This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.
trigram | frequency |
---|---|
the presence of | 184 |
as well as | 179 |
in order to | 173 |
one of the | 134 |
of the protein | 132 |
based on the | 120 |
structure of the | 101 |
the number of | 98 |
the active site | 95 |
in this study | 91 |
in the presence | 87 |
due to the | 80 |
the role of | 80 |
the effect of | 78 |
fake av software | 76 |
was used to | 75 |
analysis of the | 73 |
the formation of | 68 |
the use of | 67 |
the development of | 66 |
crystal structure of | 65 |
sites in the | 65 |
in terms of | 63 |
a number of | 61 |
we found that | 58 |
the effects of | 56 |
in addition to | 55 |
involved in the | 55 |
of the most | 54 |
of the enzyme | 54 |
can be used | 52 |
part of the | 52 |
the cleavage site | 52 |
to identify the | 50 |
a variety of | 50 |
is one of | 50 |
the majority of | 50 |
been shown to | 49 |
it has been | 49 |
understanding of the | 48 |
acute respiratory syndrome | 47 |
severe acute respiratory | 47 |
respiratory syndrome coronavirus | 46 |
the case of | 45 |
the structure of | 45 |
the importance of | 45 |
responsible for the | 45 |
found to be | 44 |
to investigate the | 44 |
the absence of | 44 |
the distribution of | 44 |
the mechanism of | 43 |
be used to | 43 |
the fact that | 43 |
the amino acid | 42 |
the secondary site | 42 |
according to the | 42 |
some of the | 41 |
to determine the | 41 |
of the human | 41 |
in this work | 40 |
as shown in | 40 |
amino acid sites | 40 |
located in the | 40 |
in the case | 40 |
amino acid residues | 40 |
amino acid sequence | 40 |
as a result | 39 |
the design of | 39 |
the present study | 39 |
such as the | 38 |
compared to the | 38 |
the activity of | 38 |
suggest that the | 38 |
under positive selection | 38 |
between the two | 38 |
were able to | 38 |
in the absence | 38 |
of the two | 37 |
the frad sites | 37 |
a series of | 36 |
each of the | 36 |
is based on | 36 |
most of the | 36 |
has been shown | 36 |
there is a | 36 |
canonical cleavage sites | 35 |
to be a | 35 |
shown in fig | 35 |
of amino acid | 35 |
results suggest that | 34 |
cleavage sites of | 34 |
of the cleavage | 34 |
a combination of | 34 |
consistent with the | 34 |
the location of | 33 |
at each site | 33 |
over the past | 33 |
the identification of | 33 |
in response to | 33 |
well as the | 33 |
in the caribbean | 33 |
were used to | 33 |
related to the | 33 |
show that the | 33 |
the crystal structure | 33 |
a total of | 33 |
the ability of | 32 |
and in the | 32 |
multiple sequence alignment | 32 |
the results of | 32 |
the regulation of | 32 |
site in the | 32 |
the binding of | 32 |
members of the | 32 |
is involved in | 32 |
results show that | 31 |
likely to be | 31 |
binding to the | 31 |
the analysis of | 31 |
to study the | 31 |
the function of | 31 |
were found to | 31 |
of frad sites | 31 |
of the sars | 31 |
we show that | 31 |
have shown that | 31 |
to the primary | 30 |
on the other | 30 |
function of the | 30 |
region of the | 30 |
the level of | 30 |
used as a | 30 |
are able to | 30 |
the influence of | 30 |
are involved in | 30 |
the primary site | 30 |
binding of the | 30 |
the ability to | 30 |
changes in the | 29 |
of a protein | 29 |
the most common | 29 |
a result of | 29 |
the surface of | 29 |
was supported by | 29 |
the aim of | 29 |
in the a | 29 |
of positive selection | 29 |
structural and functional | 29 |
showed that the | 29 |
of the viral | 29 |
cleavage of the | 28 |
p and p | 28 |
is required for | 28 |
of the s | 28 |
east respiratory syndrome | 28 |
end of the | 28 |
shown to be | 28 |
in which the | 27 |
positively selected sites | 27 |
residues in the | 27 |
presence of a | 27 |
at the same | 27 |
sialic acid binding | 27 |
cleavage sites in | 27 |
based on a | 27 |
a set of | 27 |
to assess the | 27 |
active site of | 27 |
was carried out | 27 |
is essential for | 27 |
of the virus | 27 |
middle east respiratory | 26 |
that can be | 26 |
a role in | 26 |
found that the | 26 |
present in the | 26 |
processing of the | 26 |
have been identified | 26 |
characterization of the | 26 |
a range of | 26 |
suggests that the | 26 |
the relationship between | 26 |
properties of the | 26 |
used in the | 26 |
to that of | 26 |
that of the | 26 |
interaction with the | 26 |
are known to | 26 |
be involved in | 26 |
found in the | 26 |
role in the | 26 |
derived from the | 26 |
sequence of the | 25 |
of the three | 25 |
the lack of | 25 |
role of the | 25 |
known to be | 25 |
the interaction between | 25 |
we were able | 25 |
the binding sites | 25 |
in the protein | 25 |
the treatment of | 25 |
the other hand | 25 |
in the same | 25 |
in complex with | 25 |
the rate of | 25 |
on the surface | 25 |
the context of | 25 |
by means of | 25 |
the top end | 25 |
of this study | 25 |
the local structures | 24 |
large number of | 24 |
we propose that | 24 |
of the p | 24 |
infectious bronchitis virus | 24 |
the wild type | 24 |
to be the | 24 |
the efficiency of | 24 |
of the n | 24 |
hepatitis c virus | 24 |
observed in the | 24 |
the binding site | 24 |
the interaction of | 24 |
influenza a virus | 24 |
site of the | 24 |
of amino acids | 23 |
supported by the | 23 |
effect of the | 23 |
the a site | 23 |
sites of the | 23 |
of the ribosome | 23 |
of the data | 23 |
was used for | 23 |
activation of the | 23 |
the cleavage sites | 23 |
positive selection in | 23 |
in the study | 23 |
an important role | 23 |
structures of the | 23 |
the end of | 22 |
insights into the | 22 |
of the coronavirus | 22 |
a and b | 22 |
the mdi spacer | 22 |
was used as | 22 |
the cleavage of | 22 |
are likely to | 22 |
interactions between the | 22 |
we developed a | 22 |
depending on the | 22 |
to understand the | 22 |
crystal structures of | 22 |
structure and function | 22 |
is an important | 22 |
the cut site | 22 |
in the present | 22 |
liu et al | 22 |
this work was | 22 |
surface coverage ratio | 21 |
to analyze the | 21 |
was found to | 21 |
the expression of | 21 |
in the active | 21 |
sites under positive | 21 |
is the most | 21 |
the detection of | 21 |
also known as | 21 |
the process of | 21 |
structure of a | 21 |
the study of | 21 |
the evolution of | 21 |
sox cut sites | 21 |
associated with the | 21 |
there is no | 21 |
total number of | 21 |
of local structures | 21 |
is known to | 21 |
identification of a | 20 |
mdi spacer use | 20 |
there was no | 20 |
in agreement with | 20 |
activity of the | 20 |
in the context | 20 |
isothermal titration calorimetry | 20 |
differences in the | 20 |
the p site | 20 |
proteolytic processing of | 20 |
its interaction with | 20 |
for the first | 20 |
used for the | 20 |
the spike protein | 20 |
features of the | 20 |
the shift site | 20 |
the impact of | 20 |
prediction of protein | 20 |
of the cell | 19 |
in our study | 19 |
wide range of | 19 |
clpro cleavage sites | 19 |
b and c | 19 |
work was supported | 19 |
proteins in the | 19 |
domain of the | 19 |
of the study | 19 |
contribute to the | 19 |
of a novel | 19 |
can be found | 19 |
position of the | 19 |
important role in | 19 |
are shown in | 19 |
of mdi spacers | 19 |
in the two | 19 |
followed by a | 19 |
results indicate that | 19 |
in the cell | 19 |
in contrast to | 19 |
the size of | 19 |
a large number | 19 |
for the design | 19 |
cleavage site in | 19 |
of the proteins | 19 |
suggested that the | 19 |
regulation of the | 19 |
molecular dynamics simulations | 18 |
characterization of a | 18 |
resulted in a | 18 |
has been used | 18 |
the structure and | 18 |
is consistent with | 18 |
predicted to be | 18 |
is used to | 18 |
is responsible for | 18 |
the potential to | 18 |
the properties of | 18 |
close to the | 18 |
a wide range | 18 |
our understanding of | 18 |
and it is | 18 |
regions of the | 18 |
of the complex | 18 |
considered to be | 18 |
acts as a | 18 |
pc cleavage site | 18 |
has also been | 18 |
amino acid sequences | 18 |
binding sites for | 18 |
which can be | 18 |
corresponding to the | 18 |
the same time | 18 |
coronavirus spike protein | 18 |
in vitro and | 18 |
a subset of | 18 |
the surface coverage | 18 |
because of the | 18 |
the basis of | 18 |
compared with the | 18 |
will be presented | 18 |
it is a | 18 |
in table s | 18 |
of the binding | 18 |
in the p | 18 |
length of the | 18 |
insight into the | 18 |
on the protein | 18 |
side of the | 18 |
addition to the | 18 |
human immunodeficiency virus | 18 |
located at the | 18 |
is able to | 18 |
increase in the | 18 |
with respect to | 18 |
due to their | 18 |
in the human | 18 |
the addition of | 18 |
binding sites of | 18 |
many of the | 18 |
of the c | 17 |
is associated with | 17 |
size exclusion chromatography | 17 |
similar to that | 17 |
have also been | 17 |
vitro and in | 17 |
our results show | 17 |
of the target | 17 |
the most important | 17 |
nuclear magnetic resonance | 17 |
in this case | 17 |
of binding sites | 17 |
we used a | 17 |
the web pages | 17 |
indicators of traditional | 17 |
to bind to | 17 |
is a key | 17 |
of influenza virus | 17 |
is composed of | 17 |
as part of | 17 |
to determine whether | 17 |
to evaluate the | 17 |
of a new | 17 |
have been developed | 17 |
we have developed | 17 |
of the other | 17 |
this suggests that | 17 |
in escherichia coli | 17 |
binding sites in | 17 |
the names of | 17 |
software distribution sites | 17 |
been found to | 17 |
and n a | 17 |
substrate specificity of | 17 |
member of the | 17 |
be due to | 17 |
the activation of | 17 |
here we present | 17 |
to have a | 17 |
at the p | 17 |
nature of the | 17 |
to predict the | 17 |
are located in | 17 |
sequence and structure | 17 |
similar to the | 17 |
the performance of | 17 |
have been shown | 17 |
the protein and | 17 |
as compared to | 17 |
binding sites on | 17 |
these results suggest | 17 |
change in the | 17 |
are responsible for | 17 |
the prediction of | 17 |
of traditional management | 17 |
the md simulations | 17 |
relative to the | 17 |
shown in table | 17 |
studies have shown | 17 |
from the md | 16 |
of influenza a | 16 |
the range of | 16 |
the dimer interface | 16 |
site and the | 16 |
all of the | 16 |
we used the | 16 |
is a major | 16 |
effect on the | 16 |
appears to be | 16 |
the host cell | 16 |
for the treatment | 16 |
it is not | 16 |
to be involved | 16 |
in combination with | 16 |
stability of the | 16 |
identified in the | 16 |
interaction between the | 16 |
it is possible | 16 |
information on the | 16 |
the affinity of | 16 |
primary binding site | 16 |
and can be | 16 |
of the ligand | 16 |
local structures and | 16 |
evolution of the | 16 |
in the sars | 16 |
of fake av | 16 |
in the development | 16 |
position in the | 16 |
of the a | 16 |
the l p | 16 |
richardson et al | 16 |
indicated that the | 16 |
included in the | 16 |
was shown to | 16 |
indicates that the | 16 |
daye et al | 16 |
the probability of | 16 |
and in vivo | 16 |
the sox cut | 16 |
due to its | 16 |
were used for | 16 |
the contribution of | 16 |
used to identify | 16 |
we showed that | 16 |
of the surface | 16 |
the amount of | 16 |
rest of the | 16 |
of the river | 16 |
use of the | 16 |
as a model | 16 |
suggesting that the | 16 |
formation of a | 16 |
the production of | 16 |
to examine the | 16 |
in the n | 16 |
we have used | 16 |
is due to | 16 |
in the top | 16 |
the concentration of | 16 |
amino acid composition | 16 |
of the local | 16 |
structural basis for | 15 |
in this paper | 15 |
to elucidate the | 15 |
half of the | 15 |
results showed that | 15 |
the processing of | 15 |
the length of | 15 |
can lead to | 15 |
and function of | 15 |
obtained from the | 15 |
surface of the | 15 |
more likely to | 15 |
we analyzed the | 15 |
binding site of | 15 |
s and s | 15 |
are based on | 15 |
the first time | 15 |
in the future | 15 |
p to p | 15 |
at the end | 15 |
to provide a | 15 |
a wide variety | 15 |
of the membrane | 15 |
putative cleavage sites | 15 |
a key role | 15 |
ribosomal protein l | 15 |
of a single | 15 |
the nature of | 15 |
we find that | 15 |
to each other | 15 |
listed in table | 15 |
the severe acute | 15 |
be used as | 15 |
majority of the | 15 |
of the peptide | 15 |
fact that the | 15 |
the degree of | 15 |
the percentage of | 15 |
affinity of the | 15 |
has not been | 15 |
in the s | 15 |
a neural network | 15 |
indicating that the | 15 |
the canonical cleavage | 15 |
the viral community | 15 |
the secondary structure | 15 |
the assembly of | 15 |
the method is | 15 |
the accuracy of | 15 |
of the recombinant | 15 |
the rest of | 15 |
which may be | 15 |
of the catalytic | 15 |
wide variety of | 15 |
of these proteins | 15 |
bind to the | 15 |
may be a | 15 |
expression of the | 15 |
some of these | 15 |
we investigated the | 15 |
of the interaction | 15 |
model of the | 15 |
the existence of | 15 |
at the c | 15 |
belongs to the | 15 |
extracted from the | 15 |
formation of the | 15 |
and characterization of | 15 |
were found in | 15 |
there was a | 15 |
the inhibition of | 14 |
the position of | 14 |
and for the | 14 |
in the past | 14 |
of the sox | 14 |
to the protein | 14 |
are capable of | 14 |
and the other | 14 |
of the main | 14 |
at least one | 14 |
was set to | 14 |
the crystal structures | 14 |
the action of | 14 |
ligand binding sites | 14 |
knowledge of the | 14 |
the composition of | 14 |
is supported by | 14 |
downstream of the | 14 |
to the secondary | 14 |
of the cut | 14 |
as previously described | 14 |
the structural and | 14 |
structural characterization of | 14 |
the ratio of | 14 |
the main river | 14 |
part of a | 14 |
with the same | 14 |
of cyber threats | 14 |
to the p | 14 |
resulted in the | 14 |
the accumulation of | 14 |
of the predicted | 14 |
the protein is | 14 |
is essential to | 14 |
the interaction with | 14 |
for the development | 14 |
the binding affinity | 14 |
the origin of | 14 |
the protein surface | 14 |
that it is | 14 |
structures and functions | 14 |
to form a | 14 |
on the basis | 14 |
it can be | 14 |
sites on the | 14 |
a measure of | 14 |
of protein structure | 14 |
indicate that the | 14 |
than that of | 14 |
thought to be | 13 |
the results show | 13 |
that there is | 13 |
a group of | 13 |
there is an | 13 |
of the mrna | 13 |
peterson et al | 13 |
of the receptor | 13 |
conformation of the | 13 |
proteins of the | 13 |
is mediated by | 13 |
the mine site | 13 |
mechanism of the | 13 |
is difficult to | 13 |
are present in | 13 |
the protein structure | 13 |
interact with the | 13 |
we also found | 13 |
revealed that the | 13 |
demma et al | 13 |
are listed in | 13 |
studies of the | 13 |
of the genome | 13 |
to the active | 13 |
divided into two | 13 |
interaction of the | 13 |
the first step | 13 |
of the proteolytic | 13 |
the stability of | 13 |
the cell surface | 13 |
is necessary for | 13 |
the barrow burn | 13 |
the course of | 13 |
information about the | 13 |
frequency per site | 13 |
to frad sites | 13 |
the kinetics of | 13 |
the sequence of | 13 |
these sites are | 13 |
differences between the | 13 |
due to a | 13 |
the application of | 13 |
transmissible gastroenteritis virus | 13 |
we have identified | 13 |
terms of the | 13 |
of the mdi | 13 |
the most abundant | 13 |
one or more | 13 |
concentration of the | 13 |
to interact with | 13 |
is likely to | 13 |
the free energy | 13 |
coronavirus infectious bronchitis | 13 |
were shown to | 13 |
to the presence | 13 |
of the active | 13 |
dependent on the | 13 |
be able to | 13 |
we believe that | 13 |
key role in | 13 |
the pol zn | 13 |
a method for | 13 |
conflict of interest | 13 |
bound to the | 13 |
methods for detecting | 13 |
at the time | 13 |
cleavage sites were | 13 |
open reading frame | 13 |
in the field | 13 |
have been reported | 13 |
play an important | 13 |
the study area | 13 |
that have been | 13 |
be used in | 13 |
been identified in | 13 |
the substrate specificity | 13 |
to understand how | 13 |
leading to the | 13 |
domain names of | 13 |
in the c | 13 |
in term of | 13 |
of which are | 13 |
light on the | 13 |
this site is | 13 |
study was to | 13 |
the sialic acid | 13 |
of the e | 13 |
the concept of | 13 |
is expected to | 13 |
the numbers of | 13 |
names of cyber | 13 |
used to determine | 13 |
and dynamics of | 13 |
the primary binding | 13 |
to explore the | 13 |
the reading frame | 12 |
the present work | 12 |
u r n | 12 |
distribution of the | 12 |
a member of | 12 |
p r e | 12 |
residues of the | 12 |
at least of | 12 |
protein structure and | 12 |
of the large | 12 |
the frequency of | 12 |
it may be | 12 |
cover per transect | 12 |
the dynamics of | 12 |
the generation of | 12 |
amino acid substitutions | 12 |
we present the | 12 |
size of the | 12 |
at least two | 12 |
of a large | 12 |
determine whether the | 12 |
of the total | 12 |
intrinsically disordered proteins | 12 |
components of the | 12 |
r n a | 12 |
upstream of the | 12 |
for each site | 12 |
small island tourism | 12 |
small number of | 12 |
o o f | 12 |
we demonstrated that | 12 |
of them are | 12 |
in relation to | 12 |
of the present | 12 |
when compared to | 12 |
is possible that | 12 |
basis for the | 12 |
of the shift | 12 |
believed to be | 12 |
the university of | 12 |
may contribute to | 12 |
affinity for the | 12 |
has been identified | 12 |
proteinase cleavage sites | 12 |
subunit of the | 12 |
this is the | 12 |
in the regulation | 12 |
we focused on | 12 |
which is a | 12 |
in the native | 12 |
shown that the | 12 |
a l p | 12 |
in site a | 12 |
l p r | 12 |
is critical for | 12 |
c and d | 12 |
is shown in | 12 |
pol zn site | 12 |
which is the | 12 |
results demonstrate that | 12 |
with the aim | 12 |
the n a | 12 |
shown in figure | 12 |
comparison of the | 12 |
of the species | 12 |
in the nucleus | 12 |
the quality of | 12 |
expressed in the | 12 |
to test whether | 12 |
n a l | 12 |
the multiple sequence | 12 |
form of the | 12 |
are the most | 12 |
previous studies have | 12 |
compared to other | 12 |
and of the | 12 |
and that the | 12 |
is important for | 12 |
we are able | 12 |
frad sites and | 12 |
the orf a | 12 |
p r o | 12 |
protein in the | 12 |
in determining the | 12 |
c and c | 12 |
o u r | 12 |
more than of | 12 |
development of a | 12 |
are associated with | 12 |
acid binding sites | 12 |
used to predict | 12 |
we hypothesize that | 12 |
r o o | 12 |
to the enzyme | 12 |
away from the | 12 |
referred to as | 12 |
central nervous system | 12 |
and cover per | 12 |
the beginning of | 12 |
be important for | 12 |
surface plasmon resonance | 12 |
which has been | 12 |
prior to the | 12 |
be found in | 12 |
it should be | 12 |
a family of | 12 |
sites that are | 12 |
the s proteasome | 12 |
mutations in the | 12 |
protein data bank | 12 |
single amino acid | 12 |
specificity of the | 12 |
by the presence | 12 |
the structures of | 12 |
characteristics of the | 12 |
is the first | 12 |
in the brain | 12 |
the emergence of | 12 |
the result of | 12 |
j o u | 12 |
the pathogenesis of | 12 |
results in the | 12 |
the exception of | 12 |
the introduction of | 12 |
by using the | 12 |
at the site | 12 |
the possibility of | 11 |
to create a | 11 |
then used to | 11 |
is thought to | 11 |
amino acid changes | 11 |
two of the | 11 |
have been found | 11 |
allowed us to | 11 |
are consistent with | 11 |
the proportion of | 11 |
evolutionary history of | 11 |
is crucial for | 11 |
dimensional structure of | 11 |
we present a | 11 |
by the clpro | 11 |
a novel coronavirus | 11 |
the overlapping region | 11 |
as in the | 11 |
linked to the | 11 |
depends on the | 11 |
were obtained by | 11 |
cover per quadrat | 11 |
potential cleavage sites | 11 |
the p position | 11 |
we have shown | 11 |
at this site | 11 |
positive selection at | 11 |
use of a | 11 |
terminal domain of | 11 |
the recombinant mbp | 11 |
the effectiveness of | 11 |
predicted to have | 11 |
the characterization of | 11 |
demonstrated that the | 11 |
secondary structure of | 11 |
it is likely | 11 |
we report the | 11 |
focused on the | 11 |
the e site | 11 |
was able to | 11 |
agreement with the | 11 |
a model of | 11 |
is that the | 11 |
of the molecular | 11 |
of these sites | 11 |
to be cleaved | 11 |
this study was | 11 |
of the substrate | 11 |
act as a | 11 |
active site and | 11 |
functionally important residues | 11 |
representation of the | 11 |
cut site in | 11 |
amino acids in | 11 |
based on their | 11 |
residues at the | 11 |
high degree of | 11 |
a model for | 11 |
is related to | 11 |
the time of | 11 |
the orf b | 11 |
sequences of the | 11 |
binding domain of | 11 |
of the first | 11 |
has been found | 11 |
we observed that | 11 |
in the binding | 11 |
difference between the | 11 |
and the c | 11 |
effects of the | 11 |
in recent years | 11 |
an example of | 11 |
sites in proteins | 11 |
positive selection and | 11 |
in line with | 11 |
this may be | 11 |
we did not | 11 |
are required for | 11 |
of the zymogen | 11 |
control of the | 11 |
be used for | 11 |
av software families | 11 |
sox cut site | 11 |
for binding to | 11 |
have been proposed | 11 |
serve as a | 11 |
in the pdb | 11 |
been used to | 11 |
in a protein | 11 |
of sites with | 11 |
medical college and | 11 |
are essential for | 11 |
of the amino | 11 |
and does not | 11 |
of tourism growth | 11 |
the synthesis of | 11 |
in the ed | 11 |
of the four | 11 |
we have been | 11 |
required for the | 11 |
removal information for | 11 |
to measure the | 11 |
proteins involved in | 11 |
profile of the | 11 |
the hd c | 11 |
van der waals | 11 |
the purpose of | 11 |
x xxy yyz | 11 |
in the second | 11 |
binding sites and | 11 |
their ability to | 11 |
pp a ab | 11 |
importance of the | 11 |
of the rna | 11 |
demonstrate that the | 11 |
university of california | 11 |
study of the | 11 |
summarized in table | 11 |
to obtain a | 11 |
of hepatitis c | 11 |
government of aruba | 11 |
mutation of the | 11 |
cleavage site of | 11 |
of protein function | 11 |
with the exception | 11 |
in a variety | 11 |
was added to | 11 |
it was shown | 11 |
that are not | 11 |
a database of | 11 |
we have also | 11 |
could be used | 11 |
similar to those | 11 |
the viral genome | 11 |
expressed in e | 11 |
proteins can be | 11 |
the release of | 11 |
associated with a | 11 |
at the n | 11 |
able to identify | 11 |
rational design of | 11 |
high levels of | 11 |
of the same | 11 |
play a role | 11 |
a method to | 11 |
an increase in | 11 |
analysis of protein | 11 |
in the data | 11 |
to be more | 11 |
the reference laboratory | 11 |
composition of the | 11 |
an analysis of | 11 |
dynamics of the | 11 |
this study is | 11 |
were detected in | 11 |
with a high | 10 |
supplementary material online | 10 |
in saccharomyces cerevisiae | 10 |
the murine coronavirus | 10 |
of proteins in | 10 |
led to the | 10 |
in our laboratory | 10 |
a highly conserved | 10 |
existence of a | 10 |
et drug sites | 10 |
more than one | 10 |
to those of | 10 |
this study we | 10 |
of the tree | 10 |
the functions of | 10 |
cover per site | 10 |
in some cases | 10 |
any of the | 10 |
of the district | 10 |
the occurrence of | 10 |
for each of | 10 |
for cyber threats | 10 |
the dissociation constant | 10 |
of sialic acid | 10 |
the distance between | 10 |
of severe acute | 10 |
resonance energy transfer | 10 |
at c for | 10 |
will be discussed | 10 |
protein interaction sites | 10 |
out of the | 10 |
focusing on the | 10 |
into account the | 10 |
of the fusion | 10 |
the past decade | 10 |
of the residues | 10 |
the large subunit | 10 |
adoption of mdi | 10 |
the probability that | 10 |
synonymous and nonsynonymous | 10 |
site loop is | 10 |
kim et al | 10 |
the intrinsically disordered | 10 |
number of the | 10 |
were identified as | 10 |
enzyme in the | 10 |
furin correction factor | 10 |
of this protein | 10 |
n d s | 10 |
data are available | 10 |
in the secondary | 10 |
sites that were | 10 |
and p sites | 10 |
is cleaved by | 10 |
cleavage sites are | 10 |
in other words | 10 |
in the process | 10 |
along with the | 10 |
we demonstrate that | 10 |
need to be | 10 |
that the binding | 10 |
in the range | 10 |
aim of the | 10 |
in the vicinity | 10 |
a protein structure | 10 |
the discovery of | 10 |
reactive oxygen species | 10 |
the human genome | 10 |
of both the | 10 |
of the sequences | 10 |
the native state | 10 |
of the sequence | 10 |
analysis of a | 10 |
of the second | 10 |
of the new | 10 |
of mdi spacer | 10 |
has been previously | 10 |
to play a | 10 |
confidence level of | 10 |
web server for | 10 |
method for the | 10 |
very close to | 10 |
primary and secondary | 10 |
studies on the | 10 |
a part of | 10 |
have not been | 10 |
was shown that | 10 |
n et al | 10 |
was based on | 10 |
in mammalian cells | 10 |
mechanism of action | 10 |
enzymatic activity of | 10 |
are thought to | 10 |
suitable sites for | 10 |
selected amino acid | 10 |
participate in the | 10 |
the data set | 10 |
plays a role | 10 |
the control of | 10 |
in the other | 10 |
structure and dynamics | 10 |
better understanding of | 10 |
is important to | 10 |
context of the | 10 |
it is also | 10 |
step in the | 10 |
ability to bind | 10 |
the folding of | 10 |
used to analyze | 10 |
for the same | 10 |
of serine proteases | 10 |
inhibition of the | 10 |
of the putative | 10 |
for the detection | 10 |
cov and sars | 10 |
the extent of | 10 |
recognition of the | 10 |
of the rbd | 10 |
it is essential | 10 |
the construction of | 10 |
were enriched in | 10 |
of the native | 10 |
multiple sequence alignments | 10 |
sites with a | 10 |
p x r | 10 |
have been described | 10 |
than in the | 10 |
a small number | 10 |
local structures are | 10 |
and on the | 10 |
to better understand | 10 |
status of the | 10 |
were identified in | 10 |
to compare the | 10 |
are predicted to | 10 |
the field of | 10 |
of the novel | 10 |
for the prediction | 10 |
to the target | 10 |
proved to be | 10 |
it is important | 10 |
influence of the | 10 |
to act as | 10 |
tourism in the | 10 |
adjacent to the | 10 |
found to bind | 10 |
of the major | 10 |
of proteins that | 10 |
it does not | 10 |
associated with this | 10 |
complex with the | 10 |
orders of magnitude | 10 |
concentrations of the | 10 |
a lack of | 10 |
our results suggest | 10 |
result of the | 10 |
family of proteins | 10 |
the hydrolysis of | 10 |
of the m | 10 |
be considered as | 10 |
to the human | 10 |
d n d | 10 |
at the molecular | 10 |
the characteristics of | 10 |
in protein structures | 10 |
may also be | 10 |
in the nt | 10 |
been proposed to | 10 |
especially in the | 10 |
scheyvens and biddulph | 10 |
expected to be | 10 |
in the formation | 10 |
this is an | 10 |
could not be | 10 |
a library of | 10 |
added to the | 10 |
in the early | 10 |
in the interaction | 10 |
this work we | 10 |
in living cells | 10 |
and may be | 9 |
is similar to | 9 |
inserted into the | 9 |
j and j | 9 |
the icu rotation | 9 |
the de novo | 9 |
in this context | 9 |
reach frad sites | 9 |
be cleaved by | 9 |
to predict protein | 9 |
is the only | 9 |
and a c | 9 |
the enzyme was | 9 |
our ability to | 9 |
are found in | 9 |
and the number | 9 |
portion of the | 9 |
were used as | 9 |
far from the | 9 |
pseudo amino acid | 9 |
new health care | 9 |
are critical for | 9 |
search results for | 9 |
international tourism demand | 9 |
the molecular basis | 9 |
c antigen sites | 9 |
which in turn | 9 |
at all sites | 9 |
in this way | 9 |
can also be | 9 |
to detect the | 9 |
to the motif | 9 |
we use the | 9 |
supplementary table s | 9 |
mouse hepatitis virus | 9 |
were carried out | 9 |
be the most | 9 |
we have found | 9 |
these results demonstrate | 9 |
to overcome the | 9 |
and p positions | 9 |
the past years | 9 |
ligand binding site | 9 |
n and d | 9 |
diversity of the | 9 |
distance between the | 9 |
alignment of the | 9 |
findings suggest that | 9 |
dependent rna polymerase | 9 |
interaction in the | 9 |
is dependent on | 9 |
nsp and nsp | 9 |
to confirm the | 9 |
of the site | 9 |
well as a | 9 |
c for h | 9 |
location of the | 9 |
structural basis of | 9 |
the recombinant protein | 9 |
and found that | 9 |
sites were predicted | 9 |
a model system | 9 |
inhibitors have been | 9 |
is a powerful | 9 |
number of patients | 9 |
wang et al | 9 |
model for the | 9 |
site at the | 9 |
to improve the | 9 |
in the literature | 9 |
sites of mers | 9 |
these frad sites | 9 |
amino acid species | 9 |
resulting in a | 9 |
cleavage sites and | 9 |
allows us to | 9 |
been shown that | 9 |
novel coronavirus from | 9 |
adaptive evolution of | 9 |
have demonstrated that | 9 |
aim of this | 9 |
binding site in | 9 |
of the spike | 9 |
been implicated in | 9 |
the s protein | 9 |
of the orf | 9 |
of the structure | 9 |
be noted that | 9 |
a high degree | 9 |
positively selected amino | 9 |
the proteolytic processing | 9 |
nt surrounding the | 9 |
is capable of | 9 |
and evolution of | 9 |
together with the | 9 |
these results indicate | 9 |
the past two | 9 |
a new coronavirus | 9 |
we note that | 9 |
only in the | 9 |
the sars coronavirus | 9 |
structural studies of | 9 |
interacts with the | 9 |
there are no | 9 |
in the crystal | 9 |
the neural network | 9 |
have the potential | 9 |
levels of the | 9 |
the amino acids | 9 |
the vicinity of | 9 |
in the yeast | 9 |
a region of | 9 |
on the web | 9 |
a single protein | 9 |
a crucial role | 9 |
orf b peptide | 9 |
the folding and | 9 |
was applied to | 9 |
and secondary structure | 9 |
for this purpose | 9 |
h and h | 9 |
binding sites are | 9 |
the order of | 9 |
of at least | 9 |
number of species | 9 |
survey of the | 9 |
in the cleavage | 9 |
were extracted from | 9 |
is represented by | 9 |
of the distribution | 9 |
to test the | 9 |
of middle east | 9 |
in the current | 9 |
mutation in the | 9 |
the mechanisms of | 9 |
the m a | 9 |
college and hospital | 9 |
in the spike | 9 |
at these sites | 9 |
lu et al | 9 |
hall and williams | 9 |
case of the | 9 |
tseng et al | 9 |
the evolutionary history | 9 |
assembly of the | 9 |
to use the | 9 |
barriers and facilitators | 9 |
the need for | 9 |
that is not | 9 |
of the sites | 9 |
a mixture of | 9 |
than the other | 9 |
to the high | 9 |
the conservation of | 9 |
h n virus | 9 |
may lead to | 9 |
in a single | 9 |
of codon substitution | 9 |
the ebola virus | 9 |
which are the | 9 |
this is consistent | 9 |
the interactions between | 9 |
and the resulting | 9 |
binding site on | 9 |
in both the | 9 |
of the l | 9 |
presence of the | 9 |
to describe the | 9 |
the cut sites | 9 |
interactions with the | 9 |
the search results | 9 |
was found in | 9 |
the family of | 9 |
terminus of the | 9 |
provided by the | 9 |
coli k genome | 9 |
abundant in the | 9 |
like cleavage site | 9 |
the hypothesis that | 9 |
and identification of | 9 |
is an essential | 9 |
the transition transversion | 9 |
the creation of | 9 |
mediated by the | 9 |
within the same | 9 |
have focused on | 9 |
li et al | 9 |
and d s | 9 |
in the first | 9 |
is likely that | 9 |
as a consequence | 9 |
that there was | 9 |
contrast to the | 9 |
the changes in | 9 |
leading to a | 9 |
from the data | 9 |
and mass spectrometry | 9 |
the resilience of | 9 |
using nmr spectroscopy | 9 |
defined as the | 9 |
we propose a | 9 |
the same as | 9 |
and c antigen | 9 |
immunodeficiency virus type | 9 |
of tourism in | 9 |
the two sites | 9 |
the ribosome and | 9 |
the total number | 9 |
molecular basis of | 9 |
conformational changes of | 9 |
as compared with | 9 |
the furin correction | 9 |
that they have | 9 |
is known about | 9 |
the domain names | 9 |
analysis showed that | 9 |
of the search | 9 |
detecting positive selection | 9 |
of our study | 9 |
amino acids and | 9 |
has been suggested | 9 |
respect to the | 9 |
positive darwinian selection | 9 |
correlated with the | 9 |
proteolytic sites in | 9 |
is located in | 9 |
it is difficult | 9 |
have found that | 9 |
of the clpro | 9 |
protein local structures | 9 |
distance from the | 9 |
the positive set | 9 |
were performed using | 9 |
the pc cleavage | 9 |
shed light on | 9 |
the red queen | 9 |
that at least | 9 |
sites are located | 9 |
data suggest that | 9 |
of the proprotein | 9 |
to be highly | 9 |
and analysis of | 9 |
used in this | 9 |
the phylogenetic tree | 9 |
by using a | 9 |
functional sites in | 9 |
department of chemistry | 9 |
of health care | 9 |
the protease activity | 9 |
seen in the | 9 |
with more than | 9 |
a serine protease | 9 |
acid sites under | 9 |
closely related to | 9 |
on the sensor | 8 |
in cancer cells | 8 |
ligand binding to | 8 |
the coronavirus infectious | 8 |
functional analysis of | 8 |
the northern territory | 8 |
comparison between the | 8 |
a confidence level | 8 |
the endoplasmic reticulum | 8 |
the enzyme in | 8 |
the dissociation constants | 8 |
could also be | 8 |
nucleic acid extraction | 8 |
past two decades | 8 |
be divided into | 8 |
was the most | 8 |
per site frequency | 8 |
for the study | 8 |
each of these | 8 |
as shown by | 8 |
mediated by a | 8 |
explanation for the | 8 |
of the pc | 8 |
of the ebola | 8 |
two binding sites | 8 |
mdi spacer adoption | 8 |
from the active | 8 |
this protein is | 8 |
as a function | 8 |
relationship between the | 8 |
by comparing the | 8 |
the significance of | 8 |
molecular determinants of | 8 |
the value of | 8 |
selection in the | 8 |
have been studied | 8 |
to calculate the | 8 |
known as the | 8 |
are expected to | 8 |
the primary and | 8 |
sequences in the | 8 |
free energies of | 8 |
cleavage site motifs | 8 |
in the cytoplasm | 8 |
binds to the | 8 |
of the correct | 8 |
free energy of | 8 |
the loss of | 8 |
the bottom of | 8 |
the dry ridge | 8 |
the catalytic domain | 8 |
was performed on | 8 |
the nt surrounding | 8 |
in the rms | 8 |
and the subsequent | 8 |
are believed to | 8 |
step of the | 8 |
in most cases | 8 |
widely used in | 8 |
is in the | 8 |
was determined by | 8 |
not yet been | 8 |
in the design | 8 |
with that of | 8 |
of the interacting | 8 |
of the host | 8 |
k genome sequence | 8 |
caused by the | 8 |
human coronavirus e | 8 |
on the structure | 8 |
the complexity of | 8 |
it was found | 8 |
degradation by the | 8 |
the web page | 8 |
only a few | 8 |
of the genetic | 8 |
we studied the | 8 |
enzyme active site | 8 |
seems to be | 8 |
new insights into | 8 |
and used to | 8 |
of the top | 8 |
data on the | 8 |
the adoption of | 8 |
has shown that | 8 |
whether or not | 8 |
note that the | 8 |
essential for the | 8 |
to the free | 8 |
these proteins are | 8 |
of this work | 8 |
for all sites | 8 |
that the majority | 8 |
target for the | 8 |
among all the | 8 |
in patients with | 8 |
nedd and nedd | 8 |
frad sites using | 8 |
secondary binding site | 8 |
floating catchment area | 8 |
are difficult to | 8 |
the specificity of | 8 |
is caused by | 8 |
belong to the | 8 |
the centre of | 8 |
ziebuhr and siddell | 8 |
based prediction of | 8 |
of protein structures | 8 |
amber force field | 8 |
of the manuscript | 8 |
role of this | 8 |
dengue virus serotype | 8 |
is the major | 8 |
of small molecules | 8 |
in the middle | 8 |
processing by the | 8 |
here we report | 8 |
the adoption process | 8 |
the amber force | 8 |
as described above | 8 |
binding affinity of | 8 |
of the h | 8 |
the department of | 8 |
resulting in the | 8 |
a amino acid | 8 |
is believed to | 8 |
of all the | 8 |
we have previously | 8 |
was found that | 8 |
state of over | 8 |
the protein to | 8 |
amino acid substitution | 8 |
cleavage site motif | 8 |
attached to the | 8 |
conformational changes in | 8 |
solution structure of | 8 |
a basis for | 8 |
for the analysis | 8 |
the association rates | 8 |
nonsynonymous and synonymous | 8 |
of sequence and | 8 |
influenza a viruses | 8 |
based on this | 8 |
used as the | 8 |
molecular mechanism of | 8 |
we searched for | 8 |
is divided into | 8 |
has the potential | 8 |
was confirmed by | 8 |
for treatment of | 8 |
simian immunodeficiency virus | 8 |
of proteins with | 8 |
be responsible for | 8 |
peptides and proteins | 8 |
is considered to | 8 |
n a and | 8 |
was mutated to | 8 |
d and e | 8 |
graduate school of | 8 |
the escherichia coli | 8 |
shown that a | 8 |
is a highly | 8 |
in cell culture | 8 |
to be important | 8 |
followed by the | 8 |
we have investigated | 8 |
were used in | 8 |
academy of sciences | 8 |
observed for the | 8 |
frad sites that | 8 |
crucial for the | 8 |
have developed a | 8 |
to be under | 8 |
those of the | 8 |
the protein data | 8 |
of the folding | 8 |
in the treatment | 8 |
is crucial to | 8 |
that has been | 8 |
the goal of | 8 |
of the method | 8 |
we have studied | 8 |
core of the | 8 |
implicated in the | 8 |
as determined by | 8 |
in case of | 8 |
the results showed | 8 |
the molecular mechanism | 8 |
that the n | 8 |
were observed in | 8 |
reveals that the | 8 |
based on these | 8 |
is found in | 8 |
focus on the | 8 |
to characterize the | 8 |
interest in the | 8 |
to test this | 8 |
the molecular level | 8 |
d n and | 8 |
small molecule inhibitors | 8 |
work was to | 8 |
of the structural | 8 |
in the new | 8 |
of this enzyme | 8 |
the ubiquitin proteasome | 8 |
the aid of | 8 |
in the substrate | 8 |
small angle x | 8 |
of the entire | 8 |
at the s | 8 |
to a new | 8 |
in the following | 8 |
context of a | 8 |
in a specific | 8 |
presence of glycans | 8 |
which could be | 8 |
necessary for the | 8 |
oseltamivir and zanamivir | 8 |
we conclude that | 8 |
health care service | 8 |
that do not | 8 |
are more likely | 8 |
the virus to | 8 |
but it is | 8 |
the fusion protein | 8 |
frequency and cover | 8 |
energies of binding | 8 |
of small island | 8 |
in eukaryotic cells | 8 |
at each position | 8 |
information for cyber | 8 |
dodds and butler | 8 |
function in the | 8 |
relative accessibility index | 8 |
many of these | 8 |
the enzyme is | 8 |
in this review | 8 |
were incubated with | 8 |
a component of | 8 |
of the short | 8 |
find that the | 8 |
gene of the | 8 |
the target protein | 8 |
the sequences of | 8 |
accounts for the | 8 |
was consistent with | 8 |
we suggest that | 8 |
of the murine | 8 |
its ability to | 8 |
to find out | 8 |
be useful in | 8 |
shows that the | 8 |
it was not | 8 |
this study were | 8 |
retrieved from the | 8 |
codon in the | 8 |
hd c site | 8 |
at room temperature | 8 |
species in the | 8 |
amino acid residue | 8 |
has been described | 8 |
we characterized the | 8 |
the central nervous | 8 |
at the reference | 8 |
in the complex | 8 |
the center of | 8 |
and in vitro | 8 |
the authors declare | 8 |
crucial role in | 8 |
a function of | 8 |
can be applied | 8 |
much of the | 8 |
critical for the | 8 |
to ensure that | 8 |
carried out using | 8 |
structures from the | 8 |
number of binding | 8 |
the degradation of | 8 |
in all cases | 8 |
frequency and abundance | 8 |
known about the | 8 |
in the multiple | 8 |
world health organization | 8 |
the search queries | 8 |
the enzymatic activity | 8 |
predicted cleavage site | 8 |
effects of over | 8 |
data not shown | 8 |
the understanding of | 8 |
terminal loop of | 8 |
has recently been | 8 |
in spite of | 8 |
proteins have been | 8 |
the influenza virus | 8 |
from the frad | 8 |
efficiency of the | 8 |
to generate the | 8 |
by the s | 8 |
molecular weight of | 8 |
the genome of | 8 |
using circular dichroism | 8 |
environment of the | 8 |
in conjunction with | 8 |
may not be | 8 |
the results obtained | 8 |
state of the | 8 |
the river alwin | 8 |
involved in a | 8 |
is used for | 8 |
a critical role | 8 |
protein structure prediction | 8 |
in comparison with | 8 |
the differences in | 8 |
protein structure alignment | 8 |
both of the | 8 |
the roles of | 8 |
to this end | 8 |
methods have been | 8 |
the transmembrane domain | 8 |
yet to adopt | 8 |
provide insight into | 8 |
that the p | 8 |
is also a | 8 |
of these two | 8 |
of the disease | 8 |
contacts between the | 8 |
although it is | 8 |
the stop codon | 8 |
the top of | 8 |
and its interaction | 8 |
which is also | 8 |
by the host | 8 |
protein can be | 8 |
in western norway | 8 |
results in a | 8 |
sox cleavage sites | 8 |
relative abundance of | 8 |
plays a key | 8 |
have investigated the | 8 |
h n influenza | 8 |
orf a peptide | 8 |
little is known | 8 |
to the s | 8 |
district medical college | 8 |
from p to | 8 |
in a given | 8 |
j is the | 8 |
to the wild | 8 |
mutations on the | 8 |
are available at | 8 |
top of the | 8 |
glutamate carboxypeptidase ii | 8 |
in close proximity | 8 |
hypothesize that the | 8 |
the conformation of | 8 |
the maturation of | 8 |
implies that the | 8 |
the terminal loop | 8 |
been summarized in | 8 |
was performed using | 8 |
to the formation | 8 |
the protein was | 8 |
of this region | 8 |
transition transversion rate | 8 |
by maximum likelihood | 7 |
plays an important | 7 |
and s a | 7 |
set of protein | 7 |
the proprotein convertases | 7 |
in the transmembrane | 7 |
is not the | 7 |
of the tourism | 7 |
in the cells | 7 |
broad range of | 7 |
of the extracellular | 7 |
the recognition of | 7 |
tool for the | 7 |
receptor and the | 7 |
downstream secondary structure | 7 |
summarized in figure | 7 |
protein interactions and | 7 |
we focus on | 7 |
type and mutant | 7 |
to be used | 7 |
could be useful | 7 |
analysis revealed that | 7 |
this indicates that | 7 |
has been reported | 7 |
and community well | 7 |
a predicted cleavage | 7 |
from frad sites | 7 |
the availability of | 7 |
able to bind | 7 |
proteins from the | 7 |
different from the | 7 |
ray crystal structure | 7 |
domains in the | 7 |
we describe the | 7 |
appear to be | 7 |
in the primary | 7 |
the short peptide | 7 |
described in sect | 7 |
secondary structure elements | 7 |
spike protein of | 7 |
as described previously | 7 |
and effects of | 7 |
b and b | 7 |
the presence or | 7 |
used to detect | 7 |
the united states | 7 |
for the presence | 7 |
rna binding site | 7 |
the results suggest | 7 |
with those of | 7 |
the features of | 7 |
to obtain the | 7 |
composed of a | 7 |
stabilization of the | 7 |
of the glycosylation | 7 |
an understanding of | 7 |
number of sites | 7 |
to increase the | 7 |
final volume of | 7 |
at this position | 7 |
catalytic domain of | 7 |
and determination of | 7 |
of one of | 7 |
with a new | 7 |
here we describe | 7 |
at least three | 7 |
specific cyber threats | 7 |
one of these | 7 |
names of frad | 7 |
gives rise to | 7 |
in presence of | 7 |
computational design of | 7 |
development of the | 7 |
folding and unfolding | 7 |
of the wild | 7 |
in the e | 7 |
about the role | 7 |
the p and | 7 |
determined to be | 7 |
have been successfully | 7 |
of the test | 7 |
the basis for | 7 |
proteolytic sites are | 7 |
to allow the | 7 |
the correlation between | 7 |
the remainder of | 7 |
in this article | 7 |
quality of life | 7 |
accuracy of the | 7 |
should be considered | 7 |
genes involved in | 7 |
at the cleavage | 7 |
has been studied | 7 |
of amyloid fibrils | 7 |
the similarity of | 7 |
tier of analysis | 7 |
have not yet | 7 |
picture of the | 7 |
spearman rank correlation | 7 |
the c terminus | 7 |
the viral rna | 7 |
of the individual | 7 |
was performed in | 7 |
located in a | 7 |
to develop a | 7 |
a multiplicative factor | 7 |
for each protein | 7 |
based on an | 7 |
amino acids with | 7 |
hydrophobic amino acids | 7 |
were subjected to | 7 |
influenza virus hemagglutinin | 7 |
positions of the | 7 |
by nmr spectroscopy | 7 |
to the same | 7 |
of the functional | 7 |
the best of | 7 |
open reading frames | 7 |
wild type and | 7 |
which results in | 7 |
the difference in | 7 |
to probe the | 7 |
a maximum of | 7 |
the enzyme activity | 7 |
also found that | 7 |
evolution of a | 7 |
better understand the | 7 |
in light of | 7 |
with or without | 7 |
and the protein | 7 |
glycans are capable | 7 |
changes in protein | 7 |
for detecting positive | 7 |
review of the | 7 |
results of our | 7 |
is achieved by | 7 |
this is a | 7 |
an overview of | 7 |
the data was | 7 |
important for the | 7 |
to the catalytic | 7 |
in the assembly | 7 |
motif in the | 7 |
binding site contacts | 7 |
action of the | 7 |
order to understand | 7 |
bottom of the | 7 |
except for the | 7 |
is comprised of | 7 |
be useful for | 7 |
enteropeptidase light chain | 7 |
encoded by the | 7 |
was identified as | 7 |
belonging to the | 7 |
with regard to | 7 |
the target proteins | 7 |
that they are | 7 |
the thermal stability | 7 |
server for the | 7 |
van der maarel | 7 |
located on the | 7 |
are in progress | 7 |
of sites under | 7 |
the ribosomal p | 7 |
of the essential | 7 |
cell entry of | 7 |
aut onoma de | 7 |
mechanism by which | 7 |
areas of the | 7 |
features of local | 7 |
an attempt to | 7 |
the cell membrane | 7 |
the combination of | 7 |
also in the | 7 |
studies indicate that | 7 |
showing that the | 7 |
zinc hook domain | 7 |
has been demonstrated | 7 |
has been proposed | 7 |
the p x | 7 |
with the highest | 7 |
between local structures | 7 |
in the catalytic | 7 |
mdi spacers in | 7 |
expressed and purified | 7 |
of the quadrat | 7 |
of the b | 7 |
at the predicted | 7 |
wake forest university | 7 |
to generate a | 7 |
effects on the | 7 |
sequences that were | 7 |
at the mine | 7 |
the arms race | 7 |
in the overlapping | 7 |
community in the | 7 |
center of the | 7 |
log likelihood scores | 7 |
of proteolytic sites | 7 |
that we have | 7 |
resolution structure of | 7 |
of s rrna | 7 |
palmeni and p | 7 |
to estimate the | 7 |
on the ribosome | 7 |
three of the | 7 |
involved in this | 7 |
were located in | 7 |
can be detected | 7 |
and binding of | 7 |
the selective pressure | 7 |
was analyzed by | 7 |
in small island | 7 |
and we have | 7 |
investigation of the | 7 |
in the evolution | 7 |
properties of these | 7 |
a final volume | 7 |
the involvement of | 7 |
in the viral | 7 |
the perch study | 7 |
of column buffer | 7 |
a class of | 7 |
should be noted | 7 |
lead to a | 7 |
acid binding site | 7 |
in the region | 7 |
with pneumonia in | 7 |
traditionally managed hay | 7 |
methods can be | 7 |
is available for | 7 |
are related to | 7 |
would like to | 7 |
of the inhibitor | 7 |
the form of | 7 |
of the sensor | 7 |
of processing at | 7 |
selected sites are | 7 |
order to investigate | 7 |
found to have | 7 |
the antigen concentration | 7 |
to reveal the | 7 |
susceptibility to infection | 7 |
in the form | 7 |
selected sites in | 7 |
was observed for | 7 |
in vitro transcription | 7 |
even in the | 7 |
and amino acid | 7 |
between the protein | 7 |
of the resulting | 7 |
residues that are | 7 |
it is therefore | 7 |
or absence of | 7 |
impact of the | 7 |
of a number | 7 |
the diversity of | 7 |
the h n | 7 |
frameshifting in the | 7 |
isolated from a | 7 |
thought to have | 7 |
even though the | 7 |
the log likelihood | 7 |
a consequence of | 7 |
the catalytic activity | 7 |
the strength of | 7 |
is characterized by | 7 |
were identified by | 7 |
and expression of | 7 |
the findings indicate | 7 |
of protein synthesis | 7 |
mcelroy and pearce | 7 |
with high affinity | 7 |
when compared with | 7 |
a and m | 7 |
leads to the | 7 |
we have designed | 7 |
as described in | 7 |
the description of | 7 |
is formed by | 7 |
of cacybp sip | 7 |
on the same | 7 |
that the l | 7 |
secondary structure and | 7 |
the potential of | 7 |
inhibitors of the | 7 |
in the laboratory | 7 |
supported by grants | 7 |
terminal amino acid | 7 |
proteins that are | 7 |
to either the | 7 |
m and m | 7 |
is known as | 7 |
the v loop | 7 |
is part of | 7 |
targets for the | 7 |
subunits of the | 7 |
at low temperatures | 7 |
of the glycan | 7 |
is not only | 7 |
proteins with a | 7 |
performance of the | 7 |
have been investigated | 7 |
had the highest | 7 |
a comparison of | 7 |
for the two | 7 |
its role in | 7 |
method has been | 7 |
proteolytic activation of | 7 |
proteins based on | 7 |
were confirmed by | 7 |
necrotic cell death | 7 |
of a human | 7 |
a and a | 7 |
processing at the | 7 |
the two proteins | 7 |
a conformational change | 7 |
cut sites that | 7 |
the group of | 7 |
to contribute to | 7 |
sites that had | 7 |
could be due | 7 |
this work is | 7 |
of e protein | 7 |
the sox cleavage | 7 |
and orf b | 7 |
we do not | 7 |
provide valuable information | 7 |
been reported to | 7 |
for prediction of | 7 |
a broad range | 7 |
presence or absence | 7 |
with the p | 7 |
mdi spacers for | 7 |
in this process | 7 |
the state of | 7 |
the usefulness of | 7 |
needs to be | 7 |
it is the | 7 |
dynamic light scattering | 7 |
maximum descent of | 7 |
to have the | 7 |
department of biochemistry | 7 |
of international tourism | 7 |
consists of a | 7 |
a reduction in | 7 |
in the sequence | 7 |
phylogenetic analysis by | 7 |
it will be | 7 |
data were collected | 7 |
cleavage at the | 7 |
of these enzymes | 7 |
the galectin fold | 7 |
details of the | 7 |
can be a | 7 |
terminal region of | 7 |
per site and | 7 |
determined by the | 7 |
functions of the | 7 |
taking into account | 7 |
analysis of these | 7 |
a decrease in | 7 |
carried out in | 7 |
the secretory pathway | 7 |
component of the | 7 |
fauna of a | 7 |
and at the | 7 |
found in both | 7 |
description of the | 7 |
with the aid | 7 |
secondary site binding | 7 |
are widely used | 7 |
a phylogenetic tree | 7 |
of protein folding | 7 |
of the f | 7 |
collection and analysis | 7 |
this type of | 7 |
on the mine | 7 |
diseases such as | 7 |
none of the | 7 |
been associated with | 7 |
using a combination | 7 |
the name of | 7 |
protein is a | 7 |
action of a | 7 |
and molecular dynamics | 7 |
serine protease inhibitors | 7 |
the host plant | 7 |
an intrinsically disordered | 7 |
framework for the | 7 |
helix of the | 7 |
this can be | 7 |
in the different | 7 |
lee et al | 7 |
is synthesized as | 7 |
of the northern | 7 |
as frad sites | 7 |
cov and mers | 7 |
of a highly | 7 |
the solution structure | 7 |
this model is | 7 |
and inhibition of | 7 |
that there are | 7 |
we decided to | 7 |
leads to a | 7 |
in vitro studies | 7 |
of functional sites | 7 |
structural features of | 7 |
in the extracellular | 7 |
in contrast with | 7 |
were introduced into | 7 |
was performed by | 7 |
in a large | 7 |
glycosylation sites in | 7 |
the molecular mechanisms | 7 |
feature of the | 7 |
aim is to | 7 |
contributed to the | 7 |
implications for the | 7 |
of the effect | 7 |
of healthcare facilities | 7 |
of the protease | 7 |
using the same | 7 |
to minimize the | 7 |
health care services | 7 |
the s rrna | 7 |
of the glycans | 7 |
results of this | 7 |
order to find | 7 |
transect frequency per | 7 |
de novo design | 7 |
that the presence | 7 |
impact on the | 7 |
the binding kinetics | 7 |
in the late | 7 |
the prevalence of | 7 |
both in vitro | 7 |
the most prevalent | 7 |
observed that the | 7 |
the immune system | 7 |
the proteolytic site | 7 |
frad sites in | 7 |
seen in figure | 7 |
transcription and translation | 7 |
after h of | 7 |
in the site | 7 |
by furin and | 7 |
is in agreement | 7 |
analysis by maximum | 7 |
identification of the | 7 |
they do not | 7 |
the study was | 7 |
we are currently | 7 |
the results from | 7 |
with each other | 7 |
a cleavage site | 7 |
the fraction of | 7 |
at site and | 7 |
the ligand binding | 7 |
cleaved by furin | 7 |
the human coronavirus | 7 |
is a member | 7 |
distant from the | 7 |
its interactions with | 7 |
a new method | 7 |
the core of | 7 |
bovine serum albumin | 7 |
is expressed in | 7 |
most of these | 7 |
of the virome | 7 |
to form the | 7 |
at specific locations | 7 |
strongly associated with | 7 |
and the role | 7 |
that could be | 7 |
to the n | 7 |
was the first | 7 |
of the heptamer | 7 |
findings indicate that | 7 |
under purifying selection | 7 |
to make the | 7 |
scores for the | 7 |
was observed in | 7 |
sites from the | 7 |
mapping of the | 7 |
the need to | 7 |
in the dimer | 7 |
the association rate | 7 |
in the wild | 7 |
of cleavage sites | 7 |
have the same | 7 |
syndrome coronavirus spike | 6 |
are in agreement | 6 |
were applied to | 6 |
use land cover | 6 |
were analyzed using | 6 |
structure of this | 6 |
sequence and the | 6 |
likely to have | 6 |
to have originated | 6 |
detected most often | 6 |
for the sars | 6 |
are crucial for | 6 |
confined to the | 6 |
the catalytic triad | 6 |
the difference between | 6 |
for the top | 6 |
may be involved | 6 |
for the identification | 6 |
the united nations | 6 |
influenza virus a | 6 |
furin and other | 6 |
by a combination | 6 |
results presented here | 6 |
the proteolytic regulation | 6 |
the modulation of | 6 |
the bottom fauna | 6 |
is needed to | 6 |
was expressed in | 6 |
formed in the | 6 |
are important for | 6 |
kinetic parameters of | 6 |
to search for | 6 |
the ace receptor | 6 |
fraction of the | 6 |
a target for | 6 |
and development of | 6 |
phlebophylla and s | 6 |
the boat conformation | 6 |
regions in the | 6 |
the s ribosome | 6 |
in the lower | 6 |
with the binding | 6 |
research for child | 6 |
to a more | 6 |
of the d | 6 |
higher than that | 6 |
it to be | 6 |
because they are | 6 |
dna and rna | 6 |
early adopter sites | 6 |
we are developing | 6 |
a new model | 6 |
consequence of the | 6 |
the occupancy status | 6 |
to catalyze the | 6 |
possible that the | 6 |
was associated with | 6 |
this method is | 6 |
to participate in | 6 |
were designed to | 6 |
of protein surface | 6 |
health care facilities | 6 |
the cleavage sequences | 6 |
was then used | 6 |
based on our | 6 |
of the reaction | 6 |
available in the | 6 |
in the positive | 6 |
virus and host | 6 |
a distance of | 6 |
as a protein | 6 |
selection in a | 6 |
the native structure | 6 |
a mutant of | 6 |
in less than | 6 |
the relative abundance | 6 |
crystal structures and | 6 |
detected in the | 6 |
remainder of the | 6 |
jones et al | 6 |
such as those | 6 |
of a variety | 6 |
subcellular localization of | 6 |
a hybrid model | 6 |
of the results | 6 |
tourism from a | 6 |
terminal to the | 6 |
c and pol | 6 |
the river coquet | 6 |
in the us | 6 |
modulation of the | 6 |
in an attempt | 6 |
orf a and | 6 |
lower than that | 6 |
are indicated by | 6 |
web pages and | 6 |
in the control | 6 |
secondary and tertiary | 6 |
a new host | 6 |
accessed the curriculum | 6 |
the main protease | 6 |
present study was | 6 |
the catalytic efficiency | 6 |
previously shown that | 6 |
the full length | 6 |
of the domain | 6 |
the determinants of | 6 |
in comparison to | 6 |
binding site is | 6 |
the gene encoding | 6 |
a significant difference | 6 |
the potential for | 6 |
access to healthcare | 6 |
was predicted to | 6 |
the product of | 6 |
the avian na | 6 |
and orf a | 6 |
at the centre | 6 |
is very important | 6 |
from each of | 6 |
by the viral | 6 |
one of which | 6 |
is performed by | 6 |
in the number | 6 |
of the kexin | 6 |
m a in | 6 |
site directed mutagenesis | 6 |
the absence or | 6 |
selection on the | 6 |
have resulted in | 6 |
in human brain | 6 |
as previously reported | 6 |
of dengue virus | 6 |
the decision to | 6 |
of the peptides | 6 |
contribution to the | 6 |
of ebola virus | 6 |
on the right | 6 |
of the gene | 6 |
ability of the | 6 |
cell wall binding | 6 |
of protein aggregation | 6 |
how to remove | 6 |
basis of the | 6 |
the results indicate | 6 |
on amino acid | 6 |
introduced into the | 6 |
immune response to | 6 |
a cluster of | 6 |
it is clear | 6 |
and that this | 6 |
and the active | 6 |
quadrat frequency per | 6 |
used to evaluate | 6 |
aspects of the | 6 |
to reduce the | 6 |
in the americas | 6 |
occupancy status of | 6 |
play a crucial | 6 |
of a given | 6 |
gr and tif | 6 |
the substrate binding | 6 |
growth in the | 6 |
figure a and | 6 |
of h n | 6 |
were obtained from | 6 |
between these two | 6 |
the complement system | 6 |
active site is | 6 |
sites and the | 6 |
a powerful tool | 6 |
only of the | 6 |
the catalytic cysteine | 6 |
the rna polymerase | 6 |
of the codon | 6 |
in a wide | 6 |
a web server | 6 |
and it has | 6 |
was designed to | 6 |
the human brain | 6 |
of both proteins | 6 |
in collaboration with | 6 |
most abundant and | 6 |
simulations were run | 6 |
the response of | 6 |
the mutation of | 6 |
sars and sars | 6 |
the secondary binding | 6 |
processed by furin | 6 |
to min post | 6 |
the gfp mrna | 6 |
based on protein | 6 |
method to predict | 6 |
were in the | 6 |
interpretation of the | 6 |
of adaptive evolution | 6 |
the unfolded state | 6 |
chen et al | 6 |
the positively selected | 6 |
at the surface | 6 |
in the sites | 6 |
trained to identify | 6 |
the reaction of | 6 |
at that site | 6 |
for the second | 6 |
domain and the | 6 |
should not be | 6 |
sites using the | 6 |
have been used | 6 |
the kinetic parameters | 6 |
sequence at the | 6 |
myelin basic protein | 6 |
were excluded from | 6 |
creative commons attribution | 6 |
host cell proteases | 6 |
tested whether the | 6 |