This is a list of all the questions and their associated study carrel identifiers. One can learn a lot of the "aboutness" of a text simply by reading the questions.
| identifier | question |
|---|---|
| cord-000268-480d3yfv | a new player in acute inflammatory responses TREM-1 amplifies inflammation and is a crucial mediator of septic shock Does soluble triggering receptor expressed on myeloid cells-1 play any role in the pathogenesis of septic shock? |
| cord-024631-yvek5vjz | Clinically Useful in Today's Molecular Diagnostics World? |
| cord-024631-yvek5vjz | Why should we measure bacterial load when treating community- acquired pneumonia? |
| cord-297138-t8b3914h | Duration of symptoms was assessed as the number of days from enrollment, before the participant reported"Not sick"to the question"How sick do you feel today?" |
| cord-280629-vb0002nx | A prospective study of daily measurement of C- reactive protein in serum of adults with neutropenia Levels of C- reactive protein in patients with hematologic malignancies C reactive protein rapid assay techniques for monitoring resolution of infection in immunosuppressed patients Interleukin-6 and its relationship to C- reactive protein and fever in children with febrile neutropenia Acute phase reactants and risk of bacterial meningitis among febrile infants and children Usefulness of procalcitonin and C- reactive protein rapid tests for the management of children with urinary tract infection C- reactive protein in febrile children 1 to 36 months of age with clinically undetectable serious bacterial infection Systemic inflammatory response syndrome in the trauma intensive care unit: who is infected? |
| cord-297093-ld89vmct | Clinical and translational science Pharmacokinetics of anakinra in subjects with different levels of renal function Is the HScore useful in COVID-19? |
| cord-347014-88zmtky7 | results from the German Competence Network CAPNETZ Is mid- regional pro- atrial natriuretic peptide( MRproANP) an accurate marker of bacteremia in pyelonephritis? |
| cord-348053-s0ijzyaq | a prospective observational study Is a"Cytokine Storm"Relevant to COVID-19? |
| cord-023157-0lqlx2rv | In this study the answer to"Which is a better indicator for diabetes screening; BMI or waist circumference?"has been questioned. |
| cord-330411-hg1cxcs7 | the Central Nervous System Be Fogged by the Cytokine Storm in COVID-19?: |
| cord-343986-mneil7gn | What is the best therapy for influenza and other viral causes of community- acquired pneumonia? |
| cord-343986-mneil7gn | What is the real role of respiratory viruses in severe community- acquired pneumonia? |
| cord-343986-mneil7gn | a systematic review and meta- analysis Pneumonia study group: bacterial and viral etiology in hospitalized community acquired pneumonia with molecular methods and clinical evaluation What is the role of respiratory viruses in community- acquired pneumonia?: |
| cord-005497-w81ysjf9 | ( 1) Are serum- S1P levels affected by cardiac surgery? |
| cord-005497-w81ysjf9 | ( 2) Are potential alterations of serum- S1P levels related to changes of acute- phase proteins, S1P sources or carrier? |
| cord-005497-w81ysjf9 | ( 3) Is the invasiveness of the surgery a factor that may influence serum- S1P levels? |
| cord-005497-w81ysjf9 | A hybrid approach as treatment for coronary artery disease: endo- CABG or PCI first, does it matter? |
| cord-005497-w81ysjf9 | Assessing the volume of blood taken for blood culture and culture positivitydo we need to take less blood? |
| cord-005497-w81ysjf9 | Does the endotoxin adsorption of PMX column saturate in 2 hours? |
| cord-005497-w81ysjf9 | What is the useful coagulation and fibrinolysis marker for predicting extracorporeal membrane oxygenation circuit exchange due to intra- circuit thrombus? |
| cord-005727-li8pwigg | ; Hospital readmission within one- year? |
| cord-005727-li8pwigg | AND/ OR CRP HELP IDENTIFY ASSOCIATED BACTERIAL INFECTION IN PATIENTS WITH INFLUENZA PNEUMONIA? |
| cord-005727-li8pwigg | After what duration of onset of AF you consider starting anticoagulation? |
| cord-005727-li8pwigg | Are you aware of any guidelines? |
| cord-005727-li8pwigg | Do you commence anti platelet therapy? |
| cord-005727-li8pwigg | Do you commence anticoagulation for acute onset AF? |
| cord-005727-li8pwigg | How long do you continue anticoagulation? |
| cord-005727-li8pwigg | If yes, which guidelines? |
| cord-005727-li8pwigg | It could be that APACHE II is over estimating the severity of illness in these individuals, or is there something about the way chronic AF is treated that affects the response to critical illness, for example, anticoagulation therapy? |
| cord-005727-li8pwigg | Next, participants were asked to explore the questions'How do you learn the mentioned items?' |
| cord-005727-li8pwigg | Should the use of video laryngoscopy be implemented as a routine for airway management in a critical care setting? |
| cord-005727-li8pwigg | So, what is lost in translation? |
| cord-005727-li8pwigg | Taurine and niacin block lung injury and fibrosis by down- regulating bleomycin- induced activation of transcription nuclear factor- kappaB in mice Antioxidants and sepsis: Can we find the ideal approach? |
| cord-005727-li8pwigg | The questions asked were; is there a protocol in your unit? |
| cord-005727-li8pwigg | What do you use for anticoagulation and in what dose? |
| cord-005727-li8pwigg | When is HIT really HIT? |
| cord-005727-li8pwigg | and'What ways of learning do you find useful or superfluous?' |
| cord-005727-li8pwigg | predict: One- year all- cause mortality in ACS? |
| cord-005727-li8pwigg | should we use? |
| cord-015324-y44sfr0c | Can postnatal US diagnose significant PNU? |
| cord-015324-y44sfr0c | Crescentic Glomerulonephritis with Isolated C3 Deposits Associated to Complement Abnormalities: a New Entity? |
| cord-015324-y44sfr0c | Does ANH predict renal tract pathology in neonates? |
| cord-015324-y44sfr0c | Does sonographic quantification of the renal parenchyma allow estimation of isotopic renal function? |
| cord-015324-y44sfr0c | Drug Intake in the Background of Sudden Death? |
| cord-015324-y44sfr0c | Following Halothane Anesthesia in Young Child? |
| cord-015324-y44sfr0c | Generation of Oxidized Lipoproteins in Obstructive Nephropathy-Atherogenic or Fibrogenic? |
| cord-015324-y44sfr0c | How many neonates with ANH would need to be investigated to prevent one case of ESRF/ CRF? |
| cord-015324-y44sfr0c | How much Iron is Needed and how much is Toxic? |
| cord-015324-y44sfr0c | In order to improve long term outcome of these patients, increased awareness and an European( International?) |
| cord-015324-y44sfr0c | Is Repeated Urine Culture Essential after Antibiotic Therapy in UTI in Thai Children? |
| cord-015324-y44sfr0c | Is there a Role for Bisphosphonates in Pediatric Bone Disease? |
| cord-015324-y44sfr0c | Nephronophthisis and Joubert Syndrome: Converging on Convergent Extension? |
| cord-015324-y44sfr0c | Unilateral Renal Agenesis( URA): how Intensively do we Need to Investigate and Follow- up? |
| cord-015324-y44sfr0c | What exactly happened during arteriography in her left kidney, in order to provoke such ischemic injury, knowing that the left renal artery was not catheterized during arteriography and PTA? |
| cord-015324-y44sfr0c | What is the value of prophylactic antibiotics in infants with ANH? |
| cord-015324-y44sfr0c | When is the optimal time to screen infants postnatally? |
| cord-015324-y44sfr0c | Which Immunosuppression in Pediatric Transplantation? |
| cord-015324-y44sfr0c | Which imaging modalities are necessary to diagnose the cause of the HN? |
| cord-015021-pol2qm74 | ( 3) Should future clinical trials be based on new classifications of illness such as MODS, SIRS, APACHE III, SAP II, MRM, etc., or should trials be dedicated to specific diseases-urinary tract infections, pneumonia, trauma patients, cardiac surgery and other specific problems, rather than generalized problems of sepsis, the sepsis syndrome and other classifications? |
| cord-015021-pol2qm74 | 3-Is the ACCP classification of sepsis useful at the bedside to select oatients? |
| cord-015021-pol2qm74 | Abnormally high skeletal muscle pO 2 in septic patients and its normalization during recovery: Evidence against tissue hypoxia but for impaired oxygen metabolism of skeletal muscle? |
| cord-015021-pol2qm74 | Administration of exogenous IFN? |
| cord-015021-pol2qm74 | And, finally, how can the participants be sure that the trial will be stopped at the right time, to ensure that no treatment is given to any patient that might be harmful? |
| cord-015021-pol2qm74 | Are all eligible patients being studied, and their results reported? |
| cord-015021-pol2qm74 | Are all the participants truly unbiased about the relative merits of the regimens being studied? |
| cord-015021-pol2qm74 | Before using the model for risk of death in septic patients, is it mandatory to validate it( by calibration, i.e. goodness of fit, and discrin'dnation, i.e., ROC curves) first on a data base using the same definition for sepsis as in the trial and secondly on the placebo group of the trial? |
| cord-015021-pol2qm74 | Can it achives a significant improvement in the septic course, organ dysfunction, and final outcome? |
| cord-015021-pol2qm74 | Conversely, administration of anti- IFN? |
| cord-015021-pol2qm74 | Correlatively the RNI inhibitor MMLA induces in vitro a decrease in the rate of bacterial killing, fxom 78% to 57%, in macrophages triggered with IFN-?+ LPS. |
| cord-015021-pol2qm74 | How can organ dysfunction and/or failure be defined? |
| cord-015021-pol2qm74 | How should we decide which of them should be brought to clinical trial? |
| cord-015021-pol2qm74 | If there is agreement that thin is an appropriate antibiotic protocol, should it not be used in all seriously ill septic patients in the hospital? |
| cord-015021-pol2qm74 | In contrast, GF109203X significantly reduced ICAM-1 expression induced by Interferon- y( IFN-?) |
| cord-015021-pol2qm74 | In fact, the IFN-? and IL-1 induced adhesion of PBMC to cytokine treated HUVEC could be downregulated by the PKC- inhibitor, whereas TNFc~-and LPS- mediated adhesion was not influenced. |
| cord-015021-pol2qm74 | In other words, should we now begin to have clinical trials on specific diseases with causes that are known and can be attacked? |
| cord-015021-pol2qm74 | Interferon-? |
| cord-015021-pol2qm74 | Is like being compared with like-are all the end points and the standards for measuring them clearly defined so that they can not be misunderstood? |
| cord-015021-pol2qm74 | Is there any role for antioxidative therapy in sepsis? |
| cord-015021-pol2qm74 | Is truly informed consent being sought that will satisfy not only the patient's right to choose what happens to him, but also the law of the land? |
| cord-015021-pol2qm74 | MIF secretion also was induced by TNFoc( 1 ng/ ml) and IFN? |
| cord-015021-pol2qm74 | MIF secretion is induced by LPS, TNFc~ and IFN?. |
| cord-015021-pol2qm74 | Macrophages of C57BL/10ScCr mice are incapable of producing interferon-~( IFN~) which we could show to be obligatory for the production of IFN? |
| cord-015021-pol2qm74 | On closer investigation the impaired IFN? |
| cord-015021-pol2qm74 | The IFN? |
| cord-015021-pol2qm74 | The absence of sensitization to LPS in Lps d C57BL/10ScCr mice was identified as being due to their inability to produce interferon-7( IFN?). |
| cord-015021-pol2qm74 | The clinical"take"rate o? cultured epithelial autografts( CEA) has been observed to Increase with transplantation to allodermls, but the reasons for the improved clinical performance have not yet been defined. |
| cord-015021-pol2qm74 | The inability to produce adequate amounts of IL-2, most likely attributable to alterations in the transmission of signals from the cell membrane to the nucleus, results in incomplete proliferative T- cell responses to antigenic stimuli, while a lack of? |
| cord-015021-pol2qm74 | There are reports of nentrophil dysfunction in inflammatory disorders of the skin( 2), Are there dysfunctions concerning the unspecific host defense in SIRS, as well? |
| cord-015021-pol2qm74 | This has not happened, however, and the question is"Why not"? |
| cord-015021-pol2qm74 | This might be due to a preexisting( genetic?) or more likely to an epiphenomenal receptor defect. |
| cord-015021-pol2qm74 | We have investigated the proinflaznmatory oytokine secretion patter~ by PMN in patients following major~hermal or tra~ matic injury and in volunteers fellowinq endotoxemia.? |
| cord-015021-pol2qm74 | What are the definitions? |
| cord-015021-pol2qm74 | What are the issues, then, in 1994, to be dealt with at this symposium and congress? |
| cord-015021-pol2qm74 | What are the mechanisms? |
| cord-015021-pol2qm74 | What is the aplpiieability of study results in typical clinical situations? |
| cord-015021-pol2qm74 | What is the availability of speciftc antibiotics at a participating hospital? |
| cord-015021-pol2qm74 | Will the patient's physicians agree to the protocol choice? |
| cord-015021-pol2qm74 | Will they be helpful in the study and esro of patients? |
| cord-015021-pol2qm74 | Will this contribute to better clinical trials, information basis and better research? |
| cord-015021-pol2qm74 | Will we benefit Oleo from a more precise classification and definition of a non- outjty, a hodgu- podge of human disorders which have charsmeristic.s and manifestations of tissue injury, inflammation and infactian? |
| cord-015021-pol2qm74 | and?-IFN and T- helper-2( Th2) acting principally in inducing antibody formation with a secretion of IL-4, IL-5, IL-10 and TNF-[3 has still to be established within the context of major trauma. |
| cord-015021-pol2qm74 | anti- IFN-?( p<0.05). |
| cord-015021-pol2qm74 | or is it better to use a specific model for each trial? |
| cord-015021-pol2qm74 | ~is s?. |