bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
zika virus	1622
study design	529
case studies	483
background case	481
zikv infection	391
design method	387
results finding	375
virus infection	356
public health	190
blood bank	188
red blood	176
ns pro	169
pregnant women	162
whole blood	156
results findings	144
design methods	138
blood donors	137
ebola virus	135
sexual transmission	134
west nile	124
dengue virus	118
blood center	118
natural products	112
infectious diseases	104
nile virus	103
blood cells	102
blood products	101
respiratory syndrome	99
united states	95
red cell	93
blood cell	92
viral rna	88
blood group	87
zika ns	85
infectious disease	81
blood components	79
vertical transmission	79
yellow fever	78
aedes aegypti	76
rbc units	76
mg dl	74
virus disease	74
transfusion medicine	73
blood transfusion	72
immune response	71
vero cells	70
clinical trials	70
spinal cord	67
blood product	67
vaccine development	66
transfusion service	65
infected cells	63
zikv rna	62
neutralizing antibodies	62
flow cytometry	61
middle east	61
french polynesia	61
performed using	60
blood donor	57
health organization	57
type i	56
medical center	56
blood donation	56
doc id	55
cord uid	55
room temperature	54
transfusion reactions	54
antibody screen	54
rhce ce	54
mouse model	54
east respiratory	54
congenital zika	53
stem cell	52
antiviral activity	52
emerging infectious	51
ng ml	51
world health	50
zikv strains	50
health care	49
nucleic acid	48
acute respiratory	48
platelet count	48
viral loads	47
viral replication	46
animal models	46
red cells	46
center background	46
significantly higher	46
viral infections	46
nervous system	46
birth defects	45
massive transfusion	45
severe acute	45
neutralizing antibody	45
quality control	44
motor deficits	44
virus transmission	44
nk cells	43
virus replication	43
abo rh	43
immune responses	43
virus outbreak	43
viral load	43
blood centers	42
zika fever	42
testicular tissue	42
ag mice	42
blood donations	42
peripheral blood	42
risk factors	41
days post	41
statistically significant	41
cell culture	41
positive samples	40
monoclonal antibodies	40
syndrome coronavirus	40
significant difference	40
pathogen reduction	40
viral genome	40
zika syndrome	40
south america	39
viral genomes	39
body weight	39
chikungunya virus	39
stem cells	39
clinically significant	39
blood samples	38
may also	38
blood type	38
rbc transfusion	38
blood supply	37
patient care	37
zikv replication	37
central nervous	37
er stress	37
genome sequencing	37
mosquito bites	37
zika infection	36
systematic review	36
red cross	36
apheresis platelets	36
blood services	36
clinical trial	35
immune cells	35
endothelial cells	35
cerebrospinal fluid	35
infected individuals	35
virus infections	34
pregnant mice	34
cell death	34
global health	34
natural product	34
virus vaccine	34
zika outbreak	34
deep sequencing	34
sickle cell	34
inhibitory activity	34
blood loss	34
viral infection	34
blood volume	33
influenza virus	33
amniotic fluid	33
adverse events	33
virus zika	33
previously described	33
dna vaccine	32
way anova	32
japanese encephalitis	32
antibody titers	32
within hours	32
previously reported	32
significant differences	31
aegypti mosquitoes	31
rhesus macaques	31
innate immune	31
infected mice	31
medical record	31
disease control	30
dnk cells	30
patient blood	30
cd cells	29
mg kg	29
zika viruses	29
spectrum antiviral	29
copies ml	29
transfusion vol	29
transfusion reaction	29
zikv challenge	29
molecular testing	29
virus rna	28
generation sequencing	28
target enrichment	28
zika vaccine	28
total number	28
health emergency	28
yap island	28
fetal interface	28
avian influenza	28
plasma exchange	28
aedes mosquitoes	28
viral diseases	27
blood banks	27
hemolytic transfusion	27
patient samples	27
fever virus	27
symptom onset	27
west africa	27
results suggest	27
breast milk	27
transfusion services	27
treated mice	27
blood management	27
vector control	27
immune system	27
reverse transcription	27
cell lines	27
virus associated	26
phase i	26
one year	26
cell disease	26
high titer	26
blood component	26
zikv inoculation	25
ic values	25
cell types	25
antibody identification	25
monoclonal antibody	25
adverse effects	25
barre syndrome	25
optimal control	25
american red	25
reproductive number	25
zikv strain	25
puerto rico	25
zikv mr	25
patient safety	25
weight loss	25
drug resistance	24
flow cytometric	24
month period	24
year old	24
bone marrow	24
lethal mutagenesis	24
zikv proteins	24
motor neurons	24
host cell	24
live attenuated	24
electronic medical	24
bact alert	24
positive results	24
zikv ns	23
algan gan	23
platelet concentrates	23
human population	23
virus pathogenesis	23
endoplasmic reticulum	23
encephalitis virus	23
class i	23
pro complexes	23
test results	23
analyzed using	23
two different	23
blood safety	23
data sharing	23
neutralizing activities	23
results showed	23
zika transmission	23
vaccine candidates	23
thermo fisher	23
body fluids	23
human immunodeficiency	22
storage containers	22
platelet counts	22
serum samples	22
first trimester	22
study period	22
units transfused	22
cell line	22
male mice	22
aedes albopictus	22
see table	22
transfusion practice	22
ebola outbreak	22
dependent enhancement	22
one health	22
ns protease	22
clinical practice	22
international concern	22
false positive	22
three times	22
virus genome	22
information system	22
inflammatory response	22
significantly different	22
pregnancy outcomes	22
cord blood	21
immunodeficiency virus	21
reference laboratory	21
new york	21
least one	21
virus ns	21
endemic areas	21
virus infects	21
donor center	21
regional blood	21
fruit bats	21
real time	21
sexually transmitted	21
human cytomegalovirus	21
emergency department	21
frozen plasma	21
animal model	21
hemolytic anemia	21
birth weight	21
increased risk	21
hong kong	21
intensive care	20
serologic testing	20
zika forest	20
platelet products	20
cell viability	20
zikv diagnostics	20
scd patients	20
zikv ediii	20
inventory management	20
case report	20
per month	20
case study	20
iu ml	20
pandemic influenza	20
life cycle	20
retrospective study	20
time pcr	20
basic reproductive	20
plasma samples	20
transfusion protocol	20
dengue fever	20
statistical significance	20
trauma patients	20
disease outbreaks	20
time period	20
antibody response	20
present study	20
significantly lower	20
rna viruses	20
mayo clinic	20
control measures	20
per year	20
bacterial contamination	20
transmission dynamics	19
peer review	19
human infection	19
platelet inventory	19
cells infected	19
envelope protein	19
host immune	19
incubation period	19
pro complex	19
commercially available	19
disease transmission	19
neutralizing activity	19
time points	19
apheresis platelet	19
i interferon	19
preterm birth	19
dengue viruses	19
plasma units	19
log copies	19
well plates	19
lumbosacral spinal	19
des cas	19
therapeutic plasma	19
saudi arabia	19
rhd gene	19
cd deficiency	19
samples tested	19
canadian blood	19
deferral rates	19
blood collection	19
virus type	18
mice treated	18
amino acid	18
treated cells	18
virus isolate	18
zikv infections	18
rare donor	18
rbc transfusions	18
risk factor	18
antiviral activities	18
low birth	18
neurological complications	18
water storage	18
dengue vaccine	18
borne transmission	18
shelf life	18
federated states	18
patients received	18
hospital transfusion	18
statistical analysis	18
university hospital	18
national blood	18
platelet transfusion	18
zikv activity	18
evaluated using	18
platelet units	18
next generation	18
antigen expression	18
risk assessment	18
first time	18
usutu virus	18
significantly increased	17
high levels	17
borne diseases	17
monoclonal anti	17
total rna	17
immunosuppressed mice	17
latin america	17
donor screening	17
neural stem	17
human placental	17
serological specificity	17
human monoclonal	17
rhd beadchip	17
host cells	17
sertoli cells	17
type ii	17
zika epidemic	17
treated rbcs	17
small number	17
hospital background	17
plaque assay	17
intrauterine infection	17
pathogen inactivation	17
rejuvenation solution	17
virus particles	17
female donors	17
emerging viral	17
severe disease	17
eu eea	17
negative control	17
ediii protein	17
vitro quality	17
hcmv infection	17
congenital anomalies	17
blood ordering	17
first isolated	17
iron deficiency	17
west african	17
new automated	16
jamaican fruit	16
novel coronavirus	16
viral proteins	16
solid phase	16
tube testing	16
herpes simplex	16
widely used	16
vaccine design	16
pfu ml	16
manual tube	16
progenitor cells	16
literature review	16
nk cell	16
fetal brain	16
inhibit zikv	16
viral entry	16
zika igg	16
antibody screening	16
neural progenitor	16
case series	16
genital tract	16
virus epidemic	16
two groups	16
blood service	16
serial dilutions	16
genomic dna	16
clinical outcomes	16
infected patients	16
serially diluted	16
two independent	16
tertiary care	16
volume reduction	16
control study	16
placental barrier	16
repeat testing	16
cell responses	16
within days	16
leucocyte depleted	16
high prevalence	16
neural progenitors	16
pediatric patients	16
blood system	16
fresh frozen	16
donor samples	16
zikv transmission	16
brain endothelial	16
even though	16
white blood	15
human skin	15
vaccine platforms	15
dtt treatment	15
authors declare	15
endemic regions	15
stored rbcs	15
antiglobulin test	15
membrane fusion	15
voluntary blood	15
phase iii	15
high electron	15
protective efficacy	15
additive solution	15
pregnant woman	15
cd cd	15
olfactory ensheathing	15
marburg virus	15
unfolded protein	15
vast majority	15
asian lineage	15
phylogenetic analysis	15
clinical studies	15
mosquito species	15
hematopoietic stem	15
patients receiving	15
also known	15
genomic data	15
chain reaction	15
future studies	15
negative blood	15
phase ii	15
rbcs stored	15
ns protein	15
vaccine candidate	15
emerging viruses	15
aedes mosquito	15
fetal demise	15
rbc unit	15
strain prvabc	15
brazil zika	15
specific mabs	15
significant increase	15
graphpad prism	15
infects human	15
ferritin levels	15
neurological disorders	15
virus detection	15
cell cultures	15
terumo bct	15
low levels	15
mrna vaccines	15
likely due	15
antiviral agents	15
reagent red	15
rna copies	15
fisher scientific	15
polymerase chain	15
large number	15
mouse models	15
drug administration	15
rhesus macaque	15
rhd diiia	15
logistic regression	15
implementing partners	15
crystal structure	15
electron mobility	15
natural vertical	15
amotosalen uva	15
rhesus monkeys	15
infectious zika	15
control strategies	14
emergency blood	14
fda approved	14
significant antibodies	14
zikv neonates	14
retrospective review	14
turnaround time	14
whole genome	14
sierra leone	14
syndrome outbreak	14
hemolytic disease	14
buffy coat	14
viral particles	14
best practices	14
independent experiments	14
treated zikv	14
blood systems	14
virus strain	14
health system	14
iron metabolism	14
tissue tropism	14
emergency release	14
zika cases	14
viral pathogens	14
nucleic acids	14
dexamethasone immunosuppression	14
adverse pregnancy	14
blood transfusions	14
zika vrna	14
dengue ns	14
reverse transcriptase	14
flaviviral ns	14
significant impact	14
cytomegalovirus infection	14
inhibits zika	14
donor population	14
hemoglobin levels	14
sciatic nerve	14
human serum	14
male donors	14
direct antiglobulin	14
vaccine clinical	14
linear regression	14
tube method	14
developing fetus	14
care providers	14
may affect	14
rapid spread	14
infection zika	14
human neutralizing	14
negative rbcs	14
human primates	14
severe neurological	14
quality improvement	14
primary human	14
salivary gland	14
neg rbc	14
blood screening	14
antibody screens	14
inhibit zika	14
pathogen reduced	14
rna replication	14
rbc products	14
specific antibody	14
tested positive	14
comparator assay	14
spinal motor	14
outbreak associated	14
gan high	14
breast cancer	14
human plasma	14
zikv ir	14
pathogen surveillance	14
resistant variants	14
utr regions	14
serum albumin	13
protein expression	13
care unit	13
transfusion transmitted	13
protein response	13
genetic variants	13
metagenomic sequencing	13
congenital infection	13
single unit	13
standard deviation	13
genotyping results	13
chloroquine treatment	13
antiviral drugs	13
university school	13
trauma center	13
healthy adults	13
first report	13
rna virus	13
i ii	13
average number	13
like activity	13
dna sequencing	13
ebola epidemic	13
pluripotent stem	13
low ferritin	13
phenyl ring	13
clinical samples	13
different cell	13
infectious virus	13
inhibits zikv	13
days later	13
viral pandemics	13
tested using	13
mononuclear cells	13
one unit	13
motor cortex	13
side effects	13
storage lesion	13
intrauterine infections	13
donated blood	13
irradiated blood	13
confirmed positive	13
congenital malformations	13
standard tube	13
forming units	13
positive control	13
adverse reactions	13
simplex virus	13
hla antibodies	13
phase clinical	13
stress granules	13
strains tested	13
similar results	13
endemic equilibrium	13
cost savings	13
one patient	13
clinical symptoms	13
one study	13
commonly used	13
transfusion testing	13
final concentration	13
human igg	13
cell transplantation	13
one hour	13
rhd genotyping	13
transfused patients	13
laboratory testing	13
trophoblast cells	13
sperm count	13
per unit	13
purified inactivated	13
virus entry	13
based transfusion	12
replacement fluid	12
mosquito populations	12
asymptotically stable	12
nat yield	12
patient population	12
high risk	12
patients undergoing	12
disease prevention	12
results indicate	12
years old	12
local transmission	12
genome replication	12
health authorities	12
interferon signaling	12
western hemisphere	12
group system	12
hbv dna	12
rna polymerase	12
cells may	12
brain barrier	12
per patient	12
borne viruses	12
thawed plasma	12
sars coronavirus	12
seminiferous tubules	12
altered infectivity	12
hcmv infected	12
human health	12
clinical development	12
reproduction number	12
control group	12
disease surveillance	12
preventive behaviors	12
academic medical	12
umbilical cord	12
structural proteins	12
blood supplier	12
positive cells	12
antigen negative	12
possible association	12
study zika	12
clinically relevant	12
predicted phenotype	12
time course	12
pan american	12
mutation frequencies	12
using two	12
central america	12
kir ds	12
pilot study	12
syncytial virus	12
hcv rna	12
respiratory syncytial	12
false negative	12
blood sample	12
rhd negative	12
buffered saline	12
american health	12
congenital zikv	12
neutralizing mabs	12
vps score	12
lessons learned	12
hemorrhagic fever	12
log ec	12
based blood	12
human brain	12
high throughput	12
er membrane	12
based vaccines	12
protein folding	12
analysis revealed	12
better understand	12
immature platelet	12
enveloped viruses	12
inhibited zikv	12
old female	12
management system	12
ml kg	12
dendritic cells	12
alloimmunized patients	12
ion torrent	12
family members	12
transfusion recipients	12
also tested	12
virus strains	12
cells ml	12
clinical manifestations	12
affected areas	12
hospital blood	12
reactive samples	12
genomic epidemiology	12
donate blood	12
case reports	12
rhesus monkey	12
rhd weak	12
hours post	12
sanger sequencing	12
regression analysis	12
bodily fluids	12
pandemic preparedness	11
vector competence	11
southeast asia	11
zikv may	11
cd cell	11
antigen typing	11
study demonstrated	11
working group	11
neutralize zikv	11
virus may	11
recent studies	11
plt count	11
emergency use	11
samples collected	11
neuroglial cells	11
disease outbreak	11
dpg levels	11
retrospective analysis	11
facs buffer	11
untranslated regions	11
african americans	11
antibody titer	11
human cases	11
prevent zika	11
host factors	11
high frequency	11
dna polymerase	11
compatible blood	11
critically ill	11
antibody responses	11
virus titers	11
like illness	11
hydrogen bond	11
different time	11
automated bp	11
perinatal transmission	11
apheresis donors	11
transfusion safety	11
multiple comparison	11
viral wgs	11
may occur	11
much lower	11
within weeks	11
buffy coats	11
split rate	11
cohort study	11
structural basis	11
abo typing	11
zikv compound	11
response rate	11
post thaw	11
calculated based	11
man bsaas	11
crystal violet	11
three days	11
technician related	11
human mabs	11
ensheathing cells	11
prospective study	11
phone calls	11
cxcr pd	11
human cd	11
cell migration	11
important role	11
zikv infected	11
significantly reduced	11
rights reserved	11
may help	11
dependent manner	11
determined using	11
disease epidemics	11
kindly provided	11
mean age	11
among blood	11
patient harm	11
large volume	11
larvae pools	11
nip rhd	11
plasma replacement	11
titer anti	11
epithelial cells	11
may provide	11
new world	11
preprint posting	11
among men	11
viral sequences	11
donor plasma	11
hb deferral	11
tissue culture	11
cd tregs	11
unfolded proteins	11
specificity zika	11
breeding sites	11
patients requiring	11
hematology analyzer	11
transplant recipients	11
multiple myeloma	11
human coronavirus	11
zikv outbreak	11
automated alinity	11
may include	11
hod otii	11
platelet transfusions	11
persistent infection	11
differential equations	11
google trends	11
limited data	11
determine whether	11
denv infection	11
human neural	11
inhibitory effects	11
plaque reduction	11
molecular weight	11
flaviviridae family	11
gastrocnemius muscle	11
rh typing	11
course study	11
reference laboratories	11
cell processor	11
ab plasma	11
antenatal care	11
human transmission	11
virus dna	11
diagnostic tests	11
influenza viruses	11
antiviral agent	11
developing fetuses	11
health emergencies	11
tranexamic acid	11
iron depletion	11
interferon treatment	11
strain pan	11
zika pandemic	11
recent years	11
cell units	11
electron microscopy	10
wide range	10
time point	10
platelet recovery	10
fatality rate	10
hindlimb motor	10
donor unit	10
mass spectrometry	10
abo bw	10
rbc alloimmunization	10
virus challenge	10
coinfected mosquitoes	10
last years	10
gene sequences	10
result verification	10
titer results	10
micronesia zika	10
weeks old	10
data management	10
measured using	10
hydroxyl group	10
controlled trial	10
several studies	10
studies showed	10
pacific islands	10
febrile illness	10
away time	10
current status	10
bovine serum	10
study demonstrates	10
maternal immune	10
pathogenic mutations	10
borne virus	10
data suggest	10
first described	10
also observed	10
potent neutralizing	10
rbc alloantibodies	10
limited number	10
baby units	10
data collection	10
zkv testing	10
us blood	10
global spread	10
per week	10
female mice	10
packed red	10
digital epidemiology	10
creative commons	10
blood pressure	10
three different	10
flavivirus infection	10
blood groups	10
mers coronavirus	10
sample collection	10
see note	10
reproductive tract	10
human strains	10
positive antibody	10
peg iat	10
replication cycle	10
htlv i	10
laboratory data	10
rna extraction	10
duke university	10
mosquito vectors	10
patient received	10
artificial intelligence	10
health surveillance	10
listeria monocytogenes	10
may lead	10
high specificity	10
asian genotype	10
zikv envelope	10
significantly decreased	10
ill patients	10
inactivated zika	10
infants born	10
detection limit	10
viral vectors	10
stored rbc	10
slightly higher	10
novel antiviral	10
zikv particles	10
antiviral drug	10
storage period	10
ttp patients	10
serologic weak	10
may require	10
zikv isolates	10
patients may	10
virus ebola	10
study aimed	10
sciatic notch	10
cross blood	10
viral disease	10
five days	10
mobility transistors	10
acute phase	10
blood specimens	10
reduced zikv	10
wbc count	10
mosquito bite	10
antibodies isolated	10
infection may	10
tissue sections	10
testing using	10
histological analysis	10
rhd xt	10
open access	10
also performed	10
drug development	10
family planning	10
chart review	10
days prior	10
early stages	10
blood banking	10
tissue factor	10
different zikv	10
congenital cytomegalovirus	10
coronavirus disease	10
new process	10
stranded rna	10
national institutes	10
crossmatch compatible	10
median age	10
dans un	10
way valve	10
also used	10
dans les	10
immunohematology reference	10
cell receptor	10
microcephaly cases	10
endemic countries	10
i interferons	10
er lumen	10
two days	10
negative results	10
zika prevention	10
product wastage	10
childbearing age	10
medicine background	10
cd expression	10
closely related	10
medical records	10
semen samples	10
ap donors	10
patients presenting	10
clinical metagenomics	10
life technologies	10
id rhd	10
apheresis procedures	10
donor program	10
vertically transmitted	10
spectra optia	10
single dose	10
patient identification	10
post collection	10
dengue infection	10
chronically transfused	10
gene sequencing	10
protein kinase	10
pcr products	10
control mice	10
lymph nodes	10
day post	10
interim guidance	10
igg antibody	10
rbc storage	10
single donor	10
may result	10
five flavonoids	10
binding sites	10
fresenius kabi	10
dna vaccines	10
complete genome	10
vector transmission	10
therapeutic potential	10
acute infection	10
platelet additive	10
research institute	10
complete protection	10
virus particle	10
hla class	10
preventive measures	10
com scientificreports	10
using standard	10
unlinked zika	10
ninds nih	10
infectious titer	9
transfusion practices	9
blood order	9
previous study	9
study days	9
week period	9
units per	9
ortho clinical	9
prostate cancer	9
delayed hemolytic	9
inventory levels	9
les mesures	9
laboratory information	9
infection rate	9
health concern	9
mice zika	9
significant reduction	9
comparison tests	9
modelling study	9
final product	9
specific antigen	9
influenza pandemic	9
nat screening	9
platelet adhesion	9
much higher	9
clinical outcome	9
may contribute	9
du virus	9
second sample	9
cells kg	9
natural killer	9
basic reproduction	9
informed consent	9
immucor neo	9
outbreak response	9
surgical blood	9
pandemic potential	9
seasonal influenza	9
within normal	9
low titer	9
genome sequence	9
year period	9
mathematical model	9
suckling mice	9
cmap amplitudes	9
cell surface	9
motor neuron	9
fold increase	9
human pregnancy	9
routine quality	9
candida spp	9
first case	9
neutralizing monoclonal	9
spondweni virus	9
paper sensor	9
liver disease	9
copies per	9
based sensors	9
screening test	9
plasma volume	9
binding affinity	9
lassa fever	9
natural infection	9
plaque forming	9
observational study	9
phase red	9
culture media	9
terminal residues	9
clinical data	9
cases reported	9
rhd variant	9
trima accel	9
gestational age	9
infected mothers	9
another study	9
medium containing	9
laboratory operations	9
bacterial culture	9
candidate vaccines	9
potential benefits	9
three patients	9
two cases	9
safe blood	9
general population	9
treated group	9
exact test	9
first reported	9
women infected	9
human antibody	9
per day	9
par le	9
blood count	9
hla typing	9
pg ml	9
long term	9
protein synthesis	9
high incidence	9
time rt	9
also reported	9
transmembrane protein	9
democratic republic	9
virus genomes	9
binding domain	9
allogeneic blood	9
clone anti	9
patient outcomes	9
improve patient	9
genus flavivirus	9
clinical presentation	9
samples obtained	9
yap state	9
using different	9
mesenchymal stem	9
randomized controlled	9
germ cells	9
kidney transplant	9
failed runs	9
hla antibody	9
first months	9
indirect antiglobulin	9
competing interests	9
two additional	9
cortical neural	9
factor viii	9
mhc class	9
molecular mechanisms	9
thrombocytopenic purpura	9
age group	9
blood derived	9
pcr detection	9
studies will	9
laboratories indicated	9
probable non	9
expression levels	9
maculopapular rash	9
zika outbreaks	9
steady state	9
heavy chain	9
platelet collections	9
willebrand factor	9
cell collection	9
aegypti mosquito	9
rhce cehar	9
hsqc peaks	9
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brazilian zika	9
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south korea	9
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viral vector	9
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weeks among	9
sexual contact	9
positive dat	9
rbc antigens	9
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may become	9
clinical signs	9
nucleoside analogues	9
active site	9
liquid plasma	9
among women	9
recent outbreaks	9
uninfected cells	9
teg results	9
disease caused	9
positive donations	9
clinical diagnostics	9
adverse outcomes	9
zikv epidemic	9
organ transplant	9
septic transfusion	9
north america	9
viral nucleic	9
normal limits	9
innate immunity	9
data analysis	9
new virus	9
plasma wastage	9
african american	9
mice infected	9
high volume	9
also demonstrated	9
infectious particles	9
linked immunosorbent	9
rbc exchange	9
surface antigen	9
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analytical sensitivity	9
one week	9
zika response	9
von willebrand	9
le virus	9
cells using	9
pizv dose	9
autoimmune hemolytic	9
volume processed	9
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total blood	9
horizontal transmission	9
van den	9
specific antibodies	9
cerus corporation	9
copy number	8
domain iii	8
transmit zika	8
borne flavivirus	8
cmnc protocol	8
simulated transfusion	8
brain microvascular	8
maternal blood	8
mm tris	8
rare donors	8
scale bar	8
concomitant infections	8
multiple comparisons	8
detect zikv	8
severe dengue	8
ortho vision	8
manufacturing methods	8
data sources	8
platelet usage	8
investigate whether	8
ns gene	8
time consuming	8
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analysed using	8
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oneg rbcs	8
genome sequences	8
irradiated rbcs	8
human placenta	8
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immune cell	8
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upload time	8
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procedure cd	8
among pregnant	8
bl mice	8
currently available	8
cell antibodies	8
based assay	8
immunohistochemical staining	8
iron supplementation	8
standard curve	8
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million people	8
flow cytometer	8
serologic properties	8
technologist time	8
lipid metabolism	8
immune globulin	8
readily available	8
disease virus	8
many different	8
buffer solution	8
outside africa	8
zika aptamer	8
vero cell	8
rbc samples	8
pbs buffer	8
emergency units	8
viral protein	8
constant control	8
phylogenetic trees	8
thrombotic thrombocytopenic	8
automated solid	8
nucleotide sequence	8
oneg patients	8
disseminated infection	8
severe reaction	8
give blood	8
triglyceride levels	8
detected using	8
whole viral	8
pe group	8
semen parameters	8
seminiferous tubule	8
also showed	8
infection induces	8
igm positive	8
prbc units	8
neutrophil infiltration	8
escherichia coli	8
three cases	8
confidence interval	8
significant decrease	8
united kingdom	8
viral strains	8
primary infection	8
primary hits	8
sbc programming	8
two weeks	8
spectrum anti	8
represent mean	8
infected individual	8
recombinant type	8
infection rates	8
transmission rates	8
time periods	8
light chain	8
using algan	8
several years	8
first step	8
pak lx	8
gel card	8
neutralizing human	8
plaque assays	8
confirmed cases	8
south pacific	8
calculated using	8
four patients	8
rhd alleles	8
fibrinogen levels	8
labeled ns	8
luminex bead	8
approved drugs	8
cytopathic effect	8
human antibodies	8
study shows	8
travel history	8
reported cases	8
immediate spin	8
group ab	8
implementation period	8
also associated	8
process improvement	8
assay buffer	8
septic patients	8
molecular epidemiology	8
barr virus	8
appointment booking	8
pcr reactions	8
rh phenotype	8
hla matched	8
lineage zika	8
linked zika	8
mosquito vector	8
per animal	8
clinical assays	8
pro domain	8
platelet refractoriness	8
flavivirus infections	8
cytometric method	8
information regarding	8
acute zika	8
plt units	8
health professionals	8
tm cells	8
secondary structure	8
affinity maturation	8
product utilization	8
cobe spectra	8
alloimmunization rates	8
world war	8
deficient mice	8
virus structural	8
blood utilization	8
based assays	8
services background	8
transfusion related	8
urine samples	8
ediii proteins	8
effective treatment	8
immunodetection assay	8
virus exposure	8
testicular atrophy	8
preliminary report	8
patients treated	8
brain organoids	8
hgb hct	8
developing countries	8
two distinct	8
personal protection	8
data collected	8
old male	8
drug repurposing	8
phylogenetic tree	8
decidual nk	8
associated microcephaly	8
matched platelets	8
protein concentration	8
encephalitis viruses	8
different stages	8
emergent situations	8
thrombin generation	8
secondary antibody	8
abo blood	8
dna samples	8
liquid chromatography	8
medical director	8
may play	8
transcription factor	8
fold serial	8
digital pathogen	8
bpn bottles	8
viral titers	8
ex vivo	8
pcr amplicon	8
human cortical	8
close proximity	8
suspected cases	8
neurologic complications	8
partial plasma	8
rapid risk	8
seeking behaviors	8
times higher	8
behavior change	8
six compounds	8
confer protection	8
molecular detection	8
national reference	8
culture results	8
orp values	8
specific memory	8
blood mononuclear	8
linked ns	8
antibody levels	8
preterm labor	8
using routine	8
lethal infection	8
study evaluated	8
considered significant	8
alcoholic steatohepatitis	8
group antigen	8
mathematical modeling	8
blood flow	8
clinical use	8
time donors	8
amplicon sequencing	8
following transfusion	8
wastage rates	8
different blood	8
viral persistence	8
human zikv	8
misfolded unfolded	8
ferritin testing	8
host interactions	8
gene expression	8
evidence review	8
three groups	8
rh blood	8
dot represents	8
based methods	8
storage duration	8
mutation frequency	8
climate change	8
emergently issued	8
infected humans	8
cells derived	8
strain mr	8
rabies virus	8
mab binding	8
rna synthesis	8
eggs collected	8
potential sexual	8
ongoing zika	8
mortality rate	8
placental tissues	8
new data	8
surveillance systems	8
medical history	8
specific hits	8
platelet clearance	8
assay performance	8
cell adherence	8
normal saline	8
forward primer	8
transfusion hemoglobin	8
typing results	8
factors associated	8
mosquito repellent	8
skin cells	8
group antigens	8
platelet yield	8
viral titres	8
cell response	8
prevent sexual	8
automated gel	8
significant effect	8
nonhuman primates	8
affected countries	8
zikv exposure	8
hematological parameters	8
protective effect	8
matched units	8
congenital defects	8
transmitted infections	8
healthy donors	8
mp content	8
tpe procedures	8
results show	8
molecular tweezer	8
zikv serology	7
mini kit	7
term storage	7
igm antibodies	7
waste management	7
adult ag	7
george chen	7
four different	7
antiviral therapy	7
adjoint system	7
respiratory infections	7
dara interference	7
prioritization process	7
process steps	7
human fetal	7
social media	7
continuous variables	7
old man	7
testing algorithm	7
total bilirubin	7
olfactory nerve	7
laboratory results	7
assessed using	7
nanopore sequencing	7
mirasol prt	7
operations demand	7
acid test	7
global distribution	7
le diagnostic	7
washed twice	7
true positive	7
weakly positive	7
valley fever	7
transfusion hgb	7
assays perform	7
family flaviviridae	7
analysis using	7
antibodies targeting	7
rheumatoid arthritis	7
healthy volunteers	7
dna extracted	7
acute pancreatitis	7
human cells	7
among patients	7
neutralising antibodies	7
patients infected	7
retrospective cohort	7
cellular responses	7
broadly neutralizing	7
sequence analysis	7
oxygen affinity	7
using gamma	7
ig genes	7
acid testing	7
zikv vaccine	7
model parameters	7
molecular biology	7
water bath	7
flaccid paralysis	7
also inhibits	7
death rate	7
platelet aggregation	7
ic value	7
receptor binding	7
infection using	7
neonatal sepsis	7
donation frequency	7
cell antigens	7
denv serotypes	7
complete blood	7
growth factor	7
recent study	7
serological tests	7
rbc genotyping	7
hospital based	7
log pfu	7
patients showed	7
rift valley	7
iron stores	7
bacterial infection	7
vector population	7
disease patients	7
nonhuman primate	7
rare blood	7
reagent management	7
clinical care	7
sequencing data	7
slightly lower	7
study also	7
brain tissue	7
antibodies directed	7
fort collins	7
mosquito eggs	7
become infected	7
secure texting	7
transmitted infection	7
ct group	7
year following	7
adamts activity	7
zika protease	7
procleix zikv	7
random blood	7
zikv multiplication	7
amino acids	7
interim guidelines	7
data points	7
blood fridge	7
individual donation	7
seizure activity	7
done using	7
coagulation parameters	7
acute flaccid	7
null phenotype	7
two years	7
reduction technology	7
confocal microscopy	7
zikv infects	7
rad laboratories	7
months post	7
renal failure	7
hospital system	7
broad spectrum	7
pneumatic tube	7
serological testing	7
also evaluated	7
scientific community	7
pcr amplification	7
vps scores	7
international travel	7
per milliliter	7
one rbc	7
transmission routes	7
adamts deficiency	7
i tool	7
transfusion support	7
mk cells	7
following zikv	7
first identified	7
age groups	7
measles virus	7
old woman	7
george schlauder	7
knockout mice	7
swab samples	7
experimental models	7
operator touchpoints	7
virus spreads	7
cell activation	7
antibodies prevent	7
animal reservoirs	7
gregg williams	7
high inhibitor	7
binding site	7
icu patients	7
comparative analysis	7
level i	7
syndromic surveillance	7
medicine service	7
en charge	7
placental blood	7
jane bryant	7
dpi inclusively	7
calcusyn computer	7
zikv diagnostic	7
cd yield	7
ost complex	7
army institute	7
highly efficacious	7
greater impact	7
emerging pathogens	7
like syndrome	7
community hospitals	7
five years	7
maximum surgical	7
mers cov	7
mark paradowski	7
obtained using	7
health sciences	7
like receptor	7
ifn signaling	7
fatty acid	7
drug discovery	7
potent human	7
relatively low	7
medical students	7
molecular genotyping	7
repose sur	7
cmap amplitude	7
iatrogenic blood	7
clinical specimens	7
health security	7
inflammatory cytokines	7
clr concentrations	7
related failed	7
infected patient	7
mosquito population	7
reticulum stress	7
negative antibody	7
regulatory requirements	7
potential association	7
virus envelope	7
infectious pathogens	7
molecular tweezers	7
analysis showed	7
specific cd	7
published literature	7
culex quinquefasciatus	7
broad range	7
procedures performed	7
based potentiometric	7
commodity waste	7
htlv ii	7
york blood	7
care professionals	7
virus isolation	7
new technology	7
additional studies	7
several months	7
different clr	7
retest options	7
partial protection	7
rh confirmation	7
den driessche	7
vaccine efficacy	7
ai applications	7
laboratory medicine	7
antibodies elicited	7
future state	7
unit transfusion	7
persistently infected	7
protective immunity	7
positive rbcs	7
clerical errors	7
seven days	7
congenital hcmv	7
nonstructural proteins	7
cfu ml	7
lung injury	7
current evidence	7
untreated control	7
big data	7
dexamethasone withdrawal	7
mg ml	7
enhanced automation	7
hemoglobin level	7
analysis resource	7
developed countries	7
salivary glands	7
preterm delivery	7
cell membrane	7
virus shedding	7
infection damages	7
reduce zikv	7
fetal microcephaly	7
inhibiting zikv	7
virus pathogen	7
function research	7
sequence data	7
esd implementation	7
mutagenic activity	7
healthcare system	7
prise en	7
isotype control	7
globally asymptotically	7
wireless sensor	7
hemorrhagic shock	7
drain current	7
clinical disease	7
prevent transfusion	7
en france	7
zikv molecular	7
primary antibody	7
i cv	7
routinely used	7
become pregnant	7
hospital customers	7
serial passage	7
quantitative pcr	7
automatic appointment	7
control samples	7
abnormal risk	7
existing immunity	7
cell concentrates	7
epidemic areas	7
high level	7
babesia microti	7
expert systems	7
genetic diversity	7
increased walk	7
bank testing	7
received ivig	7
onset disease	7
tetravalent dengue	7
electronic ordering	7
transfusion protocols	7
risks associated	7
prediction algorithm	7
hearing loss	7
two samples	7
global public	7
test result	7
rhce variants	7
oxygen delivery	7
prospective cohort	7
computer program	7
autochthonous transmission	7
ag mouse	7
surveillance system	7
baseline data	7
reduction neutralization	7
reactive antibodies	7
transfused per	7
mean number	7
infection control	7
tubing segments	7
fluorescence signal	7
tested mabs	7
microvascular endothelial	7
rh haplotypes	7
genome copy	7
wbc ul	7
panel cells	7
denv ediii	7
zikv immunodetection	7
abbott diagnostics	7
emergency committee	7
emerging diseases	7
dtt treated	7
donor deferrals	7
background information	7
findings suggested	7
immunosorbent assay	7
transfusion guidelines	7
least two	7
short term	7
higher rates	7
epidemic potential	7
virus causes	7
well plate	7
samples showed	7
staphylococcus aureus	7
zika patient	7
lateral ridge	7
mouse brain	7
des patients	7
virus targets	7
clinical significance	7
exchange transfusion	7
microglial cells	7
zimmer biomet	7
inactivated virus	7
job aid	7
human induced	7
converting enzyme	7
detection system	7
false positives	7
leydig cells	7
zikv genome	7
university medical	7
oxidative stress	7
clinical laboratory	7
predictive value	7
viruses zika	7
cell transfusion	7
study day	7
dependent rna	7
will need	7
priority behaviors	7
possible zika	7
passive transfer	7
sgs assembly	7
viral envelope	7
infected pregnant	7
small numbers	7
inflammatory cells	7
population immunity	7
may present	7
health background	7
cancer center	7
controlled trials	7
sporadic cases	7
index donations	7
base station	7
health preparedness	7
identified natural	7
blood units	7
abo discrepancy	7
platelet collection	7
continued pressures	7
urgent need	7
dans le	7
higher levels	7
may represent	7
neonatal intensive	7
remote blood	7
infected mosquitoes	7
des signes	7
human disease	7
blood bags	7
walk away	7
also important	7
potent neutralization	7
journal articles	7
dara treatment	7
different viral	7
antibody testing	7
exclude concomitant	7
diagnostic samples	7
basic health	7
group received	7
induced damage	7
based zikv	7
year post	7
treatment time	6
viral spread	6
laboratory diagnosis	6
bacterial meningitis	6
also called	6
vivo protection	6
virus stocks	6
rhd allele	6
also found	6
confidence intervals	6
infusion pump	6
human rights	6
fetal infection	6
products ordered	6
i trauma	6
health information	6
secondary tma	6
specific antiviral	6
products collected	6
warm autoimmune	6
observed increase	6
organ transplants	6
emergency room	6
dna testing	6
high quality	6
phosphatidylserine exposure	6
constant regions	6
zoonotic diseases	6
graphpad software	6
also includes	6
mouse anti	6
natural phenol	6
new emerging	6
cardiovascular surgery	6
dried plasma	6
automated result	6
fetal bovine	6
ordering practices	6
pcr system	6
giving rise	6
targeted antibodies	6
congenital cmv	6
first recognized	6
bleeding patients	6
increasing number	6
zikv persistence	6
epidemiological data	6
fresh levels	6
timely manner	6
final volume	6
clinical syndromes	6
high mortality	6
platelet loss	6
assess whether	6
infect dis	6
infected group	6
virus isolates	6
supplemental testing	6
gene sequence	6
maternal infection	6
virus neutralization	6
digital disease	6
potential risks	6
bone needle	6
conformational changes	6
will also	6
four serotypes	6
platelet donations	6
retrospective chart	6
laboratory capacity	6
data available	6
transfusion transmission	6
platelet cd	6
del zika	6
animal care	6
aptamer paper	6
pregnant females	6
comfort level	6
washed three	6
hepatocellular carcinoma	6
cell suspension	6
cell therapy	6
mammalian cell	6
prevalence antigen	6
platelet concentration	6
six months	6
golgi apparatus	6
third party	6
multiple studies	6
eea countries	6
kit ii	6
highly effective	6
whether clr	6
may cause	6
health impact	6
post hoc	6
sequence similarity	6
new insights	6
dna viruses	6
critical care	6
first week	6
basic training	6
factor xiii	6
citrate toxicity	6
antibody formation	6
described previously	6
transmission events	6
three years	6
virus infectivity	6
bank information	6
pizv doses	6
mice without	6
ed bakker	6
parasites ml	6
allogeneic donors	6
detection using	6
transfusion strategies	6
uv fluorescence	6
development zika	6
lateral ventricles	6
lactate dehydrogenase	6
dengue serotypes	6
significantly reduces	6
lower risk	6
zikv full	6
whole virus	6
spotted fever	6
cell separators	6
buccal swabs	6
routine clinical	6
zoster virus	6
rhd sequencing	6
central venous	6
mtor inhibitors	6
time frame	6
table shows	6
leading cause	6
high dose	6
antigen positive	6
plasma pas	6
platforms capable	6
virus evolution	6
growth factors	6
antiviral therapies	6
bis tage	6
infection causes	6
four dengue	6
hpa antibodies	6
uc tissue	6
small volume	6
qualtex laboratories	6
bank staff	6
low cost	6
health systems	6
wbc counts	6
epidemic spread	6
avis relatif	6
virus via	6
transfusion volume	6
low frequency	6
viral inactivation	6
prevent unnecessary	6
search queries	6
rational design	6
inclusion criteria	6
induced pluripotent	6
individuals infected	6
counter measures	6
causes birth	6
molecular sieving	6
months later	6
clinical study	6
developmental delays	6
clinical course	6
edible plants	6
south china	6
evidence based	6
decidual immune	6
zika viral	6
diagnostic kits	6
emerging infections	6
transfusion therapy	6
sensitivity analysis	6
sigma aldrich	6
performed within	6
virus persistence	6
insect repellents	6
rhce gene	6
electronic system	6
specific neutralizing	6
silver paint	6
usaid implementing	6
wbc concentration	6
free state	6
patient rbcs	6
contact information	6
pilot period	6
donors may	6
total protein	6
frozen storage	6
institutional review	6
plt ct	6
avec une	6
ko mice	6
automated attendant	6
transfusion sample	6
information systems	6
test battery	6
abbott laboratories	6
among humans	6
supply program	6
mediated endocytosis	6
current zika	6
statistical analyses	6
ngs methods	6
human pathogens	6
cv access	6
structural biology	6
central blood	6
global response	6
dna extraction	6
zikv pathogenesis	6
target cells	6
donor units	6
condom use	6
will provide	6
enrichment sequencing	6
level trauma	6
local blood	6
vector laboratories	6
hoec cells	6
infected human	6
serine protease	6
experiments involving	6
transcription pcr	6
eye drops	6
type iii	6
will help	6
related complications	6
international health	6
care hospital	6
funding agencies	6
relatively small	6
diagnostics background	6
european centre	6
approved drug	6
genetic testing	6
pic kel	6
cardiac troponin	6
new drug	6
promising candidate	6
human volunteers	6
health regulations	6
reading frame	6
recurrent episodes	6
intrinsically disordered	6
highly potent	6
joint pain	6
new method	6
transmission may	6
cells via	6
hour post	6
treated rrbc	6
donor recruitment	6
igm igg	6
arachidonic acid	6
hospitalization isolation	6
closed conformation	6
cell counter	6
units tested	6
rhd dar	6
novel viruses	6
infected male	6
varying degrees	6
fungal infections	6
blood types	6
assay provided	6
limited countries	6
complete viral	6
negative rbc	6
dengue infectivity	6
primary antibodies	6
human decidual	6
also noted	6
immunocompetent mice	6
performance characteristics	6
jackson immunoresearch	6
inhibit viral	6
molecular analysis	6
rbc order	6
mild disease	6
von bis	6
commons attribution	6
recent ebola	6
autologous plasma	6
human cell	6
state university	6
ct plts	6
laboratories background	6
also determined	6
days following	6
neonatal microcephaly	6
treated pcs	6
antimalarial drug	6
total plasma	6
haemorrhagic fever	6
cell lymphoma	6
littermate neonates	6
malaria parasite	6
shown previously	6
ebola vaccine	6
strains isolated	6
new technologies	6
high viral	6
neutralization assay	6
platelet fraction	6
tfn hct	6
biotin interference	6
plasma transfusion	6
production pools	6
small molecule	6
transfused rbcs	6
using flow	6
past years	6
human populations	6
manual gel	6
african strain	6
collected using	6
rbcs transfused	6
without affecting	6
iu dose	6
infection also	6
glial cells	6
cell monolayers	6
clinical application	6
human challenge	6
matched controls	6
du chikungunya	6
dengue transmission	6
specific human	6
also identified	6
thioglycolic acid	6
inactivated vaccines	6
diagnostic capacity	6
mise en	6
virus outbreaks	6
add ml	6
acute zikv	6
transmission zika	6
thermo scientific	6
internal medicine	6
total human	6
molecular evolution	6
wb units	6
buccal swab	6
weeks later	6
vitro studies	6
first line	6
treatment group	6
storage conditions	6
maternal viremia	6
mortality rates	6
target antigen	6
taken together	6
variable regions	6
higher incidence	6
infected population	6
like particles	6
ml penicillin	6
fda guidance	6
fetal harm	6
statistically different	6
cell type	6
congenital microcephaly	6
six sigma	6
chronic hepatitis	6
mass gatherings	6
information provided	6
supplementary material	6
african lineage	6
infected ag	6
population health	6
viral membrane	6
aedes africanus	6
donors tested	6
subsequently transfused	6
ml whole	6
term water	6
available data	6
cell counting	6
confirmatory testing	6
error catastrophe	6
significantly associated	6
mononuclear cell	6
storage time	6
us studies	6
mutagenic drugs	6
neurite extension	6
suspected congenital	6
three independent	6
index donation	6
study investigated	6
cell phenotype	6
health seeking	6
early pregnancy	6
culture bottles	6
macaque model	6
cytometric analysis	6
using minitab	6
activated protein	6
incidental findings	6
chikungunya fever	6
three months	6
molecular determinants	6
igg antibodies	6
transfusion yield	6
data streams	6
initial reactive	6
troponin i	6
preliminary data	6
scid mice	6
mouth disease	6
yet another	6
sample pairs	6
total volume	6
host disease	6
every minutes	6
may allow	6
cd antigen	6
behavior prioritization	6
treatment groups	6
gel cards	6
surgical research	6
automated testing	6
neglected diseases	6
genetic analysis	6
heel stick	6
technical staff	6
convalescent patient	6
plasma reacted	6
also assessed	6
transfusion laboratory	6
virus inoculation	6
log reduction	6
reproductive age	6
phenotypically matched	6
three zikv	6
infected mouse	6
viral life	6