it was prescribed without any discrimination, and in doses beyond all moderation. But the false idea, that this medicine has any specific effect in checking mortification, no longer blinds the senses of the most superfi- cial practitioner. He neither believes this doctrine, nor tbe still more absurd opinion, that strength can be mysteriously ex- tracted from this vegetable substance, and communicated to the human constitution, in proportion to the quantity which can be made to remain in the stomach. This sub ject, however, has been duly discussed in the articles Cinchona and Mortification. The removal of this deeply-rooted pre- judice, concerning the virtues of bark, in stopping mortification, will pave the way to better and more successful practice. But upon the subject of mortification, the present day opens to us the investigation of a point, which is of the first-rate conse- quence. Every surgeon is aware, that when a limb is affected with mortification, ampu tation is absolutely necessary to effect a cure. This is generally acknowledged; but the performance of the operation has, since the time of Mr. Pott, only been sanctioned when the mortification has manifestly ceased to spread, and a line of separation is formed between the dead and living parts. All other instances, in which the disorder was in a spreading state, were left to their fate It is true, some of tbe old surgeons occasion - ally ventured to deviate from this precept , but as they did so without any discrimina- tion, or knowledge of the particular exam- ples which ought to form an exception to the general rule, their ill success cannot con- stitute a just argument against the plan of amputating earlier in a certain description of cases. Now if modern experience can prove, that many lives may be saved by a timely performance of amputation, under circum- stances in which it has until lately been ge nerally condemned, it must be allowed that the established innovation will be one of the greatest improvements in the practice of the present time. For reviving the consideration of this question, and venturing to deviate from the SURGERY beaten path, the world is much indebted to that eminent military surgeon, Baron Lar- rey. How different his doctrines and prac- tice are from those usually taught in the schools, the article Mortification will suffi- ciently prove. In the treatment of ununited fractures, the simple and ingenious practice proposed by Dr. Physick of Philadelphia, merits particu- lar notice, not only on account of the seve- ral successful trials which have been made of it in this country and France; (See Me- dico- Chir. Trans. Vols. 5 7, and Buyer's Trait6 des Maladies Chir.) hut also because it is perhaps the first improvement of con- sequence, that has hitherto been made in the practice of surgery by our transatlantic brethren. The inestimable treatise of Dr. Jones on Hemorrhage, has now produced quite a re- volution in all the principles, by which the surgeon is guided in the employment of the ligature for the stoppage of bleeding and the cure of aneurisms. Instead of thick clumpy cords, small firm silks or threads, are now generally used; and so far is the practitioner I from being fearful of tyjng arteries too tight- f ly, lest the ligature cut through them, that it is now a particular object with him to apply the silk or thread, with a certain degree of force, in order that the inner coat of the ves- i sel may be divided. If this be not done, the effusion of coagulating lymph within the ar- tery, an important part of the process of ob- literation, cannot be expected as a matter of certainly, and secondary hemorrhage is more likely to occur- But in order to con- vey an adequate idea of the beneficial changes which Dr. Jones’s observations are tending to produce in practice, we have been careful in the article Hemorrhage, to give a tolerably full account of the results of all his interesting experiments. Besides using very small, firm, round threads, instead of large fiat tapes or cords, t as was the custom a few years ago, modern surgeons begin to suspect, that much benefit may also arise from cutting off both portions of the ligature close to the knot, after am- putation, the removal of the breast, &c. ]\o one has insisted so much as Mr. Lawrence upon the propriety of examining further the merits of this innovation. If no bad effects result from leaving so small a particle of ex- traneous substance in the flesh, as the- little bit of silk composing the knot and noose on 1 the artery, the practice will form a consider- able improvement. The wound may then be brought together at every point ; the quantity of extraneous matter in the wound i will be lessened to almost nothing ; the dan- 1 ger of convulsive affections w ill bp reduced i in proportion as a serious cause of pain or irritation is diminished ; and the chance of accomplishing perfect union by the first in- tention will be materially increased. Mr. Lawrence has tried the plan in many instan- ces, and hitherto his experience has not found any ill consequences follow, while it lias proved, that many advantages are un- i doubtedly the result of it. In amputations, 453 the method has been practised by several of our military surgeons ; and although they have probably not employed exuctly such ligatures as this mode absolutely requires, the greater part of them have met with hard- ly any instances of future trouble from the bits of ligature enclosed in the wound. However, if larae ligatures be used, the prac- tice is not lairly tried, or rather the practice is not tried at all; because the great princi- ple, on which it answers, is the very small atom of silk composing the extraneous sub- stance left in the wound, when such liga- tures as Mr. L .vvrence particularly recom- mends are employed. Delpech and Rous have also sometimes adopted the plan of re- moving the ends of the ligature close to the knot. (See Parldlble de la Chir. Angloise avec la Chir. Fanqoise, p. 131.) See Ampu- tation, Aneurism , Hemorrhage , and Liga- ture. Among other real improvements in mo- dern practice, I must not forget the present more rational method of dressing the wound, alter the majority of capital operations, with light, cooling applications, instead of laying on the part a farrago of irritating’ pledgets and piasters, and a cumbersome mass of lint, tow, flannel, and other banda- ges, woollen caps, &c. The fewer the adhe- sive strips are the better, if they bold the lips of the wound together. This is all they are intended to do. Whereas, if you apply more than are necessary for this purpose, they do harm by heating the part, and co- vering the wound so entirely as to prevent the issue of the discharge. Over the adhe- sive plasters, let the surgeon be content with, placing a simple pledget of spermaceti cerate, and some linen wet with cold wa- ter, which will often avert hurtful degrees of pain and inflammation, by keeping the parts cool. Wars, which are unfavourable to most other sciences, are rather conducive to ad- vances in surgery. The many new and in teresting observations which Baron Larrev has made in the course of his long and ex tensive military experience, are a proof of the foregoing remark. Pitard, almost the founder of surgery in France, was a milita ry surgeon. Ambrose Paieand Wiseman also collected their most valuable knowledge principally in the service of the army. Mr. Hunter himself gained much of bis practical information in the same line of life. To Baron Larrey surgeons are indebted for many highly important observations, relating to amputation in cases of gunshot wounds. In particular he has adduced a larger and more convincing body of evidence, than was ever before collected to prove, that in gunshot injuries, the operation of amputation should always be performed without the least delay, in every instance in which such operation is judged to be unavoidable, and the ullimate preservation of the limb either impossible, or beyond the scope of all rational probabi lity. He has established the truth of this most important precept in military surgery by innumerable facts, drawn chiefly from 454 SU3 his own ample experience, and partly from the practice of many able colleagues. The great operations of the shoulder-joint, and hip-joint amputations, he has executed w ith success. The necessity for the former, however, he proves may sometimes be su- perseded, and the limb be saved, by making a suitable incision for the extraction of the splintered portions of the upper part of the humerus. This method, which was in many instances done with success in the peninsu- lar war was, 1 believe, originally proposed and practised by Boucher. (See Mem. de I'Acad. de Chir. T. 2, Ato.) However, it was more particularly described and even practised by Mr, C. White, of Manchester. (See his Cases in Surgery.) It has been re- peated wiib success by Mr. Morell in the York Hospital. (See Med. Chir. Trans. Vol. 7.) See Amputation. Amputation at the hip-joint, performed only in the most dreadful cases, because itself the most dreadful operation in surgery, Bar m Larrey has performed five limes, and twice (I believe) with success. This pro- ceeding has also been adopted by Mr Brownrigg and Mr. Guthrie, and their pa- tients ^recovered. As must be the case, however, on account of the desperate cir- cumstances under which the operation is performed, and the severity of the operation itself, the examples of recovery bear only a small proportion to the large number of deaths, known to have followed amputation at the hip in the many cases, in which it has now been undertaken. However, the un- fortunate truth should not be exaggerated into a reason for a general condemnation of the practice, which is adopted as the only means affording a chance of life. But as there may he diffic dty in deciding whether the patient will have the best chance with or w ithout the operation, it is to be hoped that no sur- geons will perform it, except under the authority of ;be united opinion of a board, or consultation of the best-informed practition- ers, whom circumstances will allow to assem- ble. See Amputation. In military surgery, the useful innovation of ambulances, or light caravans, furnished with a proper number of surgeons, assist- ants, and orderlies, and capable of keeping up with the vanguard, if requisite, is un- doubtedly the best means of affording speedy surgical assistance to the w'ounded on the field of battle, and ought to be enumerated as one of the greatest modern improvements Barons Percy and Larrey deserve the chief praise for their successful exertions in organi- zing and bringing to perfection so indispensa- ble mi establishment. The account of this subject well deserves perusal ; and ii may be s en eiiher in Larrey' s Mtmoires de Chi- rurgie Militaire, or in tht Diet, des Sciences Mi icales, T. 5 SUSPENSORY. A bandage for support- ing the scrotum ; a bag-truss. Bandages of this kind are now usually sold at the shops, and seldom made by surgeons themselves ; therefore a particular description of them is not. essential in this work. In cases of her- Sti’l nia humoralis, varicocele, cirsoceie, some, particular ruptures, and several other affec- tions of the testicle, and spermatic chord, a suspensory bandage is of infinite service. SUTURES, (from suo, to sew.) A suture, in surgery, means a mode of uniting the edges of a wound, by keeping them in con- tact with stitches. Mr. Sharp remarks, that “ when a wound is recent, and the parts of it are divided by a sharp instrument, without any further vi- olence. and. in such manner, that they may be made to approach each other, by being returned with the hands, they will, if held in close contact for some time, reunite by inosculation and cement, like one branch of a tree ingrafted on another. To maintain them in this situation, several sorts of su- tures have been invented, and formerly practised, but the number of them has, of late, been very much reduced. Those mow chiefly described are the interrupted , the glover's, the quilled, the hoisted, and the dry , sutures : but the interrupted and twisted are almost the only useful ones, for the quilled suture is never preferable to the interrupted ; the dry suture is ridiculous in terms, since it is only a piece of plaster, applied in many different ways, to reunite the lips of the wound ; and the glover’s, or uninterrupted stitch, which is recommended in superficial wounds, to prevent the deformity of a scar, does rather, by the frequency of the stitches, occasion it, and is therefore to be rejected, in favour of a compress and sticking plaster. 5 ( Oper . of Surgery.) The twisted suture is described in speaking of the harelip ; and gaslroraphe, w hich also properly belongs to the present subject, forms a distinct article in this Dictionary. Interrupted Suture. — The wound being cleansed from all clots of blood, and its lips being brought evenly into contact, the needle, armed with a ligature, is to be care- fully carried from without inwards to the bottom, and so on from within outwards G’are must be taken to make the puncture far enough from the edge of the wound, lest the ligature should tear quite through the skin and flesh. This distance, according to Mr. Sharp, may be three, or four-tenths of an inch. The other stitches required are only repetitions of the same process. The threads having beeu all passed, “ you are in general to begin tying them in the middle of the wound ; though, if the lips be held carefully together, (says Mr. Sharp,) it will not be of great consequence, which stitch is tied first.” ( Operations , Chap. 1.) Surgical writers in general state, that the number of stitches must, in a great measure, depend upon the extent of the wound. The common rule is, that one suture is sufficient for every inch of the wound ; but that in some instances, a stitch must be more fre- quently made, particularly when a wound gapes, very much, in consequence of a trans- verse division of muscles. As w'e have al- ready explained, it is necessary to pierce the skin, at a sufficient distance from the sides of the wound, lest the thread should cut SUTURES. Too* through the flesh in a short time : but, though Mr. Sharp lays down the necessary distance, in general as three, or four-tenths of an inch, and others advise the needle to be always carried through the deepest part of the wound, we must receive these directions, particularly the last, as subject to numerous exceptions. When a wound is very deep, it would be conspicuously absurd, and even, in many instances, dangerous, to drive the needle through a vast thickness of parts. Other wounds, of considerable length, might not be, in some places, four-tenths of an inch deep ; though it is true, sutures could never be requisite at such points. The needles for making the interrupted suture will pass with the greatest facility, when their shape corresponds exactly with the segment of a circle, and they should al- ways form a track of sufficient size to allow the ligatures, which they draw after them, to pass through the flesh with the utmost ease. The interrupted suture obviously receives its name from the interspaces between the stitches ; and it is the one most frequently employed. Its action is alw T ays to be assisted and supported, either with the uniting ban- dage, (see Bandage ) or with strips of adhe- sive plaster, compresses, &e. Quilled Suture. — As Mr. John Bell has observed, “ when the wound was deep among the muscular flesh, the old surgeons imagined, that so large a wound could not be commanded by the common interrupted suture, how r ever deep the stitches might be driven among the flesh ; they were besides ' fearful of using the continued (glover’s) su- ture in deep gashes, lest the wound should be made to adhere superficially, w'hile it w as still open within, forming perhaps a suppu ration, or deep collection of matter They believed, that a deep muscular wound could not be safely healed, without a degree of suppuration ; while they wished to bring it together at the bottom, they were afraid to close it very exactly at the mouth, lest the matter should be collected in the deeper parts of the wound ; it was for this purpose (says Mr. John Bell) that they used what they called the compound , or quilled suture. It is merely the interrupted suture, w r ith this difference, that the ligatures are not tied over the face of the wound, but over two quills, or rolls of plaster, or bougies, which are laid along the sides of the wound. In performing this suture, we make first two, three, or four stitches, of the interrupted suture very deep, and then, all the ligatures being put in, we lay two bougies along the sides of the wound, then slip one bougie into the loop of the ligatures on one side, drawing all the ligatures from the other side, (Mr. Bell should rather have said towards the other side,) till that bougie is firmly bra- ced down. Next we lay the other bougie, and make the knots of each ligature over it, and draw' it also pretty firm ; and thus the ligatures, in form of an arch, go deep into the bottom of the wound, and hold it close, while the bougies, or quills, keep the mid- dle of the wound, and lips of it pressed to- gether with moderate closeness, and prevent any strain upon the threads, or any coarse and painful tying across the face of the wound.’’ In a note Mr. J. Bell says, that Dionis violently reprobates the quilled su- ture; but, that De la Faye (the annotator on Dionis) says, it is good for deep muscular wounds. The quilled suture is now scarcely ever employed ; nor has it any advantages, except, perhaps, in some wounds in the belly. (See Principles of Surgery, Vol. \,p. 50 .) I think the reader will more easily com- prehend the manner of making the quilled suture, from the following simple directions. Take as many needles, as stitches intended to be made ; arm them with a double liga- ture, or one capable of being readily split into two ; introduce the ligatures through the wound ; cut off the needles : lay a piece of bougie along one side of the wound, and tie the ends of the ligatures over it. Next draw the other extremities of the ligatures, so as to bring the first piece of bougie into close contact with the flesh ; lay the second piece of bougie along the opposite side of the wound, and tie the other ends of the li- gatures over it with sufficient tightness. Glover's Suture. This had also the name of the continued suture. It was executed by introducing the needle first into one lip of the wound, from within outw ards, then into the other in the same w ay ; and, in this manner the whole track of the wound was sewed up. The glover’s suture has long been rejected by all good surgeons, as improper to be em- ployed in cases of common wounds. It was not, however, till very lately, that this suture was totally abandoned; for JVJr. Sharp, and several eminent writers since his time, have advised its adoption in wounds of the stomach and intestines. From what has been said in the articles Wounds of the Abdo- men and Hernia, the reader will perceive, that even in such particular instances, the glover’s suture would not be adviseable ; so that it may, in every point of view, be now considered as totally disused in every case of surgery which can possibly present itself. When we remember, in making this suture, how many stitches are unavoidable ; how unevenly, and in w hat a puckered state the suture drags the edges of the skin together, and what irritation it must' produce, we can no longer be surprised at its now being ne- ver practised on the living subject. It is commonly employed for sewing up dead bodies; a purpose for which it is well fitted, but for the honour of surgery, and the sake of mankind, it is to be hoped that it will never again be adopted in practice. False, or Dry Suture . — Modern surgeons commonly understand by this expression nothing more, than the plan of bringing the sides of a wound together, by means of adhesive plaster ; nor did Mr Samuel Sharp attach any other meaning to the phrase, wTjich he sets dowm as highly ridiculous, as there is no sewing employed. For the 456 • SUTURES following remarks, i am indebted to Mr. Carwardine, of Earls Colne Priory, near Halsted, Essex. Alluding to what was sta- ted in the last edition of this Dictionary, concerning the dry suture, he observes, e( you do not appear to be aware any more than Mr. Sharp, of the precise mode of its application, or why it was so called. In- deed, it is a curious circumstance, how this method of dry suture should have been so lost, as not to be described by any modern surgeons, who laugh at the very term, speak- ing of it as a mere application of a strip of adhesive plaster. In the sulura sicca, so call- ed in opposition to the sulura crumta, where blood followed the needle, some ad- hesive plaster was spread on linen, having a selvage. A piece of this was applied along each side of the wound (the selvages being opposed to each other,) and then drawn together by sewing them with a com- mon needle, without bloodshed. Hence the term sulura sicca. The dry suture was used in all wounds of the face to avoid scars. You will find it thus described by our countryman Thomas Gale in his Enceiridion, 1563 ; and also by A. Pa- rey, who gives a figure of it in his folio work, 1579.” I feel much obliged to my friend Mr. Carwardine for this explanation, without which the expression dry suture is undoubtedly absurd. As the common way of dressing wounds with sticking plaster will come under consideration in a future part of this work, (see Wounds,) I shall not here detain the reader upon that topic. Sutures, by which I mean such as were made in the flesh with a needle and ligature, were much more frequently employed by the old surgeons, than they are by the moderns. The best practitioners of the present day never resort to this method of holding the sides of a wound in contact, except in cases in which there is a real necessity for it, and other modes will not suffice. There were, indeed, certain instances, in which the employment of sutures was long ago forbidden. Of this kind were enve- nomed wounds, in which accidents the des- truction of the poison always :ormed a prin- cipal indication in the treatment. — Wounds, accompanied with considerable inflamma- tion, were not deemed proper tor the use of sutures, as the stitches had a tendency to in- crease the inflammatory symptoms. Also, as contused wounds necessarily suppurated, and, consequently, could not be united, su- tures were not recommended for them ; nor were they judged expedient for wounds at- tended with such a loss of substance as pre- vented their lips from being placed in con- tact. Formerly, wounds penetrating the chest, were not united by sutures ; nor were those in which large blood-vessels were in- jured ; at least, until all danger of hemor- rhage was obviated by the vessels being tied. Dionisbelieved, with several otherautliors, that wounds should not he united, when bones were exposed, on account of the ex- foliations which might he expected, '.rids precept is no longer valid ; lor when bones are neither altered nor diseased, and are only simply denuded, or divided with a cut- ting instrument, no exfoliations will com- monly follow, if the surgeon take care to replace the fresh-cut soft parts so as to cover the exposed portion of the bone. The practicable ness of uniting wounds, attended with the division of a bone, is confirmed by numerous facts. De la Peyronie com- municated to the French Academy of Sur- gery, a case conclusive on this point. A man was wounded with a cutting instru- ment, in an oblique direction, on the exter- nal and middle part of the arm. The bone was completely cut through, together with the integuments and muscles, in such a manner that the arm only hung by an un- divided pox’tion of the skin, about an inch wide, under which were the large vessels. De la Peyronie tried to unite the parts, be- ing convinced that it would be time* enough to amputate afterward, if the case should require it. He placed the two extremities of the divided bone in their natural situa- tion ; made several sutures for promo- ting the union of the soft parts, and ap- plied a bandage to the fracture. In this ban- dage there were slits, or apertures, over the wound, to allow the dressings to be applied. Spirit of wine, containing a little muriate of ammonia, was used as a topical application, and the forearm and hand, which were cold, livid, and insensible, were also fomented with the same. By these means the natural warmth was restored, and the wound was dressed in a week the dressings were re- moved, through the opening in the bandage ; in a fortnight they were changed a second time, and the wound seemed disposed to heal. On the eighteenth day, the healing had made considerable progress ; the part had a natural appearance ; and the beating of the pulse was very perceptible. De la Peyronie now substituted a common roller for the preceding bandage, and care was ta- ken to change the dressings every ten days. In about seven weeks all applications were, left off, and at the end of two months the patient was quite well, with the exception of a little numbness in the part. This case is one of the most important in all the records of surgery , for it displays, in a most stri- king manner, what very had wounds it is the duty of the surgeon to attempt to unite ; and above all, it exemplifies the propriety of attempting to save many compound frac tures, which, judged of only from first ap- pearances, would lead almost any one to resort to amputation. In such cases, when the divided parts are put in contact, the ap pearances are quite altered. From what has been already stated, it ap- pears that surgeons, a considerable time back, did not at once sew up every sort of wound ; though the considerations, which led them not to close the wound, were erroneous, as may, perhaps, he said with re- spect to the apprehension of bleeding and exfoliations. The best modern practitioners employ sutures much less frequently than SUTi Ikeir predecessors. Pibrac ? s dissertation on the abuse of sutures, inserted in the third volume of the Memoirs of the Academy of Surgery, has had considerable effect in pro- ducing this change, and I may safely add, this improvement in practice. This judi- cious and enlightened practitioner opposed the method of uniting wounds by means of sutures, which, he contended, ought never to be adopted in practice, except in certain cases in which it vsas absolutely impossible to keep the sides of the wound in contact, by means of a suitable posture, and the aid of a methodical bandage. Such circum- stances Pibrac represents as exceedingly rare, if they ever occur at all. He speaks of sutures as seldom fulfilling the intention of the surgeon, who, in the majority of cases in which he employs them, finds himself ne- cessitated to remove them, before they have accomplished the wished-for end. Pibrac believes that sutures are generally more hurtful than conducive to the union of wounds ; and that when they succeed, they do not effect a cure more speedily than apro- per bandage. He cites numerous cases of very extensive wounds of the abdomen, neck, fee. for the cure of which a bandage proved effectual, and this even in many in- stances in which sutures had previously failed, and cut their way through the flesh. Louis, who adopted the opinions of Pibrac, published in the fourth volume of Mem. de V Acad de Chirurgie, a valuable dissertation, in which he endeavours to provd; that even the harelip can be better united, by means of the uniting bandage than sutures ; a case, however, which the best modern surgeons very rightly agree to consider, for particular reasons elsewhere noticed, (see Harelip ,) as an example, in which a suture is adviseable. As far as 1 can judge, the fair statement of the matter is, that sutures are by no means requisite in the generality of wounds; but that there are particular cases, in which either their greater convenience, or superior efficacy, still makes them approved, and employed by all the most eminent practi- tioners of the present day. Since sutures cannot be practised, without additional wounds being made, and pain occasioned, and since the threads always act as extrane- ous bodies in the parts, exciting more or less inflammation and suppuration round them ; there can be no doubt that their employ- ment is invariably wrong, whenever the sides of a wound can be maintained in con- tact by less irritating means, with equal steadiness and security. For, what is it which generally counteracts the wishes of the surgeon, and renders his attempts to make the opposite surfaces of wounds grow together unavailing? Is not the general cause too high a degree of inflammation, which necessarily ends in suppuration ? Are not sutures likely to augment inflammation, both by the additional wounds of the needles, and the still more pernicious irritation of the threads which always act as foreign bodies, sometimes producing not merely an increase "f inflammation and suppuration in their voL.n 58 JilES. 4*7 track ; but frequently such ulceration as en- ables them to cut their way out, or else sloughing of the parts ; or, in particular con- stitutions, a very extensive erysipelatous redness. In consequence of the ulcerative process, sutures very often cease to have the power of any longer keeping the edges of wounds in contact ; as the observations of Pibrac, and, indeed, what every man may daily remark in practice, fully testify ; and the violent inflammaiory symptoms which are excited, frequently oblige the surgeon to cut the threads, and withdraw them altogether. But, even admitting, that by the general adoption of sutures some wounds would be united, which could not be so were this means of accomplishing the union aban- doned, still it must be allowed, on the other hand, that the cause of some wounds not uniting is entirely ascribable to the irritation occasioned by the sutures themselves. Hence, if it be only computed, that as many wounds are prevented from uniting by the irritation of sutures, as other wounds which are united by their means, and could be united by no other methods, we must still perceive, that mankind would be no sufferers, and surgery undergo no deterioration, were sutures alto- gether rejected from practice. 1 believe, however, that every man, who has had op- portunities of observation, and has made use of them with an unprejudiced mind, will feel persuaded that more wounds are hin- dered from uniting by sutures, than such as are healed by them, and could not be united by other means. But prudent practitioners are not obliged, either to condemn or praise the use of su- tures, in every instance, without exception Men of independent principles will always adopt the line of conduct which truth points out to them as that which is right ; nor will they obstinately join Pibrac and Louis, in contending that sutures are always improper and disadvantageous, nor with other bigoted persons, who may use sutures in every kind of wound whatever. Perhaps, sutures arc still rather too much employed, and, in all probability, will long be so. It will be difficult entirely to eradicate the prejudices, ou which their too frequent use is founded, as long as, what may be called, the teachers of surgery are seen holding up the practice for imitation in every principal hospital in the kingdom. Such surgeons, however, as are ready to imbibe fair and candid senti ments on the subject, and to qualify them - selves for practising this part of surgery with judgment, should by no means neglect to read both what Pibrac and Louis have writ- ten on the subject. I know that the latter authors are a little too sanguine in their re- presentations ; but, as I have already re- marked, sutures are still rather too much used, and something is yet necessary to do away a certain unwarranted habit of having recourse to them without real necessity. Nothing will tend to produce this desirable change so much, as the perusal of every ar- gument against their employment. T BANDAGE m I am decidedly of opinion, not from what I have read, but what 1 have actually seen, that the sides of the generality G f wounds are capable of being effectually kept in con- tact, by means of a proper position of the part, and the aid of strips of adhesive plaster, compresses, and a bandage. I believe that such success can be obtained with every ad- vantage which can be urged in favour of sutures, and without their disadvantages ; such as greater pain, inflammation, &x I even think, with Louis, that the harelip might in general be united very well by means of a bandage ; but still I am of opi- nion, that the twisted suture is attended with least trouble, is most suited for universal practice, and that, unless such pains were taken as many practitioners would not, and others could never take, the method by ban- dage would frequently fail. I find it exceedingly difficult to lay down any fixed principles for the guidance of the surgeon, in respect to when he ought, and when he ought not, to use sutures. Perhaps, sutures should be made use of for all cuts and wounds, which occur in parts which are subject to an unusual degree of motion, such as would be apt to derange the operation of bandages, sticking plaster, and compresses. Hence the propriety of using the twisted suture for the harelip. Sutures are probably, for the most part, advantageous in all wounds of the abdomen, of a certain length, and attended with ha- zard of the viscera making a protrusion. In this situation, the continual motion and ac- tion of the abdominal muscles, in respiration, besides the tendency of the viscera to pro- trude, may be a reason in favour of the use of sutures. When tw'o fresh-cut surfaces positively cannot be brought into contact by sticking plaster, bandages, the observance of a pro- per posture, &e. there can be no doubt of the advantage of using sutures, if they will answer the purpose. Some wounds of the trachea ; some wounds made for the cure of certain fistulous communications between the vagina and bladder, or others for the cure of similar affections in the perinaeum, afford instances of cases to which I allude. 1 observe, that many surgeons in this me- tropolis use sutures for bringing the sides of the wound together alter several operations ; as that of removing a diseased breast, castra- tion, and operations for strangulated hernia. The reason for using sutures in the scro- tum, I suppose, arises from the difficulty of keeping the edges of the wound in contact, owing to the great quantity and looseness of the part. In this case, I cannot deter- mine whether sutures are really necessary or not ; but, alter the amputation of the breast, I have no hesitation in pronouncing their employment wrong and injudicious. I shall conclude with referring to what PL brae and Louis have written on the above subjects, in Mini. de l’ Acad, de Chir. Tom. 3 and 4, Sharp, Dionis , Gooch , Le Dran , Btr trandi , Sabatier B . Beil , and J. Bell , have all treated of sutures. See also C. E. Boeder 3 Sutures Vulnerum ; Upsnl , 1772. SYMPA THETIC BUBO. See Bubo. SY ACHYSIS. (from a-vyyyu*. to confound.;' The term synchysis sometimes denotes the confusion of the humours of the eye occa- sioned by blows, and attended with a rup- ture of the internal membranes and capsules Beer understands by the expression, a dissolution of the vitreous humour, or the state of it in which its consistence is en - tirely destroyed. (See Lthre von den An - genkr. B. 2, p. 257.) SYNECHIA. The case in which the iris adheres to the cornea is termed synechia anterior; that in which the uvea adheres to the capsule of the lens, synechia posterior.. Beer has delivered two valuable chapters on these subjects. The synechia posterior, on account of the frequent delicacy of the adhesions, is apt not to be detected unless the eye be examined with particular care. A magnifying glass should be used, and the pupil be first dilated with hyoscia- mus, or belladonna. The treatment, as far as the prevention and removal of such ad- hesions are practicable, strictly belongs to the subject of iritis. (See Ophthalmy.) With the view of dispersing them, Beer praises the good effects of applying to the eye itself ointments containing preparations of mer- cury, or a collyrium hydrarg. oxymuriatis, to which some of the thebaic tincture is added. As an inward medicine, he says, calomel is the most effectual. When eye-salves are used. Beer recommends a little of the extract of hyosciamus to be mixed with them, so that they may dilate the pupil, and thus suddenly break any slight threads of lymph. ( B . 2, p. 58.) For additional information on the synechia pos- terior and anterior, see Lehre von den Au~ genkr. B. 2, p. 54 and p. 263. Also Beger t De Synechia seu prelernaturali adhesione cor - nnc cum iride. Haller , Disp. Chir. T. 1, p. 435. SYNTHESIS, (from e, no one will suppose that it, or any other form of lues venerea, is capable of ■161 changing into a true scirrhous or cancerous disease. Perhaps, therefore, it might be more consistent and advantageous to restrict the appellation of sarcocele, to an indolent fleshy enlargement of the testicle, unac- companied with any present symptoms of malignancy, or any marks of its being the effect of a specific disease ; and as soon as the case evincesanothercharacter, the name should correspond with the particular nature of the disease. We need not here enter into a minute ac- count of the various sarcomatous diseases, to which the testicle is subject ; for, they have no peculiarity in them, except what depends upon their situation,, and the gene- ral characters of the different species of sar- coma will be considered in a future article. (•See Tumour.) -The testicle is especially liable to three kinds of sarcoma, which have been named, by Mr. Abernethy, the common vascular, the cystic , and the medullary. The latter case, however, which is often called soft cancer of the testicle, I shall describe in the present article, in order that the reader may judge whether there is any material difference between this case and another distemper to which the testicle is subject, (See Fungus Hcematodes.) Sometimes the testicle is converted into a truly scrofulous mass. It is increased in size, and when cut into, a whitish, or yellowish coagulated matter is discovered, mixed with pus. The complaint is not attended with so much pain and induration as a scirrhous disorder of the testicle ; nor does it produce any un - favourable state of the health. As Dr. Buillie observes, the testicle is of- ten found converted into a hard mass, of a brownish colour, and generally intersected with membranes. Sometimes, there are cells in the tumour, which are filled with a sanious fluid. ( Morbid Anatomy , <^c. p. 352, 353, Edit. 2.) This is the truly scirrhous its tide which is attended with great hardness, severe pains darting along the spermatic chord to the loins, and an unequal knotty feel. In general the health becomes impair ed To use Mr. Pott’s words, sometimes the fury of the disease brooks no restraint : but, making its way through a!! the mem branes, which envelope the testicle, it either produces a large, foul, stinking, phagedenic ulcer, with hard edges, or it thrusts forth a painful gleeting fungus, subject to frequent hemorrhage. (Pott's Chimrgical Works , Vol. 2, p. 390, Edit. 1808.) These latter states of the disease are denominated cancer of the testicle. Sooner or later, the scirrhous induration extends from the epididymis upward along the spermatic chord, even within the abdo- minal ring. In the latter circumstance, the lymphatic glands in the groin usually be- come diseased ; and this extension of mis chief, together with the impossibility of re- moving the whole of the diseased chord, too frequently deprives *the patient of every chance of getting well. I have already stated, that some of the most simple sarcomatous enlargements of TESTICLE. 462 the testicle are capable of assuming, in a very sudden manner, a malignant and can- cerous tendency ; and that sometimes the scirrhous induration of the chord makes a rapid progress upward. Hence, that sur- geon acts with prudence, who recommends the early extirpation of every, testicle, which is incurably diseased, and so deprived of its original organization, as to be totally unfit for the secretion of the semen. Chronic enlargements of the testicle are sometimes attended with an accumulation of limpid fluid in the tunica vaginalis, and the disease is then termed , hydro arcocele, an ap- pellation first employed by Fabricius ab Aquapendente. The hardness and swelling of the epididy- mis, remaining after an acuie inflammation of the testicle (see Hernia Humaraii •>,) do not Constitute a complaint, which surgical authors class with sarcocele ; for, the dis- ease hardly ever, increases so as to give trouble. I have stated, that sarcoceles, in common with the generality of other sarcomatous tu- mours, may change into dis, tempers, which, in point of malignity, and the manner in which they injure the health, are quite as bad as cancer itself, ft is said, however, that sarcocele of the epididymis rarely be- comes malignant, and is much more easy of cure, than the same disease of the glan- dular portion of the testicle ; but both parts are often diseased together. Sarcoceles sometimes continue for years, without undergoing any particular change ; in other instances, they increase with sur- prising rapidity. t he inconveniences, which they excite, often proceed chiefly from their weight and magnitude : their weight occa- sions an uneasy, and even a painful sensa- tion in the loins, especially when the pa- tient neglects to wear a suspensory bandage, or a bag truss for the support of the part. The danger of a sarcocele arises from the increase and extension of the hardness up the spermatic chord, and from the change of the tumour from its indolent state into a painful, ulcerated, and incurable disease. A sarcocele sometimes 1 'bears a resemblance to hydrocele of the tunica vaginalis. It sometimes has the usual pyramidal shape of the latter disease, and, like it, is always situated at the lower end of the spermatic chord. The chief difference between the two cases seems to be, that the sarcocele is bard, while the hydrocele has a soft, yield- ing, elastic feel. It should be known, how- ever, that the fungus haematodes of the tes- ticle is remarkable for the deceitful feel of fluctuation and elasticity, which it presents ; and every surgeon ought to be aware, that a sarcocele is not always particularly hard, and that hydroceles are sometimes exceed ingly indurated. The sarcocele, indeed, is not transparent; neither is the hydrocele in certain instances ; and, .these are cases, in which a mistake may easily be made. Still, with due attention, both diseases may be discriminated with tolerable precision, the sarcocele, when held in the surgeon’s hand, seems heavier than the hydrocele. Every part of a diseased te ticle is seldom equally indurated, so that the sarcocele is usually much softer in some places than others. The hydrocele presents the same kind of feel at every point, except behind, where the testicle is felt. When, in the case of hydrocele, pressure is made in this latter situation, the patient experiences a much more acute sensation, than when the pres- sure is made upon any other part of the tu- mour ; but, in the example of sarcocele, the patient commonly has the same kind of feel let the pressure be applied to any part of the -.welling whatsoever. When the up- per portion of the spermatic chord can be fell, and it seems quite hard and thickened, the surgeon has reason for suspecting the case to be a sarcocele. Lastly, though a hydrocele, w r hen gently handled, may seem very hard, yet, on being more strongly com- pressed, it will generally betray a soft, elas- tic feel, which, excepting instances of fungus haematodes, is never the case with an indu- rated sarcocele. It has been already explained, that a sar- cocele is sometimes conjoined with a hy- drocele, which case is well known among surgeons by tbe appellation of hydro-sarco - cele. As the diseased testicle is then sur- rounded with fluid, it cannot be felt and examined by the fingers. However, when an unusual degree of hardness is percepti- ble at the back part of the tumour, where the testicle is situated, or when the upper portion of the spermatic chord is found to be quite indurated, there is reason for sus- pecting that the testicle is diseased. The sarcocele also is commonly the original and principal complaint, the hydrocele not oc- curring till some time after the enlargement of the testicle. In some unusual cases, the substance of the scrotum is converted into an indurated mass, which occasionally attains a vast size, and presents the appearance of an enormous sarcocele. An example in which the tu- mour weighed 701b. has been lately publish- ed by Dr. Titley (See . Med. Chir Trans . Vol. 6, p. 73.) In one case, recorded by Dr. Cheston, a swelling of this kind was as large as a child’s head. On dissection of the parts, the testicle and tunica vaginalis were found to be quite free from disease. The tumour proceeded entirely from an indura- tion of the cellular membrarfe, which im- mediately covers the external surface of the vaginal coat. This curious disease is more common in warm climates, and seve- ral instances of it were met with in Egypt by Baron Larrev. (See Mem. de Chir. Mili- laire, T. 2, p. 1 10, et serp) Some interesting particulars relative to it will be found in another part of thte Dictionary. (See Scro- tum.) The operation of castration -is the most certain means of relieving the patient from sarcocele. This measure, however, is not invariably practicable, nor is it always ne- cessary ; for, sometimes the induration of the testicle admits of being dispersed by the TESTICLE. judicious employment ot internal medicines and external applications. The hope of ac- complishing this desirable object may De reasonably entertained, when the swelling is not very large, when it has not existed a considerable time, and when it is not at- tended w ith very great induration Expe- rience has proved, that some kinds of s-tr- cocele have yielded to the exhibition of emetics, ( Warner, Pringle, and Home i?i Chymical Experiments ;) to a decoction ot ono .isspinos. ( Bergius Mai. Med. Richter's Chir. Bibl. 7 B. p 6U5 ;) to cicuta and bark (Warner ;) to mercurial frictions {Le bran- B. Bell, Richer and, Detpech ; to the external use of the liquor amnion, acetatis (Rich er's Chir. Bibl. B.p. 127 ;) to poultices contain- ing opium (Fothergill, in Med. Obs.ty Inq. Vol. 5 ;) to a lotion made of a strong de- coction of hemlock ( Warner ,') to the steam of vinegar, the repeated employment of leeches, and the ap lication of cold, foe. The operation of all these means w ill be ad- vantageously assisted by the continual use of a bag-truss, the observance as much as possible of an horizontal position, and attention to a suitable low diet. "Mr. Pott believed that the man who has the misfortune to be afflicted with a sarco- cele, has very little chance of getting rid of the disease by any plan except extirpa- tion ; and all the time the operation is de- ferred, he carries about him a part, not only useless but burdensome, and which is every day liable to become worse, and unfit for such an operation. JNow, although there is a great deal of truth in this opinion, yet, I conceive, it is rather exaggerated, and that it would tend to authorize the practice f castration to an extent beyond all necessity. I certainly think, with Mr. Pott, tha : there never was a sarcocele cured, w here the or- ganization of the testicle had been destroy- ed by disease, or where its structure had suffered so much as to render it incapable of the office for w hich it is destined. But such state cannot always be known by m spection or manual examination, and were a surgeon to condemn to the knife every testicle which he finds affected with indo- lent swelling and induration, he w r ould re- move many wdiich, under some of the^above plans of treatment, might, be perfectly cu- red. That there are some chronic enlarge- ments ot the testicle which may be resolved, is a truth of which experience must have convinced the generality of surgeons. The scrofulous induration, and several other swellings of this organ, which are very imperfectly understood, may some times be benefited, and even entirely cured, just like some analogous affections of the breast. What is termed the venereal sarco cele (Mr. Pott allows) always gives way to a mercurial course properly conducted. The diagnosis of this case, it must be con- fessed, is not very clearly explained by sur- gical w riters, nor w r as its reality acknow- ledged by Mr. blunter. According to Mr. Pott, it is seldom an early symptom, and he does not remember ever to have seen 403 an instance in wdiich it was not either im mediately preceded, or accompanied by some other appearances plainly venereal. He adds, that it has neither the inequality nor darting paii s of scirrhus. But the question, whether the case is truly syphilitic or not, is lar less interesting than the ques- tion, whether there are not many sarcoceles which may be diminished and cured by mercury P The affirmative cannot be ques- tioind. I have seen many such cases my- self, and there are numerous examples on record. v statement of several has been lately published by Richerand. (See A r oso - graphic Chirurgicale, T. 4, p. 300, et seq. Edit. 4.) The authority of Delpech is also on the same side. Precis Element air e dcs Maladies Reputees , Chir T. 3 ,p. 564.) Indeed this last writer maintains, that many common sarcoceles and scirrhi of the'esticle are so much alike in their symp- toms. that the difference of their nature cannot always be at once detected by the practitioner. Hence, although I am an advocate tor the early performance of cas- tration in cases of sarcocele, w here there is reason to suppose the disease so far advan - ced, that the organization of the testicle is totally destroyed; or where internal and external remedies have been tried a certain time in vain ; yet these sentiments do not incline me to recommend the operation for other examples in which the disease is quite recent, and no plan of treatment what- soever has been fairly tried, i have already enumerated various plans of treatment, which have been proved by experience to be sometimes capable of affording relief. The disease of the testicle, which is usually called the scrofulous sarcocele, like other forms of scrofula, often gets well spontane- ously after a certain time, and it may fre - quently be considerably benefited by admi- nistering internally the conium maculatum, and small doses of the submuriate of mer- cury ; lotions of sea-water, or poultices of sea-w eetis, being applied to tne scrotum. Several other indolent enlargements of the testicle yield to frictions with ca . phorated mercurial ointment on the scrotum. The late Mr. Ramsden thought that some sarco- celes might be relieved by removing with bougies a supposed morbid irritability of the urethra, with which bis theories led him to connect the origin of the complaint. (See Pracl. Obs. on Sdemceie, fyc.) The novelty of this suggestion for a time attracted con- siderable notice ; but the interest which it once excited has now died away; a suffi- cient proof to my mind, that the practice inculcated was not of much value. From the preceding observations, it may be inferred, that all chronic enlargements of the testicles are not incurable ; but that w e ought at the same time to be duly im- pressed with the expediency of not wasting too much time in the trial of means which are not (6 be depended upon, and which if continued immoderately long, might allow the disease to advance too far to be capable of beipg afterward effectually extiv TESTICLE. 464 pated. According to Mr. Foil, the circum- stances in which the operation of castration is adviseable, or not, are of two kinds, and relate either to the general habit of the pa- tient, and the disorders and indispositions of some of the viscera, or to the state of the testicle and spermatic chord A pale, sallow complexion, in those who used to look otherwise ; a wan counte- nance, and loss of appetite and ilesh, with- out any acute disorder ; a fever of the hec- tic kind; and frequent pain in the back and bowels are, in those who are afflicted with a scirrhous testicle, such circumstances as would induce a suspicion of some latent mischief in some of the viscera; in which case, as Mr. Fott truly observes, success from the mere removal of the testicle is not to be expected. They whose constitutions are spoiled by intemperance, previous to their being attacked with this disease; who have hard livers, arid anasarcous limbs; be says, are not proper subjects for such an operation. Hard tumours within the abdo- men, in the regions of the liver, spleen, kidneys, or mesentery, implying a diseased state of the said viscera, are very material objections to the removal of the local evil in the scrotum, in short, whenever there are manifest appearances, or symptoms of a truly diseased state of any of the principal viscera, the success of the operation be- comes very doubtful. “ The state of the mere testis can hardly ever be any objection to the operation ; the sole consideration is the spermatic chord : if this be in a natural state, and free from disease, the operation not only may, but. ought to be performed, let the condition of the testicle be what it may ; if the sperma- tic chord be really diseased, the operation ought not to be attempted. And Mr. Pott afterward remarks, “ when the spermatic vessels are not only turgid and full, but firm and hard; when the membrane which in- vests and connects them has lost its natural softness and cellular texture, and has con- tracted such a state, and such adhesions as not only greatly to exceed its natural size, but to become unequal, knotty, and painful, upon being handled, and this state has possessed all that part of the chord which is between the opening in the oblique muscle and the testicle, no prudent, judi- cious, or humane man, will attempt the operation; because he will, most certainly, not only do no good to his patient, but will bring on such symptoms as w ill most ra- pidly, as well as painfully destroy him.” “ On the other hand,” says Pott, “ every enlargement of the spermatic chord is not of this kind, nor by any means sufficient to prohibit or prevent the operation. “These alterations or enlargements arise from two causes, viz. a varicose dilatation of the spermatic vein, and a collection, or collections, of fluid in the membrane in- vesting and enveloping the said vessels.” Shortly afterward the same practical writer continues: — “ The diseased state of a truly r-cirrhous testicle, its weight, and the altera- tion that must be made in the due and pro- per circulation of the blood, through both it and the vessels from which it is depend- ent, may and do concur in inducing a vari- cose dilatation of the spermatic vein, with- out producing that knotty, morbid altera- tion and hardness, which forbid our at- tempts. Between these, a judicious and experienced examiner will generally be able to distinguish. “ In the former, (the truly diseased state) the chord is not only enlarged, but feels unequally hard and knotty ; the parts of which it is composed are undistinguishably blended together; it is either immediately painful to the -touch, or becomes so soon after being examined ; the patient com- plains of frequent pains shooting up through his groin into his back ; and from the dis- eased state of the membrane composing the tunica communis, such adhesions and connexions are sometimes contracted, as either fix the process in the groin, or render it difficult to get the finger and thumb quite round it. “ In the other (the mere-varicose disten- tion) the vessels, though considerably en- larged and dilated, are nevertheless smooth, soft, and compressible ; the whole process is loose and free, and will easily permit the fingers of an examiner to go quite round it, and to distinguish the parts of w r hich it is composed ; it is not painful to the touch ; nor does the examination of it produce or occasion those darting pains which almost always attend handling a process malig- nantly indurated.” Mr. Pott next explains that, “ in the cellular membrane, leading to a diseased testicle, it is no very uncommon thing to find collectionsof extravasated fluid. These, as they add considerably to the bulk and apparent size of the process, make the com plaint appear more terrible; and, as I have just said, less likely to admit relief. “ When the extravasation is general, through all the cells of the investing mem- brane. and the spermatic vessels themselves are hardened, knotty, and diseased, the case is without remedy ; for, although a puncture, or an incision, will undoubtedly give discharge to some, or even the greatest, part of the fluid; yet this extravasation is so small and so insignificant a circumstance of the disease, and the parts, in this state, are so little capable of bearing irritation, that an attempt of this kind must be inef- fectual, and may prove mischievous. “But, on /the other hand, collections of water are sometimes made in the same membrane, from an obstruction to the pro- per circulation through the numerous lym- phatics in the spermatic process, while the vessels themselves are really not diseased, and therefore very capable of permitting the operation. In this case, the fluid is generally in one cyst, or bag, like to an encysted hydrocele, and the spermatic chord, cyst and all, are easily moveable from side to side ; contrary to the preceding ,state in which the general lead in the membrane TESTICLE. 465 fixes the whole process, and renders it almost in moveable. “ A discharge of the fluid will, in this case, enable the operator to examine the true state of the process, and, as I have t wice or thrice seen, put it into his power to free his patient from one of the most terri- ble calamities which can befall a man.” (See Pott on Hydrocele, tyc.) The testicle is subject to a disease often called soft cancer , which, though of a very malignant and incurable nature, is different from the true cancer, already de- scribed. It has been particularly noticed by Mr. Abernethy. under the name of Me- dullary Sarcoma. In most of the instances which this gentleman has seen, the tumour, when examined after removal, appeared to be of a whitish colour, resembling on a general and distant inspection, the appear- ance of the brain, and having a pulpy con- sistence. He has also often seen it of a brownish red appearance. The following case is related, to illustrate the nature and progress of the disease. “ A tall, thin, healthy-looking man, of about forty years of age, had, about fifteen years before, a swelled testicle from a go- norrhoea ; the epididymis remained indura- ted. Six years afterward it became enlar- ged, and a hydrocele at the same time formed. Half a pint of water vvas dischar- ged by a puncture, but inflammation suc- ceeded the operation, and this testis became very large. An abscess formed, and burst in the front of the scrotum, and the testis subsided in some degree. Mercury was employed to reduce it, but without effect. The part, however, was indolent, and gave the patient no trouble but from its bulk. “ About a year afterward, a gland enlar- ged in the left groin, (ihe same side as the testis.) another then became swoln in the right groin, and in the course of two years, several, glands in each groin had attained a very considerable magnitude. At this peri- od, he was admitted into St. Bartholoon w’s Hospital, under the care of Mr. Long. j.he testis was, at this time, between four and five inches in length, and about three in breadth: it resembled its natural foim, and wa- indolent in its disposition. The spermatic chord was thickened, but not much indurated. Four or five glands were enlarged in the groin on both sides ; each of which was of the size of a very large orange ; and when observed together, they formed a tumour of very uncommon shape and magnitude. “ They gradually increased in size for several months, till at last the skin appeared as if unable to contain them any longer. It became thin, inflamed, and ulcerated, Tlrst in the left groin, and thus exposed one of the most prominent tumours. The exposed tumour inflamed and sloughed progressive- ly, till it entirely came away. As the sloughing exposed its vessels, which were large, they bled profusely, insomuch that the students endeavoured, but in vain, to secure them by ligatures : for the substance Pox> IF, 59 of the tumour was cut through, and tom away in the attempt. Pressure by the fin- ger, eoniinued for some time, was the only effectual mode of restraining this hemor- rhage. “ The loss of one gland relieved the dis- tended skin, which had only ulcerated on the most prominent part of the tumour, and had not become diseased. It now lost its inflamed aspect: granulations formed, and a cicatrix took place. In the opposite groin a similar occurrence happened. One gland, exposed by the ulceration of the skin, slough- ed out, being attended by the circumstances just recited. However, htTorethe skin was cicatrized, ulceration had agaUntken place in the right groin, in conseqlwice of the great distention of the skin from the growth of the tumour; and sloughing had begun in the tumour, when the patient, whose vital powers had long been greatly exhausted, died.” (See Mlrnethys Surgical Observa- tions, 8fc°. 1S04.) The preceding kind of disease is now ge- nerally considered to be fungus haematodes If there are any differences, they consist in the parts sloughing out, and then healing, instead of a fungus shooting out, and con- tinually increasing in size. (See Fungus Haematodes.) JDi. Bail lie has noticed some affections, in. which the testicle becomes bony, cartilagin ous, &o. ; but on these it is not necessary for us to dwell in this Dictiouary. The preceding observations may be considered as relating expressly to the diseases for which castration is generally pertormed. (See Cas- tration.) Besides the fungus, which arises from the testicle in the advanced stage of carcinoma, arid the bieeding fungous growth, which arises from tliis organ in the ulcerated state of fungus hajmatodes, there is another su perficial fungous excrescence, to which the testicle is subject, and which is entirely free from all malignancy. The disease to which I refer, has been noticed by Callisen, under the name of lipoma of the testicle. “ Si ex superlicie albugineas vel ipsa tunica vaginali excrescentiae surgunt, totum demum testem involventes, et scirrhum seu fungum, men- tientes, ipsius tamen testis substantia parum aut vix de statu naturali aberrante ; malum naturam lipomatis sequitur, vix unquamm scirrhum et carcinoma abiens.” (See Sys- tema Chirurgice Hodi&rnce , Vol. 2, p. 145, Edit. i800.) The superficial fungus, or lipo- ma of the testicle, was noticed in an early edition of another publication, and described as “ a particular affection of the testicle, iii which a fungus grow's from the glandular substance of this body, and in some instances, from the surface of the tuniea albuginea. This excrescence is usually preceded by^tu enlargement of the testicle, in consequence of a bruise, or some species of external vio- lence, A small abscess takes place and bursts, and from the ulcerated opening the fungus gradually protrudes.” I then proceed- ed to represent how unnecessary and impro- per it was to extirpate the testicle, on account* 1ES 'i'ET 406 of this affection, if after the subsidence of tiie inflammation, the part should not seem much enlarged and indurated. I recom- mended the fungus to be cut off, or else de- stroyed with caustic; and 1 founded my ad- vice on a successful attempt of the first kind, which was made in St. Bartholomew’s H os- pital, by Sir Janies Earle, a little while before my book was published. (See First Lines of the Practice of Surgery , p. 399.) An interesting little paper has also been written on the subject, by my friend Mr. Lawrence, who has favoured the public with a more particular account, and nine cases iliustrativigtf the causes, symptoms, and progress tlWe disorder. According to Mr. Lawrence, the patient generally assigns some blow’, or other injury, as the cause of the complaint ; in other instances, it originates in consequence of the hernia humoralis from gonorrluea, and sometimes appears spontaneously. A painful swelling of the gland, particularly characterized by its hard- ness, is the first appearance of the disease. After a certain length of time, the scrotum, growing gradually thinner, ulcerates; but the opening which is thus formed, instead of discharging matter, gives issue to a firm, and generally insensible fungus. The surround- ing integuments and cellular substance are thickened and indurated by the complaint, so that there appears to be altogether a con- siderable mass of disease. The pain abates, and the swelling subsides considerably, when t he scrotum has given way. In this state, the disorder appears very indolent ; hut if the fungus be destroyed by any means, the integuments come together, and a cicatrix ensues, which is inseparably connected with the testicle. Mr. Law rence next informs us, that if the part be examined while the fun- gus si ill remains, the excrescence is found to have its origin in the glandular substance of the testicle itself ; that the coats of the part are destroyed to a certain exteut ; and that a protrusion of the tubuli seminiferi takes place through the aperture thus formed. Mr. Lawrence says, he has often ascertained the continuity of the excrescences with the pulpy substance of the testicle, of which more or less remains, according to the differ- ence in the period of the disorder. The same gentleman thinks, that the glandular part ot the testicle experiences an inflamma- tory affection in the first instance, in conse- quence of the violence inflicted on it ; and that the confinement of the swollen sub- stance, by the dense and unyielding tunica albuginea, sufficiently explains the peculiar hardness of the tumour, and the pain w hich is always attendant on this stage of the dis- order. The absorption of the coats of the toslis, and of the scrotum, obviates the ten- sion of the parts, and (hereby restores ease to the patient, at the same time that the fungus makes its appearance externally. With regard to the, treatment, Mr. Law- rence is of opinion, that if thecomplaint were entirely left to itself, the swelling would pro- !' bably subside, the fungus shrink, and a com- plete cure ensue, without any professional assistance ; but lie adds, that the disorder is so indolent in this stage, that a spontaneous cure would not be accomplished till after much time. He says that the excrescence may be removed wiih a knife, or if the na- ture of its attachment permit, with a ligature, or that it may be destroyed with escbarotic applications. Mr Lawrence very judicious- ly gives die preference to removing the tumour to a level with the scrotum, by means of the knife, as the most expeditious and ef- fectual mode of treatment. He can discern no ground whatever for proposing castration in this malady, since in no part of its progress, nor in any of its possible consequences and effects, can it expose the patient to the slight- est risk. Mr. Lawrence also mentions the possibili- ty of there being other kinds of tungi, which may be met with, growing from the testicle, and quotes an distance, in which Dr. Ma cartney found a fungus, of a firm and dense Structure, growing from the tunica albugi- nea, while all the substance of the testicle it self was sound. Dr. Macartney was so kind as to show me the preparation, affording a clear specimen of the second kind of fungus. The cases drawn up by Mr. Lawrence are^ in my opinion, highly interesting, and may be read in The Edinb. Med. and Surg. Jour nal,for July , 1808. I have already noticed, that Cailisen repre seats the lipoma, as sometimes originating from the surface of the tunica vaginalis, a kind of case which has not yei fallen under my observation. In the preface to the last edition of this Dietionai y, p. 10, I quoted a case, published by Dr. H. Weinhold, in which the operation for bubonocele was performed, and^is the testicle w T as diseased, the surgeon ftade a complete division of (he spermatic chord, tied the spermatic arteries, and then left the tes- ticle in its natural situation. After a time, the absorbents had diminished the part to a very inconsiderable little tumour. (See Journ. der Pracl. Heilkunde von C. IV. Hufe- land and K. Himly , 1812, Zehntes, Stack, p. 112.) This case merits attention, and ought to have been cited in the article Cas- tration, because it is the first instance, l be- lieve, m which such practice was tried Subsequently, the following work has been published, (hough I have not yet met with it. u JYouvelle Methode de trailer le Sarcocele. sans avoir rccours a V extirpation du Testicule , par C. Th. Maunoir , 8i>o. Geneve, 1820 The new plan consists in dividing and tying the spermatic arteries, and leaving the rest of the chord and the testis undis- turbed. TETANUS. (from , to stretch.) Tetanus is defined by all authors to be a more or less violent, and extensive controc tipn of the muscles of voluntary motion, at- tended with tension and rigidity of the parts affected. The excessive contraction of the muscles is kept up without any intervals of complete relaxation, in which respect the disorder dif- fers from ordinary spasms and convulsions. TETANUS'. 467 where the contractions and relaxations alter- nate in rapid succession. In tetanus, the powers of sensation and intellect also re- main unimpaired, in which particularity it forms a contrast to epilepsy. ( Rees's Cyclo- pedia, art. Tetanus.) When its effects are confined to the mus- cles of the jaw or throat, it is called trismus or locked jaw ; when all the body is affected and becomes rigid, but retains its ordinary straightness, the case is named tetanus. When the body is bent forwards, the di-ease is termed emprosihotonos : and opisthotonos , when the muscles of the back are principally affected. To these four forms, some writers have added a fifih, which they denominate pltu- rosthotonos, and w hich is characterized by the body being drawn to one side. It is the tetanus lateralis of Sauvages. The different terms which are applied to tetanic affections, do not imply so many particular diseases; but only the seat and various degrees of one and the same com- plaint. A far more important division of tetanus, is into the acute and chronic , according to its greater or lesser intensity. The first is ex- ceedingly dangerous, and usually fatal ; whiie the latter, on account of the more gradual progress of the symptoms, affords more op- portunity of being successfully treated. ( Lar - rey, in Mem. de Cliirurgie. Militairc, T. 1, p. 235, 236.; Tetanus may also be distinguished into the traumatic , or that arising from wounds, being the case with which surgeons have principally to deal; and into the idiopathic, or that proceeding from a variety of other causes. atraumatic tetanus sometimes comes or. in a surprisingly sudden manner, and quickly attains its most violent degree. The most rapidly fatal case that has ever been record- ed, is one that we have on the authority of the late Professor Robison of Edinburgh. It occurred in a negro, who scratched his thumb with a broken china plate, and died of tetanus a quarter of an hour after this slight injury. (See Rees's Cyclopaedia , art. Tetanus.) But commonly, the approaches of the disorder are more gradual, and it - slowly advances to its worst 6tage. In this sort of case, the commencement of the dis- order is announced by a sensation of stiff- ness about the neck, a symptom, which in- creasing by degrees, renders the motion of the head difficult and painful. In propor- tion as the rigidity of the neck becomes greater, the patient experiences about the root of tbe tongue, an uneasiness which soon changes into a difficulty of mastication and swallowing, which after a time became totally impossible. The attempt at degluti- tion is abended with convulsive efforts, es- pecially when an endeavour is made to swallow* liquids ; and so great is the distress which accompanies these convulsions, that the patient becomes very reluctant to renew the trials, an* refuses all nourishment. Sometimes it even inspires him with a dread of the sight ot water, and a great resemblance to hydrophobia is produced. One of the next remarkable symptoms is a very severe pain at the bottom of the ster- num, darting from this point backward to tbe spine, in the direction of the diaphragm. As soon as this pain commences, the spasms of all the muscles about the neck become exceedingly violent, and tbe head is drawn backwards or forwards, according as the contraction of the extensor or flexor mus- scles happens to be strongest ; but in the majority of cases, the hea I and trunk are curved backwards, (Royer, Traite dts Mai. Chir. T. 1 ,p. 288.) and the contractions in- creasing in force, the body is frequently raised in the form of a bow, resting upon the head and feet alone ; a state which is more particularly denominated opisthotonos. (Rees's Cyclopaedia, art. Tetanus.) At the same time, the muscles w r hich close the lower jaw, and which were affected with spasm and rigidity in the very beginning of the disorder, now contract with great pow- er, so as to maintain tbe lower jaw-bone in- separably applied to the upper one. The last state, which has been considered as a particular affection under the name of tris- mus or the locked-jaw, Boyer conceives may be regarded as tbe pathognomonic symptom of tetanus, which in many instances is limit- ed to such an affection of the jaw. The muscles affected in tetanic cases are never altogether relaxed, as long as the dis- ease continues ; but still they become more violently contracted in the frequent parox- ysms of spasm, which always attend the complaint, and increase as it advances. The continuance of the disease is marked by the increasing spasm of the diaphragm, which now returns every ten or fifteen mi- nutes, and is instantly succeeded by a stronger retraction of the head and rigidity' of the muscles of the back, and even of those of the lower extremities. The abdominal muscles are also strongly contracted, so that the belly feels as hard and tense as a board. By the violence of the contractions, indeed, tbe recti muscles have been known to be lacerated, as l shall relate an example of hereafter. Sometimes the spasm and ten- sion extend only to the muscles on one par- ticular side of the body : the tetanus lateralis of Sauvages, and the pleuroslholonos of other nosologists. When the disease reaches its most violent stage, the flexor muscles of the head and trunk contract so powerfully, that they counterbalance tbe force of tbe extensors, and hold tiiose parts in a straight, fixed, im- moveable position. This is the condition to which the appellation of tetanus more par ticularly belongs. The muscles of the lower extremities become rigid ; and even the arms, which till now were little affected, also partake of the general spasm and stiff- ness, with the exception of the fingers, which often retain their moveableness to tbe last. The tongue likewise continues a long while endued with the power of volun- tary motion ; but. at length, the viol err T ETA IN OS. -HiS spasms do not leave it unaffected, and it is then liable to be forcibly propelled between the teeth, where it is sometimes dreadfully lacerated. In the extreme period of the disorder, all the muscles destined for voluntary motion, are affected ; among others, those of the face ; the forehead is drawn up into fur- rows ; the eyes, sometimes distorted, are generally fixed and motionless in their sock ets ; the nose is drawn up, and the cheeks are retracted towards the ears ; so thai the features undergo a most extraordinary change When tetanus arrives at this stage, and the spasms arc universal, a violent con- vulsion usually puts an end to the patient’s misery. Wherever the muscular contractions are situated in cases of tetanus, they are always accompanied with the most , excruciating pain. They sometimes last, without any manifest remission, to the end of the disor- der ; but in almost all cases, their violence, and the sufferings excited by them, undergo periodical diminutions every minute or ttto. The relaxation, however, is never such as to let the muscles, which experience it yield to the action of their antagonists ; and it is in nearly all cases followed, in ten or twelve minutes, by a renewal of the previous con- tractions and suffering. The recurrence of these aggravated spasms frequently happens, without any evident cause; but it is often determined by efforts which the patient makes to change his posture, swallow, speak, &c. As Dr. Cullen observes, the attacks of this disease are seldom attended with any fever. When the spasms are general and violent, the pulse is contracted, hurrie 1 . and irregular, and the respiration is affected in tike manner; but during the remission, both the pulse and respiration usually return to their natural state. The heat of the body is commonly not increased ; frequently the face is pale, with a cold sweat upon it ; and very often the extremities are cold, with a cold sweat over the whole body. When, however, the spasms are frequent and vio- lent, the pulse is sometimes more full and frequent, than natural ; the face is flushed, and a warm sweat is forced out over the_ whole body. “ Although fever be not a constant attend- ant of this disease, especially when arising from a lesion of nerves ; yet in those cases proceeding from cold, a fever sometimes .has supervened, and is said to have been attended with inflammatory symptoms. Blood lias often been drawn in this disease, but it neve? exhibits any inflammatory crust ; and all accounts seem to agree, that the blood drawn seems to be of a looser texture than ordinary, and that it does not coagu- late in the usual manner. “In this disease the head is seldom af- fected with delirium, or even confusion of thought, till the last stage of it ; when by the repeated shocks of a violent distemper, every function of the system is greatly dis- ordered /tfk “ It is no less extraordinary,’ that in tin. violent disease the natural functions are not either immediately or considerably affected. Vomitings sometimes appear early in the disease but commonly they are not conti- nued ; and it is usual enough for the appe- tite of hunger to remain through the whole course of the disease ; and what food hap- pens to be taken down seems to be regularly enough digested. The excretions are some- times affected, but not always. The urine, is sometimes suppressed, or is voided with difficulty and pain. The belly is costive; but as we have hardly any accounts, ex- cepting of those cases in which opiates have been largely employed, it is uncertain whe- ther the costiveness has been the effect of the opiates or of the disease. In several instances of this disease a miliary eruption , has appeared upon the skin, but whether this be a symptom of the disease, or the ef- fect of a certain treatment of it, is undeter- mined. In the mean while, it has not been observed to denote either safety or danger, or to have any effect in changing the course of the distemper. ’’ — ( First Lines of the Prac- tice of Physic , Vol. 3.) According to Baron Larrey, the opistho- tonos is not so often observed in Egypt as the einprostbotonos, and the experience of this gentleman taught him that the former was the most rapidly fatal. We must not adopt, however, his curious opinion, that the violent extension of the vertebra? of the neck, and the manner in which the head is thrown back, cause strong compression of the spinal marrow, and a permanent con- traction of the larynx and pharynx, (Mem. dc Chirurgie Militaire, T. 1, p. 240.) since this sort of compression, if it did not at ^ice destroy the patient, would at any rate jroru lize most of the muscles, and instantly stop their extraordinary contraction. This experienced writer notices how much the nerves of the neck and throat seetn generally to be affected on the inva- sion of this disease. The consequent con- traction of the muscles of these parts, he says, is soon attended with difficulty of de- glutition and respiration. The patients then experience, if not a dread of liquids, at least a great aversion to them, which often pre- vents the administration of internal reme- dies ; and if the wound is out of reach of the interference of art, (he patient is doom- ed to undergo the train of sufferings attend- ant on this cruel and terrible disorder. No- thing can surmount the obstacles which present themselves in the (esophagus. The introduction of an elastic gum-catheter into this canal, through the nostrils, is followed hy convulsions and suffocation. “ I have tried this means (says Larrey) on the per son of M. Navailh, a surgeon of the second class, who died of a locked-javV, brought on by a wound of the face, accompanied with a comminuted fracture of the bones of the nose,' and part of the left orbit. “ In the examination of£fe bodies of pri- son's dead of tetanus, I have found the pha rynx and oesophagus much contracted, and TETAMj:- their internal membrane red, inflamed, and covered with a viscid reddish mucus. “ Hydrophobia, hysteria, and several other nervous diseases, likewise produce their chief effects upon these organs, and the result appears to be the same. So, I have just remarked, when tetanus is ar rived at its worst degree, the patients have a great aversion to liquids, and if they are forced to swallow them, immediate convul- sions are excited. This circumstance was particularly observed in M. Navailh.” — (Mm. da Chirurgie Mi lit air e, T. 1, p. 247, 248.) Sometimes tetanic affections deviate from their ordinary course and nature. The most singular of these anomalies is recorded by Sir Gilbert Blane ; it is a case in which tetanus prevailed to a very considerable extent, without any degree of pain. The spasms were accompanied with a tingling sensation, which was even rather agreeable than dis- tressing. The case, however, terminated fatally ; but, to the last, no pain was expe- rienced. In two examples, mentioned by the same author, the spasms affected only the side of the body in which the wound was situated. The dissection of patients who have died of tetanus, has thrown no light upon the nature of this fatal disorder. Sometimes slight effusions are found within the cra- nium ; but, in general, no morbid appear- ance whatever can be detected in the head. There is always more or less of an inflam- matory appearance in the oesophagus and in the villous coat of the stomach about the cardia. But those who are conversant a ith dissections must be well aware, that these appearances are common to a great num- ber of diseases, and are uniformly met with in every case of rapid or violent death. Besides the redness and increased vascula- rity of these parts, Baron Larrey, as I have, already stated, found the pharynx and oeso- phagus much contracted, and covered with a viscid reddish mucus. He also found nu- merous lumbrici in the bowels of the- seve- ral patients who died. — (See Mem. de Chir. Mililaire, T. 3 ,p. 2S7.) This, however, could only be an accidental complication, and not a cause. In several cases, Dr. M’Arthur found the intestines much inflamed, and in two of them a yellow, waxy fluid, of a pe- culiar offensive smell, covered their internal surface : but whether the inflammation was primary, or only a consequence of the pres- sure erf the abdominal muscles, which con- tract so violently in this disease, he is una- ble to decide, — (See Med. Chir. Trans. Col. 7, p. 475, and Rees's Cyclopaedia , art. Teta- nus.) Dr. Lionel Chalmers, of Charleston, South-Carolina, states, that when the disease forms very quickly, and invades the unfor- tunate persons with the whole train of its mischievous symptoms, in a few hours, the danger is proportioned to the rapidity of the attack, and that the patients thus seized, generally die in 24, 3o, or 48 hours, and very rarely survive the third day. Rut 469 when the. disease is less acute, few arc lost after the ninth or eleventh. (See Mid. Ob s. and Imp Vol. 1 , p. 92, 93.) From the valuable report of Sir Jamc Macgrigor, it appears, that several hundreds of cases of tetanus occurred in our army, during tiie late campaigns in Spain and Por- tugal. The disease was observed to come on at uncertain periods after the receipt of the local injury ; but it terminated on the second, third, and fourth days, and even as late as the seventeenth and twentieth day ; though it was usually not protracted beyond the eighth. (Med. Chir. Trans. Vol. 6, p. 353.) — 1 had a patient, however, who lin- gered in the military hospital at Oudenbosch five weeks, with chronic tetanus, before he died. This happened in the year 1814, soon after the assault on Bergcn-op-Zoom, where the patient had been wounded, and suffered amputation of the thigh. Although tetanus is a disease which has been observed in almost ail parts of the world, experience proves that its frequency is much the greatest 1 in warm climates, and especially in the hot seasons of those cli- mates.- It is also more common in marshy situations, and countries bordering upon the ' sea, than in places which are very dry, ele- vated, and at a distance from the sea-coast. Every class of individuals is exposed to its attacks , but infants, a few days after their birth, and middle-aged persons, are said to be oftener affected than older subjects, or others in the youthful period of life. The male sex more .frequently suffer than the female ; and tiie robust and vigorous more frequently than the weaker. According to Dr. Cullen and other medi- cal writers, the causes of tetanus are cold and moisture applied to the body while it is very warm, and especially the sudden vicis- situdes of heat and cold. Or the disease is produced by punctures, lacerations, or other injuries. Cullen admits, however, that there are probably some other causes, which are not distinctly known. Baron Larrey observed, that gunshot wounds in the course of the nerves, and injuries of the joints, often produced teta- nus in the climate of Egypt, particularly when the weather, or temperature, passed from one extreme to the other, in damp situations, and in those— which were adja- cent to the Nile, or the sea. What he terms dry and irritable temperaments, were the most subject to the disorder, the event of which was found to be almost always fatal ( Larrey , Op. et Loc. cit.) ' Traumatic tetanus is remarked to proceed oftener from wounds of the extremities, than from similar injuries of the trunk, head, and neck. Sometimes it originates at the moment of the accident, as in the instance mentioned by die late Professor Robison of Edinburgh ; but in general, it does not come on till several days afterward, some- times not till the wound is nearly or per- fectly healed, and free from all pain and uneasiness. Wounds of every description may give rise to tetanus, and in warm cli TETANUS. mates, very trivial injuries produce it. Thus, in Egypt, Larrey had one case which pro- ceeded from the lodgment of a small piece of fish-bone in one of the sinuses of the fauces. ( M6m.de Chir urgie Militaire, T. 1, p. 254.) There can be no doubt, however, that in colder regions, traumatic tetanus seldom happens except from contused, punc- tured, or lacerated wounds ; or wounds of the ginglimoid joints, with iaceration of the tendons and ligaments ; compound fractures, or dislocations; deep pricks in the sole of the foot ; and especially lacerations of the fingers and toes. A partial division of a nerve has been suspected as a cause ; but as some nerves must be imperfectly cut through in almost every wound, and yet tetanus does not arise, the reajity of this cause is doubtful. Besides, if it were true, the cure would be easily effected by making the division of the nerve complete, which experience contradicts. Baron Larrey, how- ever, has recorded a fact, which favours the opinion, as I shall presently notice. The inclusion of the nerves in the ligatures ap plied to arteries is another alleged cause of tetanus; but as this fault is very "common, and tetanus rather rare in this country, while it may follow all sorts of wounds, whether accidents or operations, the accu- racy of this opinion may also be doubled. In support of it, however there are some cases and observations adduced by Larrey, which will be quoted in the sequel of this article. (See T. 3, of his Mem. de Chir. Mil.) I do not mean to hint, however, that the nerves are not sometimes tied in tetanic cases, or that the practice is not on every account blaineable. Amputation and cas- tration are the only great surgical operations to which 1 have seen tetanus succeed ; though it may follow the- employment of the knife on less severe occasions. In warm countries, tetanus is an ordinary consequence of all kinds of wounds. There cannot be a doubt, that difference of climate makes considerable difference in the degree and danger of tetanus. Larrey found, that in Egypt the disease was more intense, and bore a greater resemblance to hydrophobia, than in the colder climate of Germany. In both these countries, he re- marked, tiiat when the wounds causing te- tanus, injured nerves situated on the fore- part of the body, emprosthotonos was occa- sioned ; that if the posterior nerves were .hurt, opisthotonos followed ; and that when the wound extended quite through a limb, so as to injure equally both descriptions of jierves, complete tetanus ensued. lie no- ticed, also, that the disease commonly arose from wounds, when the seasons and tempe- rature passed from one extreme to another. Exposure to the cold damp nocturnal air, he found particularly conducive to it. (Bee jtfthn. de Chirurgie Militaire, T. 3. p. 286.) In the late campaigns of our armies iri Spain and Portugal, according to the report of Sir James Macgrigor, tetanus occurred in every description, and in every stage of wounds, from the slightest to the, most for- midable : it followed the healthy and Jhfe sloughing ; the incised and the lacerated , the most simple, and the most complicated. It occurred at uncertain periods ; but it was remarked, that if it did not commence before 22 days from the date of the wound, the patient was sate. (See Med. Chir. Trans. Vcl 6 , j>. 453.) Li Egypt, as we learn from Larrey, the latest period of the commence- ment of tetanus after a wound, was from the filth to the fifteenth day. {Mem. dc Chir. Militaire , T. l,p. 263.) It is observed by Dr. Dickson, that as the acute toi m ot tetanus is so uniformly fatal, it is ot the greatest consequence to attend to whatever may assist in detecting the dis- ease early, or in warding it off. Ricberand states, that in wounds threatening convul- sions and tetanus, a persevering extension of the limbs during sleep often manifests itself, before any affection of the lower jaw and we should naturally pay more attention to any admonition of this kind in punctured, or extensive lacerated wounds, particularly of tendinous, or ligamentous parts, and es- pecially in injuries of the feet, hands knee- joint, back, &c. Some prelusive indications of danger may often be derived from the increase of pain, irritation, restlesness, ner- vous twitchmgs, pain and difficulty in de- glution, or in turning the head ; spasms, or partial rigidity of some of the voluntary muscles : pain at the scrobiculus cordis ; a suppressed, or vitiated state of the discharge. &c. which mark the slower approaches of the disease. Larrey adduces several in- stances of telanus, in which the wound was either dry, or afforded only a scanty serous exudation, and where the symptoms were relieved on suppuration being re-establish- ed ; and Dr. Reid, in the Edinburgh Medical and Surgical Journal for July 1*15, remarks, that on removing the dressing, the wound was covered with a darkish unhealthy-look- ing matter, and that he had seen this change the forerunner of tetanus in two other in- stances. A torpor of the intestines has ge- nerally been observed to precede, as well as accompany the disease, and Boyer, in particular, enumerates an obstinate cousti pation among the predisposing causes. {Traiti des Mai. Chir. '/’. I, p. 287.) Mr. Abernethy also informs us, that in four cases where he inquired into the state of the bow- els, the evacuations were not like feces; and he proposes as a question, in investiga- ting the cause, what is the state of the bow- els between the infliction of the injury, and the appearance of this dreadful malady {Abernethy' s Surgical Works. Vol. 1, p ■ 1R4.) Dr Parry thinks the velocity of the circula- tion an useful criterion of the danger of the disease, and observes, tiiat if the pulse be not above 1(H), or 1 10, by the fourth or fifth day, the patient almost always recovers; but that it it be quickened early, the disease mostly proves fatal, and yet there are a few instances of recovery, where the pulse has risen to 120 on the first day. Baron Larrev remarks, that when the perspiration, which so often attends the disease is symptomatic iKTAiNiJS it begins upon the iiead ami extremities; but that when it is critical, it occurs over the chest and the abdomen. ( Mtmoires de Chir. Militaire , T. 1 ,p. 256.) It must be confess- ed, however, that in many cases, perspira- tion Hows very freely, without bringing re- lief. ( Rees's Cyclopaedia, arl. Tetanus.) I next proceed to consider the treatment of tetanus a subject of infinite difficulty, be- cause the disease frequently baffles every mode of practice, and in certain instances, get well under the employment of the very same remedies, which decidedly fail in other similar cases of the disorder. Every plan has occasionally succeeded, and every plan lias still more frequently miscarried. The great difficulty, therefore, is to ascertain, among numerous discordant accounts, what practice is found on the whole to be attend- ed with the least ill-success? For, in the pre- sent state of our knowledge, the most cre- dulous practitioner will not flatter himself with the supposition, that any effectual re- medy for tetanus has yet been discovered. As, however, tetanus was regarded by Hip- pocrates and the ancients as certainly mor tal, and it does not always prove so in mo- dern times, it seems allowable to conclude that the recoveries, which now happen, must be ascribed to improvements in prac- tice This reflection should lead us not to give up the subject as hopeless ; but to re- double our exertions for the discovery of a more successful method of treatment, and if possible, of some new medicine, possess- ing more specific power over the disorder. As it is justly observed by a well-inform- ed writer, w hen we reflect upon the obscu- rity which involves both the ratio sympto- matum , and the proximate cause of tetanic affections, we need not wonder, that the practice in these disorders should still be entirely empirical. The indication of cure, which is generally applicable in all diseases, namely, the removal of the exciting causes, has but little place in a morbid condition, which is the consequence of causes, that in general have ceased to act, or which it is not in our power either to remove or con- trol. In those cases, where we could sup- pose local irritation to be still operating, the most effectual method o£ counteracting its effects on the system, would obviously be to intercept all communication between the seat of the irritation and the sensorium. If, however, the disease has already esta- blished itself, and the severe symptoms have come on, it does not appear that this would succeed iti arresting the course of the disor- der. Experience has but too fully shown, that the amputation of the limb, from the injury of which the tetanus has arisen, will very seldom procure even a mitigation of the symptoms, if performed after a certain period from their first appearance. ( Rees's Cyclopaedia, art. Tetanus.) Baron Larrey has been the greatest modern advocate for the performance of amputation in cases where tetanus depends upon a wound of the extremities ; but the facts which he has ad- duced in its favour are not numerous, and 4U he limits lus recommendation of ike measure chiefly to chronic cases, and extends it to ho others, except on the very first accession of the symptoms. “ The equally unexpected and entire suc- cess (observes Larrey,) obtained by the am putation of the injured limb, in the person of an officer attacked with chronic tetanus, leads me to propose the question, whether , in this disorder, occasioned by a wound of sme part of the extremities, it would not be better to amputate the injured limb immedi- ately the symptoms of tetanus commence, rather than expect from the resources of nature, and from very uncertain remedies , a cure which so seldom happens ? u If tetanus is chronic, as is sometimes ob- served. amputation may be done at every period of the disorder, provided a choice be made of the time when there is an inter- mission of the symptoms. The operation would not answer so well in acute tetanus, if the disease were advanced, and the mus- cles to be divided were strongly contracted and rigid, as l have observed at the siege of Acre in a soldier, who was seized with teta- nus in consequence of a gun-hot wound of the left elbow.” ( Mim.deChir . Militaire. T. 1 ,p. 262.) Larrey did, indeed, try amputation in a few instances of acute tetanus. In the case last cited, the symptoms were already considera- bly advanced, when the experiment of am- putating the arm was made ; yet, says Lar- rey, the operation was followed by consider- able ease. The symptoms recurred, how- ever, a few hours afterward, and proved fatal on the third day. In another example, this gentleman repeated the experiment, though acute tetanus had begun, 'the ope- ration is described as having stopped all the symptoms, as it were, by enchantment ; the patient even passed twelve hours in perfect ease ; but being exposed to the damp cold air, the disorder returned, and carried him off. (See Mem. rle Chirurgie Militaire, T. 1 , j p. 263 — 269.) The Baron also records some cases in favour of amputation at the com mencementof tetanus from wounds, and es- pecially for (he relief of the disease in the cliroruc form. He has likewise adduced an interesting example, in which speedy relief and a cure followed cutting off’ all commu- nication between the nerves of the wound ed part and the sensorium by a suitable in- cision. In this place I think it right to remind the reader, that although Baron Larrey once or twice amputated when acute tetanus was somewhat advanced, he does not advise the practice, and he expressly restricts his sanc- tion of amputation to chronic or quite inci- pient ( ases of tetanus, and to a few instances in which the ginglimoid joints are fractured, accidents, which, independently of tetanus, would generally require the operation. (See Mem. de Chir. Mil. T. 3.) The report of Sir James Macgrigor fully confirms the stale; ent of 1 jarrey ; namely, that free incisions are of little avail in the acute and fully formed disease, and that amputation fails in the same TETANUS. "kind of case. After Ihe battle, of Toulouse, this operation was extensively tried ; but without success. Th>' French are also. said to have lo3t an immense number of s Idieis from tetanus after I lie battle of Dresden, when S i James infers that the practice, of amputation must have been fairly tried. (See Medico -Chir urgica l Trans. Vol. 6, p 456.) We have seen, however, that according to the precepts of Larrey, (lie French -urgeons would only have performed the operation in chronic cases, which are not the most fre- quent, or if in other instances only on the very first accession of Ihe symptoms. Bui upon the whole, notwithstanding the partial degree of success attending Larrey’s experi- ments, I have no hesitation in declaring my belief, that amputation of the i jured part in cases of chronic tetanus will never be exten- sively adopted. Tne uncertain efficacy of this severe measure, and the occasional pos- sibility of curing this form of the complaint by milder (dans, will tor ever constitute insu- perable arguments against the practice. Since the last edition of this Dictionary was printed, Sir Astley Cooper has published his sentiments respecting the plan of ampu- tating in cases of tetanus, and ihpy tend to confirm tRF opinion which I have always given upon the subject. In one case of te- tanus, i rom a compound fracture just above the ankle, the operation seemed to precipi- tate the fatal event. In another case, the finger was amputated without any good ; and a third case is referred to, in which the ope- ration also failed in saving the patient's life. In chronic tetanus, amputation is regarded by Sir A. Cooper as unjustifiable, as the pa- tient often recovers w ithout this proceeding. The medicine which has appeared to this gen- tleman most useful in Mich cases, is the sub- muriate of rne cuiy, joined with opium (Surgical Essays. Part 2 ,/>. 190.) On the subject of making incisions for the purpose of separating the nervps of the wounded part from the seusorium, Larrey states, that they should be practised before inflammation lias come on ; for if this has made progress, (hey would be useless, and even dangerous. They should comprehend, as much as possible, all the nervous filaments and membranous parts ; but he cond- m ns all incisions into joints, as exasperating the symptoms of tetanus, instances of which lie has witnessed.. The Baron has recorded some convincing proofs ot the benefit some- times arising from completely dividing the trunk of the injured nerve.' in one instance, tetanic symptoms followed an injury of the supraorbitary nerve, but were immediately slopped by dividing some of the fibres of the occipito-frontalis, and the nerves and vessels, down to the bone. On the principle of destroying the. parts, which are Ihe scat of the local irritation, Banm Larrey also frequently applied the actual and potential cautery to the wound. The application ot caustics, says he, may be practised with advantage on the lit si attack of the symptoms, the same precept being ob- served as in making the incision: Bleeding, if necessary, and the use ot topical emollients and anodynes, may follow these operations , though in general they have little effect (Man. de. Chir. Militairc , T.\,p. 249.) In the third volume ot this interesting work, p. 297 are several cases', in which the cautery was employed with success. We must not conclude, however, that much dependence ou ht ain j and the convulsive twitchings, which sometimes accompany the complaint. The dhuses of tic douloureux may be said to be in general unknown ; but there are a tew instances recorded which appear to be the consequence of external violence, wounds, contusions, &c. A modern writer has related a very curious instance of a re- sembling disease in the arm, where the af- fection proceeded from the lodgment of a small bit of a bullet in the radial nerve. ( Den - snark, in Med. Chir. Tram. Vol. 4, p. 48.) Dr. Parry attributed the pain to increased vascularity, or determination of blood, (per- haps amounting to inflammation) to the neu- rilerna, or vascular membranous envelope of the nerves affected. {Elements of Pathology and Therapeutics.) Stimulating embrocations, blisters, caustic issues, fomentations, leeches, frictions w ith mercurial ointment, ( Edinb . Med. and Surg. Journ. Vol. 3,) electricity, opium in large doses, the arsenical solution, and a variety of antispasmodic medicines, are the princi- pal means, which have been tried ; but for the most part, they only afford partial and temporary relief. From some facts recent- ly published by Dr. Marcet, the extract of stramonium, in doses of one-eighth and half a grain thrice a day, seems to be sometimes capable of alleviating the distressing agony of the present disorder. (See Med. Chir. Trans. Vol. 7, p. 75, fyc. also Kirby's Cases , S vo. Lond. 1819.) The operation of dividing the trunk of the affected nerve, and even of dissecting out a portion of it, so as to prevent all chance of a relapse from the reunion of the ends of the nerve, is a plan, which has sometimes been practised with permanent benefit. Thus, any one of the three branches of the fifth pair of nerves may be divided at the point, where it comes out upon the face. But, before having recourse to this means, the surgeon should be sure, that the particular nerve, which he is about to expose and divide, is really the prin- cipal seat of the disease ; for, when all the nerves of the face generally are affected, or when the branches of the portio dura are especially concerned, there is little hope of success. In fact, it must be confessed, that the operation has had many failures and re- lapses, either from the cases not having been duly discriminated, or from the neglect to remove a portion of the exposed nerve. Richerand, Delpech, and most of the lead- ing surgeons in France express their prefe- rence to the application of the moxa, or cautery, which, they say, proves more fre- quently successful, than the knife. This should be done directly over the apertures, from which the nerves emerge on the fore- head, cheek, or chin, and Richerand asserts, that by such treatment, the pains may al- ways be cured, or at all events, rendered supportable. ( Nosogr . Chir. T. 2, p 218, Edit. 4.) Delpech also affirms, that the sec- tion of the nerve very often fails, and that issues, and the repeated use of the cautery have been attended with the greatest suc- cess. (See Pr6cis dzs Mai Chir. T. 3, p. 213 > Vol, II, <51 The disfigurement of the countenance by burning applications must, how’ever, be very objectionable, and, as I think there is no positive evidence of the superiority of this method over the use of the knife, l consider what Richerand and Delpech have staled only as another instance of the extreme partiality of the French surgeons to the moxa and cauterization. Delpech confesses, however, that, when the pains seem to be the consequence of a ganglion, or thicken- ing of a part of a nerve, the excision of such part is indispensable. There can be little doubt, that this would have been more proper than amputation in Mr. Denmark's case, to which I have already referred. The theories of Dr. Parry, senior, who was generally inclined to refer the effects of dis- ease to increased determination of blood to the parts affected, led him to believe that the operation of cutting the nerve, as performed by Dr. [faighton and others, did good rather by the division of the arterial branch sup- plying the affected ramification of the trige- minus nerve, than by the division of that ra- mification itself. {Parry, Elements of Pa- thology, fyc.) There have been many examples of tic douloureux, which, after resisting all at- tempts to cure them, have been left to them- selves, and, after a long time spontaneously subsided. ( Delpech , Traite des Maladies Chir. T. 3, p. 212, 215.) This author has seen the operation of dividing the chief branches of the portio dura, in front of the parotid gland, undertaken, and even a por- tion of the soft parts cut away ; but without any favourable consequences. (P.218.) I have already stated, that the nerves of the extremities are subject to affections very analogous to tic douloureux. The following instance related by Mr. Abernethy will be found interesting ; — A lady became gradually affected with «• painful state of the integuments under, and adjoining to, the inner edge of the nail of the ring-finger of the left hand. No injury to the part was remembered, which could have brought on this disease. The pain oc- curred at irregular intervals, and was ex- tremely severe during the time of its con- tinuance, which was fora day or two, when it usually abated. Accidental slight injuries always produced great pain, and frequently brought on the paroxysms, which however occasionally occurred spontaneously, or without any evident exciting cause. In all these particulars, the disease correctly re- sembled the tic douloureux of the nerves of the face. As the pain increased, the disor- der seemed to extend up the nerves of the arm. After the patient had endured this painful affliction for seven years, she sub- mitted to have the skin, which was the ori- ginal seat of the disorder, burnt with caustic. This application gave her intense pain, and on the healing of the wound, she found her sufferings rather augmented than diminished, by the experiment. After four more years of suffering, she consulted Mr. Abernethy, when the circumstances of the case wert 4 *: TOE TIC such as to render an operation indispensably necessary. The pain of the part was into- lerable, and it extended all up the nerves of the arm ; and this general pain was so con- stant during the night, as to deprive the pa- tient of rest. The muscles of the bach of (he neck were occasionally affected with spasms. The integuments of the affected arm were much hotter than those of the opposite arm, and sometimes the temperature was so in- creased as to cause a burning sensation in them. Underthese circumstances, Mr. Aber- nethy did not hesitate to divide the nerve of the finger, from which all this disorder seem- ed to originate.' He laid it bare by a longi- tudinal incision of about three quarters of an inchin length, from the second joint of the linger, and divided it opposite to that joint, by a curved sharp-pointed bistoury, which xvas conveyed under it. He then took hold of the nerve with a pair of forceps, and re- jecting it downwards, removed a portion of it, half an inch in length, so that the possibi- lity of a quick reunion might be prevented. The wound was brought together with stick- ing plaster, and it united by adhesion ; but the upper part of the wound, opposite to the upper end of the nerve, became slightly in- flamed, and was very painful. However, in the course of three weeks, ihe appearance of inflammation gradually went off. After the operation, Mr. Abernethy pinched the originally affected integuments sharply with bis nails, without causing any sensation ; but if, in so doing, he moved the finger, then pain was felt. He found it difficult to con- vince the patient that the skin at that part was actually devoid of sensation ; for she still continued to feel similar sensations to those which formerly occurred, though in a much diminished degree; but she became gradually as perfectly convinced as any me- dical man could be, that these sensations arose from (he irritated state of the end of the nerve, above the place where it was di- vided. The painful affection of the nerves of the arm still continued, though considera- bly lessened in violence ; however it was suf- ficiently severe to make the patient appre- hend that little permanent benefit would arise from the operation. This pain conti- nued occasionally about four months with varying degrees of severity, but the tempe- rature of the skin was not hotter than that of the opposite side, as it hhd been before the operation. At the expiration of three months, the patient ascertained that the in- teguments at the end of the finger actually felt when any thing was applied to them, arid this proved a new source of alarm. Mr. Abernethy adds, that mure than nine months have now elapsed since the performance of the operation, and the general pains in the nerves have become very trivial ; but the sensation in the integuments at the end of the finger, has during that time gradually in- creased, and the skin has now its natural sensibility, so as accurately to distinguish the tangible properties of any body applied to it. If also the originally affected part be slightly compressed, painful sensations re- sembling those which formerly occurred take place. (Mernethy's Surgical Work Fol. 2, p. 203.) In a case resembling the former, but the consequence of a wound of the finger, M . Laurence also cut down to the nerve, and removed » portion of it wi‘h per- manent success Father fill's Paper in ol. 5 of the Medical Ohs. and Inq. Dr. Haigh - Ion's Obs. in Ihe Med. Recants and Researches . Darwin's Zoononia. JlbenvAhf s Surg. Works, Fol 2, p. 20*3, fyc. Richerand, No- sogr. ( hir . T. 2 p. 216. ifc. Edit. 4. Del- pech, Precis des Maladies Chir. T. 3, p. 206, fyc. Dr. S Fothergill'.s Systematic Account of Tic Douloureux, 1804. Mcdico-Chir. Trans . Fol 4, p. 48, Fol. 7, p. 575, fyc. Kirby's Cases, 8vo. Lond. 1819. TINCTURA KERRI MURIATIS. This tincture has sometimes been exhibited in gleets ; but a more important use has been assigned it by Mr. Cline, who orders it in dysuria from stricture, in the dose of ten drops every twenty or thirty minutes, until nausea is excited. Where chalybeates are indicated, (his preparation is one very much approved of “ Mr. Justamond^s liquid for external use in cancers, and which the original inventor called his panacea anticancrosa, partook con- siderably of the nature of this tincture, which, indeed, with an equal quantity of spirit ol wine, was sometimes substituted for it, “ Lastly, it is remarkably efficacious in destroying venereal or other warts, either used alone, or diluted with a small propor- tion of water ” ( Pharm . Chir.) TINCTURA LYTTdS. Sometimes em- ployed in cases of gleets, and incontinence of urine, arising from a want of proper ac- tion in the sphincter vesicae muscle. The usual dose is from ten to forty drops, twice or thrice a day ; but its effects should be carefully w atched ; for it is apt to occa- sion dangerous inflammation* of the urinary organs, violent stranguries, and retention of urine If is occasionally used in various liniments, when die object is to stimulate the skin considerably, and rouse the action of the nerves and absorbents, as in certain ca- ses of ptosis, paralysis, &,c. Mr. Anthony Todd Thomson has found it an useful appli- cation in the mortification of the extremities, sometimes happening without any apparent cause ; and also to frost-bitten parts. ( Lon- don Dispensatori /, p. 65S, Ed. 2.) TINCTURA THEBAIC A. (See Vinum Opii.) TINEA CAPITIS. (See Porrigo.) TOBACCO is used for promoting the re- duction of strangulated hernia, either in the form of a fluid clyster, or of smoke, which latter is introduced up the rectum by means of an Apparatus. Excepting the operation, the power of tobacco, particularly, when assisted by the topical application of cold to the tumour, is most to be depended upon for bringing about the return of the protru- ded viscera. (See Hernia, and Enema.) It has also been tried in tetanus ; and Mr. Earle has found tobacco clysters very efficacious in certain cases of retention of urine. (See Tetanus, and Urine , Retention of.) Consult T Fowhr . Medical Reports of the Effects of TONGUE Tobacco, Svo. Lond. 1785. A. P. Wilson, An Experimental Essay on the manner in which Opium and Tobacco act on the living animal Body, Svo. Edinb. 1 795. It. Hamilton , He JYicotiams Viribus in Medicina, fyc. Svo. Edinb. 17S0. TONGUE, DISEASES OF. This part is subject to various diseases, as ulcers, tu- mours, and such enlargements as sometimes put the patient in imminent danger of suffo- cation. Carious teeth, with points and inequali- ties, producing continual irritation, are the most frequent cause of ulcerations of the tongue. The sores, thus arising, often re- sist every kind of remedy, and ignorance of the cause sometimes leads the practitioner to consider them as incurable ; whereas, a cure may easily be effected by extracting the carious tooth, or simply filing off its sharp irregularities, as was anciently direct- ed by Celsus. The glandular papillae which are situated on the dorsum, or upper surface of the tongue, have a narrow base, and a broad termination or head, like a mushroom. They are capable of becoming considerably enlarged, so as to form preternatural tumours, which may be mistaken for can- cerous excrescences. A young man, eighteen years of age, had on the middle of his tongue a circumscribed tumour, about as large as a middle-sized nutmeg. Louis, who was consulted, per- ceived that the swelling was only of a fun- gous nature, and he tied its base with a liga- ture, with the noose of which he con- tracted the diameter of the pedicle, while, with the ends, he kept down the tongue. Then with one stroke of a pair of cur- ved scis ors, he cut off the tubercle. Caus- tic was afterward applied to the base of the tumour, and the patient was. perfectly well in five or six days. ( Sur les Maladies de la Langue, in M6 moires de I'Acad. de Chir. f.b.) Morgagni speaks of similar tubercles ; but he never advised their extirpation, not even when they were hard and scirrhous ; for, if he had not deemed the operation im- practicable, he should not have had any confidence in the surgeons who were .con- sulted. The tongue is occasionally affected with a true cancerous disease*, one of the most afflicting cases, indeed, which can possibly happen, as may be conceived, when it is known, that, in the advanced stage of the disease, the patient can hardly take his food, which must be conveyed over the tongue by some means or another, before it can be swallowed, while he is obliged to w r rite what- ever he wishes to say. (See Home's Pract. Obs. on Cancer , p. 112.) Cancer of the tongue seems to differ from other carcino- matous affections in frequently occurring in youngish subjects. In the course- of the disease, the glands behind the jaw and in the neck are sometimes affected. Louis saw a lady, who had an ulcerated cance- rous tubercle on the left edge of the tongue. The little swelling was circumscribed, , ; *its 483 size did not exceed that of a filbert; the pains were lancinating ; the sore had pene- trated deeply ; and its tuberculated edges were affected with a scirrhous hardness. Extirpation of the disease seemed to present the only chance of cure *, but the patient refused to accede to any thing but palliative plans, and she died in the course of a few months. Forestus makes mention of four women, who were attacked with cancer of their tongues, and died from the ravages of the disease, and hemorrhage. In the writings of Hildanus, there is a description of the origin and progress of a cancerous tubercle on a young man’s tongue, whose breath was intolerably fetid and who died in the most excruciating pain. The same author informs us of another case, exhibiting the good effects of sedative remedies in palliat- ing a cancerous ulcer of the tongue, and the fatal consequences of an opposite line of conduct. In authors, many other ex- amples of the same kind are to be met with. Surgery, however, is not destitute of re- sources against diseases of so formidable a nature. The following case exemplifies the benefit which may be effected by this useful profession, when not exercised by men of too timorous a character. An elderly woman had an ulcerated hard- ness on her tongue. It had been several, times cut away, and as repeatedly returned.. Ruysch was called into consultation with one of the surgeons, who was attending the patient, and who had already extended his incisions very deeply for the removal of the disease. The result of their deliberations was another attempt to extirpate the tu- mour, and they also determined that after it had been cut away, the actual cautery should be freely applied, with a view of destroying the roots of the fungus. The pa- tient consehted to the plan, and bore the operations with great fortitude. The tongue was taken hold of with a cloth, and Pierre Le Memnonite, a sufgeon of emi- nence, removed the disease with a curved bistoury. The inside of the mouth was then protected with wet cloths, and the actual cautery applied several times to the wound in the tongue. The pain was appeased, and the separation of the eschar promoted by emollient gargles. Under, the use of a gar- gle of honey of roses, and the tincture ot myrrh and aloes, the place soon healed. It is much easier to cut off a portion of the tongue, through all its diameter, than to remove a cancerous ulceration, situated-at one of its edges. In both cases, there is a good deal of dif- ficulty in fixing the part, for it is so very moveable, that it is not easy to keep it in a steady position. For this purpose, Louis re- commended the employment of forceps, with blades terminating in hook-like extre- mities. With this instrument, the part of the. tongue to be amputated can be kept from slipping away. However, very malignant ulcers on the tongue have sometimes been cured by mild- er means. Sores of this description are re- 48.4 lOXGTJE. ported t6 have yielded to the repeated ap- plication of leeches under the tongue, after a vast number of other remedies had been tried in vain. In the Encyclopedic MAlho- dique, art. Langue , there is an account of a very alarming affection of the tongue, (re- puted to be cancerous, though this may be doubted,) which got completely well under a very simple plan of treatment. A woman, thirty-five years of age, subject to cutaneous diseases, and ill-conditioned ulcers, com- plained, for seven or, eight months, of little swellings, accompanied with heat and pain, which made their appearance on the edge, and towards the apex of the tongue. At length, the part affected began to swell, grow hard, and cause lancinating pains. Its sur- face .became irregular and rough ; and all the side of the tongue was considerably swelled. The patient could not put her tongue out of her mouth, nor swallow any thing except liquids ; and her breath was intolerably fetid. Various sedative remedies had been employed without success. Ci- euta had been used as a topical application ; it had been exhibited internally in large doses; the patient had taken for a long while, the oxymuriate of mercury ; but no- thing proved of any avail. At length the palieni was so tired of trying the effects of medicines and applications, that she gave them up entirely; and contented herself with trying the experiment of keeping some ho- ney continually in her mouth. As this method seemed to give her some ease, she was pre- vailed upon to persist in it, and in this way, the pains were gradually appeased ; the swelling was diminished, and at the end of two or three months, the woman was quite well, except that an indurated cicatrix re- mained on the part affected, and considera- bly obstructed the extension of the tongue on that side. On this case, however, it might be re- marked, the retardation of the cure seem 3 also ascribable to the injury of the health produced by the hemlock, mercury, &c. and that the amendment, following their dis- continuance, might rather arise from the consequent improvement of the patient’s health, than from any effect of the honey. Many writers confirm the fact, that very inveterate diseases of the tongue are some- times cured by hemlock. Jn the work last cited, is mentioned an instance of a very unhealthy looking ulcer, near the apex of the tongue, attended with a considerable thickening of the part, and of some dura- tion, which was cured by giving large doses of cicuta. But of all the medicines which have the greatest reputation for their bene- ficial effects upon malignant ulcers of the lip and tongue, none perhaps is deserv- ing of so much confidence, as arsenic. (See C. Lane's case of iU-condilioned Ulcer of Ike Tongue , successfully treated by arsenic ; Med. Chir. Trans. Vol. 8, p. 201.) However, notwithstanding many facts, of this kind on record, medicines should not be tried too long, that is to say, so as to let the disease attain a condition, in which it will no longer admit of being cut away. When the disease makes progress, the kniie should be employed before it is too late. When any part of the tongue is to be am- putated, authors very properly recommend the chief vessels to be tied, if possible ; but when this cannot be accomplished, they advise the employment of astringent gar- gles, such as a strong solution of alum, dis- tilled vinegar, or diluted sulphuric acid. When these methods fail, the continental surgeons recommend the actual cautery as the only resource. Where only a piece of the tongue is cut out, in the shape of the letter V, the best mode of stopping tbe bleeding is to bring the sides of the in- cision together with a suture, by which means the deformity will also be lessened, and the union expedited, as is exemplified in a case recorded by Langenbeck. (Neuc Bibl. B. 2, p. 489.) Bather than suffer a patient to die of hemorrhage, if the cautery and other means fail, the lingual artery should be taken up where it passes over the cornu of tbe os hyoides. Diseased portions of the tongue admit of removal with the ligature. (La Motle Chirurgit Obs. 208; Godarl in Journ. de Med. T. 13, p. 66 ; Sir Everard Home , Pract. Obs. on Cancer , p. 207 ; Inglis , in Edinb. Med. and Surgical Journ. 1805, No. 1, p. 34.) Sir Everard Horne generally passed a double ligature through the centre of the tongue, behind the diseased portion, and then tied the threads tightly over each half of the organ, so as to make all the part in front of the constriction slough away. The whole of the tongue sometimes in- flames, and becomes considerably enlarged, either spontaneously, and without any ap- parent cause, or in consequence of some other disease ; or else from some particular irritation, such as that of mercury, or some poisonous substance. Siegel, a German physician, who was at Paris about the mid- dle of the 17th century, saw a patient in a salivation, whose tongue became so enor- mously enlarged, that the mouth could not contain it. Pimprenelle, an eminent sur- geon of that time, was sent for, and finding that all trials to relieve the affection were in vain, amputated one half of the tongue, with the view of preventing its mortifica- tion. After the wound had healed, it is said the patient could articulate very well. Louis, from whom this fact is quoted, very justly remarks, that the measure resorted to by Pimprenelle was an exceedingly violent one; for he has often seen urgent symptoms occasioned, during a salivation, by a rapid and enormous swelling of the tongue, very quickly yield to bleedings, purgative glys- ters, change of air, and leaving off meren- cury. Two or three facts, confirming this statement, have fallen under my own notice. Trincavellius mentions two women, who had considerable enlargements of their tongues. Ono of these patients, who was young, had been rubbed with mercurial ointment even on her head ; and the other, who was about fifty years old, had her tongue attacked with the ravages of the smfuLpox. The excessive swelling of the TONSILS, longue, in both these instances, terminated in resolution. When the urgency is such, that an imme- diate diminution of the swelling becomes necessary for the relief of the symptoms, the plan of making one or two deep inci- sions along the tongue is strongly recom- mended. See the cases inserted by De la Malle, in the 5th vol. 4to. of the Mem. de VAcad. Chirurgie , and some others, related by Louis in the paper above cited. A man, recovering from a bad fever, was suddenly attacked with a pain in his tongue, followed by a swelling equaliy large and rapid in its formation. In less than five hours the part became thrice as large as it is in its natural state, and in this space of time De la Malle, who had been consulted, had bled the patient successively in his arm, neck, and foot. The man felt very acute pain ; his skin was excessively hot ; his face was swelled; his pulse was hard and con- tracted ; and his look wild. He could hardly breathe: the tongue filled all the cavity of the mouth, and protruded out between the lips. In this very urgent case, the mouth was kept a little more open than the swell- ing of the tongue actually caused it to be, and three parallel incisions were made along this organ, one along its middle, and the other two between the one in the centre and the edges of the part affected. The cuts extended through two-thirds of the preternatural swelling, and had all the good effect which could possibly be desired. There was a great deal of hemorrhage, and the enlargement of the tongue subsided so much, that, an hour after the operation, the patient was able to speak. The next day the incisions had the appearance of being only superficial scarifications, and the tongue was in its natural state. In short, the inci- sions healed in a few days, with the use of a simple gargle. De la Malle quotes several other cases, all of which tend to show the success which he met with from this practice in other similar cases. He confirms his own senti- ments, by quoting the testimony of some authors, antecedent to him, who have re- commended the method ; and in particular, he cites a case, in which Job a Meckren adopted this practice, in a case where the tongue, together with the tonsils and palate, became spontaneously affected with a sud- den and dangerous degree of swelling. From the preceding observations it may be concluded, that making incisions in the tongue would have saved numerous patients, who have been suffocated in consequence of enormous enlargements of this organ. In the small-pox, the tongue sometimes be- comes immensely swelled ; and it is more than probable, that, in many instances, the employment of the above method would have afforded great relief to patients, whom the disease has been known to have entirely bereaved of the power of swallowing. It is a curious fact, that after the loss of very considerable portions, or even what may be called the whole tongue, patients often re- tlSb cover the power of speech, mastication, and deglutition. ( Louis in M6m. de VJicad. de Chir. T. 5 ; also, J. Rowland , Aglossostomo- graphie , ou Description d’une Bouche sani langue , laquelle parle, el fait naturellement toutes sts autres functions, l2ino. Saumur , 1630. Louis, sur les Maladies de la Langue t Mdmoires de VAcad. de Chir. T. 5 ; also the memoir of De la Malle in the same volume. Encyclopedic Methodique, Fartie Chir. art. Langue. Sir Ecerard Home's Fract. Obs. on C ncer,8vo. Loud. 1805. Langenbeck , JYeue Bibl. B. 2 ,p. 487, 8ro. Hanover , 1820.) TONSILS. The tonsils, like all other parts at the back of the mouth, are subject, to different kinds of swelling, which vary as much in their nature as their conseqhences. Some are rapid in their progress, and these are frequently observed to affect persons of, what is termed, a sanguineous temperament. They are also prone to attack young peo- ple, and such as labour bard, and they have all the essential characters of inflammation. Other swellings of the tonsils are slower in their progress, occur in damp cold wea- ther, and in indolent, and, what the old physicians used to call, phlegmatic consti- tutions. Lastly, another kind of enlargement of the tonsils, which is usually contagious, readily falls into a sloughing, gangrenous state, sometimes extends to the neighbour- ing parts, and too often proves fatal. Hence the various species of angina have been named by some writers inflammatory, ca- tarrhal, and gangrenous. The two first kinds frequently terminate in resolution ; but sometimes the affected tonsils after- ward assume a scirrhous hardness, obstruct respiration and deglutition, so that it be- comes indispensably necessary, either to extirpate the diseased parts with the ligature or knife. The cutting away of enlarged tonsils was an operation which was performed by the ancients, and in different ways. Sometimes they tore with their fingers the membrane covering the tonsil, and then pulled this part out of the situation which it occupies between the pillars of the velum pendulum palati. In other instances, in which they experienced too much resistance, M they sei- zed the diseased tonsil with a kind of hook, and then cut it away with a bistoury, which, Paulus iEgineta informs us, was concave on the side tow r ards the tongue. The moderns, who, for a long while, were timid in the employ ment of both these me- thods, adopted plans of a more cruel de- scription. The actual cautery was proposed, and some partial success which followed its use, at once established its reputation. Caustics were afterward employed, instead of actual fire ; but the inconvenience of not being able to limit their action, and the hazard of their falling down the oesophagus, soon caused them to be relinquished by all rational practitioners. Then the operation of cutting away the tonsils was revived, and it was performed, sometimes in the manner of the old surgeons, sometimes with various TONSILS. 486 kinds of curved scissors, or knives. Instead of the simple tenaculum used by the ancients, a sort of double one came into fashion. Bichat describes the following, as once the common plan : the surgeon is to open the mouth very wide, and depress the tongue with any flat instrument, which is to be held by an assistant. The operator is then to take hold of the diseased tonsil with a tenaculum, and with a common scalpel, having the back half of its blade covered with rag, he now removes as much of the tonsil as ought to be taken away. In com- mon cases, it is deemed sufficient to cut on a level with the pillars of the velum pendu- lum palati. Any other portion, needing re- moval, should next be taken away. The operation being finished, the patient is fre- quently to wash his mouth with proper gar- gles. The preceding method was long adopted by Desault. However, one objection is urged against it, viz. that when the end of the knife is conveyed far into the mouth, it may do mischief, not (as has been alleged) to the internal carotid artery, the backward situation of which completely keeps it out of ali danger of being wounded, but to the membranous covering of the palate, in a place not corresponding to the tonsils. De- sault thought this objection was the more forcible, as when the hook is introduced in- to the tonsil, the danger of the above mis- chief is considerably increased by a general spasm, which seems to aifect every part of the mouth. Hence this eminent surgeon used to employ, for the removal of diseased tonsils, an instrument, which w'as first in- vented for dividing cysts of the bladder. It consisted of a sharp-edged blade, which w T as included in a silver sheath. The latter had at its extremity a kind of notch, in which the gland, which was to be extirpated, W'as re- ceived. The rest of the instruments were similar to those commonly used. Desault proceeded as follows: 1. The patient being seated on a high chair, w ith his head supported on an assist- ant’s breast, he is to open his mouth very wide, and the lowmrjaw is to be kept thus depressed, by some solid body placed be- tween the teeth, and held there by an assist- ant. 2. The tongue is to be kept down with a broad spatula. 3. The surgeon is next to take hold of the tonsil with a double hook, w ith which he is to raise and draw it a little towards him. He is then to take the above cystitome, and put the tonsil in the notch, on a level w ith the place where the incision is intended to be made. 4. When the portion which is to be cut oft', is engaged in the notch, the operator is to draw the part towards him, so -as to stretch it, and press the instrument against it from below upward. The blade being next pushed across the notch, the necessary section is accomplished. When the division is not complete, which is particularly liable. to happen, when the diseased gland is of considerable magnitude, the blade is to be drawm back, and the section completed by applying the instrument to the wound, W’hiph it has already made. Sometimes even a third application may possibly be- come requisite. 5. The patient is to be directed to wash his mouth. Bichat states, that this plan of operating, adopted by Desault, is as simple and easy as the method above related, with the advantage of being safer. Such is the construction of the blade of the instrument, that when it slides across the notch, it presses against, and steadily fixes the parts which are to be d.vided ; an advantage which neither the knife nor scissors have, under the action of which the parts are quite moveable. Hence there is difficulty in cutting them. Wnen the introduction of the instrument from above downward is difficult, it is better to withdraw it ; and, alter turning the notch in the opposite di- rect ion, pass it from below upward. In general, however, the first of these methods is preferable, because the gland, when half cut through, cannot now fall back and db- struct the rima glottidis, so as to bring on danger of a sudden suffocation ; a circum- stance which Wiseman and Moscati saw happen. With a view of preventing this occurrence, Louis recommended the com- mon scalpel to be used, with its edge direct- ed upward, as has been advised for the above instrument ; which latter contrivance, however, being, according to Bichat’s ac- count, more easy and safe, merits the pre- ference. Besides the advantage of fixing the soft parts, which are to be cut, it has that of not contusing them, like most other instruments ot this nature, as, for instance, scissors. The oblique disposition of its blade enables it to divide parts, in the man- ner of a saw. This invention, as Bichat allows, is cer- tainly increasing the number of surgical in- struments ; a thing, w'hich all the best mo- dern surgeons endeavour to avoid But it is to be recollected, that this instrument is not exclusively applicable to any particular operation. It may be employed for cutting away the tonsils and uvula ; dividing mem- branous fraena in the rectum, vagina, and bladder; amputating lungous excrescen- ces, polypi of the nose, (if this mode of extirpating them were preferred) and va- rious tumours in general, which are deeply situated in different cavities of the body, where instruments introduced unguardedly might injure parts which should be avoided, or where the base of the tumour should be steadily fixed, when its division is to be ac- complished. The latter object cannot safely be rife, ted by scissors When the base ot t ie tumour is too large to be received in the notch, one part is first to be divided, and then another, till its whole thickness is cut through. In England, when a diseased tonsil is to be cut away, surgeons generally prefer a common scalpel rot/ 487 As a general practice, I consider, that the excision of an enlarged tonsil is a better practice than the extirpation of it with a li- guture, which also sometimes answers very well, and, perhaps, in children and timid patients may merit the preference. The chief objections to the ligature are. that its operation is rather tedious, sometimes pro- ductive of a great deal of irritation, and, on the whole, at least as painful as the knife. Moscati having once adopted Ibis plan, very severe pain and inflammation ensued; the difficulty of swallowing and breathing ) compelled him to amputate the tumour at the place where the ligature was applied, and all the bad symptoms immediately ceas- ed. Besides, when the ligature is used, there is no oozing of blood from the vessels, a circumstance which tends so much to di- minish the inflammation. The base of the ! swelling is also sometimes broader than its upper part, and does not admit of being properly surrounded with a ligature. And, when it has a narrow base, it can then be so easily removed with a scalpel, or with Desault’s instrument, and with so little pain, that one of the last modes is generally pre- ferable. The Hgature, however, has had its advo- cates. Heister recommends it, in certain cases ; Sharp praises it ; and others approve its use ; while the plans ot employing it have been as various as the inventive genius of the different partisans of the practice. Some make use of Levret’s double cannula, which is furnished with a silver wire noose, in which the tumour is to be engaged By twistingthe instrument, the diseased part be- comes constricted ; and this plan being repeated every day, the circulation is inter- cepted, and the gland mortifies, and sloughs away. Some, after putting the noose of a ligature over a kind of tenaculum, hook hold of the tonsil, push the ligature over the enlarged gland, which they tie, without having any means of increasing the con- striction afterward. Some employ Bello- que’s instrument for putting the ligature over the tonsil. Others require no instru- ment whatever for the purpose, and accom- plish the business with their fingers. Desault employed an instrument, which the French call un Serrc-ncnid, which is in fact, nothing more, than a long, narrow, round piece of silver, terminating at one end in a little ring, or hole, and, at the other, in a kind of groove or notch. The following was Desault’s method of extirpating the tonsils with a ligature. 1. The patient w T as seated on a high chair, I with his head held back, on an assistant’s ; breast; his mouth was opened very wide, his tongue depressed, and the diseased ton- sil taken hold of with a double hook. 2. The surgeon took the serre-noeud , in which a ligature had been passed, so as to | form a noose. The noose was put over the * handle of the hook, which was committed 1 to the charge of an assistant, and the noose then pushed over the tonsil, so as to embrace it completely i>. The surgeon now drew the ligature strongly towards him, and pushed forward the serre-noeud, so as to product the requisite constriction of the tumour. In general, the ligature was not made very tight the first day. 4. When the necessary constriction had been made, the double-hook was withdrawn, and the ligature tw isted round the notch, at the outward end of the instrument. 5 The next day, the gland became unu- sually large, in consequence of the impedi- ment to the return of the venous blood. The ligature was unfastened from the notch- ed end of the instrument and drawn more out, so as to increase the constriction, after which it was again twisted round the notch, I his plan w r as followed up t IS the tumour was detached, which usually happened on the fourth, or fifth day. Mr. Chevalier, a few years ago, described a particular mode of passing and securing the ligature. He passes a flat spear pointed hook behind the diseased tonsil, and its point is then pushed forward, so as to perfo- rate it through the middle of its base. The needle is then to be withdrawn, and an eye > probe, very much curved, and armed with, a long double ligature, may then be readily passed through the perforation, and brought out at tne mouth, the ligature divided, and one portion tied round the upper half of the tonsil, and the other round the lower. “ A single knot being first made upon one end of the thread, the end so knotted, is to* be brought forward upon the other, and to make a single noose upon itself including the other, and to be drawn tight upon it, close to the first knot. The free end of the thread is then to be passed” through a ring at the end of an instrument for the purpose, and ‘ beingthen held firm, and thering push- ed forward upon the knot, the loop, now formed, may be readily tightened, so as completely to strangulate the diseased part ; and in the same manner, it may be tighten- ed, from Jay to day, till the part is entirely detached.” (See Med. Chi'. Trans. I ol.3,p, 80, fyc.) The subject is more intelligible with the plate. In cases of angina, the tonsils are some- times suddenly attacked with such a degree of swelling, that respiration is dangerously obstructed. This c^se is analogous to the occasional enormous inflammatory swelling of the tongue, and, if it resist venesection and leeches, the most prompt mode of re- lief is that of making several deep scarifi- cations with a knife in the part. Many cases, confirming the good effects of this practice, have been seen by Langenbeck, (See JVeue Bibl. B. 2, p. 492, fyc.) TOPHUS. A swelling, w r hich particular- ly affects a bone, or the periosteum. See JYode. TORTICOLLIS, (from torqueo , to Iwdst ; and collvm, the neck.) The wry-neck. See Wry-neck. *TOURl\IQU£T. ( French , from lourner, to turn.) An instrument used for stopping the flow of blood into a limb, until some reqm- I017KNIQUET. site operation has been performed, or some more permanent plans of checking hemor- rhage have been put in practice. The old surgeons used to surround the limb with a band, with which they made such a degree of constriction, that the cir- culation was quite stopped. They also be- lieved, that the pressure of the band was ad- vantageous, in benumbing the limb, and moderating the pain of operations. The violent pain and contusion, how- ever, which such a tourniquet occasioned, being frequently followed by mortification and abscesses, surgeons found it necessary to devise some other method of checking hemorrhage. The application of the circu- lar band was first improved, so that it caused less pain, and less mischief to the skin. 'I he limb was surrounded with a very thick com- press, over which the band was placed. Two small sticks were nest put under the band ; one on the inside, the other on the outside of the limb ; and they were twisted till the band was rendered sufficiently tight. It is in this manner, says Dionis, in his Trait6 d- Operations, that carriers tighten the cords which fasten the bales of goods in their carts. A French surgeon, named Morel, is said to have maJe this first im provement in the application of tourni- quets. J. L. Petit, in 1718, presented to the Aca- demy of Sciences a tourniquet of his own invention, which was much more perfect than any previously contrived. It consists of two pieces of wood, one of which is su- perior, the other inferior. The inferior piece is about four inches and a half long, and nearly two broad. Its under surface is somewhat concave, while its upper one is a Tittle convex, and the ends are hollowed out. From its middle part rises a round eminence, about seven lines high, and eight and a half broad. The superior piece is almost the same as the inferior one, but rather shorter. The eminence, which as- cends from its middle part, is six lines high, and an inch and a half in diameter. This eminence is hollow within, and calculated to receive a w T ooden screw, the top of which is a sort of button for turning the screw. The grooves of Petit s screw were about four, or live, and each of them four lines in diameter, in order that a half turn might produce the necessary elfect. Lastly, all the pieces of the instrument were fastened together with an iron pin, which went through the middle of the two pieces of wood, and through the w hole length of the screw. This iron pin was riveted under the inferior piece, and at the top of the button, in such a manner, however, that the screw was capable of turning on it, as on a pivot. In order to apply this tourniquet, the limb is to be surrounded with a double strap, about four finger-breadths wide, and made of chamois leather, which is the softest ma- terial that can be used. To one end of the strap a double little cushion is fastened, of the same length and breadth as the lower piece of the tourniquet. A narrow com- press, or cylindrical pad, is also requisite- for the purpose of compressing the track of the vessels. This compress consists of a very firm roll of linen, covered with cha- mois leather. The ends of a piece of tape are sewed to the outer part of the pad, and thus the tape leaves a passage for the lea- ther strap. By this artifice, the pad can be moved to any situation on the strap, as the y bulk of the limb may require. . The middle of the tape is to be fastened to the outside of the leather strap. The cylindrical com- press, or pad, is to be put over the course of the vessels. The double cushion is to be placed on the opposite side of the member, while the leather strap is to surround the limb. All the different pieces of the appa- ratus are next to be retained by means of the tape, which is to be tied at the side of the cushion. The tourniquet is now r to be put over the cushion, on that side of the limb which is furthest from the track of the large vessels, and is to be fastened in this situation with a double band, that has a hole in it for the re- ception of the upper part of the screw. In order to make the proper compression, the screw is to be half turned round, from the right to the left. The upper piece of the tourniquet becoming now further from the lower one, the double band draws the pad, and presses it against the vessels, so as to make the due degree of compression. The following are the advantages, attend- ing the use of Petit’s tourniquet : 1. It com- presses the lateral parts of the limb less than the tourniquet previously in use. 2. It requires the aid of no assistant, either to hold, tighten, or loosen it. 3. The operator is able of himself to stop the flow of blood in the artery, by means of the screw. 4. When there is any danger of hemorrhage after an operation, this kind of tourniquet may be left on the limb, and, in case of the bleeding coming on, the patient, if no one be at hand, can tighten the instrument him self, as much as is necessary. 5. The con-’ striction, which this tourniquet produces, does not create any danger of mortification, because it does not altogether stop the flow of blood through the collateral arteries. The tourniquet here described is certainly very complex, when compared with that, which is used by the best modern practi- tioners; but, still it is the original of the latter, and both are constructed on the same principles. All the pieces of modern tour- niquets are kept connected together, and in- stead of two pieces of w r ood, used by Petit, there is contrived a brass bridge, which is capable of being elevated, or depressed, by means of a screw, made of the same metal Over this bridge a very strong band pro- ceeds, and by passing under tw o little roll- ers, at each end of the bridge, it .always re- mains connected with the instrument. A convex firm pad is sewed to the band, and put immediately over the artery, where the instrument is applied. There are no cush- ions for the opposite side of the limb under the screw ; but. a thick piece of leather TREPHINE. 4S9 through which the baud proceeds in two places, is always situated under the lower surface of the brass, and serves to prevent any bad effects of its pressure. It is usual also for the surgeon to fold some rag, and to put it in this situation, at the time of ap- plying the instrument. (See Hemorrhage.) The interruption of the circulation in parts of the body by the tourniquet, has been tried as a means of relieving diseases. (See G. Kellie, Obs. on the Medical Effects of Com- pression by the Tourniquet, 8vq. Edinb. 1797.) TRACHEA, Wounds of. See Throat. TRACHEOTOMY. (from r^ua, the windpipe, and re/uvee, to cut.) The opera- tion of cutting an openinginto the windpipe for various surgical purposes. See Bron- chotomy. TREPAN, (from rpi >7r*u, to perforate.) Trepanum ; Terebellum ; Modiolus. A cir- cular saw, by means of which the skull is perforated in the operation called trepan- ning, or a circular portion of any bone may- be sawn out. It bears a considerable re- semblance to the well-known instrument named a wimble, and is worked in the same manner. Formerly, the saw was sometimes made of a conical shape ; (see Abapliston ) but this construction rendered the action of the instrument difficult. In this country, the trepan is now superseded by the instru- ment called a trephine, which has a different handle, and is not worked in the same way. On the continent, however, the trepan still has the preference. TREPHINE. The instrument now com- monly preferred for perforatingthe cranium, for purposes which I shall presently explain. It consists of a simple cylindrical saw, with a handle placed transversely, like that of a gimlet ; and, from the centre of the circle, which the teeth of the saw describe, a sharp little perforator projects, named the centre- pin. The upper part of the centre-pin is made to screw in a corresponding hole at the inside of the top of the saw, and is ca- pable of being taken out, or put in, at the surgeon’s option, by means of a little key for the purpose. Its use is to fix the tre- phine, when it is first applied, that is, before the teeth of the instrument have made a sufficient circular groove, in w hich they can steadily work. When this has been ac- complished, the centre-pin must always be removed; because now it is not only not needed, but if left, it would retard the pro- gress of the operation, and inevitably wound the dura mater and brain, when the teeth of the saw had cut to a certain depth through the cranium. My trephines have their centre-pins contrived to slide up, or dow n, and to lie fixed in either position by turning a little screw. This method seems to me both ingenious and convenient. The cylindrical part of the trephine is often termed the crown of the instrument. The surgeon should have at least two or three cylindrical saws of various sizes ; for it is always a commendable rule, never to saw away any more of the cranium than is abso- lutely requisite for the accomplishment of Vo l. II some rational objpct. There is no occasion, however, for having any more than one han- dle, which maybe made to screw on any of the saws. Trephines are also occasionally applied to other bones, besides those of the cranium. In the articles Antrum , Caries, Exostosis , Fractures of the Sternum, JYecrosis, Spina Ventosa, other cases are mentioned, in which the employment of these instruments some- times becomes proper. It is not always desirable to remove a com- plete circular portion of the cranium, the taking away a piece of smaller size, and of a different shape, being frequently much more advantageous. Some surgeons, i understand, who object to removing any unnecessary- quantity of the cranium, have been in the habit of employing a trephine, terminating only in a semi-circular, instead of a circular saw, by which means they can often cut across the base of a depressed portion of the skull, and take it away, without any occasion for removing also a circular piece of bone. An i -ftrument of the latter kind may cer- tainly be sometimes useful. The saws, however, which Mr. Hey has described, should constantly be kept in every case of trephining instruments. This prac- tical writer remarks, that “the purposes for which any portion of the cranium is remo- ved, are, to enable the surgeon to extract broken Iragments of bone, to elevate what is depressed, and to afford a proper issue to blood or matter that is, or may be, confi- ned, kc. “ When a broken fragment of bone is driven beneath the sound contiguous part of the cranium, it frequently happens, that the extraction cannot be executed without remo- ving some of the unbroken part, under which the fragment is depressed. This might gene- rally be effected with very little loss of sound bone, if a narrow portion of that which lies over the broken fragment could be removed. But such a portion cannot be removed with the trephine. This instrument can only saw out a circular piece. And as, in executing this, the central pin of the saw must be placed upon the uninjured bone, it is evident that a portion of the sound bone, greater than half the area of the trephine, must be removed at every operation. When the broken and depressed fragment is large, a repeated ap- plication of the trephine is often necessary, and a great destruction of sound bone must be (he consequence. “ When the injury consists merely of a fissure with depression, a small enlargement of the fissure would enable the surgeon to introduce the point of the elevator, so as to raise the depressed bone. But a small en largement of the fissure cannot be made with the trephine. When it is necessary to apply the elevator to different parts of the de- pressed bone, a great deal of the sound cra- nium must be removed, where a very narow aperture would have been sufficient. li The same reasoning will apply to the case of openings, made for the purpose of I TREPHINE. giving a discharge to extravas&led blood or matter. “ If a saw could be contrived which might be worked with safety in a straight, or gently curvilineal direction, it would be a great ac- quisition to the practical surgeon. Such a saw I can now with confidence recommend, after a trial of twenty years, during which time I have rarely used the trephine in frac- tures of the skull. Its use has been adopted by my colleagues at the General Infirmary in Leeds ; and will be adopted, I hope, by every surgeon who has once made trial of it.” Mr. Hey next informs us, that the in- strument was first shown to him by Dr. Cockell, of Pontefract ; but that there is a saw formed on the same principle in Scul- tetus’s Armamentarium Chirurgicum. The saws alluded to are very short ones, fixed at the end of a longish straight handle ; theTr edges are made eiihe> straight or semicircular. The latter construction qualifies the instrument for cutting in a curvilineal direction, which is often proper. The edge of the saw should always be made a little thicker than the rest of the blade, by which means it will work in the groove, which is cut with more faci- lity. Saws made on the principle just described, are also oi infinite use in cutting away dis- eased portions of other bones besides the skull, exostoses, &c. In cases of necrosis, when a dead part of a bone is quite wedged in the substance of the surrounding new bony matter, Mr. Hey’s saws may often be advantageously employed tor cutting away the parts, which mechanically prevent the detachment of the dead pieces. The saws invented by Mr. Machell and Professor Graefe, are also highly ingenious, and parti- cularly merit attention, when there is very little room for the working of the instrument, and the bone to be cut lies rather deep. They are wheel-like saws, turned by ma- chinery. Besides trephines of various sizes, and the saws just now noticed, the surgeon should also take care to have in his case of trephi- ning instruments a little brush for occasion- ally cleansing away the particles of bone from the teeth of the saw in the progress of the operation 3 a pair of forceps for extract- ing the round piece of bone after it has been detached by the saw ; a lenticular for remo- ving any inequalities which may present themselves round tlfte sawn edge of the cra- nium after the circular piece is taken out j a raspatory for the same purpose, and also for scraping the bone in order to see whether it will bleed, which is a eircumsta'gce in some cases very important to be attended to j (see Head , Injuries of ,*) a largish common scalpel for dividing the scalp, &i.c. ; and some elevators for raising depressed pieces of bone. The common elevator is now generally used by all the best English surgeons ; but several others have been proposed, as, for instance, the tripod elevator ; and another invented by J. L. Petit, and afterward im- proved by M. Louis. Before beginning the description of Che operation, I think it highly proper to remind ttie reader of what has been so forcibly dwelt upon in the article. Head, Injuries of ’ — that, generally, the removal of pressure off the brain, w hich pressure must also actually oc casion dangerous symptoms, can form the only true and vindicate reason for employ- ing the trephine, or sawing away any portion of the skull. There are very few exceptions to this remark : it may, indeed, be now and then proper to saw away the bony edges- around some fungous excrescences, which grow from the dura mater, and make their way outward, by occasioning ari absorption of the part of the skull immediately over them. (See Dura Mater.) Ii may also be sometimes proper to saw out diseased por- tions of the skull, though, it must lie confess ed, that in general their separation should bo left to time and nature. In the records of surgery, innumerable facts may be consulted, where the prudent and judicious employment of ihe trepan has effected wonderful cures, and been the only thing by which, the patients’ lives could pos sibly have been saved. Ihe benefit which the operation brings about, is also sometimes so sudden and >stouishirig, that in no in- stance does the interposition of the surgical art display itself to greater advantage. The immediate restoration of sight by the de pre-siun, or extraction of an opaque sub- stance from (he eye, is not more beautiful and striking, than the instantaneous conitnu- ideation of the intellectual faculties, and of the powers of speech, of feeling, &.c. toge- ther with voluntary motion, to a person ly- ing in an apparently lifeless state from an in- jury of the head. The utility of the trepan is occasionally manifested even in this de- gree. In the valuable essay of Mr. Aberne- thy on injuries of the head, a case may be seen, in which the patient, who had been in a condition almost bereft of animation, rose up and spoke the instant the exlravasated blood was removed from the surface of the brain. And among the wounded at the bat- tle of Waterloo, there was a soldier of the 44th regiment, whose case is of equal inte- rest. He had been struck by a musket-ball on the right parietal bone, which was expo- sed, but had no appearance of being fractu- red. As however the symptoms of com- pression were urgent, and (he patient w as in nearly a lifeless state, I conceived it right to apply the trephine to Ihe part on which the violence had acted. I had not sawn long before the external t * ble came away in the hollow 7 of the trephine, leaving ihe inner table behind, which was not only splintered but driven at one point more than half an inch into the membranes and substance of the brain. No sooner were the fragments taken out with a pair of forceps, than the man instantly sat up in his bed, looked round , and began to speak with the utmost rationali- ty. It is a most extraordinary fact, that this patient got up and dressed himself (he same day, without leave from the medical officers, and never had a bad symptom afterward. TREPHINE. ‘191 Immediately the operation was finished, the temporal arteries were opened, and some purgative medieines exhibited. In a case of fungus of the dura mater, with diseased bone, mentioned by Schmuck er, the trepan was applied eleven times in less than a month, and the operation U3ed to cause so little indisposition, that the patient hardly ever required to go to bed afterward, and, on one occasion, actually went to mar- ket an hour after its performance. ( Wahrneh- w 1 tnvngen, D. I,;?. 456.) Let not the young surgeon, however, draw from these dagzling cases of success an im- moderate solicitude to perform the opera- tion ; for it should never be undertaken but in the most pressing circumstances, and when the symptoms unequivocally show that a dangerous degree of pressure on the brain exists. 1 recollect an unfortunate ex- ample, in which the late Mr. Ranisden, of St. Bartholomew’s Hospital, ventured to saw out a portion of the frontal bone for a mere tong- continued pain in the part : the patient was attacked with inflammation of the dura ma- ter, and perished in three or four days. We may therefore conclude, that the operation is not itself exempt from danger j and it is certain, that it ought never to be resolved on without deep cons deration. “ Gravis tam&n satis est operatio , ut nunquam , nisi in- dicaliones sujjwienles admit, instil ui debet ” (Callisen Syst. Chir. Hodiern. Tom. I, p. 658.) The trepan, or trephine, is never neces- sary in injuries of the head, except for the purpose of relieving the brain from pressure. Such pressure may be caused by a depressed portion of the cranium, or it may be pro- duced by an extravasation of blood, or the lodgment of matter, betwixt the skull and the dura mater. The chief danger of con- cussion, when the accident is not directly or soon fatal from the disorganization and mischief done to the brain, depends upon > the consequent inflammation of this organ, and therefore can be little likely to be be- nefited by the use of the trepan. If the operation becomes proper in such a case, it is when an abscess has formed under the cranium, and when the confined matter it- self creates bad symptoms by its pressure on the brain. This state of things, how- ever, cannot come on till after the inflam- mation of the brain and its membranes has prevailed a certain time, and it is always accompanied with a detachment of the pe- ricranium and a puffy tumour of the scalp or, if there be a wound of the latter part’ immediately over the abscess, the lips of the injury suddenly acquire an unfavour- able appearance, arid lose their vermilion „ colour. I he patient has also had much preceding febrile disorder, pain and tension over the whole head, redness and turges- cence of the eyes, and generally more or less delirium. When the matter is forming, there are usually some rigours, and, as soon as it is formed, the patient falls into a co- matose state, and paralytic symptoms show { themselves. Here the urgency for the i prompt application of the trephine is very great, and the patient’s chance of living is almost essentially connected with the imme- diate performance of the operation. This important case has been particularly dwelt upon in the writings of Mr. Pott. In the article, Head, Injuries of, I have laid down the most remarkablasymptoms of concussion, and compression of the brain, a subject which every surgeon should study with earnest attention, before he ever pre- sumes to employ the trepan. For, some- times these accidents are extremely difficult to be discriminated ; sometimes they exist together in the same individual ; a compli- cation which is peculiarly embarrassing; and in every instance where the symptoms are those of concussion, the operation, so far from being indicated, would be a step of all others the most likely to do harm, by in- creasing the irritation and inflammation of the brain and its membranes. A fall upon the back, or upon the head, occasions a di- rect concussion of the brain, and the shock not being materially weakened by the in- tervention of any yielding elastic structure, is the more dangerous. When«a person has fallen from a certain height, and pitched on his head, his back, the buttocks, the knees, or even the soles of the feet; when he has been instantly deprived of his senses, and then by degrees recovered them and come to himself again ; the fact of his having suf- fered cory^ussion of the brain is clear and indisputable. Concussion has likewise taki n place, though in a slighter degree, when the patient has been only stunned by the fall, and experienced a sensation of sparks. But a multitude of degrees separate this feeble concussion from that in which the substance 'of die brain is instantaneously disorganized, so that (lie patient has not the possibility of recovery. The symptoms of concussion of the brain are attended with coma, and the compres- sion of this organ by an extravasation is also accompanied with lethargic heaviness. How then is the surgeon to ascertain, whether the comatose disorder arises from one or the other of these aflectious ? Here in order to avoid repetitions, I beg leave to refer to the observations already made in the article quoted above. But there is one criterion of such first-rate importance, that it may prevent innumerable fatal mis- takes, and, indeed, without the continual re- collection of it, no man ought to be rash enough to interfere with this dark and ab- struse part of surgery. On (bis account, f shall mention it here, notwithstanding it has been already noticed elsewhere. If the pa- tient is knocked down and stunned directly by the blow, and remains in a state of insen- sibility, these primary symptoms are ascri- babie to the concussion. On the contrary, when the coma and loss of sense do not take place till an hour or two alter the blow, they are to be imputed to an extrava- sation. The shock given to the brain by concus- sion must, like every other impulse comma- TREPHINE. 192 nicated, continue to diminish until it ceases altogether. If at the very time of the blow, the shock has not been forcible enough to produce alarming symptoms, such symptoms will not afterward come on when their cause is weakened. Hence the reason why com- pression can be distinguished from concus- sion of the brain, when there has been an interval of sense between the receipt of the blow and the occurrence of the bad symp- toms. But the distinction of the symptoms into primary and consecutive cannot be made when concussion and extravasation exist together. Having made these few remarks on con- cussion arid compression of the brain, re- marks which seemed necessary before I entered into a description of the operation of the trepan, I shall next premise some observations relative to contusions and fractures of the skulj, cases on which the most erroneous opinions have been enter- tained. It is true, that l have in another place (see Head , Injuries of ) considered the subject; but it may be better to recapitulate certain points here, because they have such immediate # connexion with the application of the trephine. Contusions of the head not unfrequently occasion a small kind of tumour which is soft in the centre, but hard and resisting at the circumference, especially when the vio- lence has been considerable. Now the ease with which the centre or seat of the extra- vasated fluid admits of being depressed, while the circumference remains hard and elevated, is extremely apt to give rise to the belief, that a fracture with depression has happened. The true nature of this accident was first clearly explained by J. L. Petit, and since his time the proper cautions not to fall into a mistake concerning it, have been laid down by tbe generality of surgical \v iters. Often nothing is more obscure, than the diagnosis of fractures of the craniu m : their existence indeed can only be made out with certainty, when they can be felt or seen. Thus a fracture of the skull, attended with a wound of the scalp, and exposure of the bone, shows itself in the form of a fissure more or less wide and extensive, and taking various directions. The accident may also be known by the touch even when the soft parts continue entire, particularly if the frac- t ire is accompanied with splinters, or the edges of the fissure are materially separated. When there are many splinters entirely detached, a crepitus will likewise serve to explain the nature of the accident; but unassisted by these symptoms, imparted to him by the sight, the hearing, or the touch, the prac- titioner cannot at once offer a decided opinion as to whether a fracture exists or not. In order to procure more positive infor- mation, would it be right and judicious to make several incisions and uncover the bone ? But here tbe surgeon would be em- barrassed in the very commencement of his proceedings : for how would he be able to judge where the kite should be applied:' Why also should he resort to an useless and painful operation, which (to say the best of it) could only render the patient’s cure more distant ? The symptoms indicating compression of the brain, can alone justify an examination of the fracture. These symptoms also must be urgent and alarming ; for when they pre- vail in a slight degree, bleeding and evacua- tions promise more benefit than any opera- tion on the skull, and consequently all exa- mination of the part supposed to be broken, must be unnecessary. The precept too commonly given, to cut through the scalp for the purpose of bringing tbe fracture into view, will no longer be matter of surprise, when it is known, that among some sur geons, the operation of the trepan is a thing of course in all fractures of the cranium. Even w hen the cranium has been denu- ded, so that the sight can convey due infor- mation respecting the solution of conti- nuity in the bone, care must be taken not to be deceived by a suture, or by the groove of a vessel. In cases of doubt, a modern sur- gical author advises us to scrape the outside of the bone ; and he tells us, that if after the removal of the external scale, the fissure yet appear, and a thread of blood be seen at its outer part, no doubt exists of its being a real fissure. As however making this examina- tion can answer no purpose, except with a view to determining the place where the trepan should be applied, I cannot recom- mend the plan, except where the sj’rnptoms are such as to render this information de- sirable. On the contrary, it appears to me, that all examinations of the bone, made seemingly from mere curiosity, and without any true surgical object, should be depreca- ted as rash and hurtful. The danger of fractures of the skull does not depend upon tbe simple solution of con- tinuity : it bears altogether a relation to the concussion and compression of the brain, with which the injury of the bone may be complicated. The pressure which is caused by depressed splinters of bone, is less alarm- ing, inasmuch as the cause of the compres- sion is easy of removal. The pressure arising from extravasated fluid is far more serious, in consequence of the difficulty of ascertaining positively the existence and precise situation of such extravasation. The seat of the extravasation is sometimes between the skull and the dura mater, which has been detached from the bone. More frequently it occurs either between the dura mater and tunica arachnoides ; in the sub- stance of tbe brain ; or else in the ventri- cles. The quantity of extravasnted fluid is generally less in those extravasations, which are situated between tbe dura mater and the skull. The extravasations which are formed in the substance of the brain itself, are not only more considerable, but also, as they mostly depend upon concussion, are more alarming than effusions on the surface of the dura mater. It is indeed extremely difficult, if not impossible, to ascertain the situation of the extravasated fluid. In such cases the trepan is likewise of no use ; while concus- sion, when so violent as to produce internal extravasation, is invariably fatal. In extrava- sations between the dura mater and the skull, which are almost the only cases of the kind to which surgery can administer relief, when the effused fluid lies under a part of the skull accessible to the trepan, the extravasated fluid is almost always small in quantity. The danger, however, is not the less : ten or twelve drops of fluid are sometimes enough to produce a fatal compression. When the extravasation Tias happened in the substance of the brain, the compression is far more perilous : in short, it may be said to prove with very few exceptions, certainly mortal. The danger is not so great, when the extra- vasation is situated between the skull and dura mater. The lethargy, the degrees of which in- crease from mere drowsiness into the most perfect coma ; and the paralysis of the op- posite side of the body to the seat of the ex- travasation ; are the characteristic symptoms of this accident in cases of injury of the head. Having explained elsewhere (see Head, Injuries of) some other symptoms, such as stertorous respiration, dilated pupils, &c. which usually indicate pressure on the brain, it is unnecessary here to dwell upon them. The subsequent increase of the coma, and paralytic affections, and the gradual augmentation of their intensity, serve to render these symptoms distinguishable from others, which are suddenly brought on by concussion. But there are instances, as every man of experience knows, in which concus- sion ruptures the blood-vessels, and produces an extravasation of blood. In this circum- stance, it is obvious that the symptoms of compression are blended with those of con- cussion. The symptoms proceeding from the latter cause always diminish in propor- tion to the time, which has elapsed from the moment of the injury ; w'hile those of com- pression succeed, and on the contrary, in- crease in intensity, in proportion as the quantity of extravasated fluid becomes more considerable. Notwithstanding these dis- tinctions, however, it must be acknowledged, tbat there are many cases in which the sur- geon is obliged to remain in doubt, with re- gard to the particular cause of the symptoms. This indecision is the more embarrassing, because the operation of the trepan is neces- sary in cases of extravasation, but useless in those of concussion. Even when extrava- sation is known to exist, the practitioner re- quires more information ; for he ought to Know the precise situation of the effused fluid. It is true, indeed, that paralysis of one side of the body generally indicates the pressure to be upon the opposite hemisphere of the brain. But what surgeon would ven- ture to follow the practice advised by Van Swieten,and apply to the suspected side o£ the head three crowns of the trepan ? Possi- bly not one of them might fall on the situa- tion of the extravasated fluid. When the - c kul! is broken, tbe extravasation exist? on 493 the same side as the fracture. When it is the effect of concussion, or when the breach of continuity in the skull is what is termed a counter-fissure ; the effusion is generally on the side of the head most remote from tbe blow. If the pressure is caused by a detach- ment of the internal table of the skull, the nature of the case cannot be ascertained be- fore tbe operation of the trepan has been performed on the part of the skull, upon which the violence has acted. When there are two extravasations ; one depending upon a fracture, and situated immediately under it, between the dura mater and the skull ; the other arising from concussion, and situa- ted at some point directly opposite, either between the dura mater and tunica arach- noides, or within the substance of the brain itself; paralysis may occur on tbe same side as the fracture, and hence it may be inferred, that the palsy does not always take place on the side opposite to the extravasation. But, says Richerand, an examination of the body quickly proves, that the case does not devi- ate from the common rule. The extravasa- tion produced by concussion, being almost invariably more considerable than that caused by a fracture, accounts for the ex- tension of the palsy to the same side of the body. Sometimes the side which is not pa- ralytic, is effected with convulsions ; the pulse is full and hard ; and the respiration stertorous ; in short, the symptoms are analo- gous to those caused by apoplexy. The evacuating plan, recommended for the treatment of concussion, (see Head , Injuries of) is all that can be done, when every thing is uncertain relative to the situa- tion of the extravasation. It is all that can be done in those frequent instances, where the effusion has taken place in the substance of the brain, so that it cannot possibly be voided. The trepan then is indicated only when there is an extravasation between the dura mater and the bone, the fracture being situated at a part of tbe skull accessible to instruments, and not at the base. We will not here dwell upon the doubtful example, w here the fluid lies between the dura mater and the arachnoides. But, are the cases, which have just been described, as frequent as they are supposed to be ? Cannot the effused blood be sometimes discharged through the interspaces of the broken pieces of bone ? Is the trepan usually necessarv for the relief of injuries of the head, as Quesnay, Pott, and the members of the French Academy of Surgery maintained ? Many of the best surgeons now think not — The operation is often useless, and some- times dangerous. I believe that it should be limited to a small number of cases, in which not only the existence and situation of the pressure are known, but in which the symptoms, arising from this cause, are ur- gent and dangerous, and the pressure can be removed by no other means. Richerand contends, that extravasations between the skull and the dura mater, so considerable as to produce compression of the brain, and render the trepan necfessarv. TREPHINE. 494 are much less common than many surgeons think. Even when they do occur, the dura mater is always detached to a certain extent, and, according to this writer, if the bone is much broken, the interspaces of the frag- ments are quite sufficient for the evacuation of the effused blood. The following case is quoted in proof of this observation. A wo- man injured her head by falling from a height of fifteen feet. The fracture reached the whole breadth of the skull, so that when the os frontis was taken hold of with one hand, and the os occipitis with the other, the two halves of the cranium admitted of being manifestly moved and separated. Blood issued from the fissure, the edges of which were kept apart by a small wedge of wood in such a manner, that the pulsations of the brain were visible. On the sixth day, as nothing was discharged from the fissure, the bit of wood w'as removed, and on the fifty-second the wound had completely heal- ed without any exfoliations. On the seventy- second, the patient was discharged from the H6tel-Dieu, perfectly cured. ( JYosogr . Chir. T. 2, p. 292, Edit. 3.) Thus we see, that the trepan is not always necessary in injuries of the head with frac- ture of the skull, notwithstanding there may be some degree of bleeding from the edges of the bone. This doctrine is very different from what is taught in t|ie memoirs of M. Quesnay in the first volume of those of the French Academy of Surgery. Desault in the last years of his practice abandoned the operation of the trepan altogether. It had been remarked for many years, that, in the H6tel-Dieu, this operation was almost always unsuccessful ; a circumstance, which once excited a suspicion, that the foul air of the wards of that establishment might have a share in bringing on the unfavourable event. I shall not here expatiate on the bad effect of the atmospheric air on the membranes of the brain; a thing, of which B. Bell seems to have convinced Richerand. When the skull is fractured by a blow', or fall, and the case is a simple fissure, the trepan ought to be applied upon the solu- tion of continuity, if the symptoms indicate a dangerous degree of pressure on the brain, and the edges of the fracture are not sufficiently separated to let the extravasated lluid es- cape. When the detached portions of bone are depressed, so as to compress the brain, the operation is still requisite, if they cannot be elevated by other means. But Richerand maintains, that a positive indication for tre- panning is not frequent, either because it is difficult to judge of the existence and situa- tion of extravasations, or because extrava- sated fluids readily escape through the in- terspaces of the fragments, when there is a splintered fracture. Such facility is also increased, when one of the portions of broken bone is totally detached, so that it can be removed, leaving an aperture equi- valent to what would be produced by the , application of the trepan. When the operation is determined on, it is more convenient to have the head sha- ved : indeed, this is often done immediately the surgeon is called, in order that he may have abetter opportunity of seeing what parts of the scalp have been struck ; for it Is in such situations that he has most reason to apprehend fractures of the bone, or extra- vasations beneath it. If, however, the violence has occasioned a large wound, or laceration of the scalp, the practitioner, knowing where the force has been applied, is frequently content with having a little of the hair shaved off the parts surround- ing the injury. All that need be said on this subject is, that it is always better to have enough of the hair taken away, to afford the surgeon an uninterrupted oppor- tunity of examining the scalp freely, and doing whatever may be necessary. The loss of a little hair is of very little consequence, while the concealment of the seat of a de- pressed fracture, or extravasation, might lead to fatal consequences. When the propriety and necessity of tre- phining are fully indicated, provided the wound, or laceration of the scalp, should not have exposed a sufficient surface of the bone for the application of the crown of the trephine, an adequate dilatation of such wound ought immediately to be made. If, in the situation of the blow, there should only be a contusion, or a lump, unattended with any wound, a division of this part of the scalp is to be made by carrying the knife quite down to the bone. In those cases, in which the swelling occasioned by the violence is considerable, and attended with the sensation of a crepitus ; as well as in other instances, in which there is only a contusion, under which a fracture and dis- placed pieces of bone may be felt ; the scalp must be divided in the same manner, only with greater caution, lest the point of the knife should insinuate itself through the fracture, and do mischief to the dura mater and brain. Authors recommend the shape of the in- cision to be different according to the kind of fracture, and the parts of the head, on which the violence has operated. When the whole extent of the injury can be brought into view, by means oi an incision, having the form of a letter T, the surgeon should be content with such a division ; but if this be not sufficient, he may give it a crucial shape. When the trephine is to be applied to the squamous part of the temporal bone, we are recommended to make the incision as much as possible, in shape of the letter V, the branches of which are to be upward, and the angle downward, in order that as little as possible of the temporal muscle may be cut, and that the division ot its fibres may be avoided as far as it is in our power. Having divided the scalp, the next object Is to reflect it ; but no man would be w ar- ranted in cutting any part of it away, al- though such practice is advised by Pott and many other eminent writers. 1 he purposes of the operation do nol require any removal TREPHINE. 490 ot this kind ) and the method would leave a wound, which would be long in healing, and when healed, never exempt from de- formity. In short ,4he reflected flaps ot the scalp are capable of adhering to the parts, on which they are laid after the operation, and consequently ought never to be wan- tonly cut away. The scalp being reflected, authors nejit advise us to scrape aw*ay the pericranium, either w ith the knife, or the raspatory. Per- haps this measure may be considered as one, which does neither much harm nor much good. The design is to facilitate the application of the trephine to the bone. How r ever, the teeth of a proper instrument, in good order, will not be impeded by the slender periosteum ; and scraping this mem- brane away from parts of the skull, which are not to be removed, must be conducive to exfoliations. Sometimes the bleeding from branches of the temporal, or occipital artery, is so co- pious, that the bone cannot be very conveni- ently perforated before the hemorrhage is sup- pressed. If it be prudent to wait a little, and the case (as it generally does) should be likely to be benefited by the evacuation of blood, it is as w r ell to let the bleeding con- tinue for a certain time. The surgeon may then just direct an assistant to put the end of one of his fingers on the mouth of the vessel, and proceed in the operation. ll> some cases the bleeding might be so trou- blesome, that it would be better to tie the artery at once. All parts of the cranium do not admit of being trephined wdth equal convenience and safety. It has usually been set dow'n by surgical authors, that the trephine cannot be applied below r the transverse ridge of the os occipitis. There are some cases, how r - ever, which prove that such an operation may be safely done, and that we ought not in urgent circumstances, to be afraid of di- viding the trapezius and complexus muscles, in order to be enabled to apply the trephine to the bone. (See Hutchison's Casein Med. Chir. Trans. Vol. 2, p. 104, fyc.) The majority of writefs also forbid the application of the trephine to the frontal sinuses, in consequence of the indeterminate depth of these cavities, and the apprehen- sion of incurable fistulas. Howrever, Larrey has deviated from this precept in several instances, and his practice confirms the statement of Mr. C. Bell, that, by opening the frontal sinus with a large trephine, and then using a small one, the internal parietes of this cavity may be trephined with perfect safety, and no risk of injuring the dura mater with the saw. (See Larrey' s Mem. de Chirurgie Militaire, T. 2 ,p. 135 — 138, T. 4.) Writers also caution us not to apply the trephine to the anterior inferior angle of the parietal bone, in consequence of the middle artery of the dura mater lying un- der it, generally in a groo.ve of the bone, and occasionally in a canal in its very sub- stance. In the latter circumstance, this portion of the parietal bone could not pos- sibly be taken away, without wounding the vossel. However, notwithstanding this ad- vice, which has been unthinkingly banded down by one writer to another, from genera- tion to generation, I very much question the soundness of the doctrine. We undoubtedly ought to avoid trephining this part of the cra- nium, when w e can prudently do so. But the causes demanding this operation are ahvays so urgent, that the patient’s sole chance of existence depends on their cjuiek removal. Hence, wrnre there pressure on the brain, either from a depressed portion of bone, from blood, or matter, and such pressure could not be removed without trephining the anterior inferior angle of the parietal bone, w r hat operator would be afraid of do- ing so ? Besides, the fear of the hemor- rhage has been very, unfounded ; for the lodgment of the artery? :i a bony furrow, or canal, which authors have pointed out as rendering the suppression of the hemorrhage more difficult, is a mere visionary idea, as it is well known, that a little plug of lint pushed into the orifice of a vessel so situa- ted, will ahvays stop the bleeding, with as much certainty and ease as can 'possibly be imagined. The foregoing suggestion was made in the early editions of my w'orks, and I now’ see the safety of the practice has-been confirm- ed. “ I have also applied the trepan (says Larrey) over the track of the spheno-soi- *nous artery, at the inferior anterior angteof the parietal bone. The artery w^as divided - but I stopped the hemorrhage almost imme- diately, by applying an iron probe red-hot.” (Mem,, de Chir. Militaire, T. 2, p. 138.) Writers, until very lately, also prohibited us from trephining over any of the sutures, and especially over the sagittal suture, be- neath which the longitudinal sinus is situa- ted. The fear of the dura mater being in- jured, and of this vessel being- wounded, w r as the reason for the advice. With regard to the sutures in general, the trephine may be applied to them, as well as to any other part ; and as for the sagittal suture, many facts confirm the propriety of not being de- terred even by it, though situated immedi- ately over the longitudinal sinus. Jt is to be remembered, also, that the dura mater, in cases of extravasated blood and matter, beneath the cranium, is detached by the intervention of such fluids from the inner table. By means of a perforation practised over the sagittal suture, Garengeot successfully elevated a portion of bone which pressed upon the longitudinal sinus, and made the patient quite comatose. The depressed piece of the cranium could not have been so advantageously raised, had the trepan been applied in any other situation. But a still stronger argument in favour of this practice, when the case at all requires it, is the fact, that wounds of the longitudinal sinus, and the hemorrhage resulting from them, are not attended with any serious danger. Sharp mentions his having twice seen a bleeding of this kind. Another in 490 TftErHINK. stance is also recorded in Warner's Cases' A child received a wound on its forehead : the two parietal bones were fractured, and a portion of each was depressed on the dura mater. The child lived a month, without any operation being done; but at the end of this time, Warner applied the trepan. He found a splinter of bone sticking in such a way into the longitudinal sinus, that it could not easily be got out; consequently, he enlar- ged with a lancet the opening in which the splinter was entangled. The hemorrhage, which was copious, was easily suppressed by the application of a little dry lint, and the child was relieved, though it died at the end of two months, after suffering a variety of symptoms, which had no connexion with the wound of the sinus, the opening of which soon healed. The fourth case, rela- ted by Marchettis, also proves, that wounds of the longitudinal sinus are not fatal. Pott and Callisen have since recorded other facts, tending to the same conclusion. (See Syst. Chir. Hodierna , Part 1, p. 659, Edit . 1798.) Whenever a depressed fracture can be ele- vated to its proper level, without applying the trephine, and with the mere aid of a pair of for- ceps, or an elevator, trephining should never be performed, unless there be strong reason to apprehend, that blood, or matter, lodged on the surface of the dura matter, contributes to the production of the bad symptoms, and ought to be discharged. The scalp having been divided, if neces- sary, and the pericranium scraped from the surface of the bone, according to the com- mon precepts and practice, the next thing is the application of the crown of the trephine. The surgeon is first to make a little impres- sion with the point of the centre-pin, for the purpose of marking the place where it will work, when the crown of the trephine is applied in the proper situation ; for, where such impression is made, the operator must make a small hole with a perforator, in order to fix the point of the centre-pin, on which the crown of the instrument turns back- ward and forward, as on an axis, during the first stage of the operation. Mr. Savigny’s centre-pins make a perforation, without the need of any particular instrument for the purpose, and, in this respect, are advan- tageous. The point of the centre-pin having been fixed, the trephine is to be turned by regular semi-circular motions, alternately to the right and left, which object is effected by steady pronations and supinations of the operator’s hand. The teeth of the saw having made a tolerable circular groove, in which they can steadily work, the centre-pin becomes useless, and, as it would, if not withdrawn, or removed, certainly injure the dura mater and brain, by reason of its pro- jecting further than any other part of the instrument, it would be an unpardonable blunder to let it’ remain, after a proper cir- cular groove has been formed by the teeth of the saw. The beginning of the sawing may be executed boldly and quickly ; for, the operator runs no hazard of doing mischief. It is necessary occasionally, with a view of facilitating the action of the instrument, to clean away the particles of bony matter, vfith a little brush, usually kept for the pur- pose in every box of trephining instruments. Were this plan neglected, the action of the cylindrical saw would be very much clogged. The operator, however, must increase his caution, when the sawing has made greater progress ; for, were he to be too bold, he might sometimes lacerate the membranes of the brain with the teeth of the instrument, particularly, as the thickness of the cranium is subject to infinite variety, both in different parts of the same head, and in different sub- jects. Let the surgeon, therefore, never for- get to examine frequently with the point of a quill, whether any part of the circular groove is cut through or nearly so ; for, when this is the case, the instrument must only be worked in such a way, as to make pressure upon, and cut the part of the cir- cle which yet remains to be divided. In some few cases, it is said, that the surgeon can distinctly feel, when the teeth of the saw reach the diploe, or medullary struc- ture, between the two tables of the cranium, and some writers have rashly directed us to saw with boldness, till the sensation of this occurrence is communicated to our hand and iibgers.” However, I believe, this possibi- lity of discriminating the arrival of the teeth of the saw at the diploe is so uncommon, and so fallacious, that it should never be ex- pected, or relied cn. Nor ought the surgeon to saw with incautious force and rapidity, till he sees the teeth of the trephine bloody, which appearance has been set dowti as another criterion of their having reached the diploe. I have already stated, that a great many skulls have hardly any space be- tween several parts of the two tables. This is particularly often the case in old persons. A prudent man will always prefer exerting a little force for the purpose of breaking some of the bony connexion, retaining the circular piece of bone, to running any hazard of injuring the dura mater, by sawing too deeply. After a certain time, therefore, it is better to lay down the trephine, and endeavour to elevate the portion of bone, with the aid of a pair of forceps, construct- ed for the purpose, and kept in most cases of trephining instruments, or else by means of an elevator, which is still more calculated for the purpose. When the circular piece of bone has been taken out,' and the edges of the perforation are unequal, and splintered, the irregularities are to be cut off with the lenticular knife. When there is extravasated blood under- neath the opening which has been made, it sometimes spontaneously makes its escape, and, if it should not do so, the surgeon must remove it himself. If one perforation of the skull should not suffice for letting out the blood, as much more pf the cranium ought to be removed with the trephine. TftEFHINL. mi circumstances way require ; there being no comparison between the danger of repeating the application of the instrument, and that of leaving a quantity of undischarged, com- pressing fluid, on the surface of the brain. Certainly, many facts on record evince, that the dura mater may be very extensively un- covered, without dangerous consequences. Sarrau saw a whole parietal bone exfoliate, in consequence of a blow on the head. Blegny relates a similar case ; and Saviard makes mention of a woman, who had lost the upper part of the os frontis, both the parietal bones, and a large portion of the os occipitis, all of which had come away at the same ; yet she recovered. Vaugion, how- ever, who also seems to relate this identical case, describes the exfoliation as not being quite so extensive. I am of opinion, notwithstanding these facts, that exposing a large part of the dura mater with the trephine is, by no means, an operation exempt from serious danger. And, what I conceive confirms this statement, is my having known instances, in which per- sons, who had been rashly advised to submit to being trephined, for the cure of violent pains in the head, &,c. died, in consequence of the operation. I make this observation, well aware of the successful instance of the practice recorded by Schrnucker. ( Walir - 7iehin. B. 1 , p. 434.) However, [perfectly coincide with writers, who direct the removal of as much bone, as is necessary in order to be able to remove the whole of the pressure from the surface of the dura mater. The application of the trephine, in cases of large extravasations, must in particular be made several times, when the situation of the fluid does not favour its escape. However, in this circumstance, Sabatier iays, that we should not make numerous perforations all along the extent of the ex- travasation ; but, only a counter opening, as is done on the soft parts. This author ex- presses his surprise at there not being on re- cord many examples of counter-openings made in the cranium, since analogy demon- strates their utility. I cannot help remark- ing on this part of the subject, that one very obvious objection to make openings of this kind in the cranium, is the impossibility of knowing with certainty, whether blood lies under any particular part of the skull ; whereas, in abscesses of the soft parts, the surgeon feels the fluctuation of the matter, and knows that his counter-opening will be made in the cavity containing it. One might also have occasion to make more than one perforation, in order to discharge blood ex- travasated beneath the skull, when the blow has happened near a suture, to which the dura mater continues adherent ; for, a single opening made only on one side of the suture, might only give vent to a part of the extra- vasation. If we should not find blood lodged under the cranium ; but the dura mater should seem elevated, tense, dark-coloured, forming a prominent fluctuating tumour, outward, it Vor. U* A3 may be cautiously opened with a lancet, or bistoury, with a view of letting out any collection of blood underneath. In the arti cle Head , Injuries of, l have stated the result of Mr. Abernethy’s experience, in' regard to the operation of opening the dura mater. This gentleman found, that the method never effectually discharged all the blood, but only the serous part^of it. The evacuation of any of the compressing fluid must, how- ever, be desirable ; and, if the surgeon can not do more, yet he has fulfilled bis profes- sional duty. The utility of trephining is not limited to discharging extravasated blood, or matter, lodged underneath the skull. This operation frequently enables us to elevate depressed portions of bone. The latter objects can often be accomplished by merely making one perforation. Sometimes, several per- forations are requisite to be made near each other. Authors even state, that it may also become necessary to remove the interve- ning portions of bone with a pair of cutting forceps. The depressed part may then be easily raised by means of an elevator. Oc- casionally, indeed, I may say very often, the best practice is to remove the depressed portion entirely, when its total separation from the rest of the skull can be accom- plished by cutting across the base of the de- pressed piece. If any splinter stick in the dura mater, and should not admit of being- withdrawn, without enlarging the wound in. the membraue, the surgeon ought not to be afraid of doing this with a sharp instrument According to some quick-inferring writers, if, after dividing the dura mater, the surface of the brain appears smooth and flabby, with a fluctuation, we may conclude there is an abscess in its substance ; and these authors, more enterprising with their pens, it is to be hoped, than with their scalpels, sanction the method of carrying the point of the bistoury to the depth of an inch, if circumstances ren- der so deep a puncture necessary. “ But,” says Richerand, “ prudence forbids us to go further. Cutting the surface of the brain causes no pain, and it produces less danger, than one might apprehend ; but, experience and observation have proved, that the essen- tial parts of this organ are situated near its base, and that its surface may be removed without danger, or pain .” ( JVosogr . Chir. T 2, p. 301, Edit. 3.) After the operation of trephining, the di- vided scalp is to be placed as nearly as possi- ble in its natural situation, and lightly dress- ed with a simple pledget of any common unirritating ointment. In applying the dress- ings, the surgeon should invariably keep in view these objects ; namely, to let whatever •is put on the wound be as light as possible, not apt to make pressure on the brain, and of a nature, which cannot excite irritation. All stimulants are to be strictly avoided ; nor will any bandage be better than an ordinary night-cap of sufficient size to be put on with facility. It may be secured with bits of tape, which are to be tied under the jaw. The practitioner should not now conceive, TRICHIASIS. iite that he has done ail that he ought to do. Let him remember the urgent necessity of keeping off", or diminishing, the inflamma- tion of the dura mater and brain, which is still to be feared. Let him bleed the pa- tient largely and repeatedly ; exhibit saline purges, glysters, and antimonials ; and if the symptoms continue, let him apply a blister to some part of the head I shall avoid, however, any repetitions on this subject, by referring to Head, Injuries of. The aperture in the skull usually becomes closed with soft granulations, which slowly acquire a hard consistence. These almost constantly grow from the edge of the per- foration, and seldom from the surface of the dura mater. While the cicatrix is soft, it should be protected from external injury with a thin piece of horn, or metal. Exfo- liations from the margin of the perforation sometimes retard the healing of the wound ; but, now that the practice of dressing with drying spirituous applications has been ex- ploded, and the removal of any part of the scalp is condemned by all the best surgeons, these unpleasant consequences are rendered much less frequent, than in former days. The reader may find an account of the operation of trepanning, or trephining, in every system of surgery ; but, he should particularly consult the writings of Sharp, Le Bran, Dionis, Bertrandi, Pott, Sabatier, Schmucker, Abernethy, Desault, Callisen, liicherand, &c. Several parts of the Me- moires de l’Acad. de Chirurgie are also high- ly deserving of perusal TRICHIASIS, (derived from the hair) denotes a faulty inclination of the eye- lashes inwards against the globe of the eye. According to Scarpa, the disease presents itself under two distinct forms : the first is, where the cilia are turned inwards, without the natural position and direction of the tarsus being at all changed ; the second con- sists in a morbid inclination of the tarsus in- wards, ( Entropium ) and consequently of the eyelash towards the eyeball. ( Trichiasis .) The first form of this disease is said both by Beer and Scarpa to be uncommon, nor has it come under the observation of the latter writer more than once- and, in this in- stance, only some of the hairs had changed their direction. On this point, however, Mr. Travers is completely at variance with the foregoing authors, as he describes an inver- sion of the cilia as frequently existing inde- pendent of entropeon. {Synopsis, p. 232.) The second species, or form of trichiasis, or that which consists in a folding inwards of the tarsus and cilia at the same time, is the case which is commonly met with in prac- tice. It may be either complete, affecting the whole of the tarsus ; or incomplete, oc- eupying only a certain portion of the edge of the eyelid, most frequently near the ex- ternal angle of the eye. Sometimes, the disease is confined to one eyelid ; at other times, it affects both ;. and occasionally the patient is afflicted with it in both eyes. Some writers, among whom is Beer, ( hrjnr r.on fan Avgenkr. R. 2, v- U8,) ad- mit a case, which they call disliehiasis, aim which they suppose to be produced by a double and unusual row of hairs. But ac- cording to Scarpa, this third species is only imaginary, and the reason of such subdivi- sion seems to have arisen from not recol- lecting, what was long ago remarked by Winslow and Albinus, that although the roots of the cilia appear to be disposed in one line only, they form two, three, and in the upper eyelid even four rows of hairs, unequally situated, ‘and as it were confused. Whenever, therefore, in consequence of dis- ease, a certain number of hairs are separated from each other in a contrary direction and disorderly manner, the eyelash will appear to be composed of a new and unusual row of them, while, in fact, there is no change^ either with respect to their number, or na- tural implantation. It is not an easy matter to determine pre cisely, says Scarpa, what are the causes, which sometimes make a few of the hairs deviate from their natural direction, while the tarsus continues in its right position They are commonly referred to cicatrices in consequence of previous ulceration, whereby the cilia fall off, and those which are growing are hindered from taking their proper direction. There must, however, be other causes sometimes concerned ; for, in the case seen by Professor Scarpa, two or three hairs were turned inwards against the eyeball, although there had been no preced- ing ulceration, nor cicatrices, of any part of the tarsus. Indeed, Scarpa is inclined to believe, that the small ulcers and scars, which are sometimes formed upon the in- ternal margin of the tarsus, are more likely to cause the second form of the disease, or the inversion of the edge of the eyelid, and, consequently, of the cilia towards the globe of the eye. As these ulcers, when neglect- ed, destroy the internal membrane of the eyelids near the tarsus, it necessarily follows that, in proportion as they heal and dimi- nish, they draw along with them and turn inwards the tarsus, and hairs inserted into it. And since they do not always occupy the whole extent of the internal margin of the eyelid, but are sometimes confined to a few lines, in the middle, or extremity, near the external angle of the eyelid, so alter the cicatrices are formed, the whole of the hairs are not invariably turned inwards, but only a certain number of them, which correspond to the extent of the ulccr9 previously situa- ted along the internal edge of the tarsus. Indeed, in every case of imperfect trichiasis from a cicatrix of the inner margin of tk6 eyelid, the tarsus and cilia are every where in their natural situation, except opposite the part, where the ulcers formerly existed Also, if the eyelid be everted, its internal membrane, near that part of the margin cor- responding to the seat of the trichiasis, will be found pale, rigid, and hardened, the inver- sion of the cartilaginous border and of the cilia being plainly the effect of the contrac- tions of the cicatrized point. Chronic, ophthalmies of lon£Continuanre TRICHIASIS, *m sometimes bring on the complaint, in conse- quence of the skin of the eyelids being kept for a long time in a state of distention and oedema, terminating in a considerable relax- ation of it. And, according to Beer, the too long continued use of emollient poultices may have the same effect. ( Lehre , 4'C. B. 2, p. 113.) The cartilaginous margin of the eyelid then loses the proper support of the integuments, inclines towards the eyeball, and afterward turns inwards, drawing the eyelashes along with it in the same impro- per direction. Long-continued puriform discharges from the ciliary glands likewise spoil the shape and consistence of the car- tilage of the eyelid, and therefore not unfre- quently occasion trichiasis. Scarpa doubts, whether a spasmodic contraction of the orbicularis palpebrarum muscle can ever be a cause of the disease. The annoyance, which must necessarily result from the hairs perpetually pressing upon the cornea and white of the eye, as Scarpa observes, may be easily imagined. The evil is rendered still greater by the hairs, which are turned inwards, becoming much longer and thicker, than those wffiich retain their natural direction. And although the trichiasis be confined to one eye, both the eyes usually suffer from the effects of the disease. Indeed, generally, the eye on the sound side cannot be moved without occa- sioning pain in that which is exposed to the irritation and friction of the inflected hairs. In almost all instances, both the eyes are very irritable, and incapable of bearing the light. As, in cases of incomplete trichiasis, she patient retains some little power of open- ing the eyelids for the purpose of seeing, and that most frequently towards the internal angle of the eye, the head and neck are often inclined in an awkward manner, so that in children a distortion of the neck and shoulders is at last produced, which cannot he rectified without difficulty, even after the trichiasis is cured. Unfortunately, also, children are impatient of the uneasiness ari- sing from the inflected hairs, and, therefore, are continually rubbing the eyelids, whereby all the ill effects of the complaint are much increased. The cure of the second species of trichia- sis, or that which is commonly met with in practice, is accomplished by artificially everting the eyelid, and fixing it permanently in its natural position, together with the eyelashes, which irritate the globe of the eye. According to Professor Scarpa, this indication is perfectly fulfilled by the exci- sion of a piece of the skin close to the edge of the eyelid, of such a breadth and extent that, when the cicatrix is formed, the tarsus and margin of the eyelid may be turned out- wards, and sufficiently separated from the eyeball, the cicatrix of the integuments af- fording a point of support fully adequate to keeping the parts in their natural position and direction. Scarpa believes, that there are now very few modern surgeons, who, with a view to the radical cure of this dis- ease, place any confidence either in pluck- ing ont the inverted eyelashes, bending them outwards, .and retaining them so by means of adhesive plaster; or in plucking them out, and destroying their roots with caustic : much less in extirpating the edge of the eyelid along with the hairs, or dividing, the orbicularis muscle on the internal surface of the eyelid, under an idea that the disease is sometimes produced by a spasmodic con- traction of it. The following is the mode of proceeding recommended by Scarpa. The patient be- ing seated in a chair, if an adult, or, if a child, laid upon a table, with the head rais- ed, and firmly held by an assistant, who must stand behind the patient ; the surgeon is to ( )nsh outward, with the end of a probe, the lairs, which irritate the eye. Then, with a pair of dissecting forceps, or the ends of his fore-fingerand thumb (which answer equally well, and in many cases much better, than forceps,) the operator should lift up a fold of the skin ot ihe affected eyelid, taking great care that the piece which is taken hoid of corresponds exactly to the middle of the whole extent of the trichiasis ; for some- times the whole, sometimes a half, and, in other instances, only a third of the extent of the tarsus is inverted. The surgeon, with bis left band, must raise the fold of the skin, more or less, according as the relaxation of the integuments, and the inversion of the tarsus, are more or less considerable. The reason of this is evident, viz. the greater the quantity of skin is which is raised, the greater is the quantity which will be cut away. Sup- posing the patient to he an adult, as soon as the fold of skin has been raised in a certain degree, the surgeon must request him to open his eye, and if in this act the tarsus and eye- lashes resume their natural place and direc- tion, file portion of skin already raised will be sufficient for the purpose. When the in- teguments are elevated, by means of a pair of dissecting forceps, and care is taken to lay hold of the skin precisely at the middle point of the whole extent of the trichiasis, it necessarily follows, that the consequent sec tion^f the skin will form an oval, and that the greatest width of the wound will cor- respond exactly, or nearly so, to the middle of the eyelid, and its narrowest parts to the angles, or commissures of the same. This contributes very materially to make the ci catris correspond to the natural fold of the eyelid, and hinder the origin of a disease of an opposite nature to the one about to be re- medied, towards the angles of the eye, viz. a turning out of the commissures of the eye lids. See Ectropium. Besides this caution, relative to the situa- tion and figure of tue fold of the integuments to be cut off, the surgeon must be careful that the division of the skin be made very near the inverted tarsus. Were this circum- stance neglected, the operator might have the mortification of finding after the wound is healed, that although the eyelid is shorten* ed on the whole, from the eyebrow to the place of the recision, yet it is not equally so at the space which is between tbe edge of the eyelid and the cicatrix of the skin IJcnce the tarsus would not be turned ontward 5.00 TRICHIASIS. ficiently to keep the eyelashes from rubbing against the eye. The surgeon holding up the fold of skin by means of the forceps in his left hand, is with a pair of probe-pointed, sharp-curved scissors, to cut off (he whole of the duplica- ture, being first sure (hat one of the blades of the instrument is applied close to the edge of the eyelid. If the eyelids should be affected, the same operation musr immedi- ately be done upon bolh of them, with such cautions, and in such proportion, as the ex- tent of the disease, and the degree of inver- sion of each eyelid may require. Scarpa next dissuades us from employing any suture to unite the wound, and repre- sents that it will be sufficient to keep the eyebrow as much downward as possible, if Ihe operation has been done on the upper eyelid, or if on the lower, to support it against the inferior arch of the orbit, by pressing it from below upwards, so as to keep the edges of the wound from becoming separated. Then the lips of the wound arj^to be brought exactly together by means of adhesive plas- ter, which should extend from the superior arch of the orbit to the zygoma, and the maintenance of this state of the wound will be still more securely effected, by placing two compresses, one on the eyebrow, and another on the zygoma, together with a bandage. On the other hand, Laugenbeck disapproves of the omission of sutures, by which he finds that the wound may be both more accurately and expeditiously united. Indeed, he expresses himself generally in fa- vour of sutures, where the wounded part is liable to be disturbed by the continual ac- tion of the muscles. ( JYeue Bibl. B. 1, p. 4J5, fyc. 12mo. Hanover , 1818.) Langen- feeck, however, takes care to withdraw the ligatures in about twelve, or at most twenty- four hours, as their longer continuance would produce suppuration. Beer also par- ticularly insists upon the utility of bringing the edges of the incision together with a su- ture ; and both he and Langenbeck employ forceps, the ends of which have transverse pieces, calculated to take better hold of the slip of skin to be removed. (Le/tre, fye. B. ‘2,p. 114.) On taking off the first dressings, the third day after the operation, the surgeon will find, says Scarpa, that the patient can open his eye with ease, and that the inverted tarsus and eyelashes have resumed their natural position and direction. In the par- tial or incomplete trichiasis, or that which only occupies a half, or a third of the whole length of the tarsus, and in subjects who have had the skin of the eyelids very loose, Scarpa has often found the wound perfectly united on removing the first dressing. When, however, only a part of the inci- sion has healed, while the rest seems dispo- sed to heal by suppuration and granulation, the surgeon i3 to cover the wound with a small piece of lint, spread with the unguen- tum cerussai ; and if the sore should be- come flabby. it must be occasionally touched with the argentum nitratum, until the cure is finished. With regard to the first form of this dis- ease, or that in which the eyelashes pro- ject against the eyeball, without the natural position of the tarsus being at all altered, (a case which is fortunately rare) the ac- complishment of a cure is very difficult, since neither the pulling out of the hairs, nor burning the situation of their roots, are means at all to be depended upon for pro- ducing a complete cure of the disorder ; and turning the tarsus out of its natural po sition would make the patient liable to an irremediable dropping of the tears over the cheek attended with a chronic thickening of the lining of the eyelid. It has only- been in youngish individuals that Beer has ever seen the repeated and careful extrac- tion of the cilia effect a radical cure. (See Lehr e von den Augenkr. B. 2, p. 121.) In the instance of this form of the disease, which Scarpa met with, only two or three of the eyelashes inclined against the eyeball. He found, on turning the eyelid a little out, opposite to the situation of the faulty hairs, that he could not, indeed, completely put them in their natural position ; but he saw' that he could thus remove them so far from the cornea that they would not rub against it without altering the position of the eye- lids so much as to occasion a perpetual dis- charge of the tears over the cheek. And, as in the patient alluded to, the skin about the eyelid was very tense, Scarpa made an incision with the back of the lancet, near the tarsus, three lines long, and took away a small piece of skin of the same length, but very little more than one line broad. When the cut healed, the operation was found to answer as well as the nature of the case would allow, though the cure was not complete. The trichiasis being cured, something more always remains to be done for the purpose of correcting the cause of the dis- ease, as well as curing the disorder of the eye, occasioned by the previous friction and irritation of the inverted hairs. The usual indications are to restore the tone of the vessels of the conjunctiva, to lessen the swelled Meibomian glands, and obviate opa- city of the cornea. Some new methods of performing the operation for the cure of trichiasis, have been proposed by Dr. Crampton, Mr. Saun- ders, and Schre^er. The following is the account which Dr. Crampton gives of his plan, which lie tried in one instance with complete success “ Let the eyelid be well turned outwards by an assistant ; let the operator then, with a lancet, divide the broad margin of the tarsus completely through by two perpendi- cular incisions, one on each side of the in- verted hair or hairs ; let him then, by a transverse section of the conjunctiva of the eyelid, unite the extremities of the perpen- dicular incisions. The portion of cartilage contained within the incisions, can then, if inverted, with case he restored to its ori- TRICHIASIS. oinal situation, and retained there by small strips of adhesive plaster, or, perhaps what is better, by a suspensorium palpebrec, adapted to the length of the portion of the tarsus, which it is intended to sustain, should one or two hairs be displaced without in- version of the tarsus.” ( Essay on the En- tropeon, p. 55.) Mr. Travers informs us, that, in cases of a circumscribed inversion, “ produced by ci- catrix from burn or wound," he has found Dr. Crampto'n’s method an etfeciual remedy. It is,added ; that the complete division of the conjunctiva and tarsal cartilage, inclu- ding the inverted portion, and parallel to its border, with the aid of sticking plaster, sometimes proved sufficient. Mr. Travers also sees no objection to the entire removal of that portion of the tarsal edge which is incorrigibly . inverted from such a cause, especially when combined with a preterna- tural growth of cilia from the Meibomian border of the tarsus. ( Synopsis , p. 356.) In one inveterate case, which was not effectually relieved by the frequent extrac- tion of the cilia, cauterizing the edge of the tarsus, the excision of a slip of skin, and smearing the eyelid with concentrated sul- phuric acid, as proposed by Helling, ( Hufe - land's Journ. St. 4, p 115) Schreger, with a pair of curved scissors, cut out a triangular piece of the cartilage of the eyelid at the place where the cilia were most trouble- some. The great benefit derived from the operation then led the same practitioner to suggest the removal of the whole of the in- verted edge of the tarsus, towards the inner canthus, where some irritation was yet maintained. The plan, though followed by severe pain, appears to have succeeded. (C7«r. Versilche , B. 2, p. 253.) Mr. Saunders entertained a favourable opinion of Dr Crampton’s operation for the cure of the disease in its early stage; but, he contended, such a vicious bending of the tarsus inward was often the consequence of repeated ophthalmy, attended with ulce- ration of the conjunctiva and inside of the eyelid, so that every endeavour to rectify the wrong position of the tarsus, and restore its original direction, would be fruitless. Hence he believed that its excision was de- cidedly indicated ; an operation which is said to be followed by no pain nor uneasi- ness, and which is 6ure in its effect. No particular shortening of the eyelid ensues ; the deformity is materially lessened ; and, unless the cornea be already too opaque, perfect vision is re-established. Mr. Saun- ders directs a piece of thin horn or a plate of silver, having a curvature corresponding to that of the eyelid, to be introduced un- der this part, with its concavity towards the eyeball. On this instrument the eyelid is to be stretched. An incision is to be. made through the integuments aud orbicularis palpebrarum down to the tarsus, immedi- ately behind the roots of the cilia. The cut should extend from the punctum laebry male to the external angle. The exterior sur- face of the tarsus is then to be dissected 1 until the orbital margin is exposed, when the conjunctiva is to be cut through di rectly by the side of the tarsus, which must now be disengaged at each extremity. The punctum lachrymale must be left uninjured. The operation is described as being simple, and if any embarrassment arises, it is from the hemorrhage of the ciliary artery, the blood sometimes obscuring the punctum lachrymale, just when the operator is about to divide the tarsus by the side of it. No dressings are required, it being merely ne- cessary to keep the eye covered for a few days. The skin will continue to be eleva- ted, just as the perfect eyelid was ; and, though less completely, yet enough to leave the pupil clear when the eye is moderately directed upward. In all the cases in which Mr. Saunders operated, a fungus grew from the wound. He recommends the excres- cence to be destroyed with caustic or the. knife. Respecting this operation I shall merely observe, that it is more, severe than that advised by Professor Scarpa, and even than the method of Schreger, and must leave greater disfigurement. Unless, therefore., the latter methods prove ineffectual,! should consider the practice unjustifiable. Nor is Schreger’s method allowable, except in cases which resist the milder plan, sanction ed by Beer, Scarpa, and all the best practi- tioners in ophthalmic surgery. Inversion of the lower eyelid is much less common than that of (be upper one. The late Mr. Saunders never saw this disease arise from the same causes which induce it in the upper eyelid, though he acknowledges the possibility of such a case. However, he met with several instances of the affec- tion, in consequence of encysted tumours, which, as they increased, carried the orbital edge of the tarsus outwards, and, in the same proportion, inclined the ciliary edge towards the globe of the eye. An inversion of the inferior palpebra is sometimes produced by inflammation and swelling of that part of the conjunctiva which connects the eyelid with the eyeball. In cases of ophthalmy this membrane often forms between the latter parts a distinct fold, which is situated just on the inside of the orbital edge of the tarsus, and pushes it outward; while the contraction of the orbi- cularis muscle turns the ciliary edge in- wards, and inclines it between the swelling of the conjunctiva and the eye. In this particular case, Mr. Saunders assures us v , that replacing the eyelid in the early stage of the disease, and maintaining it so until the ophthalmy has been lessened by proper means, will be found effectual. But when the conjunctiva is much, thickened and in- durated, Mr: Saunders recommends cutting such diseased part of it away, and the ap- plication of compresses to keep the orbital margin of the tarsus inward. (See also Travers’s Synopsis, p. 234 and 355.) Albinus has recorded a species of trichi- asis which originated from the growth and inversion of one of the linjrs upon the ffa- \J jAOSSj* 5U2 runcula lachrymalis. The plan ot relief con- sisted in plucking out the irritating hair ; but it is not mentioned whether the hair grew again. J. Scultetus , Trichiasis Admiranda , sive Jlforbus Pilaris Mirabilis, 12 mo. Norib. 1658. Scarpa suite principali Malattie dtu.ll Occhi. II. Crampton, Essay on the Entropeon, Lond. 1805. Saunders's Obs. on several practical Points relative to the Diseases of the Eye, Edit. 3. Richter's Anfangsgriinde der fVun- darzneykunst , B 3. G. J. Beer, Lchre von den Augen/crankeiteri, B.2,p. 1 1 1—1 17, 8t>o. Wien. 1817. Schreger, Chirurgische Ver- stiche, B. 2. JYeue Methods die Trichiasis zu Operiren, p. 253, 8vo. JYilrnberg. 1818. B. Travers, Synopsis of the Diseases of the Eye, p. 232—354. fyc. 8 vo. Lond. 1820. TRISMUS, (from to gnash the teeth.) The locked jaw. See Tetanus. TROCHAR, or Trocar. (from the French, trois-quart, three-fourths, from its point being of a triangular form.) An in- strument used for discharging aqueous fluids, and now and then, matter from different cavities in the body, particularly those of the peritoneum, and tunica vaginalis, in oases of ascites and hydrocele. Trocars are also employed for tapping the bladder, dropsical ovaries, &c. A trocar consists of a perforator, or sti- lette, and of a cannula, which latter is so adapted to the first piece of the instrument, that when the puncture is made, they both enter the wound together, with perfect ease, after which the stilette being withdrawn, the cannula remains in the wonnd, and gives a ready passage for the fluid outward. Such are the uses of a trocar, and the principles on which it should be construct- ed, It would be unnecessary in this w ork to detail every little particularity in the in- strument. I shall merely observe, that the triangular-pointed trocars seem to retain the greatest share of approbation ; for, al- though those of a flat, lancet-pointed shape outer parts with more ease, their cannulas are not large enough for the ready escape of fluids which are at all thick, gelatinous, or blended with hydatids, and flaky substan- ces. The trocar for puncturing the bladder from the rectum, should be longer than a common trocar, and of a curved form ; but as Mr. Carpue has explained, it should not be passed too high up the rectum, lest the peritonaeum be wounded. Surgeons ought always to have, at least three trocars ; one of full size, another of middling width, and a third of small dimen- sions. In cases of hydrocele, the latter is often preferable. *TRUSS. ( trousse . French.) Rracherium. A bandage, or apparatus, for keeping a her ilia reduced. A truss, which fulfils its in- tention properly, should compress the neck of the hernial sac, and the ring, or external opening of th~ hernia, in such a manner, teat a protrusion of any of the contents of the abdomen will be prevented w ith com- plete, security. Hence, it. is the indispensa- ble quality of a good truss, first to make effectual and equal pressure on the parts in- dicated, without causing pain, or inconve nience to the patient , secondly, not easilv to slip oat of its right situation, in the vary- ing motions and positions of the body. Trusses are either of an elastic or non- elastic kind. The latter are composed of leather, fustian, dimity, or similar materials. These cannot be at all depended on, and should, therefore, be entirely banished from surgery. Since, (as Mr. Lawrence has re- marked) the size of the abdomen varies, according to the different states of the vis- cera, and to the motions of its parietes in respiration, a non-elastic bandage must vary constantly in its degree of tightness, and keep up either too great, or too little pres- sure. The omentum, or intestine, easily slips out when the opening is not exactly closed, and the patient who wears such a bandage must be in a state of constant inse- curity. Those who lead an active life, or are obliged to use laborious exertions, will be more particularly exposed to risk. If the patient, after experiencing these defects, endeavours to remedy them by drawing the bandage tighter, he may confine the viscera , but he produces other inconveniences. The increased pressure injures the spermatic chord, and may affect the testicle : the inte- guments become red, painful, and excori - ated ; and the bandage must be entirely laid aside, until the parts have recovered. Rich - ter has often seen painful tumefaction of the testicle, hydrocele, and even cirsocele, produced from this cause, and entirely dis- sipated by the employment of a proper truss. ( Trait6 des Hernies, p. 24.) He also saw the pad of a non-elastic bandage excite, in the region of the abdominal ring, a consider able inflammation, which terminated after a few days in suppuration. The hernia ne- ver appeared again after the cure of the abscess. The inflammation nad extended to the neck of the sac, and obliterated that part. — ( Lawrence on Ruptures , Edit. 3, p. 69, 70.) The spring is a very essential part of every elastic truss, and it consists of a flat long piece of steel, which is adapted to the side of the body,f>n which the hernia is situated It is not a great many years since the spring used to be made of com- mon iron, and Arnaud and Richter express their preference to a mixture of malleable iron and steel, so that the instrument may be moulded by the hand to any particular shape ; but, as Mr. Lawrence well observes, a truss, which admits of such management, must be more or less liable to the objections which apply to inelastic bandages, and the only material, which possesses the requisite qualities of firmness and elasticity, •» well- tempered steel. The front part of the steel spring has an expanded form, anil, w hen the truss is properly applied, ought to be situated over the mouth of the hernial soc. The spring of a truss has commonly been a semicircle, with/the posterior end resting on the spine. Camper proposed to carry it round to the anterior superior spine of TltUSo. the ilium oa the sound side ; a plan, of which Scarpa highly approves. Trusses of this form lit with a degree of steadiness, which cannot be given to others, by tighten- ing the strap. They keep up the rupture better than even a stronger spring of the common kind. Under the back surface of the anterior end of the spring is placed the pad, which should be adapted in shape and size to the passage, which is intended to be shut up. The steel spring is usually covered with leather, is lined with soft materials, and after being put on the patient, is fas- tened in its situation by means of a strap, which extends from the two ends of the spring, round that side of the body, on which the hernia is not situated. Hare- skin; with the fur outwards, is sometimes considered the best covering for preserving the spring from the ill effects of perspi- ration. When it is necessary to make strong compression, as in large old ruptures, and in persons who cannot avoid labour and exercise, the elastic spring should be made accordingly thicker and broader. But, an object of the first-rate importance is to make the spring press equally upon every point of the body which it touches. This is what demands the earnest atteation both of the surgeon and the instrument-maker, especially as the hips of some individuals are fiat and narrow, while those of other persons are broad and prominent. A thick, flexible, metallic wire, accurately applied round the pelvis, will serve to take the mea sure and proper shape of the spring, which may afterward be altered a little if found necessary. The wire, however, should be somewhat longer, on account of the length of the spring.' The springs of trusses intended for chil- dren, and persons who do not undergo much labour and exertion, need not be made so strong as those designed for hard- working, active people. The idea, that children cannot wear steel trusses, is as erroneous as it is dangerous in its practical consequences ; a point, on which tVjr. Pott has strongly insisted. Trusses are sometimes fabricated with a pad moveable on the spring, instead of being riveted to it. This may be inclined upwards, or downwards, according to the form of the abdomen ; and it is retained at the desired point by a spring fitting into the teeth of a rack, in others, the plate con- tains a screw, by which the cushion is pushed further inward, or allowed to recede at pleasure. Although there cannot be a doubt, that some of these inventions possess considerable merit, and are in certain in- stances superiorly useful, it must be con- fessed, that, in general, their utility is not samuch greater, than that of common pads, as to. make amends for the want of simpli- city and the increase of expense. I should be sorry, however, to say any thing that would unfairly discourage all such inge- nious endeavours to improve an instrument. 603 so difficult 10 bring lo perfection a3 a truss; especially as I believe there are particular cases, in which pads, with racks, screws,, springs, kc. gaay be employed with great advantage. jNot withstanding every care, sometimes even elastic trusses cannot be hindered from slipping away from the part, which they are designed to compress. Sometimes they slip downwards, which in fat subjects is generally caused by the projection of the abdomen. Occasionally, ‘the fault consists in the instrument becoming displaced in the direction upwards, which mostly hap- pens in thin persons, and is produced by the flatness of the abdomen. In the first case* the displacement is to be prevented by the use of an elastic scapulary ; in the second, the slipping of the pad- upwards is to be prevented by the employment of a thigh strap. When a patient is afflicted with a rupture on each side, the two protrusions may be very well kept up by means of a single truss, made with two pads, which are joined together, at the exact distance of the rings from each other, by a piece of steel, ap- plied over the convexity of the symphysis of the pubes, and proportioned in length to the space between the two openings, through which the viscera descend. In such cases,, however, it is absolutely necessary to have the spring stronger, than if there were only one rupture. The truss should also be put ou that side of the body, upon which the hernia most difficult to retain is situated. There are some practitioners, however, who give the preference to the use of two single trusses, joined together in front and behind with suitable straps. With respect to the application and use of trusses, the following instructions seem to merit attention. 1. A truss should never be first applied, or changed, except when the patient is in the horizontal posture, and it is known P with certainty, that all the contents of the rupture are completely reduced. 2. The first applications of a truss should always be made under the superintendency of the surgeon himself j and care should be taken to put on the instrument in such a manner, that the lower third of the pad will compress the neck of the hernial sac against the os pubis, while the upper portion will compress the abdominal ring. The surgeon should also make the patient acquainted with the right manner of applying the truss ; the principles on which it keeps up the bowels, and affords a chans e of a rad cal cure ; the requisite cautions to be observed, he. When a patient first begins to wear a truss, he should be particularly careful not to he guilty of any imprudent exertions, and it behoves him to observe most attentively, that the instrument does not slip from its proper situation It will also be necessary for him to pay attention to the instrument being neither too ti^ht, nor too loose. TRET &04 3. The patient ought to be' provider with at least two trusses, which should be chan- ged every morning in bed. In order to save the truss, especially in fat persons who per- spire a gr^at deal, it is a good plan to lay a soft piece of calico under the pad. 4. An uneasiness about the ring, which always gives rise to a suspicion that a por- tion of intestine, or omentum, is protruded, makes it proper to take off the truss, care- fully examine the parts, and reduce them if they have descended. 5. When the skin is excoriated by the truss, the part may be cured by sprinkling upon it the povvder of acetite of lead, Ful- ler’s earth, lapis calamiriaris, &.c or bathing the part with an astringent lotion, it will also be right to protect the excoriated place with a piece of linen put under the truss. <5. When the pressure of the truss excites affections and swellings ot the spermatic chord and testicle, either the thigh strap must be relaxed, or the lower part of the pad made less prominent. And when strong pressure is absolutely necessary to keep the hernia reduced, the pad should have an ex- cavation in it over the spermatic chord. Whoevef wears a truss should be careful to employ it day and night, without interrup- tion, so that there may be no opportunity for the hernia to protrude again. If under the employment of a truss, the rupture once descends again, either a strangulation hap- pens from the narrowness of the neck of the sac ; or, at all events, the hope of a radical cure, which may have been entertained for years and months, is destroyed in a mo- ment ; for, experience has put it beyond all doubt, that, by the continual unremitted use of a truss, and the steady retention of the contents of the hernia, the neck of the her- nial sac, and the nog, may be gradually lessened in diameter, until they are entirely closed, and n radical cure of the rupture effected. This is more frequently observed in young subjects, seldom in aduits, and scarcely ever in persons of advanced years. But trusses must be worn along while ; nor should the patient venture to lay aside their use till after many cautious attempts ; be- ginning the experiment at first only in^the night-time, and not making it in the day till after a considerable period from the time, when he first thinks himself safe. The longer and more attentively a truss is worn, the greater is the hope of a radical cure. ( Callisen , Syst. Ckir. Hod. T. 2.) In the 2d vol. of the last edition of the First Lines of the Practice of Surgery, the truss for navel ruptures, which was devised by Mr. England and latterly preferred by Mr. Hey, is described ; and in the article Hernia , an account is given of the truss for umbilical hernia, invented by Mr. Murrison of Leeds, and described by Mr. Hey. In the same part of this Dictionary may also be found some observations, relative to the place, against which the pressure of the pads of trusses should be directed in cases of inguinal hernia, iri conformity to Sir A. Cooper’s description of the situation, at t m. which the parts first protrude from the ab- domen. TUMOUR. A swelling. In the present, article, I intend only to treat of what are usually called sarcomatous and encysted tumours. Mr. Abernethy thinks, that the manner in which tumours are formed is best illustrated by those which hang pendulous from the membranous lining of different ca- vities. This gentleman adverts to an ex- ample noticed by Mr. Hunter, in which, ca the cavity of the abdomen being opened, there appeared lying upon the peritoneum, a small portion of red blood recently co- agulated. This, on examination, was found to be connected with the surface, upon which it bad been deposited, by means of an attachment, half an inch long, and this neck had been formed before the coagulum had lost its red colour. (See Trans. for the Improvement of Med. and Ckir. Knowledge, Vol. 1, p. 231.) Mr Abernethy observes, that if vessels had shot through the slender neck, and organized the clot of blood, this would then have become a living part : it might have grown to an indefinite magni- tude, and its nature and progress would probably have depended on the organiza- tion, which it had assumed. He mentions his possession-of a pen, found growing from the surface of the peritoneum, and which was undoubtedly formed in the same man- ner as the tumour noticed by Mr. Hunter, viz. by vessels shooting into a piece cf ex- travasated blood, or lymph, and rendering it a living organized substance. Tumours, in every situation, and of every description, are probably formed in the same way. The coagulating lymph being effused, either ac- cidentally, or in consequeiTee of disease, is afterward converted into a living part, by the growth of the adjacent vessels and nerves into' it. Mr. Abernethy remarks, that, when the deposited substance has its attachment by a single thread, all its vascu- lar supply must proceed through that part : but, in other cases, the vessels shoot into it irregularly at various parts of its surface Thus, an unorganized concrete becomes a living tumour, which has at first no percep- tible peculiarity as to its nature. Although its supply of blood is furnished by the ves- sels oi the surrounding parts it seems to live and grow by its own independent powers, while its future structure seems to depend on the operation of its own vessels. Mr. Abernethy conceives, that the altered struc- ture of an enlarged gland affords no contra- diction to the above account, as, in this latter case, the substance of the gland is the matrix, in which the matter, forming the tumour, or enlargement, is deposited. The structure of a tumour, he observes, is some- times like that of the parts, near which it grows. Such as arc pendulous in joints, a re cartilaginous, or osseous. Fatty tumours frequently' form in the midst of the adipose, substance ; and he has seen some tumours growing from the palate, which had a slen- der attachment, and resembled the palate in structure. TUMOUR. However, this resemblance of the struc- ture of a tumour to that of the neighbouring parts, is not always observable. I have in my own possession a completely cartilagi- ft nous tumour, which I found in the midst of the fat near the kidneys. The pendulous portion of fat, growing from the perito- neum, and mentioned by Mr. Abernethv, serves as another instance of the fact ; and, one might add, that every polypus which we meet with, bears no resemblance in struc- ture to the neighbouring parts. Mr Aberne- thy mentions his having seen bony tumours, which were unconnected with bone, or the periosteum, and he observes, that the struc- ture of a tumour is, in general, unlike that of the part in which it is produced. When the eoagulable part of the blood is effused, and the absorbents do not take it away, the surrounding blood-vessels are sup- posed to grow into it, and convert it into a vascular tumour. The effusion of the coa- gulable part of the blood may be the effect of accident, or of a common inflammatory process, or it may be the consequence of some diseased action of the surround- ing vessels, which (diseased action) may in- fluence the organization, and growth ot the tumour. In the former cases, the parts surrounding the tumour maybe considered simply as the sources, from which it derives its nutriment, while it grows apparently by its own in- herent powers, and its organization depends upon actions begun and existing in itself. If such a tumour be removed, the surrounding parts being sound, soon heal, and a complete cure ensues. But if a tumour be removed, whose existence depends on the disease of the surrounding parts, which are still left, and this disease be not altered by the sti- mulus of the operation, no benefit is ob- tained. These parts again produce a dis- eased substance, which has generally the ap- pearance of fungus, and, in consequence of being irritated by the injury of the operation, the disease is in general increased by the means which were designed for its eure. it appears, therefore, that in some cases of tu- mours, the newly-formed partalone requires removal, whilst in others, the surrounding substance must be taken away, or a radical cure cannot be effected. {Abernethy’s Surg. Obs. 1804.) This gentleman conceives, that the irritation of the tumour itself, when once the swelling has been produced, keeps up an increased action in the surrounding vessels, so as to become a sufficient cause of the disease continuing to grow larger. As the tumour becomes of greater magnitude, it condenses the surrounding cellular sub- stance, and thus makes for itself a sort of capsule. The close, or loose manner, in which tumours become connected with the surrounding parts, seems to depend very much on the degree of irritation and inflam- mation excited in the circumjacent parts. When a tumour has been at all tender, pain- ful, and inflamed, it is generally found inti- mately adherent to all the neighbouring parts. Mr. Abernethv also believes, that the increa' Voi. II 64 sed irritation whicli a tumour creates when it has exceeded a certain size, may explain why some tumours, which are at first slow in their progress, alterward begin to grow with great rapidity. Ihe process by which tumours are form- ed, is commonly thought to be attended with an increased action of the vessels, which supply the swellings with blood. It is supposed, in short, to be (he same kind of process, which forms all the thickenings and indurations, which, under various circum- stances, occur in different parts of the human body. It has sometimes been named chronic inflammation, to distinguish it from that which is more quick in the production of certain effects, aud is often attended with a manifest throbbing in the part affected. This subject of chronic, or passive inflamma- tion is one, about which very little certain is known ; and the very name has commonly been admitted only on the supposition, that some kind of increased action exists in the vessels, though of a slower and less evident kind, than what prevails in acute inflamma- tion. According to Dr. Wilson Philip, the difference between what is called active and passive inflammation seems to depend upon “ the degree, in which the arteries supplying the i«a a tergo to the debilitated vessels are excited.” ( Laws oj the Vital Functions, p. ^82, Edit. 2.) If this position be satisfac- torily established, one important step will be made to a knowledge of the differences be- tween acute and chronic inflammation ; but, much would yet remain for explanation be- fore our ideas of the latter process would be at all complete In a work of considerable merit, Dr. Baroa of Gloucester, offers many considerations against the correctness of the ordinary doc- trines, respecting the formation of tubercles and tumours. By tubercles, he means disor- ganizations composed of one cyst, “ what- ever be its magnitude, or the nature of its contents,” and by tumours, he would under- stand “ morbid structures, that appear to be composed of more than one tubercle.” {On 1 uberculated Accretions of Serous Membranes t fyc. p. 213.) From certain appearances, traced in dissections, Dr. Baron infers, (hat all tubercles, wherever situated, and of what- ever 9ubs(ance composed, were at their commencement small vesicular bodies, with fluid contents ; hydatids, as he endeavours to prove. “ It is impossible to say, how minute they may have been at their origin, nor how- large they may grow, before their transfor- mations begin ; nor are we acquainted with the circumstances which occasion such transformations.” To these changes in hyda- tids, (accordingtothis writer,) certain tuber- cles owe their existence, and on the size, relative position, and structure of the tubercles, which are so formed, depend the characters of many of the most formidable disorganisations, to which the human body is exposed. (P. 215.) A single hydatid, when it is trans- formed (says Dr. Baron) will give rise to one tubercle. “ It may be pendulous, or embedded in any soft part, or it mav be- TL'MOl/H found between the layers of membranes, ami wherever the textures are of such a na- ture as to admit of its growth. It may be so small as to be scaicely visible, or, it may acquire a very great magnitude. Single tu- bercles are often seen in a viscus, while all the rest of the organ is free from disease, and its functions are performed in 'an uninter* vupted manner. But, it is evident, that the same state of the system, (whatever that may be,) which calls one tubercle into ex- istence, may generate an indefinite number. They may be diffused through the whole of a viscus, leaving nothing of its original tex- ture, or they may occupy any proportion of it, or extend to the contiguous parts, and in- volve them in the same form of disease.” (P. 216.) When hydatids growing in clusters, and hanging within cavities, become changed into tubercles, Dr. Baron conceives, that the morbid appearances must of course corres- pond in some degree, with the original dis- tribution of the parts. He has seen tubercles attached in this form to the choroid plexus, to the valves of the heart, to the. fimbriated extremities of the Fallopian tubes, aud to the omentum, and convolutions of the bow- els. In the latter instance, they were very minute, the largest not being bigger than the head of a pin, and their number defied all calculation. “ Other varieties in the arrangement of the elementary parts of morbid growths, will of course cause corresponding varieties in their appearance. Thus, when hydatids art enclosed, the one within the other , and are transmitted into solid substances , a section of these substances will exhibit a series of concen- tric laminae .” Another variety pointed out by Dr. Baron, is “ when an immense number of very small tubercles are generated in juxtaposition, and unite together. Wherever such an event occurs, the original texture of the part is en- tirely lost, and a mass of varying degrees of density and firmness formed. In the earlier stages of its growth, a granulated appearance may be distinctly traced ; but, in process of time, this disappears, the consolidation be- comes more complete, and substances of a gristly, or cartilaginous, or scirrhous texture may be found. 1 have traced (says Dr. Baron,) the whole of these gradations in the liver, the lungs, the pleura, the omentum, the peritoneum, and in tumours in other parts.” (P. 219.) “ Sometimes, small hydatids grow from the outer or inner surface of large ones, or float within them. I have seen, (says Dr. Baron,) from a source of this kind, the uterus and its appendages converted into an enor- mous misshapen mass, tubercles of the size of the fist growing from it, while these again were surmounted by smaller ones in many gradations. Some had glairy contents, others were in a state of scirrhosity, and others were but little changed, having thin delicate cysts, and containing a transparent fluid. “ But, perhaps, (remarks Dr. Baron) the xuost important variety of all, is when tuber- cles, originally distinct irom each other, ap - proximate as they increase in size, ulti- mately unite, and form tumours, which have received different designations, according to the predominant character of their contents and internal structure. It was chiefly to elucidate this part of the subject, that I made the distinction between the words tumour and tubercle, Sic.” (P.219.) By thus adverting to the primitive arrangement, number, size, &.c. of hydatids, and their sub- sequent mutations, Dr. Baron tries to ac- count for the varieties of encysted and sar- comatous tumours, fungus hcematodes, tu~ berculated sarcoma, scirrhous swellings, &c. kc. The late Dr. Adams, as is well known, referred cancer to the living state, growth, and multiplication of the hydatid. (On the Cancerous Breast , p. 77.) In order to account for the various appearances of the disease, he has divided hydatids into a number of species, as iymphatica, cruenta, and carcino- matosa, and suspectsthat there may be others. These, he affirms, are lodged in different cavities, or enclosed in a fungus, which is occasioned by any individual, or numbers, stimulating the surrounding parts to gene- rate it, for the purpose of dividing the dead from the living. This fungus is a nidus, formed altogether for the protection of an- other generation ; by means of it, the living families are separated from the dead, and their preservation is secured. They die, he says, without otherwise affecting the body in which they existed, but by their local stimulus, and he declares, that his object is to prove the animalcular existence of carci- noma. Now, according to Dr. Baron, this main position is the fundamental error of Dr. Adams’s book; for, “ in no rational, nor legitimate point of view may cancer be said to have an animalcular existence ; be- cause admitting, for the sake of argument, that hydatids are animalcules, it has, I trust, been shown, (says Baron,) that it is to the loss of the hydatical character altogether, and the transformations of these bodies , that the mor- bid appearances in this, and many other dis- eases, ure to be referred .” (P. 276.) Although 1 consider the evidence and re- marks, which Dr. Baron has adduced, in sup- port of his opinions in many respects inter- esting, the facts brought forward do not ap- pear to me to justify the conclusion, that the formation of tubercles and tumours original- ly depends upon hydatids, and their transfor- mation. That hydatids are sometimes found within diseased structures, and that cells, cysts, granulated, and tuberculated appear- ances ure often noticed in tumours of differ- ent kinds, are facts universally received But the presence of hydatids in the unchanged state is only an occasional circumstance, whereas, if they were generally a cause of tumours by undergoing some unexplained transformation, it is impossible to suppose, that some of them, at least, would not be more commoulyfou d in a distinct, unaltered form within, or around all swellings, imagined to proceed from clusters of them. As the growth of tumours, formed on these prind 11 MOL R 507 pies, could not, 1 imagine, "be accounted for, without supposing a continual multiplication and transformation of hydatids, either witli- in, or around the swellings, one would ex- pect, that some visible hydatids, previously to tbeir transfiguration, would certainly be apparent on minutely examining the interior and the circumference of the diseased struc- ture. Yet, I am not aware, that, such fact has been proved to be generally the case, either by the aid of the scalpel, or the mi- croscope. The observation of cavities, cells, and tuberculated appearances in some kinds of tumours, is no proof that such modifica- tions of structure are transformed hydatids. Besides, if my limits would allow me to con- sider this topic further, many reasons might be urged against the hydatid doctrine, arising from the consideration of the changes evi- dent in the blood-vessels, supplying parts, in which a considerable tumour is situated. Thus, we often see the trunks of the arteries, running towards such parts, doubled in size, just as is noticed, with respect to the carotid in the natural growth of the stag’s horn, and indicating, at least, that the formation and increase of swellings are effected through the medium of the blood-vessels. The sud- den effect of tying the arteries, by which a tumour is supplied with blood, would also be difficult to explain, if the growth of the swelling really depended upon some unde- fined transformation of hydatids. It seems to be generally admitted, that the growth of all tumours may be retarded, and that sometimes they may even be diminished by means of topical bleeding w ith leeches, and keeping the parts in a continuaiiy cool state, by the incessant application of cold sedative washes. Afterward, when the in- creased action of the vessels seems checked, and the tumour ceases to enlarge, discu- tients are indicated, such as frictions with mercurial ointment, pressure, electricity, rubefacient plasters, solutions of salts, blis- ters, and issues. Very few sarcomatous or encysted tumours, how r ever, are ever com- pletely removed by these local means. The swelling, on the contrary, generally increas- es, notwithstanding them, and the irritation of the disease by stimulants is not altogether unattended with danger of the affection be- coming changed by them into very malig- nant and dangerous cases, sometimes to a! I appearances cancerous. The most odviseable plan is to recommend the removal of sar- comatous tumours with the knife, while they are small, and in an incipient state. For thus they are got rid of by an operation, which is certainly trivial, compared with what might afterward become requisite, if the disease were allow ed to proceed, and attain an enormous magnitude. Tumours, Sarcomatous. These have been so named, from their firm, fleshy feel. They are of many kinds, some of which are simple, while others are complicated w ith a malignant tendency. Mr. Abernethy has attempted to form a classification of sarco- matous tumours, for the different species of which be has proposed names, deduced from the structure, which they exhibit on dissec- tion. This gentleman has named the kind of swellings, which lie first considers, Com- mon Vascular, or Organized Sarcoma. Un- der this title, Mr. Abernethy includes all those tumours, which appear to be con posed of the gelatinous part of the blood, rendered more or less vascular by the growth of vessels through it. The vessels which pervade this substance are, in differ- ent instances, either larger or smaller ; and more or less numerous; being distributed in their usual arborescent manner, without any describable peculiarity of arrangement. Perhaps all the varieties of sarcomatous tu- mours are at first of this nature. The struc- ture under consideration, is met with not only in distinct tumours, but also in the testis, mamma, and absorbent glands. When a common vascular, or organized sarcoma has attained a certain magnitude, the veins of the skin seem remarkably large, and their winding under the integuments excites no- tice. This kind of sarcoma is not at all tender, so that it may be freely handled, and also electrified, without, giving pain. The tumour sometimes grows to such a size that the skin bursts, the substance of the swelling sloughs out, and the disease isgot rid of. However, this mode of cure is at- tended with such terrible local appearances, and so much fever, &ic. that the removal of the disease w ith the knife is to be preferred. The second kind of sarcomatous tumour, noticed in Mr. Abernethy ’s classification, is the Adipose Sarcoma. Every one, at all in the habit of seeing surgical diseases, must know, that fatty tumours are exceedingly common. Mr. Abernethy believes, that these swellings are formed in the same manner as others, viz. in the first instance they were coaguiablc lymph, rendered vas- cular by the grow th of vessels into it, and that their future structure depended on the particular power and action of the vessels. According to Sir Astley Cooper, “ they are not composed of fatty matter only ; but the adipose membrane is increased, and their structure is similar, only somewhat more compact, to that of the fatty membrane i:i other parts of the body.” (Med. Chir. Trans. Vol. 11, p. 440.), This fact is very muck against the doctrine, which ascribes the ori- gin of tumours to hydatids and their trans- formation. Adipose sarcomatous tumours always have a thin capsule, formed by the simple condensation of the surrounding cel- lular substance. It adheres very slightly to the swellings, and, chiefly by means of ves- sels, which pass through this memoranons covering in orderto enter the tumour. As Mr. Abernethy has accurately described, the vessels are so small, and the connexion so slight, that, in removing the tumour, no dissection is requisite, as the operator may easily put his fingers between the swelling and its capsule, so as to break the little vas- cular connexions, and entirely detach the disease. The substance of adipose tumours is never furnished with verv large blood-vessels, and I'UMOUB the fear of hemorrhage, w^ich frequently deters surgeons from operating, is quite un- founded. It is an undoubted Tact, that there is no species of tumour, that c air be removed with so much celerity, with such apparent dexterity, or with such complete security against future consequences, as those of an adipose nature. However, now and then, when the tumour has been at all in an in- flammatory state, the capsqle becomes thick- ened, and intimately adherent to the surface ot the swelling, so that the separation of the disease is more difficult, and requires the knite to be more freely employed. The tumour also sometimes becomes, after in- flammation, closely adherent to the conti- guous parts. Adipose tumours often ac- quire an enormous magnitude. Indeed, there can be no doubt of the fact stated by Sir Astley Cooper, that they acquire a greater magnitude than any other swelling ever reaches. Mr. Abernethy relates an example of one, removed by Mr. Cline, which weighed between 14 and 15lbs., and which I saw myself previously to the opera- tion. Sir Astley Cooper also mentions the successful extirpation of several adipose tu- mours of immense size : one weighing 141b. 105. removed by himself; another. weigh- ing I5lbs. removed by Mr. Cline and a third, weighing 221bs. removed from a lady’s thigh by Mr. Copeland. But the most re- markable case is one, in which Sir Astley Cooper lately removed a fatty swelling which weighed, independently of the blood in it, 371bs. lOozs., and was situated on the ab- domen of a man, aged 57. (See Med. Ckir. Trans. Vol. 11 ,p. 440.) Although it is true, that when adipose swellings attain an enor- mous bulk, the immense size of a wound requisite for their removal, must he danger- ous, and is a strong argument in favour of having recourse to the operation at an ear- lier period, yet it is equally true, that large fatty swellings may be taken out, with a greater prospect of success, than any other kind of tumour of equal size. The next species of sarcoma, noticed in Mr. Abernethy’s classification, is what this gentleman names pancreatic, from the re- semblance of its structure to that of the pan- creas. This kind of disease, according to Mr. Abernethy, is occasionally formed in the cellular substance ; but, more frequent- ly, in the female breast, on that side of the nipple which is next to the arm. When a pancreatic sarcoma is indolent, and in- creases slowly, the surrounding parts, and the glands in the axilla, are not affected. But some of these swellings deviate from their common character, and become of a very irritable nature, occasioning severe and lancinating pain, and producing an in- flammatory state of the skin covering them, so that it becomes adherent to their surface. The absorbents leading to the axiila are also irritated, and the glands enlarged. Pancre- atic sarcoma does not grow to a very large size ; but, when its progress is unrestrained, the pain attendant on the disease becomes Janeinating, and so severe as to make the patients Feverish, and lose tbeir health and strength. Mr. Abernethy remarks, that, when the axillary glands become affected, one generally swells at first, and is extreme- ly tender and painful ; but afterward the pain abates, arid the part remains indurated. Another is then affected, and runs ihrougk the same course. To another species of sarcoma, Mr. Aber- nethy applir s the epithet mastoid, or mam- mary, from the resemblance which this gen- tleman conceives its structure bears to that of the mammary gland. This kind of dis- ease, Mr. Abernethy says he has not often seen. In the example which he met with, the tumour was about as large as an orange, and situated on a woman’s thigh. The swelling was removed by an operation ; but the wound afterward degenerated into a malignant ulcer, attended with considerable induration of the surrounding parts, and the woman died of the disease in two months. Mr. Abernethy conceives, that the whole of the s morbid part had been cut away, but that the contiguous parts had a disposition to disease, which was irritated by the ope- ration, and that if the nature of the case could have been known beforehand, it would have been right to have made a freer removal of the substance surrounding the tumour. Mr. Abernethy places the mastoid sarco- ma, between such sarcomatous swellings as are attended with no malignity, and the fol- lowing ones, which have this quality in a very destructive degree. The tuberculated sarcoma is composed of a great many small, firm, roundish tumours of different sizes and colours, connected to- gether by cellular substance. Some of the tubercles are as large as a pea ; others equal a borsebean in size ; most of them are of a brownish red colour; but some are yel- lowish. Mr. Abernethy mentions his hav- ing seen this species of sarcoma chiefly in the lymphatic glands of the neck. The dis- ease proceeds to ulceration ; becomes a painful and incurable sore, and ultimately occasions death. Another kind of sarcoma, mentioned in Mr. Abernethy’s classification of tumours, is distinguished by the epithet medullary , from its having the appearance of the me- dullary matter of the brain. It appears to be an exceedingly malignant disease ; com- municates to the lymphatic glands a similar distemper; ulcerates and sloughs, and at last proves fatal. It is particularly apt to make its attack on the testis, and it is treat- ed of in another part of this book. (See Testicle, Diseases of.) Mr. Abernethy includes also in his classi- fication, carcinomatous sarcoma. (See Can cer.) 1 must refer to another article, (Mamma. Removal of) for an account of the plan of removing sarcomatous tumours. Besides many operations, which have of late years been performed, and are remark- able, on account of the great size ot the swellings removed, others, still more inte- resting, claim attention, on account ot the nature and situation of the parts extirpated, TUMOUR. 509 On the excision of the thyroid gland, I need not here dwell, as it is elsewhere noticed. (See Thyroid. Gland ;) but I feel called up- on to mention some other very bold ope- rations, executed within the last few years- The first is that performed by Mr. Goodlad, oi Bury, in Lancashire. The case was an immense tumour, situated on the left side of the face and neck, and the base of which was about twenty-eight inches in circum- ference. The disease extended from the external canthus of the eye above to within three-quarters of an inch of the clavicle below, and some idea of the depth of its at- tachments may be conceived, when it is known, that the whole parotid gland was involved in it. For the purpose of obvia- ting all danger of hemorrhage, Mr. Goodlad began with tying the carotid artery. The nature of the operation will be best under- stood by adverting to the appearances after- ward presented by the wound. “ The whole sterno-mastoid muscle was exposed, and its fibres dissected clean, except about half an inch from its insertion into the cla- vicle. The wound extended backwards from behind the mastoid process to the tra- chea anteriorly, but became narrower in the direction of the muscle at the lower part of the neck. The submaxillary gland was exposed, and about one-fifth of its substance, not appearing healthy, was removed. The digastric and the greater portion of the myln-hyoideus were exposed The ramus of the jaw w as only covered by periosteum, except where covered by the masseter mus- cle, part of which, not appearing healthy, was dissected away The w r ho!e of the condyloid process of that bone was laid bare in the same manner, and behind it the pterygoid muscles were also exposed. The membrane of the cheek was only covered by a cellular substance, which did not ap- pear healthy; but sufficient skin was saved to cover the zygoma. The parotid gland was entirely removed This enormous wound healed in ten weeks ; but unfortu- nately the cure was not permanent ; the disease returned, and, fifteen months after the operation, the poor w^oman died. (See Med. Chir. Tram. Vol. 7, p. 112, fyc. Vol. 8, 1 5 § 2 -) Respecting the foregoing severe opera- tion, many surgeons may be inclined to doubt the propriety of tying the carotid ar- tery, as a preparatory step, and, indeed, it is positively condemned in an anonymous note attached to the above case, simple temporary pressure on the exposed vessel being represented as preferable. It appears tome, however, that Mr. Goodlad's method was justifiable, and on the whole the best, because the application of the ligature to the carotid not only removed the dangers of hemorrhage during the operation, but obvi- ated them afterward, and no doubt lessened the necessity for a prodigious number of ligatures, for vessels, wdiich w T ould other- wise have poured out a profuse quantity of blood. Nay f the hemorrhage is so profuse from the main branches of the external carotid, and mere pressure so uncertain of always commanding the flow' of blood, that the pa - tient may actually die from sudden loss of blood, as nearly happened in another very interesting case of removal of a large tu- mour involving also the parotid gland, and connected with the transverse process of the atlas, the basis of the skull, the meatus auditories, mastoid process, and angle of the jaw. The operator, Mr. Carmichael, in order to complete the dissection, was obli - ged to divide the trunk of the facial artery ; “ instantly (says he) an alarming gush of biood, which evidently came from a large vessel, followed the division ; and the dan- ger appeared the more imminent as the pres- sure, which Mr. Todd applied, with all the force he could exert vpon the carotid trunk , was actually incapable of repressing the ior- rent. There was not a moment to be lost. Mr. Collbs plunged a dry sponge to the bot- tom of the wound, and firmly pressed on the bleeding vessel, while 1 made a horizontal section of the tumour, till 1 arrived at the cavities occupied by the sponge, with the view of exposing as quickly as possible the mouth of the bleeding vessel. This was accomplished in sufficient time to save the patient’s life.’ Mr. Carmichael, at the conclusion of the history, remarks, that, if he were called upon to perform such an operation again, he would , in the frsl in- stance, pass a ligature under the carotid trunk, which might be tightened, or not, as occasion should require. The case here spoken of had a successful termination. One remark- able consequence was a paralysis of one side of the face, brought on by the division of the trunk of the portio dura in the opera- tion. (Bee Trans, of the King’s and Queen’s College of Physicians, Vol. 2, p. 101, 8vo. Dublin, 1818.) The next instance which I shall notice, of the removal of an enormously enlarged pa- rotid gland, is that lately recorded by Klein, the eminent operating surgeon at Stuttgardt. The patient w as a woman of seventy, and the swelling extended from the ear to the shoulder. In the operation, all the branches of the facial nerve were divided ; a piece of the masseter was left hanging ; the ex- ternal carotid artery and par vagum were left quite bare ; the dissected sterno-mastoid lay on on side ; and the temporal, external maxillary, and auricular arteries were of course divided, along with several arteries of the neck, yet the largest of these being tied, the bleeding was very inconsiderable. The event was so successful, that at 'the be- ginning of the third week, the wound was entirely healed. The same distinguished surgeon also re- moved a fatty tumour, extending from the buttock to the ham, and measuring thfoe feet one inch in length, and two feet six inches in circumference. Klein undertook its remo- val, on the supposition, that it was an en- cysted tumour lying above the fascia lata ; but it turned out to be a steatoma coming from beneath it, and reaching to the thigh- >10 TUMOUR. bone, and in every direction among the muscles, nerves, and blood-vessels of the thigh. At length, partly with the fingers, and partly with the knife, the fatty mas3 was separated from all its important con- nexions. Several vessels were tied, and among them the profunda femoris. How- ever, not more than a pound of blood was lost. The tumour, after its removal, weigh- ed 27lb. and three quarters. The patient, a woman 44 years of age, went on very well for eight days; but on the ninth, she was constantly complaining of uneasiness in the foot of the affected limb ; her pulse became weak and intermitting ; and she sunk in the most unexpected manner. (See Journ.fiir Chirurgie herausgegeben von D. L. Graefe und D. P. F. Walther, B. 1 , p. 106, fyc. Svo. Berlin, 1820; or Quarterly Journal of Fo- reign Medicine, $fc. Vol. 2, p. 373, <^c.) A question may be entertained, whether, in some morbid enlargements of the parotid gland, and parts extending deeply about the throat, it would not sometimes be better to be content with simply tying the carotid artery, and trying whether stopping this large supply of blood to the diseased parts, would not be followed by an absorption of the tumour ? Some facts, appertaining to this question, are noticed in the article Aneurism , where the aneurism by anasto- mosis falls under consideration. It will there be seen, that the result of this experi- ment is not sure of permanently repressing the growth of a tumour of this last kind, even when it has this effect at first. This uncertainty will, no doubt, incline many practitioners to prefer the bold method of extirpation. Yet others will perceive, that such an operation, notwithstanding its suc- cess in a few examples, is dreadfully severe, and must of itself in the generality of cases have fatal consequences. They will also be encouraged, in any similar instance, to try the effect of the ligature, by the cure which Sir A. Cooper accomplished, of an enormous cutaneous enlargement of the lower extremity by tying the artery in the groin. Indeed, I atn sure, that as the im- provements in modern surgery advance, the plan of curing tumours by cutting off their main supply of blood, will be much more extensively adopted, than has hitherto been the case. In this way, the surgeon may 4 attempt the dispersion of many tumours, which could not be meddled with in any other manner, and which, if left to them- selves, must have a fatal termination. Tumours Encysted. These, which are commonly named wens, consist of a cyst, which is filled .with different substances. When the contained matter is fatty, it is termed a steatoma ; when somewhat like honey, meliceris ; when like pap, atfuroma. These are the three species, into which writers usually divide encysted tumours. However, some of these swellings do not conform to either of the above distinctions, as their contents are subject to very great variety indeed, and are occasionally of an earthy, bony, or horny nature. Some en- cysted tumours of the latter description occasionally burst, and assume the appear- ance of horns, by the gradual projection of the matter secreted within their cysts. (See Sir Evcrard Home's Obs. on the Growth of Horny Excrescences , in Phil. Trans, for 1791.) . I remember seeing an excrescence of this kind removed some years ago from the scrotum of a man in St. Bartholomew’s Hospital. Sir James Earle performed the operation, and if I am not mistaken, the preparation of the disease is now in Mr. Abernethy’s museum. But still more re- markable specimens of such excrescences are preserved in the Anatomical Museum of St. Thomas’s Hospital ; one in particular, which resembles a ram’s horn in shape, and was removed from a gardener’s head at Kingston, by Dr. Roots. A further account of the case is given in Rees’s Cyclopajdia, article Horny Excrescence. I suppose every body in London has now seen in the British Museum the horn depo- sited there as a curiosity, and which, with another ol the same size, grew upon the head of a human subject What i3 equally curious, hairs are not unfrequently found growing in the cavities of encysted tumours, ( Delpech Precis des Mai. Chir. T. 3, p. 412 ;) and even teeth, more or less perfectly form- ed, have been strangely met with in the same situations. An interesting specimen of the latter occurrence, in a double encys- ted tumour in the orbit, was published some time ago by my friend Mr. Barnes, of Exe- ter. (See Med. Chir. Trans. Vol. 4, p. 316.) It is observed by Sir Astley Cooper, that it is when encysted tumours are situated upon the temple, and near the eyebrows, and other hairy parts, that they sometimes con- tain hairs : these 11 have no bulbs, nor ca- nal, and differ therefore from those, which are produced in surfaces of the body, which naturally form hair.” In sheep, the cysts sometimes contain wool. ( Surgical Essays , Part 2, p. 233.) The manner in which these horny excrescences are produced, is stated to be as follows : “ The horn begins to grow from tiie open surface of the cyst ; at first, it is soft, but soon acquires consider- able hardness ; at first it is pliant, but after a few weeks, it assumes the character of horn.” (Vol. cit. p. 235; see also Home in Phil. Trans, for 1791.) Encysted tumours are generally of a roundish shape, and are more elastic than fleshy swellings. However, the latter cir- cumstance depends very much upon the nature Of their contents, and the thickness of their cysts. As far as my observation extends, encysted tumours form more fre- quently on the head than any other part ; but they are very frequently met with in all situations under the integuments, and some- times in deeper places. Encysted tumours are also very often seen on the eyelids. According to Sir Astley Cooper, they mein general nearly globular, and when seated on the head, feci very firm, but upon tho fare they are attended with a fluctuation, TUMOUR 51 1 more or less obscure. The skin covering them, is generally uninflamed ; but it is now and then streaked with blood-vessels, which are larger than those of the surrounding in- teguments. “In the centre of the tumour on the skin, it often happens that in its early state, a black, or dark-coloured spot may be seen, which sometimes continues through the whole course of the disease. In general they are unattended with pain, are never in themselves dangerous, and only require re- moval from the parts in which they occur, and the unseemly appearance they produce. They move readily within the cellular membrane, if they are free from inflamma- tion, but the skin in general does not easily move over them.” (Surgical Essays, Pari 2, p. 230.) The greatest number of encyst- ed tumours, which this experienced surgeon has met with in the same individual, was sixteen, situated upon the head ; and he has seen nine in another patient, as many as which number on one person I have seen myself. Four, five, and six, as Sir Astley re- marks, are not uncommon. The largest, which he has ever seen, was equal in size to an ordinary cocoa nut, and grew upon the head ; but in general, they are not more than one or two inches in diameter. He considers them in some degree hereditary, as he has often heard a patient observe ; “ I have several swellings upon my head, and ray father (or my mother) had several.” They also frequently occur in several of the same family. (A 231.) According to Sir Astley Cooper, when en- cysted tumours are dissected, some part of their surface is found firmly adhering to the skin, while other parts are connected to it merely by the cellular membrane. The cyst itself is imbedded more or less deeply in the cellular membrane, and its thickness is different in different parts of the body. On the face, or near the outer canthus, the cyst is very thin; but on the back, it is much thicker, and on the head, it is so thick and firm, that it retains its form after the discharge of its contents, and is so elastic, that after being compressed, it readily ex- pands again to its former size. Within the cyst, Sir Astley Cooper remarks, there is a li- ning of cuticle, which adheres to its interior, and several desquamations of the same sub- stance are formed within the first lining. If the vessels of the cyst are injected, they are found to be numerous, but of small size. The cysts are occasionally met with in an ossified state. ( Surgical Essays, Part 2, p. 232,233.) It is the opinion of Sir Astley Cooper, that encysted tumours arise from the enlargement of the follicles, or glandu- lar pores, in consequence of the obstruction of their orifice. (P. 23d.) If this senti- ment were correct, the fact would furnish another consideration against the view taken of the formation of the tumours by Dr. Baron. However, it appears to me, that there are some reasons, which render the adoption of Sir Astley’s explanation diffi- cult; for, if encysted tumours were only enlarged follicles, they would not be found so far from the skin as they frequently are, as for instance within the orbit, and in other situations yet further from the surface of the body ; and the collections of sebaceous matter, which so often collects, as this gen- tleman observes, in the follicles of the skin of the nose, and may be pressed from them in the form of worms, would, if the cause assigned were true, make encysted swell- ings on the nose itself exceedingly com- mon ; yet this part is not so often the seat of such tumours, as other parts of the face. As far also as my observations extend, pres- sure cannot be said to have any share in giving rise to the formation of encysted tu- mours, because 1 have seen them chiefly in situations, where this kind of cause could not be suspected, as for instance, on the face and about the vertex, and not particu- larly round that part of the head, which is compressed by the hat. If also encys- ted swellings were owing to obstruction of the cutaneous pores with sebaceous matter, i apprehend few persons would escape the disease. The cure in the early stage would also be as easily effected by the timely re- moval of the alleged obstruction, as the cure of the little tender points on the nose, really caused by the lodgment of the seba- ceous matter in the cutaneous pores. This does not appear to me to be consonant to general experience. How the formation of steatomatous encysted swellings is to be thus accounted for, I cannot at all conceive. And, lastly, it is to be noticed, that the lit- tle swellings on the nose, arising in the way described, are, when they occur, frequently attended with soreness, from which true encysted tumours, at least in, the early stage, are completely free. These, and other reflections, lead me to believe, that the origin of encysted swellings cannot be satisfactorily explained upon the principles suggested by the above distinguished prac- titioner. However, as all his opinions on surgical questions are deservedly valuable, I subjoin the advice which he has given, founded upon the preceding doctrine. If the follicle can be seen only as a black spot . filled with hardened sebaceous matter, Sir Astley Cooper recommends introducing a probe into it, and squeezing the sebaceous matter out of the tumour, which is done with little inconvenience. But, if the con- tents cannot be pressed out without such violence as would create inflammation, he says, that the best plan is to make the open ing larger. Other surgeons have tried to cure encysted tumours by pricking them with needles, and squeezing out their con tents ; or by applying stimulating and dis- cutient applications to them. However, it is a practice which mostly fails, and, some- times, converts the case into a terrible dis- ease, in which a frightful fungus shoots out from the inside of the cyst, attended with immense pain and irritation, and often pro- ving fatal. (See Mernethy’s Surgical Ob- servations, 1804, p. 94.) Similar dangerous fungous diseases may also arise, whenever the surgeon, in cuttin? 51 2 TUMOUR. out encysted tumours, leaves any part of the cyst behind. The most adviseabie method, I believe, is to have recourse to the knife, before an en- cysted tumour has attained any considera- ble size. However, if it is large at the time of the operation being done, a portion of the skin must be taken away with the swell- ing, in the manner described in the article Mamma, Removal of. The chief piece of dexterity in the operation consists in detach- ing all the outside of the cyst from its sur- rounding connexions, without wounding it. Thus, the operator takes the part out in an entire state, and is sure, that none of the cyst remains behind. When the cyst is open- ed, some of the contents escape, it collapses, and the dissection is rendered more tedious and difficult. Such is the common opinion, which has always appeared to me correct. However, Sir Astley Cooper states, that the best man- ner of doing the operation is to make an in- cision into the swelling, and then to press the sides of the skin together, by which means the cyst may be easily everted and removed. If the attempt be made to ex- tract the tumour whole, “ the dissection is most tedious, and before it is completed, the cyst is either cut, or burst. So many incisions, and so much pain, maybe readily prevented by opening it freely by one inci- sion, raising its edge between the forceps,” and dissecting it from its adhesions to the surrounding membrane. ( Surgical Essays, Part 2, p. 240.) When the swelling is in the scalp, Sir Astley directs an incision to be made through its centre, from one side to the other, when its contents, which in this situation are very solid, are immedi- ately discharged in a mass of the same shape as the tumour. The cyst being raised with a tenaculum, may then be easily separated. With respect to encysted tumours of the eyelids, the atheroma and meliceris are said by Beer to form only upon the upper eyelid, on the side towards the temple, while he has always found the steatoma to be seated ei- ther in the vicinity of one of the eyelids, or sometimes over the lachrymal sac. The athe- roma and meliceris, he says, usually lie in the loose cellular substance directly under the skin of the eyelid, though sometimes more deeply under the orbicularis muscle, or even quite underneath the levator palpebrae supe- rioris, upon the convex surface of the tarsal cartilage, to which the swelling is then ge- nerally so firmly adherent, that it is impos- sible to remove this part of the cyst. En- cysted tumours of the upper eyelid are com- monly so moveable, that they can be push- ed above the superciliary ridge of the os frontis ; which is regarded by Beer as a very favourable circumslance in the operation. Though the atheroma and meliceris of the upper eyelid occasionally become as large as a pigeon’s egg, Beer has never known a stentoma in the vicinity of the eyelids ex- ceed the size of a hazel nut. Encysted tu- mours of the upper eyelid itself sometimes appear moveable, though they may be at the same time closely adherent to the car- tilage. Hence, Beer recommends moving the tumour about for a few days before the operation, and trying to push it above the superciliary ridge ; and if this cannot be done, the circumstance will prove that the swelling is connected with the cartilage, or, at least, is under the orbicular muscle, and the mode of operating regulated according- ly. With the yellow pappy substance, found in the cysts of arethoraatous tumours of the eyelids, fine short hairs, scarcely one line in length, are frequently blended. Some- times, as Beer remarks, the whole inside of the cyst is covered with these little short hairs, which may all be washed out, and are destitute of bulbs ; a fact also noticed by Sir Astley Cooper. It merits attention, however, that in tumours of the meliceris kind, formed upon the eyelid, Beer never met with hairs. ( Lekre von den Augenkr. B. 2, p. 607 — 609.) He remarks, that when encysted swellings of the eyelid are let alone, he has never known them produce any injury to the eye itself, excepting the hinderance to the opening of it, when they are large. On the other hand, if they be unskilfully removed, or rashly attacked with caustic, various ill consequences may ensue ; as for instance, fistulae of the lachry- mal gland, entropium from a shrinking of the tarsal cartilage, ectropium from destruc- tion of the skin, and the hare-eye from an actual shortening of the upper eyelid. In consequence of the inflammation caused by escharoties, Beer has more than once found the integuments so adherent to the tumour, that in the operation, the removal of a considerable piece of them was una- voidable. But, says he, when swellings of this nature are properly treated in good time, they may be removed without leaving any vestige behind, excepting a trivial scar. Professor Beer joins all the best modern surgeons in considering the entire removal of the sac, and the reunion of the wound by the first intention, as the safest and most ef- fectual method of curing encysted tumours of the eyelids. He admits, however, that the hinder portion of the cysts of some swellings of this nature upon the upper eye- lid cannot be dissected out, because it may be so closely adherent to the cartilage, that its excision would injure the latter part too much, and produce either an incurable eu- tropium, or an irremediable shortening of the eyelid. But steatomatous tumours, near the eyelids, may almost always be com- pletely dissected out, the only exceptions being cases in which the swellings happen to be situated between the lachrymal sac and the orbicular muscle, and so intimately connected with the first of these parts, that the back portion of the cyst could not be cut away, without permanently destroying the functions of the excreting parts of the lachrymal organs. However, when the swelling is not too strongly attached to the cartilage of the eyelid, Beer sanctions the removal of the whole of the cyst. He par ficularly insists upon the utility ol moving TUMOUR. the tumour a good deal about daily, for a few days before the operation, so as tt> loosen its connexions, and enable the sur- geon to push it over the edge of the orbit, where it may be steadily fixed during its re- moval. (Z>\ 2, p. 612.) Excepting a few instances, in which the skin was diseased, and firmly adherent to the cyst, Beer has never found it necessary, in the excision of encysted swellings of the eyelids, to remove any portion of the integuments, and he has cut away some tumours of this kind which were as large as a pigeon’s, or hen’s egg. The incision through the skin, he says, should be longer than the tumour, so as to facilitate the extraction of the distended cyst. ( B . 2, p. 613.) When it is not ad vise- able, for reasons above stated, to attempt to dissect out every particle of the cyst, Beer fills the cavity with lint, lets the wound suppurate, and if this plan is not sufficient, he applies stimulants and caustic. It is no- ticed by Sir Astley Cooper, that encysted tumours, at the outer canthus, are often dif- ficult of removal, on account of their extend- ing into the orbit, and being adherent to the periosteum. (Surgical Essays f Part 2 ,p. 241.) Professor Scarpa has strongly recom- mended making the incision for the extrac- tion of encysted swellings of the palpebraj, on the inside of these parts. But, as Mr. Travers correctly remarks, the swellings are often situated superficially, and loosely connected with the tarsus, in which case the operation should be done on the outside of the eyelid. The latter writer admits, however, that the cyst is often formed be- twixt the cartilage and the ligamentary, membrane which covers it, and, in his opi- nion, it is only when an intricate adhesion subsists, and the appearance of a white cir- cumscribed indentation is seen upon the everted tarsus, that the excision should be performed on the inside of the eyelid, by dividing the cartilage. Synopsis of Hit Dis- eases of the Eye , p. 357.) I shall conclude the subject of tumours with a few observations, delivered by Sir Astley Cooper, and Professor Langenbeck “ The removal of encysted tumours, (the first gentleman observes,) is not entirely unattended with danger. I have seen three instances of severe erysipelatous inflamma- tion succeed the operation of removing these swellings upon the head, and I believe it is owing to the tendon of the occipito- frontalis being wounded in the attempt to dissect them out whole ’ (Surgical, Essays, Part 2 , p. 241.) In the extirpation of tumours about the neck, Langenbeck adopts the following rules: he makes a free division of the in- * teguments, and dissects the muscles from the tumour which lie over it, but he avoids cut- ting through, or injuring them : in this man- ner the swelling is rendered more moveable. By the situation of the muscles, he is then enabled to know the place of the chief blood-vessels ; and on this account, he par- ticularly advises young surgeons to study myology with the greatest care As Lan Vot.iL 65 513 genbeck remarks, it is indeed an important advantage, after a muscle is exposed, to know vvliat vessels lie at its edges, or under neath it. Thus, the surtorius is a sure guide to the crural artery, arid the sterno- cleido-masloideus to the carotid. A surgeon who knows correctly the anatomy 9 ! the parts, will not be in danger of wounding unintentionally any large vessel. When the surface of the tumour has been cleared, but t lie base of it is yet firmly attached, Langenbeck commences the separation on the side which presents the 'east risk, that is, where the least considerable blood-vessels are, and thence he proceeds by degrees to- wards the most hazardous side. In favour of this method, lie offers the following con- siderations-: if. by chance) an artery requi ring a ligature should be cut, it can now be more easily secured, as the base of the tu- mour is already partly detached. The loos- ened swelling may also be drawn away from the large vessels with the hand, or a tenaculum. Langenbeck never introduces the knife deeply, when there are large blood vessels there, but pulls the swelling out- ward, and then divides the cellular sub- stance thus stretched, which is situated up- on the already exposed portion of the tu- mour. In this manner the swelling can al- ways be drawn more and more away from the vessels, until, at last, there is no danger of wounding them. By attending to these principles, Langepbeck has succeeded in re- moving many very large tumours from the neck, where nearly ail the muscles of that part were exposed in- the dissection, and the carotid denuded. After one of these ope- rations, not only the styloid process could be felt, but ail tne muscles, originating from it, could be distinctly seen. (Bibl. fur die Chir. B. 2, p. 312, fyc. 12 rno.Goliingen, 1808.) C. G. Slenlsei, De Sleatomatibm in prim ipio Aorta 1 , rc perlis et Cysticis in gen* re excrescen- tibus. lit!: sb. 1723. J. J. P.enck, JYovupi Sy sterna Tumoruni, quo hi morbi in sun ge- nera ct species rediguntur . Purs prior. I'P.mo. Vienna. 1767. lVui. Ogle., Letter concerning the Cure of Encysted and other kinds of Tu- mours with : at the Knife. 8 10 . Lend. 1754. Ph. Tr. Walther, aber die angebohrnen Fd thaulgeschmdsien mid and ere Bildungsjeh - ler. fol. Landshul. 1814. .< P. IV cidmanu , Annolatio de Siealomatibus 4to. Maguntiaci , 1817. JV. Hey, Practical Observations in Surgery, p 517, Eci 2, 8 vo. Land. 1810 Al- lan Bui us, Surgical Anatomy of the Head and Neck,8vo. Edin. ■ 1.81-1 : this work coi<,- tains much valuable in forma: ion , respecting the extirpation of swellings about the neck. Schreger Chirurgisrhe Versiiche . B. \ ,p. 297 ; Ueber Lipoma und Ex tir patio derselben. Svo. JVurubcrg. 1811, John Baron, An Inquiry, illustrating the nature of Tuberculoled Accre- tions 'of Serous Membranes, and the Origin cf Tubercles and Tumours in different textures of the Body $ko. Loud. 1819. Sir Astley Cooper. Surgical Essays, Part 2. C. J. ,W. Langenbeck , Bibl. far die Chir B. 2, p. 312. Gutt. 1808. Also, Gesrhichte einer gross en Speckgesehvjulst wehher mit deni Unterkiefer •14 ULCERATION so fcst zusanuneuliing , dass die Trennung mit dir Sage verrxchtel werden music : Neue Bibl. B. I, p. 295. 12mo. Hanover. 1817. B. H. Jacobsen, de Tumoribus Cysticis , 4 to. Jena , 3793. C. G. Ludwig Manila de cxscindcn- dis Tumoribus tunica inclusis, 4 io. Lips. 1758. TYMPANUM. For an account of its dis- eases, see Ear . u. i LCERATION, is the process by which sores or ulcers are produced in animal bodies. In this operation, the lymphatics appear to be, at least, as active as the blood- vessels. An ulcer is a chasm formed on the surface of the body by the removal of parts back into the system by the action of the absorbents. At first, it may be difficult to conceive how a part of the body can be re- moved by itself; but there is not more diffi- culty in conceiving this, than how the body can form itself. Both facts are equally well confirmed. When it becomes necessary that some whole living parts should be removed, it is evident, says Mr. Hunter, that nature, in order to effect this object, must not only confer a new activity on the absorbents ; but must throw the part to be absorbed into a state which yields to this operation. The absorption of whole parts in disease, arises from five causes; pressure : irritation of sti- mulating substances ; weakness; inutility of parts; death of them. ( Hunter on Inflam- mation, *c. p. 442 — 446.) Ulceration takes place much more readily in the cellular and adipose substance, than in muscles, tendons, ligaments, nerves, and blood-vessels. Hence, in the progress of pus to the surface of the body, ulceration of- ten takes a circuitous course for the purpose of bringing the matter to the skin. The skin itself, also, being highly organized, con- siderably retards the bursting of abscess- es. On the same account, when ulce- ration is spreading, the edges of the skin hang over the ulcerated surface. ( Hunter , p. 447.) New-formed parts, such as cicatrices, cal- lus, and all adventitious new matter, such as tumours, readily admit of being absorbed. The adventitious matter, indeed, is more prone to be absorbed than that which is a substitute for the old. Mr. Hunter explain- ed this circumstance on the principle of weakness. When ulceration takes place, in conse- quence of the death of an external part, it occurs first on the outer edge, between the dead and living substance. Abscesses constantly make their way to the surface of the body by ulceration ; but as some textures more readily admit of being absorbed than others, the matter of- ten follows a circuitous course, before it can arrive at the skin. ( Hunter , p. 448, 449.) A tumour, when it makes equal pressure in every direction around, will only make its wav in an external course, because what Mr. Hunter termed interstitial absorp- tion happens in n« other direction. (P. 449.) The parts which are situated between an abscess, or any extraneous substance, and the nearest surface, are those which are most susceptible of ulceration. This is one of the most curious phenomena connected with the process under consideration. It shows that there is a principle in the human body, by which parts are always prone to free themselves frbm disease. Slight pressure from without will often produce a thicken- ing of parts, and hence Mr. Hunter remarks, there even appears to be a corresponding backwardness to admit disease. ( P . 449.) Both these facts, he observes, are shown in the case of fistula lachrymalis ; for though the matter is nearest the cavity of the nose, still it makes its way externally, by means of ulceration, while the Schneiderian mem- brane even becomes thickened, so as to be- come a barrier against the progress of the disease inward. (P. 451.) There is one difference between the ad- vancement of an encysted tumour to the surface of the body, and the progress of an abscess in the same direction, viz that the former does not excite ulceration of the c> st : but an interstitial absorption of the sound parts between the cyst and skin, till the cyst and external skin come into con- tact, at which period inflammation takes place, and absorption becomes accelerated into ulceration. In an abscess, the progres- sive ulceration begins in the cyst, at the same lime that the interstitial absorption in the sound part covering the matter is going on. (P. 452—457.) The action of progressive absorption is to remove surfaces contiguous to irritating I causes, which Mr. Hunter referred to pres- sure, irritation, and weakness. In cases of tumours, pressure becomes a cause. The buttocks and hips of persons who lie long on their backs, often ulcerate. The heels of many patients, with fractures, who lie for a great while in the same position, are apt to ulcerate. In the latter instances, Mr. Hun ter conceived that ulceration is a substitute for mortification, and is at the same time, a proof of a certain degree of strength ; for if the patient’s constitution were very weak, the same parts would mortify. (P. 453.) That pressure is a frequent cause of ulcera- tion, is also evinced by the occasional ef- fects of chains on prisoners, and harness on horses. ULUEKS. 515 ihat irritating substances produce ulcera- tion, needs no illustration. Progressive absorption may occur either with or without suppuration. We have in- stances of the latter in cases of extraneous bodies, which travel about the, body with- out producing irritation enough to give rise to the secretion of pus. In the pro- gress of aneurisms of the aorta, and of fungous tumours of the dura mater to the sort ace, the same tact is also illustrated. (P. 455.) Absorption with suppuration, in other words, ulceration either happens in conse- quence of suppuration already begun, in which event the pus acts as pressure ; or else absorption attacks external surfaces from particular irritations or weakness, in which case suppuration must follow. (P. 45fl.) The production of ulceration requires much greater pressure from without than from within. The process is always dis- posed to take place more quickly, when near the surface of the body, and its progress be- comes accelerated in proportion as it arrives near the skin. The adhesive inflammation precedes the suppurative, and prevents the pus from be- coming diffused, as soon as it is secreted, and w hen the cyst afterward ulcerates, in order to let the matter approach the skin, the adhesive inflammation still continues to go before the ulcerative process, and thus pre- vents the matter from insinuating itself into the interstices of the cellular substance. (P. 457.) The pain of ulceration is, in some degree, proportioned to its quickness. When ulce- ration begins on a surface, or takes place for the purpose of bringing matter to the skin, the pain is always considerable. When ul- ceration takes place, in order to separate a dead part, as in sloughing, exfoliations, &c. there is seldom any particular pain. (P. 459.) The ulcerating sore always exhibits little cavities, while the edge ol the skin is scal- loped, and thin, at the same time turning a little out, and overhanging, more or less, the ulcerated surface. The face of the sore appears foul, and the discharge is very thin. When ulceration stops, the edges of the skin become regular, smooth, a little round- ed, or turned in, and of a purple colour, covered with a semi-traiispaivnt while. (Hunter on Inflammation, fyc. p. 460.) The reader, desirous of further informa- tiorijshuuld particularly consult this last pub- lication, and Professor Thomson's Lectures on Inflammation , p. 349, <§/-c. ULCERS. Surgeons usually define an ulcer to he a solution of continuity in any of the soft parts of the body, attended with a secretion of pus, or some kind of dis- charge. In the present part of this Dictionary, there will not be occasion to speak ot several kinds of sores, which have been treated of in other articles. (See Cancer, Scrofula, and Vene- real Disease.) Ulcers are divided into local and constitu- tional. As Professor Thomson has well ob- served, however, it is only within certain limits, that this distinction is well founded; for an ulcer, which is at first completely lo- cal, may in time affect the system, so as to become constitutional ; and ulcers which derive their origin from some general affec- tion of the system, may remain after the re- moval of the constitutional disorderly which they were originally produced. ( Lectures on Inflammation, p. 427.) “ Ulcers (sa\s Dr. Thomson) have usually been distinguished from each other by the causes by which they are induced, by the symptoms whi^h they exhibit, and by the parts of the body in which they occur. The wantof a disposition to heal in a suppurating surface may depend upon some specific action in the cause from which it proceeds, upon something peculiar in the constitution of the patient in whom it exists, or merely upon an improper mode of management : and hence, rhe distinction that has long been made of ill-conditioned -ores, or ulcers, into those which are specific in their nature, and into those which are simple. “ Specific sores, or ulcers, may be occa sioned by specific poisons, or by particular diatheses. The sores or ulcers which arise from specific poisons, may be either local, that is, confined, tike a primary syphilitic ulcer, to one spot ; or constitutional, that is, liable to occur in any part, texture, or or- gan, such as secondary syphilitic ulcers. Of diatheses, predisposing to ulcers, we have examples in the scrofulous, scorbutic, and arthritic diatheses, and also in the syphiloid diatheses, or that which arises not unfre- quently in those who have had syphilis, from the too tree and injudicious use of mercury. lt Every ulcer, strictly speaking, is of a local nature; but there are ulcers, which, though necessarily local iif their appearance, are connected with, or dependent upon, dis- eases, which affect the general system. These ulcers ought to be regarded as modi- fications of, or forms in which the diseases appear, with which they are connected. Considered in this light, it is obvious, that specific ulcers can be treated of with pro- priety, only under the head of the diseases to which they respectively belong. “ We call those sores, ulcers, simple, which do not appear to proceed from any specific disease, or morbid diathesis existing in the constitution of those, in whom they take place. They are usually solitary occurren- ces, and the consequences of accidental injuries, and improper modes of manage- ment. They may occur in every part of the body, but they appear most frequently upon the lower extremities.” Professor Thomson afterward remarks, that “ the appearances, which different ul- cers exhibit, seem, at first view, to afford an excellent foundation for distinctions. among them, and so they undoubtedly do in .manj; respects ” “ But (says he) it is to be regretted, that the characters, upon which the distinctions of ulcers, as well as of many other local diseases, are founded, are neither very uni- Gjnti in their appearance, nor are very easily distinguishable from one another. JNotonly are the local appearances which present themselves in simple ulcers liable to great variations in the different stages of the same ndividual affection,' but they are often ap- parently the same with, or at least not easily distinguishable from, those which occur in specific diseases, and which require for their cure peculiar modes of treatment. It is this circumstance, winch renders it so ne- cessary for us, in endeavouring to distinguish a. nl to cure ulcers, to avail ourselves of all the information, wuich we can procure from tiic history of the ulcer, from ihe nature ot the exciting cause, by which it lias been in- duced, and from ihe efiects of the remedies which have been employed, as well as from ihe particular. appearances, which the ulcer itself exhibits.” In noticing another ground of distinctions among ulcers, or that derived from the parts in -a hich they occur, Dr. Thomson observes that “ every texture and organ of the body possesses physical and vital qualities pecu- liar to itself ; and these qualities must neces- sarily modify the appearances), which each texture and organ respectively exhibits in the state of disease. Specific diseases ren- der some parts more liable than others to attacks of ulceration. Thus, secondary syphilis appears most frequently in the throat ; scurvy in the gums; cancer in the lower lip ; and lupous and scroiulous ulce- rations in the upper lip, or in the nose. Cancer seldom or never appears primarily • rt the upper lip ; but syphilis, when it at- tacks this part, puts on many of the appear- ances of cancer j” a fact, which Dr. Thom- son says he iirT.t.bmmsd from Mr. Pearson. (Bee Lectures *•;! 'Inflammation, p. 427 — 430 ) in the vikm'aie treatise on ulcers, publish* edvby Sir Everard Home, these complaints are divided into six principal kinds, viz. : 1. Ulcers in parts, which have sufficient strength to carry on the actions, necessary for their recovery. 2. Ulcers in parts, which are too weak for that purpose. ‘6. Ulcers in parts, whose actions arc too violent to form healthy granulations, whe- ther this arises from the state of the parts, or of the constitution. . 4. Ulcers in parts, whose actions are too indolent, whether tins arises from the stale of the parts, or of the constitution. 5. Ulcers in parts', which have acquired some specific action, either from a diseased state of the parts, or of the constitution. 6. Ulcers in parts, which are prevented from healing by a varicose state of the su- perficial veins of the upper part of thedimb. Ait hough I have chosen, in the subse- quent columns, to adopt this nomenclature, I am perfectly aware of its being on some accounts objectionable, but especially be- cause it assumes hypotheses, the truth of which can never be established, nor proved This is one of the considerations, which have induced Professor Thomson to prefer the old names usually applied to ulcers ; (Op. cit.p. 4 35, 438.) and he therefore treats of the simple purulent ulcer ; Inflamed ulcer ; F ungo us ulcer ; Callous ulcer ; Sloughing ul- cer ; Ulcerative ulcer ; Carious ulcer ; and Specific ulcers. or ULCEUS IN PARTS, WHICH HAVE SUFFICIENT STRENGTH TO CARRY ON TIIE ACTIONS NE- CESSARY FOR THEIR RECOVERY, SIMPLE PURULENT, OR HEALTHY ULCERS. Sir E. Home remarks, that in this species of ulcer, the pus is of a white colour, thick consistence, and readily separates from the surface of the sore, and when diluted, and examined in a microscope, is found to be made up of small globules, swimming in a transparent fluid. The granulations are small, florid, and pointed at the top. As soon as they have risen to the level of the surrounding skin ; those, next to the old skin, become smooth, and are covered with a thin, semi-transparent film, which after- ward becomes opaque, and forms cuticle. In the treatment ot this ki/id of ulcer, it is only necessary to keep the surface clean, and prevent the natural processes from being interrupted. Sir E. Horne observes, that this is in general best done by the applica- tion of dry lint, for the purpose of absorbing and retaining, the matter, which serves as a soft covering for the granulations, and by putting over the lint a pledget of any simple ointment, in order to hinder the matter from evaporating, by which means the dressings will not become adherent, and may be easily taken off, as often as requisite Although healthy ulcers require no medi- cated application to be made to them, the dressings must be such as do not disagree with the granulations, or surrounding skin. With some patients, a roller applied with moderate lightness* with a view of retaining the dressings, which cause uneasiness in the part, and make the ulcer lose its healthy appearance. Bir E Horne states, that he has seen several such cases, in which the proper appearance of the sore 'returned as soon as the bandage was discontinued. In some patients, ointment irritates and inflames the neighbouring skin ; and certain superficial ulcers will not heal, while kept in a moist state, and unexposed to the air ; but heal, when allowed to become dry and co- vered with a scab. Sir E. Home refers these particularities to constitutional causes, and not disease ; for the ulcers neal as soon as *the particular things, which disagree with them, are dis- continued. These peculiarities in certain healthy sores may also attend others of a dilferent description, and should always be discriminated from the effect* ot disease. Sir E. Home very judiciously recom- mends inquiring of patients, who have pre- viously had sores, what kind of applications they derived most benefit from, and what dressings were found to disagree. ULCERS. ■A1 TREATMENT. 1. Applications in the form of vapour, and fomentations, should never be employed, as they render the texture of the granulations looser, and diminish the disposition to form skin. 2. With respect to fluid applications, Sir E. Home also very properly condemns poul- tices, as well as fomentations. He speaks of alcohol, as being an application, which promotes the formation of a scab, when this mode of cure is chosen 3. in regard to ointments, their only use, in cases of healthy ulcers, is to keep the matter from evaporating. The most simple ointments are the best for the purpose ; par- ticularly the one composed of white wax and olive oil. Sir E. Home observes, that the great ob- jections to the common simple ointments are, that they sometimes disagree with the skin, even when recent a*nd free from all rancidity. When they have acquired the latter quality, they still more frequently create a greater degree of irritation. 4. With respect to applications in the form of powder. Sir E. Home remarks, that when it is desirable to form a scab on the ulcer, any inert powder mav be sprinkled on the sore; but he prefers dry lint. Nothing should touch the powder, or lint; and to prevent this circumstance. Sir E. Home re- commends applying a little bolster on each side of the sore, and over them a roller, which will go from one bolster to the other in the manner of a bridge. For healthy ulcers, dry lint is to be re- garded as being upon the whole the most eligible application. When the sore does not secrete pus enough in twenty-four hours to moisten the lint, the dressings are only to be changed every other day. When a moderately tight bandage is not forbidden by constitutional peculiarities, it is useful both in supporting the muscle? and skin, which are often in a flabby state from the unexercised state of the limb, and in de- fending the newly formed parts. (See Home on Ulcers.) ULCERS IN PARTS WHICH ARE TOO WEAK TO CARRY ON THE ACTIONS N ECESsAR V FOlT THEiR RECOVERY ; THE OVERACTING UL CERS OF MR. BURNS ; THE FUNGOUS ULCERS OF OLDER WRITERS. This is the second of the classes, into which Sir Everard Home has divided ulcers in general. The granulations of these sores are larger, more round on their external surface, and of a less compact texture, than those formed on ulcers in healthy parts. Sir E. Home has aiso noticed their semi-transparent ap- pearance. When they have filled up the cavity of an ulcer to a level with the surface of the body, they do not readily form skin, but, rising up in a still higher manner, often lose altogether the power of producing new mtis. When the parts are still weaker, the granulations sometimes continue gradually to fill up the hollow of the ulcer, and then, all on a sudden, are s iddenly absorbed, so as to leave the sore as deep as it was before. Ulcers may be weak from the firs% or be- come so in the progress of the case Even granulations of the most healthy kind, if they are not skinned over in a certain time, gradually lose their primitive strength. Sores on the legs are greatly under the in- fluence of all natural peculiarities of the constitution, and every thing which affects the health. When the constitution becomes in the least weaker or stronger, the appear- ance of the granulation becomes changed accordingly, and this effect of constitutional weakness , or strength on ulcers is greater, in proportion as the sores are further from the source of the circulation. V\ bile the constitution is undergoing anv kind of disturbance, the healing of an ulcer is suspended. Mental anxiety is very apt to retard cicatrization. Such effects of the constitutional kind ou ulcers are greater in weak and delicate per- sons, than in the strong and robust. Change of weather nas considerable influence over the healing of sores. Sir E. Home mentions in proot of this fact, that when there were several hundreds of uicers in' the Naval Hospital at Plymouth, in 177S, every time the weather changed from a dry to a moist state, the ulcers universally assumed an un- healthy appearance ; but put on a better as- pect when the weather became dry again. In the treatment of this kind of ulcer, tonics are to be exhibited, particularly bark and steel, and every thing which disagrees with the constitution is to be avoided. Wine and cordial medicines are also usually pre- scribed. Porter, however, is deemed better than wine for working people. bir E. Home observes, that the first ob- ject in the local part of the treatment, is to keep he granulations from rising above the edge of the surrounding skin. This gentle- man (jn my opinion) very judiciously repre- sents the greater propriety of preventing the granulations from ever becoming, loo high by the employment of proper applica- tions, than following the com -non plan of destroying the high granulations with es- char*. tics, after they have risen toa-i impro- per height. There cannot be the smallest doubt, that if the granulations could always be prevented from rising too much the pa- tient would suffer a great deal less pain. Instead of applying to the surface of the uic-rs, now uridr-r consideration, lunar caus- tic, blue vitriol, red precipitate, &e. bir E. Home prefers mixing these escbarotles with other substances, so us to render ihem only strong stimulants; ami using them in this latter torm. He conceives, that when toe high granulations are destroyed with escharotics, the disposition of iht- surface underneath to reproduce them is increased, but that this is not the case when the luxuri- ant parts me only stimulated, so as to be come absorbed. The same gentleman seems to think, that ULCERS. G18 when animal substances grow with great ra- pidity. the) are, like vegetable ones, weaker than when produced in a slower manner. Hence Sir E. Home is of opinion, that the growth of granulations ought to be cheeked in the early stage of their formation, by some resistance which they are just able to over- come, under which circumstances they de- rive strength from the limited increase of ac- tion which they are obliged to undergo. On the same principle, according to Sir E. Home, the pressure of tight bandages is advantageous, and ulcers which heal while the patient is vv Iking about* are not so apt to break out again as others healed while the parts are in a state of perfect rest. In the treatment of these ulcers, when the granulations have come to a proper height, and do not form k thm, semi-transparent pelli- cle upon their surface, they are t<- be consi- dered as weak parts, and treated according- ly. Sir E. Home tlouks, that in this circum- stance, the best plan, when no particularity of constitution forbids, is pressure, made with a thin piece of lead over the dressings, and supported with a tight bandage. OF APPLICATIONS TO ULCERS ATTENDED WITH WEAKNESS. Although strictly we have no topical ap- plications which can directly communicate strength to granulations, there are certainly some which prevent the granulations from exhausting themselves by luxuriant growth, and stimulate them to draw more blood from the arteries ; which effects, as Sir E. Home remarks, render such granulations stronger. 1. This gentleman very properly con- demns, as applications to w r eak ulcers, all relaxing fomentations commonly employed ; and recommends, instead of them, the use of spirits of wine, and the decoction of pop pies, in equal proportions, not, however, to be applied hot. 2. Wuh regard to moist applications, the same gentleman expresses his disapprobation of poultices, and mentions a weak solution of the argentum nitratum. as the most eligi- ble application in an aqueous form. 3. On the subject of powdered substances, as applications to weak ulcers, SirE. Home says, be has often tried bark, and the lapis ca- laminaris, without perceiving that the former had any power of strengthening granulations, or the latter any virtue in disposing them to form new 7 skin ; properties commonly im- puted to these applications. Sir E. Home entertains no better opinion of plaster of Paris, or powdered chalk, em- ployed w ith a view of promoting the forma- tion of skin. Powdered carbon he speaks of as being more adapted to irritable, than weak ulcers. He praises powdered rhubarb, as particularly applicable to the latter kind of ulcer, because it represses the luxuriant growth of the granulations, renders them small and compact, and disposes them to form skin. When, however, the granulations have arisen above the level of the skin, it is not powerful enough to reduce them. When the rhubarb is too stimulating, it is to be mixed with a fourth part of crude opium in powder. A piece of lint, a little less than the sore, is always to be put over the powder, and co- vered with a pledget of simple ointment. 4. Ointments, according to Sir E Home, are particularly apt to disagree with weak ulcers. When other applications fail, how- ever, greasy ones must be tried, and the above gentleman gives a preference to the ung. hydrarg. nitrat. mixed with hog’s lard,, in the proportion of one to live, or else to common cerate, blended with a small quanti- ty of the hydrarg. nitrat. ruber. OF ULCERS IN PARTS, WHOSE ACTIONS ARE TOO VIOLENT TO FORM HEALTHY GRANU- LATIONS, EITHER FROM TH1 STATE OF THE PARTS, OR THE CONSTITUTION : SIM- PLE VITIATED ULCERS OF MR. B. BELL. There are three states of the constitution influencing the nature of ulcers ; an .irrita- ble state, in which aJI the actions of the ani- mal economy are more rapid than in health ; an indolent state, in which they are unusual- ly languid ; and, lastly, a diseased state, by which they are affected. An irritable and an indolent ulcer cannot in general be distinguished from each other by mere appearances, though they may be so in a few instanc s. Sir E. Home informs us, that the disposition of an ulcer, like the disposition of a constitution, can only be ac- curately ascertained by determining the ac - tions which arise from the different impres- sions made upon it. The same gentleman notices, that the fol- lowing appearances at once show the ulcer to be of an irritable kind. The margin of the surrounding skin being jagged, and ter- minating in an edge, which is sharp and un- dermined. The bottom of the ulcers being made up of concavities of different sizes There being no distinct appearance of gra- nulations, but a whitish spongy substance, covered with a thin ichorous discharge. Every thing th»t touches the surface gives pain, and very commonly makes it bleed. The discharge is altered from common pus to a thin fluid, in proportion to the degree of irritability communicated to the sore by con- stitutional causes: The pain of an irritable sore in general gradually becomes less. When it is not con- stant, but comes on in paroxysms chiefly in the evening, or night-time, with great vio- lence, convulsive motions of the limb arc apt to occur, and extend to various other parts. Sir E. Home refers this symptom to irritation, communicated along the course of the nerves, and producing an action in them, attended with a violent contraction of the muscles, which they supply. When the above-mentioned signs of an ir- ritable ulcer are not present, we must ionn a judgment, of the nature ot the sore irorn listening to the history of the case, the effects of various applications. &c. When this kind ULCERS. of information cannot be obtained, Sir E. Home recommends the treatment to begin on the supposition of the ulcer being of an irritable nature. When an ulcer occurs just over the mal leolus externus, it is generally of an irritable kind, in consequence of the nature of the part on which it is situated, quite inde- pendently of any constitutional or local disposition to irritability. Sir E Home conceives, that the periosteum, which here, lies immediately under the skin, becomes the seat of the ulcer, is the cause of its being very difficult to heal, and gives it the irrita- ble appearance. The fact that sores, situa- ted on the ligament of the patella, and over the periosteum of the anterior surface of the tibia, assume a similar appearance, and are equally difficult to heal, made the above gen- tleman more confbmed in his sentiment. In treating ulcers in general, the surgeon will find it exceedingly advantageous to be acquainted with the effects of a great many external applications ; lor a very few cases will continue to heal beyond a certain time, without some alteration in the treaunent. The necessity of changing the applications, after they have been continued for a certain time, is strikingly illustrated by the fact, (bat leaving off a powerful application, and em- ploying one which at first would have had no effect, often does a great deal of service. When the change is made to a medicine of powers equal to those of the previous one, the benefit will be more lasting than in the preceding circumstance. Sir E. Home compares the principle of this occurrence with that by which change of air, even of a very salubrious air, for one that is less so, often produces an infinite im- provement of the health. OF APPLICATIONS TO IRRITABLE ULCERS. I. SirE. Home recommends applications in the form of vapour as being particularly useful, by their quality of allaying irritation and soothing pain. The steam of warm water is productive of benefit in this way, though seldom u>ed by itself. Its good effects are increased when it is mixed with spirits. Sir E. Home speaks also in favour of the benefit derived from fomentations contain- ing opium ; such as the tincture of opium sprinkled on flannel, wrung <>ut of warm water ; or the application of flannels, wet with a warm solution of the extract of opi- um, or with a decoction of poppy heads. A decoction of chamomile flow ers, the tops of wormwood, or hemlock leaves, may also be employed lor the same purpose. Sir E. Home points out particular irrita- ble ulcers, however, which are rendered more painful by warm applications ; and he states, that the sores alluded to are generally attended with a mottled purple discolora- tion of the limb for some way from them, and a coldness of the low'er part of the leg, and that they are often disposed to mortify, which event is promoted by warmth. 2. As for moist applications, lb© poultice made of linseed meal is the rnoSt simple, and most easily made ; and as it does not neces- sarily require any addition of oil, is to be. preferred, when this disagrees with the sore. Sir E. Home does not say much in favour of the use of the extract of lend in pouhices ; for though he allows that ii often answers very well, he adds, that it also frequently disa- grees with the ulcer, and, if long used, is apt to bring on the lead-colic. A decoction of poppy -heads is said to be a very good liquor for making poultices. The carrot poultice is also found to agree with a great many irritable sores. fhe great objection to poultices in these cases being the weight of such applications, the limb should always, if possible, rest upon the poultice, and not the poultice upon the limb. When the weight cannot be avoided, and is hurtful, a lighter application should be chosen. If poultices be employed, their use is to be continued as long as the granulations are small, and the ulcer is rapidly diminishing in size, and this even till the cicatrization is complete. When the granulations become large, and loose in their texture, poultice, should be left off. When the weight of poultices prohibits their use, Sir E. Home advises the trial of lint, dipped in one of the following lotions, and covered w ith a pledget of some simple ointment : a solution of the extract of opi- um ; a decoction of poppies ; the tincture of opium ; a decoction of cicuta ; the liquor plumbi acetatis dilutis ; or a weak solution of the argentum nitratum. 3. Powdered applications are generally too stimulating for irritable ulcers. Carbon has been found useful ; so has powdered ex- tract of opium, mixed w ith an equal quantity of carbon, or linseed flour. How ever, opium occasionally affectsthe constitution, in conse- quence of absorption, and it has been known to excite violent inflammation, ending in mori ideation. 4. Ointments are not often proper appli- cations for irritable ulcers, as they are always more or less rancid, and generally disagree with the skin of persons most subject to such diseases. Sir E. Home mentions cream as being a very useful application, particularly in cases in which warmth is found to do harm. The same gentleman recommends, as a substitute for it ; an ointment composed of hog’s lard, purified by being repeatedly washed in spring water, and then mixed with a small quantity of white wax and rose water. The observations made respecting the so iutions of lead, apply to the unguentum ce- russse acetalaj. 5. The pressure of bandages is generally hurtful to irritable sores, though a slight de gree of it proves serviceable to certain ulcers, which are somewhat less irritable, and arise from weakness. OF ULCERS IN PARTS, WHOSE ACTIONS ARE TOO INDOLENT TO FORM HEALTHY CPA- ULCERS. m NULATIONS, WHETHER THIS INDOLENCE ARIt .£g' FROM THE STATE OF THE PARTS, on of THE constitution: THE callous ulcers of several writers. Surii is the next division of ulcers adopt- rd by Sir C. ilorne, in his treatise on the subject The indolent ulcer terms in its apoearance'a complete contrast to the ini- tlble one. Tiie edges of Hie surrounding ski,, are thick, prominent, . smooth, and rounded. The surface of tire granulations is smooth and glossy. The pus, ...stead of being of a perfect kind, is thin and watery, being composed of a mixture of pus and coagulating Ivinph. The lymph consists of flakes, which cannot be easily separated from the surface of the sore. The bottom cf the ulcer forms quite a level, or nearly n? fbo odT circumstance of some indolent sores having, the appearance of irritable ones, is, in some degree, explained by ul- cers always being influenced by changes in the constitution, and accidental cncum- stances' affecting the parts Most of the ulcers, which are to be seen in the Londop hospitals, are ot the undo ept S ind An indolent disposition m the ulcer may proceed altogether from the long ex- istence of the disease; and hence, >~ir L. Home very justly observes, it is immaterial “Xer atWh was healthy, weak, or irritable, for, if not cured within a ccitaiu . ; m P ;+ becomes indolent, with the excep- of a few of the irritable kind, which never change their nature. Indolent sores do form granulations; but tUf.se C verv now and then, are all on a sud- wCbld, and, in the course oi four and twenty hours, the sore becomes as much incieasc.i in size, as it had been d - i finished in as nnr.iiy days, or weeks. 1 » ahsorptiou of the granulat ions .arise* princi- pally iro;n their not being o t a healthy biitd : but the event is promoted by changes in the weather, anxiety . fatigue, fcc ; The object in the tre.-ti.ucnt ot indolent v leers is nos simply to produce a cure, but in wider such erne r, permanent as po.‘- jujje* This cart only be accomplished by alterin 0 ' the disposition of the granulations^ and rendering them strong enough to stand their mound after the ulcer is tilled up When an ulcer,, wbu n lms existed six months is dressed with poUH.ces for a vvee , the granulations, at the end of tm. In ‘ , .vill partfv have filled up the hollow of tl- sore, but they will present a large, loose, and glossy appearance. Should the poul tice be now discontinued, and some proper stimulating application used for another week, the granulations will be found, at the expiration of this time, to have become smaller, more compact, redder, and free from the glossy appearance. The ulcer, when healed by the latter application, will not be so likely to break out again, as when healed with large> loose, flabby, glossy gra- nulations. $ * Sir E. Home states, that the number of indolent sores, which heal under the use of stimulating applications, and do not break out agaju, compared with similar cases, treated with mild dressings, are as four to one. AFFLIC A.TIONS TO INDOLENT ULCERS. 1. Medicines in the form 521 of diluted nitrous acid to the bone removes, the earthy part, and excites the absorbents to act upon the remaining animal portion. 3. The only application, in the form of powder, adapted to indolent ulcers, is, ac- cording to Sir E. Home, the hydrargyrum nitratus ruber. It may be occasionally used for ulcers of the most indolent kind. 4. Ointments are represented as being particularly good applications for indolent sores. Ihe idea of the air having bad effects on sores, which are exposed to it, is now dis- believed. That air lias no irritating pro- perty of this kind is proved by the fact, that, when the abdomen of an animal is filled with it, no inflammation is excited. When the cellular membrane is loaded with it, in cases of emphysema, the parts do not afterward inflame. Nor do ulcers in the throat, as Sir E. Home justly remarks, heal less favourably than others, although they are of necessity always exposed to the air. Whatever ill effects arise, may probably be explained by the consequences of evapo- ration, which converts the soft pus into a scab. The granulations are, in all probabi- lity, most favourably circumstanced when they are covered with their own matter, which should only be now and then re- moved, in order that such applications may be made as will stimulate them to secrete a more perfect pus. F rom what has been just stated, it must be obvious that indolent ulcers should not be frequently dressed, and that if they are so, and the dressings are stimulating, the practice will do harm. Changing the dressings once in twenty-four hours is deemed quite sufficient, unless the quantity of matter be very great, which, seldom happens. One part of the unguentum hydrargyr’f nitrati, mixed with three of hog’s lard, is one of the best applications. Its strength, however, must be increased after being used for some time, as a dressing for th& same ulcer. The unguentum hydrargyri nitrati has the- effect of quickly removing the thickness of the edges of indolent ulcers, and the sur- rounding dark red colour of the skin. It seems also to have particularly great power in making the granulations become small and healthy, and, of course, the ulcer less likely to break out again. With some ulcers, however this ointment is found to disagree. The unguentum resinoe flavae, and the un- guentum elemi, mixed with the balsam of turpentine, or that of copaiba, are other common applications to indolent sores Sir E. Horne states, that the resins and turpen- tines are not so powerful as the acids and metallic salts in giving the granulations a healthy appearance, and a disposition to re- sist being absorbed. Cases, attended with a degree of indolent thickening, are sucli as are most likely to be improved by camphorated ointments. In numerous crises, the applications, what- ever they are, soon lose their effect', anil ULCERS. Sm- others should then he substituted for them. The past and present states of the sore are always to be considered. Although the ulcer may be in its nature indolent, it is liable to temporary changes from constitutional causes; and hence a temporary alteration in the treatment becomes proper. 5. Bandages are undoubtedly of the most essential service in healing many hinds of ulcers ; but their efficacy is so great in cur- ing numerous indolent sores, that they are sometimes considered the principal means of cure. But among modern advocates tor rollers Mr. Whately is one of the most zea- lous. While this gentleman acknowledges that the efficacy of pressure in counteract- ing the effects of the dependent posture was known to Wiseman, who recommended the use of the laced stocking for this purpose, he conceives that the effects of pressure, in the cure of ulcers on the extremities, pre- viously to the appearance of Dr. Under- wood’s treatise, were not duly insisted upon by surgical writers. However, he confesses, that there always have been practitioners, who were acquainted with the importance of this mode of treatment, and adopted it in their practice. He then criticises the work of Sir Everard Home, in which, it is re- marked, that the effect of pressure is not much relied upon for the cure of these com- plaints. Indeed, says Mr. Whately, it is stated in that book, not only that no benefit is derived from compression in several spe- cies of these ulcers, but that many ulcers are rendered worse, more painful, and more unhealthy in their appearance by its use ; -truths which it would be impossible for Mr. Whately to refute. They are, 1 conceive, admitted by himself, when he observes that there are certain conditions of an ulcer which will not bear compression. Whether Sir Everard Home has not given a suffi- ciently favourable account of the effects of pressure in the cure of ulcers of the leg, ! will not presume to determine. Perhaps he may' not have insisted so much upon this treatment as it deserves ; but I can find no fault with him for speaking of it as frequent- ly injurious, because the fact is notorious. In the cases, published in Mr. Whately’s essay, very little variety of dressing was used ; pressure being the principal means of cure, with some exceptions particularly specified in the work. I cannot doubt (says Mr. Whately) that the practice here recommended must in the end, prevail, notwithstanding it has this great obstacle to contend with, that surgeons must condescend, for the most part, to ap- ply the bandages with their own hands. The clumsy and ineffectual manner, in which this business is too frequently done, can never be expected to produce the desired effect. 1 am certain, that if the necessary pains be taken, according to the directions here laid dowu, such effects will uniformly follow, as must convince the unprejudiced mind, that to have recourse to the operation of tying varicose veins, and the application of a great variety of remedies, can be i^ery rarely, most probably never necessary. I can safely de* clare, that all such cases as are described by Sir E. Home to be cured by this operation^ have readily yielded under the proper ma n age merit of pressure alone.” With respect to Mr. Baynton’s mode of treatment, while Mr. Whately regards it as a confirmation of the principles insisted upon in his own tract, he considers the plan of making the pressure with adhesive plas- ter inconvenient, and on several accounts objectionable. In every case related by Mr. Baynton, he is sure that the proper ap- plication of compresses and fiannel rollers, would have produced similar good effects. The instances of success by this method, after the supposed failure by the roller, he attributes to the pressure made with the plasters, having beer; applied with Mr. Bayn- ton’s own hands, whereas that with the roller was probably so made, that the effect intend- ed by it could not possibly be obtained. No surgeon, he observes, who will not be at the trouble of applying the roller and compres- ses himself, can be a judge of what maybe effected by the proper management of them. The following is the calamine cerate, which Mr. Whately has usually employed, f^. Axung. Porcin. depur. lib. iij. Empl PI umbi. lib. iss. Lap. Calarn. preep. ap. lib. j. M. “To this formula, (says Mr. Whately) I shall add another for making a cerate, which nearly resembles the unguentum tripharrai- emu of the old Dispensatory, but being less oily, it makes a much more adhesive plas- ter. It should be spread on rag, or silk, as an external covering to the dressing on lint, where a tow plaster cannot be conveniently used, as in wounds of the face or hands, a bubo, or any other sore, where an external plaster cannot be readily retained in its si- tuation by a bandage. This plaster is like- wise so mild, that it never irritates the skin. I have found it also a very useful plaster in fractures. The following is the formula : j^. Empl. Plumbi lib. j . Axung. Porcin depur. unc. vj. Aceti unc. iv. M.” With respect to the proper method of ap- plying the roller and compresses, Mr. Whately offers the following remarks : “ The best width for a Hannel roller, de- signed for those who have slender legs, is three inches; but for those whose legs are of a large size, they should always be three inches and a half in width. They must therefore be at first lorn a little wider, that they may be of their proper width when repeatedly washed. It will likewise be found, that rollers made of fine, soft, and open flannel, will answer much better than those made of coarse or hard fiannel. “ For those who have full-sized legs, the length of six yards is but just sufficient to answer all the purposes intended by a roller ; but in those who have very small legs, five yards is a sufficient length. Care should he taken that the rollers be washed in very hot water, and they should be hung up to dry immediately on being washed. II these pre ULCERS. cautions be not attended to, repeated wash- ing them will, in some kinds of flannel, make them as narrow as tape, by which they will be rendered almost useless. They should be often washed, as they are much softer, and of course sit easier, when quite clean than when they are soiled. “ In applying a roller, (says this gentle- man) the first circle should be made round the lowest part of the ankle, as near as possible to the heel; the second should be formed from thence round the foot; the third should be passed again round the foot quite to the toes The roller should then be passed from the foot round the ankle and instep a second time to make the fourth cir- cle. In doing this, it should be brought nearer (but not over) the point of the heel than it was at the first time of going round this part. The fifth circle should pass over the ankle again, and not more than half an inch higher up (he leg than the fourth cir- cle. The sixth, seventh, eighth, and ninth circles should ascend spirally along the small of the leg, at the exact distance of three- fourths of an inch from each other. Ha- ving proceeded thus far up the leg, we may begin to increase the distances of the circles from each other : they may succeed each other upward to the knee at the distance of from one to two inches, according to the size and shape of the !e^. At that part where the calf of the leg commences, it is generally necessary to let the upper edge of the roller be once, twice, s or thrice turned downwards for about half the circumference of the leg, in order to make the roller lay smooth between the middle of the calf and the small of the leg. When the roller has been thus applied as far as the knee, there will be a portion of it to spare, of perhaps a yard in length ; this remainder should be brought down by spiral windings, at greater distances from each other than those which were made on the ascent of the roller. The windings should in general be completed in the small of the leg, where the roller should lie pinned. “In many cases, it is necessary to apply the roller over the keel. It should be brought as low as possible round the ankle ; as in the , former description. From thence, the se- cond circle of the roller should pass from the instep over one side of the heel, and be brought over the other side of the heel to the instep again. The third circle should be passed round the ankle a second time, but stili nearer to the heel than the first cir- cle was. The roller should after this be brought back to the foot, and passed round it to make the fourth circle. A fifth circle should be again made (though it is not in all cases absolutely necessary) round the foot, to the toes. To make the sixth circle, the roller should be brought back, and passed round the ankle again. The seventh, eighth, ninth, tenth, and eleventh circles should ascend spirally at the exact distance of three- fourths of an inch from each other ; these distances commencing at the sixth circle. The roller should then be carried to the ■m knee, and be brought , flown -again to the small of (he leg, as described in the former instruction. “ In applying the compresses, it is neces- sary in every instance to put them on one by one, and not all in a mass, though they be of a proper size and number. They should be crossed in different directions ; the largest ot them should in no case be longer than just lo meet on the opposite side of the leg to which they are applied. I have in many instances seen the compresses applied by the patients of such a length as to go round the. leg like a roller, and be fastened together with pins. This met hod generally wrinkles and blisters the skin; and by no means answers tin 1 purpose of making a com- pression on the part where it is most want- ed. I never suffer a pin to be used in (he compresses. If the same compresses in a tty case be applied two days together, they should always be turned on the contrary side at each reapplication, in order to pre- vent wrinkles on the skin.” Mr. Whately notices two objections* made by Mr. Baynton to rollers. “ The first is, that it is difficult to retain the roller on the parts to which it is applied ; the second is, that it gives pain to the patient.' ” Mr. Whately’s experience, however, warrants him in saying, that a flannel roller will, in almost every instance, keep the exact posi- tion in which it was first placed, for a much longer time than is necessary. “ I have seen these rollers (says Mr. Whately) many hundred times keep their situations without any variation whatever for two days ; and that too without the least restraint ujaon ex- ercise. This has happened in those cases where, from the distance of the patient, or from the circumstance of his being nearly- cured, l have wished to dress the leg only every forty-eight hours. I must go a step further, and observe, that I have seen re- peated instances in which these rollers have remained in their situation for three or four days, and even nearly for a week without being applied afresh. In short, it is one of the best properties of a flannel roller, that it. is easily retained in its situation when well applied. In every instance in which it is necessary to use one, I could pledge myself to apply it in such a manner, as should pre- vent its altering its position for two days. The method I should use, I have already described ; in addition to which nothing more would be necessary, even in those cases where the shape of the leg is peculi- arly unfavourable to the retention of a ban- dage, than the insertion of a few pins. “ In answer to the second objection, I observe, that I have invariably found, that when a flannel roller has been applied in the manner here described, and has not been drawn unnecessarily tight, it gives no pain. It sits nearly as easy as a common stocking, and allows a very free motion and exercise of the limb.” (See Practical Observations on the Cure of Wounds and Ulcers on the Legs t ivithout rest ; by Thomas Whately , 1799.) 6. I shall next introdnee an account of £24 V) LCKIi< Mr. Baynton s p*lau of curing old ulcers of ihe leg, by means of adhesive plaster. Were 1 to say, that any particular method of dressing such sores is entitled to superior praise, 1 should certainly decide in favour of this gentleman’s practice. I have seen it most successful myself, and I h ins it highly spoken of by numerous professional frie. ids, in whose unprejudiced judgment i place much reliance. Mr. Baynton acquaints us, that the means proposed by him will be found, in most in- stances, sufficient to accomplish cures in the worst cases, without pain or confine- ment. After having been repeatedly disap- pointed in the cure of old ulcers, Mr. .Baynton determined on bringing their edges ' nearer together by means of slips of adhesive plaster. To this he was chiefly led, from having frequently observed, that the proba- bility of an ulcer continuing sound, depend- ed much on the size of the cicatrix which remained after the cure appeared to be ac- complished ; and from well knowing that the true skin was a much more substantial support and defence, as well as a better co- vering than the frail one, which is obtained by the assistance of art. But when he had recourse to the adhesive plaster, with a view to lessen the probability of those ulcers breaking out again, he little expected that an application so simple would prove the easiest, most efficacious, and most agreea- ble means of treating ulcers. Although the first cases in which Mr. Baynton tried this practice, were of an un- favourable nature, yet he had soon the sa- tisfaction to perceive that it occasioned very little pain, and materially accelerated the cure, while the size of the cicatrices were much less than they would have been, had the cures been obtained by any of the com- mon methods. At first, however, the success was not quite perfect ; as, in many instances, he was not able to remove the slips of plaster, with- out removing some portion of the adjacent skin, which, by occasioning a new wound, proved a disagreeable circumstance in a part so disposed to inflame and ulcerate, as that in (he vicinity of an old sore. He therefore endeavoured to obviate that in- convenience by keeping the plasters and bandages well moistened with spring-water, for some time, before they were removed from the limb. He had soon the satisfaction to observe, that the inconvenience was not only prevented, but that every succeeding case justified the confidence he non' began to place in the remedy. He also discover- ed, that moistening the bandages was attend- ed with advantages which he did not ex- pect : while the parts were wet and cool, the patients were much more comfortable, and the surrounding inflammation was soon- er removed, than he had before observed it to be. By the mode of treatment here recom- mended, Mr. Baynton found that the dis- charge was lessened, the offensive smell Ye moved, and the pain abated in a very- short time. But, besides these advantages, he also found that the callous edges were in a few days level with the surface of the sore ; that the growth of fungus was pre- vented, and the necessity of applying pain - ful escharotics much lessened, if not entirely done away. Mr. Baynton gives the follow- ing description of his method. The parts should be first cleared of the hair, sometimes found in considerable quan- tities upon the legs, by means of a razor, that none of the discharges, by being retain- ed, may become acrid, and inflame the skin, and that the dressings may be remo- ved with ease at each time of their renewal, which, in some cases where the discharges are very profuse, and the ulcers very irrita- ble, may perhaps be necessary twice in the twenty-four hours, but which I have, in every instance, been only under the neces- sity of performing once in that space of time. u The plaster should be prepared by slowly melting, In an iron ladle, a sufficient quantity of litharge plaster, or diachylon, which, if too brittle when cold, to adhere, may be rendered adhesive by melting half a dram of resin with every ounce of the plaster: when melted it should be stirred till it begins to cool, and then spread thinly upon slips of smooth porous calico^ of a convenient length and breadth, by sweep- ing it quickly from the end held by the left hand of the person who spreads it, to the other, held firmly by Another person, with the common elastic spatula used by apothecaries ; the uneven edges must be taken ofF, and the pieces cut into slips about two inches in breadth, and of a length that will, after being passed round the limb, leave an end of about four or five inches. The middle of the piece so prepared is to be applied to the sound part of the limb, opposite to the inferior part of the ulcer, so that the lower edge of the plaster may be placed about an inch below the lower edge of the sore, and the ends drawn over the ulcer with as much gradual extension as the patient can well bear; other slips are to be secured in the same way, each above and in contact with the other, until the whole surface of the sore and the limb are completely covered, at least one inch be- low, and two or three above the diseased part. il The whole of the leg should then be equally defended with pieces of soft calico, three or four times doubled, and a bandage- of the same, about three inches in breadth, and four or five yards in length, or rather as much as will be sufficient to support the limb from (he toes to the knee, should be applied as smoothly as can be possibly per- formed by the surgeon, and with as much firmness as can be borne by the patient, being first passed round the leg at the ankle joint, then as many times rotnid the foot ns will cover and support every part of it, ex- cept the toes, and afterward up the limb till it reaches the knee, observing that each turn of the bandage should have its lower ULCERS edge so placed as to be about an inch above the lower edge of the fold next below. “ If the parts be much inflamed, or the discharge very profuse, they should be well moistened, and kept cool with cold spring- water, poured upon them as often as the heat may indicate to be necessary, or per- haps at least once every hour. The patient may take what exercise he pleases, and it will be always found that an alleviation of his pain and the promotion of his cure will follow as its consequence, though under other modes of treating the disease, it aggra- vates the pain, and prevents the cure. u These means, when it can be made convenient, should be applied soon after rising in the morning, as the legs of persons affected with this disease are then found most free from tumefaction, and the advan- tages will be greater than when they are applied to limbs in a swollen state. But at whatever time the applications be made, or in whatever condition the parts be found, I believe it will always happen that cures may be obtained by these means alone, except in one species of the disease which seldom occurs, but that will hereafter be described. The first application will some- times occasion pain, which, however, sub- sides in a short time, and is felt less sensibly at every succeeding dressing. The force with w'hich the ends are drawn over the limb must then be gradually increased, and when the parts are restored” to their natural state of ease and sensibility, which will soon happen, as much may be applied as the ca- lico will bear, or the surgeon can exert ; especially if the limb be in that enlarged and compressible state which has been de- nominated the scorbutic, or if the edges of the wound be widely separated from each other.” Mr. Baynton afterward takes notice of the breaking of the skin near the ulcers ; a circumstance which sometimes proved trou- blesome, and arose partly from the mecha- nical effect of the adhesive plasters, and partly from the irritating quality of the plaster. Mr. Baynton, however, only con- siders such sores of serious consequence when they are situated over the tendon of Achilles, in which situation they are some- times several weeks in getting well. This gentleman recommends, with a view of preventing these ulcers, a small shred of soft leather to be put under the adhesive plaster. Mr. Baynton next adds, “that cures will be generally obtained without difficulty by the mere application of the slips and band- age ; but when the parts are much inflamed, and the secretions great, or the season hot, the frequent application of cold water will be found a valuable auxiliary, and may be always safely had recourse to where the heat of the part is greater than is natural, and the body free from perspiration.” (See •fl Descriptive Account of a new Method of treating old Ulcers of Ike Legs. Edit. 2, I; 1799.) ft ne circumstance, strongly in favour of 520 the advantages of the foregoing mode of treatment deserves particular notice: when M. Roux lately visited the London Hospi- tals, he had for the first time an opportunity of seeing this practice, which had never been tried in France. The plan appeared to' him so different from every thing which, he had been accustomed to see in his own country, where ulcers were almost alwavs treated by rest in an horizontal posture, and emollient applications, that he left London somewhat prejudiced against the new me- thod. Subsequently to his return to Paris, however, he has given it a fair trial, and experience has now entirely changed his opinion,- as he has had the candour to ac- knowledge. (See Relation d’un Voyage fait a Londres en 1814, ou Par allele de la Chi - rurgie Angloise avec la Chirurgie Francoisr it par P. J. Roux, p. 159.) OF ULCERS ATTENDED WITH SOME SPECIFIC DISEASED ACTION, EITHER CON5TITC- TIOSAL, OR LOCAL. 1 . Ulcers which yield to Mercury. Here we shall exclude from considera- tion venereal ulcers, as this subject is treat- ed of in the article Venereal Disease. At present we shall only notice such sores as are produced by other diseases of the gene- ral system, or of the parts, aud are capable of being cured by mercury. Perhaps there is no greater source of error in the whole practice of surgery, than the supposition that a sore, when it yields to mercury, must be of a syphilitic nature. Surgeons, however, who run into this ab- surdity. can hardly be imagined to be una- ware that so potent a medicine must have effects on numerous diseases of very differ- ent descriptions. Sir E. Home accurately remarks, that many ulcers unconnected with the venereal disease, which receive no benefit from other medicines, heal under a mercurial course, or yield to mercurial ap- plications. Insome cases, the ulcer remains in the same state, w hile mercury is used : but begins to look better as soon as the me- dicine is discontinued, in consequence of the beneficial change produced in the sys- tem by the mercurial course. In these cases mercurial frictions are the best, be- cause they occasion least impairment of the constitution, in consequence of the stomach continuing undisturbed, and capa- ble of digesting welt. Another description of ulcers, noticed by SirE. Home as derivingbenefit from mercu- ry, occur on the instep and foot, have a very thickened edge, and are attended with a dis- eased state of the surrounding skin, so as to bear some resemblance to elephantiasis. They are frequently observed affecting ser- vants who live in opulent families in an in- dolent and luxurious way. Sir E. Home states, that fumigations with hydrargyrus' sulphuratus ruber heal these ulcers, and re- solve in a great degree the swelling of the surrounding parts. In some instances, an ointment of calomel and hog’s lard : In b26 ULCERS. others, the camphorated weak mercurial ointment, is the best application. Many diseased ulcers, particularly those of a superficial kind, with a thickened edge, may be healed when they are dressed with a solution of one grain of the hydrargyrus muriatus in an ounce of water containing a little spirit. heals, while the skin beyond is in a slate of ulceration. 2. Ulcers curable by Hemlock. Sir E. Home places more reliance on hemlock as. an external than an internal remedy for ulcers. The ulcers which usually receive benefit from hemlock applications, look like those of an irritable sort ; but the surrounding parts are thickened in conse- quence of some diseased action. Such sores occur near the ankle, which joint is at the same time enlarged. Spmetknes, but not so often, they take place over the ligd* ments of the knee. On account of their situation, and the swelling of the joint, they may be suspected to be scrofulous, though they are more sensible than stru- mous ulcers usually are. The sores just described are rendered less painful, their diseased disposition is checked, and the swelling of the joint diminished, by hem- lock Several irritable scrofulous ulcers are also particularly benefited by this me- dicine.” , . . * SirE. Home gives the preference to hem- lock poultices, unless their weight should be objectionable, in which case he. advises lint to be dipped in a decoction of the herb, and put on the s<»re. . . Of the ointment made with the inspissa- ted juice, Sir E. Home says but little in regard to its efficacy. 3. Ulcers curable by Sail- Water. Sir E. Home takes notice of other specific ulcers which yield to this application, alter resisting oilier remedies. Foultices, made ■with" sea-water, are often employed ; but this .gentleman seems to prefer keeping the part immersed in the wafer in a tepid state, about a quarter of. an hour, twice a day. When sea-water poultices bring out pim- ples in cases of scrofulous ulcers on the jeer/ and feet, Sir E. Home informs us that this disagreeable circumstance may be ob- viated by diluting such water with an; equal quantity of a decoction of poppies. After a time, the salt water may be tried by itself again. While each fresh poultice is prepa- ring, the part should also be immersed in such water wanned. When there is a tendency to anasarca, or when there is an unusual coldness in the limb, unattended with any propensity to mortification, tepid salt-water may be used with infinite advantage. wane uiv. v ' > " — - becomes larger and larger. Tne discharge consists of a thin, acrid fluid, which seems CUiisiais KJI 7. , to have a great share in making the disease spread. For all the three preceding diseases, a so- lution of the argentum nitratum is strongly recommended by Sir E. Home. Of this description are, a leprous eruption, mostly seen in men impressed in Ireland ; a disease of the skin induced by buboes, which have continued a great while after the venereal virus has been destroyed ; and the ringworm. All these diseases are most easily cured by applying to them a solution ot the argen- tum nitratum. The leprous eruption is communicated by contact, and makes its appearance in the form of a boil. This is converted into an ulcer, which discharges a fetid fluid, by which the surrounding skin is excoriated, and the ulceration is extended over a large surface. The pain is the most severe, and the discharge greatest, in hot weather. The parts first diseased heal, while others are becoming ulcerated, and the disease is always rendered worse by spirituous liquors, salt provisions, and catching cold. Sir E. Home remarks, that the disease in the skin, produced by the effects of very irri- table buboes, in constitutions broken down by mercury, is attended with ulceration of a more violent, deep, and painful kind, than the foregoing distemper. The progress of tli is disorder is, in other respects, very simi- lar to that of the leprous eruption. Although the ringworm only occurs in the form of an ulcer in warm climates, a mild species of the affection takes place in sum- mertime in this country. It seems to be infectious ; though it .often occurs without infection. It commences with an efflores- cence, which is attended with very trivial swelling, and spreads from a central point. The circumference of the efflorescence be- comes raised into a welt, while the rest assumes a scurfy appearance. The welt be- comes covered with a scab, which falls off', and leavef an ulcerated ring, in general, not more thah a quarter of an inch wide. The outer bargin of this ring continues to ulcerate, while the inner one heals, so that the circle 4. Ulcers curable by Ike Argentum Mtrajum . SirE Home notices, under this head, an 'ulcer which does not penetrate more deeply than the cutis, hut spreads in all directions, producing ulceration on the surface of the skin, and often extending nearly through its whole thickness. The part, first affected 5. Ulcers which yield to Arsenic. Thesores. which comeunderthe definition of noli me tangere or lupus, derive great benefit from this powerful remedy. SirE. Home observes, that they are nearly allied to cancer, differing from it in not contamina- ting' the neighbouring parts by absorption, and only spreading by immediate contact. From some cases, which tell under Sir E Home’s observation, he discovered, that ar- senic was not only efficacious as an external,, but also as an internal remedy. 1 shall not unnecessarily enlarge upon tins subject m the present place, as the reader may refer to the articles Arsenic , Cancer, Lupus, Hospital Gangrene. &c. for additional information rc ULCEUS. Native to the uses of this mineral in the prac- tice of surgery. Sir E. Home is an advocate for its employ- ment, both internally and externally, tor ulcers of untoward appearance on the legs. The fungated ulcer is particularly pointed out by this gentleman as being benefited by arsenic. This ulcer occurs on the calf of the leg, and on the sole of the foot. From its surface, a fungus shoots out, which is entire- ly different from common granulations, 'lhe neo -formed substance is radiated in its structure, the bottom of the ulcer being lhe central point, and the external surface, which is continually increasing, the circumference. The substance of this fungus is very tender, and readily bleeds. The first stage of the •disease sometimes has the appearance of a scrofulous affection of the metatarsal bones; but the parts seem more enlarged, and, when the skin ulcerates, a fungus shoots out. and betrays the nature of the case. One species of the fungated ulcer is capa- ble of contaminating the lymphatic glands ; the other is not so. The first is represented by Sir E. Home as being incurable by arsenic, or any other known medicine. The second yields to this remedy. Sir E. Home uses a saturated solution made by boiling white arsenic in water, for several hours, in a sand heat. He gives from three to ten drops internally ; and, for outward use, dilutes a dram with two pints of water, making it afterward gradually stronger and stronger, till it is of double strength. The application may either be made in the form of a poultice, or of lint dipped in the lotion. The best and safest preparation of ar- senic, both for internal and external use, is the kali arsenicatum The mode of em- ploying it may be learnt by turning to the articles Arsenic, Cancer, Potassa, Lupus, kc. 6. Ulcers attended with Varicose Veins. A certain kind of ulcer is very apt to oc- cur on the inside of the leg, and is equally difficult to cure, and liable to break out , again. It has the look of a mild, indolent sore; but, the branches and trunk of the vena saphena are enlarged, and this varix of the veins keeps the ulcer from healing. The sore is seldom deep, usually spreads along the surface, and has an oval shape, the ends of which are vertically situated. There is a pain affecting the limb rather deeply, extend- ing up in the course of the veins, and exas- perated by keeping the leg a long while in an i erect posture. This is a kind of ulcer, which derives immense benefit from a light roller, applied from the toes totbe knee, although the direct operation of the pressure of the bandage on the sore is itself productive of no particular good. Sir E. Home found, however, that many patients could not bear to w'ear laced stock- ings, or tight bandages, and that others received no relief from them. Hence, this gentleman was led to consider what else could be done for the cure of the varicose state of the veins. He represent?, that, in con- 02? sequence of the size of the vena saphena, and its numberless convolutions, the return of blood from the smaller branches is so im- peded, as to retard the circulation in the. smaller arteries, and to interfere with their action in forming healthy granulations. The coats, and valves of the veins also become thickened, so that the latter parts (the valves) do not do their office of supporting the weight ot the column of blood. These reflections induced Sir. E. Home to think, that some benefit might be obtained by taking off a part of the pressure of this column of blood, by making a ligature round the vena saphena, where this vessel passes over the knee joint. Thus the cavity of the vein at this part would be obliterated, and a kind of artificial valve formed. This gentleman recommended the follow- ing way of performing the operation : “ As the veins are only turgid in the erect posture, the operation should be performed while the paiient is standing ; and if placed upon a table, on which there is a chair, the back of the chair will serve him to rest upon; and he will have the knee-joint at a very con- venient height for the surgeon. The* leg to be operated upon must stand with the inner ankle facing the light, which will expose very advantageously the enlarged vena sa- phena passing over the knee-joint. While the patient is in this posture, if a fold of the skin, which is very loose at this part, is pinched up transversely, and kept in that position by the finger and thumb of the sur- geon, on one side, and of an assistant on the other, this fold may be divided by a pointed scalpel, pushed through with the back of the knife toward the limb to prevent the vein being wounded ; much in the same way as the skin is divided in making an issue. This will expose the vein sufficiently; but, there is commonly a thin membranous fascia con- fining it in its situalion ; and, when that is met with, the vein bad better be laterally disengaged by the point of the knife. This is most expeditiously done by laying hold of the fascia with a pair of dissecting forceps, and dividing it; for it is difficult to cut upon parts, which give little resistance, and there is a risk of wounding the vein. After this a silver crooked needle, with the pointrounded off, will readily force its way through the cellular membrane connected with the vein, without any danger of wounding the vessel, and carry a ligature round it. This part, or, 5 indeed, what may be considered as the whole of the operation, being finished, the patient had better be put to bed, so as to allow the vein to be in its easiest slate, be- fore the ligature is tied, and then a knot is to be made upon the vein: this gives some pain ; but it is by no means severe. The edges of the wound in the skin are now to be brought together by sticking-plaster, ex- cept where the ligature passes out, and a compress and bandage applied, so as to keep up a moderate degree of pressure on the veins, both above and below the part in- cluded in the ligature.” (Home on Ulcers o 2J)f>. Edit. 2.) lag LAG It appears that A. Parc proposed and per- formed an operation, similar to that des- cribed by Sir E. Home. (The Works of A. Parti translated by Johnson ; folio , p. 319.) An account of Mr. Brodie’s operation for the cure of varicose veins, and some additional remarks on the treatment of ulcers accom- panied with varices, will be found in a subsequent article. See Varicose Veins. A description of what has sometimes been called the hospital sore , is given under the head of Hospital Gangrene. For information on the subject of ulcers, consult Michael Underwood' s Treatise on Ulcers of the Legs, fyc. 8vo. Lond. 1783, and Surgical Tracts: 3d edit. 1799. B. Bell, A Treatise on the Theory and Management of Ulcers , fyc. New edit. 8 vo. 1791 ; and his System of Sur- gery. J. Meric , Be Curationibus Ulcerum diffcilium pretseriim in cruribus obviorvm. 4to. Goett. 1776. Baynton's Descriptive Ac- count of a new Method of Treating Old Ulcers of the Legs, 1799, ed. 2. 8 vo. Bristol, 1799. Whalely's Practical Observations on the Cure of Wounds and Ulcers on the Legs , without rest, St o. Lond. 1799. Practical Obs. on the Treatment of Ulcers on the Legs, to which are ad^ed, some Observations on Varicose Veins and Piles, by Sir Ererard Home, 1801, edit. 2. Principles of Surgery, by John Bell, Vol. 1. 1801. Hunter on the Blood, Inflammation, fyc. C. Curtis, An Account of the Diseases of In- dia, fyc. with Observations on Ulcers and the Hospital Sores of that country, fyc. 8 vo. Edinb. 1807. Brodie on the Treatment of Varicose Veins of the Legs, in Med. Chir. Trans. Vol. 7, P 195, j- Oliva? Olei. fluid un- cias tres. These are to be melted upon a slow fire, and then briskly stirred till cold. This ointment, spread on lint, serves as a simple dressing for wounds, ulcers, &c. UNGUENTUM CER7E CUM ACETO. — R- Cera; Alba? |iv. Olei Olivse fbj. Aceti Distillati ^ij. The vinegar is to be gradu- ally mixed with the two first ingredients, after these have been melted together. Dr. Cheston recommends this ointment for su- perficial excoriations, cutaneous eruptions, &c. UNGUENTUM CONTI— R. Foiiorum Conii recentium. Adipis Suiliae praeparatae, sing. ^iv. The hemlock is to be bruised in a marble mortar, after which the lard is to be added, and the two ingredients tho- roughly incorporated by beating. Tbey are then to be gently melted over the fire, and after being strained through a cloth, and the fibrous part of the hemlock well pressed, the ointment is to be stirred till quite cold. To cancerous Or scrofulous sores, th '13 oint- ment may be applied'with a prospect of ad vantage. ( Pharm . Chirurg.) The Pharmacopoeia of St. Bartholomew's Hospital directs the unguentum conii, vel cicutae, to be made as follows: — R. Foiio- rum Cicutae fbj. Adipis Suiliae ftjiss. Boil the leaves in the melted hog’s-Iarct until they become crisp. Then strain the ointrnent- A similar ointment might be more conve- niently made, by mixing the extraction conii with anv common salve. UNGUENTUM DIGITALIS.— R. Fo liorum Digitalis Purpureae recentium. Adi- pis Suiliae praparatie, sing. ^iv. This oint- ment may be made in the same manner as the unguentum conii, and tried in the same cases. UNGUENTUM ELEMI COMPOSITUM. — R. Elemifbj Terebinthinae ^x. Sevi Ovilli praeparati ft>ij. Olei Olivae ^ij. Melt the elemi with the suet ; remove them from the fire, and mix them immediately with the turpentine and oil. Then strain the mixture. — Sometimes employed for dressing ulcers, which stand in need of stimulating applications. UNGUENTUM GALL/E CAMPHORA- TUM. — R. Gall arum Pulveris Submission 3 *j • Camphorae 3ss. Adipis Suilla? prrnpii- ratae ^ij. Misce. — This is a very good ap- plication to piles, after their inflammatory state has been diminished by the liq.plumbi. acet. dibit, and leeches. UNGUENTUM HELLEBORl ALBL— R. Hellebore Albi pulv. gj. Adipis Suiliae praeparata? t-iv. Olei Limonis 3ss. Misce. This ointment will cure the itch, and several other cutaneous diseases. Tinea capitis will sometimes vield to it' UNO UNO 629 * UNGUENTUM HYDRARGYRI FOR- TIUS. — JJ,. Hydrargyri purificati Jfoij. Adi- pis Suilla 1 pracparafa? gxxiij. Sevi Ovilli pfaeparati !$j. First rub the quicksilver with the suet, and a little of the hog’s-lard, until the globules disappear ; then add the remain- der of the lard, and make an ointment. — This is the common slrong mercurial oint- ment. Of its uses we need say nothing in this place. UNGUENTUM HYDRARGYRI CAM- PHORATUM. — R. Unguent i Hydrargyri ^j- Camphorae 3 SS - Misce. — This is often recommended to be rubbed on thickened, indurated parts, with the view of exciting the action of the absorbents. Rubbed along the course of the urethra, it is very serviceable Jn diminishing and removing chordee. UNGUENTUM HYDRARGYRI MI- TIUS. — R. Unguenti Hvdrargyri fort. Rjj. Adipis Suilla? pra?parata? ffoij. Misce. — The weaker mercurial ointment is often rubbed on indurated, thickened parts and tumours, when the object is merely to promote their absorption; and it- is not adviseable to em- ploy the unguentum hydrargyri fort, lest a salivation should be induced. UNGUENTUM HYDRARGYRI N1TRA- TCS. — R. Hydrarg. Purificati Jj. Acidi Nitrosi Zij. Adipis praeparata? ^ v j . Ole; Oliva? ^iv. Dissolve the quicksilver in the nitrous acid ; and whilst the solution is yet hot, mix with it the oil and hog’s lard, pre- viously melted, but beginning to concrete, by being exposed to the air. This ointment is a celebrated application to the inside of the eyelids, in cases of chronic ophthalmy, and also to specks on the cornea? When blend- ed with a little olive oil, it also forms a very eligible stimulating dressing for numerous kinds of sores. It is particularly efficacious in curing tinea capitis, and many other cuta- neous diseases. UNGUENTUlM HYDRARGYRI NITKI- CO-OXYDI. — R. Hydrargyri nitrico-oxydi -p. Cera? Albas ^ij. Adipis prrnpar. ^vj. Misce. — This is a common stimulating ap- plication to indolent ulcers, and sores in ge- neral. UNGUENTUM HYDRARGYRI PRiC- CI PIT ATI ALBI — R. Hvdrarg. Prcemp. Albi 3j- Adipis prajparatae ?iss. Misce. — An useful application in certain cases of por- rigo, and some other cutaneous diseases. See Porrigo. UNGUENTUM LIQ. PLUMBI ACETA- TIS. — R. Liquoris Plumbi Acetatis ^v. Adipis Suilla? fbj- Cerae Aibae Z\v. Melt the ingredients together, and continue to stir them till cold. — This ointment is em- ployed with great advantage as a simple *The preparation of this article will be greatly expe- dited by rubbing the mercury in the first instance, with a small proportion of the article familiar to us by the appellation of goose-grease; this can be done in a glass mortar, or even upon a marble slab, by a spatula; it has such immediate effect upon the mercury. One ounce of this article will be sufficient, with trituratiw for the space of one minute, to make the globules of the quirk- silver entirely disappear, and render it at once fit for admixture with the proper proportion of lard. — Am. Ed, Vnj, . jr ft? dressing. According to Mr. Dunn, of Scar- borough, it is much improved by pouring the liquified mixture, before the lead has been added to it, into cold water. It is then to be rubbed in a mortar, or on a slab with the liq. plumbi acet. The water occasions a fine white cloudy precipitation, which gives to the composition abetter ap- pearanc* 1 . UNGUENTUM OPHTH ALMICUM.— ft. Adipis Suilla? praeparatae |s«. Tutiae praepa rata?, Bol Armen, sing. 3'j- Praecip. Hy- drarg. Albi 3j. Misce. — Janin’s celebrated ophthalmic ointment, frequently mentioned in the parts of this work, which relate to dis- eases of the eye and eyelids. UNGUENTUM OXYGENATUM, vel ACIDI NITROSI. — R. Axungia? Suillae re cenlis; non salsa? uneias sedecim. Leni calore in vase vilreo lente liquefactis ant con- tiuua a-itatione instillentur, Acidi Nitrici unciae dua?. Massa igni exponatur, donee ebullire coepit ; tunc ab igne removeatur, fri- gefactaque servelur. In this process the nitric acid is decom- posed, the nitrous gas escaping, and the oxy- gen combining with the lard. This oint- ment was particularly recommended by Aly- on,as an application to venereal and herpe- tic ulcers. Its virtues are said to vary consi- derably, according to the strength of the acid employed, and it is not generally deemed so efficacious as the ointment of nitrate of mer- cury. UNGUENTUM PICIS.— ft. Picis, Sevi Ovilli prmparati, sing. ftss. Melt, and then strain them. UNGUENTUM PICIS COMPOSITUM, — R- Unguenti Picis, Unguenti Plumbi Superacetatis sing. Rjss. Misce. The two preceding ointments are applica- ble to cases of tinea capitis, and some erup- tive complaints. Also to some kinds of irri- table ulcers. UNGUENTUM PICIS CUM SULPHU- RE.— R. Unguenti Picis, Unguenti Sul- pburis, sing, ^iv, Misce. — This is one of the most common, and, I believe, the most effi- cacious applications for curing tinea capitis, or porrigo. UNGUENTUM PLUMBI SUPERACE- TATIS. — R. Plumbi Superacetatis 3»j* Cera? Alba? Zij. Olei fbss. The superacetate of lend, previously powdered, is to be triturated with part of the olive oil. Th# melted wax and rest of the. oil are then to be added. This is a good dressing for cases requiring a mild astringent application. UNGUENTUM RESINiE.— R. Resina? Flavee, Cerae Flavae sing. ft>j. Olei Oliva? Jbj Melt the resin and wax with a slow fire ; then add the oil, and strain the mixture while hot. — This is a common application to ul- cers, which stand in need of being gently sti- mulated. UNGUENTUM SAMBUCI, — ft. Florum Sambuci, Adipis Suillae, singulorum ft>j. The hag’s lard being melted, boil the elder flowers in it till they become crisp, then strain the mixture. UNGUENTUM SULPHURIS— R, URETHRA u&j pis Suilla? lt>ss. Florutn bulphuris ?iv. Misce. UNGUENTUM TUTIjE.— ft. Tutiac pnc- parata?, Unguenti Celacei q. s. Misce.--- Used for smearing the borders and inside of the eyelids, in cases of chronic ophtbalmy, &c. UNGUENUJM TUTliE COMPOS1TUM. — 15;. Tuliae prseparatae, Lapidis Cularriinaris pra;parati, sing. 3vj. Camphorae 334 The disease has generally made consider- able progress, before surgical assistance is required, and the stricture may be so ad- vanced, that a small bougie cannot be made to pass, without a great deal of trouble. If the end of a small bougie, let it be ever so small, can be introduced through the stric- ture, ih»t cure is then in our power. How- ever, a small bougie frequently cannot pass in the first instance, and even not after re- peated trials. Often when the stricture is very consider- able, a great deal of trouble is given by occasional spasms, which either resist the introduction of a bougie altogether, or only allow a very small one to pass. At other periods, however, a larger one may be in- troduced. In these circumstances Mr. Hunter mentions, that he was sometimes able to make the point of the bougie enter, by rubbing the outside of the perihasum with the finger of one hand, while he push- ed the bougie on with the other. The same eminent practitioner often succeeded by. letting the bougie remain a little while close to the stricture, and then pushing it on. Sometimes the spasm may also be taken off •by dipping the gians penis in cold water. Although in cases of permanent stric- tures, the bougie may not pass at first, yet after repeated trials, it will every now and then find its way. In this manner future attempts become more certain and easy. However, the success of the subsequent trials to introduce a bougie does not always depend on the instrument having been once or twice passed. Sometimes it can be in produced to-day, but not to-morrow ; and in this state, the case may continue for weeks, notwithstanding every trial which can be made. Mr. Hunter observes how- ever, that in general, the introduction of the bougie becomes gradually less difficult, and therefore, that we ought not to despair of success in any case. When the passage is very small, it is not easy to know whether the bougie has enter- ed the stricture or not ; for bougies as slen- der as those which must be at first employ- ed, bend so very easily, that the surgeon is apt to fancy, that they are passing along the urethra, while they are only bending. Mr. Hunter advises the surgeon first to make himself acquainted with the situation of the stricture, by means of a common-sized bougie ; and then to take a smaller one, and when its point arrives at the stricture, the instrument is to be gently pushed for- ward, but only for a short time. If the bougie has passed further into the penis, the surgeon may know how far it has entered the stricture, by taking the pressure off (he bougie. For, if it recoil , he maybe sure that it has not passed ; at least, has not pass- ed far, but only bent. On the contrary, if it remain fixed , and do not recoil, it has cer- tainly entered the stricture. However, the preceding remarks are said not to be so applicable when a very small bougie is employed, which may become bent, without our being aware of the cir- cumstance,. A bougie may frequently be introduced a very little way, for instance, only one-tenth of an inch, and then it bends, and cannot be pushed further. To determine whether this is the case, Mr. Hunter says, it is necessary to withdraw the bougie and examine its \ end. If the end be blunted, we may be sure, that the bougie has not entered at all ; but if it be flattened, for an eighth, or tenth of an inch, be grooved, or have its outer waxen coat pushed up to that extent; or it there be a circular impression made upon the bougie,* or only a dent on one side, made by the stricture ; we may be sure that the instrument has passed ns far as these appearances extend. It then becomes ne- cessary to introduce another of exactly r the ' same size, and in the same manner, and to let it remain as long as the patient can bear it, or convenience will allow. By repeti tions of (his plan, the stricture will be over- come. Mr. Hunter remarks, that the time which each bougie ought to remain in the passage must be determined by the feelings of the patient ; for if possible, no pain should ever be given. If the patient should experience very acute pain when the bougie is passing, it ought not to be left in the urethra above five; or at most, ten minutes ; pr not so long if the pain be exceedingly severe. Each time of application should afterward be lengthened so gradually as to be impercep- tible to the feelings of the patieql, and the irritability of the parts. Mr. Hunter affirms, that he has known many patients, who could not bear a bougie to remain In the passage ten, or even five minutes, till after several days, and even weeks, but who in time were able to wear the instrument for hours, and this, at last without any diffi- culty. The best time for keeping a bougie in the urethra, is when the patient has least to do; or in the morning, while he is in bed, if he can introduce the instrument him- self. Mr. Hunter next observes, that the bougie should be increased in size, according to the facility with which the stricture becomes di- lated, and the case with which the patient bears the dilatation. If the parts are very firm, or very irritable, the increase of the size of the bougie should be very slow, so as to allow them to become gradually adapted to the augmented size of the instrument. But if the sensibility of the parts will allow, the increase of the size of the bougie may be somewhat quicker, but never more siuR den than the patient can easily bear. The surgeon must continue to increase the size of the bougie, till one of the largest size can freely pass ; nor should the use of this be dis- continued till after three weeks, ora month, in order that the dilated part may have time to become habituated to its new position, and lose its disposition to contract again. However, Mr. Hunter believed, that the permanency of a cure, effected on the pvin URETHRA • ipie ol mlataiiou, could seldom be depend- ed upon. At the present day, many surgeons prefer bougies composed of metal, flexible enough to allow their curvature to be adapted to the bend of the urethra, yet sufficiently firm to retain the figure given them, while they are employed. Others very commonly use iron sounds, which, in cases where it is necessa- ry to have an instrument possessing more firmness than a wax bougie, and having a point more unchangeably turned upwards than that of the latter instrument, may have advantages. But, for all ordinary cases, 1 consider a common bougie a safer and bet ter instrument ; one with which the surgeon is less apt to exert unwarrantable force, so as to occasion a dangerous degree of irri- tation, or, what is worse, a false passage CURE OF STRICTURES BY ULCERATION. This is also accomplished by means of a wax or metallic bougie, and the plan may be tried both when the instrument can, or cannot be introduced through the stricture. In the first instance, the method is less pro- per, because the stricture admits of being dilated. In order to cure a stricture by making it ulcerate, the bougie is to be introduced as far through the contracted part as possible, and the size of the instrument is to be aug- mented, as fast as the sensations of the pa- tient can well bear. In this manner ulcera- tion will be produced in the part which is pressed; and Mr. Hunter remarks, that the cure will be more lasting, because more of the stricture is destroyed than when the parts are simply dilated. This eminent surgeon notices, however, that few patients w ill sub- mit to this practice, and that few indeed would be able to bear it, since it is apt to bring on violent spasms in the part, attend- ed with a very troublesome retention of urine If the smallest bougie cannot be made to pass a stricture, by using some degree ot torce, dilatation becomes impracticable ; and as the stricture must be destroyed, something else must be tried. In many cases, says Mr. Hunter, it may be proper to get rid ot the stricture, by making it ulce- rate, or, in other w'ords, be absorbed. Bou- gies,-intended to excite ulceration, need not be so small as in the foregoing cases, as they are not designed to be-passed through the stricture ; and, in consequence of being of the common size, they may be more surely applied to the parts causing the obstruction. The force applied to a bougie, in this case, should not be great : for a stricture is the hardest part of the urethra ; and it a bougie forcibly pushed on, its end may slip off the stricture, before ulceration has com- menced, and make a false passage for itself in the corpus spongiosum urethrae. In trying to cure strictures by ulceration.' the utmost attention must be paid ; and if the patient does not make wmter better, not- withstanding the bougie passes further, the surgeon may be sure be Is forcing a false passage. When the stricture has so far yielded, as to allow a small bougie to be introduced, the treatment is then to be conducted on the principle of dilatation. Mr. Hunter observes, that whenever a bougie ot a tolerable size passes with ease, and the parts and the patient have become accustomed to it, the surgeon need no longer attend for the purpose of introducing it, 1 he patient may now be allowed to intro- duce bougies himself; and when he can do tins with ease, the business may be trusted to him,, as he can make use of the instru- ments at the most convenient times, so that they may be more frequently and longer applied. In the mean while, the surgeon should only pay occasional visits. Mr. Hun- ter adds, that this practice of the patient, under the surgeon’s eye, by which means the former learns the art of introducing bo; - gies, is the more necessary, since strictures are diseases which commonly recur ; and, therefore, no man w ho has ever had a stric ture, and is cured of it, should rely on the cure as lasting ; but should always be pre- pared for a return, and always have some bougies by him. He should not go a jour- ney, even of a week, without them ; and the number should be according to the time which he is absent, and the place to which he is going , for in many parts of the world he cannot be supplied with them. To prevent the inconvenience of a bougie, slipping out, or the mischief of its gliding intd the urethra, a soft cotton thread must be tied round that end of the bougie which is out of the urethra, and then round the root of the glans. This last part of the thread should be verv loose. The projecting portion of the bougie should also be bent down upon the penis, by which means it is rendered less troublesome, and more secure, (See Hunter on the Venereal Disease. When a considerable part of the bougie remain, out of the urethra, surgeons usually clip a piece d{ it off. In many examples, .in which a stricture i accompanied with excessive irritability in the urethra, much pain, and a tendency to frequent retentions of urine, when a com - mon bougie is employed, it becomes advisea ble to alter the plan of treatment, and use either flexible metallic, or elastic gum bon gies. (See Bougie.) Desault commonly cured all strictures by the skilful employment of flexible gum catheters, which his patients were directed to wear a certain length of time every day. These last instruments produce less pain and irritation than any kind of bougie, more especially when thc ( wires are withdrawn ; and were I to be my self altiicted with strictures, I should feel strongly disposed to attempt their removal by the use of elastic gum catheters, which are unquestionably the mildest and least painful means of cure. I have seen cases, however, in which the flexible metallic bou- gie seemed to cause much less irritation than any other kind of bougie: but in general. URETHRA fi3ti those made ot elastic gum give the least pain. Metallic bougies possess the advan- tage of retaining the exact curvature of the passage better than others ; and, as I have observed, they enable the surgeon to employ more force, and this with more precision than can be done with a wax bougie. Yet, as force is not a principle to be much com- mended in the treatment of ordinary stric- tures, I Uoubt whether such instruments will long retain as many employers as they have now acquired, and many of whom use them indiscriminately in all cases. Small catgut bougies are chiefly eligible, when the cure by dilatation is preferred, and the smallest bougies of other descriptions cannot be in- troduced through the stricture. CORE OP STRICTURES WITH THE ARGENTUM N1TRATUM. Wiseman makes mention of the plan of curing strictures in the urethra by means of caustic. He observes, that when the ob- struction is a caruncle, and you cannot pass it, you may well conclude it is callous : •‘in which case, you may pass a cannula into the urethra to that caruncle, and, whilst you hold it there steady, you may convey a grain of caustic into the cannula, and press the caustic to it ; and whilst you hold it there, you will perceive its operation, by the pressing forward of the cannula.” About the year 1752, Mr. Hunter attended a chimney-sweeper, who had a stricture. JNot finding that any benefit was derived from the use of common bougies, for a space of six months, Mr. Hunter, unaware of the above passage in Wiseman, conceived, that the stricture might be destroyed by escharo- tics, and the first attempt, which he made, was with red precipitate. He put some salve on the end of a bougie, and then dip- ped it in red precipitate. The bougie in this state, was passed down to the stricture ; but Mr Hunter found, that it brought on con- siderable inflammation all along the inside of the passage, as he thought, in conse- quence of the precipitate being rubbed off, while the bougie was passing to the stricture. He then introduced a silver cannula down to the stricture, and again passed the bougie with precipitate through the tube. As the patient, however, did not make water any better, and the smallest bougie could not be introduced through the stricture, it was suspected, that the precipitate had sufficient power to destroy the obstruction. Mr. Hunter was induced, therefore, to fasten a small piece of the argentum nitratum on the end of a piece of wire with sealing-wax, and introduce the caustic through the can- nula to the stricture. After having made the application ) three times, at intervals of two days, he found that the man voided his urine much more freely, and on applying the caustic a fourth time, the cannula went through the stricture. A bougie was intro- duced for a little while afterward, till the man bad completely recovered. Having experienced this success, Mr. Hun- ter was encouraged to apply his mind to the invention of some instrument, better suited to the purpose, than the above contrivance ; and an improved instrument was devised, although he acknowledges, that it was not perfectly adapted to strictures in every situ- ation in the urethra. He remarks that the caustic should be prevented from hurting the unaffected part of the urethra by introducing the active substance, through a cannula, down to the stricture ; and that it should be capable of protruding a little beyond the end of the cannula, by which means it will only act upon the stricture. The caustic should be fixed in a small portcrayon, and it is ne- cessary to have a piece of silver of the length of the cannula, with a ring at one end, and a button at the other, of the same diameter as the cannula. The button forms a kind of plug, which should project beyond the end of the cannula in the urethra, so as to make a rounded end ; or, Mr. Hunter says, the portcrayon may be formed with this button at its other end. The cannula, with the button, is to be passed into the urethra, and when it reaches the stricture, the silver plug should be withdrawn, and the portcrayon with the caustic introduced in its place ; or, if the plug and portcrayon are on the same instrn- ment, then it is only necessary to withdraw the plug, and introduce the portcrayon with the caustic. The plug, besides giving a smooth rounded end to the cannula, answers ano- ther good purpose, by preventing the tube from being filled with the mucus of the ure- thra, when the instrument is passing in- ward, which mucus would be collected iu the end of the cannula, dissolve the caustic too soon, and hinder its application to the stricture. When the stricture was beyond the straight pari of the urethra, Mr. Hunter owned, that it was difficult to apply caustic to the disease through a cannula. A better mode of applying lunar caustic lo strictures was afterward devised by Hunter, and has since been extensively introduced into practice by Sir E. Home. This gentle- man directs us to take a bougie of a size that can be readily passed down to the stric- ture, and to insert a small piece of lunar caustic into the end of it, letting the caustic be even with the surface, but surrounded every where laterally by the substance of the bougie. This should be done some little time before it is required to bo used; for the materials of which the bou- gie is composed, become warm and soft by being handled in inserting the caustic; and. therefore, the hold which the bougie has of the caustic, is rendered more secure after the wax has been allowed to cool and hard- en. The bougie thus prepared, is to be oiled and made ready for use ; but before passing it, a common bougie of the same size is to Or- introduced down to the stricture, in or- der to clear the canal, and to measure the exact distance of tho stricture from the ori- fice of the urethra. This distance being marked upon the armed bougie, it is to be passed down to the stricture, a? soon ns (hr URETHRA. 037 other is withdrawn. The caustic, in its pas- divided parts a flexible’ gum-cat lietcr into sage, is scarcely allowed to come into con- the bladder. This I have done myself, and fact with -any part of the membrane, because have frequently seen it performed by Mr. the point of the bougie, of which the argen- Hunter, and it always succeeded ; neither turn nitratum forms the central part, always bringing on so much inflammation as was moves in the middle line of the canal ; and, expected, nor being attended with any indeed, the quickness with which it is con- symptoms of irritation, vcyed to the stricture, prevents any injury “ This practice has by othersurgeons been of the membrane lining the passage when carried still further ; the portion of diseased the caustic accidentally touches it. urethra has been dissected out, and entirely In this mode the caustic is passed down removed ; nor has so severe an operation with little or no irrilation to (he lining of always brought chi untoward symptoms; the urethra ; it is applied in the most advan- and patients have recovered, tageems manner to the stricture, and can be “ If the membrane of the urethra, when retained in that situation sufficiently long to produce the desired effect. The reasons urged in favour of the em- ployment of bougies armed with the lunar caustic, arc, that a permanent cure is effect- ed, which common bougies cannot accom- plish ; that the pain arising from the applica- tion of the argentum nitratum to the stric- ture, is very inconsiderable ; and that nei- ther irritation nor inflammation is found to ensue. The meaning of these remarks, however, is to be received as a general one, liable to exceptions. Indeed, SirE. Home himself has candidly acknowledged, that some inconveniences occasionally follow the . use of armed bougies. But w bat practice, however judicious and eligible, is altogether free from occasional ill consequences? Sir E. Home remarks, that against treating stric- tures of the urethra with caustic bougies, numerous objections have been adduced, and many bad consequences have been at- tributed to the practice, without any real foundation ; “for whatever, <1 priori, might be supposed the effects of so violent an ap- {^icr.tion, to a membrane so sensible and ir- ritable as the urethra, and I will admiit tiiat it is very natural to conceive they would be very severe, (lie result of experience, the only thing to be relied on, evinces the contrary. The pain that is brought on, is by no means violent ; and neither irrita- tion nor inflammation is found to take place. “ That cases do occur, in which strictures have produced so much mischief, and ren- dered so great an extent of the canal dis- eased, that the use of the caustic has proved unsuccessful, is certainly true; and several of these cases have fallen within my own know- ledge. But when it is stated that none, even of these, were made worse by its use; that no bad consequences attend it ; and that no other mode, at present known, is equally efficacious ; «»y occasional want of success cannot be considered as an objec- tion to this mode of practice. “ But if the apprehension of violent effects from the caustic, however ill-found- ed, cannot be removed, let the alternative be considered ; namely, the only operation previously in use, where a stricture cannot be dilated by the bougie. . “ In those cases we are obliged to have recourse to means certainly more severe and violent, laying open with a knife the diseased urethra, and passing through the Yol. H diseased, is capable of suffering so much injury without any consequent symptoms of irritation, it cannot be doubted that it will bear with impunity to be touched, in a very partial manner, several different times with lunar caustic.” Sir Everard afterward proceeds: “Having met with a number of facts, from which a general principle appears to be established, that the irritable state of a stricture is kept up, and even increased, by the use of the bougie, but lessened and entirely destroyed by the application of lunar caustic ; I am desirous to communicate my observations upon these facts, and to recommend the use of the caustic in many cases of irritable stricture, in preference to the bougie. “ As the use of the caustic upon this prin- ciple is, I believe, entirely new, and is con- trary to every notion that has been formed upon the subject, it will require something more than general assertion to gain even the attention of many of my readers, snil more their belief; 1 shall therefore detail the circumstances as 'they occurred, by which I conceive the propriety of this prac- tice to be established : and afterward make some observations upon the principle on which it depends. “ My connexion in practice with Mr Hunter afforded me opportunities of attend- ing to cases of stricture in all their different stages; many of them brought on duringa long residence in India, attended with great irritability, and exceedingly difficult of cure. “ One case of this kind admitted the pass- ing of a small bodgie ; but, in the course of three years, very little was gained hv a steady perseverance in the use of that in- strument, either in dilating the canal, or palliating the symptoms of stricture ; this made me look upon the bougie as less effi- cacious than I had always been taught to believe it. I was willing, however, to con- sider this as an uncommon case, depending more on the peculiarities of the patient’s constitution than on the nature of the dis- ease: but I found, on a particular inquiry, that several other gentlemen from Jntha were under circumstances nearly similar; the bougie only preventing the increase of the stricture, but being unable to dilate it beyond a certain size ; and when it was left off, the stricture in less than two months returned to its former state of contrac- tion. • tJKETHRA. l{ What plau ought to be followed in such cases, I was then unable to determine ; but, that the bougie could not be depended on was evident: During the suspense, the fol- lowing case came under my care. “In August, 1794, a gentleman consulted me for some symptoms which had been considered as indicating the presence of gonorrhoea; but, as they did not yield to the common treatment in the usual time, he was induced to take my advice res- pecting the nature of his complaint In the necessary inquiry, to obtain a perfect his- tory of the case, among other things it was stated, that, nineteen years before, there was a stricture which became very trouble- some, and that Mr. Hunter, by the desire of the patient, had applied the caustic, by which the stricture was removed, and never afterward returned. He said that he was one of the first persons on whom the caus tic had been used. From this account, I was naturally led to believe that the stric- ture had gradually returned, and was now increased, so much as to produce the pre- sent symptoms ; a discharge being almost always a symptom of stricture when it is much contracted ; but, upon exaininingthe canal, a bougie of full size passed on to the bladder without the smallest impediment. I therefore took up the case as an inflamma- tion in the urethra ; and large doses of the balsam of copaiva, given internally, effected a cure. 11 The circumstance of a stricture having been removed nineteen years before, and not returning, made a strong impression on my mind, and made, me desirous to ascer- tain whether this practice could be employ- ed in cases of stricture in general, and the cure produced by it equally permanent. A short time afterward, I had an opportunity of trying it in the following case. “ A captain in the East India Company’s service, in September, 1794, applied to me for assistance. His complaints were, great irritation in the urethra and bladder, con- stant desire to make water, and an inability to void it, except in very small quantities. These symptoms had been at first supposed to arise from gonorrhoea, afterward render- ed more severe by catching cold ; but, not yielding to the usual remedies for gonor- rhoea, they were investigated more minute- ly, and a stricture was discovered in the urethra. The mode of treatment was now changed, and the bougie employed ; but its use aggravated all the symptoms, and brought on so great a degree of irritability in the bladder and urethra, that there was nn alarm for the patient’s life, which was the reason for applying for my assistance. il Besides thejocal symptoms, this patient had those of quick pulse, white tongue, hot and dry skin, loss of appetite, and total want of sleep, with frequent attacks of spasm on the bladder and urethra. A very small flexible gum-catheter was passed, and the water drawn off, in quantity about a pint, which gave him great Fefief : this was re- pe ged morniug and evening, to keep the bladder in as easy a state as possible ; but, in other respects, he continued much the same. “ As the present symptoms were brought on by the use of the bougie, little good was to be expected from that instrument; and where the urethra- had been so easily irrita- ted, and was disposed to continue in that state, there was no prospect of the use of the bougie afterward effecting a cure. These circumstances I explained to the patient; and mentioned, in proof of my opinion, the case in which so little had been effected in three years. “ I then proposed to him a trial of the caustic, with a view to deaden the edge of the stricture, as the only probable means of effecting a cure. The degree of irritation was already great ; I was, however, led to believe that the application of the caustic was not likely to increase it ; since, by destroying the irritable part, it might lessen and even remove the spasmodic affection ; but if, contrary to my expectation, the irritation continued, we still should be able to draw off' the water, as the slough formed by the caustic would prevent the edge of the stricture from acting and obstructing the instrument. “ The application of the caustic was, upon these grounds, determined on ; and it was applied in the following manner. “ I passed a common bougie, nearly the size of the canal, down to the stricture, to ascertain its exact situation, and to make the canal of the urethra as open as possible The distance was then marked upon a bougie armed with caustic, of the same size, which was conveyed down as quickjpr as the nature of the operation would admit. It was retained upon the stricture with a slight degree of pressure ; at first there was no pain from the caustic, but a soreness from pressure ; in less than a minute a change was felt in the sensation of the part, it was at first a heat, succeeded by the burning pain peculiar to caustic ; as soon as this was distinctly felt, the bougie and caustic were withdrawn, having remained in the urethra about a minute altogether. The soreness, he said, was entirely local, by no means severe, was unaccompanied by irritation along the canal, and he thought the uneasiness in the bladder diminished by it. He described the pain as resembling very exactly the first symptoms of gonor- rhoea. This sensation lasted half an hour after withdrawing the bougie. “ The caustic was applied about one o’clock in the forenoon, and he passed the day more free from irritation than he had since the beginning of the attack, which had lasted six days. In the evgning, the water was drawn off with more ease than the night before. He passed a tolerable night, and, the next day, continued free from irritation. On the third day, the caus- tic was again applied in the forenoon ; the painful sensation was less than on the for- mer application, lasted a shorter time, and in an hour after the armed bongio was with- btfETHKA. Orawn, he made water freely tor the first time since the commencement of his indis- position. He said the irritation in the blad- der was removed, and lie felt very well, his appetite returned, he slept very well, and continued to void his urine with ease. “ In this state, nothing was done till the fifth day, leaving always a day between the applications of the caustic. * “ Qn this day a common-sized bougie went readily into the bladder; it was im- mediately withdrawn, and the cure was considered as complete ; no bougie was afterward passed, lest it might bring back an irritation upon the passage. I met this gentleman twelve months afterward, and he assured me he had continued perfectly well, and 1 have since learned that, in three years, there has been no return. “ From the result of this case, I was en- couraged to hope that the caustic might be applied to strictures in the urethra with more confidence than I had hitherto be- lieved, since it evidently did not bring on or increase the general irritation, but,- on the contrary, seemed to allay it.” The foregoing case, together with ano- ther which Sir E. Home has related, con- vinced this gentleman that he had disco- vered an effectual mode of treating such strictures as do not admit of being relieved by the common bougie. Hence he adopted the use of armed bougies as a general prac- tice ; but he has not concealed the circum- stances under which the method does not prove successful. Sir Everard informs us, that “ in some constitutions, where the pa- tients have resided long in warm climates, every time the caustic is applied to a stric- ture, a regular paroxysm of fever, called by the patient an ague, takes place ; and this has been so violent as to render it impossi- ble to pursue this mode of practice. Of this I have met with two instances. I consider this disposition to fever as the effect of cli- mate, and not of any natural peculiarity of constitution; for the brother of one of these patients laboured under the same disease, but as he had not been in warm climates, It was removed by the caustic without his ex- periencing such attacks.” In gouty constitution?, attacks of the gout have in two instances brought on spasmo- dic constrictions, after the stricture had been removed by caustic. This, however, cannot be called a failure of the caustic. It only shows that gout can affect strictures, and reproduce them. “In some patients the strictures are so obdurate, that the use of the caustic is ne- cessary to be continued for a longer time, than the parts can bear its application, or even that of the bougie passing along the urethra; irritation therefore comes on, and stops the progress of the cure, and when the same means are resorted to again, the same thing takes place. The cases of failure ot this kind that I have met with, some of which may yet ultimately be cured, if the patients will take the necessary steps for that purpose, amount in all to six 539 “ In some patients the stricture is readily removed by the caustic, but, in a few weeks contracts again. The stricture being wholly spasmodic, the caustic, by taking off the spasm, is allowed to pass through, and can- not completely destroy the stricture. Of this kind I have met with one instance which I must consider as a failure, as I have hitherto been unable to get the better of it. “ In those cases where the caustic gradu- ally removes the stricture, and brings the urethra to a size that allows the patient to make water perfectly well, if there is any return, it is not to be attributed to the fail- ure of the caustic, but to the want of proper management, either from the caustic being too small, or its use left off too soon ; but all such cases are, I believe, within the pow- er of being cured by the caustic, if its use is recurred to when that is found ne- cessary.” For the generality of strictures in the urethra, which do not occupy more extent of the canal than if caused by a piece of packthread being tied round it, bougies, armed with lunar caustic, answer very well, and so, I believe, do common bougies, to which the general preference ought per- haps to be given. For cases, also, in which the urethra is diminished in diameter, for aa inch or more, common bougies must be most advantageous, that is to say, when they can be introduced through the stric- t re, so as to cure it on the principle of dilatation. Whether, in ‘certain cases, where no pro- gress can be made with common bougies, it is better to try caustic, or attempt to force the obstruction with a sound, is a question on which there is a great deal of difference of opinion. “ The practice of pressing firm bougies, or metallic instruments, so as to force the stricture, or to produce an ulcera- tion of it, (says a modern writer,) so fre- quently has been found to form false pass- ages, fistula?, and gangrene, that I need here make no further observation on the practice, or its consequences. All the advantages that can be gained by pressure, tearing through the stricture, or producing ulceration of it, may be obtained by a careful and judicious use of the caustic, which will be found on the whole a safer application, and will be at- tended with less inflammation and pain.” ( Wilson on the Male Urinary and Genital Or- gans, p. 383.) This gentleman is not, how- ever, an advocate for the caustic in every case. “ I consider it,” says he, “ the safest practice in cases which will not yield to the introduction of bougies, and which require a portion of the stricture to be destroyed ; but the symptoms which sometimes attend its use, and the injury which may be done by its improper application, should confine it to those cases.” ( p . 385.) I shall conclude this part of the subject of strictures, with inserting some of the general directions given by Sir £. Homeisovv to arm the bougie, and apply the lunar caustic to- strictures. 540 URETHRA. In arming a bougie, it will be difficult to get a piece of caustic of a proper shape and aize for (he purpose, unless it be cast in a small cylindrical mould. “ If these pieces are thicker than the bougie can readily en- close, by putting them in water the outside quickly dissolves, so as to diminish their size as much as is required. The piece of caus- tic, so prepared, is to be cut into small por- tions, about a quarter of an inch in length, and an orifice being made in the end of a bougie, the caustic is to be inserted into it, and the bougie rolled so as to be made per- fectly smooth, taking care that the sides of the caustic are every where covered, and only the end exposed. “ This was the mode (says Sir Everard) in which I armed bougies, when I first took up this practice ; but it happened, that, in two or three instances, the caustic was left in the urethra ; that canal, when in a very irritable state, grasped the bougie, and pulled the caustic out ; I was therefore led to consider how such an accident might he prevented, and applied to the makers of bougies for that purpose. Mr. Pass, the late beadle of the Surgeon’s Company, who dealt in bougies, discovered a very ingenious and effectual mode of securing the caustic. In forming the bougie, a piece of wire, the size of the caustic, is rolled up along with it, passing into the substance for half an inch ; when the bougie is nearly finished, the wire i3 withdrawn, and the caustic inserted in iis place after this, the bougie is rolled again, so that the sides of the caustic become firmly cemented to the linen, by means of the com- position of the bougie, and when cold, can- not be separated by any force. In this way bougies are now generally armed. “ After the bougie has been thus prepared, the distance of the stricture from the exter- nal orifice is to be measured, and the canal cleared by passing a coramoft bougie fully as large as that which is armed. The armed bougie, wiib the distance marked upon it, is then to be introduced, and applied to the stricture; when it is brought in contact with the obstruction, it is to be steadily retained there, with a moderate degree of pressure at first, and less as it is longer continued, since the bougie becomes soft by remaining in the urethra, and readily bends if the pressure is too great. The time it is to remain depends a good deal upon the sensations of the pa- tient, and the length of time the parts have been diseased ; but on the first trial it should be less than a minute, as it then commonly gives greater pain than on any subsequent application. The pain produced by the caustic Js not felt so immediately as it would be natural to expect; the first sensation arises from the pressure of the bougie on the stric- ture ; a little afterward, there is the feeling of heat in the parts ; and lastly, that of pain. “ As soon as the caustic begins to act, the surgeon who makes the application is made sensible of it by the smaller arteries of the parts beating with unusual violence, which is very distinctly felt by the finger and thumb dial grasp (be penis 4 The pain that is brought on by the caus- tic lasts for some time after it is withdrawn J but this period differs in almost every patient, being sometimes extended to half an hour, and sometimes only a few miuutes. “ The kind of pain is heat and soreness, which is not severe, not being accompanied with the peculiar irritation, upon so many oc casions experienced by patients who have strictures ; an irritation that cannot tfe de- scribed, which is most insupportable, and is too often brought on by dilating strictures with the bougie.” In the vol from which the above directions are taken, Sir Everard Home recommends the patient to make wa- ter, as soon as the armed bougie is with- drawn ; but in a subsequent vol. he explains bis change of opinion upon this point : “ I not only have no wish that the patient should make water immediately after the applica- tion, but would rather that it be retained some time.” (On Strictures, vol. 3, p. 51 8i;o. Lond. 1821.) “ It happens not unfrequently,” says Sir Everard Home, “ that at the first time of making water, some blood passes along with it. This is rather favourable ; as, when the parts bleed, the stricture usually proves to be so far destroyed, that at the next trial the bougie passes through it. Every other day appears, in general, to be as often as it is prudent to apply the caustic. I have, how'-, ever, done it every day in very obstinate cases, where ihe parts are less sensible, with- out any detriment.” In his third volume, lately published, he states, that he now rarely passes the bougie oftener than every third day, and never when the pain from the last application has not entirely gone off. He also never con- tinues any one application beyond the time when the pain begins to extend further than the spot to which the armed bougie is ap- plied. (Vol. 3, p. 51.) The bougie which is passed down to pre pare the way for the caustic, and measure the distance for the armed bougie, must be made of soft materials, that it may readily receive an impression from the part against which it is pressed, and its colour should be light, so as to admit of those impressions being more distinctly seen. With the assis- tance ol such bougies, I am able to discover the size and shape of the orifice of the stric- ture ; to ascertain with accuracy the progress of the caastic upon it; to see whether it is on one side of the canal, or equally nil round and to apply the caustic accordingly. “ When the soft bougie passes through the stricture, by leaving it in the canal a few minutes, it can be kqown whether the stric ture is completely destroyed or only relaxed ; in the last case, there is an impression on the side of the bougie.” (Home on Strictures , vol. 1.) CURE OF STRICTURES WITH TIIE POTASSA FUSA- Mr. Whately, in his publication on slric tures, endeavours to convince the reader URETHRA- that they are uot merely contracted fibres of the urethra, but really diseased portions of the membrane lining that canal, with a con- tinued disposition to increased contraction. Hence this gentleman seems to conceive, that the application of a remedy, calculated both to remove, the diseased affection, and to dilate the contracted part, might perfectly cure the complaint,' without putting the pa- tient to the inconvenience of wearing a bou gie. Mr. Whately affirms, that such a reme- dy is caustic, when judiciously used. Hither- to the lunar caustic has been chiefly employ- ed ; but this gentleman states, that it has been his good fortune to discover a more effi- cacious, and at the same time a less painful and hazardous remedy for the disease in ques- tion. The potassa^usa is the application al- luded to, which IVm Whately says, if used in the manner and with the precautions about to be described, will be found to pos- sess singular efficacy in curing the complaint. He avows, that he has already had so much experience of it, and that be is so perfectly convinced of its superiority over the lunar caustic, as well as over the common bougie, that he now use3 it in a considerable number of the cases which come under his care. Of its safety he is also as well convinced as of its efficacy ; for if used with circumspection, experience proves that there is little danger of its producing any disagreeable effect. However, if the potassa fusa be applied while the parts are in a highly inflamed, or irritable state, or (as Mr. Whately expresses himself) tending to gangrene ; if the habit be bad, and the patient very far advanced in years, the most mischievous effects may be expected from the application ; and the U3e of any kind of caustic, under such circum- stances, for strictures in the urethra, is cen- sured as dangerous in the extreme. Mr. Whately represents, that if the patient be affected with fever, or any other acute disease ; if he be much indisposed from any cause ; if, in particular, he have a gonorrhoea, attended with much inflammation and irrita- tion in th< urethra; if the prepuce, glans, or any other part of the penis, or the parts ad- joining to it, be swelled and inflamed ; if the urethra, and especially the strictured part of it, be so irritable as uot to bear the touch ot a bougie ; the use of the caustic is for the present forbidden. Mr. Whately also en- joins great caution in applying this remedy to persons advanced in years. Even when no objections of the above kind exist, the caustic should not be resorted to in the first instance. Mr. Whately maintains, that in every case of stricture, before venturing to employ the caustic, we ought to be able to pass into the bladder a bougie of at least a size larger than one of the finest sort. This is necessary, both to let the caustic^be applied to the whole surface of the stricture, and to relieve a retention of urine, should it oc- cur during the use of the caustic. When a bougie of the preceding descrip- tion can be introduced, without occasioning pain, faintness, or great dejectiou of spirits, ? he use of caustic may commence itnmedi- 54A ately, provided none of the above -described objections exist. When the urethra is very irritable, Mr. Whately recommends a common bougie t© be introduced every day, and kept in the urethra ; at first, for a few minutes only ; but by degrees for a longer time ; til i the irritability of the parts has been sufficiently lessened. When she urethra is rendered so impervi- ous by a stricture, that a small bougie cannot be passed into the bladder, which viscus is also in a painful inflamed state, Mr. Whately asserts, that caustic, in any form or quantity, must not be immediately employed ; but that the stricture should be first rendered ca- pable of allowing a bougie a little larger than one of the finest size, to be introduced into the bladder. When this is done, the urine is more freely evacuated, and the consequent irritation and inflammation of the bladder lessened, if not removed, together with the danger of • retention of urine. Caustic may then be advantageously conveyed into the centre of the stricture. Mr. Whately considers 'he practice of at once thrusting down, in this sort of case, an armed bougie considerably larger than the narrowest part of the contracted canal, as most dangerous, and horridly painful. For, says this gentleman, it frequently happens, that nearly the vs hide of the urethra anterior to the bulb is so much contracted by nume- rous, and uncommonly rigid strictures, that it is impossible, by any art whatever, to di- late the passage to its natural size. If, there- fore, the canal, whilst in such a slate, be rudely torn open by a large caustic bougie, hemorrhage, pain, dangerous suppressions of urine, inflammation, mortification, and death itself, must sometimes inevitably ensue, — even before the caustic can be applied to the principal seat of the disease. In cases like the one just mentioned, the first step prepa ratory to the use of the caustic should be, ac- cording to Mr. Whately, to dilate the strictu red part of the urethra; for which purpose, he advises the slow and gentle introduction of a fine bougie, with its point inclined to the lower side of the canal, in order to avoid the large lacunce situated on its upper part. When the surgeon, by steady perseverance and dexterity, has succeeded in getting a fine bougie through the worst stricture into the bladder, the instrument should be worn for a few hours every day, till the passage is suffi- ciently dilated to admit a larger one. Mr. Whately, after explaining that caustic potassa ought not to be applied to strictures of the urethra till a bougie of a proper size can be passed into the bladder, pointing out the methods to be taken before applying this caustic, and enumerating certain cases and circumstances in which its employment is interdicted, next proceeds to describe the mode of practice, which it is the particular object of his book to recommend. For the purpose of arming a bougie, Mr. Whately advises us to put a small quantity of caustic potassa upon a piece of strong paper, and to break the bit of caustic yvitii URETHRA. a hammer into small pieces of about the size of large and small pins’ heads. In doing this, care should be taken not to reduce it to powder. Thus broken, it should be kept for use in a phial, closed with a ground stopper. The bougie should have a proper degree of curvature given to it, by drawing it several times between the finger and thumb of the left hand. Mr. Whately next acquaints us, that be- fore the caustic is inserted into the bougie, it is necessary to ascertain the exact dis- tance of the stricture (to which the caustic is to be applied,) from the extremity of the penis. For this purpose, the bougie, which should be just large enough to enter the stricture with some degree of tightness, ought to be gently introduced into the urethra; and when its point stops at the stricture, which it almost always does be- fore it will enter it, a notch is to be made with the finger-nail on the upper or curved portion of the bougie, on the outside of the urethra, exactly half an inch from the ex- tremity of the penis. When the bougie is withdrawn, a small hole, about the sixteenth part of an inch deep, should be made at the extremity of its rounded end. A large blanket-pin, two inches and a half in length, with the head struck off, will answer the purpose ; the hole being made with the point of the pin. The extremity of ihe bougie should then be made perfectly smooth with the finger and thumb, taking care that, in doing this, the hole in its centre be not closed. Some of the broken caustic should then be put on a piece of writing paper, and a piece less in size than the smallest pin’s head should be selected ; the particle, indeed, says Mr. Whately, can- not be too small for the first application. Let this be inserted into the hole of the bougie with a pocket-knife, spatula, or some such instrument ; and pushed into it with the blunt end of the pin, so as to make the caustic sink a very little below the margin of the hole. To prevent the potassa fusa from coming out, the hole should then be contracted a little with the finger, and the remaining vacancy in it is to be filled with bog’s lard. This last substance (continues Mr Whately) will prevent the caustic from acting on the sound part of the urethra, as the bougie passes to the stricture. When the bougie is quite prepared, let it be first oiled, arid immediately afterward intro- duced, by a very gentie motion, with the curvature upwards as far as the anterior part of the stricture, upon which the caustic is to be applied. In doing this, the end of the bougie, held by the finger and thumb, should be a good deal inclined towards the abdomen, on the first introduction of the instrument, in order to prevent its curva- ture. After it has passed about five inches, this end should be gradually brought down- wards, as the bougie passes on, till it forms a right angle with the body. The bougie is known to have arrived at the stricture by the resistance made to its progress. As «oou as the bougie lias reached the anterior part of the stricture, it should rest there for a few seconds, that the caustic may begin to dissolve. It should then be pushed very gently' forward about one- eighth of an inch ; after which, there should be another pause for a second or two. The bougie should then be carried forward in the same gentle manner till it has got through the stricture. The sense of feeling will generally inform the operator when the point of the bougie has proceeded so far ; but the notch in the bougie is to be an ad- ditional guide, by becoming very near the orifice of the urethra when the end of the instrument has just got through the stricture The bougie should now be immediately withdrawn by a very gentle motion to the part at which it was forst made to rest awhile. Then it shouV be very slowly passed through the stricture a second time; but without letting the bougie stop in its passage. If the patient complain of pain, or be faint, the bougie should be immedi- ately withdrawn ; but, if these effects are not produced, we may repeat the operation of passing and withdrawing the bougie through the stricture once or twice more before we finish the operation, which will take up, in the whole, about two minutes. The first application of the potassa fusa, in this manner, gives, according to Mr. Whately’s account, a very little pain. A slight scalding in making water, and a tri- fling discharge during the first day or two, however, are commonly produced. At the end of seven days the application of the caustic is to be repeated in the same manner. When the first application has enlarged the aperture of the stricture, which may be known by passing a bougie through it of the same size as that by which the caustic was conveyed, the bougie used in the second operation should be a size larger than the one used in the first ; but it must not be too large to pass through the stric- ture. If the patient had no pain on the first application, the bit of potassa fusa may also be trivially larger. At the end of seven days more, the armed bougie should be in- troduced a third time. At this, and all future applications, the bougie should be increased in size in proportion as the aperture in the stricture becomes dilated. The quantity of caustic, however, is never to be increased in a ratio to the size of the bougie. In no cases whatever does Mr. Whately apply more of the potassa fusa at a time than a piece about the size of a common pin’s head. Twelve bits of the largest size, which this gentleman ever uses, weigh one grain. When there are several strictures, the potassa fusa should be generally applied to only one at a time. An interval of seven days is what Mr. Whately generally allows to elapse between the applications of the caustic. The rule, however, may now and then be deviated from ; but the potassa fusa ought never to be reapplied till the action of the last ap- plication has completely ceased. In a few URETHRA S4M instances, the interval may only be five days ; in some others, it may be eight, nine, or even a longer space. In the above method of using the potassa fusa, Mr. YVhately represents that this sub stance is equally diffused over every part of the strictured surface, and only abrades the membrane of the stricture, without produ- cing a slough. The degree of this abrasion, he says, may be increased or lessened as circumstances dictate, by paying attention to the quantity of the caustic. The foregoing account will suffice for conveying an adequate idea of Mr. Whate- ly ’s method. I am sorry I cannot add my favourable opinion of the practice. To abrade, without destroying, is rather too nice a distinction for a practical man, doing business as it were in the dark. Nor can 1 conceive, that a liquid caustic (for so it is represented as becoming) can be applied with the accuracy to strictures, which Mr. Whately seems to suppose happens. This, however, is merely my own sentiment ; and I do not wish to conceal that there are yet a few surgeons who believe that Mr. Whately’s plan is the most eligible. for all' cases, in which the stricture is irritable, or far advanced. (See Howship's Pract. Obs. on the Urinary Organs, p, 207.) On the other hand, I know some very eminent surgeons, who formerly took up this prac- tice with great zeal, yet now have entirely abandoned it. I consider it myself the worst and most random mode of applying caustic to strictures, and more likely to act on the sound than the diseased portion of the urethra. Upon the whole, I may safely declare, that caustic bougies are now much less frequently used by the best surgeons in London than they were about fifteen years ago; Several distinguished practitioners, who to my knowledge were then accus- tomed to recommend and employ them, have at present returned either to the use of common bougies, or those made of me- tal, or elastic gum, to which, after many comparative trials, I acknowledge, a gene- ral, but not universal, preference seems to me to be due. We learn from M. Roux, that caustic bougies never had many advo- cates in France ; and the inquiries which he made when he was in London autho- rized him to announce to his countrymen after his return, that such instruments are at present not more in general favour here than they are at Paris. (See Voyage fait a Londres en 1814, ou Par allele de la Chirur- gie Angloise, tye.p. 315.) Cases of stricture, however, where the disease is far advanced, of long standing, and attended with such obstruction that no kind of common bougie can be introduced, appear to me to be the examples in which the employment of bougies, armed with the nitrate of silver, ought principally to be con- tinued. This mode seems to me less vio- lent than that of employing a common bougie, or iron sound, with sufficient force to make it? wav through the stricture by laceration. It must also be attended with less risk of rupturing the urethra, and pro - ducing a false passage. At the same time, if the stricture occupy some length of the passage, and a common bougie, which is the best instrument in this circumstance, cannot be introduced through the obstruc - tion so as to dilate it, 1 believe a passage through it must often be attempted on the principle of exciting ulceration, and that for this purpose a sound or metallic catheter should be employed. In the first instance, however, 1 would try the armed bougie. 1 have already explained that the armed bougie has likewise been particularly re- commended for what has been termed the irritable stricture ; and it is even declared, in Sir Everard’s third volume, that lunar caustic has a greater power of removing spasm than any other kind of caustic. A Treatise on the Venereal Disease, by John Hunter, 2 d Edit. Practical Obs. on the Treatment of Strictures in the 'Urethra and (Esophagus, by Sir Everard Home, in 3 Vols. 8 vo. bond. An Improved Method of Treating Strictures in the Urethra, by Tho- mas Whately, Edit. 2, 1806. M. W. Andrews's Obs. on the Application of Lunar Caustic to Strictures in the Urethra and (Esophagus, 8r o. Lond. 1807. T. Luxmore's Practical- Observations on Strictures , fyc. 8i o. Lond. 1800. Howship's Practical Obs. on the Dis- eases of the Urinary Organs, 8 vo. Lond. 1816. Soemmering Abhandlvng fiber die schnell und langsam todtlichen Krankheitcn der Harnblase und Harnrohre bey Mannern im hohen Alter. 4 to. Frankf. 1800. Letters con- cerning the Diseases of the Urethra, by C. Bell , 1810 ; subsequently republished with ad- ditions by Mr. Shaw. James Wilson, Lectures on the Structure and Physiology of the Male Urinary and Genital Organs, and their Dis- eases, Svo. Lond. 1821.' James Arnott, a Treatise on Stricture of the Urethra, 8r c. Lond. 1819. Having given an account of this gentleman's dilator, and his method of treatment, .in the 2d Vol. of the lastlt> those of the abscess. When the extravasa- tion occupies the scrotum, long deep scarifi- cations should be made in that part, as well as in the skin of the penis, and in every place where the urine is effused. Practitioners, unaccustomed to see such diseases, would be alarmed at the extent of the sore produced by the separation of the eschars. Sometimes the whole scrotum, skin of the penis, and that of the groins, perinseum, and upper part of the thigh, mor- tify, and the naked testicles hang by the sper- matic chords, in the midst of t his enormous ulcer. It is hardly conceivable how cica- trization could take place over the exposed testicles; but the resources of nature are unlimited. She unites the testicles and the chords to the subjacent parts, and drawing the skin from the circumference to the centre of the ulcer, she covers these organs again, and furnishes them with a sort of new scrotum. This statement is founded upon numerous cases, in which nature al- ways followed this course. The cicatriza- tion of the ulcer is even more expeditious than might be apprehended, considering its extent. In all this business, what does art do? If the introduction of the catheter is excepted, which indeed is absolutely neces- sary for the radical cure, her assistance is very limited, and almost nothing, in the ge- nerality of instances ; for, when patients are not exhausted by the tediousuess of the disorder, when they are of a good constitu- tion, and in the prime of life, they get well as quickly and certainly with the aid of a good diet and simple dressings, as when they take internal medicines, and use a multiplicity of compound topical applica- tions. The practice of Desault at the Hotel- Dieu, consisted in applying emollient poul- tices, until the sloughs were detached. The ulcer was then sometimes dressed with pledgets charged with styrax ; but frequent- ly mere dry lint was used, and continued till the cure was completed. If any com- plication occurred in the course of the treatment, suitable remedies were prescri- bed for it. Thus, when prostration of strength and tendency to sloughing existed, bark, cordials, and antiseptics were ordered. But iu every case, the catheter is the essential means of cure ; without it, the treatment is almost always imperfect, and the ulcer will not heal without leaving several urinary fistulae. (See CEuvres Chir. de Default, par Bichat , T. 3, p.277— 287.) URINARY CALCULL A true explana- tion of the nature of urinary calculi was quite impossible, before chymistry had made considerable progress, and the methods of analysis had advanced a great way towards perfection ; and as will appear in the course of this article, all the valuable knowledge which now exists upon this subject, is in reality the fruit of modern investigations. It is to be regretted, however, that our in- formation on many points is far from being settled, or complete, as any impartial and judicious reader may soon convince himself bv a reference to the able and scientific views, lately taken by Dr. Prout, of various questions, relative to the formation of gra- vel and calculi, and the treatment of such cases in all their varieties. (See An Inqui- ry into the Nature and Treatment of Grave . and Calculus , and other Diseases connected with a deranged operation of the Urinary Or- gans, 8 vo. Lond. 1821.) Mechanical deposites from the urine are divided by Dr. Prout into three classes. 1. Pulverulent, or amorphous sediments. 2. Crystalline sediments, usually denominated gravel. 3. S'olid concretions, or calculi, formed by the aggregation of these sedi- ments. Pulverulent, or amorphous sediments , are described by Dr. Prout, as almost always existing in a state of solution in the urine before it is discharged, and even afterward until it begins to cool, when they are depo- sited in the State of a fine powder, the parti - cles of which do not appear to be crystal- line. Their colour js for the most part brown, or yellow, and generally speaking, they con- sist of two specie's of neutral saline com- pounds ; viz. the lithates of ammonia, soda, and lime, tinged more or less with the co- louring principle of the urine, and with the purpurates of the same bases, and consti- tuting what are usually denominated pink and laleritious sediments; and, secondly, the earthy phosphates, namely, the phos- phate of lime, and the triple phosphate of magnesia and ammonia, constituting for the most part sediments nearly white. The two species of sediments are frequently mixed together; though the lithates general- ly prevail. Crystalline Sediments, or Gravel, ore com- monly voided in the form of minute angular grains or crystals, composed, 1. Of lit hie acid, nearly pure. 2. Of triple phos- phate of magnesia and ammonia ; and, 3. Of oxalate of lime. The crystals of 1 it hie acid, which are by far the most frequent, are al- ways more or less of a red colour. Those composed of the triple phosphate of mag- nesia and ammonia are nearly white; while others, composed of the oxalate of lime,u hich are extremely rare, are of a dark, blackish, green colour. It is further remarked by Dr Prout, that ’these different varieties of crys- talline deposites are never voided together, though they not unfrequently occur with amorphous sediments. {Prout, Op. cit. p. 79, Solid Concretions, or Urinary Calculi, ari - sing trorn the precipitation arid consolidation of the urinary sediments, may be formed in any of the cavities 10 which the urine has access; and hence, they are met with in the kidneys, meters, bladder, and urethra Their various appearances, and chymical properties, will be presently described. Most of them are believed to be originally produced in the kidneys, from which they afterward descend with the urine. To this statement, however, the cases in which cal- culi are formed upon foreign bodies intro- duced into the bladder through the urethra, an accidental wound, or some ulcerated URINARY CALCULI communication between the intestines and the bladder, are manifest exceptions. In the centre jdi urinary calculi, bullets, splinters of bone, pieces of bougies, and wood, pins, needles, nuts, &lc. are frequently observed ; and it would appear, that a very minute substance is capable of becoming a nucleus ; a mere clot ef blood, ora little bit of chaff, if not soon voided, being sufficient to lead to the formation of a stone in the bladder The litbic acid itself is a common nucleus, even where the whole calculus is not of the same material. That many urinary calculi ore originally produced in the kidney, is certain ; first, from (he severe pain, which the passage of such foreign bodies down the ureter always excites ; and, secondly, from their being of- ten discovered in the infundibula and pelvis of that viscus after death. This last fact is well illustrated in the first plate of Dr. Mar- cel’s interesting “ Essay on the Chymical History and Medical Treatment of Calculous Disorders ,” 8 vo. 1817. The engraving is taken from a preparation in the Museum of Guy’s Hospital. In this instance, there were several calculi closely pressed against each other ; but in another example, drawn from a specimen in Mr. Abernethy’s muse- um, the renal concretion was composed of a single mass, which represented a complete cast of the pelvis and part of the infundibula of the kidney. In this form of the disease, the kidney loses at last all vestiges of its natural structure, and is converted into a kind of cyst, filled with the extraneous sub- stance. As Dr. Marcet observes, when such a complete alteration of the structure takes place, th« secretion of urine, must of course be entirely carried on by the other kidney. However, in some instances, the inconve nience thus produced is so slight, that it al- most escapes notice; and sometimes even both kidneys are diseased in a very great degree, and yet life is preserved for a con- siderable time. (Op. cit. p. 3, 4.) Calculi are sometimes found in the ureters, especially at the upper part ; but it is not supposed that they are originally formed there; an event not likely to happen, unless there were some cause retarding the descent of the urine through those tubes. The common belief is, that all calculi, found in the ureter, are first produced in the infun- dibula and pelvis of the kidney, from which they afterward descend with the urine. The generality of calculi, however, which leave the kidney, are of small size, and consequently, after a time, and exciting some pain and inconvenience, they usually pass into the cavity of the bladder. Indeed, as Dr. Marcet remarks, the bladder is the most frequent seat of calculi ; not only be- cause all urinary concretions, or their nuclei, formed in the kidneys, tend to fall into that organ ; but also because a stone may be, and probably often is, originally formed in the bladder itself. Rena! concretions vary considerably in their number, size, and shape. In some eases, a single small calculus has been 547 found occupying one of the foregoing situa- tions ; while in other instances, an innume- rable collection of calculous substances are observed filling the whole of the cavity of the pelvis and infundibula of the kidney, distending its parietes, and even obstructing the passage of the urine out of this viscus. which is converted into a sort of membra- nous cyst. Lastly, a single stone in the kid ney tnay acquire a very large size there ; or a great number of small caiculi, in the same situation, may become cemented together, so as to form one mass of enormous dimensions, and the shape of which invariably corres ponds to the space in which it is, as it were, moulded. Hence, renal calculi often present a variety of odd, irregular figures, resembling those commonly observed in specimens of coral. It has been already remarked, that urina- ry concretions of large size very often exist in the kidney, without their presence being indicated by any external circumstances, or attended with any symptoms, sufficiently unequivocal to constitute a ground for sus- pecting the importance of their cause. On the other hand, it is very usual for renal ca! culi, of middling dimensions, to excite seri ous and alarming complaints. The reason of this difference becomes obvious, when it is recollecied, that smallish concretions are readily carried with the urine into the ureter, and become fixed in the narrow por tion of the tube. But very large calculi can he contained only in the upper part of this canal, where its parietes are more yielding, and the space in them more capacious. Calculi, of middling size, in their passage through the ureter, cause at first, a feeling of heaviness, or an indeterminate sense of uneasiness, and an obtuse pain in the region of the corresponding kidney. These com- plaints occur at intervals of greater or less duration. At length the pain grows more urgent and annoying, attended with flatu lence, heart-burn, frequent vomiting, pain- ful retraction of, the testicle, and sometimes acute fever. The patient makes water fre- quently, and in small quantities at a time ; and the urine is high-coloured and bloody The patient cannot sit upright, his body being bent forwards towards the affected side. These symptoms may have more or less du- ration, and then suddenly cease. They may also subside, and recur several times suc- cessively, with intervals of some day3. In the latter case, the pain is fell at each at tack to be situated lower in the track of the ureter. Lastly, when the symptoms have entirely disappeared, the urine is more abundant, not so high-coloured, and easily discharged, the stream sometimes bringing out with it the urinary concretion, after its entrance into the bladder. Suppuration of the kidney, and an abscess in the lumbar region, in consequence of re- nal calculi, are not very common events However, these are the only cases of the kind, in which the interposition of surgery can be useful. By adverting to previous cireum stances, and irregularity of the pain about URINARY CALCULI •>'18 The kidney, tiie pracl it ioner may suspect the nature of a phlegmonous tumour in the situation of this viscus. Whatever may be his conjectures, however, he must carefully abstain from the use of his lancet, until pu- rulent matter is plainly under the integu- ments. He may then safely make an open- ing, from which urine and pus will be dis- charged, and through which the calculi themselves may sometimes be felt and ex- tracted. If they should not be readily touched with a probe, let not the surgeon rashly conceive, that he is justified in en- deavouring to discover them with his knife. Their situation may be such as to baffle all his endeavours, and the operation itself might cause a most dangerous hemorrhage, and other fatal mischief. The opening of an abscess of the kidney may remain a long while fistulous, and the circumstance indeed warrant the conclusion, that the fiealing is prevented by the presence of some extrane- ous substances ; but a prudent practitioner will never think of performing any opera- tion for their extraction, unless they can be distinctly felt, and nature has brought them tolerably near to the surface. (See Nephro- tomy.) Urinary calculi, which form upon foreign bodies, accidentally introduced into the blad- der, and acting as nuclei, are a!-.\ ays single, unless the number of foreign bodies them- selves happen to be greater. It is curious also to find, from the observations of Mr. Murray Forbes, (On Gravel and Gout, p. 74, 8 ro. Lond. 1793,) and Dr. Marcet, that in such instances the deposition most frequent- ly, if not always, consists of the earthy phos- phates, and especially of the fusibie calculus. Thus, in the collection of Mr. R. Smith, of Bristol, there is a pin, a piece of bougie, and four pieces of stick, coated with fusible mat- ter. (See Med. Chir. Trans. Vol 11, jo. 11.) But when calculi originate from a particular diathesis, there may be many of litem lodged in the bladder at the same time. Several distinct nuclei may descend successively from the kidneys, and each may increase in a separate manner. Sometimes, however, calculi in the bladder, which are at 'first dis- tinct and unconnected, become afterward cemented together, so as to make only one mass. The magnitude of calculi in the bladder is generally in an inverse ratio to their num- ber. Sortie hundreds have been found in one bladder; but they were not larger than a pea. It is observed Uy Sir AstUjy Cooper, that when a great number of calculi are found in the bladdery the circumstance is ge- nerally attended vvitn an enlargement of the prostate gland, directly behind which a cal- culus is formed. In cases of diseased pros- tate gland, the bladder can seldom be com- pletely emptied, and this partial stagnation of the urine in the sac, here alluded to, is supposed to facilitate the production of cal- culi. From their number and collision against each other, their surfaces are gene- rally smooth, and their shape is commonly roundish, (bjee Med. > Chir. Trans. Vo! 11 , p. 359, and art. Prostate Gland.) Other cal- culi have been met with of so large a size, that they were more than six inches in dia meter. In Fourcroy’s museum, and in that of the Ecole de Medeeine, at Paris, may be seen some calculi, which filled the whole ca- vity of the bladder ; and in the Phil. Trans, fur 18G9. the late Sir James Earle described an enormous stone, which he extracted after death from the bladder of the late Sir David Ogilvie, who had been unsuccessfully cut for it. This calculus, which was of the fusible kind, weighed forty-four ounces, and was of an oval shape, its long axis measuring sixteen inches, and the shorter fourteen. The average size of vesical calculi may be compared with that of a chesnut, walnut, or a small hen’s egg. The size depends very much upon their composition, the largest being of the fusible kind. Their weight differs from a few grains to upwards of fifty ounces ; but on an average, it is from two to six ounces. Their weight is not always proportioned to their size; for substances of different qualities enter into their composition, and diversify their hea- viness. The urinary salts, in calculous patients, are not continually precipitated in the same quantities: in some cases, indeed, the pro- cess appears to be even suspended for a considerable time. Hence a stone of mid- dling size, already formed, may increase but very slowly, and it has actually happened, that a calculus, which could be plainly felt with a sound, has remained more than ten years in the bladder, and yet, after all this time, been only of a moderate size. According to Dr. Marcet, the form of urinary calculi is mostly spheroidal, some- times egg-shaped, but often (lattened on two sides, like an almond. (P. 50.) Sometimes the calculous matter, which descends from the kidneys, is in the form of minute sphe- rical grains, which have a singular tendency to unite either to each other, or to calculi already lodged in the bladder. When there are several loose calculi in the bladder together, they seldom lie long in contact with each other, while their size is diminutive, but are incessantly changing their situation as the patient moves about, or alters the position of bis body. Hence their increase is at first regular and uniform : but when they have attained a more consi- derable size, or by their numbers compose a large mass, their relative situation is more permanent, and many of their surfaces be- ing in this manner usually covered, no longer receive any additional depositions. Every other part of these calculi, however, goes on increasing. It is thus that stones, with surfaces corresponding to those oi other stones, are produced, and which are aptly denominated by the French writers, “ pier res h face lies." Dr. Marcet lias likewise taken notice oi the angular shape of certain calculi, and re- marked the rare occurrence ot their being sometimes almost cubic. His work con tains the engraving of a species of calculus. URINARY CALCULI 549 which somewhat resembles a pear, with a circular protuberance at its broader end, apparently moulded in the neck of the blad- der. The same intelligent writer has also par- ticularly considered the variety in the co- lours and surfaces of calculi, which often alford indications of their chymical nature. “ When they have a brownish, or fawn colour, somewhat like mahogany wood, with a smooth, though sometimes finely tu- berculated surface, they almost always con- sist of lithic acid. When cut open, they appear to be formed of concentric layers, sometimes homogeneous, sometimes alter- nating with other substances. The colour, however, cannot be considered as a .certain criterion, since other kinds of calculi may often be coloured in the bladder, in a simi- lar manner, by bloody mucus, or other vi- tiated seerelions. :i When calculi are white, or gravish- white, they always consist of earthy phos- phates. This is particularly the case with the species called fusible. And when they are dark brown, or almost black, hard in their texture, and covered with tubercles, or protuberances, they are generally of the species which has been distinguished by the name of mulberry , and consists of oxalate of lime. “ Calculi have sometimes an uneven, crystalline surface, studded with shining, transparent particles. This appearance al- ways denotes the presence of the ammo- niaco-magnesian phosphate.” ( Marcet , p. 52.) A large calculus, especially when it has a rough irregular surface, produces a great deai of irritation of the bladder, which con- tracts more clasely round it. The contact, however, is remarked to be particularly ex- act at the transverse line, which extends between the terminations of the two ureters in the bladder ; a part of this organ which generally becomes more thickened than the rest. Sometimes, indeed, the cavity of the bladder is nearly effaced, and the urine can be retained only a very short time, or if it be not evacuated, it spreads uniformly round the calculus, especially above and below the above-described transverse projection, which is less yielding than other parts of this organ. Hence, the surface of the stone, towards the orifices of the ureters, does not enlarge so fast as the other sides of it, and a circular groove is produced, giving the foreign body the shape of a calabash. Such calculi are generally very large, and some- times even of enormous size. In the latter circumstance, the foreign body fills the ca- vity of the bladder so completely, that there is no space left for the lodgement of t lie urine there, which fluid then generally passes along a sort of groove, situated in a line reaching from the lower termination of the ureter to the neck of the bladder. This' state is of course accompanied with a com- plete incontinence. Urinary calculi are not always loose and moveable in the cavity of the bladder : be- ing sometimes fixed in various ways to cer- tain points of the circumference of this organ ; a subject, w hich has been noticed in the article Lithotomy . When the bladder protrudes from the ab- domen, so as to form a hernia, a stone is occasionally situated in the displaced por- tion of it. This circumstance has the same effect as the encysted state of a calculus : for the foreign body is thereby fixed, and it cannot be propelled towards the neck of the bladder at the period when the urine is dis- charged. Also, in cases of prolapsus uteri T when the bladder is drawn downwards, a stone has sometimes been found lodged at the low est part of it. The possibility of the complication of a calculus, with such dis- placements of the bladder, ought to be well remembered, since, if the nature of the case be detected, its treatment becomes mate- rially simplified. The symptoms of a stone in the bladder have been detailed in the article Lithotomy ? and therefore need not here be repeated. They are all so equivocal, and bear so great a resemblance to the effects of several other disorders, that they cannot be depend- ed upon, and consequently no well-informed surgeon will venture to pronounce positive- ly, that there is a calculus in the bladder, unless he can distinctly feel it with a sound. (See Lithotomy and Sounding.) As for the operation, if the surgeon cannot plainly feel the calculus immediately before he com- mences the incisions, it ought to be post- poned. Notwithstanding the laudable zeal, With which various distinguished physicians and surgeons of the present day, have applied themselves to the consideration of the causes of urinary calculi, the subject is yet in great obscurity. The conjectures which have been started, respecting the influence of particular kinds of food, drink, air, and habits of life, are all Of them liable to such objections, as throw" considerable doubts on their correctness, and sometimes amount to a decided refutation of them. If a foreign body be introduced into a cavity, to which the urine has access, what- ever may be the nature of the immersed substance, it always becomes after a time incrusted with calculous matter, though it undergoes no chymical change in its com position. In such cases, it is found (See Forbes on Gravel and Gout, 8 vo Lond. 1793, and Marcet on the Chymical Hist., tyc. of Calculous Disorders, 8 vo. Lond. IS 1 7.) that the concretion mostly, if not always, con- sists of the earthy phosphates. Mere, the operation of any particular diathesis is be- yond all suspicion, because theforeign body , which forms the nucleus, would lead to the production of a calculus in all descriptions of patients. There are some countries, where patients with calculi are tolerably numerous; and other parts of the world, where the disease is rare, or never met with ; and yet the dif- ference cannot always be accounted for by any geographical circumstance, which is URINARY CALCULI, 550 constant, ov any definable peculiarity of constitution, climate, diet, or mode of life. One fact, however, I believe is certain, viz. tiie uniform rarity of the disease in very hot countries. In tropical climates, urinary cal- culi are almost unknown, and, as Dr. Mar- cet observes, the testimony of Dr. Scott on this point, who long resided in India, must be considered valuable. Dr. Scott affirms* that, between the tropics, he never met with a single instance of the formation of a stone in the urinary bladder, although he knew of some cases which had been im- ported, and were not cured by climate. (See Marcel on the Chymical History and Med. Treatment of Calculous Disorders, Chap. 2, 8t’o. Load. 1817.) Yet, as calculi fre- quently form on various nuclei, bullets, pieces of bougies &c. I conceive, that, even in India, calculi will some day or another be found to originate from this cause, though not perhaps from diathesis. Urinary calculi are said also to be very un- common in Spain and Africa, though pa- tients with gravel are numerous in Majorca, which lies between them. ( Magendie . Re- cherces sur les Causes, fyc. de la Gravelle, p. 31, 8vo. Paris , 1818.) The usual belief is, that calculi are most frequent in damp, cold countries, like England and Holland, but, that in such other parts of the. world, as are either very hot or cold, the disease is rare. However, in every estimate of this kind, the number of the inhabitants of the countries, or districts in question, is always an essential thing for consideration, because the propor- tion of stone-patients, in a given number of individuals, is invariably rather small ; and, therefore, in referring to the rarity of such patients in very cold countries, it is to be considered, whether the fact may not be, in some measure, ascribable to the fewness of the inhabitants. The state of medicine and surgery, in the countries from which the in- formation is transmitted, is likewise another thing for contemplation, inasmuch as pa- tients are not likely to be reported as suf- fering from, or dying of stone, where the nature of diseases is not scientifically ob- served, morbid anatomy is uncultivated, and the operation of sounding never attempted However, as our East India native regi meats are furnished with excellent surgeons, I consider it well proved that in those regi- ments the disease is uncommon, for other- wise the statement would no doubt have been contradicted by them. The fact seems therefore well established, in relation to the East Indies. At the same time, the ages of the individuals, to whom any calculation applies, is always to be taken into consider- ation, before any inference be drawn re- specting tile cause of the rarity of calcuii, because, if the disease be rare among sol- diers in India, it is also rare among soldiers xn Europe, and therefore climate would not explain the fact in both parts of the world. But, probably, the recollection, that com- mon soldiers are neither children, nor men, above the middle period of life, and that the first, formation of stone in yoylhs, adults. and middle-aged persons, is uncommon, unless some extraneous substance happen to enter the bladder and form the nucleus, may furnish a reason for the infrequency of the disease among soldiers, applicable per- haps to siich individuals in every country. And that the children of soldiers, like those of other persons, are not exempt from the disease, I know very well, having had oc- casion myself to operate upon a patient of this kind during my service with the army The preceding consideration also of the general age of sailors in the royal navy, and of the little chance there must be of a boy with s'one beii.g sent to sea, or of any sailor being admitted on board of a King’s ship with that disorder, unless it be wilfully con- cealed by the man himself, furnish to my mind a better explanation of the cause of so few cases of stone having been met with among seafaring persons, than any of the references to the habits or mode of life of a sailor, made by Mr. C. Hutchison in his in- genious paper. (See Med. Chir. Trans Vol 9, p. 448, fyr.) From this gentleman’s ac- count it seems, that out of 86,00< patients, admitted into the Naval Hospital at Haslar. Plymouth, and Deal, in the space of sixteen years, there has only been eight calculous cases, or one in 10,750 patients. Two of these cases were boys, about fourtten years of age, “ who had laboured under symptoms of stone for some years previously to their admis sion into the service, and into which they had recently entered , expressly for the purpose of deriving benefit from our magnificent institu- tions ; one was a marine who had been at sea a few months only ; three were adult seamen, and the seventh a marine ; but tlieir length of service afloat could not be at all as- cer tamed .- the eighth, and last case, was a warrant officer, advanced in years , who had been serving in ordinary, that is, in a ship in harbour for a considerable time previ- ously to the operation.” Subsequently to the period, embraced by the returns col- lected by Mr. C Hutchison, a boy has also been operated upon in Haslar Hospital. ( Vol. cit. p. 449.) Mr. R. Smith, of Bristol, has published an interesting statistical in- quiry into the frequency of stone in the bladder in Great Britain and Ireland, though strictly it is a comparative estimate of the number of operations for stone in different parts of the kingdom in given spaces of time, and not of the number of calculous patients. (See Med. Chir. Trans. Vol. 11.) As far as I can judge from the facts sta- ted in Mr. Smith’s paper, and from what I know about the average number of ope- rations for stone in London, not more than 180 can be fairly reckoned as the an iiu ah total in Great Britain and Ireland, which is about 1 for each 100,000 of the population, taken at 18 millions. Now, if this fact be recollected, in computing the rarity of stone operations in the navy, and the other circumstances of there being few children and old men in that service, and of every man btiing examined by a surgeon, to the state of his health, before, be is rn i;kinaky calculi tered, 1 think the reason of the infrequency of stone in the navy will be tolerably clear. However, as sailors live partly in very hot and partly in very cold climates, even if they were of the ages most subject to cal- culi. they may perhaps be rather less dis posed to the complaint, than individuals of the same periods of life, constantly resident in England In the cold country of Swe- den, urinary calculi are said to be infre- quent. (Riche rand, Nosogr. Chir T. 8, p. 528, Ed. 4. ;) and, as surgery is there highly cultivated, the uncontradicted statement weighs considerably in favour of the truth of the general belief in the rarity of this disorder in very cold countries. But, as I have already said, the number of inhabit- ants, to which any particular evidence on this point relates, is an essential inquiry, before a safe inference can be drawn. It is perfectly well ascertained, that the greater number of urinary calculi are com- posed chiefly of lithic, or uric acid, which is naturally contained either in a free or com- bined state in the urine of man, and all other animals, which consume a great deal of food abounding in azote, as flesh ojf every kind, fish, shellfish, eggs, &ic. Whenever the urine will redden the tincture ot turnsol, Magendie infers with the generality of chy- mists, that it contains lithic acid, the pro- portion of which, he says, varies according to the quantity of substances abounding in azote, taken as food. And Magendie further observes, that when animals live altogether on flesh, their urine is full of uric acid, and even may be entirely composed of it, as is proved with respect to birds, by the experi- ments both of Dr. Wollaston and Vauquelin. Here Magendie cannot mean free uric acid, but this acid in a state of combination ; for, as Dr. Prout has observed, there is no in- stance known, in which lithic, or uric acid is secreted in a pure state ; birds, serpents, &,c. always secrete it in combination with ammonia ; in the gouty chalk-stone, it is secreted in combination with soda. (On the Nature, fyc. of Gravel and Calculus, p. 13.) On the contrary, if animals live on vegeta- bles, as is the case with the herbivorous class, Magendie states that there is no ap- pearance of lithic acid in their urine. In a series of experiments, communicated by Magendie to the Academy of Sciences in 1816, this distinguished physiologist exem- plified, that if a carnivorous animal be de- prived of all nutriment, containing azote, and be fed with sugar, gum, oil, and other substances considered to be nutritious, and having no azote in their composition, the urine, in three or four weeks, will contain no lithic acid. (See Mem. sur les Proprteles nutritives des Substances, qui nc contiennent pas d'azote. Paris, 1817.) A dog, allow-ed only sugar, and distilled water, soon began to grow lean, and died apparently starved on the 32d day from the commencement of his diet. The inference which Magendie draws from his experiments, aud from some cases which he has detailed, is, that the quantity of uric acid in the urine, and of «i51 course, the tendency to gravel and calculous disorders, depend very much upon the kind of food. However, he takes into consider- ation the relative propoition of the uric acid to the urine itself, because if this be also abundant, the liability to calculi is counter .acted. It would appear also from his obser- vations, that the urine not only becomes impregnated with a great proportion of uric acid in animals, which eat a large quantity of flesh, but is also scanty ; arid that, on the other band, a vegetable diet always pro- motes the secretion of a large quantity of fluid from the kindneys, as well as check- tbe formation of the acid in question. Ma- gendie is also disposed to believe, that the rarity of calculi in hot climates may be partly traced to the kind of food employed. In fact, it is well known, that, in a consider- able part of Asia, many millions of the inha- bitants never eat flesh. But, though this circumstance must be allowed to have full weight, with respect to the sects which re- ligiously decline animal food, the influence ot climate cannot be rejected, because cal- culi are rare in all hot countries, w r hethev meat be freely eaten or not. At the same time, the tenor of this gentleman’s reason- ing may be true, that, setting out of the question the influence of climate, a vege table diet tends to prevent the formation of lithic acid calculi, while eating large quan- tities of such food as contains a greal deal of azote, has the opposite effect. However, Magendie himself is not so par tiat to his theory, as not to confess that it is liable to objections ; for, says he, individu- als are met with every day, who from their age, manner of living, and habits, appear to be subjected to every condition, calculated to produce the gravel, and yet they remain free from it. Hence he infers, that there must be some unknown causes which some times keep the uric acid dissolved, even where its quantity in the urine is copious. On the other hand, he admits that certain persons are met with, whose regimen and mode of life ought to exempt them from gravel, and still they are afflicted. In proof of this fact, he adverts to^ the poor inhabit- ants of a district in Sussex, mentioned by Dr. Scudamore, (On the Nature and Cure of Gout, fy-c. Svo. Land. 1817.) who live almost entirely on vegetable matter and hard beer, aud many of whom are much troubled with gravel. Magendie might also have recol lected, that some birds which live entirely on vegetable matter, as several singing birds kept in cages, void a good deal of the lithate of ammonia. Magendie refers to examples of gravel being always produced in certain individuals after any unusual exertion, and in other apparently healthy subjects, after any difficulty of digestion, flatulence, the eating of salad, raw fruit, &c. With regard to the dyspepsia, frequently attendant on calculous disorders, and other chronic dis- eases, Magendie sets down the complaints of the stomach and of the urinary organs, as probably only two effects of the same cause, and not. mutually productive of each other URINARY CALCULI (See Rechercius , «V" • sar ' es Causes, fye. dc la Gravelle ■ 8 to. Paris, 1818 .) It should he observed, that Mageudie’s observations are meant to apply only to ca- ses of gravel, and where the substance void- ed is 1 it hie acid. And as for other instances, in which the calculous matter is formed of phosphate of lime, oxalate of lime, cystic oxide, &x. he deems the causes entirely un- known. One thing is certain, that Magen- die’s theory will not account for the origin of calculi, unless a predisposition to the dis- ease from other unknown or conjectured causes be taken as a matter of fact. Indeed, this admission he makes himself; and he enumerates various circumstances conducive to gravel, besides a diet of food abounding in azote ; as advanced age, a sedentary life, and hard study, long retention of the urine in the bladder, strong wines and liquors. In fact, without the predisposition, arising from unknown causes, and particular periods of life, a meat diet will not render the occur- rence of calculi frequent, as is exemplified in sailors, who eat a great deal of salt beef and pork. And, on the contrary, that the eatmg of little.' or no animal food will not always prevent the formation of calculi, when there is tendency to it from time of life, diathesis, or other causes, is sufficiently proved by the frequency of the disease in infants, in whose food there is a much smaller proportion of meat and azotic sub- stances than in the usual. diet of an adult. With respect to amorfdious sediments, the circumstances which Dr. Prout has observed to produce a lithic acid diathesis in per- sons, subject to slight dyspepsia, but in other respects healthy, are, 1, Simple errors in diet. 2, Unusual, or unnatural exercise, either bodily Or mental, particularly after eating, and the want of proper exercise at all other times. 3, Debilitating circumstan- ces. (On Gravel , Calculus, tyc. p. 113.) An unusually heavy meal, especially of animal food, or bread, he says, is invariably follow- ed by a deposition of the lithate of ammo nia from the urine. Heavy, unfermented bread, and compact, hard boiled, fat dump- lings, or puddings, he finds particularly apt to produce such an effect. Crystallized sediments, or gravel, consist- ing of nearly pure lithic acid, Dr. Prout as- cribes to a free acid being sometimes gene- rated in the kidneys, and combining with the ammonia, with which the lithic acid is previously united, so as to precipitate the latter in a pure crystallized state. Accord- ing to the investigations of Dr. Prout, the precipitating acid is not constantly the same, though generally the phosphoric, and sometimes the sulphuric. (P. 1 :7, 128.) The same intelligent writer represents, the circumstances, which promote the formation of urinary sediments in general, as being either natural or acquired. - £ With respect to those of the first description, (says he) it cannot « think be doubtmi, that certain individuals are much more liable to these sediments than others. This tendency is not infrequently inherited 'thus, I know a family, where the grandfather ;fnd father have actually lithic calculi in the bladder ; and where the grandson, a youth of twelve, or thirteen years of age, has a very strong tendency to the same disease ; his urine de positing frequently very large quantities of lithic acid, both in the form of amorphous and crystalline sediments. On the other hand, the disposition to generate these sedi- ments in excess is, like gout, or rather si- multaneously with gout, but too frequently acquired by indolent habits, and excess in eating and drinking. Most frequently, how- ever, the tendency to these diseases is con nected with some unknown causes, peculiar to certain districts or countries,” as, for ex- ample, the district, of which Norwich may be considered as the centre ; in which more calculous cases occur than in the whole of Ireland or Scotland. In such instances the water, diet, temperature, &c. of the district has been each accused, in its turn, of being the exciting cause ; bnt, (says Dr. Prout) the circumstance, I believe, still remains unexplained. I have in one or two instan- ces seen a fit of lithic gravel iuduced in the predisposed by sitting on a damp cold seat for some hours. Sometimes also a tenden- cy to lithic calculus is evidently connected with lo.^al injury, or disease of the kidney.” (P. 133.) The difficulty of tracing the causes of the formation of calculi is rather increased, than facilitated, by the fact, that, except when the urinary organs are much diseased, the pa- tient may appear to be in perfect health. Indeed, persons of the strongest constitu tions are often troubled with the stone, quite independently of the entrance of any foreign body, as a nucleus, into the bladder ; and if is now universally admitted, that lithic acid itself constitutes by far the most com - mon nucleus, even when other calculou; matter is deposited round it. (See Prout on Grarcl, p. 95.) It is sometimes conjectured that the female is less liable than the male sex, to calculi ; but whether this is the fact, or whether the circumstance can be satis- factorily explained on another " principle, viz. the facility with which any calculi of moderate size are generally discharged through the short and capacious meatus urinarius,are questions perhaps not yet com- pletely settled Infants and children to the age of twelve, or fourteen, are very liable to stone. How- ever, it is asserted by Delpech, that at this period of life, relapses are infrequent; that is to say, an entirely fresh stone is hardly ever formed again ; arid, if a return of the complaint happens, the quickness of its re- currence, and an attentive examination of the calculus, will mostly' prove, either that the second stone has formed round a frag- ment of the first left behind, or that it ex- isted when the former one was taken out, but was not discovered. I am not inclined myself to put much faith in this statement, because it is hardly credible, that the calcu- lous diathesis of childhood can be at all diminished bv the circumstance of there UKINAItV CALCULI having already been one calculus, and of the patient having had the bladder opened for its removal. Dr. Marcet thinks, that the disorder is frequent only among the children of the poor classes; and that in those of the high- er ranks, or even of the lowest classes, pro- vided they arc well fed , the same frequency is not observed. “ In the Foundling Hos- pital, for instance, within the last 27 years, during which 1151 children have been ad- mitted, only 3 cases of stone have occurred, all of which were among children while at nurse in the country. And, in the Military Asylum at Chelsea, which contains about 1250 children, and into which upwards of 6000 of them have been already admitted, no more than one single case of stone has occurred ” (See MarceVs Essay on Calcu- lous Disorders, p. 36 ) However, supposing that the foregoing statement refers to ope- rations for stone, and that the average number of operations for the population oi Great Britain and Ireland, is annually about 1 for each 100,000 inhabitants, the inference drawn by Dr. Marcet, which also does not agree with later statistical reports, cannot be received, because in the total number of children, specified as having been admitted into the above charities, even when every allowance is made for the time comprised in the calculation, the proportion of opera- tions is far beyond the average, with refer- ence to the population in general. And, that stone cases are more numerous in the children of the poor, than in those of the higher classes, is a fact, which perhaps may be explained by the recollection, that the mass of the population consists of the poor and laborious classes. In the period of life, between the age of twelve, or fourteen, and that of forty, the liability to stone in the bladder, is much less than in infancy, childhood, or old age. And no doubt, many of the cases, which do present themselves in adults, or middle aged individuals, either began at an earlier period of life, or are owing to some extraneous nucleus. According to Delpech, in old men, who are particularly subject to calculi, the dispo- sition to the return of the disease always continues during life ; and hence in them, relapses are frequent. {Pricisdts Mai. Chir. T. 2, p. 193, fyc.) The following table, collected by Dr. Prout, exhibits the proportion of stone cases before and after puberty, and of their occur- rence in the different sexes : isting of. |Females 44 C/l , a m o o u ^ o 5 O) Ox © H i C iO -d a U3 — 1 . ©> 03 f' o o Cl Cl o 'Z. ©> -1 r~- O Oi © Cj — ; CO i'- to i - r- to 03 23 o ,c ~ 3 tft —l * m — « a o cj > Thus, nearly one half of the whole number of stone cases occur before the completion of the 14 th year ; and it appears also from Mr. Smith’s valuable reports, that there is an evident increase in the number of cases, about the age of 40 years. (See Prout on Gravel, tyc. p. 210; and R. Smith , in Med. Chir. Trans. Vol. 10.) Dr. Marcet has estimated the comparative frequency of the disease in various coun- tries, and in the different stations of life, and tried to ascertain, w'bether its frequency be influenced by varieties of climate, or situation, or by peculiarities in our habits and occupations. He instituted inquiries at all the great hospitals of the metropolis, in the hope of getting at some useful records concerning the vast number of patients, on whom lithotomy had been performed in those establishments. In London, he found it impossible to obtain all the particulars of such cases, as no entry of them had been preserved. The Norwuch hospital, however, afforded him some details, udiich are inter- esting. All the calculi, w'hich have been exracted in that hospital for 44 years, viz. from 1772, to 1816, and which amount to 506, have been carefully preserved, with the circumstances annexed to each stone, and the event of the operation distinctly recorded. Dr. Marcet has given the results of these records in the following table : Vofc, II 0 URINARY CALCULI. CO 00 f- Gl — o Oi Ci tr 1X1 CJ 2fa It appears, says Dr. Marcet. from the above table, that the mean annual number of cases of lithotomy in the Norwich Hos- pital, during the last 44 years, has been 11 1-2, or 23 in every two years ; and that the total number of fatal cases, in the 506 operations- is 70, or 1 in 7 1-4, or 4 in 29. The proportion of females, who have under- gone the operation, is to that of males, as 58 to 1000, or about 1 to 17 ; that the mor- tality from the operation in children was oniy about 1 in 18; while, in adults, it was 4 in 19, or nearly quadruple. According to Mr. Smith,, the mortality from lithotomy at the Bristol Infirmary, has been in the following proportions: Age. 10 years of age and under Between 10 and 20 20 30 40 50 60 70 30 40 50 60 70 SO Mean at all Ages Rate of Mor- tality. 1 in 4 1-2 1 — 5 1 — 7 1 — 5 1-3 1-8 1 — 4 2-3 1-2 1-2 1 —2 I in 4 1-4 The following table is also from Mr. Smith’s paper, and refers to the Leeds Hos- pital. (See Med. Chir. Trans. Vol. 10.) ] Cases of | Lithotomy. From 1767 to 1777124 of whicli 1777 1787162 1787 1797123 1797 1807 42 1807 1817146 Mean at all ages, died >r I in 12 1 7 3-4 1 7 2-3 1 6 1 5 3-4 1 in 7 4-5 In the Norfolk Infirmary the mortality has been much less in children, than in adults. But at St. Bartholomew’s, the proportion of deaths in children, during the 20 years that I frequently attended operations for stone there, was very great. In the Bristol Infir- mary, the risk in children seems to have been about equal to what it has been in adults. In all calculations of this kind, how- ever, it is to be recollected, that as opera- tions for the stone are done, not oniy by surgeons of various degrees of skill, but in dilferent ways, and even with instruments of great diversity, such computations do not give the fair average of any one method of operating. Now, where the patients are equally favourable, but the results of any given number of operations on them are consider- ably dilferent, the skill of the surgeons, the particular methods of operating pursued, the kinds of instruments used, the general health- iness of the hospital itself, and the treatment after the patients are put to bed, are consi- derations, by which questions, apparently in- explicable, might sometimes he solved. From the year 1772 !o 1816, the Norwich Hospital received 18,859 patients of all kinds, making an average of 428 annual ad- missions ; and Dr. Marcet observes, that the proportion of 50.6 operations of lithoto- my, out of 18,859 patients, which corres- ponds to about 1 in 38, exceeds in an as- tonishing degree, that obtained from any of the other public institutions, whose records he examined. Next to the records of the Norwich Hos- pital, Dr. Marcet derived the most distinct information of this kind from Cheselden, who mentions in his work on anatomy, that during the course of his public practice in St. Thomas’s Hospital, a period of about 20 years, he had performed th’e operation of the stone 213 times, and lost only 20 patients. This was about 2 cases in 21, which is much less than the common average. In St. Thomas’s Hospital, during the last ten years, the operation of lithotomy seems to have been done, on an average, 11 times in each two years ; and one case of stone has occurred in eacli 528 patients admitted. In St. Bartholomew’s, lithotomy was per- formed 56 times in the years 1812, 1813, 1814, 1815, and 1816 The annual average about 11, or 1 in each 340 patients of all descriptions. In Guy’s Hospital, lithotomy has been performed, on an average, about 9 or 10 times annually, during the last 20, or 30 years. The proportion of calculous patients there is also estimated as 1 in about 300 cases of all kinds. Dr. Marcet’s inquiries incline him to think, that on the whole, lithotomy in the London Hospitals for some years, has been gradually becoming less frequent ; and this lie con- ceives may be owing, partly to a real reduc- tion in the frequency of the stone, from some . Iteration in the diet, or habits of the people ; partly to* the use of appropriate medicines ; and partly to the circumstance URINARY CALCULI. t>5 6 of calculous patients not resorting so exclu- sively, as was formerly the case, to the great London hospitals for -the operation. In the Royal Infirmary at Edinburgh, the average number of stone cases annually, during the last six years, is said not to have exceeded 2, although about 2000 patients are admitted there every year. Dr. Marcet has been informed by M. Roux, that, in La Charite at Paris, ten or twelve cases of stone occur every year, out of about 2600 patients, and that the propor- tion of deaths from the operation there is 1 in 6 or 6. In the HOpital des Enfans Malades, in the same city. Dr. Marcet. states, on the authority of Dr. Biett, that about 6 cases of stone are received every year into that establishment, where about 3000 children of both sexes are annually admitted. There have been only 3 cases in females, and what is remarkable, only two deaths from the operation in the course of the last se- ven years. Dr. Marcet was acquainted, that lithotomy is comparatively rare at Vienna, not on ac- count of the want. of good surgeons, or the unfrequent occurrence of stone cases in that part of the continent ; but in consequence of the little attention paidjo this disease by the most eminentsurgeonsofthe Austrian capital. At Geneva, says Dr Marcet, in a popula- tion of 30,000, lithotomy has been perform- ed only thirteen times in the last twenty years, though good surgeons are never wanting in that town to perform the opera- tion whenever an opportunity presents itself. Out of these thirteen patients, seven were not strictly Genevese, though belong- ing to the neighbouring districts, and one was an Englishman ; so that the disease would, at first sight, appear to^be a rare oc- currence at Geneva. But, continues Dr. Marcet, if the smallness of the Genevese po- pulation be taken into account, this propor- tion of calculous cases may not fall very short of that observed in other places. At Lyons, a populous town, not more than eighty miles distant from Geneva, the dis- ease is stated to be rather frequent. With regard to the chymical nature of urinary calculi, there was nothing known until 1776, when Sc'neele published on the subject in the Stockholm Transactions. He there stated, that all the urinary calculi, which he had examined, consisted of a pe- culiar concrete substance, now well known by the name of lithic, or uric acid, which he also showed was soluble in alkaline lixi- via. Scheele further discovered, that the lithic matter was, in some degree, capable of being dissolved in cold water; that this solution possessed acid properties, and, in particular, that of reddening litmus; that it was acted upon in a peculiar manner when boiled in nitric acid ; and lastly, that hu- man urine always contained this substance in greater or less quantity, and often let it separate in the form of a brick-coloured sediment, by the mere, effect of cooling. The disooverv made by Scheele was con- firmed by Bergmann and Morveau,and the investigation of the subject was afterward prosecuted by others with redoubled ardour As Professor Murray observes, experiments continued to be repeated and diversified on these concretions, anti on their solvents. At length it was fully ascertained, that there existed others, besides those compo- sed of uric acid; and, latterly, our know- ledge of them has been much extended by the researches of Pearson, Wollaston, Four- croy, and Vauquelin. Several important facts have also been- established by the ta- lents and industry of some other distinguish- ed men ; viz. Dr. Henry, of Manchester ; Professor Brande, of the Royal Institution of London ; Dr. Marcet late of Guy’s Hos- pital ; and Dr. Proul, of London. The facts and considerations of the latter writer ren- der it probable, however, that, the common opinion of pure lithic acid being contained in the urine is not exactly correct ; but that this acid <£ in healthy urine exists in a state of combination with ammonia, and that, in reality, this fluid contains no uncombined acid at all.” (On the jYaturc, fyc. of Gravel and Calculus , c. 13.) The credit which is due to Dr. Wollaston for his valuable and original discoveries, respecting urinary calculi, is very consider- able; a truth which I have particular plea- sure in recording here, since his merits have not been faifiy appreciated by the French ehvmists. Indeed, as Dr. Marcet observes, it is the more desirable that his claims should be placed in the clearest point oi view, as the late celebrated M. Fourcror, both in his “ Systerae des Connoissances Chimiques,” and in his various papers on this particular subject, has, in a most unac- countable manner, overlooked Dr. Wollas- ton's labours, and, in describing results, ex- actly similar to those previously obtained and published by the English chymist, has claimed them as his own discoveries. Yet. Dr. Wollaston’s was printed in our Philoso phical Transactions, two years before Four- croy published his Memoir in the w Annales de Chimie.” and three years before he gave to the world his “ Systeme des Connoissan- ces Chimiques;” and he discussed in these works a paper of Dr. Pearson on the lithic acid, published in a volume of the Philoso- phical Transactions (for 171)8) subsequent- to that which contained the account of Dr. Wollaston’s discoveries! (See Marcel's Essay on Calculous Disorders, p 60. Also Murray’s Syst. of Chyw . vol. 4, p. 6)6, edit, of 1S09.) It would appear then, that Scheele fir. discovered the nature of those urinary cal- culi which consist of lithic acid ; but that Dr. Wollaston first ascertained the nature of several other kinds, some of which have also been described at a later period by Fourcroy and Vauquelin. On the whole, there are five species of concretions, whose chymical properties were first pointed out. by Dr. Wollaston, and no less than four be- long to the urinary organs. These are, 1st. Gouty concretions. 2dly. The fusible (■■■'■ cuius. 3dly. The mulberry calculus. 4thly. •The calculus of the prostate gland. Gthly. The cystic oxide, discovered in 1810. 1. Lithic Acid Calculus. Dr. Front be- lieves that, at least two-thirds of the whole number of calculi originate from lithic acid ; for, as it forms by far the most common nu- cleus, round which other calculous matter is subsequently deposited, if such huclei had not been formed and detained, two persons at least out of three who suffer from stone, would never have been troubled with the disorder. (On Gravely Calculus, fyc. p. 95.) Lithic Acid forms a hard, inodorous con- cretion, of a yellowish, or brown colour, similar to that of wood of various shades. According to Professor Murray, calculi of th is kind are in fine, close layers, fibrous, or radiated, (and generally smooth on their surface, though sometimes a little rough. They arc rather brittle, and have a specific gravity, varying from 1,276 to 1,786, but usually above 1,500. One part of lithic acid is said to dissolve in 1720 parts of cold water, and 1150 parts of boiling water; ( Marcel , p. 65.) and this solution turns ve- getable blues to a red colour. When it has been dissolved in boiling water, small yel- lowish ((crystals are deposited as the fluid becomes cold. Lithic acid calculi blacken, but are not melted by the blowpipe, emit- ting a peculiar animal smell, and gradually evaporating, until a small quantity of white ash remains, which is alkaline. By distilla- tion, they yield ammonia and prussic acid. They are soluble in the cold, in a solution of pure potassa, ovsoda, and from the solu- tion a precipitate of a fine white powder is thrown down by the acid. Lime-water likewise dissolves them, but more sparingly. According to Scheele they remain unchan- ged in solutions of the alkaline carbonates ; a statement which agrees with that of Dr. Prout, who accounts for the effect said to be produced by the alkaline carbonates upon calculi in the bladder, by their pro- perty of dissolving the lithate of ammonia. (Egan in Trans, of Irish Acad. 1805, Prout on Gravel, tyc. p. 84.) They are not much acted upon by ammonia. They are not soluble either in the muriatic or sulphuric acid ; though they are so in the nitric when assisted by heat, and the residue of this so- lution, when evaporated to dryness, as- sumes a remarkably bright pink colour, which disappears on adding either an acid or an alkali. In many of these calculi, the lithic acid is nearly pure ; in others, there is an intermixture of other ingredients, par- ticularly of phosphate of lime, and phosphate of ammonia and magnesia ; and, in almost all of them, there is a portion of animal matter, which occasions the smell when they are burnt, and the loss in their analy- sis. (See Murray's Chymisiry, vol. 4, p. 640 ; and Marcel s Essay on the Chym. and Med. Hist. »f Calculous Disorders, Svo. Load. 1817.) A great quantity of uric acid is formed in gpiiiy constitutions, and deposited in the joints, or soft parts, in the state of lithate of ammonia. Sir Everard Home removed a tumour weighing four ounces from the heel of a gentleman, a martyr to the gout ; and when anatysed by Professor Brande, it was found to be principally composed of uric acid. (On Strictures, vol. 3, p. 313.) 2. Lithate of Ammonia Calculus, accord- ing to Dr. Prout, is generally of the colour of clay, f ts surface is sometimes smooth ; sometimes tuberculated. If is composed of concentric layers, and its fracture resem- bles that of compact limestone. It is ge- nerally of small size, and rather uncom- mon ; but the lithate of ammonia very fre- quently occurs, mixed with lithic acid, forming a mixed variety of calculus. Under the flame of the blowpipe it usually decre- pitates strongly. It is much more soluble in water than the lithic acid calculus ; and always gives off a strong smell of ammonia on being heated with caustic potash. The liihale of ammonia is also readily soluble in the alkaline subcarbonates, which pure lithic acid is not. (Prout on Gravel , fyc. p. 83.) 3. Bone Earth, Phosphate of Lime Calcu- lus. The presence of phosphate of limp in urinary calculi had been mentioned by Bergmaun and others, when Dr. Wollaston first ascertained, that some calculi are en- tirely composed of it. From the investiga- tions of Dr. Wollaston, it appears that this substance sometimes, though rarely, com- poses the entire calculus, but that in general it is mixed with other ingredients, particu- larly with uric acid, and phosphate of mag- nesia and ammonia. In the first case, the calculus is described as being of a pale brown colour, and so smooth as to appear polished. When sawn through, it is found very regularly laminated, and the laminae in general, adhere so slightly to each other, as to separate with ease into concentric crusts. It dissolves entirely, though slowly, in mu- riatic or nitric acid. Exposed to the flame of the blowpipe, it is at first slightly char- red, but soon becomes perfectly white, re- taining its form, until urged with the utmost heat from a common blowpipe, when it :nav be completely fused. It appears to be more fusible than the phosphate of lime, which forms the basis of bone; a circum- stance which Dr. Wollaston ascribes to the latter containing a larger quantity of lime. (Phil. Trans. 1797.) 4. Triple Phosphate of Magnesia and Am- monia Calculus . The existence of this cal- culus in the intestines of. animals was first pointed out byFourcroy; but its being a constituent part of some urinary calculi of the human subject, was originally discover- ed by Dr. Wollaston. (Phil. Trans. 1797.) According to Dr. Prout, t his species of cal- culus is always nearly white : its surface is commonly uneven, and covered with minute shining crystals. Its texture is not lamina- ted, and it is easily broken and reduced to powder. In some rare instances, however, it is hard and compact, and when broken, exhibits a crystalline texture, and is more or less transparent. Calculi composed entire- ly of the phosphate of magnesia and ammo. URINARY CALCULI uia are rare, but specimens, m which they constitute the predominant ingredient are by no means uncommon. ( Prout , p. S6.) When the blow-pipe is applied, an ammonia- cal smell is perceived, the fragment dimi- nishes in size, and it the heat be strongly urged, it ultimately undergoes an imperfect fusion, being reduced to the state ot phos- phate of magnesia. ( P . 69.) Ur. Wollaston describes the form of the crystals of this salt, as being a short trilateral prism, having one angle a right angle, and the other two equal, terminated by a pyramid of three or six sides. These crystals, as Dr. Marcet has ex- plained, are but very sparingly soluble in water, but very readily in most, if not all the acids, and on precipitation, they reas- sume the crystalline form. From the solu- tions of these crystals in muriatic acid, sal ammoniac may be obtained by sublimation. Solutions of caustic alkalies disengage am- monia from the triple salt, the alkali com- bining with a portion of the phosphoric acid. 5. Fusible Calculus. Mr. Tennant first discovered, that this substance was different from the lithic acid, and that, when urged by the blowpipe, instead of being nearly consumed, a large part of it melted into a white vitreous globule. The nature of the fusible calculus was afterward more fully investigated and explained by Dr. Wollas- ton. {Phil. Trans. 1797.) According to the excellent description lately given ot this calculus by Dr. Marcet, it is commonly whiter and more friable than any other spe- cies. It sometimes resembles a mass of chalk, leaving a white dust on the fingers, and separates easily into layers, or laminae, the interstices of which are often studded with sparkling crystals of the triple phos- phate. At other times it appears in the form of a spongy and very friable whitish mass, in which the laminated structure is not obvious. Calculi of this kind often ac- quire a very large size, and they are apt to mould themselves in the contracted cavity of the bladder, assuming a peculiarity of form which Dr. Marcet has never observed in any of the other species of calculi, and which consists in the stone terminating, at its broader end, in a kind of peduncle, cor- responding to the neck of the bladder. The chymical composition of the fusible calcu- lus is a mixture of the triple phosphate of magnesia and ammonia, and of the phos- phate of lime. These two salts, which, when separate, are infusible, or nearly so, xvhen mixed together and urged by the blowpipe, easily run into a vitreous globule. The composition ot this substance, says Dr. Marcet, may be shown in various ways. Thus, if it be pulverized, and acetic acid poured upon it, the triple crystals will be readily dissolved, while the phosphate of lime will scarcely be acted upon ; after which the muriatic acid will readily dissolve the latter phosphate, leaving a small resi- due, consisting of lithic acid, a portion of which is always found mixed with the fusi- ble calculus 5 At It is also remarked [by Dr. Marcet, that many of the calculi, which form round ex- traneous bodies in the bladder, are of the fusible kind. And the calculous matter sometimes deposited between the prepuce and glans is found to be of the same nature. 6. Mulberry Calculus , or Oxalate of Lime is mostly of a dark brown colour, its inte- rior being often gray. Its surface is usually uneven, presenting tubercles more or less prominent, frequently rounded, sometimes pointed, and either rough or polished. It is very hard, difficult to saw, and appears to consist of successive unequal layers : ex- cepting the few stones, which contain a proportion of silica, it is the heaviest of the urinary concretions. Though this calculus has been named mulberry from its resem- blance to that fruit, yet, as Dr. Marcet has observed, there are many concretions of this class, which, far from having the mul- berry appearance, are remarkably smooth and pale-coloured, as may be seen in plate 8, fig. 6, of that gentleman’s essay. Accor- ding to Mr. Brande. persons who have void- ed this species of calculus, are much less liable to a return of the complaint, than other patients, who discharge lithic calculi. {Phil. Trans. 1808.) With regard to chymical characters (says Professor Murray,) it is less affected by the application of the usual reagents, than any other calculus. The pure alkaline solutions have no effect upon it, and the acids dissolve it with great difficulty. When it is reduced however to fine powder, both muriatic and nitric acid dissolve it slowly. The solutions of the alkaline carbonates decompose it, as Fourcroy and Vauquelin have observed ; and this affords us the easiest method of analysing it. The calculus in powder being- digested in the solution, carbonate of lime is soon formed, which remains insoluble, and is easily distinguished by the efferves- cence produced by the addition of weak acetic acid, while there is obtained in solu- tion the compound of oxalic acid with the alkali of the alkaline carbonate. From this the oxalic acid may be precipitated by the acetate of lead, or of barytes ; and this oxalate, thus formed, may be afterward de- composed by sulphuric acid. Another me- thod of analysing this calculus is by expo- sure to heat : its acid is decomposed, and by- raising the heat sufficiently, pure lime is obtained, amounting to about a third of the weight of the calculus. According to Four- croy and Vauquelin, the oxalate of lime calculus contains more animal matter, than any other. This animal matter appeared to them to be a mixture of albumen and uree. '1 he composition of a calculus of this species analysed by Mr. Brande, was; oxalate of lime 65 grains; uric acid 16 grains ; phos- phate ot lime 15 grains; animal matter lour grains. 7. The Cystic Oxide Calculus is small, and very rare. It was first described by Dr. Wollaston. {Phil. Trans, for 1810.) In external appearance, it bears a greater re- semblance lo the triple phosphate of ma?- 558 URINARY CALCULI. nesia, than any other sort of calculus. However, it is more compact, and does not consist of distinct lamina?, but appears as one mas»<;onfusedly crystallized throughout its substance. It has a yellowish semi- transparency, and a peculiar glistening lus- tre. Under the blowpipe, it gives a singu- larly fetid smell, quite different from that of lithic acid, or the smell of prussic acid. In consequence of the readiness, with which this species of calculus unites both with acids and alkalies, in common with other oxides, and the fact of its also containing oxygen (as is proved by the formation of carbonic acid by distillation,) Dr. Wollaston named it an oxide, and the term cystic was added from its having been originally found only in the bladder in two examples. Dr. Marqet, however, has subsequently met with no less than three instances of calculi formed of cystic oxide, all of which were unquestiona- bly of renal origin. 8. Alternating Calculus. Lithic strata fre- quently alternate wkh layers of oxalate of lime, or with the phosphates. Sometimes also the mulberry alternates with the phos- phates, and in a few' instances, three, or even four species of calculi occur in the same stone, disposed in distinct concentric laminae. On the comparative frequency of these and other varieties of calculi. Dr. Prout’s work contains valuable infor- mation. 9. Compound Calculi , with their Ingredients intimately mixed. Under this title Dr. Mar- cet comprehends certain calculi, which have no characteristic feature, by which they can be considered as distinctly belonging to any of the other classes. He observes, that they may sometimes be recognized by their more or less irregular figure, and their less determinate colour; by their being less dis- tinctly, if at all divisible into strata ; and by their often possessing a considerable hardness. By chvmical analysis confused results are obtained. (See Essay on the Ckym. and Med. Hist, of Calculous Disorders, p. 90.) 10. Calculi of the Prostate Gland. The composition of those calculi is said to have been first explained by Dr. Wollaston. (See Phil. Trans, for 1797.) They all consist ot ohospbate of lime, the earth not being re- dundant as in bones. Their size varies from that of a pin’s head to that of a hazel nut. Their form is more or less spheroidal ; and they are of a yellowish brown colour. Fourcroy has described a species of uri- nary calculus, which is characterized by its being composed of the urate or lit hate of ammonia. Dr. Wollaston, Mr. Brande, and Dr. Marcet did not, however, satisfactorily ascertain the presence of this substance in any of the concretions, which they examin- ed. As also urea and the triple phosphate, both of which afford ammonia, are frequent- ly present in lithic calculi, it is conjectured, that these circumstances may have given rise to the analytical results, from which the existence of nratex>f ammonia has been in- ferred. {Brande in Phil. Trans. 1808. Mar- cet’s Essay, p. 93.) The recent investigations of Dr. Prout, however, tend to establish the reality of the lithate of ammonia calculus. Dr. Marcet has met with two specimens of urinary calculi entirely different from any which have hitherto been noticed. One of these he proposes to name Xanlhic oxide, from gavBoe, yellow , because one of its most characteristic properties is that of forming a lemon-coloured compound, when acted upon by nitric acid. The chymical proper- ties of the other new calculus, mentioned by Dr. Marcet, correspond to those of fibrine, and he therefore suggests the propriety of distinguishing it by the term fibrinous. For a particular description of these new sub- stances, I must refer to this gentleman’s Es- say. 11. Carbonate of Lime Calculus. This substance is not enumerated by Dr. Marcet, as entering into the composition of urinary calculi. But, according to Mr. R. Smith, there can be no doubt of the fact. Dr. W. H. Gilby of Clifton, he says, detected it de- cidedly in four instances. “ A notice of it will be found in Mr. Tillock’s Journ. for 1817, vol. 49, p. 188, in the account of a curious calculus, given to me by Mr. G. M. Burroughs, of Clifton ; the nucleus of which is a common cinder, an inch and a half long, and one broad. Since the publication of that paper (continues Mr. Smith,) Mr. H. Sully, of Wiveliscombe, sent me three oddly shaped calculi, which he removed from a lad, together with 15 pea-sized ones previously voided by the urethra, which are entirely carbonate of lime, held together by animal mucus.” (See Med. Chir. Trans, vol. l\,p. 14.) Dr. Prout has also seen some small calculi, composed almost entirely of carbonate of lime. {On Gravel , fyc. p. 89.) Dr. Prout has investigated with considera- ble talent the comparative prevalency of the different forms of urinary deposite, and the order of their succession. His data are taken from the examinations, made by Pro- fessor Brande, of the calculi in the Hunterian Collection ; by Dr. Marcet, of those at Nor- wich and Guy’s Hospital ; by Dr. Henry, of those at Manchester ; and by Mr. Smith, of others preserved at the Bristol Infirmary. The whole number of calculi examined was S23 ; of these, 294 were classed under the name of lithic acid. 98 of which were nearly pure; 151 were mixed with a little of the oxalate of lime ; and 45 with a little of the phosphates. 113 consisted of oxalate of lime. Three were of cystic oxide. 202 were phosphates ; of which 16 were nearly pure ; 84 mixed with a small proportion of lithic acid ; eight consisted of phosphate of lime nearly pure ; three of triple phos- phate nearly pure ; and 91 of the tusible or mixed calculi 186 were alternating calculi, or those whose lamina? varied, but consisted of lithic acid, oxalate of lime, and phos- phates: of these. 15 consisted of lithic acid and oxalate of lime, the first being in the creates t proportion : 40 of the oxalate of URINARY CALCULI inne in the greatest proportion, and lithic acid in the least ; 51 of the litbic acid and the phosphates ; 49 of the oxalate of lime, and the phosphates ; 12 of the oxalate of lime, litbic acid, and the phosphates ; one of fusible and litbic ; two of fusible, and oxalate of lime ; and 16, the composition of which was not mentioned. Of compound calculi, whose composition was not specified, there were 25. (See W. Front's Inquiry into the JVature and Treat- ment of Gravel and Calculus, p. 94.) The proportion of Hi hie acid calculi is somewhat more than one-third of the whole number. But as this acid is the common nucleus, round which other calculous matter is deposited, Dr. Prout computes the pro- portion of calculi originating from it, to be at least two-thirds of the whole number. According to the experiments of the same physician, the red crystalline calculus is composed of nearly pure lithic acid ; and the earthy, amorphous one, consists of lithic acid, more or less ammonia, generally a lit- tle of the phosphates, and sometimes a small portion of the oxalate of lime. The lighter the colour, the greater in geheral the pro- portion of lithate of ammonia and the phos- phates. (P. 97.) Oxalate of lime calculi form one-seventh of the whole number, without any regularity, however, in different museums. Cystic oxide calculi are so rare, that the proportion found was only one in 274. Calculi composed of the phosphates , made about one-fourth of the whole number. Alternating Calculi amounted to between one-fourth and one-fifth ; but, Dr. Prout oilers good reasons for believing, that the data, from which the estimate is drawn, cannot be depended upon. For additional information on this branch of the subject, I must refer to Dr. Prout’s valuable work. The stone being a severe affliction, and the operation extremely hazardous and pain- ful, a variety of experiments have been in- stituted for the purpose, of discovering a solvent for urinary calculi. Hitherto, how- ever, all the remedies and plans which have been tried, have been attended with very limited, and by no means, unequivocal •'iiccess, notwithstanding many persons may have been deceived into a contrary opinion. The dissolution of stones in the bladder has been attempted by lilhontriptic medicines, as they are termed, and by fluids injected into this viscus. At the present day, prac- titioners direct their endeavours very much to the correction of those particular diathe- ses, or states of the constitution, on which the formation of various calculi depend, and more confidence seems to be placed in this aim, than in any schemes for the dissolution of urinary concretions. It is certain, that in the latter project many difficulties present themselves, and among these, some of the most serious are the great variety in the composition of calculi ; the impossibility of knowing tbe exact ingredients of a stone, while it is concealed in the bladder, though many useful suggestions for assisting the judgment on this point have been recently 559 .otFered by Dr. Prout ; and lastly, if the right solvent were ascertained, as calculated upon chymical principles applied to urinary con- cretions out of the body, it is obvious, that any medicines, taken by the mouth, are lia- ble to so many changes in the alimentary canal, and in the lymphatic and vascular systems, that it must be exceedingly difficult to get them in an unaltered state and effect- ive quantity into the bladder; while, if this were possible (as it is in the way of injection through a catheter,) the bladder itself might be incapable of bearing the application, and the patient lose his life in the experiment. As Dr. Prout well observes, a calculus in the bladder may be considered a substance placed in a solution of various principles in a certain quantity of water. If any of the more insoluble of these principles exist in this solution in a state of supersaturation , the calculus will afford a nucleus, round which the excess will be deposited. But, if none exist in a state of excess, of course none can be deposited, and the calculus will not increase in bulk. Whoever studies the chymical properties of the urine, says Dr. Marcet, will learn, that “ if any alkali (a few drops of ammonia for instance.) be added to recent urine, a white cloud appears, and a sediment, con- sisting of phosphate of lime, with some am- moniaco-magnesian phosphate, subsidesln the proportion of about two grains of the precipitate from four ounces of urine. Lime water produces a precipitate of a similar kind, which is still more copious ; for the lime, in combining with the excess of phos- phoric, and perhaps also of lactic acid, not only precipitates tbe phosphate of lime, which these aeids held in solution, but it decomposes the other phosphates, thus ge- nerating an additional quantity of the phos- phate of lime, which is also deposited. “ It, on the contrary (observes the same author,) a small quantity of any acid, either the phosphoric, the muriatic, or indeed even common vinegar, be added to recent healthy urine, and the mixture be allowed to stand for one or two .ays, small reddish crystalline particles of lithic acid will be gradually deposited on the inner surface of the vessel. ‘ It is on these two general facts that our principles of chymical treatment ultimately rest. Whenever the litbic secretion predo- minates, the alkalies are the appropriate remedies ; and the acids, particularly the muriatic, are the agents to be resorted to when the calcareous or magnesian salts prevail in the deposite.” ( P . 147, 148.) The alkalies taken into the stomach cer tainly reach the urinary passages through the medium of the circulation ; and it is aiso strongly suspected that the acids like- wise do so, though this circumstance is still a question. Unfortunately, the quantity of either alkalies or acids, which thus mixes with the urine, is so small, that no impres- sion is made upon calculi of magnitude. The experience of Dr. Marcet, Dr. Prout, and others, however, has clearly ascer- tained that such medicines are often capable UIUJNAKY CALCULI. ' »jbU of checking a tendency to the formation of stone, and sometimes of bringiug on a cal- culous deposite depending upon the altered state of the system. Indeed Dr. Marcet ex- presses his decided opinion, that, even sup- posing not an atom of alkali or acid ever reached the bladder, still it would not be unreasonable to expect that these remedies may respectively produce the desired changes during the first stages of assimila- tion ; in one case, by neutralizing any mor- bid excess of acid in the primte vif urine ;. a maxim, which leads iiim to con- sider cutaneous perspiration injurious ; a statement which I think must be rejected, considering the rarity of calculi in hot cli- mates, independently of the sentiments of Dr. Wilson Philip, that the precipitating acid (if such be the cause) is thrown off by the skin, and consequently that insuring a due performance of the cutaneous func- tions, must, in these cases, be beneficial (See Medical Trans, of the College of Phy- sicians, Vol. 6.) 3. To prevent the lithic acid from assuming a solid form, by satu- rating it. 4. When gravel and calculi are formed, to promote their discharge and at- tempt their dissolution. ( Richerches , fyc. sur la Gravelle, p. 42.) For correcting the lithic acid diathesis, Dr. Prout particularly enjoins the avoidance of errors in diet, exercise, kc. The error of quantity of food, he deems worse than the error of quality. Patients, he say9, should abstain altogether from things which mani- festly disagree with them, and which must be unwholesome to all, such as heavy un- fermented bread, hard boiled and fat pud- dings, salted and dried meats, acescent fruits, and (if the digestive organs be debili- tated) soups of every kind. In general also wine, and particularly those of an acescent quality, should be avoided. The wearing of flannel, the preserving a regular state of the bowels, and the occasional use of alterative medicines, are likewise commended. (Prout on Gravel, <^c. p. 135.) According to the same author, the treat- ment of calculous affections is either of a local or general description. The local treatment is nearly the same in all the spe- cies ; the general treatment wall" depend upon the nature of the calculous diathesis. What Dr. Prout calls the local treatment consists chiefly in prescribing hyosciamus and opium, either alone or combined with, uva ursi. The hyosciamus, he says, is ge- nerally preferable in the lithic acid diathe- sis, and opium in the phosphatic. He also recommends the use of opium in the form of injection and embrocation, andespecially in that of a suppository. The warm bath, fomentations, and sitting over hot water, are spoken of as other means of relief. According to the observations of the same well-informed writer, the distressing symp- toms produced by lithic aci4 calculi have a very constant relation to the severity of the diathesis present ; a circumstance, which he says is also more or less true with re- spect to all the other kinds of calculi : that is to say, in proportion as the urine is unna- tural, and loaded with gravel and amor- phous sediments, in the same proportion, are the patient’s sufferings. Hence our first object should be to restore the urine to its natural state. The first means to be recom- mended, in ordinary cases, is usually a dose of calomel and antimonial powder, the Plummer’s pill, or some other alterative purgative, taken at night, to be followed up the next morning by an alkaline diuretic purgative, composed, for example, ot Bo chelle salts and magnesia, or subcarbona'e URINARY CALCULI oi soda During the day, a strong infusion of uva ursi. combined with hyosciamus and the liquor potassae, may be taken. These means ere to be persisted in for a greater or less time, according to the circumstances, and till the urine begins to be natural : they may then be gradually left off or varied, as occasion may require ; and, under this plan, it will be found, that, in the majority of cases, not only the urine will assume its natu- ral state, but most, or all the distressing symp- toms of calculus in the bladder, will be very ihitch diminished, and in many instances dis- appear. It is obvious also that, while the urine is in its natural state, the calculus cannot increase in size. “ After the diathesis is once fairly broken by these means, it may in general be easily prevented from recurring by attention to the diet, and other circumstances, formerly mentioned as inducing this diathesis, and by the occasional use of medicines ; and the patient will scarcely know that he has a calculus in the bladder, at least from the pain that it gives him. I state this with confidence ; but at the same time, I wish to be understood to mean, that the freedom from pain, &c. depend, in no inconsiderable degree, upon the size of the calculus, its smoothness, upon the exercise a patient is •obliged to take, &,c. all of which are pre- sumed to be favourable ; for it must be suf- ficiently obvious that a foreign substance in the bladder cannot be prevented from act- ing mechanically, and from occasionally producing bloody urine, or a temporary stoppage of the discharge of that secretion from the bladder, and similar symptoms, if the patient is obliged to take severe exer- cise.” ( Prout on Gravel, fyc. p. 202 — 204.) At the beginning of the eighteenth cen- tury, lime and the alkalies were known to be frequently productive of relief in cases of stone, and in particular the nostrum of a Mrs. Steevens, the active ingredients of which were calcined egg-shells and soap, acquired such celebrity for the cures which it effected, that much anxiety was expressed that her formula should be made public. The consequence was, that, in the year 1739, parliament appointed a committee of 22 respectable men to investigate the merits of the remedy in question ; and, on their very favourable report, the secret was pur- chased for the sum of 5000/. These pro ceedings naturally interested our neigh- bours, and in the year 1740 and 1741, Mo- rand communicated to the Academy of Sciences two memoirs, in which are report- ed numerous cases where the new remedy was tried, and mostly with success ; the greater number of the patients being de- scribed as either benefited or actually cured. In many instances, stones which had been unquestionably felt, were no longer to be discovered ; and as the same persons w^ere examined by surgeons of the greatest skill an i eminence, both before and after the ex- hibition of the medicines, it is no wonder that the conclusion was drawn that the Vor,. II 71 oO J stones had .been really • dissolved. Front the cessation of this success, however, and from its now being known that-stones occa- sionally become lodged in a kind of cyst, on the outside of the general cavity of the bladder, so as to cause no longer any mate- rial suffering, surgeons of the present da) are inclined to suspect, that this must have happened in Mrs. Stevens’s cases. Ihis was certainly what happened to one of the persons, on whom the above medicine was tried, as Dr. W. Hunter informs us. It is evident, that a stone, so situated, would not in general produce a great deal ol irritation, nor admit of being felt with a sound ; though, as l have stated in the article Lithotomy, there have been a tew exceptions to this observation. Mrs. Steevens first gave calcined egg-shell • alone; but, finding costiveness produced, she added soap. In time,, she rendered her process more complicated, adding snails burnt to blackness, a decoction of camomile flowers, parsley, sweet fennel, and the greater burdock. That, in the lithic acid diathesis, the car- bonated fixed alkalies, taken in large doses, have the effect of passing into the urine, and saturating the redundant lithic acid in the unhealthy state of that fluid, is a' fact deci- dedly proved. If there were any doub yet remaining upon this point, it would be immediately removed by the perusal oi the case of the celebrated Mascagni as detailed, by himself. (See Mem. della Soc. Ital. 1804.y This eminent anatomist being much afflicted with gravel, derived benefit from drinking the aqua alcalina mephitica, or Selzer Water , but, conceiving, that more good might result from a trial of carbonate of potash, he took, at first half a dram of this substance in the morning, and as much in the evening, dis- solved in ten ounces of water. The second dav, the dose was augmented to two drains, and on the third to three, which quantity dis- solved in 20 ounces of water, was continued for ten days. “ Before taking the carbonate of potash (says Mascagni) my urine was very acid, arid immediately reddened litmus paper: as soon as the medicine was begun, I made the same experiment with the urine, then voided, and found the intensity o.u the colour of the paper less. The second day, the paper was very little altered, and on le third, the urine did not redden it at all . -tup acid in my urine, therefore, was saturated, and, at the same time, the pain in my loins diminished, and no more gravel was voided with my urine. Afterward the pain ceased entirely, the urine became dearer, and I per- ceived that it contained an excess of potash. Being attacked again at a subsequent period with the gravel, Mascagni adopted the same treatment, and experienced equal benefit from it. In the lithic acid diathesis, the cauatic alkali, in the form of the liquor potassae. has sometimes been thought to have more em- cacy, than the carbonate. Sir E. Home and Mr. Hatchet first suggest- ed the utility of giving magnesia in cases f KLNARJfc CALCULI. of stone : aim ihe proposal was communica- led to the public by Mr. Brande (Phil. Trans . 1810.) As Dr. Marcet observes, magnesia is often found advantageous in long-protracted cases, in which the constant use of the sub- carbonated, or caustic alkalies, would injure t he stomach. But, he properly remarks, that, if magnesia is sometimes beneficial, it has of late years often done harm. For, as this earth is the base of one of the most common species of calculi, viz. that containing the phosphate of ammonia and magnesia, there is nearly an even chance, when magnesia is prescribed, without any previous knowledge of the nature of the calculus, that it will prove injurious. Magnesia, also, when long and profusely administered, sometimes forms large masses in the intestinal canal, causing serious distress, and even fatal consequences. According to Dr. Prout, purgatives wiil sometimes stop calculous depositions, espe- cially in children ; and Dr. Henry, of Man- chester, has observed that a quack medicine, composed of turpentine and opium, will oc- casionally produce a plentiful discharge of lithic acid from the bladder. On the whole, I believe, reason and expe- rience will aliow us to consider lirnewater, soap, acidulous soda water, the carbonate of potassa, the liquor potassa?, and magnesia, only as palliative remedies, by which the pain of the disorder may sometimes be diminished, and the urinary secretion im- proved, it being more rational to impute the few supposed instances of greater suc- cess to the calculi becoming encysted. As medicines, taken into the stomach, wiil not dissolve urinary calculi, solvent in- jections have been introduced through a ca- theter directly into the bladder. Fourcroy and Vauquelin ascertained, that a ley of potassa, or soda, not too strong to be swal- lowed, softens and dissolves small calculi* composed of the uric acid and urate of am- monia, when they are left in the liquid a few days. They proved, that a beverage, merely acidulated with nitric or muriatic acid, dissolves with still greater quickness, calculi,, formed of the phosphate of lime, and of the triple phosphate of ammonia and magnesia. They also ascertained, that cal- culi, composed of the oxalate of time, which are the most difficult of solution, may be softened, and almost quite dissolved, in nitric ■ acid, greatly diluted, provided they are kept in the mixture a sufficient time. Liquids are then known which will dissolve calculi of various compositions ; but, as I have already hinted, much difficulty occurs in employing, tliem effectually in practice, -.'or, although they can be easily injected into the bladder, this organ is so extremely tender and irritable, that the action of such liquidsupon it, as would be requisite for dis- solving a stone, would produce sufferings which no man could endure, and the most dangerous and fatal effects on the bladder i i self. Another objection to this practice also arises from the surgeon never knowing what il e exact composition of a calculus-is, be- ar this body is extracted, and his conse- quent inability to determine what solvent ought to be tried. Until the complete success of lithontriptics is established, therefore, the operation of lithotomy, severe and hazardous as it is, must continue an indispensable practice, whenever the patient s sufferings are great, and the calculus too large to be voided, or extracted through the urethra. In the early stage, however, before calculi have exceed- ed a certain size, if they cannot be expelled with the urine, they may sometimes be taken out by means of an instrument, invented by Mr. Weiss, of the Strand, shaped like a sound, but the end of which, after its introduc- tion into the bladder, admits of being opened and rnaife to grasp the calculus, which is then to be drawn through the urethra. The urine is first to be discharged through a ca- theter. (See an Account of a Case , in which numerous Calculi were extracted, without cut- ting Instruments , by Sir. A. Cooper, in Med- Chir. Trans. Vol. 11, p.349.) Consult T. Lobb, a Treatise on Dissolvents of the Stone, 8 vo. Loud. 1/39. Stephen Hales , Experiments and Observations on Mrs. Stee veils' s Medicines , 8 vo. Lond. 1741. Morand , ■in Mem. de l’ Acad, des Sciences, 1740, and 1741. J. Rutty, New Experiments on Joanna, Sieevens's Medicines , 8 vo. Loud 1742 R Why It, an Essay on the Virtues of Lime Wa-% ter and Soap, in the Cure of Stone, 8 vo Edinb. 1761. D. Hartley, a Vieiv of tliepre sent Evidence for and against Mrs. Sieevens's Medicine, 8 vo. Lond. 1739 ; and Supplement . 1740. N. Hulme, a safe and easy Remedy for the Stone, fyc.Ato. Lond. 1778 Wm. Butler , Method of Cure for the Stone, chiefly by injec- tions, 12 mo. Edinb. 1754. B. Langrisk, Phy- sical Experiments upon Brutes, in order to discover a safe Method of dissolving Stones in the. Bladder by Injections, 8vo. Lond. 1746. J Jurin , Effects of Soap-ley, taken internal hj for the Stone, ‘Id Edit, with an Appendix . 12 mo. Ixmd. 1745. J. F. Schreiber, De Me - dicamentosa J. Stcevens , contra calculum divul- gato inefficaci et noxio, Gi)tt. 1744. Murray Forbes, a Treatise upon Gravel and Gout , with an Examination of Dr. Austin's Theory of Stone, an Inquiry into the Operation of Sol- vents, fyc. 8 vo. Lond. 1793. W. Austin, a Treatise on the origin and component Parts of the Stone, fyc. 8 vo. Lond. 1791. T. Beddoes , on the Nature and Cure of Calculus , fyc. 8 vo. Loud. 1793. J. S. Dorsey, an Essay on the Lithontriplic Virtues of the Gastric Liquor. 8 vo. Philadelphia , 1802. M. Girardi, Dr. Ur a Ursina, ejusque el aqiue calcis vi lilhon - triplica, fyc. Patav. 1764. Schbele, in Stock- holm Trans. Fourcroy, in Systeme des Con- noissanccs. Ciiimiques . Wollaston, Pearson , and Brande, in Phil. Trans, and Journal of Science and Arts, Vols. 6 and 8, fyc. A. Marcet, on Vie Chymical History and Medical Treat - menl of Calculous Disorders, 8vo. Lond. 1 S 1 7 a work full of valuable information. Wilson Philip, in Medical Trans. Vol. 6. Dr. Henry , in Med. Chir. Trans. Vol. 10. C. Scudamore , on Gout, fyc. Edit. 3. F. Magcndie, Recher- ches Physiologiqucs et Medicates sur les Causes . fyc. dr la GraveV-r, 8vo, Paris, I^IK, A URINARY li'lSTUL/L Upland Hutchison, on the Comparative In- frequency of Urinary Calculi among Seafaring People , vid. Med. Chir. Trans. Vol. 9. A*. Smith , a Statistical Inquiry into the Frequency of Stone in the Bladder, in Great- Britain and Ireland, vid. Med. Chir. Trans. Pol. 11. IV. Front , an Inquiry into the Nature and Treat- ment. of Gravel, Calculus, fyc. 8 vo. Loud. 1821 ; a work abounding in original valuable observa- tions J. Wilson , on the Structure and Physio- logy of the Male Urinary and Genital Organ , and the Nature and Treatment of their Dis- eases, 8 vo. Loud. 1S21 ; this publication con- tains an excellent summary of the latest observations on the subject. URINARY FISTULiE. By an urinary fistula, strictly speaking, is implied a deep, narrow ulcer, which leads into some of the urinary passages : but, this name is likewise applied to sinuses, which, without having any communication with these passages, termi- nate near some point of their course. Thus, in Desault’s works, T. 3, p. 287,) three kinds of fistula?, in respect to the urinary passages, are noticed. The first Sort is called a blind external fistula, because it opens only exter- nally ; the second plind internal, because it has only one opening into the urinary pas- sages ; the third, is termed complete, being attended both with an internal opening into the urinary organs, and one or more external apertures. Among the blind external fistula?, only such as terminate near the canal of the ure- thra are particularly noticed in Desault’s works. All fistulas of this kind are originally owing to an abscess, that has formed in the vicinity of the urethra ; and. in the arti- cle Urinary abscesses, it has been explained, that these suppurations frequently originate from disease of that canal. Whatever may be the cause of these fistulas, however, it is not unusual to find, that, after the pus has made its way towards the scrotum or perineum, and discharged itself outwardly, the ulcer is converted into a sinus, which resists all the efforts of nature to heal it. One of the chief circumstances, tending to evince, that the sinus has no communication with the urethra, is, that no urine has ever escaped through the opening ; for, with re- spect to the' judgment formed from the im- possibility of making a probe touch a catheter in the passage, it must be exceedingly falla- cious, because the winding course of the sinus, or the small size of its communication with the urethra, may prevent the instru- ments from touching each other. According to Desault, the indications in the treatment of these blind fistula? depend upon the nature of their complications. When the sinuses are kept up by a separa- tion of the scrotum. from the parie es of the urethra, Desault recommends exact com- pression to be made over the part, which method, he says, is sometimes sufficient to accomplish a cure. When this plan fails, he states, that the healing ot the sinus may be promoted by practising an incision on one side of the scrotum, and carrying it as far as the denuded portion of the urethra. When sinuses exist, and they depend upon the smallness of the opening, or its un- favourable situation for the discharge of the matter, the aperture should be enlarged, by making an incision into the main collection of pus. When there are callosities, which resist cataplasms, and the most active re- solvents, Desault advises us to introduce into the fistula, trochees of minium, for the pur- pose of destroying the indurated parts. When the bones are diseased, exfoliation must be awaited ; and, in every instance, the treatment should vary, according to the cause, upon which the fistula depends. Blind internal fistulae, or such as communi cate with the urethra, but have no external opening, are sometimes produced in conse- quence of the bursting of an abscess into this canal ; the ulceration, from a retention of urine ; a false passage . and the healing of the external part of the wound made in lithotomy, while the internal part is not united. In these cases, there is a discharge of pus from the urethra, before, and sometimes after, the issue of the urine ; and one may feel, in the ^ourse of the urethra, a tumour, which increases while the patient is making water, and afterward disappears on pressure attended with a fresh discharge from the penis of a mixture of pus and urine. These internal urinary fistulae cannot be cured, except by preventing the urine from passing into them and lodging there. The catheters employed should be neither too large nor too small. If too large, they would exactly fill the canal, and the pus and urine contained in the fistula? could not be dis- charged. If too small, the urine would in- sinuate itself between them and the sides ot the urethra, and enter the fistula?. Their use must be continued till the ulcef is entirely healed. The most frequent urinary fistula? are those which are termed complete. Their origin may be in the ureters, bladder, or urethra. Those which arise in the ureters, sometimes terminate in the colon, and the urine is dis- charged per ahum mixed with the feces. But most commonly, these fistula? make their appearance* externally, either in the lumbar or inguinal regions. Those whicii communicate with the bladder, have also dif- ferent terminations. When they proceed from the upper and interior part of this or- gan, they ordinarily pierce the parietes of the abdomen above the pubes, and towards the navel. They also sometimes terminate in the groins. When they originate in the poste- rior parietes of the bladder^ they sometimes tend into the cavity of the abdomen, where they almost always prove mortal ; and some- times into the intestines, if there should be adhesions between these and the bladder, so as to favour this communication. When the opening in the bladder is near the bottom of this viscus, the fistula sometimes terminates in the rectum of ihe male, and the vagina of the female subject; but most frequently it ends in the perineum, in both sexes. With regard to the fistula? which originate in the 564 URINARY FISTULA. urethra, they usually open externally in the perimnurn, the scrotum, or the penis, and sometimes alsto in the rectum. It is not un- common to see the external opening of these fistula? at a great distance from the internal one, and to find it in the middle, and even the lower part of the thighs, the groins, pa- rietes of the abdomen, and as high as the sides of the chest. Often there is only one opening in the urethra, while there are seve- ral situated externally, more or less distant from one another. Most of these fistula? are the consequences of a retention ot urine, and are owing to the same causes as the diseases of Which they are a symptom. Those which cornvnu- ni< ate with the rectum, in the male subject, sometimes depend upon this intestine having been wounded in the operation ot lithoto- my ; and those which open into the vagina are often the effect of a violent contusion, caused by the head of the child in difficult labours, or of ulceration produced by pessa- ries, which are too large, and ihe margins of which are too sharp and irregular. Carcino- ma of the rectum aud vagina also give rise to fistula?, by extending into the bladder. The discharge of urine from the external orifice of the fistula, is an unequivocal proof of its communication with the urinary pas- sage ; when the fistula is narrow, arid there is no obstruction in the urethra, the urine some- times escapes more readily the latter way than through the fistula. It may also be dif- ficult, or even impossible, to find out the in- ternal orifice of the fistula with a probe. When the fistula communicates with the rec- tum or vagina, a staff introduced through the urethra may sometimes be fell in those parts. When fistula of the bladder or urethra are the consequences of a retention of urine, produced by strictures, which still exist, or have even increased since the formation of the fistula, the circumstance may render the introduction of the catheter difficult. In this sort of case, if the catheter cannot be pass- ed, the surgeon must endeavour to remove the stricture with bougies, on the principles) explained in the article Urethra , Strictures of. “ In general, (as Sir Everard Home ob- serves,) where fistula? take place in perina?o, in consequence of a stricture, the removal of the stricture is sufficient to give the fistula a disposition to heal. There are, however, cases which require more being done for that purpose, and simply laying them open is not sufficient.” (See Fistula in Perinceo.) Un- der such circumstances, Sir Everard Home finds the actual cautery the surest means of making the part heal In one case, he pass- ed a bougie into the urethra, and seared the edge of the fistula with a hot wire, introdu- ced as far as to touch the bougie. In another instance, a full-sized silver sound was passed into the bladder, and the direction of the fistula having been ascertained with a probe, a female steel sound was heated to redness, and “ at the moment at which it passed from a red to. a black heat, it was hurried down through the fistula (about two inches and a half) to the sound in the urethra. In both these cases a cure was effected. ( Home on Strictures , Vol. 3 , p. 262, fyc.) ■ When fistulae terminate in the lower part of the bladder, Desault advises the utmost care to be taken to prevent the catheter from being stopped up, and to hinder the instru- ment from becoming displaced, or slipping out of the bladder ; for which last purpose, the catheter bracelet described by Sir E. Home seems well calculated. However, when the fistula communicates with the ure- thra, Desault believes that no advantage would be derived from keeping the catheter open. In both cases, Desault recommends us to continue the catheter, not only until the fistula is cured, but also until the obsta- cles which binder the urine from passing the natural way are removed. Fistulae of the bladder, communicating with the vagina, and produced by difficult labours, are almost always attended with loss of substance. The forcible contusion, occa- sioned by the child’s head, on the anterior parietes of the vagina and bottom of the bladder, gives rise to the formation of sloughs, the separation of which • sometimes ieaves apertures large enough to admit the finger, and hence the difficulty of the cure. In treating such fistulae, there are two indica- tions to be fulfilled : 1st, to hinder the urine from passing into the vagina : 2dly, to keep the edges of the division as closely as possi- ble together, so as to give them an opportu- nity of uniting. In women, the introduction of the cathe- ter is easy ; but the instrument is more diffi- cult to be fixed than in men. Desault con- tends, however, that it is very essential to have it so fixed in the bladder that the urine may escape. He found that the only effect- ual plan was to fasten the catheter to a point that always retained the same position, with respect to the meatus urinarius. He used a kind of machine, made after the manner of a truss, the circle of which was long enough to embrace the upper part of the pelvis, and had in its middle an oval plate, intended to be placed upon the pubes. In the centre of this plate was a groove, to which a piece of silver was fitted, curved so that one of its ends, with an aperture in it, came over the vulva, on a level with the meatus urinarius. This piece of silver admitted of being fas- tened to the plate with a screw. After the catheter had been introduced and arranged in the bladder, so that its beak and eyes were situated at the lowest part of tin's viscus, the end of the instrument was put through the aperture of the piece of silver which slided into the groove of the plate, and it was af- terward fixed in the way already explained By means of this machine, the catheter was securely fixed, without incommoding the pa- tient, even when she was walking. In these last cases, large catheters, with full-sized apertures, should be employed, so that the urine may more readily escape through the instrument, than tall into the vagina. In the early part of the treatment, URINARY FISTULA:. otio the catheters should also be left constantly open. In order to keep the edges of the division as near together as possible, Desault intro- duced into the vagina a soft kind of pessary, large enough to fill the vagina, without dis- tending it. By this means, the form of the fistula was changed from round to oval, whichis the most favourable to its reunion; and the advantage was gained of closing the fistula, and hindering the urine from falling into the vagina. When the rectum is wounded in lithotomy, Desault advised dividing the parts compre- hended between the wound of the operation, the opening in the rectum, and the margin of the anus. That such an operation may become necessary in some instances. I will not say ; but it can never be proper until it is seen whether the wound of the rectum will hot heal up favourably without such treatment. I have seen two cases, in which the rectum was cut in lithotomy, yet no fis- tula ensued ; and other similar facts iiave been mentioned to me by professional friends. The success also with which the wound has generally been healed after lithotomy, done through the rectum, is another fact tending to prove, that the inconveniences of a wound of the latter bowel in the operation have been rather exaggerated. In a case of urinary fistula, co nmuni- cating with the rectum, and which could not be healed with the catheter. Sir A. Cooper introduced a catheter into the blad- der, and his finger into the rectum, and then made an incision, as in the operation for the stone, in the left side of the raphe, until he felt the staff through the bulb. He then di- rected a double-edged knife across the peri- neum, between the prostate gland and the rectum, with the intension of dividing the fistulous communication between the urethra and the bowel. A piece of lint was intro- duced into the wound, and a poultice applied. When the lint was removed, the urine was found to take its course through the opening in periiujeo ; the aperture in the rectum gra- dually healed ; and that in the perineum quickly closed ; the urine being all now dis- charged in she natural way {A. Cooper , Surgical Essays, Part 1 ,p. 215.) As the same gentleman has observed, aper- tures in the urethra, attended with loss of substance, are extremely difficult to heal. He relates a case where the urethra had sloughed at the junction of the scrotum with the penis; the opening healed at its margin, but a large fistulous orifice still remained. Bougies, the plans ol excoriating the edges of the opening with blistering plaster, and even paring them off, and bringing the fresh cut surfaces together with the twisted »u;ure, had all been tried in vain. In this example a cure was affected by applying the nitrous acid to the edge of the fistulous orifice, and to the skin, three quarters of an inch around it, the principle on which Sir A. Cooper rest- ed his hopes ot success, being the contrac- tion of the skin in cicatrization. The fir.-t application having produced considerable amendment, the plan was repeated several times in the course of about nine months, ai the end of which time the fistula was closed But Sir A. Cooper is ol opinion, that such practice will only succeed in cases where the skin is very loose, and the scrotum forms a part of the fistulous orifice. If the skin be much confined, he suggests raising a piece of skin from the scrotum, paring off tiie edges of the fistulous orifice, and removing the skin to a small extent around it. The skin thu - raised is to be turned half round, so that its raw surface may be .applied to the open- ing. and unite. An elastic catheter is first to be introduced. In the successful opera tion of this kind, which was actually done, the flap was held by four sutures; and small slips of adhesive plaster, and a bandage to support the scrotum, were employed. In the course of the treatment, pressure Was found necessary to prevent the occasional passage of urine through the wound. (A Cooper , Surgical Essays , Part 2 ,p. 221, fyc.) Mr. Earle met with a case, in which the integuments in the perineum, and above an inch of the canal of the urethra, had slough ed away in consequence of external violence. At the man’s entrance into St. Bartholomew’s Hospital, a large smooth cicatrix occupied the place of the urethra, no vestige of which remained in that part. The integuments on the right side had suffered less extensively than those on the left ; so that when the catheter was introduced, that portion of the instrument which pass.-d over the cicatrix could be about half covered, by drawing the skin and healed part from the right to wards the opposite side. The treatment was therefore begun by confining the knees to- gether over a pillow, a.m applying a kind of truss, which kept the skin constantly pressed towards the left side. While these measures were going on, the opportunity was taken of dilating the anterior portion of the urethra with bougies. Afterward the following ope- ration, which I had the pleasure of seeing, was performed ; a portion of the integuments was removed, about an inch and a half long, and one-third of an inch in width, on the left side of the cicatrix. The groove thus formed was intended for the reception of the edge ot the skin to be detached from ihe opposite side. An i. eision was then made across the perineum, above and below, so as to pare away the callous edges of the ure- thra. The skin was next dis-ected off from a portion of integument on the riglu side of the perineum, about an inch and - halt in length, and half an inch broad, leaving a smooth space of rather more than an inch be tween the cut surfaces. Ihe integuments on the right ^-ide were now dissected up, turned over a catheter, arid brought in contact with the opposite groove. The detached portion of cicatrix bled little during the operation, and before it could be applied to the groove, its edge bad so iivid an appearance, as to create an apprehension that it must perish. Two sutures were employed to assist in re- taining it in the desired position, and some straps of adhesive plaster and a bandage URINE, INCONTINENCE Ui > 00 ‘ completed the dressings. The day after the operation, it was evident that some urine had escaped by the side of the catheter; and on the third day, when the dressings were removed, it was found that the portion of flesh which had been deprived of skin, had sloughed, but that a sufficient quantity had united above and below to form a canal, open at one side, and large enough to in- clude the whole catheter. After the parts had healed, some urine could be made to passthrough the urethra, when pressure was applied to the left sicie of the remaining fis- tula. Various attempts were afterward made to excoriate its edges, and unite them, but without success. A second operation was therefore done in the summer of 1820, and integuments were now borrowed from the opposite side to that from which they had been taken in the first operation. A deep groove was. made on the right side, the surface was de- nuded of its cutis to some extent, a consi- derable portion of integument was then de- tached from the left side: and in order to obtain healthy skin (says Mr. Earle) I en- croached a little on the thigh, and laid bare the edge of the fascia lata. Instead of pass- ing any ligature through the detached por- tion, the "old quill-suture was employed, which was passed from the two outer cut surfaces. A pad of adhesive plaster was in- terposed between the ligatures and the llap of skin. 5 ’ The catheter was not left in the urethra, but introduced about three times in 24 hours. By this operation much more was gained, and about two-thirds of the de- ficient part of the canal were restored ; but still a small aperture remained at the upper part. This opening could not be closed by touching it with escharotics, and conse- quently, a third operation on a smaller scale was done, which so nearly completed the cure, as to leave only an orifice large enough to admit a bristle, and this opening subse- quently closed, arid the patient remained quite well in March 1821. (S ee Phil Trans, for 1821.) Here we see the same art by which new noses and under-lips are formed, extending itself to cases where it may be the means of extricating some individuals from a state in which life is hardly desirable, i'he surgeon of judgment, however, will never forget, that such an operation is only indicated where the fistula is large, the urethra lree from obstruction, and bougies ancl the ca- theter insufficient. URINE, INCONTINENC E OF. This complaint is quite the reverse of retention of urine ; for, as in the latter affection, the urine is continually flowing into the blad- der, without the patient having the power to expel it; so, in the former it Hows out, without the patient being able to retain it. According to Desault, children are parti- cularly liable to the disorder ; adults are less frequently afflicted with it ; and persons of advanced years appear to be still less liable to it. The last observation may seem an error to such practitioners as have met with numerous examples, where patients, advan- ced in years, were incapable of retaining their urine. The fact is, that the overflow of this fluid, or, in other words, its dribbling away through the urethra, in somecasesof re- tention, of which it is only a symptom, has been too commonly confounded with an incontinence of urine, though the cases are as different in their nature as possible, and require very opposite modes of treatment. In retentions , depending upon weakness and paralysis of the bladder , the involuntary drib- bling of the urine is generally only an effect of the other disease, and they prevail to- gether. The distended bladder reacts upon the urine, and forces some of it out of the urethra, until the resistance of the sphincter and of the urethra are precisely equal to the expelling power. Sometimes the urine even dribbles away incessantly, as is found to happen when the action of the bladder is entirely destroyed; for being then con- stantly full, it cannot hold any more of the urine descending to it through the ureters, unless as much be voided through the ure- thra as is received from the kidneys, and as unremittingly as the addition from the lat- ter organs continues to be made. Such case rather belongs to the article Urine , Reten- tion of than the present subject. v It is correctly remarked by Desault, that the causes of an incontinence of urine, strict- ly so called, are the very reverse of those of a retention. The latter case -happens whenever the action of the bladder is weak- ened, and the resistance in the urethra in- creased. On the contrary, an incontinence originates, either from the expelling power of the bladder being augmented, while the resistance in the urethra is not proportion- ately increased ; or from the resistance be- ing lessened, while the expelling force continues the same. On these principles, Desault thought it easy to explain why the disorder should be most common in chil dren ; and one reason which he gives for the circumstance is, that in childhood there is more irritability than at any other period of life. The expulsion of . the urine, he ob- serves, is entirely effected by muscular ac- tion while the resistance is merely owing to the sphincter vesicoe, the levatores ani, and perhaps to a few other inconsiderable fasciculi of muscular fibres ; for the different curvatures of the urethra, and the contrac- tile power of this tube itself, he thought, could make only a feeble resistance to the discharge of the urine. An incontinence happens in children, because the bladder contracts so suddenly and forcibly, that its contents are voided almost before these young subjects are aware of the occasion to make water, and without their being able to restrain the evacuation. There are also ma- ny children, who, from indolence, or care- lessness, do not make water immediately the first calls of nature invite them, and who afterward, beingurgently pressed, wet their clothes. In other young subjects, the sen- sation which makes the bladder contract and accompanies the expulsion of the urine. URINE, INCONTINENCE 01 oi>7 t* so slight, that the lu notion is performed without any formal act of the will, — with- out even exciting an impression sufficiently strong to disturb sleep. This is the case wit h such children as are troubled only with an incontinence of urine in the night-time. Increasing years, by diminishing the irrita- bility of tile bladder, and making man more attentive to his necessities, usually bring about a cure of the infirmity, w hich seldom continues till the patient has attained the adult state. It was not, however, the doctrine of De- sault, that no period of life, excepting child- hood, is subject to incontinence of urfne.. On the contrary, he admits, that other ages are subject to it but then it depends almost alw'ays upon a want of resistance to the es- cape of the urine. Thus, it may be occa- sioned by weakness, or paralysis of the sphincter vesica?, or levatores ani : some- times also by a forcible dilatation of the urethra, and loss of its elasticity, and, las Desault might have added) its muscular pow r er of contraction, since the microscopi- cal observations of Mr. Bauer, tend to con- firm the existence of muscular fibres on the outside of the membrane of the canal, though, as is elsew here mentioned, their ar- rangement and mode of action are now' re- presented to be quite different from w hat was formerly supposed. (See Urethra , Stric- tures of the.) A calculus, a fungus, or any other extra- neous body of an irregular shape, may lodge in the neck of the bladder, but not accu- rately filling it, may allow the urine to es- cape at the sides ; or there may even be in the calculhs grooves through which the urine may pass into the urethra. A violent contusion, or forcible distention of the sphincter, is often follow ed by an in- continence of urihe. F ormerly , the complaint used to be very common after the mode of lithotomy called the apparatus major, and it is even at present not an unusual conse- quence of the extraction of calculi from fe males, either by dilatation or division of the meatus urinarius, and neck of the bladder. Women, after difficult labours, and in "whom the child’s head has seriously contu- sed and weakened the neck of the bladder, are also subject to a species of incontinence of urine ; which, however, is in general ex- perienced only when they laugh, or make exertions. Incontinence of urine is stated by many writers to be an attendant on paisy and apoplexy. Here they mistake, what the French surgeons aptly call the “ retention d'urinc avec regorgeme?it ,” for an inconti nence. In such cases, the involuntary dis- charge of urine has been referred to paraly- sis of the sphincter of the bladder; but it is forgot, that the bladder itself aiso partici- pates in the paralytic affection ; for the sphincter now being a particular muscle, but only a fasciculus of fleshy fibres, form- ed, as Desault observes, by the junction of those which compose the inner layer of the muscular coat of the bladder, if can only be weakened in the same degree, and at the same time, as the rest of this organ. Be- sides, says Desault, it is proved, and all phy - siologists admit the fact, that the action of the bladder is absolutely necessary for the expulsion of the urine, and that when this organ cannot act, a retention alw ays ensues Although much less danger attends an in- continence than a retention of urine, the in- firmity is a serious affliction ; for as the pa- tient’s clothes are continually wet with a fluid that readily putrefies, the stench which he carries about w ? ith him, is offensive to himself, and every body who approaches him. In children, the disorder usually gets well of itself, as they grow up and acquire strength. When they wet their beds really from idleness and carelessness, moderate chastisement may be proper, inasmuch as the fear of correction w ill make them pay more attention to the earliest call to make make water. However, it has always been my own belief, that this doctrine is carried to an unjustifiable extent particularly in schools, and been a pretext for the most ab - surd kind of severity. Nor is it doubted by any man who understands the subject, that in almost all cases, the disorder is a true in- firmity, arising from the causes already in • dicated, and not from indolence ; the sup - posed crime taking place, in fact, w hen the child is asleep, and unconscious of what i? happening. If excessive irritability, and constitutional weakness, be the cause of incontinence of urine, and a very small quantity of urine forces the bladder to contract, the resist- ance of the urethra being involuntarily overcome, an endeavour should be made to lessen such irritability by the use of the warm, or cold bath, sea-batbing, tonics, chalybeates, good air &c. And in order to prevent the accident from taking place in the night-time, the child should not lake any drink for some time before being put to bed ; the bladder should be always emp- tied before sleep and if necessary, the child ought to be taken up in the night for the same purpose. li the infirmity arises from a want of ac- tion in the parts, causing the resistance in the urethra, tonics may be externally and internally employed. However, when tho disorder has been "of long standing, Desault found that they rarely succeeded. Palliative means are then the only re- source ; viz. instruments calculated either to compress the urethra, and intercept the passage of the urine, or to receive the fluid immediately it ss voided. The first of these plans is more difficult to accomplish in wo- men than men ; but if may be executed by means of an elastic hoop, which goes round the pelvis, and from the middle of which, in front, a curved elastic piece of steel de- scends, and terminates in a small compress, which is contrived to cover accurately the meatus urinarius. (See CUvvres Chir. uc De- sault par Bichat T 3, p. 95, ) Large blisters: applied over the os sacrum? URINE; RETENTION Oi &G8 Ixavc often cured an incontinence of urine, both when the complaint seemingly arose from excessive irritability of the bladder, and from paralysis and loss of tone in this organ and the parts, which naturally resist the expulsion of the urine from it, the case being in fact a retention “ par regorge me nt,” or, as one might call it in plain English, a retention, combined with incontinence of urine. (See Med. Obs. and Inq.) As, in some of these cases, the blisters removed also a paralysis of the lower extremities, they might have furnished a hint to the prac- tice of making issues for the relief of the palsy of the legs, connected with the dis- eased vertebrae URINE, RETENTION OF. It is ob- served by the experienced Mr. Hey, that a retention of urine in the bladder, when the natural efforts, are incapable of affording relief, is, in male subjects, a disease of great urgency and danger. Persons advanced in years, re more subject to this complaint, than she young or nii> idle-aged. Is is of- ten brought on by an incautious resistance to the calls of nature ; and if not speedily relieved, generally excites some degree of fever. The distinction, says Mr. Hev, which has sometimes been made between a suppression and retention of urine, is practical and judi- cious Tue. former most properly points out. a defect in the secretion of the kidneys ; the latter, an inability of expelling the urine when secreted. The retention of urine is an inability, whether total or partial, of expelling, by the natural efforts, the urine contained in the bladder. The characteristic symptom of Ibis disease, previous to the introduction of the catheter, is a distention of the bladder (to be perceived by an examination of the hypogastrium,) after the patient has dis- charged all the urine, which he is capable of expelling. As this complaint may subsist, when the flow of urine from the bladder is by no means totally suppressed, great caution is required to avoid mistakes. Violent efforts to make water are often excited at intervals, and during these strain ings, small quantities of urine are expelled. Such a case may be mistaken for strangury. At other times a morbid retention of urine subsists, when the palient can make water with a stream, and discharge a quantity equal to that which is commonly discharged by a person in health. Under this circum- stance, Mr. Hey has k own the pain in the hypogastrium, and distention of the bladder, continue till the patient was relieved by the catheter. And lastly, it sometimes happens, that when the bladder has offered its utmost distention, the urine runs off by the urethra, as ta>t as it is brought into the blad- der by the ureters. Mr. Hey has repeat- edly known this circumstance cause a seri- ous misapprehension of the true nature of the disease. In forming a correct judgment of all these cases, it is very necessary to recollect the important division of retentions of urine into the complete and incomplete forms; a distinction which will at once put the surgeon on his guard against a variety of errors. In every case of retention of urine which 'he iate Mr. Hey attended, the disease could be ascertained by an examination of the hy- pogastrium, taken in connexion with the other symptoms. The distended bladder torms there a hard and circumscribed tumour, giving pain to the patient when pressed with the hand. Some obscurity may arise upon the«exarnination of a very corpulent person ; but in all doubtful cases, the catheter should be introduced. Mr. Hey has not adverted to the swelling in the rectum, or vagina; nor to cases of contracted bladder, where, of course, the information, derived in ordinary instances from the tumour above the pubes, cannot be had; but in other respects, his observa- tions on the diagnosis are practical and correct. Mr Hey had seen only a few cases of is- churia reualis, or complete suppression of the secretion of urine. The disease proved faial in all his patients except one, in whom it was brought on by the effect of lead, taken into the body by working in a pottery. It subsisted three days, during a violent at- tack ot the colica pictonum, and was then removed, together with the original disease. Mr. Hey tound no difficulty in distinguish- ing this disorder, in any of the cases, from the ischuria vesicalis, though, for the satisfac- tion ot some ot his patients, he introduced the catheter. ( Practical Obs. in Surzery, p. 374 , fyc.) Re tention of urine, may be the effect of a great many different causes; as paralysis of the bladder; inflammation of its neck; the presence of foreign bodies in it ; pressure made on its cervix by the gravid uterus ; en largemerit of the prostate gland; strictures in the urethra; fee. . Every case of retention of urine demands prompt assistance, but where the disorder presents Itself in its complete form, the mis chief of delay is of the most serious nature ; for if the bladder remain preternaturally dis- tended, it not only loses its contractile pow- er, but is quickly attacked with inflammation and sloughing. At length some (joint of it bursts, and the urine is extravasated in the cellular membrane of the pelvis ; spreading behind the peritoneum as far up as the loins, and in other directions, into the perineum, scrotum, and the integuments of the penis, and upper part ot the tiiigbs. The common result then of the rupture of the bladder, and the effusion of its contents, is the speedy death » f the patient, from the effects of this irritating fluid upo all the parts with which it comes in contact, among which effects is inflammation ot the peritoneum und bowels. It appears also from '.he observations, both of Desault and Sir Evrard Home, that a com- plete retention ot urine alter a lime basilic effect of putting a mechanical stoppage to URINE, RETENTION OF u69 the further secretion of this fluid in the kid- neys ; a circumstance which sometimes has a principal share in producing death, parti- cularly where this event happens before the urine becomes extravasated. In all cases of retention of urine, the indi- cations are sufficiently manifest; viz. 1st, to adopt such treatment as seems best calcula- ted to procure a discharge of the urine through the natural passage, which object is performed, sometimes by means of fomenta- tions, the warm bath, bleeding, opium, and other medicines : sometimes bv the removal of mechanical obstacles to the flow of the urine ; hut more frequently b}' the use of the catheter, than any other means. When ell these plans fail, it then becomes necessary to puncture the bladder. 2dly. The second indication, or that which presents itself after the immediate dangers of the distention of the bladder, are thus guarded against, is to remove whatever dis- ease, or other circumstance, constitutes the still existing impediment to the natural ex- pulsion of the urine. With respect to the fit manner and time of employing the several means for fulfilling the above indications, and the selection which should be made of them, these are important considerations, which vary in dif- ferent cases, and actually cannot be under- stood, without due reference to the causes and circumstances of each individual case. A part of this subject belongs also to other parts of this work, to which, in order to avoid the necessity of repetition, I here refer. (See . Catheter ; Bladder , Puncture of; Prostate Gland, Diseases of; Urethra , Strictures of; *?c.) With respect to catheters, we shall find that some cases require the urine to be drawn off two or three times a day, and the instrument to be taken out after each evacua- tion ; while in other instances, it is prudent to keep the tube continually introduced. Here one general caution may be conveni- ently offered, which is, never to let a silver catheter remain in the passage more than a week or ten days, without taking it out and cleaning it ; for if this he not done, the instrument becomes coated with deposits from the urine, so as afterward not to admit of being withdrawn through the urethra, without great suffering and irritation. The eye in the beak is also apt to become com- pletely blocked up ; and sometimes the pres- sure which the catheter makes on the part of the urethra, corresponding to the root of the penis, in front of the scrotum, causes in this situation inflammation, followed by a slough as large as a crown piece, and an opening, formed by the loss of substance is left, which may even continue fistulous during the pa- tient’s life. These remarks particularly ap- ply to metalic catheters ; but such as are supposed to be made of elastic gum, espe- cially those ordinarily met with in the shops, are apt to spoil and become blocked up with mucus, if not taken out and cleaned, or changed, every five or six days. However, as I have mentioned in the article Prostate Vol. If. 73 Gland , Diseases of, Mr. Weiss lias succeeded in constructing elastic catheters, which will bear being retained more than a fortnight in the urethra, without becoming obstructed, besides having the advantage of always re- taining a due curve. 1. Of the Retention of Urine, to which per sons of advanced age are liable. -- This disor- der is so common in elderly persons, that it is generally allowed to be "one of the grie- vances to which their period of life is par- ticularly exposed. In them the bladder is less irritable than in younger subjects, and hence, it is not so soon stimulated by the presence of the urine. In fact, it is notun- til a painful sensation arises from the disten- tion of the coats of the bladder, that the pa- tient is aware of the occasion to discharge the urine. The bladder then contracts; but still would not be able to expel its contents, were it not for the powerful action of the abdominal muscles- Nor is the expulsion of the urine even now complete : since the bladder no longer retains the power of effa- cing the whole of its cavity. On the con- trary, alter each evacuation, some urine is still left undischarged, and already consti- tutes an incipient retention. The quantity daily augments, and at length, not more than half the fluid contained in the bladder is voided at each evacuation. According to Desault, the complaint par- ticularly attacks old subjects of a plethoric state of body, and of sedentary and studi- ous habits. It also especially afflicts those who, from carelessness or indolence, do not take time enough to expel the last drops of urine ; and others, who are accustomed to discharge their urine into a pot, as they lie in bed, instead of rising for the purpose. In these cases, the urethra and neighbour- ing parts seem to be free from every disease, capable of preventing the issue of the urine ; which has always come aw r ay freely, and in a full stream, although it could not be dis- charged with the same force, nor to the same distance, as formerly. At length, in- stead of describing an arch as it flows out, it falls down perpendicularly between the legs. Towards the close of the evacuation, the patient is also not sensible of the final contractile effort of the badder, of which he used to be conscious in his younger days. When he is about to make water, he is obliged to wait some time before the eva- cuation commences; and as the disorder increases, he cannot make water without considerable efforts ; the quantity of urine, voided each time, manifestly decreases ; the desire to empty the bladder becomes more and more frequent ; and lastly, the urine only comes away by drops, and an incontinence succeeds a retention. In this state, the patient’s sufferings are not very great. The tumour, formed by the bladder above the pubes, is indolent, and, if it be pressed upon with some force, a certain quantity of urine is discharged from the urethra. The retention of urine arising from old age is seldom complete the urine, after UKLNE, RETENTION 01 5.70' having filled anti distended the bladder, dribbles oat of the urethra, so that the pa- tient voids as much of this fluid in a given lime, as he does in a state of health. Nor is this species of retention of urine com- monly attended with very urgent symp- toms. It does not occasion, like complete intention, a suppression of the urinary se- cretion in the kidneys ; and as the urine escapes through the urethra, after the blad- der is distended to a certain degree, the disorder is less apt to produce a rupture of this organ, and dangerous extravasations of the urine. The swelling of the bladder then continues without any particular suf- fering, except a sense of weight about the pubes and perineum. These circumstances have often led to serious mistakes, and the disease has been set down as an abscess or dropsy. The indications are to evacuate the urine, and restore the tone of the bladder. When the retention is incipient, the proper action of the bladder will sometimes return after cold applications are made to the hypogas- tric region, or thighs, and the patient goes from a warm into a cool place. in order to make water. The patient must also be strictly careful to make water immediately the least incli- nation to do so is felt ; for, if this precau- tion be neglected, the bladder grows more and more inert ; the desire to make water subsides; and the retention, which at first consisted of only a few drops, very soon becomes complete. It would then be in vain, as Desault observes, to try the expe- dients above recommended. No stimulus will now make the bladder contract suffi- ciently to expel the whole of the urine, and the catheter is the only thing, by which this fluid can be discharged. This artificial mode of evacuation, however, only affords temporary relief; for as the bladder is slow in recovering its tone, a relapse would be inevitable, if the employment of the cathe- ter were not continued. Hence this instru- ment must either be left in the bladder, or in- troduced as often as the patient lias occa- ion to make water. When a skilful surgeon is constantly at hand, or when the patient knows how to pass the catheter himself, Desault thinks it better to introduce the in- strument only when the bladder is to be emptied, by which means the inconvenience arising from the continual presence of a fo- reign body, will be avoided. In this case, either a silver catheter, or an elastic gum one, may be used with equal advantage ; Hut if the instrument is to-be kept in tiie bladder, one made of elastic gum, and pro- vided with a curved stilet, is to be prefered. As in old subjects, the urethra is flaccid, a large catheter is generally found to enter more easily, than one of smaller diameter. As the treatment must be continued for a long while, and the bladder seldom perfectly regains its tone in old age, the patient should be instructed how to introduce the catheter himself, and he is to pass it whenever lie wants to make wafer. After a certain time. however, he may try if tie can empty ike bladder without this instrument. When he finds that he can expel the urine, he should certify himself by means of the catheter, that the last drops of this fluid are duly voided. Should they not be so, he must persevere in the use of the instrument. In this sort of retention of urine, it has been proposed to throw into the bladder as- tringent injections : Desault tried them ; but, he does not give a favourable report of the practice. Warm balsamic, diuretic medicines; cold bathing ; and liniments containing the tinc- tura lyttee ; have likewise been praised ; but according to Desault, these means frequent- ly prove hurtful to persons of advanced years, and are seldom useful. He restricted his own practice to the use of the catheter which, when skilfully employed, often re- stored the tone of the bladder, and when it failed, other means also were ineffectual. A blister over the sacrum may deserve a trial. Passing over (he cases of retention of urine, referred by Desault to the effects of intemperance with .women, and the immo- derate use of diuretic drinks ; cases which considerably resemble in their nature and treatment the retention, from the weakened state of the bladder in elderly persons, I proceed to another example of the disorder still more interesting to the practical sur- geon. 2. Retention of Urine from an Affection oj' the Nerves of the Bladder . — These nerves may be affected either at their origin, or in the course of their distribution. Injuries of the brain are seldom followed by a retention of urine, but the complaint often aceom panies those of the spinal marrow. A con cussion of this medullary substance, from blows, or falls upon the vertebral column ; the injury which it suffers in fractures and dislocations of the vertebra?, or from a vio- lent strain of the back ; its compression by blood, purulent matter, or other fluid effu- sed in the vertebral canal, and the effects, which a caries of the spine has upon it ; may all operate as so many causes of a re - tention of urine. This form of the com- plaint may also be the consequence of tu mours situated in the track of the nerves, which are distributed to the bladder. Whether the retention of urine, common in typhus fever, arises from an affection of the nerves of the bladder, or from the general debility extending itself to the expelling powers, may be a question ; but the liabili- ty of patients in fevers to this disorder should never be out of the practitioner’s recollection. When a retention of m ine arises from in- jury or disease of the spinal marrow, an in- sensibility and weakness of the lower ex- tremities are almost always concomitant symptoms. The patients suffer very little ; most of them are ignorant of their condi- tion ; and do not complain of any thing being wrong in the functions of the urinary organs. The surgeon, aware that a r©teu- URINE, RETENTION OF vioii of urine is common in these cases, shoulil examine, whether there is any inter- ruption of the evacuation, either by feeling the state of the abdomen just above the pubes, or by. introducing a catheter. As this species of retention of urine is only symptomatic, and not dependent upon any prev ious defect in the bladder, it is not in itself alarming; but with reference to its cause, it is exceedingly dangerous. Affec- tions of the spine, complicated with injury of the spinal marrow, are often fatal. By means of a catheter, it is always easy to re- lieve the inconveniences, arising from the bladder not contracting, and thus fulfil the only indication, which this sort of retention of urine presents ; viz. the evacuation of the urine. But this proceeding is merely palliative ; and the bladder will not recover ifs contractile power, until the causes of its x weakness are removed. The last then is the main object in the treatment, which must vary according to the nature and ex- tent of the disorder. The consideration in detail of all the means, which may be requisite for the relief of the different accidents and diseases of the spine, belongs to other parts of this work. (See Dislocations and Fractures of the Vertebrae; Vertebrae , Disease of.) In shocks and concussions of the spinal mar- row, Desault had a high opinion of the be- nefit resulting from cupping. This was done on, or near the part of the back, which had been struck, and the number of scarifica lions was proportioned to the strength of the patient. The plan was sometimes re- peated the same day, and for several days in succession ; and when the patient could not bear the loss of more blood, dry cupping was employed, which in this country, would be deemed less efficacious, than stimulating liniments or blisters. In diseases of the spine, Desault also preferred the moxa, to caustic issues. 3. Retention of Urine from Distention of the Bladder. — Desault thought that this form of the disorder might very properly be call- ed secondary , because it is invariably pre- ceded and produced by a 'primary retention. Of course, its remote causes are all those cir- cumstances, which may bring on the other forms of the complaint; but its immediate cause depends altogether upon the weakness and loss of irritability in the bladder, occa-* sioned by the immoderate distention of its coats. The disorder frequently occurs in persons, who from bashfulness, indolence, or intense occupation, neglect to make water, when they first have the desire ; or who cannot fora time empty the bladder, in consequence of some temporary obstruc- tion in the urethra Although the impedi- ment to the escape of the urine no longer exists, and the bladder is in other respects sound, yet as this organ has been weakened by the excessive distention of its coats, it cannot now contract sufficiently to oblite- rate the whole of its cavity, and expel the last portion of urine. The indication is simple : for there is not here, as in other retentions of urine, another disease to be remedied. The catheter, when left in the bladder, generally proves adequate to the restoration of the tone of this viscus. I do. not conceive, however, that English surgeons will place any confi- dence in warm diuretics which were com- mended by Desault, though they may join him in the approval of a tonic plan of treat- ment in general. When the urine flows from the catheter in a rapid stream, and is projected to some distance, and when it also passes out between the catheter and the urethra, it is a sign that the bladder has re- gained its power of contraction, and that it can empty itself, without the aid of the instrument. In this circumstance, the ca- theter is to be discontinued, and the patient; may gradually resume his usual mode of life. But When the urine passes through the catheter only in a slow stream, the catheter cannot be m>id aside, without the bladder becoming distended again, and losing whatever degree of tone it may have re- covered. , The time which the badder takes to re- gain its power of contracting, varies consi- derably in different cases. When the dis- ease is accidental and sudden, it frequently goes off in a few days. When it has come on in a slow manner, it usually lasts about six weeks. However, the cure is not to be despaired of, if the paralytic affection of the bladder should continue much longer. Sabatier says that he has seen patients wear a catheter upwards of ninety days, and yet ultimately get completely well. When there is reason for believing, that the urine will come away of itself, the use ot the catheter may be discontinued. When he makes water very slowly; when he is obliged to make frequent attempts: and when he feels a sense of weight about the neck of the bladder ; this organ lias not- completeiy recovered its tone, and the em- ployment of the catheter is still necessary. When the patient could make water tolera- bly well in the day, but not during.the rest of the 24 hours, Sabatier has often seen be- nefit arise from the catheter being worn only in the night-time. When three or four months elapse with- out amendment, Sabatier states bis convic- tion, that the tone of the bladder is lost for ever. In this unfortunate case, the patient should continue the flexible catheter, which he should be taught to introduce himself, as often as necessary. (See De la Mcdecine Operatoirc. T. 2.) Among the means deserving of trial, when the contractile power of the bladder does not return with the use of the catheter. I have to mention the tincture of cantha- rides ; blisters applied to the sacrum, and kept open with the savine ointment ; and cold washes to the hypogastric region. In all cases, where the incapacity of the bladder to contract, whether from weakness, or paralysis, is the cause of retention, arid where, though the bladder continues dis tended, a certain quantity of urine feFmde’d URINE. RETENTION OF. f> 72 daily, mistakes are particularly liable to be made. Thus, besides the chance of the disease being mistaken for an abscess, as Colot states was not uncommon in his time, other errors may take place. Sabatier was' consulted about a woman, who had been advised to repair to some distant mineral waters, with the view of dispersing a tumour, which remained after a difficult labour, and was supposed to be in the uterus itself. However, the swelling turned out to be only a retention of urine, as it disappeared as soon as the catheter was introduced. Here no suspicion had been entertained pf the real nature of the case, because the pa- tient had voided her urine in a voluntary manner, and in reasonable quantity, for the live, or six weeks, during which the swelling existed. In a thesis by Murray, a case is recorded, in which the swelling of the bladder was so considerable, that it was mistaken for drop- sy. The abdomen of a delicate woman began to enlarge, without any particular pain, and the cause was at first supposed to be pregnancy. This idea however, was re- moved by the enlargement increasing too rapidly, attended with a great deal of ana- sarca of the lower extremities, arms, and face. The patient was now considered to be dropsical ; and a surgeon was sent for to tap the abdomen. The fluctuation in the belly was quite evident. Fortunately, be- fore the operation was done, atrial of diu- retic medicines was determined upon ; and while this plan was going on, the patient was attacked with a total retention of urine for three days ; a symptom, which she had not previously suffered. It was now judged prudent to pass a catheter, before the tro- car was employed. Eighteen pints of urine were drawn olF, and the swelling of the abdo- men subsided. The next day, twelve more pints of urine were drawn off. The anasarca, which was entirely symptomatic, disappear- ed. The application of cold water re-esta- blished the tone of the bladder, so that when three pints of urine had been drawn oft’ by means of the catheter, the patient herself could spontaneously expel three or four others, with the aid of pressure on the hy- pogastric region. The retention of urine caused by weak- ness, or paralysis of the bladder, and the swelling above the pubes, may continue a long while, without any inconvenience, ex- cepting a sense of weight about the hypo- gastric region, and frequent inclination to make water Sabatier has known patients labour under the complaint more than six months. 4. Retention of Urine from Inflammation of the Bladder . — According to Desault, writers have ascribed different effects to an inflammation of the neck of the bladder, and to the same affection of the body of this viscus. They have in fact regarded the first case as a cause of retention ; and the tyst as a cause of incontinence of urine. An inflamed, highly sensible bladder, instead of being weakened, has been supposed to acquire an increase of energy, and to con- tract with greater vigour. But if there had not been retentions of urine, which could be referred to nothing but inflammation o the bladder, still analogy might have unde- ceived us ; for an inflamed muscle is never found disposed to contract, and if it be compelled to act, its action is always fee- ble. Plethoric, bilious subjects, are said to be particularly liable to this species of reten- tion. It is also frequently occasioned by the abuse of wine, or other spirituous liquors, heating diuretic drinks, or the external, or internal employment of lyttae. This form of the complaint makes its attack suddenly, and may be known by the frequent desire to make water ; the acute .pain, in the re- gion of the bladder; pain, which is increased by the efforts to make water, and which shoots up to the loins, and along the urethra to the end of the glans ; by the frequency and hardness of the pulse, and other symp- toms of fever ; by the aggravation of the pain, when the hypogastric region is press- ed ; by the easy passage of a catheter into the bladder; by the acute pain, which is excited by the instrument touching the in side of this organ ; and by the red, inflam matory colour of (he urine. In this case, the most prompt assistance is necessary. The urine, which is a source of additional irritation, should be drawn oft’. The catheter should be introduced with great gentleness, and merely far enough to let its eye pass beyond the neck of the blad- der. The inflammation itself is to be counter- acted by the most powerful antiphlogistic remedies, large and repeated venesections ; the application of leeches to the perineum and hypogastric regions; the warm bath glysters; fomentations on the abdomen; and cold mucilaginous beverages. When the inflammation extends to the other ab- dominal viscera, attended with hiccough, and vomiting, and continues beyond the sixth day, the patient’s life is in extreme danger. 5. Retention of Urine from Hernia of the Bladder . — An inability to discharge the urine is a symptom generally attending her- nia of the bladder. But the weakness of this organ is not always the sole cause of the infirmity ; for the urethra itself makes greater resistance than natural to the issue of the urine. As the neck of the bladder is drawn out of its right position by the por- tion of this organ which actually protrudes, the beginning of the urethra also undergoes an elongation, and a change of its curvature, by being pressed towards the symphysis of the pubes, and its diameter is likewise di- minished. ’fhe urine may also be detained in the pouch composing the hernia, in con sequence of the communication 'between this and the rest of the bladder being too small, or indirect, or perhaps from the her- nial portion not being compressed by r tho action of the abdominal muscle, or capable of any contraction itself. However, the URINE, RETENTION OF. oT4 rest of this organ, within the pelvis, can it- self rarely expel the last drops of the urine. Its complete contraction cannot be accom- plished without great difficulty ; and in the end it almost invariably follows, that the urine is retained both in the protruded and unprotruded portions. When a retention, arising from a hernia of the bladder, is complete, and occurs in both parts of this organ, there is, in addition to the symptoms common to other reten- tions produced by weakness of the bladder, a more or less considerable swelling in the situation of the hernia. Ihe tumour is un- attended with any change of the colour of the skin ; is not very tender; and it presents a feeling of fluctuation, sometimes obscure, sometimes very distinct. When the swell- ing is pressed upon, the desire to make wa- ter is excited, or increased, and occasionally a few. drops escape from the urethra. As soon as the urine has been drawn off with a catheter, and the patient is put in a pos- ture in which the protruded portion of the bladder is higher than the rest of this organ within the pelvis, the tumour subsides, and it is some time before it becomes large again. When the hernia is recent, and the pro- truded portion of the bladder small and re- ducible, the part ought to be returned and kept up with a truss. When the part is ad- herent and irreducible, the swelling ought to be emptied by pressure, and supported with a suspensory bandage. If the hernia could in this manner be made gradually to return into the abdominal ring again, a truss would afterward be requisite. Proposals have been made to endeavour to excite ad- hesive inflammation in the cavity of the protruded part of the bladder by compres- sion, gradually increased, and thus oblite- rate the pouch, in which the urine lodges. Although Desault thought the attempt cau- tiously made justifiable, be deemed the re- sult very uncertain. Were the retention of urine accompanied with a strangulated state of the protruded bladder, and the contents could not be pressed into the other part of this organ, a puncture of the swelling with a trocar has been advised. But if there were an entero- cele also present, as often happens, this ope- ration would be attended with risk of inju- ring the intestine. Hence, Desault prefer- red opening the tumour by a careful irtci- sion and he even approved of cuttingaway the protruded cyst, if the communication betwixt it and the rest of the bladder were obliterated. For additional observations, I refer to the 2d vol. of the First Lines of Surgery, Ed. 4. 6. i Retention of Urine , caused by displace- ments of the Viscera of the Pelvis. — The. dis- placements, here signified, are. a retrover- sion, prolapsus, and inversion of the uterus, and a prolapsus of the vagina, or rectum. When the intimate connexions of the blad- der with the uterus and vagina in the fe- male, and with the rectum in the male sub- ject. are considered, it is obvious, that the latter parts cannot be displaced, without drawing along with them the bladder; and that, in this state, whatever may be its con- tractile power, it cannot contract so per- fectly as to expel the whole of the urine. To this deficient action of the bladder is necessarily joined an increase of resistance on the part of the urethra ; for, the begin- ning of this canal being drawn by the blad- der, changes its accustomed direction, and such alteration cannot be made without the sides of the tube being pressed together. Thus the retroverted uterus draws the os tinc.se above tiie pubes, and the posterior part of the bladder is displaced,, which, in its turn, draws along with it the commence- ment of the urethra, pulls it upwards, and increases the curvature, which this canal de- scribes under the symphysis of the pubes, against which it is forcibly applied. In a prolapsus, or inversion of the womb, vagina, and rectum, the back part of the bladder, instead of being drawn upward and forward, is pulled downward and backward, and the curvature of the urethra is totally altered. Below the pubes the bladder form ; a convexity, and not a large concavity, as in the instance of a retroversion of the womb. This position of the parts should alw r ays be recollected in passing the cathe ter, as it shows what curvature and direc lion should be given to the instrument, in order to facilitate its introduction. These retentions of urine are not often followed by any very bad consequences. It is generally sufficient to rectify the wrong position of the bladder, and the commence - ment of the urethra, by the reduction of the displaced viscera, and a cure is then a mat- ter of course, unless the excessive disten- tion should have induced considerable weakness of the bladder, in which event, recourse must be had to the means previ- ously recommended for this state of the organ. The reduction of the viscera gene- rally forms the first indication, and the manner of accomplishing it is described un- der the head of Uterus. When the reduc- tion is not immediately practicable, or when it fails to remove at once the retention of urine, the catheter is to be used. Frequent- ly, when the urine has been d'-awm off, the reduction becomes more easy; but, some- times, the altered direction of the urethra renders the introduction of the catheter dif- ficult ; nor will the instrument pass, unless it be accommodated to the preternatural state of that canal. Thus, in the retrover- sion of the uterus, a catheter, very much curved, answers better than one nearly straight, like that commonly used for fe males. A curved catheter, says Desault, also an- swers in cases of prolapsus uteri, he. ; but with this difference, that, in a retroversion, the concavity of the instrument must be turned towards the pubes, but, in the pro- lapsus, towards the anus. Sometimes the catheter will not pass unless it be rotated, as it were, and sometimes, when a silver URINE, RETENTION OF. 754 catheter cannot in any manner be intro- duced, an elastic one will readily enter. Were every effort to reduce the viscera, and pass a catheter unavailing, and the ha- zard of the bladder giving way urgent, the surgeon would be called upon to let out the urine with a trocar. (See Bladder , Punc- ture of.) 7. Retention of Urine from Ike pressure of the Uterus , or Vagina, on the Keck of the Bladder. Besides the distention of the ute- rus and vagina in pregnancy and parturition (which cases I mean to pass over as be- longing more properly to midwifery,) there are other conditions of these organs which may give rise to a retention of urine. I bus It sometimes arises from the presence of various kinds of tumours, or collections of bu)od, or other fluid in the uterus, or ovary ; or the distention of the vagina with the menses, pessaries, &c. In such cases, the retention of urine being only symptomatic, the prognosis must de- pend upon the nature of the cause, of which the interruption of the urinary evacuation is only an effect. The latter complaint is here not very dangerous, because its incon- venience may be obviated by means of the catueter. But when the cause of the reten- tion of urine is easily removed, and the tone of the bladder is not impaired, even the catheter is not always necessary, as when the complaint is induced by a pessary, or collection of blood in the vagina. In other examples, in which the cause of the difficulty of making water cannot be imme- diately obviated, as in cases of tumours, the catheter must be employed. In scirrhous and cancerous diseases of the uterus, also, this instrument is the only means of re- lieving the retention of urine, as nature and art can do little for the removal of the cause. It ought to be known, however, that as these last diseases increase, an incontinence often succeeds to a retention of urine, in consequence of ulceration taking place be - tween the upper surface of the vagina and the lower part of the bl&dder. 8. Retention of Urine from pressure of the Rectum upon the Keck of the Bladder. Ab- scesses in the vicinity of this intestine, he- morrhoidal tumours, alvine concretions, and the scirrho-contracted state of the gut, he. may bring on a retention of the urine by pressure on the neck of the bladder. I he irritation, also, existing in these cases, may tend to produce the complaint by exciting a spasmodic contraction of the adjacent part of the urethra. Here the relief of the re- tention of the urine is to be effected by re- moving. or curing the other disorder, which operates as its cause, if this cannot be im- mediately accomplished, the catheter must be used, though, in several instances, it will be better to, avoid even the irritation of the catheter, and try the effects of bleeding, the warm bath, and opium, which will fre- quently enable the patient to make water. The last means, however, will not suffice, when the cause of the retention is likely to continue a long time 9. Retention of Urine from Foreign bodies in the Bladder. Without stopping to con- sider the uncommon kinds of retention pro- duced by carcinoma, fungous diseases, and hydatids in the bladder, let us pass on to the case, in which the urine is obstructed by a calculus a t the neck of the bladder. Here the patient, by altering his position, fre- quently changes the situation of the stone, and is immediately able to make water again. However, this expedient will only procure relief while the calculus is loose in the cavity of the bladder; for, after it has become fixed in the commencement of the urethra, it must either be pushed back with a catheter, taken hold of and brought out with the urethra-forceps used by Sir A Cooper, or extracted by a kind of operation resembling the apparatus minor. See Li- thotomy. Many instances of various kinds of worms in the bladder are upon record. On this subject, an interesting paper w 7 as published a few' years ago, by my friend Mr. Law- rence, who met with an example, in which an undescribed species of worms was abun- dantly voided from the bladder. “ The ori- gin of those animals (says Mr. Lawrence) w hich inhabit the internal parts of living bodies, is involved in much obscurity. Al- though the intestinal w orms appear manifest- ly , from their peculiar form, consistence, and organs, to be particularly designed for those situations in w hich they are found ; although they have generative organs, and no similar animals are know r n to exist out of living bodies, yet it has been generally conceived, thatthe germs, from which they spring, enter from the mouth. The production of hyda- tids in various parts of the body, cannot however, be accounted for on such a suppo- sition ; neither can w f e very easily conceive that ova should enter from without into the urinary organs.” The following facts, also stated by Goeze (as Mr Lawrence observes,) entirely overturn this opinion. Professor Brendel, of Gottingen, found ascarides in the rectum of an immature embryo. Blit menbach discovered tmniae in the intestinal canal of young dogs a few hours alter birth, he. ( Vermch einer Katurgeschichte der Ein - geiveidewurmer , p. 55.) The case, w 7 hich Mr. Lawrence has recorded, exhibits an un- questionable instance of peculiar and unde scribed worms, voided from the urinary passages. This gentleman says, that he knows cf no other case, in which a distinct species of w r orm has been clearly proved to come from the bladder. Most of the cases published were instances of common intes- tinal round worms, which sometimes perfo- rate the intestines and are discharged by abscesses, or get into the bladder, after the formation of adhesions betwixt this organ and the bowels. In other instances, coag ula of blood, mucus, or portions of the mu- cous coat of the bladder, have been mista- ken for worms ; and as Mr Lawrence fur- ther observes, some of the descriptions can apply only to larva* of insects. Two spe cjmens of this last sort, he has seen himself. URINE* RETE which were sent trorn the country as worms voided from the bladder. (See Medico- Chir. Trans, vol. 2, p. 382, fyc.) In whatever way these animals get into the bladder, a retention of urine may be produced, either when they are numerous, or when there is only one present, but large enough to obstruct the vesical orifice ot the urethra. In the very curious example rela- ted by Mr. Lawrence, the passage of the urine was obstructed, and the use of the ca- theter continually necessary. 'Jhe oil of turpentine was given internally, with some appearance of benefit at first ; but, it after- ward brought on febrile symptoms and ery- sipelas, and its exhibition could not be kept up. It was then injected into the bladder, with an equal part of water. This . rather accelerated the discharge of the worms ; but they came away at times, whether the injection was used or not, and as this means produced the erysipelatous indisposition again, it was left off. Olive oil was after- ward injected ; the irritation after it was less, and the fits of pain about the bladder less violent. It was calculated that at the time when Mr. Lawrence was writing the particulars of the case, from 800 to 1000 worms had been discharged. For a detail of the symptoms, and a particular descrip- tion of the worms themselves, we must re- fer to the above-mentioned publication. According to the observations of Desault, a retention of urine is frequently occasioned by coagula of biood in the bladder. The blood is said sometimes to come from the kidneys, sometimes from the bladder, and sometimes it even regurgitates from the ure- thra. While fluid, it may be expelled with the urine ; but, when coagulated, it is no longer capable of being discharged. It is the blood, w hich passes into the bladder, af- ter w r ounds, or the operation of lithotomy, that is most disposed to coagulate. If the clots were too large to pass through a cathe- ter, the best plan would be to inject into the bladder lukewarm water, for the purpose of loosening and dissolving them. A retention of urine, has sometimes arisen from the entrance of a piece of bougie into the bladder. Even whole bougies, which had not been properly secured, have been knownto glide into the cavity of that organ. As Desault observes, the urethra appears to possess a kind of antiperistaltic action, by which it tends to draw into the bladder whatever substances it includes ; for, says he, it is constantly noticed, that when these substances are once within the urethra, if they be not expelled by the urine, they al- ways advance towards the bladder ; a cir- cumstance which cannot be accounted for by their weight. The insinuation of these foreign bodies into the bladder is a serious occurrence both for the patient and surgeon. The for- mer cannot avoid the consequence which will sooner or later originate from the ex- traneous substance, except bv submitting to a dangerous and painful operation : the lat- ter will be accused of being the author of NT ION OF. S7 all the evil, and will find ii uitticull to excul pate himself. In order to obviate the neces sity of cutting into the bladder, in such cases, Desault,. proposed the use of small spring forceps, passed into the bladder through a cannula, hut, although the instrument seem- ed to answer on the dead subject, no instan ces of its doing so on living patients are on record. Were any instrument likely to succeed, 1 think it would be the urethra- forceps, shaped like a sound, employed by Sir A. Cooper for the extraction of small calcuii from the bladder. (See Lithotomy and Urinary Calculi. 10 . Retention of urine from Inflammation of the Urethra. In order to comprehend the mechanism of this case, it is neces sary to remember, that inflammation never exists, without swelling, and that every tumefaction of the lining of the urethra, must necessarily lessen its diameter. In- flammation of the urethra is most common- ly produced by the external application, or internal exhibition, of lyttae ; by gonorrhoea ; the unskilful use of the catheter; the em- ployment stimulating injections; bougies; & c. Together with the lessening of the ca- nal by the effect of swelling, there can also be no doubt, that, in many of these instan ces, a spasmodic contraction of the urethra and neck of the bladder also contributes to the retention of urine. Although Desault believed that inflamed parts, endued with a contractile power, were not disposed to con- tract in that state, yet, it should be recollect- ed, that even admitting this to be true, the whole length of the urethra is seldom in- flamed, and a part of it may therefore be af- fected with a spasmodic, action, without the theory espoused by Desault being at all im- plicated. The effects of opium, tobacco, and other antispasrnodics, often evinced in immediately relieving these kinds of reten- tion of urine, seem indeed to leave no doubt respecting the existence of a sort of spasm in the passage. Whatever may be the cause of inflammation of the urethra, the diagno- sis is free from all obscurity. Besides the general symptoms of inflammation, the pa- tient complains of a scalding sensation in the passage : he experiences a great deal of smarting, which is sometimes insupportable, when he makes water; the penis becomes ,in some degree swollen, and more tender; and a very little pressure on the urethra gives acute pain. In the mean time, the stream of urine becomes lessened ; and, at length, this fluid can only be voided in a very narrow current, or only by drops, and often not at all. The disorder is to be treated on antiphlo - gistic principles. Diluting, cooling, mucila- ginous, beverages ; venesection ; leeches to the perinauim ; the warm bath ; opium, particularly in the torm of clysters, and fo- mentations, are the means which usually give relief. When inflammation exists in the urethra, it is always desirable to avoid, as long as possible, the employment of ca- theters, which create irritation, and of course increase the cause of the retention, It is URINE, RETENTION Oi o7cl particularly, in cases of this description, ati<} in the retentions of urine, arising irom strictures, that Mr. Earle has suggested the use of tobacco in the form of clysters ; a method, deserving adoption when the means above enumerated are unavailing, and it is preferable to the catheter, because it does not cause any increase of irritation and in* flammatioq in the urethra. (See Med. Chir. Trans, vol. G,p- 82, fyc-) 11. Retention of Urine from Laceration of the Urethra, The urethra is sometime' rup- tured bv violent contusions on the perinaeum , and the rough and unskiuul use of bougies and catheters. The consequences usually are, an extravasation of urine in the cellul r mem- brane of the scrotum and penis ; a conside- rable dark-coloured swelling ot these parts, often followed by sloughing; and retention of urine. The treatment consists in in re- ducing an elastic gum catheter into the blad- der. with as little delay as possible, and keening it there until the breach in the canal j 3 repaired. At the «ame time, the evils threatened from the effusion of the urine are to be lessened as much as possible, by ma- king two or three free incisions in a depend- ing part of the swelling, and the employ- ment of fomentations, and antiphlogistic re- medies. 12. Retention of Urine from Tumours silu- ated in the Perinaeum, Scrotum, or Penis. A retention of urine has been known to arise from phlegmonous swellings and abscesses ; extravasations of blood; and urinary tu- mours and calculi formed in the perineum and scrotum ; also from the pressure of a sarco- cele ; hydrocele : a very large scrota! her- nia : an aneurism of the corpus cavernosum ; a ligature on the penis ; &c. The radical cure of all such retentions oi urine can only be accomplished by curing the disease, on which they are dependent. However, until the cause can be obviated, the urine must be drawn off with a catheter. Elastic gum-catheters usually enter more eas iiy than those made of silver, as by their flexibility they accommodate themselves bet- ter lo any deviation of the urethra from its ordinary direction. Desault particularly re- commended a catheter of middling size to be selected, and introduced, armed with its stilet, until is stops in the canal ; when he advised withdrawing the stilet for about an inch in order to leave the beak of the instill- ment quite free, so that it may follow the curve of the urethra. Then the tube and the stilet are to be pushed further into the canal, care being taken, however, to keep the stilet drawn back some distance irom the extremi- ty of the instrument. By these precautions, says Desault, the catheter may always be pot into the bladder. Should the introduc- tion prove neither painful nor difficult, De- sault thought it belter not to annoy the pa- tient by making him continually wear the instrument 13 Retention of Uyfne from Disease of the Prostate Gland. As a great deal lias been mu} concerning this case in aforegoing arti- cle, (see Prostate Gland,) 1 shall not here tie tain the reader long upon the subject. When the swelling of the prostate gland is of an inflammatory kind, the retention of f urine makes its appearance with the same kind of symptoms as attend inflammation about the neck of the bladder. Here similar treatment to that commonly adopted for the retention of urine produced in the latter ca-se, is indicated ; particularly bleeding, fomentations, the warm bath open- ing medicines, anodyne clysters, the tinctura ferri muriati, and in very obstinate urgent cases, an enema of lobacco. If these means fail, the surgeon may gently endeavour to introduce an elastic gum catheter. The symptoms of the retention of urine, caused by chronic enlargement of the pros- tate gland, and the reason of the impediment to the discharge of that fluid in such a case, are explained in another part of this work. (See p. 378, fyc. Vol. 2.) From the remarks there introduced, it appears, that when the regular evacuation of the urine begins to be impeded, the catheter becomes indispen- sable, though the surgeon will often be foiled in his endeavour to draw off the urine with it unless he be duly acquainted with the morbid changes produced in the parts. And, as Sabatier long ago very correctly- observed, the urine may not be discharged though the instrument enter a considerable way, either because its beak becomes en- tangled in the prostate gland, or between a swollen portion of ilvs gland and the neck of the bladder . and does not reach the urine. Hence Sabatier recommended the employ- ment of a catheter with a very long beak, which should also be bent considerably up- wards. When, however, all efforts to pass a catheter fail, the only resources are to force a passage with a conical catheter, as explained in Vol. 1, or to puncture the blad- der above the pubes. (See Bladder , Punc- ture of.) In this case, the operation should never be done through the perinamm or rectum, as the great size which the diseased prostate gland 'sometimes attains, would be an obstacle to making a puncture in either of these situations. Puncturing the bladder, however, is only a temporary means of re- lief; and until a catheter can be passed quite into the bladder, the cannula of the trocar should not be withdrawn. The objections to leaving the cannula in the wound any considerable time, are the irritation of the extraneous body ; the fear of calculous incrustations lorming both on the outside and inside of the cannula ; and the hazard of not being able to find the track into the bladder again, if the instru- ment were taken out for the purpose ol being cleaned. However, Sabatier approves of the practice under the foregoing circum- stances. And Colot adduces two instances in which it proved very serviceable Sa- batier also refers to another example of simi- lar success, related in the thesis by Murray. When Dr. Murray saw the patient, the can- nula had been worn more than a year, lhc patient was sixty years of age. and enjoyed URINE, RETENTION OF. 677 very good health. He was in the habit of taking a stopper out of the cannula every four hours. The wound had healed very well all round the tube, and was quite free from redness. ( Sabatier , Medecine Opkra- toire, T. 2, p. 140.) For further observa- tions, see Catheter and Prostate Gland. 14. Of the Retention of Urine produced hy Strictures in the Urethra. From the ac- count, which is given of strictures in ano- ther part of this Dictionary, (see Urethra , Strictures of,\ it appears that almost every stricture, bad as it may be, is capable of being rendered still worse, and the morbid part of the urethra more impervious by a spasmodic affection. Going out of a warm into a cold situation, drinking, and other kinds of intemperance, will often bring on an irritable state of the canal, attended with a spasmodic action of the strictured part, an increased difficulty of voiding the urine, and even a total retention of this fluid. The patient makes repeated efforts to re- lieve himself ; but hardly a drop of urine is discharged. In the meanwhile the bladder becomes filled, and ascends above the pubes ; the abdomen grows tense and pain- ful ; fever comes on; the countenance looks red ; the brain becomes affected ; and circumstances assume an extremely urgent appearance. In this case, antiphlogistic means should be adopted without delay. The patient ought to be bled, if nothing in his constitu- tion and age prohibit this evacuation, which it may even be proper to repeat. He should also be put into the warm bath, and fomen- tations should be continually applied to the hypogastric region. Slightly diuretic beve- rages may be prescribed, and leeches put on the perinaeum. The principal means, however, from which the greatest benefit may be expected, is a liberal dose of the tinctura opii, together with an anodyne glyster. This is also another example, for which Mr. Earle has particularly recom- mended the exhibition of tobacco in the form of a clyster ; and he has related a case in illustration of the efficacy of the plan. (See Medico- Chir. Trans. Vol. 6, p. 88.) The tinctura ferri muriati, which, ac- cording to Mr. Cline, has a specific effect in overcoming spasm of the urethra, seems also worthy of trial. Indeed it should al- ways be tried before tobacco, which being sometimes violent in its effects, ought per- haps to be the last resource in the way of medicines. When such measures fail in enabling the patient to empty his bladder, and this viscus is becoming more and more distended, an immediate attempt should be made to introduce a small flexible elastic gum-catheter through the stricture or stric- tures into the bladder, which object may be frequently accomplished, when due care, perseverance, and geritleness, are not ne- glected. Sometimes when a small flexible catheter cannot be introduced, a fine bougie admits of being passed into the bladder, and on Vol, II ' 73 being withdrawn, the urine follows, and is discharged. VVhen all the preceding plans prove un- availing, and the danger arising from the retention of urine continues to increase, either the stricture must be forced with the conical sound, an incision practised behind the obstruction, or the bladder punctured Ihe cannula of the trocar should then be left in the wound till the strictures are either cured, or at least till the urine re- sumes its natural course. 15. Retention of Urine from the Lodgment of Foreign Bodies in the Urethra. That such accident must obstruct the discharge of urine is too plain to heed any particular ex- planation. Calculi are the most common substances which bring on this kind of case ; but articles, introduced into the urethra from without, such as bougies, large pins, &c. are occasionally lodged in the passage ; and I opce extracted from a man’s urethra a long black pin, with which he had been examining the passage. The head of it was towards the perinajuin, and the point about two inches from the orifice of the glans. 1 passed the point through the lower surface of the urethra, and then taking hold of it, drew it further out, turned the head towards Ihe glans, from the orifice of which it was then easily removed. When substances like calculi lodge, oily injections are some- times tried with the view of rendering the passage more slippery ; and occasionally the dilatation of the canal with bougies or catheters, followed by a very forcible ex- pulsion of the urine, has answered. The ancients sometimes tried the effect of suc- tion. When the foreign body is closely embraced by the urethra, and it cannot be pushed forward with the fingers, Desault re- commends endeavouring to extract it with the forceps, invented for the purpose by Mr. Hunter, and wffiich are contained in a cannula ; or the urethra forceps, spoken of in the articles Lithotomy and Urinary Calculi might be employed. When, however, the foreign body is too large to be taken out its this manner, it must be extracted by an in- cision. If an elastic catheter be now kept in the urethra, so as to prevent the urine from coming into contact with the cut part, the wound will heal very well. Some time ago there was published a case of calculus in the urethra, attended with dysury, where almost instantaneous relief was obtained from the exhibition of a tobacco clyster. The patient soon felt a strong desire to void his urine; and “ upon making the attempt, a large calculus came rolling along the urethra, with complete relief of all his com- plaints.” (See Edinb. Med. and Surg. Jour- nal. Vol. 12, p. 373.) Fr. M. Colot, Trait6 de V Operation de la Taille ; avec dts Obs. sur la Formation de la Pierre , et les Suppressions de V Urine, fyc. 12 mo. Paris, 1727- Sabatier, De la M6de- cine OpAratoire, T. 2. C. B. Trye, Remarks on Morbid Retentions of Urine, 2d Ed. 90 the valves. Lastly, the idea is further sup- ported by the well-known fact of the fre- quent occurrence of varices during the state of pregnancy. But it has not been remem- bered, that the use of garters, for example, is extremely common ; yet varices of the legs are infinitely less frequent ; that very large varices are met with in persons, who have never employed anj r kind of ligatures, to which the origin of the complaint can be imputed ; that when the dilatation of the veins extends to the thighs and parietes of the abdomen, no causes of this description even admit of suspicion; that varicose veins are observable round several kinds of tu- mours, especially scirrhi, when there is no possibility of pointing out any mechanical obstruction to the circulation of the blood ; that varices sometimes make their appear- ance at the commencement of pregnancy, and long before the enlargement ot the womb can impede the free return of the blood through the veins in the pelvis ; that nothing is more unusual, than a varicose di- latation of the veins of the lower extremi- ties in consequence of swellings of the ab- dominal viscera ; and lastly, it has been for- gotten, that the knots of the dilated veins are far too numerous to admit of being as- cribed to the resistance of the valves. It cannot be denied, that pressure applied in the track of the vessels tends to promote their dilatation : but it can neither be con- sidered as tiie only cause, nor as the princi- pal one. The foregoing observations, made by Delpech, render it probable, that some unknown general cause is concerned in pro- ducing varices, the formation of which may also be facilitated by the impediments to the free return cf the blood, occasioned by certain attitudes, and particular articles of clothing. Mr. Hodgson conceives it probable, that, in some instances, the valves are ruptured in consequence of muscular exertions or ex- ternal violence, in which cases the pressure of the column of blood is the first cause of the dilatation of the veins. Sometimes also the disease appears to arise from preternatu- ral weakness in the coats of the veins, as, in those instances, in which, without any evident cause, it exists in various parts of the same person. ( Treatise on the Diseases of Arteries and Veins , p. 537.) Experience proves, says Delpech, that there is no ceriain mode of curing varices , strictly so called, which he thinks cannot be wondered at, since the nature and causes of the disease are completely unknown. The same source of knowledge, however, also proves, that the increase in the dilatation of varicose veins may be retarded, and that the oedematous swelling, attendant on the com- plaint, may be beneficially opposed by me- thodical and permanent compression. When the whole of a limb, affected with varices, is subjected to this last mode of treatment, the dilated veins subside, the circulation is more regularly performed, and the ccdema and pain '.ease There is not (says Delpech) any bet- ter method cf healing the solutions of con- tinuity in the soft parts, produced or kept up by the varicose state of the limb, and its consequences. But sometimes, as soon as the compression is discontinued, the varices make their appearance again, the pain recurs, the oedema returns, and the ulcers which were healed break out afresh. Inflammation of the integuments covering a varix, or varicose tumour, cannot invaria- bly be prevented by compression ; nor will this treatment always succeed even in remo- ving the intolerable pain which sometimes attends numerous clusters of varicose veins. In the first case, rest and relaxing applica tions will often succeed ; and in the second, the topical use of sedatives frequently gives relief. It has been proposed to puncture and empty varicose veins; but if a temporary emptiness and relaxation of these vessels were to remove the pain for a time, things would fall into the old state again in the course of a few days. If the plan were adopted, it would be necessary to make a free opening in the dilated vein, and extract the coagulum. The vessel would then need no ligature above and below the opening, for the slightest compression would afterward stop the bleeding, and the vessel be oblitera ted by the subsequent inflammation. We learn from Celsus, that the ancients were accustomed to remove varices by exci- sion, or destroy them with the oautery. ( De Re Medicd, lib. 7, cap . 3.) When the vein was much convoluted, extirpation with the knife was preferred ; but in other cases, the dilated vessel was exposed by an incision, and then cauterized. Petit, Boyer, and many British surgeons, have also sometimes cut out clusters of varicose veins. Delpech remarks, that the extirpation of tumours composed of numerous varices has been practised, either for the purpose of re moving the pain in the situation of the dis- ease, or other inconveniences. This opera- tion has been successfully performed ; but it appears not to have constantly had the effect of preventing the formation of new varices, and it has sometimes proved tedious, diffi- cult, and severely painful in its execution. In fact, an erroneous judgment must neces- sarily be formed of the extent of these swell- ings, when they are judged of only from the appearance which they present under the skin. Varices are not always confined to the superficial veins, and when they extend deeply, the operation must be ineffectual. The opinion of Delpech is, that it should never be undertaken, unless the disease be accompanied with perilous symptoms, or the patient nearly deprived of the use of his limb. It has been thought, that one of the esta- blished principles in the treatment of aneu- risms might be advantageously extended to the cure of varicose veins. By tying the principal venous trunk above the point to which the varicose affection reaches, it is said, that the course of the blood in the mor- bid vessels may be totally stopped ; the co- lumn of this fluid made to coagulate ; and VARICOSE VEINS. ' 1 j i .he consequent obliteration of the vessels themselves accomplished. The practice of tying veins for the cure of varices, appears to have been employed in the . days of Pare and Dionis, (Cours d' Ope- rations de Chirurgic, p. 610,) who have ac- curately described the operation of tying and dividing the vein between the two ligatures. Sir Everard Home has related many cases of varicose, veins in the lee, some of them accompanied with tedious ulcers, which, af- ter the vena saphena major had been tied, as it passes over the inside of the knee, were readily healed, and the dilatation of the veins of the leg relieved. This practice has sometimes answered ; but it bas also had its failures. Among other evils, an inflammation of the lied vein has been observed extending very far in (he vessel, and succeeded by great con- stitutional disorder, symptoms very anala- gous to those of typhus fever, and death. In some of these cases, previously to their ter- mination, abscesses form in the direction of the vessel below or above the ligature ; in others, such collections of matter are not observed. (See Travers on Wounds and Ligatures of Veins. Surgical Essays, Part 1,p. 216, ard Oldknoiv, in Edinb. .Med. and Surg. Journ. Vol. 5. R. Carmichael , in Trans, of the King's and Queen's College of Physi- cians, Vol. 2, p. 345, $-c.) Indeed, the dan- gers arising from an inflammation of the in- ternal coat of the veins are now generally acknowledged, and every endeavour should be made to avoid them. A case which hap- pened in Guy’s Hospital, in 1S16, fully proves them : the femoral vein happened to be pricked in an operation for aneurism, and a ligature was applied round the aperture. In- flammation of its internal coat took place, extending up into the vena cava, and the pa- tient is supposed to have died of the indis- position resulting from it. (See Travers's Surgical Essays, Part 1, p. 222.) Hence arises one of the most weighty ob- jections to the practice of tying the trunks of varicose veins, with the view of curing their morbid dilatation, and its effects upon the limb. As Mr. Brodie observes, it seems to be now established by the experience of mo- dern surgeons, that a mechanical injury, in- flicted on the trunk of one of (lie larger veins, is liable to be followed by inflamma- tion of its internal membrane, and a fever of a very serious nature ; and (he occasional occurrence of these symptoms, after the liga- ture, or even the simple division of the vena saphaena, has made surgeons less confident than formerly of the propriety of attempt- ing such operations for the relief of a vari- cose state of the branches of that vessel in the leg. Certain reflections, however, indu- ced Mr. Brodie to think, that the same ill effects would not follow a similar operation performed on the branches themselves. Where the whole of the veins of the leg are in a state of morbid dilatation, and the distress produced by the disease is not refer- red to any particular part, there seem to he no reasonable expectations of benelit, except from the uniform pressure of a well-applied bandage. But not unfrequehtly we find an ulcer which is irritable, and difficult to heal on account of its connexion with some Vari- cose vessels ; or without being accompanied by an ulcer, there is a varix in one part of the leg, painful, and perhaps liable to bleed, while the veins in other parts are nearly in a natural stale, or, at any rate, are not the source of particular uneasiness. In some of these cases, I formerly applied the caustic potash, so as to make a slough of the skin and veins beneath it ; but I found the relief which the patient experienced from the cure of the varix, to afford but an inadequate com pensation for the pain to which he was sub- jected by the use of the caustic, and the in convenience arising from the tedious healing of the ulcer, which remained after the sc paration of the slough. “ In other cases, 1 made an incision with a scalpel through the varix and skin over it. This destroyed the varix as completely as it was destroyed by the caustic, and I found it to be preferable to the use of the caustic, as the operation occasioned less pain, and as, in consequence of there being no loss of sub- stance, the wound was cicatrized in a much shorter space of time. 1 employed the ope- ration, Such as I have described it, with ad- vantage in several instances ; but some months ago I made an improvement in the method of performing it, by which it is much simplified; rendered less formidable, not only in appearance, but also in reality ; and followed by an equally certain, but more speedy cure. “ It is evident, (says Mr. Brodie,) that the extensive division of the skin over a varix can be attended with no advantage. On the con- trary, there must be a disadvantage in it, as a certain time will necessarily be required for the cicatrization of the external wound. The improvement to which 1 allude, consists in this : the varicose vessels are completely di- vided, while the skin over them is preserved entire, with the exception of a moderate punc- ture, which is necessary for the introduction of the instrument with which the incision of the veins is effected. Thus the wound of the internal parts is placed under the most favourable circumstances for being healed, and the patient avoids the more tedious pro- cess which is necessary for the cicatrization of a wound in the skin above. “ For this operation, I have generally em- ployed a narrow, sharp-pointed bistoury, slightly curved, with its cutting edge on the convex side. Having ascertained the pre- cise situation of the vein, cr cluster of veins, from which the distress of the patient appears principally to arise, I introduce the point of the bistoury through the skin on one side of the varix, and pas; it on between the skin and the vein, with one of the flat surfa- ces turned forwards, and the other backwards, until it reaches the opposite side. I then turn the cutting edge of the bistoury back- wards, and in withdrawing the instrument, the division of the varix 19 effected. The VEINS, DISEASES 01 592 patient experiences pain, which is occasion- ally severe, but subsides in the course of a short time. There is always hemorrhage, which would be often profuse if neglected, but which is readily stopped by a moderate pressure, made by means of a compress and bandage carefully applied.” Mr. Brodie particularly enjoins the ne- cessity of keeping the patient quietly in bed for four or five days after the ope ation, and removing the bandage and first dressings with the utmost care and gentleness. He also cautions surgeons not to make the in- cision more deep than absolutely necessary. Inflammation of the coats of the veins has not occurred in any of the cases, in which Mr. Brodie has adopted this method of treat- ment. This gentleman wishes it to be un- derstood, however, that he does not recom- mend the practice indiscriminately, but with a due attention to the circumstances of each individual case. “ The cases for which it is fitted, "are not those in which the veins of the leg generally are varicose, or in which the patient has little or no inconvenience from the complaint; but those in which there is considerable pain referred to a par- ticular varix ; or in which hemorrhage is liable to take place from the giving way of the dilated vessels ; or in which they occa- sion an irritable and obstinate varicose ul- cer.” (See Mdd. Chir. Trans. Vol. 7, p. 195, et seq ) On the subject of cutting through veins affected with varix, it is proper to observe, that even this plan has been known to bring on severe and fatal symptoms. Cases, con- firming this fact, are recorded in a valuable modern work, which should be in the hands of every practical surgeon. (See Hodgson's Treatise on the Diseases of Arteries and Veins, p. 555, et seq.) It is but justice to state, .however, that, in these examples, Mr. Bro- die’s manner of doing the operation was not adopted. On the contrary, his method, as far as l have yet heard, receives very gene- ral approbation. Some cases and observa- tions highly in favour of it, are detailed by Mr. Carmichael. (See Tram, of the King’s mid Queen’s College of Physicians, Vol. 2, p. 369, fyc.) Cases of spontaneous varix in the veins of the arm are rarely observed. When these vessels become varicose, it is almost always in consequence of a communication being formed, in the operation of venesection, between the brachial artery and one of the veins at the bend of the arm. The super- ficial veins in this situation then become more or less dilated, by the impulse of the .stream of arterial blood which is thrown into them. There is, however, a good deal of difference between these accidental va- rices, actually induced by a mechanical cause, and those which originate sponta- neously, or from causes not very clearly understood. The former never acquire the size which the latter often attain ; they never exceed a certain magnitude, whether pressure be employed or not ; they never form tumours composed of an assemblage of varicose veins ; they are never filled wuh tough coagula of blood ; their coats are never thickened, nor constitute the solid half-canal remarked in the other species of varices; the skin, which covers them, is not disposed to inflame and ulcerate ; they are not subject to occasional hemorrhage ; and the limb is not affected with any cede- matous swelling. ( Delpech , Traiti des Ma- ladies Chir. T. 3, p. 261.) These circum- stances render it evident, that here all sur- gical interference would be unnecessary. See Aneurism, where the aneurismal va- rix is described ; Cirsocele, where the varix of the spermatic chord is treated of; He- morrhoids, where the diseased and enlarged veins of the rectum are considered ; Vari- cocele, where those of the scrotum are no- ticed. VA'RIX. (from varius, unequal.) The term varices is applied to a kind of knotty, unequal, dark-coloured swelling. arising from a morbid dilatation of veins. (See Varicose Veins.) VEINS, DISEASES OF. To the obser- vations and references made in the prece- ding article ( Varicose Veins,) I here annex a few remarks on the principal diseases of the venous system, in order to render what has- been already stated, in other parts of the work, more complete. It is justly observed by Mr Hodgson, that 11 the veins are liable to all those morbid changes which are common to soft parts in general ; but the membranous lining of these vessels is peculiarly susceptible of inflam- mation. When a vein is wounded, the in- flammation, which is the effect of the injury, sometimes extends along the lining of the vessel into the principal venous trunks, and in some instances, even to the membrane which lines the cavities of the heart. This inflammation sometimes produces an effu- sion of coagulating lymph, by which the opposite sides of the vein are united, so as to obliterate the tube ; in this manner a great extent of the vessel is occasionally converted into a solid cord. In some in- stances, the secretion of pus into the cavity of the vessel is the consequence of inflam- mation of the membranous lining of veins : under these circumstances, the matter is either mixed with the circulating blood, or, the inflammation having produced rfdhcsion of the sides of the vessel at certain intervals, boundaries are formed to the collection ot pus, which in this manner form a chain ot abscesses in the course of the vessel. “ When the inflammation of veins is not very extensive, its symptoms are the same as those of local inflammation in general : but when the inflammation extends into the principal venous trunks, and pus is secreted into the vessel, it is accompanied with a high degree of constitutional irritation, and with symptoms which bear a striking re- semblance to those of typhus fever. (See Hodgson’s Treatise on the Diseases of Arteries and Veins, p. 611, 512.) Besides the example of inflammation ot femoral and other large veins, brought on VENEREAL DISEASE. o9J by u ligature round a small aperture, acci- dentally made in the femoral vein, in the operation for popliteal aneurism, as men- tioned in a foregoing article, (Varicose Veins.) Mr. Travers reports another case, in which a fatal inflammation of the femoral and ex- ternal iliac veins, with marks of diffused in- flammation up to the right auricle, was ap- parently caused by the application of a liga- ture to the mouth of the femoral vein, after an amputation. (P. 227.) And the same catastrophe would appear to be occasionally the result of venous inflammation after am- putation, even where the femoral vein is not tied. (See Carmichael, in Trans, of King's and Queen's College of Physicians, Val. 2, p. 365.) In short, Mr. Travers’s ob- servations, as well as those of Mr. Hodgson and Mr. Carmichael, tend to prove, “ that the inflammation of the interior tunic of a vein sometimes follows a puncture, some- times a division, a ligature encircling the tube, or including only a part of it, or arises spontaneously from an inflamed surface, of which the vein forms a part.” (P. 238.) Mr. Carmichael relates an instance, in which the appearances after death seem to evince that the patient died subsequently to an op- eration .for femoral aneurism, of inflamma- tion and suppuration within the femoral vein, and extending both down the saphena, and upwards through the common iliac vein. The femoral vein had been pricked in the operation, but not tied. (Trans, of the King's and Queen's College of Physicians, Ireland, Vol. 2. p. 350, fyc.) In order to avoid the danger of wounding the femoral vein, above the edge of the sartorius, Mr. Carmichael recommends “ introducing the needle on the pubal side of the artery (P. 357) a direction which should have been considered in the article .Aneurism. Inflammation frequently produces a thick- ening of the coats of the veins, as well as adhesion of their sides, and obliteration of their cavities. Indeed, in some instances, these vessels have been found to resemble arteries in the thickness of their coats, and in retaining a circular form when cut across. ( Hodgson , up. cit. p. 513.) Ulceration sometimes extends to the coats of veins, and, by exposing their cavities, gives rise to hemorrhage. In certain exam- ples, it commences in the membranous li- ning, and destroys the other coats. In ge- neral, however, the adhesive inflammation precedes the ulcerative, and by obliterating the cavities of these vessels, prevents the oc- currence of hemorrhage. When sphacela- tion takes place in the vicinity of veins, their cavities, like, those of arteries under similar circumstances, are filled with exten- sive plugs of coaguium, which prevent he- morrhage upon the separation of the mor- tified part. Veins are sometimes Ruptured, without any previous morbid alteration in their structure, and the accident may be induced by muscular exertions, external violence, the sudden effects of the cold bath, &,c. Although a deposition of calcareous mat- R Vot,. If, 75 ter almost invariably takes place in the ar- teries of persons advanced in life, it is an extremely rare occurrence -in the coats of veins Loose calculi have been found in the ca- vities of veins ; and tumours sometimes grow from their lining. In a case of scir- rhous pylorus, Mr. Hodgson found a turnout*) larger than a hazel nut, growing from the lining of the splenic vein,’ and resembling in its appearance and consistence the disease which existed at the pylorus. (P. 524.) The venous, like the arterial system, ap- pears to be capable of carrying on a colla- teral circulation, when any part of it is im- pervious. Even after the obliteration of the vena cava inferior, the blood lias been known to be conveyed with facility loibe heart through the lumbar veins and vena azygos. In the case recorded by Dr. Baillie, ( Trans, for the Improvement of Medical and Chir. Knowledge, Vol. 1, p. 127.) it is. re- markable, that the vena cava inferior was obliterated at the point where the venae cavee hepaticee opened Into it, so that not only the blood from the lower extremities, but also that from the liver, must have pass- ed through collateral channels to the heart. Want oi : room having prevented me from introducing further observations on the dis- eases of veins, I must refer to the following works for additional , information. J. Hun- ter, in Trans, for the Improvement of Med. and Chir. Knowledge, Vol. J. Abernethy's Works. J. Hodgson on the Diseases of Arte- ries and Veins. Longuet , Dis. sur 1' Inflam- mation des Veins, Paris, 1815. B. Tracers, in Surgical Essays, Part 1, 8ro. Lond. 1818. F. A. B. Puch el t , Das Venensystem in Seinen Krankhaflen Verhaltnissen. Sro. Leipz 1818. R. Carmichael, in Trans, of the Association of Fellows, fyc. of the King's and Queen's Col- lege of Physicians in Ireland, Vol. 2, Svo. Dublin, ISIS. VENEREAL DISEASE. (Lues Venerea Morbus Gallicus. Syphilis.) About the year 1494, or 1495, the venereal disease is said to have made its first appearance in Europe. Some writers believe, that it originally broke out at the siege of Naples ; but most of them suppose that, as Columbus returned from his first expedition to the West Indies about the above period, his followers brought the disorder with them from the new to the old world. Other authors, however, among whom is Mr. B. Bell, maintain the opinion, that the venereal disease was well known upon the old continent, arid that it pre- vailed among the Jews, Greeks, and Ro- mans, and their descendants, long before the discovery of America. Although many considerations lead me to reject the common history of syphilis as fabulous, I mean that account which refers its origin to America, or the French array in Italy, it does not appear to me. that any utility would be likely to result from agita- ting this question in modern tunes, because, if it be true, as the most candiAwid intelli- gent surgeons of the present rally acknowledge, that they cannot precisely A V IbNEltEAL DISEASE b94 define what the venereal disease is, nor al- ways point out the exact circumstances, in which it differs from some other anomalous complaints, even when the cases are before their eyes, how can such discrimination be attempted from a mere review of old de- scriptions, unaccompanied with the advan- tage of letting the reader judge from the living patients themselves P But, as far as the nature of the venereal disease has been unravelled, and it is allowable to judge from such comparisons, I may be permitted to remark, that, in degree of severity, the acuteness of symptoms, rapidity of propa- gation, and extent and quickness of fatality, no forms of disease, now ever conjectured to be venereal, bear the least resemblance to the destructive malady, with which the army before Naples, at the close of the fif- teenth century, was afflicted : nor will any ignorance of the uses of mercury, as will be presently noticed, explain differences so strongly marked. The venereal disease is supposed to arise from a specific morbid poison, w hich, when applied to the human body, has the power of propagating or multiplying itself, and is capable of acting both locally and constitu- tionally. Mr. Hunter was of opinion, that the ef- fects produced by the foison arise from its peculiar or specific irritation, joined with the aptness of the living principle to be irri- tated by such a cause, and the parts so irri- tated acting accordingly. Hence, he con- sidered. that the venereal virus irritated the living parts in a manner peculiar to itself, and produced an inflammation, peculiar to that irritation, froiri which a matter is pro- duced, peculiar to the inflammation. The venereal poison is capable of aflat: t- ing the human body in two different ways : locally, that is, in those parts only to which it is first applied ; and constitutionally, that is, in consequence oi its absorption. In whatever manner the venereal disease was first produced, it began, says Mr. Hun- ter, in the human race, as no other animal seems capable of being affected by it. He conceives also, that the parts of generation were those first affected ; for, if the disease had taken place on any other part, it would not have gone further than tne person in whom it first arose. On the contrary, if the disease, in the first instance ot its for- mation, be presumed to have attacked the parts of generation, where the only natural connexion takes place, between one human being and another, except that between the mother arid child, it was in the most favour- able situation for being propagated ; and Mr. Hunter infers, also, that the first effects of the 'disease must have been local, in con- sequence ol ijie fact, now well established, that none of the constitutional effects are communicable to other persons, ihat is to say, infectious^ Thus, the Atfinberless cases of the vene- real diseasaJpicting generation after gene- ration, ijyjdjBbservable in all the known parts effme world, are. supposed to be originally derived from the amours oi some' unfortunate individual, in whom the poison was first formpd, from causes beyond the reach of human investigation. But, that any statement of this kind is more valuable than unsupported conjecture, is a proposition to which my mind is not prepared to assent, particularly when it is considered, that sores on the genitals, giving rise to such constitu- tional symptoms as puzzle the most discern- ing practitioners of the present enlightened days of medical science, are often of a very diversified character, so as hardly to admit, of reference to one common origin. And, as l have already hinted, every modern spe - culation, about the first origin of the distem- per, promises but little instruction orsuccess, because the question relates to a disease, the diagnosis of which is still very unsettled, and the complete definition of which has hitherto baffled men of the greatest genius and experience. According to Mr. Hunter, the venereal poison is commonly in the form of pus, or some other secretion. In most cases, it ex cites an inflammation, which (to use the same author's language,) is attended with a specific mode of action, different from an other actions attending inflammation, and accounting for the specific quality in the matter. The formation of matter, though a general;, is not a constant attendant on this disease , for inflammation, produced by the venereal poison, sometimes does not terminate in suppuration. But, if Mr. Hunter’s senti- ments are correct, it is the matter produced, whether with or without inflammation, which alone contains the poison. Hence a person, having the venereal irritation in any form, not attended with a discharge, cannot communicate the disease to another. In proof of this doctrine, he states, that though married men often contract the disease, and continue to cohabit with their wives, even for weeks, yet, in the whole of his practice, he never once found, that the complaint w as communicated under such circumstances, except when connexion had been continu- ed after the appearance of the discharge. The late Mr. Hey, of Leeds, however, gave it as his opinion, that a man might com municate lues venerea, after all the symp- toms of the disease had been removed, and he was apparently in perfect health. (Sec I, fed. Chir. Trans. Vol. 7, p. 547.) This senti- ment is not only repugnant to the authority of Mr. Hunter, but to common observation and all sound reasoning. The very case, which Mr. Hey adduced, in proof of the occurrence, is decidedly inadequate to the intended purpose, in consequence oi the im- possibility of trusting to the accounts which patients, under circumstances involving their honour, are apt to give ot themselves. In the case, recited by Mr Hey, the gentleman might have had some venereal affection, at the period of, or subsequently to, his mar- riage ; and yet his feelings, and a sense of the disgrace of infecting a virtuous woman, might compel him to conceal the real truth VENEREAL DISEASE. > wm his surgeon. Again, it is to be remem- bered, that the lady herself might have de- viated from the path of chastity, and ex- posed herself to infection ; and, if she had done so, she would neither have informed her husband, nor Mr. Hey. I confess, that it is at all times painful to suspect the vera- city of individuals, whose situations in life are respectable ; but, whenever an occur- rence takes place, decidedly contrary to the evidence of general experience, every pos- sibility is to be recollected, in order to avoid the necessity of admitting doctrines not founded upon truth. Mr. Hey, with much more reason, joins in the belief of the possibility of the venereal disease being communicated to the fetus in utero, though in wbat manner the infection is transmitted is a question not yet elucida- ted. An universal desquamation of the cuticle ; a hoarse squeaking voice ; copper- coioured blotches ; a scaly eruption upon the chin ; and an unnatural redness of the anus ; are the common symptoms which Mr. Hey sets down as proofs of syphilis in very young infants. As these complaints yield to snjalllffoses of the submuriate of mercury, or the hVdrargyrus cum creta, arid either the nurse or parent has had some venereal or syphiloid disease at no very distant period, the cases are often regarded as decided spe- cimens of one of these disorders. The venereal poison would appear to be very irregular in its effects, different persons being variously affected by it and hence, probably, one cause of a great deal of the uncertainly, yet prevailing about its distin- guishing characters. Thus, as Mr. Hunter mentions, two men sometimes have connex- ion with the same woman ; both catch the disease ; but one may have very severe, the other exceedingly mild, symptoms. He knew of an instance, in which one man gave the disease to different women, some of whom had it with great severity, while the others suffered but slightly. On the same point, 1 find an interesting statement, made by Dr. Hennen, in his Report of Ob- servations on Syphilis in the Military Hospi- tals in Scotland : — “ We have had (says he) frequent opportunities of remarking two or more sores, of different kinds, existing at the same time : an irregularly-shaped diffused sore ; an elevated sore, covered with a light coloured slough, as if a bit of shamoy leather had been stuck on by some tenacious sub- stance ; a groove, or streak along the glans, as if made by a scraping instrument, filled with purulent matter; and the true and per- fect chancre, according to Mr. Hunter’s difi- nition ; or the true syphilitic ulcer, according to Mr. Carmichael. This last has, in some cases, occupied the glans ; in some, the prepuce ; while the sores of another des- cription have been on the same part close beside it, or on another part at a distance. Three of these cases I particularly selected for examination and public demonstration, at the Castle Hospital ; in one, the Hunte- rian chancre vva-s on the glans, and a sore, without any hardness on the prepuce ; in an- other, it was on the prepace, and a simple ulcer on the glans in the third, a most per iectspecimen of Hunterian chancre occupied the internal prepuce, close to the corona glandis ; and, at about half an inch from it, nearer the frftnum, but farther from the glans, was an elevated ulcer. In all these cases, the Hunterian chancre healed (without mercury) several days before the others. “ Soldiers (says Dr. Hennen) arc gregari- ous in their amours, arid we have frequently several men at the same time in hospital, in- fected by the same woman, with whom they have had connexion in very rapid succession : some of them have had one kind of sore, some another, and some both. (Principles of Mili- tary Surgery, Ed. 2, p. 52o.) But, if there facts, which agree with my own observa- tions, lie rather adverse to the theory of a plurality of venereal poisons (See Carmi- chaels Essays on the Venereal Disease, fyc.,) they still leave difficulties, which cannot be entirely solved by reference to peculiarities of constitution, and different states of the health, because no explanation, on this prin- ciple, would account for a man having, at the same time, upon the penis, two or til rte different kinds of ulcers, apparently excitod by one cause. Neither* will any difference of texture afford the needed explanation, though the utmost latitude be given to the doctrine, that the appearance and progress of sores are considerably modified by the na- ture of the parts. It is only necessary to consider the above passage from Dr. Hen- nen’s work, to perceive that the particular texture, whether prepuce, skin, glans, or corona glandis, does not always communi- cate to sores one invariable character, even when they arise, as the evidence would dis- pose one to suppose, as nearly as possible under the same circumstances, and from the same source of infection. But, though in such examples, no data, with which 1 am acquainted, lead to any safe inference, respecting the exact cause of the diversity, of effect, produced in different persons, and even on different parts of the same individual, by one kind of virus, not a doubt can be entertained, that generally climate and constitution have vast influence over the venereal disease. In all warm countries, the disorder, as far as regards the natives, and those who have been long set- tled there, is not ofily much milder in its symptoms, but much more easy of cure. In the West Indies, the Brazils, &c. it has fora long period of time been very commonly cured by means of sarsaparilla, guaiacum, mezereon, &c. without a grain of mercury It is alleged, however, that this mildness of syphilitic complaints, and their facility of cure, in warm climates, do not extend to strangers, recently arrived there, who are said even to suffer more from the virulence of the disease, than in their native climate. In Portugal, during the fate war, the dread- ful ravages of the venereal disease among the British soldiers, and its comparatively milder phenomena among the inhabitants of the country, were particularly noticed. “In the British army, (says Mr. Fergusson) it is probable, that more men have sustained the VENEREAL DISEASE mos* piduneholy of all mutilations, during tfie four years that it lias been in Portugal, through this disease, than the registers of all 1 lie hospitals in England could produce for the lust century ; while venereal ulceration has not only been more intractable to the operation of mercury, than under similar circumstances at home; hut the constitution, while strongly under the influence of the lemedy, has become affected with the se- condary symptoms in a proportion that could not have been expected.' With the natives, on the contrary, the disease is very mild ; curable, for the most part, by topical Treatment alone, or wearing itself out when received into the constitution, after running a certain course, not always a very destruc- tive one, without the use of any adequate mercurial remedy, &ic. The bulk of the people, and of all the military at the hospitals, even though a general order has been given out, enjoining the use of mercury, cure themselves, or get cured, by other means. I have now been upwards of two years at the head of their hospital department, and I can declare, that it never occurred to me, among all the venereal patients, whom in that time I have seen pass through the hos- pitals, to meet a single one under the in- fluence of mercury, excepting those cases, wherein I myself have personally superin- tended its administration. They go out cured by topical remedies gdone : and I have lived long enough among them to ascertain, that their return to hospital under such cir- cumstances for secondary symptoms, is far from being an universal, or even a frequent occurrence. ( Fergusson , in Med. and Chir. Trans. VoL 4,p. 1,2.) The inference, at which Mr. Fergusson arrives, is, that in Portngal, the disease is exhausted, and has lost much of its virulence, in the some manner as the natural small pox, unresisted by inoculation appears to have changed, in the same country, into a very mild disease, which does well under any mode of treatment. u Yet (says Mr. Fergusson) 1 have no doubt, that were this mild disease, or the mildest that was ever produced from the improved inoculation of England, communi- cated to a tribe of Indians, or to a plantation of negroes, or any other class of people, who had never before known the small pox, it would desolate, with all the fury of pesti- lence, destroying wherever it? could find victims, and never ceasing until it had des- troyed the whole.” And, on the same prin- < spies, Mr. Fergusson attempts to explain the severe effects of the inoculation of the e xhausted syphilitic virus of Portugal into the constitution of the British, or other stanger, ;snd the impossibility of curing the disease by the same treatment, which answers for the natives themselves. (Med. Chir. Trans. Vol. 4, p. 7, 10.) On the other hand, Mr. Guthrie does not admit, that the disease which the*-troops contracted in Portugal was more violent, than the same complaint in England ; <>r rather he admits the fact, but gives a different explanation of it from that erf Mr. Fergusson : and refers the severe effect of the disease upon the soldiers in Portugal to the operation of the climate upon their northern constitutions, and to their irregularity and intemperance, vices, to which the natives are not addicted. (See Med. Chir. Trans. Vol. 8, p. 563.) It has been a contested question, whether the venereal disease and gonorrhoea arise from the same poison ? Mr. Hunter ac- knowledges,. that the opinion, of their ori- ginating from two distinct poisons, seems to have some foundation, when the difference in the symptoms, and method of cure, is considered. But he asserts, that if this question be taken up upon other grounds, and experiments be made, the result of which can be safely depended upon, this no- tion will be found to be erroneous. As the arguments of Mr. Hunter, in support of the doctrine that both diseases are produced by the same virus, are noticed in the article Gonorrhoea , I shall not here repeat them. On the other hand, Mr. Bell relates some experiments, from which the conclusion is made, that the poisops of the venereal dis- ease, and gonorrhoea, are entirely different and distinct. Matter was taken upon the point of a probe, from a chancre on (he glans penis, before any application was made to it, and completely introduced into the urethra. For the first eight days, the gentleman who made this experiment, felt no kind of unea- siness ; but about this period, he was attack - ed with pain in making Water. On dilating the urethra, as much as possible, nearly the whole of a large chancre was discovered, and in a few days a bubo formed in each groin. No discharge took place from the urethra, during the whole course of the disease ; but another chancre was soon per- ceived in the opposite side of the urethra, and red precipitate was applied to it, as well as to the other, by means of a probe pre- viously moistened for the purpose. Mercu- rial ointment was at the same time rubbed ou the outside of each thigh, by which a profuse salivation was excited. The buboes, which till then, had continued to increase, became stationary, and at last, disappeared entirely ; the chancres became clean, and by a due continuance of mercury, a com- plete cure was at last obtained. If this case, and another to which 1 shall present- ly advert, could be entirely depended upon,, they would tend to disprove the part of Mr. Hunter’s theory, accounting for the different effect's of the same poison by its application in the case of chancre to a non-secreting surface, covered with cuticle, and in that of gonorrhoea to. a secreting mucous membrane. However this may be, l have never seen a chancre within the urethra. The next experiment was made with the matter of gonorrhoea, a portion of which was introduced between the prepuce and glans, and allowed to remain there without being disturbed. In the course of the second day, a slight degree of inflammation was produced, succeeded by a discharge of matter, which in the course of two or three days, disappeared. VENEREAL DISEASE. The same experiment was repeated ; but no chancre ever ensued from it. Two medical students were anxious to ascertain the point in question ; and with this view, they made the following experi- ments, at a time, when neither of them had ever laboured under either gonorrhoea, or syphilis, aud both in these and in the pre- ceding experiments, the matter of infection was taken from patients who had never made use of mercury. A small dossil of lint, soaked in the mat- ter of gonorrhoea, was by each of them in- serted between the prepuce and the glans, and allowed to remain on the same spot for the space of twenty-four hours. From this it was expected, that chancres would be pro duced ; but in one, a very severe degree of inflammation ensued over the whole glans and pra>putium, giving all the appearance of what is usually termed, gonorrhoea, spuria. A considerable quantity of fetid matter was discharged from the surface of the inflamed parts, and for several days, there was rea- son to fear, that an operation would be ne- cessary for the removal of a paraphymosis. By the use of saturnine poultices, laxatives., and low diet, however, the inflammation abated, the discharge ceased, no chancre took place, and the case got entirely well. In the other gentleman, says Mr. B Bell, the external inflammation was slight, but in consequence of the matter finding access to the urethra, he was attacked on the second day with a severe gonorrhoea, with which lie was troubled for more than a year. The next experiment was made by the friend of the latter student ; he inserted the matter of gonorrhcea, with a lancet, beneath the skin of the prasputium, and likewise, into the substance of the glans ; but although this was repeated three different times, no chancres ensued. A slight degree of inflam- mation was excited : but it soon disappear- ed, without any thing being done for it. His last experiment was attended with more serious consequences. The matter of a chancre was inserted on the point of a probe to the depth of a quarter of an inch, or more in the urethra. No syifiptorns of go- norrhoea ensued ; but in the course of five, or six days, a painful inflammatory chancre was perceived on the spot, to which the matter was applied. To this succeeded a bubo, which ended in suppuration, notwith- standing the immediate application of mer- cury; and the sore, that was produced, proved both painful and tedious. Ulcers were at last perceived in the throat, nor was a cure obtained, till a very large quantity of mercury bad been given, and the patient kept in close confinement for thirteen weeks. (On Gonorrhoea Virulenta and Lues Venerea, Vol. 1, Edit. 2 ,p. 43S, fyc.) Mr. Evans, it appears, has also several times inoculated with the matter of gonorrhoea, but in every case, it failed to produce any effect. (On Ulceration of the Genital Organs, p. 81, 8to. Lond. 1819.) Some other facts 6n record however, ♦end rather to support. Mr. Hunter’s infer- enco, if any conclusion can bo ventured upon without the aid of the most minute details. Thus, Vigarous mentions an in- stance, in which six young Frenchmen had connexion with the same woman, one after the other. The first and fourth in the order of connexion, had chancres and buboes, the second and third gonorrbma, the fifth chan- cre, and the sixth bubo. (CEuvres de Chir. Practique Montp. 1812, p. 8.) And Dr. Hennen, who refers to this case, mentions a similar one, in which the first person esca- ped, the second had true chancres and eleva- ted sores, and the third gonorrhoea. The connexion took place within an hour. (Mi- litary Surgery, Edit. 7. p 52G.) These facts would indeed be much more interesting, if the disease, with which the women were affected, had been ascertained, and one could securely calculate upon the men not having exposed themselves, within a given time, to any other sources of infection. In short, without a perfect history and descrip tion of cases of this kind, from their begin Ring to their end, no light is thrown by them on the question about the venereal and gonorrhoeal poisons. Nor does Dr. Hennen quote them with this view ; but for the purpose of exemplifying the variety of effects, produced on different individuals apparently , by the same infection, though the same consideration, which prevents any certain inference from such observations, in regard to the identity of the venereal and gonorrhoeal poisons, seems also to interfere with the other conclusion. In the experi- ments, detailed both by Hunter and B Bell, there is also one point assumed by both parties, though it is far from being deter- mined ; viz. that the matter discharged from the urethra is always of one kind, in respect to its infectious principle whatever this may be, and that the secretion from every chan- cre contains one, and only one species of infectious matter. From the candid and very practiqal work of Mr Evans, it would appear, that some ulcerations on the penis, such as would usually be called chancres, though they have of late years been some- times named elevated ulcers, arise from an altered secretion, without any breach of sur- face , or discernible disease in the female or- gans. The same gentleman was also fre- quently present at the examinations of the public women in Valenciennes, and always surprised at the small portion of disease to be found among them : “ At one which 1 attended, (says he,) no less than 200 women of the lowest description, and of course, the most frequented by soldiers, were exa- mined, and not one case of disease was found among them ; nevertheless the mili- tary hospitals had, and continued to have, their usual number of venereal cases (ulcer- ations.) le At an inspection I have since attended, where 100 women -were examined, only two were found with ulcerations : 1 noticed several with increased secretions, and one with purulent discharge, but these were taken no notice of by the attending VENEREAL DISEASE. .m geons, as they uiu not come sufEicietitly under the head of virulent gonorrhoea. “ That the two women, above mentioned as having ulcers, infected the whole of the men diseased in garrison, during the prece- ding fifteen days, no one can for a moment admit even as likely ; but if it be allowed, that an altered secretion be sufficient for the production of this disease, (the ulcus eleva- tum) we shall at once have an explanation of how it happened, that the military hos- pitals continued to have their usual number of venereal cases, he.” ( Evans on Ulcera- tions of the Genital Organs, p. 72, 73, fyc.) From the investigations of the same author, the ulcus elevatum is the most frequent of nil the sores met with on the genitals, and besides being excited by diseased secretions, and gonorrhoeal matter, is capable of being transferred bp inoculation, and even of ori- ginating spontaneously. (P. 67 — SI, fyc.) Lagneau admits, that gonorrhoea may not always proceed from the same poison as the venereal disease ; but he believes, that in the greater number of instances, the virus is of the same quality. He is led to this opinion by the consideration of several women having been infected by the same man with both complaints, and of the two diseases having been communicated to several men who had cohabited with one- woman, and as is presumed with her alone, at least, inasmuch as may relate to the pos- sibility of any other infection weakening the conclusion attempted to be drawn from the case; a point, which has only been as- sumed, and by no means ascertained. How- ever, be this and other similar narrations true, or not, in every particular, I agree with Mr. Guthrie in believing, that the evidence, adduced on the point under consideration, justifies the opinion, “ that ulcers will arise on the penis from the matter of gonorrhoea ; that gonorrhoea will, in itsturn, be caused by the matter of these same ulcers, and that both occur in consequence of promiscuous, or uncleanly intercourse. That many of the ulcers , produced in this manner, will occasion- ally assume every character of chancre, and cannot be distinguished from it, I am perfect- ly satisfied of from repeated observation ; but I am equally certain, that a gonorrhoea in men, with the worst appearances and symptoms, can, and often does, arise from irritating causes common to parts free from any specific disease, or poison, is not distin- guishable from one that has arisen from promiscuous intercourse, and that both complaints are curable in the same way, and without mercury.” On the question, whether gonorrhoea, or the ulcers resulting from the matter of gonorrhoea, can produce constitutional symptoms, Mr. Guthrie be- lieves, that they generally do not, although he does not affirm, that they cannot under particular circumstances of constitution ; and he is further of opinion, that if such symptoms ever really arise, they become serious only in consequence of the exhibi- tion of mercury. fSee Med. C-iiir. Trans. Vol. 8, p. 564 From what has been already observed, it must be evident, that one of the greatest obstacles to our arrival at a satisfactory knowledge of the nature of lues venerea, is the fact, that under this denomination, many various diseases are comprised and con- founded, and the particular distinctions of each of which are not yet sufficiently made out, to enable surgeons to form a well- founded, and practical classification of them, satisfactory to every impartial observer, and agreeing with general experience. But though such progress has not yet been made, the attention of modern practitioners, and especially that of Mr.'Carmichael, has been directed to the subject. In fact, not- withstanding some mysterious circumstan ces in particular syphilitic cases may not admit of complete and satisfactory explana lion by the doctrine of a plurality of poisons, no intelligent surgeons, I believe, now sup- pose that the diseases, frequently Communi- cated by sexual intercourse, always proceed 1 from one peculiar poison. As Mr. Rose has observed, long before syphilis is supposed to have commenced its career in the world, some of these diseases were frequently met with, and Mr. Pearson thinks, that, in addi- tion to those formerly known, new forms of disease have occasionally arisen, “ which are succeeded by a regular series of symp- toms nearly resembling the progress of lues venerea.” ( Obs . on the Effects of various articles of the Materia Medica in the Cure of Lues Venerea, 2 d Ed. Introd. p, 53; and Rose in Med. Chir. Trans. Vol. 8, p. 418b Mr. Hunter also, in the seventh chapter of his Treatise on the Venereal Disease, speaks of many examples of new-formed diseases, arising from peculiar poisons, quite different he supposes, from every other virus pre- viously known, or judged of b)' its effects. But, though Mr. Rose appears to join in the belief of a plurality of poisons, he is very far from considering it settled, how far the variety in the symptoms of venereal cases is to be attributed to different poisons, or how far the symptoms of the same poison may be modified, and altered by constitu- tion, climate, 4 and habits' of life. He re- marks, that we seldom have an opportunity of tracing different cases to the same source of infection, and of comparing their pro- gress with each other. (Vol. cit.p. 419.) And, 1 may add, that as far as observations of this nature have been made, and can be trusted, they rathertend to prove, as al read} noticed in the foregoing columns, that dif rerent individuals, when infected nearly at the same time, and by the same woman, arc very far from having any uniformity in their complaints ; some having one kind of sore : some another; and others claps, he. And the tenor of the remarks, made likewise by Mr. Evans, as far as he has yet entered into the subject, lead equally to ihe conclusion, that one primary complaint, when it pro- duces another, does not always occasion one resembling itself. Thus, the ulcus elevatum on the penis, though capable of being communicated by inoculation, appear- V ENEivEAL DISEASE od sometimes 10 be the effect of one kind of infection, sometimes of another, and sometimes even to have a spontaneous ori- gin. Who shall unravel all these intricacies, 1 know not, whether he bring to his assist- ance plurality of poisons, or states of the parts and constitution, climate, neglect, wrong treatment, or any other circumstance, which can possibly be conceived to have influence over the appearances, progress, and consequences of the disease? Nay, it would appear from some of the curious and perplexing histories mentioned in the pre- ceding pages, that one kind of primary com- plaint in an individual may impart to other persons primary complaints of a different nature, so that even the hope of elucidating parts of this abstruse subject, by adverting to a plurality of infections, and a vigilant observation of their characteristic effects, meets with discouragement almost at its very birth ; and though the doctrine of se- veral kinds of poisons being concerned in the production of syphilis and syphiloid diseases still maintains its ground, an abso- lute proof of its correctness can hardly be said to have been yet afforded ; nor, indeed,- could it be obtained, unless the inoculation of healthy individuals with the matter of the different forms of disease were justifia- ble for the elucidation of the question. And, as this is not the case, I think, with Mr. Carmichael, that it might be a benefit to society, if criminals were sometimes per- mitted to commute a heavier punishment by submitting to such experiments, without which the inquiry into the reality, number, nature, and etfects of the morbid poisons under consideration, can perhaps never be brought 4o a satisfactory termination. “ I am perfectly aware (says Mr. Carmichael,) how much the state of the human constitu tion will modify local diseases, and am willing to attribute to a certain extent, the great variety of appearances, we witness daily in venereal complaints, to this cause alone. But, we observe that many of those primary ulcers evince, from their very com- mencement, such peculiar and distinct cha- racters, that it would be quite an absurdity to believe, that the virus is always the same, and the variety of characters dependant alone upon constitution. Thus nothing can be more opposite, from the commencement, than the common chancre, with its hardened base, like a piece of cartilage under the skin, and the sloughing ulcer. The first is slow and chronic ; the latter begins with a morti-, lied spot, extends by alternate sloughing and phagedenic ulceration, and makes more pro- gress in tnree days, than the- former in as many Weeks. “ The phagedenic ulcer is equally distinct from chancre, as it does not evince, at any period, a hardened base, but gradually creeps from one part to another of the penis, leav- ing those parts to heal, which, in thp first in- stance, it attacked ; so that, when the disease has existed for some months, the gltuis is seen to exhibit its entire Surface furrowed over with ulcerations and cicatrices. byb “ There is a raised ulcer, also, with elcva ted edges, approaching the nature ot the phagedenic ulcer, yet, whose characters are sufficiently distinct to be considered as a separate species. But, the most common venereal primary ulceration presents such various appearances in different individuals, that, until a more exact knowledge is ob- tained ; it is better described by its negative, than its positive qualities, and it may be de- signated an ulcer without induration, raised edges, or phagedenic surface. “ If (continues Mr. Carmichael) the plura- lity of venereal poisons is supported by the variety of primary ulcers, it is equally so by the multiplicity of constitutional eruptions. A primary ulcer, which was not phagedenic, or sloughing, at first, may afterward, like any other ulcer, become so by irritation, neglect, or inflammation. But 1 do not conceive, that we have grounds for suppo- sing, that the state of the constitution can so modify morbid poisons, as to cause the same virus to produce in one person the chronic scaly lepra, and psoriasis, and to assume in another a decided pustular form, each pus- tule spreading rapidly into a deep ulcer. (On the Symptoms and Specific Distinctions of Vtncrtal Diseases, p.6, fyc. 8 vo. Lund. 1818.) The same gentleman, in his Essays on this subject, published some years previously to the above date, gives his reasons for believ- ing that certain primary appearances are fol- lowed by a corresponding train of constitu- tional symptoms. 1st. That the syphilitic chancre gives rise to scaly eruptions, lepra, and psoriasis, an excavated ulcer of the ton- sils, and pains and nodes of the bones. 2dly. That the ulcer, without induration, raised edges, or phagedenic surface, gonorrhoea virulenta, and excoriation of the glans and prepuce, are followed by a papular eruption, which ends in desquamation, pains in the joints resembling those of rheumatism, sore- ness of the fauces, and frequently swelling of the lymphatic glands of the neck ; but without any nodes of tue bones 3dly. That the ulcer, with elevated edges, in the few instances in which it was traced by Mr Carmichael to its constitutional symptoms, was followed by a pustular eruption, which terminated in mild ulcers, pains in the joints, and ulcers in the throat, but no appearance of nodes. 4;hly. That the phagedenic and sloughing ulcers are generally attended with constitutional symptoms of peculiar obsti nacy and malignancy : \oz. pustular spots and tubercles, which form ulcers, generally spreading with a phagedenic edge, and heai- ine from the centre Extensive ulceration of the fauces, particularly of the back of the pharynx, obstinate pains of the knees, and other joints, w hile nodes are frequently pre- sent, and the bones of the nose are occasion - ally affected. (See. Carmichael's Essays and his 0$s. on the Symptoms, i \-c, of Ven. Dis- eases, p. 9.) The observations of other modern writers seem generally to coincide with those of Mr. Carmichael, respecting the great variety of character in primary venereal sores, and VENEREAL DISEASE. GGU partly also with regard to iiie hypothesis of (here being various kinds of poisons, or in- fectious matter, But, on some other great questions, immediately connected with these points, little similarity of opinion pre- vails between him and other gentlemen, who have laudably arid impartially entered into the disquisition. And, in the first place, without adverting again to certain state- ments, already premised, which render it probable, that differences of the virus, or, at all events, differences in the forms of the primary complaints in the contaminating individuals, would nbt always explain the reason of the diversified appearances and nature ot the primary forms of disease in the contaminated, I shall Iav.’before the reader other evidence, having an immediate rela- tion to Mr. Carmichael’s sentiment, that each kind of primary veneral sore is follow- ed by a peculiar and corresponding train of constitutional symptoms. In the cases re- cited by Mr. Rose, “ most of the papular eruptions followed ulcers, which were not very deep, and which healed without much difficulty. Several of them had a thickened, but not a particular indurated margin. This corresponds with the observations cf Mr. Carmichael , — I could not , howtvcr, discover any decidedly uniform character in such sores ; and the 16th case I should have considered as a well-marked instance of chancre.” (Med. Chir. Trans. Vol. 8, p. 399.) In another place, it is staled, that the appear- ances of sores can seldom be relied on in parts of such vascular structure, and in the midst of sebaceous glands. (P. 419.) With respect to the phagedenic ulcer, Mr. Rose expresses his belief, that it is rarely followed by secondary symptoms, though he inclines to the opinion, that it arises from the application of some morbific matter, ac- knowledging, however, (he great difficulty of deciding, “ whether the great degree of erethismus, excited by the local affection, should be attributed to any peculiarity in that matter, or is owing to the peculiar state of the constitution.” (Med. Chir. Trans. Vol. 8, p. 372.) And he then refers to the ease, reported by Mr. Fergusson, where • the infection was communicated by an opera dancer at Lisbon, apparently in per- fect health, who continued on the stage for several months afterward, occasionally in fecting others, without any thing extraordi- nary, as far as he could learn, in the nature of the symptoms.” (Op. cit. Vol.4,p. IE) And, on the same subject, Mr. Guthrie does not think, ‘‘ that Mr. Carmichael’s opinion, as to the secondary symptoms, peculiar to the phagedenic and sloughing ulcer, re- ceives any support from what occurred to the troops in Portugal ; because it did not appear, that either of (hem, following sexual intercourse, were dependent on the cause which produced the ulcer. Where many men have had intercourse with the same woman (and with no others ?) they have not all had the same complaint, although one of th ? ulcers, so originating, has become pha- gedenic. or sloughed ; neither has the same woman herself suffered from this distemper indeed, the nature of an ulcer of either kind must, after a short time, effectually prevent any intercourse, and we often find, that their peculiar characters only appear after the ulcer has existed for several days. I firmly believe also, that in the greater number of cases of sloughing ulcer, where mercury is not given, no secondary symptoms would ap- pear : and, in thost cases in which they did appear, I apprehend, they would be equally dependent on the state of the constitution, as to the mode of cure, arid their destructive characters. In other words, my observations lead me to conclude, that these ulcers do not depend upon a specific poison, but on the stale of the constitution , under particular excite- ment, and that, when, secondary symptoms occur , they are not dependent on the stale of the ulcer ; although 1 am ready to admit, that in a constitution where an ulcer will readily become phagedenic, the secondary symp- toms, when they occur, may be different to a certain extent from those that follow more simple ulcers, in a healthier habit of body.” (Guthrie in Med. Chir. Trans. Vol. 8 ,p. 664.) My observations lead me to believe, with Mr. Guthrie, that primary sloughing ulcers do not depend upon any peculiar poison, and I am also disposed to join him in the opinion, that when hurtful local treatment is out of the question, they are chiefly owing to the stale of the constitution. According to my experience, all kinds of ulcers on the genitals may, from particularity of constitu- tion, impairment of health, and sometimes from the pernicious effects of the immode- rate and indiscriminate einploymentof mer- cury, assume in their progress a sloughing disposition, and even have it from their very commencement. Mr. Rose mentions a case in which a healthy young man was affected with a sloughing sore on the penis, in consequence of a suspicious connexion. It was not attended with any constitutional disturbance, and yielded readily to mercury. The same patient, twice afterward, at a very considerable interval, had a fresh infection, and the sores each time had precisely the same character as the first. This, says Mr Rose, is no uncommon occurrence, and it is not probable that the sloughing and appear- ance of the sores arose from the peculiarity of the poison. (Med. Chir. Trans. Vol. S, p. 420.) And another intelligent and expe- rienced surgeon, who has particularly at- tended to this investigation, declares his conviction, that many varieties of sore, independently of the sloughy chancre, men - tioned by Mr. Carmichael, lead to constitu- tional symptoms, differing in no respect from those he has described, and admitting' of the same mode of cure.” Nor does he believe, with Mr. Carmichael, that only one particu lar species of sore is capable of producing the true secondary symptoms of lues. ( J Baud, on Syphilis, p. 51 ) From these observations, I think we may safely infer, that with respect to the slough- ing ulcer, it neither arises from the applica- tion of any one specific poison to the part. venereal disease col nor is it connected with any regular train secondary symptoms. Dr. Hennen assures us, that he has fre- quently had occasion to observe, that erup- tions of the same nature and character have succeeded to the foul, indurated, excavated ulcer, and to the simple excoriation. “ In fifteen cases of eruptions, unaccompanied by any other symptoms, which succeeded the Hunterian sore, six were tubercular, five exanthematous, two pustular, one tu- bercular and scaly, and one tubercular and vesicular. “In four cases following the same sore, but in which the eruptions were complica- ted with sore throat, two were tubercular, one was tubercular and scaly, and one was tubercular and axanthematous. “ In twelve cases following the non Hunte- rian sore, and in which eruptions were the only symptoms, six were pustular, three were exanthematous, and one was tubercu- lar and scaly. 11 In seven cases where the eruption was accompanied with sore throat, three were exanthematous, two were tubercular, one was papular, scaly, and tubercular,” and one was pustular and tubercular. Dr. Hen- nen also recites an instance in which a Hunterian chancre was, at the distance of ten weeks, succeeded by a papular eruption , which, in the course of a month, was remo- ved by low diet, purgatives, and the decoc- tion of sarsaparilla. In two months after- ward, an eruption of a similar nature ap- peared without any fresh infection. This Was treated with mercury, which was admi- nistered five weeks, so as to excite a mode- rate salivation. Under this treatment the eruption faded, having, during its progress, assumed the appearance of vesicles and pus- tules, and at length falling off in amber- coloured scales , with livid bases. Notwith- standing this mercurial course, the patient was h third time admitted, ten weeks after- ward, (without any intervening primary affection) with a pustular eruption, which was finally cured without mercury, and the pustules falling off in squamulae. In ano- ther month, without any fresh infection, he Was a fourth time taken into hospital, with a very thickly dispersed pustular erup- tion, somewhat different from the former, the pustules being more nunaerous, smaller, and acuminated. They yielded to non- mercurial treatment. During all these attacks, there was apththous sore throat, and occasional flying pains in the joints. The inference drawn from this case is, that even a full and judiciously conducted mer- curial course does not prevent the reappear- ance of venereal eruptions, and that they assume at different times different charac- ters, notwithstanding the interruption they receive in their natural progress by the use of that remedy. (On Military Surgery, Ed. 2, p. 528—530.) After these accounts, I can have no hesitation in coming to another conclusion, which is, that, with the excep- tion of the partial confirmation of Mr. Car- michael’s doctrine by Mr. Rose, as far as Vol. IE. “ 75 of relates to the frequency of papular erup tions after superficial primary ulcers, the regular connexion of particular forms of secondary symptoms with any given de- scriptions of primary sores, is so far from being supported by the testimony of other observers, that one kind of primary ulcer may lead, in the same patient, to eruptions of several different sorts, either existing to- gether on various parts of the body, or breaking out in succession ; and no regular connexion can be traced between any one species of primary sore, and any determi- nate class of secondary symptoms. These truths, 1 believe, must be admitted, disad- vantageous as they are to the prospect of bringing the diagnosis of syphilis to a final settlement, so as to enable the writer to de- scribe the disease with accuracy, and the practitioner to recognize and treat it with certainty. The first essential step to the elucidation of this subject, however, is un- doubtedly the subversion of every doctrine relative to it, which is repugnant to gene- ral experience. The same facts, which may render it necessary for Mr. Carmichael to retract some of his inferences, and which have now been established beyond all doubt or possibility of successful contradic- tion, by the very impartial, disinterested, and extensive investigations, made in the army hospitals, would have obliged even Hunter himself, had he been alive, to con- fess the mistaken views which he some- times took of the nature of the venereal dis- ease. Among other doctrines, Mr. Hunter incul- cates, that “ the venereal matter, when taken into the constitution, produces an irritation which is capable of being continu- ed, independent of a continuance of ab- sorption, and the constitution has no poiver of relief ; therefore, a lues venerea continues to increase." The same criterion was pro- posed by Mr. Abernethy, who states, that the “ constitutional symptoms of the vene- real disease are generally progressive, and never disappear unless medicine be employ- ed.” ( Surgical Observations , p. 137.) And* notwithstanding some dissent may be tra- ced in both old and modern writers from the belief that mercury was absolutely es sential to the cure of the venereal disease,, and an opposite conclusion might easily have been drawn from the whole history of this subject, including the practice of for- mer and present times, the contrary hypo- thesis was that always taughtin all the great medical schools of this country, even down to so late a period as eight or ten years ago. But the error no longer prevails, and no facts are more completely established than that mercury, however useful it may fre- quently be in the treatment of the venereal disease, is not absolutely necessary for the cure either of the primary or secondary symptoms, and that the disease, so far from always growing worse, unless mercury be administered, alternately gets well, without the aid of this, or any other medicine. If any man yet doubt the general truth of this VENEREAL DISEASE 602 statement, let him impartially consider the many facts and arguments brought forward in proof of it in the writings of Mr. Fergus- son, Mr. Rose, Dr. Hennen, Dr. Thomson, Mr. Guthrie, Mr. Bacot, and other modern practitioners. In short, if there be such a sceptic now living in this country, let him peruse the returns made by the surgeons of the whole British army, documents which will be noticed in the sequel of this article ; let him consider the evidence of the sur- geons of other countries, especially that of Cullerier, who annually demonstrates to his class of pupils the cure of venereal ulcers without mercury ; and the testimony and practice of the German surgeons, who were attached during the war to regiments of their countrymen in the British service. The fact is therefore indisputable, that the venereal disease, in all its ordinary and di- versified forms, is capable of a spontaneous cure, and consequently, that the question, whether the disease is syphilitic or not, can never be determined by the circumstance of the complaint yielding, and being perma- nently cured, without the aid of mercury. Yet, as Mr. Rose has observed, the supposi- tion, that syphilis did not admit of a natural cure, and that mercury was the only reme- dy that had the power of destroying its virus, was of late so much relied upon, that where a disease had been cured without the use of that medicine, and did not afterward return, such fact alone, whatever might have been the symptoms, was regarded as suffi- cient proof that it was not a case of syphi- lis. And, as the same writer very judi- ciously remarks, the refutation of these no- tions is of considerable importance, “ not so much in reference to the treatment of syphilis under common circumstances, for the strikingly good effects of mercury will probably not render it adviseable in general to give up the use of that remedy, but from the change it will produce in our views of the diagnosis of the disease. The distinction which has engaged such a share of attention of late years, and which is evidently so im- portant between syphilis and syphiloid dis- eases, has been made to depend so much on the former admitting of no cure, except by mercury, that if this principle should be found to be erroneous, the difficulties which have attended it will in a great measure be explained.” (Med. Chir. Trans. Vol. 8, p. 350, 351.) That it is erroneous will appear more clearly when the treatment of syphi- lis falls under consideration. Excluding from present attention works of ancient date, it is curious to find how very near several writers, within the last twenty or thirty years, arrived at the same point to which recent investigations have led. Thus, Mr. B. Bell observes, a chancre might frequently be cured with external applications alone, and as we know from experience that the virus is not always ab- sorbed, the cure would in a few instances prove permanent ; but as we can never with certainty know whether this would happen or not, while, in a great proportion, of cases. there would be reason to think that absorp- tion would take place, we ought not in any case to trust to it.” (On Gonorrhoea Virulen - ta, tyc. Vol. 2, Ed. 2, p. 325, 8 vo. Edinb. 1797.) And, in some reflections upon a case of doubtful nature, Dr. Clutterbuck long ago remarked : “ Supposing even that the diseased appearances had after a time got well ot themselves, I should deem even this no absolute proof of their not being of a venereal nature. I have seen cases which induce me to believe, that the venereal dis- ease , in some of its stages, and in certain circumstances, may get well without mereury or any other remedy. But this is contrary to the doctrine of Mr. Hunter, who supposed that venereal actions go on increasing, with- out any tendency to wear themselves oat That lues venerea is much modified by cli- mate, and other circumstances, is generally allowed ; that it has been cured by other means than mercury, we have also very sufficient evidence in the older writers on. the subject : not to mention the late suc- cessful trials with acids and other substan- ces. Many of the appearances on the skin go off spontaneously. ‘ When purple spots ap- pear on the skin,” (Mr. Hunter observes, p, 319,) “ giving it a mottled appearance in this disease, many of the spots disappear, whilst others continue and increase.” (U. Clutterbuck , Remarks on some of the Opinions of the late Mr. John Hunter, p. 27, Sto. Lond. 1799.) If Dr. Clutterbuck had ad* vanced one step further, and declared that the venereal disease might be eured without mercury, or any other remedy, in all, or nearly all its forms, and not merely in some of them, he would actually have anticipa- ted the most important fact, recently esta- blished chiefly by the meritorious labours of the army surgeons, whose opportunities of making the investigation were better on several accounts than those of private prac- titioners, who generally soon lose sight of their patients, and never have them suffi- ciently under their control and observation to render a full perseverance in any method a matter of certainty. At all events, Dr. Clutterbuck may justly claim the merit of having distinctly marked the fact, that the circumstance of a disease giving way, and being cured without mercury, is no proof that the case is not venereal. One of the most ingenious theories ever devised for explaining all the perplexities and irregularities of syphilis, is unquestion- ably that of the late Mr. Hunter . for, it accommodated itself almost to every thing, and every believer in it fancied he could account satisfactorily for many puzzling occurrences which admitted of no good ex- planation on other principles. Mr. Hunter inculcated, that the parts contaminated by the absorption of the venereal poison, do not immediately begin to be palpably dis- eased, but only acquire a disposition to take on the venereal action. He further believed, that when this disposition was once formed in a part, it necessarily changed into action, or manifest disease, at some future period. VENEREAL DISEASE 603 .That mercury can cure the disease, when positively formed, but uot the disposition to it. That although mercury cannot destroy the disposition already contracted, yet that it can prevent it from being formed at all. That the disposition never becomes the real disease, or, in Mr. Hunter’s language, goes into action during the use of mercury. That the action having oncetaken place, always increases, never wearing itself out. That parts, once cured, never become again con- taminated from the same stock of infection. And, that the matter of secondary ulcers, or those which break out in consequence of absorption, is not infectious. What Mr. Hunter meant by the term disposition , I think is better explained than the grounds for the adoption of the theories connected with it, viz. the presumption of its being formed in all the parts capable of contami- nation ; the certainty of its future change into actual disease ; the impossibility of curing it by mercury previously to such a a change ; but the possibility of preventing its formation at all by the timely use of that remedy. Dr. Clutterbuck has well observed, that the only foundation for all these hypothe- ses, connected with the phrase disposition, is the fact, that secondary symptoms some- times arise, notwithstanding a fall use of mercury. If, says this gentleman, we were to suppose, with Mr. Hunter, that all the parts which are susceptible become at once contaminated, and mercury has no influence over them in this state, the constitution should become affected in almost all cases, for absorption probably always precedes the application of remedies. Either, there- fore, mercury does prevent the future action, or a more frequent absence of susceptibility to the disease must be supposed, than there are grounds for imagining. ( Remarks on the Opinions of Mr. Hunter , p. 9 — 12.) But, surgeons of the present day, enlightened by many new facts unequivocally determined since Mr. Hunter’s time, know very well that a disposition to the disease is in many instances not produced at all, even though the matter of a chancre be supposed to be absorbed, since in a large proportion of cases of chancres, which had all the charac- teristic appearances of such ulcers, accord- ing to Mr. Hunter’s own description, no secondary symptoms followed, though the patients were treated and cured without any mercury. Yet, if Mr. Hunter’s theory were true, the disposition must have been pro- duced, the action or disease itself in the form of secondary symptoms must have ensued, sooner or later, and no cure could have been ultimately effected without mer- cury. Fortunately fur mankind, unsound as some of the theories seem, which are attached by Mr. Hunter to the supposed disposition to the venereal disease, or its latent form, there w r as one piece of advice given by him, which may be said to have had a beneficial effect in practice, though founded upon these very doctrines ; and it was this, that we should push our medicine no farther than the cure of the visible effects of the poison, and allow whatever parts may be contaminated to come into action after- ward.” (On the Venereal Disease, p 334.) This maxim, I know, has been regarded by some admirers of long salivations as the cause of many relapses and imperfect cures ; but when 1 advert to the dreadful mischief, which formerly attended protracted courses of mercury for latent and imaginary com- plaints, my mind regrets that Mr. Hunter himself should not have adhered strictly in practice to his own principle, Irom which he undoubtedly deviated with his patients, and even in certain other parts of his wri- tings. However, the effect has been to discourage long courses of mercury j and, perhaps, in this way, the world has been benefited by the counsel, though not rigor- ously adopted by him who gave it. Con- fessing my own inability to reconcile the various theories, about the nature and effects of the venereal poison, to many facts, which are disclosed in practice, I shall now proceed to offer a few remarks on each of the primary and secondary symptoms. Chancres. The penis, as Mr. Hunter has observed, which in men is the common seat of a chancre, is, like every other part of the body, liable to diseases of the ulcerative kind, and, on some accounts, is rather more so than other parts. When attention is not paid to cleanliness, excoriations or superfi- cial ulcers often originate. The genitals, also, like almost every other part that has been injured, when once they have suffered from the venereal disease, are very liable to ulcerate again. Since therefore the penis is not exempted from common diseases, every judgment of the nature of ulcers upon it, as Mr. Hunter truly remarks, should be formed with great attention, particularly as all diseases upon this part are suspected to be venereal. But for a particular descrip- tion of the many ordinary complaints, which are apt to occur on the genitals, either pre- ceded or unpreceded by sexual intercourse, I refer to Mr. Evans’s treatise. (See Patho- logical and Practical Remarks on Ulcerations of the Genital Organs, 8 vo. Lond. 1819.) From facts already mentioned in this ar- ticle, however, it would appear that primary syphilitic ulcers or chancres, by which I imply sores capable of giving rise to the secondary symptoms of the venereal dis- ease, have no determinate external charac- ter, are extremely diversified in their appearance, and absolutely cannot be distinguished by their mere look from sores which are of a common, or at least a verv different nature. This is another important fact, for which every man in the profession who seeks only truth, and the expulsion of errors from the doctrines of surgery, must feel obliged to the army surgeons. Nor is their merit lessened by the consideration, t ,a< the detection of mistake on this point, like the discovery of the error, concerning the invariable progress of the venereal disease from bad to worse, unless medicU>e VENEREAL DISEASE. be given, Las taken place in opposition to the tenets of Mr. Hunter. “ Venereal ulcers (says he,) commonly have one character , which, however, is not entirely peculiar to them ; for many sores that have no dispo- sition to heal ( which is the case with a chancre ,) have so far the same character. Jl chancre has commonly a thickened base ; and, although in some, the common inflam- mation spreads much further, yet the specific is confined to this base." (P. 215.) And elsewhere, he observes, a chancre first be- gins with an itching in the part. When the inflammation is on the glans penis, a small pimple, full of matter, generally arises, without much hardness or seeming inflam- mation, and with very little tumefaction ; lor the glans penis is not so apt to swell in consequence of inflammation as many other parts are, especially the prepuce. Mr. Hunter also explains, that chancres, situated on the glans, are not attended with so much pain and inconvenience as sores of this nature on the prepuce. When chancres occur on the fraenum, or particularly on the prepuce, a much more considerable degree of inflammation soon follows, attended with effects more extensive and visible. These latter parts, being composed of very loose cellular membrane, afford a ready passage for the extravasated fluids. The itching is gradually converted into pain : in some cases the sdrface of the prepuce is excoriated, and afterward ulcerates; while, in other examples, a small pimple or ab- scess appears on the glans, and then turns into an ulcer. The parts become affected with a thickening , which at first, while of the true venereal kind , is very circumscribed ; not diffusing itself, as Mr. Hunter observes, gra dually and imperceptibly into the surround- ing parts ; but terminating rather abruptly. Its base is hard , and the e.dges a little promi- nent. When it begins on the fraenum, or near it., that part is very commonly wholly destroyed, or a hole is often made through it by ulceration. Mr. Hunter thought it better, in general, under the latter circum- stance, to divide the part at once. When the venereal matter is applied to the body of the penis, or front of the scro- tum, where the cuticle is thicker than that of the glans penis and prepuce, the chancre generally makes its appearance in the form of a pimple, w hich commonly forms a scab, in consequence of evaporation. The first scab is generally rubbed oil';, after which a second, still larger one, is produced. When the disease is more advanced, it is often attended with inflammation peculiar to the habit, becoming in many instances more diffused, and often producing phymo- sis and paraphvmosis. However, says Mr Hunter, there is yet a hardness around the sores, which is peculiar to such as are caused by the venereal virus, particularly those on the prepuce. Mr. Carmichael, also, in his arrangement of primary ulcers on the penis, considers the true chancre as being particularly dis- tinguished by its hardened base, which he compares to a piece of cartilage under the skin. It is to be observed, however, that Mr. Carmichael, by the true chancre, or primary syphilitic ulcer, does not signify that it is the only sore from which second- ary symptoms may arise ; but his observa- tions lead him to regard it as the cause of such constitutional effects as belong to w hat he deems the true form of syphilis, or that in which the use of mercury is the most de- cidedly indicated. It would give me sincere pleasure to find any agreement on this part of the subject among other observers. The reader, indeed, must already know r , that the hardened base, which both Hunter and Carmichael have regarded as a distin- guishing character of a true chancre, is not found to be so by other gentlemen, who have most impartially investigated this point. Thus, Dr. Hennen observes, “ we are not in possession of the knowledge of any invariable characteristic symptoms, by w^hich to discriminate the real nature of the primary sore, and w e are equally at a loss in many of the secondary symptoms. I am well aware that some practitioners have assumed to themselves the possession of a “ tactus eruditus,” by which they can at once distinguish a chancre, or a venereal ulcer, or eruption, in w hich mercury is in- dispensable, from one of a different nature ; but I have seen too many instances of self- deception to give them all the credit that they lay claim to. It would be by no means difficult to show that the high round edge, the scooped or excavated sore, the preceding pimple, the loss of substance, the hardened base and edge , whether circumscri- bed or diffused, and the tenaciously adhesive discharge of a very fetid odour, are all ob- servable in certain states and varieties of sores, unconnected with a venereal origin. The hardened edge apd base, particularly, can be produced artificially by the applica- tion of escharotics to the glans or penis of a sound person ; and if any ulceration, or warty excrescence, previously exists on these parts, this effect is still more easily produced.” (On Military Surgery, Ed. 2, p. 517.) Now, if it be asked, whether the chancre with a hardened base, and promi- nent edge, is distinguished by its not admit- ting of cure without mercury ? and by any regularity or peculiarity in the nature of secondary symptoms, when they originate from such an ulcer? modern experience denies the validity of both these criteria. If Mr. Rose’s excellent paper be consulted, the reader will see that this gentleman has certainly cured, without the aid of mercury, ulcers, which had a decidedly marked indu- ration of the margins and bases, by which the syphilitic chancre, according to Mr. Carmichael, is easily distinguished. (Med. Chir. Trans. Vol. 8 ,p. 42 R fyc. ; also Guth- rie, Vol. cit. p. 576.) And, us for the other points, sufficient evidence has already been detailed in the foregoing columns to satisfy any impartial mind, that, as far ns the eye can teach us, no kind of primary sore has yet been satisfactorily proved to be the VENEREAL DISEASE cause of only one set of peculiar constitu- tional symptoms ; but, on the contrary, that a great variety of appearances in the skin, throat, &.c. may follow sores, which, as far as external characters are concerned, seem exactly alike. The only partial exception to this remark is the great frequency of pa- pular eruptions alter superficial sores ; a point on which both Mr. Carmichael and JMr. Rose agree, though the latter gentleman does not represent even this connexion as constant. Mr. Hunter computed, that claps occur more frequently than chancres, in the proportion of four or five to one. 1 am not prepared to offer any opinion on this calcu- lation, in reference either to chancres, as defined by that interesting writer, or under the more comprehensive view of them, to which the results of modern investigations would lead. One intelligent writer, how- ever, has observed, that presftnt experience does not justify Mr. Hunter’s conclusion re- specting the infrequency of chancre com- pared with gonorrhoea. (J. Bacot, Obs. on Syphilis, p. 54.) Yet, in Dublin, if Mr. Car- michael’s statement be correct, the fre- quency of gonorrhoea, as compared with that of what is sometimes termed the true venereal chancre, must be so great as to defy all computation ; for he informs us, that since the descriptions of the success of the non-mercurial practice fell into his hands, he has been anxious to ascertain, by personal observation, whether true syphili- tic chancres did really admit of being cured without mercury ; but, says he, “ this dis- ease, as described by Hunter, has diminish- ed in so extraordinary a degree in this country, that, strange to say, I have from that period met with only one case of true chancre.” ( Observations on the Symptoms, fyc. of Venereal Diseases, p. 14.) As this chancre remained stationary a month, it was thought proper to employ mercurial frictions, and it then soon healed, leaving a callosity which continued two months longer. However, after the above passage wus written, Mr. Carmichael met with two cases of “ well marked chancre,” each of which w r as attended with psoriasis syphili- tica, scaly from its commencement. No mercury was given. For five weeks, the disease gained ground ; but, in the end, both cases were cured, merely sarsaparilla hav- ing been administered. The following observations, contained in the appendix to Mr. Carmichael’s work, do him infinite cre- dit. “ Although, (says he,) these two cases cannot fail to make a due impression, yet, if they stood alone, their evidence could not be deemed sufficient to establish a be- lief, that true syphilis, like the papular disease, is capable of yielding to the powers of the constitution, or to remedies in which mercury does not form an ingredient. But this deficiency seems to be, in a great mea- sure, supplied by the testimony, of Mr. Rose, Mr. Hennen, and other equally intelligent surgeons, who had the advantage of serving with our army on the continent ; and, if in the preceding pages I appear to he sceptical dOui with respect to the accuracy of their observa tions,and doubted that it wastrue chancre, and true syphilitic eruption, which yielded to their prescriptions, unaided by mercury, these two cases have satisfied me that every attention is due to the exactness and discernment of these respectable individuals ; and if 1 hesi- tated until 1 saw with my own eyes, and judged with m> own understanding, I claim for my own observations no larger a mea- sure of faith from others.” And he after- ward adds, “ In thus relinquishing my opi- nion, that true syphilis differs from oiher venereal complaints, by always requiring mercury for its cure, it is necessary to reduce the doctrine I hold to this propo- sition : that with respect to the use of that medicine, it differs from them only in not being injured, but decidedly benefited by it in all its symptoms and stages.” (P. 216, 219.) According to Mr. Hunter, there are three ways in which chancres may be produced ; first, by the poison being inserted into a wound ; secondly, by being applied to a non-secreting surface; and, thirdly, by be- ing applied to a common sore. A wound, it seems, is much more readily infected than a sore. To whichever of these three differ- ent surfaces the pus is applied, it produces its specific inflammation and ulceration, at- tended with a secretion of pus. The mat- ter produced in consequence of these dffer- ent modes of application, he says, partakes of the same nature as the matter which was applied, because, be observes, the irritations are alike. How the alleged examples of very different primary sores being sometimes communicated by the application of the maiter of chancre, are to be reconciled with the Hunterian doctrines, it is difficult to suggest, unless Mr. Carmichael’s obser vation about the present excessive rarity of the true syphilitic chancre, can furnish the explanation. However, as far as I can be- lieve my own eyes and judgment, I now see in London the same forms of chancre, which used to prevail during my apprentice- ship at St. Bartholomew’s Hospital more than twenty years ago. And if any differ- ence can be particularized, it is only that which depends upon their being less rarely converted into worse diseases than mere syphilitic ulceration, by the dreadful effects of immoderate courses of mercury. With respect to the three modes, in which Mr. Hunter speaks of the venereal poison being applied and taking effect, I know not why he should have altogether excluded se- creting surfaces; for of this nature (as a late writer remarks) are the glans penis and co- rona glandis, ( Bacot on Syphilis, p. 55,) and of a similar kind, are the insides of the labia, the surfaces of the nymphae, &ic. where sores are common enough. Whatever may be the truth of the impossibility of the forma- tion of chancres within the urethra, the latter considerations certainly tend to prove that the secreting nature of its membrane, is not the only reason for the alleged fact. I shall not here detain the reader with VENEREAL DISEASE. rulence from long continuance among us. But before we are altogether justified in drawing such a conclusion, we must forget all the* bad practice wnich prevailed in for- mer days, and hich, in my opinion, is suffi- cient to account tor the more severe forms in which syphilis then presented itself. According to Mr. Hunter’s ideas, the most simple method of treating a chancre is to extirpate it with caustic, or the knife, where- by it is reduced to the state of a common sore, or w’ound, and heal$ up as such. How- ever, he sanctions this practice only on the first appearance of the chancre, when the surrounding parts are not yet contaminated ; for, he says, it is absolutely ecessary to re- move the w’hole of the diseased part, and this object is exceedingly difficult of accomplish- ment, when the disease has spread considera- bly. When the chancre is situated on the glans penis, he thought touching the sore with the lunar caustic preferable to cuttim: it aw'ay, because the hemorrhage from the cells of the glans u 7 ould be considerable after the use of the knife The caustic should be pointed at the end like a pencil, in order that it may only touch 9uch parts as are really disease ; and its ap- plication should be repeated till the surface of the sore, after the separation of the last sloughs, assumes a red ancLhealthy appear- ance, w r hen it will heal, litce any other sore made with caustic. When tiie sore is on the prepuce, or the common skin of the penis, and in art incipient state, the same practice may be adopted w ith success When the chancre is large, how- ever, it cannot be destroyed with the argen- tum nitratura, which does cot extirpate the increasing sore deeply enough. In sucli cases, Mr. Hunter thought that the potassa cum calce might answer belter. When the caustic could not lie conveniently employed, this author sometimes recommended the ex- cision of chancres, a plan which he had adopted himself, and the part afterward healed with common dressings. However, says he. as our knowledge of the extent of the disease is not always certain ; a :d as this uncer amty increase; with the size of the chancre, the cure must he in some mea- sure promoted by proper dressings, and it will t»e prudent to dress the sore w ith mercu- rial ointment. When a chancre is destroyed almost immediately on its first appearance, Mr. Hunter believes lhat there is I i t tie dan- ger of the constitution being infected, as it is reasonable to conclude lhat there has not been time for absorption to take place. However, on account of the impossibility of being certain on this point, he recom- mends mercury to be given from motives of prudence, the quantity of which medicine, be says, should he proportioned to the dura- tion a, id progress of the sore. When the chancre is large, Mr. Hunter deems mercury absolutely necessary, and he conceives that very little good is to be done by the extirpa- tion. With respect to dressings for chancres, Mr. Hunter seems to have placed a good deal of confidence in those which contain mercury ; but I do not believe that the same attach- ment to them prevails non which existed twenty years ago. And the established fact of mercury not being absolutely necessary i i any way for the. cure of different venereal sores, must have the effect of removing some prejudices on this [mrt of the subject. As common mercurial ointment is always more or less rancid, I have found it in many cases a bad kind of dres ing ; and now never ap- ply it to ulcerated surfaces. In ordinary cases, I believe astringent lotions made w ith the sulphate of copper, acetate of lead, alum, &,c. answer the best. Some chancres are in- dolent, and require stimulants, like the hy- drargyri nitrico oxydurn blended with oint- ment, the unguentura hydrargyri nitrati more or less weakened, ora solution of the nitrate of silver. Mr. Hunter, always partial, even in cases of indolent chancres, to mercurial dressings expresses his preference to a salve containing calomel, as being more active than common mercurial ointment. In phage- denic and sloughing chancres, the carrot and fermenting poultices, solutions of the extracts of hemlock and opium ; hut particularly bread and water poultices with opium, and lotions of the arsemate of kali, nitrous acid, and nitrate of sliver, merit tiial. In general, Mr. Hunter was an advocate for changingthe dressings very often, because the matter separates them from the sore, so as to diminish their effects. He states, that changing the appli* at ions thrice a day, will not be found too often, particularly when they are in the form of an ointment. When the venereal nature of a chancre is removed, the sore frequently becomes eta- VENEREAL DISEASE 612 tionary, in which case Mr. Hunter observes, that new dispositions have been acquired, and the quantity of disease in the part ha£ been increased When chancres are only stationary, Mr. Hunter says, they may often be cured by touching them slightly with the lunar caustic. In these cases, no cica trization seems possible, till the contamina- ted surface, or the new tiesh which grows on that surface, has either been destroyed or altered. When sores are situated under the prepuce, where they are concealed by a phymosis, some emollient, or gently as- tringent lotion, should frequently be injected under the fore-skin, so as to wash out any matter which might otherwise lodge there, and cause additional irritation. Contrary to the doctrines, which the facts of modern experience have now fully esta- blished, Mr. Hunter believed, that mercury should be given in every case of chancre , hovv- ever slight, and even when it has been de- stroyed by caustic, or other means, on its very first appearance. The remedy, he says, should be continued for some time after the chancre has healed , in order to hinder the ve- nereal disposition from forming. Here we find even Hunter himself falling into some inconsistencies ; for, in other parts of his work, he seems to approve of the principle of giving mercury only when actual and visible disease exists, becau-e it cannot cure the disposition to it, even if it exists. Now, though the chancre is cured, no further ab- sorption of the virus from it is possible, and whatever disposition to the disease can arise from absorption, must have already been formed, and therefore cannot be prevented, and, according to Mr. Hunter’s own theory, the virus has been long ago expelled from the system, together with some of the ex- cretions, mercury is recommended with the view of protecting the constitution. How- ever, if Mr. Hunter’s explanations are not altogether satisfactory on this part of the subject, I believe the fault is in his theory, because, in cases where mercury is deemed adviseable, general experience appears to sanction the practice of continuing its use for some time after the chancre is perfectly healed. Yet many exceptions to this rule present themselves ; for, if a chancre is large, and very long in healing, its syphilitic character is generally extinct a good while before cicatrization is completed, and per- severance in mercury under these circum- stances would be both an absurd, and a dangerous practice. Hence, in a great measure, the cause of the numerous instances of the mercurial dis- ease, as Mr. Mathias has named it, and which, in former days, did far more mis- chief than syphilis itself. (See An Inquiry into the History and Nature of the Disease, produced in the Human Constitution by the Use of Mercury, 3d Ed 8 vo. Land. 1816.) This part of (lie subject is noticed by Mr. Hunter, who states, that in very large chan- cres, it may not always be necessary to continue cither the external or internal ad- ministration of mercury till the sore is healed ; for the venereal action is just as soon destroyed in a large chancre, as it is in a small one, since every part of the sore is equally affected by the medicine, and, of course, cured with equal expedition. But, in regard to cicatrization, circumstances are different, because a large sore is longer than a small one in becoming covered with skin. Hence, according to Mr. Hunter, a large chancre may be deprived of its venereal action, long before it has healed ; while, on the other hand, a small one may heal before the syphilitic affection has been destroyed. In the latter case, he represents it as most prudent, both on account of the chancre and constitution, to continue the employment of mercury a little vjhile after the sore is healed; advice which, as 1 have already stated, is at variance with certain parts of his own theory, however well justified it may be by experience. As Mr. Hunter has explained, chancres both in men and women often acquire, du- ring the treatment, new dispositions, w hich are of various kinds, some retarding the cure, and leaving the parts in an indolent thickened state, after the cure is accom- plished. In other instances, a new disposi- tion arises, which utterly prevents the parts from healing, and often produces a much worse disease than that from- much it ori- ginated. Such new dispositions may lead to the growth of tumours. They are more frequent in. men than women, and generally occur only when the inllammation has been violent from some peculiarity of the parts, or constitution. They have sometimes been considered as cancerous. Among the diseases in question, Mr. Hun- ter notices those continued, and often in- creased inflammations, suppurations, and ulcerations, which become diffused through the whole prepuce, and also, along tile common skin of the penis, which becomes of a purple hue, attended with such a gene- ral thickening of the cellular membrane, as makes the w'hole organ appear considerably enlarged. The same writer observes, that the ulceration on the inside of the prepuce will sometimes increase, and run between the skin and the body of the penis, and eat holes through different places, till the whole is reduced to a number of ragged sores. The glans often shares the same fate, till more or less of it is gone. Frequently, the urethra in this situation is wholly destroyed by ulceration, and the urine is discharged some way farther back. The ulceration, if unchecked, at length destroys all the parts. In this acute case, prompt relief is demand- ed ; but often the proper mode of treatment cannot be at once determined, owing to our ignorance in r^pect to the exact nature of the peculiar cause of the disease. Mr Hunter states, that the decoction of sarsa- parilla is often of service, when given in large quantities ; and that the extract of hemlock, and sea bathing, are sometimes capable of effecting a cure. According to my own experience, the omission of mer cury is here the most essential thing. VENEREAL DISEASE Glo Sometimes alter a chancre has healed, the cicatrix breaks out again, and puts on the appearances of the preceding sore. Occasionally, similar diseases break out in different places from that of the cicatrix. Mr. Hunter believes, that they differ from a chancre in generally not spreading so fast, nor so far; in not being so painful, nor so much inflamed ; in not having such hard bases as venereal sores have ; and in not producing buboes. This writer is of opi- nion, that- they are not venereal, and he states, that they' are very apt to recur. Mr. Hunter does not specify any particular mode of cure for all these cases ; but he mentions one instance, which seemed to be cured by giving forty drops of the liquor potassae, every evening and morning, in a basin of, broth ; and he adverts to another case, which was permanently cured by sea- bathing. In some instances, after a chancre has healed, the parts, as Mr. Hunter remarks, do not ulcerate ; but appear to become thickened and indurated. Both the glans and prepuce seem to swell, so as to form on the end of the penis a tumour, or excres- cence, shaped very much like a cauliflower, and when cut into, showing radii, running from its base, or origin, towards the exter- nal surface. It is extremely indolent, and not always a consequence of the venereal disease; for Mr. Hunter has seen it arise spontaneously'. No medicine seems to be at all likely to cure the disease ; the only successful means is to amputate a considerable part of the penis, and then to keep a proper catheter introduced in the urethra. Another disposition, induced by the pre- vious occurrence of chancres, is that to ex- crescences, or cutaneous tumours, called warts. These are frequently considered not simply as a consequence of the venereal poison, but as possessed of its specific dis- position, and therefore, says Mr. Hunter, surgeons have recourse to mercury for the cure of them ; and it is said, that such treat- ment often removes them. This eminent practitioner never saw mercury produce this effect, although the medicine was given in sufficient quantity to cure recent chan- cres, and a lues venerea, in the same person. (See Wart.) Mr. Hunter takes notice of sloughs, which occur in the tonsils, from the effect of mer- cury on the throat, and are apt to be mis- taken for venereal complaints. He also mentions that, sometimes, when the original chancre has been doing well, and been nearly healed, he has seen new sores break out on the prepuce, near the first, and as- sume all the appearance of chancres. When, in the treatment of chancres, a bubo arises, while the constitution is under the influence of a sufficient quantity of mercury to cure such sores, which medicine has also been rubbed into the lower extre- mity, on the same side as the bubo, Mr. Hunter suspects, that the swelling in the groin is not venereal, butis produced by' the mercury. In these cases, he always pre- ferred conveying mercury into the system in some other manner. With respect to the treatment of chancres in women, since it is difficult to keep dress- ings on the parts, Mr Hunter advises the sores to be frequently washed with some mercurial soluti n, and speaks of one made with oxymuriate of mercury, as perhaps being the best, since it will act as a specific, and stimulant also, when this is requisite. When the chancres, however, are irritable, they are to be treated in the same manner as similar complaints in men. When the sores extend into the vagina, this passage must be kept from becoming constricted, or closed by the introduction of lint. Sometimes, after a chancre and all vene- real disease are cured, the prepuce continues thickened and elongated, so that the glans cannot be uncovered. Perhaps, the case is often without remedy. Mr. Hunter, how- ever, very properly recommends trying every possible means, and he informs us, that the steam of warm water, hemlock fomentations, and cinnabar fumigations, are frequently of singular service. When the thickeniug and enlargement of the prepuce cannot be removed by appli- cations, all the portion, anterior* to the glans penis, may be cut away. (See Phy- mosis .) Bubo. The immediate consequence of a chancre, which is called a bubo, and also the remote effects, implied by the constitu- tional, , or secondary symptoms , arise from the absorption of recent venereal matter from some surface, where it has either been ap- plied or formed. We are already aware, that Mr. Hunter believed the matter of gonorrhoea to be ca- pable of communicating the venereal dis- ease. Hence, he explains in the following terms, the three ways in which he thought a bubo might arise in consequence of absorp- tion. He observes, that the first and most simple manner, is when the matter, either of a gonorrhoea, or chancre, has only been applied to some sound surface, without having produced any local effect on the part; but has been absorbed, immediately after its application. Mr. Hunter affirms, that he has seen instances of this kina, though he confesses that they' are very rare, and that, in most cases apparently of this nature, a small chancre may be found to have existed. The second mode of absorption, or that taking place in a gonorrhoea, Mr. Hunter represents as more frequent. That second ary symptoms do occasionally follow go- norrhoea is yet commonly admitted, though whether they differ essentially from those which follow true chancres, is a point not yet completely settled. However, as far as Mr Carmichael’s experience goes, there is a difference, a part of which consists in the eruption being of the papular kind, as it is also after many instances of simple pri- mary ulcers. (See Obs. on the Symptoms, be. of Venereal Diseases , 8vo. Land. 1818.' 014 VENEREAL DISEASE The thira mode is (he absorption of mat- ter from an ulcer, which may either be a chancre, or a bubo. This mode is by far the most common, and it proves, with many other circumstances, that a sore, or ulcer, Is the most favourable for absorption. Mr. Hunter believed, that absorption was more apt to take place from sores on the prepuce, than those on the glans. A fourth mode of absorption from a wound is also an occasional occurrence. Mr. Hunter notices, that what is now commonly understood by a bubo, is a swell- ing, taking place in the absorbing system, especially in the glands, and arising from the absorption of some poison, or other irritating matter. When such swellings take place in the groin, they are calle^l bu- boes, whether they proceed from absorption or not. Mr. Hunter regards every abscess in the absorbing system as a bubo, whether in the vessels, or the glands, when it originates from the absorption of venereal matter. The matter is taken up by the absorbent vessels, and is conveyed by them into the circulation. In its passage through these vessels, it often affects them with the spe- cific inflammation. The consequence is the formation of buboes, which are vene- real abscesses. These are exactly similar to a chancre in their nature and effects, the only difference being in resard to size. As the lymphatic vessels and glands are irrita- ted by the specific matter, before it has un- dergone any change in its passage, the Inflammation produced, and the matter se- creted, partake of the specific quality. Inflammation of the absorbent vessels themselves is not nearly so frequent, as that of the glands. In men, such inflammations, in consequence of chancres upon the glans, or prepuce, generally appear like a cord, leading along the back of the penis from the sores. Sometimes, the absorbents inflame, in consequence of the thickening and exco- riation of the prepuce in gonorrhoea. The indurated lymphatics often terminate insen- sibly near the root of the penis, or near the pubes; while, in other instances, they ex- tend further to a lymphatic gland in the groin. Mr. Hunter believed, that this affec- tion of the absorbent vessels is truly venereal. The formation of a hard cord, he conceived, arose from a thickening of the coats of the absorbents, and from an extravasation of coa- gulable lymph on their inner surface. A cord, of the above kind, often suppu- rates, sometimes in more places than one, so as to form one, two, or three buboes, or small abscesses in the body of the penis. Inflammation much more frequently aftects the absorbent glands, than the vessels. The structure of the former parts appear to con- sist of the ramifications and reunion of the absorbent vessels. From this structure, ob- serves Mr. Hunter, we may reasonably sup- pose, that the fluid absorbed is in some mea- sure detained in the glands, and thus has a greater opportunity of communicating the / disease to them- than to the distinct vessel?. * Swellings of the absorbent glands may originate from other diseases, and should be carefully discriminated from those which arise from the venereal poison. With this view, Mr. Hunter advises us first to inquire into the cause, in order to ascertain whether there is any venereal complaint at some greater distance from the heart, such as chancres on the penis, or any preceding^dis- ease in this situation. He recommends us to inquire, whether any mercurial ointment has been at all applied 10 the leg and tnigh on the diseased side ; for mercury applied to those parts for the cure of a chancre, will sometimes cause glandular enlargements, which are occasionally mistaken for vene- real buboes. This irritation of the inguinal glands by the mechanical action of mer- curial ointment, has also been particularly noticed by Professor Assalini, who states, that he has had frequent opportunities of convincing himself of the fact. (See Manuale di Chirurgia, p. 67.) Mr. Hunter reminds us to observe, whether there has been any preceding disease in the constitu- tion, such as a cold, fever, &ic. The quick or slow progress of the swelling is likewise to be marked, and the tumour must be distin- guished from femoral hernia, lumbar ab- scesses, and aneurisms of the crural artery. In particular cases, it would appear, that some time elapses ; before (he venereal mat- ter produces its effec ts on the absorbent glands after its absorption. Mr. Hunter no- tices, that, sometimes, at least, six days transpire first ; a circumstance, which can only be known by the chancres having healed six days before the bubo began to appear. However, as the last matter of a chancre is probably not venereal, he infers, that in cases of this kind, absorption must have taken place earl ier than other considera- tions would lead one to suppose. Accord- ing to Mr. Hunter, in general, only the glands nearest to the seat of absorption are attacked. Thus, when the matter is taken up from the penis in men, the inguinal glands are affected ; and when from the vulva in women, those glands swell which are situated between the labium and thigh, and the round ligaments. It was one of Mr. Hunter’s opinions, that only one gland at a time is commonly affect- ed by the absorption of venereal matter. If this sentiment be correct, the circumstance may be considered as a kind of criterion be- tween venereal and other buboes. The second order of lymphatic vessels and glands are never affected ; as, for instance, those along the iliac vessels, or back. Mr. Hunter informs us, that he also observed, that when the disease was contracted by a sore, or cut upon the finger, the bubo occurred a little above the bend of the arm, by the side of the biceps muscle, and no swelling of this sort formed in the arm-pit. How- ever, he had heard of a fevv rare cases, in which a swelling in the axilla was also produced. When buboes arise from a venereal dis- ease on the penis? they are situated in the VENEREAL DISEASE GIG glands of the groin. When a bubo arises from a gonorrhoea, either groin may be attacked. But when the disease originates from a chancre, the bubo most frequently takes place in the nearest groin. The situation of the absorbent glands, how- ever, is not always exactly the same, and the course of the lymphatics therefore is sub- ject to some variety. Hence, Mr. Hunter has seen a venereal bubo, produced by a chancre on the penis, situated a considerable way down the thigh ; he has also often seen buboes as high as the lower part of the belly, before Poupart’s ligament . and sometimes near the pubes. At the present day, swell- ings of the femoral glands are never consi- dered venereal. The seat of absorption is more extensive in the female sex, and the course of some of the absorbents is also different. Hence, buboes in women may occur in three situa- tions, two of which are totally different from those in men When chancres are situated forwards, near the meatus urinarius, nympha?, clitoris, labia, or mons veneris, the absorbed matter is generally conveyed along one, or both of the round ligaments, and the buboes are formed in those ligaments, just before they enter the abdomen. Mr. Hunter suspected such buboes not to be glandular ones, but only inflamed absorbents. When chancres are situated far back, near or on the perinaeum, the absorbed matter is carried forward along the angle, between the labium and the thigh, to the glands in the groin, and often, in this course, small buboes are formed in the absorbents similar to those abscesses which occur on the penis in men. When the effects of the poison do not rest iiere, a bubo in the groin may be occasioned in the same manner as in men ( Owing to the difficulty of being sure, that women are quite free from infection, it is often more difficult to decide in them, than in men, whether a bubo is venereal, or not. In men, who have had no local complaint, the bubo can only be venereal, when direct absorption from the surface of the skin has taken place. A bubo, says Mr. Hunter, commonly be- gins with a sense of pain, which leads the patient to examine the part, where a small hard tumour is to be felt. This increases, like every other inflammation, that has a tendency to suppuration, and unless check- ed, pus forms, and ulceration follows, the matter making its way to the skin very fast. The above celebrated writer remarks, however, that there are some cases, which are slow in their progress. This circum- stance he imputes either to the inflammatory process being kept back by mercury, or other means, or to its being retarded by a scrofulous tendency. The inflammation, he says, is at first con- fined to the gland, which may be moved about in the cellular membrane ; but when the part has become enlarged, or when the inflammation, and suppuration, are more advanced, the surrounding parts become more inflamed, and the tumour is more dif- fused. Some buboes become complicated with an erysipelatous and cedematous affec- tion, by which they are rendered more dif- fused, and less disposed to suppurate. Mr. Hunter allows, that to distinguish, with certainty, the true venereal bubo from other swellings of the glands in the groin, may be very difficult. He represents the true venereal bubo, in consequence of a chancre, as being most commonly confined to one gland. It preserves Us specific dis- tance till suppuration has taken place, and then becomes mure diffused. It is rapid in its progress from inflammation to suppura- tion and ulceration. The suppuration is commonly large, considering the size of the gland, and there is <»nly one abscess. The pain is very acute, and the inflamed part of the skin is of a florid red colour. Mr. Hunter describes such buboes as arise without any visible cause, as being of two kinds. One sort inflame and suppu- rate briskly. These he always suspected to be venereal, although he allows there was no proof of it, and only a presump- tion deduced from the quick progress of the disease. The second kind are generally preceded, and attended with slight fever, or the com- mon symptoms of a cold, and they are generally indolent and slow in their progress. If they are quicker than ordinary, they become more diffused than venereal buboes, and they are often not confined to one gland. When very slow, they give but little sensation ; but, when quicker, the sen- sation is more, acute, though not so much so as in venereal cases. They usually do not sup- purate. and often become stationary. When they do suppurate, it is in a slow manner, and frequently in more glands than one, while the inflammation is more diffused, and not considerable, in relation to the swelling. The matter makes its way to the skin slowly, and the part affected is of a more purple colour. Sometimes, the abscesses are very large, yet not painful. In considering whether the swellings of the inguinal elands are, or are not venereal, the first thing to be attended to is, whether, or not, there are any venereal complaints. If there are none, Mr. Hunter observes, that there is a strong presumptive proof, that the swellings are not venereal. When the swelling is only in one gland, very slow in its progress, and gives but little, or no pain, it is probably merely scrofulous. However, when the swelling is considerable, diffused, and attended with some inflammation and pain, the constitution is most probably af- fected with slight fever, the symptoms of which are lassitude, loss of appetite, want of sleep, small quick pulse, and an appearance of approaching hectic. Such swellings are long in getting well, and do not seem to be affected by mercury, even when very early applied. Mr. Hunter mentions his having seen the above affection of the groin, together with the constitutional indisposition, take place VENEREAL DISEASE. *ilO where there were chancres ; and he was puzzled to determine, whether the disease in the groin was sympathetic, from derange- ment of the constitution, or whether it arose from the absorption of matter. He had long suspected, that there was a mixed case, and was at last certain, that such a case might prevail. He had seen instances, in which the venereal matter, like a cold, or fever, only irritated the glands to disease, producing in them scrofula, to which they were disposed. In such cases, says Mr. Hunter, the swell- ings commonly arise slowly, give but little pain, and if mercury be given to destroy the venereal disposition, their progress is acce- lerated. Some suppurate while under this resolving course ; and others, which proba- bly had a venereal taint at first, become so indolent, that mercury has no effect upon them, and in the end, they either get well of themselves, or by other means. According to Mr. Hunter, buboes are local complaints. TREATMENT OF BUBOES. When a bubo is judged to be venereal, and only in an inflamed state, an attempt is to be made to resolve the swelling. The propriety of the attempt, however, depends on the progress which the disease has made. If the bubo be very large, and suppuration appears to be near at hand, resolution is not likely to be effected. When suppuration has already taken place, Mr. Hunter much doubted the probability of any success at- tendingthe endeavour, which now may only retard the suppuration, and protract the cure. The resolution of these inflammations, says Blr. Hunter, depends principally on mercury , and almost absolutely on the quantity , which can be made to pass through them. When suppuration has taken place , the cure also de- pends on the same circumstances. Hence, he recommended the mercury to be applied to such surfaces as allow the remedy, when absorbed, to pass through the diseased gland. In this manner, he conceived, that the dis- ease in the groin might be subdued, and that the constitution would be less likely to be contaminated. At the same time, he admit- ted, that the situation of many buboes is such, as not to have much surface for ab- sorption beyond them ; for instance, the bu- boes on the body of the penis, arising from chancres on the glans, or prepuce. As venereal buboes are an effect, or conse- quence of chancres, or venereal sores, and glandular swellings in the groin may take place from other kinds of sores, or local ir- ritations, and even from various constitution- al causes, while modern surgeons profess their incapacity always to pronounce the character either of a primary sore, or a bubo, by its first appearance, and progress, it is evident, that the same difficulties pre- sent themselves here, as in cases of primary sores, respecting the principles, by which rhe treatment should be guided. It is like- wise to be remembered, that buboes, when supposed to be decidedly syphilitic, are not , as Mr. Hunter imagined, absolutely incurable without mercury. The firm confidence also, which Mr. Hunter had in the doctrine of the benefit derived from the practice of rubbing mercury into surfaces, from which it would be conveyed directly to the diseased glands, so as both to resolve the swelling and pre- serve the constitution, is not now regarded as an unquestionable subject. As Mr. Bacot has judiciously remarked, there is some in- consistence in Mr. Hunter’s own statements upon this point •, for, in one place he affirms, that mercury, applied to the legs and thighs for the cure of a chancre, will sometimes cause, instead of disperse, a bubo. (P.404.) And Mr. Bacot believes himself, that mer- cury as frequently promotes the suppuration of buboes, as their dispersion. (On Syphilis , p 74.) And, respecting the practice of try- ing to make the mercury pass through the diseased glands, Mr. Hunter rather contra- dicts himself in another page, where he con- fesses his own doubts of its utility in suppu» rated buboes. However, Mr. Hunter ad- mits, that mercury alone is not always capa- ble of effecting the cure of such buboes as are deemed venereal ; and when the inflam- mation rises very high, he approves of bleed- ing, purging, and fomentations. When the inflammation is erysipelatous, he has a high opinion of bark; and, when it is scrofulous, he praises hemlock, and poultices made with sea-water. He was also aware of the fact of emetics sometimes occasioning the ab- sorption of the matter of buboes, after it is distinctly formed. If there is generally great difficulty in pronouncing at first the nature of a primary sore, as to the question of its being syphilitic or not, the same difficulty must occur with respect to judging of the glandularswellings, excited by it. And, on this account, and from the encouraging circumstances, that all buboes may be cured without mercury, and that the course of the venereal disease, unresisted by that mineral, is not so terrible and incurable, as used to be supposed, some surgeons, instead of having immediate re- course to mercury, prefer a little delay, in order to see, whether the swelling will sub- side, or not, under the use of common an- tiphlogistic means. Thus, Dr. Hennen dis- approves of using mercury immediately a bubo presents itself ; and he states, that the same principles, which guide him in the pri- mary ulcers, would have the same, if not greater force, in the case of buboes. “ In their irritable state (says he) I consider mer- cury altogether inadmissible.” (On Military Surgery, Ed. 2 ,p. 518.) Although the correctness of some of the principles, by which Mr. Hunter regulated his practice in buboes, must now be ques- tionable, inasmuch as he calculates too much on the absolute necessity for mercury, and on the usefulness of making it pass through the diseased glands, I conceive, that some of his directions are yet too important to excluded from this work. He sayr : VENEREAL DISEASE. 017 'quantity of mercury, necessary for the reso- lution of a bubo, must be proportioned to the obstinacy of the complaint ; but that care must be taken not to extend the employment of the medicine so far as to produce certain effects on the constitution. When the bubo is in a situation, which admits of a large quantity of mercury being rubbed in, so as to pass through the swelling, and when the com- plaint readily yields to the use of half a drachm of mercurial ointment, every night, the mouth not becoming sore, or at most, only tender, Mr. Hunter thinks it sufficient to pursue this course, till the gland is redu- ced to its natural size. In this manner, the constitution will probably be safe, provided thfe chancre, which may have caused the bubo, heals at the same time. When . the mouth is not affected in six, or eight days, and the gland does not readily resolve, then two scruples, or a drachm, may be applied every night ; and, continues Mr. Hunter, if there should still be no amendment, even more must be rubbed in. In short (says he) if the reduction is obstinate, the mercury must be pushed as far as can be done with- out a salivation. When there is a bubo on ea^li side, so much mercury cannot be made to pass through each, as the constitution in general will not bear this method. However, Mr. Hunter sanctions the plan of minding the soreness of the mouth less in this kind of case ; though, he adds, that it is belter to let the bu- boes proceed to suppuration , than to load the system with too much merewry. When the situation of buboes will not al- low an adequate quantity of absorbed mer- cury to pass through them, the frictions must be continued in order to affect the con- stitution ; but, according to Mr Hunter in this case, more mercury will be requisite, than when the remedy can be made to pass directly through the diseased gland ; an as- sertion, which may now be doubted. Many buboes remain, without either co- ming to resolution, or suppuration ; and, notwithstanding every attempt to promote these changes, the glands become hard and scirrhous. Mr. Hunter conceived, that these cases are either scrofulous at first, or be- come so as soon as the venereal disposition is removed. He advises the use of hemlock, sea-water, poultices, and sea-bathing. According to a modern surgeon, of judg- ment and considerable experience, when buboes are in a chronic stationary state, the application of blisters to the swelling is at- tended with the most beneficial effects. And, lie rightly observes, that when such tumours are extremely hard and indolent, it is more advantageous to let the patient have the be- nefit of the open air, exercise, and his ac- customed mode of living, than to confine him in an hospital. ( Jlssalini , in Manuals di Chirurgia , p. 64 ; Milano, 1812.) Stimula- ting the skin with the antimonial ointment, is also sometimes a good practice. The suppuration of buboes frequently can- not be prevented by any known means. They are then to be treated, in some re- Vot, II ' 7* spects, like any other abscess. Before open- ing buboes, Mr. Hunter conceived it advan- tageous to let the skin become as thin as possible, because a large opening would then be unnecessary, and no measures re- quisite for keeping the skin from closing, before the bottom of the sore had healed. Mr. Hunter was doubtful , whether the ap- plication of mercury should be continued through the whole suppuration. He was in- clined to continue it ; but, in a smaller quan- tity. There has been much dispute, whether a bubo should be opened, or allowed to burst of itself, and whether the opening should be made with a cutting instrument, or caustic. On this subject, Mr. Hunter remarks, that there is no peculiarity in a venereal abscess to make one practice more eligible than another. The surgeon, he says, should be guided in some degree, by the patient. Some patients are afraid of caustics ; others, of cutting instruments. But, when the surgeon has the choice, Mr. Hunter expresses a pre- ference to opening the bubo with a lancet, in which method, no skin is lost. But he observes, that w r hen a bubo is very large, and there will be a great deal of loose skin, after the discharge of the matter, he thinks, that caustic may,' perhaps, be better, as it will destroy some of the redundant skin, and occasion less inflammation, than what is caused by an incision. The potassa cum calce is the caustic commonly employed. After the bubo has been opened, surgeons usually poultice it, as long as the discharge and inflammation are considerable, and then they employ dressings, which must be of a quality, adapted to circumstances. In the mean while, mercury is continued, both to make the bubo heal, and prevent the bad effects, which might otherwise arise from the matter being continually absorbed. The mercurial course is to be pursued, till the sore is no longer venereal. But, in ge- neral, since this point is difficult to ascer- tain, Mr. Hunter advises the continuance of mercury till the part has healed, and even somewhat longer, if the bubo has healed very quickly ; for, the constitution is apt to become contaminated. However, he did not approve of this long use of mercury in all cases; because buboes often assume, be- sides the venereal, other dispositions, which mercury cannot cure, and will even exas- perate. Sometimes thesores, whentheyarelosing, or entirely deprived of the venereal disposi- tion, become changed into ulcers of another kind, and, most probably of various kinds. How far it is a disease arising from a vene- real taint, and the effects of a mercurial course jointly, says Mr. Hunter, is not cer- tain. He suspected, however, that the na- ture of the part, or constitution, had a prin- cipal share in the case, and, I believe, few surgeons of the present time entertain any doubt of the abuse of mercury being a very frequent cause, independently of any other circumstance. (See Mathias on the Mercuri- al Disease. Ed. 3.) VENEREAL DISEASE. CIS Mi'.v Hunter observes, Ilia! sue]) diseases make the cure of the venereal affection much more uncertain, because, when the sore be- comes stationary, or the mercury begins to disagree, we are ready to suspect that the virus is gone ; but, this (he supposes) is not always the case. He had seen some buboes exceedingly painful and tender to almost every thing that touched them, and the more mild the dressings were, the more pain- ful the parts became. In some instances, the skin alone becomes diseased. The ulceration spreads to the surrounding integuments, while a new skin forms in the centre, and keeps pace with the ulceration, so that an irregular sore, which Mr. Hunter compares with a worm- eaten groove, is formed all round. It ap- pears only to have the powerof contamina- ting the parts, which have not yet been af- fected ; and those which have, readily heal. According to the same author, when buboes become stationary, and are little inclined to spread, attended with a sinus, or two, hem- lock, joined with bark, is the medicine most frequently serviceable. It is to be used both externally and internally. Mr. Hunter also speaks favourably of sarsaparilla, sea-bath- ing, and sea-water poultices. He states, that at the Lock Hospital, gold refiners’ wa- ter has been found an useful application ; and that in some cases, benefit has arisen from drinking large quantities of orange- juice, and from the use of mezereon. Lues venerea. Surgeons imply, that a lues venerea has taken place, when the vene- rea! virus has been absorbed into the circu- lation. Mr. Hunter does not think the epi- thet constitutional strictly proper in its ap- plication to this form of the venereal disease. By constitutional disease, he observes, he should understand that, in which every part of the body is acting in one way, as in fevers of all kinds ; but, the venereal poison seems to be only diffused through the circulating fluids, and, as it were, to force certain parts of the body to assume the venereal action, which action is perfectly local. To use Mr. Hunter’s phrase, it takes place in different parts in a regular succession of susceptibili- ties. Only a few parts are acting at the same time ; and a person may be constitu- tionally affected in this way, and yet almost every function may be perfect. The venereal poison is generally conveyed into the system from a chancre. It may, also, according to Mr. Hunter’s doctrine, be absorbed from a gonorrhoea. There is like- wise a possibility of its getting into the cir- culation from the surface of the body, with- out any previous ulceration. According to his doctrine, it may bo absorbed from com- mon ulcers, without necessarily rendering them venereal ; and it may be taken up from wounds, in which cases, it generally first causes ulceration. Venereal ulcers. In consequence of the blood being contaminated with real venereal pus, it might be expected that the local effects thi s produced, would be similar in their nature to those producing them. Mr. Hunter believed, that this is not the case, lie notices, that the local effects from a constitutional contamination, are all of one kind, viz. ulcers, let the effects make their appearance on any surface whatever, either the throat or common skin. But Mr. Hun- ter conceived, that if the matter, when in the constitution, were to act upon the same specific principles, as that which is exter- nally applied, a gonorrhoea would arise, when it affected a canal, and only sores, or chancres, when it attacked other surfaces. Mr. Hunter found, that even the sores which are caused in the throat are very dif- ferent from chancres. He says, lhat the true chancre produces considerable inflam- mation, often attended with a great deal of pain, and quickly followed by suppuration. But the local effects, arising from the virus in the constitution, are slow in their pro- gress, attended with little inflammation, and are seldom or never painful, except in particular parts. However, Mr. Hunter allows that this sluggishness in the effects of the poison depends on the nature of the parts diseased ; and he owns that, when the tonsils, uvula, or nose, are affected, the progress of the morbid mischief is rapid, and bears a greater resemblance to a chancre than when it occurs on the skin. Even in those parts Mr. Hunter thought that the ulcers were attended with less inflamma- tion than chancres which were spreading with equal celerity. Before the time of Mr. Hunter, the matter, secreted by sores which arise from a consti- tutional infection, was always considered to be of a poisonous quality, like the matter of a chancre. At first, one would expect that this must actually be the case, because venereal matter is the cause, and mercury cures chancres, and also ulcers proceeding from a lues venerea. Mr. Hunter remarks, however, that the latter circumstance is not a decisive proof, since mercury is capable of curing many diseases , besides the venereal. He also takes notice, that when pus is ab- sorbed from a chancre, if generally produ- ces a bubo ; but that a bubo is never occa- sioned by the absorption of matter from a venereal sore, arising from the virus diffu- sed in the circulation. For instance, when there is a venereal ulcer in the throat, no buboes occur in the glands of the neck ; when there are syphilitic sores on the arms, or even suppurating nodes on the ulna, no swellings form in the glands of the armpit, although these complainis occur when fresh venereal matter is applied to a common sore on the arm, hand, or fingers. No swell- ing is produced in 1 lie groin in consequence of nodes, or blotches on the legs and thighs. Some very important experiments arc related in Mr. Hunter’s Treatise on the Ve- nereal Disease, in order to prove that the matter from a gonorrhoea, or clmncrc, is capable of affecting a man locally, who is already labouring under a lues venerea, and that the matter from secondary syphilitic sores has not the same power. The parti- ’ VENEREAL DISEASE 610 culars, however, are too long to be inserted in this book. Parts most susceptible of the Lues Venerea, fyc. Some parts of the body seem to be much less susceptible of the lues venerea than others ; indeed, Mr. Hunter observes, that, as far as our knowledge extends, cer- tain parts cannot be affected at all. The brain, heart, stomach, liver, kidneys, and several other viscera, have never been known to be attacked by syphilis. The first order of parts, or those which become affected in the early stage of the lues venerea, are the skin, tonsils, nose, throat, inside of the mouth, and sometimes the tongue. The second order of parts, or those which are affected at a later period, arc the peri- osteum, fasciae, and bones. Mr. Hunter conceived, that one great rea- son of the superficial parts of the body suf- fering the effects of the lues venerea sooner than the deep-seated ones, depends on the former being more exposed to external cold. He remarked, that even the second order of parts do not all become diseased at the same time, nor every where at once. But. on tlfe contrary, such as are nearest the external surface of the body are first disea- sed, as, for instance, the periosteum, bones of the head, the tibia, ulna, bones of the nose, &c. Neither does the disease affect these bones equally on all sides ; but first on that side which is next to the external surface. It was Mr. Hunter’s belief, how- ever, that the susceptibility of particular bones did not altogether depend upon their nearness to the skin ; but upon this cir- cumstance and their hardness together. The foregoing account by no means agrees with the results of modern inquiries into the nature of the venereal disease ; for, unless mercury be given, it appears that the bones are very seldom affected by it. Thus in the cases which were treated by Mr. Rose without mercury, he observes, that u the constitutional symptoms were evi- dently not such as could be regarded as ve- nereal, if we give credit to the commonly received ideas on the subject. Caries of the bones, and some of the least equivocal symptoms, did not occur. In no instance was there that uniform progress, with un- relenting fury, from one order of symptoms and parts affected to another, which is con- sidered as an essential characteristic of true syphilis.” (Med. Chir. Trans. Vol. 8, p. 423.) We learn also from Mr. Guthrie, that the bones were not affected in any of the cases, cured entirely without mercury in the York Hospital, though there were several other cases admitted, “ in which a few mercurial pills had been taken, and the mouth not affected, and in which the primary symp- toms were followed by eruptions both pa- pular and scaly, by ulcers in the throat, by nodes , and, in one case, by inflammation of the periosteum covering the bones of the nose, and ulceration of the septum nasi, although mercury was resorted to for its cure.” ( Vol. cit. p. 560.) In the examples treated without mercury, under the superintendence of Dr. Henncn, this gentleman did not see “ a single case in which the bones of the nose were affected : some cases of periostitis, and of pains and swellings of the bones of the cranium and ext renAties were met with ; but, except in two, he never remarked any nodes which could be regarded as unequivocally syphili- tic One of these yielded to blisters and sarsaparilla ; the other, after resisting guaia- cura and sudorifies, was dispersed by mer- cury (On Military Surgery , Ed. 2, p. 581.) Dr. Hcnnen’s statement on this subject would have been more satisfactory had it comprised his opinion of the characters of an unequivocally syphilitic node. On the whole, it appears tolerably certain that mercury, especially when employed unmer- cifully, and even when employed in mode- ration, and the patient exposes himself to damp and cold, tends to promote the fre- quency of nodes, as a sequel of the venereal disease, though as the long and abundant use of the same mineral does not cause the same consequence after other complaints, and venereal ulcers, treated altogether with- out mercury, rarely lead to nodes, it would seem as if these swellings were the product of the combined action of syphilis and mer- cury together. The infrequency of nodes in the strictly non-mercurial practice, is one of the most important facts yet esta- blished in its favour, and it is curious to find from some quotations made by Dr. Herinen, that it was well known in former days. Fallopius, in his 86th chap. De Ossium Cor- ruptione, speaking of the loss of the bones of the nose and palate, says “ et sciatis quod non in omrii iuveterato gallico hoc fit, sed tantum in illis, in quibus inunclio facta est cum hydrargyro And Fernelius, in speaking of the injurious effects of mer- cury, observes, “ recidiva raro similis est radici, neque iisdem symptomatis exercet, sed fere distillatione, arthritide tophis, vel ossium carie.” (Jlphrodisiacus. Vol.3,p 146.) And Palmarius, in considering the affection of the bones, as Dr. Hennen has noticed, uses the following remarkable words : u sed hoc ils duntaxat contingit, qui olim a lue venerea hydrargyrosi vindicati putareutur, non qui decocto guaiacino etalexipharmaco curati fuissent.” (De Morb. Contagiosis 9 Cap. 7, lib. 2, p. 124; Parisiis, 1578.) Dr. Hennen expresses his own conviction, in which I entirely agree, that the carious affections of the bones, which are so com- mon in persons treated by long mercurial courses, proceed not from the disease, but from the remedy rapidly and irregularly thrown in while periostitis exists ; and ho has not seen a single case of carious bone in the military hospitals, since the non- mercurial treatment was adopted, except where mercury has formerly been used. (On Military Surgery, Ed. 2, p. 505, 506.) Nor will the results of modern experi- ence and inquiries, made on a very expen- sive and impartial scale, allow us to consi- der the venereal disease as regularly and VENEREAL DISEASE. 020 unavoidably leading to any secondary symptoms, even though no medicine at all be employed for their prevention. This is fully exemplified in the official reports of the army hospitals. The particulars of 5000 cases, spoken of by Sir James M‘Grigor and Dr. Franklin, lead to the opinion, tint “the frequency or rarity of secondary symptoms wotrld seem 1o depend on circumstances not yet sufficiently understood or explained, although the following fact would tend to the belief, that either the constitutions of the men, or the mode of conducting the treat- ment without mercury, are the causes that possess the greatest influence in their pro- duction. In one regiment, 4 secondary cases out of 24, treated without mercury, su- pervened.” In another regiment, 68 cases were treated without mercury, all bearing marks of true venereal disease, (and 28 of them especially selected for their decided characters of chancre) yet no secondary symptoms of any kind had taken place fif- teen months after the treatment had ceased. The same document, founded on the above large number of cases, confirms another fact, that no peculiar secondary symptoms follow peculiar primary sores; a conclusion which is directly adverse to Mr. Carmi- chael’s opinions, of which I have taken more notice in another work. (See First Lines of the Practice of Surgery , Vol. 1, Ed. 4.) According to Mr. Hunter, the time neces- sary for the appearance or production of the local effects, in parts most susceptible of the disease, after the virus has passed into the constitution, is generally about six weeks ; but in many cases the period is much longer, while in other instances it is shorter. Sometimes the local effects make their appearance within a fortnight after the possibility of absorption. The effects on other parts of the body, which are less susceptible of the venereal irritation, or slower in their action, says Mr. Hunter, are much later in making their ap- pearance. And when the first and second order of parts are both contaminated, the effects generally do not begin to appear in the latter till after a considerable time, and sometimes not till those affecting the for- mer parts have been cured. Mr. Hunter, however, refers to instances in which the periosteum, or bone, was affected before any of the first order of parts ; but he was uncertain whether the skin or throat would afterward have become dis- eased, as the disorder was not allowed to go on. Venereal Eruptions. The whole tenor of Various facts, specified in the foregoing co- lumns, tends to prove, that what is usually called the venereal disease is in reality seve- ral diseases, modified also by constitution, climate, regimen, and mode of treatment. And hence,* perhaps, the chief source of all the perplexity and uncertainty, which are yet so manifest as fully to justify the doubt sometimes entertained, whether any dis- ease, corresponding to the former notions of syphilis, really exists. Were any proof" of the truth of this reflection needed, in addition to the many other proofs of it already premised, the subject of venereal eruptions would at once furnish it ; for here no kind of regularity can be traced, either in the appearances on the skin abstractedly considered, nor in the connexion between certain kinds of primary ulcers and particu- lar forms of cutaneous disease. Nay, as I have noticed in the preceding pages, some- times, in consequence of a primary vene- real sore, different kinds of eruptions form together, or successively on one individual; and, as far as one can judge by the eye, ex- actly the' same kind of chancre may produce very different breakings out in different per- sons, even though treated on precisely the same plan. These circumstances are truly confusing. In Mr. Rose’s paper, however, there is a partial confirmation of one part of Mr. Carmichael’s theory, viz. the fre- quency of papular eruptions after simple primary ulcers, or superficial sores, which readily heal. According to the latter gen- tleman, this form of eruption may also fol- low gonorrhoea, and is generally preceded by fever, and ends in desquamation. What- ever may be the degree of truth respecting the relation between this kind of eruption and the alleged primary complaints, the practice recommended by Mr. Carmichael for such cases is judicious. General blood- letting is recommended when there is fever, and the medicines praised are antimonials and sarsaparilla. Afterward, when the fever subsides, and the eruption desquamates, an alterative course of antimony and calomel, it is said, will accelerate the cure, though not absolutely necessary. In cases of vene- real pustular eruptions, supposed by Mr. Carmichael to be most frequent after chan- cres with elevated edges, '.vithout indura- tion, bloodletting is also advised during the febrile stage, followed by antimonials, sar- saparilla, guaiacum, tar-ointment, baths of sulphurated kali, or the nitro-muriatic bath ; and after the pustules have terminated in scaly blotches, alterative doses of mercury, conjoined with sarsaparilla or guaiacum. An eruptioq of tubercles, or spots of a pus- tular tendency, or of both intermixed, pre- ceded by fever, and terminating in ulcers covered with thick crusts, complaints which Mr. Carmichael considers a sequel rather of the phagedenic than other chancres, he treats at first by bloodletting, followed by antimonials, sarsaparilla, guaiacum, com- pound powder of ipecacuanha, arseniate of kali, nitrous acid, and nitro-muriatic bath. Mercury is said to be hurtful, except in the last stage. To scaly blotches, which he conceives to be a sequel of the true chan- cre, or callous ulcer, he applies the same local treatment as to pustular eruptions, and he deems the question, whether sarsaparilla and guaiacum might here be substituted for mercury, yet unsettled. (See Obs. on the Symptoms, tyc. of Venereal Diseases , Synop- sis, p. 205, fyc.) The investigations made in the military hospitals decidedly prove. venereal disease. that all kinds of eruptions, supposed to be venereal, may be cured without mercury ; but, I believe, the great and superior useful- ness of moderate quantities of mercury for the removal of the scaly, copper-coloured blotches, is still generally acknowledged. But, even in these cases of copper-coloured spots, Mr. Bacot’s advice may be good, viz. when the general health is much deranged, the tongue loaded and furred, and the appe- tite gone, to defer mercury “ until, by pro- per evacuations and attention to the gfeneral health,’' the patient has had the benefit of a delay, “ which will, in many instances, render all farther medical treatment unne- cessary. It is undoubtedly true that, what- ever plan be pursued, these eruptive symp- toms will eventually disappear ; still, where they continue to linger for a long time, and are attended with^ their usual accompani- ments of great languor, debility, and dis- turbed rest, I neither know, nor can I un- derstand, the advantage of delaying that remedy, which repeated experience has taught me to rely upon,” &c ( Bacot on Syphilis, p. 99.) Although Mr. Carmichael’s practice seems good, his theory, about the connexion of certain sores with particular eruptions, and other peculiar secondary symptoms, appears to be nearly refuted by the late investigations made in the military hospitals. To some facts, relating to this question, I have already adverted. There is as little certainty, about the essential characters of a syphilitic erup- tion, as about the test of every other symptom of the venereal disease, or, rather diseases. While Mr. Hunter describes the eruption as generally occurring over the whole body, Dr. Bateman states, that syphilitic affections of the skin com- monly make their first appearance on the face, where they are usually copious, and on the hands and wrists. ( Pract . Synopsis of Cutaneous Diseases, p. 332, edit. 3.) Their colour, he says, is in general less livid, than that of ordinary eruptions, being of a brown- ish red of different shades ; but that this is not universal ; for some of the syphilitic ecthymafa have a bright red base in the be- ginning. Exposure to cold accelerates their progress, and increases their extent ; while, on the other hand, warmth retards and meliorates them. (P. 333.) According to Hunter, the discolourations make the skin appear mottled, and many of the eruptions disappear, while others continue, and in- crease with the disease. In other cases, the eruption comes on in distinct blotches, which are often not ob- served, till the scurf has begun to form. At other times, the eruption assumes the appearance of small distinct inflammations, containing matter, and resembling pimples, not being however, so pyramidal, nor so red at the base. Mr. Hunter also observes, that venereal blotches, on their first, coming out, are often attended with inflammation, which gives them a degree of transparency, which is generally greater in the summer, than the winter, especially, if the patient be kept 02 1 warm. In a little time, this inflammation disappears, and the cuticle peels off in the form of a scurf. The latter occurrence often misleads the patient and the surgeon, who look upon this dying away of the in- flammation, as a decay of the disease, till a succession of scurfs undeceives them. The parts affected next begin to form a copper-coloured, dry, inelastic cuticle, call- ed a scurf, or scale. This is throw n off, and new ones are formed, which spread to the breadth of a sixpence or shilling ; but, sel- dom more extensively, at least, for a consi- derable time. In the mean while, every succeeding scale becomes thicker and thick- er, till at last it becomes a common scab. Then the disposition to the formation of matter takes place in the cuti^ underneath, and a true ulcer is produced, which com- monly spreads, although in a slow way. When the affected part of the skin is op- posed by another portion of skin, which keeps it in some degree more moist, as be- tween the nates, about the arms, between the scrotum and the thigh, in the angle be- tween the two thighs, on the red part of the lip, or in the arm-pits, the eruptions, instead of being attended with scurfs and scabs, are accompanied with an elevation of the skin, which is swollen with extravasated lymph into a white, soft, moist, flat surface, w r hich discharges a white matter. {Hunter.) Mr. Carlisle has pointed out what he terms an herpetic abrasion of the cuticle ori the breast, or abdomen, having the appear- ance of venereal blotches. He states, that it is less deep in the skin ; that it has less of an inflammatory base ; and that it is not so distinctly pircumscribed, as the true vene- real blotch. It never forms a purulent crust ; but is simply a furfuraceous scaling of the cuticle. This form of disease seems to him to be produced by a disordered stomach and liver. (See Loud. Med. Deposit. Vol. 7, p. 92.) A venereal eruption often attacks that part of the fingers, on which the nail is formed. Here, the disease renders that surface red, which is seen shining through the nail ; and if allowed to continue, a separation of the nail takes place. When surfaces of the bod} r , covered with hair, are attacked, the hair separates, and cannot be re-produced as long as the dis- ease lasts. It must be allowed, that it is frequently very difficult to say, whether an eruption is syphilitic or not, and an opinion should rather be formed from the history of the case, than from any particular appearance of the eruption itself. As Dr. Bateman has remarked, the cutaneous eruptions, which are the result of the venereal poison, are often the source of considerable embarrass- ment to the practitioner. They assume such a variety of forms, that they bid defi- ance to any arrangement founded upon their external character ; and in fact, they possess no common, or exclusive marks, by which their nature and origin are indicated. There is perhaps, no order of cutaneous appearan VENEREAL DISEASE. ces, and scarcely any genus, or species of tbe chronic eruptions, which these secon- dary symptoms of syphilis do not occasion- ally resemble. Dr. Bateman admits, how- ever, that in many cases, there is a differ- ence, which a practised eye will recognise, between the ordinary diseases of the skin and the syphilitic eruptions, to which the same generic appellation might be given. This, says he, is often observable in the shade of colour , in the situation occupied by the eruption, in the mode of its distribution , and in the general complexion of the patient. Hence, to a person conversant with those ordinary diseases, a degree of anomaly in these respects will immediately excite a sus- picion, which will lead him to investigate the history of the progress of such an erup- tion, and of its concomitant symptoms. (See Bateman's Practical Synopsis of Cuta- neous Diseases, p. 331, 332, Edit. 3.) Dr. Hennen in his valuable book, does not pretend to be able to discriminate the true syphilitic eruptions from others, and indeed, by what criterion they are to be known, I am myself entirely puzzled to comprehend, after the numerous facts, so fully established by recent experimental inquiries. Dr. Hennen generally approves of delaying mercury at first, in order to see whether these cutaneous affections will yield to other means ; “ but (says he) I should not very long postpone the employment of the mild- est mercurial alteratives, aided by warm bathing, and sudorifics. (On Military Sur- gery. Ed. 2, p. 518.) Venereal Disease of the Throat, Mouth, and Tongue . — In the throat, tonsils, and in- side of the mouth, the disease is said by Mr. Hunter generally to make its appearance at once in the form of an ulcer, without much previous tumefaction. Consequently the tonsils are not much enlarged. A venereal ulcer in the throat 'was suppo- sed by the same author to be in general tolerably well marked, though he confesses, that it may not in every instance be distin- guishable from an ulcer of a different na- ture. Several diseases of the throat, he re- marks, do not produce ulceration on the surface. One of these is common inflam- mation of the tonsils. The inflamed place often suppurates in the centre, so as to form an abscess, which bursts by a small opening ; but never looks like an ulcer that has begun superficially, like a true venereal sore. The case is always attended with too much in- flammation, pain, and tumefaction of the parts, to be venereal. Also when it suppu- rates and bursts, it subsides directly, and it is generally attended with other inflamma- tory symptoms in the constitution. Mr. Hunter then notices an indolent tu- mefaction of the tonsils, peculiar to many persons whose constitutions are disposed to scrofula. The complaint produces a thickness in the speech. Sometimes coagu- lable lymph is thrown out on the surface of the parts affected, and occasions appearan- ces, which ♦are by some called ulcers; by some sloughs; and, by others putrid sore- throats. The case is attended with too much swelling to be venereal, and with a little care, it may easily be distinguished from an ulcer, or loss of substance. How- ever, when this difference is not obvious at first sight, it is proper to endeavour to remove some of tbe lymph, and if the surface of the tonsil underneath should appear to be free from ulceration, we may conclude with certainty, that the disease is not venereal. Mr. Hunter states, that he has seen a chink filled with coagulable lymph, so as to appear very much like an ulcer; but on removing that substance, the tonsil underneath was found perfectly sound. He adds, that he has seen cases of a swelled tonsil, having a slough in its centre, which slough before its detachment, looked very like a foul ulcer. The stage of the com- plaint, he says, is even more puzzling when the slough has come out ; for then the dis- ease has most of the characters of the vene- real ulcer. Whenever he met with the dis- ease in its first stage, he always treated it as if it had been of the nature of erysipelas, or a carbuncle. When the complaint is in its second stage, without any preceding local symptoms, he recommends the prac- titioner to suspend his judgment, and to wait a little, in order to see how far nature is able to relieve herself. If there should have been any preceding fever, the case is still less likely to be venereal. Mr. Hunter informs us, that, he has seen a sore-throat of this kind mistaken for a venereal case, and mercury given till it affected the mouth, when the medicine brought on a mortifica- tion of all the parts concerned in the first disease. Another complaint of these parts, which Pdr. Hunter represents as being often taken for a venereal one, is an ulcerous excoria- tion, which runs along their surface, be- coming very broad and sometimes foul, having a regular termination, but never going deeply into the substance of the parts, as Mr. Hunter believes the venereal ulcer does. No part, of the inside of the mouth is exempt from this ulcerous excoriation ; but, according to Mr. Hunter, the disease most frequently occurs about the root of the uvula, and spreads forward along the palatum molle. He remarks, that the complaint is evidently not venereal, since it does not yield to mercury. He has seen these ulcerous excoriations continue for weeks, without undergoing any change, and a true venereal ulcer make its appearance on the surface, of the excoriated part. He says, that such excoriations were cured by bark, after the end of the mercurial course, by which the syphilitic sore was cured. This author describes the true venereal ulcer in the throat, as a fair loss of substance , part being dug out, as it were, from the body of the tonsil : it has a determinate edge, aiul is commonly very foul, having thick while matter, like a slough, adhering to it, and not admitting of being washed away. Here, however, as in most other supposed forms of syphilis, some test is wanting, by VENEREAL DISEASE. 023 which the case may be certainly distinguish- ed from other diseases of the throat, present- ing similar appearances ; for, as Mr. Rose has very truly remarked, “ the excavated ulcer of the tonsils, as described by Mr. Hunter, is not, as Mr. Carmichael seems to think, a peculiar symptom of the presence of the syphilitic virus. I have repeatedly seen it, as well as the scaly blotch, in cases where mercury had beeu freely employed for the primary sores, and in which I considered the virus as eradicated, and both have dis- appeared under the use of sarsaparilla.” (Med. Chir. Trans. Vol. 8 , p. 421.) In a re- cent work, Mr. Carmichael himself acknow- ledges the justice of the preceding observa- tion, and owns, that since the publication of his Essays, he has often noticed the exca- vated ulcer of the tonsils, either attending the primary phagedenic ulcer, or the train of constitutional symptoms which arise from it. ( On the Symptoms , <^c. of Venereal Diseases, P- 17.) In affections of the throat, Dr. Hen- nen states, that he “ w ould be more guarded than in any others, in the employment of mercury, until all inflammatory disposition was removed.” Afterward he has seen them yield, u as if by magic, so soon as the local effects of mercury on the parts within the mouth became obvious.” But when mercury was given earlier, he has seen a vast number of instances in which irremediable mischief was done. (On Military Surgery, Ed. 2, p. 518.) According to Hunter lues venerea some- times produces a thickening and hardening of the tongue, but frequently ulceration, as in other parts of the mouth. He describes venereal sores on the tongue, as generally more painful than those on the skin ; but less so than common sore throats from inflamed tonsils. They oblige the patient to speak thick, as if his tongue were too large for his mouth; with a sits all degree of snuffling. Mr. Hunter doubted the reality of a vene- real. ophthalmy, though he owns that there are inflammations of the eyes, which yield to mercury See the subject of iritis in the article Ophthalmy. Symptoms of the second stage of Lues Ve- nerea. — The periosteum, fascia, tendons, ligaments, and bones, are the parts which Mr. Hunter enumerates, as liable to be af- fected ir» the second stage of lues venerea. This observation in its full extent, however, seems to be rendered rather questionable ; for it would appear from the evidence both of ancient and modern writers, that true nodes , or venereal swellings of the bones, and particularly caries, rarely take place from syphilis, unless mercury be employed, it is an observation of Mr. Hunter’s, that we can- not always know with certainty what parts may become affected in this stage of the disease. He says he has known the dis- temper produce a total deafness, some- times followed by suppuration, and great pain in the ear, and side of the head. I have already explained, that it was one of this gentleman’s doctrines, that the second order of parts were generally deep-seated. When these become irritated by the poison, he observes that the progress of the disease is more gradual, than in the first order of parts. It assumes very much the character of scrofulous swellings, or chronic rheuma- tism ; only it affects the joints less frequently than the latter affection does. A swelling sometimes makes its appearance on a bone, when there has been no possible means of catching the infection for many months ; and in consequence of the little pain expe- rienced, the tumour rflay be of some consi- derable size, before it is noticed. Some- times a great deal of pain is felt ; but no swelling comes on, till after a long while. According to Mr. Hunter, these remarks are also applicable to swellings of the tendons, and fasciae. As tumours of this kind only increase by slow degrees, they are not at- tended with symptoms of much inflamma- tion. When they attack the periosteum, they seem like an enlargement of the bone itself, in consequence of being very firm, and closely connected with the latter part. Mr. Hunter also further observes, that in these advanced stages of the disease, the inflammation can hardly gel beyond the adhesive kind, in which state, it contiuues to become worse and worse, and when matter is formed, it is not true pus, but of a slimy description. Some nodes, be says, both of the tendons and bones, last for years, before they form any matter at all. These cases, he considered, as not being certainly venereal, though commonly consi- dered as such. Mr. Hunter found it difficult to explain the reason why, when lues venerea attacks the bones, or the periosteum, the pain should sometimes be very considerable, and sometimes very trivial. Venereal pains in fhe bones Bre described by Mr. Hunter as being of a periodical kind, generally most severe in the night-time. At the present day, when many cases formerly supposed to be syphilitic, are treated without any mercury, and even those which are reputed to be venereal, are cured by much smaller doses of that medi- cine than were given in Mr. Hunter’s time, nodes have become much less frequent, and I have already in a previous part ot this article expressed my decided belief in the justness of the opinion given by Fallopius and others, that a disposition to nodes is often occasioned by the abuse of mercury. Treatment of Lues Venerea.— In Mr. Hun- ter’s opinion, the first order of parts, or (hose which are most suscept ible of being affected in lues venerea, are also the most easy of cure ; while the second order of parts take more time to be remedied. In the class of complaints, arising in the second stage of the lues venerea, Mr. Hun- ter believed, that it was unnecessary to con- tinue the employment of mercury, till all the swelling had disappeared. For it is ob- served by this distinguished writer, that since these local complaints cannot conta- minate the constitution by re-absorption, and since the venereal disposition and action from the constitution can be cured, while VENEREAL DISEASE. B24 the local effects still remain, and this even when the tumefaction, forming nodes on the bones, fasciae, kc. has proceeded to sup- puration, there can be no occasion for con- tinuing the course, after the venereal action has been destroyed. Whatever may be hereafter decided concerning the superiority of mercury as a remedy for many seconda- ry symptoms, one thing appears already well made out, viz. that it should always be employed with moderation, lest it produce worse effects, and moYe terrible diseases, than those which it is designed to relieve. For an account of the various ways of exhi- biting it, I must refer to the article Mercury. To the following ingenious reasoning on the operation of mercury, and the principles by which its administration should be regula- ted, surgeons of the present day will not give more credit than facts warrant, because some of Mr. Hunter’s opinions are manifestly in- fluenced by the supposition, that mercury is absolutely necessary for the cure of the ve- nereal disease. In curing the lues venerea, mercury can only have two modes of action ; one on the poison : the other on the constitution. If, says Mr. Hunter, mercury acted on the poi- son only one might conceive it did so, either by destroying its qualities, by decom- posing it, or else by attracting it and carrying it out of the circulation. If mercury acted in the first of these ways, one would expect, that the cure would depend on the quantity of the medicine taken into the system. If it acted in the second manner, one would Infer, that the progress of the cure would be proportionate to the quantity of evacu- ation. But, observes Mr. Hunter, if it act upon the principle of destroying the diseased action of the living parts, and of counteract- ing the venereal irritation, by producing one of a different kind, then, neither quantity alone, nor evacuations, will avail much. He states, that the quickness of the cure depends on quantity, joined with visible effects. However, it is added, that although the ef- fects which mercury has upon the venereal disease, are in some degree proponioned to the local effects of the medicine on some o t the glands, or particular parts of the body, as the mouth, skin, kidneys, and inte. lines, yet such effects are not altogether propor- tioned to these other circumstances. When mercury disagrees with the constitution, so as to produce great irritability and hectic symptoms, this action of irritation, as Mr. Hunter explains, is not a counter-irritation to the venereal disease. It was also noticed by the same author, that the effects of mercury on lues venerea are always in proportion to the quantity of the remedy exhibited in a given lime, and the susceptibility of the constitution to the mer- curial irritation. He says that these circum- stances require the most minute attention, and that, in order to obtain the greatest ac- tion of mercury with safety, and in the most effectual manner, the medicine must be given till it produces effects somewhere. However, it must not be exhibited too quickly, in order that a sufficient quantity may be given, before we are obliged to stop, in consequence of the effects. Mr. Hunter thinks, that when the local effects are pro- duced too quickly, they prevent a sufficient quantity of the remedy from being taken into the system to counteract the venereal irrita- tion at large. Mr. Hunter mentions his having seen some cases, in which mercury acted very readily locally, and yet the constitution was hardly affected by it, for the disease would not give way. He states, that he has met with other cases, in which the mere quantity of mercury did not answer, till it was given so quickly as to affect the constitution in such a manner as to produce local irritation, and, conse- quently, sensible evacuations. This, be ob- serves, is a proof that the local affects of mercury are often the sign of its specific effects on the constitution at large, and it shows that the susceptibility of the diseased parts to be affected by the medicine, is in proportion to its effects on the mouth. Its effects, he contends, are not to be imputed to evacuation; but to its irritation. Hence, he inculcates, that mercury should be given, if possible, in such a manner as to produce sensible effects upon some parts of the body, and in the largest quantity that can be given, to produce these effects within cer- tain bounds. Mr. Hunter also remarks, that these sensible effects should be the means of determining how far the medicine maybe pushed, so as to have the greatest effect on the disease, without endangering ihe consti- tution. The practice must vary according to circumstances ; and if the disease is in a violent degree, less regard must be had to the constitution, and mercury must be thrown into the system in larger quantities ; a very dangerous precept, as far as 1 can judge, from many cases in which I have seen it acted upon. Mr. Hunter likewise acquaints us, that when the disease is in the first order of parts, a smaller quantity of mercury is necessary, than when the second order of parts are affected, and the disease has been oi long standing, its first appearances alone being cured, and the venereal disposition still re- maining in the secondary parts. For the purpose of curing the venereal disease, whether in the form of chancre, bubo, or lues venerea, Mr. Hunter was of 'opinion, that probably the same quantity of mercury is necessary. He represents, that one sore requires as much mercury as fifty sores in the same person, and a small sore as much ns a large one He thought that the only difference, if there is any, must depend upon th** nature of the parts affected, that is, on. their being naturally active or in- dolent. He conceived, however, that on the whole, recent venereal complaints are gene- rally more difficult ol cure, than the symp- tom? of lues venerea, and that this may make a difference, in regard to the quantity of mercurv necessary. Havingnow delivered the principal gene- ral instructions, relative to the exhibition ot VENEREAL DISEASE. 62 o mercury in the treatment of the venerea! disease, as given by Mr. Hunter, I must not quit this subject without remarking, that even this eminent surgeon appears on the whole too partial to the long use of mercu- ry, and sometimes to the introduction of immoderate quantities of it into the system. In general, however, his observations tend to condemn all violent salivations. It is to be recollected, that in his days, nobody had a suspicion that truly syphilitic sores (if this expression be allowable, while they cannot be defined, nor distinguished by their ap- pearances) would in the end spontaneously heal, and he himself had no dependence upon any medicine, except mercury, for the cure of the true venereal disease. But mo- dern experience evinces, that the disorder seldom now presents itself in forms so bad and intractable as formerly ; that it is even capable of spontaneously ceasing ; and that Ave hardly ever see cases in which it is re- quisite to give mercury, except in very moderate quantities. Indeed, such is the change, that many surgeons suspect that the very nature of the disease must have under- gone a material alteration or modification. In England, in rny opinion, every thing is to be referred to the improved manner of employing mercury only in moderate doses, and never pushing its exhibition, till the constitution is so impaired, that undescriba- ble forms of diseases ensue, which are sometimes the compound effect of mercury and syphilis together ; and, in other in- stances of that description, which surgeons now frequently call syphiloid , or pseudo- syphilitic , not depending upon the venereal poison at all, but upon a state of the system, which mercury is known to aggravate in the Avorst degree. For additional informa- tion concerning internal remedies for the venereal disease, see Mercury, Guaiacum, Mezereon, Muriatic Acid , Nitrous Acid , Sar- saparilla, Sulphuric Acid, fyc. With respect to the local treatment of the symptoms of lues venerea, Mr. Hunter thought that none would in general be ne- cessary, since the constitutional treatment Avould commonly effect a cure. However, he admits, that sometimes the local effects will not give way, and the parts remain swollen in an indolent inactive state, even after there is every reason to believe that the constitution is perfectly cured. In such cases, he recommends assisting the consti- tutional treatmeat by local applications of mercury to the part, either in the form of a plaster or ointment. The latter applica- tion, he says, is the best. When these are not sufficient, he advises an attempt to he made to excite inflammation of another kind. He says he has seen a venereal node, which gave excruciating pain, cured by mere- ly making an incision down to the bone, the whole length of the node. The pain ceased , the swelling decreased, and the sore healed up kindly, without the assistance of a grain of mercury. He mentions, that blisters have been applied to nodes with success, remo- ving the pain, end taking away the swelling. Von. !!. TO With regard to these last cases I may add, that, for many years past, the idea of com- pletely dispersing nodes by mercury has been entirely abandoned in St. Bartholo- mew’s hospital. In this institution, long protracted mercurial courses for the cure of such swellings are totally relinquished. When small moderate quantities of mercury have had their full effect, a blister is ap- plied o\ T er the swelling, and kept open, under which plan the tumour generally sub- sides as far as its nature will allow. Diseases resembling the Venereal. Pseudo- syphilis. — Sores on the glans penis, prepuce, &,c. in the form of chancres, as Mr. Hunter notices, may and do arise without any vene- real infection, and sometimes they are a consequence of former venereal sores, Avhich have been cured. The symptoms, produced by the \ r enereal poison in the constitution, sire such as are common to many other diseases. For in- stance, Mr. Hunter remarks, that blotches on the skin are common to what is called a scorbutic habit ; pains are common to rheu- matism ; swellings of the bones, perios- teum, fasciae, &c. to many bad habits, perhaps, of the scrofulous and rheumatic kind. Thus, says he, most of the symptoms of the venereal disease, in all its forms, are to be found in many other diseases. Hence , the original cause, and many leading circum- stances , such as dates, effects of the disorder upon others, from connexion, when only local , the previous and present symptoms, fyc. must be considered, before we can determine abso- lutely what the disease truly is. All the cir- cumstances and symptoms, taken together, may be such as will attend no other disease. However, Mr. Hunter confesses, that with all our knowledge, and with all the appli- cation of that knowledge to suspicious symptoms of this disease, we are often mis- taken, calling distempers venereal , which arc. not so, and sometimes supposing really syphi- litic affections to be of another nature. Mr. Hunter takes notice, that in some constitutions, rheumatism, in many of its symptoms, resembles the lues venerea. The nocturnal pains, swelling of the ten- dons, ligaments, and periosteum, and pain in those swellings, are symptoms both of the rheumatism, and also of the venereal disease, when it attacks such parts. Mr. Hunter, however, did not know that he had ever seen the lues venerea attack the joints , though many rheumatic complaints of such parts are cured by mercury, and therefore supposed to be venereal. Mercury, given Avithout caution, often produces the same symptoms as rheuma- tism. Such complaints Mr. Hunter had seen mistaken for venereal ones, and mer- cury continued. He explains, that some diseases not only resemble the venereal iri appearance, but in the mode of contamina- tion, proving themselves to be poisons by affecting the part of contact ; then produ- cing immediate consequences similar to buboes ; and also remote consequences si- milar to the lues venerea. VENEREAL DISEASE <>■20 Mr. Hunter observes, that it is nearly as dangerous, in some constitutions, to give mercury, when the disease is not venereal, as to omit it in other cases, which are really syphilitic; and had he been ac- quainted with recent investigations, he would undoubtedly have gone further, and declared that it is in reality far more dan- gerous. Many of the constitutions, which put on some of the venereal symptoms, when the disease is not really present, he says, are those with which mercury seldom agrees, and commonly does harm. He had seen mercury, which was exhibited for a supposed Venereal ulcer of the tonsils, pro- duce a mortification of those glands, and the patient was nearly destroyed. Mr. Abernetby, in his Surgical Observa- tions, 1804, has treated at some length of diseases resembling syphilis, and has ad- duced several very interesting cases, which i advise every surgical practitioner to read with the greatest attention, as in fact they confirm the views of the subject lately so fully established. “ A gentleman (says he) thought that he had infected a slight cut on his hand (which was situated in front of, and just below the little finger,) with the discharge from a bubo in the groin, that he had occa- sion to open. The wound fretted out into a sore about the size of a sixpence, which he showed me, and which 1 affirmed had not the thickened edge and base, and other characters of a venereal chancre. 1 there- fore recommended him to try the effect of local means, and not to use mercury. “ In about a month, the sore, which had spread a little, became again contracted in its dimensions, and assumed an healing ap- pearance. At this time pain was felt ex- tending up the arm, and suddenly a consi- derable tumour arose over the absorbing vessels, which proceed along the inner edge of the biceps muscle. This tumour became nearly as big as a small orange. As the original sore seemed now disposed to heal, and as there was no surrounding indura- tion, I could not believe it venereal, and therefore recommended him still to abstain from mercury, and apply leeches and linen moistened in the aq. litbarg. acet. comp, to the tumour formed over the inflamed ab- sorbents. For it seemed to me, that if the venereal poison had been imbibed from the sore, it would have passed on to one of the axillary glands, and would have caused in- duration and inflammation to take place there more slowly than had occurred on the present occasion. “ Under this treatment the tumour was discussed, and the sore at the same time healed. About three weeks afterward, the patient called on ine, and said that there were venereal ulcers in his throat; and in each tonsil there was an ulcer deeply exca- vated, with irregular edges, and with a sur- face covered by adhering matter ; ulcers, in short, which every surgeon, who de- pends on his sight as his guide, would have pronounced to be venereal. Shortly after also some copper-coloured eruptions aj> peared on his face and breast. He*showed his diseases to several surgeons, on whose opinion he relied, who, without hesitation, affirmed that they were venereal, and that the mercurial course had been improperly delayed. “ While the patient was looking out for lodgings, in order that he might go through the mercurial process, a circumscribed thickening and elevation of the pericra- nium, covering the frontal bone, appeared ; it was of the circumference of a half-crown piece ; and was, in short, what every sur- geon, who. is guided only by his sight and touch, would, without hesitation, have called a fair corona veneris. I now told the patient that I was more inclined to be- lieve his disease was not syphilitic, from the sudden and simultaneous occurrence of this node, with the sore throat, &.c. Other surgeons thought differently ; and I believe this very sensible and amiable young roan imagined that his health would become a sacrifice, if he any longer attended to my opinion. He was preparing to submit fo a mercurial course, when very important concerns called him instantly into the country. He went with great reluctance, taking with him mercurial ointment, &tc. ; and after a fortnight, I received a letter from him, saying that he found his com- plaints benefited by his journey, that busi- ness had prevented him from beginning the use of mercury for a few days ; that he now found it was unnecessary, for his symptoms had almost disappeared ; and shortly after- ward he became perfectly well.” Mr. Abernethy considers this case as the most unequivocal instance extant of a dis- ease occurring, which could not from ap- pearance be distinguished by surgeons of the greatest experience from syphilis, and which, however, was undoubtedly of a different nature ; (that is to say, it was of a different nature, according to certain cri- teria, then generally believed, but which recent investigations have proved to be destitute qf foundation.) All the tests here alluded to having been spoken of in the foregoing columns, I shall not here repeat them. Some years ago the nitric acid was intro- duced as a remedy for syphilis. (See Ni- trous Jicid.) To the position of its efficacy being as great in venereal cases as was first alleged, many surgeons have not acceded, though, as a sensible writer has observed, it has certainly been allowed, with some other medicines, to remain in a kind of copartnership with mercury, and admitted to be useful in venereal cases under certain circumstances. A great deal of this want of agreement, on the effects of remedies in syphilitic cases, is now explained by the imperfection of the diagnosis, and the im- portant fact, that the disease may generally be cured iu lime, without any medicines whatsoever, though this time is sometimes long. Dr. Scott, who first suggested the use of nitrous acid, has attempted to Recount VENEREAL DISEASE 627 for its alleged occasional failures, by ob- serving that the acid, which he employed, was not pure nitric acid, but an impure acid, containing an admixture of muriatic acid. He therefore, some time ago, re- commended the use of a compound acid, containing three parts of nitric acid, and one of muriatic, which he administered inter- nally, and also applied externally, largely diluted, as a bath, until the gums were af- fected and ptyalism pVoduced ; and he con- ceived every trial as quite inconclusive, unless these constitutional effects occurred. “ The acid that I have used of late (says Dr. Scott) is the nitro muriatic ; and it is formed by mixing together equal parts of the nitrous, or nitric acid, and muriatic acid. If these acids be in the state of concentra- tion, that they usually possess in the shops, and if the quantities be considerable, a great volume of gas is evolved on their coming into contact, which taints every part of a house, is extremely hurtful to the lungs, and disagreeable to the smell. To avoid this inconvenience, I put a quantity of water, at least equal in bulk to both the acids, into a bottle, and I add the acids to it separately. This method does not only prevent the unpleasant odour, but it tends to retain the chlorine, on which its effects depend, it is well known, that the nitro- muriatic acid acts very readily on the metals and earth ; nothing therefore but glass, or extremely well glazed vessels of porcelain, should be used to contain it. Wooden tubs for bathing answer very well, and they should always be made as small as ; possible , compatible with their holding the body, or the limbs that we wish to expose to the bath. From their being small, we save acid, and are able to heat the bath with ease. In India, I have often exposed the whole body below the head to this bath ; but here I have been satisfied, in general, with keeping the legs and feet exposed to it. In order to warm the bath, after the first time, I have commonly made a third or a fourth part of it to be thrown away, and the loss replaced by boiling water and a proportional quantity of acid. To save the expenditure of acid, I have occasionally warmed a portion of the bath in porcelain vessels, placed near the fire, but l fear this may diminish its effects. u It is no easy matter (continues Dr. Scott,) to give directions, with regard to the degree of acidity of the bath. I have commonly made it about as strong as very weak vinegar, trusting to the taste alone. The strength should be regulated by the degree of irritability of the patient’s skin. 1 may say, that although I like to know that it is strong enough to prick the skin a very little, after being exposed to it from fifteen to thirty minutes, yet I believe that even such an effect as this is unnecessary. 1 ‘ The time too of remaining in the bath, in order to produce the greatest effect, is a matter of doubt. I have kept the legs and feet exposed to it for half an hour or more ; but, with more delicate people, not above one-half, or one-third of that time. I have repeated these baths daily, or even twice, or thrice a day. (See Med. Chir. Trans. Vol. S, p. 181.) Dr. Scott adds, that the mere sponging the skin with nitro-muriatio acid, sufficiently diluted witli water, gives rise to the very same effects f.s bathing? and is more easily adopted. Fifteen or twenty minutes may be employed in the sponging, though a much less time produces very ma- terial effects. Dr. Scott has found the nitro-muriatic acid particularly useful, even in this coun- try, in that description of syphilis, which is termed pseudo-syphilis ; and he attributes the beneficial effects to the chlorine, which is loosely combined in this compound. (See Journal of Science and the Arts, Vol. 1, p. 205 — 211. Lond. Med. Reposil. Vol. 7, p. 59 ; and Med. and Chir. Trans., Vol. 8, p. 173, et seq.) The only important conclusion which l venture to draw from Dr. Scott’s observa- tions, is a confirmation of the fact of the generally curable nature of syphilitic dis- eases, without the aid of mercury. And I further believe, that though the nitro-muri- atie bath may sometimes be useful, the surest way of bringing it into discredit is to represent it as applicable to all forms of syphilis, for which neither this remedy, nor even mercury itself, will ever suffice. J. de Vigo, De Arte Chirurgica, fol. Lugd. 1518. N. Montesaurus . De Disposition^ us, quas vulgo Mai Fransos appellant, 1497. Ki- col. Massa de Morbo Gallico, Liber, 4lo. Te- net. 1532, et 1536, auctior, 1563. Nic. Lco- nicerus Liber de Epidemia quam ltali morurm Gallicum, Galli ero Xeapolitanum vacant, Fol. Papice . 1506. Gabr. Fallopius, de Tor- bo Gallieof^to. Patav. 1563. Kic.de Blegny, Zodiacus Medico- Gallicus, 4to. Geneves, 1680. Hieron. Fracaslorius, Syphilis Poema; et, Tractatus de: Syphilide ; Veronce., 1530. Also, De Contagionc et Contagiosis Morbis, Venet. 1546, Casp. Torella, Tractatus cum Consiliis contra Pudendagram, Romes, 1497. Also , Dialogus de Dolore et de Ulceribus in Pu- dendagra ; Romes, 1500. Ant. Francantia - nus, de Morbo Gallico, 8 to. Patav. 1563. Jul. Palmarius , De Morbis Contagiosis, 4 io. Paris , 1578. Guil. Rondeletius, de Morbo Gallico, 1576. J. Fernelius, Universa Me- dicina, 4 to. Venet. 1564, p. 584, 593, Ulric de Hulten, de Morbo Gallico . Mogun! 1531. R. Rostinio, Trattato di Mai. Fran - cess, \2mo. Venet, 1556. Al. Luisinus, Aphro- disiacus, Venet. 1566, et in 2 Tom. fol. Lugd. Bat. 1728, one of the most valuable collections of the Works of ancient writers on Syphilis. Diaz de Isla, Tratado contra las Bubas. 1527. Wm. Clowes, a new and approved Treatise , concerning the Cure of^the French Poclces, by the Unctions, 8va. Lond. 1575 ; said to be the earliest English book on Syphilis. J. Aslruc, de Morbis Venereis ; Lutet. Paris , 1740. Le Blond, (Jbs. sur la Fitvre Jaunt, Chap. 4. Leo Africanus, Descriptio A f rices, L. 1 , p. 86. The last two authors mention: the fad of the nature of the Venereal Di&af j If get wet! spontaneously in hot climates. I?r. Ah,- VENEREAL DISEASE. 62S cromby , Tula or. effienx Luis Venerece , scepe absque. Mercurio, ac ( semper absque Saliva- Hone Mercurial! Ciirandw Methodus, Land. \2rno. 1084. J. Sinteiaer, The Scourge of Venus and Mercury , represenled in a Treatise an the Venereal Disease, giving a succinct Ac- count of that Dreadful Distemper, and the fatal Consequences arising from mercurial Cures , 35 Account of a Successful Method of Treating Diseases of the Spine ; Sro. Bristol , 1813. 11. Earle , in Edinb . Med. and Surg. Jo urn. for January , 1815. J. L. Chbulant , Decas Pelvium Spinarumquc Deformatarum ; 4/o. 1818. G. Malseh, de nova Machina Graefiana Distortiones Spince Dorsi ad Sanan- das, necnon Disquisitio DeformHatum ista- rum ; 4to. Berol. 1818. Abercrombie , in Edinb . Med. and Surg. JournJ for January , 1818. Kapeler,iu Annuaire Mcd.Ckir. dcs Hdpitaux de Paris, T. i , p. 390 ; 4 to. Paris, 3819. T. Copeland, Obs. on the Symptoms and Treatment of Diseased Spine ; Svo. B. C. Brodie, Pathological and Surgical Observa- tions on the Joints p. 257, fyc. Svo. Bond. 1818. James Wilson , Lectures on the Struc- ture and Physiology of the Skeleton, and on the Diseases of the Bones and Joints ; p. 395, 8 vo. Bond. 1820. VINEGAR. (Sec Acetic Acid.) ^ VINUM 0111. Take of extract of opium ^i, cinnamon bark bruised, cloves bruised, of each 3j ; wine a pint. Macerate for eight days, and filter. The thebaic tincture, or liquid laudanum of Sydenham, in sur- gery, it is often preferred to the common tincture of opium, as an application to tiie eye. VIPER, BITE OF. See Wounds. VOLVULUS, (from voivo. to roll up.'* See Intussusception. w. ~Wf ART. Mr. Hunter observes, that a V ▼ wart appears to be an excrescence from the cutis, or a tumour formed upon it, by which means it becomes covered with a cuticle, which is either strong and hard, or thin and soft ; just as the cuticle is which covers the parts, from which the excres- cence arises. Warts are radiated from their basis to their circumference. The surface of the radii appears to be pointed, or granu- lated, like the surface of healthy granula- tions, with the exception of being harder, and rising higher. The surface on which the wart is formed, seems only to be capa- ble of producing one; for the surrounding and connecting surface does not throw out a similar substance. Thus, when a wart has once begun to grow, it rises higher and higher, without becoming larger at its basis. Such excrescences seem to have within themselves the power of growing ; for, as Hunter remarks, after they have risen above the surface of the skin, on which their basis cannot grow larger, they swell out into a round thick substance, which becomes rougher and rougher. In consequence of this structure, warts are very liable to be hurt by bodies rubbing against them, and from such a cause, they often bleed very profusely, and are rendered, sore and painful. (On the Venereal Disease, p. 250, Edit. 2.) As warts are adventitious substances, and not any part of the original structure of the body, their powers of life are weak. Hence when stimulated, they generally become smaller, and at length altogether disappear, or drop off. On this principle, warts may frequently be cured by the application of the sulphate of copper, or a powder, composed of the powders of savine leaves, and the subace- tate of copper, in equal proportions. However, the employment of stronger escharotics, like the nitrate of silver, or the concentrated acetic acid ; the removal of such excrescences with a knife, or pair of scissors; or tying their necks with a liga- ture, is a mode frequently preferred, be- cause the cure is sooner accomplished. The two last methods are eligible, when the wart has a narrow neck; but after the removal of the excrescence, it is still proper to touch the root with the caustic, or the acetic acid; for unless the whole be com- pletely destroyed, the wart will inevitably grow again. Warts on the pudenda, and about the anus, scarcely ever withstand the effect of the powder of savine, and subacetate of copper, though they will sometimes resist a course of mercury, adequate to cure lues venerea ; a consideration, which led Mr. Hunter to believe them not to be syphilitic. In this opinion, I believe all the best sur- geons of the present day concur.* WHITLOW. ( Panaris , Onychia, Pana- ritium, Paronychia.) A whitlow is an in- flammation, about the end of the finger, exceedingly painful, and very much disposed to suppurate. The toes are also sometimes the seat of the disease. Writers usually divide Whitlows into four kinds. In the first, or mildest, a vesicle, filled with matter, commonly arises near the root, or side of the nail, after a superficial inflammation of trivial extent. The matter is situated immediately under the cuticle. Sometimes the abscess takes place under the nail, in which case, the pain is severe, and not unfrequently shoots upward, as far as the external condyle. * The ligature is as effectual and convenient as any method recommended, for the removal of warts. But as warts have seldom necks sufficient to retain the thread, I have been in the habit of resorting to a plan which 1 have always found successful, to the entire removal of warts. Take a fine sewing needle, armed with strong silk, and pass it through, the centre of the tumour at its base, taking care to go deep enough, that the whole disease may be included, then by tying this at each side, of sufficient tightness to interrupt the cir- culation, the wart will dropoff within the w'eek, without inconvenience to the patient. From the manner in which the ligatures are applied, there is no possibility of their coming off, until the disease come with it. In this way, I have freed a hand from a dozen at one time, to the great satisfaction of the individual ; and when removed in this manner, I have never found them recur- Am. Ed. 636 WHITLOW The second kind of whitlow is chieGy situ- ated in the cellular substance under the cutis, and, for the most part, occurs at the very end of the finger. In this sort of case, the inflammatory symptoms, especially the pain, are far more violent than in other common inflammations of net greater extent. However, although the pain is thus severe, it does not in general extend far from the part affected. Writers usually impute the violence of the pain, and the considerable degree of inflammation attending the com- plaint, to the hard and unyielding nature of the skin on the finger. To the same cause they also ascribe the difficulty of perceiving any fluctuation after matter is formed ; and the slowness with which the pus makes its Way outward. The third kind of whitlow is distinguish- able from the others by the following cir- cumstances. With the most excruciating pain, there is very little swelling in the affected finger, but a vast deal in the hand, particularly about the wrist, and over the whole fore-arm. The pain extends to the hand, wrist, elbow, and even the shoulder. When suppuration takes place, a fluctuation can never be felt in the finger, though it may very often be distinctly perceived in the hand, at the wrist, or even somewhere in the fore-nrrn. The case is frequently ac- companied with considerable fever. The disease is seated in the tendons and their sheaths, and the power of moving the fin- gers, and even the whole hand, is lost. Authors describe the fourth kind of whit- low as arising principally from an inflamma- tion of the periosteum. The case is attend- ed with one peculiarity, which is, that, how- ever violent the pain may be, it never ex- tends to the hand and fore-arm, nor is there any external swelling of the affected finger. Suppuration generally follows very soon, the usual consequence of which is a caries, or rather a necrosis, of the subjacent finger-bones. Whitlows commonly begin on the inside of the fingers ; but they do occasionally Commence on the back of these parts, and even on that of the hand. Though pain about the wrist is usually the effect of in- flammation in the finger, Acrel mentions a case in which the disorder was altogether confined to the hand itself. ( Vorfalle , 2 B. p. 191.) Mr. Wardrop has favoured the public with an account of a particular species of whitlow, which, from its malignant cha- racter, he has denominated the onychia ma- ligna. “The commencement of this dis- ease is marked by a degree of swelling, of a deep red colour, in the soft parts at the root of the nail. An oozing of a thin ichor afterward takes place at the cleft formed between the root of the nail and soft parts, and at last the soft parts begin to ulcerate. The ulcer appears on the circular edge of the soft parts at the root of the nail ; it is ac- companied with a good deal of swelling, and the skin, particularly that adjacent to the nicer, ha® a deep purple colour. The appearance of the ulcer is very unhealthy, the edges being thin and acute, and its sur- face covered with a dull yellow, or brown- coloured lymph, 'and attended with au ichor- ous and very fetid discharge. The growth ol the nail is interrupted, and loses its na- tural colour, and at some places appears to have but little connexion with the soft parts. In this state (says Mr. Wardrop) l have seen the disease continue for several years, so that the toe, or finger, became a deform- ed bulbous mass. The pain is sometimes very acute ; but the disease is more com- monly indolent, and accompanied with lit- tle uneasiness. The disease affects both the toes and the fingers. I have only observed it on the great toe, and more frequently on the thumb, than any of the fingers. It occurs, too, chiefly in young people •, but I have also seen adults affected with it.” (IVar- drop , in Med. Chir. Trans. Vol. 5, />. 135, 136.) The causes of whitlows are generally of a local nature. Writers enumerate the fol- lowing as the most common : a contusion ; suddenly warming the finger when it is ex- ceedingly cold ; pricks with needles, . or other sharp instruments ; and the insinua- tion of irritating matter into scratches on the finger. A surgeon, in operating lor a fistula in ano, has been known to cut his finger, and have, in consequence of the accident, a very severe and dangerous kind of whit- low. Richter also mentions a person who had a most obstinate whitlow, in conse- quence of a slight wound on the finger, in examining the head of a horse that had the glanders. Sometimes the cause of a whit- low depends on a splinter, or thorn, which continues lodged in the part. Very often, no particular cause whatever can he assign- ed for the complaint. The first case, which occurs about the root of the n§il, ought to be opened as soon as possible. When this plan is not adopted, the matter is apt to penetrate more deeply, reach the root of the nail, and occa- sion a loss of this part. When an effectual opening is not made, the matter collects again. In general, a detachment of the cu- ticle takes place as far as the abscess extends. When the inflammation has been very vio- lent, and the matter has made its way as far as the root of the nail, the nail itself is in general gradually detached, while the denu- ded portion of the root of the nail acts on the sore as a foreign body, and hinders it from healing. Hence the surgeon should repeatedly cut away as much of the lower edge of the nail as he can, and insinuate a little soft lint between the margin of the nail and the sore, in order to keep the latter from being irritated by the former. In pro- portion as the old nail gradually separates, a new one makes its appearance. When matter lies under the nail, an open- ing should be made through the part as speedily us possible, for the discharge of the abscess. In order to perform this operation, Richter advises the surgeon to scrape the naj! with a piece of glass, till it is as thin ns whitlow. 637 a can well be, when it may be cut through with a bistoury. In the secoml species of whitlow, suppu- ration may sometimes be prevented, and the inflammation be resolved, by the timely employment of proper means. When the pain is violent, and acute fever prevails, it may be adviseable to bleed the patient. In a few severe cases, the application of three or four leeches to the affected finger has been known to procure prompt relief. ( Schmucker .) Theden thinks, that applying a roller round the finger, hand, and arm, and frequently wetting the first two parts with a lotion, the most certain means of resolving the inflammation. Platner advi- ses the finger to be for some time immersed in water as warm as the patient can bear. Some recommend the external use of cam- phorated spirit, or the volatile alkali : while others advise the affected finger to be plun- ged in a warm solution of soap, or kali. When the whitlow is occasioned by a prick, particular care must be taken that no extra- neous substance remain in the puncture. When the symptoms do not lessen by the fourth day, Richter recommends an open- ing to be made. Even when no fluctuation is discovered, he approves of making a cru- cial incision in the seat of the pain, and he states, that although no matter may be dis- charged, the patient always derives infinite relief from the operation. The benefit, he says, may either be imputed to the bleeding, or to the division of the hard tense skin which compresses the subjacent inflamed parts. Sometimes the collection of matter can be plainly felt, and, in this case, there can be no hesitation about the place where the opening should be made. However, it may lie proper to remark, that the opening should always be made sufficiently large. When the surgeon makes a small puncture, it soon closes again, and a repetition of the operation become^ necessary. When open- ing the abscess is delayed, the theca of the flexor tendons easily becomes affected, or the matter may spread to a considerable exr tent under the skin. Sometimes it makes its way through the cutis by ulceration, and raises up the cuticle. In this case, as soon as the cuticle has been opened, a director should he introduced into the aperture in the skin, and the latter opening be enlarged with a bistoury. The third species of whitlow seldom affects the last phalanx of the fingers; but, generally, the second or third. In this case, Richter enjoins us never to defer making an opening longer than the third day. If we wait till suppuration happens, we shall wait till the tendons are destroyed, and the use of the finger lost. In the case under consi- deration, the matter is always of bad qua- lity, and very small in quantity. A fluctua- tion in the finger can seldom be felt. How- ever, in a few instances, the matter is per- ceptible at the extremity of the finger, or about the finger-joints, but, more often, in the palm of the hand, or near the wrist. In these circumstances, the tendons are in general already destroyed, and a stiffness of the finger and hand is to be apprehended When the complaint is the consequence of a puncture, the best plan, according to Richter, is at once to enlarge the wound; for, in this sort of case, all other methods are unavailing. It is not enough, however, to cut through the skin ; the tendinous theca itself must be laid. open. When a collection of matter forms to- wards the wrist, attended with violent pain in that situation, an opening must also be made there. If an opening should have been already made in the hand, a probe may be introduced into the wound, and ano- ther aperture made in an eligible situation, by cutting on the end of the instrument. In the same way, Richter advises an open- ing to be made in any part of the fore-arm, where great pain, or the symptoms of sup- puration, may indicate its propriety. In the fourth kind of whitlow, early inci- sions, made down to the bone, are the most certain means of obviating the danger. When such incisions are not made early enough, suppuration takes place, and the bone becomes carious. The cut is to be made iu the place where the pain is most severe. When the first phalanx is affected, the incision may be made in front of the finger : but when the second or third is the seat of the complaint, the opening should be made on one side. However, in order that the opening may be useful, it is absolutely necessary to make it down to the bone. When the incision is delayed too long, a small quantity of unhealthy matter is usually detected, and the bone is found in the state of necrosis. As $an exfoliation can hardly be expected in this situation, it is best to remove at once the diseased piece of bone. When the last phalanx alone is affected, the finger retains its form, with the exception of its end being a little shorter and flatter. When the disease, however, is situated in the third phalanx, Richter thinks it better to amputate the finger than remove the diseased bone, as the finger, if left, would always remain stiff and unserviceable. fSce Anfangsgr. dcr IVundarmeykunst , Pol. 7.) With regard to the treatment of the spe- cies of whitlow, named by Mr. Wardrop, onychia maligna , all local applications have, in many instances, proved quite ineffectual, and the part , been amputated. The only local treatment, which Mr. Wardrop has ever seen relieve this complaint has been the evulsion of the nail, and afterward the occasional application of escharotics to the ulcerated surface. I have myself Seen a similar plan occasionally succeed, and the applications which appeared to answer best were arsenical lotions, Plunket’s caustic, or a veiy strong solution of the nitrate of sil- ver. Nothing, however, will avail, till the nail is removed, and its total separation sometimes takes up a good deal of time, unless the patient submit to the great pain of having it cut away. Mr. Wardrop tried with success the exhi cm WOUNDS. Coition of mercury in four cases of the ony- chia maligna. The medicine was given in small doses at first, and afterward increa- sed, so as to affect the gums in about twelve or fourteen days. When the system was in this state, the sores in general soon assumed a healing appearance, and the bulbous swelling gradually disappeared. (See Med. C/nr. Trans. Vol. 5, p. 138.) WOUNDS. A great deal of the subject of wounds has been already considered in the articles, Gunshot Wounds ; Head, Inju- ries of ; Hemorrhage; Hydrophobia; Paro- tid Duct ; Sutures ; Tetanus ; Throat >' he. A wound may be defined to be a recent solution of continuity in the soft parts, sud- denly occasioned by external causes, and generally attended at first with a greater or lesser degree of hemorrhage. Wounds in general are subject to a consi- derable variety in their nature, degree of danger, facility of cure, and the consequen- ces which are to be apprehended from them. Some wounds are perfectly trivial, not extending more deeply than the skin and cellular membrane ; while others are more serious, penetrating the muscles, ten- dons, large blood-vessels, and nerves, of im- portance. There are also certain wounds which are not confined to the soft parts, but injure even the bones; such are many sabre-wounds, which frequently separate at once both a portion of the scalp and the subjacent part of the skull. Many wounds of the head, chest, and abdomen, injure the organs contained in those cavitjes. in short, the varieties, and the degree of danger, at- tending wounds in general, depend very much upon some of the following circum- stances. The extent of the injury ; the kind of instrument with which it has been inflict- ed ; the violence which the fibres of the part have suffered in addition to their divi- sion ; the size and importance of the blood- vessels and nerves which happen to be in- jured ; the nature of the wounded part in respect to its general power of healing favourably or not ; whether the operations of the system at large, “and life itself, can be well supported or not, while the func- tions of the wounded part are disturbed, interrupted, or suspended by the accident ; the youth or old age of the patient ; the goodness or badness of his constitution ; and the opportunities which there may be of administering proper surgical aid, and assist- ance of every kind. Wounds are distinguished by surgical wri- ters into several kinds ; viz. incised, punc- tured, contused, lacerated, poisoned, and gun- shot wounds. They also make another equal- ly important, division into Wounds of the Head, Thorax, Abdomen, fyc. Of gunshot wounds, and wounds of the bead, an account has already been given. (See Gunshot Wounds, and Head, Injuries of.) The other cases I shall now proceed to consider. Incised Wounds. As a general observa- tion, it may be stated, that, center is paribus, a wound, which is made with a sharp cutting instrument, which is, in short, a mere inci sion, is attended with less hazard of danger- ous consequences, than any other kind of wound whatever. The fibres have only been simply divided ; they have suffered no con- tusion nor laceration ; consequently, they are less likely to inflame severely, or to sup- purate, or slough ; and they commonly ad- mit of being united again in a very expedb tious manner. Generally simple incised wounds bleed more freely, then contused and lacerated ones, which at first sometimes scarcely pour out any blood at all, although considerable blood-vessels may be injured. But this cir- cumstance, apparently diminishing the dan- ger of contused and ' lacerated wounds, is deceitful, and serves rather to render the case in reality more perilous, by inducing the inexperienced practitioner to be off his guard against hemorrhage. Thus, in gun- shot wounds, it often happens, that on their first occurrence, the bleeding is trivial ; but the side of some large artery having suffer- ed great violence at the time of the accident, it may ulcerate or siough, a week or ten days afterward, and an alarming and even fatal effusion of blood be the result. In cases of simple incised wounds, the bleeding which at onre takes place from all the divided vessels, is a source of very use- ful information to the surgeon, inasmuch as it enables him to judge, what danger is to be apprehended from the hemorrhage, whe- ther the cut vessels are large enough to de- mand the ligature, or, on the contrary, whe- ther they are such as will cease to bleed, either by slight pressure, or of their own accord. In a recent simple incised wound, ihere are three objects which the surgeon should endeavour to accomplish, without the least delay. The first, and that which requires his immediate interference, is the bleeding, which must be checked. The sbeond is the removal of all extraneous matter from the surface of the wound. The third is the reunion of the opposite sides of the injury. When the divided vessels are not above a certain size, the bleeding soon spontaneous- ly ceases, and no surgical measures need be taken on this particular account. When the wounded vessels are even - somewhat larger, and their situation is favourable for com- pression with a bandage, it is often ndvisea- ble to close the wound and apply compresses and a roller, rather than have recourse to ligatures, which always create a certain de- gree of irritation and suppuration. However, though l have made this observation, I should be exceedingly sorry to appear at all against the general preference lo ligatures, whenever the wounded arteries are above a certain .magnitude. In this circumstance, tying the bleeding vessels is the only safe mode of proceeding. When the artery is ot considerable size, and its mouth can be readily seen, the most proper instrument for taking hold of it is a pair of forceps. In applying the ligature, the surgeon must take WOUNDS. 639 care lo puli its cuds in such a manner, that the noose will not rise above the mouth of the vessel, and for the purpose of altering the direction of the force employed in tightening the ligature, the ends of the thumbs are generally made use of. The tenaculum is commonly employed for ta- king up arteries, which are not large and distinct. Very fine ligatures, of sufficient strength, are at present often applied, as \vell to large as small vessels. One half of each ligature should always be cut off, before the wound is closed, and there are some surgeons, who prefer the method of cutting off’ all the liga- ture, except what forms the noose immedi- ately round the artery. (Delpech, M6m . sur la Pourriture d' Hdpital, p. 29; Lawrence in Med. Chir. Trans. Vol. 6, p. 156.) To the latter plan, however, a lew surgeons have addu- ced objections, particularly Mr. Guthrie, who only admits the utility of it in cases where the wound will not unite by the first intention; ( On Gunshot Wounds, 4 p. 94.) and Mr. Cross, of Norwich. (Bee the London Medical Repository , Vol. 7, p. 353.) The experiments of Mr. Cross lend to the following conclusions : First, If the wounds do not unite by the first intention, the ligatures may escape with the discharge, without any inconvenience. Secondly, If common ligatures of twine are cut short, the wound may unite over them, and they may be found in abscesses after an interval of many weeks. Thirdly, If the finest dentist’s silk be em- ployed in the same way, and the wound unite over it, the ligature may be detached from the vessel, and remain buried in an ab- scess, where it will be found at different pe- riods, from one to seven months; and this may happen, whether the vessel be firmly compressed with a single ligature, or divided between two ligatures, so as to imitate the circumstances under which vessels are tied after operations. Fourthly, If Indian silk, fine as hair, be put round a vessel so as to diminish its dia- meter, or to effect its obliteration, by just compressing its sides together, it may remain in this situation, without exciting abscess, or producing any inconvenience. The ligature may be thus applied to compress an artery for the cure of aneurism ; but not to secure vessels divided in operations. If a thin liga- ture be drawn sufficiently tight upon a ves- sel on the face of a stump to be secure, Mr. Cross is persuaded, that the extremity of the vessel which becomes insulated, as it were, must die. (See Lond. Med. Reposit. Vol. .7, pi 363.) Jt deserves attention, that the preced- ing inferences are chiefly founded on experi- ments mode upon asses and dogs. For fur- ther observations, s oo. Aneurism, Hemorrhage, Ligature, Surgery, 4"C. The bleeding having been suppressed, the next object is to remove any extraneous matter, such as dirt, bits of glass, clots of blood. &.c. from the surface of the wound. Were this circumstance neglected, the plan o f uniting the opposite sides of the cut by the adhesive inflammation, or by wbat is more frequently termed, union by the first in - tention, would in general be frustrated. As soon as attention has been paid to the foregoing indications, the surgeon must put the lips of the wound in contact, and take measures for keeping them in this state, until they have grown firmly together. The sides of incised wounds are kept in a state of apposition by means of adhesive plaster, a proper position, the pressure of a roller, and in a few particular instances, by the em- ployment cf sutures. With respect to sutures, as they create pain, irritation, and some degree of suppu- ration, they ought never to be employed when the parts can be kept in contact with- out them. However, certain cases require them, and it is admitted by many experienced surgeons, that in sabre-wounds of the ears, eyelids, nose, and lips, it is proper to use them. (See Assalini's Manuale di Chir, Parte Seconda, p. 10.) An account of the several kinds of sutures, with remarks on their employment, will be found in the arti- cle Sutures. The best and most common method of keeping the surfaces of divided parts in con- tact is by means of strips of adhesive plaster. When they are to be applied, the surgeon should pul the wounded limb or parts in the position, which is most favourable to bring- ing the lips of the wound together. With this view, a position should generally be chosen which relaxes the skin and subjacent mus- cles. An assistant should tiien place the edges of the wound as evenly together as possible, and hold them in this state, until the surgeon has secured them in this condi tion by strips of adhesive plaster, applied across the line of the wound. In general.it is deemed adviseable to leave a small inter- space of about a quarter of an inch between each two strips of plaster, by which means the matter cannot be confined in case of suppuration. Over these first strips, lint is to be applied, and kept in its place with oilier pieces of adhesive plaster. Then, if necessary, a pledget and compresses are to be put on the part, and, lastly, the bandage, or roller is to be applied. In this manner, the fresh-cut surfaces are brought into contact, and to preserve them quietly in this state, is the next great aim which the surgeon should have in view. The wounded part should be laid in the pos lure which was found the most favourable for approximating the sides of the cut at the time of applying the dressings, and the patient should be directed to keen the part in a per fectly quiet state. When attention is paid to these circuit stances, it often happens that the two oppo site surfaces of the wound grow together again in the course of forty-eight hours, without any degree of suppuration. The process by which this desirable event is ac- complished, is well known among surgeons, by the name of union by the first intention. Besides the advantage of the cure bein'-- effected in this way with the greatest exn . Paris, 1814. Larrey, M6m. de Chir. Mil- Tome 4, 8 to. 1812—17.) Sometimes the attempt to procure union by the first intention fails, even in cases of incised wounds : but, in this circumstance, no harm arises from the kind of practice which has beeirfollowed. The case, in fact, now falls into nearly the same state, as would have occurred, had no attempt at union been made at all. The patient has taken the chance of a quicker mode of cure ; but he has not been successful, and he must now be cured by a process, w hich on ac- count of its slowness he at first wished to avoid. It is to be observed also, that union by the first intention, if not spoiled by sutures, rarely fails so completely, that there is not a partial adhesion of some points of the wound. The moment when we observe pain, inflammation, and swelling of the wound, a separation or gaping of its lips, the stitches tense (when these have been used,) and the points where the stitches pass parti- cularly inflamed, Mr. John Bell advises us to undo the bandages, draw out the sutures, and take away every thing, w^hich acts like a stricture on the w'ound. These prudent measures, he observes, may abate the rising inflammation, and prevent the total separa- tion of the skin, while an endeavour may still be made to keep the edges of the wound tolerably near each other by the more gentle operation of sticking-plasters. However, when the inflammation rises still higher, and it is evident, that a total separation of the sides of the wound cannot be avoided, Mr. John Bell wisely recom- mends leaving the parts quite loose, and ap- plying a large soft poultice ; for, says he, should you in this critical juncture, persist in keeping the parts together with sutures, the inflammation, in the form oferysipelas, would extend over the whole limb, attended with a fetid and bloody suppuration the WOlviND.S. u.4-2 \vound has been brought into a favourable state, '•another attempt may be made to bring the edges near each other, not with sdfltres, but strips of adhesive plaster, or the gentle application of a bandage. Mr. John Bell concludes with remarking, that the suppuration, production of granula- tions, and all that follows, are the work of nature. The only thing that the surgeon can usefully do, is to take care of the health. When the wound does not suppurate favour- ably, the discharge generally becomes pro- fuse, thin, and gleety. This state is to be amended by bark, wine, rich diet, and good air. 1 shall conclude this subject of union by the first intention, with an extract from the writings of Mr. Hunter, who observes, that et It is with a view to this principle of union, that it has been recommended to bring the sides (or lips) of wonnds together ; but, as the natural elasticity of the parts makes them recede, it has been found ne- cessary to employ art for that purpose. This necessity first suggested the practice of sew- ing wounds, and afterward gave rise to va- rious inventions in order to answer this end, such as bandages, sticking-plasters, and liga- tures. Among these, the bandage common- ly called the uniting bandage is preferable to all the rest, where it can be employed ; but its application is very confined, from being only adapted to parts w T here a roller can be used. A piece of sticking-plaster, which has been called the dry suture, is more general in its application than the uniting bandage, and is therefore preferable to it on many oc- casions. “ I can hardly suppose (says Mr. Hunter,) a wound, in any situation, where it may not be applied, excepting penetrating wounds, where we wish the inner portion of the wound to be closed equally with the outer, as in the case of hare-lip. But even in such wounds, if the parts are thick, and the wound not large, the sides will seldom recede so far as to make any other means necessary. The dry suture has an advantage overstitches by bringing a larger surface of the wound to- gether, by not inflaming the parts to which it is applied, and by neither producing in them suppuration nor ulceration, which stitches always do. When parts, therefore, can be brought together, and especially where some force is required for that purpose, from the skin not being in large quantity, the sticking-plaster is certainly the best ap- plication. This happens frequently to be the case after the removal of tumours, in amputation, or where the sides of the wound are only to be brought together at one end, as in the hare-lip ; and I think the difference between Mr. Sharp’s cross-stitch, after ampu- lion, as recommended in his Critical Inquiry, and Mr. Allanson’s practice, shows strongly he superiority of the sticking-plaster (or dry suture,) In those parts of the body where t.ue skin recedes more than in others, this ''routine nt becomes most necessary ; and as !*><• y-*vlp probably recedes as little a-s rtu.y, *t is therefore seldom iieceasary to app^y any thing in wounds of that part ; the practice will certainly answer best in superficial wounds, because the bottom is in these more within its influence. “ The sticking-plasters should be laid on in strips, and these should be at small dis- tances from each other, viz. about a quarter of an inch at most, if the part requires close confinement ; but when it does not, they may be at greater distances. This precaution becomes more necessary if the bleeding is not quite stopped ; there should be passages left for the exit of blood, as its accumula- tion might prevent the union, although this does not always happen. If any extraneous body, such as a ligature, should have been left in the wound, suppuration will take place, and the matter should be allowed to vent at some of these openings, or spaces, between the slips of plaster. 1 have known a very considerable abscess formed in con - sequence of this precaution being neglected, by which the whole of the recently united parts has been separated. “ The interrupted suture, which has gene- rally been recommended in large wounds, is still in use, but seldom proves equal to the intention. This we may reckon to be the only one that deserves the name of su- ture ; it was formerly used, but is now in a great measure laid aside in practice, not from (he impropriety of uniting parts by this process, but from the ineffectual mode of attempting it. In what manner better methods could be contrived^ 1 have not been able to suggest. It is to be understood, that the above methods ofsbringing wounded parts together, in order to unite them, are only to be put in practice in such cases as will admit of it} for if there was a method known, which in all cases would bring the wounded surfaces into contact, it would, in many instances, be improper, as some wounds are attended with contusion, by which the parts have been more or less deadened ; in such cases, as was formerly observed, union ^cannot take place accord- ing to our first principle, and therefore it is improper to attempt it. “In many wounds, which are not attend- ed willi contusion, when we either know, or suspect, that extraneous bodies have been introduced into the wound, union by the first intention should not be attempted, but they should be allowed to suppurate, in or- der that the extraneous matter may be ex- pelled. Wounds which are attended with laceration, although free from contusiou, cannot always be united by the first inten- tion, because it must frequently be impossi- ble to bring the external parts, or skin, so much in contact, as to prevent that inflam- mation which is naturally produced by ex- posure. But even in cases of simple lacera tion, where the external influence is but slight, or can be prevented (as we observed in treating of the compound fracture,) we find that union by the first intention often takes place ; the blood, which fills up the hiterstvw of the lacerated parts, having prf • WOfcJNliS ■'vented the siiuiuius ot imperfection in them, and prevented suppuration, muy afterward be absorbed. te Many operations may be so performed as to admit of parts uniting by the first in* tention ; but the practice should be adopted with great circumspection : the mode of operating with that view, should in all cases be a secondary, and not a first considera- tion, which it has unluckily been too often among surgeons. In cases of cancer, it is a most dangerous attempt at refinement in surgery. “ In the union of wounded parts by the first intention, it is hardly or never possible to bring them so close together at the expo- sed edges, as to unite them perfectly by these means; such edges are therefore obliged to take another method of heuiing. If kept moist, they will inflame as deep be- tween the cut surfaces as the blood fails in the union, and there suppurate and granu- late ; but if the blood be allowed to dry and form a scab between, and along the cut edges, then inflammation and suppuration of those edges will be prevented, and (his \vill complete the union, as will be descri- bed by and by. “ As those effects of accidental injury, which can be cured by the first inteution, call up none of the powers of the constitu- tion to assist in the reparation, it is not the least affected or disturbed by them ; the parts are united by the extravasated blood alone, which was thrown out by the injury, either from the divided vessels, or in conse- quence of inflammation, without a single action taking place, even in the part itself, except the closing or inosculation of the vessels : for the flowing of the blood is to be considered as entirely mechanical. Even in cases where a small degree of inflamma- tion comes on, it is merely a local action, and so inconsiderable, that the constitution is not affected by it ; because it is an opera- tion, to which the powers belonging to the parts themselves are fully equal. The in- flammation may produce a small degree of pain, but the operation of union gives no sensation of any kind whatever.’ 1 ( Hunter on the Blood , Inflammation, and Gunshot Wounds .) Contused and Lacerated Wounds. — Lace- rated wounds are those, in which the fibres, instead of being divided by a cutting instru- ment, have been torn asunder by some vio- lence, capable of overcoming their force of adhesion. The edges of such wounds, in- stead of being straight and regular, are jag- ged and unequal. The term contused is applied to those wounds which are occasioned by some blunt instrument, or surface, which has violently struck a part of the body. These two species of wounds greatly re- semble each other, and astheyrequire nearly the same kind of treatment, writers usually treat of them together. Lacerated and contused wounds differ from simple incised ones, in appearing, at first view, much less alarming than the tat- bd3 ter, while, in reality, they are infinitely more dangerous. In simple cut wounds, the retraction of the parts, and the hemorrhage, are generally much more considerable than in a lacerated wound of the same size. However, notwithstanding these circum stances, they commonly admit of being healed with far greater ease. It is worthy of particular notice, that lacerated and con- tused wounds are not in general attended with any serious effusion of blood, even though large blood-vessels may be injured. I say in general, because in the year 1813, I saw a soldier, whose death was occasioned by a sudden effusion of a very large quan- tity of blood from the internal jugular vein, which vessel had been injured by a muskel- ba.Il, that first entered the integuments be- hind the mastoid process, and passed ob- liquely downwards and forwards towards the sternum. The blood did not issue ex- ternally; but formed betwixt the integu- ments and the trachea, a large dark-coloured swelling, which produced almost immediate suffocation. At the memorable siege of Saragossa, Professor Assalini saw a surgeon whose left carotid artery had been injured by a musket-bail, perish of hemorrhage in a few seconds. (See Assalini’s Manuale di Chirurgia, p. 32, Milano, 1812.) In most cases, however, there is little or no hemorrhage from lacerated and contused wounds, and it is a circumstance, which often leads inexperienced practitioners to commit great mistakes, by inducing them to promise too much in the prognosis which they make. Surgeons versed in practice, however, do not allow themselves to be de- ceived by the absence of hemorrhage, and, in proportion as there is little bleeding, they apprehend that the violence done to the fibres and vessels has been considerable. What is it, but the contused and lacerated nature of the wound, that prevents hemor rhage from the umbilical arteries, u'hen ani mals divide the navel-string with their teeth ? Whole limbs have frequently been torn from the body, without any hemorrhage of con- sequence taking place. In the Phil. Trans. Cheselden has recorded a very remarkable case, in which a man’s arm was suddenly torn from his body. Samuel Wood, a miller, had round his arm a rope, which got entangled with the wheel of the mill. He was lifted off the ground, and then stopped by a beam, which pre vented his trunk from passing further ; at this instant, the wheel, which was moving with immense force, completely tore, and carried away, his arm and scapula from his body. The appearance of a wound, occa- sioned in this manner, must of course be horrible, and the first idea, thence arising, must naturally be that the patient cannot possibly survive. Samuel Wood, however, escaped with his life. The limb had been torn off with such velocity, that he was un- aware of the accident, till he saw his arm moving round on the wheel. He immedi- ately descended by a narrow ladder from the mill, and even walked some pacers, with WOUNDS. I >tt d a view of seeking assistance. He now fell ^lowii from weakness. The persons who first came to his assistance, covered the wound with powdered sugar. A surgeon, \vno afterward arrived, observing that there was no hemorrhage, was content with bringing down the skin, which was very loose, so as to make it cover the surface of the wound. For this purpose he used two cross stitches. The patient was conveyed the next day to St. Thomas’s Hospital, and put under the care of Mr. Fern. This prac- titioner employed the usual means for pre- venting the bad symptoms most to be ex- pected in this sort of case. The first dress- ings came away without any bleeding; no alarming consequences ensued ; and the patient, in two months, completely reco- vered. When the arm was examined, it was found, that the muscles, inserted into the scapula, were torn through near their inser- tions ; while other muscles, arising from this bone, were carried away w ith it. The skin, covering the scapula, had remained in its natural situation, and seemed as if it had been divided precisely at the insertion of the deltoid muscle. In La Motte’s Trait6 des Accouchemtns, may be found an account of a little boy, who, while playing near the wheel of a mill, got his hand, fore-arm, and arm, suc- cessively entangled in the machinery, and the limb was violently torn away at the shoulder joint, in consequence of the lad’s body not being able to pass in the direction Id which the arm w as drawn. The bleed- ing was so trivial, that it was stopped with a Tittle lint, and tiie boy very soon reco- vered. In the fifth vol. of the Edinb. Med. Com- mentaries, may also be perused the history of a child, three years and a half old, whose arm was torn off by the wheel of a mill. Mr. Carmichael, who saw the child about an hour after the accident, found it almost in a dying state, with cold extremities, small faltering pulse, and all the right side of the body convulsed. However, there was hardly any bleeding. The arm was broken about an inch and a half above the elbow ; the stump had a dreadful appearance ; all the soft parts were in a contused and lace- rated stale, and the humerus was laid bare as high as the articulation, which was itself exposed. The skin and muscles were lace- rated to a much greater extent, and in dif- ferent directions. The remainder of the humerus was removed from the shoulder- joint by amputation, only as much skin and tnuscle being left as was sufficient to cover the wound. In two months the child was well. In the M6m. de VAtad. de Chir. T. 2, is an account of a leg being torn away at the knee-joint by a cart wheel. The pa- tient was a boy, about nine or ten years of age. This accident, like the foregoing ones, was accompanied with no hemorrhage. The lower portion of the os femoris, whieh was exposed, was amputated, together with such portion ot the soil parts, as was in a contused and lacerated state. The patien; experienced a perfect recovery. The preceding cases strikingly confirm the observation, which I have already made, in regard to the little bleeding, which usu- ally arises from contused and lacerated wounds. In these instances, the pain is also in an inverse ratio to the cause of the accident; it is generally very severe, when the wound is only moderately contused : and, on the other hand, the patient scarcely suffers any pain at all, where there has been so violent a degree of contusion, as at once to destroy the organization of the part. When the bruised fibres have not been injured above a certain degree, the part suppurates ; but such portions of the wound as have suffered greater violence, inevitably die, and are cast off in the form of sloughs. Granulations are afterward formed, arid the breach of continuity is repaired by the process of cicatrization. (See this word.) When a still greater degree of violence has been done, and, especially, when arte- ries of a certain magnitude have been in jured, a mortification is too frequently the consequence. However, if the constitution be good, and the mischief not too extensive, the case may still end well. But, in other instances, the event is alarmingly dubious ; for the mischief is then not limited to the wounded parts, which have suffered the greatest degree of contusion ; but, too fre- quently, extends over such parts as were not at all interested by the wound itself. The mortification arising directly from the impaired organization of parts, is not what is the most alarming circumstance. A still more dangerous kind of mortification, is that which is apt to originate from the violent in- flammation occasioned by the accident. This consequence demands the utmost attention on the part of the surgeon, who must let no u«eful means be neglected, with a view of diminishing the inflammation before it has attained too high a degree, and very danger- ous symptoms have commenced. In the first instance, he should not be afraid of let- ting the wound bleed a little, if it should be disposed t:* do so. The ediies of the wound should then be gently drawn towards each other with a few strips of sticking-plaster, so as to lessen the extent of the exposed sur- face . hut no sutures are proper. Indeed, the plan of diminishing the exposed surface of a contused wound with strips of adhe- sive plaster, is not invariably right ; because their application creates a hurtiul degree ot irritation. The method is chiefly advisenble when there is a large loose flap of skin, which can be conveniently brought over the wound. In other cases, it is best to leave the parts free, uncompressed, and unconfined With any adhesive plaster, because if it were applied its irritation would do barm, and could not possibly procure any union of The parts. Under the most favourable circum- stances, hardly any part of the wound can be expected to unite by the first intention WOUNDS. Ine whole or the greater part of it will neces- sarily suppurate, after the detachment of the sloughs. The surface will then granulate, new skin will be formed, and the part heal just like a common wound. Perhaps, until the sloughs separate, the best application is a soft poultice, which should be put on cold, lest it bring on too great an oozing of blood. Nothing, indeed, is so proper for checking any tendency to hemorrhage as cold applica- tions, which are also the most effectual in preventing and diminishing the great degree of inflammation, which is one of the most dangerous consequences of this description of wounds. No surgical writer, I think, has given more rational advice, respecting contused wounds, than that published by Professor Assalini. In general, says he, the treatment of contused wounds, whether they be simple and slight, or complicated and severe, re- quires the active employment of debilitating means in order to prevent inflammation. Cold water, and ice ; and general and topi- cal bleeding, are the things usually resorted to with success. Vulnerary lotions, campho- rated spirit, and other spirituous applications, are improper, and if their pernicious effects are not always very evident, it is only be- cause the contused injuries have been trifling, and in their nature perfectly easy of cure. In these cases, as well as in those of extravasa- tions and glandular swellings, Assalini gives a preference to cold applications. The in- ternal remedies and regimen, (says he) should also be adapted to the condition of the patient. A cannon-ball, at the end of its course, may come into contact with a limb, and fracture the bones, while the inte- guments have the appearance of being unin- jured. Such cases are often attended with dreadful mischief in the soft parts around the bone, which generally sphacelate. This is an accident for which immediate amputa- tion is mostly indispensable (see Gunshot Wounds;) but if any thing be capable of pre- venting inflammation and gangrene, it is an active debilitating plan of treatment, assisted with cold applications to the injured part. In such cases, the internal and external use of stimulants is approved of by many sur- geons. But, Assalini prefers considering the state of the injured limb, just like what it is when affected with frost ; and he thinks that the employment of stimulants will neces- sarily produce the same effect as caloric prematurely applied to parts deadened with cold. On the contrary, from the outward employment of ice and cold lotions in tb.ese cases, and in contused injuries in general, he has seen the greatest benefit derived. Assalini conceives, that reason will be found to support this practice. The opera- tion of cold, he says, retards the course of the blood, which meeting with only dama- ged vessels, augments the extravasation as it continues to flow. By lessening the tem- perature of the part, cold applications like- wise diminish the danger of inflammation and sphacelus, at the same time that they o4o have the good effect Of rendering the suppu ration, which must qnsue, less profuse, than it would be, were not extravasation of blood, and violence of the inflammation, lessened by such applications, and a lowering plan of treatment. Why, says Assalini, should not this me- thod, which is generally adopted to prevent the effects of concussion of the brain after blows on the head, be, for analogous reasons, employed in examples of extravasation and commotion in other parts of the body ? ( Manuale de Chirurgia, Parte Prima t p 17.) Cold applications, however, in cases of con- tused wounds, are chiefly to be preferred, for the first day or two, in order to check the increase of extravasation and inflammation. After this period, l give a decided preference to an emollient linseed poultice, which will be found the most easy dressing during those processes, by which the slougii3 are detached, the surface of the wound cleansed, and the origin of granulations established. When these changes have happened, the remaining sore is to be treated on the same principles as ulcers in general. See Ulcers. Punctured Wounds. — A punctured wound signifies one, made with a narrow-pointed instrument, the external orifice of the injury being small and contracted, instead of being ofasize proportionate to its depth. A wound, produced by a thrust of a sword, or bayonet, affords us an example of a punctured wound. Wounds of this description are in general infinitely more dangerous than cuts, notwith- standing the latter have the appearance of being by far the most extensive. In cases of stabs, the greatest degree of danger al- ways depends on the injury, and rough vio- lence which the fibres have suffered, in ad- dition to their mere division. Many of the disagreeable consequences are also to be imputed to the considerable depth, to which these wounds extend, whereby important parts and organs are frequently injured. Sometimes the 'treatment is rendered per- plexing, by the difficulty of removing ex- traneous substances, as forinstancea piece of the weapon, which has been left in the wound. Lastly, experience proves, that punctured wounds and stabs are particularly liable to be followed by a great deal of in- flammation, fever, deep seated abscesses, si- nuses, fee. A strange notion seems to pervade the writings of many systematic authors, that all the danger and disagreeable consequences of punctured wounds are entirely owing to the narrowness of their orifices, which pre- vents suitable applications from being made to their bottom. Hence, it is absurdly re- commended to dilate th* opening of every slab, with the view, as is generally added, of converting the accident into a simple inci- sed wound. Some of these writers are advo- cates for making the dilatation with a cutting instrument, while others, with equal absurdi- ty, propose to enlarge the opening with tents. Certain authors regard a punctured 'wound, as a recent sinus, and in order to make the inner surfaces unite, they recommend ex- IYOUjSUs. <>4i> citing a degree of inflammation in them, either l>y means of setons, or injections. In the earliest edition of The First Lines of the Practice of Surgery, I have taken parti- cular pains to expose the folly and errors, which prevail in most writings on this part of practice. In the above work, I have re- marked, that if the notion were true, that an important punctured wound, such as the stab of a bayonet, could be actually chan- ged into a wound, partaking of the mild nature of an incision, by the mere enlarge- ment of its orifice, the corresponding prac- tice would certainly be highly commenda- ble, however painful. But the fact is other- wise : the rough violence, done to the fibres of the body by the generality of stabs, is little likely to be suddenly removed by an enlargement of the wound. Nor can the distance, to which a punctured wound fre- quently' penetrates, and the number and na- ture of the parts injured by it, be at all altered by such a proceeding. These, which are the grand causes of the collections of matter, that often take place in the cases under consideration, must exist, whether the mouth and canal of the wound be enlarged or not. The time when incisions are pro- per, is w’hen there are foreign bodies to be removed, abscesses to be opened, or sinuses to be divided. To make painful incisions sooner than they can answer any end, is both injudicious and hurtful. They are sometimes rendered quite unnecessary, by the union of the wound throughout its whole extent, without any suppuration at all. Making a free ineision in the early stage of these cases, undoubtedly seems a reasona- ble method of preventing the formation of sinuses, by preventing the confinement of matter, and were sinuses an inevitable con- sequence of all punctured wounds, for which no incisions had been practised at the moment of their occurrence, it would un- doubtedly be unpardonable to omit them. Fair, however, as this reason may appear, it is only superficially plausible, and a small degree of reflection soon discovers its want of real solidity. Under what circumstances do sinuses form ? Do they not form only where there is some cause existing to pre- vent the healing of an abscess ? This cause may either be the indirect way, in which the abscess communicates externally, so that the pus does not readily escape ; or it maybe the presence of some foreign body, or carious bone ; or lastly, it may he an in- disposition of the inner surface of the ab- scess to form granulations, arising from its long duration, but removable by laying the cyst completely open to the influence of the air. Thus it becomes manifest, that the occurrence of suppuration in punctured wounds is followed by sinuses only when the surgeon neglects to procure a free issue for the matter, after its accumulation ; or when he neglects to remove any extraneous bodies. But as dilating the wound at first can only tend to augment the inflammation, nnd render the suppuration more extensive. it ought never to be practised in tnese casev. except for the direct objects of giving free exit to matter already collected, and of being able to remove extraneous bodies palpably lodged. I shall once more repeat, that it is an erroneous idea to suppose the narrowness of punctured wounds so princi- pal a cause of the bad symptoms, with which they are often attended, that the treatment ought invariably to aim at its, re- moval. Recent punctured wounds have absurdly had the same plan of treatment applied to them as old and callous fistuhe. Setons and stimulating injections, which in the latter cases, sometimes act beneficially, by exci- ting such inflammation as is productive of the effusion of coagulating lymph, and of the granulating process, never prove ser- viceable when the indication is to moderate an inflammation, which is too apt to rise to an improper height. The counter-opening, that must be formed in adopting the use oi a seton, is also an objection. However, what good can possibly arise from a setou in these cases? Will it promote the dis- charge of foreign bodies, if any are present : By occupying the external openings of the wound, will it not be more likely to prevent it ? In fact, will it not itself act with all the inconveniences and irritation of an extra- neous substance in the wound ? Is it a likely means of diminishing the immoderate pain, swelling, and extensive suppuration, so often attending punctured wounds ? It will un- doubtedly prevent the external openings from healing too soon ; but cannot this ob- ject be effected in a better way? If the sur- geon observes to insinuate a piece of lint into the sinus, and pass a probe through its track once a day, the danger of its closing too soon will be removed. The practice of enlarging punctured wounds by incisions, and of introducing se- tons, is often forbidden by the particular situation of these injuries. In the first stage of a punctured wound, the indication is to guard against the attack of violent inflammation. When no con- siderable quantity of blood has been lost, general and topical bleeding should be prac tised. In short, the antiphlogistic plan is tu be followed. As no man can pronounce, whether such wounds will unite or not, and as no harm can result from the attempt, the orifice ought to be closed, and covered with simple dressings. In such cases, cold appli- cations are also highly commendable. Whe- ther gentle compression might be made to promote the adhesive inflammation or not, may be doubtful : l confess, that I should not haVe any reliance upon its usefulness. Perfect quietude is to be observed. When the pain is severe, opium is to be adminis- tered. Sometimes under this treatment, the sur geon is agreeably surprised to find the con- sequent inflammation mild, and the wound speedily united by the first intention. u Nu- merous are the examples ol wounds, which penetrate the lapge ravifies. being healed by wu the iVrkt intention, tiial is, ui-tiiout any sup- puration. Even wounds of the chest itself, with injury of the lungs (continues an ex- perienced military surgeon and professor,) ought to be united by the first intention. (Jlssalini, in Mnnuale di Chirurgia, parte Scconda , p. 13.) More frequently, however, in cases of deep stabs, the pain is intolera- ble; and the inflammatory symptoms run so high as to leave no hope of avoiding sup- puration. In this condition, an emollient poultice is the best local application ; and when the matter is formed, the treatment is like that of abscesses in general. See Sup- puration. Poisoned IVounds: Bite of ike Viper . — If we exclude from present consideration the bites of mad dogs, and other rabid animals, which subject is fully treated ot in the ar- ticle Hydrophobia, wounds of this descrip- tion are not very eommon in these islands. In dissections, pricks of the hand sometimes occur, and they are in reality a species of poisoned wound, frequently causing consi- derable pain and irritation in the course of the absorbents ; swelling and suppuration of the lymphatic glands of the arm or axilla; and severe fever and constitutional irrita- tion. An instance of the fatal consequences of such an injury must still be fresh in the recollection of the profession ; and some others of yet more reoent date have taken place in this metropolis. (See London Me- dical Repository, Vol. 7, p ■ 288.) In many instances, however, surgeons wound their fingers in dissecting bodies, and no particular ill consequences ensue. The healthy and robust are said to suffer less frequently after such accidents, than persons, whose constitutions have been weakened by hard study, excesses, pleasure, or previous disease. It is remarked, also, that pricks of the lingers, met with in open- ing the bodies of persons who have died of contagious diseases, and where a virus or infectious matter might be expected to exist in such bodies, do not communicate the in- fection. Doubtless (observes Richerand) the activity of certain animal poisons, from which the venereal and several other dis- eases arise, is extinguished with life. (JVb- sographie Chir. T. 1 ,p. 102, 103. Edit. 4.) With regard to the treatment of the pricks of dissecting scalpels, the surgeons of the continent recommend the immediate cauterization of the little wounds with a grain of caust ic potassa, or the liquid muri- ate of ammonia. Tonic remedies, particu- larly wine, is prescribed, and great atten- tion paid to emptying the bowels. The stings of bees, wasps, and hornets, are also poisoned wounds, though ^ftey are .seldom important enough to require the assistance of a surgeon. The hornet is not found in Scotland; but it is an inhabitant of several of the woods in England. Its sting, which is more painful than that of a bee, or wasp, is not, however, often the occa- sion of any serious consequences. 1'he stings of all these insects are attended with a vhn-ro pain in the part, very muckly suc- ceeded by an inflammatory swelling, which, after a short time, generally subsides of it- self. When the eye is stung, as sometimes has happened, the e fleets may be very se- vere, as is elsewhere noticed. (See Ophthal’ my.) It has been lately observed, that the pain of the stings of venomous insects, like the bee, depends less upon the introduction of the sting into the part, than upon that of the venomous fluid. The experiments of Professor Dumeril tend to prove, that when the little poison bladder, situated at the base of the sting, has been cut off, a wound with the sting then produces no pain. The poison flows from the vesicle through the sting at the instant when this passes into the flesh. The exact nature of this venomous fluid is not known. When applied to mu- cous surfaces, or even to the surface of the conjunctiva of the eye, it causes no dis- agreeable sensation ; but when it is intro- duced into the skin, by means of a needle, it immediately excites very acute pain. Oil, honey, spirits of wine, the juice of the plantain, and a variety of other local applications, have been extolled as specifics lor the relief of the stings of insects. Mo- dern experience, however, does not sanc- tion their claim to this character. In fact, none of these applications either neutralize the poison, or appease with superior efficacy the pain of the sting These cases should all be treated on com- mon antiphlogistic principles, and the most rational plan is to extract the sting, taking care, in the first instance, to cut oft* the little poison vesicle with scissors, lest in the at- tempts to withdraw the sting more of the virus be compressed into the part. The stung part should then be immersed for a time in ice-cold water, anc! afterward co- vered with linen, wet with the liquor plumbi acetatis dilutus. Were the inflammation to exceed the usual degree, leeches and aperi- ent medicines would be proper. In short, as there is no specific for the cure of these cases, they are to be treated with common antiphlogistic means. With regard to the bites of serpents, those inflicted by the rattle-snake of Ame- rica, and the cobra di capello of the East Indies, are the most speedily mortal. In- deed, this is so much the case, that some- times there is scarcely an opportunity of trying any remedies ; and even when the patient is not destroyed thus rapidly, there is such general disorder of the nervous sys- tem, with repeated faintings arid sickness, that medicines cannot well be retained in the stomach, at least for some time. Mr. Catesby, in the Preface to his Natural History of Carolina, informs us, that the Indians, who, by their constant wanderings hi the woods, are liable to be bit by snakes, know, as soon as they receive the injury, whether it will prove mortal or not. If it be on any part at a dislance from largo blood-vessels, or where the circulation is not vigorous, they apply their remedies ; but if any vein of considerable magnitude be hurt, they qnietlv resign themselves to WB WOUNDS. their fate, knowing that nothing can then be of service. Among the remedies on which they chiefly depend are seneka root, volatile alkali, and particularly strong doses of arsenic, as will be presently noticed again. If we put out of consideration animals affected with rabies, the viper inflicts the 'worst poisoned wound ever met with in these islands. In fact it is an animal which inserts into the part w hich it bites a poison capable of exciting very serious conse- quences. The jaws of the viper are fur- nished with teeth, two of which in the upper jaw are very different from the rest. These, w hich are about three lines long, are covered for about two-thirds of their length, with a membranous coat or sheath, are of a curved shape, and articulated with the jaw- bone. When the animal is tranquil, and his mouth shut, they lie dowm with their points turned backwards 3 but they instantly project forwards when it is irritated, and about to bite. In them are canals, which terminate by a very narrow fissure on their convex sides, a little way from their points. The rest of these fangs is very hard and solid ; and the canal is usually filled with a transparent, yellowish fluid, the poison of the viper. This venomous fluid is secreted by two glands, or rather by two clusters of glands, one on each side of the head, placed on the front of the forehead, directly behind the eye-ball, under the muscle, which serves to depress the upper jaw. Thus the muscle cannot act without pressing upon them, and promoting the secretion of the fluid, which they are destined to prepare. A little bag, or vesicle, connected to the base of the first bone of the upper jaw, as well as to the end of the second, covers also the roots of the curved fangs, and forms a receptacle for the venom. The viper is chiefly found in hilly, stony, and w r oody districts, and seldom in flat or marshy places. It is not its nature to at- tack man, or large animals, except when provoked. Its venom is only employed for the destruction of smaller animals, such as mice, frogs, k.c. which are usually swallow- ed w hole, and to the digestion of which the venomous secretion is by some writers sup- posed to contribute. When, however, a viper is pursued, trod upon, taken hold of, or hurt, it immediately bites, and were it only on account of the shape of the fangs, the wound might be attended w ith very un- pleasant effects; but it is certain of being so, by reason of the species of inoculation which complicates it, and of which the mechanism is as follows : When a viper is about to bite, it opens its mouth very wide. The two curved fangs, which had previously lain flat down in the cavity of the membrane attached to their base, now project, and become perpendicu- lar to the low er jaw. When the bite takes place, the poison is propelled through the fangs, by t lie contraction of the muscles, and the closure of the mouth, and is in- jected into the wound with a force propor- tioned to its accidental quantity at the time, and the vigour of the animal. The bite of a viper is quickly followed by severe effects, some of w'hich are local, and the others general ; but it is with the former that the disorder invariably commences. At the instant of the bite, the bitten part is seized with an acute pain, which rapidly shoots over the whole limb, and even affects the viscera and internal organs. Soon after- ward the w’ounded part swells and reddens. Sometimes the tumefaction is confined to the circumference of the injury ; but most frequently it spreads extensively, quickly affecting every part of the limb, and even the trunk itself. A sanious fluid is often discharged from the wound, around which phlyctenas arise, similar to those of a burn. After a short time, however, the pain abates considerably ; the inflammatory tension changes into a doughy, or oedematous soft- ness ; the part grow's cold; and the skin exhibits large livid spots, like those of gan- grene. The general symptoms also come on with celerity ; the patient is troubled with anxiety, prostration of strength, diffi- culty of breathing, and cold profuse sweats Vomiting frequently occurs, and sometimes copious bilious evacuations from the bowels These symptoms are almost constantly at- tended with an universal yellowness, and excruciating pain about the navel. The effects occur in the same way in nearly all subjects, with some differences depending upon the particular irritability and constitution of the patient ; the high or low temperature of the atmosphere ; the greater or lesser anger of the viper ; the number of its bites; the size of the reptile itself ; the depth to which the fangs have penetrated ; and whether the bitten part happens to be one of great sensibility, or w as naked or not at the time of the acci- dent. In general, weak, pusillanimous persons, of bad constitutions, and loaded stomachs, suffer more sudden and alarming ill consequences, than strong, healthy sub jects, wdio view 7 the danger without fear Several bites are, of course, more danger- ous than a single one ; and, lastly, it has been remarked, that the venom of the viper is more active in summer than the spring. A year or two ago, however, the news papers recorded the death of a servant, from the inadvertent application of the poi- son to a scratch on his hand, as he was exa- mining the fangs and venomous organs of a viper perfectly torpid in the winter season. Severe, however, as the effects of the bite of a viper may be, they are far from being so perilous as they are commonly supposed to be. Indeed, the injury rarely proves fatal to an adult, even when inflicted by a viper in the middle of summer, the period when the animal is mo3t active and vigorous. Exceptions to this common be- lief, however are upon record. Thus in the year 1816, a vvomaD, in France, aged sixty-four, was bit ou the thigh by a viper, and. died in thirty-seven hours, notwith- WOUNDS. standing the internal use of the liquor am- monite, and the enlargement of the wound, and cauterization of it with this fluid. In this case, it is to be observed, that an hour elapsed before any thing was done. (See Annalts du Cercle Medicate , T. 1, P- 43, S vo. Paris, 1820.) Fontana, therefore, was not exactly cor- rect in concluding, that the bite of an ordi- nary viper will not prove fatal to a full- grown person, nor even to a large dog, though it does so to smaller animals. Five bites from three strong and healthy vipers were not able to kill a dog weighing sixty pounds; and as this dog was little more than a third part of the weight of an ordi- nary man, Fontana supposed that a single bite could never be fatal to an adult. He says, that he had seen a dozen cases himself, and had heard of fifty more, only two of which ended fatally. Concerning one of these cases, he could get no information ; the other patient perished of gangrene, twenty days after the bite. The mortifica- tion began three days after the accident, the bitten place having been deeply scarified almost as soon as the injury was received. Fontana believes, that much of the faint- ness, &.c. which ensues upon the bite of a viper, are the mere effects of terror. “ Upon a person’s being bit (says he; the fear of its proving fatal terrifies himself and the whole family. From the persuasion of the disease being mortal, and that not a mo- ment is to be lost, they apply violent or hurtful remedies. The fear increases the complaint. I have known a person that was imperceptibly bit in the hands or feet, and who, after seeing the blood, and ob- serving a viper near him, suddenly fainted away ; one, in particular, continued in a swoon for upwards of an hour, until he was accidentally observed, and recovered out of it by being suddenly drenched in cold water. We know that death itself may be brought on by very violent affections of the mind, without any internal disease. Why may not people, that are bit, die from a dis- ease, produced entirely from fear, and who would not otherwise have died from any complaint produced by the venom ?” Al- though it must be owned, that Fontana be- stowed a great deal of attention upon this subject, the above reasoning is hypothetical and inconclusive. If it were to be granted, that some very timid, delicate, or nervous people, die from fear alone, it could not be admitted, that the generality of people, bit by snakes, perish also from the violent effect of mental alarm. Whenever the patient dies, the catastro- phe is always ascribable to the quantity of venom inserted in the wound ; the number of bites ; their situation near important or- gans ; and the neglect of proper means of relief. In ordinary cases of a single bite upon the extremities, the patients would get well even without any assistance ; but the symptoms would probably be more severe, and the cure slower. Vox.. IF 649 From some facts, recorded by Sir Everard Home, and observations made on the opera tiou of the poisons of the black spotted snake of St. Lucia, the cobra di Capello, and the rattlesnake, it appears, that u the effects of the bite of a snake, vary according to the intensity of the poison. When the poison is very active, the local irritation is so sud- den, and so violent, and its effects on the genera! system are so great, that death soon takes place. When the body is afterward inspected, the only alteration of structure met with, is in the parts close to the bite, where the cellular membrane is completely destroyed, and the neighbouring muscles very considerably inflamed. • When the poi- son is less intense, the shock to the general system does not prove fatal. It brings on a slight degree of' delirium, and the pain in the part bitten is very severe : in about half an hour, swelling takes place from an effusion of serum in the cellular membrane, which con- tinues to increase, with greater or less ra- pidity, for about twelve hours, extending, during that period, into the neighbourhood of the bite. The blood ceases to flow in the small vessels of the swollen parts ; the skin over them becomes quite cold ; the action of the heart is so weak, that the pulse is scarcely per- ceptible, and the stomach is so irritable that nothing is retained by it. In about sixty hours , these symptoms go off ; inflammation and sup- puration take place in the injured parts; and when the abscess formed is very great, it proves fatal. When the bite has been in the finger, that part has immediately mortified. When deaih has taken place, under such cir- cumstances, the absorbent vessels, and their glands have undergone no change, similar to the effects of morbid poisons, nor has any part lost its natural appearance, except those im- mediately connected with the abscess. In those patients, who recover with difficulty from the bite, the symptoms, produced by it, go off more readily, and more complete- ly, than those produced by a morbid poi son, which has been received into the sys- tem.'’ ( Sir E. Home, Case of a Man who died in Consequence of the Bite of a Rattle Snake, in Phil. Trans. 1810.) Numerous remedies for the bites of com mon vipers have obtained celebrity. Ac cording to certain writers, each of these re medies has effected wonderful cures ; and yet, as Boyer well remarks, every one of them has been in its turn relinquished for another, the sole recommendation of which has frequently consisted in its novelty. Any of these boasted medicines, though of oppo site qualities, cured, or at least seemed to cure, the patients, and the partisans of each considered, that he had a right to extol his own remedy as a specific, when the patient, to whom he administered it, was seen to re- cover perfectly, after suffering a train of se- vere symptoms. But the reason of this pre- tended efficacy becomes obvious, when one knows that the bite of a viper is of itself rarely mortal to the human subject, and that the severity of the symptoms materially de- pends upon the quantity of the venom in the 82 WOUNDS wound. {Boyer, TraiU des .Maladies Chir. T. 1 ,p. 428.) The treatment of the bite of a viper is di- vided into local and general means. . The local treatment has for its principal object the destruction of the venom ; the prevention of its entrance into the vessels, or the removal of it from the wound. Ot scarifying the wound, I shall only say, that it promises no utility, if it be practised with a view of letting such dressings be ap- plied, as are extolled as specifics ; for we know, that there is no local application, which is entitled to this character. Fontana was an advocate for applying a ligature round the lirnb,*in order to check the ingress of the venom into the circulation ; and he thought, that he had seen much good result from this practice. Sir Everard Home is also of opinion, that “ the only rational lo- cal treatment,to prevent the secondary mis- chief, is making ligatures above the tumefied part, to compress the cellular membrane, and set bounds to the swelling, which only spreads in the loose parts under the skin ; and scarifying freely the parts already swoln, that the effused serum may escape, and the matter be discharged as soon as it is formed. Ligatures (he says) are employed in Ameri- ca, but with a different view, viz. to prevent the poison being absorbed into the system.” (Phil. Trans, for 1810, p. 87.) At all events, if compression be employed, it should be so regulated as not to create any risk of gangrenous mischief, by its interruption of the circulation. Suction of the wound has been proposed, and seems founded on reason ; but experi- ence, I believe, has determined little in its favour. A cupping-^lass might be employed, but, probably, no mode of suction would succeed in extracting the whole of the poi- son. The most certain method of removing the virus consists in the excision of the bitten part. This operation, however, would hardly be proper, unless done immediately after the injury, before much inflammation had come on. It is likewise a practice to which many patients would not assent, and even some surgeons may deem the proceeding too se- vere, in relation to the bite of the viper of this country. The bite might also be incon- veniently situated for the excision of the parts. Another plan, more commonly preferred is, that of destroying the envenomed part with caustic, or the actual cautery. When this is done in time, the poison is prevented from extending its irritation over the ner- vous system, through the medium of which all the worst symptoms are usually excited. The caustic and cautery may also have the effect of chymically destroying the venom itself, while they must tend to hinder its passage into the circulation, inasmuch as they destroy the neighbouring absorbent vessels. The caustic, which Fontana pre- ferred, was potassa. But, as Boyer sensibly ' remarks, every caustic, of equal strength, must infallibly have the same, effect, n« its mode of operating is that of destroying the point of irritation, viz. the seat of the ve nom. In France, liquid caustics are pre- ferred, the fluid muriate of antimony, the liquor ammonia?, or-dhe sulphuric, or nitric acid, because their action is quicker, and they more certainly penetrate to the bottom of the wound. {Traits des Mai. Chir. T. 1, p. 429.) Either of these liquids may be applied by means of a slender pointed bit of wood, which is to be dipped in it, and then introduced into the punctures, made by the fangs of the reptile. The piece of wood should be withdrawn, w r et once more, and applied again. If a drop of the caustic can be inserted, so much the better. When the bite is very narrow and deep, the caustic can- not well be introduced, before the mouth of the wound is somewhat enlarged with a lan- cet. A little bit of lint may then be wet in one of the above fluids, and be pressed deep- ly into the wound. After the caustic has produced an eschar 4 the best application is an emollient poul- tice. It is not, however, every bite of a viper, that requires local treatment, even of this degree of severity. As Boyer observes, when the wound is superficial, the viper benumbed with cold; its poison considera- bly exhausted by its having previously bit- ten other animals ; the swelling inconsider- able ; and the patient neither affected with prostration of strength, nor pain about the praecordia ; a few drops of ammonia may be introduced into the wound, and a small compress wet with the same fluid applied. Formerly, olive oil was considered, in Eng- land, one of the best applications for the bites of snakes, and its virtues were after ward extolled in France by Pouteau ; but, says Boyer, it possesses no specific efficacy, as the experiments of Hunaud and G6otfroi have decidedly proved. ( Traitd des Mala- dies Chir. T. l,p. 431.) With respect to the general treatment, if we exclude emetics, of which Dr. Mead had a high opinion, when the patient was much jaundiced the favourite medicines are cor- dials, ammonia, and arsenic. The ancients employed theriaca, Mithridates, salt, and the carbonate of ammonia. Of all stimulants, however, the liquor ammonia? is that which now obtains the greatest confidence ; or else, the eau de luce , which only differs from the fluid ammonia, in containing a small quantity of the oleum succinatum. In France, this remedy is even at the present time regarded, as having the best claim to the title of a specific for the bite of a viper {Boyer, op. cit.) In France, Bernard de Jussieu first tried ammonia in the year 1747 (see Hist, de VAcad. des Sciences , 1747 ;) since which time it has been extensively employed for the cure of the bites of vipers, both as an inter- nal and external remedy. It had, however, been highly praised by Dr. Mead at a much earlier period. A few drops of the remedy are to be ex- hibited every two hours : but. as it is very W0Li\b& boi powerful, it must always be diluted with tea, or some other drink, or the mistura cam phora?. The dose, however, must depend upon the age and constitution of the patient, and the intensity of the symptoms. Four or five drops suffice for a person of weak, delicate, irritable habit ; but twelve- or fif- teen may be given to stronger subjects, when the symptoms are violent. With am- monia, some practitioners order wine. In St. George’s Hospital, the man who was bit by the rattle-snake, kept for exhibi- tion, took aperient medicines, the liquor ammonias, aither, the spiritus ammonias, comp, opium, and other stimulants ; but without any apparent benefit. The disease followed that course which Sir E. Home has described as usual when the shock on the system is not directly fatal, and the mischief in the arm ultimately produced the man’s death. (See Phil. Trans. 1810.) From the following passage, in relation to the' bites of snakes in general, it seems that Sir Everard Home, in 1810, had no confidence in any medicines which had then been duly tried. The violent effects, which the poison produces on the part bit ten, and on the general system, and the shortness of their duration, where they do not terminate fatally, (says he) have fre- quently induced the belief, that the recove- ry depended on the medicines employed ; and, in the East Indies, eau de luce is con- sidered as a specific. There does not appear to be any founda- tion for such an opinion ; for when the poi- son is so intense as to give a sufficient shock to the constitution, death immediately takes place, and where the poison produces a lo- cal injury of sufficient extent, the patient also dies, while all slighter cases reco- ver. The effect of the poison on the con- stitution is so immediate, and the irritability of the stomach so great, that there is no op- portunity of exhibiting medicines till it has fairly taken place, and then there is little chance of beneficial effects being produced. (Sir E. Home, in Phil. Trans. 1810.) Fontana also had little faith in reputed antidotes; but it is to be noticed, that his observations refer only to the bites of*vipers. u In no country (says he) through which I passed, could I ever find any two people or persons, bit by the viper, either in the moun- tains or valleys, that used the same reme- dies. Some used theriaea alone, either ex- ternally or internally applied ; others com- mon oil ; a third set used stimulants, such as the strongest spirituous liquors ; whilst others, on the contrary, tried every different kind of sedative. In short, there is hardly any active kind of medicine that has not been tried as a cure in this disease ; while, at the same time, it is certain that, under all the varieties of application, none of the pa- tients died.” Hence Fontana concluded, that none of the remedies had any effect in curing the disease. Later observations, however, tend to raise our hopes, that a medicine is now known which really seems to possess consi- derable efficacy against Uie bite, even of a very formidable kind of snake. From some facts recorded in Dr. Russell’s History oi In- dian Serpents, on the authorities of Mr. Duf- fin and Mr. Ramsay, it appears that the Tan - jure pill, of which arsenic is the chiefingre- dient, is exhibited with considerable success in India after the bites of venomous serpents this information led Mr. Chevalier to pro- pose the fair trial of arsenic. Mr. Ireland, surgeon to the 60th regt. had formerly heard Mr. Chevalier recommend the trial of arsenic, and he was resolved to make the experiment whenever an oppor- tunity offered. On his arrival in the island of St. Lucia, he was informed that an officer, and several men, belonging to the 6Sth re- giment, had died from the bites of serpents, supposed to be the coluber earinatusof Lia- na?^. The reader will find some interesting ac count of the serpent here alluded to, in a tract, which I have lately read, entitled Mo- nographic du Trigonocephale des Antilles , on Grand Vipere Fcr-de- Lance de la Martinique, par A. Moreau de Jonnes, 8 vo. Paris, 1816. Mr. Ireland also learnt, that every thing had been tried by the attending medical men to no purpose, as all the patients had died, some in six, and others in about twelve hours from their receiving the wound. A case, however, soon came under Ml'. Ireland’s own observation, and as nothing that had been done before, seemed to have been of any service, he was determined to give arsenic a full trial. “ Jacob Course, a soldier in the York light infantry volunteers, was bitten in the left hand, and the middle finger was so much lacerated, that I found it necessary to am- putate it immediately at the joint with the metacarpal bone. “ I first saw him about ten minutes after he had received the wound, and found him in a torpid, senseless state ; the hand, arm, and breast of the same side were much swelled and mottled, and of a dark purple, and livid colour. He was vomiting, and ap- peared as if much intoxicated. Pulse quick and hard : he felt little or no paini during the operation. u The wound being dressed, and the pa- tient put to bed, I ordered a cathartic clys- ter, and the following medicine to be taken immediately. Liquor Arsenic. 3ij. Tinct. Opii, gt. x. Aq. Menth. Pip. j§iss. which was added to half an ounce of lime-juice, and as it produced a slight effervescence, it was given in that state ; this remained on his stomach, and was repeated every half hour for four successive hours. In the mean time, the parts were frequently fomented with common fomentations, and rubbed with a liniment composed of 01. Terebinth, ^ss. Liquor Ammon. |ss. and 01. Oliv. Jiss\ The cathartic clyster was repeated twice, when the patient began to be purged ; and the arsenical medicine was now disconti- nued. He had become more sensible when touched, and from that time he gradually WOUNDS C&2 recovered his faculties ; he took some nou- ner two cavities aye formed, which have rid' vishment, and had several hours sleep. sort of communication with each other “ The next day he appeared very weak, By the two pleura 1 , touching and lying and fatigued ; the fomentation and liniment against each other, a middle partition is were repeated. The swelling diminished formed, called the mediastinum. These two gradually ; the natural colour and feeling membranes are intimately adherent to each returned, and by proper dressings to the other, in front, the whole length of the ster- wound, and attention to the state of his num; but behind, where they approach the bowels, he soon recovered and returned to vertebrae, they separate from each other, his duty.” so as to leave room for the aorta, cesopha- Mr. Ireland recites about four other ex- gus, &z.c. The heart, enclosed in the peri- amples, in which arsenic was exhibited with cardium, occupies a considerable space on similar success. the left of the mediastinum, and all the rest It deserves particular notice, that the li- of the chest is filled with the lungs, except quor arsenici employed by Mr. Ireland, was behind, w here the large blood-vessels, prepared according to Dr. Fowler’s pre- nerves, tbpracic duct, and (Esophagus, are scription, which directs sixty four grains of situated. In the perfectly healthy state, the arsenic, and as many of the fixed vegetable lungs do not adhere to the pleura ; but in alkali, to be dissolved in a sand heat, and ‘the majority of subjects, at least in this the solution to be made an exact pint, so climate, who are examined after death, such that two drachms contain one grain of arse- adhesions are found in a greater or lesser jiie in solution. (See Med. Chir. Trans. Vol. degree. The disease may probably be oc- 2, p. 393, fyc.) casioned by very slight inflammation ; and IVounds of the Thorax . — The thorax is a as the surface of the lungs is naturally des- cavity of an irregularly oval figure, bounded tined to be always in close contact with the in front by the sternum, laterally by the pleura, and patients are frequently not sus- ribs, posteriorly by the vertebrae of the back, pected to have any thing wrong in the tho above by the clavicles, and below by the rax, this morbid change being often acci diaphragm, a very powerful muscle, which dentally discovered after death, in lookingfoi forms a kind of partition between the cavity something else ; it may be concluded, tha' of the thorax, and that of the abdomen. it does not produce any serious effects. The diaphragm is not stretched across, in The thorax is subject to all kinds of a straight direction, from one side of the wounds ; but their importance particularly chest to the other ; but on the contrary, depends on their depth. Those which do descends much further in some places than not reach beyond the integuments do not in others. If the cavity of the thorax be differ from common wounds, and, when opened by a transverse section, about the properly treated, are seldom followed by middle of the sternum, the diaphragm ap- any bad consequences. On the contrary, pears, on examination, to be very promi- those which penetrate the cavity of the nent and convex towards its centre, while pleura, even by the slightest opening, may it sinks downward at its edges, towards all give rise to alarming symptoms. Lastly, the points to which the muscle is attached, wounds injuring any of the thoracic viscera, At its anterior, and most elevated pajt, it is are always to be considered as placing the fixed to the ensiform cartilage, whence, de- patient in a state of considerable danger, scending obliquely to the right and left, it is From what has been said, it appears that inserted, on both sides, into the seventh rib, wounds of the thorax are very properly di- all the lower ribs, and lastly, into the lower visible into three kinds; viz. 1. such as dorsal vertebrae. According to this descrip- affect only the skin and muscles; 2. such tion, it is obvious, that the cavity of the as enter the cavity of the chest, but injure thorax has much greater depth and capacity none of the viscera ; 3. others, which in behind, than in front; a circumstance which jure the lungs, or some other viscus. surgeons ought to be well aware pf, or else Superficial Wounds of the Thorax. — Im- they will be liable to give most erroneous mediately a surgeon is called to a recent opinions concerning wounds of the chest, wound of the chest, his first care should be For instance, a practitioner deficient in ana- to ascertain, whether the w eapon has pene- tomical knowledge, might imagine that a trated the pleura or not. In order to form weapon, pushed from above downward into a judgment on this circumstance, surgical the front of the chest, could never reach the writers recommend, 1. Placing the wound- lungs, after having penetrated the cavity of ed person in the same posture in which he the abdomen. It is a fact, however, that was when he received the wound, and then no instrument could pass in this direction, carefully examining with a finger, or probe, even some inches below the highest part of the direction and depth of the stab. 2. The the abdomen, without entering the chest. examination, if possible, of the weapon, so The whole cavity of the thorax is lined as to see how much of it is stained with with a membrane named the pleura, which blood. 3. The injection of fluid into the is every where adherent to the bones which wound, and attention to whether it regur form the parietes of this cavity, and to the gitates immediately, or lodges in the part diaphragm. Each side of the thorax has a 4. The colour and quantity of the blood, distinct pleura. The two membranes meet discharged from the wound, are to be no- in the middle of the chest, and extend from ticed, and whether any is coughed up. 6. the sternum to the vertebrae. In this man- We are to examine . whether air escape* WOUNDS. boo from (lie wound in respiration, and whether there is any emphysema. 6. Lastly, the state of the pulse and breathing must be considered. In wounds of the chest, however, sur- geons should not be too officious with their probes, merely for the sake of gratifying their curiosity, or appearing to be doing something. No judicious surgeon can doubt that authors have dwelt too much on the subject of probing wounds of the abdo- men and thorax ; for they would really lead their readers to believe, that, until the wound has been traced with the finger or probe, to its very bottom and termination, surgeons are not qualified to institute any mode of treatment. The only advantage of knowing that a wound penetrates the chest, is, that the practitioner immediately feels himself justified in having recourse to bleeding and other antiphlogistic means, with the view of preventing inflammation of the pleura and lungs, which affection, if not controlled in time, often proves fatal. However, there can be little doubt, that if the nature and depth of the wound cannot be readily detected with the eye, the finger, or a probe, or by the discharge of air, or blood, it is much safer to bleed the patient than to put him to useless pain with the probe, and waste opportunities of doing good, which too frequently can never be recalled In short, generally speaking, it is better, and more advantageous for all pa- tients, that some of them should lose blood, perhaps unnecessarily, than that any of them should die in consequence of the eva euation being omitted or delayed. Almost all writers, who have taken pains to direct how wounds of the thorax should be probed, conclude with remarking, that, however advantageous a knowledge of the direction and depth of the wound may be, much harm has' frequently been done by pushing the attempts to gain such informa- tion too far. It is, perhaps, of greater im- portance to learn, by some kind of exami- nation, the extent of a wound, which does not reach beyond the integuments, or in- tercostals, than to know whether the w ound extends into the cavity of the chest. For, even when the pleura is found to be divided, if the xvound be attended with no urgent symptoms, the information is of no practical use, if we make it a rule to adopt, without the least delay, a strict antiphlogistic plan of treatment, in all cases in which there is any doubt or chance of the parts within the chest being wounded, and likely to inflame. Besides, frequently, the symptoms are more urgent and alarming than they could be were only parts on the outside of the thorax injured ; and, under such circumstances, it is manifest that a probe cannot be neces- sary for discovering that the wound extends into the chest. With respect to the injection of luke- warm water, or any other fluid, and the cir- cumstance of its regurgitation, as a criterion of the wound being only superficial, the plan i? more objectionable than the employ- ment of a probe ; for, if the liquid be pro- pelled with force, it may be injected into the cellular substance, and seem to be pass- ing through the track of the w ound into the chest, w hile, in reality, not a drop does so. Besides, is it a warrantable proceeding to try to insinuate any quantity or kind of liquid whatever between the pleura and lungs, into a situation in which it must neces- sarily obstruct the important function of respiration, and cause serious inconve- nience ? When air issues from the wound in expira- tion, there is ground for suspecting that the lungs are wounded. But I believe, that such authors as represent this circumstance as an infallible criterion of the nature of the accident, labour under a mistake ; for when there is simply an opening in the chest, with- out any injury of the lungs whatever, the same symptom may occur. The air, which is discharged through the wound in expira- tion, has previously entered the bag of the pleura through the same wound in inspira- tion. In order to remove all doubt, the pa- tient should be requested to expire, as strong- ly as he can, so as to force out whatever air may have accumulated in the chest. At the end of each expiration of this kind, care must be taken to bring the skin closely over the orifice of the w ound, and to keep it thus applied, during each following inspiration, for the purpose of preventing the external air from entering. In this way, if there be no wound of the lungs, all the air will soon be expelled ; but if it still continues to be dis- charged in expiration, the lungs must be wounded. Sometimes, an emphysematous swelling takes place round wounds of the thorax, in consequence of a quantity of air diffusing it- self in the cellular substance. In wounds, which are straight and ample, this symptom is very uncommon ; but, in cases of narrow oblique stabs, and where the lungs are wounded by the points of broken ribs, it is by no means unfrequent. (See Emphysema.) When a considerable quantity of blood flows from the wound, there is reason for conjecturing, not only that the w'eapon has penetrated the cavity of the thorax, but that some of the thoracic viscera are injured. Excepting the intercostal arteries, which run along the lower edges of the ribs, and the trunks of the thoracic arteries, all the other vessels, on the outside of the chest, are very inconsiderable. The effects of com- pression will indicate, whether the blood escapes from an artery on the outside of the cavity of the pleura ; and sometimes, the situation and direction of a wound at once denotes, that the hemorrhage cannot pro- ceed from the trunks of the thoracic ar- teries. Even the appearance of the blood, which comes from the wound, may lead to some conjectures, concerning the depth of the injury. The blood, which flow s from wounds of the lungs, is of a brighter scarlet colour, and more frothy, than that which is dis WOUNDS. 664 charged from the vessels of any other part. There can be no doubt of the lungs being wounded, when the patient is observed to spit up blood ; but, the absence of this symp- tom is not a positive proof of their being untouched, though unquestionably, a very important circumstance in the diagnosis, and, generally speaking, a correct criterion of the lungs having escaped injury. At all events, when no blood is spit, or coughed up, the lungs can never be deeply pene- trated. The state of the pulse, and that of respira- tion ought to be particularly attended to by the practitioner. Neither one, nor the other, seems altered, at least at first, when wounds do not reach more deeply than the integu- ments; but those which penetrate the cavity of the thorax, and especially such as injure the viscera, may frequently be distinguished, from the very first moment of their occur- rence, by their effects on the sanguiferous system, and the function of respiration. When the lungs are wounded, at a point where they adhere to the pleura, no air can be effused in the thorax, and the functions of those organs may, on this account, suffer less disturbance than would be the conse- quence of an equal degree of injury at some other unadherent portion of the lungs. Experience proves, that when either air or blood insinuates itself between the lungs and the pleura, the lungs become immedi- ately oppressed, the breathing is attended with great difficulty, the pulse is weak, con- tracted, and intermittent. Wounds of the integuments and muscles of the thorax, are not attended with any particular danger ; they heal with the same readiness, and by the same means, as com- mon superficial wounds in any other part of the body. When the case is a punctured, or a gun- shot wound, some writers are advocates for laying open the track of the injury from one end to the other, if its course should not be too extensive, and they then recommend dressing the cavity down to its bottom. When the track of the wound was too exten- sive, a seton was sometimes introduced. The aim of such exploded practices was to prevent the outer part of the wound from healing too soon, and. thus give time for the xvhole of it to heal in an equal degree. When a seton was used, the thickness of the skein was gradually diminished, and, after the whole of it had been removed, a slight compression was kept up for a few days, with the view of completing the cure. The French surgeons have the discredit of having brought setons into fashion in this branch of surgery, and I am particularly glad, that a late writer has well exposed the absurdity of the practice. “We find (says Mr. John Bell) the history of it to he plainly this : that as Guy de Chauliac, JPar6, and ail the older surgeons, did not know how to dilate gunshot wounds, they found these same setons useful in bringing the eschar sooner away, and in preserving an open wound ; and, as they believed the wounds to be poisoned, they took the opportunity of conducting, by these setons, whatever acrid medicines might, according to the prevailing doctrines of that .time, have any chance of correcting the-poison.” Mr. J. Bell notices, howsurprisingitistoseethe cruelty, and per- severance, with which some modern prac- titioners, particularly French, draw these cords through wounded limbs ; and when the ^roughness of such a cord, or the acri- mony of the drugs conveyed by it, produces a copious suppuration, these men are de- lighted with such proofs of their success. The setons have been introduced by the French surgeons, across the thickest parts of the limbs, along the whole length of the fore-arm, and, at the same time, frequently' through the wrist-joint. The setons have also been covered with stimulating applica- tions. Profuse suppurations, and dreadful swellings of course ensued ; still, as Mr. J Beil has remarked, these cruelties were con- tinued, till the wound healed almost in spite of the pain ; or till the coming on of very dreadful pain, great suppurations, convul- sions, &,c. made the surgeon discontinue the method, or even amputate the limb. The French have become so familiarized to setons, that they do not restrict their use to flesh wounds, they pass them quite across the thorax, across the abdomen, and even through wounds of the knee-joint. When we wish to excite inflammation, in the cavity of the tunica vaginalis, for the purpose of radically curing a hydro- cele, we either pass a seton through the part ; lay it open with an extensive inci- sion ; cram a tent into it ; or injgct some irritating fluid into it. While the animal machine continues the same, says Mr. John Bell, the same stimuli will produce the same effects, arid a seton, injection, or long tent, if they produce pain and inflammation in the scrotum, will not be easy in the chest : and, unless we can use them in the chest, with the same intentions with which we use them in the. hydrocele, (in other words) un- less we are justified in inflaming the chest, and causing an adhesion of all the parts, we cannot use them with any consistency or good sense. With regard to the cases which the French adduce in confirmation ot the good! effects of their plans, 1 am entirely of opinion with Mr. J. Bell, that the facts only prove, that ike patients recovered in spite of the setons. “ It is like (adds this author) what happened to a surgeon, who was dab- bing in the thorax with a piece of caustic which fell directly into the cavity oi the ciiest, where it caused very large suppura- tions, and yet the patient was saved, l'he patient recovered, in spite of the caustic, just as M. Guerin’s patient, and many other poor unhappy souls, who lived in spite ot the setons. One would think, that people took a pleasure in passing setons across the eyeball, the chest, the knee-joint, &c. merely to make tools stare, when the bust- WOUNDS. troll fciess might be as effectually done with an abscess lancet.” Mr. John Bell, in his usual lively style, makes the employment of tents, in wounds of the chest, seem equally ridiculous and improper. Indeed, he says, he knows of' no occasion in all surgery, in which tents can be useful, except in the single one of a narrow opening, which we desire t<> dilate, in order to g t at the bottom of the. wound ; and where either, on account of some'great artery , or the fearful temper of our patient, ive dare not use the knife. (See J. Bell on Wounds. Dis- course 2, Vol. 2.) Having hitherto been engaged, rather in pointing out what ought not to be done, than what ought, I shall next make some re- marks on the line of conduct, which should be adopted, in cases of wounds of the pa- rietes of the chest. When the wound is a common cut, the sides of the division are to be brought into contact, and maintained in this position with strips of adhesive plaster, compresses, and a bandage, until they have grown toge- ther. If the surgeon take care to relax such muscles as happen to be cut, or to be situated immediately under the wound of the integu- ments, there will rarely be any need of sutures. As cut wounds seldom or never .penetrate the chest, and there is generally no reason why they should not unite by the first inten- tion, without being followed by extensive inflammation and abscesses, antiphlogistic means should be employed with moderation. Bleeding will not often be requisite. The grand objects are, to keep the patient in a quiet state, on rather a low diet, and to hin- der him from taking wine, porter, spirits, or any other stimulating beverages. If the wound, instead of healing favoura- bly, should inflame, the treament should be regulated by the principles laid down in the article Inflammation. If it suppurate over its whole surface, but without a great deal of surrounding swelling and inflammation, one or two strips of sticking-plaster, may still be used with advantage ; for, in this way, the cavity, which must now 1 be filled^up by gra- nulations, will be rendered much smaller than it otherwise would be. Some very soft lint may be laid in the cavity of the wound, which the sticking-plaster does not entirely remove, and over the whole a pledget of some mild, unirritating ointment. No pres- sure is now proper, until the inflammation diminishes ; and if the discharge should be profuse, or the surrounding inflammation considerable, the best application would be an emollient poultice. In this state of things, the patient should also be bled, and leeches be applied near the inflamed parts. When the case is a stab, or punctured wound, the fibres of the divided parts are not simply cut, they are also considerably stretched, bruised, and otherwise injured. Hence, generally they will not admit of being united so readily, as the sides of a clean incision, made with a sharp instru- ment, However, the possibility of uniting the opposite sides of punctured wounds must depend very much on the shape of the weapon r and the suddenness, roughness, and violence, with which it was driven into the part. \ prick with a needle is a punctured wound ; so is that often made by surgeons with their lancets ; yet, these injuries do not frequently bring on violent inflammation,, and abscesses, as other wounds frequently do, which are inflicted with bayonets, and pikes. Let us suppose a man to have received a thrust of a bayonet, which has run into the skin and muscles, covering one side of the thorax : what plan can the surgeon follow, with the greatest .advantage to his patient ? Instead of laying open the whole track of such a wound with a knife, as is barbarously recommended in many of the principal works on surgery ; instead of drawing a seton through its whole course, or of cram- ming into the part a hard, irritating tent ; the practitioner should take whatever chance there may be of uniting the wound without suppuration. For this purpose, he should recollect that the great degree of violence done to the parts in punctured wounds is the reason why they are so apt to inflame and suppurate. Hence- the expected inflam - mation is to be counteracted in the very first instance ; and immediately the wound is dressed, the patient should be freely bled, and take some saline purgative medicines. With regard to the dressings, the orifice of the wound may be lightly closed with sticking- plaster, or covered with any mild superficial applications. Over and around these, the surgeon may apply linen, kept continually wet with cold water, or the liquor plumbi acetalis dilutes. As, however, many pa- tients have a strong dislike to cold applica- tions to any wounds upon their bodies, it is often necessary {^dispense with this prac- tice. The dressings are to be retained with a roller ; but it is not to be tight, as pressure is more likely to do harm, than good. Thus the inflammation of the wound will be moderated ; the extravasa- tion of blood prevented-, the chance ofunkm by the first intention taken ; and all p^rfM operations avoided. And, nothing is morlf certain than the fact, that, if antiphlogistic means be strictly employed, many stabs heal without abscesses, or any very severe symp- toms, when no hope could be entertained of their doing so under other treatment. But, if suppuration should happen, and a col- lection of matter take place, would the patient suffer more, or -be put into greater danger, by having a proper depending opening, of just sufficienffsize, now made into the abscess in an eligible place, than if he had submitted to have the formidable operation of laying open the whole extent of a stab, performed in the first instance ? In short, will he suffer half so much, be half so long in getting well, or have to encounter half the danger ? With all this advantage, he will have taken a certain chance, which attends all these cases, if the wonnd be- WOUNDS. 050 coming united by what is called the first intention, that is to say without any suppu- ration. I need not enlarge upon this subject, but refer the reader to what has been said in the preceding columns on the subject of Punctured Wounds, and to the treatment of abscesses, in the article Suppuration. Gun- shot wounds, merely injuring the parietes of the chest, are to be treated according to principles elsewhere explained. (See Gun- shot Wounds.) Of Wounds penetrating the Cavity of the Thorax . — Penetrating wounds of the- chest are always dangerous, and claim the utmost attention of the practitioner. I shall first treat of such wounds as enter the cavity of the thorax, but without injuring the viscera. In the healthy state, the lungs so complete- ly fill the thorax, that, both in inspiration and expiration, they are always in close contact w«h the pleura ; and whenever air, blood, or any other matter, insinuates itself between the pleura costalis and pleura pulmonalis, more or less oppression and difficulty of breathing immediately take place. In all wounds attended with a division of the pleura costalis, and occurring in a situation where there happens to be no adhesion be- tween this membrane and the lungs, some of the external air, ora small quantity of blood, or both, can hardly fail to get into the cavity of the thorax. If one of the intercostal ar- teries be wounded, and the external orifice be very narrow, the blood furnished by this vessel may pass into the chest, and immedi- ately produce oppression of the breathing, and other symptoms of pressure on the lungs. Of what is to he done in this case, l shall presently speak. When a wound is known to have entered the pleura, and there is no symptom leading to a suspicion that the lungs, or any large vessel, is wounded, the injury is to be dress- ed according to common principles, and the more superficially the better. Authors also usually direct us, just before we close the opening, to tell the patient to make a deep inspiration, for the purpose of expelling as much of the air as possible, which may have passed into the cavity of the pleura. At the end of such inspiration, the edges of the wound in the skin are to be brought together, and kept so with sticking-plaster, com- presses, and a roller. The other indications are to prevent inflammation of the pleura and lungs by rigorous antiphlogistic reme- dies, particularly bleeding, which should be copious, and repeated as circumstances may require. Penetrating wounds of the chest may be complicated with some of the following cir- cumstances: 1. Foreign bodies. 2. Injury of one of the intercostal arteries. 3. Pro- trusion of a portion of the lungs. 4. Em- physema. 5. Extravasation of blood in the thorax. 1. Almost all these wounds occasion pain and difficulty of breathing. Many of them are also followed by an emphysematous swelling around the w ound ; the patient fre- quently coughs up blood : and after having had for some time a small, contracted, irre- gular pulse, with a pallid countenance and cold extremities, he is too often seized with severe fehrile symptoms, the effect of inflam mation of the lung3 and parts within the chest. These symptoms should be counter acted by bleeding, a very low regimen, open ing saline medicines, the use of leeches, or cupping, and the strict observance of qui- etude. If such indisposition should con- tinue longer than a few days, without dimi nation, writers inform us, that there is ground for suspecting that they depend upon the presence of some foreign body. However, it may be doubted whether Sabatier’s advice, iramediaiely to make search after the extra- neous substance, is proper under these, cir- cumstances. For tny ow r n part, I cannot think the symptoms above related by any means unequivocal, and even were they so, the practice would -dill be questionable. (See Medecine Opiratoire, Tom. 2, p. 244.) Sabatier has quoted the two following ca^es, for the purpose of showing what may be attempted in these cases. — “ A man, twen- ty-seven years of age, was struck very vio- lently with a knife on the outer part of the fourth true rib. Simple dressings were ap- plied tor the first few 7 days; but a considera- ble coughing and spitting of blood ensuing M Gerard was consulted, wdio found, that the symptoms depended on the presence of a piece of the knife, which had pierced the rib, and was projecting some way into the thorax. So little of the foreign body w 7 as on the outside of the rib, and it was so fixed in the bone, that it could neither be extracted with any kind of forceps, nor even moved in the least with a leader, mallet, he. Al- though the only expedient seemed now to be that of sawing orcutting out the portion of the rth, Gerard conceived that an attempt might first be made to extract the foreign body, by pushing it from within outward. For this purpose, having put a steel thimble on his index finger, he introduced it into the cavity of the thorax, and thus succeeded in pushing out the piece of the knife. A spicula of the bone was afterward felt , but it wa^too firmly connected with the rest of the i ib to admit of being completely taken out. Gerard was absurd enough to surround the whole rib at the splintered part with a li- gature . . To these ingenious proceedings, as the French term them, was imputed, not only the cessation of all the bad symptoms, but a speedy recovery. (See la Faye's Notes to the Trait 6 des Operations de Dionis.) An officer was shot in the left side of the chest. The ball entered about where the bone and cartilage of the seventh true rib unite, and came out in the situation of the angle of the same bone, which was broken in tw 7 o places. The posterior part of the first false rib was also broken Incisions were made, which enabled the surgeon to take away several splinters of bone, and fa- cilitated (that mischievous French practice) the introduction of a seton. Soft mild dress ings were applied. The patient was bled twenty-six times, with the view of relieving WOUNDS. the fever, difficulty of breathing, and spitting of blood. On the fifth day, suppuration commenced, and the seton could be easily drawn. In about a fortnight, the patient’s sufferings considerably abated, and he passed som* of the ensuing days in a tolerably easy state. Circumstance*, however, made it necessary to move him to another place, and on the twenty-fourth day, he had a bad night ; febrile symptoms came on ; and the discharge was not of its usual consistence. He was bled twice more, and hia critical state led the surgeon to examine the wounds again. On passing a finger into the posterior wound, a foreign body was felt, an i easily extracted. It was a piece of the patient’s coat. A spicula of bone was also felt more deeply lodged, which required the wound to be dilated. Partial relief followed the re- moval of these extraneous substances. On the thirtieth day, the bad symptoms recurred, two more bleedings were practised, and as fears were entertained that ike seton zvas doing harm , it was suppressed. The pa- tient now first made complaint ot feeling something which pricked him, in a deep situ- ation between the two openings of the wound. It was therefore determined to di- vide all the parts intervening between the two orifices, and occupying an extent of seven or eight inches. Guerin cut the parts between the two ribs, from within outward, under the guidance of his finger introduced into the posterior wound, care being taken not to cut near the lower edge of the upper rib. In this way, the whole track of the ball was laid open, and in the middle of it. a very sharp splinter was found, projecting into the substance of the lungs. It was re- moved, and the wound dressed with simple applications. From this day all the bad symptoms ceased. (06s. de Guerin in Mem. de I’Acad. de Chir. T. 2 ; 41c.) Mr. John Bell has taken notice of the pre- ceding case ; he observes, that some of Gue- rin’s steps were bold and good, as well as successful; but that the employment of the seton was wrong. The example teaches us several important circumstances : 1. The propriety of making very free dilatations for the extraction of splinters of bone. 2. The utility of repeated copious bleedings, which in the above case, indeed, had the greatest effect both in preventing such hemorrhage in the chest as would probably have produced suffocation, and also in averting a degree of pulmonary inflammation, which would have proved fatal. Mr. John Bell judiciously condemns the seton : “ Had M. Guerin (says he) been asked what good it was to do, it would have been difficult for him to have invented even a plausible apology for the practice which, if it was not doing good, could not fail to do harm. Was this seton nece sary for keeping the wound open ? No, ureiy ; for the wound could not have closed while il was irritated and kept-in suppuration by splinters of bone, and a piece of cloth within the breast. Was it to draw the piece of cloth out ? Surely, in the course of twentr days, a piece of cloth Vo;,. II ' S3 657 would have had some chance at least of be- ing floated towards the wound, either by the natural flux of the matter, or by the help of a mild injection. Was it uspful in support- ing the discharge ? This would have been a sore question lor M Guerin ; for it support- ed the suppuration only by inflaming the chest ; and where inflammation of the chest, or high cough, or bloody expectoration, or a profuse discharge, were the chief dangers, a great seton could hardly be a comfortable inmate in the breast. 1 think one might very boldly promise to produce bloody ex- pectoration and terrible cough, profuse sup- purations, and oppression, to any degree, by drawing such a cord across a sound thorax.” Mr. John Bell next censures M. Guerin for not having discovered the pricking piece of bone before the thirty-eighth day; a disadvan- tage which he partly ascribes to the seton, the pain of drawing which across the chest deadened every lesser pain, and, consequent- ly, the patient could not feel the trilling pricking of the bone, (ill his greater suffer- ings from the seton were allayed. “ In short, (says Mr. John Bell,) M. Guerin passes a a great strap of coarse linen across the cavi- ty of the chest, and when it causes inflam- mation, he thinks to subdue it by bleeding ; when M. Guerin continued for thirty days drawing a coarse seton through the breast every morning, and bleemng for the cough every night, what did he do but raise inflam- mation with his left hand, to show how well he could cure it w ith his right ?” (See John Bell on Wounds , Vol. 2, p. .36 — 38.) The liability of wounds of the chest to be complicated with the lodgement of foreign bodies, is a circumstance of which the prac- titioner should ever be mindful. u In the examinations of the bodies of soldiers who have died from these injuries, (says Dr. Hennen,) I have frequently found pieces of wadding or clothes, spiculae of bone, and balls, and, in one case, some charpie used as a dressing ; either loose in various parts of the lungs, or lying in sacs, which the exer- tions of the constitution to free itself had thrown round them by the medium of the coagulating lymph. Iu the more fortunate few who have recovered, these matters have been discharged from the wounds, or ex- tracted from them by the surgeon. In some lucky cases, they have been ejected by the convulsive efforts to cough, which their irri- tation has occasioned.” ( On Military Sur- gery , Ed. 2, p. 367 ) For an account of the dexterity with which Larrey has sometimes traced balls in ihe chest, and extracted them by bold operations, I must refer to his valua- ble writings. (See Mem. de Chir. Mil . T. 4 ,p. 250, fyc.) Balls have sometimes lodged and remained encysted in the lungs for upwards of twenty years, without the health beins; at all disturbed by their presence (See Percy, Manuel , fyc p. 125 ; Boyer , Trait 6 des Mai. Chir. T. 7,p. 310, fyc.) 2. When one of the intercostal arteries is wounded by a narrow oblique stab, the ac- cident cannot at first be known. In this case, the blood commocly make? its way WOUNDS. 6-58 into the cavity of the chest, where it causes a more or less considerable extravasation. But when the wound is ample, and direct, the effused blood, which has all the charac- ters of arterial blood, leaves no doubt con- cerning the injury of an intercostal artery. However, if any uncertainty prevail, it may easily be dispelled, by introducing a finger into the wound, and making pressure with it on the lower edge of the rib, which cor- responds to the vessel suspected to be in- jured. Gerard proposed to stop hemorrhage from the intercostal artery, by means of a liga- ture. His plan was to enlarge the external wound, as far as the upper edge of the rib, corresponding to the wounded intercostal artery, and then to introduce into the chest a common curved needle, armed with a ligature, to which was attached a dossil of lint. The needle was passed behind the rib, rather higher than the superior edge of the bone. The point of the instrument was then pushed from within outward, and brought out through the external wound, together with the ligature. When the dossil had come into contact with the artery, the two ends of the ligature were tied over a thick compress, placed on the outside of the rib. In this manner, the bone was sur- rounded with the ligature, and the artery compressed. Goulard, of Montpelier, having found dif- ficulty in passing a common needle, whose shape little corresponded to the track, through which it had to pass, being curved towards its point, and straight towards the eye, invented one expressly for this opera- tion. He also objected to the common bent needles, as he conceived that they might wound the lungs with their sharp points and edges. Goulard’s needle formed three-fourths of a circle, and was fixed on a long handle, which facilitated its introduc- tion. The eye, in which the ligature was put, was situated near the point, which was a little blunted, and the ligature lay in a groove, in the convexity of the instrument. When the needle had passed through the intercostal muscles, and its point had made its appearance over the rib, which was above the artery, the ligature was untied, and held, while the needle was withdrawn at the place where it had entered. The ligature was then tied, as in Gerard’s me- thod. It was afterward thought, that com- pression might answer better than the fore- going use of the ligature. Lottery, professor of anatomy in the university of Turin, con- structed, for this purpose, a steel plate, which is described, and engraved in the second volume, 4to. of the Metnpires de 1’Acad. de Chir. This plate was narrow at one end ; broad at the other ; and curved in two directions at its narrow part, where there were some holes, by means of which a compress for the artery was fastened ori the instrument. The broad end of the plate bad two long parallel slits, through which a riband was passed, with which the instru- ment was secured. When the wound, corresponding to the intercostal artery, was sufficiently extensive in the transverse direction, the narrow, bent end of the instrument was so introduced, that the lower edge of the rib above was placed in the concavity of the curvature, while the compress acted on the edge of the bone, and, of course, 011 the artery. The rest of the instrument appiied itself to the side of the thorax, in which situation it was fastened. When the wound was not ample enough, a sufficient dilatation of it was first made for the introduction of the instrument. Quesnay employed a piece of ivory, which he covered with lint, Lc. and then intro- duced within the chest. The instrument was then drawn from within outward, by means of a riband, and thus the necessary compression was produced. Quesnay’s plan is somewhat like that in- vented by Lottery. But, to have introduced the compress entirely into the thorax, to- gether with the ivory, which was the basis of it, and then to have drawn the contri- vance from within outward, as was probably intended, a very large wound would have been indispensable. This was also one of the many strong objections to Lbttery’s instrument, which, in fact, could only be employed when there was a free and ample opening. Belloque, seeing the inefficacy of all the compressing means used before his time, and their inconveniefices, invented an in- strument, which, he says, is calculated for making proper pressure, and following the motion of the ribs, without hindering the escape of extravasated blood. The machine is engraved, and described, in 2 T. of Mem. de 1’Acad. de Chir. 4to. It is composed of two plates, which are wadded, and capable of being brought towards each other by means of a screw. This instrument, as Sa- batier observes, may indeed answer ; but it is complicated and awkward, and its utility is founded on the supposition of the wound being larger, than wounds are, which are made with common weapons. Justly averse to any unnecessary multi- plication of surgical instruments, modern practitioners reject all particular contrivan- ces for stopping hemorrhage from the inter- costal arteries. Indeed, as the accident is very rare, it is probable, that, if the best in- strument possible were devised, it would hardly ever be at hand, when required. A common dossil of lint (says Sabatier,) fastened to a strong ligature, and introduced between the two ribs, or even quite into the chest, and then drawn, from within out- ward, like Quesnay’s compress, would fulfil every desirable purpose. The ■ external wound should then be covered with simple dressings, and a bandage applied round the body. The patient should be freely and repeatedly bled, and treated on the most rigorous antiphlogistic plan. Professor Assalini joins all the best, mo- WOUNDS. 659 dern surgeons in reprobating the introduc- tion of the preceding contrivances and ex- traneous substances into the chest, in order to stop hemorrhage from the intercostal ar- tery. All these methods, he remarks, .are calculated to excite a dangerous degree of inflammation in the chest. Hence he pre- fers simply cutting the artery across, so as to allow it to retract, and if this plan fail, he recommends the wound to be elosed. Should the blood find its way into the chest, it is true, the consequences will be serious, but not fatal ; and, if the symptoms require it, the operation of empyema may after- ward be done. A small quantity of effused blood, however, may be absorbed, and no such proceeding be requisite. ( Manuale di Chirurgia , p. 58, 59.) Dr. Hennen conceives, that whenever the tenaculum can be used for an injured inter- costal artery, the practice should be adopted. He states, that cases are reported in which the vessel was thus secured ; but that he has never seen the method adopted himself. “ Unfortunately, (says he) we but too often are disappointed in finding the source of the hemorrhage, and here judicious pressure is our only resource. In some very slight cases, I have used the graduated compress with success; but if the sloughing is exten- sive, nothing but the finger of an assistant, relieved as often as occasion may require, aud pressure direct upon a compress placed along the course of the vessel, or so dispo- sed as to operate upon its bleeding orifice, will be of any avail. (, Military Surgery, Ed. 2, p. 377.) 3. The protrusion of a portion of the lungs, in consequence of wounds penetra- ting the tfhest, is a very unusual case : but there are some instances recorded by wri- ters : and one case l attended myself after the battle of Waterloo. Sehenckius relates an example, taken from Rolandus, The latter was called to a man, who had been wounded in the thorax, six days before. A portion of the lungs protruded in a state of mortification. Rolandus extirpated it, and the patient soon recovered. Tulpius has recorded a similar fact. A man received an extensive wound, just be- low his left nipple. His naturally gay dis- position, however, led him to neglect the injury; and on the third day a piece of the lung3, three inches in length, protruded. The patient went to Amsterdam, whence he was distant two days’ journey, for the pur- pose of receiving succour in one of the hos- pitals of that city. The protruded piece of lung, which was already mortifying, was tied, and cut off with scissors. It weighed three ounces. The wound healed in a fort- night, and the patient experienced no com- plaint afterward, except a slight cough, with which he was occasionally troubled. He survived the accident six years, leading a wandering, drunken life. After death, no- thing particular was observed in the thorax, except that the lungs had become adherent to the pleura, in the situation of the wound, Hildanus relates another case : a man wa? wounded with a knife, between the fifth and sixth ribs, near the sternum. As a piece of lung protruded through the opening, and had a livid colour, it was extirpated with the actual cautery. The wound was then dilated, and the ribs kept apart, with a wooden wedge, under which plan, the por- tion of lung, girt by the opening, shrunk within the chest. The patient was soon completely well. A fourth example of a protrusion of a piece of lung through a wound in the tho- rax, is among the cases recorded by Ruysch. The servant of a seafaring man was wound- ed in the anterior and inferior part of the chest, and was immediately attended by a surgeon, who mistook the protruded piece of lung for a portion of omentum, and ap- plied a tight ligature round it. Ruysch, who was consulted, soon detected the mistake which had been made, but he delivered his opinion, that the wound would heal very well, as soon as the tied piece of lung was detached. The event justified his prognosis, and the patient recovered. When the protruded portion of lung is sound, the reduction ought to be made without the least delay. It should be done on the same principles as those on which protruded pieces of intestine, or omentum, are reduced. (See Wounds of the Abdomen .) A recurrence of the accident is to be pre- vented by closing the wound, and placing a compress over it. But when the piece of lung is already in a mortified state, in con- sequence of the constriction which it has suffered, or when its large size prevents re duction, Sabatier is of opinion, that the only resource is to extirpate the part, after apply- ing a ligature round its base. If the latter step were not taken, a dangerous hemor- rhage might follow, or even an extravasa- tion in the thorax. (Midecine Optratoire , Tom. 2, p. 224.) However, the practice recommended by Sabatier appears ques- tionable in the instance of mortification, be- cause the dead part will naturally be thrown off by a spontaneous process ; and when the wound is too small to allow the part to be returned, its dilatation might be more adviseable than the removal of a consider- able portion, or even any, of the lung. After the battle of Waterloo, I had a pa- tient with a protrusion of a piece of lung, four or five inches in length. The part was much bruised, and coitld not be easily re- duced. I therefore applied a ligature round its base, and cut it off. Previously, how- ever, I made an incision in it, in order to ascertain ^whether it would bleed freely, which being the case, induced me to use a ligature. I was afterward informed by my friend Mr. Collier, that the man died. 4. Emphysema is another symptom with which penetrating wounds of the chest are frequently complicated, especially when they are small, and indirect. When such wounds are small, and not straight in their course ; when their track is rendered im- pervious either by change in the situation of the muscles, the swelling of the parts. WOUNDS. liOU clots of blood, or any extraneous substan- ces ; air may insinuate itself into the cellu- lar substance, so as to cause a great deal of tumour and distention. Emphysema is easily distinguishable by the tumefaction of the part affected, without any pain, or change of colour in the skin, and by the crepitation which is perceptible on pressing the air from one part of the cellular sub- stance into another. Emphysema may take place, where the lungs are not wounded, but in this case it can never be of much ex- tent. Here the emphysematous swelling is caused by the air, which insinuates itself into the cavity of the thorax through the wound, during the first inspirations which follow the accident, and the same air is expelled in the subsequent acts of expira- tion. But when the lungs are wounded, the emphysema arises from the escape of air from those organs, during inspiration, first into the cavity of the thorax, and thence, through the inner opening of the external wound, into the cellular substance. I should have deemed it unnecessary to have said any thing in this part of the work, on the present subject, and have contented myself with referring to the article Emphy- sema, were not the cause of this symptom rather perplexing, and did I not hope that the following extract from Sir A. Halliday’s publication will tend to facilitate the com- prehension of these cases. This gentleman menlions the following circumstances, under which air may escape from the lungs, or emphysema arise. 1st. u An injury or disease of the pleura pulmonalis, causing a wound or ulceration of that membrane, and thus allowing the air to escape from the lungs, as in oblique ex- ternal wounds, where the outer opening, and that of the pleura costalis have healed, or closed up, and in ulcers of the surface of the lungs. 2dly. “ The pleura pulmonalis, and pleura costalis, may be wounded or ulcerated when there is no external opening, as when the ends of fractured ribs penetrate through both into the substance of the lungs; and it is from this accident, fcc. that emphysema most commonly takes place. 3d!y. “The common- integuments of the parietes of the chest, the intercostal muscles, and the pleura costalis may be wounded, while the plura pulmonalis and the lungs remain uninjured, so that the air admitted from without, and collected in the cavity of the thorax, may be pressed into the cellular membrane, so as to occasion emphysema.” The same writer remarks, “ that the lungs in the thorax have often, and not unaptly, been compared to a bladder in a close pair of bellows; but if we suppose the bellows to be divided into two compartments, and each of these to contain a bladder, which mutually communicate with each other, and with the external air, by means of a tube which is exactly adapted to the nozzle of the bellows, arid which admits the air only into the cavity of the bladders, and not into the space betwixt the bladders and bellows. we shall then have a perfect representation of the mechanical structure of the thorax The bellows will represent the thorax, divi- ded in the middle by the mediastinum ; the bladders will represent the lungs of the right and left sides; and the tube, which com- municates with the bladders and with the external air, will represent the trachea. The only thing which is wanting to render this mechanical representation perfect* is, that the bladders should exactly fill (he bellows, so as to leave no air betwixt them and the bellows.” It is explained by Sir A. Halliday, that when the handle of the bellows is lifted up, the bladders become filled by the external air, which rushes in through the tube which communicates with both of them. When the handle is depressed, the air is expelled again. In the like manner the lungs are filled with air, and emptied again when the capacity of the chest is enlarged by the inspiratory rnus° cles, and then diminished by the expiratory ones. When emphysema arises from a wound, or ulceration of the pleura pulmonalis, on one side of the thorax, the case is nearly the same as if an opening were made in one of the bladders, which opening would form a communication, as the same gentleman ob- serves, with the bellows and bladder on one side. It this should happen while the handle of the bellows is depressed, no sooner is the handle raised, than air rushes into the space betwixt the bladder and bellows, and on keeping up the handle a little while, the bladder will become quite collapsed, and the place which it occupied, while distended, will now be occupied by the air. If now, says Sir A. Halliday, u we attempt to force out the air, by depressing the handle of the bellows, we shall find that this cannot be done ; for there is no direct communication between the bellows and the external air ; and as the effused air presses equally on all parts of the collapsed bladder, it cannot es cape through it.” When the thorax is expanded in inspira- tion, the pressure is taken off the surface of the wounded lung, and the air which now enters this organ, instead of distending its cells, passes through its wound into the space between the pleura pulmonalis, and pleura costalis. The lung will, indeed, be partially expanded, as long as inspiration on that side goes on ; the more so, the smaller its wound is. At every expiration, however, when the thorax is diminished, the effused air will be compressed against the wounded lung; but none of the air which has escaped can re-enter the lung again ; “ because (as the preceding writer accurately remarks) the whole of the air contained in the lung, must be forced out, and then (lie pressure (of the air) against every part of the collapsed lung being 6qual, will prevent its separating any part, so as to make a passage for itself into the trachea.” Thus fresh air accumulates at every inspiration in the space between the pleura?, while none can escape from the same situation during expiration, and the quantity W#UNDS 661 accumulated will, at last, eqaal that which is received into the other lung, during the most powerful inspiration. When the pleura pulmonalis, and pleura costalis are both wounded, the same effusion of air between them continues from the above-mentioned causes, till the lung collap- ses. Vyben an attempt is now made to ex- pire, the injufed side of the thorax must con- tinue distended, notwithstanding every el- fort of the patient. In this expiratory act, however, if the capacity of the thorax be diminished, and the air compressed, a part of it finds its way through the wound in the pleura costalis, into the common cellular, substance of the parietes of the chest. The passage of air into the cavity of the thorax during the inspiration is, as Sir A. HaUiday observes, now more easy than the return of that already effused in the cellular membrane, and consequently, the subcuta neons emphysema continues to increase with a rapidity which is remarkable, as long as the patient lives. To explain the origin of emphysema, in cases of wounds, which only enter the chest, and do not injure the lungs at all, this writer has recourse to the simile of the bellows and bladders. Were an opening made into the bellows, without injuring the contained bladders, and the access of air by this open- ing more free than that by the nozzle, com- municating with the cavity of the bladder, more air would enter by the opening, than by the pipe, on the handle being raised, so that the bladder would not rise as usual, when no opening in the side of the bellows existed. If the latter opening be smaller than that of the pipe, the bladder will only be par- tially filled, and on depressing the handle of the bellows, the air contained in the bladder, and that between the bladder and the bel- lows, will be expelled in the same propor- tion to each other, as that in which they were formerly filled. This process would continue to go on in the same way, did not the bladder naturally collapse more and more from its gravitation. Let us now stop the mouth of the pipe, while the handle of the bellows is raised, and the bladder par- tially filled. On trying next to depress the handle, it results, that as no air can escape from the pipe, the air contained between the bladder and the bellows must be first evacuated, while that contained in the blad- der of the sound side, will be forced into the bladder on the injured side, and either distend it, so as to rupture it, or cause it to protrude. Hence, in the case of a wound penetra- ting the chest, without injuring the lungs, if the air can enter more freely by the wound than by the trachea, more of it will enter, in the act of inspiration, into the cavity of the thorax, than into the lungs. On the contrary, when the opening of the wound is not so large as that of the tra- j chea, less air will enter the thorax than the lungs. In the expiration, the air will be forced from the two different situations, in pro- portion to the quantity which enters each of them in inspiration, and no air at all would accumulate in the thorax, did not the lungs always tend to collapse from their gravitation. Should, however, the patient, in making an effort to expire, contract the glottis, the air contained in the lungs of the sound side, may be propelled into the bronchia and air-cells of the lungs, on the same side as the wound, so as to distend them, and even make them protrude at the wound. Dr. HaUiday remarks, that such a pro- trusion often happens, when wounds are made in dogs, and has been erroneously adduced as an argument against the col- lapse of the lungs, when an opening is made into the thorax of the human subject. (See Obs. on Emphysema , by Sir A. HaUiday, 1807.) For information concerning the treatment of this affection, see Emphysema. 5. I have already noticed, that wounds of the thorax may injure one of the intercostal arteries, and when the blood cannot flow outward, it may be extravasated in the chest. The same consequence may follow wounds of the pulmonary vessels, those of the heart, or of the heart itself. And here I may take the opportunity of remarking, that sometimes wounds of the heart do not prove instantaneously fatal. A case in which a bayonet passed through the colon, sto- mach, diaphragm, part of the lungs, and the right ventricle of the heart, and yet the pa- tient lived nine hours after the receipt of the injury, is recorded by Dr. Babbington. (See Med. Records and Researches , Lond. 1798 ; also a case by Ckastenet in Jour, de Med. Mil. T. 2.) In almost all cases, however, such injuries prove instantly fatal ; and the same remark will extend to cases of hemor- rhage from vessels above a certain size, but when they are less considerable, the pa- tient may live for a greater or less time, and receive the aid of surgery. The following are the symptoms which denote an extravasation of blood in the thorax. The patient feels great oppression, and such uneasiness as will not let him long continue in one position. Unless he bend his body very much forward, in which posi- tion, the diaphragm is relaxed, and not so much dragged by the weight of the extrava- sated fluid, he feels great difficulty in stand- ing or sitting up. When the thighs are bent, the patient can lie with tolerable ease on his back ; be is also not averse to lying on the side, on which the wound is situated ; but he cannot place himself on the opposite side, without feeling very acute pain in the situation of the mediastinum. His respiration is short, frequent, and in- terrupted by sighs ; his veins become emp- ty ; a cadaverous paleness spreads over his countenance ; his extremities become cold ; a viscid perspiration covers his neck and temples; his teeth chatter; his pulse be- comes weak ; and if, as most frequently happens, the lungs are wounded, he spit?- WOUNDS. up frothy blood, end air issues from the wound. Though one might suppose (he above class of symptoms always attendant on a considerable effusion of blood in the thorax, this is not the case. Wounded persons have been known to die of such an extrava- sation, whose respiration was tolerably free, and who did not complain of suffering more inconvenience in one posture than another. Sabatier says, that several facts of this kind have fallen under his own observation. Olher wounded persons, also, who suffered most of the complaints ascribable to extra- vasations of blood in the thorax, have been cured by ordinary means. Mery gives an account of a young man, wounded in the anterior and superior part of the chest, about two o’clock in the morning, who had such difficulty of breathing, and fever, five hours afterward, that an extravasation was sup- posed to exist, and Mery was thinking of making an opening for its, evacuation. A tumour near the great pectoral muscle, pre- senting neither t lie feel of fluctuation, nor that of emphysema, made him suspend his decision. The tumour was dispersed by bleeding, and the application of compresses, dipped in a mixture of spirit of wine and water. However, even the assemblage of the above symptoms did not deceive Petit. Having been requested to assist at an ope- ration, which was about to be done on a wounded man, about whose armpit, pecto- ralis major, and latissimus dorsi muscles a prodigious emphysematous swelling had ta- ken place ; whose respiration was painful and difficult ; and who spit up frothy blood ; Petit gave it as his opinion, ihat it was unne- cessary to make an opening into the chest. He thought it would be sufficient to enlarge the wound, which was at a little distance from the armpit, near the edge of the latis- simus dorsi, so as to give vent to the effused air. This advice was followed, th§ emphy- sema soon disappeared, and the patient re- covered. The equivocal nature of the symptoms of extravasations of blood in the thorax, has induced practitioners to pay the most scru- pulous attention to every circumstance at- tendant on these cases. In several instan- ces, Valentin remarked, that an ecchymosis occurred, at the angle of the false ribs, and spread towards the loins. The ecchymosis is described as being of a clear purple colour, like the spots which sometimes form on the abdomen, a little while after death. In a case, in which most of the symptoms of extravasation were combined with the above sort of ecchymosis, Valen- tin advised a counter-opening to be made. The advice was overruled, and the patient soon afterward died : more than six pints of blood were found extravasated in the thorax. Sabatier remarks, that we cannot too highly applaud the zeal of those practi- tioners, who endeavour to dispel the doubts which still prevail in several parts of sur- gery. At the same time, he thinks, that ail who take interest in the improvement of this science, should endeavour to ascertain the truth of any new observations which are offered. Hence, he deems it proper to relate a case which was communicated to him by M. Saucerotte (the father,) an emi- nent military surgeon, and which shows that the ecchymosis, observed by Valentin, is, at least, not invariably attendant on ex- travasations of blood in the chest. A light- horseman, who had received a thrust with a sabre in the right side of the thorax, above the tendon of the pectoralis major, appeared to be going on very well for the first four days after the accident. On the fifth, he complained of difficulty of breath- ing, uneasiness, and an inability of lying on the left side, without aggravating his com- plaints. He complained of a great deal of pain in the region of the liver, and at the top of the shoulder. His pulse was small and contracted, and rather hard than weak. The right side of the chest seemed larger than the left. On the eight and ninth day, the symptoms became more urgent, and the patient found no ease, except in leaning on his right side, and supporting himself on a chair, placed across his bed. This assem- blage of symptoms indicated an extravasa- tion of blood in the right cavity of the thorax ; but as the ecchymosis, which Va- lentin has described, was not apparent, doubts were entertained about the real na- ture of the case. When a counter-opening was made on the dead body, a pint of pu- trid blood flowed out. When the surgeon feels assured, that an extravasation of blood in the thorax has really occurred, and the symptoms are very urgent, the discharge of the confined fluid appears to promise benefit. However, be- fore the operation is done, the revived state of the pulse, the return of warmth in the extremities, and the cessation of great faint- ness, ought to denote, that the hemorrhage no longer continues from the vessels ; for, if this be not the case, a fresh quantity of blood must soon be extravasated again, and the patient die exhausted. Authors mention five methods of dis- charging blood from the thorax ; viz. 1st. By placing the patient in a posture, which favours the escape of the blood. 2dly. By introducing a syringe for the purpose of sucking it out, or a mere cannula, through which it is to flow. 3dly. By enlarging the wound. 4thly. By employing injections. Stilly By making an opening in a depend- ing part of the thorax. 1. Success cannot be expected from merely placing the patient in a posture, which is favourable to the escape of the ex- travasated blood, except when the wound is situated at the inferior part of the chest, and is large and direct in its course. Parc successfully adopted this method in the case of a soldier, who was stabbed in three places with a sword ; one of the wounds, which entered the chest, being situated under the right nipple. The man was fire* WOUNDS Otje dressed by a surgeon, who made several sutures. The patient was soon afterward attacked with considerable difficulty of breathing, fever, coughing, spitting of blood, and acute pain in the side. Par6, who was consulted the next day, suspected that an extravasation had happened ; consequently he cut out the sutures, and placed the pa- tient in a position, in which his feet were much more raised than the head. Pare also recommended him to hold his breath, and then introduced his finger into the wound, in order to take away some clots of blood, which appeared at its orifice. By these steps, the discharge of seven or eight ounces of fetid coagulated blood was effected. 2. The idea of drawing out of the thorax extravasated blood with a syringe is rather ancient. The pipes of all syringes, for this purpose, should have blunt ends, lest they injure the lungs. Mere tubes, containing a stilet, have also frequently been employed. Scultetus relates a case, in which an instru- ment of the latter sort was successfully employed. No syringe, nor any suction with the mouth/ was requisite. It was found necessary merely to introduce the tube, and then withdraw the stilet. Lamotte used only a simple cannula, which he introduced into the centre of the extravasation. Then having placed the patient in what he conceived to be the most favourable posture, and requested him to hold his breath, he drew &ff the collection of fluid. The cases numbered 216, 217, 218, show the success which attended this me thod. Although it might also have answered very well in case 219, Lamotte saw that the high situation of the wound w ould not have allowed all the blood to be discharged, and therefore he made a counter-opening. Thus the thorax was completely emptied, and a recovery ensued. When a cannula is employed, authors recommend it to be introduced every day till the bad symptoms cease, and no more fluid escapes through the cavity of the instrument Alter having given vent to blood, it allow's a bloody se- rous fluid to escape, and at a later period pus, w hich becomes of a thicker and thicker consistence, the nearer the patient is to a recovery. 3. The cases in which a wound, compli- cated with an extravasation in the chest, should be dilated, are those in which the situation of the opening is favourable to the escape of the blood. The operation is performed with a curved bistoury, and a director. The integuments, and external muscles, are to be divided in a perpendicu- lar direction, and the intercostal muscles in a line parallel to the ribs. Care is also to be taken not to cut loo near the lower edge of the upper rib, lest the intercostal artery be wounded. Dionis practised such an operation on a soldier, who was wound- ed at Befort, in 1703, with a sword below the right nipple, whereby a direct opening was made into the thorax. When the ex- travasated fluid had been let out, Dionis made the patient lie on the wounded side during the night, and in proportion as the blood continued to be thus evacuated, the breathing became free from oppression. 4. The methods, above explained, may be of use when the blood retains its natural state of fluidity; but, when it is coagulated, as often happens, they can be of no avail. In tins circumstance, most authors direct a proper opening to oe made, and tepid water then to be thrown into the chest, with the view of loosening and dissolving the coa- gula and washing them out Of the wound. The French writers, even the modern ones, ( Sabatier ) most absurdly recommend the injection of various detergent vulnerary de- coctions, and of solutions of honey of roses, soap, salt, fcc. What idea these authors can entertain of the great tendency to inflam mation of the lungs and pleura, or what good they can expect from such applica- tions, is difficult of conception. 1 am firmly convinced, that the meanest scribbler on surgery, in this country, would be ashamed of offering such advice. 5. When the wound is narrow, and situ- ated at the upper part of the chest, the ex- travasated blood cannot be discharged, un- less a counter-opening be made at the lower part of this cavity. The best place for mak- ing the opening, and the proper manner of executing the operation, are described under the head of Paracentesis. As soon as the opening has been made, the blood flows out. Its discharge is then to be promoted by such a posture as will render the open - ing depending. The old surgeons, who had much more fear than the moderns of letting the opening heal up, sometimes employed tents for the purpose of preventing this event, until all danger of another collection of blood or matter seemed to be over. However, as in these cases tents are apt to bring on in- flammation of the pleura and lungs, hinder the escape of whatever fluid is contained in the chest, and cause great irritation, pain, and even exfoliations from (be ribs, their use is now relinquished. As large tents had the effect of hindering the discharge of blood, or matter from the cavity of the chest, some of the old French surgeons employed a kind of wick ; but, in the present state of surgery, I do not con- sider that it would be at all edifying to enter into a comparison of these contrivances. If any means be ever requisite for keeping the opening from closing, there cannot be a better thing for the purpose than a short cannula, with a rim to keep it from slipping into the thorax, and two little rings for con’- fining it in its situation with a riband. This should only just enter deeply enough to have its inner orifice on a level, or a very- little further inward than the pleura costa- lis, so that it may not irritate the lungs. When the patient has been dressed, he is to be kept in bed, with his head and chest somewhat elevated, and his thighs bent, in which position the breathing will be least oppressed. It is usual also to recommend him to lie, as much as possible, on the siffe WOUNDS. Bu4 on which the operation has been done. He is to keep himself in as quiet a condition as he can. He is to be put on very low diet, and., if his strength allows, he is to be bled from the arm ; and this evacuation must be repeated, with other antiphlogistic means, as often as the urgency of the fever and in- flammatory symptoms indicates, and the strength allows. Bleeding from the arm, besides counter-acting inflammation in the chest, which is a principal source of danger, does good by lessening the force of the cir- culation in the wounded vessels, and thus diminishing the tendency to internal hemor- rhage. The old practice of keeping open wounds of the chest is now nearly exploded ; but, if it ever be adviseable, particular caution must be used not to let the tents, and pieces of the dressings, glide into the cavity of the pleura. Tulpius speaks of a Danish gentle- man who had been under a careless sur- geon, on account of a wound in the thorax, and who coughed up, six months afterward, a large tent. A similar fact is recorded by Hildanus. A man was stabbed in the right side of the chest, near the axilla, between the second and third ribs. Fora fortnight, a great deal of blood was discharged both from the wound and the mouth. The wound healed ; but the patient continued to be afflicted with considerable difficulty of breathing, an incessant cough, and to spit up a greenish, fetid matter. Three months afterward he coughed up two tents, which had slipped into the cavity of the thorax. A relaxation of the antiphlogistic regimen must be made with very great circumspec- tion. Too much nourishment, talking too frequently, and any exertion, are circum- stances which may induce a renewal of the hemorrhage, and extravasation. Vesa- lius saw an accident of this nature happen a fortnight after the wound, and eleven days after the operation for empyema. A soldier, who had been stabbed in two places with a sword above the right nipple, was attacked with fever, difficulty of breathing, restlessness, and acute pain at the bottom of the chest. These symptoms induced Vesa- lius to infer, that an extravasation had taken place ; but he was afraid of making an open- ing in the chest for fear the hemorrhage should still continue from the wounded vessels. However, as the patient remained in the same state the fourth day after the receipt of the wounds, and he still had strength enough, Vesalius undertook the operation, by which a considerable quan- tity of extravasated blood was discharged. The patient felt great relief at the instant. The oozing of blood continued for a few days, after which a favourable suppuration took place in all the three wounds, and the case was expected to end well. But the patient having regained his strength, and taken too much food, the recurrence of he- morrhage caused his death. Lombard saw' a soldier die instantaneously of internal hemorrhage, brought on by throwing a bowl at some nine pins, two months after he had been cured of a wound of the lungs . When the edges of a penetrating wound of the chest are to be brought together, writers state, that the patient should be re- quested to make a strong inspiration, with the wound closed, and then a long, slow expiration with it open, and so on, till as much of the air is discharged from the tho- rax as possible, and then the wound is to be accurately closed w ith sticking-plaster. From what has been observed, however, in the article Emphysema , it will appear, that when there is a direct opening into the thorax, so as to admit the external air, the lungs on one side coilapse, and remain so till the wound is healed, and the air absorb- ed. When one of these organs is wounded, a collapsed state is indeed the best condi- tion in which it can possibly be for a cer- tain time, that is, till the breach of conti- nuity in it is healed. Schemes for making the lung expand, by exhausting the air from the cavity of the pleura, may be amusing on paper, but, 1 apprehend, they will never be of real use in practice. Fistulse sometimes continue a long while after w ounds of the thorax. Platner men- tions an instance in which there was a fistu- lous opening, out of which the air rushed with sufficient force to blow out a candle. The patient lived a long while in this state without suffering any particular inconve- nience. Another occasional consequence of a wound of the chest, is a hernia of the lungs,, an affection of which Sabatier met with an example. A soldier, thirty years of age, W'as wounded with a bayonet in the right side of the chest, between the middle part of the fifth and sixth true ribs. The wound healed ; but, as the intercostal muscles had been divided to a great extent, and could not be approximated with precision, an empty space was left under the integuments, which a!low r ed a piece of the lungs, as large as a walnut, to protrude between the ribs. The swelling enlarged at the time of inspi- ration, and grew smaller when expiration took place, occasioning merely a slight pain without any oppression in the chest. Though so much has been written on the subject of discharging blood from the chest, in cases of extravasation within that cavity, the operation is very rare. During the last twenty-four years, I have never heard of its being done by any of the surgeons in Lon- don. In military surgery, however, the practice is occasionally exemplified. (Lar- rey, M6m. dc Chir. Mil. T. 2, p. 158, 8pc.) No doubt, the true reason of the operation being uncommon, is the obscurity in the diagnosis, the symptoms being all of an equivocal nature Even Larrey, generally so partial to operations, recommends the immediate closure of all wounds of the chest, excepting such as are complicated with injury of the intercostal artery, be- cause, (says he) unless very considerable vessels of the lungs are injured, (in which case nothing cam bo of any use) either no WOUNDS C(*j extravasation, or only a trivial one, happens, which, under the employment of rigorous ♦antiphlogistic treatment, may be dispersed by absorption. (P. 127.) In the general propriety of closing all wounds of the chest, I entirely concur with Larrey, Pelletan^ t Boyer, and Dr. Hennen. ( On Military L Surgery, ed. 2, p. 373.) Consult Sabatier, De la MMecine Opera- toire, T. 2. Joum. de Med. Militaire, 7 Tomes. Schmucker, Wahrnehmungen, 2 B. Berlin, 1774 — 89. J. Bell , on the JVa'ure I and Cure of Wounds, Ed. 3. D. J Larrey, Mdm. de Chir. Militaire, 8 vo. Paris, 1812 — 1817, in various places. John Hennen, Principles of Military Surgery, Ed. 2, 8 vo. Edinb. 1820. Wm. Maiden, an Account of a Case of Recovery, after an extraordinary Accident, 4/o. Lond. 1812. The injury here referred to is one of the most extraordinary on record ; the shaft of a gig having been driven with the greatest violence between the sternum and lungs. Sir A. Halliday, in Edinb. Med. and Surg. Joum. Vol, 1 1, p. 140 ; a Recovery from a Gunshot Injury, in which a great part of the Shoulder was carried away , and the Lungs and Pericardium were exposed : to the authenticity of this Case / can bear wit- ness myself, having been at the Field Hospital, when the Soldier arrived from the Trenches, near Antwerp. Wounds of the Abdomen. — Here one of the chief causes of danger is the tendency of the peritoneum to inflame. Every pene- trating wound of the belly is apt to excite this inflammation, which too often extends itself over all the viscera, and terminates in the death of the patient. There are (says Mr. John Bell) a thousand occasions, on which the delicacy of the peritoneum may be observed. The wound of the small sword, and the stab of the sti- letto, explain to us, how quickly the perito- neum, and all its contained bowels, inflame from the most minute wound, although the injury be almost too small to be visible on the outside, and scarcely within ; for often, upon dissection, no intestines are discover- ed wounded, and no feces have escaped into the abdomen. In subjects who die after lithotomy, we find the cavity of the perito- neum universally inflamed. The operation of the Caesarean section is fatal, not from any loss of blood, for there is little bleed- ing; nor from the parts being exposed to the air, for patients also die in whom the womb bursts, and where the air has no pos- sible opportunity of insinuating itself ; but the case proves fatal from the inflamma- tion which is always disposed to originate from wounds of the peritoneum, small as I well as great. ( Discourses on the Nature and ♦ Cure of Wounds, p. 310, edit. 3.) But although there can be no doubt that the wound, abstractedly considered, is the most frequent occasion of this dreaded in- flammation ; yet it sometimes happens that the inflammatory consequences must be ascribed to another kind of cause. If an intestine be wounded, its contents may, under certain circumstances, be effused in Voi.. IT. 84 the abdomen ; it the fiver, spleen, kidney, or any large vessel be injured, blood may be poured out among the viscera ; if the gall-bladder be wounded, bile may be effu- sed ; and if the bladder be pierced, the urine may escape into the abdomen. Now all these fluids are extraneous substances with respect to the surfaces, with which they often come into contact, and, as such, they give rise to inflammation of the peri- toneum and viscera. Wounds of the belly are divided, by almost all writers, into such as penetrate the cavity of the abdomen, and into others, which only interest the skin and muscles. The former differ very much in their na- ture, and degree of danger, according as they do, or do not, injure parts of impor- tance, contained in the peritoneum. The latter are not remarkably different from the generality of other superficial wounds. The chief indications are to lower inflam- mation, and to prevent collections of mat- ter. A few particularities, however, in the treatment of superficial wounds of the ab- domen, merit attention. Superficial Wounds . — The most ancient surgeons, and their successors, down to the present day, have recorded, that wounds of tendinous parts frequently give rise to very unpleasant consequences. Almost the whole front of the abdomen is covered with tendinous expansions, and, on this account, -it is not unusual to see punctured wounds in this situation followed by extensive in- flammation, and the formation of abscesses. At the same time, the patient is affected with a great deal of inflammatory fever. He suffers aedte pain, sickness, hiccough, and considerable disturbance of the ner- vous system. ( Callisen , Syst. Chirurg. Ho- diernce , Vol. 1 ,p. 698, Hafniee, 1798.) When the tension and swelling of the abdomen abate, shiverings sometimes occur, and in- dicate the occurrence of suppuration. The matter sometimes accumulates in the tendi- nous sheath of the rectus muscle, and, when the collection in this situation remains un- discovered until a pointing appears, no sooner does the abscess burst, or it is open- ed, than an extraordinary quant ity of matter is discharged. The surgeon ^should care- fully remember the nature of this kind of case, as there is frequently not sufficient alteration in the appearance of the integu- ments to denote either the existence or the extent of the suppuration. Such an abscess forms one remarkable exception to the excellent general rule of allowing acute phlegmonous abscesses to burst of their own accord. In the present instance, there is an aponeurotic expansion, intervening between the abscess and the skin, and nothing retards the natural pro- gress of the matter to the surface of the body so powerfully as the interposition of a tendinous fascia. But, even in this circum- stance, the propensity of pus to make its way outward is often seen to have immense influence. Though there is only a thin membrane (viz. the peritoneum^ between 666 WOUNDS. matter so situated* and the cavity of the abdomen, the abscess after a time mostly points externally. Tiie proper treatment of this case is to prevent the surprising accumulation of mat- ter, and rapid increase of mischief, by making a depending opening, sometimes at the very lowest part of the sheath of the rectus muscle, and this, as soon as the lodge- ment of matter is clearly ascertained. If ever there be a case in which it is ad- vantageous and justifiable to make an early, dilatation of a punctured wound, in order to prevent the above-described ill conse- quences, it is unquestionably the present one. Such practice, indeed, is particularly recommended by Callisen, in addition to the strictest antiphlogistic means. (See Syst. Cliir. Hodiernce, Vvl.1,p. 698, edit. 1798.) Sometimes the matter is formed between the external and internal oblique muscles, and spreads to a great extent. The pus may even insinuate itself into the abdomen, and the case end fatally. Such an example is recorded by Dr. Crowther, of Wakefield. In this instance, however, the disease pro- ceeded from a contusion, not a wound. (See Edinb. Med. and Surgical Journal t Vol. 2 ,p. 129.) Superficial wounds of the abdomen are to be treated on the same principles as simi- lar wounds in other situations. The indica- tions are to prevent inflammation as much as possible, and, if suppuration should be inevitable, to let out the matter by a de- pending opening as soon as the abscess is known to exist. The inflammation is to be checked by general and topical bleeding, low diet, emollient clysters, diluent beve- rages, quietude, opening medicines, cold applications, or fomentations and poultices, and the mildest and most simple dressings. (See Inflammation.) Whenever the abdominal muscles are wounded, they should be relaxed, and the patient kept quiet in bed. A very impor- tant point in the treatment of wounds of the parietes of the abdomen, is to afford a degree of support to the wounded parts, so that the pressure of the viscera may be re- sisted. The sides of the abdomen are almost wholly composed of soft parts, which easily yield. No part of the front, or sides of the abdomen, is supported by a bony structure, and as the viscera are for the most part, more or less moveable, and closely com- pressed by the abdominal muscles, and dia- phragm, they are liable to protrude, when- ever the resistance of the containing part3 is not sufficiently powerful. Hence all wounds of the abdomen, especially those, in which both the integuments and muscles have been cut, demand strict attention to the precau- tion of supporting the wounded part, and this, though the peritoneum itself should not happen to be divided. The patient ought to keep as much as possible in a horizontal position, and suitable compresses and bandages should be applied. And, in order to guard against hernia?, the parts should be supported, in this way, a consi- derable time after the wound is healed. ’I'he peritoneum being connected by means of cellular substance with the inner surface of the abdominal muscles, there is always some risk of the inflammation of these parts extending to that membrane. The danger must be averted by the rigorous em- ployment of antiphlogistic treatment. What renders the event still more dangerous, is, that when one point of the peritoneum is affected, the inflammation usually spreads with immense rapidity over its whole ex- tent, and too often proves fatal. As superficial wounds of the abdomen are to be treated on the general principles, ap- plicable to all resembling w r ounds in other situations, it is hardly necessary to state, that union by the first intention, if possible, is always to be attempted. Of Wounds penetrating the Cavity of the Abdomen — The first thing which the surgeon is generally anxious to know, when he is called to a wound of the belly is, whether the wound penetrates the cavity of the ab- domen, and whether any of the viscera are injured. When the wound is extensive, and the bowels protrude, the first part of the ques- tion is at once decided. But when the wound is narrow, and the viscera do not protrude, it is more difficult to know, whe- ther the cavity of the abdomen is penetra- ted or not. An opinion, however, may be formed, by carefully examining the wound with a linger or a probe ; by observing, if possible, how ranch of the weapon is stain- ed with blood -, considering the direction in which it was pushed ; the quantity of blood lost, the state of the pulse, and whether any bile, feces, or other fluids, known to be na- turally contained in some of the abdominal viscera, have been discharged from the ori- fice of the injury. When the wound is sufficiently large to admit the finger, a surgeon can always learn, whether the injury extends into the abdo- men, because the smooth lining of that cavity, and the contained bowels, may be easily felt. There is one chance of decep- tion, however, arising from the possibility of mistaking the inside of the sheath of the rectus muscle for the cavity of the perito- neum ; and when the examination is made with a probe, particular caution should be used in forming a judgment of the nature of the case ; for the parts are so soft and yield- ing, that a very little force will make the instrument pass a considerable way inward. Every examination of this kind should always be undertaken, if possible, when the patient is exactly in the same position, iu which he was at the time of receiving the wound. Formerly, injections were some- times employed as tests of the penetration of the cavity of the abdomen. This absurd experiment is now very rightly exploded. It is well known to the moderns, that the space, termed the cavity of the abdomen, is, in fact, completely filled with the various viscera, and that in general, an injected WOUND; 067 fluid would not so easily find its way into the bog of the peritoneum, as an unreflect- ing person might suppose. And if it were propelled with much force, it would be quite us likely to insinuate itself into the cellular substance of the parietes of the abdomen, or perhaps, into the sheath of the rectus muscle. The least tortuosity of the wound, or a piece of bowel, or omentum, lyiug against the internal orifice of the injury, would also completely prevent an injection from passing into the abdomen. When a considerable quantity of blood issues from a wound of the abdomen, we may pronounce, almost with certainty, that some large vessel, within its cavity, is inju- red. Excepting the epigastric artery, which runs on the forepart of the abdomen, along the inner surface of the rectus muscle, no large vessel is distributed to the muscles and integuments. At the same time, it is deserving of particular notice, that a large artery may be opened in the abdomen, and not a drop of blood be discharged from the wound. In such cases, the consequent symptoms quickly lead to a suspicion of what has hap- pened. The patient complains of extreme debility and faintness ; his pulse falters ; he has cold sweats; and if the bleeding should not speedily cease, these symptoms are soon followed by death. Sometimes, the extension of the wound into the cavity of the abdomen, is from the first quite manifest, being indicated by the escape of chyle, bilious matter, feces, or other fluids. The vomiting up of a consi- derable quantity of blood, or its discharge by stool, affords also the same information. The urine however, may flow from a wound, which does not actually penetrate the abdo- men, for the kidneys, ureter, and bladder may be said to be out of the abdomen, be- cause they are really on the outside of the cavity of the peritoneum. When none of the above symptoms occur : when neither the finger nor probe can be introduced ; when none of the fluids, known to be contained in the various receptacles in the abdomen, are discharged from the wound; when the pulse remains natural, and the pain is not excessive ; there is rea- son to hope, that the wound has not injured parts of greater consequence, than the in- teguments and muscles. (Encyclopedic Mtthodique, Partie Chir. Art. Abdomen.) I have now taken a survey of the criteria, commonly noticed by writers, for the pur- pose of enabling surgeons to discriminate a wound, which penetrates the abdomen, from one which is more superficial. My next duty is to warn the practitioner, that too much solicitude to determine this point, is very frequently productive of serious harm. It may be set down, as an axiom in surgery, that in general , whenever the probing of a wound is not rendered absolutely neces- sary by some particular object in view, it may be judiciously omitted. A narrow, oblique wound may enter the cavity of the abdo- men, without there being any particular method of ascertaining, whether it has done so, or not. However, this want of positive information is of no practical importance; for, when there are no urgent symptoms, evincing the nature of the case, the treat- ment ought obviously to resemble that of a simple wound ; and whether the wound be deep, or superficial, antiphlogistic remedies are indicated. The edges of a wound, penetrating the abdomen, but unattended with injury of the viscera, arc to be brought together with sticking-plaster, in the same way as commoa wounds. Sutures are not generally neces- sary. Numerous cases may be found in the records of surgery, proving that wounds of the abdomen may be easily united without sutures, provided the surgeon take care to avail himself of the assistance, which may be derived from a suitable position and a proper bandage. But such cases are less decisive, than relations of the Ca?sarean operation, the extensive wound of which admits of being healed by the same simple means. It is not my intention to assert, that in the majority of these examples, sutures were altogether dispensed with; but, the ligatures frequently cut their way through the skin and muscles, and the ap- plication of others was impossible, either on account of the particular state of the case, or the patient’s aversion to them. Still the union of such wounds was accomplish- ed. A bandage, made on the same plan, as that with eighteen tails, would be extremely convenient for longitudinal wounds of the abdomen. (See Pibrac in Mtm. de VAcad. de Chir. T. 3, 4/o.) In the treatment of wounds of the abdo- men, sutures may generally be relinquished, not only without harm, but with benefit; for their employment is sometimes the cause of bad symptoms. In one instance, the hic- cough and vomitihg could not be appeased by any remedy which was tried. On the fourth day, the wound was inflamed and painful, and it was judged proper to cut away two sutures, and employ only simple dressings, with the view of diminishing the pain and swelling. The symptoms quickly abated, and in a week, were entirely cured, the wound healing up very well. (Op. cit.) However, there are circumstances, in which it would be impossible to dispense with sutures. If, for instance, the belly were torn open from one side to the other with a bullock’s horn ; or if it were exten- sively divided with the tusks of a wild boar, a stag’s horn, a razor, &c. and the inflated intestine could not be kept from protru- ding ; some stitches would be absolutely necessary, but even then, they should be as few as possible. (Sabatier, Mtdecine Optra- toire, T.l, p. 214, edit. 2.) “ Oufgood old surgeon Wiseman (observes Mr. John Bell) has said with great simplici- ty, as a great many have said after him, it frequently happenetb, that a sword passetli through the body, without wounding any considerable part.’ He means, that a rapier, or ball, often passes quite across the belly, WOUNDS. 60S in at the navel, anti out at the back, and that without one bad sign, the patient recovers, and as has very often happened, walks abroad in good health, in eight days; which speedy cure has been supposed to imply a simple wound, in which all the bowels have escaped. But we see now, how this is to be explained ; for we know, that in a thrust across the abdomen, six turns of intestine may be wounded, — each wound may ad- here ; adhesion, we know, is begun in a few hours, and is perfected in a few days ; and when it is perfect, all danger of inflam- mation is over; and when the danger of in- flammation is over, the patient may walk abroad ; so that we may do, just as old Wiseman did in the case here alluded to, ( P . 98, the case of a man, who was wound- ed across the belly, and well and abroad in seven days,) ‘ Bleed him, and advise him to keep his bed and be quiet.’ In short, a man, thus wounded, if he be kept low, has his chance of escaping by an adhesion of the internal wounds.” ( Discourses on the Nature and Cure of Wounds , p. 329, 330, edit. 3.) The truth of these observations is well illustrated in a case mentioned by Dr. Hen* nen, in which a soldier recovered, whose abdomen u T as pierced with a ramrod, which stuck so fast in the vertebrae, that some force 'was required to disengage it. ( On Military Surgery , p. 402, ed. 2.) When a man is stabbed or shot in the belly, and none of the bowels protrude, the wisest plan is to keep the patient as quiet as possible, have recourse to copious and repeated bleed- ing, prescribe anodynes, and the lowest fluid diet, and apply light superficial unirritating dressings. In the event of severe pain and swelling of the belly coming on, leeches, fomentations, the warm bath, and emollient poultices, will be necessary, and nothing will now avail, except the most rigorous employment of antiphlogistic remedies. As Dr. Hennen observes, the best means of emptying the bowels are oleaginous clysters, and if any internal medicine be given, as a purgative, it should be of the mildest nature. (On Military Surgery, p. 402, ed. 2.) Castor oil is perhaps the best; but, on the whole, for some few days, I would hardly venture beyond the use of clysters for procuring evacuations from the bowels. Suppuraiionin the Abdomen, in consequence of Wounds. — Abscesses within the bag of the peritoneum are far from being common. As a late writer well observes, "the con- taining and contained parts of the abdomen present to each other an uniform and con- tinuous surface of membrane. This mem- brane is of the serous class, and the species of inflammation, to wdiich it is especially subject, is that, which has been denominated the adhesive. The membrane, lining the intestinal canal, is of the mucous elffs, and the ulcerative inflammation is the species, to which this class is liable. This benefi- cent provision is an irresistible evidence of the operation of a salutary principle in dis- ease. If the inflamed peritonfeurn had run directly into suppuration : ulceration of the surrounding parts would have been required for an outlet ; and if the inlernal surface of the irritated bowel had tended to form ad- hesions, the canal would have been in con- stant danger of obliteration.” (Travers on Injuries of the Intestines, Ipc. p. 10.) That collections of matter, however, do sometimes take place in the cavity of the abdomen, in consequence of wounds, is a fact, of which there are too many proofs on record for the possibility of the case to be doubted. At this moment, be it sufficient to refer to two examples of the occurrence, as related by Mr. B. Bell. (System of Surgery , Vol. 5, p. 256.) If the abscess were in any other part of the body, and did not readily point, the wisest practice would undoubtedly be to make an opening sufficient for the evacua- tion of the matter. But suppuration in the abdomen can seldom be known with cer- tainty in an early stage of the case : for the abscess is so deep, that no fluctuation, nor swelling, is perceptible, until the quantity of pus is considerable. Nor would it be judicious to expose the patient to the hazard, which might arise from making an opening into the abdomen, merely for the sake of discharging a small quantity of matter. Many writers impute much of the danger of wounds of the abdomen to the entrance of air into the cavity of the peritoneum, in inculcating such opinions, however, they betray an inaccuracy of observation, which a very little reflection would have set right. Too much stress has long been laid on the introduction of air into the abdomen, as being a cause of inflammation. The fact is, the cavity of the belly is always so com- pletely occupied by the several viscera, that the whole inner surface of the peritoneum is invariably in close contact with them, and therefore, air cannot easily diffuse itself from the wound, throughout the abdomen After tapping, in dropsical cases, inflamma- tion seldom arises, though here the air has quite as good an opportunity of entering the abdomen, as in any case of wound. The peritoneum in animals has been infla- ted, without any inflammation being exci- ted. In cases of tympanitis, the peritoneum is distended with air, and yet both this membrane and the bowels are quite unin- flamed. In the human subject, it seems probable, that if a wound were made in a vacuum, the breach of continuity itself would be an adequate cause of inflamma- tion. It may also be remarked, that collec- tions of matter in the abdomen are almost always completely circumscribed, and sepa- rated from the general cavity of the perito- neum, by the adhesion of the viscera to each other, and to the inside of the'peritoneum. 1 am of opinion, that no surgical writer has succeeded so well, as Mr. John Bell, in exposing the absurd apprehensions, not un - commonly entertained by practitioners, re- specting the entrance of air into the abdo- men and oilier cavities of the body. Ho inquires, 1st. Whether air can really get into the cavity of the abdomen ? and, 2dly. WOUNDS. 069 "Whether, it it were there, it would produce bowels are exposed to the air. ' ( Discourses the dreadful effects ascribed to it ? on the Nature of Wounds , p. 343, 344.) Upon the first question, his arguments run In adverting to the question, whether ait’ thus: — “ Suppose a wound of an inch in is so irritating to the cavities of the body as length : — suppose the bowel to have sunk, many have supposed, Mr. John Bell critici- in some strange way, into the pelvis, for ses with much spirit and success, the opi- example, so as to have left a mere vacuum ; nions, published on this subject by Mr. A. what should happen with the flexible pa- Monro, in his account of the Bursae Muco- rietes of the abdomen ? Should they stand sa?, as the annexed quotations will show, rigid, while the air rushed into the cavity “ That the vulgar should believe, the first to fill it ? No, surely. But, on the contrary, superficial impression that strikes them, of the walls of the abdomen would fall toge- ther, and the pressure of the outward air, far from making the air rush in by the outward wound, would, at once, lay the belly flat, and close the wound. But, since the walls of the abdomen are not flaccid, nor the ca- vity empty, but the abdomen full, and the flat muscles, which cover it, acting strongly, the effect must be much more particular ; for, the moment that the belly is wounded, the action of the muscles w'ould force out part of the bowels ; the continuance of that action is necessary to respiration : the re- spiration continues as regular after the wound as before ; and the continual pres- sure of the abdominal muscles, and the diaphragm, against all the viscera of the ab- domen, prevents the access of air so effec- tually, that though we should hold such a wound open with our fingers, no air could pass into the abdomen, further than to that piece of gut which is first touched with the finger, when we thrust it into the abdomen. Nothing is absolutely exposed to the air, ex- cept that piece of intestine which is without the abdomen, or that, which we see, when we expose a small piece of the bowels, by holding aside the lips of the wound. The pressing forward of that piece, and the pro- trusion of a portion of the gut, proportioned always to the size of the wound ; the pres- sure from behind keeping that piece pro- truded, so that it is with difficulty we can push it back with our finger; this incessant pressure, in all directions, is an absolute se- curity against the access of air. The intes- tine comes out, not like water out of a bottle, the place of which must be supplied by air entering into the bottle, in proportion as the water comes out ; but, the gut is pushed down by the action of the muscular walls of the abdomen, and that action follows the intestine, and keeps it down, and prevents all access of the air, whether the gut con- tinue thus protruding, or w hether it be re- duced ; for, if it be reduced, the walls of the abdomen yield, allowing it to be thrust back, but admitting no air. Those, who want to know the effect of air, diffused within the cavity of the abdomen, must make other experiments, than merely cutting open pigs’ bellies ; — they must give us a fair case, without this unnecessary wound. We will not allow them to say, when they cut open the belly of any creature, with a long inci- sion, that the inflammation arises from the air; much less shall we allow them to say, when they open the belly with a smaller incision, that, by that little incision, the air gets into the abdomen, and that all the air hurting a wound or sore, is by no means surprising ; but it is not natural that men, bred to philosophy, should allow so strange an assertion as this, without some kind of proof. ThM the air which we breaihe, and which we feel upon the surface so bland and delightful, should have so opposite a relation to the internal parts, that it should there be a stimulus, more acrid and more dangerous than the urine, is- not to be believed upon slight grounds. I do affirm (says Mr. John Bell) that it remains to be proved, that this fluid, which seems so bland and pleasant to all our senses, and to the outward surface, is yet a horrible stimulus when admitted, as a celebrated author grandly expresses it, ‘ into the deep recesses of our body.’ ( Monro's Bursae Mucosae.) With how much reason Mr. John Bell objects, that this, doctrine is unfounded, will be manifest to every man of any discern- ment, or impartiality. “ The air, for instance, escapes from the lungs, in a fractured rib, and first goes abroad into the thorax ; then into the cellular sub- stance ; then the emphysematous tumour appears; but often without any scarifica- tions, with very little care and assistance on our part, the air is absorbed, the tumour disappears, and, without inflammation of the chest or any particular danger, the man gets well. Here then is the air, within the cavity of a shut sac, filling the thorax, and oppressing the lungs, without any danger- ous inflammation ensuing. | u That the air may be pushed under the cellular substance all over the body, without causing inflammation, is very plain, from the more desperate cases of emphysema, where the patients, after living eight or ten days, have died, not from inflammation, but from oppression merely, the body being so cram- med with air, that even the eyeballs have, upon dissection, been found as tense as blown bladders. We have also many ludi- crous cases of this kind, which prove this to our perfect satisfaction. Soldiers and sailors sometimes touch the scrotum with a lancet, introduce a blowpipe, and blow it up to an enormous size, imitating her- nia?, by which they hope to escape from the service. The old story of a man, who was so wicked as to make a hole in his child’s head, and blow it up, that he might show the child in the streets of Paris for a mon- ster, is well authenticated ; and I have lit- tle doubt, that a fellow who knew how to do this, w'ould blow it up every morning, and squeeze it out when he put the child to bed at night. Some villanous butchers, hav* WOUNDS. oru ing a grudge at a soldier, found him lying drunk under a hedge ; they made a little hole in his neck, and blew it up, till he was like a bladder, or, as Dr Hunter describes the disease of emphysema, like a stuffed skin." (P. 3S8, 389.). After many other pertinent observations, blended with appropriate satire on the ex- travagant notions professed by Monro, on the bad effects of the air in lithotomy, operations for hernia and hydrocele, the Caesarian section, Lc. Mr. John Bell most justly holds up to ridicule the propositions of Dr. Aitk to perform this last operation wider the cover of a warm bath , in order to exclude the air. “ This, though It may seem to be a scurvy piece of wit, was really pro- posed in sober serious earnest. But (adds Mr. John Beil) the admission of atmospheric air, as a stimulus, when compared with the great incisions of lithotomy, of hernia, of hy- drocele, of Caesarean section, of the trepan, is no more than the drop of the bucket to the waters of the ocean. And it is just as p.oor logic to say, that after such desperate operations, these cavities are inflamed by the admission of air, as it would be to say, (as Monro did) that when a man is run through the pericardium with a red-hot po- ker, that the heart and pericardium are in- flamed by the admission of the air.” (P. 847, Edit. 3.) Enough, I conceive, has been said, to dis- pel all the idle fear and prejudices, which have prevailed concerning the bad effects of the air in wounds of the abdomen, as well as several other cases. When so justly emi- nent a man as Dr. Alexander Monro, senior, \vas disturbed by such apprehensions, it is not wonderful that many a poor ordinary member of the profession should have been terrified nearly oui of his wits upon the sub- ject; and for quieting this alarm, and expo- sing its absurdities, I really think Mr. John Bell deserving particular praise. In general, 14 all cases of wounds of the abdomen, it is an excellent rule never to be officious about abscesses which may take place, nor to exhibit a partiality to such ex- periments as have been devised for learning precisely what bowel is wounded. It is quite time enough to interfere, when the urgency of the symptoms confirm any sus- picions which may be entertained. A great deal of harm is frequently done by hand- ling and disturbing the wounded parts more than is necessary, and it is well known that wounds, at first attended with alarming symptoms, frequently have a favourable ter- mination. Swords, balls, and other wea- pons, sometimes pass completely through the body, without the patient suffering after- ward any threatening symptom, or, indeed, any effects which, abstractedly considered, would authorize the inference, that the vis- cera had been at all injured. Severe inflam- mations may not end in suppuration, and when pus is formed, it is sometimes absorb- ed again. Nothing then indicates the ne- cessity for the discharge of purulent matter n. the abdomen , unless the fluctuation and situation of the abscess be very distinct, and the quantity and pressure of the matter clearly productive of inconveniences. Un- der these circumstances, the surgeon should make a cautious puncture with a lancet. Protrusion of the Viscera. — The omentum and small intestines are the parts most liable to protrusion ; but, in large wounds, the great intestines, the stomach, and even the liver and spleen, may project through the opening. The general symptoms, indicating a protrusion of the parts, are sufficiently ob- vious ; but, it deserves attention, that, in fat subjects, the adipose membrane may project from the wound, and put on somewhat of the appearance of omentum. The special symptoms are to be collected from a know- ledge of the natural situation of the parts, and reflecting what region of the abdomen is wounded. ( Callisen , Syst. Chir. Hodiemce , T. 1 ,p. 702 and 703, edit. 1798.) From penetrating wounds considerable porjjons of the bowels, or omentum, some- times protrude, and though these viscera may not have received injury, yet their being displaced, is sometimes productive of fatal consequences. The best mode of preventing such mis- chief, is to return the viscera into the cavity of the abdomen as speedily as possible. Almost all authors recommend fomenting the displaced parts, previously to the attempt at reduction ; but in giving this advice, they seem to forget, that while time is lost in this preparatory measure, the protruded bowels suffer much more harm from exposure, that is to say, from the very circumstance of their being out of their natural situation, than they can possibly receive good from any application made to them. No kind of fomentation can be half so beneficial, as the natural warmth and moisture of the cavity of the abdomen. In order to facilitate the return of a protruded piece of intestine, or omentum, the abdominal muscles should be relaxed by placing the patient in a suitable posture, and the large intestines emptied with a glyster. In mentioning the last measure, it is not meant, that the surgeon should delay the attempt to reduce the part, until the glyster has operated. No, this means is only enumerated as one that may become serviceable, in case the surgeon can- not immediately accomplish the object in view. — The mesentery Ought always to be reduced before the intestine ; the intestine before the omentum ; but, the last protruded portion of each of these parts ought to be the first reduced. It is only w T hen the intestine and omen- tum are free from gangrene and mortifica- tion, that they are invariably to be returned into the cavity of the belly, without hesita- tion. Also, when the protruded parts are covered with sand, dust, or other extraneous matter, they should be tenderly washed with a little tepid water. For the reduction of the parts, the fore- fingers are the most convenient, and it is a rule to keep the portion first returned, from protruding again, by one finger, until it has WOUNDS. i been followed by another portion, introdu- ced by the other finger. The second piece is to be kept up, in the same way, by the finger used to return it; and so on, till the displaced parts have all been put into their natural situation. In attempting to reduce a piece of pro- truded intestine, the patient should be placed in the most favourable posture : the head and chest should be elevated, and the pelvis raised with pillows. Nothing can be more absurd, than the advice to put the thorax rather lower than the pelvis, in order that the weight of the viscera may tend to draw inward the protruded parts. This is another erroneous idea, arising from the ridiculous supposition, that a great part of the abdomen is actually an empty cavity. The relaxation of the abdominal muscles is a much more rational and useful object. When this is properly attended to, and the above directions observed, and the wound is not exceedingly small, in relation to the bulk of the protruded viscera, the parts may generally be reduced. But in addition to what has been already stated, it is neces> sary to remark, that the pressure should be made in a straight direction into the abdo- men ; for when made obliquely, towards the edges of the wound, the parts are liable to suffer contusion, without being reduced, and even to glide between the layers of the abdominal muscles, and become strangula- ted. When the wound is in the front of the abdomen, pressure made in this unskilful way may force the viscera into the sheath of the rectus muscle, and cause the same perilous symptoms as arise from an incarce- rated hernia. (See Hernia.) When the reduction seems complete, the surgeon should assure himself of it, by in- troducing his finger into the cavity of (he abdomen so as to feel that the parts are all actually reduced, and sutler no constriction between the edges of the wound and the viscera in the abdomen. A difficulty of reduction may arise from the protruded intestines being distended with feces or air. In this circumstance, the contents of the gut may frequently be made to pass by degrees into that portion of the intestinal canal, which is within the abdomen. In order to accomplish this pur- pose, the surgeon must press the contents of the bowel toward the wound ; and, if be succeeds in emptying the part, he will com- monly experience equal success in his next attempt to replace it in the abdomen. Sometimes, in cases of narrow stabs, considerable pieces of intestine protrude, and cannot be reduced without doing im- prudent violence to the bowel. Under these circumstances, the dilatation of the wound is indispensable. However, when the reduction seems almost a matter of im- possibility, on account of the smallness of the wound, if the surgeon be careful to re- lax the abdominal muscles, draw a little more intestine out of the wound, and gently press the contents of the bowel through the constriction into the abdomen, he will fre- quently succeed in reducing the parts, with- out using the knife. Whfen such operation is unavoidable, the dilatation should be made in a direction which will not endanger the epigastric ar- tery, and, if possible, in the same line as the muscular fibres. We are also advised to make the incisiou upward rather than downward, when it can be done with equal convenience, be- cause it is supposed the first direction will be followed by less danger of hernia. ( Sa- batier , Medecine Opiratoire, T. 1, p. 220, Ed. 2. Callisen , Syst. Chir. Hod. T. 1, p. 705.) If, however, the upper angle of the wound correspond to the direction of the suspensory ligament of the liver, writers advise making the dilatation at the lower angle, in order to incur no risk of hemor- rhage from the umbilical vein. In the. adult, this vessel is generally obliterated, and turned into a ligamentous substance ; though it would appear that, in a few in- stances, it remains pervious to the navel, Hildanus saw a young man die instantly in consequence of a stab in the belly between the false ribs and the umbilicus ; and, on opening the body, he found blood effused from a wound of the umbilical vein. It has been feared, also, that cutting the suspen- sory ligament of the liver might give rise to such a displacement of that viscus as would interrupt the freedom of respiration, or obstruct the circulation of the blood in the vena cava. But the apprehension is un- founded ; for Riolan found this ligament ruptured and retracted towards the liver in a nimble Ethiopian female dancer, whose respiration had not suffered any particular disturbance during her lifetime. ( Sabatier , Mid. Opiratoire, T.l,p. 220, 221, Ed. 2.) The incision should never be larger than absolutely requisite, as hernia is much dis- posed to occur wherever the peritoneum has been divided. The operation may be done with a curved bistoury and a director, much in the same way as is done in cases of strangulated ruptures. (See Hernia.) After the battle of Waterloo, many cases presented themselves in which the bowels and omentum protruded, and in several of these examples the reduction could not be effected before the wounds had been en- larged. So tightly also were the parts girt, that the operation was sometimes far from being easy. Instead of enlarging wounds of the abdo- men, it has been proposed to let out the air from the protruded intestines, by making small punctures with a needle, so as to lessen their volume sufficiently to make them reducible. The suggestion first origi- nated with Par6, who declares that he has practised the method with success. Rousset, his contemporary, also informs us that the plan was adopted by another surgeon in an instance where the epigastric region was wounded, and a large portion of the intes- tines protruded in a strangulated state. Pe- ter Eowe, an English surgeon, likewise assures us, that he frequently adopted the WOUNDS 672 practice, when other means failed. Garen- geot, Sharp, and Van Swieten, are all ad- vocates for Fare’s proposal ; but they recommend the employment of a round needle, which will merely separate the fibres of the intestinal canal, without cutting them, as a flat, triangular, sharp-edged needle would unavoidably do. These last writers, however, only sanction the practice when the quantity of protruded intestine is great, and the bowel is so enormously distended with air, that it would be impossible to re- duce the part, though the wound were en- larged, and every thing else put in practice, likely to bring about the reduction. Bui, as Sabatier remarks, the punctures must be entirely useless, if made with a fine needle, since they will be immediately stopped up with the mucous secretion, with which the inside of the bowels is constantly covered ; and if the punctures are made with a broad triangular needle, or a very large round one, as Desault and Chopart advise, they must be highly dangerous, inasmuch as they are likely to give rise to inflammation, and even to extravasation, within the abdomen. (Medecine Opiraloire, T. 1 , p. 10.) That small punctures in the bowel would not answer the purpose, but be obstructed by the villous or mucous coat, is a fact, which has been for a long time well known to surgeons. Callisen, among "others, has particularly noticed it: 11 Acu puncturae enim flatibus exitum parare nequeunt, siqui- dem tunica villosa foraminula obstruit,” &c. (Sys. Chir. Hod . T 2, p. 704.) It was the circumstance of small punc- tures being unavailing, that led Desault and Chopart to recommend the use of a large round needle : “ pour que louverture ne soit point bouchie par les mucositis dont les intes- tines sont enduils” But they were also aware of the danger of employing such an instrument, since they give us directions how to proceed in order to prevent extra- vasation and inflammation : On prd vien- dra V epanchement des matilres stercorales en passant, avant de reduire iintestin , line anse de fil dans la portion dc mesentere qui repond a la piqure pour la fixer contre les bords de la plait exttriture, et Von combuttra par Its remedes giniraux Vinfiammation que cet pi- qure peut attirer .” ( Traiti des Maladies Chirurg. T. 2, p. 135.) Richerand is still an advocate for puncturing the bowel, for which operation he boldly recommends a small hydrocele trocar. ( JVosogr . Chir. T. 3 ,p. 336, Ed. 4.) Mr. Travers, one of the latest and best writers upon this subject, most properly joins in the condemnation of the plan of pricking the protruded bowels. Blancard and others protested against this practice on the very sufficient ground of its ineffi- cacy. La Faye very truly says, it is a use- less as well as dangerous practice ; for the openings made by a round needle cannot give issue to the contained air.” Mr. Tra- vers then cites two cases, showing that even small stabs in a bowel will not prevent its becoming distended w ith air. “ A man was brought to St. Thomas'? hospital, on Saturday, the 30th of June last, (1811) who had been stabbed in the direc tion of the epigastric artery, oy the left side of the abdomen, by a case knife. He died in eighteen hours, apparently from the sud- den and copious hemorrhage, which had taken place within the belly, <\bout half a yard of ileon was protruded. The gut was highly discoloured, and so much distended, notwithstanding it was pierced in three places, that the wound of the integuments required to be freely dilated before it could be returned. The apertures were in fact obliterated by the mucous coat” “ It appeared upon the trial of Captain Sutherland (Ann. Reg. June 1809), for the murder of his cabin boy, that the intestines had been extensively protruded through a wound near the left groin, and had lain ex- posed for four or five hours ; that the dirk had pierced through one fold of intestine, and entered another ; that the w r ound of the intestine was half an inch long ; that the reduction could not be accomplished until the parietal wound was dilated ; and that the intestine was then returned, and the integuments sewed up.” (Travers on Injuries of the Intestines, p. 174, 176.) With respect to this last case, however, I must observe, that it does not satisfactorily prove what the author intends, namely, that the bowel was distended with air, though there was a wound in it half an inch long, for the evidence does not inform us that the difficulty of reduction was owing to this cause. I have seen a very small portion of omentum protrude through a wound, and baffle all endeavours to reduce it for nearly an hour. The first case adduced by Mr. Travers, however, is more explicit and in- teresting ; and we are to infer from it, and the observations of Haller, Callisen, &.c. that the punctures made in an intestine are not closed by mucus, as Sabatier and De- sault have asserted, but by the mucous coat itself. As the above expedient had been recom- mended by writers of some weight, I thought that the subject should not be passed over in silence, and without a caution to the reader, never to put any confidence in the method. The plan does not facilitate the business of the operator. There is not even this solitary reason in favour of the practice ; and though it may have answered when large needles were used, and some patients so treated may have recovered, every person, who has the least knowledge of the animal economy, will easily compre- hend how even the smallest opening, made in parts so irritable and prone to inflamma- tion as the bowels, must be attended with greater danger than would result from en- larging a wound of the skin and muscles. Besides, the air may frequently be pressed out of the intestine in a safer way, as I have already described. A wound of the abdomen, attended with one of the most considerable protrusions ot the viscera that 1 have ever read of, is re- wounds. horded by Mr. Hague, surgeon at Rippfcn : “ August 30th, 1808 (says this gentleman) I went to Norton Mills, about four miles from hence, to see John Brown, ret. 12 years, who had received a wound in the abdomen by a wool shears. OnHny arrival, which was little more than an hour after the accident, I found the poor lad in a very distressing situation ; the great arch of the stomach, and the whole of the intestinal ca- nal, (duodenum excepted,) contained with- in the abdomen, having protruded through the wound. The incision was on the left side of the body, commencing at about two inches below the scrobiculus cordis, and extending in a straight line near four inches in length, distant from the navel two inches, and he was uuite sensible, and had vomited so as to empty the stomach ; very little blood was lost. I immediately proceeded very carefully to examine the protruded viscera, none of which were wounded, and reduced them as quickly as possible, begin- ning with the stomach, and following the regular course of the intestines, in the latter portion of which 1 distinctly felt feces of father firm consistence. He complained of some pain during the reduction, though not much ; and expressed great relief when the parts were completely returned. I now desired an assistant to lay the palm of his hand over the wound, and make some pressure upon it ; for l found, that, without this, the parts would soon have protruded again by the action of respiration, which was oppressed and laborious. 1 brought the sides of the wound together by five su- tures, beginning from above downwards, and passed the needle on each side, quite through the integuments with the perito- neum, &Z.C. The wound was also dressed with adhesive plaster, and covered with a bandage.” (Vide Edinburgh Medical and Surgical Journal , Vol. 5, p. 129, <$/-c.) This case is interesting ; for notwith- standing so unlimited a protrusion of the viscera, and the circumstance of the parts being left unreduced for more than an hour, a recovery ensued, under the judicious em- ployment of bleeding, purging, anodynes, &c. In la Caserne de St. Elizabeth at Brussels, after the battle of Waterloo, the number of protrusions of the viscera, which fell under my notice, were much more considera- ble, than what I previously had any idea of ever meeting with. I well remember, in my own part of the hospital, two protrusions of a large portion of the stomach ; three of the bladder ; and ten or twelve of the mesente- ry, omentum, or intestines. Whether a suture should be used, when the protruded intestine is wounded, is a subject which will be noticed in considering wounds of the intestines. Some of the exposed intestine may have mortified before the arrival of surgical assist- ance. In eases of wounds, this event is/are ; but in those of stranzulated hernias it is not Vos. II „ 85 U73 uncommon. The treatment is explained in the article Hernia. When the protruded intestine is in a state of inflammation, its immediate reduction is r beyond all dispute, the means most likely to set every thing right. Even when tiie in- flammation is considerable, a timely reduc- tion of the displaced part, and the employ- ment of antiphlogistic means, will often pre- vent gangrenous mischief. The dull, brown, dark red colour of the intestine may induce the practitioner to suppose, either that the part is already mortified, or must inevitably become so, and consequently, he may delay returning it into its natural situation. But notwithstanding this suspicious colour of the intestine, its firmness will evince, that it is not in a state of gangrene. The ultimate recovery of a portion of intestine, so cir- cumstanced, is always a matter of uncer- tainty ; but the propriety of speedily repla- cing the part in its natural situation, is a thing most certain. “ Partes egressre sanee (observes Callisen) eitissime sunt reponendre, neque obstat mutatio coloris nativi in rubrum subfuscum.” (Sysl. Chir. Hod. T. \,p. 703, edit. 1798.) In case the bowel mortify after its reduction, all hopes of the preservation of life are not to be abandoned ; as I have no ticed in the articles Anus, artificial, ami Her- nia, in which last part of the book, many things, necessary to be known, concerning the mode of reducing protruded omentum, will also be found. When a piece of intestine cannot be re- duced, granulations and new skin sometimes grow over it, and a cure follows, as the ex- perience of Callisen confirms. (Op. cit. p. 706.) The protruded viscera having been re- duced, the next object is to retain them in the abdomen, until the wound is completely healed. When the wound is small, this is a matter of no difficulty ; for it is enough to put the patient in a position which will re- lax the fibres of the wounded muscles, while the edges of the wound are maintained in contact with sticking-plaster, and supported by a compress and bandage. Costiveness is to be removed by the mildest purgatives, such as the oleum ricini, or by laxative clys- ters, which are still preferable. But in cases of extensive wounds, even when the treat- ment is conducted with all possible judg- ment, it is occasionally difficult, and even impossible, to hinder the protrusion of the bowels by common dressings and a ban- dage. In this circumstance the edges of the wound must be sewed together. (See Gastroraphe.) In modern times, however, su- tures are much more seldom employed than formerly, and in the above article, some re- marks are offered, proving that the generality of wounds of the abdomen do not require the practice. When the omentum protrudes, and is strangulated by the narrowness of the open- ing, it soon contracts adhesions to it, unless speedily reduced. Should such connexion be already formed, when the surgeon is first consulted*, we are advised to cut off the por- 674 WO USD'S. tion which exceeds the level of the integu- ments, and to leave the rest in the wound. The latter will block up the opening, and have the good effect of preventing hernia. (Richer and, JYosogr. Ch%r. T. 3, p. 339, edit. 4.) When the protruded omen- tum is sound and free from adhesions, it ought to be reduced without delay. But, when the protrusion is large, and there is reason to fear, from the vomiting and the pains shooting frdrn the wound to the epigas- tric region, that the stomach is dragged, the displac ed part must be made free, and if sound, reduced. Should it be in a mortified state, the dead part must be previously cut away, and any vessels which bleed, tied separately with a piece of fine thread, or silk, both ends of which may either be cut off close to the knot, and the part then reduced; or one end of the silk may be left out of the w r ound, and the other cut away. Practition- ers who apprehend ill effects from leaving within the abdomen so small a particle of extraneous matter, as the little knot of fine thread, will prefer the last method, and wilh- dravv the ligature altogether, as soon as it becomes loose. Extravasation in the Abdomen. — Wounds of the abdomen may be complicated with extravasations of blood, chyle, excrement, bile, or * urine. None of these complica- tions, however, are half so frequent, as an inexperienced practitioner would apprehend. The employment of the phrase cavity of the abdomen has paved the way to much er- roneous supposition upon this subject, and has induced many absurd notions, which even the sensible observations, long ago pub- lished by J. L. Petit, have scarcely yet dis- pelled. As a modern writer has observed : “ There is not truly any cavity in the human body, but all the hollow bowels are filled with their contents, all the cavities filled with their hollow bowels, and the whole is equal- ly and fairly pressed. Thus, in the abdomen, all the viscera are moved by the diaphragm and the abdominal muscles upwards and downwards, with an equable coutinuai pres- sure, which has no interval ; and one would be apt to add, the intestines have no repose, being kept thus in continual motion ; but though the action of the diaphragm, and the reaction of the abdominal muscles are alter- nate, the pressure is continual; the motion which it. produces, (they produce) is like that which the bowels have, when we move them forwards in walking, having a motion, with respect to space, but none with regard to each other, or to the part of the belly which covers them ; the whole mass of the bowels is alternately pressed, to use a course illustration, as if betwixt two broad boards, which keep each turn or intestine in its right place, while the whole mass is regularly moved. When the bowels are forced down by the diaphragm, the abdominal muscles recede : when tbe bowels are pushed back again, it is the reaction of the abdominal mus- cles, lhatforces thembackand follows them ; there is never an instant of interruption of this pressure, never a moment, in which the bow els do not press against the peritoneum ; nor is there the smallest reason to doubt that the same points in each are continually opposed We see that the intestines do not move, or, at least, do not need to move in performing fheir functions; for in hernia, where large turns of intestines are cutoff by gangrene, the remaining part of the same intestines is closely fixed to the groin, and yet the bow- els are easy, and their functions legular. We find the bowels regular, when they lie out of the belly, in hernia, as v\ hen a certain turn of intestine lies in the scrotum or thigh, or in a hernia of the navel ; and where yet they are so absolutely fixed, that the piece of intestine is marked by the straitness of the rings. We find a person, after a wound of the intestine, having free stools for many days ; ant) what is it that prevents the feces from escaping but merely this regular and universal pressure ? We find a person, on the fourth or fifth day, with feces coming from the wound ! a proof, surely, that the wound of the intestine is still opposite or nearly opposite to the external wound. We find the same patient recovering without one bad sign ! What better proof than this could we desire, that none of the feces have exu- ded into the abdomen ? “ If in a wound of the stomach, the food could get easily out by that wound, tbe sto- mach would unload itself that way, there would be no vomiting, the patient must die; but so regular and continual is this pressure, that the instant a man is wounded in the stomach, he vomits, he continues vomiting for many days, while not one particle es- capes into the cavity of the abdomen. The outward wound is commonly opposite to that of the stomach, and by that passage, some part of the food comes out ; but when any accident removes the inward wound of the stomach from the outward wound, the ab- dominal muscles press upon the stomach, and follow it so closely, that if there be not a mere laceration extremely wide, this pres- sure closes the hole, keeps the food in, ena- bles the patient to vomit, and not a particle, even of jellies, or soups, is ever lost, or goes out into the cavity of the belly. i: How (proceeds Mr. J. Bell) without this universal and continual pressure, could the viscera be supported ? Could its ligaments, as we call them, support the weight of the liver ? Or what could support the weight of the stomach when filled ? Could the mesen- tery, or omentum, support tbe intestines ; or could its own ligaments, as we still name them, support the womb ? How, without this uniform pressure, could these viscera fail to give way and burst ? How could the cir- culation of the abdomen go on ? How could the liver and spleen, so turgid as they ate with blood, fail to burst ? Or what possibly could support the loose veins and arteries of tbe abdomen, since many ot them. e g. the splenic vein, is (are) two feet in length, is (are) of tbe diameter of tbfe thumb, and has (have) no other than the common pellucid and delicate coats of the veins ? How could WOUNDS. 675 (be viscera of Ibe abdomen bear shocks and falls, if hot supported by the universal pres- sure of surrounding parts ? In short, the acci- dent of hernia being forced out by any blow upon the belly, or by any sudden strain, ex- plains to us how perfectly full the abdomen is, and how ill it is able to bear any pressure, even from its own muscles, without some point yielding, and some one of its bowels being thrown out. And the sickness and faintness, which immediately follow the drawing off of the waters of a dropsy ,«explain to us, what are the consequences of such pressure being even for a moment relaxed. But, perhaps, one of the strongest proofs is this, that the principle must be acknowledged, in order to explain what happens daily in wounds ; for though in theory ive should be inclined to make this distinction, that the hernia, or abscess of the intestines will ad- here and be safe, but that wounded intes- tines, not having time to adhere, will be- come flaccid, as we see them do in dissec- tions, and so, falling away from the external wound, will pour out their feces into the ab- domen, and prove fatal ; though we should settle this, as a fair and good distinction in theory, we find that it will never answer in practice. Soldiers recover daily from the most desperate wounds ; and the most likely reasons, that we can assign for it, are the fulness of the abdomen, the universal, equa- ble, and gentle pressure ; and the active dis- position of the peritoneum, ready to inflame with the slightest touch. The wounded in- testine is, by the universal pressure, kept close to the external wound, and the perito- neum and the intestine are equally inclined to adhere. In a few hours, that adhesion is begun, which is to save ‘he patient’s life, and the lips of the w r ounded intestine are glued to the lips of the external wound. Thus is the side of the intestine united to the inner surface of the abdomen ; and though the gut casts out its feces, while the wound is open ; though it often casts them out more freely, while the first inflammation lasts; yet the feces resume their regular course, whene- ver the wound is disposed to close.” (John Bell's Discourses on Wounds, p. 323, 327, Edit. 3.) The loregoing extract, though drawn up in a careless style, contains such observa- tions as are well calculated to make the reader understand, that the abdomen is in reality not a cavity, but a compact mass of containing and contained parts ; that the close manner, in which the various surfaces are constantly in contact most powerfully oppose extravasations ; and that, in fact, it often entirely prevents them. The passage cited impresses us with the utility of that quick propensity to the adhesive inflamma- tion, which prevails throughout every peri- toneal surface, and which not only often has the effect of permanently hindering effusion of the contents of the viscera, by agglutinating the parts together, but which, even when an extravasation has happened, beneficially confines the effused blood in one mass, and surrounds it with such adhesions of the parts to each other, as are rapid in their formations, and effectual for the purposes of limiting the extent qf the effusion, and preventing the irritation of the extravasa- ted matter from affecting the rest of the ab- domen. It is to Petit that surgeons are indebted for more correct modes of thinking upon the foregoing subject, and it is with great plea- sure that I here refer to his valuable obser- vations. (See Mem. de I'Acad. de Chir.) But notwithstanding the reciprocal pres- sure of the containing and contained parts against each other, and the useful effect of the quickly arising adhesive inflammation, in all penetrating wounds of the belly, com- plicated with injuries of the viscera, we are not to suppose, that extravasation never happens ; but only that it is much less fre- quent than has been commonly supposed. Mr. Travers, with much laudable industry, has endeavoured to trace more minutely, than any preceding writer, the particular circumstances, under which effusions in the abdomen are likely or unlikely to hap- pen.” It being admitted (says he) tbat there are cases in which effusion does take place, it is easy to conceive circum- stances which must considerably influence this event. If, for example, the stomach and bowels be in a state of emptiness, the nausea which follows the injury will maintain that state. If the extent of the wound be con- siderable, the matter will more readily pass through the wound, than along the canal. A wound of the same dimensions in the small and large intestines, will more readily evacuate the former than the latter, because it bears a larger proportion to the calibre. Incised and puntured wounds admit of the adhesion of the cut edges, or the eversion of the internal coat of the gut, so as to be in many instances actually obliterated ; where- as lacerated, or ulcerated openings, do not admit of these salutary processes. Again, in a transverse section of the bowel, contrac- tion of the circular fibre closes the wound, whereas in a longitudinal section, the con- traction of the fibre enlarges it. Such (says Mr. Travers) are the circumstances, which combined, in a greater or less degree, in- crease or diminish the tendency to effu- sion.” (On Injuries of Intestines , §*c. p. 13, 14.) After the details of some experiments and cases, the preceding author makes, among other conclusions, the following : 1. That effusion is not an ordinary conse- quence of penetrating wounds. 2. That if the gut be full and the wound extensive, the surrounding pressure is over- come, by the natural action of the bowel tending to the expulsion of its contents. 3. That, if food has not recently been taken, and the wound amounts to a division of the gut, or nearly so, the eversion and contraction of the orifice of the tube prevent effusion. 4. That if the canal be empty at the lime of the wound, no ^subsequent state of the bowel will cause effusion, because the super- VJTOUA'DS. vening inflammation agglutinates the sur- rounding surfaces, and forms a circumscribed sac ; nor can effusion take place from a bowel at the moment full, provided it retains a certain portion of its cylinder entire, the wound not amounting nearly to a semidivi- sion of the tube, for then the eversion and contraction are too partial to prevent an extravasation. 5. That, when however air has escaped from the bowel, or blood has been extrava- sated in quantity within the abdomen at the time of the injury, the resistance, made to effusion, will be less effectual, although the parietal pressure is the same, as such fluids will yield more readily, than the solids na- turally in contact. (P. 25, 26, 100.) “ That, though extravasation is not com- mon in penetrating wounds, it follows more generally in cases, where the bowel is ruptured by blows, or falls upon the belly, while the integuments continue upwounded. (P. 36.) 7. That when the bowels are perforated by ulceration, there is more tendency to effusion, than in cases of wounds. (P. 38, fee.) Mr. Travers attempts to explain the reason of the greater tendency to effusion, in cases of intestine burst by violence, than in those of ulceration, “by the difference in the na- ture of the injury, which the bowel sustains, when perforated by a sword or bullet, as in the one case, or burst or ulcerated in the other. A rupture by concussion could only take place under a distended state of the bowel, a condition most favourably to effu- sion, and from the texture of the part, a rup- ture so produced would seldom be of limited extent. The process of ulceration, by which an aperture is formed, commences in the in- ternal coat of the bowel, which has always incurred a more extensive lesion, than the peritoneal covering. The puncture, or cut, is merely a solution of continuity in a point, or line ; the ulcerated wound is an actual loss of substance. The consequence of this difference is, that, while the former, if small, is glued up by the effusion from the cut ves- sels, or, if large, is nearly obliterated by the full eversion of the villous coat, the latter is a permanent orifice ” (P. 46.) How much Mr. Travers and Mr. John Bell differ in opinion, upon these latter points, will appear from th^s following^as- sage : after adverting to the adhesion, which takes place between the viscera and the peritoneum, under a variety of circumstances attending disease, Mr. John Bell observes : “ This it is, which makes the chief difference, in point of danger, betwixt an ulcerated and a wounded intestine ; for, in a wound, there is, as we should suppose, no time for adhe- sion, nothing to keep the parts in contact, no cause, by which the adhesion might be pro- duced. But, in an ulcer, there is a slow dis- ease, tedious inflammation, adhesion at first, and abscess, and bursting afterward j some- times a fistula remains discharging feces, and sometimes there is a perfect cure. If a nut- shell, a large coin, a bone, or any dangerous thiqg be swallowed, i( stops in the stomach, cadsing swelling and dreadful pain ; at last, a hard firm tumour appears, and then it sup- purates, bursts, the bowel opens, the food is discharged at every meal, till the fistula gradually lessens, and heals at last. But where the stomach is cut with abroad wound of a sabre, the blood from the wounded epiploic vessqjs, or the food itself, too often pours out into the abdomen, and the patient dies,'&ic.” ( Discourses on Wounds, p. 321, edit. 3.) The author afterward proceeds to explain, how in cases of penetrating wounds, the compact state of the containing and con- tained parts, and the incessant and equable pressure, which the viscera sustain, fre- quently hinder effusion. Which of these gentlemen is most correct, I cannot pretend to determine, and whether Mr. Travers’s cases are deviations from what is most comraoh, can only be decided by a comparative examination of a greater num- ber of facts. When the intestines ulcerate, and thus rid themselves of foreign bodies, the general tenor of the cases on record un- doubtedly affords us little reason to be ap- prehensive of extravasation. Yet, with re- spect to ulceration of the intestines from other causes, circumstances may be very different. And it is but justice to state, That Mr. Travers’s opinions have received some confirmation from an interesting case, pub- lished by Dr. J. Crampton, of Dublin. It is an instance of rupture of the stomach, and fatal effusion of its contents into the cavity of the abdomen. The patient was a young lady, aged 29. She was suddenly'fhken ill with spasm in her stomach, and other severe symptoms, and died in about twelve hours. “ On opening the abdomen, the stomach was observed to be pale, flaccid, and empty. Its contents, among which were recognized oat- meal and castor oil, had escaped into the cavity of the abdomen, through a round aperture situated on its anterior surface, at the union of the cordiac and pyloric portions. This perforation of the stomach was perfectly circular, about the size of a pea, and appeared to be the result of an ulcer on the mucous surface, which had gradually penetrated the other coats. This ulcer was hollow and circular, nearly the size of a shilling, and had the appearance, as if it had been made with caustic, with the orifice in its centre.” (J. Crampton , Med. Chir. Trans. Vol. 8, p. 230.) To the prece- ding, Mr.Travers has annexed some addition- al facts : one is an example of a rapidly fatal effusion of the intestinal contents, through an ulcerated opening nbout a finger’s breadth below the pylorus. The foramen had a peritoneal margin, and proved to bo the centre of an irregular superficial ulcer of the mucous coat. Another case is that of a similar ulceration of ( the small intestines, and fatal extravasation of their contents. In another example, a circular aperture ot the peritoneum, large enough to admit a crow’s quill, was found after death at the junction of the duodenum and stomach. It also was the centre of an ulcer, that had destroyed Ike villous and muscular coals oi the bowel to ..the extent of half an Inch, lor many other ingenious observations, I must refer the reader to Mr. Travers’s paper, who con- cludes with remarking, that the chief diag- nostic symptoms of these hopeless cases ap- pear to be : 1. Sudden, most acute, and unremitting pain, radiating from the scrobiculus cordis, or the navel, to the circumference of the trunk, and even to the limbs. A peculiar pain, the intensity of which, like that of par- turition, absorbs the whole mind of the pa- tient, who, within an hour from the enjoy- ment of perfect health, expresses his serious •i and decided conviction, that if the pain be v not speedily alleviated, he must die. ^ Coeval with the attack of pain, remark - f able rigidity and hardness of the belly, from a fixed and spastic contraction of the abdo- i minal muscles. 3. A natural pulse for some hours, until the symptoms are merged in those of acute peritonitis, and its fatal termination in the adhesive stage. (Med. Chir. Trans. Vol. 8, p. 231, et seq.) * Blood is more frequently extrayasated in the abdomen, than any other fluid, but, it does not always take place, Unless the | wounded vessels be above a certain rnagni- | tndfr. The compact state of the abdominal ■' viscera, in regard to each other, and their f action on each other, oppose this effect. I The action alluded to, which depends on the abdominal muscles and diaphragm i3 rendered very manifest by what happens in consequence of operations for hernias, at- tended with alteration of the intestines, or omentum If these viscera burst, or suppu- rate, after being reduced, the matter which escapes from them, or the pus which they secrete, is not lost in the abdomen -, but is propelled towards the wound in the skin, and there makes its exit The intestinal mat- ter effused from a mortified bowel, has been known to remain lodged the whole inter- val, between one time ot dressing the wound and another, in consequence of the surgeon stopping up the external wound with a large tent. When the above-mentioned action or pressure of the muscles, is not sufficient to keep the blood from making its escape from the vessels, still it may hinder it from be- coming diffused among the convolutions of the viscera, and thus theSextravasation is confined in one mass. The blood, effused and accumulated in this way, is commonly lodged at the inferior and anterior part of the abdomen, above the lateral part of the pubes, and by the side of one of the recti ' muscles. The weight of the blood may l propel it into this situation, or perhaps, there may be less resistance in this direction, than ! in others. In opening the bodies of persons, x«ho have died with such extravasations, things may put on a different aspect, and j the blood seem to be promiscuously extra- 1 vasated over every part of the abdomen. But, when such bodies are examined with care, it will be found, that the blood does i not insinuate itself among the viscera, till the moment when the abdomen is opened, and the masy previously lies in a kind ot’ pouch. This pouch is frequently circum- scribed, and bounded by thick membranes, especially when the extravasation has been of some standing. (Sabatier Medecine Opt' ratoire , T. l,p. 28 — 30.) Every practical surgeon should remember well that all the abdominal viscera closely touch either each other, or the inner surface of the peritoneum. This is one grand reason, why extravasations are seldom extensively diffused ; but, commonly lie in one mass, as Petit, Sabatier, and all the best moderns have noticed. The pressure of the elastic bowels, diaphragm, and abdominal muscles, not only frequently presents an obstacle to the diffu- • sion of extravasaied matter, but often serves to propel it towards the mouth of the wound. The records of surgery furnish numerous instances, in which persons have been stab- bed through the body, without fatal conse- quences, and sometimes without the symp- toms being even severe. In Mr. Travers’s publication many ( cases, exemplifying this ob- servation, are quoted from a Variety of sources: Fab. Ilildan. Obs. Chirurg. Cent, 5. Obs. 74. CEuvres de Pare, liv. 10. Chap. 35. Wiseman’s Surgery, p. 371. La Motte’s Traite Complet de Chirurgie, &c. &.c. In such cases, the bowels have been supposed to have eluded the point of the weapon, and, perhaps, in a few instances, this may actually have been the fact ; but, in the generality of such examples, the bowels must have been punctured, and the extravasation of intes- tinal matter prevented by the pressure of the viscera against each other. The pouch, or cyst, in which the extrava- sated blood, or matter, lies, as mentioned by- Sabatier, is formed by the same process, which circumscribes the maiter of abscesses. (See Suppuration.) It is, in short, the adhe- sive inflammation. All the surfaces in con* tact with each other,' and surrounding the extravasation, and traffk of the wound, ge- nerally become so intimately connected to- gether by the adhesive inflammation, that the place, in which the extravasation is lodged, is a cavity entirely destitute of ail communication with the cavity of the peri- toneum. The track of the wound leads to the seat of the effused fldld, but has no distinct opening into the general cavity of the abdomen. The rapidity, vith which the above adhesions frequently form, is almost incredible. It should be known, however, that extra- vasations are occasionally diffused in various degrees among the viscera, owing to the patient being subjected to a great deal of motion, or affected with violent spasmodic contractions of the intestines. Urine and bile are also generally dispersed to a great extent. As for blood, its disposition to coagulate must often tend both to stop fur- ther hemorrhage, and confine the extravasa- tion in one mass. Symptoms and Treatment of Extravasations in the Abdomen. 1. Blood - — Wounds of the ,spleen, and of very large veins and arteries WOUNDS- 4 S in the abdomen, almost always soon prove fatal from internal hemorrhage. The blood generally makes its way downwards, and accumulates at the inferior part of the ab- domen, unless the presence of adhesions happen to oppose the descent of the fluid to the most depending situation. The bidly swells, and a fluctuation is perceptible. The patient grows pale, loses his strength, is affected with syncope, and his pulse be- comes weak, and scarcely distinguishable. In short, the symptoms usually attendant on profuse hemorrhage are observable. As the viscera and vessels in the abdomen are compressed on all sides by the surrounding parts, the blood cannot be effused without * overcoming a certain degree of resistauce ; and unless a vessel of the first magnitude, like the aforta, the vena cafa, or one of their principal branches, has been wounded, the blood escapes from the vessel slowly, and several days elapse, before any consi- derable quantity accumulates. In these cases, the symptoms, which per- haps bad disappeared under the employ- ment of bleeding and anodyne medicines, now recur. A soft fluctuating tumour may be felt at the lower part of the abdomen ; sometimes on the right side ; sometimes on the left ; but occasionally on both sides. The pressure made by the effused blood, on the urinary bladder, excites distressing incli- nations to make water ; while the pressure, which the sigmoid flexure of the colon suffers, is the cause of obstinate constipa- tion. In the mean time, as the quantity of extravasated blood increases, the. perito- neum inflames. The pulse grows weaker ; debility ensues ; -the countenance becomes moistened with cold perspirations ; and according to some w riters, unless the sur- geon practise an incision for the discharge of the fluid, the patient falls a victim to the accident In the year 1733, Vacher adopted this treatment with success. Petit afterward tried the same plan, though it did not an- swer, (as is alleged) in consequence of the inflammation having advanced too far before the operation w'as performed. Long before the time of Vacher and Petit, a successful instance of similar practice was recorded by Cabrole, in a work which this author pub- lished, under the title of A\y*(Znrov ctvetro/ui- xsv, id est, Anatbmes elenchus accuratissi- mus, omnes humani corporis partes ea qui solent secari methodo, delineans. Accessere osteologia, observationesque Medicis ac Chirurgicis perutiles. Geneva* 1604. The method pursued by Vacher, was therefore not so new as Petit imagined. Indeed, w^hen the symptoms leave no doubt, of there being a large quantity of blood extravasated in the abdomen ; when the patient’s complaints are of a very serious nature, and are evidently ow ing to the irri- tation and pressure of the blood on the surrounding viscera ; and when a local swelling denotes the seat of the extravasa- tion-, there cannot he two opinions about, the propriety of making an incision for its eva= cuation. Surgeons should recollect, however, that if no opening be made, a small extravasation of blood may not produce any considerable irritation. On the contrary, when the cyst including the blood is opened, the air then has access, and that part of the fluid which cannot be discharged, putrifies and becomes so irritating, as to be a true cause of inflam- mation. The bad symptoms are also some- times chiefly owing to the injury done to parts within the abdomen, and still more commonly to inflammation within that ca- vity, arising rather from the wound than from the presence of effused blood. On the whole, I am disposed to join a late waiter in the belief, that the practice of discharging extravasated blood from the abdomen can rarely be adviseable — (See Htnneris Mil, Surgery , P. 412, erf. 2.) 2. Chyle and Feces. — These are not so easily extravasated in the abdomen as blood, because they do not require so much resist- auce, on the outside of the stomach and intestines, to make them continue their na- tural route through the alimentary canal, as blood requires to keep it in the vessels. However, when the wound is large, aud the bowel distended at the moment of the injury, or when, as Mr. Travers has explain- ed, air is extravasated, or blood effused in the abdomen, which fluids are incapable of making effectual resistance to the escape of the intestinal matter, the latter may be ef- fused. (See an Inquiry into the Process of JYature in repairing Injuries of the Intestines , fyc.p. 26.) Nothing is a better proof of the difficulty, with which chyle and feces are extravasated, than the operation of an emetic, when the stomach is wounded and full of aliment. In this instance, if the re- sistance to the extravasation of the contents of the stomach were not considerable, they would be effused in the abdomen, instead of being vomited up. A peculiarity in wounds of the stomach and intestines is, that the opening, which allows their contents to escape, may also allow them to return into the wounded viscus. Extravasation of intestinal matter in the abdomen is attended with severe febrile symptoms; considerable pain and swelling of the belly ; convulsive startings ; and hic- cough and vomiting, with which the patients are generally attacked the day after the re- ceipt of the wound. ( Sabatier , Mtd. Optra- toirc , T. 1 ,p. 34.) In these cases, only general means can be employed ; venesection, leeches, fomen- tations, low diet, perfect rest, anodynes, he. All solid food must be strictly prohibited. If pressure can be borne without inconve- nience, as is sometimes the case in the early stage, the close state of the viscera may bo increased by the application of a bandage round the body. If the symptoms arc not speedily assua- ged, the inflammation spreadsover the whole cavity of thc;)bdomcn, gangrenous Mischief WOUNDS. : akes place, and the patients die in the course of a lew days. 3. Bile — Bile, on account of its great fluidity, is more apt to be widely extravasa- ted in the abdomen, than either blood, or the ( contents of the stomach aud intestines. However, on account of the small size of the gad bladder, and its deep guarded situa- tion, between the concave surface of the i liver, and upper part of the transverse arch of the colon, wounds of it are uncommon. Sabatier informs us, that he has only been able to find one example on record. This case was communicated to the Royal Socie- ty of London, by Dr. Stewart (No. 414, | pag. 341. Abridgm. Vol. 7, pag. 571 — 572,) A wound penetrated the cavity of the abdo- men, and entered the fundus of the gall p bladder, without doing any material injury [ to the adjacent parts. The abdomen was I immediately distended, as if the patient had | been afflicted with an ascites, or tympanitis ; ? nor did the swelling either increase or di- minish, till the patient’s death, which hap- | pened in a week. i Though there was a great deal of tension, I there was no rumbling noise in the abdomen. ! No stools, and very little urine were dis- I charged, notwithstanding purgatives and I clysters and a good deal of liquid nourish- f ment, were given. Anodynes failed to i; 1 procure one instant of sound sleep, and tile patient was incessantly in a most restless state. There was no appearance of fever, ' and the pulse was always natural till the last | day of the patient’s life, when it became 1 intermittent. After death, the intestines ® were found much distended, the gall bladder v quite empty, and a large quautity of bile 5 extravasated. Sabatier had an opportunity of noticing the symptoms of an extravasation of bile, in consequence of a wound of the gall blad- der. The patient’s abdomen swelled very quickly ; his respiration became difficult, and he soon afterward complained of tension and pain in the right hypochondrium. His pulse was small, frequent, and contracted ; his extremities were cold, and his counte- nance very pale. The bleedings which were practised the first day, gave him a little relief ; but the tension of the abdomen, and the difficulty of breathing, still continu- ed. A third bleeding threw the patient into the lowest state of weakness, and he vomit- ed up a greenish matter. On the third day, ; the lower part of the belly was observed to be more prominent, and there was no doubt of an extravasation. Sabatier introduced a trocar, and gave vent to a green blackish ' fluid, which had no smell, and was pure bile ! that had escaped from the wound of the gall bladder. After the operation, the pa- tient grew weaker and weaker, and died in I a few hours. On opening the body, a large quantity of yellow bile was found between the peritoneum and intestines ; but it had not insinuated itself among the convolutions 1 of the viscera. A thick gluten connected the bowels together, and they were prodi- ji giously distended. The gall bladder was shrivelled, and almost empty. Towards its fundus, there was a wound, about a line and a half long, corresponding to a similar wound in the peritoneum. The wound which had occurred at the middle and lower part of the right hypochondrium, between the third and fourth false ribs, had glided from behind forward, and from above downward, between the cartilages of the ribs, until it reached the fundus of the gall bladder. Sabatier takes notice, that the symptoms of the two cases, which have just now been related, were very similar. Both the patients 1 were affected with an exceedingly tense swelling of the belly, unattended with pain, or borborygmus, and they were both obsti- nately constipated. Their pulse was ex- tremely weak the latter days of their indis- position, and they were afflicted with hic- cough, nausea, and vomiting. Sabatier seems to think one thing certain, viz. that wounds of the gall bladder attended with effusion of bile, are absolutely mortal, and that no operation can be of any avail. ( Mddecine Operatoire, T. 1 ,p. 34 — 37.) A contrary inference, however, may be drawn from a case, detailed by Parois^g, in. which a bullet had lodged in the gall bladder two years. (Opuscules de Chir. p. 255.) The recovery published by Mr. Fryer, of Stam- ford, tends also to prove, that every effusion of bile is not unavoidably fatal. A boy, about thirteen years old, received a violent blow from one of the shafts of a cart, on the region of the liver. The injury was succeeded by pain, frequent vomiting of bilious matter, great sinking, coldness of the extremities, and a weak, small, fluttering pulse. The belly was fomented, and pur- ging clysters thrown up. On the third day, symptoms of inflammation began, attended with considerable pain about the liver, great tension and soreness of the abdomen, and frequent vomiting. The pulse was quick, small, and weak ; the skin hot and dry; the tongue mucii furred ; the urine high-colour- ed ; and there was some difficulty of breath- ing ; and great thirst. Eigh^ ounces of blood were taken away, the fomentations continued, and a few grains of calomel were directed to be given every four hours until the bowels were properly opened. After- ward, the effervescing mixture, with ten drops of laudanum, was exhibited every four hours. On the following day, the patient had some motions, and was much better; but, as his sickness continued, he was ordered a grain of opium every four hours. About a week afterward, he complained of a great increase of pain, which was Bomewhat re- lieved by a blister. He was now completely jaundiced, and his stools were white, but the tension, pain, and sickness were abated. Two days afterward, a fluctuation was perceived in the abdomen, which, in another week, became considerably distended with fluid. The patient did not now complain of much pain ; but appeared to be sinking fast ; a puncture was made in the swelling, and woL\m- ti&Q thirteen pints of what appeared to be pure bile were evacuated. The bowels then soon became regular, and the appetite good. In twelve days, the operation was repeated, and fifteen pints of the same bilious fluid were drawn oft'. Nine days afterward, an- other punctune was made, and thirteen pints more let out ; and six were discharged in an- other fortnight. From this period the boy went on well, and perfectly recovered un- der the use of light tonic medicines. (See Med. Chir. Trans. Vol. 4, p. 330.) A previous accidental adhesion of the galWuadder to the peritoneum might also prevent the extravasation of bile, and its tiangerous effects. ( Callisen , Syst. Chir. Homtrnoe. T. 1.^.718.) According to Dr. Hennen, a deep wound of the liver is as fatal as if the heart itself was engaged. The slighter injuries are re- coverable. He states, that the usual symp- toms of a wound of the liver are yellowness of the skin and urine ; derangement of the alimentary canal, and great and distressing itching of the skin. The discharge from the wound is generally yellow and glutin- ous . though sometimes either serous, or like^, unraixed bile. (On Militai'y Surgery, Ed72^p. 429.) For some other interesting observations on wounds of the liver, I have great pleasure in referring to the latter work. (See akfo Wedekind de Vulnere Hcpatis C'ura- io, Jence, 1735 ; and Thomson's Report of Obs . made in the Military Hospitals in Bel- gium , 8ro. 1816.) 4. Urine. — Urine being of a very fluid nature, may, like the bile, be extensively diffused in the abdomen, when the bladder is wounded at any part, connected with the peritoneum. If, in this kind of case, the urine be not drawn off with a catheter, so as to prevent its extravasation, the patient soon perishes. Many instances are recorded of the bladder being injured even by gun- shot wounds, which were not mortal. Wounds of the bladder are attended with a discharge of bloody urine and difficulty of making water. They are always dan- gerous cases, both on account of the risk of the effusion of so irritating a fluid in the abdomen, and of the chance of extravasa- tion in the cellular membrane. Under proper treatment, however, they often ad- mit of cure. (See Gunshot Wounds.) If possible, the elfused fluid should be dischar- ged by a depending posture, or suitable punctures, or incisions, and the recurrence of extravasation prevented by the introduc- tion of a catheter, which is to be left in the urethra. The patient must also be allowed little drink. As for the tension and pain of the belly, the common attendants of a wounded bladder, they may be greatly re- lieved by the use of the warm bath, ( Calli - sen, T. 1, p. 719.) bleeding, low diet, and other antiphlogistic means not being omit- ted. Wounds of the Stomach. — As Dr. Hennen has observed, these cases are extremely dangerous, though not always mortal. 91 Baron Percy calculates, that of twenty cases, four or live onTy have escaped ; this.* however, is a most favourable average.' * Two cures of wounds of the stomach are reported by Dr. Thomson. (Obs. made in the Military Hospitals in Belgium, fyc.) With respect to the chances of recovery, Dr. Hennen justly remarks, that, in the histories of the Bohemian, Prussian (D. Beckher de Cultriroro Prussiaco, 12wo. Lugd. 1638,) and English u Cultri-sores,” in some of whom the knives have been cut out, and in others, discharged spontaneously through the coats of the stomach and parietes of the abdomen, are very encouraging. Hevin has collected^ many instances of recovery both from in- cised and gunshot wounds of the stomach. (Mem. de VAcad. de Chir. T. 1.) But, ac- cording to Dr. Hennen, Ploucquet, in the articles “ Ventriculus” and “ Pantophagi,” has brought together the largest number of cases. Dr. Hennen, also refers to Loie * thorpe's Abridgment of the Phil. Trans. Vol. 6, p. 192, for instances, in which the sto- mach of a horse was wounded and sewed up, and the same practice extended to the human subject, with success. It appears | also from the “ Annales de Literature,” &c. T. 2, by Kluyskens, from Sehlichting’s “ Iraumatologia,” and the “ Bulletin de la Faculty," fyc. Tom. 5 ,p. 386, that wounds of the human stomach have been stitched with success in various cases of recent date. (See Hennen' s Military Surgery, Ed. 2, p. 438 ) As the latter author observes, wounds of the stomach not unfrequently become fistulous and remain open. In a case, re- corded by Richerand. the fistula continued open nine years ; and in another instance, related by Ettmuller, ten years. (De Vul- nere Ventriculi Programme, l dp. 1730.) And Wencker has detailed a case, in which the opening continued twenty-seven years. (See Halteri Dissert. Chir. Vol. 5, art. 19. V For farther information, connected witn this subject, the reader may also consult, Jungen, de Lethalitate Vulnerum Ventriculi, Helmsl. 1751 ; and Ludov. Horn, de Ventri- culi Ruptura, 8 vo Berol. 1817. Also Med, Chir. Journ. Vol. 5, p. 72. Wounds of the Intestines. — The vomiting of blood, or discharge of it by stool ; the escape of fetid air, or of intestinal matter, from the mouth of the wound ; an empty collapsed state of a portion of bowel, pro- truded at the opening in the skin, are the common symptoms attending a wound of this kind. When the wound is situated in the prolruded portion, it is obvious to the surgeon’s eye ; but when it affects apart of the intestinal canal within the abdomen, the nature of the case can be known only by a consideration of other symptoms. In addi- tion to such as I have already described, there are some others, whicli ordinarily accompany wounds of the bow’els ; as, for instance, oppression about the proecordia, acute or griping pain in the belly, cold sweats, syncope, &.c. But, unless the wounded intestine protrude, there is no ractical good in knowing whether the owel is Injured or not, since, if it be in. the WOUNDS ’abdomen, the treatment ought not to be materially different from that of a simple penetrating wound of the belly, unattended with a wound of any of the viscera. Large wounds of the small intestines, particularly of the duodenum and jejunum, are attended with acute fever, anxiety, paleness of the countenance, syncope, cold perspirations, a small, intermitting, tremulous pulse, and they frequently prove fatal. Injuries of the small intestines are also more otten, than those of the large ones, followed by extra- vasation. A total division of the upper part of the intestinal canal, towards the pylorus, will deprive the body of the nourishment requisite for its support. If the chyle escape from the wound, the patient will die of a slow marasmus ; and if it become ex- travasated, it will be likely to excite such irritation as will prove fatal. The escape of excrement, or of fetid air from the wound, indicates an injury of one of the large in- testines. In these cases, the symptoms are generally milder, and the passage of the intestinal contents outward through the wound more easy, on account of the bowel being less moveable. For the same reason, the wounded intestine more readily con- tracts an adhesion to the adjacent parts. (Callisen, Sysl. Chirurgice Hoditrnte, T. 1, p. 717.) A wounded intestine is said to present some particular appearances, to which the generality of writers have paid no attention : u If a gut be punctured, the elasticity of the peritoneum, and the contraction of the muscular fibres, open the wound, and the villous, or mucous coat, forms a sort of her- nial protrusion, and obliterates the aperture. If an incised wound be made, the edges are drawn asunder, and reverted so that the mucous coat is elevated in the form of & fleshy lip. If the section be transverse, the lip is broad and bulbous, and acquires tume- faction and redness from the contraction of the circular fibres behind it, which produces, icelatively to the everted portion, the ap- pearance of a cervix. If the incision be according to the length of the cylinder, the lip is narrow, and the contraction of the ad- jacent longitudinal fibres, resisting that of the circular fibres, gives the orifice an oval form. This eversion and contraction are produced by that series of motions, which constitutes the peristaltic action of the in- testines.” ( Travers on Injuries of the Intes- tines, p. 85.) According to this gentleman, some of these appearances were described by Haller, in Element. Physiol, lib. 24, sect. 2 ; and Opera Minora , T. 1, sect. 15. Having witnessed the facility, with which considerable injuries of the intestinal tube were repaired, Mr. Travers was desirous of ascertaining more fully the powers of na- ture in the process of spontaneous repara- tion, and of determining, under how great a degree of injury it would commence, as well as the mode of its accomplishment. For these purposes, he divided the small intestine of several dogs as far as the mesen- Voji. II. 86 lory. All these animals died, in corise quence of the intestinal matter being extra vasated, if they had been lately fed, or if they had been fasting in consequence of in- flammation, attended with a separation of the ends of the divided bowel, eversion of the mucous coat, and obliteration of the cavity, partly by this eversion, and partly by a plug of coagulated chyle. In one particular instance, in which Mr. Travers made a division of the bowel, half through its diameter, a sort of pouch was formed round the injured intestine. “A pouch, resembling somewhat the diverti- culum in these animals, was formed opposite to the external wound, on the side of the pa- rietes, by the lining peritoneum, on the other side, by the mesentery of the injured intes- tine, that iqtestineitself,and an adjacentfold, which had contracted with it a close adhe- sion. The pouch, thus formed and insula- ted, included the opposed sections of the gut, and had received its contents, he. The tube, at the orifices, was narrowed by the half eversion, but ottered no impediment to the passage of fluids.” (P. 96.) Whether, under these circumstances, the functions of the alimentary canal could have been con- tinued, Mr. Travers professes himself inca- pable of deciding. Among the inferences, which this gentleman has drawn from the experiments, detailed in bis publication, the tendency of the two portions of a divided bowel to recede from each other, instead coalescing to repair the injury, merits no- tice, inasmuch as it tends to show, that the only means of spontaneous reparation con- sist in the formation of an adventitious canal, by the encircling bowels and their appendages. The everted mucous coat, which is the part opposed to the surround- ing peritoneum, is also indisposed to the ad- hesive inflammation. When, however, the wound of the intes- tine is smaller, the obstacles to reparation are not absolutely insurmountable. Here, retraction is prevented, and the processes of eversion and contraction modified by the limited extent of the injury. If, therefore, the adhesive inflammation unite the con- tiguous surfaces, effusion will be prevented, and the animal escape immediate destruc- tion. But, union can only take place through the medium of the surrounding parts. According to Mr. Travers, it is the re- traction, immediately following the wound, that is a chief obstacle to the reparation of the injury ; for, if the division be performed in such a way as to prevent retraction, the canal will be restored ia so short a time, as but slightly to interrupt the digestive func- tion. In confirmation of this statement, a ligature was tightly applied round the duo- denum of a dog, which became ill, but en- tirely recovered, and was killed. “ A liga- ture, fastened around the intestine, divides the interior coats of the gut, in this effect resembling the operation of a ligature upon an arfery. The peritoneal tunic alone maintains its integrity. The inflammation, WOUNDS which the ligature induces on either side of it, is terminated by the deposition of a coat of lymph, which is exterior to the ligature, and quickly becomes organized. When the ligature, thus enclosed, is liberated by the ulcerative process, it falls of necessity into the canal, and passes oft' with its contents.” (P. 103, 104.) It appears also from Mr. Travers’s experi- ments and observations, that longitudinal wounds of the bowels are more easily repair- ed, than such as are transverse. In a dog, a longitudinal wound, of the extent of an inch and a half, was repaired by the adhesive inflammation. Here the process of eversion is very limited ; the aperture bears a smaller proportion to the cylinder of the bowel ; and the entire longitudinal fibres resist the action of the circular, which ane divided, and can now only slightly lessen the area of the canal. (P. 108.) We come now to the consideration of the treatment of wounds of the intestines; a subject, in which much difference of opinion has prevailed ; principally, however, con- cerning the circumstances in which sutures are necessary, . and the most advantageous way of applying them. When the wounded bowel lies within the cavity of the abdomen, no surgeon of the present day would have the rashness to think of attempting to expose the injured intestine, for the purpose of sewing up the breach of continuity in it. In fact, the sur- geon seldom knows at first what has hap- pened ; and when the nature of the case is afterward manifested, by the discharge of blood per anum, an extravasation of intes- tinal matter, Sic. it would be impossible to get at the injured part of the bowel, not only because its exact situation is unknown, but more particularly on account of the ad- hesions, which are always formed with sur- prising rapidity. But, even if the surgeon knew to a certainty, in the first instance, that one of the bowels was wounded, and the precise situation of the injury, no suture could be applied, without considerably en- larging the external wound, drawing (he wounded intestine out of the cavity of the abdomen, and handling and disturbing all the adjacent viscera. Nothing would be mure likely, than such proceedings, to ren- der the accident, which may originally be curable, unavoidably fatal. 1 entirely agree upon this point with Mr. John Bell, who says, “ When there is a wounded intestine, which we are warned of only by the pass- ing out of the feces, we must not pretend to search for it, nor put in our finger, nor expect to sew it to the wound ; but we may trust that the universal pressure, which prevents great effusion of blood, and col- lects the blood into one place, that very pressure, which always causes the wounded bowel and no other to protrude, will make the two wounds, the outward wound and the inward wound of the intestine, opposite each other, point to point ; and if all be kept there qyiet, though but for one day, so lively is the tendency to inflame, that the adhesion will be begun, which is to save the patient’s life.” (Discourses on Wounds v 361, Edit. 3.) When the extravasation, and other symp- toms, a few days after the accident, show the nature of the case, a suture can be of no use whatever, as the adhesive inflamma- tion has already fixed the part in its situ- ation, and the space in which the extrava- sation lies is completely separated from the general cavity of the abdomen by the sur- rounding adhesions. When the bowel does .not protrude, and the opening in it is situated closely behind the wound in the peritoneum, a suture is riot requisite ; for the contents of the gut not passing onward, will be discharged from the outer wound, and not be diffused among the viscera, if care be taken to keep the external wound open. There is no dan- ger of the wounded bowel changing its situation, and becoming distant from the wound in the peritoneum, for the situation which it now occupies is its natural one. Nothing but violent motion or exertions could cause so unfavourable an occurrence., and these should always be avoided. The adhesions, which take place in the course of a day or two, at length render it impos- sible for the bowel to shift its situation. Things, however, are far different when the wounded part of the bowel happens to protrude. Here we have the authority of all writers in sanction of the employment of a suture. No enlargement of the outer wound is requisite to enable the practitioner to adopt such practice ; there is no disturb- ance of the adjacent parts; there is no doubt concerning the actual existence of the injury . no difficulty in immediately finding out its situation. But, though authors are so generally agreed about the propriety of using a suture in the case of a wounded and protruded bowel, they dift’er exceedingly both as to the right object of the method, and the most advantageous mode of sewing the in- jured part ot the intestine. Some have little apprehension of extravasation, advise only one stitch to be made, and use the li- gature chiefly with a view of confining the injured bowel neat* the external wound, so that in the event of an extravasation the eft'used matter may find its way outward. Other writers wish to remove the possibi- lity of extravasation, by applying numerous stitches, and attach little importance to the plan of using the ligature principally for the purpose of keeping the intestine near the superficial wound. When the wound of a bowel is so small that it is closed by the protrusion of the villous coat, the application of a suture must evidently be altogether needless ; and since the ligature would not fail to cause irritation, as an extraneous substance, the employment of it ought unquestionably to be dispensed with. Supposing, however, the breach in the intestine to be small, yef sufficient to let the feces escape, what method ought to be VYOI/NDS. adopted V The following practice seems rational. As Sir Astley Cooper was ope- rating on a strangulnted hernia, at Guy’s hospital, an aperture giving issue to the in- testinal contents was discovered in a portion of the sound bowel, just when the part, was about to be reduced. The operator, inclu- ding the aperture in his forceps, caused. a tine silk ligature to be carried beneath the point of the instrument, firmly tied upon the gut, and the ends cutoff close to the intestine. The part was then replaced, and the patient did well. Mr. Travers, who has related this fact, approves of the plan of cutting away the extremities of the ligature, instead of leaving them hanging out of the external wound. It appears, that, when the first practice is followed, the remnant always makes its way into the intestine, and is discharged with the stools without any in- convenience. But when the long ends are drawn through the outer wound, and left in it, they materially retard the process of heal- ing. (On Injuries of the Intestines, fyc. p. 1 12, 113.) Let us now inquire what ought to be the conduct of a surgeon, should he be called to a patient, whose bowel is divided through Its whole cylinder, and protruded out of the external wound. Various have been the schemes and pro- posals for the treatment of this sort of acci- dent; and since experience has furnished few practitioners with an opportunity of seeing such a case in the human subject, a variety of experiments have been made on animals, in order to determine what treat- ment would be the most successful. Ram- dohr, indeed, is stated by Moebius to have had occasion to try on the human subject a plan, of which a vast deal has been said and written. He cut off a large part of a mor- tified intestine, and joined the two sound ends together, by inserting the upper within the lower one, and fixing them in this posi- tion with a suture, the ligature being also employed to keep them at the same time near the external wound. The patient re- covered, and the feces continued to pass entirely by the rectum in the natural way. (See Halleri Disput. Anat. Vol. 6, Obs. Med. Miscdlan. 18.) About a year after the operation, the patient died, when the anatomical prepara- tion of the parts was sent to Ramdohr by Heister. They were preserved in spirits of wine, and exhibited, according to the latter author, an union of the two ends of the bowel together, and their consolidation ivilh a part of the abdomen. Now it has been questioned by a late writer, whether the union here spoken of ever really happened. When the upper end of the bowel is intro- duced into the lower, the external surface of the former is put in contact with the inner one of the latter; a serous membrane is placed in contact with a mucous one. These heterogeneous structures, he alleges, are not disposed to unite. The mucous membrane, when inflamed, more readily secretes h kind of mucus, which would be an invincible obstacle to adhesion. He thinks it therefore more than probable, that,, in the case related by Heister, the invagi- nation was maintained by the union of the intestine with the corresponding part of the abdominal parietes. Several experiments on living animals have convinced him that this happens, ana that the mucous mem- brane will not unite with the external peri- toneal coat. This impossibility of produ- cing an immediate union between the mu- cous and serous membranes may of course be urged as an objection to Ramdohr’s practice. (Richer and, Nosographie Chir. T. 3, p. 344, 345, Edit. 4.) Another equally strong objection is, that the upper end of the bowel cannot be put into the lower one, unless it be separated from a part of the mesentery. Here the division of the mesenteric arteries may cause a dangerous bleeding. In vain did Boyer tie seven or eight of these vessels : his patient died with an extravasation in the abdomen. ( Riche- rand ’, T 3, p. 343, Edit. 4.) Moebius attempted to repeat Ramdohr’s operation upon a dog; but he could not succeed in insinuating the upper part of tho divided bowel into the lower one, on ac- count of the contraction of the two ends of the intestinal tube, and the smallness of the canal. Moebius, therefore, was obliged to be content with merely bringing the ends of the bowel together with a suture : the ani- mal soon afterward died of an extravasa- tion of the feces. Dr. Smith, of Philadelphia, also tried to repeat Ramdohr’s method, but could not succeed. He divided the intestine of a dog transversely, and having inserted a piece of candle into that portion of the bowel, which was supposed to be uppermost, he endea- voured to introduce the superior within the inferior; but the ends became so inverted, that it was found utterly impossible to suc- ceed. The scheme was therefore given up, and only one stitch made, the ligature being then attached to the external Wound, in the manner advised by Mr. John Bell. The dog died, and on examination there was found a considerable quantity of feces and water in the abdominal cavity. Two more trials were made of Mr. John Beil’s plan, by Dr. Smith, on the intestines of dogs. In both instances the animals died, the intestines being much inflamed, and feces effused in the abdomen. (See Dr. Smith's Thesis.) Mr. Travers likewise tried the same ex- periment. <{ 1 divided the small intestine of a dog, whTch had been for some hours fast- ing, and carried a fine stitch through the everted edges, at the point opposite to their connexion with the mesentery. The gut was then allowed to slip back, and the wound was closed. The animal survived only a few hours. Examination. The pe - ritoneum appeared highly inflamed. Adhe- sions were formed among the neighbouring folds, and lymph was deposited in masses upon the sides of the wounded gut. This presented two large circular orifices. Among 684 WOUNDS. the viscera were found a quantity of bilious fluid, and some extraneous substances, and a worm was depending from one of the apertures. By the artificial connexion of the edges in a single point of their circum- ference, and their natural connexion at the mesentery, they could recede only in the intervals, and here they had receded to the utmost.” In another experiment, Mr. Tra- vers increased the number of points of contact, by placing three single stitches upon a divided intestine, cutting away the threads, and returning the gut. The animal died on the second day. Examination. Similar marks of inflammation presented themselves. The omentum was partially wrapped about the wound ; but one of the spaces between the sutures was uncovered, and from this the intestinal fluids had esca- ped. On cautiously raising the adhering omentum, the remaining stitches came into view. Here again the retraction was con- siderable, and the intervening elliptical aperture proportionally large. On the side, next to the peritoneum, however, the edges were in contact and adhered, so as to unite the sections at an angle. From such experiments, the conclusion drawn by Mr. Travers is, that apposition at a point or points, is, as respects effusion, more disadvantageous than no apposition at all ; for it admits of retraction and prevents contraction, so that each stitch becomes the extremity of an aperture, the area of which is determined by the distance of the stitches. (P. 116, 119.) This gentleman therefore maintains, that the absolute contact of the everted surfaces of a divided intestine, in their entire circumference, is requisite to secure the animal from the danger of abdominal effusion. (P. 121.) The species of suture employed (says Mr. Travers) is of second- ary importance, if it secures this contact. (P. 134.) And among other observations, I find “ wounds amounting to a direct divi- sion of the canal are irreparable, and there- fore invariably fatal.” (P. 133.) These inferences do not appear to me satisfactorily established. We are told, that apposition at a point or points is, as respects effusion, more disadvantageous than no ap- position at all, and that the absolute con- tact of the divided surfaces, in their entire circumference, is requisite to secure the animal from the danger of abdominal effu- sion. The foundation of these unqualified conclusions is five experiments made on dogs, in four of which experiments the di- vided bowel was brought together with one stitch, on Mr. John Bell’s plan, while in another three stitches were made ; and yet, in all these instances, the animals died with the contents of the bowels effused. So far the inferences seem established. Unfortu- nately for their stability, however, Mr. Travers immediately afterward proceeds to relate other experiments, instituted by Sir Astley Cooper, Dr. Thomson, and Dr. Smith, which, though Mr. Travers seems unaware of the fact, tend Piost completelv to overturn the conclusions, which he had been previously making. “ Sir A. Cooper repeated the experiments of Duverger, who had succeeded in uniting by suture, the divided intestine of a dog, in- cluding in it a portion of the trachea of a calf. In place of the uninterrupted suture, three distinct stitches were inserted. On the six- teenth day the animal was killed, and the union was complete.” (P. 123.) Here are two facts, proving diat a wound- ed intestine may be united, though the suture was not such as to maintain the divided sur- faces in contact, in the whole of their cir- cumference. Sir Astley Cooper then made the experi- ment, without including the foreign sub- stance. The animal recovered, being a third fact, tending to prove, that the absolute contact of every point of the ends of the divided bowel is not essential to the cure. (See A. Cooper on Inguinal and Congenital Hernia, Chap. 2.) After dividing the small intestine of a dog. Dr. John Thomson, of Edinburgh, applied five interrupted stitches, at equal intervals, the ends of the ligatures were cut off, and the external wound was closed with a su- ture. This animal did not die of the opera- tion, and when he was afterward killed, it appeared that the threads had made their way into the interior of the intestinal canal. Dr. Thomson repeated this experiment, and did not kill the animal till six weeks after- ward, when the same tendency of ligatures to pass into the bowels, and be thus dischar- ged, was exemplified. These two last cases make five, in proof that the absolute contact of every part of the ends of a divided bowel is not essentia? to prevent effusion, or the cen§equences of the wound from proving fatal ; and several other experiments were made by Dr. Smith, of Philadelphia, who employed four stitches with similar success. As far then as the majority of such facts ought to have weight, we are bound to re- ceive the conclusions of Mr. Travers as in- correct, and unestablished. I am only sur- prised, that Mr. Travers himself, who has cited the particulars of all these last experi- ments, did not perceive, that they struck di- rectly at his own inferences. They are not only irresistible arguments against Mr. Tra- vers’s conclusion, that the union of a divided bowel requires the contact of the cut extre- mities in their entire circumference; but they are a plain denial of another position advanced by this author, viz. that wounds amounting to a direct division of the canal, are irreparable, and, therefore, invariably fatal. With respect to the species of suture be- ing of secondary importance, provided it secure the complete contact of every part of the everted ends of the divided bowel, I regret, that Mr. Travers has omitted to insti- tute experiments, in order to show that any such suture can be practised, and if he has the ingenuity to apply it, whether the result would be for or against the conclusions WOUNDS, which he has formed. The lact of the su- tures always making I heir way into the cavi- ty of the bowel, and being thus got rid of, appears to me highly interesting, since it shows the safety of cutting away the ends instead of leaving them hanging out of the external wound, so as to creale the usual ir- ritation and inconveniences of extraneous substances. It seems that Mr. Benjamin Bell first recommended cutting the ends of the li- gatures away, and reducing the bowel in this state into the abdomen, as, he says, a con- siderable part of the remainder of the liga- ture will fall into the cavity of the gut. ( Sys- tem of Surgery, Vol. 2, p. 128, edit. 7.) We have seen that the experiments of Dr. Thom- son confirm the observation, and those insti- tuted by Mr. Travers, tend to the same con- clusion. According to the latter writer, the follow- ing is the process, by which a divided intes- tine is healed, when sutures are employed. “ It commences with the agglutination of the contiguous mucous surfaces, probably by the exudation of a fluid, similar to that which glues together the sides of a recent flesh wound, when supported in contact. The adhesive inflammation supervenes, and hinds down the everted edges of the peritoneal coat, from the whole circumference of which a layer of coagulable lymph is effused, so as to envelope the wounded bowel. The ac- tion of the longitudinal fibres, being oppo- sed to the artificial connexion, the sections mutually recede, as the sutures loosen by the process of ulcerative absorption. During this time, the lymph deposited becomes or- ganized, by which further retraction is pre- vented, and the original cylinder, with the threads attached to it, is encompassed by the new tunic. “ The gut ulcerates at the points of the ligatures, and these fall into its canal. The fissures left by the ligatures, are gradually healed up; but the opposed villous surfaces, so far as my observation goes, neither ad- here, nor become consolidated by granula- tion, so that the interstice, making the divi- sion internally, is probably never obliterated.” (Travers on Injuries of the Intestines , fyc. p. 12S.) Notwithstanding I have carefully read all the arguments adduced by Mr. Travers in favour of stitching a divided bowel at as many points as possible, I still remain un- convinced of the advantage of such practice, for reasons already suggested. If a case were to present itself to me, in which a bowel, partly cut through, protruded, l should apply only a single suture, made with a small sewing-needle, and a piece of fine silk. If the bowel were completely cut across, I should have no objection to attach its ends together by means of two or three stitches of the same kind. I coincide with Mr. Travers, respecting the advantage of cutting off the ends of the ligature, instead of leaving them in the wound, as I believe he is right, in regard to the little chance there is of the injured intestine receding far from the wound, and if the ends of the ligature && are then of no use in keeping the bowel in this position, they must be objectionable, as extraneous substances. As confirming some of the foregoing ob- servations, I would refer to the valuable wri- tings of Scarpa, and those of Dr. Hennen. The parts of the former, to which I allude, being contained in the last edition of the First Lines of Surgery, need not here be re- peated. u The older practitioners, (says Dr. Hennen,) were very much averse from leav- ing any thing to nature in cases of abdomi- nal injuries, although their universal em- ployment of sutures ought to have convinced them, bow much she could bear with impu- nity; for there can be very little doubt, that their uniform performance of the operation of gastroraphe was at least superfluous, if not positively hurtful. In the course of a very extensive, practice, two cases only have come under my notice, where if was required to a wounded intestine, though frequently it may be needed for injuries to the parietes.” (On Military Surg. ed 2, p 411.) When the protruded intestine is mortified, which must be a very rare occurrence in cases of wounds, the treatment should be the same as (hat of a mortified enterocele. (See Hernia.) As Dr. Hennen observes, in the treatment of wounds of the abdomen, the violence of sypmtom • is to be combated more by gene- ra! means, than by any of the mechanical aids of surgery. The search for extraneous bodies, unless superficially situated, or they can be felt with a probe, is entirely out of the question. “ Enlargement, or contrac- tion of the wound, as the case may require, for returning protruded intestine, securing the intestine itself, and promoting the ad- hesion of the parts, is all that the surgeon must do in the way of operation ; and even in this, the less he interferes the better.” (On Military Surgery, ed. 2 p 401.) The principal indicat ion is to prevent n dangerous degree of inflammation. Hence bleeding and the antiphlogistic treatment are highly indispensable. Let not the sur geon be deterred from such practice by the apparent debility of the patient, hi^ smalt concentrated pulse, and the coldness of bis extremities, symptoms common in acute in- flammation of the bowels, and, in fact, them- selves, indicating the propriety of repeated venesection. Wounds of the small intes- tines are attended with more dangerous symptoms than those of the large ones. AH flatulent, stimulating, and solid food, is to be prohibited. The bowels are to be daily- emptied with glysters, by which means, no matter will be suffered to accumulate in the intestinal canal, so as to creale irritation and distention. When excrementitious matter is discharged from the outer wound, it is highly necessarv to clean and dress the part very frequentl)* Gentle pressure should also be made with the fingers, at the circumference of (ha vvouud, at each time of applying the dress- ings, for the purpose of promoting the es* WOUNDS. &80 cape of any exlravasated matter. For (be same reason, the patient should always lie, if convenient, in a posture that will render the external opening depending. After a day or two, the surgeon need not be afraid of letting the outward wound heal up; for the adhesive inflammation, all around the course of the wound, will now prevent any extravasated matter from becoming dif- fused among the viscera. If the case should ond well, the intestine generally undergoes a diminution in its diameter at the place where the wound was situated. When this contraction is considerable, the patient oc- casionally experiences colic pains at the part, especially after eating such food as tends to produce flatulence. As these pains usually go entirely off after a certain time, and no inconvenience whatsoever remains, the in- testine may possibly regain its wonted capa- city again. A more considerable constric- tion of the above sort has been known to occasion a fatal miserere. Even the intes- tine itself has been known to burst in this situation, after its contents had accumulated behind the contracted part. Patients who have recovered from wounds in the intes- tines, should ever afterward be particularly careful not to swallow any hard substances, or indigestible flatulent food. On this sub- ject the writings of Scarpa are particularly interesting. In some instances, intestinal matter con- tinues to be discharged from the outer wound, either in part, or entirely, so that either a fistula, or an artificial anus, is the consequence. A fistula is more apt to fol- low, when an intestine has been injured by a ball, has been quite cut through, or has mortified. But numerous cases prove, that this is not invariably the consequence, and that a perfect cure has frequency followed each of these occurrences. (See Amis, Arti- ficial.) When an intestine is completely cut through, and the lower portion of the canal lies inaccessibly concealed in the abdomen, writers insist upon the necessity of promoting the formation of an artificial anus. In this particular case, they recommend fixing the extremity of the intestine with a fine suture, to the edges of the outer wound. In order to distinguish the upper end of the intestine from the lower, the proposal is sometimes made to give the patient a little milk, and to observe whether the fluid, after a time, issues from the mouth of the protruded gut. In the mean while fomentations are employed. If the upper end of ihe intestine be in the abdomen, these speculative authors even deem it justifiable, when the accident is quite recent, to dilate the outer wound, search for the hidden continuation of the bowel, and then sew the two ends together. Practical surgeons, I believe, are right in attaching little value to such directions. “ Indeed, (says a modern writer,) the surgi- cal world have long since dismissed their feurs about the intestine falling inwards, and about the difficulties of distinguishing be- i ween the right and the wrong end of it The apprehensions of abdominal effusion? are now all pretty well subdued. The occur rence is extremely rare, and when it does happen, we leave the poor wretch to die in peace, without searching after effused fluids, the nature of which cannot be known, or if known, the information canno‘ in the most remote degree lead to recovery. I have never witnessed a case where any possible good effects could follow the paracentesis; for peritonitis, in its most exquisite form, has always preceded the symptoms which would lead to the performance of that ope- ration.” ( Hennen on Military Surgery, Ed, 2, MU ) In some instances, musket-balls pass into the abdomen, lodge there a considerable time, and are tiien voided through the in- testinal canal ; while, in other examples, they become encysted, and continue lodg- ed (he rest of the patient’s life, without producing much, or, indeed, any inconve- nience. Contusions and other Injuries of the Ab- domen. — A violent contusion of the abdo- men may injure the contained viscera, with- out the occurrence of any external wound. It was in this way, that the liver or gall- bladder was ruptured in the boy mentioned by Mr. Fryer, (Med. Chir. Trans. Vol. 4 ;) and that the vena cava was lacerated in the case which fell under the observation of Richerand, where a cart-wheel passed over child’s belly. (Koso^raphie Chir. T. 3, p. 353.) In other instances, the mischief is done to the intestines ; and still more fre- quently, the viscera, as well as the parietes of the abdomen, have only suffered a more or less forcible contusion. The effects of such violence, are inflammation of the in- jured bowels, and their adhesion to the in- side of the peritoneum. Thus the stomach and intestines, the liver, and the gall-blad- der, w T hen inflamed from a blow upon the front of the belly, contract adhesions to Ihe corresponding portion of the parietes, which has been also bruised, and is itself inflamed. When such inflammations suppurate, (and, according to Richerand, it is their most usu- al course,) on opening the abscess, the pus is found blended with the matter, which the viscera contain or secrete. Thus the alimen- tary matter, and even intestinal worms have been discharged with the pus on opening certain abscesses, which communicated with the cavity of the stomach or bowels ; and bile has been found blended with the mat- ter of abscesses in the right hypochondri- um. When in consequence of a blow upon the anterior part of the belly, the patient expe- riences in the situation of the injury a deeply- seated pain ; wdien a tumour forms, and the symptoms indicate violence done to some of the adjacent viscera ; the inflammation is to be opposed by every possible antiphlogistic means. But when, notwithstanding such treatment, the swelling increases and suppu- rates, the abscess is not to be opened until it is perfectly mature. The inflammatory symp- toms, which preceded its formation, indicate WOUJN’DH. 63 vhat there is an adhesion between the in- jured organ and the parietes of the abdomen. Without this adhesion, opening the abscess would be attended with more risk, because the pus, or other matter, might become ex- travnsated in the cavity of the peritoneum. For the same reason, in the examples of tu- mours, caused by bile in the gall bladder, J. L. Petit recommends deferring the opera- tion of opening them, until the inflammatory symptoms evince, that an adhesion has taken place between the fundus of the gall bladder, and the corresponding point of the parietes of the abdomen. An adhesion of the abdominal viscera to the inner surface of the peritoneum may be induced by other causes, besides the action of contusing bodies. A knife, a fork, a shoemaker's awl, a needle, and other extra- neous substances incapableof passing through- out the alimentary canal, have been known to irritate the stomach, or bowel, and to bring on adhesion of them to the parietes of the abdomen, where a tumour has formed, which, on being opened, has discharged the foreign body. The records of surgery abound in facts of this kind. A fistula suc- ceeds the opening of the abscess ; the ali- mentary matter escapes ; and if the aper- ture admit not of beiug healed by methodi- cal compression, the intestinal canal between the fistula and the anus contracts ; most of the contents of the bowels pass out at the preternatural opening, and the patient falls into a state of marasmus, the more quickly fatal, the nearer the injury of the intestinal canal is to the stomach. A long-continued pressure on the epigas- tric region may cause an adhesion of the stomach to the peritoneum, and suppuration taking place at the part, a fistula, communi- cating with the cavity of that organ, may be formed, and allow the victuals to escape ex- ternally. (See Richer and, Physiologic, T. 1. Chymijication : A osographie Chirurg. T. 3 ,p. 353 — 356, Ed. 4.) I shall conclude, with repeating, that in the generality of injuries of the abdomen from external violence, whether wounds or contusions, the principal danger depends upon inflammation of the peritoneum. In the treatment, therefore, the most necessary thing is to prevent and oppose this perilous affection. Copious and repeated venesec- tion, the application of leeches, mild ape- rient clysters, a low fluid diet, perfect rest, fomentations, and the warm bath, are among the most effectual antiphlogistic remedies, which, in such cases, are entitled to praise and confidence. For information on wounds of the abdo men, see Flajani, Osservazioni, fyc. T. 3. A. Malaval Qucestio, fyc. an tenuium inlesti- norum vuluus letkale ? Paris, 1734. fVcncker , Virginis per viginti septem annos ventriculum perforatum habentis, Hisloria et Sedio, Ar- gent. 1743. Haller, Disp. Chir 6 — 19. Callisen's Systema Chirurgice Hodiernee, T. I, p. 697, fyc. Edit. 1798, Hafnice. Richerand, Nosogr. Chir. T. 3, p. 327, fyc. Edit. 4. Med Chir. Trans. Vof. 4,p. 330. J. Cromp- ton's Case of Rupture of the Stomach and Escape of its Contents, fyc. with Obs. by B. Travers , in Med. and Chir. Trans. Vol. 8, p. 228, fyc. Richter, Anfangsgriinde der IV un - darzneykunst, B. 5, Kap. 1. Discourses on tht Nature and Cure of Wounds, by John Bell , Edit. 3. L. Nahnoni , De Simiiium par- tium humanum corpus consiituteniium rege- nera tiont, Mediolani. 1782. Encyclopidie Methodique, Partie Chir. Art. Abdomen et Intestins. Dr. Smith’s Inaugural Thesis. B. Travers, an Inquiry into the Process of Nature. in repairing Injuries of the Intes- tines, 8 vo. 1812. J. Hunter on Gunshot Wounds. Sir A. Cooper’s work on Inguinal and Conge- nital Hernia, Chap. 2, fol. 1804. Sabatier, Midecine Op&ratoire, T. 1. Petit, Essai sv.r Its Epanchemens, fy Suite de V Essai sur les Epanchemens, in M6m. de I’Acad. de Chir. For information on wounds in general, sec Coes. Magatus, De Rara Medicalione Vul- nerum, seu de Vulneribus raro tractandis , fol. Ven. 1616. A. Read, his Works, containing , 1. Lectures on Tumours and Ulcers. 2. A Treatise of the first Part of Chirurgery, which teacheth the reunilion of the parts of the Body disjointed, arid the methodical doctrine of Wounds, fyc. 2d Edit. 8vo. Loud. 1650. Wer- ner, De Vulneribus absolute et per accident le- thalibus, Regiom. 1650. J. Bohn, De rtnun- ciatione Vulnerum ; seu Vulnemm Lethalium Examen , 12mo. Lips. 1689. P. Ammannus , Praxis Vulnerum lethalium, fyc. 12 mo. Fran - cof. 1690. ./. Colbatch, New Light of Sur- gery, showing a more safe and speedy way of curing Wounds, thati has hitherto been prac- tised, 12 mo. Lond. 1695. Ph. Com. Fabri ♦ civs, Programma quo causae injr^quentice vul- nerum lethalium, pree minus lethiferi sexfab- rica corporis human! anatomica , el situpartium praecipue eruuntur, Ilelmstad. 1753. John Hunter, a Treatise on the Blood, Inf animation, fyc. John Bell’s Principles of Surgery, and his Discourses on Wounds. W. Balfour, Ob- servations on Adhesion , with two Cases, de- monstrative of the Powers of Nature to re- unite parts , which have been totally separated from the animal System, 8 vo. Edinb. 1814. Larrey , M6moires de Chirurgie Militaire, Memoir es et i rix de V Academic Royale de. Chirurgie. Sabatier, Mcdecine Oplraloire. Assalini, Manuale di Chirurgia ; Milano , 1812. Richerand, Nosogr. Chir. Ed. 4. Boyer , Trait 6 des Maladies Chir. T. 1. Delpech , Precis des Maladies Reputtes Chirurgicales , T. 1. Sclimucker , Wahrnehmungen und Chi- rurgische Schriften. Lombard, Instruction Som maire sur VArl des Pansemens, 8ro. Stras- bourg. 1797. Also, Clinique Chirurgicale relative aux plaies, 8vo. Strusb. an. 6. Guth- rie. oi. Gunshot Wounds. 2d Edit. Jones, on Hemorrhage. Schreger, Chirurgische l er- siiche, B 2. p. 260, fyc. 8 vo. Nurnberg. 1818. Thomson's Lectures on Inflammation, 8 vo. 1813; and his Report and Obs. made in the Military Hospitals in Belgium, Sro. 1816. J. Hennen’s Military Surgery, Ed. 2, 8ro. Ed in. 1820; and the various Works cited in the course of this article, and at the conclusion of that on Gunshot Wounds. For information on poisoned wounds, consult F. Re&, Osser* BOUNDS ■tibS vasioni inlorno alle Vipere. Firenze, 1664. M. Charas, Nouvelles Experiences sur la Vipere , 4 to. Paris, 1669. Also, a Reply to Redi's Letter, concerning Vipers. 12 mo. Lond. 1673. Stanford Wolf erstan. Inquiry into the Causes of Diseases in General , fyc. Also, of the Venom of Vipers, 12 mo. Lond. 1692. A. Moureau de Jonn6s Monographic dn Trigono- ciphale. des Antilles ou Grand Vipere Fer-de Lance de la Martinique, Par 8 vo. 1816. A. Vater. et F Gensler, de Antidolo JYovo ad- verms viper arum morsum, prcesentissimo in Anglia hand ita pridem delecto ; Witlemb. 1736. ( Haller , Disp. ad Morb. 6, 693.) J. E. Bertin et J. F. C. Morand, Thesis in here verba , ergo Specijicum Viperce Morsus antido- tum Alkali Volatile, in Haller's Disp. ad Morb. 6,611, Paris. 1 749. Catesby's Hist, of Carolina. Mead on Poisons. Fontana , on the Venom of the Viper. Acrel de Morsura Serpentum, 4 to. Upsal. 1762. Russell , on Indian Serpents Ireland, in Med. Chir. Trans. Vol.2. Sir E. Home, in Phil. Trans. 1810. WRY-NECK. ( Caput Obslipum ; Torti- collis.) An involuntary and fixed inclina- tion of the head towards one of the shoulders ; a disorder not spoken of by the ancients. It should not be confounded with a mere rheumatic tension and stiffness of the neck, nor with the faulty position of the head, arising from deformity of the cer- vical vertebrae. Tulpius, a learned physician at Amster- dam, about the middle of the seventeenth century, has recorded the cure of a boy, twelve years old, who, from his earliest infancy, had had his head drawn down to- wards the left shoulder, by a contraction of the scalenus muscle. Fomentations were applied in vain. The head could not be brought into the right posture, even with the aid of steel collars A consultation was therefore held, in which it was decided to put the boy under the care of Minnius, a surgeon who had performed several opera- tions with success in similar cases. A large eschar was first made with caustic ; and tiie muscle, which drew the htad to one side, was then divided with a knife. Tulpius, who has left a very confused account of the operation, observes that it was performed with great slowness and circumspection, for fear of wounding the carotid artery and jugular vein. However, he offers one good piece of advice, which is, not to make any preliminary application of caustic, as it only causes useless pain, and cannot be of any service. He also recommends the ope- ration not to be done by little and little, at repeated times ; and says, that the surgeon should make a complete division of the muscle at once, with the necessary degree of caution. Job k Meckren also treats of the opera- tion for the cure of a wry-neck. He states, that he had seen it performed on a boy, fourteen years old. The tendon of the sterno-cleido-mastoideus muscle was skill- fully divided with one stroke of a sharp pair of scissors, by a surgeon named Flurianu and as soon as the incision was made, the head resumed its right position. ( Obs . Med. Chir. C. 33.) Mr. S. Sharp believed, that the wry-neck mostly arose from a contrac- tion of the sterno-cleido-mastoideus muscle, which he proposed the division of, when- ever the disorder seemed to proceed from this kind of cause. However, he made an exception of cases, in which the disorder had existed a considerable time, or from in- fancy. He remarks, that, if the cervical vertebrae have grown in a distorted direc- tion, the position of the head cannot be rectified. With these restrictions, the fol- lowing is the operation, which he recom- mends : A transverse incision is to be made through the skin and fat, of a size somewhat more extensive than the breadth of the muscle, and about one third of its length from the clavicle. A probed razor is then to be passed underneath the muscle, and to be drawn out, so as to make the re- quisite division of the part. After the inci- sion has been made, Mr. Sharp recommends the wound to be filled with dry lint, and to be always dressed in a way best calculated to keep the extremities of the muscle from growing together again. For this purpose, he directs the cut ends to be separated from each other as much as possible, with the assistance of a bandage to support the head, duringthe w'hole time of the cure, which, he says, will generally be about a month (On the Operations of Surgery, Chap 35.) According to Mr Sharp’s account, this operation ought to be common. However, if attention be paid to the nature and causes of the disease, and to the differ- ences resulting from whether the disorder be recent, or of long standing ; constant, or periodical ; idiophatic, or sympathetic ; dependent on spasm, or merely on paraly- sis of the antagonist muscles; and, lastly, if it be recollected, that the affection may be produced by other muscles, besides the sterno-cleido mastoideus ; it will appear, that cases, in which the foregoing opera- tion can be judiciously undertaken, are not frequent. With regard to the manner in which Mr, Sharp operated, Mr. B. Bell conceived, that it was attended with hazard of wound- ing the large blood vessels. But, though it seems to me better to use a probe-pointed bistoury and a director, than the kind of razor which Mr. Sharp employed, I do not coincide with Mr. B Bell in thinking, that the latter surgeon’s plan was at all objectionable on the score of danger, in re- spect to wounding the vessels. Some practitioners may even think Mr. B. Bell’s method most likely to injure the large ves- sels; for be advises the operator to cut the muscle from without gradually inward, as deeply as necessary. Perhaps, the most prudent method of operating, is to divide the clavicular portion of the contracted muscle, near the clavicle, and even to cut out a sufficient piece, to re move all chance, of the twe ends uniting WRY-NECK. 689 again, This step would weaken the muscle considerably, and perhaps, might answer every purpose. It could easily be accom- plished, by means of a director, and curved bistoury, after making the requisite division of the skin with a common scalpel. Were this proceeding to produce only partial amendment, the sternal port ion of the mus- cle might afterward be divided. A director should be passed under it, and the division made with a probe-pointed curved knife. Any cause, destroying the equilibrium be- tween the two sterno-cleido-mastoidei mus- cles, will produce a wry-neck. Thus, when one of them is affected with spasm, and acts more forcibly than Uie other, it draws the head towards the shoulder of its own side ; but, when one sterno-cleido-mastoideus is paralytic, while the other retains only its natural power, the balance of action is equally destroyed, and the sound muscle in- clines the head toward the nearest shoulder. Jn paralytic cases, electricity, (Phil. Trans. Vol. 68, p. 97 ; Gilby. in London Med. Journ. Vol. 4, 1790.) blisters, stimulating liniments, the shower bath, seh-bathing, issues, setons, the application of moxa, and attention to the health in general, are the means affording the best chances of relief. Although the wry-neck may occasionally depend on the state of the sterno-cleido- mastoidei muscles, the case is far from being frequent The deformity is much oftener owing to some affection of the integuments. Louis often successfully divided contractions of the skin, which had kept the head drawn to one side for many years, and had been occasioned by burns. Some of these con- tractions, he says, might easily have been mistaken fora part of the sterno-cleido-mas- toideus itself. Mr. Gooch relates a case of wry-neck, which was caused by a contraction of the platysma myoides muscle. The patient was a young gentleman, fourteen years of age, who had always enjoyed very good health in every other respect. For several months, his head had been strongly drawn to one side by a constant contraction of the platys- ma myoides muscle, which was exceedingly rigid, especially about its insertion at the basis of the jaw, and from the angle of the os maxillare inferius to the chin, the skin presented an appearance like that of the cicatrix of a burn. The same side of the face, quite from the point of the chin, Was much shrunk, and distorted by the contrac- tion of the muscle, and the corner of the mouth, in particular, was so drawn to one side and downward, when the patient turn- ed his head, that a vast deal of deformity was the consequence. From the inferior part of the eyebrow, at the internal angle of the eye, to near the top of the head, there was a kind of furrow upon the skin, about half an inch broad, with a shining, polished appearance, like the cicatrix of a wound, and destitute of hair, which had fallen off. From the corner of the eye downwards, there was the same kind of appearance in a less degree. The patient wag subject to re- Vol. IF ' 87 peated attacks of spasms, whicn began at the insertion of the muscle, and terminated at the eye, attended with a great deal of pain. The ear, and also the temporal and frontal muscles, were sometimes affected in a similar manner. The parts, in the course of the insertion of the muscle into the jaw- .bone, were considerably thickened, without being in the least inflamed externally, and when touched, but not stretched, they were little painful. The subjacent muscles did not seem at all affected. It appears from the account given by Mr. Gooch, that in the treatment of this affec- tion, every known means had been tried, by the advice of the most eminent practi- tioners ; but without effect. Mr. Gooch de* termined to try what benefit would be pro- duced by the division of the muscle. He first divided the integuments a little below the jaw, and thus exposed the whole brea. th of the platysma myoides muscle, the fibres of which seemed to be in a state of violent extension, especially when the patient’s head was inclined towards the opposite side Mr. Gooch then divided the muscle com- pletely across by a very careful dissection, until the fascia? of the subjacent muscles were exposed. The patient was then di- rected to turn his head towards the opposite side, and Mr. Gooch had the satisfaction of observing that the palient could perform this motion, without the face and corner of the mouth being affected, as they used pre- viously to be. The wound was treated in the ordinary way, and no particular symp- toms arose. As soon as the inflammation had subsided, the patient was directed fre- quently to move his head about in order to prevent any kind of stiffness which mi tit ensue from the contraction of the muscular fibres, and the inelasticity of the cicatrix. The patient was perfectly relieved by the foregoing operation, and had no return of the painful spasms, to which he had been previously subject. The side of his face, however, never recovered its proper degree of plumpness. ( Chir . Works of B. Gooch , Vol. 2 ,p. 81.) Whenever an attempt is made to cure a wry-neck, by dividing any of the muscles, or merely the integuments, it becomes ne- cessary to take some measures for keeping the head in a proper position, during the treatment of the wound, lest, in conse- quence of the head inclining in the direc- tion in which it was before the operation, the divided parts grow together again, and bring the patient into the same condition, in which he was before any thing had been done. With a view of preventing this unpleasant circumstance, Mr. Sharp recom- mends filling the wound with lint, and ma- king it suppurate. Mr. B. Bell, on the other hand, advises the employment of a proper machine for keeping the head in a due po- sition. Some writers think the use of a bandage quite sufficient for the purpose. When the sterno-cleido-mastoideus is af- fected, perhaps the excision of a small por tion of if would be prudent ZINC. 690 Boyer met with a case of paralysis of the extensor muscles of the head, attended with a constant approximation of the chin to the sternum. The disease resisted every plan of treatment, and an apparatus for support- ing the head was the only thing found of any use. (See Trait# des Mai Chir. T. 7 ,p. 61, 8 vo. Paris , 1821.) Sharp's Treatise on the Operations of Surgery, chap. 35. Blasius, Ohs. Med. Rar. p. 2, No 1. Cure effected hy operation. Mauchart, De Capile Obstipo, Tub . 1737. Chirurgical Worlds of B. Goochs Vol. 2, p. 81. B. Bell's System of Surgery Roonhuysen , Heylcuren, p. 1, No. 22 and 33 successful operation. Encyclopedic M6tho- dique , Partie Chirurgicale T. 2, Art. Torti- collis. Joh. Christ. G.ottfr. Jorg. itber die Verrkriimmungen des MenschlicHen Harpers , und eme rationelle und sichere Heilart der- selbcn ; Leipzig, 1810. Baron Boyer, Trait 6 des Mai. Chir T. 7, p. 48, fyc., 8 vo. Paris, 1821. z. Z INC. The preparations of this metal are of considerable use in surgery. With respect to the sulphate of zinc , it may be said to be generally the best emetic, in cases where it is desirable to empty the sto- mach without the least delay, as in cases of poison, for which purpose, the common dose is 3j. “ As an external application, this salt dissolved in rose-water, in the propor- tion of gr. iss to %j. of rose-water, forms an excellent collyrium in the latter stage of ophthalmia, after the inflammatory action has subsided ; it is a good injection in a si- milar stage of gonorrhoea ; and a lotion in some kinds of superficial inflammations. Oi double strength, this solution is the best ap- plication that can be used in scrofulous tu- mours, after they have suppurated, and the abscess been discharged.” (A. T. Thomson , London Dispensatory, Ed. 2, p. 559.) The unguentum zinci , composed of an ounce of the oxide of zinc, and six ounces of pre- pared lard, is an useful astringent, mildly stimulant application ; and is frequently em- ployed in various cases of cutaneous dis- eases, ringworm, sore nipples, and chronic inflammation of the conjunctiva of the eyelids APPENDIX. HYDROPHOBrA. Our author, after a most laborious research into the annals of surgery, in orderto ascertain the patho- logy of this disease, and without being able to decide upon any of the at present promulgated opinions, is constrained, be- ing in doubt, at length to ask, “ Does the infectious principle of ixibies reside in the salivary secretion , or in the mucus of the trachea and bronchia and immediately adds, “ The common belief is . that, in hy- drophobia , the salivary glands arc consi- derably affected By this b shon n, that, notwithstanding the mystery in which the pathology of this disease is invol- ved, the mind of the inquirer has been led to the site of the salivary organs, to search for a cause which he deleares himself satisfied existed in no other situa- tion. It is for me now to record a com- munication from a most respectable physician at St. Petersburg, Dr. Maro- chetti, handed me by the Honourable S. L. Mitchill, M. D., in the hope that the medical community of this country will exert itself, as frequently as oppor- tunity may offer, either to substantiate the doctrine of the salivary glands being the particular and primary localit y of hy- drophobia ; or disprove the assertion, by an evidence which shall direct the mind to another source. • St. Petersburgh, 17th (29th) Nov. 1821. Sir — I did myself the honour of en- closing you, about a month since, a ma- nuscript copy of a report read October, 1820, to the Medico-Physical Society of Moscow, by Dr. Michel Marochetti, upon hydrophobic virus, and the means of dis- covering its presence and destroying its activity in an infected subject. Appre- hending that my letter may have mis- carried, I trouble you with the duplicate, accompanied by the same memoir in a printed form, which it has received since my first letter. The art of inoculating for small-pox, and thereby mitigating the violence of the disease, having been first known and practised in the East, encourages a hope that the discovery from the same quar- ter, of a mode of curing the incipient symptoms of hydrophobia, by a process in some degree analogous, may be the means of rescuing numbers of victims from encountering death in one of its most horrid forms. Desiring to give a wide circulation to the paper of Dr. Marochetti, in order that our country may have the early be- nefit of his discovery, I have thought I could not address myself better than to the President of the Medical Society of New-York, who will not fail to give his recommendation so far as it may be me- •rited. S have the honour to be, Sir, respect fully*, your obedient servant, HENRY M1DDEL ON. Hon. S. L. Mitchill. Observations on Hydrophobia : contain- ing certain indications for ascertaining the existence of the hydrophobic poison in an individual , and the means of pre- venting its developement by destroying Us germ. In a memorial read before the Medico- Physical Society of Moscoiv, on the 4 ih of October, 1820; by Michel Marochetti, Attending Physician at the Gallitzin Hospital , and member of the said Society. Printed in St. Peters- burgh, at the Press of Public Instruc- tion, 1821. Among the fatal accidents to which man is exposed, the hydrophobia, a ter- rible consequence of the bite of rabid animals, is a disease whose cruelty is ag- gravated by the insufficiency of all the means hitherto employed to save its vic- tims, and by the acknowledgment of all practical men, that there is no specific against the hydrophobic virus, after ab- sorption has taken place, and the symp- toms have appeared. I shall not under- take a refutation of this truth. I shall only say, that, with a knowledge of the cause, it is possible, by means of help duly- afforded, to prevent the mischief, and consequently to save from certain death, those persons who, before the discovery which I have the honour to announce, had no chance of safety. Hitherto, the professors of the healing art have been ignorant of the true seat of the disease. A crowd of remedies have been administered ; some because they had doubtlessly been employed with suc- cess in' cases where there was no hydro- hobia, and others for the purposes of enevolenee and prevention. But a very APPENDIX important point in medicine, and one that has been sought in vain, is.the cause of this malady. Its effects are, unfortu- nately, but too well known. I shall there- fore, on this occasion, endeavour to state, 1st, the knowledge 1 have derived from observation ; 2d, the origin of the dis- covery ; and 3d, the different patholo- logical occurrences I have been able to collect, with my own remarks upon them. Having spent almost eight years of my life in the southern governments of Rus- sia, where there is a great number of dogs, some of them often run mad, and produce frequent accidents. Repeatedly I have endured the distress of beholding the deaths of these victims. 1 necessa- rily made inquiries concerning hydro- phobia, and tried all the known methods of treating it. Confined to a village in the midst of the wretched creatures, some of whom had been bitten by mad dogs, and others by mad wolves, nobody possessed better opportunities than my- self to follow and to watch the course and progress of this horrible disorder. I now state the conclusions I have drawn from the most scri/pulous atten- tion to hydrophobia. In the. first place, I am convinced by experience, that if several persons are bitten in succession by a rabid animal, the first bitten exhibits in the develope- rnent of the disease, more serious and violent symptoms than the second, this more than the third, and so on ; the poi- son acting always in an inverse ratio to the numbers, in such a manner that the eighteenth or twentieth person may be considered out of danger. Such a case sometimes happens. Secondly, the hydrophobic virus does not constantly reside in tile mouth of the mad animal. — It gathers there only at the end of a certain time. The bite, in this interval, is not to be considered as venomous. Here is another case in which the rabies is not communicated. Thirdly, the hydrophobic virus does not lose, like the pestilential miasma , , any of its intensity in being communicated from one body to another — but it acts with more or iess violence in proportion to its quantity. Unfortunately, the effect is not the less fatal, by reason of its quicker or slower operation. Fourthly, it is evident that this virus does not continue in the wounds ; but is conveyed in its full force to a part of the body presently to be described. In this part, it instantly acts as a most powerful astringent, and, by accumulation, inflames and shuts the passages, by which nature endeavours to expel it from the animal economy. Fifthly, there is one, and only one way, to prevent the developement of hydro- phobia in a person who is threatened with it. I declare boldly, and experience will bear me out in the assertion, that this is to evacuate the hydrophobic virus when itappears. Where does this reside ? and how can it be evacuated ? Sixthly, the sub-lingual glands are two in number, one on each side, under the tongue, between the genio-glossi muscles, the lower jaw, and the inner membrane of the mouth, which immediately covers them. From these glands proceed two or three secretory ducts, which open in- to the ducts of the sub maxillary glands, and those latter open one on the one side, and the* other on the other side of the frajnum of the tongue — it is precisely to the extremities of these ducts, that the hydrophobic virus is conveyed after a bite indicted by a rabid animal, and there it is temporarily detained, forming, at the two spots just described, one or two small tumours of unequal size. By touching, which may be done with a probe, it is found that there is contained a fluctua- ting humour, which is, as absorption proves, the hydrophobic poison itself. It is there that nature delivers to us her enemy, it is from this hold that the sur- geon ought to expel him. Seventhly, the time cannot be exactly defined at which these small tumours will show themselves. If the virus is not evacuated in twenty- four hours it disap- pears by re-absorption . Then no trace is left of its pre-existence. There takes place a double metastasis towards the brain. The most frightful symptoms of hydrophobia commence, and the patient sinks under one of its paroxysms. — On opening the body, nothing remarkable is observed ; pathological anatomy, after all its explorations, has not discovered any indication capable of fixing the atten- tion of physicians, and of rendering an explanation of the causes, because they did not understand the re-absorption of this virus. Eighthly, the first thing to be observed when a person believes he has been bit- ten by a mad animal, is the lower side of the tongue, which ought to be examined for six weeks, once, or even twice a daj r , for more perfect precaution. If at the end of this term there is no appearance of the small swellings already described, we may rest assured that the individual is not to be infected with hydrophobic virus, During these examinations, if the tumours appear, they must be instantly cauterized , or, what is better, opened with a small, sharp lancet. This operation is performed by raising the tongue with one hand, covered with a suitable cloth, to- wards the palate, and somewhat side ways, to the end that the small button® or tumours may be easily touched. For greater convenience the tongue ought to be supported by an assistant: so that APPENDIX. 093 There uiay be made as many longitudinal eyewitness. Leave was obtained from incisions as there are lumps. From these the master of the village; and my per - latter there will proceed some drops of mission w as additionally granted, that a sanious lymph, somewhat greenish , the peasant should take charge of the which, the patient operated upon, will patients. I however imposed two condi • spit out. As soon as the operation is tions; the first of which was, that I over, the patient must wash his mouth should be present at every thing he did ; with a strong decoction of the tops and and the second, that to be sure that the dog flowers of the Genista lateo-iindoria , that had bitten them was really mad. and (Dya’s Broom.) It is almost superfluous hydrophobic, I should practise upon one to observe, that this decoction must be of the patients in my own way. I se- prepared in advance, for it must be regu- lected from among them a girl, six years larly taken during the six weeks that the old, whom 1 subjected to medical treat- patient is under examination, as a com- ment. The others began to take the de- mon drink. The dose is a pound and a coction of the genista lateodindoria , half per day, in decoction ; or four which the peasant prepared in my pre- drachms a day in pow der, in doses of one sence. drachm each. The prescriber, however, As I passed the greater part of my will always take into consideration the time near these unfortunate persons, 1 age and constitution of the patient. administered my own remedies for the Ninthly, 1 observe that the operation girl I had taken for my own patient. I which consists, in opening the small tu- had engaged a surgeon, with orders not mours, has the great advantage of being to let the peasant do any thing in ray so simple, and so easy to execute, that absence. This plain man began by exa- not only professional men, but every in- mining the tongue of each individual,, dividual who has seen it performed two one after the other, on its low ? er part, or or three times, can perform it himself, under side, every morning and evening. This is very important for the small As the tumours appeared, he showed towns and villages, where, as yet, there them to me; and he opened them, and are no settled and established surgeons, cauterized them with a sort of large I offer myself, on the occurrence of the needle, heated red hot in the candle,, first accident of this kind, to perform the After the operation, he caused them to operation in the presence of any person rinse their mouths with the same decoc- whom the government may be pleased tion which has been mentioned for inter- to appoint. nal use. I inhabited the Ukraine, during 1813, The girl of six years old, whose trpat- in the capacity of physician to his excel- ment bad been continued w ith the great- lency the count Morzezensky. In one. est care, and conformably to the rules of of his villages, called Kijawka, during an established, practice, became the victim evening of the autumn, at the hour when of the experiment ! for, on the morning the peasants return home from their la- of the seventh day after the bite, she was bour, a huge hydrophobic dog of a neigh- suddenly seized with symptoms of hy- houring village, bit fifteen persons of dif- drophobia, and at the end of eight hours ferent ages and sexes. As 1 lived at the expired in my presence, during a parox- distance of five versts, 1 received no intel- ysm of the most frightful symptoms. Iigence until the next morning Proceed- Of the fourteen remaining persons, ing then with all possible speed to the twelve underwent the opt ration of open- place, 1 procured for these unfortunate ing their tumours, and w ere saved. The persons a house, spacious enough to con- two others, w ho had been bitten last, had tain them all, and I placed near them at- no tumours. These fourteen persons, teridants to .nurse and attend them. after hav ing for six weeks made use of While these arrangements were ma- the decoction of Genista , were dischar- king, a deputation of old men waited up- ged Vured. on me, praying that the bitten persons Having remained there more than might be treated by a Peasant of the three years after this occurrence, 1 saw, neighbourhood, w ho had for a number of a number of times, all the individ jals, years made a business of attending such and can attest that their recovery was cases, and with constant success. They complete. all assured me they would bear w itness l state more facts. Being in Podolia in favour of this man, who. according to during 1818, 1 resided in a small tows their declaration, had already served called Meskowka, within the district of several hundred persons in that govern- Olgapal. In the month of February, ment.' twenty six persons, partly Christians and I had previously heard of this man. I partly Jews, of different ages and sexes, was desirous of satisfying myself as to were bitten by a hydrophobic dog. This the efficacy of a means so very important dog made incursions into the town, and to humanity, and of which I had wished having bitten all the persons he met, had to have an opportunity to become an disappeared. The inhabitants, however. (.94 APPENDIX. rallied ; and in their search for him, in the place of his usual retreat, found him dead near a heap of wheat. Though I took great pains to ascertain the successive order of the bites, I was unable to determine the exact series in these twenty- x individuals. So con. durable a number of the bitten and calamitous beings could not be ac- commodated in any house that could he procured. I was therefore obliged to separate them into three divisions ; and send each division to a distinct house. I attached to the first division, nine men; to the second, eleven women ; and to the third, six children. Iri each of the houses I stationed a Hebrew surgeon, to prepare the decoction of the Genista lateo -tinctoria, to administer it to them regularly, and to report to me every thing that happened. The result was, that, in the first divi- sion, five persons had swellings under the tongue ; in the second, all had them ; and in the third, only three of the child- ren. Among these individuals, they who had the deepest and most numerous wounds, experienced the tumours on the third day. The rest on the fifth, seventh, and ninth days. In one woman, these sub lingual swellings did not manifest themselves until the twenty- first day after the bite. This woman had received a slight bite in the right leg. The seven persons who had no tu- mours nevertheless drank the decoction for six weeks, and were then set at liberty with the. res # t, excepting those whose wounds were* not healed. They remain- ed in charge until their entire restoration to health. I have employed, as an excel- lent detergent, the residue of the decoc- tion of the herb Genista, as an applica- tion to the wounds, in the form of a poul- tice. It is not uhfrequently necessary, to give a gentle purgative, once a week, or at least a simple clyster prepared from a decoction of the marsh-mallows of the shops, in which a small quantity of Aslrakan salt is dissolved. By either of these means, costiveness is prevented. There is a matter which merits the greatest attention This is t he succession of forerunning symptoms, observable during the formation of the small pus- tules, whose discovery is the offspring of a most lucky observation. Towards that stage, the pupil of the eye is dilated and fixed ; the look is sad ; uneasiness is complained of; and there is a small pain in the head. These are the only symp- toms I have been able to detect. The simple and easy method of treating per- sons threatened with hydrophobia, is that which has been practised upon about forty individuals with complete success. The little girl, who fell a sacrifice to my experiment, affords a piece of evidence quite as strong. Henceforward a regi- on can be adopted, of which I will war rant the salutary result. Byway of conclusion, I remark, that at different times and places, 1 have treated six persons in the same manner ; among others, a peasant who had been bitten by a mad wolf, as he was going from one village to another. His cries brought other men, who assisted iri killing the ferocious beast, who had been already marked as hydrophobic. The only dif- ference between this and the radical cure, was, that this man, among other wounds, had been bitten on the forepart of the ankle; and that the tendons and liga- ments were so lacerated, that all the sur- gical means which were applied, could not prevent a great deformity of the foot. He was confined to hi§ bed for two months. After the disclosures I have made con- cerning the hydrophobic virus, 1 consider the disease as a local evil , of which it is possible to prevent the consequences, by a seasonable removal of the morbific matter. For after the reabsorption has been made, there are no means of arrest- ing its terrific effects. I think it may be thence concluded, that the known symp- toms of hydrophobia, such as constriction of the breast, violent pain in the head, dilatation of the pupil, occasional palsy of the tongue, convulsions, dread of liquids, all nervous symptoms, are produced by the reabsorption of the hydrophobic poi- son. The nerves from the fifth pair, those which go to the tongue, the inter- costal and corvical nerves, furnish direct evidence of the manner in which the \ irus exerts its deleterious action through the medium of the nerves leading from the sublingual and submaxillary glands. Without taking into consideration the complicated distribution of these nerves, their connexions and sympathies, 1 en- tertain the hope, that Physiology will, one day, give us more satisfactory details on this subject. It only remains for me, gentlemen, to state my sole and particu- lar desire for the publication of a me- moir, useful to humanity, and the chief object of my researches and of my exer- tions. Accept, respectable president, and members, who have had the goodness to receive me as a colleague and fellow- labourer, the observations which I offer you, in the most philanthropic spirit ; add thereto your own intelligence, and aid me with your practical experience. I shall be overjoyed if I should be happy enough to limit the disasters caused by hydro- phobia. ( Signed) M A HOC H ETTf APPENDIX. Since the receipt of the foregoing, the teeth in it. Tn the evening f gave him Doctor has had forwarded to him a some more milk and water, and mutton communication, which, when read, will be broth, which he took freely and went to found in affinity with the preceding Remarks on Hydrophobia , more particu- larly as it occurs in Dogs ; in « letter from a gentleman of observation and exverience in New- Jersey* dated March 15, 1822. Sir— 1 lately read with much plea- sure, in the New-York Spectator oi the 1st instant, Mr. Middleton’s letter to you accompanying Dr. Marochetti’s very interesting report on the symptoms and cures of hydrophobia. As I consider it the duty of every member of the human race, to commu- nicate any thing that may in any way tend to elucidate or corroborate tiiis wonderful discovery, (the greatest th;*t has yet been made in medical science,! 1 beg leave to submit to your considera- tion two cases, which within these eighteen months have fallen within my personal knowledge and information, and may be depended on. On the morning of the eighteenth of December, 1820, while living in Canada, a favourite dog, belonging to me, of the Setter breed, showed what 1 imagined to be symptoms of madness, on which 1 immediately directed my servant to tie him up in an out-house, and to give him some salt and water, as he appeared from scratching his neck and throat until it absolutely bled , to have something sticking in it ; this made him in a short time throw up a quantity of yellow frothy matter, and seemed to relieve him very much, so that at 12 o’clock he ap- peared free from every species of com- plaint. Soon after, the servant gave him some water, which he lapped freely, and immediately threw up a large quantity of the same yellow frothy matter, some of it in large lumps. From these symp- toms, l was induced to think .that he had swallowed some poisonous substance, on which account I gave him some milk and water and fat mutton broth, which lie took freely, and appeared as if sensi- ble of the attention paid him, and as usual wagged his tail, and readily obeyed every order I gave him. Next day his appearance was more unfavourable : his eyes appeared glazed and heavy, his tail drooped, his stomach and bowels were contracted, his back raised in a circular form, and his neck raw from continual scratching. At this time ! had him and the barrow in which he lay removed to a warmer place, which I did witiiout any difficulty, as he knew and obeyed me as usual; yet, soon. after, when I held out my stick towards him, he laid hold, and left the marks of his rest. Ahout midnight 1 was awakened by his incessant and apparently painful barking, which he continued without in- termission until daylight, when he exhi- bited what appeared to me such un- doubted signs of violent madness, that f was under the painful necessity of shoot- ing him. My servant then told me, that the day I desired him to be tied up, he made a snap at his thigh, and gave it a pinch, but having on thick pantaloons,, and drawers, he did not break the skin, and no bad consequences have ensued from it. When staying last August with my friend, Mr. Grant, at Montreal, I happen- . < d to mention all these circumstances to him, when he, pointing to a favourite dog, lying at his feet, told me, that about two years ago he was in so similar a situation, that he left orders with his servant to shoot him, and as he could not do it himself, or be in the way when it was done, he went into the country for some h'*urs. On his return home, the first question he asked was, ‘ l have you disposed of the dog ?” to which, to his great surprise , the servant answered, “ No, sir, l could not find in my heart to kill the poor dumb brute, and as he seemed by his violent scratching to have something in his throat, or mouth, that caused his illness, I got a friend to assist me, who held him down while I opened his mouth for the purpose of examining it, and his throat, when under his tongue ,, I observed a large Blob or Tumour , which I opened with a penknife, and out of it came a great deal of nasty matter, which the dog threw out of his mouth, imme- diately leaped up, frisked about the room as if sensible of the cure that had been effected on him, and he is now as well as ever he was.” Mr. Grant could hardly believe the story ; but the entrance of the dog into the room, in his usual man- ner, to his great joy, confirmed the truth of it. On Mr. G’s relating these circum- stances to me, I mentioned to him, that; I thought the matter of so great conse • quence, that he ought to draw up a state - ment, and communicate it to some medi - cal friend, as it might, perhaps, be the means of finding out a cure for the dis- temper in dogs, which I then thought it was, though was convinced, from Dr. M.’s report, that it was the real hydro- phobia. As I soon after left, that country, 1 do not know whether or not Mr. G. follow- ed my advice ; but in case he has not, I now give you all the circumstances of both cases, well convinced that they can- & APPENfo/X €96 not be placed in better hands; leaving you at liberty to make such use as you may think proper of this information. As Dr. M. mentions having the hands properly covered when examining the mouths of patients, I would beg leave to suggest your publishing what material you deem a proper and necessary cover- ing for the hand ; with which, and a lan- cet, at least one person in each village, or large family, ought, in case of accidents , to be provided, as there are many parts of this extensive country, where medical aid cannot be procured, or the patient unable to pay the expense of the long attendance necessary. And I would also beg leave to suggest the propriety of having this report of Dr. M.’s promulga- ted throughout the country in general, through the medium of newspapers or cheap pamphlets, with the addition of such remarks as you may think proper or necessary to make to it. When 1 was a boy, at school in the North of England, 1 learnt to worm dogs, which, it was said , did not prevent their going mad ; but in case they were infect- ed, occasioned a relaxation or paralysis in the lower jaw, which disabled them from biting any thing, and under that idea, t afterward wormed a number of dogs, but cannot, at this distant period, say what were the consequences or effects of it ; but as the custom was ge- neral, there must have been something in it, and perhaps might have proceeded from the idea that the tongue was some- how afflicted. That the saliva of a mad dog will not communicate the disease, unless carried into the circulation through a wound in the skin, I am perfectly con- vinced, as a lady, a friend of mine, had her face licked all over by a favourite gray hound, which had been tied up on account of being supposed to be infected, but got loose, and immediately after be- ing again tied up, got loose a second time, and ran off, and, before he was killed, bit a number of dogs and cattle, all of which went mad, yet the lady never felt any bad consequences from it. With real esteem, I have the honour to be, Sir, your most obedient, Humble Servant, W. ARMSTRONG. S. L. Mitchill, M. D. March 26, 1822. LITHOTOMY. What I have to say at present upon this article, is founded upon two lately-discovered anatomical facts, which, in my opinion, will become of the first consideration in regulating the operation of lithotomy. The first of them has reference to the particular ex- tent, thickness, and connexion of the triangular ligament of the urethra : and the second to the pelvic partition, or that extension of the fascia iliaca, which passes over the brim of the pelvis to be- come attached to the side of the urinary bladder, and called ileo-vescial-fascia. “ The triangular ligament of the urethra is stretched across the arch, between the rami of the pubes at the anterior edges of these bones. It is connected above, to the middle of the lower edge of the pubic ligament, by which a space is left on each side, for the passage of the internal pu- pendal arteries to the penis. This ligament is about an inch and a half in depth, having its lower edge semi- lunated, and formed into two arches, both sprung from a central projecting portion of the ligament, which will be afterward mentioned as the centre of union of the muscles of the perineum. These arches are concave facing the coccyx, and go towards the tuberosities of the ischia, by processes firmly attached to the inner edge of the bone, and that terminate by being incorporated with the anterior sa~ cro-sciatic ligaments. This branch of the triangular ligament, moreover, assists the sacro-sciatic on each side, in sending up, within the pelvis, the aponeurosis to the obturator in-ternus muscle. The central projecting point, at the lower edge of the triangular ligament, is kept in its place, in giving form to these arches, by the action of the sphincter ani, and transversales perinei muscles. At about the middle of the triangular ligament is a hole, for the urethra, in its passage from the bulb. The triangular ligament is composed of two very distinct lamina;, which are naturally separated at some distance from each other, in consequence of having between them, the glandulse antepros- tatae, or Cowper’s glands.” — Surg. Anal. By this description, I wish it to be un- derstood, that the triangular ligament of the urethra is closing the outlet of the pelvis for a great extent under the arch of the pubis ; and that, at its upper part, it is full half an inch thick, getting gra- dually thinner towards its arched edge, at its under part. Now, in almost every book which con- tains directions for the operation of lithotomy, we are told to “ cut through the common integuments by the side of the rapha of the perineum, against the groove of the staff, which is to be the fir^t incision ; thpn to divide the transversales perinei muscles, which is the second incision; and after this, to feel for the groove of the staff, in the membranous part of the urethra, to cut upon it, and to introduce the beak of the instrument, that is to divide the prostate gland. Hence we find surgeons getting into the bulb of the urethra in- APPENDIX stead oft Up membranous part ; from their attention not having been directed to the presence of the thick triangular ligament. After this, by carrying the beak of their instrument on, they cut the bladder and prostate, and prepare to introduce the forceps for the extraction of the stone, without having made sufficient room for its exit. The bare hint at this circum- stance. will sufficiently account for the pulling and twisting we every da)’ see and hear tell of, during the effort to extract even very small stones by the lateral ope- ration. [ have seen a patient, under such circumstances, sent from the operating table of a large hospital, who died, soon after two hours had been spent in vain efforts to extract not a very large stone, from the urinary bladder. The French surgeons, from having often met with these difficulties, choose at length to dignify the accident by a particular epithet ; not however for the purpose of guarding against it, hut that the world might know they had in- vented a new operation for lithotomy, which they called 1’operation par deux temps : that is, wherein’ the patient, found exhausted by the laborious efforts to extract the stone by the forceps, at the time of the operation, was put to bed, in order to recruit for another trial the following day. 1? operation par deux temps ! The Pelvic Partition. I believe nine out of ten of the cases of death after lithotomy, are to be attributed to perito- neal inflammation, caused by extrava- sated urine retained in some quantity against the under surface of the perito- neum, as it passes from the bladder to the rectum and side of the pelvis. 1 have taken some pains, in the first part of a System of Surgical Anatomy, published this year, to describe the par- ticular connexions of the iliac fascia with the side of the urinary bladder, and to show that a complete septum is formed by this membrane at each side, which is impenetrable by any aqueous fluid ; and by its peculiar attachments, a pit exists at the side of the back part of the bladder, which is bounded below by this fascia, and above and behind by the peri- toneum, as it goes from the bladder to the side of the pelvis. That this pit is likely to be filled with urine, during the incision into the bladder in the operation for stone : and that, when urine is here placed, it has no possible way of escape but by absorption. When urine is in this situation, therefore, it is in constant con- tact with a considerable extent of sur- face of peritoneum; and that, under such circumstances, it is equal to produce ery- sipelatous inflammation of the mem- brane, no one will deny. .1 think it can be demonstrated by fair Voi, If '08 induction, that, from the time of Celsus to the present day, the different opera- tions of lithotomy were successful in pro- portion as this pelvic partition remained uncut. The fatality attending Mr. Chc- selden’s first operation, is to he ascribed to the urinal infiltration, consequent upon the manner in which he divided the blad- der. He cut upwards, and necessarily wounded this partition. We are permit- ted to draw this inference, especially as Mr. Cheselden has not accounted for such events in any other way. The high operation has been laid aside from being so often unsuccessful ; and, in all the descriptions given of that perform- ance, we are left in the dark as to the cause ; being only presented with ac- counts of its comparative ill success. The operation by the apparatus major, I have no doubt, was instituted in its day from a consciousness that something was cut in other operations, that ought not to be cut. Hence the method by dilatation was thought more adviseable. [Surg. Anat. Pari /.] The result of my observations upon the structure of the parts within the pelvis, in reference to the division of the bladder and prostate in the operation of lithotomy, is this ; that there is a line for this inci- sion, which, when observed, the prostate gland can be completely divided, and the neck of the bladder beyond it, for the ex- tent of two inches, with all safety to the patient, and without opening the pelvic partition, or wounding the peritoneum or vesicula seminalis ; which line w ill he obtained by observing the following rule. The patient is to be placed on the table in the usual manner, tied hands and feet, and in that exact position in which he is ordinarily placed for the operation. Then let the knife, having entered the groove of the staff', be carried into the bladder, and the bladder and prostate divided, while the instrument is held in a line with the ho- rizontal table on which the patient lies, that will give an angle of forty-five de- grees. NEEDLE, surgeons’. Every prac- titioner must have felt, even at the ends of his fingers, the inconvenience and diffi culty attending the introduction through the skin of Ihe common curved needle. The young student is almost sure to prick his fingers, in his first attempts at sew’ing up the dead body; although a large needle is then generally made use of. And in the living subject, when bringing arts together by suture, as in case of arelip, it is not always easy to intro- duce the common needle in the course we wish it, or do it at all, in any thing like a graceful manner. The needle is small, rolls between the fingers, and has its point coming out sometimes at a dart at which we feast expect if. APPEND 1 &. 'SJfr Dr. Miller, of Franklin, Massachu- setts, has contrived a delicate instrument, which I think in every instance will be more efficient than the ordinary needle. It is a curved needle, with an eye about the eighth of an inch from its point, fixed into a straight handle, by which full power is had over the instrument. It is first introduced through both lips of in- tegument, and then armed with silken ligature, when the thread takes the place of the needle as the latter is withdrawn. OSTEO SARCOMA The following is an account of three cases in which ex- tensive portions of the lower jaw were taken away for the removal of this dis- ease ; after previously tying the carotid artery, in each individual, by Professor Valentine Mott. Two of these cases were of successful issue, but the third was lost; from circumstances, however, which could not be fairly referred to the opera- tion. On the 12th Nov. 1821, being asked by Dr. Mott to see a patient of his with a curious disease on the right side of the lower jaw, 1 was shown an interesting young woman, by name Catharine Bucklew, of about 17 years of age, of healthy appearance, good constitution, and who gave of herself the following account. She stated that at about two years pre- vious, a swelling commenced behind the last molar tooth, attended with acute pain about the angle of the jaw, that con- tinued for three weeks ; at which time the inflammation left her, without any evi- dent resolution. During this attack there was no inflammation of the integument, nor could any pus be discovered, either on the cheek or about the bone within the mouth. That some domestic appli- cations were made use of to the cheek, hut the swelling remained, assuming the appearance of smooth and hard bone. That, at about twelve months after its commencement, she applied to a physi- cian in New- Jersey, (it being her resi- dence,) who advised blisters to the cheek, with the topical application of caustic to the tumour, together with a general anti- phlogistic constitutional treatment: and that this was persisted in for two months without any benefit. Soon after this she came to the city, and put herself under the care of Dr. Mott, in the New-York Hospital, when the tumour had extended from the root f the coronoid process to the second bieuspis tooth, being elevated nearly an inch above the level of the teeth, and spreading considerably wider than the alveolar processes. Its appearance was smooth, and to the touch somewhat elas- tic, though firm. Dr. Mott made an in- cision on each side the alveolar margin, with a scalpel, by which he was enabled pretty readily to remove the tumour to a level with the jaw bone. The tumour, upon examination after removal, was found to contain many cartilaginous and osseous spiculae ; and in its substance one of the molar teeth was imbedded, in a perfectly sound state. About three months after this a small sprout, which had grown rapidly, was taken off ; she upon this removed to the country, where she remained in a very comfortable state for several months. At the time I saw her, she further stated, that the first molar tooth came away early in the disease ; that the se- cond soon followed; after which, three or four of the other teeth at that side of the jaw ; and that previously to this dis - ease, she had never a decayed tooth : and further, that no fluctuation was to be felt at any time in the tumour ; had no constitutional symptoms as the ef- fects of this disease, nor any inordinate headach on that side. The lymphatic glands of the neck were, however, swol- len during the continuance of the inflam- mation, in the early period of the disease, but disappeared when the pain subsided. When 1 saw her, at the date mention- ed, the tumour had the same firm and slightly elastic feel, which was said to characterize it in its early stage, and in- volved all the right side of the inferior maxillary bone. Projecting outwards, it formed a great convexity of the cheek ; upwards it was divided into two por- tions by a furrow made by the pressure of the teeth of the upper jaw ; this was attended with a constant abrasion of sur- face and discharge, which, though offen- sive, did not appear to be acrid or irrita- ting : downwards, it was nearly in con- tact with the thyroid cartilage ; and in- wards, it extended beyond the middle line of the mouth, pushing the tongue and uvula much to the left side. The tumour, at the back part of the mouth, had encroached so much upon the passage leading to the fauces, and the pressure of the lower part on the pharynx was so considerable, that deglu- tition became difficult ; and from the great inconvenience attending mastica- tion, she had been compelled for some time to subsist upon liquid aliment. Her speech was much interfered with, in con- sequence of the displacement of the tongue ; but she had no pain in any part of the tumour. Under all these circumstances, she was very desirous to be made acquainted if an operation could not be performed, which might extend to her some chance of life; observing, that if she continued in the present state much longer, she would soon be unable to swallow anr APPENDIX. tiling, judging from the vapid growth that the tumour had shown for the few weeks previous ; and fully aware of the danger- ous nature of the novel operation her ease would reouire, she expressed herself determin* a to submit to it, and hazard the consequences. The uncertain result of the operation was fully explained to her by Dr. Mott, and moreover that she might die under its performance ; but that it was believed both practicable and proper. After preparing the sj'stem for about a Week, with a light diet and a few doses of neutral salts, the operation was com- menced on the morning of the 17th. As it was thought prudent to begin by pla- cing a ligature on the common carotid, this vessel was sought for at the middle of the neck, and one ligature placed around it. Very little blood was lost, and only one subcutaneous branch at the lower end of the wound required tying. Although she submitted to this part of the operation with firmness, yet imme- diately afterward she became pale and almost pulseless, with the presentiment that she should die if the operation of extracting the tumour was persisted in. In this her state of mental perturbation, it was resolved not to proceed ; she was therefore put to bed. After she recovered a little, she was apprized that what had been done, was only preparatory to the most important part of the operation ; and that that would prove of little or no benefit to her if it was not further proceeded in. She was then urged to give the thing full con- sideration, and, if possible, to make up her mind to submit to the performance of the remaining part, which on no ac- count should be deferred longer than the following day. 13 tk, 7 A. M. — Found her this morn- ing much composed, having slept well, and free from fever. Upon putting the question, would she submit to the rest of the operation ? she answered, with much decision, that she was determined to un- dergo it. She was, therefore, being cheerful and resolute, at ten o’clock pla- ced again upon the table, when Dr. Mott proceeded with the operation in the fol- lowing manner. Feeling for the condyloid process, the incision was begun upon it opposite the lobe of the ear, and carried downwards opposite the ear, over the angle of the 'aw, in a semicircular direction along the ower part of the tumour as it rested upon the thyroid cartilage, ending at about half an inch beyond the angle of the mouth, upon the chin. After this the se- cond incisor tooth of the right side was ex- tracted, which was from a sound part of the bone ; and upon further separating the soft parts from tire side of the jaw near tire chin, a narrow saw, similar to a key-hole saw, was introduced into the mouth from the wound, by which was divided the jaw-bone in a perpendicular direction, commencing where the incisor tooth had been extracted. The lower part of the tumour was then laid bare by cutting through the mylo-hyoid muscle ; when the flap of the cheek was carefully separated and turned up over the eye. This exposed fully to view the whole ex- tent of the tumour, as it rose towards the os make. Now, after the integuments were cautiously dissected from the paro- tid gland, the masseter muscle was detach- ed at its insertion, until the edge of this gland ; then separating a few more fibres of the muscle under the gland, the paro- tid was readily raised without injury. The maxilla was next laid bare for some way above its angle, where it was seen sound and in a healthy state. To facili- tate the sawing of the bone in this second situation, it was necessary to make a fur- ther incision through integument for about an inch close to the lobe of the ear, and over against the mastoid muscle. Then with a fine saw made for the pur- pose, smaller and more convex than Hey’s, the bone was divided obliquely downward and backward, at a part about midway between the angle and condy- loid process. This part of the sawing was necessarily performed with much caution, to avoid wounding the great ves- sels, and the inferior maxillary nerve. After the bone was sawed through, the action of the temporal muscle separated the coronoid from the eondyloid process, and drew it up under the zygomatic arch. An elevator was now introduced, where the bone was divided at the chin, by which the whole diseased mass was rais- ed ; and, with a scalpel passed into the mouth, the tumour was separated from the side of the tongue, as far back as the posterior fauces. The tumour could now be turned against the side of the neck, to assist its separation, from the parts below the base of the jaw, and from the pharynx. The pterygoid mus- cles were next detached, and the third branch of the fifth pair of nerves divided a little above the foramen at which it enters the hone, observing much caution to secure the safety of the trunk of the internal carotid, and deep-seated jugular both of which were exposed. At the several periods of this operation, the curved spatulas of Colles were found of infinite service, as in elevating the pa- rotid gland, keeping the tongue steady, &tc. Very little blood was lost in this ope- ration ; three arteries only, of any size, required a ligature : viz. the facial, lingua), and a little branch behind and under- neath the angle of the jaw. APPEJNDIX. luo After waiting for a little time to ob- serve if any hemorrhage should ensue upon the reaction of the system : the dap of the cheek was brought down and closely approximated to the divided inte- guments below by three interrupted sutures; after which, adhesive straps, lint, compress, and a double-headed roller, being applied, the patient was made, as comfortable as possible, and directed to be continued upon the table for a few hours to recruit. At eight o’clock in the evening she had been removed to her bed, and signified that she was comfortable. Some reaction of the circulation had taken place ; but there had been no hemorrhage. The pain from the operation she said was less than she had expected. For the first time since the operation she sipped three tea- spoonsful of cold water, and gave evi- dence by a nod that she could swallow. One hundred drops of tinct. opii was di- rected to be given if any twitching, more pain, or restlessness, should come on. She was recommended to make no effort to speak. 19 ih, 7 A. M. — She w’as found quite free of fever and irritation, and in every respect comfortable : she swallowed cold water by the tea-spoonful with but little inconvenience : she slept several hours during the, night. 12 at noon. — She was found comforta- ble ; skin moist; pulse less frequent, and soft : an enema was directed to be admi- nistered of soft soap and water; she had a little more difficulty in swallowing, but none in breathing. 9 P. M. — She was as well as in the morning ; the enema had operated three times, and relieved her ; pulse frequent, but not tense : she had taken about two ounces of cold water by the spoon since daylight. 20/A, 7 A. M. — She had had a very comfortable night ; instead of nodding, she answered yes and no to the several questions, in an audible whisper. 9 P. M. — She was much as in the morning. 21s/, 9 A. M. — Was as comfortable as yesterday morning. 9 P. M. — There was no material alter- ation. 22 d, 9 A. M. — An enema was directed to be administered as before. She was allowed to take, in addition to her cold water and teas, some thin chicken soup ; and was, in every respect, doing well. 9 P. M.— Tumefaction of the lips and cheek very trifling, not enough to effect the least change in the lids of the right eye. — Was in every respect comforta- ble. 24 tk, 1 1 A. M. — Has made no com- plaint. The wounds were dressed, and union by adhesion had taken place in their whole extent, excepting about the ligatures and sutures. Suppuration hav- ing come on about two of the sutures, were removed. Pulse about 120. — The adhesive straps were renewed, with lint interposed between them and the double-headed roller. 25 th. — Was every way comfortable. Pulse 120. 26/A. — She said she had no complaint to make. Pulse 80. She was directed to take a small dose of sulphate of mag- nesia. 27/A. — Spoke audibly, and said she was very well. Pulse about 84 28 Ih. — Was as well as before ; the wounds were dressed ; the two sutures at the upper part, near the ear, were removed ; wounds appeared heated, at every part except where the ligatures re main upon the arteries. Pulse 80. .2 9th. — Felt very well ; spoke dis- tinctly ; took freely of soup and other thin food. Pulse 100. Dec. 8 d . — Ligature from the carotid came away with the other three ligatures from the upper wound. A small collec- tion of matter was evacuated from under the integuments in the lower wound, which had been produced by the irrita- tion of the ligature. 4 th. — Spoke and swallowed very well ; wounds almost healed. Hits used for some days a wash of spirits and water to the mouth, with a view to correct some feetor of the saliva, and cleanse the mouth. 6 th. — She was found dressed, and sit- ting in an adjoining room, reading by the fire. She* looked and said she felt very w ell. The bandages being all left oft', the only deformity apparent was a little more tumefaction of the right cheek than the left ; wounds almost well : moved very readily the sound half of the under jaw. She was permitted to chew’ some animal food. 10/A. — Wounds all healed; made no complaint. March , 1822. — There was scarcely any perceptible deformity: the right cheek appeared, upon close examination, to be a little more depressed than the left; and some osseous deposit had commenced at the two situations at w hich the bone had bee n d i vi d ed . H er hea 1 1 h , i n e v t* ry respec t , was perfectly good, and she enjoyed the free use of the left side of the lower jaw. Maky Roe, a married woman, aged 22 years, came to New- York from Long- Island, on the 25th of March, 1822, to consult Dr. Mott concerning a tumefac- tion of the left side of her lower jaw-bone. She stated, that about one year from date there appeared an enlargement of the bone, at a point from which one of APPENDIX. m the molar teeth some time before had been extracted. That it continued to in- crease gradually ; but being at that time pregnant with her second child, and feeling little pain in the swelling, she took no particular notice of it. Since her delivery, however, which took place about six months before she came to the city, it has increased much more rapidly, but the pain remained as at first, and has been only felt occasionally to shoot through the part. This disease was much less extensive than that in the preceding case, but it reached from the base of the coronoid process to the first bicuspis tooth, ex- tending on each side of the bone to near the base, and as far back as the angle, at which part the base was comprehended in the disease. Several of the teeth had been thrust out by the growth of the tu- mour, and those which remained were very much displaced. The tumour had the same appearance and elastic feel of that in the former case. On the SOth March, at 12 o’clock, Dr. Mott, assisted by Drs. Post, Burro we-, and myself, tied the ieft carotid artery through an opening of about two inches in length opposite the thyroid cartilage ; and so lit- tle was the constitutional effect of this, that it was determined to proceed with the rest of the operation immediately. An incision through the integuments was now made, as in the former case, be- ginning over the condyloid process above the meatus auditorius, and carried in a semicircular direction below the base of the jaw, to terminate upon the chin a lit- tle under the lip. The flap of the cheek being dissected up, the first bicuspis tooth was extracted to prepare the way for the saw ; which instrument was then applied, and the bone divided in a perpendicular direction front that situa- tion. The masseter muscle was separa- ted from the angle of the jaw, and the parotid gland carefully elevated anteri- orly, in order to exhibit the hone a little above the angle, that room might be made for the saw. The bone was now cut through midway between the processes and angle, in aline parallel with the zygo- matic arch. The bone was now raised at the chin by the finger and thumb, then detached from the parts within the mouth by a scalpel, until the diseased mass was com- pletely removed. During the elevation of the flap, and removal of the bone, the hemorrhage was profuse. At least a dozen ligatures were applied to bleeding arteries ; some of the vessels bleeding equally free from both their extremities. The patient bore the operation with undaunted firmness, the flaps of integu- ment were brought together by several interrupted sutures, accompanied by ad- hesive straps and proper bandaging. The operation occupied one hour and fifty minutes. 7 o’clock, P. M.— Pulse 30 ; nodded that she was comfortable ; had slept lb minutes, and was refreshed, but was sick at stomach, and had made an effort to vomit ; ordered not to attempt to speak. 10 P. M. — Had coughed some, which was followed by a discharge of fresh blood from ttie mouth, as well as from the wound, so as to come through the bandage, and run upon the neck. Pulse 88 : had taken a little cold water by tea- spoonsful 31 st, to X. M» — Had a good night, but coughed hard several times, yet no more bleeding ; felt much refreshed from deep ; pulse y2; skin natural; took 10 drops tinct. opii to allay cough, but nausea be- ing the effect, was not repeated : to have cold barley water instead of common wa- ter, by the tea-spoonful. April ls£. — Passed an uncomfortable night, owing to cough ; pulse 02 ; was ordered enema communis , which was re- peated in the afternoon with good effect. Five P. M. pulse 120 to 135; articulates a little, though indistinctly ; was ordered a cough mixture. 2 d — More comfortable ; pulse 88 ; all symptoms favourable. No tumefaction about the eyelids ; cough less. 3d.— Felt refreshed ; countenance good ; no tumefaction of the face ; articulated distinctly ; pulse 88 ; complained of hun- ger. 8 P. M. pulse 80; cough was trou- blesome forepart of the day. mixt. ex- pect. cont. 4th. — Said with a distinct and audible voice that she was better than at any other time since the. operation ; felt no pain in the wound; coughed less; but from the state of the bandages, the wound was cleaned and dressed. The parts were found to look well; pulse 92; felt hungry ; was ordered some thin broth. 5th. — Had a comfortable night; took some chicken tea with much relish ; pulse 104; no appearance of tumefaction. Had an enema this morning which operated well ; cough much relieved. 6th. — Dressed ; removed from the up- per wound the sutures, and all the liga- tures except one ; parts looked well. The lower wound looked well ; but there was little union there by adhesion, proba- bly ow'ing to cough ; pulsq 80. 7th. — Has been sitting up in bed a lit- tle ; pulse 32 ; was ordered sulphate of soda in divided doses. 8th. — Improving daily; wounds doing well ; the last ligature from the upper wound was removed ; pulse 120. The increase of pulse probably owing to the operation of salts, which had just then taken place. APPENDIX. \ddy , & Co. of London, w hich does ap pear to me as infinitely sup* rior to any now in use, or likely to be contrived. There are tt\o very formidable objec- tions that I think must obtain against all the trusses, with that exception, and they are the follow ing : V hen the pad is firm- ly connected with the steel strap, it is clear, that in the different positions of the body, and constantly during progressive motion, pressure is made alternately by the one edge of the pad. then by the cen- tre, or the other odge ; and in proportion as the truss has been at first well applied, that is, with the more convex part of the pad against the ring, so the same centre of the pad n ay be the cause of strangulation of a portion of intestine or omentum, that should have been pei mil- ted to peep through the opening in the abdominal pnrietes.at a time when prer APPENDIX. • that situation which was to become the saphena, was cut upon with a scalpel, and about an inch of its length extracted. The integuments were brought together by adhesive plaster, and in about three weeks all the varices disappeared. I have been in the habit of puncturing these veins with a lancet, in several situa- tions at the same time ; and after they had bled freely, of dressing the limb with a compress and bandage, very systemati- cally applied, moistening the whole three or four times within the first twenty-four hours with the rectified spirits of w ine. By this treatment, the disease was very generally removed, provided it was not dependent upon constitutional circum- stances. T' 5 V» OP THR SBCONfc VOT.UMK, life LIBRARY OF THE JUL 1 u 1933 WajVWiSJtV fif IWMMM3. b .