trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram	frequency
as well as	1014
the treatment of	933
the use of	739
in patients with	721
for the treatment	563
the development of	554
in order to	466
the presence of	465
one of the	463
the number of	419
of the drug	407
due to the	397
based on the	397
background and objective	367
in the treatment	327
it has been	308
the role of	290
main outcome measures	278
can be used	272
in addition to	257
the effect of	255
specify your abstract	254
please specify your	254
your abstract type	254
or case report	241
purpose or case	241
the effects of	238
severe acute respiratory	235
the management of	229
acute respiratory syndrome	228
the risk of	217
a number of	216
of this study	212
be used to	210
an increase in	209
a variety of	208
treatment of covid	204
there is a	203
the aim of	201
in vitro and	200
for treatment of	199
respiratory syndrome coronavirus	199
in combination with	198
according to the	197
times a day	196
of patients with	195
and in vivo	191
on the other	189
in this study	188
a total of	187
the most common	184
as a result	183
used in the	182
food and drug	182
compared to the	181
and drug administration	179
the impact of	179
found to be	177
the other hand	176
of the patients	176
been shown to	175
vitro and in	175
such as the	173
increase in the	170
was used to	166
that can be	166
of the most	165
setting and method	165
in the presence	163
has also been	162
has been shown	161
hepatitis c virus	160
has been reported	158
the efficacy of	157
the case of	156
part of the	155
in terms of	155
study was to	155
well as the	153
the absence of	152
is associated with	151
of the drugs	151
abstract background and	150
have also been	150
research abstract background	150
drug delivery systems	149
the formation of	149
there is no	148
associated with the	148
to evaluate the	148
the need for	147
mechanism of action	146
have been reported	146
most of the	145
involved in the	143
a result of	143
some of the	143
a review of	139
role in the	139
the discovery of	138
in response to	136
related to the	135
of these drugs	133
in the case	132
the purpose of	132
to be a	132
to improve the	131
was found to	130
can also be	130
be used for	129
in the absence	128
the results of	127
drug delivery system	126
with respect to	126
of the disease	125
the importance of	124
patients with covid	124
is one of	124
to determine the	124
have been used	123
the united states	122
p r e	121
p r o	121
n a l	120
o o f	120
r n a	120
u r n	120
structure of the	120
o u r	120
l p r	120
is the most	120
j o u	120
this study was	120
r o o	120
a l p	120
review of the	119
the lack of	119
need to be	117
used for the	116
to assess the	116
it can be	116
used to treat	116
in the lungs	116
because of the	115
found in the	115
analysis of the	114
used as a	113
aim of this	113
chloroquine and hydroxychloroquine	113
have shown that	112
which can be	112
the fact that	112
world health organization	111
the expression of	110
it is important	110
is important to	110
to reduce the	109
the activity of	109
the potential to	109
of the virus	109
the majority of	109
for drug delivery	109
due to its	108
the identification of	108
the administration of	107
a systematic review	107
the process of	106
to investigate the	106
the field of	106
in the united	105
the effectiveness of	105
toxic epidermal necrolysis	105
the delivery of	105
as compared to	104
in drug discovery	103
the level of	103
and safety of	102
in the development	102
the incidence of	102
in the rat	101
twice a day	100
has not been	100
a combination of	100
at least one	100
understanding of the	99
responsible for the	99
of the human	99
associated with a	99
drug discovery and	99
included in the	98
e times a	98
of action of	98
wide range of	97
efficacy and safety	97
be used as	97
the context of	97
the influence of	97
east respiratory syndrome	97
been reported to	96
in the field	96
the mechanism of	96
the basis of	96
middle east respiratory	95
evaluation of the	95
an important role	94
and in the	94
human immunodeficiency virus	94
the design of	94
changes in the	94
adverse drug reactions	94
patients treated with	93
of the study	93
the application of	93
due to their	93
a range of	93
in the context	92
in case of	92
the production of	92
in the human	92
important role in	91
are associated with	91
for the management	91
can lead to	91
the release of	90
and treatment of	90
has been used	90
a wide range	90
as a potential	90
depending on the	90
the quality of	90
amino acid composition	90
there was no	89
antiviral activity of	89
shown to be	89
in contrast to	89
to be the	88
of a drug	88
a series of	88
the evaluation of	88
is based on	88
been used to	87
in the lung	87
and can be	87
the amount of	87
this study is	87
the end of	87
study is to	87
the course of	87
in clinical trials	86
use of a	86
the most important	85
for patients with	85
it is not	85
once a day	85
for the development	84
in the first	84
was carried out	84
the combination of	84
as part of	84
the diagnosis of	84
in the same	84
purpose of this	84
the ability to	84
were used to	84
on the basis	83
the surface of	83
in the management	83
diseases such as	83
effects of the	83
be associated with	82
study of the	82
at the same	82
based on a	82
the frequency of	82
in the past	82
the interaction of	82
which is a	82
it should be	82
shown in figure	81
of the sars	81
addition to the	81
of the lung	80
in the liver	80
were found to	80
should be considered	80
patients with severe	80
inhibition of the	80
appears to be	80
the present study	80
be used in	80
the potential of	79
may also be	78
adsorption energy of	78
to identify the	78
it is a	77
been reported in	77
epidermal growth factor	77
the inhibition of	77
is necessary to	76
to study the	76
and in vitro	76
in the study	76
the drug is	76
quality of life	75
was associated with	75
central nervous system	75
for drug discovery	75
the small intestine	75
the binding of	75
development of a	75
in which the	75
cells in the	74
could be used	74
the active site	74
have been developed	74
that have been	74
it is also	74
effect on the	74
each of the	74
in the literature	74
discovery and development	73
is an important	73
drugs have been	72
respiratory distress syndrome	72
the prevalence of	72
drugs such as	72
with regard to	72
in accordance with	72
activity of the	72
crystal structure of	72
as shown in	72
the main protease	72
the possibility of	71
of severe acute	71
present in the	71
use of the	70
in the last	70
the same time	70
granted medrxiv a	69
studies have shown	69
approved by the	69
the range of	69
display the preprint	69
needs to be	69
who has granted	69
to be effective	69
the ability of	69
to display the	69
preprint in perpetuity	69
large number of	69
license to display	69
a license to	69
in the stomach	69
pseudo amino acid	69
the gastrointestinal tract	69
the preprint in	69
medrxiv a license	69
has granted medrxiv	69
and characterization of	68
the pathogenesis of	68
the in vitro	68
drugs in the	68
is used to	68
targeted delivery of	68
influenza a virus	68
some of these	67
the rate of	67
a and b	67
in a patient	67
in cases of	67
dependent rna polymerase	67
guidelines for the	67
to be used	67
it is possible	67
for the first	67
and it is	66
been associated with	66
the objective of	66
decrease in the	66
that has been	66
observed in the	66
may lead to	66
are the most	66
contribute to the	65
the onset of	65
the study of	65
a period of	65
the degree of	65
acute respiratory distress	65
the severity of	65
over the past	65
the world health	65
caused by the	65
the structure of	64
a decrease in	64
combination therapy with	64
the type of	64
l energy gap	64
the detection of	64
the proportion of	64
in the pediatric	64
led to the	64
likely to be	63
is that the	63
the synthesis of	63
the addition of	63
in the small	63
there are no	63
the novel coronavirus	63
of novel coronavirus	63
the time of	63
should be selected	63
well as in	63
of the protein	63
of drugs and	63
the pharmaceutical industry	62
the extent of	62
a patient with	62
targeted drug delivery	62
in the us	62
in comparison to	62
of a new	62
is a major	62
the analysis of	62
in the number	62
half of the	62
the duration of	62
the copyright holder	62
in the s	62
a set of	61
a role in	61
can be found	61
was observed in	61
copyright holder for	61
holder for this	61
in this case	61
adverse effects of	61
out of the	61
for this preprint	61
in some cases	61
are able to	61
in recent years	61
results of the	60
in the future	60
was used for	60
increased risk of	60
reported in the	60
has to be	60
size of the	60
the pharmacokinetics of	60
drugs should be	60
mechanisms of action	59
in the early	59
of the total	59
that there is	59
the prevention of	59
more than one	59
the immune system	59
properties of the	59
an overview of	59
in this review	59
the size of	59
objective of this	59
showed that the	59
of chloroquine and	59
drugs to be	59
morbidity and mortality	59
total number of	59
also be used	58
intensive care unit	58
aim of the	58
effect of the	58
g e times	58
end of the	58
along with the	58
in relation to	58
are needed to	58
compared with the	58
been used in	58
may be a	58
the activation of	58
the relationship between	58
that could be	58
mode of action	58
the study was	58
on the surface	58
growth factor receptor	58
are shown in	58
to treat covid	58
for the delivery	57
of the viral	57
seems to be	57
which may be	57
the concept of	57
may not be	57
differences in the	57
years of age	57
many of the	57
nature of the	57
be able to	57
of infectious diseases	57
derived from the	57
parts of the	57
was shown to	56
is responsible for	56
to increase the	56
different types of	56
of cyp a	56
inhibitors of the	56
at the time	56
which was not	56
in cell culture	56
critically ill patients	56
the action of	56
the concentration of	56
mg twice a	56
the assessment of	56
in children with	56
has been suggested	56
leading to the	56
it may be	56
for use in	56
in a study	56
with the use	56
assessment of the	56
of hepatitis c	55
were included in	55
shown that the	55
the most commonly	55
of the clinical	55
side effects of	55
depends on the	55
to understand the	55
known to be	55
by the fda	55
at the end	55
that of the	55
to have a	55
are used to	55
the form of	55
the need to	55
more than of	55
because of its	55
is essential for	54
also known as	54
the performance of	54
similar to the	54
be found in	54
cells of the	54
to the development	54
in the body	54
we found that	54
to develop a	54
the drug and	54
they can be	54
of a novel	54
in many cases	54
a list of	54
patients with a	54
is known to	54
the introduction of	53
diagnosis and treatment	53
may result in	53
all rights reserved	53
has been demonstrated	53
drug repurposing for	53
a large number	53
when compared with	53
in the blood	53
binding free energy	53
drug delivery and	53
been used for	53
stability of the	53
been found to	53
were treated with	53
were able to	52
safety and efficacy	52
a lack of	52
the cost of	52
hepatitis b virus	52
of the patient	52
kg times a	52
due to a	52
as high as	52
effects on the	52
and development of	52
patients with chronic	52
to the drug	52
there is an	52
herpes simplex virus	52
of the literature	52
has the potential	52
reported to be	52
mg kg times	52
it is necessary	52
number of patients	52
the result of	52
the growth of	51
breast cancer cells	51
the leading edge	51
role of the	51
have to be	51
magnetic resonance imaging	51
in this context	51
are responsible for	51
there was a	51
prevention and treatment	51
in a recent	51
surface of the	51
are known to	51
risk factors for	51
resulted in a	51
the stability of	51
fda approved drugs	51
widely used in	51
in the form	51
in drug delivery	51
to enhance the	51
was used as	50
is defined as	50
have been described	50
is able to	50
systematic review of	50
development of the	50
the most frequent	50
in treatment of	50
has been found	50
when compared to	50
the value of	50
activation of the	50
of drug resistance	50
by means of	50
this is a	50
of the rat	50
have been shown	50
the efficacy and	50
treatment of severe	50
cell lung cancer	50
the respiratory tract	50
of the main	50
reduction in the	50
in the current	49
to inhibit the	49
solid lipid nanoparticles	49
the potential for	49
similar to those	49
tumor necrosis factor	49
should not be	49
of the target	49
of clinical trials	49
this type of	49
should be used	49
been shown that	49
there are many	49
with severe covid	49
function of the	49
in the following	48
lung cancer cells	48
as a drug	48
the induction of	48
in association with	48
efficacy of the	48
with or without	48
of the channel	48
is characterized by	48
before and after	48
the adsorption of	48
of cytochrome p	48
of antimicrobial drugs	48
of the cases	48
been widely used	48
information about the	48
of the small	48
characterization of the	48
obtained from the	47
are involved in	47
pulmonary drug delivery	47
there has been	47
have the potential	47
a study of	47
lead to the	47
a group of	47
which has been	47
of more than	47
found that the	47
in of the	47
more likely to	47
chronic hepatitis c	47
dose of mg	47
to examine the	47
development of new	47
the site of	47
the total number	47
led to a	47
recent advances in	47
a recent study	47
appear to be	47
an inhibitor of	47
the host cell	47
systemic lupus erythematosus	47
have not been	47
been suggested that	47
the function of	47
in laboratory animals	47
the safety of	47
of coronavirus disease	46
of this drug	46
as in the	46
to provide a	46
in vivo studies	46
change in the	46
there have been	46
drugs for the	46
their ability to	46
the food and	46
was able to	46
by the presence	46
clinical trials for	46
an in vitro	46
in drug design	46
should be performed	46
the emergence of	46
will be discussed	46
of influenza a	46
of the treatment	46
supported by the	46
wide variety of	46
the involvement of	46
the selection of	46
the regulation of	45
treatment of patients	45
response to the	45
the replication of	45
antiviral activity against	45
described in the	45
for the prevention	45
is related to	45
are required to	45
impact of the	45
to that of	45
in the range	45
study on the	45
of the first	45
a wide variety	45
the nature of	45
all of the	45
as a consequence	45
and efficacy of	45
with an increase	44
presence of a	44
presence of the	44
that it is	44
have been identified	44
the progression of	44
and cyp a	44
the distribution of	44
based on their	44
knowledge of the	44
of all the	44
lead to a	44
referred to as	44
because of their	44
followed by a	44
a history of	44
use in the	44
for drug repurposing	44
or in combination	44
a case report	44
cancer stem cells	44
in our hospital	44
resulting in a	44
there are several	44
is caused by	44
in a mouse	44
impact on the	44
the drug in	44
the setting of	44
prior to the	44
of these patients	44
head and neck	44
it has also	43
to be recommended	43
shown in fig	43
respiratory syncytial virus	43
could not be	43
the in vivo	43
used to identify	43
were used as	43
the immune response	43
has been proposed	43
reactive oxygen species	43
is the first	43
delivery system for	43
for breast cancer	43
the success of	43
also been used	43
be combined with	43
is also a	43
can be achieved	43
mg kg day	43
of the ligand	43
be related to	43
is not a	43
this can be	43
chronic obstructive pulmonary	42
the first time	42
inflammatory bowel disease	42
to be associated	42
be due to	42
based drug design	42
the antiviral activity	42
located in the	42
is shown in	42
members of the	42
is likely to	42
of the lungs	42
are likely to	42
and drug delivery	42
an example of	42
is difficult to	42
have been proposed	42
the human body	42
should also be	42
the appearance of	42
a reduction in	42
one or more	42
administration of the	42
in the setting	42
the search for	42
to predict the	42
obstructive pulmonary disease	42
of lung cancer	42
in our study	42
a mouse model	42
leading edge pseudopod	42
are found in	42
in this regard	42
the binding site	42
provided by the	42
the plasma membrane	42
in vitro studies	42
than in the	41
be involved in	41
to reach the	41
member of the	41
effects of chloroquine	41
based drug discovery	41
of drug delivery	41
with and without	41
to be an	41
drugs for covid	41
during the covid	41
of the two	41
of side effects	41
in clinical practice	41
high levels of	41
conflict of interest	41
information on the	41
this is the	41
in vivo and	41
treatment of the	41
treatment of sars	41
oral delivery of	41
results of a	41
of cancer cells	40
it was found	40
with an adsorption	40
metastatic breast cancer	40
must be considered	40
the availability of	40
volume of distribution	40
the side effects	40
an adsorption energy	40
can be seen	40
in vitro antiviral	40
use of these	40
there were no	40
van der waals	40
hcq and cq	40
in the community	40
could be a	40
the control of	40
study showed that	40
to the lungs	40
interaction with the	40
suggested that the	40
should be avoided	40
of breast cancer	40
the clinical pharmacist	40
the last years	40
dose activated charcoal	40
for cancer therapy	40
in the pathogenesis	40
clinical trials are	40
than that of	40
randomized clinical trial	40
patients were included	40
will be presented	40
results suggest that	39
of drugs that	39
of the same	39
of drug discovery	39
revealed that the	39
delivery of drugs	39
it was observed	39
the past years	39
delivery to the	39
factors such as	39
allowed without permission	39
a crucial role	39
of cyp c	39
in the clinic	39
to describe the	39
the authors declare	39
considered to be	39
study was conducted	39
was found in	39
in this work	39
have been found	39
in the drug	39
respect to the	39
the most promising	39
for up to	39
over the last	39
these drugs are	39
in the clinical	39
no reuse allowed	39
reuse allowed without	39
also been reported	39
the university of	39
release of the	39
rats treated with	39
focused on the	39
expression of the	39
in animal models	39
combination with other	39
the drug was	39
on the use	39
with a high	39
of in vitro	39
hydroxychloroquine and chloroquine	39
activity in the	38
is due to	38
to ensure that	38
insights into the	38
two or more	38
by using the	38
to be more	38
patients infected with	38
clinical characteristics of	38
acute lung injury	38
drugs that are	38
the lymphatic system	38
this drug is	38
in the evaluation	38
a dose of	38
drug should be	38
portion of the	38
and management of	38
is possible to	38
of the skin	38
should be administered	38
in the present	38
the last decade	38
it was shown	38
serve as a	38
virtual screening of	38
which is the	38
as a treatment	38
well as a	38
advantage of the	38
be considered in	38
and toxic epidermal	37
with the aim	37
mouse model of	37
were observed in	37
new york city	37
by the food	37
it is the	37
the adsorption energy	37
for drug repositioning	37
of the active	37
of the four	37
drug delivery in	37
in the elderly	37
mechanism of the	37
similar to that	37
there may be	37
alone or in	37
may be used	37
of health and	37
in the upper	37
an average of	37
in the h	37
low molecular weight	37
the occurrence of	37
used as the	37
kcal mol for	37
the generation of	37
characteristics of the	37
of the body	37
hyperplasia of the	37
be noted that	37
none of the	37
small cell lung	37
were obtained from	37
the age of	37
dependent on the	37
was to evaluate	37
is a common	37
a function of	37
in breast cancer	36
that are not	36
play a role	36
was not peer	36
its ability to	36
components of the	36
and use of	36
of the m	36
of drugs with	36
as a model	36
for the diagnosis	36
for more than	36
the metabolism of	36
the pediatric population	36
site of the	36
has led to	36
molecular dynamics simulation	36
the interaction between	36
was observed that	36
in of cases	36
of the respiratory	36
nuclear magnetic resonance	36
diffuse alveolar damage	36
of a single	36
the usefulness of	36
the reduction of	36
is required for	36
and of the	36
suggest that the	36
inhibitors of sars	36
drug delivery to	36
part of a	36
patients in the	36
kcal mol with	36
of the three	36
research and development	36
duration of the	36
the goal of	36
case of the	36
to measure the	35
can be a	35
expressed in the	35
total of patients	35
in the process	35
with a maximum	35
taken into account	35
during the first	35
of drug repurposing	35
the needs of	35
that the drug	35
to explore the	35
and evaluation of	35
of the world	35
the contribution of	35
proteins in the	35
in silico pharmacology	35
bind to the	35
the emergency department	35
play an important	35
particularly in the	35
to the use	35
higher risk of	35
resulted in the	35
the choice of	35
reported that the	35
is involved in	35
between the two	35
in cancer therapy	35
angiotensin converting enzyme	35
is a key	35
the implementation of	35
performance of the	35
consistent with the	35
the start of	35
with the highest	35
attributed to the	35
number of drugs	34
is essential to	34
a clinical pharmacist	34
were associated with	34
of antiviral drugs	34
was performed using	34
respiratory infectious diseases	34
the preparation of	34
in most cases	34
the spread of	34
it is worth	34
for evaluation of	34
risk factor for	34
which have been	34
interaction between the	34
which in turn	34
based virtual screening	34
the lungs of	34
should be noted	34
of the covid	34
of activated charcoal	34
is mediated by	34
for each drug	34
action of the	34
drugs can be	34
of the new	34
the mechanisms of	34
not associated with	34
is expected to	34
many of these	34
be effective against	34
cancer cell lines	34
in this section	34
that may be	34
affected by the	34
was found that	34
severity of the	34
in pediatric patients	34
a case of	34
are based on	34
the advantage of	34
conditions such as	34
the uptake of	34
in the brain	34
treatment of chronic	34
hydroxychloroquine and azithromycin	34
and has been	34
binding of the	34
has indicated that	34
drugs that can	33
has been widely	33
to an increase	33
was based on	33
cases in which	33
in comparison with	33
in the plasma	33
the increase in	33
is required to	33
interstitial lung disease	33
the relevance of	33
thought to be	33
cyp a and	33
of a protein	33
yet to be	33
both in vitro	33
use of this	33
sensitivity and specificity	33
drug sales data	33
in the hospital	33
in rats and	33
were found in	33
the list of	33
a broad spectrum	33
treatment of acute	33
in the tumor	33
entry into the	33
of the present	33
results in a	33
to be considered	33
it is difficult	33
have already been	33
the results were	33
who inject drugs	33
the beginning of	33
associated with an	33
around the world	33
patients with the	33
of the current	33
for delivery of	33
in silico drug	33
the sensitivity of	33
health care system	33
no conflict of	33
of the binding	33
our understanding of	33
treated with the	33
a new drug	33
has been observed	33
in hospitalized patients	33
of action and	33
of clinical pharmacy	33
the efficiency of	33
of the proposed	33
in the world	33
has been described	33
identification of potential	32
and the development	32
of the major	32
of these compounds	32
of our study	32
the existence of	32
we aimed to	32
for the identification	32
from patients with	32
a critical role	32
the complexity of	32
data were collected	32
damage to the	32
a clinical trial	32
the drug delivery	32
in new york	32
the guidelines for	32
control of the	32
insight into the	32
structure of sars	32
of small molecules	32
is used in	32
cov and mers	32
the most frequently	32
the prediction of	32
side effects and	32
a novel coronavirus	32
of the cell	32
therapeutic efficacy of	32
of the population	32
of drugs in	32
found to have	32
but not in	32
a consequence of	32
has been associated	32
be considered as	32
to analyse the	32
mg once a	32
to overcome the	32
comparison of the	32
the general population	32
drugs to the	32
period of time	32
may be required	32
oral administration of	32
antimicrobial drugs should	32
of resistant bacteria	32
focus on the	32
there are two	32
in patients who	32
have been widely	32
isolated from the	32
into the cell	32
human serum albumin	32
involvement of the	32
data from the	31
the health of	31
with the drug	31
result in a	31
in all cases	31
most of these	31
used in combination	31
because it is	31
in the control	31
demonstrated that the	31
for drug development	31
syndrome and toxic	31
also been shown	31
with a new	31
as a new	31
state of the	31
was not certified	31
not certified by	31
for the detection	31
antimicrobial drug therapy	31
its use in	31
by peer review	31
has been a	31
further studies are	31
was observed as	31
for the drug	31
to the target	31
which could be	31
results showed that	31
to identify potential	31
interfere with the	31
available in the	31
patients with acute	31
over a period	31
of anticancer drugs	31
to address the	31
of viral infections	31
could also be	31
in those with	31
in the gastrointestinal	31
interactions with the	31
the accumulation of	31
orders of magnitude	31
is thought to	31
is the author	31
certified by peer	31
prevention and control	31
zika virus infection	31
majority of the	31
was to investigate	31
for this reason	31
a risk of	31
a member of	31
lesions in the	31
was determined by	31
and to the	31
the levels of	31
more than years	31
hospitalized patients with	31
the author funder	31
been used as	31
was shown that	31
plays an important	31
has recently been	31
to make a	31
contrast to the	31
of the different	31
binding site of	31
the diagnosis and	31
result of the	31
carried out in	31
as it is	31
was performed in	31
the lamina propria	31
of adverse effects	31
in the diagnosis	31
be useful for	31
relative to the	31
the percentage of	31
concentration of the	31
the control group	31
of up to	31
in spite of	31
studies on the	31
of which are	31
be effective in	30
johnson syndrome and	30
randomized controlled trial	30
a key role	30
to estimate the	30
infectious diseases in	30
expected to be	30
as soon as	30
chronic kidney disease	30
and may be	30
health and social	30
any of the	30
sars and mers	30
the length of	30
in another study	30
linked to the	30
in the cell	30
in patients treated	30
systematic review and	30
significant difference in	30
proved to be	30
component of the	30
in patients receiving	30
mutations in the	30
of adverse drug	30
familial mediterranean fever	30
the drug discovery	30
findings suggest that	30
was used in	30
of the whole	30
critical role in	30
seen in the	30
has shown that	30
regions of the	30
results indicate that	30
can be observed	30
and the drug	30
is a potent	30
occur in the	30
basis of the	30
accordance with the	30
can result in	30
to the same	30
used as an	30
was conducted in	30
are in the	30
it is an	30
potent inhibitor of	30
little or no	30
withdrawal of the	30
health care professionals	30
of the various	30
site of action	30
american college of	30
as a novel	30
they are not	30
better understanding of	30
so that the	30
difference in the	30
view of the	30
a medical device	30
regulation of the	30
on the pharmacokinetics	30
cause of death	30
c virus infection	30
the lungs and	30
liu et al	30
and for the	30
is similar to	30
wang et al	30
is needed to	30
to the patient	30
traditional chinese medicine	30
the gastric mucosa	30
reduction of the	30
with the same	30
in the usa	29
discovery of new	29
leads to the	29
sustained release of	29
for disease control	29
mediated by the	29
of the compounds	29
have been studied	29
has resulted in	29
the spectrum of	29
the accuracy of	29
chen et al	29
important in the	29
active site of	29
the scope of	29
classified by the	29
of the gastric	29
in the design	29
amino acid residues	29
are characterized by	29
for the study	29
no significant difference	29
binding to the	29
and it has	29
for this purpose	29
this work was	29
and the use	29
a significant increase	29
followed by the	29
proven to be	29
of causative microorganisms	29
the need of	29
the central nervous	29
studies of the	29
a retrospective study	29
a lot of	29
were the most	29
be the most	29
a drug delivery	29
have been associated	29
the cause of	29
drug in the	29
agents such as	29
congenital heart disease	29
is composed of	29
course of the	29
protein data bank	29
are capable of	29
in view of	29
of a medical	29
imaging findings of	29
therapeutic options for	29
in a large	29
of the host	29
according to their	29
to compare the	29
of the coronavirus	29
has been the	29
present study was	29
to those of	29
the patient and	29
in a variety	29
high doses of	29
health care providers	29
are present in	29
the most effective	29
features of the	29
vitro antiviral activity	29
may be the	29
the entry of	29
will also be	29
and function of	29
is the only	29
we investigated the	28
results from the	28
have led to	28
residues in the	28
rats and mice	28
show that the	28
and discovery of	28
a pilot study	28
of health care	28
of the pediatric	28
discuss or describe	28
but also to	28
with at least	28
to better understand	28
most commonly used	28
is classified by	28
dna and rna	28
respiratory tract infection	28
to interact with	28
with the development	28
the public health	28
management of respiratory	28
shown in table	28
the association between	28
drug discovery process	28
the integration of	28
an anticancer drug	28
were used for	28
is widely used	28
human cell lines	28
seem to be	28
will discuss or	28
the first step	28
to treat the	28
of the test	28
with more than	28
li et al	28
potential inhibitors of	28
based on these	28
commonly used in	28
act as a	28
of middle east	28
in healthy volunteers	28
are similar to	28
the target cells	28
a mixture of	28
an increased risk	28
of hydroxychloroquine in	28
identification of the	28
are used for	28
to health care	28
drug design and	28
cancer cells and	28
all of these	28
in the mouse	28
be applied to	28
of this disease	28
the probability of	28
is dependent on	28
studies are needed	28
plasma protein binding	28
significant increase in	28
of lopinavir ritonavir	28
the dose of	28
approved for the	28
the drugs are	28
the safety and	28
this is an	28
are presented in	28
in cancer cells	28
there is also	28
is a promising	28
relationship between the	28
would like to	28
the chemical structure	28
at our institution	28
was approved by	28
and the number	28
clinical trials in	28
results show that	28
interact with the	28
but it is	28
on the market	28
is a well	28
of therapeutic agents	28
as a function	28
or absence of	28
acts as a	28
the understanding of	28
a public health	28
are listed in	28
high level of	28
resulting in the	28
of the potential	28
was reported in	28
been linked to	28
was the first	28
well as to	28
factors associated with	27
and its derivatives	27
in of patients	27
aspects of the	27
with rheumatoid arthritis	27
clinical trials and	27
is used for	27
added to the	27
or pharmaceutical that	27
depend on the	27
data on the	27
number of the	27
be included in	27
data suggest that	27
prediction of drug	27
mg kg once	27
one of these	27
and the presence	27
disease caused by	27
a need for	27
pharmaceutical that is	27
can be applied	27
and lack of	27
review and meta	27
device or pharmaceutical	27
drug related problems	27
that is classified	27
of drugs to	27
for in vivo	27
of the oral	27
with novel coronavirus	27
of new drugs	27
of hydroxychloroquine and	27
as a promising	27
investigational for intended	27
medical device or	27
retrospective review of	27
to the high	27
for biomedical applications	27
remdesivir and chloroquine	27
to deal with	27
be a promising	27
the outcome of	27
estimated to be	27
the amino acid	27
for the discovery	27
observed that the	27
the liver and	27
key role in	27
in the regulation	27
in the respiratory	27
and systemic symptoms	27
in drug development	27
in a similar	27
for targeted delivery	27
studies have been	27
the hypothesis that	27
the future of	27
for intended use	27
of drug repositioning	27
for the purpose	27
two of the	27
broad spectrum of	27
all over the	27
which there is	27
were collected from	27
iron oxide nanoparticles	27
of natural products	27
kcal mol and	27
considered as a	27
of the following	27
the cyp c	27
the focus of	27
lower respiratory tract	27
e g e	27
as investigational for	27
of this work	27
retrospective cohort study	27
limited number of	27
could lead to	27
effectively inhibit the	27
and that the	27
taking into account	27
drug targets and	27
the patients with	27
in the course	27
to prevent the	27
a use of	27
it would be	27
in the educational	27
were carried out	27
controlled drug delivery	27
the educational content	27
this is not	27
virtual screening and	27
in the second	27
with other drugs	27
delivery of the	27
respiratory tract infections	27
in the uk	26
for the covid	26
drugs used in	26
do not have	26
with eosinophilia and	26
as a possible	26
vascular endothelial growth	26
treatments for covid	26
a new coronavirus	26
early stages of	26
only a few	26
of in silico	26
mean age of	26
clinical features of	26
united states food	26
determined by the	26
idiopathic pulmonary fibrosis	26
cq and hcq	26
is the case	26
and side effects	26
in lung cancer	26
therapy should be	26
as compared with	26
will be used	26
the recently emerged	26
the gi tract	26
listed in table	26
due to an	26
identification of a	26
applied to the	26
x for peer	26
delivery systems for	26
the adverse effects	26
the severe acute	26
study reported that	26
characterized by a	26
the advent of	26
and it was	26
was reported to	26
duration of treatment	26
recently emerged novel	26
such as a	26
did not have	26
and should be	26
exposure to the	26
in rats treated	26
pneumonia in wuhan	26
chloroquine effectively inhibit	26
as they are	26
indicate that the	26
fold higher than	26
the oral cavity	26
of the enzyme	26
the target site	26
of the effects	26
belonging to the	26
authors declare no	26
innate immune response	26
upper respiratory tract	26
was to assess	26
there are also	26
in these patients	26
the results obtained	26
higher than that	26
the determination of	26
disruption of the	26
be responsible for	26
in elderly patients	26
marine natural products	26
for peer review	26
the drug release	26
various types of	26
the drug to	26
and duration of	26
and on the	26
to note that	26
which leads to	26
of this approach	26
and the other	26
been reported that	26
results in the	26
stages of the	26
eosinophilia and systemic	26
inhibit the recently	26
are used in	26
cd t cells	26
model of the	26
in clinical studies	26
of the above	26
of patients in	26
than of the	26
the period of	26
effects of drugs	26
peer review of	26
it was also	26
a drug that	26
patients who are	26
this article is	26
in this way	26
in line with	26
for many years	26
of patients were	26
endothelial growth factor	26
of the leading	26
group of patients	26
order to improve	26
acute and chronic	26
they do not	26
this approach is	25
was also observed	25
been carried out	25
patients who have	25
drugs to treat	25
characterized by the	25
chemical structure of	25
up to days	25
safe and effective	25
a better understanding	25
that there are	25
to ensure the	25
states food and	25
immune response to	25
refer to the	25
along with a	25
the association of	25
remains to be	25
significantly associated with	25
in the skin	25
to be involved	25
little is known	25
was performed by	25
leading cause of	25
the human interactome	25
intravenous injection or	25
in which there	25
are expected to	25
approach to the	25
a potent inhibitor	25
are summarized in	25
is important for	25
for at least	25
drug repositioning for	25
the cell surface	25
in this area	25
in hepatocellular carcinoma	25
the excess proton	25
have suggested that	25
the binding pocket	25
are necessary to	25
people who inject	25
correlated with the	25
structure of a	25
novel coronavirus in	25
controlled drug release	25
method for the	25
the strength of	25
drugs that have	25
were identified in	25
they are also	25
is a very	25
carried out by	25
development of an	25
has been studied	25
gene expression in	25
emerged novel coronavirus	25
molecular dynamics simulations	25
and in some	25
and there is	25
molecular mechanisms of	25
access to health	25
and pharmacokinetics of	25
the rest of	25
transforming growth factor	25
a retrospective review	25
which results in	25
were identified as	25
into account the	25
crucial role in	25
a subset of	25
appearance of the	25
and chloroquine effectively	25
e mg kg	25
of human immunodeficiency	25
drug development and	25
may have a	25
to identify and	25
injection or drip	25
and mechanism of	25
employed in the	25
acquired pneumonia in	25
and clinical trials	25
management of covid	25
in the next	25
modification of the	25
treatment for covid	25
drug release in	25
in silico screening	25
a spectrum of	25
may contribute to	25
at risk of	25
a single dose	25
in both the	25
fold increase in	25
be explained by	25
as an effective	25
increase the risk	25
its role in	25
the cell membrane	25
level of the	25
for a particular	25
is still a	25
examination of the	25
are caused by	25
presence or absence	25
during the study	25
no significant differences	25
a change in	25
as an anti	25
at least in	25
to quantify the	25
the health care	25
taken up by	25
although it is	25
even in the	25
the vast majority	25
shows that the	25
disease control and	25
the area of	25
the patients were	25
and review of	25
are related to	25
a diagnosis of	25
region of the	24
the incorporation of	24
of these two	24
ill patients with	24
controlled release of	24
of the novel	24
options for the	24
on the development	24
are composed of	24
of the therapeutic	24
of a large	24
plasma concentrations of	24
in the late	24
the development and	24
to establish a	24
has been approved	24
be attributed to	24
strategy for the	24
acute renal failure	24
example of a	24
kg once a	24
acute generalized exanthematous	24
of the data	24
in cystic fibrosis	24
suggests that the	24
viral replication and	24
objective was to	24
high concentrations of	24
rest of the	24
administration of a	24
in a dose	24
can be considered	24
a basis for	24
safety of the	24
the skin and	24
may be more	24
patients with renal	24
the therapy of	24
patients in whom	24
the patient is	24
is known about	24
of the mucosa	24
to minimize the	24
b and c	24
to our knowledge	24
are essential for	24
for the use	24
of the use	24
emergency use authorization	24
were subjected to	24
therapeutic drug monitoring	24
be carried out	24
the binding affinity	24
of patients who	24
no evidence of	24
bovine serum albumin	24
pi k akt	24
the history of	24
over the world	24
to test the	24
japanese respiratory society	24
is found in	24
inhibitor of the	24
the properties of	24
of at least	24
will focus on	24
quality of the	24
against the sars	24
and at the	24
a model of	24
the host cells	24
after administration of	24
who use drugs	24
in the area	24
in diseased tissues	24
significant reduction in	24
drug repurposing is	24
effect of colchicine	24
in rheumatoid arthritis	24
than half of	24
with an average	24
the benefit of	24
application of the	24
higher than in	24
defined as the	24
bound to the	24
us food and	24
it is likely	24
levels of the	24
up to of	24
this version posted	24
by inhibiting the	24
at the site	24
the crystal structure	24
the nasal cavity	24
cells in vitro	24
also be considered	24
and could be	24
is not clear	24
was applied to	24
as an example	24
between the drug	24
for the design	24
value of the	24
no effect on	24
of the antiviral	24
control and prevention	24
associated pneumonia in	24
owing to the	24
patients with rheumatoid	24
broad range of	24
at a dose	24
in critically ill	24
of respiratory infectious	24
in the lower	24
infections caused by	24
people who use	23
increases the risk	23
by the use	23
in a single	23
of ebola virus	23
concentrations of the	23
be taken into	23
was supported by	23
been described in	23
overview of the	23
identified in the	23
inhibitory effect of	23
of antiviral agents	23
the innate immune	23
been approved for	23
as low as	23
identified as a	23
the difference in	23
the drug development	23
the interactions between	23
resistance to the	23
the past decade	23
and frequency of	23
in this population	23
in human plasma	23
to the discovery	23
the disease and	23
can serve as	23
discovery of novel	23
by the same	23
distribution of the	23
in the use	23
de novo drug	23
a matter of	23
each of these	23
in the binding	23
and adverse effects	23
did not show	23
knowledge graph completion	23
a potential drug	23
huang et al	23
about of the	23
the respiratory system	23
of drug development	23
of cyp d	23
the evolution of	23
we used the	23
of the complex	23
proteins such as	23
other types of	23
to bind to	23
walled carbon nanotubes	23
cov and sars	23
strength of the	23
by the pharmacist	23
that they are	23
as drug delivery	23
as one of	23
the advantages of	23
the most abundant	23
to review the	23
in the prevention	23
structures of the	23
of treatment with	23
be a potential	23
which is an	23
into the host	23
the human protein	23
as a prophylactic	23
for the patient	23
is a need	23
is known as	23
the virus to	23
may be useful	23
the japanese respiratory	23
molecular weight and	23
and have been	23
among the most	23
binding affinity of	23
of colchicine in	23
only of the	23
it possible to	23
close to the	23
produced by the	23
effects of a	23
leads to a	23
in the near	23
in severe cases	23
ongoing clinical trials	23
available on the	23
angiotensin receptor blockers	23
basis for the	23
the sum of	23
high risk of	23
of them were	23
methods for the	23
the near future	23
is considered to	23
treatment of hiv	23
protein of sars	23
is effective in	23
in most of	23
effectiveness of the	23
the loss of	23
the response to	23
been studied in	23
and is a	23
is necessary for	23
phase ii trial	23
an evaluation of	23
treatment of lung	23
for the patients	23
intensive care units	23
have been published	23
consists of a	23
of potential drugs	22
exhibit is to	22
the ratio of	22
to support the	22
infection in vitro	22
two types of	22
only in the	22
oral drug delivery	22
it will be	22
the toxicity of	22
the most recent	22
of amino acids	22
of these agents	22
elimination of the	22
a model for	22
the viral replication	22
challenges and recommendations	22
a author funder	22
was defined as	22
it is made	22
of the offending	22
in vivo in	22
for oral delivery	22
that in the	22
when there is	22
as opposed to	22
most of them	22
used to determine	22
of fda approved	22
been proposed to	22
when they are	22
m proton channel	22
of the national	22
point of view	22
replication of sars	22
summarized in table	22
analysis was performed	22
an underlying disease	22
the opportunity to	22
an in silico	22
symptoms such as	22
they may be	22
carcinoma of the	22
to the other	22
we aim to	22
of laboratory animals	22
a method for	22
patients with pneumonia	22
can be easily	22
in man and	22
in the heart	22
on the efficacy	22
a role for	22
generalized exanthematous pustulosis	22
relation to the	22
indicated that the	22
in a more	22
during the course	22
been demonstrated in	22
the systemic circulation	22
conditions of the	22
has become a	22
to validate the	22
to the cell	22
interactions between the	22
primary health care	22
because they are	22
development of novel	22
the current study	22
signs and symptoms	22
novel coronavirus from	22
the state of	22
drug has been	22
the changes in	22
with coronavirus disease	22
take advantage of	22
were identified and	22
for novel coronavirus	22
a few days	22
a class of	22
the affinity of	22
rapid identification of	22
essential for the	22
in the gastric	22
for in silico	22
the human genome	22
been approved by	22
methods have been	22
a day or	22
results of an	22
in health care	22
should be conducted	22
the transmission of	22
of the heart	22
a phase i	22
reported to have	22
red blood cells	22
it has a	22
the treatment and	22
the cleavage of	22
france please specify	22
combined with other	22
antiviral activity and	22
a cause of	22
drugs with a	22
age of years	22
the ns a	22
potential to be	22
in more than	22
of the high	22
to be able	22
was no significant	22
is in the	22
in the active	22
to control the	22
to the lung	22
of drug candidates	22
to play a	22
treatment in the	22
was performed to	22
if there is	22
venom of the	22
with a history	22
of medication reconciliation	22
is to be	22
the risk for	22
the problem of	22
a retrospective cohort	22
the drugs and	22
leading to a	22
reduce the risk	22
based drug repurposing	22
of the receptor	22
is a useful	22
more than half	21
required for the	21
these findings suggest	21
breast cancer patients	21
novel coronavirus pneumonia	21
drug repurposing and	21
evolution of the	21
the time and	21
used in a	21
to the treatment	21
treatment of respiratory	21
pharmacokinetics and pharmacodynamics	21
cells treated with	21
are important for	21
to generate a	21
drugs and vaccines	21
adults and children	21
been developed to	21
made available under	21
rapid development of	21
a major role	21
of exposure to	21
be useful to	21
formation of the	21
with each other	21
used to assess	21
one of them	21
under a author	21
that they have	21
if they are	21
maximum adsorption energy	21
of the infection	21
use of drugs	21
the costs of	21
at room temperature	21
results of this	21
as long as	21
the coronavirus disease	21
treatment of coronavirus	21
available under a	21
proteins involved in	21
treatment of influenza	21
after treatment with	21
but also the	21
of the primary	21
hydrogen bonds with	21
is to provide	21
human african trypanosomiasis	21
in which a	21
of which is	21
is the main	21
have been approved	21
the sars coronavirus	21
at least two	21
pediatric patients with	21
we used a	21
polymorphisms in the	21
and type of	21
in the water	21
is a risk	21
use of antibiotics	21
drugs on the	21
of the c	21
activated charcoal in	21
been shown in	21
the results showed	21
drug use and	21
a cohort of	21
should be combined	21
to decrease the	21
a first choices	21
an animal model	21
of patients infected	21
effectiveness and safety	21
not only to	21
the characterization of	21
may be due	21
prediction of the	21
at this point	21
vast majority of	21
types of cancer	21
of this review	21
for the assessment	21
international license it	21
the community pharmacy	21
poster sessions v	21
that there was	21
and the results	21
occurs in the	21
drug for the	21
national institute of	21
in vitro activity	21
due to covid	21
of the stomach	21
be a useful	21
clinical trials of	21
included in this	21
vero e cells	21
of chloroquine hydroxychloroquine	21
patients suffering from	21
of sjs ten	21
to obtain a	21
the point of	21
is consistent with	21
interest in the	21
be seen in	21
significant differences in	21
less likely to	21
for each of	21
in health and	21
in all patients	21
molecular docking study	21
are available for	21
of nucleic acids	21
of carbon nanotubes	21
phase i clinical	21
an understanding of	21
more common in	21
has been an	21
were shown to	21
it is essential	21
at the level	21
profile of the	21
of severe covid	21
treatment with the	21
with a mean	21
mozafari et al	21
to elucidate the	21
images of the	21
induced by the	21
of the initial	21
a broad range	21
in the production	21
zhang et al	21
effective treatment of	21
clinical trial of	21
in the region	21
for a drug	21
is the major	21
and lead to	21
and other drugs	21
energy gap by	21
is made available	21
an immune response	21
and in silico	21
area under the	21
been demonstrated to	21
residues of the	21
those who are	21
it is noteworthy	21
of cases of	21
led to an	21
in human cell	21
of the gastrointestinal	21
on the drug	21
we observed that	21
virus infection in	21
determination of the	21
approach for the	21
activity against sars	21
binds to the	21
living with hiv	21
to respond to	21
the decrease in	21
believed to be	21
the mortality rate	21
of hepatocellular carcinoma	21
ranging from to	21
d structure of	21
the work of	21
to the presence	21
in vivo evaluation	21
and hepatitis c	21
give rise to	21
with a decrease	21
hospitalized with severe	21
pulmonary delivery of	21
diseases in children	21
a decrease of	21
the mean age	21
effective in the	21
in vitro model	21
the in silico	21
zhou et al	21
that should be	21
at the target	21
drug repurposing approach	21
to define the	21
the patient with	21
and health care	21
areas of the	21
of the cyp	21
license it is	21
of antimicrobial drug	20
molecules in the	20
widely used to	20
the training set	20
of new drug	20
the developing world	20
our results suggest	20
to establish the	20
in collaboration with	20
often associated with	20
in the initial	20
been applied to	20
for coronavirus disease	20
drugs for treatment	20
oxidative stress and	20
to address this	20
to the lack	20
a focus on	20
preclinical and clinical	20
patients who were	20
antiviral effects of	20
infected with sars	20
response of the	20
based on our	20
of dress dihs	20
have been made	20
management of the	20
studies have demonstrated	20
of the structure	20
the energy gap	20
to determine if	20
the anticancer drug	20