bigram

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bigram frequency
com scientificreports833
creative commons557
influenza virus441
respiratory syndrome397
commons license334
virus infection321
acute respiratory286
scientificreports www272
amino acid254
gene expression253
syndrome coronavirus249
middle east239
east respiratory230
supplementary table229
epithelial cells228
performed using226
doc id224
rep doi224
sci rep224
cord uid224
viral rna192
respiratory tract176
immune response173
ebola virus173
competing interests173
days post169
present study163
scientific reports162
severe acute159
will need154
novel coronavirus152
springer nature151
infected cells151
published maps150
visit http150
obtain permission150
third party150
credit line150
jurisdictional claims150
indicated otherwise150
unless indicated150
party material150
nature remains150
remains neutral150
institutional affiliations150
appropriate credit145
give appropriate145
previously described145
statutory regulation145
permission directly145
copyright holder145
original author145
permits use145
permitted use145
intended use145
authors declare144
avian influenza144
intermittent fasting140
supplementary information138
infected mice138
statistically significant136
immune responses132
influenza viruses128
room temperature128
prostate cancer128
infectious diseases126
cell lines121
plasmodium falciparum119
international license112
commons attribution112
open access112
amino acids111
commons licence111
previous studies110
nucleic acid110
innate immune109
lung injury108
cell culture108
united states107
significantly higher105
spike protein105
ms plp105
flow cytometry104
coronavirus disease104
current study104
viral infection104
type i101
virus replication101
immune system99
week intermittent99
described previously99
mg ml98
org licenses97
cell line96
statistical analysis96
porcine epidemic96
negative control95
risk factors94
membrane fusion94
rna viruses94
western blot93
time pcr92
respiratory distress92
neutralizing antibodies92
reference genes91
note springer90
mg kg90
viral replication88
previously reported88
public health88
codon optimized88
zika virus87
electron microscopy87
stage hli85
taken together85
logistic regression84
gallic acid83
distress syndrome83
monoclonal antibodies82
protein expression81
neutrophil elastase81
clinical signs81
two groups80
thermo fisher80
significant difference80
reverse transcription79
wt mice78
phylogenetic analysis78
significant differences78
previous study77
ag seb76
escherichia coli76
control group76
viral load75
epidemic diarrhea75
host cell74
permissions information74
com reprints74
respiratory syncytial73
results suggest73
macro domain72
fisher scientific72
sample size71
transmissible gastroenteritis71
clinical characteristics71
three times71
ebov gp71
monoclonal antibody71
data analysis69
inflammatory cytokines69
syncytial virus69
goat anti69
results showed68
srep sha68
pr virus68
neutralizing antibody68
parainfluenza virus67
vaccine development67
mortality rate66
mechanical ventilation66
binding site66
stem cell66
disease virus66
data collection64
mouse model63
significantly lower63
positive selection63
hemorrhagic fever63
ng ml63
weight loss63
informed consent63
cov infection63
diarrhea virus62
coat protein62
significantly increased62
rndv expressing62
virus type62
dengue virus61
time points61
serum samples61
standard deviation61
dendritic cells61
ex vivo60
crystal structure60
cancer cells59
blot analysis59
systematic review59
expression levels59
statistical significance59
receptor binding59
total rna58
analyzed using58
stem cells58
polymerase chain57
cell surface57
disease severity57
gastroenteritis virus57
chain reaction56
bovine serum56
metabolic syndrome56
tagged ms56
sars coronavirus56
like receptor56
bat species56
cell epitopes56
binding affinity56
ventilator dependence56
hospital mortality55
infectious period55
nucleic acids55
antiviral activity55
differentially expressed55
respiratory disease54
important role54
saudi arabia54
life technologies54
active site54
ag cur54
genome sequences54
con con54
determined using53
stranded rna53
creat iveco53
licen ses53
viral infections53
intensive care53
org licen53
western blotting53
infectious bronchitis53
information accompanies53
coronavirus infection53
rabbit anti53
highly pathogenic53
iveco mmons53
pandemic influenza53
getv macro52
body weight52
class i52
respiratory viruses52
well plates52
dromedary camels51
lower respiratory51
immunodeficiency virus51
binding domain51
olive flounder51
viral clearance51
may also51
see supplementary51
lung cancer51
fever virus50
analysis using50
particle size50
circuit pressure50
sars fp50
human immunodeficiency50
analysis showed50
fold change50
virus infections49
wild type49
first time49
cell epitope49
plasma samples49
gum arabic49
antibody titers49
chikungunya virus49
rna binding49
clinical features48
determine whether48
genome sequencing48
reproduction number48
blood samples48
mass spectrometry48
human coronavirus48
bat paramyxovirus48
viral proteins48
signaling pathway48
disease control48
pseudotyped virus47
measured using47
spike glycoprotein47
rsv infection47
positive control47
virus disease47
endothelial cells47
treated cells47
time rt47
immune cells46
significantly reduced46
genome sequence46
human parainfluenza46
air conditioning46
infectious disease46
poly i46
pg ml46
antibody responses46
rna replication46
samples collected46
south korea46
two different46
rna virus45
breast cancer45
serum levels45
acute lung45
molecular dynamics45
differential expression45
high levels45
infected patients45
vesicular stomatitis45
also observed45
cell proliferation45
closely related45
social media45
kshv infection44
secondary antibody44
gp pseudotyped44
binding sites44
way anova44
total number44
mm nacl44
animal models44
viral genome44
results indicate44
large number44
innate immunity43
signaling pathways43
cells treated43
study design43
cell death43
final concentration43
statistical analyses43
respiratory failure43
well plate43
mm tris43
fruit bats43
inflammatory response43
like particles43
specific antibodies42
cb infected42
tract infections42
viral particles42
genomic dna42
lysis buffer42
also found42
cell migration42
sialic acid42
washed three42
influenza infection42
promoter activity42
epithelial cell42
fruit bat42
upper respiratory41
protective efficacy41
epitope prediction41
peripheral blood41
target genes41
cell viability41
recombinant protein41
blood pressure41
stomatitis virus41
bronchitis virus41
phylogenetic tree41
host cells41
cell responses41
relative humidity41
applied biosystems41
cohort study41
meo ma40
mononuclear cells40
th week40
subunit vaccine40
calculated using40
basic reproduction40
growth factor40
world health40
ms ms40
thermo scientific40
complete genome40
health organization39
vero cells39
fusion peptides39
real time39
helicobacter pylori39
hot spot39
cysvac advax39
tissue samples39
sars ifp39
clinical trials39
host species39
independent experiments39
flow rate39
rna polymerase39
heavy chain39
human transmission39
previous reports39
ethics committee39
virulent ibv39
binding protein39
septic shock39
feature selection39
tissue culture39
fluorescence intensity39
head group39
advax cpg39
quiescent stem38
neutrophil extracellular38
i interferon38
cytokine storm38
mrna expression38
severe covid38
corresponding author38
generation sequencing38
marburg virus38
hospitalized patients38
three different38
time point37
seasonal influenza37
reference gene37
even though37
coronavirus spike37
cov spike37
fatty acid37
virus entry37
control mice37
serially diluted37
culture medium37
viral loads37
domain iv37
molecular weight37
ge healthcare36
chimeric multiepitope36
infectious virus36
evaluated using36
isothermal amplification36
recent years36
dipeptidyl peptidase36
whole blood36
leaf blight36
recent study36
expression analysis36
viral protein36
positive cells36
lung tissue36
protease inhibitor36
nsp protease36
severe pneumonia36
graphpad prism36
virus glycoprotein36
results show35
sequence analysis35
tca cycle35
inflammatory cells35
antibody response35
dependent manner35
san diego35
cell types35
future studies35
cells expressing35
regression analysis35
reactive arthritis35
recent studies35
induced lung35
see table35
chest ct35
risk factor35
chikv nsp35
sample collection35
size distribution35
analysis revealed35
pdb id35
growth rate35
membrane protein35
human monoclonal35
standard curve35
buffered saline35
three independent34
intestinal epithelial34
risk score34
high level34
quantitative real34
host immune34
extracellular dna34
significantly different34
confirmed cases34
specific vhh34
infected animals34
structural proteins34
lateral flow34
oxidative stress34
mortality rates34
severe influenza34
mycobacterium tuberculosis34
drug delivery34
genetic diversity34
higher levels34
mers coronavirus34
congo hemorrhagic34
maximum likelihood34
cd cells34
delay propagation34
cell cultures34
molecular epidemiology34
igg antibody34
vaccine candidate34
life cycle34
fusion peptide33
post infection33
secondary structure33
sierra leone33
significantly decreased33
mrna levels33
converting enzyme33
serial dilutions33
analyte igg33
lymph nodes33
widely used33
transcription factor33
acute gastroenteritis33
clinical samples33
mice subjected33
polarization transfer33
protein kinase33
gastrointestinal symptoms32
hong kong32
mini kit32
mammalian cells32
social distancing32
adaptive immune32
mouse anti32
viral entry32
environmental factors32
factors associated32
nucleotide sequence32
age groups32
cell entry32
results indicated32
culture supernatant32
incubation period32
protein dimer32
lamina propria32
data suggest32
reasonable request32
treated mice32
chagas disease32
hli model32
erythrocyte invasion31
igg antibodies31
positive samples31
patients infected31
mice treated31
virus particles31
abasic pna31
generated using31
protective immunity31
apobec proteins31
rabbit igg31
sequence alignment31
nucleocapsid protein31
expressing codon31
mediated isothermal31
jamaican fruit31
protein sequences31
time series31
rna extraction31
clinical data31
ptm buffer31
pcr assay31
lung tissues31
luciferase activity31
day post31
dna vaccine31
care unit31
single nucleotide31
highly conserved31
assessed using31
cancer cell31
network analysis31
mdck cells31
gene segments31
dna constructs30
antibacterial activity30
commonly used30
reverse transcriptase30
santa cruz30
pcr using30
inhibitory effect30
human influenza30
chickens immunized30
equine antisera30
specific antibody30
financial interests30
relevant guidelines30
smoking cessation30
free energy30
lipid bilayers30
genbank accession30
mm hepes30
ibv strain30
extracellular traps30
nucleotide sequences30
light chain30
suppressor activity30
tgev infection30
elderly patients30
age distribution30
gel electrophoresis30
rhesus macaques30
transmission electron30
insulin resistance30
critically ill30
accession numbers30
early stage30
ebola entry30
human genome30
mainland china30
plaque assay30
confidence intervals30
cell lysates30
transmission dynamics29
cov rbd29
different concentrations29
fusion protein29
human infections29
plasma levels29
mdp values29
primary antibody29
cfu ml29
pathogenic avian29
strain mass29
specific igg29
paralichthys olivaceus29
porcine kobuvirus29
based assay29
tested positive29
pediatric patients29
wide range29
sequencing data29
rheumatoid arthritis29
survivor group29
pcr products29
acid sequences29
agarose gel29
previously published29
free water29
protein tag29
mice compared29
nervous system29
acid sequence28
experimental conditions28
regression model28
hours post28
quantitative pcr28
copy number28
findings suggest28
west africa28
diarrhoea seasonality28
also performed28
animal model28
immune activation28
animal care28
ill patients28
adenovirus type28
tlr expression28
lamp assay28
acid residues28
ibv vaccine28
gi disease28
purified using28
disease progression28
competing financial28
specific primers28
clinical outcome28
expressed genes28
indirubin derivatives28
clinical outcomes28
severe cases28
least one28
expression level28
respiratory infections28
mouth disease28
crispr cas28
white matter27
control measures27
rabies virus27
reactive protein27
high affinity27
mouse igg27
cytokine production27
pseudotyped hiv27
conjugated go27
case definitions27
marker genes27
kindly provided27
nasal turbinates27
severe disease27
clinical course27
polyclonal anti27
also showed27
whole genome27
skeletal muscle27
zikv challenge27
situation report27
detected using27
bl mice27
clinical symptoms27
hydrogen bonds27
ct values27
hepatocellular carcinoma27
molecular mechanisms27
colon epithelial27
protein levels27
surveillance system27
investigate whether27
impedance tomography27
ct score27
time reverse27
correlation coefficient27
organ dysfunction27
kg day27
rnai suppressor27
inflammatory cytokine26
target cells26
alexa fluor26
mhc class26
retrospective study26
vaccine construct26
evolutionary genetics26
datasets generated26
syndromic surveillance26
swab samples26
host range26
infected individuals26
quantified using26
virus titers26
rna structure26
critical role26
pcr amplification26
monoclonal anti26
hpiv species26
healthy controls26
wind speed26
sequence data26
contact tracing26
virus shedding26
ns protein26
tumor growth26
categorical variables26
per ml26
extracted using26
necrosis factor26
least stable26
blood cell26
influenza vaccine26
phage display26
chain version26
live ebov26
control groups26
human infection25
binding activity25
data indicate25
enzyme activity25
i ifn25
conventional method25
pcr analysis25
clinical trial25
electrical impedance25
newcastle disease25
silver nanoparticles25
tgev strains25
sample preparation25
increased expression25
human cells25
human adenovirus25
nlrp inflammasome25
univariate analysis25
body temperature25
water molecules25
cell cycle25
fetal bovine25
ml penicillin25
transfected cells25
influenza pneumonia25
ifnl mrna25
randomly selected25
virus rna25
open reading25
cell lysate25
ion torrent25
study period25
sanger sequencing25
iga responses25
per group25
ct value25
indirect elisa25
antibody levels25
airway epithelial25
phylogenetic analyses24
review board24
ileum epithelial24
endoplasmic reticulum24
structural basis24
respiratory infection24
bat rva24
conjugated goat24
rabbit haemorrhagic24
host defense24
viral titers24
bat guano24
cell marker24
lasv gp24
mm edta24
mouse monoclonal24
irradiation chamber24
clinical practice24
pcr system24
optofluidic platform24
insulin signaling24
negative controls24
pbs containing24
virus antigen24
dilution factor24
study showed24
obtained using24
viral nucleic24
national institute24
accession number24
secondary antibodies24
rna sequences24
may represent24
continuous variables24
resting eeg24
airborne iav24
anthelmintic drugs24
gene sequences24
recombination event24
data set24
central nervous24
protein interactions24
immunofluorescence assay24
alphavirus nsp24
corticosteroid use24
reading frames24
nervous necrosis24
supplementary tables24
mice infected24
biv pacing24
disease transmission24
dna polymerase24
haemorrhagic disease24
cb infection24
venom proteins24
institutional review24
cells infected23
tcid ml23
optimization problem23
significant increase23
optimal control23
lung inflammation23
luciferase reporter23
better understand23
pfu ml23
among children23
human respiratory23
negatively charged23
strains isolated23
hfmd patients23
small intestine23
type ii23
reading frame23
medical center23
bacterial gastroenteritis23
hybrid nps23
limited number23
activated protein23
previous report23
recombination events23
nonhuman primates23
deep learning23
respiratory pathogens23
pna probes23
extracellular matrix23
viet nam23
culture supernatants23
increased risk23
hav ig23
regression analyses23
nitric oxide23
capsid protein23
transmembrane domain23
bd biosciences23
spatially structured23
considered statistically23
structural protein23
shear stress23
curve analysis23
pbs buffer23
pdm infection23
animal experiments23
scanning electron23
authors reviewed23
copies per23
two viruses23
data sets23
aerosol method23
national institutes23
magnetic field23
femoral artery23
mg dl23
human health23
correlation coefficients23
fatality rate23
may lead23
significant reduction23
organ failure22
cell count22
bone marrow22
pdm mice22
tm ct22
inhibitory activity22
cells using22
aerosol samples22
control seasonal22
confidence interval22
adult patients22
necrosis virus22
bacterial leaf22
side chain22
national health22
assay kit22
expression profile22
dependence risk22
viral pathogens22
neutralizing monoclonal22
supplementary material22
vaccine candidates22
likely due22
stable reference22
oxygen saturation22
virtual screening22
iav densities22
signal transduction22
homing receptors22
retinoic acid22
ml streptomycin22
ang ii22
membrane potential22
studies showed22
also used22
community detection22
ad libitum22
dimer containing22
lung function22
ds patients22
plasma membrane22
protein structure22
pdm virus22
genomic rna22
proteomic analysis22
electron microscope22
tumor necrosis22
related genes22
specific antisera22
linked immunosorbent22
primary antibodies22
ifn signaling22
key role22
bacterial infections22
pulmonary disease22
replication competent22
first step22
virus transmission22
murine norovirus22
high degree22
human papillomavirus22
erythrocyte surface22
bacterial pathogens22
multiple sequence22
influenza surveillance22
whole region22
tb patients22
supplementary dataset22
protective antigen22
antiviral response22
per day22
phase i22
syndrome virus22
pcr product22
cell membrane22
dpp inhibitors22
machine learning22
target segment21
deficient mice21
linear regression21
conducted using21
significantly associated21
high risk21
polyclonal antibody21
interspecies transmission21
staphylococcus aureus21
porcine respiratory21
admission day21
epidemic diarrhoea21
age group21
th cells21
significance level21
neutralizing epitopes21
nucleotide positions21
coli lysate21
relatively small21
young children21
conjugated anti21
disease outbreaks21
road network21
nucleotide substitution21
uvc light21
thank dr21
method group21
library preparation21
recombinant viruses21
bhk cells21
absolute humidity21
cancer patients21
mrna translation21
air quality21
data showed21
may result21
least two21
per well21
tissue sections21
distilled water21
fusion proteins21
protein assay21
prediction model21
mean value21
serum albumin21
nuclear translocation21
using real21
clinical studies21
microwave power21
done using21
core protein21
population size21
post inoculation21
signal peptide21
chinese hamster21
assay using21
platelet count21
ebola infection21
vivo cultures21
ace ko21
nucleotide polymorphisms21
small number21
operating room21
positive patients21
distance matrix21
regulated genes21
clinical manifestations21
similar results21
science foundation21
delta inulin21
distal ribose21
several studies21
elderly group21
liquid chromatography21
model membranes21
ko mice21
chicken embryos21
reproductive number21
bacterial species21
expression system21
respiratory coronavirus20
null hypothesis20
biological processes20
autoimmune arthritis20
protein interaction20
proinflammatory cytokines20
neutralization assay20
cytopathic effect20
odds ratio20
freight trains20
time course20
endolysosomal calcium20
cell receptor20
proinflammatory cytokine20
niflumic acid20
standard deviations20
analysed using20
specific binding20
airborne microorganisms20
containing protein20
three days20
performed according20
polyacrylamide gel20
influenza incidence20
genome type20
west nile20
considered significant20
protease inhibitors20
image analysis20
signal intensity20
molecular evolutionary20
using two20
inflammatory responses20
receptor signaling20
pulmonary tuberculosis20
essential genes20
esrd patients20
endogenous control20
fold increase20
low levels20
infected livers20
pseudotyped viruses20
high mortality20
hz shx20
two weeks20
forward primer20
much higher20
pathway analysis20
expression studies20
dorsal horn20
expression data20
high expression20
thrombocytosis group20
transcriptome analysis20
median age20
ml niclosamide20
rna copies20
study demonstrated20
lymph node20
diabetes mellitus20
related patients20
high throughput20
host factors20
results obtained20
viral shedding20
malaria parasite20
spatial distribution20
batrachochytrium salamandrivorans20
encephalitis virus20
much lower20
also detected20
two days20
plasma sample20
individual differences20
molecular biology20
spinal cord20
new york20
ct images20
study also20
publicly available20
formic acid20
nodavirus antibody20
guinea pigs19
zikv infection19
nasal discharge19
bioaerosol sampling19
laboratory findings19
suckling piglets19
airborne influenza19
technical assistance19
virus infected19
cdna synthesis19
preterm infants19
reservoir hosts19
reported previously19
social network19
vascular endothelial19
interaction energy19
hydrophobic region19
sodium citrate19
cytokine levels19
test results19
hek cells19
time period19
higher number19
directed mutagenesis19
crystal structures19
red blood19
virus detection19
infective endocarditis19
virus binding19
dendritic cell19
use committee19
pcr primers19
study population19
results demonstrated19
population density19
hierarchical clustering19
based approach19
directional changes19
dpp expression19
vaccinia virus19
table shows19
force field19
conformational changes19
least three19
dna viruses19
citric acid19
confocal microscopy19
regulatory factor19
transmission rate19
iii iv19
transgenic mice19
years old19
virucidal effect19
approved drugs19
cov nucleocapsid19
immunosorbent assay19
salivary protein19
copies ml19
ari episodes19
cleavage site19
crucial role19
virus strains19
multiple sclerosis19
pneumonia patients19
written informed19
terminal region19
molecular basis19
virus neutralization19
macrophage activation19
novel human19
human erythrocytes19
urinary nephrin19
log fold19
cells well19
buffer containing19
next generation19
human movement19
using different19
gastric cancer18
power density18
may contribute18
future work18
body mass18
white blood18
protein concentration18
data interpretation18
egyptian fruit18
acid substitutions18
nile tilapia18
epidemic size18
card deficiency18
sp parasites18
experimental infection18
domain ii18
porcine reproductive18
sham controls18
government effectiveness18
protein sequence18
coronavirus hku18
binding motifs18
human plasma18
one hour18
disease outbreak18
energy metabolism18
spatial super18
sir model18
fecal nucleic18
human macrophages18
cell signaling18
transmembrane protein18
quantitative reverse18
vaccinated animals18
new coronavirus18
cell response18
central air18
exercise training18
strand rna18
patients admitted18
computed tomography18
ibv protection18
isolated individuals18
conserved among18
commercially available18
host response18
electric field18
iu ml18
dna damage18
false positive18
signal overlap18
uv light18
antibody fragments18
nasal spray18
bacterial blight18
induced apoptosis18
overlapping genes18
side effects18
fold higher18
ct scans18
rna synthesis18
collected data18
horseradish peroxidase18
surface area18
results demonstrate18
final volume18
lipid bilayer18
rotavirus strains18
calcium phosphate18
igg indirect18
insectivorous bats18
expression profiles18
three weeks18
early phase18
investigated whether18
resonant frequency18
common pipistrelle18
cell activation18
pfcrn expression18
showed significantly18
seir model18
rabbit polyclonal18
plasmid dna18
infected subjects18
coding sequences18
results suggested18
bacillus anthracis18
reference genome18
transmission routes18
ct scan18
protein synthesis18
donor pigs18
filovirus igg18
early stages18
sense rna18
wild birds18
healthy subjects18
functional analysis18
dynamics simulations18
induced arthritis18
dmem containing18
mm sodium18
respiratory illness18
upper airway17
southern china17
washed times17
vice versa17
blood cells17
may help17
biosafety level17
kidney disease17
likelihood method17
energy transfer17
target microorganisms17
antiviral activities17
expression vector17
using primers17
genomic sequences17
virus genomes17
ms analysis17
asthma exacerbation17
rbd binding17
human host17
essential role17
southeast asia17
virus ns17
inactivation ratio17
hcv infection17
new england17
dna replication17
blocking agents17
using graphpad17
disease spread17
positive correlation17
glutamic acid17
genetics analysis17
chicken eggs17
neutralisation assay17
falciparum malaria17
human mobility17
higher mortality17
tuberculosis infection17
viral genomes17
pm concentrations17
rva strains17
renilla luciferase17
geometric mean17
asthma seasonal17
chifit gene17
terminal domain17
direct contact17
sofa score17
survival rate17
hoc test17
symptom onset17
tumor cell17
natural reservoir17
time detection17
bone mineral17
incubated overnight17
antibody production17
also thank17
pseudotyped vsv17
ifit proteins17
corticosteroid treatment17
prion infection17
elongation complex17
comparative analysis17
rna interference17
validation cohort17
urine samples17
conditioning system17
medium containing17
cov fp17
possible role17
tandem repeats17
like domain17
web server17
inhibitor cocktail17
pfripr antibodies17
using anti17
cell debris17
confocal microscope17
drug discovery17
pfcrn gene17
normally distributed17
sybr green17
transmission events17
antigen presentation17
fold serial17
luciferase assay17
coronavirus pneumonia17
bal fluid17
human igg17
log copies17
isg expression17
influenza hemagglutinin17
cruz biotechnology17
host shifts17
cell growth17
social behavior17
virus via17
gold nanoparticles17
dna sequences17
knockout mice17
emergency department17
genome copies17
infected groups17
hantavirus infection17
latent period17
infected cases17
fc receptor17
controlled trial17
final epidemic17
coding sequence17
antiviral drugs17
pcr assays17
obstructive pulmonary16
high dose16
neutralisation assays16
viral pneumonia16
ig titers16
different time16
future research16
pten overexpression16
virus titration16
random walk16
cytokine release16
bacterial growth16
virus neutralisation16
human subjects16
protein identification16
cytokine responses16
may provide16
nk cells16
new insights16
african genotype16
surface pm16
time periods16
cell differentiation16
bayesian inference16
wound healing16
virus titer16
public transportation16
detection kit16
genome types16
elisa plates16
rrna gene16
laser ablation16
acute phase16
medical research16
class ii16
previously shown16
higher level16
quantitative analysis16
vitro transcription16
vaccine design16
early detection16
lavage fluid16
housekeeping genes16
multiepitope vaccine16
human neutralizing16
rank test16
exact test16
antibody repertoire16
macro domains16
ionic strength16
ha protein16
liquid nitrogen16
ribosomal rna16
cell adhesion16
two distinct16
one day16
visualized using16
central role16
also significantly16
novel avian16
host proteins16
ms coat16
interferon regulatory16
drug targets16
three groups16
based vaccine16
case fatality16
alveolar macrophages16
location information16
standard error16
samples using16
retrospective cohort16
mbl gene16
mitochondria isolated16
variant tgev16
random effect16
promoter region16
endothelial growth16
heart disease16
super variable16
human antibody16
relatively low16
npc domain16
medical records16
software version16
zika igg16
severe patients16
chronic obstructive16
past infection16
broadly neutralizing16
cell pellets16
containing fbs16
proteins identified16
binding pocket16
clinically relevant16
virus protein16
highly expressed16
respiratory virus16
binding buffer16
hind limb16
graphpad software16
emerging infectious16
loaded onto16
probably due16
software package16
fecal samples16
related complications16
reverse genetics16
bacterial inoculum16
allowed us16
diagnostic sensitivity16
fluorescence microscopy16
npm protein16
enzymatic activity16
phylogenetic trees16
poor prognosis16
also known16
good agreement16
tumor cells16
polyclonal antibodies16
viral fusion16
reactive oxygen16
washed twice16
dipolar mode16
control strategies16
specific pathogen16
recombinant virus16
well known16
indoor air16
ebov neutralisation16
cholesterol accumulation16
clinical presentation16
recombinant proteins16
small sample16
three areas16
healthy individuals16
gene ontology15
identify genes15
conformational epitopes15
dna sequence15
cell membranes15
complex networks15
monte carlo15
highly correlated15
england biolabs15
hepg cells15
four hours15
activation syndrome15
heat shock15
free dmem15
copy numbers15
one week15
differential gene15
filovirus antigen15
individual samples15
tissue damage15
induced inflammation15
sequence identity15
human disease15
molecular docking15
simplex virus15
biological replicates15
inflammatory bowel15
term memory15
control samples15
specific cd15
fasting compared15
straight line15
surface plasmon15
enteric viruses15
ig products15
influenza strains15
physicochemical properties15
eye drop15
also tested15
abnormal elevation15
membrane curvature15
fold dilutions15
prolonged mechanical15
influenza cases15
molecular degree15
huh cells15
stat activation15
image processing15
hydrogen bond15
plasmon resonance15
landscape compatibility15
hcv rna15
magnetic resonance15
constructed using15
increased levels15
hiv gp15
gal receptors15
highly sensitive15
live attenuated15
antibody binding15
blood vessels15
negative results15
porcine rotavirus15
lung pathology15
infection control15
total protein15
discovery cohort15
roc curve15
peste des15
ion channel15
one study15
severe dengue15
throughput sequencing15
nile virus15
rna samples15
data generated15
bacterial communities15
cell type15
random effects15
significantly enriched15
better understanding15
protection experiment15
mm imidazole15
cell survival15
chronic kidney15
ace interaction15
asthmatic mice15
antiviral effect15
malaria parasites15
feline calicivirus15
risk areas15
aligned using15
disease surveillance15
highly contagious15
compared using15
among patients15
showed significant15
might also15
calf serum15
tested using15
cytoplasmic domain15
normal aging15
growth rates15
min pi15
molecular diagnostic15
ambient noise15
aerosol route15
relative risk15
exposed patients15
tract infection15
des petits15
observational study15
selected based15
gene symbols15
associated coronavirus15
sensitivity analysis15
rna using15
ibv challenge15
test number15
overall mdp15
codon usage15
ifit gene15
structural part15
aging process15
stimulated genes15
bowel disease15
statistical computing15
normal distribution15
health care15
climatic factors15
human mers15
general population15
pbs group15
environmental dna15
abdominal pain15
treatment group15
prosocial behavior15
reaction mixture15
four different15
au nps15
site residues15
pathogen infection15
immunized chickens15
antiviral therapy15
health commission15
related viruses15
method using15
pathogenic isolates15
empty vector15
enveloped viruses15
serological cross15
differences among15
platelet counts15
test whether15
mucosal immunity15
active tb15
intestinal tract15
large scale15
petits ruminants15
igg responses15
blood flow15
sgta ablation15
bat coronavirus15
full genome15
nanopore sequencing15
optical density15
bone formation15
cells cultured14
internal control14
natural science14
independent risk14
data bank14
first two14
rna detection14
ii iii14
marine predators14
like receptors14
responses induced14
like illness14
freight traffic14
northern italy14
ethics statement14
fixed paraffin14
gene family14
ra plus14
symptomatic infections14
dnase turbo14
size reduction14
coding region14
cold pbs14
first study14
higher expression14
pm concentration14
days later14
gel phase14
solution containing14
cardiac aes14
institutional animal14
niclosamide treatment14
incubation phase14
different species14
independent factors14
hcv replication14
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buffered formalin14
analysis reveals14
forest virus14
north american14
silico analysis14
severe sepsis14
culture plates14
without pards14
national natural14
merozoite invasion14
rna secondary14
stranded dna14
alveolar epithelial14
malaria vaccine14
aspartic acid14
acid pairs14
observational studies14
molecular mechanism14
blood group14
significant changes14
gel filtration14
using specific14
recently reported14
affinity selection14
two types14
sodium dodecyl14
conditional autoregression14
genetic variation14
prepared using14
surveillance data14
dromedary camel14
control genes14
genes involved14
transiently transfected14
spike gene14
pipistrelle bat14
binding lectin14
high resolution14
mice showed14
target gene14
limb ischemia14
rndvs expressing14
transcription polymerase14
hubei province14
virus isolation14
aptamer chimera14
stat phosphorylation14
dna binding14
herpes simplex14
rad laboratories14
significant correlation14
megena modules14
recognition receptors14
protein bands14
protein binding14
candidate reference14
physical dilution14
positively selected14
mechanical hyperalgesia14
low dose14
data obtained14
parameter estimation14
zika vrna14
essential medium14
antimicrobial activity14
temporal dynamics14
pilot study14
molar ratio14
peptide binding14
prv hnx14
gp spike14
reads mapping14
coronavirus associated14
bacterial phyla14
viral genomic14
batcov hku14
disease network14
included studies14
anthrax toxin14
gia activity14
patient samples14
murine irf14
indirect elisas14
log reduction14
protein family14
amplified using14
east asia14
pdm group14
dependent rna14
ifit genes14
ifitm proteins14
close proximity14
biological characteristics14
authors thank14
human ifit14
significantly inhibited14
antibody repertoires14
significantly less14
lps group14
heptad repeat14
infected population14
final manuscript14
dnase i14
two strains14
multivariate logistic14
species transmission14
dodecyl sulfate14
wuhan university14
spike proteins14
primary human14
based vaccines14
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ser ala14
significant association14
bronchoalveolar lavage14
data show14
infected hepatocytes14
primer sequences14
supplementary materials14
beckman coulter14
several limitations14
japanese encephalitis14
infection prevention14
forming units14
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blocking buffer14
cell lung14
poultry companies14
mortality risk14
mers patients14
interaction term14
predictive value14
antihyperalgesic effect14
mortality among14
relative expression14
also demonstrated14
post hoc14
secretor status14
viral dilution14
high frequency14
infectious periods14
late stages14
examined whether14
ray images14
two independent14
using lipofectamine14
mk cells14
gse qnpbytap14
acquired pneumonia14
mfon patients14
influenza pandemic14
origin influenza14
molecular evolution14
spinal dorsal14
ethical committee14
incidence risk14
oxygen species14
mean values13
major role13
chicken ifit13
anthropic noise13
cells compared13
plate reader13
ectopic expression13
kidney injury13
positive results13
positive controls13
pseudomonas syringae13
plaque purification13
autoregression term13
ic values13
zoonotic viruses13
mem medium13
recombination analysis13
sequence similarity13
human norovirus13
elisa system13
lymphocyte subpopulations13
purification kit13
mirna expression13
decreasing trend13
lung epithelial13
reverse primer13
endosomal escape13
dimer interface13
neutralizing epitope13
aerosol particles13
high performance13
drug administration13
mineral density13
streptococcus agalactiae13
control cells13
supplementary figs13
inflammation biomarkers13
glycosylation sites13
road networks13
test trials13
bone resorption13
negative regulation13
assay system13
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drug design13
strand synthesis13
mean age13
inclusion criteria13
influenza season13
study group13
cytokine expression13
climate factors13
mannheimia haemolytica13
haemorrhagic fever13
kj mol13
yellow fever13
side chains13
epitopes using13
also reported13
iav infection13
study clinical13
rna genome13
genomic sequence13
cynomolgus macaques13
developing solution13
cys ala13
md simulations13
component analysis13
month follow13
immunomodulatory activity13
mbp segment13
recombinant pfripr13
substitution rate13
icc staining13
viral titer13
syringae pv13
airborne transmission13
cas system13
discovery rate13
risk hpv13
cytoplasmic tail13
large numbers13
virus np13
sivelestat sodium13
reporting system13
expression pattern13
case series13
mutant viruses13
biphasic calcium13
cho cell13
per reaction13
virus core13
first days13
web search13
replication cycle13
publication bias13
data indicated13
study provides13
transition time13
immune cell13
chang gung13
signal amplification13
prcv strain13
positive fecal13
stimulating factor13
adaptive evolution13
multiplex pcr13
linear mixed13
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default parameters13
leaves inoculated13
clinical diagnosis13
acid metabolism13
false discovery13
nasal cavity13
tissue tropism13
paving pattern13
human receptor13
expression stability13
secreting cells13
deep sequencing13
full length13
neural networks13
aqueous solution13
host responses13
structured conditional13
final version13
old spf13
viral hemorrhagic13
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corticosteroid therapy13
dna sequencing13
puerto rico13
described elsewhere13
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fusion activity13
may play13
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infectious dose13
reversible exchange13
impact score13
human lung13
plasma pools13
infections among13
virus polymerase13
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achieved using13
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respiratory viral13
microbe interactions13
phase ii13
membrane topology13
autoimmune diseases13
propensity score13
pulmonary tb13
deliciosa leaves13
natural hosts13
severe respiratory13
infect humans13
expressed proteins13
rapid detection13
kcal mol13
viral membrane13
elution buffer13
commercial live13
crude rubi13
pr hv13
sendai virus13
remains unclear13
human rotavirus13
ctl epitopes13
gene silencing13
ccid ml13
igg levels13
two additional13
raw data13
chicken embryo13
virus production13
left panel13
mucosal immune13
acute asthma13
genomic characterization13
made available13
regional differences13
pseudomonas aeruginosa13
fold changes13
small molecules13
transcription factors13
mineral oil13
structure determination13
imaging system13
tetratricopeptide repeat13
enhanced ppe13
high sensitivity13
human gene13
lower bound13
higher risk13
antiviral effects13
master mix13
aedes aegypti13
red cell13
xanthomonas oryzae13
indirect immunofluorescence13
plus tgev13
spot region13
square test13
regional ventilation12
worth noting12
human brain12
infection induces12
cancer progression12
renal failure12
possibly due12
weighted degree12
water ad12
tertiary structure12
genetic characterization12
subgroup analysis12
flow cytometric12
life sciences12
jackson immunoresearch12
extracellular trap12
diarrhoea virus12
nicotine administration12
experimental setup12
cardiac surgery12
el paso12
virus load12
maternal immune12
lower levels12
serum free12
wearable device12
electron spin12
study demonstrates12
predators algorithm12
transgenic chicken12
atomic resolution12
immunofluorescence staining12
mitochondrial dysfunction12
protocol cii12
sindbis virus12
methods used12
primary enterocytes12
carnivore rabv12
highly connected12
exported protein12
outbreak response12
also examined12
spleen tissues12
many studies12
family members12
passenger trains12
genes enriched12
five times12
two short12
human nasal12
studies will12
symptoms onset12
viral antigen12
mbp target12
shock protein12
epr spectra12
research council12
pmn migration12
may cause12
ifitm expression12
chagas panel12
virus vaccine12
dna methylation12
inspired oxygen12
outbreak detection12
long sharp12
ethical approval12
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severity scores12
challenge virus12
bat sera12
detergent micelles12
showed high12
principal component12
urgent need12
map kinase12
total volume12
severe clinical12
dna fragments12
mice immunized12
salicylanilide anthelmintic12
news outlets12
conditioning systems12
data used12
viral envelope12
surface proteins12
also evaluated12
marine fish12
protein quantification12
gene usage12
suckling pigs12
protein data12
hcv clearance12
common among12
elevated co12
native pfripr12
pulsed laser12
pseudorabies virus12
batrachochytrium dendrobatidis12
live poultry12
specific iga12
trypanosoma cruzi12
immune evasion12
sequence diversity12
ct findings12
significant genes12
tracheal swab12
coronavirus infections12
small glutamine12
among age12
aerosolized viruses12
ebola gp12
viral sequences12
airway epithelium12
passenger traffic12
complete coding12
number gse12
multiple testing12
molecular probes12
treg cells12
ablated particles12
chikv replication12
i peak12
pulmonary infection12
severity score12
surface protein12
mechanisms underlying12
transcription start12
hemorrhagic shock12
peptidase iv12
quality control12
lethal dose12
first draft12
scoring system12
human activity12
uv exposure12
modelling study12
light scattering12
membrane dehydration12
virus infectivity12
gene transcription12
fluorescence microscope12
nhbe cells12
cd cd12
clinical disease12
ace blocking12
membrane proteins12
cell counting12
density lipoprotein12
dengue hemorrhagic12
putative hydrophobic12
odds ratios12
elementary school12
swine respiratory12
canada goose12
disease ratio12
early warning12
functional receptor12
opioid receptor12
positive rate12
translational modifications12
induced acute12
epidemiological data12
slightly higher12
barr virus12
multiple organ12
effect term12
data analyses12
pcr kit12
uninfected control12
cystic fibrosis12
first case12
pao fio12
may explain12
positively charged12
target cell12
field intensity12
mobile phase12
heart rate12
ut cells12
blood mononuclear12
cell counts12
spin labels12
packaging signals12
prosocial concern12
secondary structures12
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type hadv12
directional change12
methods section12
protein structures12
small cell12
stably expressing12
nested pcr12
niclosamide inhibits12
corona virus12
estrogen receptor12
specific motifs12
qpcr analysis12
allele mrna12
operating rooms12
sharp straight12
emerging viruses12
patients may12
systemic inflammation12
hcv genome12
olfactory information12
accessory proteins12
weeks old12
case report12
negative sense12
hcl ph12
spatiotemporal model12
mortality associated12
penton base12
associated protein12
hadv dna12
phosphate buffered12
plasma concentrations12
phase transition12
ir catalyst12
protective effect12
series analysis12
detection rate12
using three12
bubble bursting12
power transfer12
blood glucose12
studies reported12
blocking vaccine12
potent neutralization12
different types12
invasion phenotype12
laboratory animals12
pt strain12
epitope mapping12
influenza epidemics12
human enterovirus12
based detection12
current status12
oreochromis niloticus12
also present12
mammalian cell12
developing countries12
log ec12
data demonstrate12
lassa virus12
start site12
weighted distance12
adverse effects12
slightly different12
lung disease12
humoral immunity12
less severe12
study revealed12
pb mutants12
comparative elisa12
gastrocnemius muscle12
clinical use12
domain i12
inflammatory effects12
reporter plasmids12
protein concentrations12
reverse primers12
camel mers12
myeloid cells12
pore size12
analysis version12
cardiac output12
previously demonstrated12
systemic immune12
receptor dpp12
lesser extent12
vaccinated mice12
disulfide bonds12
bronchial asthma12
nucleosome assembly12
immune mediators12
tumor suppressor11
cd expression11
strong positive11
patient tnbc11
body fluids11
dnase treatment11
go terms11
main operating11
rneasy mini11
pearson correlation11
missing data11
mass spectrometer11
infected pneumonia11
nerve ligation11
first wave11
virus strain11
novo assembly11
penicillin streptomycin11
air pollution11
test zone11
bronchial epithelial11
cell infiltration11
povidone iodine11
induced cell11
dna rna11
evolutionary relationship11
latin american11
stress response11
protease domain11
mice undergoing11
common ancestor11
shell decomposition11
control sample11
chain monte11
significantly improved11
like protease11
comparative study11
per mouse11
remains unknown11
model showed11
ophthalmia neonatorum11
rotavirus genotypes11
pedv spike11
fl signals11
tissue engineering11
per sample11
transfection reagent11
immunogenic proteins11
inflammatory drugs11
highly immunogenic11
highly virulent11
open public11
significantly altered11
diagnostic test11
discharged patients11
panel viruses11
community cohort11
haplotype pairs11
rectal swabs11
midwest city11
campylobacter jejuni11
among regions11
coronavirus replication11
unstructured random11
fluorescence quenching11
fmdv rna11
transferred onto11
higher oligomer11
spf chicken11
respiratory symptoms11