bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
pl pro	173
respiratory syndrome	140
acute respiratory	118
cov pl	101
severe acute	100
syndrome coronavirus	84
cell culture	79
influenza virus	67
infl uenza	60
epithelial cells	59
virus infection	57
type i	55
hcv ns	54
immune response	51
novel coronavirus	49
avian influenza	47
respiratory tract	46
viral rna	45
cp therapy	43
hemorrhagic fever	41
middle east	40
east respiratory	40
innate immune	40
pregnant women	39
cord uid	39
sin doi	39
doc id	39
virol sin	39
stress granule	38
viral load	38
stress granules	36
ifn production	34
viral replication	33
vaccinia virus	33
influenza viruses	32
dengue virus	32
cell lines	32
recombinant vaccinia	32
immune responses	31
respiratory disease	30
lung injury	29
sg formation	29
like protease	29
sars coronavirus	29
public health	28
culture models	28
cov infection	28
infectious diseases	27
inflammatory responses	26
saudi arabia	26
ad cells	26
nucleic acid	26
adenovirus type	25
resplex ii	25
i ifn	24
raft cultures	24
hantavirus infection	24
ln group	24
cell epitopes	24
infected cells	24
life cycle	23
highly pathogenic	23
cr kptecs	23
seasonal influenza	23
animal models	23
gene expression	23
rna viruses	22
innate immunity	22
hexon gene	22
monoclonal antibodies	22
protein kinase	22
vaccinia viruses	22
granule formation	21
disease severity	21
en group	21
cell cultures	21
convalescent plasma	21
coronavirus disease	21
rabies virus	21
risk factors	20
vero cells	20
virus replication	20
human adenovirus	20
infected patients	20
converting enzyme	19
viral infection	19
lower respiratory	19
neutralizing antibody	19
epidemic hemorrhagic	19
clinical features	18
crystal structure	18
host cells	18
ub complex	18
simplex virus	18
culture system	18
herpes simplex	18
human papillomavirus	18
organotypic raft	18
ag mice	18
prolonged positivity	18
antiviral response	18
mice immunized	18
human coronavirus	17
authors declare	17
weight loss	17
culture systems	17
coronavirus infection	17
uenza virus	17
renal syndrome	17
spike protein	17
cell line	16
post infection	16
ns protein	16
lung tissues	16
important role	16
antiviral drugs	16
infectious disease	16
host innate	15
innate antiviral	15
vaccine strain	15
human viruses	15
cellular immune	15
monoclonal antibody	15
diarrhea virus	15
epidemic diarrhea	15
hong kong	15
porcine epidemic	15
neutralizing antibodies	14
day post	14
tiantan strain	14
virologica sinica	14
ebola virus	14
acute lung	14
binding protein	14
ace protein	14
previous studies	14
ev infection	14
early warning	13
rna granules	13
i interferon	13
zika virus	13
hepatitis virus	13
health organization	13
negative group	13
amino acids	13
world health	13
supplementary material	13
swine influenza	13
stranded rna	13
may also	13
genomic dna	13
processing bodies	13
multiplex pcr	12
confirmed cases	12
reverse transcription	12
epithelial raft	12
clinical symptoms	12
hydrogen bond	12
inflammatory cytokines	12
mammalian cells	12
camel milk	12
upper respiratory	12
rna interference	12
pathogenic avian	12
gene therapy	12
structural proteins	12
multiplex rt	12
amino acid	12
taqman rt	12
results showed	12
cytopathic effect	12
translation initiation	12
host cell	12
plasma therapy	12
human coronaviruses	11
seasonal infl	11
porcine respiratory	11
two viruses	11
syncytial virus	11
rnai suppression	11
immune cells	11
dna viruses	11
respiratory syncytial	11
viral loads	11
primary human	11
human respiratory	11
symptom onset	11
swine infl	11
recombinant vaccine	11
two viral	11
immune system	11
infectious virus	11
host interactions	11
influenza vaccine	11
case report	11
viral pathogens	11
pulmonary edema	11
raft culture	11
cells infected	11
receptor binding	11
viral variants	11
disease complex	11
homologous recombination	11
type ii	11
vsr activity	10
recombinant plasmid	10
two patients	10
extracted using	10
positive farms	10
porcine circovirus	10
clinical manifestations	10
antibody response	10
viral proteins	10
binding proteins	10
ill patients	10
influenza vaccines	10
coronavirus papain	10
days post	10
avian infl	10
animal subjects	10
northern blotting	10
rights statement	10
tissue engineering	10
infection model	10
widely used	10
coronavirus associated	10
hela cells	10
human rights	10
tract infections	10
antibody titer	10
drug discovery	10
pcr amplification	10
genome sequence	10
clinical characteristics	10
dimensional cell	10
multiparous sows	10
suppress rnai	10
mouse hepatitis	9
severe covid	9
emerging human	9
human cells	9
accessory proteins	9
within days	9
critically ill	9
organotypic epithelial	9
fusion protein	9
way anova	9
western blot	9
hantavirus infections	9
distress syndrome	9
subjects performed	9
mice infected	9
proximal tubule	9
hantavirus pulmonary	9
weeks old	9
binding site	9
pcr products	9
respiratory distress	9
pulmonary syndrome	9
recombinant adenovirus	9
lung tissue	9
risk factor	9
hexon protein	9
antiviral agents	9
disease control	9
nps specimens	9
antibody responses	9
bronchial epithelial	9
large number	9
granule assembly	9
cancer cell	9
specific shrna	9
conditional reprogramming	9
suppression activity	9
cell entry	8
clinical samples	8
molecular epidemiology	8
time points	8
antibody titers	8
tissue culture	8
cancer cells	8
cell responses	8
test results	8
respiratory viruses	8
chinese academy	8
emerging infectious	8
dub activity	8
survival rate	8
nonstructural proteins	8
virus strains	8
western blotting	8
two cases	8
host range	8
respiratory specimens	8
coronavirus spike	8
specific humoral	8
fatality rate	8
vaccine candidate	8
statistically significant	8
recent progress	8
hiv infection	8
natural science	8
viral infections	8
ct value	8
initiation factor	8
human ubiquitin	8
nucleocapsid protein	8
mortality rate	8
cells cultured	8
long term	8
cells expressing	8
wuhan city	8
adenovirus vaccine	8
significant differences	8
viral particles	8
valley fever	8
prdc presentation	8
nonstructural protein	8
uenza viruses	8
new coronavirus	8
rift valley	8
length np	8
serologic test	8
human infections	8
statistical analysis	8
pediatric inpatients	8
united states	8
viral entry	8
recent years	8
culture model	8
virus tiantan	8
adaptive immune	8
science foundation	8
hepatocellular carcinoma	8
universal influenza	8
arms race	8
denv infection	8
target cells	8
cov orf	7
time pcr	7
epithelial cell	7
viral genomic	7
human transmission	7
specific antibodies	7
rna helicase	7
differentiation potential	7
different species	7
binding domain	7
south korea	7
bl loop	7
human keratinocytes	7
rna silencing	7
nucleic acids	7
host interaction	7
human infection	7
protein expression	7
rnai pathway	7
core protein	7
vaccine development	7
present study	7
nucleotide sequence	7
antiviral immunity	7
alveolar macrophages	7
inflammatory cells	7
virus titer	7
severe disease	7
even though	7
human liver	7
early negative	7
lentiviruses pseudotyped	7
suspected cases	7
hajj pilgrims	7
mainland china	7
lethal infection	7
infected people	7
closely related	7
disease virus	7
functional receptor	7
human immunodeficiency	7
immunodeficiency virus	7
respiratory viral	7
different groups	7
lamp assay	7
ascitic fluid	7
rna binding	7
control measures	7
papillomavirus type	7
fcr activation	7
like proteases	7
protease inhibitor	7
clinical course	7
raw camel	7
total rna	7
nk cells	7
antiviral activity	7
considered statistically	7
authorized users	7
egfp mrna	7
codon usage	7
cov nsp	7
southern china	7
viral genome	7
acid test	7
complete hexon	7
viral life	7
protein response	7
ex vivo	7
severe lung	7
well plates	7
dengue viruses	7
antiviral drug	7
isatin derivatives	7
years old	7
circovirus type	7
inclusion bodies	7
unfolded protein	7
black arrow	7
positive control	7
th day	7
mouse models	7
mouth disease	7
virus disease	6
porcine reproductive	6
ct images	6
necrosis factor	6
viral hepatitis	6
drug design	6
virus strain	6
transmembrane domain	6
biological evaluation	6
high levels	6
pcr assays	6
virus culture	6
nsp nsp	6
nervous system	6
two different	6
previous study	6
normal human	6
lg ml	6
mrna levels	6
protease inhibitors	6
genomic rna	6
coronavirus nsp	6
novel avian	6
ub complexes	6
mouse model	6
infection induces	6
dengue viral	6
women infected	6
actinobacillus pleuropneumoniae	6
syndrome virus	6
tumor necrosis	6
saudi moh	6
first time	6
may play	6
significantly higher	6
online version	6
strain gz	6
total rnas	6
viruses including	6
cell interactions	6
virus type	6
viral diseases	6
bronchiolar epithelial	6
second immunization	6
i ifns	6
reverse transcriptase	6
cj mice	6
vaccine production	6
severe critical	6
patients infected	6
gingival epithelium	6
sendai virus	6
hospitalized children	6
bamh i	6
rna polymerase	6
fusion antigen	6
iv gtt	6
measured using	6
may provide	6
model systems	6
inhibitory effects	6
alveolar septum	6
rna virus	6
infected mice	6
protein inhibits	6
severe clinical	6
human kidney	6
late negative	6
purified ace	6
th th	6
protective immunity	6
described previously	6
pathological changes	6
deficient mice	6
ifn receptor	6
cytokine storm	6
observational study	6
kidney injury	6
vascular leakage	6
alveolar cells	6
pooled peptides	6
laboratory diagnosis	6
see text	6
ubl domain	6
three times	6
cov papain	6
specimens collected	6
chronic diseases	6
mg ml	6
recent study	6
encoding egfp	6
murine coronavirus	6
protein involved	6
cell immunity	6
igg antibodies	6
previously described	6
sequence analysis	6
analysis showed	6
phylogenetic analysis	6
time taqman	6
respiratory virus	6
antiviral immune	6
balb cj	6
term culture	6
igg antibody	6
wild birds	6
contains supplementary	6
health care	6
enp induced	6
incubation period	6
substrate specificity	6
ace expression	6
world society	6
studies showed	6
hcv infection	6
tubule cells	6
viral gene	6
evans blue	6
clinical outcomes	6
host antiviral	6
virus vaccine	6
plasmids encoding	6
accessory protein	6
early stage	6
like receptors	6
electronic supplementary	6
time rt	6
associated coronavirus	6
traditional chinese	6
fusion gene	6
transmissible gastroenteritis	6
chain amide	6
expression system	6
higher levels	6
sg assembly	6
adaptive immunity	6
quantitative rt	5
human covs	5
significantly different	5
wall vessel	5
essential role	5
dna damage	5
human beings	5
laboratory tests	5
virus subtypes	5
coronavirus infections	5
infected animals	5
ct scans	5
mononuclear cells	5
three patients	5
xho i	5
virus infections	5
pcr product	5
mycoplasma hyopneumoniae	5
genome encodes	5
structural basis	5
qiagen resplex	5
departing pilgrims	5
incidence rate	5
infected individuals	5
cellular factors	5
respiratory pathogens	5
genotypes detected	5
viral shedding	5
oxide synthase	5
chronic hepatitis	5
chain reaction	5
cell response	5
general population	5
korean hemorrhagic	5
ethics committee	5
significantly associated	5
cell death	5
foci forming	5
vitro cell	5
clinical isolate	5
fetal bovine	5
nsp genes	5
class i	5
early stages	5
substrate binding	5
human adenoviruses	5
defective hadv	5
green fluorescence	5
infectious viral	5
canine kidney	5
like structures	5
central nervous	5
bat sl	5
bovine serum	5
factors associated	5
cl protease	5
antiviral innate	5
whether hcv	5
novel human	5
antiviral compounds	5
ifn induction	5
kinase pkr	5
block fcr	5
cells using	5
conditionally reprogrammed	5
also demonstrated	5
pp ab	5
specific antibody	5
binding affinity	5
host mrna	5
cell surface	5
structure genes	5
virus monoclonal	5
viral culture	5
cell types	5
informed consent	5
induces formation	5
respiratory failure	5
containing fbs	5
suppress ifn	5
vs rvj	5
jinyintan hospital	5
induced significantly	5
inhibitory activity	5
investigate whether	5
reading frame	5
viral rnas	5
plasmid pet	5
adenovirus vectors	5
ace receptor	5
viral pathogenesis	5
newly discovered	5
immunized mice	5
cells grown	5
rna replication	5
viral protein	5
studying human	5
severe illness	5
cervical cancer	5
neutralization test	5
coronavirus hku	5
goat anti	5
temporal profile	5
gamma globulin	5
negative control	5
patients might	5
infect humans	5
clinical analysis	5
pandemic influenza	5
cov pathogenesis	5
ii ifn	5
female patient	5
human cases	5
zoster virus	5
penton base	5
seven isolates	5
qpcr assays	5
viruses causing	5
rotavirus infection	5
viruses genotypes	5
national natural	5
virus may	5
viral nucleic	5
coronavirus pneumonia	5
infection models	5
total nucleic	5
different cell	5
human influenza	5
tubule epithelial	5
global health	5
cr cells	5
bacterial agents	5
neurogenic pulmonary	5
human viral	5
viral dna	5
spike proteins	5
viral growth	5
human sars	5
dna sequencing	5
cohort study	5
empty vector	5
retrospective study	5
transmission dynamics	5
ace mrna	5
analyzed using	5
virus ns	5
cov replication	5
eukaryotic translation	5
puumala virus	5
key role	5
higher frequencies	5
mosquito cells	5
functional characterization	5
adenovirus vector	5
feeder cells	5
inhibits hiv	5
different covs	5
highly contagious	5
older age	5
viral clearance	5
severe respiratory	5
significant risk	5
might also	5
rabbit anti	5
sg components	5
drug development	5
innate immunosuppressive	5
human disease	5
host responses	5
close contact	5
serum samples	5
kidney proximal	5
gastrointestinal symptoms	5
specific sfcs	5
eif alpha	5
dependent rna	5
serum antibody	5
luciferase activity	5
fusion antigens	5
well plate	5
also detected	5
santa cruz	5
final manuscript	5
hospital stay	5
monoplex real	5
limited number	5
cell model	5
dna polymerase	5
fever virus	5
viral genes	5
virus induces	5
oxyanion hole	5
pb components	5
ub binding	5
median ct	5
host immune	5
determine whether	5
among groups	5
case fatality	5
ns gene	5
national health	5
activated protein	5
infectious agents	5
indirect immunofluorescence	5
stress response	5
mouse igg	5
nitric oxide	5
human cytomegalovirus	5
htnv seov	5
data showed	5
different disease	5
new york	5
covalent complex	5
entry efficiency	5
antiviral rnai	5
organ failure	5
transgenic mice	5
fatality risk	5
reference standard	5
kptecs using	5
one day	5
pb proteins	5
forming assay	5
virus titers	5
medical university	5
pregnant woman	5
plasmid encoding	5
conserved epitopes	5
facilitates viral	4
lactate dehydrogenase	4
correlated significantly	4
simultaneous detection	4
inflammatory response	4
monoplex rt	4
hcv replication	4
limited infection	4
female balb	4
committee meeting	4
viral strains	4
electron microscopy	4
magnetic levitation	4
neutralizing activity	4
causing ards	4
viruses also	4
novel mechanism	4
angiotensin converting	4
culture supernatant	4
phylogenetic trees	4
wuhan university	4
cov spike	4
virus isolated	4
high level	4
kinetic assays	4
intravenous immunoglobulin	4
papainlike protease	4
respiratory diseases	4
open reading	4
body weight	4
soft agar	4
interspecies transmission	4
species transmission	4
covs might	4
zoonotic viruses	4
infection causes	4
clinical severity	4
i ii	4
lymphocyte count	4
differences among	4
lethal dose	4
free pl	4
still limited	4
ion channel	4
molecular basis	4
dimensional culture	4
plasmid pjsc	4
human bocaviruses	4
mammalian stress	4
repair dna	4
inhibition test	4
using two	4
strand rna	4
inhibitors targeting	4
directly bind	4
specific cellular	4
disease caused	4
promotes cell	4
data suggest	4
health commission	4
model using	4
virion host	4
chinese medicine	4
endonucleolytic cleavage	4
linked sialic	4
functional motif	4
two variants	4
positive rates	4
protein interacts	4
flow bioreactor	4
type vaccine	4
direct contact	4
sulfonyl isatin	4
cov genome	4
pathogenic human	4
mediated inflammatory	4
authors read	4
may cause	4
hcv nonstructural	4
largely unknown	4
pseudotyped viruses	4
antiviral responses	4
cov cases	4
novel approach	4
polymerase chain	4
cells transfected	4
antiviral effects	4
cell rna	4
four copies	4
using pcr	4
blood samples	4
serious public	4
cr condition	4
bat origin	4
physiologically relevant	4
human papillomaviruses	4
gapdh mrna	4
human health	4
vivo model	4
acid amplification	4
respiratory system	4
plus panel	4
different plaque	4
seven viruses	4
binding activities	4
two groups	4
ii plus	4
lamp method	4
clinical outcome	4
better understanding	4
taken together	4
provide new	4
loads determined	4
four coronaviruses	4
also increased	4
hemagglutination inhibition	4
modified vaccinia	4
human ace	4
terminal domain	4
pcr kit	4
gene silencing	4
structural protein	4
even death	4
binding sites	4
factor alpha	4
host restriction	4
old female	4
coronavirus receptor	4
primary gingival	4
multiple functions	4
human metapneumovirus	4
human airway	4
ev antigen	4
isothermal amplification	4
early diagnosis	4
cancer research	4
enzymatic activity	4
nsp protein	4
rna probe	4
infected pregnant	4
alveolar space	4
panel pre	4
peripheral blood	4
cause severe	4
surrounding tissues	4
host gene	4
ifn responses	4
reverse genetics	4
pig farms	4
humoral immunity	4
site cys	4
including lungs	4
induced rnai	4
respiratory illness	4
deubiquitinating activity	4
research program	4
cells well	4
common cold	4
pkr activation	4
mers cases	4
graphpad prism	4
kidney functions	4
saudi arabian	4
mouse anti	4
interferon antagonist	4
hiv aids	4
human normal	4
restriction enzyme	4
mild moderate	4
dendritic cells	4
expression level	4
spleen cells	4
bat coronaviruses	4
human diseases	4
viral dsrna	4
scientific research	4
data indicated	4
covalent mers	4
acute kidney	4
previously known	4
viral antigen	4
mouse sera	4
gene source	4
severe cases	4
review summarizes	4
ev receptor	4
diagnostic system	4
probe targeting	4
viruses using	4
molecular mechanisms	4
hypertensive covid	4
negative farms	4
type strain	4
study also	4
loading control	4
negative controls	4
viral suppressor	4
alpha phosphorylation	4
irf activation	4
persistent viral	4
catalytic efficiency	4
rvf outbreak	4
intermediate hosts	4
unpasteurized camel	4
shed light	4
pfu denv	4
internal proteins	4
via northern	4
highly conserved	4
viral proteases	4
epithelial tissue	4
reduce mortality	4
rna synthesis	4
laboratory animal	4
host shutoff	4
stem cell	4
odds ratio	4
prevent virus	4
ncov infection	4
identifi ed	4
differentiated human	4
monitored daily	4
seven days	4
warning models	4
first identified	4
assisted diagnostic	4
retrospective observational	4
transcription factors	4
new human	4
avian coronaviruses	4
matrix protein	4
rapid antigen	4
alkaline phosphatase	4
renal failure	4
increased risk	4
virus transmission	4
turned negative	4
virus challenge	4
established long	4
cell biology	4
icu admission	4
thawed three	4
lineage function	4
pcr sensitivities	4
imported case	4
synonymous codon	4
molecular biology	4
pshuttle plasmid	4
pandemic virus	4
sp viruses	4
stimulated gene	4
examine whether	4
sialic acids	4
cell lysates	4
cell strains	4
miscellaneous conditions	4
barr virus	4
see whether	4
sequence identity	4
days later	4
cell tropisms	4
epidemiological studies	4
written informed	4
mrna decay	4
one year	4
results indicate	4
treatment may	4
three major	4
coli system	4
ct scan	4
antibody test	4
na proteins	4
double knock	4
antibody tests	4
monoplex taqman	4
ethical standards	4
proteintech group	4
available data	4
rna sequencing	4
basic cell	4
author contributions	4
tract infection	4
copy number	4
control virus	4
mers patients	4
epsilon epitope	4
control efforts	4
nt sirna	4
renal proximal	4
dimensional tissue	4
young children	4
adenoviral respiratory	4
causing severe	4
future studies	4
arg forms	4
complete genome	4
newly identified	4
significant difference	4
virus rna	4
cell apoptosis	4
respiratory infections	4
van duinen	4
humoral immune	4
clinical information	4
significant impact	4
receptor ace	4
ct values	4
alexa fluor	4
rna decay	4
signaling pathways	4
coronavirus nonstructural	4
viral envelope	4
prospectively collected	4
isolated viruses	4
labeled rna	4
active site	4
first committee	4
kidney cells	4
severe pneumonia	4
parainfluenza virus	4
different stages	4
previously reported	4
responses induced	4
examined via	4
gastroenteritis virus	4
normal cells	4
underlying mechanism	4
infect cells	4
extraction kit	4
potential therapeutic	4
literature review	4
emergent human	4
peritoneal cavity	4
safety evaluation	4
moving average	4
reported cases	4
myeloma cells	3
ccl cells	3
novel viruses	3
copies per	3
recent advances	3
standard strains	3
reaction buffer	3
similar results	3
remains elusive	3
pedv strains	3
binding patterns	3
well studied	3
usage bias	3
protective immune	3
high viral	3
deubiquitinating activities	3
main chain	3
fi eld	3
hiv protease	3
current understanding	3
proteolytic processing	3
pb formation	3
mrna transcripts	3
continuous passages	3
potential platform	3
heart disease	3
like illness	3
moh website	3
rapid assessment	3
cases co	3
prolonged viral	3
ii pneumocytes	3
dependent enhancement	3
ns contains	3
cell migration	3
stimulated genes	3
study group	3
newly emerging	3
many viruses	3
control program	3
vaccine strains	3
remains unclear	3
immune evasion	3
gingival keratinocytes	3
recognition receptors	3
hiv infected	3
monkey kidney	3
sequestrating dsrna	3
england biolabs	3
data suggested	3
influenza infection	3
trizol reagent	3
deisgylating activity	3
cell science	3
risk hpv	3
vaccine vector	3
numbering scheme	3
dengue disease	3
natural reservoir	3
methyltransferase activity	3
laboratory findings	3
immortalized human	3
facilitate virus	3
like domains	3
ifn deficient	3
among humans	3
positive cells	3
modelling study	3
gel electrophoresis	3
independent growth	3
may differ	3
ifn expression	3
using trizol	3
coronavirus nucleocapsid	3
membrane fusion	3
late pregnancy	3
time series	3
labeled dsrna	3
ns protease	3
cell signaling	3
medical conditions	3
cov nsps	3
provide insights	3
receptor recognition	3
pcr method	3
model system	3
constructed based	3
immortalized cell	3
hypertensive ones	3
mrna cap	3
various mechanisms	3
rna recognition	3
virus rvj	3
transcription factor	3
viral host	3
liver cancer	3
confidence interval	3
day prior	3
airway epithelia	3
human renal	3
target different	3
heterologous influenza	3
may contribute	3
protein binds	3
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virus virion	3
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darby canine	3
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van kerkhove	3
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results suggested	3
two weeks	3
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human seasonal	3
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using viral	3
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ace shedding	3
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hydrogen bonds	3
clinical benefit	3
viral pathogen	3
probe design	3
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stomatitis virus	3
hepg cells	3
aiv subtypes	3
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south korean	3
doublestranded rna	3
th august	3
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inducible nitric	3
capsid proteins	3
nab complex	3
second antibody	3
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study provides	3
late promoter	3
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term cell	3
abidol hydrochloride	3
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coronavirus rna	3
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wt mice	3
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nps aliquot	3
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institut pasteur	3
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mouse th	3
creative commons	3
sg nucleation	3
hcv biology	3
african green	3
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fever clinical	3
infectious pathogens	3
important antiviral	3
total nps	3
china acknowledgements	3
chinese center	3
future plans	3
health interventions	3
andmouth disease	3
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mass spectrometry	3
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cellular mrnas	3
tubulin antibodies	3
fetal death	3
transcriptional gene	3
primary inflammatory	3
commonly used	3
cells established	3
first two	3
protein also	3
super spreading	3
rabbit igg	3
help understand	3
human angiotensin	3
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autonomous region	3
culture plates	3
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slightly serious	3
signal transduction	3
flua pandemic	3
might help	3
cellular genes	3
candidate vaccine	3
host species	3
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intrapulmonary bronchial	3
chimeric genomes	3
ns plasmid	3
agarose gel	3
causing human	3
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inhibits translation	3
blot analysis	3
ifn antagonism	3
small rnas	3
tbk ikk	3
cytopathic effects	3
translation inhibition	3
west nile	3
nitrocellulose membrane	3
antiviral therapy	3
lung inflammation	3
australian hajj	3
influenza strains	3
ge healthcare	3
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either empty	3
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multiple cloning	3
moderately serious	3
igg complex	3
tour group	3
sialic acid	3
sars model	3
ha protein	3
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region ii	3
cell proteins	3
study showed	3
sp myeloma	3
growth curves	3
enp vs	3
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productive infection	3
rapid viral	3
two sars	3
renal disease	3
valuable tool	3
lead compound	3
cov enzyme	3
pulmonary imaging	3
placental barrier	3
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renmin hospital	3
nylon membrane	3
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viral disease	3
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leader sequence	3
pulmonary inflammation	3
protein induces	3
also found	3
using rt	3
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square test	3
viruses carrying	3
two days	3
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recent outbreak	3
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viral suppressors	3
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protein nsp	3
medicine tanreqing	3
terminal residues	3
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ct findings	3
four parallel	3
infectious human	3
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one patient	3
models may	3
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expression vector	3
secondary bacterial	3
rabbit serum	3
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pig kidney	3
ace rabbit	3
chinese government	3
vaccine candidates	3
polymerase involved	3
contributed equally	3
proteins tia	3
encoding multiple	3
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capsid genes	3
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helicase domain	3
clinically approved	3
seventeen isolates	3
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van riel	3
three mice	3
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carbonyl oxygen	3
showed similar	3
family members	3
malignant cells	3
acid replacement	3
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mediated isothermal	3
murine hepatitis	3
evolutionarily conserved	3
color change	3
sl rna	3
descriptive study	3
increased fluorescence	3
visual detection	3
significant neutralizing	3
encode viral	3
final volume	3
horseshoe bats	3
selective inhibitors	3
publicly available	3
cultures provide	3
microcarrier beads	3
pb assembly	3
median length	3
one nps	3
fi nal	3
novel platform	3
hydrophobic interactions	3
understanding sars	3
borne hcv	3
organ dysfunction	3
forming unit	3
virtual screening	3
drug screening	3
cp transfusion	3
highly variable	3
production induced	3
human rabies	3
dennis lo	3
also provide	3
much longer	3
tlr family	3
adult human	3
expressing ha	3
primer pairs	3
conformational change	3
enzymatic assays	3
murine sars	3
new england	3
patients showed	3
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affinity chromatography	3
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viral internal	3
induced silencing	3
pv strain	3
animal studies	3
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parallel wells	3
ii assay	3
transcription loop	3
dna vaccine	3
inhibits type	3
including influenza	3
puerto rico	3
individuals infected	3
buffer mmol	3
may develop	3
main protease	3
induces sg	3
determined using	3
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initial velocities	3
acute renal	3
associated disease	3
internal genes	3
cerebrospinal fluid	3
tissue damage	3
recovered patients	3
low level	3
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studying viral	3
logistic regression	3
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virus envelope	3
copies ml	3
vaccine expressing	3
induced apoptosis	3
serially diluted	3
cruz biotechnology	3
ii multiplex	3
clinical disease	3
multiple vsrs	3
toward inducing	3
np gene	3
airway epithelial	3
received cp	3
traced back	3
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coronavirus replicase	3
microculture neutralization	3
prevent cov	3
spanish influenza	3
prediction limit	3
stranded rnas	3
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novel recombinant	3
pcr possessed	3
many different	3
containing serum	3
mice deficient	3
rnase inhibitor	3
structural studies	3
igm antibody	3
pathogen interactions	3
complete hadv	3
might explain	3
binding domains	3
eukaryotic cells	3
sindbis virus	3
million people	3
models used	3
vaccine design	3
sequence similarity	3
ace interaction	3
pb component	3
inhibitory effect	3
coli bj	3
i restriction	3
viruses must	3
first report	3
antiviral rna	3
silencing assay	3
cytokines including	3
sirna production	3
study period	3
around twofold	3
viral pneumonia	3
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china cdc	3
parental strain	3
van reeth	3
seasonal human	3
surface ha	3
huh cell	3
protein synthesis	3
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nt dig	3
hubei province	3
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ace function	3
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multiplex resplex	3
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severe diseases	3
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human bronchial	3
fever complicated	3
rnai induced	3
dengue fever	3
nasal epithelial	3
dna copies	3
also showed	3
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atypical pathogens	3
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coronavirus accessory	3
virion assembly	3
complex may	3
korea cdc	3
zoonotic potential	3
strains isolated	3
human epithelial	3
hbeag secretion	3
human cell	3
inducible gene	3
adaptor protein	3
white blood	3
inoculation immunization	3
detected using	3
pregnant patients	3
baculovirus expression	3
group received	3
various truncated	3
virus growth	3
vaccine induces	3
acid extraction	3
different steps	3
ray crystallographic	3
phosphorylated eif	3
surveillance system	3
using magnetic	3
commercial pig	3
dependent manner	3
resulting plasmids	3
vesicular stomatitis	3
vascular permeability	3
terminal cards	3
develop universal	3
catalytic domain	3
adenovirus rad	3
humanized mice	3
infectious cdna	3
mild symptoms	3
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discharged patients	3
viral mrnas	3
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gel shift	3
lopinavir ritonavir	3
protein promotes	3
interferon receptor	3
plaque size	3
will provide	3
cov might	3
nephropathia epidemica	3
virus detection	3
replication sites	3
cat kidney	3
established mouse	3
existing medical	3
china novel	3
important roles	3
clinical trials	3
might contribute	3
phyllanthus emblica	3
studies revealed	3
exfoliated epithelial	3
organoid cultures	3
zinc ion	3
serious health	3
infection may	3
sars epidemic	3
compound named	3
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multiple organ	3
recent studies	3
cov plpro	3
pasteurella multocida	3
several limitations	3
membrane matrix	3
third dimension	3
culture medium	3
ifn signaling	3
health emergency	3
parainfluenza viral	3
future direction	3
critical role	3
possessed specificities	3
infectious bronchitis	3
type hadv	3
viruses may	3
suppressing rnai	3
pr challenge	3
conserved residues	3
lysis buffer	3
cells showed	3
results indicated	3
may lead	3
rna copy	3
haemorrhagic fever	3
interstitial pneumonia	3
first antibody	3
therapeutic tools	3
risc assembly	3
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mov inhibits	3
accession numbers	3
like receptor	3
subgenomic mrnas	2
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palm civet	2
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different hosts	2
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ddr response	2
sars virus	2
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poct diagnosis	2
previous reports	2
hbeag levels	2
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several multiplex	2
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either inoculated	2
chain carbonyl	2
indicated time	2
complex binding	2
whether ev	2
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ch hljh	2
associated kidney	2
rotavirus induces	2
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encoding ns	2
bryan cullen	2
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mcs models	2
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mouse monoclonal	2
effi cacy	2
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i mda	2
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mtor signaling	2
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therapy including	2
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markov model	2
like coronavirus	2
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cells represent	2
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adenovirus replication	2
produce infectious	2
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animals positive	2
suspected mers	2
two major	2
widespread attention	2
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protein interactions	2
sars patients	2
also play	2
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virus vp	2
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hbv dna	2
acid recovery	2
early outbreak	2
novel visual	2
fibrin deposition	2
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detection bias	2
epitheliotropic viruses	2
replicate efficiently	2
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cells display	2
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adding ace	2
pcr reaction	2
nuclear mrna	2
binding specificity	2
findings indicate	2
reported studies	2
trailer rna	2
cd epitopes	2
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rnai suppressor	2
specific primers	2
kit possesses	2
group died	2
prokaryotic expression	2
culture vaccine	2
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array detection	2
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study influenza	2
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main target	2
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multiple sequence	2
include various	2
infectious clone	2
higher antibody	2
diffuse alveolar	2
ray structure	2
kinetic assay	2
amplification method	2
magnetic cell	2
developing regions	2
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imaging improvement	2
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qiaquick gel	2
live pedv	2
human hepatoma	2
may stimulate	2
influenza nucleoprotein	2
remove isg	2
alveolar epithelium	2
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copy per	2
virus pb	2
provide cross	2
wide host	2
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kidney diseases	2
viral lower	2
like assemblies	2
models will	2
connect virologists	2
blue dye	2
homologous regions	2
similar inflammatory	2
treat patients	2
hcv core	2
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tissues including	2
mrna precursor	2
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wuhan outbreak	2
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specialized hospital	2
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nonhuman primate	2
intestinal epithelial	2
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dynamic interaction	2
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different tissues	2
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decahydroisoquinolin scaffold	2
plaque variants	2
viral proteinase	2
also induces	2
without changing	2
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nucleotide excision	2
er stress	2
specimen process	2
xray structural	2
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dynamic characteristics	2
severe consequences	2
dimensional radial	2
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sp cells	2
dig antibody	2
methylprednisolone mg	2
similar research	2
fetal malformations	2
sulfate precipitation	2
alveolar damage	2
within weeks	2
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within two	2
search model	2
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first week	2
technology might	2
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fidelity dna	2
ns proteins	2
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severe patients	2
crispr cas	2
also cause	2
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model analysis	2
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human cd	2
tract human	2
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peritonitis virus	2
different nonhuman	2
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adenovirus infections	2
pb segment	2
response including	2
high shear	2
throat swab	2
dual infections	2
fi nishing	2
priority research	2
across species	2
antibody detection	2
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ternary complex	2
new knowledge	2
two strains	2
coronavirus cell	2
enterovirus infection	2
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lung impairment	2
conditions like	2
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glycoprotein ligand	2
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age years	2
large population	2
model also	2
target enriched	2
pb core	2
screen reveals	2
seov infection	2
neutrophil numbers	2
secondary cases	2
fatal inflammatory	2
emerged middle	2
resembles self	2
cellular responses	2
cellular models	2
specific role	2
online rna	2
vaccine provides	2
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based methods	2
suspension array	2
adult inpatients	2
coli dh	2
binds argonaute	2
organ damage	2
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aa identity	2
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virus expressing	2
escherichia coli	2
week old	2
virus interacts	2
conserved asp	2
deadly hcovs	2
grey dots	2
structure protein	2
cresol red	2
renal insufficiency	2
infectious hcv	2
milk secretion	2
well tissue	2
described elsewhere	2
blood cell	2
first three	2
diffraction data	2
dependent cell	2
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pilgrims reported	2
fever subsided	2
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hbv activity	2
multiplexing rt	2
represented one	2
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i sg	2
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fragment containing	2
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septic shock	2
transmembrane proteins	2
antigen detection	2
prdc results	2
serial ct	2
similar replicative	2
findings provide	2
reproducible results	2
life river	2
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fold higher	2
two parts	2
high degree	2
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virus transmitted	2
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following infection	2
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membrane formation	2
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acid detection	2
performed using	2
cov drug	2
cyclooxygenase expression	2
tumor progression	2
preemptive approach	2
precursor processing	2
various times	2
cases show	2
vital river	2
pkr dimerization	2
cov knowledge	2
early late	2
river laboratory	2
isg genes	2
per reaction	2
lung parenchyma	2
chinese horseshoe	2
protein vaccines	2
human case	2
hydrophobic patch	2
common viral	2
worth noting	2
bovine coronavirus	2
igg polymers	2
future development	2
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electronic medical	2
classical pathway	2
reprogrammed human	2
later stage	2
host translation	2
imposes stress	2
ifn pathway	2
congenital heart	2
hbx gene	2
protein specifically	2
recent emergence	2
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th days	2
ii panel	2
improve basic	2
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avian viruses	2
viral evasion	2
variation trend	2
prothrombinase fibroleukin	2
patients diagnosed	2
stimulate cd	2
cov nucleocapsid	2
health problems	2
mutational analysis	2
species boundaries	2
rna might	2
main goal	2
conventional influenza	2
megalin cubilin	2
two overlapping	2
analysis confirmed	2
positively expressed	2
major swine	2
magnetic particle	2
traditional cancer	2
slightly concerned	2
mdck cells	2
lytic infection	2
feline caliciviruses	2
international concern	2
engineering protein	2
shock syndrome	2
reported sars	2
virus nucleoproteins	2
endogenous peroxidase	2
fi ndings	2
effective vaccine	2
early events	2
novel mammalian	2
deadly covs	2
basic training	2
cytokine responses	2
distinct severe	2
organ cultures	2
longer time	2
provided evidence	2
levitation method	2
lethal diseases	2
simulated microgravity	2
virus hijacks	2
asian genotype	2
result showed	2
human virus	2
varicella zoster	2
faster decline	2
measles virus	2
bats may	2
one month	2
spike gene	2
existing humoral	2
different extents	2
human plasmacytoid	2
genomic sequences	2
zhejiang province	2
cellular receptors	2
tissue sections	2
urgent treatment	2
sampling time	2
different topics	2
swine flu	2
wuhan nodavirus	2
ten days	2
brome mosaic	2
per well	2
containing four	2
positive proportion	2
confers heterosubtypic	2
colorimetric lamp	2
positive clones	2
analyzing spheroids	2
subcellular localization	2
cov infected	2
primary antibodies	2
fbwz oxp	2
hamster kidney	2
point mutations	2
intramuscular groups	2
affect viral	2
partially understood	2
various types	2
virus ankara	2
population doublings	2
immunological characteristics	2
different viral	2
foci sizes	2
ml dapi	2
hbv infection	2
response plays	2
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producing infectious	2
observing cytopathic	2
developing severe	2
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clinical progression	2
spleen mononuclear	2
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enriched multiplexing	2
emerging coronaviruses	2
coronavirus replication	2
people around	2
original clinical	2
ml cscl	2
igg level	2
coronavirus group	2
downstream effectors	2
pro shows	2
human alveolar	2
tyrosine kinases	2
available viruses	2
technologies corporation	2
deisgylating activities	2
activities towards	2
great interest	2
viral strain	2
missing links	2
will focus	2
macrophages infected	2
form colonies	2
kinetic curves	2
potential tool	2
findings show	2
originally designed	2
ajolu rh	2
case detection	2
mortality within	2
nucleocapsid proteins	2
multicellular tumor	2
slightly lower	2
also positive	2
respiratory adenoviruses	2
fusion cells	2
mrna degradation	2
studies involving	2
monomer switch	2
competent mutants	2
also shown	2
initial incubation	2
cov epidemic	2
routine covid	2
placental transmission	2
ago via	2
normal ranges	2
ev receptors	2
cov stains	2
moderate symptoms	2
derived small	2
pandemic spread	2
reassortant virus	2
nonproductive infection	2
vaccine approved	2
eagle medium	2
cosmopolitan genotype	2
disease modeling	2
mice without	2
ub comprises	2
based devices	2
two types	2
high potency	2
mouse lethal	2
encoded proteins	2
protective antibody	2
splicing factor	2
foci reduction	2
serologic tests	2
compensatory emphysema	2
tract samples	2
linked immunospot	2
kristina broliden	2
wasting syndrome	2
vaccinia ankara	2
risk level	2
host factors	2
independent experiments	2
cells directed	2
dimensional keratinocyte	2
mathematical modelling	2
genetic variation	2
inflammatory drugs	2
different mechanisms	2
aspartate aminotransferase	2
mainly focus	2
expressed successfully	2
inhibitor lopinavir	2
also induced	2
virus segment	2
hiv nucleoside	2
yellow fever	2
syndrome inhibitor	2
cell system	2
human gamma	2
protein complex	2
antiviral signaling	2
rapid increase	2
deficiency syndrome	2
plasmid prad	2
coding region	2
necrotizing enteritis	2
metagenomic nextgeneration	2
host epithelial	2
impacts stress	2
median age	2
pseudoviruses showed	2
strong antibody	2
many viral	2
transmembrane serine	2
human neurons	2
structural insights	2
viruses expressing	2
detection limits	2
np fusion	2
tandem repeats	2
adenovirus types	2
tumor spheroid	2
rapid classification	2
dual inhibitors	2
different genotypes	2
key target	2
disease outbreak	2
possible mechanism	2
peroxidase labeled	2
rodent hosts	2
viral receptors	2
better replication	2
cell populations	2
oncolytic viruses	2
therapy protocols	2
specific receptors	2
similar clinical	2
attenuated adenovirus	2
nsp complex	2
typical clinical	2
optimized suspension	2
targeting cov	2
cr technology	2
given human	2
screening antiviral	2
targeting coronavirus	2
gene contributes	2
direct immunofluorescence	2
like polarized	2
species specific	2
early february	2
efficient propagation	2
bat covs	2
ns wt	2
possible underlying	2
fatal acute	2
dicer cleavage	2
bronchial lavage	2
pseudovirion infection	2
two covid	2
sensitivities correlated	2
encoding hcv	2
assay sensitivities	2
high titers	2
rna transcription	2
protein complexes	2
immune signaling	2
warmstart colorimetric	2
urological system	2
recent pneumonia	2
activation may	2
cellular entry	2
rna sensor	2
western blots	2
enormous threat	2
histopathological changes	2
new technologies	2
rna stress	2
vaccine rad	2
blood donors	2
prospective study	2
associated virus	2
culture using	2
high affinity	2
viral cellular	2
valle del	2
attack rate	2
reactive hyperplasia	2
hcv rna	2