trigram

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trigram frequency
as well as468
the expression of400
reactive oxygen species353
in this study303
the role of286
the presence of258
one of the236
the effects of225
the aim of222
the development of217
in patients with211
role in the198
the effect of197
it has been193
in response to184
oxidative stress and178
in order to171
due to the169
involved in the164
been shown to163
the treatment of160
in the presence160
the production of157
to investigate the157
the activation of156
of this study155
has been shown152
an important role146
is associated with145
study was to143
the regulation of139
this study was138
important role in137
the level of134
the present study134
oxidative stress in128
the formation of127
the use of127
on the other123
the activity of123
the pathogenesis of122
aim of this121
the other hand117
activation of the116
according to the116
of oxidative stress115
compared to the113
the release of111
in addition to109
chronic obstructive pulmonary109
is involved in108
of reactive oxygen108
a variety of108
obstructive pulmonary disease107
in vitro and105
an increase in105
as a result104
have shown that101
found to be101
the immune system98
for the treatment97
is one of96
the levels of90
can be used90
in the regulation90
of the most89
vitro and in88
and in vivo88
are involved in87
based on the86
expression of the86
showed that the85
the control group84
to determine the84
changes in the83
the number of82
in the pathogenesis81
were treated with81
in the present80
we aimed to78
used as a77
shown to be77
compared to control76
the absence of75
a number of75
in terms of75
neutrophil extracellular traps75
in the absence74
to evaluate the73
associated with the73
a role in73
in the development73
results showed that71
has been reported71
and oxidative stress71
was supported by71
materials and methods71
was shown to71
the induction of71
the results of71
was found to70
the risk of70
contribute to the70
we found that69
be used for69
the plasma membrane68
a result of68
analysis of the68
effects of the66
been shown that66
play an important66
results suggest that65
was to investigate65
of patients with65
to oxidative stress65
activity of the64
aim of the64
were determined by64
mitochondrial permeability transition64
plays an important64
we investigated the63
as compared to63
increase in the63
type diabetes mellitus62
regulation of the62
is required for62
of the mitochondrial62
compared with the62
such as the62
the accumulation of62
the generation of62
the amount of62
pi k akt62
in contrast to61
have been shown60
the most common60
study is to60
this study is59
supported by the59
the mechanism of59
dh ond pi59
be used as59
the ability of58
the inhibition of58
the impact of58
was determined by58
well as the57
a decrease in57
was used to56
leads to the56
of ros in56
high levels of55
permeability transition pore54
cancer cell lines54
used in the54
there is a54
is able to54
can lead to54
to be a54
of the protein54
the surface of53
is the most53
is an important53
the importance of53
in the lungs53
responsible for the53
effect on the53
studies have shown52
the concentration of52
smooth muscle cells52
expression levels of52
the same time52
there was no52
related to the52
in the lung52
this work was52
results indicate that52
in the treatment52
increased levels of51
be involved in51
at the same51
shown that the51
cell death in51
tumor necrosis factor50
a key role50
used for the50
was used as50
the interaction of50
the addition of49
in breast cancer49
of the present49
that can be49
the binding of48
data indicate that48
influenza a virus48
and in the48
in the liver48
inhibition of the48
the cells were48
in the brain47
structure of the47
is characterized by47
were found to47
acts as a47
the first time46
has also been46
when compared to46
as a potential46
is essential for46
human serum albumin46
aimed to investigate46
are associated with46
play a role46
molecular mechanisms of46
for the first46
mouse model of46
in the human46
of cell death45
the progression of45
increased expression of45
associated with a45
breast cancer cells45
contributes to the45
in the control45
the structure of45
and activation of45
induced oxidative stress45
part of the45
diseases such as45
cell proliferation and44
of the cell44
in our study44
in combination with44
production of ros44
the function of44
the relationship between44
leading to the44
of broccoli sprouts44
the most important44
member of the44
with respect to44
of nadph oxidase43
a mouse model43
in a dose43
most of the43
due to its43
in recent years43
was associated with43
in comparison to43
in the study43
data suggest that43
it was shown42
protective effects of42
in cancer cells42
a wide range42
was observed in42
key role in42
and cell death42
cells in the42
in a mouse42
the control of41
depending on the41
wide range of41
were significantly higher41
cells treated with41
the oxidative stress41
of ros and41
be associated with41
due to their41
the fact that41
the involvement of41
may contribute to41
present study was41
by means of41
dna damage and41
of senescent cells41
observed in the41
fatty liver disease40
were used to40
levels in the40
well as in40
levels were measured40
the influence of40
role of the40
of the study40
the ability to40
significantly higher in40
levels of ros39
and respiratory syndrome39
were analyzed by39
found that the39
resulted in a39
reproductive and respiratory39
a recent study39
to study the39
porcine reproductive and39
protective effect of39
to the control39
is known to39
in the heart39
are able to39
there is no38
levels of the38
understanding of the38
are the most38
in the blood38
of our study38
can also be38
pharmakologie und toxikologie38
gene expression in38
for the development38
may lead to38
a significant increase38
significant increase in38
the cytokine storm37
serum levels of37
have also been37
to increase the37
work was supported37
known to be37
no effect on37
from patients with37
the severity of37
mitochondrial membrane potential37
in the cytoplasm37
may be a37
activated protein kinase37
is mediated by37
cells were treated37
against oxidative stress37
found in the37
the case of37
been reported to37
yun et al36
drug delivery systems36
in the cell36
which can be36
seems to be36
in diabetic patients36
aim of our36
it was found36
which is a36
differences in the36
of ag po36
the pi k36
by flow cytometry36
in the case36
leads to a36
led to a36
these results suggest36
the molecular mechanisms36
of hydrogen peroxide35
of the disease35
with type diabetes35
oxygen species and35
the end of35
nitric oxide synthase35
respiratory syndrome virus35
oxygen species in35
of h o35
was shown that35
was performed using35
a critical role35
levels were significantly35
was found that35
the in vitro35
ond pi cells35
the study was34
mode of action34
compared to non34
to be the34
decrease in the34
squamous cell carcinoma34
a total of34
in this context34
the rate of34
the immune response34
were divided into34
foxo transcription factors34
broccoli sprouts and34
central nervous system34
and reactive oxygen34
we showed that34
indicate that the34
be due to34
no significant difference33
vascular smooth muscle33
sprouts and microgreens33
we conclude that33
an essential role33
demonstrated that the33
be used to33
the ratio of33
the lack of33
has not been33
but not in33
western blot analysis33
of prdx is33
elevated levels of33
are known to33
to play a33
effect of the33
the process of33
the synthesis of33
the loss of33
which in turn33
we show that33
be related to32
for this purpose32
it is known32
has been demonstrated32
were measured by32
the context of32
as a model32
blood samples were32
appears to be32
the dna damage32
on the surface32
to identify the32
is important for32
results show that32
apoptotic cell death32
of the human32
to understand the32
were incubated with32
in the context32
which leads to32
a member of32
a consequence of32
were shown to32
have been reported32
cell cycle arrest32
a crucial role32
has been found31
influenza virus infection31
breast cancer cell31
its role in31
the innate immune31
suggest that the31
low levels of31
endoplasmic reticulum stress31
in the mitochondrial31
essential role in31
have demonstrated that31
mechanism of action31
analysis was performed31
the transcription factor31
significant difference between31
expression level of31
the action of31
is based on31
it can be31
severe acute respiratory31
the endoplasmic reticulum31
amyotrophic lateral sclerosis31
that in the31
have been used31
of gene expression31
patients with chronic31
the mechanisms of31
the mitochondrial permeability30
revealed that the30
has been suggested30
we have shown30
and progression of30
induced cell death30
significantly higher than30
generation of ros30
of the immune30
in vivo and30
the results showed30
were able to30
discussion and conclusion30
increased oxidative stress30
in type diabetes30
was performed by30
significantly increased in30
by western blot30
is known that30
expression in the30
mrna and protein30
result of the30
the design of30
isolated from the30
caused by the30
did not affect30
also known as30
different types of30
lung epithelial cells30
cancer stem cells30
a change in30
the nlrp inflammasome30
t dm patients30
risk factor for30
transforming growth factor30
a series of30
infected dh cells30
mitochondrial dysfunction and30
dna damage response29
were detected in29
were used for29
the frequency of29
to examine the29
to reduce the29
ros production in29
cells in vitro29
and development of29
is responsible for29
function of the29
induced by the29
mg kg day29
the ketogenic diet29
unfolded protein response29
as a consequence29
h n influenza29
in chronic obstructive29
of the cells29
the percentage of29
is due to29
nlrp inflammasome activation29
effects on the29
neutrophil extracellular trap29
did not show29
acute lung injury29
the mitochondrial matrix29
members of the29
critical role in28
change in the28
the maintenance of28
required for the28
nicotinamide adenine dinucleotide28
were included in28
dna damage in28
reported to be28
a ketogenic diet28
this study we28
crucial role in28
was carried out28
herpes simplex virus28
innate immune response28
there was a28
to an increase28
the gene expression28
of dna damage28
is a major28
that there is28
t reg cells28
been reported that28
ros production and28
programmed cell death28
widely used in28
acute respiratory syndrome28
were exposed to28
higher than that28
in the expression28
fatty acid oxidation28
in vitro studies28
systemic lupus erythematosus28
the inflammatory response28
the growth of27
the pathophysiology of27
at the end27
expression of il27
was isolated from27
a cytokine storm27
oxidative medicine and27
the interaction between27
of action of27
mitochondrial dysfunction in27
of type diabetes27
respiratory syncytial virus27
could be used27
ischemia reperfusion injury27
been associated with27
of cancer cells27
of pi k27
medicine and cellular27
act as a27
the overexpression of27
by oxidative stress27
due to a27
the current study27
an inhibitor of27
in line with27
the increase in27
genes involved in27
roles in the27
properties of the27
was significantly higher27
it is also27
focused on the27
been demonstrated that27
recent studies have27
activation of nf27
important for the27
show that the27
and cellular longevity27
had no effect27
of human serum27
protein kinase c27
in endothelial cells27
components of the27
study was supported26
which is the26
cd t cells26
could lead to26
the potential to26
a concentration of26
the application of26
lead to the26
in the same26
a rat model26
than that of26
and release of26
in this work26
oxidative stress is26
in multiple sclerosis26
cancer cell line26
in a cells26
is related to26
i r injury26
resulting in the26
to the nucleus26
in immune cells26
to assess the26
depends on the26
is regulated by26
in t dm26
was used for26
labile zinc levels26
to be involved26
present in the26
insulin resistance and26
the form of26
regulatory t cells26
reduction in the26
drug delivery system26
serve as a25
increased in the25
is caused by25
implicated in the25
and can be25
in a rat25
used as an25
a reduction in25
in animal models25
addition to the25
is increased in25
side effects of25
has been used25
characterized by the25
are needed to25
of neutrophil extracellular25
prdx is involved25
was assessed by25
the tca cycle25
inhibitory effect of25
were determined in25
in the form25
a and b25
significant differences in25
gene expression and25
is to investigate24
dependent on the24
is the first24
to the activation24
in dh ond24
characterization of the24
the most abundant24
and characterization of24
the phosphorylation of24
in these cells24
amino acid residues24
is a key24
because of the24
need to be24
cells of the24
stress in the24
these data indicate24
a central role24
end of the24
study showed that24
in prostate cancer24
respiratory distress syndrome24
of vitamin d24
the central nervous24
findings suggest that24
was significantly increased24
role of prdx24
analysis showed that24
cells compared to24
activity in the24
the authors declare24
mesenchymal stem cells24
results of the24
were applied to24
acute respiratory distress24
are responsible for24
health and disease24
of the virus24
by western blotting24
in the cytosol24
and regulation of24
included in the24
was measured by24
the recruitment of24
in a variety24
the in vivo24
were associated with24
it is important24
the expression levels24
the efficacy of24
the cell cycle23
in the early23
higher than in23
patients with severe23
a source of23
the actin cytoskeleton23
in hek cells23
leading to an23
were isolated from23
and function of23
g pd deficiency23
treated with ua23
is induced by23
in labile zinc23
i and ii23
the possibility of23
results in the23
could be a23
is the main23
of the major23
the human body23
through activation of23
of t dm23
with regard to23
the reactivity of23
electron transport chain23
also be used23
effects of hydrogen23
some of the23
h o and23
more susceptible to23
the conversion of23
acute kidney injury23
these results indicate23
respiratory syndrome coronavirus23
ag po under23
in the kidney23
the changes in23
to that of23
the oxidation of23
to improve the22
have been identified22
be responsible for22
is the major22
the onset of22
of influenza virus22
morbidity and mortality22
the purpose of22
murine model of22
of the enzyme22
a reduction of22
in oxidative stress22
be activated by22
considered to be22
it is possible22
is dependent on22
the course of22
wang et al22
in vivo studies22
prostate cancer cells22
of prdx in22
of lipid peroxidation22
differences between the22
rat model of22
essential for the22
the majority of22
in hepg cells22
in association with22
is important to22
investigation of the22
for treatment of22
in the range22
for min at22
located in the22
were obtained from22
such as il22
is supported by22
samples were collected22
the analysis of22
was induced by22
to interact with22
been implicated in22
damage caused by22
patients with covid22
evidence indicates that22
lead to a22
patients with type22
similar to the22
is known about22
in diseased tissues22
and insulin resistance22
of the whole22
were measured in22
higher in the22
were used as22
in the literature22
the present work22
overexpression of prdx21
to cell death21
difference between the21
in this review21
of the main21
to the release21
induction of apoptosis21
the proliferation of21
an increase of21
opening of the21
mutations in the21
in the current21
the activities of21
there were no21
the reduction of21
is a common21
to the development21
human breast cancer21
when compared with21
the toxicity of21
the result of21
cytokines and chemokines21
and inhibition of21
studies showed that21
of chronic obstructive21
a murine model21
the identification of21
are required for21
associated with increased21
been used in21
in which the21
in mammalian cells21
the survival of21
increased production of21
to elucidate the21
in a recent21
it seems that21
were carried out21
the combination of21
was to evaluate21
which could be21
the protective effects21
in the cells21
a role for21
important roles in21
of the compounds21
high fat diet21
due to an21
they showed that21
by activating the21
major role in21
that of the21
the investigation of21
in broccoli sprouts21
the contribution of21
mitochondrial reactive oxygen21
cytokine storm in21
reperfusion injury in21
the viability of21
central role in21
and in vitro21
the range of21
as a major21
the active site21
ros generation and21
significant decrease in21
our study was20
were higher in20
compared with control20
with the control20
the degree of20
leading to a20
from ecklonia cava20
presence of a20
characterized by a20
were infected with20
of amino acids20
a major role20
determined by the20
we observed that20
in a time20
the study of20
remains to be20
thought to be20
by regulating the20
cell death and20
and amino acid20
a significant decrease20
considered as a20
higher than the20
regulation of cell20
by binding to20
oxidative stress by20
been found to20
antiviral activity of20
of the gene20
cell viability was20
were evaluated by20
according to our20
been suggested that20
risk factors for20
we observed a20
both in vitro20
is well established20
and the expression20
by the russian20
and inflammation in20
in the central20
in a murine20
were observed in20
was added to20
we propose that20
than in the20
rats were divided20
in clinical trials20
binding to the20
in the plasma20
molecular biology and20
plays a key20
in living cells20
the secretion of20
cell lines were20
our results showed20
our results suggest20
led to the20
russian science foundation20
have been developed20
cytokines such as20
the extent of20
tandem mass spectrometry20
level of the20
positively correlated with20
the side effects20
infected cells treated20
transient receptor potential20
in the first20
mitochondrial function and20
significant reduction in20
of mitochondria in20
because of their20
the amino acid19
large number of19
physiological and pathological19
by using a19
in g pd19
and increased the19
leads to an19
was inhibited by19
of the s19
airway smooth muscle19
of molecular biology19
the expression level19
release of the19
evaluation of the19
expression of a19
inhibitory effects of19
a regulator of19
to analyze the19
we hypothesized that19
and mg kg19
modulation of the19
was aimed to19
were significantly lower19
been widely used19
by using the19
in health and19
to control group19
innate and adaptive19
mediated by the19
and has been19
cells exposed to19
insights into the19
we hypothesize that19
increased ros production19
molecular weight of19
the increase of19
prdx is also19
were found in19
were grown in19
might be a19
was able to19
to the pathogenesis19
extracellular trap formation19
of heart failure19
lymphocytic choriomeningitis virus19
concentration of gsh19
stress and inflammation19
cd and cd19
in this regard19
ag po crystals19
in this process19
of proinflammatory cytokines19
in the mouse19
correlated with the19
been used for19
in infected cells19
play a key19
response to the19
and h o19
expressed in the19
was analyzed by19
have been widely19
redox regulation of19
gene expression of19
at a concentration19
at h p19
increased risk of19
presence of the19
as compared with19
component of the19
can be activated19
b and c19
to the formation19
endothelial growth factor19
as described previously19
the occurrence of19
and it is19
in relation to19
of these compounds19
as a therapeutic19
pentose phosphate pathway19
cells were infected19
of the cellular19
as a new19
in aging and19
it should be19
than that in19
we studied the19
statistically significant difference19
the uptake of19
can be a19
appear to be19
also involved in19
induced apoptosis in18
via inhibition of18
to be associated18
was applied to18
transcriptional regulation of18
cell death by18
the administration of18
suggested that the18
analysis revealed that18
the family of18
of the drug18
shown in figure18
in case of18
in mice with18
expression of genes18
not show any18
at room temperature18
in skeletal muscle18
as an important18
functions as a18
the stimulation of18
oxidative damage and18
of the three18
idiopathic pulmonary fibrosis18
of the antioxidant18
the difference of18
mitochondrial function in18
our understanding of18
was no significant18
with different concentrations18
hepatitis b virus18
to be used18
the site of18
a significant reduction18
control of the18
in elderly adults18
was evaluated by18
inflammatory effects of18
as a novel18
this suggests that18
mechanisms of action18
positive correlation between18
the inner mitochondrial18
investigate the effects18
oxidative dna damage18
patients and healthy18
results demonstrate that18
it is not18
the cell membrane18
the prevention of18
at the level18
insulin resistance in18
to inhibit the18
in the following18
wei et al18
and protein levels18
may have a18
was detected by18
levels were higher18
we demonstrate that18
and western blot18
levels were determined18
are capable of18
in tumor cells18
indicated that the18
was increased in18
samples were taken18
the inhibitory effect18
was determined using18
were detected by18
proteins involved in18
could also be18
damage in the18
the protective effect18
consistent with the18
of the two18
that the expression18
in comparison with18
no significant differences18
an in vitro18
to compare the18
antioxidant properties of18
mobility group box18
is a critical18
of antioxidant enzymes18
the wild type18
t cells in18
the management of18
is a potent18
in a concentration18
in the formation18
is thought to18
in the body18
with an increased18
different cell types18
in lung cancer18
t cells and18
studies have been18
closely related to18
development and progression17
activation of nadph17
to determine whether17
their ability to17
be used in17
between the groups17
with h o17
vascular endothelial growth17
to decrease the17
we examined the17
highly expressed in17
in type diabetic17
dependent protein kinase17
decreased in the17
of the inflammatory17
alveolar epithelial cells17
to contribute to17
of fatty acid17
surface of the17
the viral infection17
concentration of the17
significantly lower in17
the development and17
hematopoietic stem cells17
the rats were17
leading cause of17
compared to controls17
with g pd17
in copd patients17
in the rat17
the most widely17
to test the17
little is known17
significant difference in17
we analyzed the17
may be involved17
was performed to17
epidermal growth factor17
suggests that the17
may play a17
peer review of17
conflict of interest17
a review of17
lung cancer cells17
airway epithelial cells17
caused by a17
results of this17
reduction of the17
of the innate17
it is well17
plasma membrane and17
which is associated17
is activated by17
reported that the17
the basis of17
of the receptor17
induced dna damage17
of prdx and17
on the expression17
decreased expression of17
will be discussed17
antioxidant activity of17
is a member17
under oxidative stress17
polymerase chain reaction17
been found in17
was performed on17
cause of death17
cytotoxic effects of17
induction of the17
alterations in the17
was accompanied by17
been identified as17
and nitric oxide17
x for peer17
advanced glycation end17
a link between17
these data suggest17
suggesting that the17
is critical for17
authors declare no17
in the future17
biology and genetics17
for peer review17
hsa and bsa17
correlation between the17
conditions such as17
inner mitochondrial membrane17
group as the17
a model of17
has been associated17
of the lung17
and healthy controls17
in cystic fibrosis17
used to treat17
it could be17
fold higher than17
hepatitis c virus17
similar to that17
superoxide dismutase catalase17
a family of17
and hydrogen peroxide17
and type diabetes17
on the cell17
are essential for17
nir light light17
were investigated by17
a large number17
role of ros17
oxidative stress response17
state of the17
cell lung cancer17
is also a17
have been described17
we suggest that17
the influenza virus17
the determination of17
study of the17
also been shown17
as mentioned above17
and endothelial cells17
injury in rats17
were stained with17
which results in17
better understanding of17
after treatment with17
and expression of17
this indicates that17
genes related to17
for patients with16
alkaline phosphatase enzyme16
nonalcoholic fatty liver16
mechanism of the16
a wide variety16
blood glucose levels16
negative regulator of16
the modulation of16
of transcription factors16
experiments showed that16
antibacterial activity of16
wide variety of16
and polymers based16
c bl mice16
of selenium is16
was investigated by16
of the same16
piperidine morpholine ph16
used to determine16
a pivotal role16
the albumin molecule16
inactivation of the16
in the last16
from oxidative stress16
a better understanding16
blood mononuclear cells16
the treatment with16
acts as an16
difference of ph16
n influenza virus16
on coumarin derivatives16
inhibitory effect on16
immune response to16
are characterized by16
purpose of this16
in more detail16
this is the16
nitrobenzyl group as16
the antiviral activity16
the stability of16
with chronic obstructive16
its ability to16
it is a16
stress caused by16
the unfolded protein16
in the pathophysiology16
polymers with o16
to be an16
properties of albumin16
orders of magnitude16
findings indicate that16
is expressed in16
and dna damage16
inducible nitric oxide16
linked to the16
of nitric oxide16
may be the16
in human lung16
the bond energy16
sudlow site i16
the russian science16
polymers based on16
the delivery of16
be considered as16
interfere with the16
to characterize the16
as the capping16
by h o16
ros production is16
be an important16
of ph values16
supplementary figure s16
small cell lung16
interaction with the16
in the gene16
cytochrome c release16
as a source16
the conformation of16
was measured using16
and activity of16
are polymers with16
that leads to16
cells were incubated16
interact with the16
the incidence of16
h and h16
the cleavage of16
type diabetic patients16
ros in the16
to an increased16
further studies are16
has the potential16
the need for16
associated with an16
have been found16
action of the16
patients compared to16
zn acoh redox16
that has been16
therapeutic target for16
to be elucidated16
were increased in16
inhibitor of the16
the spinal cord16
ua and sf16
which may be16
as described above16
the potential of16
in regulation of16
were analyzed using16
of the plasma16
and colleagues in16
virus infection in16
these findings suggest16
protein expression of16
in the nucleus16
was confirmed by16
of copd patients16
the metabolic syndrome16
were used in16
is accompanied by16
bond energy of16
alcoholic fatty liver16
uv light nir16
apoptosis induced by16
no statistically significant16
cell cycle progression16
in colorectal cancer16
was higher than16
the efficiency of16
before and after16
liver and kidney16
based on coumarin16
in vivo experiments16
is an essential16
of the nf16
in all groups16
zhang et al16
in some cases16
the most frequent16
it was determined16
supplementary table s16
the liver and16
in this case16
the capping group16
was detected in16
their role in16
could contribute to16
light nir light16
mg micromotors and16
enzyme bsa enzyme15
be induced by15
have found that15
studies are needed15
proteins in the15
is a natural15
material and methods15
were collected from15
the opening of15
of ros production15
glycation end products15
the intensity of15
antioxidant response element15
performance liquid chromatography15
in the induction15
of the metabolic15
our results show15
expression of prdx15
both cell lines15
may be used15
were determined as15
to clarify the15
experimental autoimmune encephalomyelitis15
did not change15
plays a crucial15
not limited to15
presence of ag15
the lungs of15
based on these15
aim was to15
investigated the effects15
statistically significant differences15
department of molecular15
as shown in15
a systematic review15
of the p15
of cell cycle15
serves as a15
as an antioxidant15
needs to be15
were collected for15
of the effects15
shown to increase15
sy y cells15
the preparation of15
the transcription of15
stress and apoptosis15
mechanisms of the15
cell lines and15
is upregulated in15
lead to an15
as determined by15
there is an15
mechanisms underlying the15
acoh redox pd15
in the immune15
were subjected to15
o redox plasmin15
redox plasmin enzyme15
cells isolated from15
results indicated that15
response to oxidative15
has been identified15
of mitochondrial function15
investigated the effect15
thiols redox h15
were significantly increased15
in human breast15
at least in15
factor in the15
total antioxidant status15
contrast to the15
part of a15
our data suggest15
the cell surface15
were investigated in15
mice infected with15
the host immune15
cell viability and15
peripheral blood mononuclear15
into the nucleus15
in the s15
th and th15
of multiple sclerosis15
belongs to the15
of breast cancer15
ros and no15
fold increase in15
role in maintaining15
in the activation15
pivotal role in15
the upregulation of15
h o redox15
kg body weight15
was not affected15
wistar albino rats15
formation of the15
enzymes such as15
a hallmark of15
pathogenesis of copd15
it has also15
showed that prdx15
hydrogen peroxide and15
to find out15
all of the15
accumulation of senescent15
the participation of15
the differentiation of15
we were able15
real time pcr15
in normal tissues15
enzyme alkaline phosphatase15
of nlrp inflammasome15
morpholine ph zn15
the cytotoxicity of15
a cells were15
is not a15
relies on the15
cells and the15
in the world15
a lack of15
the extracellular matrix15
production of il15
bovine serum albumin15
redox h o15
it was also15
faculty of medicine15
than those of15
a therapeutic target15
the small intestine15
in the process15
balb c mice15
in the mitochondria15
play important roles15
to have a15
the value of15
in another study15
epithelial cells and15
not affect the15
higher levels of15
for cancer therapy15
there are many15
we used a15
significant increase of15
ph zn acoh15
obtained from the15
were performed in15
the detection of15
galactosidase enzyme alkaline15
production of reactive15
due to increased15
to the results15
studies on the15
we demonstrated that15
is considered as15
together with the15
fatty acid synthesis15
and chronic obstructive15
composition of the15
the s rrna15
the antioxidant properties15
its interaction with15
resulted in the15
and mitochondrial dysfunction15
of the body15
of manganosalen complexes15
involved in this15
our results indicate15
animal models of15
we are currently15
kim et al15
may be an15
the content of15
the capacity of15
has shown that15
dna repair and15
the changes of15
vivo and in14
in the design14
prdx can be14
signaling pathway in14
as indicated by14
along with the14
an increased risk14
studies suggest that14
regulation of mitochondrial14
divided into groups14
to regulate the14
of the er14
were performed with14
been used as14
ic values of14
followed by the14
a set of14
can be found14
mitochondrial ros production14
be found in14
of vascular smooth14
which is characterized14
immune response and14
increase the risk14
drug release in14
the nadph oxidase14
patients with diabetes14
and superoxide dismutase14
patients with g14
and protein expression14
high concentrations of14
work was to14
in vitro model14
of anticancer drugs14
canine distemper virus14
be noted that14
to prevent the14
of foxo transcription14
and identification of14
shown to play14
participate in the14
was designed to14
in cell cycle14
the patients with14
study demonstrated that14
is a novel14
there are several14
the restoration of14
mrna levels of14
analyses were performed14
data show that14
that lead to14
a group of14
for cancer treatment14
that inhibition of14
for drug delivery14
region of the14
first time that14
investigate the role14
extracellular traps in14
as a tumor14
depend on the14
significantly lower than14
the existence of14
effect of hydrogen14
binding site of14
that prdx is14
group and the14
infection in mice14
a protective effect14
in host cells14
was a significant14
by increasing the14
disulfide bonds and14
and cell cycle14
total oxidant status14
of the sample14
lung injury in14
adaptive immune responses14
of the active14
evidence suggests that14
are exposed to14
has been observed14
should be noted14
changes of the14
was performed with14
advantage of the14
the balance between14
for up to14
by inhibiting the14
there are no14
of the transcription14
was determined in14
is consistent with14
was decreased in14
was found in14
study was designed14
the time of14
on cell viability14
t cell activation14
are expressed in14
included in this14
disease characterized by14
type i interferon14
light light light14
are considered as14
and ros production14
different doses of14
of nets in14
air pollution and14
in agreement with14
site of the14
oxidative damage to14
as shown by14
h k ac14
aimed to evaluate14
with permission from14
can be induced14
were higher than14
with the aim14
development of the14
of t cells14
such as high14
aimed to determine14
in erster linie14
investigate the effect14
the discovery of14
of insulin resistance14
was evaluated using14
growth factor receptor14
that it is14
of immune cells14
the relevance of14
cells that survive14
compared to wt14
has been proposed14
are required to14
eluted from rca14
cells infected with14
and treatment of14
of the dna14
been linked to14
factors such as14
of the patients14
in the respiratory14
known about the14
the initiation of14
the length of14
cytotoxic effect of14
significant differences between14
of the actin14
the protein was14
as a marker14
stem cells and14
oxygen species production14
a loss of14
led to an14
brown alga ecklonia14
large amounts of14
the control and14
for this reason14
be able to14
immune system and14
mechanism by which14
adverse health effects14
data not shown14
function in the14
of the role14
is not clear14
the host cells14
and prevention of14
in sudlow site14
the structure and14
on oxidative stress14
mrna expression of14
in human cells14
these results are14
of colorectal cancer14
results were obtained14
into the cytosol14
was to determine14
was determined that13
determination of the13
a risk factor13
the results were13
in ca i13
with oxidative stress13
in a wide13
this could be13
the nature of13
is overexpressed in13
plays a role13
previous studies have13
proliferation and differentiation13
ec barrier disruption13
the pentose phosphate13
mainly due to13
significant role in13
similar results were13
systematic review and13
been identified in13
quantitative analysis of13
expression of pro13
a range of13
financially supported by13
analyzed by western13
amino acid sequence13
under dark conditions13
cancer cells and13
protein expression in13
expression of nampt13
of neurodegenerative diseases13
pancreatic beta cells13
with t dm13
in spite of13
have indicated that13
shown to have13
and cardiovascular diseases13
in serum and13
interacts with the13
gene expression was13
to a decrease13
has recently been13
and on the13
role in this13
in accordance with13
chronic inflammation and13
well as a13
the results suggest13
with each other13
the electron transport13
attributed to the13
disruption of the13
first line of13
permission from the13
group compared to13
protective role of13
inflammatory cytokines and13
the study is13
role of mitochondria13
various types of13
which has been13
administration of the13
g for min13
of this work13
of the brain13
and tissue damage13
in the prevention13
this work is13
through inhibition of13
the depletion of13
in neurodegenerative diseases13
signal transduction pathways13
of barbadin on13
to explore the13
demonstrate that the13
the age of13
of the nuclear13
potential of the13
an moi of13
neuronal cell death13
we have identified13
to this end13
be a potential13
according to their13
are presented as13
the gastrointestinal tract13
responsive systems can13
effects of h13
reproduced with permission13
the work was13
is used as13
reduced expression of13
beneficial effects of13
study revealed that13
those in the13
types of cancer13
of target genes13
of ursolic acid13
arts and sciences13
of the tested13
of fatty acids13
we performed a13
the circadian clock13
treated with different13
were measured with13
detected in the13
of intracellular ros13
can increase the13
injected intravitreally with13
research council of13
the response to13
those of the13
involvement of the13
foxo proteins are13
lipid peroxidation in13
are related to13
levels of il13
presence or absence13
in the level13
at low concentrations13
coronary artery disease13
has led to13
to be responsible13
of the ptpc13
ovarian cancer cells13
stability of the13
activity of ag13
lipid peroxidation and13
one of these13
and the production13
mg kg b13
comparison of the13
der spezifi schen13
the concept of13
retinas were collected13
were injected with13
only in the13
infected with rsv13
a significant difference13
of the ros13
to the accumulation13
in the spinal13
impact on the13
via activation of13
were determined using13
mediated ros production13
vitamin d deficiency13
necrotic cell death13
of the genes13
a decrease of13
transcription factors and13
under the control13
of these two13
stimulation of the13
a negative regulator13
are important for13
dose dependent manner13
relative to the13
at an moi13
to activate the13
and contributes to13
in the serum13
followed by a13
to inhibition of13
could not be13
phosphorylation of the13
is the second13
for in vitro13
and resistance to13
inflammation in the13
a marker of13
effect of barbadin13
as the most13
guanine nucleotide exchange13
in this section13
innate immune system13
in the patients13
to h o13
be attributed to13
with or without13
is possible that13
into the cytoplasm13
inflammatory responses in13
were randomly divided13
study was performed13
and the control13
be useful for13
higher than those13
academy of sciences13
reticulum stress and13
in hepatocellular carcinoma13
body mass index13
be explained by13
on the development13
dimensional structure of13
identification of the13
by measuring the13
be linked to13
identified as a13
sudlow site ii13
in the small13
is part of13
of the viral13
pathway in the13
of a single13
of arts and13
and is a13
on the immune13
production of pro13
cancer cells is13
albino rats were13
and presence of13
were compared with13
ability of the12
are shown in12
major source of12
mitochondria in the12
processes such as12
to ros production12
were performed using12
different concentrations of12
the method of12
accumulation in the12
the presence or12
are increased in12
during influenza infection12
as evidenced by12
in the levels12
treated with sf12
associated molecular patterns12
were performed on12
the availability of12
which might be12
of dh ond12
as in the12
in cell death12
in drug delivery12
adenine dinucleotide phosphate12
pharmacological inhibition of12
enzymes involved in12
protection against oxidative12
to a significant12
is known as12
were no significant12
regulator of the12
with ic values12
and tissue injury12
all of these12
indicating that the12
divided into three12
a mixture of12
with s methionine12
play a crucial12
intestinal epithelial cells12
and incubated for12
cells and their12
in the peripheral12
a role of12
are thought to12
induced lung injury12
cells such as12
thereby leading to12
treatment of the12
no conflict of12
is the only12
human gingival fibroblasts12
conditions can be12
results demonstrated that12
to the same12
is reported that12
we evaluated the12
are more susceptible12
and its role12
divided into four12
also been used12
expression in human12
we have investigated12
application of the12
not significantly different12
even in the12
was determined as12
the decrease of12
been reported in12
can be considered12
by inhibition of12
injury in the12
of the tumor12
oxidative stress caused12
that may be12
of them were12
of foxo proteins12
than in normal12
be a promising12
to be significantly12
as an alternative12
protein kinase a12
may act as12
in tumor tissues12
low molecular weight12
was achieved by12
porcine circovirus type12
is a complex12
new insights into12
the early stage12
it is reported12
control group and12
increasing concentrations of12
structure and function12
likely due to12
may be due12
for the detection12
an animal model12
and gene expression12
the recognition of12
and antioxidant capacity12
the proliferation and12
the inner membrane12
patients and controls12
role in regulating12
is correlated with12
nuclear factor kappa12
from oxidative damage12
in support of12
in heart failure12
and they are12
infected with t12
a protective role12
of free radical12
in saccharomyces cerevisiae12
number of cells12
of epithelial cells12
for the delivery12
the measurement of12
in a study12
through modulation of12
to a reduction12
nad nadh ratio12
at least partially12
of the nlrp12
and glutathione peroxidase12
necrosis factor alpha12
is that the12
or absence of12
unspezifi schen abwehr12
we used the12
senescent cells in12
was calculated as12
the jak stat12
on the basis12
the transfer of12
production of cytokines12
released from the12
nad levels in12
randomly divided into12
of cytochrome c12
cells and in12
to the virus12
statistical analysis was12
the degradation of12
to be more12
to the high12
and apoptosis in12
that could be12
breast cancer and12
innate immune responses12
the correlation between12
cell growth and12
in lung epithelial12
to induce the12
the decrease in12
cycle arrest and12
immune system to12
and accumulation of12
of p mapk12
respiratory viral infections12
inflammatory bowel disease12
the expressions of12
was significantly lower12
the nucleus and12
line of defense12
are mediated by12
to be in12
play an essential12
may serve as12
potential as a12
to investigate whether12
of the g12
a a receptor12
ischemia modified albumin12
shown in fig12
foxo and foxo12
of the total12
based on their12
by alveolar macrophages12
nitric oxide and12
oxidative stress induced12
of a variety12
used in this12
and loss of12
white adipose tissue12
an association between12
the group of12
the suppression of12
ic value of12
compared with other12
ros levels and12
the metabolism of12
the h r12
in the number12
is independent of12
were assessed by12
the ag po12
of the c12
formation of neutrophil12
induce oxidative stress12
cells were exposed12
infected a cells12
the ttc approach12
expression of cd12
was also shown12
and the release12
as the main12
a moderately high12
periodontal tissue destruction12
formation of a12
carried out by12
innate lymphoid cells12
of mitochondrial ros12
for the prevention12
also able to12
to a lesser12
was observed between12
but did not12
the mrna expression12
suggesting that prdx12
are the main12
source of ros12
modification of the12
and that the12
showed a significant12
regulated by the12
acute myocardial infarction12
concentration of mg12
we determined the12
induced activation of12
of cells with12
er stress and12
interaction of the12
were selected for12
resulting in a12
as one of12
their effects on12
of the cytokine12
as it is12
when the cells12
the etiology of12
increased generation of12
of atp and12
the most potent12
signaling in the12
contributing to the12
most widely used12
suppression of the12
in hela cells12
to act as12
consistent with this12
p and p12
and the resulting12
to reveal the12
were obtained in12
cells were cultured12
our aim was12
is also involved12
conditions of the12
two types of12
of innate immunity12
pcr and western12
been suggested to12
the respiratory tract12
in inflammatory diseases12
may be related11
activities of the11
the growth and11
data showed that11
is a promising11
concentrations of the11
and leads to11
seem to be11
amyloid precursor protein11
studies have demonstrated11
binding of the11
result in a11
responsive drug delivery11
be important in11
study we aimed11
in leydig cells11
council of turkey11
distribution of the11
isolated from ec11
were cultured in11
of inflammation and11
of these cells11
simplex virus type11
rats were sacrificed11
faculty of science11
of the infection11
might contribute to11
the transport of11
the mitochondrial membrane11
each of the11
and healthy individuals11
values of the11
infected immune cells11
it may be11
localized in the11
found to have11
induced ros production11
and the role11
t h cells11
results in an11
the tested compounds11
in primary human11
alveolar macrophages in11
increase in labile11
the scientific and11
the roles of11
be enhanced by11
decreased the expression11
in the past11
for subcellular fractionation11
development of a11
mean platelet volume11
half of the11
be concluded that11
use of the11
in rats with11
the publisher of11
plays a critical11
supported by grant11
of which is11
colon cancer cells11
degradation of the11
of the current11
heat shock protein11
vital role in11
amino acids and11
in both cell11
brown adipose tissue11
the most commonly11
with the other11
after incubation with11
ros and rns11
have not been11
of cell proliferation11
phosphate dehydrogenase deficiency11
thermo fisher scientific11
it was demonstrated11
crystal structure of11
cells were washed11
is well known11
with severe covid11
the cytoplasm and11
were performed to11
scientific and technological11
regions of the11
of apoptotic cells11
reported as a11
in human and11
are used in11
and the subsequent11
present study we11
effect was observed11
and lg ml11
the oxidative damage11
airway inflammation and11
world health organization11
in this respect11
of mitochondrial permeability11
a model for11
and protein level11
for drug release11
negative correlation between11
the cellular level11
characterization of a11
can result in11
of cd t11
cancer is the11
compared to healthy11
around the world11
potential role of11
and may be11
of prostate cancer11
of influenza a11
in human neutrophils11
type diabetes and11
were loaded with11
in favor of11
information on the11
study aimed to11
tumor suppressor genes11
is widely used11
be combined with11
and role in11
technological research council11
the modification of11
many studies have11
for h and11
senescent cells can11
acute lymphoblastic leukemia11
binds to the11
capacity of the11
can be combined11
in the intracellular11
hba c levels11
was funded by11
at g for11
of stem cells11
is a crucial11
in the tumor11
the beginning of11
to changes in11
and have a11
protein levels in11
and as a11
important role of11
as previously described11
regulate the expression11
effects such as11
a component of11
publisher of corresponding11
taken into account11
tumor promoting effect11
proteins such as11
significantly reduced the11
the underlying mechanisms11
as an anti11
this process is11
k akt pathway11
be caused by11
main source of11
in the active11
the main source11
in the clinical11
pulmonary disease and11
shown to induce11
we found a11
shown to decrease11
in the er11
it was aimed11
inflammation and oxidative11
production in the11
expression of hif11
was followed by11
of complex i11
to control and11
of nampt in11
commonly used in11
from the publisher11
there are a11
from the brown11
localization of hif11
the hypothesis that11
not affected by11
early stages of11
can be easily11
may also be11
to the cell11
activated protein kinases11
in rheumatoid arthritis11
was shown for11
these effects are11
of the extracellular11
common cause of11
which acts as11
with and without11
of h n11
increases the expression11
chronic lung disease11
did not alter11
carried out to11
another type of11
as a regulator11
of chronic inflammation11
was obtained from11
a combination of11
inhibitory activity of11
may be more11
cell viability assay11
und klinische pharmakologie11
role of oxidative11
there is evidence11
protective effect against11
jnk and p11
total rna was11
survival of t11
natural and synthetic11
high level of11
system can be11
of silver nanoparticles11
the creative commons11
faculty of arts11
the production and11
the prevention and11
release of dox11
of ecklonia cava11
s and s11
of the heart11
and its metabolites11
the observation that11
the g protein11
cells were seeded11
creative commons attribution11
at high concentrations11
our study is11
cancer is a11
viral replication and11
in this way11
inflammatory effect of11
is not yet11
prdx and prdx11
also demonstrated that11
we have recently11