Questions

This is a list of all the questions and their associated study carrel identifiers. One can learn a lot of the "aboutness" of a text simply by reading the questions.

identifier question
cord-004101-0r2g5p1iA heat- stable hepatitis B vaccine formulation Induction of porcine dermatitis and nephropathy syndrome in piglets by infection with porcine circovirus type 3 Current status and future prospects for human papillomavirus vaccines Yeast as an expression system for producing virus- like particles: what factors do we need to consider?
cord-003656-7mzsaz7aisolated from Struthio camelus Mycoplasmas and their host: emerging and re- emerging minimal pathogens Antibiotic residues in food: the African scenario DNA- antiviral vaccines: New developments and approaches- a review Immunization of animals: from DNA to the dinner plate DNA vaccines: an historical perspective and view to the future DNA vaccines: ready for prime time?
cord-001446-mpuovmebThe utility of lung epithelium specific biomarkers in cardiac surgery: a comparison of biomarker profiles in on- and off- pump coronary bypass surgery Can serum surfactant protein D or CC- chemokine ligand 18 predict outcome of interstitial lung disease in patients with early systemic sclerosis?
cord-009877-3cyz6o9cThe common cold: Control?
cord-009784-kxa68zbc: over 100 M website views per year Ready to submit your research?
cord-010578-uib9h1lbA cluster of patients with a chronic mononucleosis- like syndrome: is Epstein- Barr virus the cause?
cord-010578-uib9h1lbThe chronic fatigue syndrome: a comprehensive approach to its definition and study Is chronic fatigue syndrome an infectious disease?
cord-257715-pbcr81qmThe seroepidemiology of genogroup 1 and genogroup 2 Norwalk- like viruses in Italy Breda virus- like particles in pigs in South Africa Inducible expression of the vaccinia virus A17L gene provides a synchronized system to monitor sorting of viral proteins during morphogenesis Porcine torovirus?
cord-275793-k0uvqcmpAn ELISA detecting antibody to conserved pestivirus epitopes Bovine virus diarrheaclinical syndromes in dairy herds Severe disease in a dairy herd associated with acute infection with bovine virus diarrhoea virus, Leptospira harjo and Coxiella burnetii Does control of bovine viral diarrhoea infection make economic sense?
cord-276989-441aclccstructural and functional characterization of the fusion core complex Illness in breastfeeding infants relates to concentration of lactoferrin and secretory Immunoglobulin A in mother's milk Coronavirus genome structure and replication Isolation and characterization of porcine epidemic diarrhea viruses associated with the 2013 disease outbreak among swine in the United States Establishment and application of indirect ELISA for detection of porcine epidemic diarrhea virus specific SIgA Intravascular and mucosal immunoglobulin A: two separate but related systems of immune defense?
cord-006828-i88on326-was hat sich verändert?
cord-006828-i88on326Aktivitätsmarker der Lupusnephritis?
cord-006828-i88on326Komplementmangels ist bisher nicht untersucht( andere Bestandteile der Kaskade?)
cord-015683-a9a82of4How are the proteomic assays helpful in aiding diagnostics?
cord-015683-a9a82of4How has the advancement in biotechnological techniques helped in diagnosis of the diseases?
cord-015683-a9a82of4What is MALDI- TOF?
cord-015683-a9a82of4What is the importance of PCR in pathogen detection?
cord-031190-4qpnlgb5The chemistry of heparin Arterial embolism occurring during systemic heparin therapy HEPARIN- A CAUSE OF ARTERIAL EMBOLI?
cord-022353-q2k2krnmA mouse bleeding technique yielding consistent volume with minimal hemolysis Transgenesis and the study of expression, cellular targeting, and function of oxytocin, vasopressin and their receptors KOs model the 100 best- selling drugs: will they model the next 100?
cord-022353-q2k2krnmInsights in asthma from overexpression transgenic modeling Genotype, obesity, and cardiovascular disease: has technical and social advance outstripped evolution?
cord-022353-q2k2krnmMildly oxidized LDL induces an increase apolipoprotein J/ paraoxonase ration The genetic control of alkaline phosphatase activity in the duodenum of the mouse Diabetes mellitus: a"thrifty"genotype rendered detrimental by"progress"?
cord-022353-q2k2krnmThe protein profile of acetazolamidetreated sera in mice bearing Lewis neoplasm CEBS object modes for systems biology data, SysBio- OM Partal hormone resistance in mice with disruption of the steroid receptor coactivator-1( SRC-1) gene Platelet factor 4 gene transfection into tumor cells inhibits angrogenesis tumor growth and metastasis Mice lacking the thyrotropin- releasing hormone gene: what do they tell us?
cord-277265-p8pns7r9Novel single gold nanowire- based electrochemical immunosensor for rapid detection of bovine viral diarrhoea antibodies in serum Development of a recombinase polymerase amplification assay for detection of epidemic human noroviruses Comparison of the oral microbiomes of canines and their owners using next- generation sequencing Identification of gastroenteric viruses by electron microscopy using higher order spectral features Aptasensors À the future of biosensing?
cord-277265-p8pns7r9The pet connection: pets as a conduit for social capital?
cord-278324-eqqvwwh6Herpes virus fusion and entry: a story with many characters Avian infectious bronchitis virus Viral respiratory diseases( ILT, aMPV infections, IB): are they ever under control?
cord-281393-96j70n2za population- based study Are SARS- CoV-2 seroprevalence estimates biased?
cord-306390-pzzev8hdA comparative- descriptive analysis of clinical characteristics in 2019-coronavirus- infected children and adults Clinical analysis of 31 cases of 2019 novel coronavirus infection in children from six provinces( autonomous region) of northern China Infection fatality rate of SARS- CoV-2 infection in a German community with a super- spreading event Comparison of four new commercial serologic assays for determination of SARS- CoV-2 IgG Immunoglobulins or convalescent plasma to tackle COVID-19: buying time to save lives-current situation and perspectives Virological assessment of hospitalized patients with COVID-19 Inactivation and safety testing of Middle East Respiratory Syndrome Coronavirus Reverse ELISA for IgG and IgM antibodies to detect Lassa virus infections in Africa Lexikon der Medizinischen Laboratoriumsdiagnostik Impact assessment of non- pharmaceutical interventions against coronavirus disease 2019 and influenza in Hong Kong: an observational study An Analysis of SARS- CoV-2 viral load by patient age Symptomatic Infants have Higher Nasopharyngeal SARS- CoV-2 Viral Loads but Less Severe Disease than Older Children Coronavirus Infections in Children Including COVID-19: An Overview of the Epidemiology, Clinical Features, Diagnosis, Treatment and Prevention Options in Children SARS- CoV-2( COVID-19): What do we know about children?
cord-014462-11ggaqf1Both ATP and GTP were utilized as phosporyl donors and Mn 2?
cord-014462-11ggaqf1Cut off was calculated as Mean negative control?
cord-014462-11ggaqf1FMDV P1- 3CD''O''vaccine gene constructs in pCDNA3.1? entrapped by the nanoparticles was prepared by using different molarity of calcium chloride and disodium hydrogen orthophosphate.
cord-014462-11ggaqf1Helicase activity of NSs was absolutely dependent on ATP and Mg 2?
cord-014462-11ggaqf1How do Indian journals perform in Maintaining quality?
cord-014462-11ggaqf1How do motivate the scientists to improve their scientific output?
cord-014462-11ggaqf1How to motivate the scientists to improve their scientific output?
cord-014462-11ggaqf1In this regard, rNSs is a unique enzyme which does not have the canonical helicase motifs but can catalyze dsDNA/ dsRNA unwinding in an ATP and Mg 2?
cord-014462-11ggaqf1Should we compare the growth of Indian science with other developed countries?
cord-014462-11ggaqf1What ails Indian Science?
cord-014462-11ggaqf1What criteria should be adopted to judge the quality and standard of scientific research?
cord-254318-w8wrn9lxIs COVID-19 receiving ADE from other coronaviruses?
cord-025922-84pheilugold Open Access which fosters wider collaboration and increased citations maximum visibility for your research Ready to submit your research?
cord-287590-jjft3denTransmissible gastroenteritis of swine: stability of coronavirus in gastric and intestinal contents Two amino acid changes at the N- terminus of transmissible gastroenteritis coronavirus spike protein result in the loss of enteric tropism Natural infection with the porcine respiratory coronavirus induces protective lactogenic immunity against transmissible gastroenteritis Periodate or glutaraldehyde for preparing peroxidase conjugates?
cord-297684-9q3oopazLateral flow assays Enzyme- linked immunosorbent assay( ELISA) Chemiluminescent immunoassay technology: what does it change in autoantibody detection?
cord-293393-kbndie8eWill the lipid load of this lipocalin change its function?
cord-291104-6chpmgryWe sought to answer an important question in cancer diagnosis: is OPN present at diagnostic levels in the blood of cervical cancer patients?
cord-327890-ocisq7e4: what decides the outcome?
cord-311811-nrodyagiOr, were they among the"worried well"?
cord-284841-flhfagp3What Cost?
cord-284841-flhfagp3What can we do without SARS- CoV-2-IgG detection? 9%)
cord-311349-145kwny3Is anti- doping analysis so far from clinical, legal or forensic targets?
cord-311349-145kwny3what next?
cord-336899-zngp67tbCOVID‐19: are neutralizing antibodies neutralizing enough?
cord-333026-9f6ecg30How contagious are common respiratory tract infections?
cord-318266-i8x80knqOf the sera cross reacting in the ELISA 14/ l 5 had a titre of Q 1: 160 in the IFAT for 3.?
cord-322529-3xn5v54sEvaluation of a latex agglutination kit( Virogen Rotatest) for detection of bovine rotavirus in fecal samples Rotavirus and other viruses of diarrhea Shedding of rotavirus in feces of sows before and after farrowing Comparison of a commercial enzyme- linked immunosorbent assay with electron microscopy, fluorescent antibody, and virus isolation for the detection of bovine and porcine rotavirus Periodate or glutaraldehyde for preparing peroxidase conjugates?
cord-334968-gonx5taqThe murine coronavirus hemagglutinin- esterase receptor- binding site: a major shift in ligand specificity through modest changes in architecture Phylogenetic and evolutionary relationships among torovirus field variants: evidence for multiple intertypic recombination events Longitudinal serological and virological study on porcine torovirus( PToV) in piglets from Spanish farms Detection and molecular characterization of porcine toroviruses in Korea Vaccinia virus: a suitable vehicle for recombinant vaccines?
cord-331277-fjsuo3yyEnhanced lateral flow immunoassay using gold nanoparticles loaded with enzymes Severe Acute Respiratory Syndrome Coronavirus 2-Specific Antibody Responses in Coronavirus Disease Good IgA Bad IgG in SARS- CoV-2 Infection?
cord-006860-a3b8hyyr( platelet count< I50/~L) or a relative decrease in platelet count(?
cord-006860-a3b8hyyrThe examination reveals, that Fg- Au was present in a low density on the platelet surface, in higher density in the surface connected system( SCS), in coated pits and vesicles and separated smooth vesicles( representing endosomes?)
cord-006860-a3b8hyyrThe superpositisn of hepatitis infections on the treatment with blood and native blood products in most of the cases has let unanswered the question related to the mechanism of the immunodeficiency: the hepatitis B or C infections or the negative impact of the itarative important alloantigenlc load?
cord-346320-ysgz6adrHyperimmune IV immunoglobulin treatment: a multicenter double- blind randomized controlled trial for patients with severe 2009 influenza A(H1N1) infection SARS: systematic review of treatment effects Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A( H1N1) 2009 virus infection Meta- analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment?
cord-344309-6c2wttxgIdentification of two novel B cell epitopes on porcine epidemic diarrhea virus spike protein Porcine epidemic diarrhea virus infection: etiology, epidemiology, pathogenesis and immunoprophylaxis Does circulating antibody play a role in the protection of piglets against porcine epidemic diarrhea virus?
cord-022653-qa1uph35Prevalence of wood dust sensitization in occupationally exposed workers in Germany- What can be tested?
cord-022653-qa1uph35Should we screen children with bronchial asthma for primary immune deficiencies?
cord-022653-qa1uph35| Is specific immunotherapy effective in subjects suffering from VKC?
cord-022653-qa1uph35| Oral immunotherapy with peach- juice in lipid transfer protein( LTP) allergy: is it possible to reach tolerance?
cord-349744-8cg5yj20-sixth update The standard coronavirus test, if available, works well- but can new diagnostics help in this pandemic?
cord-015147-h0o0yqv8Here we report on the development of the PGE2 mimetic combination therapy( DP-837953) that inhibits basal and LPS/ TLR4 induced TNF-?, IL-1ß, and MMP-1, 8, 9, 13 in human and murine synovial membranes and peripheral macrophages.
cord-015147-h0o0yqv8In a murine model of chronic synovitis( dorsal skin air pouch), DP837953 dramatically inhibited IL-1ß, TNF-?, MIP2, MCP-2 and IL-8 expression, delayed the profile of leukocyte/ neutrophil extravasation and reduced exudate volume.
cord-015147-h0o0yqv8In addition, TNF-?, IL-1ß, MMP-8 and to a lesser extent MMP-9 expression/ synthesis levels were strongly suppressed as judged by RT- PCR and ELISA measurements
cord-015147-h0o0yqv8Most of the recent studies have focused on challenge- induced expression of antimicrobial peptides and have addressed the following questions:( 1) which genes are upregulated during various types of bacterial, fungal or viral infections and what are their functions?
cord-353190-7qcoxl81Different roles for CD4þ and CD8þ T lymphocytes and macrophage subsets in the control of a generalized virus infection Correlates of protective immunity in poxvirus infection: where does antibody stand?
cord-351498-bmq6zcb0A single amino acid substitution affects substrate specificity in cysteine proteinases from Fasciola hepatica Cathepsin B proteases of flukes: the key to facilitating parasite control?
cord-351498-bmq6zcb0the milky way?
cord-279406-wwdqh9qs2020, 8, 409 Exosomes and non- coding RNA, the healers of the heart?
cord-279406-wwdqh9qsHow are we going to discover new cancer biomarkers?
cord-279406-wwdqh9qsThe pathway through LC- MS method development: In- house or ready- to- use kit- based methods?
cord-279406-wwdqh9qsThe resurgence of controversy Milk A1 ß- casein and health related outcomes in humans: A systematic review biological properties and other potential effects on human health of ß- casomorphin 7: Current knowledge and concerns A method for identifying discriminative isoform- specific peptides for clinical proteomics application An isoform of AIF1 involved in breast cancer PTEN proteoforms in biology and disease How many human proteoforms are there?
cord-279406-wwdqh9qsWhat is functional and what is junk?
cord-279406-wwdqh9qsWhere did it come from, what is it, and where is it going?
cord-031907-ilhr3iu5Extracellular Vesicle- based liquid biopsy in Acute Myeloid Leukaemia: a reliable source of residual disease biomarkers?
cord-023095-4dannjjmABSTRACT E-60 DOES CEFQUINOME PENETRATE THE BLOOD BRAIN BARRIER IN THE NORMAL HORSE?
cord-342024-kaku49xdDouble- edged spike: are SARS- CoV-2 serologic tests safe right now?
cord-342024-kaku49xdGlobal profiling of SARS- CoV-2 specific IgG/ IgM responses of convalescents using a proteome microarray The role of antibody testing for SARS- CoV-2: is there one?
cord-342024-kaku49xdRapid serologic test have a role in asymptomatic health workers COVID-19 screening COVID-19 Antibody seroprevalence in Significance of serology testing to assist timely diagnosis of SARS- CoV-2 infections: implication from a family cluster Antibody testing for COVID-19: can it be used as a screening tool in areas with low prevalence?
cord-340960-abanr641182 pediatric COVID-19 patients with different severities and allergic status Blood Myeloperoxidase- DNA, a biomarker of early response to SARS- CoV-2 infection?
cord-340960-abanr641Allergy Clinical characteristics of 140 patients infected with SARS- CoV-2 in Wuhan Is global BCG vaccination- induced trained immunity relevant to the progression of SARS- CoV-2 pandemic?
cord-340960-abanr641do we know so far?
cord-334277-g3go3u02How Well Do They Actually Perform?
cord-334277-g3go3u02Should RT- PCR be considered a gold standard in the diagnosis of Covid-19? Antibody Responses to Sars- Cov-2 in Patients with Covid-19 Value of Diagnostic Testing for Sars- Cov-2/ Covid-19 Role of Serology in the Covid-19 Pandemic
cord-334277-g3go3u02The Role of Antibody Testing for Sars- Cov-2: Is There One?
cord-334277-g3go3u02Will Antibody Tests for the Coronavirus Really Change Everything?
cord-022501-9wnmdvg5Is erysipelas- associated Tinea pedis a site of streptococcal colonisation?
cord-022501-9wnmdvg5Is it necessary to incubate the BacT/ Alert blood culture bottles more than 3 days?
cord-022501-9wnmdvg5Regarding MEPM, it was 85.9% for 500 mg gid? and
cord-022888-dnsdg04n/CRTAM on gd T cells?
cord-022888-dnsdg04nAs the results show, could there not be a direct relationship between the HLA system and the development of SA or TBC, or in contrast, was the first patient missdiagnosed of TBC being a good prognosis SA?
cord-022888-dnsdg04nCould Carabin play a role of negative regulator of B cell function?
cord-022888-dnsdg04nHow is the IGSF4-CRTAM axis regulated in T cells?
cord-022888-dnsdg04na one- year prospective birth cohort study PC09/16 TO WHAT EXTENT T- SPOT.TB COULD BE USED IN THE DIAGNOSIS OF TUBERCULOSIS IN CHILDREN EXPOSED TO TB INFECTION?
cord-019347-tj3ye1mx: This research addresses the following question: when stratifying by race, gender, age, metropolitan/ rural place of residence and comorbidity, do adults with asthma have fewer ED or unscheduled office visits for urgent asthma care if they: a) have an identified primary care provider, or b) have health insurance?
cord-019347-tj3ye1mxSignificant Rr6 pre beta-2-agonists and?
cord-019347-tj3ye1mxThe patient was treated with interferon?
cord-019347-tj3ye1mxThe question was if CD30 activity in cord blood and in 1-year- old children correlates with development or not of allergy?
cord-019347-tj3ye1mxThe question,"Do you have Delta Crud?"was added.
cord-022650-phsr10jp0757| Electronic documentation of drug allergies in a tertiary hospital in Singapore: are we relying too much on it?
cord-022650-phsr10jp1049| Is PR-10 sensitization a Portuguese phenomenon as well?
cord-022650-phsr10jp1594| Allergy to wheat- dependent exerciseinduced anaphylaxis( WDEIA) proteins, without?
cord-022650-phsr10jp: Is it possible to predict and prevent asthma?
cord-022650-phsr10jpAssessing knowledge of allergic rhinitis among final year medical and pharmacy students in Croatia- Curriculum change necessity?
cord-022650-phsr10jpColonoscopy done after cessation of therapy for one month, revealed exudative ulcerous lesions, lacerations, loss of haustration compatible with colitis( inflammatory/ allergic?).
cord-022650-phsr10jpHow frequent are they and how are they treated?
cord-022650-phsr10jpHow multifaceted the clinical presentation and etiology of allergic diseases could be?
cord-022650-phsr10jpThe pollensniffer( 1385| Does the allergy risk due to pollen exposure information is useful for the allergy sufferers?
cord-022650-phsr10jpTo the question:"As asthmatic, would you suggest to an asthmatic smoker to start vaping instead of smoking?"1.3% answered no, 98.7% yes.
cord-022650-phsr10jpTo the question:"Do you take medications for your Asthma?"57% declared to use a drug as needed, 0% used a single drug daily, 16% used more than one drug daily and 27% declared"I do n't take any asthma medication".
cord-022650-phsr10jpTo the question:"Has vaping ever worsened asthma symptoms?"90% answered no, 10% yes.
cord-022650-phsr10jpTo the question:"How much nicotine do your vaping liquids have?"15% answered 0 mg/ mL, 4% 1.5 mg/ mL, 62% 3 mg/ mL, 11% 6 mg/ mL, 6% 9 mg/ mL, 1% 12 mg/ mL and 0% 18 mg/ mL.
cord-022650-phsr10jpWhat do we( not) know?
cord-022650-phsr10jpWhat is adhesion to treatment of asthmatic patients like in Argentina according to the TAI questionnaire?
cord-022650-phsr10jp| Extensively hydrolyzed formulas for the management of cow's milk protein allergy in infants: is extensive hydrolysis sufficient to guarantee success?
cord-022650-phsr10jp| Ginger: flavory, spicy … allergenic?
cord-022940-atbjwpo5, What is the role of Ministry of Health?
cord-022940-atbjwpo5Are antibiotics against which the strain is resistant inducing the changes in bacterial proteome?
cord-022940-atbjwpo5Can YKL-40 be an inflammatory biomarker in vitamin D deficiency?
cord-022940-atbjwpo5Hemolysis and test rejection: are we following a reliable process?
cord-022940-atbjwpo5His- flag tag as a fusion partner in insect expression systemgain or loss?
cord-022940-atbjwpo5How does different lead levels affect TSH, FT3, FT4, vitamin B12 and folate?
cord-022940-atbjwpo5How preeclampsia affects oxidant status and antiinflammatory potential of breast milk?
cord-022940-atbjwpo5Is this strain characterized by other differences on a proteome level?
cord-022940-atbjwpo5It was intended to shed light on some questions such as, what is the place and importance of IVD in Turkey?
cord-022940-atbjwpo5MRM transitions used were m/ z? 250/164 for 8-iso- PGF 2a and m/ z?
cord-022940-atbjwpo5MRM transitions used were m/ z? 250/164 for 8-iso- PGF 2a and m/ z?
cord-022940-atbjwpo5Medical and biological illustrations for life sciences education: Is'a picture worth a thousand words'in visualizing medicine and science?
cord-022940-atbjwpo5P-04.01.1- 006 Host- pathogen interactions: is there a relationship between TLR 4 polymorphisms and tuberculosis in a group of Turkish patients?
cord-022940-atbjwpo5P-05.01.1- 015 Does causes 1800 MHz magnetic field application KRAS and P53 mutations in colon?:
cord-022940-atbjwpo5P-09.04.4- 108 Is there any relation between 50 g oral glucose challenge test and serum total oxidant- antioxidant status in pregnant woman?
cord-022940-atbjwpo5What are the responsibilities of educational institutions?
cord-022940-atbjwpo5What is extra to learn from protein drying measurements?
cord-015394-uj7fe5y6: Do They Change during Pregnancy?
cord-015394-uj7fe5y6A Role for Intrahepatic GLUT1?
cord-015394-uj7fe5y6Androgens Influence Human Luteal Cells Function?
cord-015394-uj7fe5y6Are Contractions at 24- 32 weeks Gestation Less Painful Than Those at Full Term?
cord-015394-uj7fe5y6Could Confined Placental Mosaicism Account for Adverse Perinatal Outcomes in IVF Pregnancies?
cord-015394-uj7fe5y6Fact or Fiction?
cord-015394-uj7fe5y6Following Periconceptional Undernutrition or Twinning in Sheep?
cord-015394-uj7fe5y6In these experiments we sought to answer the question,'Does anandamide( AEA) work in the same manner as THC?'
cord-015394-uj7fe5y6Is There Evidence for Aromatase Activity in the Stroma of Postmenopausal Ovaries?
cord-015394-uj7fe5y6Is There a Role for Fatty Acids in the Pathogenesis of Pre- Eclampsia?
cord-015394-uj7fe5y6Is There a Seasonal Pattern in the Incidence of Post- Cesarean Endometritis?
cord-015394-uj7fe5y6Necessary?
cord-015394-uj7fe5y6Pregnancy Outcome?
cord-015394-uj7fe5y6Reason To Change Intrauterine Referral Practice in the Netherlands?
cord-015394-uj7fe5y6Term Preeclampsia: Any Risk for the Neonate?
cord-015394-uj7fe5y6and What Are the Roles Played by Peroxynitrite in Preeclamptic Women?
cord-001521-l36f1gp7( H1N1) 2009 viruses Pandemic A(H1N1)2009 influenza virus detection by real- time RT- PCR: is viral quantification useful?
cord-001521-l36f1gp7( iv) What are the epidemiologic and logistical factors that determine the demand- supply balance of passive immunotherapy?
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cord-001521-l36f1gp7A quantitative risk assessment of exposure to adventitious agents in a cell culture- derived subunit influenza vaccine John's Hopkins Bloomberg School of Public Health Design of an automated laboratory for high- throughput influenza surveillance Human influenza surveillance: the demand to expand Influenza: an emerging disease Avian- to- human transmission of the PB1 gene of influenza A viruses in the 1957 and 1968 pandemics Proinflammatory cytokine responses induced by influenza A( H5N1) viruses in primary human alveolar and bronchial epithelial cells Induction of proinflammatory cytokines in human macrophages by influenza A( H5N1) viruses: a mechanism for the unusual severity of human disease?
cord-001521-l36f1gp7Consequently, the more important question is''why did children live?''
cord-001521-l36f1gp7Ever since, influenza virologists have sought to answer the question''why did young adults die?''by defining the molecular characteristics of the 1918 virus that were responsible for its virulence.
cord-001521-l36f1gp7H3N2 influenza A viruses in pigs in southeastern China: potential for genetic reassortment?
cord-001521-l36f1gp7H3N2 influenza A viruses in pigs in southeastern China: potential for genetic reassortment?
cord-001521-l36f1gp7H5N1 virus Evidence of a cross- protective immune response to influenza A in the cotton rat model Heterosubtypic immunity to influenza A virus: where do we stand?
cord-001521-l36f1gp7H9N2 influenza A viruses from poultry in Asia have human virus- like receptor specificity Characterization of H9 subtype influenza viruses from the ducks of southern China: a candidate for the next influenza pandemic in humans?
cord-001521-l36f1gp7H9N2 influenza A viruses from quail in southern China Characterization of the pathogenicity of members of the newly established H9N2 influenza virus lineages in Asia Sequence analysis of the hemagglutinin gene of H9N2 Korean avian influenza viruses and assessment of the pathogenic potential of isolate MS96 Molecular characterization of H9N2 influenza viruses: were they the donors of the''internal''genes of H5N1 viruses in Hong Kong?
cord-001521-l36f1gp7How does CS-8958 move from the cell membrane to ER ⁄ Golgi?
cord-001521-l36f1gp7How many severe cases can be offered passive immunotherapy?
cord-001521-l36f1gp7In the Control of Epidemic and Pandemic Influenza 12- 13 Characterization of an influenza A H5N2 reassortant as a candidate for live- attenuated and inactivated vaccines against highly pathogenic H5N1 viruses with pandemic potential Are there alternative avian influenza viruses for generation of stable attenuated avian- human influenza A reassortant viruses?
cord-001521-l36f1gp7In vitro and in vivo assay systems for study of influenza virus inhibitors New low- viscosity overlay medium for viral plaque assays Antibacterial and antifungal activities of Cistus incanus and C. monspeliensis leaf extracts Flavan-3-ols and proanthocyanidins from Cistus incanus Inhibition of the infectivity of influenza virus by tea polyphenols Attenuation of inducible respiratory immune responses by oseltamivir treatment in mice infected with influenza A virus Anti- inflammatory activity of macrolides: a new therapeutic potential?
cord-001521-l36f1gp7Is laninamivir indeed trapped inside ER ⁄ Golgi, and does it make a complex with NA in mice?
cord-001521-l36f1gp7New technologies for meeting the global demand for pandemic vaccines Confronting the next influenza pandemic with inexpensive generic agents: can it be done?
cord-001521-l36f1gp7Novel type II transmembrane serine proteases, MSPL and TMPRSS13, proteolytically activate membrane fusion activity of hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication Is virulence of H5N2 influenza viruses in chickens associated with loss of carbohydrate from the hemagglutinin?
cord-001521-l36f1gp7Pandemic Influenza Preparedness and Response Prophylaxis or treatment?
cord-001521-l36f1gp7Qué podemos decir ahora?
cord-001521-l36f1gp7RT- PCR technique for profiling human cytokines, based on external RNA standards, readily automatable for clinical use Role of hypercytokinemia in NF- kap- paB p50 deficient mice after H5N1 influenza A virus infection Developing new antiviral agents for influenza treatment: what does the future hold?
cord-001521-l36f1gp7The average daily passenger number is 2489 based on the 2009 Annual Statistical Report on Tourism, Tourism Bureau, Taiwan( http://admin.taiwan.net.tw/english/statistics/year.asp? relno=61).
cord-001521-l36f1gp7The protein- protein interaction map of Helicobacter pylori Development of a real- time RT- PCR for the detection of Swine- lineage Influenza A( H1N1) virus infections Long- term storage and recovery of buccal cell DNA from treated cards Pandemic A(H1N1)2009 influenza virus detection by real time RT- PCR: is viral quantification useful?
cord-001521-l36f1gp7The role of influenza virus gene constellation and viral morphology on cytokine induction, pathogenesis, and viral virulence Induction of proinflammatory cytokines in human macrophages by influenza A( H5N1) viruses: a mechanism for the unusual severity of human disease?
cord-001521-l36f1gp7These observations raise the following question: could the host response be modified so patients with severe seasonal and pandemic influenza might have a better chance of surviving?
cord-001521-l36f1gp7WHO manual on animal influenza diagnosis and surveillance Antigenic characterization of influenza B virus with a new microneutralisation assay: comparison to haemagglutination and sequence analysis Seroprotection rate, meanfold increase, seroconversion rate: which parameter adequately expresses seroresponse to influenza vaccination?
cord-001521-l36f1gp7Was bacterial pneumonia the predominant cause of death in the 1918- 1919 influenza pandemic?
cord-001521-l36f1gp7What are the ratelimiting factors in the supply of passive immunotherapy?
cord-001521-l36f1gp7What is the optimal therapy for patients with H5N1 influenza Meta- analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment?
cord-001521-l36f1gp7What percentage of convalescent individuals( donor percentage) is needed in order for the program to significantly reduce pandemic mortality?
cord-001521-l36f1gp7World Health Organization WHO outbreak communications guidelines, Geneva: World Health Organization Characterization of H9 subtype influenza viruses from the ducks of southern China: a candidate for the next influenza pandemic in humans?
cord-001521-l36f1gp7a mechanism for the unusual severity of human disease?
cord-001521-l36f1gp7did the 2009'swine- origin'influenza A virus( H1N1) emerge?
cord-001521-l36f1gp7human to pig transmission in Norway?
cord-001521-l36f1gp7viruses due to substitution of aspartic acid 151 in the catalytic site-role in virus attachment?
cord-015021-pol2qm74( 3) Should future clinical trials be based on new classifications of illness such as MODS, SIRS, APACHE III, SAP II, MRM, etc., or should trials be dedicated to specific diseases-urinary tract infections, pneumonia, trauma patients, cardiac surgery and other specific problems, rather than generalized problems of sepsis, the sepsis syndrome and other classifications?
cord-015021-pol2qm743-Is the ACCP classification of sepsis useful at the bedside to select oatients?
cord-015021-pol2qm74Abnormally high skeletal muscle pO 2 in septic patients and its normalization during recovery: Evidence against tissue hypoxia but for impaired oxygen metabolism of skeletal muscle?
cord-015021-pol2qm74Administration of exogenous IFN?
cord-015021-pol2qm74And, finally, how can the participants be sure that the trial will be stopped at the right time, to ensure that no treatment is given to any patient that might be harmful?
cord-015021-pol2qm74Are all eligible patients being studied, and their results reported?
cord-015021-pol2qm74Are all the participants truly unbiased about the relative merits of the regimens being studied?
cord-015021-pol2qm74Before using the model for risk of death in septic patients, is it mandatory to validate it( by calibration, i.e. goodness of fit, and discrin'dnation, i.e., ROC curves) first on a data base using the same definition for sepsis as in the trial and secondly on the placebo group of the trial?
cord-015021-pol2qm74Can it achives a significant improvement in the septic course, organ dysfunction, and final outcome?
cord-015021-pol2qm74Conversely, administration of anti- IFN?
cord-015021-pol2qm74Correlatively the RNI inhibitor MMLA induces in vitro a decrease in the rate of bacterial killing, fxom 78% to 57%, in macrophages triggered with IFN-?+ LPS.
cord-015021-pol2qm74How can organ dysfunction and/or failure be defined?
cord-015021-pol2qm74How should we decide which of them should be brought to clinical trial?
cord-015021-pol2qm74If there is agreement that thin is an appropriate antibiotic protocol, should it not be used in all seriously ill septic patients in the hospital?
cord-015021-pol2qm74In contrast, GF109203X significantly reduced ICAM-1 expression induced by Interferon- y( IFN-?)
cord-015021-pol2qm74In fact, the IFN-? and IL-1 induced adhesion of PBMC to cytokine treated HUVEC could be downregulated by the PKC- inhibitor, whereas TNFc~-and LPS- mediated adhesion was not influenced.
cord-015021-pol2qm74In other words, should we now begin to have clinical trials on specific diseases with causes that are known and can be attacked?
cord-015021-pol2qm74Interferon-?
cord-015021-pol2qm74Is like being compared with like-are all the end points and the standards for measuring them clearly defined so that they can not be misunderstood?
cord-015021-pol2qm74Is there any role for antioxidative therapy in sepsis?
cord-015021-pol2qm74Is truly informed consent being sought that will satisfy not only the patient's right to choose what happens to him, but also the law of the land?
cord-015021-pol2qm74MIF secretion also was induced by TNFoc( 1 ng/ ml) and IFN?
cord-015021-pol2qm74MIF secretion is induced by LPS, TNFc~ and IFN?.
cord-015021-pol2qm74Macrophages of C57BL/10ScCr mice are incapable of producing interferon-~( IFN~) which we could show to be obligatory for the production of IFN?
cord-015021-pol2qm74On closer investigation the impaired IFN?
cord-015021-pol2qm74The IFN?
cord-015021-pol2qm74The absence of sensitization to LPS in Lps d C57BL/10ScCr mice was identified as being due to their inability to produce interferon-7( IFN?).
cord-015021-pol2qm74The clinical"take"rate o? cultured epithelial autografts( CEA) has been observed to Increase with transplantation to allodermls, but the reasons for the improved clinical performance have not yet been defined.
cord-015021-pol2qm74The inability to produce adequate amounts of IL-2, most likely attributable to alterations in the transmission of signals from the cell membrane to the nucleus, results in incomplete proliferative T- cell responses to antigenic stimuli, while a lack of?
cord-015021-pol2qm74There are reports of nentrophil dysfunction in inflammatory disorders of the skin( 2), Are there dysfunctions concerning the unspecific host defense in SIRS, as well?
cord-015021-pol2qm74This has not happened, however, and the question is"Why not"?
cord-015021-pol2qm74This might be due to a preexisting( genetic?) or more likely to an epiphenomenal receptor defect.
cord-015021-pol2qm74We have investigated the proinflaznmatory oytokine secretion patter~ by PMN in patients following major~hermal or tra~ matic injury and in volunteers fellowinq endotoxemia.?
cord-015021-pol2qm74What are the definitions?
cord-015021-pol2qm74What are the issues, then, in 1994, to be dealt with at this symposium and congress?
cord-015021-pol2qm74What are the mechanisms?
cord-015021-pol2qm74What is the aplpiieability of study results in typical clinical situations?
cord-015021-pol2qm74What is the availability of speciftc antibiotics at a participating hospital?
cord-015021-pol2qm74Will the patient's physicians agree to the protocol choice?
cord-015021-pol2qm74Will they be helpful in the study and esro of patients?
cord-015021-pol2qm74Will this contribute to better clinical trials, information basis and better research?
cord-015021-pol2qm74Will we benefit Oleo from a more precise classification and definition of a non- outjty, a hodgu- podge of human disorders which have charsmeristic.s and manifestations of tissue injury, inflammation and infactian?
cord-015021-pol2qm74and?-IFN and T- helper-2( Th2) acting principally in inducing antibody formation with a secretion of IL-4, IL-5, IL-10 and TNF-[3 has still to be established within the context of major trauma.
cord-015021-pol2qm74anti- IFN-?( p<0.05).
cord-015021-pol2qm74or is it better to use a specific model for each trial?
cord-015021-pol2qm74~is s?.