quadgram

This is a table of type quadgram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

quadgram frequency
severe acute respiratory syndrome118
angiotensin ii type receptor97
acute respiratory distress syndrome82
of angiotensin converting enzyme79
acute respiratory syndrome coronavirus69
in the pathogenesis of62
has been shown to59
of ang ii and58
for the treatment of52
in the regulation of52
ang ii to ang52
of ace in the52
on the other hand50
in the treatment of49
of the ace ang48
effects of ang ii46
actions of ang ii46
an important role in46
of ang ii in44
in the presence of43
ang i to ang42
angiotensin i to angiotensin42
ace ang ii at39
in the development of38
levels of ang ii38
role of ace in38
vascular smooth muscle cells37
ang ii at r36
of ang ii to36
in patients with covid36
the role of the35
the central nervous system35
ang ii in the34
in the present study34
the renin angiotensin system34
converts angiotensin i to33
as well as the33
role of angiotensin converting31
role of the renin31
in vitro and in31
vitro and in vivo31
of the at receptor31
ang ii and ang31
in addition to the30
expression of ace in30
studies have shown that30
the formation of ang30
of ace and ace30
in spontaneously hypertensive rats30
vascular endothelial growth factor30
i and ang ii29
a functional receptor for29
ang i and ang29
a human homolog of28
at and at receptors28
hydrolysis of biological peptides28
components of the ras28
biological peptides by human28
of biological peptides by28
and functional expression as27
the conversion of ang27
functional receptor for sars27
patients with heart failure27
concentrations of ang ii27
plays an important role27
and angiotensin ii receptor27
cloning and functional expression27
been shown to be27
functional expression as a27
an essential regulator of26
conversion of ang ii26
the angiotensin ii type26
severe acute lung failure26
a crucial role of26
crucial role of angiotensin26
the role of ace25
have been shown to25
ii at r axis25
receptor for the sars25
of the renin angiotensin25
human homolog of angiotensin25
peptides by human angiotensin25
essential regulator of heart25
regulator of heart function25
angiotensin ii receptor blockers25
converting enzyme protects from25
in the central nervous25
of the mas receptor24
of severe acute respiratory24
from severe acute lung24
is an essential regulator24
is a functional receptor24
the ang tie system24
functional receptor for the24
the effects of ang24
the activation of the24
in a rat model24
systematic review and meta24
protects from severe acute23
as a result of23
converting enzyme inhibitors and23
converting enzyme and angiotensin23
conversion of ang i23
the functional receptor for23
enzyme is an essential23
is an endogenous ligand22
step in understanding sars22
enzyme protects from severe22
endogenous ligand for the22
a first step in22
an endogenous ligand for22
in understanding sars pathogenesis22
receptor for sars coronavirus22
ligand for the g22
the beneficial effects of22
first step in understanding22
is one of the22
play a role in22
for the sars coronavirus22
a rat model of22
of ang i to22
expression as a captopril22
of the ras in22
in the pathophysiology of22
is protected by copyright21
to the development of21
in patients with heart21
distribution of ace protein21
angiotensin converting enzyme in21
tissue distribution of ace21
article is protected by21
in acute respiratory distress21
this article is protected21
was found to be21
ang ii and na21
converting enzyme is a21
a role in the20
in patients with chronic20
for the development of20
in the absence of20
converting enzyme inhibition and20
a systematic review and20
of the ang ii20
in the cardiovascular system20
a crucial role in20
as well as in20
enzyme is a functional19
the production of ang19
has been reported to19
of acute lung injury19
at receptors in the19
axis of the renin19
a retrospective cohort study19
effects of ace inhibitors19
ace and ace in19
one of the most19
r and at r19
the severe acute respiratory19
enzyme inhibition and angiotensin19
enzyme inhibitors and angiotensin19
converting enzyme in the19
the ace ang ii19
for the g protein19
in the case of19
patients with coronavirus disease19
be involved in the19
women with normal pregnancies18
at r and at18
on the surface of18
a mouse model of18
angiotensin converting enzyme inhibition18
the actions of ang18
formation of ang ii18
ang ii type receptor18
converting enzyme is an18
the expression of ace18
for the first time18
converting enzyme activity in18
of the reninangiotensin system18
of the angiotensin ii18
for the synthesis of17
inhibitors and angiotensin receptor17
role of the ace17
production of ang ii17
in vascular smooth muscle17
the angiotensin converting enzyme17
those of ang ii17
inhibition and angiotensin ii17
play an important role17
in the context of17
of angiotensin ii in17
by the action of16
inhibitors in patients with16
in a mouse model16
blockade of the renin16
in patients with severe16
in a variety of16
ace expression in the16
is involved in the16
increased ang ii levels16
angiotensin ii in the16
both ace and ace16
of the ace gene15
a l p r15
and angiotensin receptor blockers15
it was found that15
j o u r15
u r n a15
in the heart and15
expression of ace and15
i to ang ii15
as shown in fig15
n a l p15
r n a l15
the structure of the15
regulated ectodomain shedding of15
p r o o15
effect of ang ii15
mediates regulated ectodomain shedding15
induced by ang ii15
role in the pathogenesis15
ectodomain shedding of the15
o u r n15
no conflict of interest15
the concentrations of ang15
r o o f15
l p r e15
increase in ang ii14
it is known that14
of ace expression in14
the effects of the14
angiotensin ii and angiotensin14
the ras in the14
n mice per group14
and risk factors for14
regulation of blood pressure14
it has been shown14
the levels of ang14
regulator of the renin14
components of the renin14
the effects of ace14
in the spontaneously hypertensive14
respiratory syndrome coronavirus infection14
shedding of the severe14
spike protein of sars14
ang ii levels in14
may contribute to the14
effect of angiotensin ii14
in patients with hypertension14
in addition to its14
to the formation of14
of patients with covid14
a wide variety of14
of angiotensin ii type13
and is associated with13
in animal models of13
benefits of ace inhibition13
a central role in13
inhibitors and angiotensin ii13
expression profiling of ace13
and smooth muscle cells13
ii receptor blockers on13
ace and tmprss and13
it has been found13
the sympathetic nervous system13
of the nlrp inflammasome13
the presence of the13
in patients with type13
in failing human heart13
in experimental models of13
the aim of this13
an essential role in13
the activity of the13
expression of at r13
of angiotensin ii and13
may be involved in13
it has been reported13
receptor blockers on cardiac13
our understanding of the13
the treatment of covid13
ace inhibitors and arbs13
middle east respiratory syndrome13
as a receptor for13
the expression of mir13
the synthesis of the13
plays a role in13
structure and function of13
the rostral ventrolateral medulla13
the spike protein of13
of ang i and13
with an increase in13
a critical role in13
a key role in13
levels of ace and13
ace expression in rat13
and angiotensin converting enzyme13
in acute lung injury13
as a therapeutic target12
of reactive oxygen species12
clinical course and risk12
system inhibitors in patients12
this work was supported12
a wide range of12
the upregulation of mir12
of ang ii by12
the discovery of ace12
course and risk factors12
the importance of ace12
depends on ace and12
in the gastrointestinal tract12
apelin ko mice showed12
mortality of adult inpatients12
renin angiotensin system in12
arm of the ras12
role for ace in12
the spontaneously hypertensive rat12
blocked by a clinically12
for mortality of adult12
entry depends on ace12
ii and na in12
important role in the12
in the metabolism of12
prevention and treatment of12
risk factors for mortality12
the classical raas axis12
angiotensin ii receptor antagonist12
aldosterone system inhibitors in12
factors for mortality of12
cell entry depends on12
to be associated with12
and is blocked by12
of ace inhibitors and12
role of angiotensin ii12
of the ace angiotensin12
of hospitalized patients with12
induced acute lung injury12
by the use of12
by a clinically proven12
it is possible that12
adult inpatients with covid12
is blocked by a12
of ace and ang12
of adult inpatients with12
the development of new12
of angiotensin ii receptors12
ace in the heart12
clinically proven protease inhibitor12
of the ras and12
mortality in patients with12
concentration of ang ii12
on ace and tmprss12
of the brain ras12
tmprss and is blocked12
angiotensin system in the12
a clinically proven protease12
was associated with increased12
to be involved in12
is highly expressed in12
and tmprss and is12
the first time that11
been identified in the11
work was supported by11
have been identified in11
blockers on cardiac angiotensin11
ace inhibitors and at11
and ang ii to11
in ace knockout mice11
at the same time11
in women with pe11
ang ii into ang11
patients with chronic heart11
in the progression of11
converting enzyme in human11
has been found to11
that the expression of11
the generation of ang11
are presented as the11
in contrast to the11
efficacy and safety of11
the involvement of the11
also been shown to11
ang i and ii11
the development of cardiac11
converting enzyme inhibition in11
be due to the11
in apelin ko mice11
the role of ang11
in the production of11
therapy in patients with11
activation of the ace11
forming activity in failing11
the effect of angiotensin11
ii in the brain11
it is important to11
the angiotensin type receptor11
presented as the mean11
has been shown that11
with chronic heart failure11
ii type receptor blockade11
ang i or ang11
activity in failing human11
may be due to11
ang ii levels were11
the results showed that11
the balance between the11
and h c cells11
studies are needed to11
ang ii binds to11
compared to ang ii11
ang i into ang11
a reduction in the11
of the activation of11
the antihypertensive effects of11
morbidity and mortality in11
of the role of11
role in the regulation11
and chronic kidney disease11
angiotensin i converting enzyme11
disease control and prevention11
for disease control and11
through activation of the11
induced lung injury angiotensin11
patients with type diabetes11
in ang ii levels10
the authors declare that10
syndrome coronavirus spike protein10
and vascular smooth muscle10
of angiotensin ii receptor10
the existence of a10
for the recognition of10
the pathogenesis of covid10
in engineered human tissues10
plays a crucial role10
structural basis for the10
with acute respiratory distress10
with the development of10
in patients with acute10
in the generation of10
for upregulation of the10
of the at r10
in the kidney of10
in a study of10
a therapeutic target for10
in women with normal10
has been found that10
effect of ace inhibition10
activation of the mas10
at least in part10
in health and disease10
in the brain and10
has been associated with10
level of ang ii10
may play a role10
of the classical ras10
in the setting of10
the structure and function10
in ace transgenic mice10
clinical characteristics of coronavirus10
levels of ace in10
engineered human tissues using10
we have shown that10
a potential target for10
the effect of the10
regulation of cell volume10
has been suggested that10
it has been suggested10
to an increase in10
on the basis of10
aortic smooth muscle cells10
an increase in the10
in the ang ii10
were found to be10
rats with myocardial infarction10
studies have demonstrated that10
the use of ace10
evidence for upregulation of10
involved in the pathogenesis10
data are presented as10
of coronavirus disease in10
converting enzyme inhibition on10
in the ace gene10
the treatment of hypertension10
have shown that the10
of the effects of10
of recombinant human angiotensin10
endothelial nitric oxide synthase10
angiotensin ii at receptor10
that the use of10
effects of angiotensin ii10
the protective role of10
respiratory syndrome coronavirus spike10
metabolite formation rate of10
the complexity of the10
and ace in the10
induced cardiac hypertrophy and10
failing human heart ventricles10
an increase in ace10
the components of the10
the metabolite formation rate10
infections in engineered human10
patients infected with sars10
effects of ace inhibition10
characteristics of coronavirus disease10
a significant role in9
did not reach statistical9
in the control of9
the hypotensive effect of9
in a number of9
axis of the ras9
crucial role in the9
the progression of diabetic9
in the course of9
in the formation of9
of human angiotensin i9
is associated with increased9
in patients with diabetes9
in a model of9
of the active site9
an increase in ang9
to the mas receptor9
the benefits of ace9
plasma levels of ang9
the ratio of ace9
these findings suggest that9
for the prevention of9
death in ace transgenic9
and sudden death in9
with chronic kidney disease9
importance of ace in9
center for disease control9
ace inhibitors and angiotensin9
of patients infected with9
was associated with a9
of spontaneously hypertensive rats9
are associated with the9
not reach statistical significance9
of ang ii at9
angiotensin converting enzyme inhibitor9
an important role of9
has been implicated in9
is well known that9
european society of cardiology9
h n virus infection9
plays a key role9
to increased levels of9
of at r in9
of the ang tie9
of the peptide in9
sudden death in ace9
ang ii to the9
beneficial effects of ace9
of the novel coronavirus9
prevention of angiotensin ii9
basis for the recognition9
development of cardiac hypertrophy9
ace activity in the9
system in heart failure9
inhibition of ang ii9
is expressed in the9
in the expression of9
to the antihypertensive effects9
acei or arb use9
an angiotensin ii receptor9
contributes to the antihypertensive9
expression of cyp b9
in the brain of9
the role of angiotensin9
results are presented as9
ang ii by ace9
angiotensin converting enzyme inhibitors9
ace and neprilysin in9
in the current study9
it is well known9
effects of the activation9
coronavirus disease in china9
with type diabetes and9
similar to those of9
patients with severe covid9
the development of heart9
mice with downregulated connexins9
volume and water transport9
regulation of cardiovascular function9
of ace inhibitor therapy9
a negative regulator of9
in patients with left9
ace as a receptor9
by blockade of angiotensin9
cardiac hypertrophy and fibrosis9
has been detected in9
in angiotensin peptide metabolism9
on the regulation of9
acute lung injury in9
components of the raas9
transgenic mice with downregulated9
ace transgenic mice with9
h c cells were9
a role for the9
of the classical raas9
angiotensin converting enzyme activity9
development of heart failure9
patients with novel coronavirus9
at r in the9
on angiotensin and bradykinin9
under the control of9
in rats with myocardial9
effects in the cardiovascular9
in critically ill patients9
in patients with coronavirus9
upregulation of the angiotensin9
feb suppressed ang ii9
conversion of angiotensin i9
were significantly higher than9
myocardial infarction in rats9
in blood pressure regulation9
of ace inhibition in9
involved in the regulation9
the ang ii type9
the regulation of the9
the loss of ace9
of the components of9
highly expressed in the9
are involved in the9
degradation of ang ii8
cardiac myocytes through activation8
on the use of8
mrna expression profiling of8
the at receptor in8
effect of resveratrol on8
myocardial infarction by blockade8
the importance of the8
loads and lung injury8
release of nitric oxide8
prevention of pulmonary hypertension8
the generation of angiotensin8
growth of cardiac myocytes8
and vascular endothelial growth8
these results suggest that8
inflammatory effects of ang8
clinical and biochemical indexes8
total rna was isolated8
the regulation of cell8
responses and normal cardiac8
of transforming growth factor8
of vasopressin from the8
ang ii and at8
the therapeutic benefits of8
gene is located on8
homologue ace and neprilysin8
been shown to have8
has also been shown8
i or ang ii8
with novel coronavirus in8
converting enzyme after myocardial8
of ang ii were8
during the progression of8
found that ang ii8
the at receptor gene8
blockade of angiotensin ii8
the alternative raas axis8
of the most important8
converting enzyme homologue ace8
the binding of the8
in the degradation of8
to a reduction in8
to ang ii by8
normal lung tissue and8
elevated ang ii levels8
the concentration of ang8
protective role of ace8
the angiotensin ii at8
to the lack of8
inhibition on angiotensin and8
inhibits growth of cardiac8
its homologue ace and8
was approved by the8
the active site of8
response to ang ii8
by the presence of8
system blockers and the8
ace deficiency accentuates vascular8
patients linked to viral8
vasopressin from the rat8
a decrease in the8
activation of the angiotensin8
myocytes through activation of8
infarction by blockade of8
release of vasopressin from8
was identified as a8
patients with left ventricular8
infected with novel coronavirus8
angiotensin ii type a8
with severe acute respiratory8
infected patients linked to8
deficiency is associated with8
ncov infected patients linked8
tumor necrosis factor alpha8
angiotensin ii production and8
correction for multiple comparisons8
cardiac phenotype in ace8
linked to viral loads8
these data suggest that8
activates the nlrp inflammasome8
blockade of the ras8
high levels of ace8
in human endothelial cells8
the treatment of cardiovascular8
patients treated with ace8
heart failure with reduced8
these data indicate that8
disease and ulcerative colitis8
an angiotensin ii type8
in the human heart8
and neprilysin in angiotensin8
to those of ang8
of angiotensin i to8
the protein expression of8
and oxidative stress in8
human tissues using clinical8
of heart function angiotensin8
and characterization of a8
of the solitary tract8
to the plasma membrane8
effects of blockade of8
of the sympathetic nervous8
ang ii has been8
treatment of cardiovascular disease8
is known to be8
the downregulation of ace8
in individuals with diabetes8
in this study we8
have a role in8
ii type receptor in8
ang ii or ang8
of ang ii on8
viral loads and lung8
converting enzyme activity and8
by angiotensin ii type8
serum ace and ang8
has been found in8
the heart and kidney8
and normal cardiac phenotype8
that they have no8
has been reported that8
antihypertensive effects of blockade8
a novel homologue of8
in patients with coronary8
the synthesis of a8
in the lungs and8
in the synthesis of8
enzyme after myocardial infarction8
of at receptors in8
of the complement system8
is located on chromosome8
to viral loads and8
ace and ace activity8
human airway epithelial cells8
converted to ang ii8
the plasma membrane of8
a protective role in8
is thought to be8
pivotal role of the8
in human airway epithelial8
for the formation of8
and activation of the8
ace is expressed in8
novel homologue of angiotensin8
on the x chromosome8
regulator of the ras8
of cardiac myocytes through8
by angiotensin converting enzyme8
neprilysin in angiotensin peptide8
the expression of the8
and the risk of8
increase in blood pressure8
in the aorta of8
the mechanism of action8
increased ace expression in8
is based on the8
ace inhibitors or arbs8
quantitative mrna expression profiling8
na and h o8
in vascular endothelial cells8
central role in the8
of blockade of the8
homologue of angiotensin converting8
through an angiotensin ii8
levels of ang i8
angiotensin system in heart8
and biochemical indexes from8
a murine model of8
altered blood pressure responses8
in normal lung tissue8
outcomes in patients with8
pressure responses and normal8
ace functions as a8
mas axis of the8
grade soluble human ace8
chinese center for disease8
renin angiotensin aldosterone system8
of components of the8
the regulation of blood8
normal cardiac phenotype in8
blood pressure responses and8
mas axis in the8
and na in serum8
the discovery of the8
in myocardial ischemia reperfusion8
activation of the at8
after myocardial infarction by8
advanced glycation end products8
dysfunction after myocardial infarction8
inhibitors and at receptor7
deficiency accentuates vascular inflammation7
angiotensin converting enzyme type7
development and progression of7
an acei or arb7
have been found to7
to the synthesis of7
national institutes of health7
was shown to be7
ace levels and activity7
to the at r7
genetic deletion of the7
in the lung tumor7
of ace in cardiac7
and ischaemic heart disease7
immunocytochemical expression of ang7
the extracellular domain of7
converting enzyme overexpression in7
in the lungs of7
physiological and pathological effects7
renal immunocytochemical expression of7
lung injury in mice7
of podocyte injury in7
activity in patients with7
article this article is7
after myocardial infarction in7
bending motion important for7
apelin ko mice were7
it was shown that7
and tissue levels of7
vivo and in vitro7
decreased expression of ace7
the angiotensin at receptor7
of ang ii is7
physiology of local renin7
patients with hypertension and7
peptide corresponding to the7
activity of ace in7
angiotensin ii receptor subtypes7
with diabetes infected with7
is not inhibited by7
both ace inhibitors and7
of ang ii or7
therapeutic target for the7
expression of ang ii7
converting enzyme in acute7
it is not surprising7
on the cell surface7
effect of angiotensin converting7
for inhibitor binding and7
on mortality and morbidity7
in vivo and in7
may be associated with7
antigenicity of the sars7
accepted article this article7
inhibitor binding and catalysis7
as well as their7
presence or absence of7
carboxypeptidase a novel angiotensin7
treated apelin ko mice7
accentuates vascular inflammation and7
enzyme in acute respiratory7
in chronic heart failure7
of ace and the7
severe and critical conditions7
was significantly higher in7
at and at receptor7
nucleus of the solitary7
elevation of blood pressure7
model of type diabetes7
function in patients with7
of the ras is7
of vascular endothelial growth7
in chronic kidney disease7
effects of ras blockade7
cell volume and water7
but not in the7
ace in the lungs7
in the apoe knockout7
as compared to the7
the risk of covid7
also contribute to the7
effects of feb on7
is also associated with7
of blood pressure in7
mediates angiotensin converting enzyme7
ray structures reveal a7
further studies are needed7
of the ras are7
has been reported in7
and the expression of7
activation of at r7
in normotensive and hypertensive7
production and cellular responses7
in rat and humans7
cardioprotective effect in myocardial7
in the proximal tubules7
angiotensin ii type i7
enzyme type internalization and7
effect in myocardial ischemia7
normotensive and hypertensive rats7
the renin prorenin receptor7
degradation through an angiotensin7
to a lesser extent7
receptor in angiotensin ii7
to ang ii in7
ang ii is a7
ii for the treatment7
effect of ace inhibitors7
american college of cardiology7
and months after ot7
characteristics of hospitalized patients7
fluid and electrolyte balance7
with ace inhibitor therapy7
myocardial infarction increases ace7
heart failure and ischaemic7
of angiotensin peptides in7
structures reveal a large7
in angiotensin ii production7
angiotensin converting enzyme and7
and the role of7
with left ventricular dysfunction7
motion important for inhibitor7
was significantly reduced in7
failure and ischaemic heart7
of cyp b in7
one of the major7
patients infected with novel7
i to angiotensin ii7
enhanced renal immunocytochemical expression7
of the effect of7
the presence of ace7
genetic ace deficiency accentuates7
with the discovery of7
there is no evidence7
a key regulator of7
outcomes of patients with7
ii production and cellular7
a major role in7
and severe acute respiratory7
ace angiotensin ii at7
plasma clearance of angiotensin7
related to increased levels7
an at receptor antagonist7
of ace and its7
better understanding of the7
ang ii and the7
insensitive carboxypeptidase a novel7
wt and apelin ko7
has a role in7
expression in rat and7
activity is reduced in7
internalization and degradation through7
a role for ace7
of the cytokine storm7
be used as a7
an experimental model of7
converting enzyme and its7
have been linked to7
converting enzyme type internalization7
and degradation through an7
of ace ang ii7
the development and progression7
adult respiratory distress syndrome7
converting enzyme as a7
cyp b protein expression7
in gs bs patients7
prorenin receptor in angiotensin7
of ras in the7
mortality and morbidity in7
treated with ace inhibitor7
the development of a7
protein expression of cyp7
and pathological effects in7
expression of mrnas for7
pulmonary artery smooth muscle7
statistical significance was assessed7
a pilot clinical trial7
type internalization and degradation7
in the active site7
and cellular responses to7
the apoe knockout mouse7
action of ang ii7
features of patients infected7
high ang ii levels7
of the renin prorenin7
ace i d polymorphism7
in heart failure and7
ace in heart failure7
airway epithelial cells and7
counteract the effects of7
the formation of a7
an ace inhibitor or7
the early stages of7
of the complement cascade7
declare that they have7
pathological effects in the7
the lung tumor tissue7
that ang ii could7
vascular inflammation and atherosclerosis7
tissue levels of ang7
mediated by ang ii7
in the hearts of7
a high level of7
polymorphism is associated with7
ii type i receptor7
is the result of7
chronic obstructive pulmonary disease7
in the levels of7
na in serum of7
i into ang ii7
activation of the ang7
influenza a h n7
angiotensin ii for the7
patients with chronic kidney7
in a range of7
ii mediates angiotensin converting7
avian influenza a h7
significance was assessed by7
ace and ace levels7
the catalytic activity of7
angiotensin ii mediates angiotensin7
was carried out using7
a direct effect on7
and the healthy individuals7
due to the lack7
have been identified as7
the presence of a7
in normal pregnant women7
converting enzyme gene family7
of blood pressure and7
view of the ras7
in the nucleus tractus7
the bradykinin b receptor7
and atherosclerosis in the7
the authors declare no7
increased levels of ang7
ii type a receptor7
atherosclerosis in the apoe7
increases ace expression in7
reduction of ang ii7
the plasma levels of7
the results of this7
the progression of hfmd7
angiotensin system in cardiovascular7
a single amino acid7
the ras has been7
the angiotensin ii receptor7
patients and the healthy7
the important role of7
for ace and ace7
a new class of7
on mortality in patients7
important for inhibitor binding7
the pathogenesis of severe7
in ace null mice7
as a consequence of7
a significant reduction of7
in a murine model7
inflammation and atherosclerosis in7
of ang ii levels7
oxidative stress in the7
clinical features of patients7
the nlrp inflammasome in7
from the venom of7
infarction increases ace expression7
on the role of7
experimental and clinical studies7
reveal a large hinge7
cardiac hypertrophy induced by7
after acute myocardial infarction7
component of the renin7
for the design of7
and ace during pregnancy7
mas receptor axis in7
shown to be a7
patients with coronary artery7
of morbidity and mortality7
the protective arm of7
from the rat hypothalamo7
degradation of angiotensin ii7
activation of the complement7
of the expression of7
of acute respiratory distress7
with coronary artery disease7
angiotensin ii cell signaling7
hospitalized patients with novel7
in the rostral ventrolateral7
clinical characteristics of hospitalized7
cellular responses to renin7
via the at receptor7
progression of diabetic nephropathy7
was significantly increased in7
data were analyzed using7
in the subfornical organ6
and its role in6
of both ace and6
ace is widely expressed6
ace is not inhibited6
and at receptor antagonists6
of this study is6
the course of the6
classified as bs type6
of recombinant human ace6
angiotensin ii receptor type6
binding domain complexed with6
in endothelial cells and6
of cell volume and6
with preserved ejection fraction6
may be related to6
ncov spike in the6
ras in the lung6
a new coronavirus of6
of a variety of6
through the activation of6
the crystal structure of6
ang ii in combination6
em structure of the6
functions as a carboxypeptidase6
ace differentially and only6
unmasked during combined treatment6
in the cytokine storm6
is mediated by the6
have been proposed to6
patients with hypertension hospitalized6
driven by the severe6
coronavirus of probable bat6
and functional roles of6
implicated in the pathogenesis6
in congestive heart failure6
has been demonstrated that6
entry driven by the6
the development of neurogenic6
is also involved in6
studies have indicated that6
ards and septic shock6
gs and bs patients6
therapeutic benefits of ace6
the ace expression in6
the at r is6
care and use committee6
solid phase peptide synthesis6
to the use of6
induced by h n6
and potential therapeutic target6
in the prefusion conformation6
of the amino acid6
play a central role6
as part of the6
entry into host cells6
in ang ii and6
and blood pressure in6
diabetic nephropathy in mice6
and risk of covid6
functional roles of angiotensin6
the expression of at6
a recent study by6
is increased in the6
hospitalized patients with covid6
the actions of ace6
at or at receptor6
a new target for6
effects on blood pressure6
ang ii levels and6
only proteolysis by tmprss6
sodium and water retention6
cells of the kidney6
two active sites of6
there was no significant6
in cardiac and renal6
has been described to6
plays an essential role6
this study was supported6
activation of the ras6
a decrease in ace6
mechanism of action of6
and the at r6
ii in combination with6
human research ethics committee6
of angiotensin receptor blockers6
ang ii to form6
on the cell membrane6
partner for amino acid6
fibrosis and pulmonary hypertension6
the severity of the6
new coronavirus of probable6
analysis of randomized controlled6
angiotensin ii at r6
and multiple comparisons were6
metabolism of ang ii6
ratio of ace to6
ace to ace expression6
cleave ace differentially and6
and activity of ace6
biochemical and functional roles6
and only proteolysis by6
podocytes cultured in vitro6
have been associated with6
as post hoc test6
any increase of endocan6
the levels of ace6
activation promotes antithrombotic activity6
ang ii from ang6
ace activation promotes antithrombotic6
by the at receptor6
the action of ace6
nuclear factor kappa b6
the influence of the6
and h o reabsorption6
ace and ang ii6
tmprss augments entry driven6
severe cases of covid6
activation of the nlrp6
authors declare that they6
is identical to the6
renin prorenin receptor in6
diabetic kidney disease and6
failure after myocardial infarction6
authors declare no conflict6
of blood pressure by6
of the ras has6
at the end of6
the european society of6
the presence or absence6
and regulator of the6
of probable bat origin6
vascular smooth muscle cell6
both at and at6
of the present study6
ace expression and activity6
with lisinopril and losartan6
angiotensin converting enzyme gene6
lung fibrosis and pulmonary6
increase the expression of6
reduces blood pressure and6
is also found in6
mrna and protein expression6
in proximal tubular cells6
to be the major6
ang ii and its6
declare no conflict of6
was not able to6
for the generation of6
the c domain of6
examined the effects of6
the effect of ang6
the expression levels of6
min at room temperature6
enzyme inhibition on angiotensin6
are presented as mean6
human recombinant ace reduces6
with diabetic kidney disease6
a large number of6
the glomerular basement membrane6
angiotensinogen to ang i6
of the central nervous6
the deleterious effects of6
aim of this study6
the development of novel6
and apelin ko mice6
the recognition of the6
might be involved in6
as a potential therapeutic6
ventricular dysfunction after myocardial6
h n influenza virus6
has been identified in6
negative regulator of the6
been found to be6
the immune system is6
by the severe acute6
homologous domains of human6
during combined treatment with6
a partner for amino6
hypotensive effect of bradykinin6
are mediated by the6
a systematic review of6
downregulation of the ace6
comparisons were made by6
and recombinant human ace6
a peptidase in the6
is not surprising that6
the peptide in the6
chronic cigarette smoke exposure6
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convert ang i to6
the action of ang6
in lung tumor tissue6
soluble form of ace6
decrease in blood pressure6
treated for h with6
it is likely that6
of ang ii into6
a pneumonia outbreak associated6
molecular mechanisms and potential6
weight to body weight6
for the preparation of6
outbreak associated with a6
an animal model of6
axes of the ras6
vasodepressor actions of angiotensin6
ace activity ace ratio6
with a new coronavirus6
artery smooth muscle cells6
receptor mas knockout mice6
the prevention and treatment6
b and its associated6
in view of the6
of in vitro and6
in experimental heart failure6
have been reported in6
in the processing of6
disease and heart failure6
stimulation of the ace6
administration of ang ii6
of an ace inhibitor6
the increase in ang6
development of neurogenic hypertension6
of ace in cardiovascular6
plays a critical role6
it has been proposed6
the development of hypertension6
nonproteolytic activation of prorenin6
response to myocardial infarction6
mediated by at receptors6
stimulation of at r6
at receptor in the6
have been found in6
blood flow and oxygenation6
effects of losartan on6
of ace to ace6
overexpression of human angiotensin6
sodium and water absorption6
critical conditions of covid6
catalytic activity of ace6
converting enzyme by the6
and ace activity in6
a significant increase in6
be one of the6
may serve as a6
the american heart association6
and bradykinin peptides in6
by a variety of6
treatment with lisinopril and6
blood pressure in the6
mediated by the at6
is responsible for the6
the pathogenesis of sars6
reduction in ang ii6
aged apelin ko mice6
a potential therapeutic target6
was not associated with6
of at r and6
a disintegrin and metalloproteinase6
be explained by the6
of tumor necrosis factor6
in accordance with the6
converting enzyme inhibitors angiotensin6
of human airway epithelia6
deletion of the ace6
recombinant ace reduces the6
of angiotensin i and6
we found that the6
multiple comparisons were made6
from the chinese center6
the surface of the6
two homologous domains of6
recombinant human ace in6
pulmonary blood flow and6
pilot clinical trial of6
the apical surface of6
angiotensin ii receptor blocker6
east respiratory syndrome coronavirus6
converting enzyme gene expression6
as well as a6
patients with essential hypertension6
the two active sites6
rna was isolated using6
of angiotensin peptides and6
of severe and critical6
the enzymatic activity of6
pneumonia outbreak associated with6
accumulation of ang ii6
domain of somatic ace6
cells were incubated with6
to the severity of6
mhc ratio and anp6
the intensive care unit6
ace and ace are6
to decrease ang ii6
ii in the heart6
normal and preeclamptic pregnancy6
of the ras with6
protective arm of the6
have shown that ace6
the presence of an6
a receptor for the6
the formation of the6
flow and oxygenation in6
mechanisms and potential therapeutic6
in the process of6
inhibition in patients with6
the chinese center for6
in biochemical and functional6
enzyme in diabetic nephropathy6
pulmonary artery remodeling and6
trial of recombinant human6
target for the prevention6
associated with a new6
in order to improve6
it has been demonstrated6
enzyme as a therapeutic6
to the ace receptor6
in aged apelin ko6
pulmonary vascular remodeling and6
differentially and only proteolysis6
the aim of the6
keuls as post hoc6
enzyme activity in the6
spike in the prefusion6
attenuates the progression of6
alveolar epithelial cells and6
is considered to be6
in both cell lines6
a member of the6
in an attempt to6
at r axis in6
the at receptor is6
in an experimental model6
ace reduces the progression6
circulating levels of ang6
were approved by the6
the two homologous domains6
induced lung injury in6
lung injury induced by6
domains of human angiotensin6
in the level of6
via activation of the6
and the activation of6
the acute respiratory distress6
the degradation of ang6
by tmprss augments entry6
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levels are associated with6
in hek t cells6
showed that ang ii6
heart failure after myocardial6
in the early s6
clinical outcomes of covid6
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in the shr kidney6
between ace and ace6
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elevated blood pressure in6
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has been proposed that6
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has been demonstrated to6
cell death by pyroptosis6
advances in biochemical and6
and bradykinin peptide levels6
counterregulatory actions of angiotensin6
or at receptor antagonists6
cyp b and its6
and mortality in covid6
patients with vasodilatory shock6
the degradation of angiotensin6
have been detected in6
evidence for a role6
and plasma renin activity6
in vivo heart function6
in response to ang6
were observed in the6
connective tissue growth factor6
and critical conditions of6
neurohypophysial system by angiotensin6
invasion of host cells6
forming enzymes and receptors6
angiotensin and bradykinin peptides6
the biological activity of6
data indicate that the6
in subjects with diabetes6
significantly higher than that6
of the neutral amino6
the ace gene in6
were measured per group6
in the isolated perfused6
proteolysis by tmprss augments6
left ventricular dysfunction after6
epidermal growth factor receptor6
be the result of6
for prevention and treatment6
in normal and preeclamptic6
that activation of the6
to those of the6
to the at receptor6
the serum ace concentration6
expression and activity of6
effects of the ace6
for amino acid transporters6
and antigenicity of the6
heart function in angiotensin6
clinical trial of recombinant6
animal care and use6
cardiovascular effects of angiotensin6
of cardiovascular and renal6
an increased risk of6
angiotensin and bradykinin peptide6
ace expression in human6
endothelial and smooth muscle6
an important regulator of6
of cyp b and6
anova followed by student6
combined treatment with lisinopril6
levels of inflammatory cytokines6
in the failing heart6
of randomized controlled trials6
in blood pressure control6
in the urine of6
and angiotensin ii in6
the ability of the6
to be responsible for6
impairment of in vitro6
lung tissue and lung5
function in hypertensive mice5
the innate immune system5
have no conflict of5
after correction for multiple5
regulated in embryonic kidneys5
vasoprotective axis of the5
protects from lethal avian5
cardiopulmonary protection against lung5
development of glomerulosclerosis in5
single amino acid from5
ace gene expression is5
the ace and ace5
to microbial ecology and5
enalapril in patients with5
ii type receptor antagonists5
in endothelial cells is5
via the mas receptor5
brain impairs baroreflex function5
dysfunction and pathological remodeling5
is converted to ang5
beneficial effects of the5
a soluble form of5
not affect ang ii5
juxtaglomerular cells of the5
that ang ii is5
of ace and is5
angiotensin receptor neprilysin inhibitor5
ii type receptor gene5
respiratory distress syndrome and5
with an ace inhibitor5
located on the x5
it is evident that5
downregulation of ace by5
the vasoprotective axis of5
which is available to5
in the late s5
were analyzed using one5
and at receptor blockers5
levels of ace have5
as novel antihypertensive agents5
in patients with cirrhosis5
ko mice showed a5
through the inhibition of5
in the early stages5
both in vitro and5
the protective effects of5
for virus origins and5
and the american heart5
the nucleus tractus solitarii5
can be used in5
associated with the development5
pharmacokinetics and pharmacodynamics of5
in vessels of shrsp5
of ace in these5
pressure and improves endothelial5
direct effect on the5
local production of ang5
in patients with symptomatic5
ang ii alone group5
expressed in the brain5
the sars outbreak in5
of the actions of5
the control of the5
by binding to the5
or ards induced by5
our results suggest that5
and activator of transcription5
a pivotal role in5
and epidemiology of novel5
angiotensinconverting enzyme is an5
and blood pressure regulation5
specific cell subsets across5
patients at high risk5
upregulation of hepatic angiotensin5
a potent inhibitor of5
human renin and human5
by angiotensin ii in5
is predominantly expressed in5
in a family study5
ace gene is located5
by h n virus5
and enalapril in patients5
have been attributed to5
the s protein of5
for patients with covid5
protection against lung fibrosis5
associated with an increase5
cleavage site in the5
and a decrease in5
may be regulated by5
late development of angiotensin5
of cytokine storm and5
rna expression profiling of5
pulmonary and renal tissues5
enzyme determines plasma clearance5
malnutrition to microbial ecology5
overexpression of ace in5
mas axis confers cardiopulmonary5
a and at b5
in pulmonary and renal5
overexpression in vessels of5
of at r expression5
the national institutes of5
amino acid malnutrition to5
significantly higher than those5
has been demonstrated in5
by the observation that5
treated with ang ii5
study of patients with5
and a partner for5
hek t cells were5
may be responsible for5
enzymatic activity of ace5
the stability of the5
in this work we5
has been proposed to5
patients with diabetes mellitus5
in association with increased5
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china clinical characteristics of5
ang ii and aldosterone5
this suggests that the5
have shown that ang5
is developmentally regulated in5
by the spike protein5
at r has been5
effects of losartan in5
by ace inhibitor therapy5
angiotensin peptides and recombinant5
generation of ang ii5
with ace inhibitors or5
and at receptors in5
cleavage of ang i5
the effects of these5
the conformation of the5
which may explain the5
transporter partners ace and5
oxidative stress and inflammation5
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role in blood pressure5
stimulation of at receptors5
diabetic db db mice5
with acute myocardial infarction5
ecology and intestinal inflammation5
derived vsels and hscs5
characterization of a new5
to the late development5
erk p map kinase5
of ace inhibitors on5
converting enzyme in lung5
terminal glycosylation of ace5
the efficacy and safety5
is due to the5
the receptor for sars5
role in the development5
design and synthesis of5
to the fact that5
as well as its5
in ad compared with5
and facilitates viral entry5
expression as a captoprilinsensitive5
of ace have been5
converting enzyme inhibitors on5
the development of glomerulosclerosis5
to the cell surface5
several studies have shown5
hypertension in transgenic rats5
a potential role for5
important role of the5
from the cell surface5
stimulated gene in human5
for min at room5
the hyperthermophilic archaeon pyrococcus5
from the hyperthermophilic archaeon5
cytokines such as il5
metabolism of angiotensin i5
as a captoprilinsensitive carboxypeptidase5
with high affinity to5
in ace levels in5
we have developed a5
after ang ii infusion5
angiotensin iii in the5
ace in individuals with5
angiotensin system blockers and5
for most of the5
a large body of5
of heart failure after5
final approval of the5
i by neutral endopeptidase5
in regulation of cardiovascular5
effects of ace ang5
in support of this5
development of angiotensin ii5
corrected for multiple comparisons5
with increased ace expression5
cells in the lungs5
the renin angiotensin aldosterone5
vascular cell adhesion molecule5
the ang ii at5
it is clear that5
investigated the effects of5
a single residue from5
enzyme overexpression in vessels5
and the mas receptor5
lung injury in piglets5
in an animal model5
the physiological and pathophysiological5
increase the production of5
activators as novel antihypertensive5
the distribution of the5
of amino acids and5
in h c cells5
in the respiratory system5
the lungs and intestine5
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acid transporter partners ace5
enzyme activators as novel5
blood pressure response to5
of ang i by5
is a type i5
and high concentrations of5
epidemiology of novel coronavirus5
and collectrin differentially interact5
system blockade on renal5
the role of ras5
as well as to5
ii type receptor blockers5
the actions of the5
of ang ii receptors5
vascular remodeling and pah5
and adam cleave ace5
the presence of at5
to contribute to the5
the expression of angiotensin5
due in part to5
converting enzyme determines plasma5
food and drug administration5
of patients with hypertension5
ace in the renal5
of ace by the5
it is interesting to5
increases in plasma ang5
heart weight to body5
protein of amino acids5
nitric oxide synthase activation5
use of ace inhibitors5
of expression of the5
ang iv and ang5
of at receptor blockade5
identification of a novel5
infusion of ang ii5
in experimental biliary fibrosis5
increased in patients with5
loss of ace in5
expression of angiotensin converting5
is available to authorized5
microbial ecology and intestinal5
cells and is detected5
the activity of ace5
to the pathogenesis of5
blockers and the risk5
supplementary figure s a5
has been observed in5
in severe pneumonia patients5
increased the expression of5
a h n infections5
with hypertension and diabetes5
the nucleus of the5
sodium and water reabsorption5
of pulmonary arterial hypertension5
and mortality in patients5
pressor and drinking responses5
the online version of5
of the human renin5
of ang peptide formation5
cell subsets across tissues5
was considered statistically significant5
implications for virus origins5
levels in experimental biliary5
the interaction of the5
type diabetes and nephropathy5
the ace gene is5
the beneficial effect of5
treatment with ace inhibitors5
carboxypeptidase from the hyperthermophilic5
neutral amino acid transporter5
in the present work5
and neprilysin in a5
which was blocked by5
the ratio of ang5
of the immune system5
via the at r5
mediated pressor and drinking5
hypertension and heart failure5
induced by avian influenza5
feb did not affect5
in the heart was5
receptor is the enzyme5
our results showed that5
consistent with our previous5
determines plasma clearance of5
similar to that of5
the cleavage of the5
arm of the renin5
infected pneumonia in wuhan5
differentially interact with hartnup5
from ang i by5
the conformational preferences of5
is a negative regulator5
increased expression of ace5
in patients with pulmonary5
glomerular localization and expression5
from lethal avian influenza5
on an acei or5
renin angiotensin system and5
that the actions of5
rats reduces blood pressure5
version of this article5
myocardial ischemia reperfusion angiotensin5
of ang i into5
reduction of blood pressure5
of protein kinase c5
balance between the two5
and angiotensin ii type5
ace is highly expressed5
the ace ace ratio5
to the apical surface5
cells were treated for5
the late development of5
severity of the disease5
smooth muscle cells and5
ace inhibitor and arb5
the spike proteins of5
of a role for5
did not differ between5
expressed as median and5
circulating activities of angiotensin5
high concentrations of resveratrol5
the leading cause of5
play a crucial role5
of ang ii are5
in vitro studies have5
and angiotensin receptor type5
with ang ii infusion5
viral invasion of host5
c a and c5
an upregulation of ace5
of the alternative raas5
remodeling and pah in5
other components of the5
confers cardiopulmonary protection against5
recent advances in the5
a novel target for5
role of ang ii5
amino acid transporter partners5
control of heart rate5
and caudal ventrolateral medulla5
tissue and lung tumor5
effects of the ras5
of the angiotensin converting5
inhibitors and risk of5
in the prevention of5
in transgenic mice with5
generation of reactive oxygen5
at the cell surface5
little is known about5
epithelial cells and is5
is a novel homolog5
at increased risk for5
to ang ii and5
reduces the progression of5
the rostral and caudal5
novel homolog of ace5
hypertrophy and fibrosis in5
available to authorized users5
synthesized a series of5
a vital role in5
the end of the5
are responsible for the5
a protective role of5
in the pe group5
detected in specific cell5
angiotensin system and the5
are at higher risk5
of cardiac hypertrophy induced5
the severity of covid5
is associated with susceptibility5
control of blood pressure5
diagnosis and treatment of5
functional expression of the5
roles of angiotensin peptides5
between ahf patients and5
the american college of5
is detected in specific5
between ang ii and5
that inhibition of the5
hypertensive rats angiotensin ii5
events in patients with5
gene in human airway5
death in patients with5
ace and ace expression5
the balance of the5
plays a significant role5
and is detected in5
ace is an interferon5
c domain of sace5
at concentrations of and5
inflammatory effects of the5
receptor and regulator of5
bovine aortic endothelial cells5
of angiotensin ii on5
the prevention of pulmonary5
ace and is developmentally5
a novel homolog of5
ras in the gastrointestinal5
and the pathogenesis of5
of the target protein5
fold higher than that5
reduce the production of5
ahf patients and the5
function in isolated perfused5
of the sodium pump5
urinary excretion of ang5
by the fact that5
the brain impairs baroreflex5
mrna and protein in5
amino acid transporter b5
and congestive heart failure5
antihypertensive actions of angiotensin5
this study is to5
of ang ii was5
impairs baroreflex function in5
we were able to5
activity in the brain5
the reduction in ace5
ace links amino acid5
left ventricular hypertrophy in5
bradykinin peptides in rats5
ii type receptor stimulation5
downregulation of ace and5
the reninangiotensin system in5
virus origins and receptor5
in serum of the5
study has shown that5
the physiological effects of5
to ang ii group5
in the development and5
interact with hartnup mutations5
ace is located on5
vessels of shrsp rats5
adam cleave ace differentially5
involvement of the ras5
expressed on the surface5
to be one of5
in increased ang ii5
receptor ace is an5
is not yet known5
the activation of nf5
the contribution of the5
and was associated with5
processing of angiotensin peptides5
different from control group5
human ace in heart5
mediated ace shedding in5
reactive oxygen species in5
ii from ang i5
demonstrated that ang ii5
for a role of5
of the two active5
a significant decrease in5
blockade on renal angiotensin5
of the ace inhibitor5
can lead to a5
shrsp rats reduces blood5
of ace has been5
were the first to5
and risk of cancer5
also known as insulin5
angiotensin ii receptors and5
of patients with coronavirus5
the at and at5
amino acids from the5
and weeks of gestation5
of the physiological and5
van kats et al5
links amino acid malnutrition5
in order to evaluate5
tmprss and adam cleave5
omapatrilat and enalapril in5
isolated perfused rat hearts5
and transforming growth factor5
and improves endothelial function5
the expression level of5
and the at receptor5
acid transporter b at5
angiotensin receptor blockers on5
large body of evidence5
might be related to5
in an effort to5
of myocardial infarction in5
urinary levels of ang5
role of ace and5
significantly different from ang5
ace is associated with5
differences in the expression5
the cells were incubated5
that ace is a5
of ang ii synthesis5
ang tie system is5
in the united states5
inflammatory cytokines such as5
mechanisms of angiotensin ii5
a key role of5
captopril on mortality and5
ace in patients with5
the induction of mir5
ace is a type5
compared with wt mice5
in the lcz group5
were purchased from the5
neprilysin in a family5
the innate immune response5
reactive oxygen species and5
ii levels in the5
spontaneously hypertensive rats angiotensin5
of ace inhibitors or5
the glomerular filtration barrier5
is expressed on the5
online version of this5
homolog of ace and5
play an essential role5
been found in the5
ace is a zinc5
angiotensin receptor blockers and5
the reason for the5
the cardioprotective effects of5
peptidase in the renin5
of ang ii effects5
and function of the5
treatment of cells with5
with a reduction in5
evidence that the angiotensin5
mrna and protein levels5
level of expression of5
the binding of ang5
expression in human heart5
of angiotensin ii with5
ali or ards induced5
deletion of the at5
ang ii did not5
for severe acute respiratory5
of these drugs in5
through the at receptor5
have not yet been5
in the face of5
our aim was to5
the protective effect of5
in the kidney and5
in the proximal tubule5
we report the synthesis5
against lung fibrosis and5
and biological activity of5
different from ang ii5
in the brain impairs5
in db db mice5
cells were grown in5
that the angiotensin iv5
in the acute phase5
cardiac dysfunction and pathological5
catalyzes the conversion of5
responses to ang ii5
rostral and caudal ventrolateral5
of aceis and arbs5
significantly different from control5
on the expression of5
ang ii ang i5
leads to the late5
baroreflex function in hypertensive5
of ace leads to5
shed light on the5
converting enzyme insertion deletion5
partners ace and collectrin5
lethal avian influenza a5
been shown to exert5
the isolated perfused rat5
of vascular smooth muscle5
to be effective in5
with reduced ejection fraction5
associated with acute respiratory5
role of sfrp in5
is then cleaved by5
in isolated perfused rat5
cigarette smoke for months5
the cardiovascular effects of5
ace inhibitor or arb5
was significantly decreased in5
deletion polymorphism is associated5
prone spontaneously hypertensive rats5
of ace on the5
of at r by5
ace is also the5
agonist of the mas5
terminal catalytic domain of5
enzyme inhibitors angiotensin receptor5
the emerging role of5
increase the levels of5
data are expressed as5
binding of ang ii5
to the mineralocorticoid receptor5
probably due to the5
ace is expressed on5
ace in the context5
and its effect on5
the existence of an5
bradykinin peptide levels in5
we also showed that5
transducer and activator of5
with the aim of5
enzyme protects from lethal5
the ang ii receptor5
is mainly expressed in5
collectrin differentially interact with5
coupled receptor mas angiotensin5
protocol was approved by5
of shrsp rats reduces5
which has been shown5
all values are mean5
both ang i and5
a part of the5
the function of the5
in blood pressure in5
blood pressure and improves5
the heart and the5
studies have reported that5
the regulation of ace5
c cells were treated5
mice with ang ii5
the recognition of sars5
mrna expression in the5
has not been reported5
has also been reported5
study was supported by5
acute lung failure the5
mediated reduction of angiotensin5
be responsible for the5
expressed in the heart5
ii type receptor antagonist5
and is developmentally regulated5
in specific cell subsets5
the development of an5
with the fact that5
did not have any5
plays a central role5
the ras in lung5
in severe acute respiratory5
for the production of5
reduction in blood pressure5
through the mas receptor5
we would like to5
inhibitors angiotensin receptor blockers5
of oxidative stress and5
was added to the5
associated with increased ace5
has emerged as a5
developmentally regulated in embryonic5
a variety of tissues5
of the ras system5
the plasma level of5
ace and collectrin differentially5
identical to the c5
in which cells were5
approval of the version5
to the presence of5
used in this study5
have proven to be5
at a and at5
and protein expression levels5
seen in patients with5
the use of the5
localization and expression of5
peptides and recombinant human5
associated with a reduction5
of ace inhibition on5
to be present in5
its effect on the5
been shown to inhibit5
the discovery of a5
by severe acute respiratory5
be considered as a5
were treated for h5
hyperthermophilic archaeon pyrococcus furiosus5
of acei and arbs5
in cardiovascular and renal5
contribute to the formation5
on blood pressure and5
ace inhibitor therapy in5
middle cerebral artery occlusion5
the metabolism of ang5
the pathophysiology of covid5
and the development of5
type angiotensin ii receptor5
binding to the mas5
terminal active site of5
cells in patients with5
can be cleaved by5
by ang ii in5
the significance of this5
metabolism in pulmonary and5
we found that ang5
in the rat kidney5
angiotensin system in human5
ace mrna and protein5
cardiac angiotensin converting enzyme5
apelin antagonizes ang ii5
origins and receptor binding5
understanding of the renin5
specific amino acid transporter5
signal transducer and activator5
activity correlated inversely with5
an important component of5
in our previous study5
been shown to reduce5
with the progression of5
in this review we5
to further investigate the5
acid malnutrition to microbial5
of the discovery of5
at and months after5
have been made to5
the production of the5
axis confers cardiopulmonary protection5
inhibiting the formation of5
in human and experimental5
of ang ii as5
losartan compared with captopril4
the animal care and4
by the ace ang4
vasodilator action of angiotensin4
induce the upregulation of4
of heart injury among4
increased expression of angiotensin4
urine of normal and4
subtype in the aorta4
coronavirus and human coronavirus4
with symptomatic heart failure4
patients and healthy controls4
respiratory syndrome coronavirus and4
as shown by the4
the active sites of4
stimulated arachidonic acid release4
potential mechanism of heart4
enzyme type attenuates neurogenic4
enzyme responsible for ang4
with a decrease in4
specific substrate and c4
in contrast to ace4
was no significant difference4
the urine of normal4
on cardiovascular events in4
mediates endothelial nitric oxide4
the hemoregulatory peptide n4
jurisdictional claims in published4
insensitive to ace inhibitors4
is widely expressed in4
to investigate the effect4
the presence of ang4
detection of soluble angiotensin4
in patients with sars4
endogenous ang ii antagonism4
accumulating evidence suggests that4
the design and synthesis4
levels of plasma ang4
mas pathway in the4
fatal outcomes of patients4
of ace is associated4
administration of recombinant human4
in response to myocardial4
on the synthesis of4
cleaved by ace to4
oxide synthase activation via4
in cardiovascular physiology and4
of angiotensin i converting4
was isolated using trizol4
effects of at receptor4
of diabetic nephropathy in4
ace in the lung4
of a report of4
system in cardiovascular disease4
enzyme in heart failure4
of ace inhibitors in4
the first study to4
peptide levels in mice4
differentiation of human airway4
classical raas axis activation4
cardiac fibroblasts to initiate4
a report of cases4
blood pressure elevation and4
showed that circulating ace4
with regard to jurisdictional4
carried out using the4
shown to be present4
cells is mediated by4
the pathogenesis of podocyte4
structural studies of sars4
a high concentration of4
proxy measure of ace4
of nitric oxide by4
kinases in proximal tubular4
amino acid sequence of4
outcomes in h n4
human blood vessel organoids4
our results suggested that4
was found that the4
increased in ang ii4
studies indicate that the4
induced by myocardial infarction4
increase of the metabolite4
ace via the at4
injury in mice by4
inflammatory effects of ace4
treatment of heart failure4
mediate the antihypertensive actions4
have been reported to4
and clinical characteristics of4
umbilical vein endothelial cells4
the context of the4
b protein expression by4
and human coronavirus nl4
new roles in inflammation4
and the mechanism of4
in patients with vasodilatory4
effect of reduced angiotensin4
catalytic domain of ace4
role of the at4
ang ii have been4
has yet to be4
active site of human4
in the presence or4
angiotensin ii at receptors4
patients with symptomatic heart4
protective but downregulated in4
antifibrotic and antitrophic effects4
of nitric oxide and4
in an in vitro4
when compared with the4
a regulatory role in4
levels of angiotensin ii4
hope and europa studies4
r and b r4
blood pressure regulation and4
the juxtaglomerular cells of4
with the use of4
a decoy peptide corresponding4
heart disease and heart4
cell proliferation and ace4
bars indicate the mean4
difference of ace expression4
isolated from the venom4
and ang ii are4
the length of the4
ace is found in4
their ability to inhibit4
prevents the angiotensin ii4
the active site cleft4
blockers of the renin4
of the raas are4
leading to a reduction4
expression and regulation of4
produces cardioprotective effects in4
involvement of ace in4
ace deficiency is associated4
in diabetic angiotensin ii4
skeletal muscle and lungs4
injury induced by respiratory4
is a key factor4
in the rostral and4
receptor de ang ii4
a large family of4
modulator of the human4
by at least two4
actions of angiotensin ii4
in order to develop4
the permeability of the4
human umbilical cord blood4
and circulating levels of4
of losartan compared with4
angiotensin converting enzyme angiotensin4
amino acids and the4
and coronary heart disease4
published maps and institutional4
beneficial effects of at4
in systolic blood pressure4
acid release and prostanoid4
are also known to4
on isolated rabbit afferent4
mainly expressed in the4
ace shedding in neurogenic4
the basis for the4
exposed to fresh air4
no significant difference in4
effect of losartan compared4
were no differences in4
induced cellular hypertrophy through4
plasma renin activity and4
ace may serve as4
the value of the4
ras have been identified4
a downregulation of ace4
enzyme inhibits lung injury4
are patients with hypertension4
a proxy measure of4
of the local ras4
we have investigated the4
to be expressed in4
to the activation of4
production of angiotensin ii4
role for collectrin in4
with mild or severe4
blockade inhibits development of4
stimulation of the sympathetic4
activity of the ace4
play a significant role4
cells with ang ii4
celebrating the th anniversary4
either ang i or4
heart failure survival study4
the degradation of the4
type shedding contributes to4
by ace inhibitors and4
by reducing oxidative stress4
slowing the progression of4
amino acid sequences of4
mice were subjected to4
in serum of severe4
localized to the apical4
characterization of renal angiotensin4
increased the metabolite formation4
vasopeptidase to sars virus4
shown to reduce the4
p map kinase pathway4
physiological function of ace4
likely contributes to the4
ace inhibition may be4
cytokines such as tnf4
is a biologically active4
the final approval of4
there is evidence that4
antithrombotic effect of angiotensin4
by mass spectrometry and4
used to study the4
increase the risk of4
for ang ii and4
dysfunction in myocardial infarcted4
for the existence of4
expression of ace is4
subfornical organ prevents the4
even in the absence4
via angiotensin ii type4
nephropathy by a decoy4
was able to significantly4
in hyperoxic lung injury4
of death in patients4