This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.
bigram | frequency |
---|---|
cancer cells | 226 |
amino acid | 181 |
drug discovery | 178 |
biscao water | 175 |
antiviral activity | 156 |
virtual screening | 151 |
drug design | 142 |
topoisomerase i | 137 |
cell lines | 125 |
active site | 122 |
amino acids | 122 |
gold nanoparticles | 120 |
dna aptamers | 115 |
kcal mol | 111 |
silver nanoparticles | 110 |
formyl peptide | 109 |
influenza virus | 104 |
nmr spectroscopy | 102 |
cell death | 100 |
molecular docking | 97 |
cancer cell | 97 |
binding energy | 93 |
breast cancer | 92 |
acute respiratory | 92 |
ic values | 91 |
cl pro | 89 |
nmr spectra | 86 |
peptide receptor | 85 |
inhibitory activity | 84 |
hydrogen bonds | 84 |
respiratory syndrome | 80 |
crystal structure | 80 |
nucleic acid | 78 |
mg ml | 78 |
wild hemp | 77 |
column chromatography | 76 |
binding site | 74 |
severe acute | 74 |
immunodeficiency virus | 74 |
human immunodeficiency | 73 |
hydrogen bond | 73 |
dna aptamer | 73 |
patchouli alcohol | 71 |
molecules sha | 70 |
molecules doi | 70 |
doc id | 70 |
hepg cells | 70 |
cord uid | 70 |
gene expression | 70 |
oxidative stress | 68 |
growth factor | 67 |
escherichia coli | 66 |
type ia | 66 |
cfu ml | 66 |
trypsin inhibitor | 62 |
cell line | 62 |
room temperature | 61 |
virus type | 61 |
inhibitory effect | 60 |
based drug | 60 |
herpes simplex | 58 |
coli topoisomerase | 58 |
traditional chinese | 58 |
natural products | 57 |
simplex virus | 57 |
host cell | 56 |
silica gel | 56 |
nucleic acids | 56 |
mass spectrometry | 56 |
authors declare | 55 |
lung cancer | 55 |
clinical trials | 54 |
cov cl | 53 |
protein interactions | 53 |
previously reported | 53 |
cancer therapy | 53 |
active molecules | 53 |
molecular dynamics | 53 |
side effects | 53 |
antibacterial activity | 52 |
respiratory syncytial | 52 |
syncytial virus | 52 |
small molecule | 52 |
chemical shift | 51 |
ns pro | 50 |
main protease | 50 |
viral rna | 50 |
proposed mechanism | 49 |
antimicrobial activity | 49 |
cell viability | 49 |
reverse transcriptase | 49 |
cell proliferation | 49 |
chinese medicine | 49 |
host cells | 49 |
widely used | 48 |
rna aptamers | 48 |
binding affinity | 48 |
ligand binding | 48 |
throughput screening | 48 |
inflammatory cytokines | 47 |
viral infection | 47 |
chemical constituents | 47 |
virus infection | 46 |
aconitine alkaloids | 46 |
rna polymerase | 46 |
deep eutectic | 45 |
docking studies | 45 |
phage display | 45 |
peer review | 45 |
rnai molecules | 44 |
give compound | 44 |
radical scavenging | 44 |
colloidal dispersion | 44 |
molecular mechanisms | 44 |
acid residues | 43 |
immune response | 43 |
positive control | 43 |
general procedure | 42 |
protease inhibitors | 42 |
autophagic cell | 42 |
ic value | 42 |
binding sites | 42 |
staphylococcus aureus | 42 |
fold diluted | 42 |
essential oils | 42 |
ligand interactions | 42 |
antiviral agents | 41 |
present study | 41 |
first step | 41 |
dependent manner | 41 |
topoisomerase iii | 41 |
uv light | 41 |
antiviral activities | 40 |
flash chromatography | 40 |
sodium acetate | 40 |
rna viruses | 39 |
viral infections | 39 |
formic acid | 39 |
desired product | 39 |
viral replication | 39 |
drug delivery | 39 |
biological activities | 39 |
based analytical | 39 |
vitro selection | 39 |
commons attribution | 38 |
small molecules | 38 |
metal nanoparticles | 38 |
bioactive compounds | 38 |
magnetic resonance | 38 |
liquid chromatography | 38 |
creative commons | 38 |
molecular modeling | 38 |
protein interaction | 38 |
antioxidant activity | 37 |
sars coronavirus | 37 |
hydroxyl group | 37 |
results showed | 37 |
detection limit | 37 |
microfluidic paper | 37 |
open access | 37 |
mouse model | 37 |
reverse phase | 37 |
endothelial cells | 36 |
nlrp inflammasome | 36 |
drug development | 36 |
dengue virus | 36 |
phase flash | 36 |
biological activity | 36 |
tumor cells | 36 |
natural compounds | 36 |
terminal domains | 35 |
syndrome coronavirus | 35 |
lung injury | 35 |
yellow solid | 35 |
type ii | 35 |
magnetic field | 35 |
based microfluidic | 35 |
signaling pathway | 35 |
viral envelope | 35 |
herbal medicine | 35 |
ch ch | 35 |
tcm formulas | 35 |
human cathepsin | 35 |
nuclear magnetic | 35 |
ia topoisomerases | 34 |
dendritic cells | 34 |
ray crystallography | 34 |
hydrophobic interactions | 34 |
recent advances | 34 |
type hydrogen | 34 |
access article | 34 |
wide range | 34 |
article distributed | 34 |
prostate cancer | 34 |
nucleophilic attack | 33 |
high affinity | 33 |
cysteine cathepsins | 33 |
anticancer drugs | 33 |
formyl peptides | 33 |
prepared compounds | 33 |
previous studies | 33 |
medicinal plants | 33 |
immune system | 33 |
binding mode | 33 |
analytical devices | 32 |
oxygen species | 32 |
stranded dna | 32 |
virus replication | 32 |
hepatocellular carcinoma | 32 |
antifungal activity | 32 |
data set | 32 |
cell culture | 31 |
immune responses | 31 |
reactive oxygen | 31 |
crystal structures | 31 |
inhibitory effects | 31 |
essential oil | 31 |
protein kinase | 31 |
important role | 31 |
additional water | 31 |
active compounds | 31 |
molarity ratio | 31 |
second step | 31 |
stacking interactions | 31 |
isothermal amplification | 31 |
binding protein | 31 |
nuclear factor | 30 |
free radicals | 30 |
standard deviation | 30 |
md simulation | 30 |
phosphoryl azide | 30 |
chemical shifts | 30 |
mg kg | 30 |
large number | 30 |
fed mice | 30 |
registered cultivars | 30 |
std nmr | 29 |
phytochemical inhibitors | 29 |
side chain | 29 |
stimulated pbmc | 29 |
form hydrogen | 29 |
cell membrane | 29 |
free energy | 29 |
novel coronavirus | 29 |
carbon atoms | 29 |
different concentrations | 29 |
ligand complexes | 29 |
type lectins | 28 |
activity relationship | 28 |
reaction mixture | 28 |
recent years | 28 |
eutectic solvents | 28 |
west nile | 28 |
cell cultures | 28 |
colon cancer | 28 |
oral administration | 28 |
hiv activity | 28 |
dpph radical | 28 |
sirna targeting | 28 |
biological evaluation | 28 |
organic azide | 28 |
following treatment | 28 |
binding pocket | 28 |
commonly used | 28 |
based virtual | 28 |
recent study | 28 |
dmf devices | 28 |
results indicated | 27 |
rna topoisomerase | 27 |
binding lectin | 27 |
antiviral effect | 27 |
inhibitory activities | 27 |
aqueous solution | 27 |
nile virus | 27 |
crude drugs | 27 |
performed using | 27 |
dna cleavage | 27 |
cell adhesion | 27 |
breeding lines | 27 |
peptide receptors | 26 |
human plasma | 26 |
respiratory tract | 26 |
determined using | 26 |
polyphenolic compounds | 26 |
potent anti | 26 |
type i | 26 |
ms ms | 26 |
zikv infection | 26 |
inflammatory diseases | 26 |
binding activity | 25 |
docked pose | 25 |
candida albicans | 25 |
also used | 25 |
cannabis sativa | 25 |
therapeutic potential | 25 |
dna polymerase | 25 |
may also | 25 |
clinical studies | 25 |
microfluidic devices | 25 |
oxidative cross | 25 |
fatty acids | 25 |
scsio xws | 25 |
delivery systems | 25 |
target protein | 25 |
control group | 25 |
nmr experiments | 25 |
airway inflammation | 24 |
inflammatory cytokine | 24 |
therapeutic agents | 24 |
commercially available | 24 |
genetic material | 24 |
binding energies | 24 |
reference compounds | 24 |
factor receptor | 24 |
towards cathepsin | 24 |
type lectin | 24 |
vero cells | 24 |
another study | 24 |
infected cells | 24 |
structural basis | 24 |
pulmonary surfactant | 24 |
best docked | 24 |
cysteine proteases | 24 |
polarization transfer | 24 |
dependent rna | 24 |
life cycle | 24 |
distilled water | 24 |
binding modes | 24 |
antiviral drugs | 24 |
rate constants | 24 |
inflammatory activity | 24 |
compounds showed | 23 |
bovine serum | 23 |
protein structure | 23 |
necrosis factor | 23 |
rat plasma | 23 |
nervous system | 23 |
gold nanoparticle | 23 |
chemical structure | 23 |
forms hydrophobic | 23 |
isoxazolidines cis | 23 |
pseudomonas aeruginosa | 23 |
tcm formula | 23 |
proliferative activity | 23 |
binding proteins | 23 |
potential therapeutic | 23 |
monoclonal antibody | 23 |
decoction pieces | 23 |
independent experiments | 23 |
human diseases | 23 |
pyrazolyl nucleosides | 23 |
antioxidant capacity | 23 |
selected compounds | 23 |
chemical libraries | 23 |
based screening | 23 |
mediated synthesis | 23 |
phenyl ring | 22 |
human cytomegalovirus | 22 |
viral entry | 22 |
hepg cell | 22 |
biscao suspension | 22 |
autodock vina | 22 |
ns protease | 22 |
antiviral drug | 22 |
ia topoisomerase | 22 |
newly synthesized | 22 |
molecular weight | 22 |
docking analysis | 22 |
three independent | 22 |
therapeutic effects | 22 |
standard drug | 22 |
activity relationships | 22 |
induced apoptosis | 22 |
state nmr | 22 |
carbonyl group | 22 |
rna aptamer | 22 |
cysteine protease | 22 |
showed significant | 22 |
recent studies | 22 |
potential inhibitors | 22 |
measured using | 22 |
tumor necrosis | 22 |
cytokine production | 22 |
inhibitor predicted | 22 |
substrate binding | 21 |
envelope protein | 21 |
michael acceptor | 21 |
ppi network | 21 |
human coronavirus | 21 |
mycobacterium tuberculosis | 21 |
drug resistance | 21 |
metal ions | 21 |
metal ion | 21 |
new drugs | 21 |
like protease | 21 |
inhibition activity | 21 |
cancer treatment | 21 |
indole ring | 21 |
free radical | 21 |
isolated yields | 21 |
gastric cancer | 21 |
pulmonary fibrosis | 21 |
cell cycle | 21 |
crude product | 21 |
hydrophobic contacts | 21 |
inflammatory mediators | 20 |
signalling pathway | 20 |
inflammatory effects | 20 |
binding ligands | 20 |
inflammatory response | 20 |
potential targets | 20 |
protein binding | 20 |
interfering rna | 20 |
carboxylic acid | 20 |
induces apoptosis | 20 |
bond formation | 20 |
sb methods | 20 |
phosphoric acid | 20 |
stranded rna | 20 |
ku cells | 20 |
based methods | 20 |
spike glycoprotein | 20 |
active cathepsin | 20 |
ethyl acetate | 20 |
adipose tissue | 20 |
ex vivo | 20 |
cell surface | 20 |
drug candidates | 20 |
induced autophagy | 20 |
natural product | 20 |
critical role | 20 |
virucidal activity | 20 |
cells treated | 20 |
mediated isothermal | 20 |
rnai therapeutics | 20 |
roselle calyces | 20 |
transcription factor | 20 |
energy calculations | 19 |
mouth disease | 19 |
cytotoxic concentration | 19 |
cells via | 19 |
also showed | 19 |
supplementary materials | 19 |
test compounds | 19 |
results obtained | 19 |
machine learning | 19 |
fatty acid | 19 |
mobile phase | 19 |
homology model | 19 |
positively charged | 19 |
zika virus | 19 |
hibiscus sabdariffa | 19 |
coupling reaction | 19 |
gel electrophoresis | 19 |
nucleocapsid protein | 19 |
protein pairs | 19 |
gel column | 19 |
epithelial cells | 19 |
clinical trial | 19 |
enzyme activity | 19 |
ellagic acid | 19 |
tumor cell | 19 |
nitrile compounds | 19 |
antiviral efficacy | 19 |
antiviral action | 19 |
results suggest | 19 |
results revealed | 19 |
small interfering | 19 |
contour map | 19 |
traditional medicine | 18 |
analytical device | 18 |
amide group | 18 |
dipolar cycloaddition | 18 |
central nervous | 18 |
innate immune | 18 |
methyl group | 18 |
counts sec | 18 |
nucleophilic substitution | 18 |
antioxidant properties | 18 |
acid sequences | 18 |
tested compounds | 18 |
ligand interaction | 18 |
molecular targets | 18 |
vascular endothelial | 18 |
plasma membrane | 18 |
azide generation | 18 |
hcv protease | 18 |
cell nmr | 18 |
significant differences | 18 |
topoisomerase activity | 18 |
covalent bond | 18 |
dna topoisomerase | 18 |
molecule inhibitors | 18 |
cellular uptake | 18 |
inflammasome activation | 18 |
molecular similarity | 18 |
target proteins | 18 |
highly potent | 18 |
supplementary tables | 18 |
lamp assay | 18 |
signaling pathways | 18 |
negative bacteria | 18 |
well known | 18 |
complement system | 18 |
western blot | 18 |
protease inhibitor | 18 |
untreated cells | 18 |
inhibition zone | 18 |
nmr data | 18 |
trypsin inhibitors | 18 |
terminal domain | 18 |
physicochemical properties | 18 |
protein expression | 18 |
acetic acid | 18 |
rna molecules | 18 |
fat diet | 18 |
cell entry | 18 |
fpr agonists | 18 |
synthesized compounds | 18 |
disease virus | 18 |
inhibitory concentration | 18 |
viral particles | 18 |
ng ml | 18 |
novo design | 18 |
simultaneous detection | 18 |
crude extract | 17 |
cl protease | 17 |
surface area | 17 |
endoplasmic reticulum | 17 |
known inhibitors | 17 |
enveloped viruses | 17 |
trypsin inhibitory | 17 |
gold bean | 17 |
binding domain | 17 |
approved drugs | 17 |
colorimetric detection | 17 |
statistically significant | 17 |
series i | 17 |
nmr studies | 17 |
activated protein | 17 |
also known | 17 |
cell lung | 17 |
cysteine proteinases | 17 |
supplementary table | 17 |
human respiratory | 17 |
arctium lappa | 17 |
ligand complex | 17 |
epidermal growth | 17 |
pulmonary delivery | 17 |
nmr spectrum | 17 |
bacterial strains | 17 |
phenolic compounds | 17 |
neuraminidase inhibitors | 17 |
model structure | 17 |
using nmr | 17 |
hek cells | 17 |
obtained using | 17 |
amorphous solid | 17 |
formylpeptide receptor | 17 |
strain scsio | 17 |
clinical use | 17 |
first reported | 17 |
indian medicinal | 17 |
listeria monocytogenes | 17 |
cell types | 17 |
deep learning | 17 |
severe covid | 17 |
chinese herbal | 17 |
drug screening | 17 |
computational methods | 17 |
delivery system | 17 |
virus activity | 17 |
mm tris | 17 |
gallic acid | 17 |
serum amyloid | 17 |
molecular mechanism | 17 |
phaseolus vulgaris | 17 |
vaccine development | 16 |
infectious diseases | 16 |
analyzed using | 16 |
potent compounds | 16 |
molecular mass | 16 |
significantly reduced | 16 |
coumaric acid | 16 |
series ii | 16 |
viral vectors | 16 |
phase i | 16 |
vivo studies | 16 |
monoclonal antibodies | 16 |
remained viable | 16 |
vesicular stomatitis | 16 |
flow cytometry | 16 |
cell growth | 16 |
viral genome | 16 |
hydroxyquinoline derivatives | 16 |
industrial hemp | 16 |
serum albumin | 16 |
well plates | 16 |
adhesion molecule | 16 |
human serum | 16 |
receptor binding | 16 |
compounds may | 16 |
response surface | 16 |
relatively low | 16 |
biological functions | 16 |
pulse sequence | 16 |
bruker avance | 16 |
vitro anti | 16 |
united states | 16 |
method using | 16 |
dendritic cell | 16 |
previously described | 16 |
inhibitor complex | 16 |
biologically active | 16 |
anticancer effects | 16 |
white powder | 16 |
drug administration | 16 |
biscao dispersion | 16 |
saturation transfer | 16 |
protein targets | 16 |
carcinoma cells | 16 |
endothelial growth | 16 |
also exhibited | 16 |
caffeic acid | 16 |
inhibition zones | 16 |
bean trypsin | 16 |
cell migration | 16 |
high throughput | 16 |
quantitative structure | 16 |
akt mtor | 15 |
template size | 15 |
cytopathic effect | 15 |
clean water | 15 |
gene silencing | 15 |
directed mutagenesis | 15 |
compounds exhibited | 15 |
tumor growth | 15 |
anomeric proton | 15 |
binding agents | 15 |
study demonstrated | 15 |
research groups | 15 |
human health | 15 |
significant activity | 15 |
resistant strains | 15 |
statistical significance | 15 |
epitope mapping | 15 |
data obtained | 15 |
human embryonic | 15 |
novel anti | 15 |
respiratory diseases | 15 |
avian influenza | 15 |
hydrazone derivatives | 15 |
selective inhibitor | 15 |
building blocks | 15 |
ebola virus | 15 |
electron microscopy | 15 |
new drug | 15 |
protein synthesis | 15 |
serine protease | 15 |
viral protein | 15 |
hemp strain | 15 |
early stages | 15 |
even though | 15 |
great potential | 15 |
available online | 15 |
potent activity | 15 |
structural information | 15 |
clinical effects | 15 |
energy metabolism | 15 |
antiviral properties | 15 |
therapeutic applications | 15 |
performance liquid | 15 |
nmr techniques | 15 |
ml min | 15 |
clinical application | 15 |
dynamics simulations | 15 |
different types | 15 |
site residues | 15 |
relaxation activity | 15 |
electrochemical detection | 15 |
shell powder | 15 |
data sets | 15 |
public health | 15 |
medicinal chemistry | 15 |
mass spectra | 15 |
ch cl | 15 |
structural modification | 15 |
tmprss residues | 15 |
cytotoxic activity | 15 |
structural models | 15 |
respiratory viruses | 15 |
binding residue | 15 |
mrna levels | 15 |
multiplexed detection | 15 |
higher concentration | 14 |
based probes | 14 |
apoptotic cells | 14 |
benzoic acid | 14 |
isoxazolidine ring | 14 |
computer simulation | 14 |
viral proteins | 14 |
three different | 14 |
calcium oxide | 14 |
protein sequence | 14 |
lateral flow | 14 |
core domains | 14 |
target compounds | 14 |
key role | 14 |
brain barrier | 14 |
isoxazolidines trans | 14 |
hemp eo | 14 |
also found | 14 |
pdb code | 14 |
compound library | 14 |
acute lung | 14 |
coupled receptor | 14 |
emodin derivatives | 14 |
human breast | 14 |
stoichiometric waste | 14 |
kg day | 14 |
specific amplification | 14 |
acid sequence | 14 |
transcription factors | 14 |
new series | 14 |
close proximity | 14 |
surface methodology | 14 |
health organization | 14 |
hydrogen atoms | 14 |
antimicrobial peptides | 14 |
induces autophagy | 14 |
structural changes | 14 |
eutectic solvent | 14 |
chemical composition | 14 |
ru iv | 14 |
relaxation edited | 14 |
qsar models | 14 |
potential anti | 14 |
binding free | 14 |
cys residue | 14 |
rna interference | 14 |
obstructive pulmonary | 14 |
rpi data | 14 |
coupling constants | 14 |
isoxazolidine cis | 14 |
selective inhibitors | 14 |
two new | 14 |
nmr spectral | 14 |
growth inhibition | 14 |
side chains | 14 |
structural features | 14 |
world health | 14 |
cationic porphyrins | 14 |
side products | 14 |
target cell | 14 |
rna virus | 14 |
two different | 14 |
radix isatidis | 14 |
chronic obstructive | 14 |
well plate | 14 |
ray diffraction | 14 |
pulmonary disease | 14 |
spike protein | 14 |
supercoiled dna | 14 |
vaccinia virus | 14 |
potential antiviral | 14 |
effective antiviral | 14 |
two compounds | 14 |
chemiluminescence detection | 14 |
induced autophagic | 14 |
peripheral blood | 14 |
protein complexes | 14 |
dmf device | 14 |
si values | 14 |
amino group | 14 |
scoring function | 14 |
eicosapentaenoic acid | 14 |
expression levels | 14 |
multidrug resistance | 14 |
selaginella tamariscina | 14 |
potent inhibitors | 14 |
culture supernatant | 14 |
human neutrophils | 14 |
membrane fusion | 14 |
stomatitis virus | 14 |
normal cells | 14 |
cell lysates | 14 |
electron transfer | 14 |
converting enzyme | 13 |
bioshell calcium | 13 |
systematic review | 13 |
povidone iodine | 13 |
nitrene insertion | 13 |
antibacterial agents | 13 |
conformational changes | 13 |
liquid extraction | 13 |
much lower | 13 |
potential target | 13 |
docked protein | 13 |
protein data | 13 |
glycyrrhiza uralensis | 13 |
negatively charged | 13 |
pancreatic cancer | 13 |
protein complex | 13 |
structural proteins | 13 |
respiratory infections | 13 |
based catalyst | 13 |
small cell | 13 |
biological properties | 13 |
synthetic routes | 13 |
novo drug | 13 |
der waals | 13 |
burdock root | 13 |
signal intensity | 13 |
reaction mixtures | 13 |
compounds containing | 13 |
display technology | 13 |
fpr antagonists | 13 |
human cancer | 13 |
van der | 13 |
human cervical | 13 |
statistical analysis | 13 |
functional groups | 13 |
hemp cultivars | 13 |
factor xa | 13 |
colorless amorphous | 13 |
antiviral effects | 13 |
hcv ns | 13 |
based inhibitors | 13 |
pharmacological studies | 13 |
reduced pressure | 13 |
anticancer activity | 13 |
magnetic fields | 13 |
high concentrations | 13 |
signal amplification | 13 |
particle size | 13 |
cervical cancer | 13 |
data bank | 13 |
therapeutic targets | 13 |
ec values | 13 |
salt elimination | 13 |
synthesis via | 13 |
antiproliferative activity | 13 |
hydroxyl groups | 13 |
cycle arrest | 13 |
wide variety | 13 |
new therapeutic | 13 |
ki values | 13 |
covalent modification | 13 |
oxygen atom | 13 |
matrix effect | 13 |
ephedra sinica | 13 |
using different | 13 |
colorectal cancer | 13 |
seven analytes | 13 |
peptide sequence | 13 |
shape similarity | 13 |
worth noting | 13 |
blot analysis | 13 |
developed using | 13 |
phylogenetic analysis | 13 |
toward cathepsin | 13 |
taken together | 13 |
sirna delivery | 13 |
derivatives synthesis | 13 |
drug molecules | 13 |
synthesized using | 13 |
ligand docking | 13 |
cimicifuga simplex | 13 |
plaque formation | 13 |
first time | 13 |
free ligand | 13 |
anticancer drug | 13 |
molecular recognition | 13 |
mass production | 13 |
rat model | 13 |
sialic acid | 13 |
reversible exchange | 12 |
mannose binding | 12 |
different stages | 12 |
new antiviral | 12 |
gp binding | 12 |
carcinogenic cells | 12 |
ple band | 12 |
rsv infection | 12 |
selectivity index | 12 |
tuberculosis topoisomerase | 12 |
aerial parts | 12 |
scanning electron | 12 |
animal models | 12 |
pharmacological effects | 12 |
carbohydrate recognition | 12 |
binding specificity | 12 |
transfer difference | 12 |
protective effect | 12 |
cs co | 12 |
human formyl | 12 |
chemical structures | 12 |
gated channel | 12 |
ray crystal | 12 |
dna binding | 12 |
new derivatives | 12 |
nucleoside analogues | 12 |
scallop shell | 12 |
reaction mechanism | 12 |
various concentrations | 12 |
based assays | 12 |
type diabetes | 12 |
intramolecular cyclization | 12 |
experimental data | 12 |
cinnamomum cassia | 12 |
enhanced extraction | 12 |
antitumor activity | 12 |
stacking interaction | 12 |
force field | 12 |
valproic acid | 12 |
significantly different | 12 |
nanomolar range | 12 |
overhauser effect | 12 |
new compounds | 12 |
target products | 12 |
molecular target | 12 |
tandem mass | 12 |
natural deep | 12 |
fresh medium | 12 |
diffusion nmr | 12 |
showed good | 12 |
rational design | 12 |
much higher | 12 |
ch op | 12 |
crude products | 12 |
diabetes mellitus | 12 |
free binding | 12 |
negative control | 12 |
dipeptidyl peptidase | 12 |
effective concentration | 12 |
homology modeling | 12 |
active compound | 12 |
highly pathogenic | 12 |
fold selectivity | 12 |
whole blood | 12 |
sulfonamide complexes | 12 |
caryophyllene oxide | 12 |
primary amines | 12 |
values ranging | 12 |
naturally occurring | 12 |
saposhnikoviae radix | 12 |
mtor signaling | 12 |
natural sources | 12 |
solid state | 12 |
cells using | 12 |
oxidative damage | 12 |
also reported | 12 |
atopic dermatitis | 12 |
citric acid | 12 |
vivo selection | 12 |
lipid peroxidation | 12 |
derived growth | 12 |
chemotherapeutic agents | 12 |
qbsc complexes | 12 |
plant lectins | 12 |
epa plus | 12 |
astragali radix | 12 |
derived kernel | 12 |
active components | 12 |
culture medium | 12 |
low concentration | 12 |
correlation peaks | 12 |
rpirls method | 12 |
simplex wormsk | 12 |
cardiovascular diseases | 12 |
prime site | 12 |
inflammatory effect | 12 |
group displayed | 12 |
hydrogen peroxide | 12 |
minimum inhibitory | 12 |
authors reported | 12 |
calibration curve | 12 |
last years | 12 |
drug targets | 12 |
cimicifuga species | 12 |
gene products | 11 |
edited nmr | 11 |
protein structures | 11 |
lead compounds | 11 |
coreldraw software | 11 |
water molecule | 11 |
acid group | 11 |
training set | 11 |
usa hemp | 11 |
hybrid quinoline | 11 |
cd receptor | 11 |
antifungal activities | 11 |
bioactive component | 11 |
latent period | 11 |
active sites | 11 |
pharmacological properties | 11 |
ir spectra | 11 |
developed compound | 11 |
md simulations | 11 |
membrane proteins | 11 |
docking scores | 11 |
derived components | 11 |
cancer progression | 11 |
infected patients | 11 |
solid ratio | 11 |
coli dna | 11 |
envelope glycoprotein | 11 |
corporation id | 11 |
virus infections | 11 |
singlet oxygen | 11 |
based microfluidics | 11 |
pharmacokinetic study | 11 |
chemical biology | 11 |
reduction assay | 11 |
powerful tool | 11 |
influenza viruses | 11 |
coronavirus disease | 11 |
clinical applications | 11 |
targeted drug | 11 |
aspergillus sp | 11 |
way anova | 11 |
heated scallop | 11 |
virus entry | 11 |
targeted delivery | 11 |
nitric oxide | 11 |
cancer therapies | 11 |
von willebrand | 11 |
closely related | 11 |
hit compounds | 11 |
catalytic cysteine | 11 |
inhibitory potency | 11 |
internal standard | 11 |
pharmacokinetic parameters | 11 |
fpr agonist | 11 |
distress syndrome | 11 |
mammalian cells | 11 |
wound healing | 11 |
spectral data | 11 |
dose response | 11 |
potential anticancer | 11 |
functional group | 11 |
different cell | 11 |
steric hindrance | 11 |
human fpr | 11 |
irreversible inhibitors | 11 |
target cells | 11 |
assisted extraction | 11 |
transforming growth | 11 |
fetal bovine | 11 |
fold higher | 11 |
cell receptor | 11 |
often used | 11 |
based device | 11 |
ucsf chimera | 11 |
cell fusion | 11 |
high concentration | 11 |
sequence identity | 11 |
derived nitrones | 11 |
plus ht | 11 |
results indicate | 11 |
coxsackie virus | 11 |
bovine viral | 11 |
micromolar range | 11 |
upper respiratory | 11 |
docking poses | 11 |
sar analysis | 11 |
low detection | 11 |
rate constant | 11 |
mononuclear cells | 11 |
halogen atom | 11 |
tyrosine kinase | 11 |
showed ic | 11 |
copper catalyst | 11 |
docking simulations | 11 |
template surface | 11 |
received epa | 11 |
dialkyl phosphite | 11 |
corel corporation | 11 |
catalyzed oxidative | 11 |
synergistic effect | 11 |
catalytic residues | 11 |
four glucosinolates | 11 |
high temperature | 11 |
selectivity towards | 11 |
hiv vaccine | 11 |
lung inflammation | 11 |
ovarian cancer | 11 |
galanthus nivalis | 11 |
nuclear overhauser | 11 |
inflammatory responses | 11 |
positive bacteria | 11 |
induced polarization | 11 |
nmr methods | 11 |
medium containing | 11 |
benzoxazine ring | 11 |
touchdown lamp | 11 |
respiratory distress | 11 |
may play | 11 |
coworkers prepared | 11 |
viral surface | 11 |
chronic inflammation | 11 |
allergic asthma | 11 |
normal human | 11 |
inflammatory activities | 11 |
microbicidal activity | 11 |
drug interactions | 11 |
mrna expression | 11 |
cell apoptosis | 11 |
neutralizing antibodies | 11 |
innate immunity | 11 |
phase ii | 11 |
atractylenolide ii | 11 |
specific plant | 11 |
flow rate | 11 |
si value | 11 |
new class | 11 |
scrambled peptide | 11 |
docking study | 11 |
antimicrobial activities | 11 |
conformational change | 11 |
reduce virus | 10 |
seven compounds | 10 |
ganoderma lucidum | 10 |
fluid flow | 10 |
conformational analysis | 10 |
highly selective | 10 |
pl spectra | 10 |
sindbis virus | 10 |
chemically modified | 10 |
cinnamic acid | 10 |
serially diluted | 10 |
rna binding | 10 |
diseases including | 10 |
estimated binding | 10 |
herpes virus | 10 |
neurodegenerative disease | 10 |
hydrogen atom | 10 |
willebrand factor | 10 |
spectrum antiviral | 10 |
todd reaction | 10 |
fever virus | 10 |
surfactant protein | 10 |
compound also | 10 |
beneficial effects | 10 |
explored using | 10 |
aryl amines | 10 |
neural network | 10 |
drug binding | 10 |
inflammatory cells | 10 |
preparative hplc | 10 |
isolated yield | 10 |
molecular interactions | 10 |
sars cov | 10 |
positive selection | 10 |
enveloped virus | 10 |
gene delivery | 10 |
channel type | 10 |
enhancement factor | 10 |
synthetic route | 10 |
dried powder | 10 |
potential drugs | 10 |
peripheral substituents | 10 |
hiv agents | 10 |
different human | 10 |
covalent interactions | 10 |
human gastric | 10 |
gp protein | 10 |
various diseases | 10 |
forming units | 10 |
interaction fingerprint | 10 |
substituted aryl | 10 |
substrate specificity | 10 |
dna template | 10 |
small amount | 10 |
low cost | 10 |
better understanding | 10 |
dependent dna | 10 |
normal cell | 10 |
activity using | 10 |
big data | 10 |
affinity binding | 10 |
mm edta | 10 |
chain reaction | 10 |
vein endothelial | 10 |
desired products | 10 |
target product | 10 |
docking using | 10 |
previous reports | 10 |
human umbilical | 10 |
also observed | 10 |
semen ziziphi | 10 |
th cells | 10 |
obtained results | 10 |
docking methods | 10 |
cancer drug | 10 |
electrophilic warhead | 10 |
phase iii | 10 |
sb techniques | 10 |
organic halides | 10 |
signal transduction | 10 |
physical properties | 10 |
covalent complex | 10 |
cov infection | 10 |
melting points | 10 |
aliphatic amines | 10 |
authors also | 10 |
novel therapeutic | 10 |
sars cl | 10 |
calcium mobilization | 10 |
protective effects | 10 |
acid groups | 10 |
structure determination | 10 |
immune cells | 10 |
using autodock | 10 |
inhibitory properties | 10 |
radix salviae | 10 |
comprehensive review | 10 |
using cell | 10 |
pharmacologic activities | 10 |
several studies | 10 |
antioxidant potential | 10 |
specific binding | 10 |
sprayed onto | 10 |
pg ml | 10 |
edge type | 10 |
sodium voltage | 10 |
atractylodis rhizoma | 10 |
significant inhibition | 10 |
resonance spectroscopy | 10 |
sugar moieties | 10 |
crucial role | 10 |
using mm | 10 |
concentration required | 10 |
data presented | 10 |
vitro evaluation | 10 |
least potent | 10 |
significant difference | 10 |
quantitative analysis | 10 |
less active | 10 |
viable following | 10 |
polymerase chain | 10 |
described previously | 10 |
strictly conserved | 10 |
quality control | 10 |
glycoprotein gp | 10 |
viral attachment | 10 |
interaction networks | 10 |
myd dimerisation | 10 |
least squares | 10 |
derivatives containing | 10 |
isomeric pyrazolyl | 10 |
peptidyl aryl | 10 |
diagnostic tools | 10 |
bacterial topoisomerase | 10 |
based probe | 10 |
indole moiety | 10 |
specific activity | 10 |
plasmodium falciparum | 10 |
viral diseases | 10 |
virus control | 10 |
ascorbic acid | 10 |
lipid metabolism | 10 |
inflammatory properties | 10 |
antiviral compounds | 10 |
studies demonstrated | 10 |
specific aptamers | 10 |
gambogic acid | 10 |
organic dye | 10 |
peptide fraction | 10 |
aryl group | 10 |
salviae miltiorrhizae | 10 |
screen printing | 10 |
chemical space | 10 |
transition metal | 10 |
reference drug | 10 |
umbilical vein | 10 |
isolated product | 10 |
antioxidant effect | 10 |
various types | 10 |
canine coronavirus | 10 |
promega co | 10 |
maximal inhibitory | 10 |
ns md | 10 |
exhibited potent | 10 |
pdb format | 10 |
lactams trans | 10 |
na hpo | 10 |
ziziphi spinosae | 10 |
coated silver | 10 |
rheumatoid arthritis | 10 |
hong kong | 10 |
molecules may | 10 |
cells well | 10 |
potent inhibitor | 10 |
pbsa method | 10 |
selection strategies | 10 |
blood mononuclear | 10 |
herbal medicines | 10 |
enzyme inhibitors | 10 |
choline chloride | 10 |
highest binding | 9 |
ms method | 9 |
inactivation kinetics | 9 |
detection sensitivity | 9 |
cell membranes | 9 |
commercial production | 9 |
resulting mixture | 9 |
locked nucleic | 9 |
increased expression | 9 |
substituted derivatives | 9 |
hydrogen bonding | 9 |
substitution pattern | 9 |
acid derivatives | 9 |
essential proteins | 9 |
wood pieces | 9 |
microbicidal activities | 9 |
allowed us | 9 |
compound concentration | 9 |
stationary level | 9 |
membrane protein | 9 |
compounds using | 9 |
potassium carbonate | 9 |
fatty acyl | 9 |
alkaline phosphatase | 9 |
aryl ring | 9 |
induced cell | 9 |
noldeae constituents | 9 |
root mean | 9 |
heart disease | 9 |
broad singlet | 9 |
hela cells | 9 |
common ancestor | 9 |
transcriptase inhibitory | 9 |
reducing agent | 9 |
isoxazolidine analogues | 9 |
infected mice | 9 |
investigated using | 9 |
two classes | 9 |
total anthocyanin | 9 |
protein sequences | 9 |
showed higher | 9 |
pharmacokinetic studies | 9 |
high sensitivity | 9 |
peptide ligands | 9 |
gold glyconanoparticles | 9 |
tumor activity | 9 |
tract infections | 9 |
matrix metalloproteinase | 9 |
elemental mapping | 9 |
aryl vinylsulfonate | 9 |
autophagy via | 9 |
hepatoma cells | 9 |
blood cells | 9 |
tmprss model | 9 |
enzyme active | 9 |
progeny yield | 9 |
whose binding | 9 |
flame retardants | 9 |
like particles | 9 |
parameters evaluated | 9 |
structural analysis | 9 |
anthocyanin degradation | 9 |
low micromolar | 9 |
allergic rhinitis | 9 |
genome sequence | 9 |
low sensitivity | 9 |
urtica dioica | 9 |
human lung | 9 |
antiviral therapy | 9 |
graphpad prism | 9 |
authors used | 9 |
host immune | 9 |
pose prediction | 9 |
pulse sequences | 9 |
adhesion molecules | 9 |
major constituents | 9 |
exhibited significant | 9 |
compound libraries | 9 |
nelumbo nucifera | 9 |
hcv activities | 9 |
marine sponge | 9 |
microfluidic device | 9 |
human liver | 9 |
combined use | 9 |
benzimidazole derivatives | 9 |
identify potential | 9 |
simple method | 9 |
therapeutic effect | 9 |
plasma sample | 9 |
novel series | 9 |
optical density | 9 |
functionalized gold | 9 |
au nanoparticles | 9 |
ac interacted | 9 |
contaminated wood | 9 |
rapid development | 9 |
virus ns | 9 |
via autophagy | 9 |
pld values | 9 |
results suggested | 9 |
living cells | 9 |
activity compared | 9 |
direct interaction | 9 |
simultaneous determination | 9 |
curves correspond | 9 |
therapeutic target | 9 |
phenolic group | 9 |
alveolar macrophages | 9 |
aromatic proton | 9 |
potential drug | 9 |
derivatives exhibited | 9 |
lamp reactions | 9 |
extracellular matrix | 9 |
activity evaluation | 9 |
co incubator | 9 |
false positives | 9 |
mimotope sequence | 9 |
layer chromatography | 9 |
results also | 9 |
cell invasion | 9 |
time points | 9 |
cysteine proteinase | 9 |
early stage | 9 |
may contribute | 9 |
myeloid leukemia | 9 |
catalytic residue | 9 |
two novel | 9 |
embryonic kidney | 9 |
authors suggested | 9 |
photodynamic inactivation | 9 |
virus titers | 9 |
recently described | 9 |
chemical properties | 9 |
two distinct | 9 |
also evaluated | 9 |
accession number | 9 |
three compounds | 9 |
pathogenic bacteria | 9 |
good agreement | 9 |
crystallographic data | 9 |
reaction conditions | 9 |
least two | 9 |
virus particles | 9 |
complex stabilization | 9 |
method based | 9 |
protoporphyrin ix | 9 |
anticancer agents | 9 |
tanshinone iia | 9 |
peptide aldehyde | 9 |
two main | 9 |
hibiscus noldeae | 9 |
high potential | 9 |
phosphoramidate synthesis | 9 |
cell control | 9 |
whole cells | 9 |
high viscosity | 9 |
blank plasma | 9 |
cartoon representation | 9 |
mic values | 9 |
animal lectins | 9 |
reverse transcription | 9 |
future studies | 9 |
proposed method | 9 |
control signal | 9 |
containing mm | 9 |
new insights | 9 |
elisa kit | 9 |
significant reduction | 9 |
anticancer activities | 9 |
direct precipitation | 9 |
total antioxidant | 9 |
soybean trypsin | 9 |
based molecular | 9 |
circular dichroism | 9 |
low toxicity | 9 |
studies reported | 9 |
unrelated peptides | 9 |
japanese encephalitis | 9 |
results show | 9 |
molecular dynamic | 9 |
sugar moiety | 9 |
derived fungus | 9 |
topoisomerase activities | 9 |
apoptotic cell | 9 |
synthetic strategy | 9 |
eo constituents | 9 |
mm nacl | 9 |
three times | 9 |
washed twice | 9 |
process using | 9 |
study showed | 9 |
acute myeloid | 9 |
rna genome | 9 |
phosphoryl amino | 9 |
similarity measurements | 9 |
catalytic cycle | 9 |
gene specific | 9 |
noe spectra | 9 |
using various | 9 |
antimicrobial agents | 9 |
leaving group | 9 |
mean square | 9 |
polyunsaturated fatty | 9 |
usa strain | 9 |
related tups | 9 |
antigen delivery | 9 |
evaluated using | 9 |
novel class | 9 |
growth factors | 9 |
synergistic effects | 9 |
paramagnetic center | 8 |
fmdv infection | 8 |
spin diffusion | 8 |
cytokine secretion | 8 |
spontaneous hemp | 8 |
coagulation factor | 8 |
mycophenolic acid | 8 |
active ingredient | 8 |
induce apoptosis | 8 |
energy minimization | 8 |
antioxidant activities | 8 |
effectively inhibit | 8 |
detected cathepsin | 8 |
weak antioxidants | 8 |
molar ratio | 8 |
pharmacophore model | 8 |
plasmon resonance | 8 |
directly related | 8 |
mice fed | 8 |
macular degeneration | 8 |
glycosylation sites | 8 |
isolated compounds | 8 |
lactam ring | 8 |
frequently used | 8 |
three main | 8 |
potassium channels | 8 |
takes place | 8 |
pe values | 8 |
computational prediction | 8 |
addition assay | 8 |
raman scattering | 8 |
human tissues | 8 |
major active | 8 |
ir bands | 8 |
terminal core | 8 |
animal species | 8 |
associated coronavirus | 8 |
goitrin content | 8 |
viral gp | 8 |
false positive | 8 |
synthetic peptide | 8 |
different time | 8 |
significantly lower | 8 |
inhibition profile | 8 |
active ingredients | 8 |
also synthesized | 8 |
viral glycoproteins | 8 |
target analytes | 8 |
dimensional structure | 8 |
within min | 8 |
magnesium ions | 8 |
binding affinities | 8 |
nmr experiment | 8 |
antibody response | 8 |
ml solvent | 8 |
per sample | 8 |
neurodegenerative diseases | 8 |
reference compound | 8 |
cancer biomarkers | 8 |
secondary metabolites | 8 |
ace receptor | 8 |
hypoiodous acid | 8 |
aqueous phase | 8 |
target molecules | 8 |
search space | 8 |
hiv infection | 8 |
interesting study | 8 |
human coronaviruses | 8 |
selection process | 8 |
ch cn | 8 |
based studies | 8 |
skin cancer | 8 |
thermal degradation | 8 |
diseases caused | 8 |
surgical masks | 8 |
vitro inhibition | 8 |
antisense oligonucleotides | 8 |
metal catalysts | 8 |
polyacrylamide gel | 8 |
least three | 8 |
less toxic | 8 |
potential role | 8 |
recognition domain | 8 |
diffusion time | 8 |
coli atcc | 8 |
langerhans cells | 8 |
lymph nodes | 8 |
pyrazole derivatives | 8 |
feline calicivirus | 8 |
negatively supercoiled | 8 |
inhibit viral | 8 |
ammonium acetate | 8 |
linked immunosorbent | 8 |
third intracellular | 8 |
lead compound | 8 |
negative selection | 8 |
cathepsin inhibitor | 8 |
autophagy induction | 8 |
mg gae | 8 |
current study | 8 |
three new | 8 |
methyl acrylate | 8 |
biological testing | 8 |
quinoline derivatives | 8 |
one compound | 8 |
grand challenge | 8 |
also tested | 8 |
main chain | 8 |
artificial intelligence | 8 |
significant increase | 8 |
cervix carcinoma | 8 |
inflammatory process | 8 |
relaxation times | 8 |
infected wounds | 8 |
bond lengths | 8 |
east respiratory | 8 |
nitrogen atom | 8 |
study revealed | 8 |
phytochemical compounds | 8 |
chinese medicinal | 8 |
laser desorption | 8 |
tris buffer | 8 |
major components | 8 |
purified trypsin | 8 |
conducted using | 8 |
flight mass | 8 |
mts assay | 8 |
sephadex lh | 8 |
based digital | 8 |
human tumor | 8 |
multiple myeloma | 8 |
radix ginseng | 8 |
also forms | 8 |
successfully used | 8 |
contaminated suspension | 8 |
based devices | 8 |
ros rns | 8 |
docked binding | 8 |
dna topoisomerases | 8 |
similar inhibitory | 8 |
green tea | 8 |
enzymes involved | 8 |
difference spectrum | 8 |
fold magnification | 8 |
retention time | 8 |
catalytic activity | 8 |
inhibition rate | 8 |
antiplasmodial activity | 8 |
cell number | 8 |
peptide libraries | 8 |
apoptosis via | 8 |
gradient pulse | 8 |
rna duplexes | 8 |
highest concentration | 8 |
biscao particles | 8 |
zoster virus | 8 |
human colon | 8 |
positive results | 8 |
masked palm | 8 |
catalytic cys | 8 |
radix polygalae | 8 |
selectivity profile | 8 |
chemical modification | 8 |
cancer activity | 8 |
sulfonamide ligand | 8 |
systemic lupus | 8 |
rpirls classifier | 8 |
compound inhibited | 8 |
small organic | 8 |
acid esters | 8 |
sequence similarity | 8 |
silver nanoparticle | 8 |
second dimension | 8 |
following equation | 8 |
cancer via | 8 |
nitrile group | 8 |
smooth muscle | 8 |
gel filtration | 8 |
multiple binding | 8 |
mmt assay | 8 |
cd chromatograms | 8 |
cell activation | 8 |
selectivity toward | 8 |
interactions within | 8 |
novel drug | 8 |
drying biscao | 8 |
clinical practice | 8 |
filter paper | 8 |
infections caused | 8 |
wild hemps | 8 |
host defense | 8 |
high selectivity | 8 |
structural elucidation | 8 |
eo profile | 8 |
plasmid dna | 8 |
peptide sequences | 8 |
concentration range | 8 |
target identification | 8 |
liver injury | 8 |
relative configurations | 8 |
take place | 8 |
pharmaceutical compounds | 8 |
hypochlorous acid | 8 |
antiseptics disinfectants | 8 |
coumarin derivatives | 8 |
infectious disease | 8 |
petri dishes | 8 |
quercetin derivatives | 8 |
values increased | 8 |
pharmacological activities | 8 |
product inhibitors | 8 |
human viruses | 8 |
next step | 8 |
phytochemicals whose | 8 |
scavenging values | 8 |
immunomodulatory effects | 8 |
competitive binding | 8 |
black curve | 8 |
common cold | 8 |
water molecules | 8 |
broad range | 8 |
epa ht | 8 |
conformational strain | 8 |
coronavirus nucleocapsid | 8 |
akt signaling | 8 |
significantly increased | 8 |
qsar model | 8 |
devices using | 8 |
amine complex | 8 |
antibacterial properties | 8 |
potential use | 8 |
ion channel | 8 |
photodynamic therapy | 8 |
human cells | 8 |
screened ligands | 8 |
two steps | 8 |
drug interaction | 8 |
butyl group | 8 |
data base | 8 |
protein gp | 8 |
phosphoric ester | 8 |
first stage | 8 |
ge healthcare | 8 |
dielectric layer | 8 |
influenza neuraminidase | 8 |
biological samples | 8 |
also investigated | 8 |
ns using | 8 |
substituted benzyl | 8 |
ester group | 8 |
based therapeutics | 8 |
sample preparation | 8 |
pharmacokinetic properties | 8 |
years ago | 8 |
zikv rna | 8 |
human body | 8 |
specific inhibition | 8 |
learning methods | 8 |
afford compound | 8 |
flexible docking | 8 |
analysis revealed | 8 |
molecular formula | 8 |
microfluidic chip | 8 |
heat shock | 8 |
nsulfonamide bonds | 8 |
treatment group | 8 |
vivo imaging | 8 |
yellow fever | 8 |
acid synthase | 8 |
centrality measurements | 8 |
based assay | 8 |
calculated using | 8 |
supplementary material | 8 |
human neutrophil | 8 |
five fractions | 8 |
burdock roots | 8 |
surface plasmon | 8 |
red blood | 8 |
lupus erythematosus | 8 |
bioinformatics tools | 8 |
vaccine delivery | 8 |
drug research | 8 |
therapeutic efficacy | 8 |
st molecule | 8 |
active component | 8 |
host factors | 8 |
entry inhibitor | 8 |
adverse effects | 8 |
aromatic interactions | 8 |
digital microfluidic | 8 |
author contributions | 8 |
top inhibitors | 8 |
rnai therapy | 8 |
electrochemical sensors | 8 |
allergic inflammation | 8 |
wormsk studies | 8 |
controlled trial | 8 |
ht supplementation | 8 |
pot synthesis | 8 |
comparative analysis | 8 |
dependent kinase | 8 |
various cancer | 8 |
raman spectrum | 8 |
lamp reaction | 8 |
wave numbers | 8 |
undergoes hydrolysis | 8 |
multiscale models | 8 |
poor solubility | 8 |
largely stable | 8 |
helicobacter pylori | 8 |
middle east | 8 |
prompted us | 8 |
smegmatis topoisomerase | 8 |
rna levels | 8 |
different approaches | 8 |
assisted synthesis | 8 |
ml penicillin | 7 |
aromatic rings | 7 |
inhibitory action | 7 |
human topoisomerase | 7 |
virus neuraminidase | 7 |
superoxide generation | 7 |
potential molecular | 7 |
acid aptamers | 7 |
like compounds | 7 |
high levels | 7 |
ca ions | 7 |
virus rna | 7 |
virus inactivation | 7 |
study reported | 7 |
ester derivatives | 7 |
terminal kinase | 7 |
commercial drugs | 7 |
plasma concentration | 7 |
pubchem identifier | 7 |
chemical databases | 7 |
th cytokines | 7 |
real time | 7 |
vacuum evaporation | 7 |
ht co | 7 |
plants used | 7 |
nude mice | 7 |
mass spectrometer | 7 |
alkyl chains | 7 |
computational drug | 7 |
last decade | 7 |
drug action | 7 |
platelet aggregation | 7 |
corona virus | 7 |
photochemical process | 7 |
phenyl group | 7 |
thymidine kinase | 7 |
based approaches | 7 |
halogen bonds | 7 |
alarm nmr | 7 |
final concentration | 7 |
nitrogen atoms | 7 |
free protein | 7 |
brown solid | 7 |
shock protein | 7 |
probably due | 7 |
condensation reaction | 7 |
directed ligands | 7 |
major component | 7 |
conserved region | 7 |
labeled dna | 7 |
human dermal | 7 |
isotopically labeled | 7 |
timosaponin aiii | 7 |
action mechanisms | 7 |
visual detection | 7 |
qsc compounds | 7 |
new method | 7 |
using high | 7 |
peptide agonist | 7 |
electrophoretic separation | 7 |
raman spectra | 7 |
digital microfluidics | 7 |
random peptide | 7 |
aureus atcc | 7 |
mice showed | 7 |
novel drugs | 7 |
random forest | 7 |
may affect | 7 |
molecular modelling | 7 |
protein target | 7 |
different cancer | 7 |
inhibit hiv | 7 |
previous study | 7 |
based nmr | 7 |
virtual databases | 7 |
activity towards | 7 |
cimicifuga foetida | 7 |
coreceptor binding | 7 |
scavenging activity | 7 |
mechanistic process | 7 |
identified phytochemical | 7 |
diethyl hydrogen | 7 |
vibrational mode | 7 |
multiple analytes | 7 |
akt pathway | 7 |
analysis showed | 7 |
method used | 7 |
sensitive nuclei | 7 |
step mechanistic | 7 |
bound ligands | 7 |
clinical study | 7 |
cervical carcinoma | 7 |
previous report | 7 |
traditionally used | 7 |
reverse gyrase | 7 |
cardiovascular disease | 7 |
also shown | 7 |
lower limit | 7 |
target derivative | 7 |
apoptosis induction | 7 |
binding profiles | 7 |
interactions using | 7 |
human hepatoma | 7 |
terminal residue | 7 |
aqueous extracts | 7 |
isatin derivatives | 7 |
hydrophobic sub | 7 |
pro complexed | 7 |
biotinylated aziridine | 7 |
induced liver | 7 |
late stage | 7 |
chemical modifications | 7 |
efficient method | 7 |
dry powder | 7 |
toro virus | 7 |
induced acute | 7 |
potent antiviral | 7 |
ii clinical | 7 |
nt sequence | 7 |
clinical development | 7 |
allergic airway | 7 |
strand rna | 7 |
five times | 7 |
million people | 7 |
genetic algorithm | 7 |
commonly found | 7 |
signalling pathways | 7 |
crude reaction | 7 |
aziridine ring | 7 |
intracellular loop | 7 |
biology tools | 7 |
phenolic hydroxyl | 7 |
excited state | 7 |
pulmonary drug | 7 |
peptide agonists | 7 |
pattern recognition | 7 |
bw gain | 7 |
oscillatoria agardhii | 7 |
silico screening | 7 |
buffer solution | 7 |
cnestis ferruginea | 7 |
dock study | 7 |
aromatic ring | 7 |
free radic | 7 |
triethyl phosphite | 7 |
affinity selection | 7 |
sulfur atom | 7 |
visible light | 7 |
ca cam | 7 |
iodide ion | 7 |
developing new | 7 |
secondary amines | 7 |
containing amino | 7 |
japanese herbal | 7 |
per well | 7 |
comparable results | 7 |
carbohydrate structures | 7 |
antimycobacterial activity | 7 |
present review | 7 |
gastrointestinal tract | 7 |
mmol ise | 7 |
top three | 7 |
thiol group | 7 |
comparison test | 7 |
new approach | 7 |
transition state | 7 |
activity toward | 7 |
two major | 7 |
radical initiator | 7 |
acne skin | 7 |
fbdd approach | 7 |
new coronavirus | 7 |
scheme route | 7 |
drug target | 7 |
site substituent | 7 |
newly developed | 7 |
sequence alignment | 7 |
virus binding | 7 |
fluorescence microscope | 7 |
envelope proteins | 7 |
treatment stage | 7 |
adenocarcinoma cells | 7 |
pentaherb formula | 7 |
ir spectrum | 7 |
mixture containing | 7 |
culture plate | 7 |
paeonia lactiflora | 7 |
viral strains | 7 |
rna template | 7 |
spectroscopic techniques | 7 |
site tyrosine | 7 |
inhibitory efficacy | 7 |
complex formed | 7 |
thorough sar | 7 |
data fusion | 7 |
blood vessels | 7 |
hippeastrum hybrid | 7 |
insulin resistance | 7 |
surgical mask | 7 |
space group | 7 |
worth mentioning | 7 |
derivatives showed | 7 |
effective way | 7 |
dependent pathway | 7 |
envelope glycoproteins | 7 |
modified atherton | 7 |
silver ions | 7 |
bacterial cell | 7 |
dihydrofolate reductase | 7 |
longitudinal relaxation | 7 |
myrianthus holstii | 7 |
gas chromatography | 7 |
fpr fpr | 7 |
table summarizes | 7 |
cardiotoxicity induced | 7 |
strain eo | 7 |
displayed stronger | 7 |
acnes pcm | 7 |
triplet state | 7 |
specific cell | 7 |
glycan cryptic | 7 |
two regioisomers | 7 |
viral dna | 7 |
western blotting | 7 |
triazole derivatives | 7 |
computational tools | 7 |
external complex | 7 |
possible target | 7 |
cell type | 7 |
based delivery | 7 |
cell survival | 7 |
method called | 7 |
neural networks | 7 |
shift changes | 7 |
fabrication method | 7 |
energy transfer | 7 |
electrostatic contour | 7 |
cell monolayers | 7 |
developed probe | 7 |
final product | 7 |
strand passage | 7 |
sigma aldrich | 7 |
also called | 7 |
hfd feeding | 7 |
aromatic aldehydes | 7 |
least one | 7 |
gold particles | 7 |
endosomal escape | 7 |
undergoes nucleophilic | 7 |
th th | 7 |
water bath | 7 |
cancer activities | 7 |
programmed cell | 7 |
arginine residue | 7 |
hq derivatives | 7 |
showed activity | 7 |
time pcr | 7 |
tfa salts | 7 |
intercellular adhesion | 7 |
fluid manipulation | 7 |
ec value | 7 |
even better | 7 |
inhibition assay | 7 |
formylated peptides | 7 |
electron microscope | 7 |
excitation wavelength | 7 |
receptor antagonist | 7 |
like receptors | 7 |
colorimetric assay | 7 |
liver cancer | 7 |
cancer development | 7 |
susceptibility factors | 7 |
rna replication | 7 |
good yield | 7 |
three types | 7 |
elemental analysis | 7 |
well established | 7 |
chinese medicines | 7 |
molecular basis | 7 |
multiplexed analysis | 7 |
irreversible inhibitor | 7 |
prepared using | 7 |
urease inhibitors | 7 |
active nuclei | 7 |
suckling mice | 7 |
catalyzed synthesis | 7 |
attribution license | 7 |
different natural | 7 |
glioma cells | 7 |
sodium dialkyl | 7 |
human fibroblasts | 7 |
three novel | 7 |
cancer treatments | 7 |
inhibit influenza | 7 |
different chemical | 7 |
based diagnostic | 7 |
antagonistic activity | 7 |
inflammatory mediator | 7 |
zinc ribbon | 7 |
similar method | 7 |
fluid samples | 7 |
organic layer | 7 |
diarrhea virus | 7 |
target prediction | 7 |
selection procedures | 7 |
improved potency | 7 |
acid pairs | 7 |
chemical reactions | 7 |
antitumor effects | 7 |
docked poses | 7 |
favorable interactions | 7 |
vitro antiviral | 7 |
novel compound | 7 |
mm compared | 7 |
colloidal dispersions | 7 |
colloidal gold | 7 |
related diseases | 7 |
chemiluminescence kinetics | 7 |
mast cells | 7 |
based substrates | 7 |
san diego | 7 |
intracellular viral | 7 |
therapeutic options | 7 |
nmr screening | 7 |
discovery process | 7 |
readily available | 7 |
bioactive components | 7 |
rna level | 7 |
based metabolomics | 7 |
novel inhibitors | 7 |
concentration used | 7 |
monocytogenes dna | 7 |
docking method | 7 |
adequate precision | 7 |
specific antibody | 7 |
mice subjected | 7 |
four different | 7 |
less sensitive | 7 |
starting materials | 7 |
synthesized via | 7 |
east asia | 7 |
transcriptional gene | 7 |
signaling molecules | 7 |
forms two | 7 |
three centrality | 7 |
ypf formula | 7 |
humulene epoxide | 7 |
survival rate | 7 |
type glycoprotein | 7 |
well documented | 7 |
long term | 7 |
punta toro | 7 |
assisted laser | 7 |
cysteine cathepsin | 7 |
studies showed | 7 |
phenylboronic acid | 7 |
bond interactions | 7 |
activated ku | 7 |
exchange chromatography | 7 |
fpr antagonist | 7 |
secondary structure | 7 |
weighting factor | 7 |
mass transfer | 7 |
aromatic amines | 7 |
treated cells | 7 |
zikv group | 7 |
using ucsf | 7 |
control values | 7 |
also performed | 7 |
trichloroisocyanuric acid | 7 |
discussed previously | 7 |
mtt assay | 7 |
residues asp | 7 |
two series | 7 |
electrostatic interactions | 7 |
multiscale modeling | 7 |
chcl meoh | 7 |
phosphonates trans | 7 |
string database | 7 |
chemical features | 7 |
multiple comparison | 7 |
enzyme via | 7 |
low concentrations | 7 |
hydrogen phosphate | 7 |
vs process | 7 |
naoh weight | 7 |
adaptive immunity | 7 |
concentration tested | 7 |
reaction time | 7 |
high quality | 7 |
regularized least | 7 |
also noticed | 7 |
microvascular endothelial | 7 |
viral genomes | 7 |
suppressive effect | 7 |
human proteases | 7 |
ionization time | 7 |
heterocyclic amines | 7 |
via activation | 7 |
based compounds | 7 |
solid phase | 7 |
radix sophorae | 7 |
low yield | 7 |
virus life | 7 |
electrochemical paper | 7 |
inhibitory protein | 7 |
also detected | 7 |
nuclease resistance | 6 |
first nt | 6 |
spectroscopic methods | 6 |
pichia pastoris | 6 |
aziridine analog | 6 |
exposed surface | 6 |
results demonstrated | 6 |
dmf technology | 6 |
common colds | 6 |
compounds will | 6 |
highly conserved | 6 |
avance instrument | 6 |
probe cathepsin | 6 |
using sodium | 6 |
autoimmune diseases | 6 |
dengue infection | 6 |
dependent activation | 6 |
powerful deshielding | 6 |
acid delivery | 6 |
blood sample | 6 |
second gradient | 6 |
photosensitized oxidation | 6 |
inhibited plasmodial | 6 |
test set | 6 |
potential phytochemical | 6 |
studies revealed | 6 |
electrochemiluminescence detection | 6 |
polyethylene glycol | 6 |
transfer efficiency | 6 |
thermal stability | 6 |
murine norovirus | 6 |
raman lines | 6 |
using gold | 6 |
pharmacological evaluation | 6 |
agents synthesis | 6 |
exhibited inhibition | 6 |
ray structure | 6 |
culture supernatants | 6 |
virus titer | 6 |
simulations showed | 6 |
radix bupleuri | 6 |
inhibitors using | 6 |
mangiferin showed | 6 |
containing dota | 6 |
novel small | 6 |
findings suggested | 6 |
dose group | 6 |
highly correlated | 6 |
fy aptamer | 6 |
lung deposition | 6 |
potentially harmful | 6 |
dotted lines | 6 |
proinflammatory cytokines | 6 |
promotes apoptosis | 6 |
anionic dye | 6 |
activation energy | 6 |
aerobic strains | 6 |
orally bioavailable | 6 |
gly ala | 6 |
based channel | 6 |
experimentally validated | 6 |
mg ece | 6 |
stretching vibration | 6 |
increasing interest | 6 |
myeloid differentiation | 6 |
palm civet | 6 |
exhibit significant | 6 |
diffusing molecules | 6 |
vascular smooth | 6 |
coronavirus spike | 6 |
reversible inhibitors | 6 |
diphenyl phosphoric | 6 |
pathogenic viruses | 6 |
coupled receptors | 6 |
fs time | 6 |
dye radical | 6 |
clickable acetylene | 6 |
including hela | 6 |
santa cruz | 6 |
benzyl bromide | 6 |
organic molecules | 6 |
reduced labeling | 6 |
covalent bonds | 6 |
novel antiviral | 6 |
based inhibitor | 6 |
extensively used | 6 |
venenum bufonis | 6 |
paramagnetic nmr | 6 |
noise ratio | 6 |
approach based | 6 |
gastroenteritis virus | 6 |
large amounts | 6 |
broadly neutralizing | 6 |
active center | 6 |
cancer patients | 6 |
induced cytopathicity | 6 |
buffered saline | 6 |
ovarian carcinoma | 6 |
determine whether | 6 |
thrombin inhibitors | 6 |
conventional solvents | 6 |
therapeutic agent | 6 |
showed high | 6 |
web server | 6 |
viral inhibition | 6 |
computational model | 6 |
detection involves | 6 |
lower respiratory | 6 |
clinical samples | 6 |
lanthanide containing | 6 |
chronic hepatitis | 6 |
incubation period | 6 |
radioactive reagents | 6 |
hiv gp | 6 |
peak intensities | 6 |
white solid | 6 |
sodium dodecyl | 6 |
several examples | 6 |
protonated piperazine | 6 |
immunosorbent assay | 6 |
bond donor | 6 |
two types | 6 |
benzoyl group | 6 |
synthetic procedure | 6 |
structural similarity | 6 |
cell extracts | 6 |
pyridine ring | 6 |
colidna topoisomerase | 6 |
nmr chemical | 6 |
pyrazole compounds | 6 |
targeted chemical | 6 |
dna sequences | 6 |
graphpad software | 6 |
chymotrypsin inhibitor | 6 |
isoxazolidine cycloadducts | 6 |
santa clara | 6 |
correlation spectroscopy | 6 |
second type | 6 |
mbl cells | 6 |
syzygium samarangense | 6 |
scavenging free | 6 |
dee mixture | 6 |
ala val | 6 |
molecular structure | 6 |
strong labeling | 6 |
different nmr | 6 |
many years | 6 |
hcv agents | 6 |
spraying biscao | 6 |
induce autophagy | 6 |
anticancer potential | 6 |
kinase activation | 6 |
spike receptor | 6 |
serial dilution | 6 |
two separate | 6 |
messenger rna | 6 |
time step | 6 |
assay protocols | 6 |
potent cathepsin | 6 |
leukemia cells | 6 |
healthy human | 6 |
specific sirna | 6 |
similar fashion | 6 |
bacteriophage ms | 6 |
solubility class | 6 |
labeling due | 6 |
also included | 6 |
na protein | 6 |
rhizoma alismatis | 6 |
effective anti | 6 |
coworkers described | 6 |
interfering rnas | 6 |
properties make | 6 |
desthiobiotinylated analog | 6 |
halogen substitution | 6 |
ph adjustment | 6 |
plasmodial protease | 6 |
conventional lamp | 6 |
antifungal agents | 6 |
decahydroisoquinoline scaffold | 6 |
narcissus pseudonarcissus | 6 |
pulmonary inflammation | 6 |
using simple | 6 |
induced asthma | 6 |
done using | 6 |
bromo phenyl | 6 |
swissadme using | 6 |
may act | 6 |
receptor agonists | 6 |
promising compounds | 6 |
crude extracts | 6 |
human cervix | 6 |
receptor ligands | 6 |
elimination route | 6 |
tmprss protein | 6 |
docking calculations | 6 |
sophorae flavescentis | 6 |
flow control | 6 |
hiv protease | 6 |
target based | 6 |
diffusion method | 6 |
mitochondrial dysfunction | 6 |
color coded | 6 |
genomic rna | 6 |
quinazolinone moiety | 6 |
class predicted | 6 |
microbicidal efficacy | 6 |
cytokine il | 6 |
side product | 6 |
ligands bind | 6 |
gain access | 6 |
functional characterization | 6 |
future perspectives | 6 |
myocardial infarction | 6 |
recent developments | 6 |
synthetic process | 6 |
contour maps | 6 |
betweenness centrality | 6 |
inhibits hiv | 6 |
biological systems | 6 |
mmol te | 6 |
cell lymphoma | 6 |
closeness centrality | 6 |
vero cell | 6 |
unadsorbed fraction | 6 |
rnai technology | 6 |
column temperature | 6 |
inflammasome assay | 6 |
cellular extracts | 6 |
single crystal | 6 |
low counts | 6 |
proteins involved | 6 |
leu phe | 6 |
suan zao | 6 |
serum samples | 6 |
rhizoma anemarrhenae | 6 |
chronic inflammatory | 6 |
drug analysis | 6 |
induced inflammatory | 6 |
carbon atom | 6 |
horseradish peroxidase | 6 |
detecting agents | 6 |
cultured cells | 6 |
quinazolinone derivatives | 6 |
calcium flux | 6 |
systematic evolution | 6 |
weaker binding | 6 |
desorption ionization | 6 |
pharmacokinetic behavior | 6 |
inflammatory disorders | 6 |
complement activation | 6 |
similar approach | 6 |
also displayed | 6 |
protease structure | 6 |
crystallographic structure | 6 |
mitochondrial pathway | 6 |
flow cytometric | 6 |
isatis indigotica | 6 |
stable rmsd | 6 |
amine radical | 6 |
duplex rna | 6 |
propionibacterium acnes | 6 |
kg dose | 6 |
magnetic beads | 6 |
glycosidic bond | 6 |
relative configuration | 6 |
may possess | 6 |