bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
summary conclusions	468
blood donors	386
blood group	229
blood transfusion	215
whole blood	195
blood donation	190
red blood	179
hev infection	164
virus infection	131
red cell	130
blood components	122
blood products	120
blood cells	120
blood bank	116
blood donor	103
pregnant women	99
hev rna	97
blood cell	86
transfusion reactions	83
risk factors	74
significantly higher	68
chronic hepatitis	66
orf protein	66
platelet concentrates	66
acute hepatitis	65
amino acid	65
capsid protein	65
red cells	65
latex allergy	63
cell culture	61
rna viruses	61
hev strains	58
blood donations	58
transfusion medicine	58
virus replication	57
adverse events	56
hev igg	55
rna polymerase	54
blood supply	54
abstract withdrawn	53
ng ml	53
stem cell	52
performed using	52
public health	51
flow cytometry	51
hev seroprevalence	49
statistically significant	48
cysteine protease	48
respiratory syndrome	48
adverse reactions	47
viral replication	47
room temperature	46
donor selection	46
blood services	45
control group	45
antibody screening	45
general population	45
platelet count	45
macro domain	44
blood banks	44
transplant recipients	44
hev genotypes	44
open reading	44
viral hepatitis	43
present study	43
first time	43
blood product	43
iu ml	43
total number	42
antigen expression	42
time donors	42
high density	41
organ transplant	41
blood samples	41
viral rna	40
dependent rna	40
blood service	40
hemorrhagic fever	40
trima accel	39
national blood	38
significant difference	38
transfusion service	38
monoclonal antibody	38
density multiepitope	38
hematopoietic stem	37
congo hemorrhagic	37
united states	37
cord uid	37
hev replication	37
group system	37
doc id	37
serum samples	36
iron deficiency	36
reading frame	36
ferritin levels	36
cell line	36
clinical trials	35
zoonotic transmission	35
blood collection	35
developing countries	35
infectious diseases	35
repeat donors	35
rhd gene	34
multiepitope protein	34
blood component	34
blood safety	34
clinical practice	34
hev infections	34
clinically significant	33
virus orf	33
age group	33
risk factor	33
nucleic acid	33
protease activity	33
hev protease	31
genotype hev	31
hev orf	31
blood transfusions	31
quality control	30
blood units	30
virus particles	30
female donors	30
cfu ml	30
blood groups	29
binding site	29
health care	29
study period	29
transfusion services	29
high risk	29
immune response	29
rna virus	29
sickle cell	29
amino acids	29
viral macrodomains	29
transfusion reaction	28
may also	28
acute respiratory	28
blood centers	28
lg ml	28
red cross	28
positive samples	28
respiratory viruses	28
genomic dna	27
porcine circovirus	27
hb levels	27
like cysteine	27
syndrome virus	27
porcine reproductive	27
terumo bct	27
nipah virus	27
hev gt	27
developed countries	27
male donors	27
chain reaction	26
low hb	26
results suggest	26
generation sequencing	26
viral genome	26
per year	26
among blood	26
foodborne viruses	26
crystal structure	26
polymerase chain	26
abo blood	26
hemolytic transfusion	26
group antigens	26
sanger sequencing	25
industrialized countries	25
increased risk	25
antiglobulin test	25
fever virus	25
significant differences	25
safe blood	25
encephalomyelitis virus	25
two groups	25
mg ml	25
iron supplementation	25
immunocompromised patients	25
rubella virus	24
platelet function	24
west nile	24
infected cells	24
side effects	24
blood center	24
chronic hev	24
family hepeviridae	24
closely related	24
immune system	24
rhd genotyping	24
autologous blood	24
rbc units	24
chronic infection	24
patients undergoing	24
previous studies	23
two different	23
virus genotype	23
liver transplant	23
schizophrenia patients	23
transfusion safety	23
strand rna	23
cell disease	23
receptor binding	23
complete genome	23
cell lines	23
rhd negative	23
higher risk	23
years old	23
mean age	23
even though	23
clinical symptoms	22
sf cells	22
hb content	22
severe acute	22
bone marrow	22
immune responses	22
world health	22
influenza virus	22
dna samples	22
nile virus	22
human hepatitis	22
hev particles	22
cell transplantation	22
gene expression	22
rabbit hev	22
rbc transfusion	22
column agglutination	22
high prevalence	22
syncytial virus	21
platelet transfusion	21
liver disease	21
hev prevalence	21
respiratory syncytial	21
positive results	21
time pcr	21
hendra virus	21
hemagglutinating encephalomyelitis	21
specific antibodies	21
positive donations	21
retrospective analysis	21
hev genome	21
storage period	21
monoclonal antibodies	21
plasma samples	21
wild boar	21
least one	21
determine whether	21
blood sample	21
health organization	21
platelet content	21
western blot	20
previous study	20
hev igm	20
phylogenetic analysis	20
enteric viruses	20
network analysis	20
donor deferral	20
transfusion therapy	20
transfusion associated	20
age groups	20
genome sequences	20
donor samples	20
plasma units	20
antiviral activity	20
genetic diversity	20
blood management	20
cell units	20
cell surface	20
last years	20
latex gloves	20
orf polyprotein	20
peripheral blood	20
hev antibodies	20
one case	19
stem cells	19
voluntary blood	19
middle east	19
natural rubber	19
clinically relevant	19
culture system	19
sg hev	19
recent years	19
insect cells	19
transmitted infections	19
healthcare workers	19
oral route	19
viral infections	19
significantly lower	19
samples collected	19
papain like	19
cell transfusion	19
liver failure	19
potential risk	19
sectional study	19
university hospital	19
european countries	19
hemolytic disease	19
porcine endogenous	19
liver samples	19
blood grouping	19
previously described	19
results obtained	19
indirect antiglobulin	18
additive solution	18
retrospective study	18
life cycle	18
hiv infection	18
pig farms	18
transmitted non	18
blood volume	18
another study	18
platelet concentrate	18
serum ferritin	18
packed red	18
platelet units	18
reading frames	18
human hev	18
rubber latex	18
enterically transmitted	18
ppk cells	18
united kingdom	18
hev virions	18
reactive results	18
frozen plasma	17
cd cells	17
transfused patients	17
architect i	17
virus infections	17
ae ml	17
infected pigs	17
orf product	17
ribavirin treatment	17
type i	17
recent study	17
animal movements	17
patient blood	17
neutralizing antibodies	17
next generation	17
south africa	17
reference laboratory	17
new donors	17
active site	17
transfusion practices	17
hepatitis virus	17
donor health	17
informed consent	17
hb level	17
rhd positive	17
virus rna	17
binding sites	17
tested using	17
wild rabbits	17
automated blood	17
foodborne outbreaks	17
transplant patients	17
pathogen inactivation	17
hev capsid	16
selection criteria	16
donate blood	16
cell cultures	16
transfusion practice	16
spectra optia	16
serological testing	16
bleeding patients	16
cold storage	16
massive transfusion	16
statistical analysis	16
reference sequences	16
naked hev	16
study showed	16
rhd typing	16
direct contact	16
spectrum antiviral	16
animal models	16
respiratory tract	16
quality assurance	16
bacterial growth	16
factors associated	16
important role	16
plasma exchange	16
enveloped viruses	16
residual risk	16
i sr	16
patients receiving	16
cardiac surgery	16
blood type	16
like particles	16
sequence analysis	16
bacterial contamination	16
blood pressure	16
donor screening	15
growth factor	15
orf encodes	15
truncated orf	15
nucleotide sequence	15
frequently detected	15
recombinant plasmid	15
rna interference	15
escherichia coli	15
orf gene	15
drinking water	15
hbv dna	15
significantly increased	15
pathological changes	15
molecular biology	15
described previously	15
cysteine proteases	15
foodborne transmission	15
regular blood	15
highly conserved	15
renal failure	15
pretransfusion testing	15
viral proteins	15
human health	15
clinical significance	15
wide range	15
six months	15
risk groups	15
donor safety	15
high frequency	15
nervous system	15
iron stores	15
white blood	15
stranded rna	15
fresh frozen	15
platelet yield	15
rhd exon	15
farmed rabbits	15
apheresis platelets	15
syndrome coronavirus	15
group systems	15
hev sequences	15
bact alert	15
hev seropositivity	14
commercially available	14
patients received	14
regular donors	14
fully automated	14
igg antibodies	14
protease inhibitors	14
genomic rna	14
base call	14
also found	14
dong thap	14
central nervous	14
ribose binding	14
virus entry	14
donor recruitment	14
cobe spectra	14
buffy coat	14
replacement therapy	14
hev specific	14
plc prf	14
compatible blood	14
acute viral	14
positive donors	14
tube method	14
pyramidal cells	14
coated vesicles	14
years ago	14
transfusion center	14
viral load	14
donor population	14
year period	14
virus seroprevalence	14
cmv igg	14
platelet products	14
rhd variants	14
viral macro	14
adverse effects	14
animal reservoirs	14
food handlers	14
cd monoclonal	14
platelet transfusions	14
transplant recipient	14
solid organ	14
wild boars	14
therapeutic plasma	14
logistic regression	14
iron overload	14
bedouin arabs	14
previously reported	14
transfusion recipients	14
large number	14
hev genotype	14
case report	14
platelet counts	14
donor blood	14
genetic heterogeneity	14
coding region	14
transfusion transmitted	14
virus transmission	14
iv iron	14
adverse outcomes	14
orf proteins	14
clinical samples	14
group antigen	14
normal rhd	14
infection hepatitis	14
psap motif	14
cultured cells	14
intensive care	14
samples tested	14
iron depletion	14
specific ige	13
encephalitis virus	13
analysis showed	13
plasma membrane	13
dna sequencing	13
hev strain	13
gene deletion	13
structural protein	13
pathogen reduction	13
pegylated interferon	13
high mortality	13
month deferral	13
human strain	13
human monoclonal	13
scd patients	13
extrahepatic manifestations	13
cord blood	13
different blood	13
detection rates	13
spina bifida	13
supply chain	13
study aimed	13
blood loss	13
virus hepatitis	13
antibody identification	13
contaminated water	13
three different	13
protein expression	13
infect humans	13
false positive	13
pg ml	13
results indicate	13
resequencing microarray	13
base calls	13
molecular basis	13
donor return	13
pooled platelet	13
member states	13
pig farm	13
vox sanguinis	13
ag ab	13
prospective study	13
clinical trial	13
pcp domain	13
donor retention	13
rat serum	13
sense rna	13
clinical manifestations	13
food chain	13
infectious disease	13
dromedary camels	13
randomly selected	13
negative control	13
nucleotide sequences	13
cell concentrates	13
viral infection	13
molecular virology	13
cell antigens	13
viral particles	13
virion release	13
infection among	13
allergic reactions	13
heme iron	13
family members	13
major cause	13
cell antibody	13
innate immunity	13
escape mutants	13
hiv ag	13
specific primers	13
antibody detection	13
patient safety	13
nucleic acids	13
epidemiological studies	12
european union	12
endogenous retroviruses	12
binding affinity	12
i will	12
log iu	12
iron status	12
three times	12
class i	12
care workers	12
bamboo rats	12
patients treated	12
vasovagal reactions	12
sporadic cases	12
chikungunya virus	12
mean hb	12
bat hbv	12
risk assessment	12
innate immune	12
fetal rhd	12
hev pcp	12
data analysis	12
saharan africa	12
high incidence	12
vitro quality	12
sublingual immunotherapy	12
differential diagnosis	12
antibody positive	12
culture systems	12
results show	12
human cells	12
kidney cells	12
days post	12
hla antibodies	12
sample size	12
infected individuals	12
treated cells	12
tertiary care	12
control study	12
host range	12
abo typing	12
tissue culture	12
autochthonous hepatitis	12
antiviral drugs	12
standard deviation	12
median age	12
dg gel	12
epithelial cells	12
macro domains	12
animal species	12
host cells	12
circovirus type	12
routine use	12
within days	12
pig liver	12
highly sensitive	12
host cell	12
virus antibodies	12
direct antiglobulin	12
plasma transfusion	12
quality management	12
prt system	11
health status	11
functional domains	11
significantly reduced	11
mm tris	11
respiratory virus	11
huh cells	11
rna genome	11
vesicular stomatitis	11
breast cancer	11
rhd variant	11
new zealand	11
pilot study	11
high throughput	11
multisystemic wasting	11
rbv treatment	11
hla typing	11
two years	11
gtp pools	11
lymph nodes	11
based surveillance	11
plasma dna	11
reactive samples	11
blood processing	11
significant increase	11
single nucleotide	11
reverse transcription	11
data suggest	11
storage time	11
abo genotyping	11
related viruses	11
platelet antigens	11
adverse reaction	11
southern vietnam	11
genotype hepatitis	11
also performed	11
published data	11
many countries	11
transmission routes	11
buffy coats	11
study design	11
expression system	11
cross match	11
systematic review	11
information system	11
also used	11
wasting syndrome	11
primary prevention	11
nonstructural proteins	11
helicase domain	11
human transmission	11
infectious virus	11
samples using	11
inhibitory effect	11
seroprevalence rates	11
infected patients	11
component preparation	11
apheresis platelet	11
blood centres	11
adverse event	11
hiv positive	11
human immunodeficiency	11
electron microscopy	11
molecular typing	11
molecular characterization	11
whole genome	11
blood system	11
infectious agents	11
screening tests	11
pediatric patients	11
treatment failure	11
copies ml	11
subgenomic rna	11
emerging viruses	11
stomatitis virus	11
high level	11
hemoglobin level	11
among first	11
clinical cases	11
highly prevalent	11
mortality rate	11
transmitted via	11
specific sirnas	11
liver transplantation	10
hepatoma cells	10
will also	10
helper type	10
cd count	10
several studies	10
clinical transfusion	10
ex vivo	10
mdck i	10
rbc transfusions	10
disease virus	10
forward type	10
observational study	10
renal replacement	10
hbv infection	10
capsid proteins	10
disease control	10
million donations	10
case reports	10
scrambled sirna	10
may help	10
borne viruses	10
using different	10
human infection	10
rich region	10
preoperative anemia	10
haemolytic transfusion	10
voluntary non	10
blood screening	10
recent syphilis	10
immunodeficiency virus	10
recent report	10
orf sequences	10
gradient centrifugation	10
allele frequencies	10
tube methods	10
recent studies	10
chronic liver	10
screening test	10
gel cards	10
detected variant	10
transfusion related	10
hong kong	10
negative pregnant	10
mortality rates	10
circulatory overload	10
may cause	10
group alleles	10
per unit	10
widely used	10
primary pig	10
screening assays	10
may provide	10
sheep pcs	10
confidence interval	10
bombay phenotype	10
genetically diverse	10
russian federation	10
three months	10
transfusion protocol	10
mononuclear cells	10
also showed	10
ribavirin therapy	10
novel hepatitis	10
fresh produce	10
mammalian cells	10
also known	10
risk group	10
enzymatic activity	10
recombinant hepatitis	10
dengue virus	10
genbank accession	10
units per	10
infected animals	10
viral genomes	10
host factors	10
best hit	10
virus detection	10
alanine aminotransferase	10
four genotypes	10
stool samples	10
study shows	10
rhd weak	10
antibody screen	10
cell types	10
wild type	10
significant proportion	10
one study	10
fulminant hepatitis	10
rich plasma	10
chronic infections	10
whose infection	10
swine hepatitis	10
health problem	10
kda protein	10
animal viruses	10
cdna clone	10
hemolytic anemia	10
healthy individuals	10
healthy controls	10
human hepatoma	10
commonly used	10
clinical data	10
acetylesterase activity	10
prevalence among	10
donating blood	10
latex slit	10
viral population	10
different countries	10
mean ae	10
study aims	10
protease domain	9
current study	9
healthy donors	9
human coronavirus	9
discrepant results	9
haemorrhagic shock	9
postpartum hemorrhage	9
old female	9
test results	9
human plasma	9
acid sequence	9
recent advances	9
positive dat	9
virus release	9
mouse hepatitis	9
platelet aggregation	9
clinical studies	9
total blood	9
virus genome	9
chronic adenotonsillar	9
time rt	9
adverse transfusion	9
hemopathic patients	9
tested positive	9
frozen raspberries	9
patient identification	9
food safety	9
post transfusion	9
envelope protein	9
hev persistence	9
gel electrophoresis	9
hematological patients	9
evidence based	9
hc group	9
adenotonsillar diseases	9
routine testing	9
donor adverse	9
well plates	9
two units	9
case fatality	9
occupational exposure	9
abo antigens	9
human astrovirus	9
slaughterhouse workers	9
prototype sequence	9
morpholino oligomers	9
two samples	9
finger prick	9
authors declare	9
virion types	9
pm shift	9
hypervariable region	9
pcr products	9
mirasol treated	9
genomic organization	9
sars coronavirus	9
data obtained	9
movement data	9
confirmed positive	9
hemoglobin levels	9
endemic areas	9
software version	9
active infection	9
binding domain	9
human enteric	9
pig kidney	9
sample id	9
cchfv infection	9
without agitation	9
vertical transmission	9
agglutination technology	9
clinical signs	9
blood culture	9
also determined	9
common cause	9
cytopathic effect	9
rectal swabs	9
platelet storage	9
polyproline region	9
emerging infectious	9
also tested	9
reverse type	9
stored platelets	9
dna polymerase	9
transfusion support	9
immunomodulatory mediators	9
virus capsid	9
slightly higher	9
time qpcr	9
prrsv infection	9
zoonotic infections	9
antiviral therapy	9
study group	9
may occur	9
blood establishments	9
neutralizing human	9
cohort study	9
reactive donors	9
selection process	9
abo discrepancies	9
using alinity	9
higher seroprevalence	9
one patient	9
relatively high	9
unexpected antibody	9
rare donor	9
long term	9
surveillance programmes	9
cross blood	9
inclusion criteria	9
pregnant woman	9
delayed transfusion	9
donated blood	9
samples obtained	9
intron enhancer	9
avian hev	9
drug administration	9
nonstructural polyprotein	9
nonstructural protein	9
human platelet	9
analyzed using	9
income countries	9
mouth disease	9
diverse viruses	9
rbc blood	9
avian influenza	9
i cells	9
monoclonal anti	9
received ch	9
environmental conditions	9
different hev	9
patients suffering	9
hev detection	9
pro domain	9
negative results	9
emerging zoonotic	9
blood bags	9
cd hematopoietic	9
patients whose	9
hla class	9
chronic inflammation	9
donation site	9
group i	9
current status	9
epidemiological data	9
rare blood	9
study included	9
deferral rate	9
severe transfusion	9
abo gene	9
north america	9
deferred donors	9
positive result	9
rh blood	9
nested pcr	9
mycophenolic acid	9
reverse primer	9
regional blood	9
clinical course	9
comparative study	8
applied biosystems	8
using spss	8
forward primer	8
healthy blood	8
blot analysis	8
transfusion strategies	8
low ferritin	8
protease inhibitor	8
acute phase	8
pig movements	8
human rhinovirus	8
described elsewhere	8
susceptibility gene	8
specimen collection	8
incubation period	8
abo system	8
lung injury	8
full length	8
rhd antigen	8
united arab	8
bb mode	8
binding assay	8
will help	8
positive patients	8
infected pyramidal	8
last donation	8
first step	8
causative agent	8
large numbers	8
neurological injury	8
new blood	8
latex extract	8
negative blood	8
hb values	8
immunosuppressed patients	8
may contribute	8
rna replication	8
dans des	8
simplex virus	8
frequency antigens	8
dat positive	8
compatibility testing	8
zoonotic viruses	8
positive control	8
related adverse	8
hev quasispecies	8
patient care	8
infected rats	8
routine blood	8
hev cdna	8
patient outcomes	8
variant alleles	8
polyclonal anti	8
full text	8
negative samples	8
multiplex pcr	8
dna viruses	8
flow cytometric	8
genetic characterization	8
hev sequence	8
management system	8
infecting humans	8
days storage	8
structural proteins	8
virus helicase	8
data collection	8
blood chimerism	8
thalassemia major	8
hepg cells	8
severe disease	8
body fluids	8
economic status	8
sg niv	8
hiv incidence	8
spss software	8
sigma metrics	8
primer hevorf	8
close contact	8
variant rhd	8
standard serological	8
polyacrylamide gel	8
pollen season	8
quality indicators	8
maternal plasma	8
allogeneic donors	8
better understanding	8
prototype sequences	8
homozygous mutation	8
standard treatment	8
bamboo rat	8
pork products	8
apheresis procedures	8
bovine coronavirus	8
body weight	8
better understand	8
national level	8
call rates	8
arab emirates	8
liver cells	8
molecular weight	8
conserved among	8
shelf life	8
squ students	8
gel selection	8
oxygen uptake	8
transmitted hepatitis	8
delayed hemolytic	8
functional analysis	8
infection became	8
also demonstrated	8
allele abo	8
product utilization	8
may suggest	8
molecular testing	8
igg assay	8
respiratory pathogens	8
without clinical	8
genotyping results	8
correlation coefficient	8
two patients	8
transfusion events	8
hospital population	8
previously identified	8
palatine tonsils	8
natural history	8
additive effect	8
porcine cytomegalovirus	8
apheresis donors	8
swine industry	8
herpes simplex	8
data collected	8
three years	8
flow rate	8
among repeat	8
like protease	8
progeny virions	8
serological typing	8
pathogen identification	8
higher rates	8
sid patients	8
molecular methods	8
genetic analysis	8
hiv prevalence	8
sar strain	8
cost effective	8
neutralizing activity	8
allergic reaction	8
group ii	8
high seroprevalence	8
rhd alleles	8
measured using	8
operating room	8
proteolytic processing	8
human blood	8
polyprotein processing	8
temporary deferral	8
blood unit	8
pcr assay	8
hospital transfusion	8
wnv infection	8
cell free	8
host immune	8
data indicate	8
female donor	8
allogeneic blood	8
limited resources	8
i ii	8
vaccinia virus	8
gr dl	8
domestic pigs	8
became chronic	8
blood processed	8
molecular analysis	8
lethal mutagenesis	8
medical records	8
nonstructural gene	8
genus orthohepevirus	8
zoonotic infection	8
positive rate	8
platelet cd	8
two weeks	8
regression analysis	8
results showed	8
young male	8
cdna library	8
endoplasmic reticulum	8
hev transmission	8
lactate production	8
negative donors	8
neurological tumours	8
rat hev	8
transmissible gastroenteritis	8
recombinant hev	8
igg positivity	8
phylogenetic analyses	8
reverse transcriptase	8
oral iron	8
genetic basis	8
hev vaccine	8
pig production	8
per day	8
positive correlation	8
within min	8
haemolytic disease	8
ionized calcium	8
hormone intake	8
hev entry	8
infectious dose	8
maximal oxygen	8
systemic reactions	8
vaccine development	8
hev antibody	8
sialic acid	8
conserved domain	8
highly diverse	8
prevalence antigen	8
also observed	8
retrospective review	7
crystal forms	7
reactive neutralizing	7
cfu cm	7
antibody specificities	7
placebo group	7
genome sequencing	7
health issues	7
biological activity	7
primer extension	7
hospital blood	7
found positive	7
irregular antibodies	7
rbc exchange	7
transfusion history	7
human serum	7
considered statistically	7
bacterial infections	7
transfusion sample	7
inconclusive results	7
storage conditions	7
myeloid leukemia	7
arv use	7
binding pocket	7
human beings	7
secondary structure	7
blood establishment	7
multiple myeloma	7
divalent cations	7
lutheran glycoprotein	7
neonatal alloimmune	7
test units	7
nat screening	7
genomes project	7
cv ranged	7
cmnc spectra	7
pig population	7
zikv rna	7
ml well	7
rhd exons	7
study using	7
quality parameters	7
democratic republic	7
rabbit strains	7
infected sf	7
ferritin testing	7
transmission route	7
proximal promoter	7
determined using	7
typing discrepancy	7
low prevalence	7
infected cyno	7
pgy group	7
eye drops	7
coding sequence	7
drug development	7
linked immunosorbent	7
baculovirus expression	7
hb value	7
key role	7
discordant results	7
high number	7
broad spectrum	7
abbott laboratories	7
low hemoglobin	7
transmission via	7
times per	7
young children	7
blood banking	7
potent antiviral	7
endogenous retrovirus	7
hantaan virus	7
iron intake	7
organ failure	7
rna genomes	7
donation sites	7
may play	7
medical care	7
associated cost	7
inhibits hepatitis	7
time point	7
causes acute	7
risk management	7
motor cortex	7
like virus	7
health concern	7
per procedure	7
deferral period	7
international society	7
beta thalassemia	7
rh null	7
similar clinical	7
higher frequency	7
sucrose gradient	7
one donor	7
new approach	7
infected pregnant	7
photochemical treatment	7
chemokine scavenging	7
mm nacl	7
medical record	7
transfused units	7
samples per	7
ha test	7
human pcs	7
severe anemia	7
analysed using	7
hematology analyzer	7
auto seds	7
one sample	7
ae standard	7
abattoir workers	7
capsid shell	7
igg antibody	7
higher number	7
mainly due	7
orf recombinant	7
acute liver	7
may affect	7
sulfate proteoglycans	7
oxidative stress	7
rat hepatitis	7
entry mechanism	7
rodent hepacivirus	7
viral loads	7
core xt	7
human population	7
orf products	7
sequence identity	7
gel method	7
human consumption	7
negative phenotype	7
prenatal testing	7
allogeneic hematopoietic	7
laboratory tests	7
donor recruiter	7
abbott alinity	7
using two	7
seven days	7
amustaline gsh	7
class ii	7
ml min	7
rna positive	7
prf cells	7
infect dis	7
old woman	7
square test	7
adult patients	7
donation attempt	7
genome sequence	7
care hospital	7
mekong delta	7
destroying enzyme	7
camel meat	7
pregnant donors	7
prolonged storage	7
transfusion within	7
latex sensitization	7
machine learning	7
fatality rate	7
increased mortality	7
using flow	7
host disease	7
hev exposure	7
serological assays	7
irregular antibody	7
hev isolates	7
positive pigs	7
expiry date	7
newly identified	7
coli bl	7
higher prevalence	7
neuralgic amyotrophy	7
disease caused	7
recombinant orf	7
serious adverse	7
several years	7
written informed	7
rh antigens	7
organ transplantation	7
age pigs	7
clinically important	7
mutagenic effect	7
swine hev	7
lassa virus	7
pig movement	7
binding activity	7
highest risk	7
decreased significantly	7
male donor	7
may result	7
patients without	7
beckman coulter	7
transfusion guidelines	7
serum proteins	7
cell proliferation	7
heavy chain	7
inhibitory activity	7
experimentally infected	7
different sources	7
health services	7
subgenomic messages	7
serine protease	7
target sequences	7
phase clinical	7
platelet activation	7
routine abo	7
among different	7
crystal structures	7
free dna	7
light chain	7
serum il	7
arachidonic acid	7
virus outbreaks	7
timely manner	7
african descent	7
pcr amplification	7
accel version	7
solid phase	7
linear regression	7
platelet additive	7
incidence antigen	7
risk patients	7
ethics committee	7
transfusion policy	7
maternal rhd	7
preventive measures	7
dis doi	7
sequences obtained	7
study conducted	7
cell entry	7
combination therapy	7
per donor	7
improve patient	7
manual method	7
host factor	7
probe sequences	7
duffy blood	7
studies using	7
high viral	7
specific immunotherapy	7
significant risk	7
different genotypes	7
repeat reactive	7
prc unit	7
nipah viruses	7
igg positive	7
asia type	7
saudi arabia	7
zoonotic risk	7
third trimester	7
pcv infection	7
cell attachment	7
cyno liver	7
operating procedures	7
acid sequences	7
coated vesicle	7
consensus proposals	7
genus within	7
six sigma	7
analysis revealed	7
virus sequences	7
plasma donors	7
interim platelet	7
hiv rr	7
calculated using	7
rbc donors	7
chronic disease	7
human enterovirus	7
envelope glycoprotein	7
postweaning multisystemic	7
remunerated blood	7
virus nonstructural	7
rural areas	7
next donation	7
per test	7
rhce ce	7
plant virus	7
highly pathogenic	7
donation interval	7
investigate whether	7
tumor susceptibility	7
optical density	7
ferritin level	7
outbreaks associated	7
hev antigen	7
soluble form	7
results suggested	7
serological evidence	7
three cases	7
infected blood	7
rhdi hdfn	7
tpe procedures	7
contact dermatitis	7
low level	7
using commercial	7
genomic sequences	7
eastern mediterranean	7
group matching	7
secondary prevention	7
fecal samples	7
esterase activity	7
cov macrodomain	7
method using	7
global burden	7
avian hepatitis	7
one year	7
multiple transfusions	7
sex hormone	7
tonsil samples	7
pbpc products	7
done using	7
may induce	7
igm antibodies	7
plasma freezing	7
isolated using	6
drug resistance	6
respiratory disease	6
platelet concentration	6
monocyte monolayer	6
also present	6
two donors	6
mobile blood	6
hev infected	6
blood centre	6
one report	6
monolayer assay	6
genetic variants	6
donor rbcs	6
frequently reported	6
error threshold	6
pathogen detection	6
past years	6
green onions	6
supernatant fluid	6
epitope mapping	6
neutralizing antibody	6
also reduced	6
quasispecies heterogeneity	6
protein structure	6
including human	6
acute gastroenteritis	6
abo incompatibility	6
porcine cell	6
protein content	6
also significantly	6
acceptance criteria	6
id core	6
recipients hepatitis	6
hevea brasiliensis	6
panel cells	6
length genomic	6
different criteria	6
epidermal growth	6
binding motif	6
swine kidney	6
thalassemia patients	6
thap province	6
review board	6
transmission may	6
serum sample	6
regulatory requirements	6
abo subgroups	6
blood mononuclear	6
surface antigen	6
donors aged	6
inflammatory cytokines	6
compared using	6
physical activity	6
nat testing	6
ehev particles	6
based methods	6
polymerase promotes	6
molecular epidemiology	6
current blood	6
become chronic	6
older age	6
tube technique	6
hemoglobin derivatives	6
reminder message	6
iron deficient	6
positive impact	6
known risk	6
statistical significance	6
small number	6
niv infection	6
particular interest	6
protein expressed	6
predictive value	6
rhd el	6
clinical condition	6
genome encodes	6
pid patients	6
significant reduction	6
logu ml	6
null phenotype	6
observational studies	6
hev positive	6
hh patients	6
molecular mechanisms	6
viral extinction	6
increased cd	6
frequent blood	6
also included	6
platelet loss	6
previously published	6
ec directive	6
elisa kit	6
molecular screening	6
wb units	6
apheresis collection	6
endosomal membrane	6
maternal antibodies	6
cell transfusions	6
nov outbreaks	6
pxxp motif	6
study suggests	6
next days	6
high resolution	6
purified protein	6
prrsv strains	6
nhs blood	6
rodent pegivirus	6
conformational changes	6
future studies	6
polymerase activity	6
spss version	6
quality assessment	6
nonhuman primate	6
viruses may	6
decision making	6
cell reagents	6
efficient cell	6
using pcr	6
cells infected	6
studies conducted	6
working group	6
human respiratory	6
like proteases	6
level hev	6
bronchitis virus	6
increasing number	6
synthesized rna	6
study demonstrated	6
nucleotide substitutions	6
independently associated	6
group phenotypes	6
blood guide	6
factor viii	6
frequency antigen	6
institutional review	6
methylene blue	6
therapeutic agent	6
ferritin ng	6
potent cross	6
supply management	6
international standard	6
antiviral properties	6
donation frequency	6
specific primer	6
positive group	6
nucleotide identity	6
acid residues	6
positive blood	6
rhd zygosity	6
target effects	6
study population	6
flow diagram	6
lower ph	6
leukemia virus	6
autologous donors	6
future donation	6
gmp mfi	6
also identified	6
weak positive	6
antibody titer	6
korean population	6
like viruses	6
infectious hepatitis	6
included patients	6
travel history	6
meat products	6
borne encephalitis	6
transfusion models	6
alt levels	6
donor experience	6
negative red	6
hodgkin lymphoma	6
acute infection	6
antigen typing	6
transfused platelets	6
old disease	6
del phenotype	6
antibody concentration	6
way anova	6
locally acquired	6
rbc alloimmunization	6
eye syndrome	6
consistent results	6
reactive neutralization	6
sequence specific	6
cynomolgus macaques	6
high specificity	6
viral membrane	6
central blood	6
surface proteins	6
hev macrodomain	6
allergic patients	6
endemic regions	6
erythrocyte antibody	6
detection methods	6
serologically apparent	6
analyses showed	6
thank dr	6
virus families	6
washed three	6
red crescent	6
cells transfected	6
care unit	6
transfusion platelet	6
blind placebo	6
stranded positive	6
virus neutralization	6
des cellules	6
primarily transmitted	6
htl epitopes	6
social media	6
also reported	6
structural basis	6
two viruses	6
temporarily deferred	6
stored sheep	6
attachment glycoprotein	6
abo discrepancy	6
splice junctions	6
cd gene	6
rhd protein	6
three open	6
novel virus	6
human samples	6
hev life	6
blind passage	6
young blood	6
donor pool	6
routinely used	6
among donors	6
null individuals	6
chain shuffling	6
hdfn due	6
platelet apheresis	6
closed system	6
care system	6
evaluated using	6
rbc alloantibodies	6
following criteria	6
regulatory framework	6
spectrin matrix	6
using automated	6
surgical procedures	6
high expression	6
uk blood	6
hev helicase	6
incident hiv	6
lifestyle behaviors	6
cd expression	6
alloantibody formation	6
kir dl	6
igm igg	6
component therapy	6
repeat blood	6
rh antigen	6
human bocavirus	6
vero cells	6
viral life	6
urgent need	6
yeast two	6
serum levels	6
first blood	6
cell antibodies	6
data demonstrate	6
inhibits viral	6
available data	6
trypsin cleavage	6
hev transcription	6
infected humans	6
farm hev	6
hydrogen bond	6
high sequence	6
significantly different	6
viral clearance	6
variant allele	6
accession number	6
inventory management	6
platelet autoantibodies	6
containing receptors	6
sequencing detected	6
granulocyte transfusion	6
closely monitored	6
enveloped hev	6
medical history	6
per well	6
sequence data	6
may lead	6
rh kell	6
agricultural workers	6
higher hev	6
protein band	6
protein interaction	6
variable domain	6
typing discrepancies	6
clerical errors	6
antifungal activity	6
cell fusion	6
prevalence rate	6
orf capsid	6
enzyme activity	6
sporadic acute	6
hepatitis worldwide	6
significant decrease	6
nucleoside analogue	6
gel card	6
workers exposed	6
donors increased	6
spth cells	6
specific anti	6
per sample	6
safe transfusion	6
novel genotype	6
deferral reasons	6
gastroenteritis virus	6
active hev	6
storage duration	6
apparently healthy	6
directive ec	6
th donation	6
case study	6
fetal blood	6
blood bag	6
assure consistent	6
samples showed	6
dubai blood	6
architect anti	6
zoonotic pathogens	6
analysis using	6
agarose gel	6
medical treatment	6
leukocyte reduction	6
positive direct	6
storage lesion	6
cell donors	6
takes place	6
infection may	6
host tropism	6
tested samples	6
fresenius kabi	6
prbc unit	6
three groups	6
human pathogens	6
disease spread	6
ml kg	6
high levels	6
fold higher	6
old transfusion	6
treatment option	6
fusion protein	6
antibody library	6
premedication rate	6
cellular receptors	6
manual tube	6
reported cases	6
negative women	6
group genes	6
continuous flow	6
mechanisms underlying	6
hb increment	6
return rates	6
nucleotide synthesis	6
scid mice	6
transfected cells	6
emergency uncrossmatched	6
expression level	6
donation screening	6
donor typing	6
human viruses	6
strains circulating	6
exceptionally potent	6
hcv infection	6
molecular cloning	6
taken together	6
transcription factors	6
study found	6
transfusion transmission	6
study provides	6
acute infections	6
low haemoglobin	6
megakaryocytes differentiation	6
species orthohepevirus	6
donor lapse	6
january st	6
respiratory secretions	6
well established	6
concentrates derived	6
theraflex mb	6
ingoing closeness	6
also detected	6
spike protein	6
enteric virus	6
help us	6
mean ce	6
ppmo hp	6
transfusion laboratory	6
low ph	6
dce dce	6
epitope specific	6
potent inhibitor	6
du virus	6
frozen berries	6
aa residues	6
performed according	6
type del	6
average values	6
although hev	6
specific treatment	6
distal ribose	6
persistent postpartum	6
inhibit hev	6
cervical mucus	6
endemic countries	6
neo iris	6
culture supernatant	6
multiepitope construct	6
rattus norvegicus	6
hrv serotypes	6
male recipients	6
phase i	6
foodborne illness	6
virus presence	6
blood demand	6
significantly decreased	6
neutralising antibodies	6
cdna libraries	6
electron microscopic	6
ordering prc	6
group ab	6
density maps	6
surface area	6
rhd beadchip	6
hiv follow	6
serological techniques	6
acute hev	6
secondary testing	6
human cases	6
homology model	6
harvesting areas	6
marrow donors	6
hepatitis viruses	6
irradiated rbcs	6
complex therapy	6
repeated blood	6
buccal swab	6
caliciviridae family	6
virus among	6
hla antibody	6
ottingen minipigs	6
cell ratios	6
artificial tears	6
electronic medical	6
naturally infected	6
donation attempts	6
typing results	6
deer meat	6
adenotonsillar tissues	6
repeatedly reactive	5
different red	5
like particle	5
nine patients	5
barr virus	5
lipid envelope	5
rna using	5
without compromising	5
allele frequency	5
gel coombs	5
great potential	5
specific weight	5
cell activation	5
nucleotide polymorphism	5
experimental infection	5
seasonal variation	5
chimeric antigen	5
evaluation data	5
donation patterns	5
platelet antibodies	5
answered yes	5
facilitate hev	5
hcv screening	5
human biopl	5
immunized women	5
received blood	5
rattus tanezumi	5
animal origin	5
studies indicate	5
immucor bioarray	5
serologic testing	5
drug repurposing	5
lamina propria	5
latex exposure	5
antibody tests	5
time blood	5
highly variable	5
previous transfusion	5
chymotrypsin like	5
serologic typing	5
cell tropism	5
dizygotic twins	5
higher concentrations	5
study reports	5
full genome	5
epithelial cell	5
significant variation	5
autoimmune haemolytic	5
terminal region	5
id rhd	5
positive cases	5
standard procedures	5
hfe mutations	5
healthcare system	5
high endemicity	5
immunosorbent assay	5
serum alt	5
pgy physicians	5
mammalian cell	5
inflammatory cytokine	5
transfusion centers	5
acid testing	5
gastroenteritis outbreaks	5
acute lung	5
ml whole	5
heart failure	5
rna negative	5
one serotype	5
results indicated	5
contaminated blood	5
international users	5
sz group	5
one week	5
viruses infecting	5
prevention strategies	5
i interferon	5
complement activation	5
human rhinoviruses	5
immature hastv	5
ka ks	5
acute hbv	5
infectious bronchitis	5
recovered individuals	5
rodent species	5
next best	5
free system	5
function testing	5
monophosphate dehydrogenase	5
mental illness	5
two phases	5
liver cirrhosis	5
bb tm	5
still unknown	5
bat species	5
southeast asia	5
additional evidence	5
inactivation treatment	5
bovine serum	5
infectious hev	5
gene therapy	5
rat hepaciviruses	5
clinical outcomes	5
post donation	5
allergic diseases	5
dry eye	5
japanese encephalitis	5
serological findings	5
virus encephalitis	5
cap structure	5
inosine monophosphate	5
among patients	5
first line	5
high hev	5
ferret serum	5
existing data	5
inhibition assay	5
western europe	5
warm aiha	5
gene editing	5
hav igm	5
healthy subjects	5
middle cerebral	5
antiviral adp	5
stromal cells	5
hev virion	5
rhd status	5
swiss red	5
published studies	5
african blood	5
vast majority	5
pcv antigen	5
slightly lower	5
cross sectional	5
incidence antigens	5
increased number	5
million infections	5
transfusion indications	5
leukaemia virus	5
transcription factor	5
hybrid genes	5
several countries	5
healthcare staff	5
changes observed	5
last transfusion	5
elimination half	5
rc societies	5
ready gene	5
blood conservation	5
th hour	5
higher binding	5
bleeding prevention	5
titration end	5
igg titers	5
type iv	5
weak subgroups	5
substrate concentration	5
pediatric population	5
normal blood	5
detection limit	5
pegfp vector	5
virus assembly	5
compatible units	5
viruses detected	5
gpiib iiia	5
auckland island	5
plasma donation	5
automated system	5
management systems	5
transplant tpe	5
lymph node	5
mediated endocytosis	5
changed significantly	5
rbc chemokine	5
structural gene	5
confirmatory tests	5
transfused blood	5
storage lesions	5
serological methods	5
ribavirin inhibits	5
eligible donors	5
paediatric cardiac	5
detected hev	5
life threatening	5
fluorescence intensity	5
younger age	5
rbc antigens	5
axonal terminals	5
epidemiological study	5
technical assistance	5
dietary iron	5
false reactive	5
via contaminated	5
signal sequence	5
intercept tm	5
intercept treatment	5
risk behaviours	5
well studied	5
seasonal variations	5
seasonal pattern	5
positive antibody	5
standard operating	5
fulminant liver	5
passenger leukocytes	5
staphylococcus aureus	5
antiviral strategy	5
pc supernatant	5
samples containing	5
controlled study	5
medium containing	5
ml per	5
medication question	5
high rates	5
pig thyroid	5
vertically transmitted	5
test period	5
platelet unit	5
donation deferral	5
frozen strawberries	5
immunocompromised individuals	5
diagnostic testing	5
ige antibodies	5
donor panel	5
within months	5
entry process	5
naip regions	5
depressive symptoms	5
per cell	5
bovine tuberculosis	5
length orf	5
zinc salts	5
immune cells	5
virus species	5
occupational risk	5
wild rats	5
attending population	5
ab rna	5
different kinds	5
swine hemagglutinating	5
important cause	5
negative group	5
line treatment	5
statistical methods	5
large outbreak	5
donors received	5
ebola virus	5
transgenic pigs	5
length genome	5
least two	5
transfusion chain	5
collection using	5
blood separation	5
zoonotic potential	5
elution test	5
prospective observational	5
related acute	5
cerebral artery	5
prototype regions	5
transmembrane envelope	5
log reduction	5
protein sequences	5
close proximity	5
standard dose	5
extended storage	5
may serve	5
reveos device	5
capping enzyme	5
existing liver	5
positive strand	5
venous hemoglobin	5
fold increase	5
platelet derived	5
farmed bamboo	5
infection status	5
accession numbers	5
seroprevalence among	5
search terms	5
docking score	5
per month	5
blood count	5
studies will	5
four major	5
donate plasma	5
clinical efficacy	5
fully sheeted	5
using standard	5
rbc antibodies	5
common antibody	5
staphylococcus epidermidis	5
venous blood	5
low iron	5
virus attachment	5
lesser extent	5
basophil activation	5
postmenopausal women	5
rh phenotype	5
study revealed	5
abo antigen	5
antibody mediated	5
tropical regions	5
abattoir survey	5
using samples	5
specific monoclonal	5
hav infection	5
weak agglutination	5
neg rbcs	5
age limit	5
volume processed	5
virus load	5
weaned pigs	5
working party	5
alkaline phosphatase	5
abbott architect	5
previously tested	5
literature data	5
binding affinities	5
human enteroviruses	5
elisa kits	5
donor age	5
iron content	5
additional group	5
laboratory parameters	5
sindbis virus	5
positive anti	5
higher platelet	5
oncology patients	5
window period	5
gastroenteritis associated	5
antibody negative	5
dat negative	5
pathogen microarray	5
latex allergens	5
tests performed	5
respiratory infections	5
animal model	5
viral populations	5
times higher	5
relatively low	5
significant effect	5
among health	5
sequencing analysis	5
vary significantly	5
well known	5
virus isolation	5
reference lab	5
observed within	5
sh domains	5
significant association	5
antiviral effects	5
serum igg	5
vaccine candidate	5
also seen	5
social network	5
control units	5
novel viral	5
enveloped hepatitis	5
following stimulation	5
transfusion centre	5
matching strategies	5
hydrophobic interactions	5
risk analysis	5
animal husbandry	5
patient population	5
common causes	5
antibody specificity	5
tract infections	5
increased significantly	5
coding sequences	5
data points	5
virus strain	5
plasma donations	5
different cell	5
derived cells	5
gata binding	5
cell epitopes	5
trauma centers	5
assessed using	5
haemagglutinating encephalomyelitis	5
positive signals	5
oxygen delivery	5
transfusion process	5
cellular gtp	5
lipid membrane	5
related mortality	5
wnv risk	5
viral outbreaks	5
stranded dna	5
kinetic parameters	5
mean serum	5
food items	5
international collaboration	5
hepatic failure	5
severe anaemia	5
matched rbc	5
positive patient	5
viruses doi	5
viral detection	5
bile samples	5
tcid ml	5
donor group	5
viruses present	5
overall bsms	5
culture medium	5
side chain	5
protein may	5
retention rate	5
lutheran blood	5
st day	5
patients presented	5
occupational health	5
students reported	5
fulminant hepatic	5
mirasol prt	5
adverse donor	5
wide variety	5
derived platelets	5
national center	5
rhd allele	5
prrsv rna	5
therapy options	5
noninvasive prenatal	5
hiv reactive	5
data processing	5
two major	5
current prevalence	5
virus genomes	5
food products	5
dependent pathway	5
compassionate use	5
rhd expression	5
reduction technologies	5
applicant donors	5
platelet quality	5
hydrolase activity	5
platelet immunology	5
testing results	5
healthy adults	5
abo grouping	5
hiv residual	5
phylogenetic trees	5
muscle tissue	5
severe thrombocytopenia	5
whitney test	5
viral infectivity	5
cell populations	5
sheep prbcs	5
zoonotic disease	5
thalassaemia patients	5
apheresis cd	5
tpc prior	5
prophylactic platelet	5
recovery process	5
collection efficiency	5
thai blood	5
mediterranean region	5
hbs level	5
million symptomatic	5
widely distributed	5
cellular therapy	5
plasmapheresis donors	5
post iv	5
little evidence	5
critically ill	5
rhd xt	5
virus isolated	5
users considered	5
donors showed	5
year old	5
large volume	5
clinical outcome	5
four hev	5
molecular mass	5
rna synthesis	5
virus stocks	5
outbreaks linked	5
still limited	5
sheep prbc	5
later study	5
island pigs	5
autoimmune hemolytic	5
virus infectivity	5
events reported	5
primary human	5
assisted assignment	5
viral polymerase	5
complex structures	5
flow cytometer	5
neutralization assays	5
provocation tests	5
highly similar	5
rhd rhd	5
high quality	5
world population	5
hev viremia	5
ill children	5
south asia	5
automated systems	5
adverse effect	5
two hev	5
blood flow	5
using anti	5
positive reactions	5
studies included	5
serological investigations	5
serotype level	5
sheet domain	5
gene product	5
sequencing panel	5
practice guidelines	5
density gradient	5
related antibody	5
rna plant	5
high lactate	5
three blood	5
platelet membrane	5
envelope proteins	5
also occur	5
interferon induction	5
recent findings	5
platelet donors	5
single vendor	5