Questions

This is a list of all the questions and their associated study carrel identifiers. One can learn a lot of the "aboutness" of a text simply by reading the questions.

identifier question
cord-280292-90i45kjkAcetaminophen( APAP) hepatotoxicity is n't it time for APAP to go away?
cord-003341-z5w56zeqThe case for the multifunctional NS3 protein from dengue virus as a target Strategies for development of dengue virus inhibitors Dengue: Guidelines for Diagnosis, Treatment, Prevention and Control; World Health Organization Protective efficacy of the recombinant, live- attenuated, CYD tetravalent dengue vaccine in thai schoolchildren: A randomised, controlled phase 2b trial Dengue vaccine development: A 75% solution?
cord-280807-0g1uo0rd-What is Missing?
cord-034363-6uscua0yBeyond monoamines Pathophysiology of depression: Do we have any solid evidence of interest to clinicians?
cord-291180-xurmzmwjAre we nearly there yet?
cord-254194-962vynwkA hazardous threat to the environment and human health?
cord-254194-962vynwkDoes the antibacterial activity of silver nanoparticles depend on the shape of the nanoparticle?
cord-284113-qboon2uvHow Different Are Their Essential Oil Profile and Antimicrobial Activity?
cord-276781-ujvkcz4swhat happened in the clinical trials and why might the drug have failed?
cord-287754-dh6abx2tGalanthus nivalis agglutinin( GNA)-related lectins: Traditional proteins, burgeoning drugs?
cord-316474-407bthqjIs there any pattern exists in propagationrelated TUPs?
cord-347992-coby2m6eIn vitro selection procedures for identifying DNA and RNA aptamers targeted to nucleic acids and proteins Berzal- Herranz, A. RNA selection and evolution in vitro: powerful techniques for the analysis and identification of new molecular tools Aptamers: a new class of oligonucleotides in the drug discovery pipeline?
cord-355685-wgad0eohTowards prediction paradise?
cord-281281-knelqmzxA fight for supremacy Type 1 interferons and the virus- host relationship: A lesson in détente Viruses and Interferons Recent insights into emerging coronaviruses Clinical characteristics of coronavirus disease 2019 in China Coronavirus infections and immune responses Complement activation contributes to severe acute respiratory syndrome coronavirus pathogenesis Complement as a target in COVID-19?
cord-281281-knelqmzxShould we stimulate or suppress immune responses in COVID-19?
cord-276598-tm0yj2snThe tribological study of novel phosphorous- nitrogen type phosphoramidate additives in rapeseed oil Halogenated flame retardants: Do the fire safety benefits justify the risks?
cord-013412-gj443yeiIs antimicrobial resistance a slowly emerging disaster?
cord-013412-gj443yeiThe G- Quadruplex/ Helicase World as a Potential Antiviral Approach against COVID-19 Targets and tools in antiviral therapy G- quadruplexes in pathogens: A common route to virulence control?
cord-013412-gj443yeiType III Photochemical Mechanism?
cord-349672-2kt7xw8iA Novel Candidate Gene in Juvenile Myoclonic Epilepsy?
cord-349672-2kt7xw8itopoisomerase I conserved for interaction with a specific cytosine base to facilitate DNA cleavage Synthesizing topological structures containing RNA Type IA topoisomerases: A simple puzzle?
cord-287123-ldkuwcc7What formyl peptide receptors, if any, are triggered by compound 43 and lipoxin a4?
cord-287123-ldkuwcc7What makes them special?
cord-281668-960trqexCathepsin L targeting in cancer treatment Cathepsin L, target in cancer treatment?
cord-281668-960trqexThe Future of Cysteine Cathepsins in Disease Management Cysteine proteases as therapeutic targets: Does selectivity matter?
cord-281668-960trqexThe first step towards selective irreversible inhibitors? 64) as Inhibitors of Cysteine Proteases
cord-344175-e2m9o8c2Angiotensin receptor blockers as tentative SARS- CoV-2 therapeutics Can chinese medicine be used for prevention of corona virus disease 2019( COVID-19)?
cord-344175-e2m9o8c2Developing new drugs or repurposing old ones?
cord-344175-e2m9o8c2Did ebola survivors use plant medicines, and if so, which ones?
cord-344175-e2m9o8c2Is there a hope from treatment with cardiovascular drugs?
cord-307731-a2fqmaly2020, 8, 246 Single- molecule pulling simulations can discern active from inactive enzyme inhibitors The light and dark sides of virtual screening: What is there to know?
cord-307731-a2fqmalyAn endless staircase?
cord-307731-a2fqmalyHow do small molecule aggregates inhibit enzyme activity?
cord-272465-i2l4cq8h1-trans- tetramethoxystilbene, a new analogue of resveratrol, inhibits gefitinb- resistant non- small cell lung cancer via selectively elevating intracellular calcium level Autophagy in chronic obstructive pulmonary disease: Homeostatic or pathogenic mechanism?
cord-272465-i2l4cq8hAn"old- age"disease with an"age- old"solution Potential therapeutic effects of curcumin, the anti- inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases Curcumin and cancer cells: How many ways can curry kill tumor cells selectively?
cord-272465-i2l4cq8hCan autophagy promote longevity?
cord-272465-i2l4cq8hLoch ness monster or endangered species?
cord-334511-lx9608vy: Is It Really$ 802 Million?
cord-334511-lx9608vyHow Much NMR Data Is Required to Determine a Protein- Ligand Complex Structure?
cord-334511-lx9608vyRecent developments and new frontiers for targeting multi- protein complexes Screening protein- Single stranded RNA complexes by NMR spectroscopy for structure determination Intramolecularly stapled amphipathic peptides via a boron- sugar interaction Structure determination using solution NMR: Is it worth the effort?
cord-334511-lx9608vyWhat Is the Question?
cord-334511-lx9608vyWhy not?
cord-309722-04pp3lv0: What's new?
cord-309722-04pp3lv0A review Influence of particle size on regional lung deposition- what evidence is there?
cord-309722-04pp3lv0An unsuccessful host defence mechanism providing a safety shelter for the bacteria?
cord-309722-04pp3lv0Delivering on the promise?
cord-309722-04pp3lv0How can we improve the therapeutic efficacy of RNAi in combating infections to make it clinically relevant?
cord-309722-04pp3lv0How can we minimize the undesirable effects when cytokines/ chemokines are being targeted?
cord-309722-04pp3lv0In Molecular Regulation of Endocytosis Nuclear entry of nonviral vectors Pulmonary administration of small interfering RNA: The route to go?
cord-309722-04pp3lv0RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription Barrier or carrier?
cord-309722-04pp3lv0When the respiratory functions are compromised in patients with lung disease, is pulmonary delivery a suitable route for administration?
cord-256838-8rzibpblA clue to Balkan endemic nephropathy?
cord-256838-8rzibpblAdverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids Is there an association between ephedra and heart failure?
cord-256838-8rzibpblAre these molecules specific for that specific activity of a TCM formula or herbs?
cord-256838-8rzibpblCould a specific ADR come from interactions between specific active molecules?
cord-256838-8rzibpblCould the gut microbiota reconcile the oral bioavailability conundrum of traditional herbs?
cord-256838-8rzibpblCould these activities be extrapolated into humans?
cord-256838-8rzibpblCould these inactive ingredients be omitted?
cord-256838-8rzibpblCould they reach a minimal serum level to exert that particular pharmacologic activity in humans?
cord-256838-8rzibpblDoes publication bias exist so that undesired pharmacologic effects are not published?
cord-256838-8rzibpblIs it possible that a particular gene is prone to a specific ADR of a TCM formula or herbs?
cord-256838-8rzibpblIs it possible that herbs and TCM formulas can be effective in this low concentration of bioactive compounds?
cord-256838-8rzibpblIs it possible that interactions between active molecules, e.g., synergism, but not active molecules themselves, account for a specific activity?
cord-256838-8rzibpblIs it possible that little amount of bioactive molecules can cause interactions?
cord-256838-8rzibpblIs it possible that new active molecules are generated during preparation of the TCM formula?
cord-256838-8rzibpblIs it possible that the clinical effects of herbs and TCM formulas can be effective with such a small amount of bioactive compounds?
cord-256838-8rzibpblIs it possible that there might be unidentified active molecules that actually account for a particular pharmacologic activity?
cord-256838-8rzibpblIs there a specific gene or single nucleotide polymorphism( SNP) largely affecting the pharmacokinetic profile?
cord-256838-8rzibpblPositive or Negative Actors?