bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
respiratory tract	184
hereditary angioedema	103
epithelial cells	98
inh concentrate	93
chronic rhinosinusitis	91
respiratory syncytial	91
syncytial virus	89
inh deficiency	87
factor xii	77
viral infection	73
acute respiratory	71
asthmatic patients	64
immune response	61
older adults	55
tract infections	55
allergy clin	51
clin immunol	51
viral infections	51
type i	44
airway epithelial	43
severe covid	40
tract infection	40
common cold	40
angioedema attacks	40
immunol doi	39
cord uid	39
doc id	39
inhibitor deficiency	39
rhinovirus infection	38
gene expression	38
hereditary angioneurotic	38
rsv infection	37
nh gene	36
elderly patients	33
innate immune	32
type ii	32
virus infection	32
first year	32
type iii	32
viral respiratory	32
online repository	31
hae attacks	31
severe cases	31
esterase inhibitor	30
ace inhibitor	30
upper respiratory	30
hae type	29
control subjects	29
immune responses	29
coronavirus disease	28
inhibitor gene	28
angioneurotic edema	28
atopic asthma	28
replacement therapy	27
nasal polyps	26
united states	26
allergic rhinitis	25
nonallergic angioedema	25
asthma exacerbations	25
lung function	25
respiratory viruses	25
converting enzyme	25
respiratory viral	24
tract viruses	24
term prophylaxis	24
adverse effects	24
chronic obstructive	23
attenuated androgens	23
experimental rhinovirus	23
maternal asthma	23
emergency department	23
inh function	22
airway inflammation	22
respiratory distress	22
ace inhibitors	22
vascular permeability	22
laryngeal edema	22
air pollution	21
disease severity	21
tract illness	21
hereditary angio	21
side effects	20
critically ill	20
pulmonary disease	20
primary hypogammaglobulinemia	20
abdominal pain	20
general population	20
inherited angioedema	20
increased risk	20
allergic disease	20
specific ige	20
innate immunity	19
bacterial biofilm	19
nitric oxide	19
human nasal	19
elderly asthmatic	19
childhood asthma	19
severe acute	19
contact system	19
pao fio	19
clinical phenotypes	19
cord blood	19
table i	18
tranexamic acid	18
obstructive pulmonary	18
influenza virus	18
odds ratio	18
factor xiia	18
age years	18
cytokine storm	18
risk factors	18
table ii	18
distress syndrome	18
lower respiratory	18
allergic diseases	17
acute attacks	17
serum levels	17
tmprss expression	17
airway obstruction	17
inh concentration	17
bronchial epithelial	17
health care	17
human subjects	17
respiratory syndrome	17
immune system	16
patients infected	16
asthma control	16
acute abdominal	16
bradykinin receptor	16
home therapy	16
ace expression	16
asthma symptoms	16
acquired angioedema	16
bronchoalveolar lavage	16
upper airway	16
infected patients	15
airflow obstruction	15
patients receiving	15
hungarian hae	15
plasma kallikrein	15
age group	15
clinical characteristics	15
ige levels	15
peripheral blood	15
biofilm formation	15
mucociliary clearance	15
early childhood	15
older asthmatic	15
controlled trial	15
allergic asthma	15
cohort study	15
submucosal glands	14
influenza vaccine	14
intensive care	14
complement activation	14
patients treated	14
nonsevere cases	14
adjusted odds	14
acute attack	14
epithelial cell	14
nasopharyngeal microbiota	14
tract viral	14
may also	14
rag mutations	14
nasal lavage	14
inflammatory response	14
related angioedema	14
edematous attacks	14
statistically significant	14
respiratory infections	14
i hereditary	14
local immune	13
previously described	13
angioneurotic oedema	13
novel coronavirus	13
angioedema caused	13
logistic regression	13
ill patients	13
clinical trial	13
airway hyperreactivity	13
induced aris	13
severe patients	13
inhaled corticosteroids	13
like receptor	13
amino acid	13
healthy controls	13
environmental factors	13
amino acids	13
lavage fluid	13
inh concentrations	13
antifibrinolytic agents	13
control group	13
inflammatory responses	12
molecular weight	12
plasma concentrations	12
case series	12
phase ii	12
pediatric patients	12
human plasma	12
nasal epithelial	12
recurrent angioedema	12
factor xia	12
microbiota profiles	12
human rhinovirus	12
bacterial biofilms	12
oxygen requirement	12
high levels	12
lung disease	12
cell receptor	12
sex hormones	12
danazol treatment	12
significantly higher	12
chronic sinusitis	12
many patients	12
dominant profile	12
host response	12
hospitalized patients	12
cell numbers	12
public health	12
relative abundance	12
nasal swabs	12
attack therapy	12
angioedema associated	12
clinical trials	12
sinus surgery	12
influenza infection	12
rhinovirus colds	12
reactive protein	12
see table	12
allergic airway	11
xii activation	11
several studies	11
viral load	11
might also	11
systematic review	11
endothelial cells	11
aminopeptidase activity	11
clinical course	11
nasal secretions	11
inh protein	11
nonatopic asthma	11
host defense	11
one study	11
randomized controlled	11
family members	11
abdominal attacks	11
nucleic acid	11
allergen sensitization	11
heart failure	11
wide range	11
omenn syndrome	11
mouse model	11
mechanical ventilation	11
oral contraception	11
case reports	11
plasminogen activator	11
ap activity	11
staphylococcus aureus	10
asthma exacerbation	10
receptor antagonists	10
pg ml	10
among infants	10
sample size	10
determine whether	10
among patients	10
genetic variant	10
rag protein	10
clinical symptoms	10
hae center	10
induced ari	10
aminocaproic acid	10
recent studies	10
reported asthma	10
significant differences	10
increased levels	10
present study	10
severe asthma	10
early life	10
abdominal attack	10
dendritic cells	10
airway disease	10
familial predisposition	10
human airway	10
inhibitor concentrate	10
clinical manifestations	10
skin prick	10
informed consent	10
angiotensin system	10
rsv ari	10
better understanding	10
epithelial barrier	10
syndrome coronavirus	10
test results	10
recombinant human	10
virus categories	10
viral cause	10
within hours	10
clinical presentation	10
complement components	10
asthmatic participants	10
contact activation	10
relative odds	10
induced lrtis	10
kinin inactivation	10
identify patients	10
nasal polyposis	10
refractory crs	10
adaptive immune	9
rrna gene	9
day intubation	9
postmenopausal women	9
nasal mucosa	9
virus safety	9
functional activity	9
classical pathway	9
allergen exposure	9
different clinical	9
baseline il	9
animal models	9
time pcr	9
treg cells	9
recombination activity	9
ex vivo	9
human metapneumovirus	9
corticosteroid use	9
bacterial infection	9
department visits	9
respiratory pathogens	9
hae attack	9
hageman factor	9
inflammatory mediators	9
rhinoviral infections	9
mg ml	9
total ige	9
care unit	9
prospective cohort	9
young children	9
plasma bradykinin	9
icu admission	9
patients hospitalized	9
prick test	9
increased expression	9
clinical signs	9
increased susceptibility	9
angiotensin ii	9
previous studies	9
ifng mrna	9
high il	9
microbial interactions	9
blood samples	9
infection severity	9
inflammatory cells	9
bitter taste	9
year follow	9
viral replication	9
like receptors	9
weight kininogen	9
respiratory virus	9
objective measures	9
normal range	9
ill cases	9
healthy control	9
factor xi	9
asthmatic subjects	9
dependent inherited	9
mononuclear cells	9
mendelian randomization	9
hormone replacement	9
respiratory disease	8
barrier function	8
older patients	8
inhaled corticosteroid	8
respiratory failure	8
immune mediators	8
oral corticosteroids	8
findings suggest	8
even though	8
vasoactive peptide	8
cell surface	8
propensity score	8
severe bronchiolitis	8
endoscopic sinus	8
per month	8
cytokine production	8
infant respiratory	8
lung injury	8
increased relative	8
world health	8
without asthma	8
cell entry	8
adult patients	8
genetic correlation	8
blood monocytes	8
natural history	8
normal values	8
recurrent respiratory	8
respiratory infection	8
lupus erythematosus	8
intubation mortality	8
skin test	8
mast cells	8
rhinovirus species	8
final concentration	8
healthy subjects	8
taste receptor	8
neutralizing antibodies	8
multisystem inflammatory	8
respiratory illness	8
ccl mrna	8
less frequently	8
cell subsets	8
clinical outcome	8
high prevalence	8
respiratory symptoms	8
unpublished data	8
physical performance	8
older persons	8
clinical features	8
free peritoneal	8
cardiovascular disease	8
peritoneal fluid	8
younger asthmatic	8
angioedema patients	8
phase i	8
reduced expression	8
target protease	8
deficiency workshop	8
another study	8
whose mothers	8
related changes	8
birth weight	8
induced sputum	8
nasal swab	8
flow cytometry	8
clinical studies	8
risk factor	8
vasoactive peptides	8
recent study	8
immune cells	8
atopic dermatitis	8
immune function	8
airway hyperresponsiveness	8
asthma care	8
combined immunodeficiency	8
important role	7
well established	7
high molecular	7
rsv infections	7
rat brain	7
severe respiratory	7
cell population	7
kallikrein inhibitor	7
gene sequencing	7
systemic lupus	7
median age	7
medical care	7
antimicrobial proteins	7
female patients	7
multiple comparisons	7
younger patients	7
serum concentrations	7
protease inhibitor	7
laboratory findings	7
health study	7
infant dyads	7
rhinoviral pcr	7
may increase	7
bradykinin generation	7
virus infections	7
intestinal wall	7
health organization	7
airflow limitation	7
antiviral agents	7
ldh level	7
sinus mucosa	7
severe disease	7
laboratory diagnosis	7
described previously	7
mutation database	7
congestive heart	7
lavage samples	7
pcr results	7
study found	7
alternaria species	7
cytokine responses	7
clinical phenotype	7
many different	7
binding protein	7
receptor antagonist	7
adenoviral infection	7
factor viii	7
high risk	7
atopic predisposition	7
acute asthma	7
receptor gene	7
gene use	7
healthy participants	7
sinonasal epithelial	7
proinflammatory cytokines	7
high ldh	7
asthma development	7
studies suggest	7
danazol therapy	7
upper airways	7
preoperative prophylaxis	7
airway epithelium	7
carbohydrate groups	7
higher levels	7
inflammatory syndrome	7
observational study	7
prophylactic treatment	7
junction proteins	7
regression model	7
national institute	7
elderly patient	7
mutant protein	7
serum ige	7
transcription factor	7
angioedema attack	7
fungal biofilm	7
antiviral response	7
two patients	7
onset asthma	7
serum amyloid	7
serine protease	7
commonly used	7
infants whose	7
treatment options	7
higher prevalence	7
maxillary sinusitis	7
aging process	7
factors associated	7
correct diagnosis	6
serum complement	6
reactive site	6
probable asthma	6
untreated patients	6
familial atopic	6
may lead	6
widely used	6
adjusted analyses	6
blood institute	6
analyzed using	6
smooth muscle	6
primary care	6
severe combined	6
patients diagnosed	6
also shown	6
wheezing illnesses	6
recombinase activity	6
significantly reduced	6
decreased levels	6
higher risk	6
tris hcl	6
ii hereditary	6
monoclonal antibody	6
nucleotide sequence	6
autoimmune diseases	6
might cause	6
free periods	6
gc qr	6
new type	6
severe attacks	6
severe abdominal	6
virus validation	6
primary immunodeficiency	6
pathway activation	6
apoptotic cells	6
immunol volume	6
angioedema may	6
induced asthma	6
normal subjects	6
genetic variants	6
total protein	6
epigenetic changes	6
exhaled nitric	6
activated factor	6
randomized clinical	6
women taking	6
cell types	6
cell differentiation	6
linkage analysis	6
concerted action	6
lung diseases	6
care workers	6
elderly persons	6
pmol min	6
polygenic risk	6
similar results	6
sputum samples	6
intervention group	6
aventis behring	6
pattern recognition	6
dyax corp	6
reported maternal	6
cigarette smoke	6
university hospital	6
lesser extent	6
aminopeptidase activities	6
naturally occurring	6
tris buffer	6
increased amounts	6
intrinsic pathway	6
ff complement	6
day oxygen	6
patients showed	6
rag transcription	6
associated angioedema	6
ifng gene	6
airway responsiveness	6
inactivation pathways	6
tract illnesses	6
bacterial infections	6
validation studies	6
type inflammation	6
inh mutants	6
edema formation	6
soluble ps	6
residual rag	6
patients also	6
receptor editing	6
applied biosystems	6
radial immunodiffusion	6
small sample	6
psoriasis patients	6
inh functional	6
decreased expression	6
bronchiolitis severity	6
maximum survival	6
well tolerated	6
older age	6
airway microbiota	6
cystic ovaries	6
respiratory allergy	6
dextran sulfate	6
provide evidence	6
nh mutations	6
immune cell	6
bacterial culture	6
inhibitor treatment	6
diagnostic criteria	6
low il	6
respiratory illnesses	6
may result	6
immune dysregulation	6
autoimmune hemolytic	6
inh autoantibodies	6
cardiovascular health	6
national health	6
serpin function	6
highly sensitive	6
high mortality	6
lopinavir ritonavir	6
categorical variables	6
reactive center	6
induced angioedema	6
room temperature	6
national heart	6
study included	6
asthma compared	6
potential adverse	6
hemolytic anemia	6
cell activation	6
inflammatory cytokines	6
included patients	6
incompletely understood	6
gastrointestinal tract	6
common variable	6
protease inhibitors	6
table iii	6
month intervals	6
binding lectin	6
arg bradykinin	6
mechanisms underlying	6
definite asthma	6
viral clearance	6
significant difference	6
natural killer	6
healthy adults	6
also increased	6
antimicrobial peptides	6
angioedema due	6
surfactant protein	6
dna methylation	6
allergic mice	6
nasopharyngeal relative	6
activation markers	6
variable immunodeficiency	6
therapy program	6
molecular techniques	6
follicle wall	6
immunoglobulin replacement	6
target proteases	6
kinin system	6
infectious diseases	6
promising approaches	6
common diseases	6
research nurse	5
human bocavirus	5
mg protein	5
including il	5
young adults	5
major mediator	5
stimulated gene	5
food allergy	5
increased vascular	5
primary defect	5
effective dose	5
severely ill	5
sputum sample	5
neutral endopeptidase	5
human microbiome	5
severe angioedema	5
drug administration	5
antiviral activity	5
cell repertoire	5
human bronchial	5
autosomal dominant	5
aging might	5
derived products	5
sensitized mice	5
trait meta	5
rag activity	5
allergic response	5
sinus secretions	5
angioedema without	5
memory cd	5
evidence suggests	5
attacks may	5
years old	5
weight gain	5
immune activation	5
table vi	5
inflammatory bowel	5
shared genetic	5
without nasal	5
clinical data	5
trait analysis	5
covid patients	5
statistical significance	5
tissue kallikrein	5
functional deficiency	5
life questionnaire	5
type immune	5
acid test	5
clinical outcomes	5
acquired pneumonia	5
significantly lower	5
cell response	5
mortality rates	5
respiratory rate	5
high plasma	5
unclear whether	5
clinical implications	5
angioedema hereditary	5
st louis	5
coding region	5
invasive mechanical	5
among older	5
asthma model	5
ciliary beat	5
protein levels	5
disease expression	5
sputum specimens	5
chronic inflammatory	5
safety concerns	5
gene mutations	5
typical symptoms	5
current understanding	5
medical history	5
higher incidence	5
cd cd	5
whitney test	5
plasma samples	5
antiviral drugs	5
cell counts	5
peak flow	5
first years	5
tcz treatment	5
acid sequence	5
mutually exclusive	5
atopic disease	5
cytokine levels	5
future research	5
vascular leakage	5
late tcz	5
fold increased	5
erythema marginatum	5
hand hygiene	5
glandular exocytosis	5
current asthma	5
virus bronchiolitis	5
positive results	5
candidate genes	5
small number	5
activating gene	5
abdominal ultrasound	5
skin tests	5
previous study	5
lower airway	5
enzyme inhibitors	5
severe coronavirus	5
lymphoproliferative disorders	5
signaling pathways	5
glycosylation sites	5
hyperinflammatory milieu	5
patients may	5
angioedema symptoms	5
cell expansion	5
patients undergoing	5
colonic eosinophilia	5
elderly population	5
known hae	5
angiotensin i	5
leading cause	5
oral contraceptives	5
bowel disease	5
maternal atopic	5
inh plasma	5
serum immunoglobulin	5
taste receptors	5
disorders associated	5
biologic therapies	5
multiplex pcr	5
patients without	5
blood mononuclear	5
chronic asthma	5
vital signs	5
many studies	5
deficiency angioedema	5
related disorders	5
host immune	5
degrading aminopeptidase	5
edematous swelling	5
complement function	5
authors note	5
deficient mice	5
stat activation	5
angiotensin converting	5
close relationship	5
human beings	5
estrogen therapy	5
rag genes	5
enzyme activity	5
protective effect	5
study population	5
serine proteases	5
exact test	5
acquired deficiency	5
acute bronchiolitis	5
several small	5
every months	5
statistical analyses	5
mortality rate	5
ifng response	5
chart review	5
asthma quality	5
showed increased	5
ii receptor	5
highly conserved	5
inh levels	5
later immune	5
chronic respiratory	5
african american	5
type cytokines	5
health measures	5
adult asthmatic	5
well known	5
primary defects	5
common colds	5
turbinate epithelial	5
may vary	5
per year	5
complement cascade	5
mechanical trauma	5
tight junction	5
asymptomatic subjects	5
neutrophil activation	5
taken together	5
circulating biomarkers	5
increased airway	5
investigated whether	5
coronavirus pneumonia	5
negative control	5
severe exacerbation	5
autoimmune disease	5
one patient	5
dna sequence	5
estrogen replacement	5
gene rearrangements	5
broad spectrum	5
european countries	5
icu patients	5
respiratory health	5
ordinal scale	5
kinin formation	5
also known	5
specific pathogens	5
partly explain	5
molecular mass	5
distilled water	5
bronchial asthma	5
sensitive aminopeptidase	5
hae caused	5
wide cross	5
patients compared	5
high level	5
transgenic rabbits	5
severe influenza	5
asthma research	5
inh gene	5
murine model	5
release syndrome	5
functional analysis	5
rare diseases	5
institutional review	5
family history	5
month period	5
sequence analysis	5
biofilm detection	5
cytological grading	5
rag mutation	5
normal sinus	5
complex traits	5
inh may	5
beat frequency	5
treated patients	5
maxillary sinus	5
adult population	5
attack frequency	5
clinical syndrome	5
mouse models	5
reproductive age	5
elderly might	5
nasal cytology	5
pulmonary function	4
questions regarding	4
cell development	4
patient characteristics	4
severe symptoms	4
sinus infections	4
predicted value	4
recognition receptor	4
viral pathogens	4
human sinonasal	4
lung pathology	4
severe illness	4
acute episodes	4
therapeutic approaches	4
laboratory data	4
nasal symptoms	4
functional assays	4
asthma susceptibility	4
aging study	4
complement component	4
swab samples	4
asthma prevalence	4
plasma proteins	4
national institutes	4
inflammatory conditions	4
tissue inflammation	4
mean age	4
eosinophilic inflammation	4
recent evidence	4
requiring hospitalization	4
use may	4
ii interferon	4
using real	4
rheumatoid arthritis	4
tissue damage	4
neutrophilic inflammation	4
mg daily	4
signal transduction	4
strongly associated	4
clinical presentations	4
patients whose	4
virus inactivation	4
new mutation	4
turku university	4
pseudomonas aeruginosa	4
studies linking	4
ultrasound examination	4
whose angioedema	4
sars coronavirus	4
pathogenic viruses	4
major role	4
surgical emergency	4
reference database	4
necrosis factor	4
normative aging	4
symptomatic relief	4
successfully treated	4
dose inhaler	4
multicenter prospective	4
adult covid	4
low prevalence	4
chronic lung	4
type plasminogen	4
versus rsv	4
abdominal symptoms	4
atopic status	4
hospital admissions	4
abdominal hae	4
helicobacter pylori	4
online data	4
whereas others	4
similar mutations	4
family member	4
might predispose	4
least different	4
clinically proven	4
regression analysis	4
birth cohort	4
receiving ace	4
reversible airflow	4
promoter sequence	4
ovarian follicular	4
nontemplate controls	4
stimulating hormone	4
allergen challenge	4
bradykinin receptors	4
allergic inflammation	4
damaged cells	4
baylor college	4
ace inhibition	4
human influenza	4
table iv	4
interferon signaling	4
advancing age	4
nanoparticle vaccine	4
mutation detection	4
patients requiring	4
natural product	4
clinical cytological	4
per day	4
known whether	4
paranasal sinuses	4
differential diagnosis	4
lymphocyte count	4
messenger rna	4
lung epithelial	4
microbial community	4
transcription levels	4
inflammatory markers	4
abdominal edema	4
pulmonary vascular	4
asthma mortality	4
myocardial infarction	4
many elderly	4
san diego	4
acute viral	4
infants hospitalized	4
undergoing surgical	4
linkage disequilibrium	4
dual inhibitor	4
clinical development	4
acute lung	4
lymph node	4
might partly	4
sequence data	4
among children	4
reduce mortality	4
entry depends	4
human respiratory	4
within minutes	4
respiratory diseases	4
cell responses	4
interferon production	4
receptor signaling	4
inh activity	4
newly diagnosed	4
received research	4
long cdr	4
adverse effect	4
viral upper	4
surgical intervention	4
young patients	4
twin pairs	4
pulmonary changes	4
phospholipid microparticles	4
fvc ratio	4
danazol prophylaxis	4
sialic acid	4
like symptoms	4
wide search	4
may occur	4
gastroesophageal reflux	4
rag proteins	4
review board	4
mutations resulting	4
critical care	4
situ hybridization	4
severe complications	4
although several	4
pathophysiologic mechanisms	4
nasal polyp	4
scanning laser	4
ap secretion	4
recently described	4
continuous variables	4
cellular immune	4
atopic subjects	4
induced bronchiolitis	4
chronic maxillary	4
phage display	4
latent adenoviral	4
obstructive lung	4
airway wall	4
inflammatory disease	4
life expectancy	4
chemokine production	4
tobacco smoke	4
cell type	4
bronchial hyperresponsiveness	4
mrna copies	4
bone mass	4
likely results	4
enteroviral infections	4
antibiotic treatment	4
bradykinin concentrations	4
inh inhibits	4
classic pathway	4
factor ix	4
immune mediator	4
function testing	4
requiring imv	4
follicular fluid	4
confocal scanning	4
approximately mg	4
genomic dna	4
parainfluenza type	4
rsv rna	4
also reported	4
asthmatic children	4
sinus mucosal	4
prospective study	4
pathogenic bacteria	4
vitro studies	4
antimicrobial effects	4
proven protease	4
median time	4
proteins involved	4
increased serum	4
physical function	4
gene polymorphisms	4
inhibitory effects	4
physical activity	4
cxcl levels	4
disease burden	4
quantitative trait	4
cells comprise	4
kininase i	4
thrombin generation	4
early stage	4
inflammatory processes	4
infectious agents	4
genetic factors	4
increase susceptibility	4
associated diseases	4
cytokine release	4
controlled study	4
biological activity	4
may decrease	4
whole genome	4
sinus tissue	4
statistical analysis	4
blood count	4
i study	4
receptor expression	4
remains elusive	4
aged years	4
functional decline	4
without evidence	4
severe rsv	4
tlr signaling	4
determined based	4
laser microscopy	4
even higher	4
social distancing	4
dataset gse	4
positively correlated	4
bacterial burden	4
potential confounders	4
race ethnicity	4
clinically significant	4
tongji hospital	4
symptomatic patients	4
multicenter study	4
binding site	4
mg kg	4
nasal epithelium	4
high concentrations	4
might contribute	4
adverse events	4
negatively charged	4
bone marrow	4
inh molecule	4
parainfluenza viruses	4
adverse outcome	4
recent years	4
every weeks	4
wide association	4
dynein arms	4
early intervention	4
protein kinase	4
ifit ifi	4
fungal infection	4
environmental interactions	4
female patient	4
lod score	4
similar rag	4
genome screens	4
causes type	4
statistical computing	4
nucleic acids	4
international hae	4
pichia pastoris	4
heart disease	4
patients presenting	4
gel electrophoresis	4
complement deficiency	4
genetic defect	4
much higher	4
mucosal samples	4
serpin domain	4
emergency departments	4
suppl table	4
demographic characteristics	4
viii concentrate	4
cascade systems	4
growth factor	4
nasal washes	4
nitrogen dioxide	4
also found	4
longer duration	4
androgen treatment	4
cases compared	4
mrna expression	4
persistent asthma	4
acute illness	4
environmental exposures	4
thrombocytopenic purpura	4
cognitive impairment	4
rhinovirus infections	4
normal human	4
pulmonary edema	4
infancy respiratory	4
significant correlation	4
virus reduction	4
molecular basis	4
neuraminidase inhibitors	4
protein expression	4
care visit	4
plaque psoriasis	4
inflammatory diseases	4
climate change	4
molecular biology	4
asthmatic patient	4
hay fever	4
viral shedding	4
normal levels	4
microbiota profile	4
dz twins	4
plasma levels	4
small studies	4
universal influenza	4
global initiative	4
one may	4
antigenic concentration	4
first days	4
min mg	4
data protection	4
serum total	4
induced ifng	4
allergic sensitization	4
nonallergic individuals	4
associated inherited	4
plasmin formation	4
bronchodilator response	4
response might	4
predict asthma	4
considered significant	4
middle age	4
interquartile range	4
nh mutation	4
research support	4
epidemiologic studies	4
year period	4
old female	4
new therapeutic	4
infection rates	4
will help	4
asthma risk	4
inflammatory pathways	4
tyrosine kinase	4
quality control	4
inh serpin	4
fold increase	4
oc use	4
common cause	4
live attenuated	4
asthma therapy	4
severity score	4
cell function	4
hae patient	4
taken every	4
sinus epithelium	4
modifier genes	4
data supplement	4
oxygen saturation	4
confidence intervals	4
nasopharyngeal airway	4
hospital admission	4
endothelial cell	4
mediated angioedema	4
postviral asthma	4
intubation death	4
bradykinin formation	4
human complement	4
recalcitrant nasal	4
pcr products	4
cell production	4
day care	4
might explain	4
dose corticosteroid	4
point mutations	4
terminal domain	4
based study	4
threatening laryngeal	4
health status	4
house dust	4
activated receptor	4
cell lymphopenia	4
dna vaccine	4
fev fvc	4
bone turnover	4
results suggest	4
function relationships	4
min ml	4
study design	4
attack generation	4
acute hae	4
common symptom	4
angioedema type	4
wide variety	4
low numbers	4
community study	4
developing angioedema	4
ultrasound pattern	4
rna polymerase	4
matched healthy	4
inh mice	4
immunoreactive material	4
asthma medications	4
dendritic cell	4
transgenic animals	4
nasal airway	4
infant viral	4
rhinovirus illnesses	4
acute wheezing	4
may help	4
model included	4
nobel prize	4
staphylococcal superantigens	4
dust mites	4
tlr expression	4
gene anomalies	4
patients admitted	4
association study	4
antiviral drug	4
guide pa	3
cytokine milieu	3
future treatment	3
study using	3
medical information	3
serum carboxypeptidase	3
studies using	3
depressive disorder	3
maximum concentration	3
immunomodulatory drugs	3
i went	3
cold symptoms	3
clinical observations	3
either hrv	3
glandular secretion	3
patients taking	3
became negative	3
correlation analysis	3
recurrent bacterial	3
activating factor	3
patients reported	3
acute phase	3
ct scan	3
occurred less	3
increased bacterial	3
cysteinyl leukotriene	3
peak expiratory	3
ari group	3
truncated rag	3
fungal allergens	3
goblet cell	3
frozen plasma	3
steroid use	3
zlb behring	3
performance battery	3
plasma concentrate	3
plasma cascade	3
expiratory flow	3
chemokine rantes	3
might well	3
cause exacerbation	3
significantly negatively	3
also reduce	3
mean difference	3
patient education	3
genetic defects	3
likelihood ratio	3
fixed airflow	3
quantitative pcr	3
currently known	3
per sample	3
many questions	3
working group	3
largely unknown	3
eosinophils hpf	3
negative bacterial	3
also thank	3
human alveolar	3
tables i	3
extrinsic pathway	3
least parent	3
kunitz domain	3
certain degree	3
commercially available	3
several decades	3
may regulate	3
human genome	3
different types	3
psoriasis receiving	3
study performed	3
airway infection	3
cell populations	3
sole hrv	3
cystic fibrosis	3
allergic disorders	3
copy number	3
allergy skin	3
polymerase chain	3
genetic correlations	3
negative bacteria	3
virus species	3
prophylactic use	3
fish oil	3
hae association	3
response translates	3
haemolytic anaemia	3
enrolled infants	3
asymptomatic infection	3
cell proliferation	3
severe anxiety	3
predispose patients	3
aae type	3
airway samples	3
underlying defects	3
cleaved hk	3
rhinosinusitis biofilms	3
receptor blockers	3
heat shock	3
performed significantly	3
therapeutic interventions	3
inhibitor complexes	3
advanced age	3
notably lactoferrin	3
patients date	3
insurance type	3
induced wheezing	3
might provide	3
bactericidal permeability	3
first described	3
relatively low	3
positive skin	3
retrospective observational	3
nasal endoscopy	3
microbial balance	3
effective means	3
million people	3
first time	3
increased wheezing	3
african americans	3
routine methods	3
chicken soup	3
novo mutations	3
many challenges	3
cxcl protein	3
medical center	3
unrelated patients	3
infectious disease	3
upper limit	3
cell rna	3
nasopharyngeal swab	3
airways reactivity	3
driven genes	3
recurrent wheezing	3
control test	3
containing oc	3
acute edematous	3
recent research	3
oxidative stress	3
specific virus	3
also detected	3
observational studies	3
often requires	3
develop angioedema	3
requiring oxygen	3
subjects infected	3
among african	3
intolerant asthma	3
individual variation	3
adenovirus might	3
several proteases	3
neutrophil elastase	3
negative correlation	3
enkephalin degrading	3
preventing acute	3
nonhistaminergic angioedema	3
truncating rag	3
antiviral immunity	3
ige antibodies	3
submucosal mixed	3
leukocyte elastase	3
human volunteers	3
known causes	3
persistent respiratory	3
gene sequence	3
room air	3
population sample	3
authors suggest	3
early tcz	3
future investigation	3
health policies	3
types i	3
one hundred	3
dimensional model	3
gestational age	3
causal role	3
candidate mediator	3
may contribute	3
longitudinal study	3
typing assay	3
superoxide dismutase	3
reference values	3
electronic medical	3
studies reported	3
ang ii	3
severe outcomes	3
environmental impacts	3
negative regulator	3
killer cells	3
prophylactic therapy	3
normal concentrations	3
occur without	3
ng ml	3
i interferon	3
elevated serum	3
missing data	3
routine laboratory	3
cumulative dose	3
crs remains	3
different mutations	3
interstitial lung	3
elevated plasma	3
complex interplay	3
large deletions	3
weighted unifrac	3
immunocompetent subjects	3
human il	3
vascular endothelial	3
chromosomal region	3
enhances virus	3
strong genetic	3
functional limitations	3
randomized trial	3
cell recruitment	3
increases tmprss	3
respiratory questionnaire	3
abdominal manifestations	3
i interferons	3
developed severe	3
asthma management	3
human lung	3
abstract background	3
experimental infection	3
yield insights	3
us hae	3
participants demonstrate	3
chronic hepatitis	3
will require	3
subsequent childhood	3
test reactivity	3
year old	3
elderly asthma	3
association studies	3
dependent angioedema	3
patients first	3
infant hrv	3
based algorithms	3
natural products	3
asthmatic response	3
aureus biofilm	3
normal airway	3
synergistic effect	3
rhinovirus replication	3
angioedema occurred	3
tcz showed	3
different disease	3
passive immunization	3
ige production	3
women whose	3
term danazol	3
patients clinical	3
reduce kinin	3
provide insights	3
inhibitory capacity	3
years ago	3
extensively studied	3
kinin generation	3
bal fluid	3
relative rate	3
also important	3
factor xiif	3
way anova	3
active site	3
chemokine levels	3
delayed viral	3
patients received	3
differential regulation	3
increased incidence	3
total number	3
younger adults	3
otitis media	3
predictive accuracy	3
gov grants	3
tight junctions	3
minimum effective	3
last accessed	3
infant infection	3
infection effect	3
extremity function	3
complement pathway	3
analysis revealed	3
vasopeptidase inhibition	3
creatine kinase	3
respiratory support	3
significantly associated	3
office visits	3
also provide	3
expression compared	3
microbial dna	3
negative staphylococcus	3
virus detection	3
developed recurrent	3
school children	3
skin inflammation	3
exon deletions	3
viral bronchiolitis	3
may play	3
app activity	3
acute symptoms	3
inhibitory activity	3
using pcr	3
microbiome project	3
induced airway	3
study inclusion	3
patient developed	3
translates respiratory	3
chronic enteroviral	3
infection might	3
specific treatment	3
pandemic decrease	3
residual recombinase	3
unstimulated pbmcs	3
phase iii	3
higher likelihood	3
elastic recoil	3
attack rate	3
mild symptoms	3
normal complement	3
laryngeal attacks	3
sheep model	3
response patterns	3
affected family	3
early onset	3
resistant aminopeptidase	3
diagnosing asthma	3
angioedema plasma	3
first component	3
oxygen tension	3
also observed	3
mg dl	3
live dead	3
mobility disability	3
higher frequency	3
asthma among	3
yet another	3
wheezing children	3
regular medical	3
leukocyte antigen	3
examined whether	3
significant increase	3
alkylated androgens	3
experimentally induced	3
rhinosinusitis expression	3
deficient patients	3
may explain	3
persistent infection	3
expression levels	3
biologically active	3
research suggests	3
rhinovirus rna	3
type littermates	3
blood pressure	3
bacterial lysate	3
nasal spray	3
allergic responses	3
active complement	3
muscle weakness	3
mitigating disease	3
within days	3
mononuclear cell	3
ltc synthase	3
also performed	3
distinct nasopharyngeal	3
beneficial effect	3
asthma might	3
distinct genetic	3
low cd	3
recombinant interferon	3
inh antigenic	3
lactate dehydrogenase	3
diagnostic tests	3
pcr analysis	3
irregular menstruation	3
produce ifn	3
occur less	3
genetic analysis	3
nonsteroidal anti	3
cell markers	3
also showed	3
even without	3
neutralizing antibody	3
cd cells	3
virus fusion	3
profuse diarrhea	3
replicative senescence	3
factor binding	3
register will	3
mismatch analysis	3
goblet cells	3
acute infection	3
infection clinical	3
complement measurements	3
must also	3
another group	3
receptor blockade	3
serous cells	3
previously reported	3
antifungal treatment	3
reply date	3
often associated	3
fungal dna	3
preschool children	3
older women	3
terminal truncated	3
control specimens	3
per patient	3
six patients	3
comorbid illnesses	3
multivariable analysis	3
prevent functional	3
sequence variants	3
gene transcription	3
total lymphocyte	3
nervous system	3
will environmental	3
arterial oxygen	3
lower airways	3
positive patients	3
great interest	3
data suggest	3
whereas additional	3
leukotriene production	3
allergic angioedema	3
dr expression	3
pulmonary inflammation	3
citrated plasma	3
attack per	3
available data	3
hae treatment	3
distinct immunologic	3
manufacturing procedure	3
virus entry	3
lower prevalence	3
nursing home	3
fibrinolytic system	3
aged animals	3
laboratory criteria	3
acute lower	3
related adverse	3
future studies	3
missing factor	3
may become	3
pathways might	3
null mutations	3
demonstrate lower	3
pediatric hae	3
clinical picture	3
critical role	3
mbl deficiency	3
inh antigen	3
global health	3
drosophila species	3
plasma pool	3
structural changes	3
leukocyte subsets	3
host cell	3
us children	3
specific cells	3
large epidemiologic	3
high sensitivity	3
severe chronic	3
patient association	3
illness onset	3
dose danazol	3
decreased ifn	3
bone mineral	3
risk children	3
human immunodeficiency	3
terminal part	3
associated serine	3
less severe	3
dental surgery	3
inh preparations	3
diagnosed patients	3
stat phosphorylation	3
hae register	3
exact mid	3
restoring host	3
exaggerated response	3
february th	3
lung inflammation	3
escherichia coli	3
stranded rna	3
files pa	3
antiviral strategies	3
rag deficiency	3
clinical research	3
pathology database	3
viral properties	3
icu group	3
viral susceptibility	3
low plasma	3
adaptive immunity	3
cross laps	3
increasing evidence	3
case report	3
neutrophilic asthma	3
diagnostic tool	3
lrti subgroup	3
human monocytes	3
will also	3
chain reaction	3
using molecular	3
airway diseases	3
induce leakage	3
several patients	3
cells may	3
reported cases	3
performance measures	3
receiving biologic	3
ari severity	3
rhinoviral infection	3
cov infection	3
clinical practice	3
episodes occurred	3
receptor ace	3
respiratory function	3
induced interferon	3
healthy children	3
proportional odds	3
approximately kd	3
asked whether	3
test system	3
blood products	3
nasopharyngeal microbiome	3
virus shedding	3
beckman coulter	3
lymphoid cells	3
current evidence	3
drug discovery	3
idiopathic nonhistaminergic	3
currently unknown	3
serum igg	3
cells per	3
high affinity	3
plunc protein	3
adverse clinical	3
low functional	3
response toward	3
bacterial pathogens	3
cell tolerance	3
highly specific	3
activation via	3
blood cell	3
flow lability	3
plasma protein	3
exogenous estrogen	3
chemokine gene	3
individual patient	3
hepatocellular adenoma	3
medical costs	3
autoimmune haemolytic	3
just like	3
measured using	3
survival analysis	3
ighj gene	3
cardiac injury	3
rank sum	3
complement values	3
terminal truncation	3
human blood	3
elder age	3
liver function	3
nasal lavages	3
decrease allergic	3
lower limits	3
common prophylaxis	3
severe outcome	3
pcr assay	3
gland cells	3
symptom onset	3
alveolar macrophages	3
mucociliary function	3
highly effective	3
recurrent abdominal	3
bone metabolism	3
gene product	3
closely resemble	3
hypovolemic shock	3
maternal race	3
hae patients	3
idiopathic thrombocytopenic	3
clinical response	3
trophic unit	3
table viii	3
knockout mice	3
cell metaplasia	3
helper type	3
laboratory parameters	3
adequate immunoglobulin	3
intercellular adhesion	3
main clinical	3
clinical relevance	3
viral cultivation	3
results indicate	3
severe clinical	3
unadjusted analyses	3
new york	3
chromogenic assay	3
induced protein	3
standardized incidence	3
high asthma	3
bound aminopeptidases	3
young asthmatic	3
kinin metabolism	3
immune reaction	3
unproductive rearrangements	3
horizontal pleiotropy	3
wilcoxon rank	3
autoimmune acquired	3
cell signaling	3
disease onset	3
mild asthma	3
estrogen concentrations	3
temperomandibular pain	3
especially important	3
inhibitor alone	3
ribosomal rna	3
early stages	3
highly relevant	3
viral culture	3
inhibitor activity	3
mechanisms may	3
primary ciliary	3
care use	3
receptor system	3
electron microscopy	3
pulmonary rehabilitation	3
oral contraceptive	3
might reflect	3
acquired deficiencies	3
results demonstrate	3
adults identify	3
prove useful	3
first step	3
innate inflammatory	3
lymphocyte counts	3
microscopy evidence	3
three patients	3
linked agammaglobulinemia	3
bradykinin concentration	3
novel mutations	3
less effective	3
european commission	3
mutation analysis	3
data collection	3
throat swabs	3
inhibitor deficiencies	3
significantly worse	3
maximum lifespan	3
direct sequencing	3
international study	3
body mass	3
allergic patients	3
crs undergoing	3
mucous cells	3
chemokine receptor	3
cold air	3
nonhomologous end	3
adhesion molecule	3
taking oral	3
safety parameters	3
angioedema activation	3
patients might	3
preliminary report	3
dominant microbiota	3
also seen	3
nk cells	3
sag motif	3
life time	3
inversely correlated	3
safety profile	3
infected human	3
induced lung	3
mg per	3
cross lap	3
economic burden	3
cytokine secretion	3
will provide	3
effective treatment	3
therapeutic targets	3
asthma education	3
acute airway	3
periovulatory period	3
mechanisms leading	3
humoral immune	3
ischemic heart	3
face masks	3
recombinant protein	3
olfactory dysfunction	3
cardiac involvement	3
grade ccg	3
host inflammatory	3
gene causes	3
immature neutrophils	3
surface markers	3
rna viruses	3
primary outcome	3
recently found	3
clinical manifestation	3
induced activation	3
anaerobic bacteria	3
dry cough	3
like particles	3
based chromogenic	3
myeloid cells	3
old children	3
adverse reactions	3
intravenous immunoglobulin	3
grants guide	3
whereas levels	3
study also	3
fatty acids	3
surgical outcomes	3
saline challenge	3
proinflammatory cytokine	3
rna sequencing	3
cutting edge	3
molecular typing	3
genetic basis	3
increased sensitivity	3
first attack	3
increased severity	3
respiratory system	3
proteinase inhibitor	3
nanoparticle vaccines	3
dental procedures	3
potential risk	3
latter study	3
previous reports	3
american academy	3
outcome variable	3
angioedema treated	3
foster city	3
respiratory morbidity	3
children hospitalized	3
assay range	3
clinical decision	3
mixed glands	3
medication use	3
affected individuals	3
subsequently processed	3
viruses might	3
persistent activation	3
specific genes	3
recognition receptors	3
cell composition	3
bm mononuclear	3
angioedema generation	3
adjusted relative	3
mesenchymal trophic	3
markedly elevated	3
negative likelihood	3
prospective studies	3
without urticaria	3
cell expression	3
internal medicine	3
tumor necrosis	3
marco cicardi	3
health systems	3
performed using	3
deficiency workshops	3
rehabilitation program	3
spearman correlation	3
eosinophil cytolysis	3
older men	3
data indicate	3
edema episodes	3
ciliary dyskinesia	3
genes associated	3
propidium iodide	3
basal condition	3
possible role	3
cultured epithelial	3
human leukocyte	3
nonenveloped viruses	3
viral proteins	3
mg dx	3
total serum	3
incidence ratios	3
antibiotic treatments	3
allergy sensitization	3
multinomial logistic	3
following sections	3
term hae	3
interferon response	3
peak production	3
mutations result	3
current study	3
functionally active	3
constitutively expressed	3
physiological changes	3
triage tool	3
nasal cavity	3
well suited	3
dust mite	3
increasing protein	3
consistent finding	3
acting bronchodilator	3
delayed menarche	3
normal individuals	3
rat model	3
asthma subtypes	3
staphylococcus species	3
life predict	3
allergic individuals	3
therapeutic options	3
term treatment	3
signal transducer	3
york city	3
fusion protein	3
sulfur dioxide	3
increase kinin	3
cells might	3
expired air	3
rhinosinusitis bacterial	3
low number	3
starting oc	3
shock protein	3
mrna production	3
elderly adults	3
terminal phe	3
unique sequences	3
severe case	3
greater risk	3
rag mouse	3
among subjects	3
lower limit	3
written informed	3
estrogencontaining medications	3
short physical	3
soluble cd	3
growth factors	3
virus vaccine	3
lt receptor	3
irreversible airflow	3
chemokine expression	3
current investigation	3
health consequences	3
maternal smoking	3
experimental models	3
chest tightness	3
major depressive	3
significantly different	3
human ovarian	3
unscheduled health	3
protease specificity	3
subjects asthma	3
innate pattern	3
bronchial reactivity	3
host responses	3
disease control	3
mucosal surface	3
endotracheal intubation	3
th cells	3
jk genes	3
also analyzed	3
higher doses	3
might account	3
care utilization	3
lung dendritic	3
laboratory analyses	3
molecular characterization	3
studies showing	3
positive allergy	3
fresh frozen	3
clinical information	3
uncontrolled activation	3
sample collection	3
oedema acquired	3
bromide nasal	3
data capture	3
different viral	3
particulate matter	3
also includes	3
antagonist eritoran	3
ipratropium bromide	3
rhinosinusitis patients	3
secretory leukocyte	3
twice weekly	3
ethnically diverse	3
weeks later	3
type cytokine	3
classic hae	3
mucosal inflammation	3
decision making	3
mycobacterium avium	3
controlled clinical	3
dna vaccines	3
indoor air	3
may persist	3
nasal challenge	3
louis site	3
seasonal influenza	3
terminal truncating	3
angioedema treatment	3
transgenic rhc	3
asthma attacks	3
test result	3
risk score	3
system proteases	3
intestinal epithelial	3
patient populations	3
incidence rates	3
different stages	3
hae results	3
stop codon	3
nonadherent cells	3
distancing due	3
surface antigen	3
pulmonary dysfunction	3
seasonal allergic	3
treatments might	3
might lead	3
markedly higher	3
confidence interval	3
corticosteroid therapy	2
producing cells	2
current knowledge	2
novel rsv	2
later development	2
plasma pools	2
normal saline	2
controller medication	2
also well	2
correlation coefficients	2
alanine aminopeptidase	2
plus cigarette	2
increased numbers	2
inflammation process	2
another important	2
allergic reaction	2
ang i	2
severe gi	2
multiplex identifier	2
collaborative study	2
jkik lb	2
subsequent wheezing	2
asthma severity	2
another consistent	2
detectable virus	2
karen binkley	2
negative regulation	2
vaginal delivery	2
bradykinin type	2
clinical study	2
org summarizes	2
diffusing capacity	2
rsv induction	2
inhaling heated	2
patient group	2
mechanistic role	2
eosin staining	2
human herpesvirus	2
mu mg	2
contact information	2
nasal eosinophilia	2
broadly neutralizing	2
igkj genes	2
dmbt interacts	2
comparing nonsevere	2
synthetic kunitz	2
diagnosed asthma	2
spike glycoprotein	2
abs responses	2
model human	2
month prior	2
infant bronchiolitis	2
versus older	2
sensing molecule	2
viral rna	2
preoperative prophylactic	2
antibody formation	2
cyproterone acetate	2
th week	2
potential therapeutic	2
table xvii	2
mycophenolate mofetil	2
lung damage	2
precipitating factors	2
femoral neck	2
pilot study	2
sdbj ca	2
class ii	2
functional concentration	2
among women	2
natural colds	2
meso scale	2
leukocyte proteinase	2
cytokines associated	2
membrane oxygenation	2
organ dysfunction	2
similar procedures	2
airway cytokines	2
bradykinin degradation	2
factors might	2
trial conducted	2
induces expression	2
less clear	2
maternal atopy	2
iv crq	2
separate analyses	2
healthy donors	2
group compared	2
ige receptor	2
multicentre study	2
serious consequences	2
descriptive study	2
type natriuretic	2
intranasal amphotericin	2
strong biomarker	2
lead active	2
certain viruses	2
several adverse	2
total population	2
viral nsp	2
available measures	2
transmembrane protease	2
comparative study	2
edematous attack	2
disease prevalence	2
cell secretion	2
oseltamivir use	2
start site	2
production process	2
provides evidence	2
contact phase	2
damp indoor	2
rsv bronchiolitis	2
causative factor	2
polyp tissues	2
autoimmune cytopenias	2
human pathogens	2
rare cases	2
high fraction	2
hierarchical clustering	2
guanine nucleotide	2
care attendance	2
onset scid	2
binding pocket	2
disease pathophysiologic	2
nasopharyngeal haemophilus	2
mg methacholine	2
worsening asthma	2
pancreatic region	2
effective virus	2
gene mutation	2
experimental model	2
acute myocardial	2
concentrate twice	2
active kallikrein	2
pasteurization procedure	2
threatening attacks	2
well chamber	2
nonallergic subjects	2
immune deficiency	2
lower extremities	2
ct abnormalities	2
serum angiotensin	2
viral binding	2
local hyperthermia	2
socs haploinsufficiency	2
subcutaneous edema	2
frequently resistant	2
late onset	2
medical staff	2
prevent acute	2
rich inflammation	2
estrogen regulation	2
lifetime history	2
least patient	2
type asthma	2
models included	2
unsupervised hierarchical	2
new drug	2
side effect	2
racial differences	2
shs exposure	2
preovulatory follicle	2
biomarker association	2
environmental drivers	2
infections caused	2
many possible	2
despite severe	2
hae typically	2
derived neurovirulent	2
prognostic value	2
dna rearrangements	2
may yield	2
underlying mechanism	2
serine nasal	2
identification document	2
large amount	2
coronavirus hcov	2
preferential use	2
underlying defect	2
young syndrome	2
dna extraction	2
control levels	2
smaller animals	2
maximum mg	2
medical resources	2
antimicrobial peptide	2
diseases traits	2
lymphocyte blood	2
receptor agonists	2
medical record	2
patients provided	2
per well	2
ifit ifit	2
causal relationship	2
achieve satisfactory	2
commonly caused	2
low albumin	2
pivotal role	2
patients inhaling	2
produced mainly	2
induced ifn	2
severe immunopathology	2
edema may	2
patients underwent	2
acute infections	2
stranded dna	2
icu treatment	2
decreased mortality	2
transplant recipients	2
dependent complement	2
specific cd	2
weight development	2
current treatment	2
classified women	2