This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.
trigram | frequency |
---|---|
severe acute respiratory | 155 |
the supplemental material | 155 |
acute respiratory syndrome | 149 |
in the supplemental | 144 |
the presence of | 142 |
respiratory syndrome coronavirus | 140 |
s in the | 108 |
as well as | 95 |
h n influenza | 87 |
middle east respiratory | 81 |
east respiratory syndrome | 80 |
influenza a virus | 77 |
nsp and nsp | 77 |
the number of | 71 |
the absence of | 71 |
in the lungs | 66 |
analysis of the | 59 |
the lungs of | 56 |
in the absence | 55 |
h n virus | 53 |
in the presence | 51 |
the expression of | 50 |
in this study | 50 |
the role of | 50 |
as previously described | 48 |
according to the | 48 |
table s in | 47 |
influenza virus infection | 47 |
of h n | 46 |
of rna viruses | 46 |
in addition to | 45 |
the use of | 45 |
the development of | 44 |
compared to the | 44 |
of severe acute | 44 |
in order to | 43 |
see table s | 43 |
the cells were | 42 |
of the viral | 41 |
due to the | 41 |
of the virus | 41 |
at room temperature | 40 |
for min at | 40 |
we found that | 40 |
based on the | 39 |
and h n | 39 |
data not shown | 38 |
it has been | 37 |
n influenza virus | 37 |
a and b | 37 |
in the lung | 37 |
was added to | 36 |
members of the | 36 |
was used to | 36 |
to determine whether | 36 |
has been shown | 35 |
the formation of | 35 |
the united states | 35 |
the ability of | 34 |
the case of | 34 |
mice infected with | 34 |
the h n | 34 |
been shown to | 33 |
to determine the | 33 |
of rnase l | 33 |
a number of | 33 |
of influenza a | 33 |
the probability of | 33 |
is required for | 33 |
as described previously | 32 |
one of the | 32 |
in the case | 32 |
in the united | 32 |
respiratory syncytial virus | 32 |
for h at | 31 |
h n and | 31 |
the activation of | 31 |
in response to | 30 |
an moi of | 30 |
consistent with the | 30 |
cells infected with | 29 |
human immunodeficiency virus | 29 |
of a novel | 29 |
the urokinase pathway | 29 |
were infected with | 28 |
at an moi | 28 |
were used to | 28 |
the lack of | 27 |
the context of | 27 |
c bl j | 27 |
activation of the | 27 |
of the host | 27 |
the university of | 27 |
a total of | 27 |
shown in fig | 26 |
the s protein | 26 |
similar to those | 26 |
associated with the | 26 |
those of the | 26 |
cov ma infection | 26 |
present in the | 26 |
a h n | 26 |
were obtained from | 26 |
t cell activation | 26 |
the evolution of | 26 |
in escherichia coli | 26 |
supplemental material for | 25 |
in the context | 25 |
cells were infected | 25 |
genes at hpi | 25 |
the importance of | 25 |
the viral genome | 25 |
the host response | 25 |
the viroporin domain | 25 |
region of the | 25 |
of small rnas | 25 |
data suggest that | 25 |
observed in the | 25 |
in the same | 25 |
suggesting that the | 24 |
porcine epidemic diarrhea | 24 |
in contrast to | 24 |
veroe tmprss cells | 24 |
virus titers in | 24 |
as described above | 24 |
such as the | 24 |
small rna loci | 24 |
c bl mefs | 23 |
added to the | 23 |
the p x | 23 |
t cells were | 23 |
the cell surface | 23 |
of viral rna | 23 |
the majority of | 23 |
at the time | 23 |
p x r | 23 |
of influenza virus | 23 |
the level of | 23 |
was performed using | 23 |
avian influenza a | 23 |
all of the | 23 |
the levels of | 23 |
innate immune response | 23 |
to that of | 23 |
was observed in | 23 |
the immune response | 23 |
has not been | 22 |
fetal bovine serum | 22 |
be found at | 22 |
the binding of | 22 |
human parainfluenza virus | 22 |
may be found | 22 |
of middle east | 22 |
immune response to | 22 |
hepatitis c virus | 22 |
cov nsp and | 22 |
that of the | 22 |
n influenza a | 22 |
indicating that the | 22 |
activation of rnase | 22 |
a novel coronavirus | 22 |
found to be | 22 |
the emergence of | 22 |
to those of | 22 |
found in the | 21 |
n and h | 21 |
acute lung injury | 21 |
this article may | 21 |
the percentage of | 21 |
of rna virus | 21 |
it is possible | 21 |
expression of the | 21 |
thermo fisher scientific | 21 |
p x receptor | 21 |
article may be | 21 |
a set of | 21 |
material for this | 21 |
for this article | 21 |
changes in the | 21 |
host response to | 21 |
h n viruses | 21 |
the ability to | 21 |
is consistent with | 21 |
were stained with | 21 |
highly pathogenic avian | 21 |
similar to that | 20 |
the complement system | 20 |
the end of | 20 |
cells were washed | 20 |
the time of | 20 |
some of the | 20 |
b and c | 20 |
the effects of | 20 |
of nsp and | 20 |
were determined by | 19 |
the fact that | 19 |
a role in | 19 |
were observed in | 19 |
e and f | 19 |
in cell culture | 19 |
the possibility that | 19 |
for the presence | 19 |
the ph n | 19 |
immunodeficiency virus type | 19 |
results suggest that | 19 |
epidemic diarrhea virus | 19 |
because of the | 19 |
each of the | 19 |
the middle east | 19 |
were cultured in | 19 |
hek t cells | 19 |
see also fig | 19 |
putative small rna | 19 |
in patients with | 19 |
was used as | 19 |
mutations in the | 19 |
is possible that | 19 |
was determined by | 19 |
cells were cultured | 18 |
virus in the | 18 |
is known to | 18 |
cells were incubated | 18 |
at least one | 18 |
the loss of | 18 |
part of the | 18 |
cells in the | 18 |
our understanding of | 18 |
in unexposed subjects | 18 |
known to be | 18 |
the severe acute | 18 |
in which the | 18 |
characterization of a | 18 |
results indicate that | 18 |
c and d | 18 |
suggest that the | 18 |
influenza virus transmission | 18 |
in vero cells | 18 |
pathogenic avian influenza | 18 |
cells treated with | 18 |
was supported by | 18 |
related to the | 18 |
with pandemic potential | 18 |
structure of the | 18 |
a in the | 18 |
of convalescent plasma | 18 |
used as a | 17 |
pattern recognition receptors | 17 |
of the viroporin | 17 |
by plaque assay | 17 |
the production of | 17 |
the onset of | 17 |
in infected cells | 17 |
the rate of | 17 |
large number of | 17 |
and stored at | 17 |
no effect on | 17 |
the gp core | 17 |
of unknown function | 17 |
there is no | 17 |
infectious cdna clone | 17 |
understanding of the | 17 |
responsible for the | 17 |
but not in | 17 |
to identify the | 17 |
from the same | 17 |
of ph n | 17 |
it is important | 17 |
the accumulation of | 17 |
upregulation of cd | 17 |
de genes at | 17 |
the identification of | 17 |
s a in | 17 |
the results of | 17 |
national institute of | 17 |
response to infection | 16 |
in vitro and | 16 |
to investigate the | 16 |
cells were transfected | 16 |
we also observed | 16 |
the innate immune | 16 |
most of the | 16 |
exposed to sars | 16 |
involved in the | 16 |
be used to | 16 |
respiratory distress syndrome | 16 |
s and s | 16 |
dependent rna polymerase | 16 |
of the cells | 16 |
of trsv in | 16 |
resulted in a | 16 |
relative to the | 16 |
balb c mice | 16 |
of the mers | 16 |
of the same | 16 |
were used for | 16 |
closely related to | 16 |
to determine if | 16 |
materials and methods | 16 |
suggests that the | 16 |
in saudi arabia | 16 |
in terms of | 16 |
virus infection in | 16 |
the generation of | 16 |
cell responses to | 16 |
is important to | 16 |
the pathogenesis of | 16 |
for h n | 16 |
multiplicity of infection | 16 |
the lgi network | 16 |
and that the | 16 |
type i interferon | 16 |
the members of | 15 |
was detected in | 15 |
in the future | 15 |
are consistent with | 15 |
mice than in | 15 |
national institutes of | 15 |
open reading frame | 15 |
as shown in | 15 |
of the two | 15 |
avian influenza viruses | 15 |
the effect of | 15 |
were purchased from | 15 |
used in the | 15 |
and infectious diseases | 15 |
green fluorescent protein | 15 |
of the nsp | 15 |
low levels of | 15 |
were exposed to | 15 |
predicted to be | 15 |
the amount of | 15 |
avian influenza virus | 15 |
on the basis | 15 |
response to sars | 15 |
allergy and infectious | 15 |
presence of the | 15 |
the exception of | 15 |
treated control group | 15 |
insight into the | 15 |
c bl mice | 15 |
the glycan cap | 15 |
to virus infection | 15 |
with the exception | 15 |
the basis of | 15 |
were subjected to | 15 |
the s subunit | 15 |
was performed on | 15 |
approved by the | 15 |
of the complement | 15 |
infected with sinv | 15 |
influenza a viruses | 15 |
on influenza virus | 15 |
influenza virus a | 15 |
is associated with | 15 |
in the present | 14 |
at the end | 14 |
were detected in | 14 |
were recovered from | 14 |
obtained from the | 14 |
were able to | 14 |
influenza a h | 14 |
emc and sars | 14 |
of the sars | 14 |
the possibility of | 14 |
rna virus evolution | 14 |
detected in the | 14 |
were provided by | 14 |
airborne transmission of | 14 |
due to a | 14 |
of escherichia coli | 14 |
in table s | 14 |
that it is | 14 |
of allergy and | 14 |
it is not | 14 |
corresponding to the | 14 |
of the urokinase | 14 |
of the h | 14 |
the present study | 14 |
we hypothesized that | 14 |
the public health | 14 |
the research enterprise | 14 |
pandemic h n | 14 |
during virus infection | 14 |
t cell responses | 14 |
of at least | 14 |
characterization of the | 14 |
identified in the | 14 |
of the lung | 14 |
of the human | 14 |
the fatty acid | 14 |
were incubated with | 14 |
at the same | 14 |
in human cells | 14 |
influenza virus h | 14 |
of highly pathogenic | 14 |
institutes of health | 14 |
with influenza virus | 14 |
were found to | 14 |
many of the | 14 |
the plasma membrane | 14 |
of the p | 14 |
is able to | 14 |
infected with the | 14 |
via respiratory droplets | 14 |
not required for | 14 |
virus in ferrets | 13 |
supplemented with fetal | 13 |
the predict pdf | 13 |
to h n | 13 |
of the spike | 13 |
cytokines and chemokines | 13 |
is dependent on | 13 |
against h n | 13 |
droplets or aerosols | 13 |
in dromedary camels | 13 |
at h postinfection | 13 |
scientific catalog no | 13 |
bovine serum albumin | 13 |
respiratory droplets or | 13 |
for min and | 13 |
p values of | 13 |
acute respiratory distress | 13 |
of the protein | 13 |
have been reported | 13 |
x r ko | 13 |
the specificity of | 13 |
are shown in | 13 |
of the genome | 13 |
in c bl | 13 |
are known to | 13 |
the spike protein | 13 |
a combination of | 13 |
exposure to culture | 13 |
were collected at | 13 |
were performed using | 13 |
and stained with | 13 |
using the same | 13 |
been deposited in | 13 |
institute of allergy | 13 |
expression in the | 13 |
a multiplicity of | 13 |
rna was extracted | 13 |
mice immunized with | 13 |
fatty acid and | 13 |
pathogens with pandemic | 13 |
there was no | 13 |
role in the | 13 |
parainfluenza virus type | 13 |
were treated with | 13 |
data indicate that | 13 |
world health organization | 13 |
cells were lysed | 13 |
of t cell | 13 |
well as the | 13 |
a variety of | 13 |
linked glycans on | 13 |
an important role | 13 |
changes in expression | 13 |
open reading frames | 13 |
cultured in the | 13 |
high levels of | 13 |
subunit of the | 13 |
the induction of | 13 |
these data suggest | 13 |
fatty acid synthesis | 13 |
ebola virus glycoprotein | 13 |
streptococcus equi subsp | 13 |
binding to the | 13 |
were generated by | 13 |
were transfected with | 13 |
has been reported | 13 |
gp and gp | 13 |
mouse adenovirus type | 12 |
this is a | 12 |
after the onset | 12 |
for the first | 12 |
of the rna | 12 |
we did not | 12 |
the rdrp tree | 12 |
the regulation of | 12 |
m gene product | 12 |
required for the | 12 |
were resuspended in | 12 |
cells were fixed | 12 |
mbcs reactive to | 12 |
at a multiplicity | 12 |
and characterization of | 12 |
of m pro | 12 |
lookup suppl doi | 12 |
of onward transmission | 12 |
mouse model of | 12 |
have shown that | 12 |
the study of | 12 |
org lookup suppl | 12 |
evolution of the | 12 |
shown to be | 12 |
to the s | 12 |
identification of a | 12 |
found at http | 12 |
segmented filamentous bacteria | 12 |
the removal of | 12 |
of the rdrp | 12 |
group a streptococcus | 12 |
infected c bl | 12 |
from h n | 12 |
the severity of | 12 |
innate and adaptive | 12 |
vesicular stomatitis virus | 12 |
role of the | 12 |
have been deposited | 12 |
the detection of | 12 |
to understand the | 12 |
activity against sars | 12 |
with respect to | 12 |
replication of the | 12 |
of de genes | 12 |
and in vitro | 12 |
the influenza virus | 12 |
on the cell | 12 |
and l of | 12 |
the dimer interface | 12 |
of respiratory disease | 12 |
differential expression of | 12 |
cov m gene | 12 |
experiments were performed | 12 |
a critical role | 12 |
been shown that | 12 |
virus replication in | 12 |
onset of symptoms | 12 |
mediated by the | 12 |
in vivo and | 12 |
pandemic influenza a | 12 |
immune responses to | 12 |
potential pandemic pathogens | 12 |
of the immune | 12 |
are required for | 12 |
the ebola virus | 12 |
correlated with the | 12 |
patients with severe | 12 |
room temperature for | 12 |
the risk of | 12 |
higher than that | 12 |
likely to be | 12 |
adaptive immune responses | 12 |
could also be | 12 |
in the upper | 12 |
depending on the | 12 |
and in vivo | 12 |
as a control | 12 |
was obtained from | 11 |
end of the | 11 |
major histocompatibility complex | 11 |
reactive to the | 11 |
and incubated with | 11 |
acid and pl | 11 |
vitro and in | 11 |
branches of the | 11 |
these results indicate | 11 |
the national institutes | 11 |
is responsible for | 11 |
the likelihood of | 11 |
at and hpi | 11 |
we observed that | 11 |
with fetal bovine | 11 |
rnase l is | 11 |
the small rna | 11 |
was expressed with | 11 |
antiviral activity of | 11 |
in the spike | 11 |
thermo scientific catalog | 11 |
genes that were | 11 |
from the national | 11 |
were performed in | 11 |
the course of | 11 |
infection in a | 11 |
recovered from the | 11 |
to evaluate the | 11 |
for the development | 11 |
and influenza virus | 11 |
isolation of a | 11 |
determine whether the | 11 |
development of a | 11 |
been associated with | 11 |
in h n | 11 |
the same time | 11 |
were harvested and | 11 |
g for min | 11 |
appear to be | 11 |
peripheral blood mononuclear | 11 |
it is also | 11 |
for each sample | 11 |
isolates of s | 11 |
an increase in | 11 |
a and c | 11 |
in l of | 11 |
the efficacy of | 11 |
were added to | 11 |
escape of a | 11 |
incubated for h | 11 |
pkr mrna levels | 11 |
the existence of | 11 |
the first time | 11 |
of fatty acid | 11 |
cells were harvested | 11 |
the treatment of | 11 |
coexpression of nsp | 11 |
cells were then | 11 |
we also thank | 11 |
of the n | 11 |
virus h n | 11 |
the setting of | 11 |
demonstrated that the | 11 |
with pneumonia in | 11 |
the e gene | 11 |
mutations in nsp | 11 |
viral small rnas | 11 |
indicated that the | 11 |
mouse hepatitis virus | 11 |
and incubated at | 11 |
the need for | 11 |
pandemic influenza virus | 11 |
cytokine and chemokine | 11 |
in convalescent subjects | 11 |
care and use | 11 |
we compared the | 11 |
the numbers of | 11 |
and pl synthesis | 11 |
to characterize the | 11 |
crystal structure of | 11 |
was performed by | 11 |
of the viruses | 11 |
to the virus | 11 |
and g ml | 11 |
than in the | 11 |
we observed a | 11 |
of dsrna viruses | 11 |
is essential for | 11 |
remains to be | 11 |
were maintained in | 11 |
novel coronavirus from | 11 |
r ko mice | 11 |
by flow cytometry | 11 |
infected with sars | 11 |
was present in | 11 |
small rnas in | 11 |
contributed to the | 11 |
has shown that | 11 |
with the same | 11 |
tigers and lions | 11 |
is based on | 11 |
the replication of | 11 |
were collected from | 11 |
titers in the | 11 |
was used for | 11 |
at and dpi | 11 |
overlapped with annotated | 11 |
in the setting | 11 |
igg against the | 11 |
views of the | 11 |
potential pandemic pathogen | 11 |
p value of | 10 |
removal of the | 10 |
that may be | 10 |
global rna virome | 10 |
for h and | 10 |
found at https | 10 |
by the presence | 10 |
bl j mice | 10 |
member of the | 10 |
showed that the | 10 |
were compared using | 10 |
of the network | 10 |
analysis of a | 10 |
cells were treated | 10 |
genbank accession no | 10 |
in mammalian cells | 10 |
led to a | 10 |
the construction of | 10 |
one or more | 10 |
activity of the | 10 |
a wide range | 10 |
united states and | 10 |
none of the | 10 |
component of the | 10 |
to confirm the | 10 |
a series of | 10 |
in the middle | 10 |
signs of disease | 10 |
in balb c | 10 |
transmission of influenza | 10 |
to reduce the | 10 |
was detected by | 10 |
found that the | 10 |
influenza viruses in | 10 |
health care workers | 10 |
min at room | 10 |
regions of the | 10 |
and replication of | 10 |
for a single | 10 |
oas and oas | 10 |
brief exposure to | 10 |
amino acid sequence | 10 |
mhc class i | 10 |
to further confirm | 10 |
a subset of | 10 |
referred to as | 10 |
onward transmission from | 10 |
recovered from horses | 10 |
was associated with | 10 |
host gene expression | 10 |
rnase l activation | 10 |
a recent study | 10 |
cells exposed to | 10 |
hek et cells | 10 |
novel potential pandemic | 10 |
tumor necrosis factor | 10 |
on the other | 10 |
important to note | 10 |
function as a | 10 |
the ko mice | 10 |
the upregulation of | 10 |
insertion of the | 10 |
used for the | 10 |
in part by | 10 |
the interaction of | 10 |
can be used | 10 |
influenza virus infections | 10 |
viruses of the | 10 |
with m pro | 10 |
of a laboratory | 10 |
data set s | 10 |
of which are | 10 |
the alphavirus supergroup | 10 |
is mediated by | 10 |
coronavirus associated with | 10 |
were determined using | 10 |
at late times | 10 |
tracheal wash fluid | 10 |
of proinflammatory cytokines | 10 |
by the use | 10 |
cd t cells | 10 |
to note that | 10 |
of the most | 10 |
northern blot analysis | 10 |
development of an | 10 |
nsp viroporin activity | 10 |
cells were plated | 10 |
had no effect | 10 |
associated with a | 10 |
were differentially expressed | 10 |
view of the | 10 |
was replaced with | 10 |
results demonstrate that | 10 |
following infection with | 10 |
that can be | 10 |
viral rna synthesis | 10 |
was confirmed by | 10 |
protein of sars | 10 |
with those of | 10 |
gain of function | 10 |
likely due to | 10 |
wide range of | 10 |
the erasmus mc | 10 |
important role in | 10 |
see materials and | 10 |
the complement pathway | 10 |
show that the | 10 |
lungs of the | 10 |
was carried out | 10 |
were normalized to | 10 |
in the first | 10 |
the discovery of | 10 |
pkr protein levels | 10 |
it is difficult | 10 |
virus between ferrets | 10 |
as a novel | 10 |
there is a | 10 |
assays were performed | 10 |
domain of the | 10 |
veroe cells were | 10 |
kindly provided by | 10 |
downregulated at hpi | 10 |
t cells in | 10 |
of the major | 10 |
identification of the | 10 |
the ferret model | 10 |
for virus replication | 10 |
the impact of | 10 |
contribute to the | 10 |
of the ferret | 10 |
given that the | 10 |
contrast to the | 10 |
medium supplemented with | 10 |
gene expression in | 10 |
included in the | 10 |
strand rna viruses | 10 |
amino acids to | 10 |
that there are | 10 |
of m protein | 10 |
response to virus | 10 |
a group of | 10 |
of pkr mrna | 10 |
regulation of the | 10 |
infection in the | 10 |
these results suggest | 10 |
and cultured in | 10 |
were transferred to | 10 |
sequence of the | 10 |
the e protein | 10 |
it is likely | 10 |
for disease control | 10 |
an rna virus | 10 |
presence of a | 10 |
we demonstrate that | 10 |
the nsp nsp | 10 |
the debate and | 9 |
were collected and | 9 |
absence of the | 9 |
modified eagle medium | 9 |
of the tree | 9 |
research on influenza | 9 |
we note that | 9 |
of small rna | 9 |
in situ hybridization | 9 |
reconstitution inflammatory syndrome | 9 |
glycans on gp | 9 |
is inhibited by | 9 |
small rna libraries | 9 |
have not been | 9 |
the spike gene | 9 |
average log fc | 9 |
immunized with combo | 9 |
of ebola virus | 9 |
in the erasmus | 9 |
the m protein | 9 |
linked immunosorbent assay | 9 |
n virus in | 9 |
the results were | 9 |
novel human coronavirus | 9 |
receptor binding site | 9 |
the virus to | 9 |
were similar to | 9 |
venezuelan equine encephalitis | 9 |
coronavirus from a | 9 |
at this time | 9 |
lower respiratory tract | 9 |
public health risks | 9 |
clinical signs of | 9 |
pl and lps | 9 |
g ml of | 9 |
be associated with | 9 |
in cynomolgus macaques | 9 |
construction of a | 9 |
available upon request | 9 |
the activity of | 9 |
viral replication and | 9 |
is shown in | 9 |
to be a | 9 |
than those of | 9 |
this suggests that | 9 |
performed using the | 9 |
of influenza viruses | 9 |
into hek t | 9 |
hpai h n | 9 |
of a single | 9 |
respiratory droplet transmission | 9 |
university of north | 9 |
of the fatty | 9 |
total rna was | 9 |
rnase l during | 9 |
was found to | 9 |
that overlapped with | 9 |
together with the | 9 |
tlr and tlr | 9 |
the transmission of | 9 |
immune response in | 9 |
the most likely | 9 |
of the other | 9 |
and incubated for | 9 |
were isolated by | 9 |
between the two | 9 |
confirmed that the | 9 |
see the supplemental | 9 |
stained with hematoxylin | 9 |
formation of dmvs | 9 |
to viral infection | 9 |
in cultured cells | 9 |
it is unclear | 9 |
were immunized with | 9 |
blood mononuclear cells | 9 |
and evolution of | 9 |
was due to | 9 |
of the epidemic | 9 |
cells were stained | 9 |
the most relevant | 9 |
length infectious cdna | 9 |
case fatality rate | 9 |
at h posttransfection | 9 |
against the sars | 9 |
demonstrate that the | 9 |
the sequences of | 9 |
titers were determined | 9 |
derived from the | 9 |
at the university | 9 |
late times postinfection | 9 |
african green monkey | 9 |
but not the | 9 |
specific t cells | 9 |
were seeded in | 9 |
the amino acid | 9 |
in the viral | 9 |
boas and boas | 9 |
used as the | 9 |
morbidity and mortality | 9 |
in accordance with | 9 |
mouth disease virus | 9 |
the m gene | 9 |
the receptor binding | 9 |
and cells were | 9 |
rna viruses and | 9 |
the endoplasmic reticulum | 9 |
active against sars | 9 |
of clinical signs | 9 |
is necessary for | 9 |
group a streptococcal | 9 |
t cell response | 9 |
igg mbcs reactive | 9 |
as described in | 9 |
used to generate | 9 |
and infected with | 9 |
loss of the | 9 |
deformed wing virus | 9 |
to induce dmv | 9 |
syndrome coronavirus in | 9 |
by using the | 9 |
the rest of | 9 |
of the pbs | 9 |
were fixed with | 9 |
the outcome of | 9 |
provide protection against | 9 |
were analyzed by | 9 |
genome sequence of | 9 |
or aerosols between | 9 |
is difficult to | 9 |
differences in the | 9 |
g ml streptomycin | 9 |
isolates recovered from | 9 |
replication in the | 9 |
against the s | 9 |
protein kinase pkr | 9 |
were defined as | 9 |
virus transmission between | 9 |
was isolated from | 9 |
rab and rab | 9 |
and vero cells | 9 |
the analysis of | 9 |
we were able | 9 |
to the sars | 9 |
equine encephalitis virus | 9 |
in this article | 9 |
of the national | 9 |
is important for | 9 |
pneumonia in saudi | 9 |
increase in the | 9 |
vivo and in | 9 |
infected with a | 9 |
with g ml | 9 |
in mice and | 9 |
s subunit of | 9 |
cell culture medium | 9 |
the other hand | 9 |
the viral rna | 9 |
the prevalence of | 9 |
avian h n | 9 |
and pandemic preparedness | 9 |
cd expression in | 9 |
for in vitro | 9 |
of the order | 9 |
addition to the | 9 |
from a man | 9 |
rnase l and | 9 |
has been previously | 9 |
induce dmv formation | 9 |
are associated with | 9 |
performed as previously | 9 |
a man with | 9 |
were unable to | 9 |
cells were exposed | 9 |
was found in | 9 |
of gp n | 9 |
concentrations of ppgpp | 9 |
of hepatitis c | 9 |
lungs of mice | 9 |
were incubated for | 9 |
expression levels of | 9 |
distribution of the | 9 |
immune reconstitution inflammatory | 9 |
and analyzed by | 9 |
in the host | 9 |
increased delivery of | 9 |
at g ml | 9 |
to study the | 9 |
in the pathogenesis | 9 |
the increase in | 9 |
h n infection | 9 |
said that they | 9 |
virus infection and | 9 |
but not by | 9 |
led to the | 9 |
not affect the | 9 |
of north carolina | 9 |
phylogenetic analysis of | 9 |
further confirm the | 9 |
most closely related | 9 |
aerosols between ferrets | 9 |
n influenza viruses | 9 |
evidence that the | 9 |
the immune system | 9 |
respiratory disease in | 9 |
differentially expressed mirnas | 9 |
to assess the | 9 |
of these viruses | 9 |
at least three | 9 |
number of years | 9 |
these data demonstrate | 9 |
membrane insertion of | 9 |
man with pneumonia | 9 |
is likely to | 9 |
for analysis of | 8 |
in the laboratory | 8 |
some of these | 8 |
reverse genetics system | 8 |
cd surface expression | 8 |
hek and vero | 8 |
well as in | 8 |
medium was replaced | 8 |
one of these | 8 |
syndrome coronavirus infection | 8 |
in a previous | 8 |
in the infected | 8 |
were included in | 8 |
of the er | 8 |
control and prevention | 8 |
were associated with | 8 |
to examine the | 8 |
which has been | 8 |
bl mefs were | 8 |
at days postinfection | 8 |
host immune response | 8 |
inhibition of the | 8 |
and wt mice | 8 |
the function of | 8 |
a range of | 8 |
was extracted from | 8 |
receptor binding domain | 8 |
in comparison to | 8 |
of putative small | 8 |
for pkr degradation | 8 |
of human parainfluenza | 8 |
to our knowledge | 8 |
increased levels of | 8 |
in mice infected | 8 |
personal protective equipment | 8 |
are critical for | 8 |
may have been | 8 |
results of the | 8 |
we confirmed that | 8 |
to those in | 8 |
elapsed time for | 8 |
of avian influenza | 8 |
in expression of | 8 |
health risks revisited | 8 |
rift valley fever | 8 |
critical role in | 8 |
after influenza virus | 8 |
of the lungs | 8 |
indicate that the | 8 |
is known that | 8 |
processing of the | 8 |
rather than the | 8 |
expression of nsp | 8 |
recombinant parainfluenza virus | 8 |
debate and research | 8 |
deposited in genbank | 8 |
in case of | 8 |
were analyzed for | 8 |
the site of | 8 |
first time that | 8 |
transmission between ferrets | 8 |
of the hn | 8 |
cleavage of the | 8 |
and h postinfection | 8 |
been reported in | 8 |
were grown in | 8 |
material is available | 8 |
be able to | 8 |
of porcine epidemic | 8 |
were performed with | 8 |
infection in cis | 8 |
this work was | 8 |
p x ko | 8 |
were used as | 8 |
min of incubation | 8 |
the national institute | 8 |
h at room | 8 |
compared to mock | 8 |
exception of the | 8 |
basis of the | 8 |
insights into the | 8 |
hn dimer interface | 8 |
were measured by | 8 |
mirna expression changes | 8 |
of the first | 8 |
could not be | 8 |
levels of igg | 8 |
polymerase chain reaction | 8 |
to test whether | 8 |
sequencing of the | 8 |
dmem supplemented with | 8 |
has previously been | 8 |
need to be | 8 |
text s in | 8 |
cells were seeded | 8 |
human airway epithelial | 8 |
a factor of | 8 |
binding of niv | 8 |
supplemental material is | 8 |
lungs of c | 8 |
and treated with | 8 |
it is known | 8 |
hematoxylin and eosin | 8 |
of vero cells | 8 |
in agreement with | 8 |
responses to sars | 8 |
and does not | 8 |
we examined the | 8 |
are present in | 8 |
did not affect | 8 |
available in the | 8 |
a mouse model | 8 |
was performed to | 8 |
in this model | 8 |
by confocal microscopy | 8 |
difference between the | 8 |
tissues of the | 8 |
to work on | 8 |
erasmus mc facility | 8 |
combo formulated with | 8 |
from his laboratory | 8 |
but did not | 8 |
number of reads | 8 |
as early as | 8 |
cd t cell | 8 |
als p and | 8 |
play a role | 8 |
the virus was | 8 |
with pl flux | 8 |
were fixed in | 8 |
ph n and | 8 |
of the university | 8 |
were generated using | 8 |
lower than that | 8 |
nature of the | 8 |
samples collected from | 8 |
s protein of | 8 |
consistent with our | 8 |
in nsp and | 8 |
in the er | 8 |
centers for disease | 8 |
to multiple nucleoside | 8 |
of the wt | 8 |
as the primary | 8 |
were analyzed using | 8 |
furin cleavage site | 8 |
weight loss and | 8 |
the functions of | 8 |
mice were infected | 8 |
mutation in the | 8 |
to the small | 8 |
of the family | 8 |
and mortality in | 8 |
were performed as | 8 |
bmdcs from sfb | 8 |
the sensitivity of | 8 |
ko and wt | 8 |
deletion of the | 8 |
probability of onward | 8 |
contact with the | 8 |
appears to be | 8 |
samples were collected | 8 |
was purchased from | 8 |
is likely that | 8 |
by using a | 8 |
in the ko | 8 |
of the ifn | 8 |
virus replication and | 8 |
to have been | 8 |
infection with influenza | 8 |
the lethal dose | 8 |
were stimulated with | 8 |
at day p | 8 |
of pandemic influenza | 8 |
to test the | 8 |
accession number gse | 8 |
supplemented with fbs | 8 |
human and mouse | 8 |
upper and lower | 8 |
performed to detect | 8 |
the infectivity and | 8 |
three times with | 8 |
medium was added | 8 |
analysis was performed | 8 |
and it is | 8 |
of the innate | 8 |
the primary antibody | 8 |
of c bl | 8 |
based on a | 8 |
risks and benefits | 8 |
that at least | 8 |
and research pause | 8 |
at the level | 8 |
rnase l in | 8 |
of a potential | 8 |
of infected cells | 8 |
of the annotated | 8 |
specificity of the | 8 |
at least two | 8 |
strongly suggest that | 8 |
have also been | 8 |
receptor for the | 8 |
similar to the | 8 |
affected by the | 8 |
been reported to | 8 |
the distribution of | 8 |
after infection with | 8 |
of the disease | 8 |
is sufficient to | 8 |
in ml of | 8 |
significantly higher than | 8 |
the large number | 8 |
is available online | 8 |
and nsp are | 8 |
is a major | 8 |
the hypothesis that | 8 |
the increased delivery | 8 |
we used the | 8 |
that they are | 8 |
in the network | 8 |
western blot analysis | 8 |
cov m protein | 8 |
a measure of | 8 |
it would be | 8 |
a large number | 8 |
to be highly | 8 |
elevation of ca | 8 |
to generate the | 8 |
we investigated the | 8 |
mhc class ii | 8 |
we demonstrated that | 8 |
this time point | 8 |
by the virus | 8 |
cov infectious cdna | 8 |
from those of | 8 |
supported by the | 8 |
a highly pathogenic | 8 |
and then incubated | 8 |
in the literature | 8 |
it will be | 8 |
depends on the | 8 |
transcriptome sequencing analysis | 8 |
seem to be | 8 |
were expressed in | 8 |
a member of | 8 |
a model of | 8 |
isolated from humans | 8 |
weeks after the | 8 |
important for the | 8 |
at hpi and | 8 |
has also been | 8 |
we showed that | 8 |
w a mutant | 8 |
with hematoxylin and | 8 |
temperature for min | 8 |
to bind to | 8 |
available online only | 8 |
using the following | 8 |
in the hn | 8 |
were found in | 8 |
the same as | 8 |
higher levels of | 8 |
infection in mice | 8 |
and should be | 8 |
in the serum | 8 |
we have shown | 8 |
disease control and | 8 |
was able to | 8 |
response to the | 8 |
an outbreak of | 8 |
response in the | 8 |
antigen presentation pathway | 8 |
murine hepatitis virus | 8 |
glycan array screening | 8 |
in the nsp | 8 |
viruses isolated from | 8 |
is an important | 8 |
lungs of sars | 8 |
transmission of the | 8 |
formation of the | 8 |
be required to | 8 |
glycans on the | 7 |
structural and functional | 7 |
cell responses against | 7 |
suggesting that it | 7 |
e protein in | 7 |
in the wild | 7 |
a decrease in | 7 |
functional receptor for | 7 |
and development of | 7 |
is a functional | 7 |
of the manuscript | 7 |
have been shown | 7 |
animal care and | 7 |
that the virus | 7 |
represents the mean | 7 |
was analyzed by | 7 |
do not know | 7 |
driving force for | 7 |
infected cells and | 7 |
we determined the | 7 |
amino acid identity | 7 |
rectal swabs were | 7 |
mrna bound to | 7 |
the reaction products | 7 |
the effectiveness of | 7 |
mice compared to | 7 |
effects of the | 7 |
its role in | 7 |
were harvested at | 7 |
the history of | 7 |
to the human | 7 |
each time point | 7 |
airway epithelial cells | 7 |
the virus and | 7 |
well of a | 7 |
a p value | 7 |
of cynomolgus macaques | 7 |
was funded by | 7 |
with ml of | 7 |
differences between the | 7 |
infectious cdna of | 7 |
m pore size | 7 |
of the coronavirus | 7 |
susceptible to the | 7 |
infection with sars | 7 |
of differentially expressed | 7 |
at a time | 7 |
mechanisms by which | 7 |
revealed that the | 7 |
trsv isolates from | 7 |
to generate a | 7 |
in our study | 7 |
samples from the | 7 |
would be expected | 7 |
the idea that | 7 |
implications for the | 7 |
our data suggest | 7 |
titers in nasal | 7 |
a receptor for | 7 |
does not necessarily | 7 |
to the viral | 7 |
each of these | 7 |
dependent rna polymerases | 7 |
lung injury and | 7 |
upregulation of the | 7 |
protease inhibitor cocktail | 7 |
patients with covid | 7 |
s proteins of | 7 |
of rna release | 7 |
of p x | 7 |
loci that overlapped | 7 |
infected cells were | 7 |
to ensure that | 7 |
at the indicated | 7 |
for entry into | 7 |
the changes in | 7 |
genes de at | 7 |
suggested that the | 7 |
class of small | 7 |
multiple nucleoside analogues | 7 |
hdpp ki mice | 7 |
not in the | 7 |
department of health | 7 |
the veroe cells | 7 |
of the e | 7 |
the international committee | 7 |
infected with pfu | 7 |
the combination of | 7 |
in the ferret | 7 |
to the same | 7 |
genes of unknown | 7 |
viruses in the | 7 |
is present in | 7 |
biosafety and biosecurity | 7 |
with severe acute | 7 |
in hela cells | 7 |
infection with a | 7 |
into vero cells | 7 |
small nucleolar rnas | 7 |
h n challenge | 7 |
after h of | 7 |
the st strain | 7 |
in the human | 7 |
absence of complement | 7 |
of the debate | 7 |
or h n | 7 |
in at least | 7 |
small rnas and | 7 |
the value of | 7 |
infected p x | 7 |
of the hcov | 7 |
transmission via respiratory | 7 |
protein kinase r | 7 |
with nl virus | 7 |
veroe cells and | 7 |
serum samples were | 7 |
performed on a | 7 |
small rnas are | 7 |
the hn protein | 7 |
the origin of | 7 |
to induce the | 7 |
the result of | 7 |
bl j and | 7 |
do not necessarily | 7 |
after min of | 7 |
seen in the | 7 |
a single lab | 7 |
not appear to | 7 |
we conclude that | 7 |
cov and mers | 7 |
we do not | 7 |
a community lai | 7 |
the virus titers | 7 |
as in the | 7 |
in the mld | 7 |
thought to be | 7 |
and middle east | 7 |
influenza risk assessment | 7 |
and lower respiratory | 7 |
in some cases | 7 |
quantitative reverse transcription | 7 |
analyses were performed | 7 |
herpes simplex virus | 7 |
small number of | 7 |
not seem to | 7 |
infected or infected | 7 |
signs of respiratory | 7 |
bone marrow cells | 7 |
of the interferon | 7 |
bat roni cells | 7 |
resuspended in l | 7 |
pedv pc a | 7 |
complete genome sequence | 7 |
by northern blot | 7 |
cells were maintained | 7 |
on the same | 7 |
followed by a | 7 |
pseudotyped viral particles | 7 |
cov and hcov | 7 |
we show that | 7 |
taxonomy of viruses | 7 |
hn h q | 7 |
length cdna clone | 7 |
was mixed with | 7 |
supported in part | 7 |
studies on influenza | 7 |
found in a | 7 |
small rna locus | 7 |
of the authors | 7 |
into hek et | 7 |
is not required | 7 |
students and postdoctoral | 7 |
with acute respiratory | 7 |
interferon regulatory factor | 7 |
as part of | 7 |
is similar to | 7 |
high concentrations of | 7 |
total number of | 7 |
tobacco ringspot virus | 7 |
value represents the | 7 |
may function as | 7 |
supernatants were harvested | 7 |
of the samples | 7 |
accordance with the | 7 |
in conjunction with | 7 |
and adaptive immune | 7 |
research of concern | 7 |
use of highly | 7 |
isolates were recovered | 7 |
the next day | 7 |
rnase l pathway | 7 |
data show that | 7 |
the finding that | 7 |
from each cluster | 7 |
of streptococcus equi | 7 |
was purified from | 7 |
lead to the | 7 |
in rpmi medium | 7 |
not essential for | 7 |
in roni cells | 7 |
the structure of | 7 |
of the full | 7 |
have been described | 7 |
that were not | 7 |
was extracted using | 7 |
the notion that | 7 |
to calculate the | 7 |
number of de | 7 |
select agent theft | 7 |
transfected cells were | 7 |
we thank the | 7 |
to endo h | 7 |
context of the | 7 |
as a result | 7 |
to severe acute | 7 |
as a vaccine | 7 |
enhanced green fluorescent | 7 |
resulted in the | 7 |
and loss of | 7 |
the crystal structure | 7 |
from the cell | 7 |
and table s | 7 |
and postdoctoral fellows | 7 |
that this is | 7 |
host and viral | 7 |
of this virus | 7 |
used to identify | 7 |
and use committee | 7 |
ability of the | 7 |
prior to the | 7 |
the concentration of | 7 |
we were unable | 7 |
of potential pandemic | 7 |
coexpression of sars | 7 |
rna copy numbers | 7 |
was subjected to | 7 |
indicating that m | 7 |
functional analysis of | 7 |
caused by a | 7 |
the tigers and | 7 |
was calculated as | 7 |
than in those | 7 |
for activation of | 7 |
with l of | 7 |
resulting in the | 7 |
overall clinical scores | 7 |
in the golgi | 7 |
sufficient to induce | 7 |
the frequency of | 7 |
a result of | 7 |
the ancestor of | 7 |
results suggested that | 7 |
for binding to | 7 |
work was supported | 7 |
at hpi in | 7 |
of which were | 7 |
the authors and | 7 |
we could detect | 7 |
and did not | 7 |
h n avian | 7 |
via posttranslational control | 7 |
function of the | 7 |
or influenza virus | 7 |
vero cells were | 7 |
case of lai | 7 |
protective efficacy of | 7 |
of the t | 7 |
a function of | 7 |
with a anhui | 7 |
j and c | 7 |
genetic analysis of | 7 |
infection and the | 7 |
virus a anhui | 7 |
concentrations of the | 7 |
in this report | 7 |
these results demonstrate | 7 |
it is a | 7 |
of human respiratory | 7 |
the sars coronavirus | 7 |
severe respiratory disease | 7 |
of test compounds | 7 |
to be the | 7 |
the rbd and | 7 |
the wt mice | 7 |
immune responses in | 7 |
play an important | 7 |
of the four | 7 |
entry mediated by | 7 |
s b and | 7 |
characteristics of the | 7 |
infection with hcov | 7 |
to address this | 7 |
total pkr mrna | 7 |
within the gp | 7 |
for the formation | 7 |
influenza virus in | 7 |
stranded rna viruses | 7 |
the mechanism of | 7 |
data were analyzed | 7 |
than that of | 7 |
the quality of | 7 |
supported by nih | 7 |
and can be | 7 |
of the s | 7 |
is not known | 7 |
necrosis factor alpha | 7 |
animal and human | 7 |
a mixture of | 7 |
the potential for | 7 |
receptor p x | 7 |
virus ns protein | 7 |
the driving force | 7 |
of mouse adenovirus | 7 |
innate immune responses | 7 |
consistent with a | 7 |
impact of the | 7 |
it was shown | 7 |
associated molecular patterns | 7 |
change in the | 7 |
a lab escape | 7 |
memory b cell | 7 |
h n in | 7 |
is used to | 7 |
clinical samples and | 7 |
we sought to | 7 |
plays a role | 7 |
of health and | 7 |
the control of | 7 |
virus transmission via | 7 |
are predicted to | 7 |
was performed in | 7 |
from clinical samples | 7 |
result of a | 7 |
and public health | 7 |
was performed as | 7 |
a vaccine candidate | 7 |
side of the | 7 |
that some of | 7 |
that m protein | 7 |
were derived from | 7 |
with influenza a | 7 |
of the ebola | 7 |
protein was detected | 7 |
on ebov gp | 7 |
the consequences of | 7 |
in the gp | 7 |
n virus between | 7 |
a study of | 7 |
de at hpi | 7 |
in the cytoplasm | 7 |
a functional receptor | 7 |
reaction products were | 7 |
the glycan determinants | 7 |
in wt cells | 7 |
hold at b | 6 |
are involved in | 6 |
was amplified by | 6 |
and centrifuged at | 6 |
and the number | 6 |
that the oas | 6 |
were expressed with | 6 |
consistent with this | 6 |
be used for | 6 |
not necessarily reflect | 6 |
was measured by | 6 |
vero e cells | 6 |
two time points | 6 |
were classified as | 6 |
hattori et al | 6 |
removed from the | 6 |
r sv mefs | 6 |
human cases of | 6 |
combined with the | 6 |
infected ko mice | 6 |
infection of a | 6 |
to this end | 6 |
and used for | 6 |
infection of caco | 6 |
in parallel with | 6 |
upstream of rna | 6 |
protein in trans | 6 |
other bee viruses | 6 |
the views of | 6 |
on the glycan | 6 |
university of washington | 6 |
replication and pathogenesis | 6 |
the elevation of | 6 |
purified using a | 6 |
mice were euthanized | 6 |
and pathogenesis of | 6 |
lab escape of | 6 |
that they were | 6 |
to facilitate the | 6 |
disease in humans | 6 |
accumulation of the | 6 |
viral replication in | 6 |
on taxonomy of | 6 |
of both the | 6 |
majority of the | 6 |
mm by mm | 6 |
s b in | 6 |
for more than | 6 |
cd ko mice | 6 |
pandemic influenza viruses | 6 |
in the evolution | 6 |
in human airway | 6 |
affinity of the | 6 |
of cytoplasmic ca | 6 |
posttranslational control of | 6 |
and human services | 6 |
of bone marrow | 6 |
studies in the | 6 |
of the middle | 6 |
and in the | 6 |
data demonstrate that | 6 |
the cdna clone | 6 |
the transduction of | 6 |
the interaction between | 6 |
antibody responses to | 6 |
the internal proteins | 6 |
not result in | 6 |
was performed for | 6 |
of infectious diseases | 6 |
in the gut | 6 |
proteins that are | 6 |
be used as | 6 |
at day postinfection | 6 |
of the original | 6 |
amplified by pcr | 6 |
the icelandic horse | 6 |
to ph n | 6 |
be involved in | 6 |
the probability that | 6 |
of mhc class | 6 |
immunization with piv | 6 |
cultured in rpmi | 6 |
glycan cap and | 6 |
time reverse transcription | 6 |
were performed on | 6 |
cells with a | 6 |
with h n | 6 |
gp and furin | 6 |
reports in the | 6 |
amino acid sequences | 6 |
the dsrna viruses | 6 |
it does not | 6 |
our data indicate | 6 |
the molecular mechanisms | 6 |
from each animal | 6 |
defined by the | 6 |
caused by the | 6 |
a role for | 6 |
of complement signaling | 6 |
of the cell | 6 |
infected mice were | 6 |
whether or not | 6 |
s a and | 6 |
in these studies | 6 |
viral rna was | 6 |
with regard to | 6 |
a virus infection | 6 |
dominant negative mutants | 6 |
have to be | 6 |
evaluation of the | 6 |
has been proposed | 6 |
protection against e | 6 |
on the viral | 6 |
evolution of rna | 6 |
than that in | 6 |
the results from | 6 |
may not be | 6 |
loss and release | 6 |
of e protein | 6 |
these genes were | 6 |
pl synthesis pathways | 6 |
binding site ii | 6 |
virus infections in | 6 |
small interfering rna | 6 |
at both time | 6 |
against severe acute | 6 |
were selected for | 6 |
properties of the | 6 |
piv expressing mers | 6 |
using superscript iii | 6 |
primary peritoneal macrophages | 6 |
h n ha | 6 |
genbank accession number | 6 |
epidemic of respiratory | 6 |
performed as described | 6 |
can also be | 6 |
is that the | 6 |
on at least | 6 |
and tracheal wash | 6 |
rpmi medium supplemented | 6 |
from the full | 6 |
course of infection | 6 |
as a consequence | 6 |
to each other | 6 |
as a function | 6 |
red blood cells | 6 |
reactive igg mbcs | 6 |
at the site | 6 |
purinergic receptor p | 6 |
be due to | 6 |
for min to | 6 |
of infection with | 6 |
be important for | 6 |
a previous study | 6 |
seasonal influenza viruses | 6 |
disruption of the | 6 |
for the virus | 6 |
data have been | 6 |
the antigen presentation | 6 |
be sufficient to | 6 |
to the formation | 6 |
times with pbs | 6 |
libraries were prepared | 6 |
in less than | 6 |
cells were grown | 6 |
the most abundant | 6 |
putative small rnas | 6 |
amino acid residues | 6 |
significant increase in | 6 |
the magnitude of | 6 |
analysis of variance | 6 |
deep sequencing of | 6 |
infected with nl | 6 |
small rnas from | 6 |
study of the | 6 |
the elapsed time | 6 |
committee on taxonomy | 6 |
enterica serovar typhi | 6 |
analyzed for the | 6 |
when march was | 6 |
to provide protection | 6 |
of igg mbcs | 6 |
reported to be | 6 |
for growth in | 6 |
to better understand | 6 |
are likely to | 6 |
later times postinfection | 6 |
to be important | 6 |
were analyzed with | 6 |
genome sequences of | 6 |
transmission of h | 6 |
infection results in | 6 |
in cells infected | 6 |
graduate students and | 6 |
igg titers against | 6 |
ends of the | 6 |
bound to the | 6 |
convalescent subjects than | 6 |
lethal dose of | 6 |
and analysis of | 6 |
nsp or nsp | 6 |
into the cell | 6 |
could be detected | 6 |
challenge in mice | 6 |
that have been | 6 |
tmprss cells were | 6 |
e b k | 6 |
influenza virus ns | 6 |
be related to | 6 |
rbd and s | 6 |
out of the | 6 |
increased resistance to | 6 |
expression of gp | 6 |
in nasal swabs | 6 |
the virus in | 6 |
the nature of | 6 |
during viral infection | 6 |
in our analysis | 6 |
small rna cloning | 6 |
were allowed to | 6 |
and epa p | 6 |
health and human | 6 |
assembly of the | 6 |
to the lack | 6 |
determined using the | 6 |
and veroe tmprss | 6 |
genes related to | 6 |
activated protein kinase | 6 |
for providing the | 6 |
as a potential | 6 |
under conditions of | 6 |
like receptor signaling | 6 |
undetected or unreported | 6 |
for dmv formation | 6 |
of ebov gp | 6 |
pkr depletion by | 6 |
level of the | 6 |
primer sequences are | 6 |
these data indicate | 6 |
with g of | 6 |
could have been | 6 |
of the pandemic | 6 |
urokinase pathway in | 6 |
an animal model | 6 |
of cd expression | 6 |
derived small rnas | 6 |
the d g | 6 |
human respiratory syncytial | 6 |
in a dose | 6 |
international committee on | 6 |
washed with pbs | 6 |
valley fever virus | 6 |
infected and infected | 6 |
compared with those | 6 |
necessarily reflect the | 6 |
higher than the | 6 |
that did not | 6 |
possible that the | 6 |
of a new | 6 |
vero a and | 6 |
viruses evolved from | 6 |
gene expression profiles | 6 |
m gene products | 6 |
rna was harvested | 6 |
to b in | 6 |
were significantly higher | 6 |
mice were used | 6 |
are not well | 6 |
among rna viruses | 6 |
infected with mers | 6 |
molecular basis for | 6 |
of group a | 6 |
about the debate | 6 |
infected cells was | 6 |
nonessential amino acids | 6 |
min and then | 6 |
levels of the | 6 |
the entry of | 6 |
not statistically significant | 6 |
the influence of | 6 |
previous work has | 6 |
in this work | 6 |
in humans and | 6 |
histocompatibility complex class | 6 |
levels of pkr | 6 |
with cryptococcal meningitis | 6 |
n avian influenza | 6 |
sought to determine | 6 |
the genome of | 6 |
and subjected to | 6 |
deviation from three | 6 |
and ebola virus | 6 |
by the unc | 6 |
in the face | 6 |
adaptive immune response | 6 |
that activation of | 6 |
is a common | 6 |
protein expression in | 6 |
entry depends on | 6 |
to address the | 6 |
incubated for min | 6 |
of membrane synthesis | 6 |
by quantitative reverse | 6 |
glycans attached to | 6 |
i and ii | 6 |
the availability of | 6 |
broad range of | 6 |
and the cells | 6 |
also contribute to | 6 |
dynamin and clathrin | 6 |
appear to have | 6 |
and virulence of | 6 |
visualization of the | 6 |
leads to a | 6 |
of sars coronavirus | 6 |
be explained by | 6 |
differences were observed | 6 |
listed in table | 6 |
the causative agent | 6 |
to the er | 6 |
the observation that | 6 |
of zippered er | 6 |
for detection of | 6 |
is independent of | 6 |
small rnas that | 6 |
were not detected | 6 |
of the orf | 6 |
which are not | 6 |
cells were collected | 6 |
was analyzed using | 6 |
the purinergic receptor | 6 |
viruses that are | 6 |
and others have | 6 |
only a few | 6 |
sequencing analysis of | 6 |
serve as a | 6 |
rna loci that | 6 |
may have a | 6 |
small rna transcriptome | 6 |
pathogenic h n | 6 |
of less than | 6 |
henipavirus infection in | 6 |
suppression of t | 6 |
there has been | 6 |
appeared to be | 6 |
we are grateful | 6 |
genes associated with | 6 |
old c bl | 6 |
that results in | 6 |
oas protein expression | 6 |
of incubation at | 6 |
in influenza virus | 6 |
the total number | 6 |
each value represents | 6 |
origin influenza a | 6 |
that could be | 6 |
in the tigers | 6 |
an analysis of | 6 |
b in the | 6 |
during viral isolation | 6 |
cells pretreated with | 6 |
subjects than in | 6 |
of igg against | 6 |
in veroe cells | 6 |
this is not | 6 |
seasonal h n | 6 |
the transfected cells | 6 |
proteins such as | 6 |
our results suggest | 6 |
allowed us to | 6 |
the set of | 6 |
and release reports | 6 |
diffuse alveolar damage | 6 |
samples were analyzed | 6 |
reported that the | 6 |
human and animal | 6 |
factors associated with | 6 |
at least in | 6 |
involving pathogens with | 6 |
bat and human | 6 |
lymphocytic choriomeningitis virus | 6 |
in line with | 6 |
in a mixture | 6 |
influenza virus and | 6 |
lgi network of | 6 |
did not significantly | 6 |
absence of c | 6 |
cell activation and | 6 |
of deformed wing | 6 |
of the genes | 6 |
that were differentially | 6 |
see also table | 6 |
cd expression on | 6 |
cov spike protein | 6 |
mouse reference genome | 6 |
infections in the | 6 |
these results suggested | 6 |
not have a | 6 |
size of the | 6 |
viral isolates were | 6 |
effect of the | 6 |
stranded rna virus | 6 |
in pbs with | 6 |
for at least | 6 |
different from those | 6 |
the active site | 6 |
may be used | 6 |
of the cellular | 6 |
upstream of the | 6 |
calculated using the | 6 |
were calculated as | 6 |
use research of | 6 |
correlates of protection | 6 |
the kinetics of | 6 |
in the genome | 6 |
of the predicted | 6 |
of neutralizing antibodies | 6 |
are grateful to | 6 |
the apical surface | 6 |
against invasive gas | 6 |
loci overlapped with | 6 |
of honey bee | 6 |
used in this | 6 |
for min with | 6 |
can lead to | 6 |
of a h | 6 |
bacterial and viral | 6 |
cov infection in | 6 |
has been observed | 6 |
to interact with | 6 |
were approved by | 6 |
ng of pcaggs | 6 |
during influenza virus | 6 |
gene set enrichment | 6 |
is not the | 6 |
increased doses of | 6 |
upper respiratory tract | 6 |
and cloned into | 6 |
reported to the | 6 |
to analyze the | 6 |
and do not | 6 |
during the epidemic | 6 |
more similar to | 6 |
at and h | 6 |
spread of sars | 6 |
to be associated | 6 |
dependent on the | 6 |
the inhibition of | 6 |
with the sars | 6 |
proteins encoded by | 6 |
in the natural | 6 |
associated with severe | 6 |
fuscus skin fibroblasts | 6 |
the egyptian rousette | 6 |
of the total | 6 |
by addition of | 6 |
the major branches | 6 |
in the research | 6 |
a virus in | 6 |
a and huh | 6 |
in a single | 6 |
for each of | 6 |
nd nd nd | 6 |
this type of | 6 |
each cluster were | 6 |
by nih grant | 6 |
release reports in | 6 |
no significant differences | 6 |
a novel human | 6 |
bl mice were | 6 |
glycans in the | 6 |
in both the | 6 |
to detect the | 6 |
that are not | 6 |
observed a significant | 6 |
the differences in | 6 |
were identified in | 6 |
were washed and | 6 |
molecular basis of | 6 |
with combo smq | 6 |
the circular profiles | 6 |
in ferrets and | 6 |
case of the | 6 |
the extent of | 6 |
of viral infection | 6 |
were isolated from | 6 |
we also examined | 6 |
seasonal influenza virus | 6 |
were transiently transfected | 6 |
is critical for | 6 |
the host immune | 6 |
provided by the | 6 |
gene expression omnibus | 6 |
infections in humans | 6 |
aspects of the | 6 |
the ratio of | 6 |
a new coronavirus | 6 |
from three independent | 6 |
ucsc genome browser | 6 |
highly pathogenic influenza | 6 |
the cell culture | 6 |
of the m | 6 |
may be a | 6 |
eptesicus fuscus skin | 6 |
required for pkr | 6 |
the result is | 6 |
parainfluenza virus expressing | 6 |
in the lethal | 6 |
both time points | 6 |
standard deviation from | 6 |
molecularly based surveillance | 6 |
and found that | 6 |
structural basis for | 6 |
vero cells infected | 6 |
the presence and | 6 |
the sequence of | 6 |
resistance to multiple | 6 |
perspective on the | 6 |
cells of the | 6 |
h n vaccine | 6 |
were present in | 6 |
in the rna | 6 |
proteins of the | 6 |
binding of the | 6 |
a broad range | 6 |
variation in the | 6 |
been reported that | 6 |
the infectivity of | 6 |
genomic characterization of | 6 |
of the severe | 6 |
was not detected | 6 |
in this regard | 6 |
could be used | 6 |
more sensitive to | 6 |
for human emergence | 6 |
in hong kong | 6 |
diversity of rna | 6 |
protein of the | 6 |
this study was | 6 |
of the genomic | 6 |
any of the | 6 |
the face of | 6 |
highly pathogenic h | 6 |
rna was purified | 6 |
we evaluated the | 6 |
as assessed by | 6 |
with the presence | 6 |
binding of n | 6 |
salmonella enterica serovar | 6 |
in text s | 6 |
k r sv | 6 |
is the first | 6 |
induced acute lung | 6 |
dc in the | 6 |
a review of | 6 |
cytopathic effect of | 6 |
in recent years | 6 |
the background of | 6 |
likely that the | 6 |
infected with influenza | 6 |
hcv patient plasma | 6 |
of pbs u | 6 |
as a negative | 6 |
of the infected | 6 |
sequences of the | 6 |
in the study | 6 |
and benefits of | 6 |
of the membrane | 6 |
in the virus | 6 |
gene expression data | 6 |
effective against the | 6 |
viroporin domain is | 6 |
influenza h n | 6 |
of viral replication | 6 |
and ph n | 6 |
and influenza a | 6 |
dependent protein kinase | 6 |
not well understood | 6 |
well plates were | 6 |
to late endosomes | 6 |
which have been | 6 |
determined by plaque | 6 |
monitoring select agent | 6 |
the capacity of | 6 |
with co for | 5 |
were predicted to | 5 |
address this issue | 5 |
prompted us to | 5 |
discovery of a | 5 |
isolation and characterization | 5 |
and varroa mites | 5 |
collected from the | 5 |
been observed in | 5 |
involved in this | 5 |
of the individual | 5 |
such as influenza | 5 |
indicating that they | 5 |
pc a strain | 5 |
the choice of | 5 |
the ucsc genome | 5 |
a significant increase | 5 |
a common ancestor | 5 |
serum samples from | 5 |
determine if the | 5 |
are also likely | 5 |
m and np | 5 |
rna viruses in | 5 |
viruses and their | 5 |
with a full | 5 |
in vitro stimulation | 5 |
in the number | 5 |
proteins in the | 5 |
a potential pandemic | 5 |
to the lung | 5 |
as indicated by | 5 |
branch consists of | 5 |
host range and | 5 |
it was recently | 5 |
of the small | 5 |
catalytic domain of | 5 |
reverse genetics with | 5 |
the appearance of | 5 |
is the most | 5 |
memory t cells | 5 |
ml of penicillin | 5 |
human infections in | 5 |
better understanding of | 5 |
as described for | 5 |
viral titers were | 5 |
was required for | 5 |
to investigate whether | 5 |
early and late | 5 |
which can be | 5 |
infection of the | 5 |
based on their | 5 |
alteration of the | 5 |
human coronavirus emc | 5 |
to weeks after | 5 |
rna from the | 5 |
to rule out | 5 |
sh and hn | 5 |
but not with | 5 |
set enrichment analysis | 5 |
the infectious cdna | 5 |
min hold at | 5 |
by expression of | 5 |
for the generation | 5 |
are shown as | 5 |
of mycobacterium tuberculosis | 5 |
related to those | 5 |
nucleotides of the | 5 |
of human immunodeficiency | 5 |
mock infected or | 5 |
of the families | 5 |
n h n | 5 |
has led to | 5 |
influenza viruses and | 5 |
have been used | 5 |
days and postinfection | 5 |
for the emerging | 5 |
risk and elapsed | 5 |
and nsp were | 5 |
and n proteins | 5 |
generation of a | 5 |
was performed with | 5 |
were downloaded from | 5 |
use of the | 5 |
of the research | 5 |
these and other | 5 |
b cell responses | 5 |
tissue culture infective | 5 |
public health benefits | 5 |
calculation of risk | 5 |
the mrna level | 5 |
of a conserved | 5 |
to the development | 5 |
associated with acute | 5 |
pellets were resuspended | 5 |
transiently transfected into | 5 |
of the test | 5 |
supernatants were collected | 5 |
we speculate that | 5 |
and the virus | 5 |
of a lab | 5 |
mg kg of | 5 |
for viral rna | 5 |
derived from mice | 5 |
ebov gp and | 5 |
microrna host genes | 5 |
there may be | 5 |
colonized with sfb | 5 |
quality of the | 5 |
have demonstrated that | 5 |
as a measure | 5 |
ebov entry into | 5 |
immunized with pfu | 5 |
are important for | 5 |
alignment of the | 5 |
mutants were expressed | 5 |
were related to | 5 |
neutrophils in the | 5 |
cov ma pathogenesis | 5 |
the capsid protein | 5 |
have the same | 5 |
the scientific community | 5 |
to be more | 5 |
to a global | 5 |
rna viruses have | 5 |
the s proteins | 5 |
in combination with | 5 |
were euthanized at | 5 |
of the arterivirus | 5 |
functional and structural | 5 |
the catalytic domain | 5 |
the sample was | 5 |
for murine coronavirus | 5 |
genetic changes inventory | 5 |
lectin binding intensity | 5 |
significantly higher in | 5 |
of plant viruses | 5 |
the size of | 5 |
dipeptidyl peptidase is | 5 |
measure of the | 5 |
e orf and | 5 |
were washed with | 5 |
from sample sc | 5 |
in vero a | 5 |
of pkr is | 5 |
compared with the | 5 |
comparative analysis of | 5 |
cell culture supernatants | 5 |
pkr mrna bound | 5 |
as a tool | 5 |
cellular immune responses | 5 |
significant reduction in | 5 |
from patients with | 5 |
u ml of | 5 |
and may be | 5 |
also found that | 5 |
positive for sars | 5 |
many of these | 5 |
pathogenesis of influenza | 5 |
or in the | 5 |
highlighted in the | 5 |
drugs against sars | 5 |
that the host | 5 |
novel coronavirus associated | 5 |
central nervous system | 5 |
higher than those | 5 |
epa p to | 5 |
of the rdrps | 5 |
unable to detect | 5 |
and identification of | 5 |
significant differences were | 5 |
is equal to | 5 |
and have been | 5 |
in materials and | 5 |
mild to marked | 5 |
a source of | 5 |
the receptor for | 5 |
can serve as | 5 |
as it is | 5 |
l volume of | 5 |
in the p | 5 |
inflammatory cells in | 5 |
were incubated at | 5 |
characterized by the | 5 |
to the plasma | 5 |
antiviral activity by | 5 |
of the population | 5 |
and c a | 5 |
cov and influenza | 5 |
previously reported that | 5 |
of viral proteins | 5 |
this was not | 5 |
nsp nsp cleavage | 5 |
risk assessment of | 5 |
of virus replication | 5 |
cynomolgus macaques inoculated | 5 |
in the integral | 5 |
acp and c | 5 |
was based on | 5 |
its w a | 5 |
ph n np | 5 |
clathrin heavy chain | 5 |
that were recovered | 5 |
prevalence of trsv | 5 |
members of a | 5 |
at to dpi | 5 |
a better understanding | 5 |
the first step | 5 |
was recently shown | 5 |
was added at | 5 |
a reverse genetics | 5 |
national center for | 5 |
analyzed using the | 5 |
the opposing monomer | 5 |
h q mutation | 5 |
such as sars | 5 |
decrease in the | 5 |
recombinant viruses were | 5 |
that the m | 5 |
spr analysis of | 5 |
the region of | 5 |
ph n m | 5 |
the process of | 5 |
the membrane structures | 5 |
from horses at | 5 |
red infectious center | 5 |
this is the | 5 |
homology at the | 5 |
stained in green | 5 |
complement system is | 5 |
for development of | 5 |
nih national institute | 5 |
human infection with | 5 |
result is representative | 5 |
were detected by | 5 |
of body weight | 5 |
by pcr using | 5 |
the design of | 5 |
in a mouse | 5 |
no change in | 5 |
associated with an | 5 |
indicates that the | 5 |
a murine model | 5 |
was cotransfected with | 5 |
of infected mice | 5 |
secondary bacterial infections | 5 |
are as follows | 5 |
a consequence of | 5 |
vero cells or | 5 |
icelandic veterinary institute | 5 |
the antiviral activity | 5 |
and analyzed using | 5 |
g of pcmv | 5 |
interaction with the | 5 |