bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
stem cell	2650
cell transplantation	1933
bone marrow	1275
transplant recipients	1111
hematopoietic stem	1068
mg kg	995
peripheral blood	858
median age	790
overall survival	747
acute gvhd	690
chronic gvhd	689
patients received	665
conditioning regimen	642
host disease	614
cd cd	605
risk factors	585
median follow	582
cd cells	573
allogeneic hematopoietic	512
stem cells	511
median time	487
free survival	478
cmv infection	472
one patient	464
nk cells	441
allogeneic stem	434
flow cytometry	426
high risk	425
breast milk	400
cord blood	394
gvhd prophylaxis	392
cmv reactivation	389
cell transplant	368
cumulative incidence	360
viral infections	347
immune response	336
marrow transplantation	330
allogeneic hsct	328
solid organ	326
graft failure	324
unrelated donor	319
lung transplant	316
mg dl	313
complete remission	299
viral load	297
two patients	288
significantly higher	284
multivariate analysis	284
ng ml	270
patients receiving	263
related mortality	261
blood stem	260
transplant patients	251
virus infection	248
graft versus	248
intensity conditioning	247
lung transplantation	244
grade ii	243
myeloablative conditioning	242
immune reconstitution	242
immune system	239
renal transplant	239
respiratory tract	238
reduced intensity	236
hematopoietic cell	235
organ transplant	235
matched unrelated	228
versus host	225
multiple myeloma	224
infectious diseases	223
increased risk	222
patients undergoing	221
cd cell	221
unrelated donors	219
cmv disease	215
relapse mortality	213
myeloid leukemia	212
risk factor	212
acute myeloid	212
significant difference	211
conditioning regimens	208
fungal infections	204
autologous stem	201
organ transplantation	200
infectious complications	200
primary immunodeficiency	198
kg day	197
cell lines	197
statistically significant	197
adult patients	194
grade iii	193
dendritic cells	192
donor chimerism	190
introduction background	190
immune responses	187
acute leukemia	186
barr virus	186
adverse events	183
side effects	183
hsct recipients	182
cell source	182
mycophenolate mofetil	178
herpes simplex	178
patients without	178
hemorrhagic cystitis	177
nk cell	177
ex vivo	177
three patients	177
intensive care	176
liver transplantation	176
renal failure	176
patients treated	176
retrospective study	175
graft survival	174
united states	174
acute graft	173
months post	172
time pcr	171
control group	171
patients developed	171
years old	170
acute rejection	170
marrow transplant	169
class i	169
year os	164
ist die	162
four patients	162
cell receptor	161
two groups	161
immunocompromised patients	160
bei der	158
patients died	158
significantly lower	157
pediatric patients	156
viral infection	156
cell depletion	155
cytomegalovirus infection	152
disease status	152
clinical trial	152
hiv infection	152
clinical trials	152
patients transplanted	152
university hospital	151
renal function	151
high dose	151
cell count	150
gene expression	150
specific cd	148
immune deficiency	147
cd ra	147
human immunodeficiency	146
cmv dna	144
copies ml	143
immunodeficiency virus	143
five patients	142
present study	142
mononuclear cells	142
long term	141
cell responses	140
cell activation	139
acute respiratory	139
significant differences	139
cell lymphoma	138
cell proliferation	138
post transplant	138
kidney transplant	137
median number	137
bacterial infections	136
may also	136
heart transplant	135
neutrophil engraftment	134
matched sibling	134
matched related	134
data suggest	134
renal transplantation	132
infected patients	132
respiratory syncytial	132
simplex virus	132
well tolerated	131
sibling donor	131
cell dose	131
pg ml	131
acute lymphoblastic	130
syncytial virus	129
haematopoietic stem	129
patienten mit	128
epithelial cells	128
first year	127
transplant recipient	127
prospective study	127
opportunistic infections	126
platelet engraftment	126
risk patients	126
consecutive patients	125
iu ml	125
severe acute	124
retrospective analysis	124
univariate analysis	124
days post	124
mortality rate	124
single center	123
chain reaction	123
aml patients	121
invasive fungal	121
graft function	120
graft rejection	120
liver transplant	120
monoclonal antibodies	120
allogeneic sct	120
one year	119
monoclonal antibody	118
lymphoblastic leukemia	118
polymerase chain	118
umbilical cord	118
bk virus	118
healthy controls	118
cells kg	118
hematological malignancies	117
care unit	117
aplastic anemia	117
healthy donors	117
body irradiation	116
immunosuppressive therapy	115
kidney transplantation	115
pts received	114
fi rst	113
chronic graft	113
performed using	113
mixed chimerism	112
related donor	111
replacement therapy	111
zoster virus	111
en el	111
combined immunodeficiency	111
year overall	110
antiviral therapy	109
disease progression	109
identical sibling	109
human herpesvirus	109
dose chemotherapy	108
hodgkin lymphoma	108
mean age	108
total body	107
zu einer	107
induction therapy	107
iv acute	106
cell subsets	106
hsct patients	106
important role	106
cell therapy	106
time points	106
mit einer	106
mechanical ventilation	105
among patients	105
hematologic malignancies	105
results suggest	105
cell counts	104
staphylococcus aureus	104
transplant related	103
allogeneic hct	103
previously reported	103
nkt cells	103
study group	103
virus infections	103
least one	103
grade i	103
high levels	102
fungal infection	102
relapse rate	102
progressive disease	101
liver disease	101
patients underwent	101
nervous system	101
haploidentical donor	100
first months	100
natural killer	100
age years	100
cmv pneumonia	100
lower respiratory	100
significantly increased	100
patient died	99
cell surface	99
six patients	99
blood samples	98
mhc class	98
cord uid	98
first days	98
doc id	98
invasive aspergillosis	98
retrospectively analyzed	98
respiratory viruses	97
response rate	97
donor type	97
kommt es	97
clinical manifestations	97
vor allem	97
relapse incidence	95
lymph nodes	95
antiretroviral therapy	95
survival rates	95
central nervous	95
residual disease	95
significantly associated	94
patient developed	94
complete response	94
last follow	94
line therapy	94
inkt cells	93
infected cells	92
mm patients	92
exome sequencing	92
survival rate	92
autologous hsct	92
partial response	92
significantly reduced	92
higher risk	91
seven patients	90
ist eine	90
cell function	90
disease relapse	90
autoimmune diseases	90
antithymocyte globulin	90
allogeneic transplantation	89
based conditioning	89
myelodysplastic syndrome	89
chronic rejection	89
eight patients	89
full donor	89
cell line	88
disease control	88
lung disease	88
und die	88
graft loss	87
cytokine production	87
body weight	87
von der	87
human cytomegalovirus	87
cell depleted	86
immune suppression	85
severe combined	85
signifi cant	85
durch die	85
term survival	84
allograft rejection	84
low dose	84
heart transplantation	84
preemptive therapy	84
active disease	84
west nile	84
may occur	84
median duration	83
antifungal prophylaxis	83
day post	83
yellow fever	83
gvhd grade	83
transplanted patients	82
intravenous immunoglobulin	82
calcineurin inhibitors	82
abdominal pain	82
ml min	81
virus type	81
median cd	81
medical center	81
type i	81
significantly different	81
immune dysregulation	80
die diagnose	80
previous studies	80
und der	80
blood cells	80
whole blood	80
respiratory distress	80
prophylaxis consisted	79
primary infection	79
cell development	79
wild type	79
patients showed	79
bronchiolitis obliterans	79
transplant cyclophosphamide	79
bis zu	79
recurrent infections	78
within days	78
immune globulin	78
cell death	78
significant increase	78
case report	78
donor lymphocyte	78
endothelial cells	78
tract infections	78
acute renal	78
pneumocystis carinii	77
partial remission	77
first time	77
innate immune	77
clinical outcomes	77
treatment option	77
none declared	77
presenting cells	77
allogeneic bone	77
clinical features	77
immune repertoire	76
hct recipients	76
patients aged	75
cell culture	75
underlying disease	75
general population	75
septic shock	75
urinary tract	75
nachweis von	75
class ii	75
old male	75
nucleic acid	75
poor prognosis	74
cytomegalovirus disease	74
salvage therapy	74
relapsed refractory	74
nine patients	74
donor age	74
lymphoproliferative disorder	74
underwent allogeneic	74
ebv infection	73
statistical analysis	73
ebv reactivation	73
herpes zoster	73
patients achieved	73
health care	73
mouse model	73
hla matched	73
died due	73
gastrointestinal tract	73
cell response	73
clinical practice	73
bronchoalveolar lavage	73
cd count	73
deficient mice	73
hiv patients	72
lymphocyte count	72
analysis showed	72
platelet count	72
autologous hematopoietic	72
patients presented	72
nile virus	72
occlusive disease	72
serum creatinine	72
haploidentical transplantation	72
patient survival	71
related donors	71
thymocyte globulin	71
term follow	71
clinical presentation	71
renal disease	71
clinical outcome	71
mg day	71
marrow failure	71
amino acid	70
mit der	70
curative treatment	70
hemorrhagic fever	70
adenovirus infection	70
year survival	70
sos vod	70
hla identical	70
undergoing allogeneic	69
logistic regression	69
disease free	69
electron microscopy	69
minimal residual	69
declare background	69
line treatment	69
signifi cantly	69
higher incidence	69
whole exome	69
high mortality	69
early post	68
mismatched unrelated	68
post hsct	68
critically ill	68
bei kindern	68
blood mononuclear	68
infectious disease	68
respiratory failure	68
renal allograft	68
transcription factor	68
upper respiratory	68
supportive care	68
major cause	67
th cells	67
mit dem	67
autosomal recessive	67
specific antibodies	67
included patients	67
underwent hsct	67
extensive chronic	67
antifungal therapy	67
progenitor cells	67
patient population	67
lymphoproliferative disease	67
neutrophil recovery	66
effector cells	66
cell reconstitution	66
los pacientes	66
randomized trial	66
mit einem	66
data indicate	66
commonly used	66
cmv viremia	66
following allogeneic	66
neutropenic patients	66
organ failure	65
clinical course	65
phase i	65
protein expression	65
primary endpoint	65
treated patients	65
adoptive transfer	65
significant reduction	65
respiratory syndrome	65
phase ii	65
determine whether	64
recent years	64
statistical significance	64
within months	64
liver failure	64
quantitative pcr	64
previously described	64
immunoglobulin replacement	64
may lead	64
twice daily	64
prospective studies	64
cell lymphopenia	64
der regel	63
sibling donors	63
viral loads	63
year old	63
graft source	63
early diagnosis	63
young children	63
cohort study	62
transplant centers	62
lymphocyte counts	62
blood transplantation	62
kg kg	62
serum levels	62
cmv pcr	62
gene therapy	62
cells ul	62
primary immune	62
risk group	62
one case	62
cells showed	62
adaptive immune	62
lymph node	61
transplant period	61
risk score	61
atg group	61
prognostic factors	61
parainfluenza virus	61
factors associated	61
haploidentical hsct	61
immune status	61
genetic testing	61
median os	61
cvid patients	61
necrosis factor	61
influenza virus	61
mg ml	61
patient received	61
related complications	61
granulomatous disease	61
maintenance therapy	61
viral reactivation	61
expressed breast	61
results demonstrate	60
antigen presenting	60
blood cell	60
informed consent	60
patients engrafted	60
may contribute	60
en los	60
high rate	60
patients experienced	60
auf die	60
breast cancer	60
fludarabine mg	60
myeloma patients	60
common variable	59
patients may	59
cells expressing	59
cd expression	59
severe disease	59
red blood	59
case reports	59
high incidence	59
antibody response	59
plasma cells	59
advanced disease	59
tract infection	59
center experience	59
antimicrobial therapy	59
diabetes mellitus	59
haploidentical donors	58
medical records	58
cell types	58
first line	58
antiviral treatment	58
weight loss	58
western blot	58
mast cells	58
highly active	58
tumor cells	58
human milk	58
clinical data	58
inflammatory response	58
cox regression	58
varicella zoster	58
controlled trial	58
cd foxp	57
malignant disease	57
shock syndrome	57
lymphocyte subsets	57
bal fluid	57
significantly better	57
term outcome	57
modern hopfield	57
hazard ratio	57
toxic shock	57
surface expression	57
low risk	57
alternative donor	57
may help	56
effective treatment	56
human metapneumovirus	56
viral replication	56
matched donor	56
old female	56
cell numbers	56
chronic granulomatous	56
carinii pneumonia	56
common cause	56
cell population	56
bei patienten	56
year post	56
positive cells	56
undergoing hsct	56
cells mm	55
may result	55
adverse effects	55
per day	55
antigen presentation	55
flow cytometric	55
pcr assay	55
zu den	55
bacterial infection	55
also observed	55
mycobacterium tuberculosis	55
working party	55
generation sequencing	55
developed acute	55
specific antibody	55
respiratory virus	54
data show	54
platelet recovery	54
attention mechanism	54
quantitative real	54
clinically significant	54
lymphoproliferative disorders	54
trend towards	54
i ii	54
therapeutic option	54
median day	54
analysis revealed	54
haploidentical stem	54
progression free	54
inflammatory cytokines	54
sind die	54
lymphoma patients	54
elderly patients	53
time period	53
extracorporeal photopheresis	53
pneumocystis jirovecii	53
ill patients	53
immunodefi ciency	53
remaining patients	53
median days	53
following hsct	53
allograft survival	53
herpes virus	53
cell populations	53
iv agvhd	53
primary immunodeficiencies	53
two years	53
posttransplant lymphoproliferative	53
treatment options	53
treatment related	52
die therapie	52
pseudomonas aeruginosa	52
ist der	52
patients suffering	52
distress syndrome	52
underwent allo	52
study period	52
developed grade	52
successfully treated	52
mesenchymal stem	52
allogeneic haematopoietic	52
disseminated disease	52
sickle cell	52
primary graft	52
icu admission	52
significant risk	52
autologous transplantation	51
aber auch	51
se ha	51
immune cells	51
preliminary results	51
auch bei	51
blood cultures	51
adoptive immunotherapy	51
see table	51
skin lesions	51
family members	51
innate immunity	51
inflammatory bowel	51
refractory acute	51
clinical characteristics	51
newborn screening	51
variable immunodeficiency	51
multicenter study	51
one month	50
newly diagnosed	50
kg tag	50
el trasplante	50
ric allo	50
may cause	50
respiratory infections	50
severe chronic	50
trial registry	50
stimulating factor	50
first month	50
infection may	50
dependent manner	50
older patients	50
blood products	50
vg vd	50
cystic fibrosis	50
neutrophil count	50
cmv infections	50
clinical symptoms	50
growth factor	50
refractory disease	50
hcv infection	50
leaf curl	50
repertoire classification	50
overall response	50
hemolytic anemia	49
severe cgvhd	49
independent risk	49
antibiotic therapy	49
patients diagnosed	49
family donor	49
widely used	49
por cmv	49
machine learning	49
two different	49
tumor necrosis	49
cd ro	49
year cumulative	49
transplant outcomes	49
clinical response	49
thrombotic microangiopathy	49
predictive value	49
hopfield networks	49
significantly decreased	49
dengue virus	49
post transplantation	48
patients relapsed	48
recent studies	48
pneumocystis jiroveci	48
bl mice	48
neutropenic fever	48
el tratamiento	48
otitis media	48
results show	48
overall mortality	48
bowel disease	48
last years	48
mediated rejection	48
wird durch	48
cell mobilization	48
cyclophosphamide mg	48
high level	48
pts died	48
ten patients	48
cell replete	48
years post	48
serum samples	48
solid tumors	47
drug interactions	47
haploidentical transplant	47
durch den	47
results indicate	47
salvage treatment	47
male patients	47
hiv transmission	47
vertical transmission	47
second line	47
acquired pneumonia	47
agvhd grade	47
cik cells	47
one patients	47
immune cell	47
autologous sct	47
inclusion criteria	46
der nachweis	46
recipient age	46
febrile neutropenia	46
severe gvhd	46
current study	46
grade iv	46
positive patients	46
achieved cr	46
melphalan mg	46
differential diagnosis	46
en pacientes	46
gi tract	46
significant morbidity	46
auf eine	46
secondary graft	46
amino acids	46
human cd	46
received hsct	46
dna load	46
independently associated	46
multiple sclerosis	46
transplant lymphoproliferative	46
nach der	46
leukemia patients	46
family history	46
second transplant	46
antibody deficiency	45
retrospectively reviewed	45
cell cycle	45
obliterans syndrome	45
total number	45
immunosuppressive regimen	45
response rates	45
hla class	45
active antiretroviral	45
cytomegalovirus reactivation	45
respiratory viral	45
antibiotic treatment	45
chronic allograft	45
cell transplants	45
large number	45
cmv promoter	45
adenovirus infections	45
copy number	45
white blood	45
cmv seropositive	45
kg cd	45
real time	45
central venous	45
human herpes	45
allograft recipients	45
severe cases	45
two cases	44
allogeneic transplant	44
regression analysis	44
haematological malignancies	44
severe infections	44
gabe von	44
different time	44
low cd	44
autoimmune disease	44
renal impairment	44
escherichia coli	44
mortality rates	44
influenza vaccine	44
und eine	44
i molecules	44
intravenous ganciclovir	44
cells may	44
cytokine release	44
negative bacteria	44
patient age	44
unrelated cord	44
malignant diseases	43
pulmonary disease	43
apoptotic cells	43
calcineurin inhibitor	43
graft dysfunction	43
cell differentiation	43
mononuclear cell	43
cd depleted	43
donor cells	43
pulmonary infections	43
findings suggest	43
bacterial pneumonia	43
confidence interval	43
diffuse large	43
received myeloablative	43
tyrosine kinase	43
obstruction syndrome	43
effector memory	43
mrna expression	43
nephrotic syndrome	43
expression levels	43
systematic review	43
chart review	43
improved survival	43
multiorgan failure	42
immunosuppressed patients	42
dna polymerase	42
disclosure background	42
chronic hepatitis	42
bu cy	42
curative option	42
fold increase	42
immunosuppressive agents	42
increased mortality	42
ist ein	42
es zu	42
emptive therapy	42
protective effect	42
performance status	42
preparative regimen	42
case series	42
secondary prophylaxis	42
premature infants	42
rank test	42
cd kg	42
specific immune	42
mediated immunity	42
median survival	41
dendritic cell	41
vod sos	41
regimen consisted	41
igg levels	41
remains unclear	41
late effects	41
per year	41
lymphocyte infusions	41
safety profile	41
therapie der	41
aids patients	41
pregnant women	41
combination therapy	41
well known	41
eleven patients	41
cmv pneumonitis	41
risk aml	41
research funding	41
myeloid leukaemia	41
lupus erythematosus	41
cmv retinitis	41
cell disease	41
donor source	41
para el	41
regression model	41
hemophagocytic lymphohistiocytosis	41
gvhd occurred	41
months later	41
lymphocyte infusion	41
plasma levels	40
physical examination	40
infl ammatory	40
transplant outcome	40
hematopoietic cells	40
stable disease	40
survival benefit	40
streptococcus pneumoniae	40
von einer	40
immunocompetent patients	40
via breast	40
relapse risk	40
associated nephropathy	40
renal dysfunction	40
liposomal amphotericin	40
diagnostic criteria	40
waiting list	40
lower incidence	40
donor cell	40
patient characteristics	40
risk acute	40
successful treatment	40
effi cacy	40
finden sich	40
cancer patients	40
mouse models	40
phase study	40
may provide	40
auch die	40
three months	40
antiviral prophylaxis	40
term outcomes	40
cell infusion	40
patients compared	39
risk cytogenetics	39
normal range	39
cd lymphocytes	39
nicht bekannt	39
clostridium difficile	39
im rahmen	39
oral valganciclovir	39
fluid specimens	39
important cause	39
systemic lupus	39
underwent asct	39
chronic myeloid	39
increased expression	39
potentially curative	39
signal transduction	39
enfermedad por	39
may play	39
rsv infection	39
year period	39
mg twice	39
treated mice	39
immune recovery	39
invasive disease	39
transplant candidates	39
also found	39
infectious mononucleosis	39
antibody titers	39
median dose	39
lung biopsy	39
der patienten	39
preliminary data	39
humoral immunity	38
kidney disease	38
pid patients	38
ist das	38
adaptive immunity	38
one hundred	38
natural history	38
infection control	38
elderly persons	38
situ hybridization	38
immunodeficiency syndrome	38
ctla ig	38
several studies	38
infektionen mit	38
significant impact	38
well established	38
blood pressure	38
group compared	38
per kg	38
infl uence	38
study included	38
primary human	38
severe aplastic	38
die inkubationszeit	38
immunosequencing data	38
nkt cell	38
ko mice	38
rejection episodes	38
nd allo	37
aus der	37
bei immunsupprimierten	37
prognostic factor	37
scid patients	37
resistant staphylococcus	37
renal involvement	37
target cells	37
growth factors	37
signaling pathways	37
mg daily	37
stromal cells	37
lung injury	37
adoptively transferred	37
toxoplasma gondii	37
younger patients	37
thalassemia major	37
cell repertoire	37
immunosuppressive treatment	37
received allo	37
cells infused	37
entire cohort	37
aspergillus fumigatus	37
airway pressure	37
received allogeneic	37
red cell	37
donor recipient	37
curative therapy	37
three times	37
fl uconazole	37
cmv prophylaxis	37
bei einer	37
standard treatment	37
defi ned	37
nach einer	37
small number	37
sinusoidal obstruction	37
following transplantation	37
hiv infected	37
main cause	37
antiviral agents	37
cell recovery	37
time point	37
older age	37
immunoglobulin levels	37
significant improvement	37
auf der	36
ric regimen	36
results showed	36
event free	36
patients affected	36
viral diseases	36
related toxicity	36
developed chronic	36
least months	36
vs days	36
nur bei	36
chez les	36
jazz pharmaceuticals	36
serious adverse	36
viral pathogens	36
treg cells	36
low levels	36
implanted signals	36
pcr assays	36
consecutive days	36
antimicrobial agents	36
bei den	36
cellular immune	36
per patient	36
colony stimulating	36
weight gain	36
aufgrund der	36
old boy	36
prospective randomized	36
higher levels	36
viral antigens	36
kidney function	36
patient group	36
patient presented	36
reperfusion injury	36
better os	36
next generation	36
taken together	36
viral pneumonia	36
induction chemotherapy	36
many patients	36
combined immune	36
producing cells	36
sample size	36
compound heterozygous	36
significant decrease	35
als auch	35
ist nicht	35
term survivors	35
aged years	35
phase iii	35
liver function	35
cumulative incidences	35
heart failure	35
ct scan	35
developed severe	35
interstitial pneumonia	35
icu stay	35
may represent	35
crucial role	35
cd positive	35
transgene expression	35
trough levels	35
plasmid dna	35
pts receiving	35
nach dem	35
breastfed infants	35
single dose	35
progressive multifocal	35
acquired immunodeficiency	35
antibody responses	35
severe sepsis	35
immunodeficiency diseases	35
two weeks	35
significantly improved	35
und bei	35
mds patients	35
kann eine	35
control groups	35
kann es	35
nucleated cells	35
public health	35
cmv viral	35
family donors	35
six months	35
poor outcome	34
hospital stay	34
animal models	34
less likely	34
relapse rates	34
pulmonary aspergillosis	34
cd bright	34
regulatory cells	34
within hours	34
invasive pulmonary	34
patients required	34
marrow cells	34
dna vaccine	34
often associated	34
surviving patients	34
first complete	34
data demonstrate	34
disease caused	34
disease risk	34
cell immunity	34
blood donors	34
behandelt werden	34
pulmonary infection	34
abstract already	34
zu einem	34
leading cause	34
effective therapy	34
tolerance induction	34
already published	34
cgvhd patients	34
low incidence	34
latent infection	34
patients included	34
cardiac transplantation	34
multivariate cox	34
candida species	34
five years	34
nonrelapse mortality	34
steroid refractory	34
cmv dataset	34
autologous transplant	34
patient cohort	34
analyzed using	34
engraftment occurred	34
analyzed patients	34
female patients	33
pediatric lung	33
wt mice	33
estos pacientes	33
mycoplasma pneumoniae	33
medical history	33
aus dem	33
fully matched	33
kg bw	33
acute phase	33
cells per	33
studies showed	33
cd counts	33
sowie die	33
showed significantly	33
cell leukemia	33
molecular mechanisms	33
university medical	33
type ii	33
higher mortality	33
national institute	33
higher rate	33
intermediate risk	33
transplant center	33
study population	33
high frequency	33
recent study	33
achieved complete	33
treatment failure	33
patients following	33
cd antibody	33
healthy individuals	33
key role	33
increased incidence	33
dock deficiency	33
um eine	33
ecp treatment	33
pleural effusion	33
salvage chemotherapy	33
lassen sich	33
research center	33
cerebrospinal fluid	33
similar results	33
every weeks	33
child transmission	33
like receptor	33
thrombocytopenic purpura	33
gibt es	33
clinical diagnosis	33
three groups	32
grid search	32
myeloid cells	32
authors declare	32
spectrum antibiotics	32
pilot study	32
short course	32
clinical improvement	32
mast cell	32
single cell	32
nitric oxide	32
clinical studies	32
median interval	32
even though	32
sinopulmonary infections	32
cell viability	32
seropositive patients	32
broad spectrum	32
igg level	32
world data	32
patient showed	32
serum igg	32
pulmonary complications	32
mehr als	32
standard therapy	32
input object	32
meld score	32
leukemic cells	32
meier method	32
candida albicans	32
infectious agents	32
chimeric antigen	32
without evidence	32
selected patients	32
bloodstream infections	32
lung function	32
critical role	32
still alive	32
longer follow	32
kidney recipients	32
deficient patients	32
based regimen	32
female donor	32
transplantation recipients	32
immunocompromised hosts	32
like receptors	32
cardiac allograft	32
giant cells	32
hcv rna	32
randomized controlled	32
peripheral stem	32
progenitor cell	32
bk nephropathy	32
limited data	31
mycobacterium avium	31
nod card	31
wegen der	31
therapie mit	31
ist bei	31
infections may	31
specific cytotoxic	31
nach transplantation	31
soft tissue	31
identifi ed	31
large cohort	31
der hiv	31
binding site	31
center study	31
cell products	31
mean time	31
first day	31
haploidentical hematopoietic	31
severe infection	31
cell infiltration	31
organ dysfunction	31
es sich	31
studies suggest	31
dna repair	31
antigen receptor	31
computed tomography	31
age groups	31
controlled trials	31
infektionen durch	31
sct recipients	31
using flow	31
may improve	31
clinical background	31
primary prophylaxis	31
nkg dl	31
transgenic mice	31
united kingdom	31
world health	31
im blut	31
chronic lymphocytic	31
th percentile	31
cells ml	31
developed cmv	31
infected individuals	31
organ transplants	31
comorbidity index	31
cmv antibody	31
del injerto	31
reactive protein	31
cox proportional	31
skin infections	31
orthotopic liver	31
cytomegalovirus retinitis	31
immunosuppressive drugs	31
cd dose	31
higher cd	30
results obtained	30
atopic dermatitis	30
autoimmune cytopenias	30
study showed	30
cell number	30
also associated	30
affected patients	30
chest radiograph	30
cytogenetic risk	30
high prevalence	30
hyperparameter search	30
allograft function	30
antiviral drugs	30
based regimens	30
developing countries	30
die inzidenz	30
specific ctls	30
significant association	30
multifocal leukoencephalopathy	30
first years	30
immunocompromised host	30
opportunistic infection	30
wide range	30
les patients	30
corticosteroid therapy	30
transmission via	30
respiratory illness	30
one study	30
primary refractory	30
oral ganciclovir	30
empiric therapy	30
last decade	30
overall incidence	30
treatment strategies	30
randomized study	30
better outcome	30
platelet counts	30
clinical signs	30
tomato leaf	30
kg body	30
alternative donors	30
primary disease	30
sanger sequencing	30
single centre	30
immune complexes	30
infection occurs	30
end point	30
die sich	30
clinical significance	30
influenza viruses	30
complete donor	30
cell clones	30
en receptores	29
aspergillus species	29
un trasplante	29
immune deficiencies	29
specific anti	29
paediatric patients	29
living donor	29
signaling pathway	29
eingesetzt werden	29
il rg	29
cmv status	29
blood group	29
cellular rejection	29
total dose	29
predictive performance	29
kidney transplants	29
renal insufficiency	29
significant proportion	29
negative patients	29
remission status	29
specific primers	29
ebmt registry	29
significant correlation	29
previously shown	29
centre experience	29
der erreger	29
total cd	29
plasma samples	29
young adults	29
poor graft	29
vivo expansion	29
plasma cell	29
lymphocytic leukemia	29
low igg	29
myeloablative allogeneic	29
transplantation using	29
das virus	29
igg antibodies	29
haemophilus influenzae	29
post allo	29
aspergillus spp	29
competing risk	29
treated group	29
conventional chemotherapy	29
seasonal influenza	29
fever virus	29
poor mobilizers	29
antibody production	29
health status	29
renal allografts	29
letermovir prophylaxis	29
days vs	29
observational study	29
increased susceptibility	29
developed agvhd	29
rapid diagnosis	29
left ventricular	29
cells mcl	29
clinical phenotype	29
direct contact	29
patients will	29
donor specific	29
infused cd	29
steroid treatment	29
without cmv	29
also significantly	29
inflammatory disease	29
fl udarabine	29
measles virus	29
clinical disease	29
national institutes	29
group patients	29
three pts	28
received dli	28
th day	28
retrospectively evaluated	28
negative impact	28
gvl effect	28
absolute neutrophil	28
cell sources	28
adhesion molecules	28
cd lymphocyte	28
bei hiv	28
two pts	28
missense mutation	28
related infections	28
healthy volunteers	28
memory cells	28
lower risk	28
bacterial pathogens	28
recipient pairs	28
der erkrankung	28
associated mortality	28
transplant procedure	28
remained stable	28
antibiotic prophylaxis	28
without significant	28
stage renal	28
linked immunosorbent	28
respiratory secretions	28
pulmonary function	28
adverse event	28
killer cells	28
autosomal dominant	28
sct patients	28
wird die	28
cell grafts	28
iron overload	28
liegt bei	28
mainly due	28
study aimed	28
autologous peripheral	28
ischemia reperfusion	28
aldrich syndrome	28
intestinal gvhd	28
aml mds	28
pcr testing	28
pneumocystis pneumonia	28
eligible patients	28
del trasplante	28
infektion mit	28
whereas patients	28
sequence embedding	28
immune receptor	28
parenteral nutrition	28
dose tbi	28
cd depletion	28
universal prophylaxis	28
received peripheral	28
en estos	28
high rates	28
granulocyte colony	28
mixed lymphocyte	28
cmv serostatus	28
identify patients	28
age group	28
causative agent	28
study demonstrates	28
closely related	28
chronic infection	28
retrospective cohort	28
transplant characteristics	28
weeks post	28
respiratory symptoms	28
also showed	28
kg iv	28
poorly understood	28
chronic lung	28
study shows	28
der wahl	28
lymphoid organs	28
wound healing	28
pediatric hsct	28
health organization	28
viral hemorrhagic	28
conditioning therapy	28
release syndrome	28
cardiovascular disease	27
transplant complications	27
die behandlung	27
versushost disease	27
chronic inflammatory	27
cell dysfunction	27
antifungal agents	27
cell mediated	27
disease recurrence	27
rheumatoid arthritis	27
patients suffered	27
high morbidity	27
inflammatory cytokine	27
cell expansion	27
medical university	27
marrow biopsy	27
durch eine	27
disease activity	27
activated cd	27
beam group	27
organ recipients	27
dc leu	27
bloodstream infection	27
drug resistance	27
therapeutic strategies	27
twelve patients	27
related disease	27
listeria monocytogenes	27
culture supernatants	27
im gegensatz	27
genomic dna	27
treatment modality	27
lung tissue	27
auftreten von	27
sct group	27
sequence analysis	27
cr rate	27
es besteht	27
mobilized peripheral	27
relatively high	27
previously published	27
diagnose die	27
infection rate	27
reactivation occurred	27
consecutive adult	27
respiratory infection	27
interferon gamma	27
immunsupprimierten patienten	27
gene transfer	27
hemorrhagic fevers	27
mismatched donor	27
complement activation	27
potential risk	27
time quantitative	27
median overall	27
body fluids	27
may reduce	27
based gvhd	27
relative risk	27
mismatched related	27
cells transplantation	27
clinically relevant	27
donor lymphocytes	27
chronic phase	27
reverse transcriptase	27
days later	27
host immune	27
therapy may	27
die infektion	27
fed infants	27
clinical use	27
allograft dysfunction	27
sich die	27
und oder	27
proinflammatory cytokines	27
tumor cell	27
antigen processing	27
serious complication	27
hsv infection	27
submission id	27
regression models	27
der infektion	27
cell compartment	27
early detection	27
male female	26
interim analysis	26
pacientes trasplantados	26
better outcomes	26
acquired respiratory	26
transplantation patients	26
clinical picture	26
cellular immunity	26
cmv seronegative	26
prophylactic antibiotics	26
ii trial	26
within weeks	26
severe complication	26
western blotting	26
den ersten	26
chemotherapy followed	26
patient experienced	26
assessed using	26
donor transplant	26
cgd patients	26
pulmonary oedema	26
hsct using	26
jirovecii pneumonia	26
disease severity	26
los receptores	26
liver enzymes	26
regimen consisting	26
chemotherapy alone	26
inflammatory syndrome	26
patient groups	26
je nach	26
control study	26
haematopoietic cell	26
post sct	26
quality control	26
retrospective chart	26
early mortality	26
cells within	26
therapeutic approach	26
tmp smx	26
statistical difference	26
group vs	26
remains unknown	26
lymphocytic choriomeningitis	26
antibody levels	26
mice showed	26
post asct	26
evaluable patients	26
auf den	26
life threatening	26
multivariate analyses	26
children undergoing	26
negative bacilli	26
costimulation blockade	26
steroid therapy	26
cell collection	26
published data	26
van het	26
das risiko	26
interstitial pneumonitis	26
update rule	26
infektion ist	26
stage iii	26
multivariable analysis	26
ards patients	26
blood culture	26
type diabetes	26
pediatric transplant	26
transcription factors	26
old man	26
likely due	26
cytokine levels	26
hematopoetic stem	26
human immunodefi	26
blood stream	26
cellular therapy	26
deceased donor	26
exact test	26
blood transplant	26
may increase	26
years overall	26
infections caused	26
kg per	26
neural networks	26
pacientes con	26
recipients receiving	26
extremely low	26
cd mab	26
may present	26
attributable mortality	26
islet allograft	26
sich eine	25
interstitial nephritis	25
antigen detection	25
central role	25
cardiac allografts	25
sich um	25
cd ratio	25
month post	25
undergoing allo	25
measured using	25
short term	25
der gruppe	25
gold standard	25
vitro studies	25
prolonged neutropenia	25
cause significant	25
donor transplants	25
viral rna	25
foxp expression	25
therapeutic potential	25
serum ferritin	25
ebv dna	25
clinical immunology	25
cell subset	25
graft vs	25
working group	25
im kindesalter	25
therapeutic options	25
beneficial effect	25
patients develop	25
autologous hct	25
mice treated	25
tract disease	25
term graft	25
vor der	25
heavily pretreated	25
hla mismatch	25
liver biopsy	25
following transplant	25
immunosorbent assay	25
calculated using	25
cytometric analysis	25
definitive diagnosis	25
lamina propria	25
relapsed disease	25
severe neutropenia	25
promising results	25
occurred within	25
cmv igg	25
second hsct	25
function tests	25
endemic areas	25
bkv infection	25
die meisten	25
allograft vasculopathy	25
data regarding	25
hla matching	25
scoring system	25
fieber und	25
donor cd	25
recent data	25
viral dna	25
renal biopsy	25
absolute number	25
pleural effusions	25
membrane potential	25
longer duration	25
sle patients	25
inborn errors	25
like illness	25
nachgewiesen werden	25
patients developing	25
kidney injury	25
cells express	25
small bowel	25
early relapse	25
following hematopoietic	25
may develop	25
inclusion bodies	25
via breastfeeding	25
except one	25
der akuten	25
donor group	25
patients responded	25
lymphocyte proliferation	25
kinase inhibitors	25
cells stimulated	25
confocal microscopy	25
mit den	25
sequencing revealed	25
intravenous immune	25
allogenic hematopoietic	24
threatening complication	24
randomized clinical	24
mycobacterial infection	24
increasingly used	24
switched memory	24
average time	24
herpes viruses	24
increased morbidity	24
validation set	24
viral culture	24
primary outcome	24
per week	24
retrospective review	24
baseline characteristics	24
also occur	24
dose therapy	24
normal levels	24
hbv infection	24
plasma membrane	24
deep learning	24
cd high	24
patients years	24
mhc i	24
specific igg	24
humoral immune	24
disease due	24
possible role	24
novel agents	24
standard conditioning	24
diagnose einer	24
risk disease	24
organ damage	24
vaccinia virus	24
highest risk	24
including patients	24
three different	24
los casos	24
relapse free	24
hsct performed	24
recurrent sinopulmonary	24
bronquiolitis obliterante	24
acute leukaemia	24
based sequence	24
recipient mice	24
human leukocyte	24
highly effective	24
eine infektion	24
macrophage activation	24
respiratory disease	24
durch das	24
immunodeficiency disease	24
grades ii	24
lower gi	24
fusion protein	24
showed significant	24
compared using	24
hla typing	24
hla antibodies	24
antimicrobial prophylaxis	24
rabbit atg	24
elevated serum	24
tbi gy	24
allogeneic transplants	24
diagnostic tests	24
higher number	24
first report	24
unmanipulated haploidentical	24
chronic kidney	24
sot recipients	24
nhl patients	24
group received	24
cells compared	24
commercially available	24
study suggests	24
three years	24
odds ratio	24
one week	24
kann die	24
des erregers	24
virus pneumonia	24
high resolution	24
year follow	24
chronic diarrhea	24
cells obtained	24
dose melphalan	24
antigen specific	24
early phase	24
findet sich	23
nonmyeloablative conditioning	23
nipah virus	23
jiroveci pneumonia	23
significantly less	23
die eine	23
also known	23
secondary aml	23
competing risks	23
auch eine	23
bis zum	23
complete resolution	23
depleted grafts	23
linked cgd	23
innerhalb von	23
liver graft	23
practice guidelines	23
infectious pulmonary	23
molecular remission	23
creatinine levels	23
influenza vaccination	23
infected mice	23
transplant patient	23
patients sida	23
ciency virus	23
haploidentical family	23
year relapse	23
pediatric population	23
type mice	23
case presentation	23
organ disease	23
collected data	23
every months	23
es zur	23
infections due	23
induced apoptosis	23
neutralizing antibodies	23
cd monoclonal	23
parainfluenza viruses	23
significantly elevated	23
blood cd	23
severe agvhd	23
cancer center	23
increased frequency	23
cell immune	23
hdt asct	23
heterozygous mutation	23
mesenchymal stromal	23
positive selection	23
previously healthy	23
significantly correlated	23
advanced age	23
early onset	23
jc virus	23
retrospectively analysed	23
systemic treatment	23
healthy subjects	23
con el	23
risk groups	23
icu patients	23
persistent fever	23
cytokine secretion	23
developed gvhd	23
insbesondere bei	23
mortality among	23
der immunsuppression	23
immunosuppression consisted	23
cell infiltrates	23
myeloid malignancies	23
cell product	23
liver toxicity	23
secondary endpoints	23
day mortality	23
healthy control	23
failure due	23
autoimmune hemolytic	23
hematological diseases	23
least days	23
gastrointestinal disease	23
lt recipients	23
autoimmune disorders	23
international society	23
mean number	23
endothelial cell	23
standard deviation	23
biopsy specimens	23
low doses	23
may require	23
adenovirus pneumonia	23
single institution	23
good partial	23
frequently used	23
protective immunity	23
central memory	23
rabbit anti	23
antibody therapy	23
less severe	23
induction treatment	23
cytomegalovirus pneumonia	23
infection following	23
tubular necrosis	23
engraftment failure	23
phase trial	23
pet ct	23
total rna	23
first dose	23
cd memory	23
csf group	23
may affect	23
investigated whether	23
post hct	23
higher nrm	23
interstitial fibrosis	23
critical care	23
effector functions	23
posttransplant cyclophosphamide	23
greatest risk	23
indirect effects	23
better understanding	23
times daily	23
invasive candidiasis	22
transplantation unit	22
von patienten	22
cmv antibodies	22
healthy donor	22
im liquor	22
mortality due	22
spectra optia	22
und andere	22
atypical pneumonia	22
burkholderia cepacia	22
lentiviral vector	22
immunocompromised children	22
protein levels	22
elevated levels	22
therapeutic strategy	22
hematopoietic progenitor	22
analysis demonstrated	22
infections among	22
second patient	22
molecular biology	22
multiple instance	22
mucous membranes	22
patient underwent	22
single agent	22
reconstitution inflammatory	22
inflammatory responses	22
interstitial lung	22
often used	22
first step	22
usually occurs	22
also performed	22
known motif	22
adult lung	22
negative selection	22
receptor sequences	22
treatment lines	22
organ involvement	22
viral genome	22
th cytokines	22
resistance mutations	22
controlled study	22
identical donor	22
severe cap	22
draining lymph	22
one pt	22
identical siblings	22
years ago	22
hematological recovery	22
unknown origin	22
myeloablative regimen	22
within normal	22
el riesgo	22
delayed graft	22
acute hepatitis	22
choriomeningitis virus	22
human peripheral	22
igm antibodies	22
clinical impact	22
blood transfusion	22
following lung	22
encouraging results	22
time course	22
higher expression	22
new onset	22
south america	22
cause severe	22
common complication	22
simulated immunosequencing	22
myocardial infarction	22
without gvhd	22
absolute numbers	22
posttransplant period	22
depleted haploidentical	22
culture system	22
whole cohort	22
better survival	22
mosaic virus	22
refractory patients	22
rejection rate	22
hsct setting	22
cell doses	22
reduced toxicity	22
major complication	22
dose cyclophosphamide	22
immune function	22
donor transplantation	22
acute kidney	22
pcp prophylaxis	22
months following	22
important risk	22
ct scans	22
related deaths	22
pediatric intensive	22
haemorrhagic cystitis	22
immune repertoires	22
mrd group	22
relatively low	22
pulmonary infiltrates	22
hepatic veno	22
tubular epithelial	22
maintenance immunosuppression	22
seropositive recipients	22
patients whose	22
lung infections	22
received rituximab	22
neben der	22
gy tbi	22
marrow suppression	22
magnetic resonance	22
well described	22
instance learning	22
clinical utility	22
treatment group	22
solid tumor	22
tissue culture	21
lower levels	21
late onset	21
blood grafts	21
mass spectrometry	21
first weeks	21
knockout mice	21
infection among	21
early childhood	21
dass die	21
conditioned patients	21
kombination mit	21
mean follow	21
donor selection	21
longer time	21
opportunistic pathogens	21
im vordergrund	21
helper cells	21
higher dose	21
se han	21
years later	21
promoter activity	21
arterial hypertension	21
der schwangerschaft	21
refractory gvhd	21
low level	21
der klinischen	21
thymic epithelial	21
ulcerative colitis	21
inhibitory effect	21
groups according	21
disease course	21
agvhd patients	21
less common	21
resistant organisms	21
performed according	21
prognostic impact	21
different types	21
specific treatment	21
low rate	21
tlr ligands	21
gastrointestinal symptoms	21
nucleic acids	21
patients submitted	21
allowed us	21
underwent haplo	21
study comparing	21
da die	21
disease associated	21
werden durch	21
clinical study	21
disseminated infection	21
received either	21
den nachweis	21
cell aplasia	21
cell transplantations	21
advisory committee	21
average age	21
auf das	21
hies patients	21
patients remain	21
also analyzed	21
sich bei	21
usually associated	21
retrospective studies	21
hla match	21
received one	21
load monitoring	21
disease burden	21
treatment strategy	21
der therapie	21
negative control	21
oral mucositis	21
cryptococcus neoformans	21
intracellular cytokine	21
kir dl	21
und das	21
early death	21
children younger	21
immune receptors	21
responding patients	21
animal model	21
die mit	21
ccr expression	21
avium complex	21
future studies	21
learning methods	21
hla mismatched	21
dose reduction	21
antibody deficiencies	21
cell graft	21
frequent complication	21
infection rates	21
patients presenting	21
greater risk	21
light chain	21
new therapeutic	21
malignant cells	21
data support	21
frequent cause	21
hematologic diseases	21
human coronavirus	21
positive mothers	21
gvhd patients	21
received bone	21
limited number	21
variable regions	21
transplantation background	21
im vergleich	21
four weeks	21
fatal cases	21
des menschen	21
days prior	21
die cmv	21
epithelial cell	21
cell sorting	21
blood transfusions	21
suppressive function	21
mhc ii	21
human disease	21
better understand	21
log rank	21
diseases society	21
data collection	21
hepatocellular carcinoma	21
novel therapeutic	21
diseases working	21
giant cell	21
cd selected	21
positive correlation	21
abstract withdrawn	21
vzv infection	21
hematopoietic recovery	21
acute cellular	21
year pfs	21
grayscale value	21
igg antibody	20
adenovirus disease	20
resonance imaging	20
lassa fever	20
stranded dna	20
skin biopsies	20
im serum	20
matched donors	20
heart disease	20
implanted motif	20
nd cr	20
marrow derived	20
developed countries	20
congenital infection	20
pp antigenemia	20
nosocomial infections	20
cd selection	20
ii study	20
uncertain significance	20
leukocyte antigen	20
cell growth	20
lavage fluid	20
functional assays	20
therapie bei	20
transplantation cyclophosphamide	20
ist es	20
fluorescence intensity	20
viral reactivations	20
cik cell	20
den letzten	20
lymphocyte subset	20
ataxia telangiectasia	20
cells derived	20
disease prophylaxis	20
ms ms	20
cell maturation	20
donor kidney	20
cns involvement	20
freshly isolated	20
several weeks	20
without agvhd	20
thiotepa mg	20
clinimacs prodigy	20
antibodies may	20
kidney tx	20
alpha beta	20
hbv reactivation	20
independent predictors	20
frequently associated	20
survival compared	20
early stages	20
lung transplants	20
showed normal	20
pts underwent	20
sowie eine	20
bacterial suprainfection	20
also evaluated	20
gene mutations	20
fourteen patients	20
homozygous mutation	20
allo hsct	20
whole group	20
das auftreten	20
analysis using	20
foxp cells	20
heart rate	20
secondary malignancies	20
also cause	20
infants born	20
major risk	20
randomized trials	20
gvhd incidence	20
related toxicities	20
cy group	20
sowie der	20
currently used	20
waiting time	20
positive class	20
host response	20
haploidentical sct	20
less commonly	20
remains controversial	20
severe graft	20
pediatric hematology	20
der lunge	20
recombinant human	20
sixteen patients	20
active infection	20
based therapy	20
exclusion criteria	20
kaposi sarcoma	20
determined using	20
also used	20
mk cells	20
complex karyotype	20
blood count	20
bei einem	20
also received	20
absolute counts	20
disseminated intravascular	20
therapeutic intervention	20
nicht mehr	20
intravenous ribavirin	20
kann bei	20
cells play	20
guidelines recommend	20
increased levels	20
high grade	20
months respectively	20
times per	20
using standard	20
years os	20
allogenic hsct	20
und auch	20
may include	20
derived dendritic	20
gi gvhd	20
studies show	20
wie bei	20
matched family	20
expression level	20
das klinische	20
primary end	20
acute myelogenous	20
human parvovirus	20
coat protein	20
einer akuten	20
donor hsct	20
preemptive treatment	20
rna viruses	20
genetic diagnosis	20
mechanisms underlying	20
patients given	20
unknown significance	20
higher rates	20
acute tubular	20
two cohorts	20
trial comparing	20
cytokine profile	20
burden test	20
mutant mice	20
febrile illness	20
table shows	20
patients reported	20
fungal pathogens	20
room temperature	20
viral disease	20
handelt es	20
die erkrankung	20
allograft nephropathy	20
lung allograft	20
receptor excision	20
antibody mediated	20
may influence	20
confi rmed	20
reference range	20
iii iv	20
met een	20
infected livers	20
prospective trials	20
investigate whether	20
prevent gvhd	20
relapse progression	20
viral hepatitis	20
severe complications	20
clinical benefit	20
infektionen bei	20
neonatal intensive	20
still remains	20
previously demonstrated	20
among children	20
secondary malignancy	19
nod mice	19
klinische bild	19
using cd	19