trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram frequency
stem cell transplantation1018
in patients with977
as well as721
hematopoietic stem cell645
the presence of528
conflict of interest514
of patients with493
disclosure of conflict479
of conflict of479
of the patients455
cd t cells454
the use of429
a total of346
the expression of323
the development of321
the role of319
in order to318
is associated with312
the most common306
there was no305
of this study301
in this study297
with a median294
the incidence of290
the aim of286
for patients with284
the time of276
nothing to declare275
study was to271
cd and cd270
the number of268
allogeneic hematopoietic stem266
the treatment of262
at the time261
is a rare239
a median of236
one of the236
the diagnosis of230
to evaluate the223
according to the222
in children with218
this study was217
was observed in216
was associated with216
years of age214
aim of this214
due to the209
the risk of204
associated with a202
the majority of202
allogeneic stem cell200
to determine the199
median age of192
patients who received187
the effect of187
were treated with185
stem cell transplant184
was found to183
the absence of183
a median follow180
by flow cytometry177
there were no174
the patient was173
versus host disease173
graft versus host172
found to be171
at a median171
based on the170
in the first170
the median age170
acute myeloid leukemia167
the impact of163
a patient with162
median age was161
was used to159
in all patients158
has not been157
in the presence157
there was a156
in terms of155
is the most154
in addition to152
morbidity and mortality152
cumulative incidence of151
a case of150
united states background148
in patients who148
cells in the146
a history of145
peripheral blood stem145
found to have144
of the disease144
role in the144
of these patients143
acute lymphoblastic leukemia143
cd t cell142
median time to142
the age of141
t cells and141
all patients received141
compared to the140
to assess the140
mg kg day139
autologous stem cell139
in the absence137
as compared to136
increased risk of135
the immune system133
we report a133
been shown to133
abstract case report132
patients with a132
median age at132
case report text132
be associated with131
the frequency of131
all patients were130
quality of life128
in response to128
to investigate the128
been associated with127
patients who underwent127
a variety of126
hematopoietic cell transplantation126
the median time126
in combination with125
should be considered125
the setting of124
we found that123
was diagnosed with123
in the setting123
there is no122
and in the122
the outcome of121
there is a121
are associated with121
were included in120
study is to119
the importance of119
of multiple sclerosis118
were associated with118
associated with the117
it has been117
of patients who117
age was years117
the most frequent116
t cells in116
the pathogenesis of116
was detected in115
in the literature115
is the first115
case of a115
included in the114
in pediatric patients114
for the treatment114
involved in the113
and cd t112
in the study112
was found in112
stem cell source112
pediatric patients with111
of the study111
total of patients111
in all cases111
the present study110
age of years109
a diagnosis of109
t cells were108
in the treatment107
of the immune107
the case of107
analysis of the107
an important role107
sickle cell disease107
bone marrow transplantation106
of t cells106
this is the106
has been shown105
the prevalence of104
the results of104
an increase in104
were used to104
of cd cells104
in a patient104
was treated with103
whole exome sequencing103
central nervous system102
is characterized by102
is one of102
patients treated with101
the control group101
the end of100
median time of99
was defined as99
from patients with99
expression of the99
was seen in99
risk factors for99
specific t cells98
the conditioning regimen98
acute and chronic98
mutations in the98
was performed in98
a median age98
shown to be97
patients in the97
have been reported97
of children with97
to be a97
in both groups96
median follow up96
and chronic gvhd96
we present a96
patients who had96
the level of96
of patients were95
at least one95
patients had a95
as a result94
of cd t94
was significantly higher94
in of patients94
for the first94
a role in94
has been reported93
median number of93
in of the93
year overall survival93
important role in93
at our institution93
to have a93
cohort of patients93
none of the92
risk factor for92
after allogeneic hematopoietic92
results suggest that92
this study is92
the need for92
are needed to91
we report the91
months of age90
in peripheral blood90
the efficacy of90
median of days89
the effects of89
a number of89
may be a89
in these patients88
majority of patients88
significantly higher in88
was started on88
were found to88
retrospective chart review88
were observed in87
and nk cells87
significantly associated with86
the patients with86
was to evaluate86
blood stem cells86
patients with high86
who did not85
up of months85
between january and85
at time of85
during the first85
reduced intensity conditioning85
before and after85
no significant difference84
after a median84
of t cell84
data suggest that84
all patients had84
with or without83
when compared to83
analysis was performed82
most of the82
seems to be82
we performed a82
patients who were82
gd t cells82
we show that82
the context of81
compared to those81
of the most81
part of the81
on the other81
the addition of81
at the age81
patients were treated80
and bone marrow80
the activation of80
in our center80
p disclosure of80
was no significant80
group of patients79
the course of79
well as the79
in contrast to79
high levels of79
of acute gvhd78
in multiple sclerosis78
number of cd78
with a history77
in the context77
the rate of77
between the two77
we aimed to77
patients with acute77
bone marrow failure77
the patients who77
been reported in77
the percentage of77
follow up of77
the first year77
memory b cells76
in the pathogenesis76
and overall survival76
expression of cd76
blood stem cell75
related to the75
of the cases75
was used in74
in our study74
number of patients74
was assessed by74
b cells and74
were diagnosed with74
we investigated the73
associated with increased73
a cohort of73
significant difference in73
were able to73
this is a73
the other hand72
to study the72
a year old72
were found in72
the production of72
play a role71
a result of71
of cd and71
increase in the71
the lack of71
the purpose of71
in case of71
the study was71
of b cells71
the patients were71
used as a70
patients received a70
at the end70
because of the70
be considered in70
was used for70
the united states69
was higher in69
can be used69
as part of69
was performed using69
a combination of69
can lead to69
found in the68
the bone marrow68
in the present68
neutrophil and platelet68
the management of68
matched unrelated donor68
to our knowledge68
was the most68
the combination of68
no evidence of68
t and b68
contribute to the68
the regulation of68
no difference in67
the induction of67
and treatment of67
the immune response67
cell transplantation in67
a retrospective study67
with and without67
aim of the67
median duration of67
were detected in67
all patients with66
cause of death66
report a case66
safety and efficacy66
the cumulative incidence66
used in the66
there are no66
t cell activation66
were positive for66
the onset of66
of the patient66
specific cd t65
to identify the65
we describe a65
observed in patients65
t cell receptor65
human immunodeficiency virus65
one patient with65
in one patient65
bone marrow transplant65
of our study64
due to a64
allogeneic hematopoietic cell64
no significant differences64
to be associated64
to determine whether64
severe combined immunodeficiency64
depending on the64
occurred in patients64
mutation in the64
with respect to64
in the development64
associated with an64
common variable immunodeficiency63
compared with the63
more likely to63
in vitro and63
standard of care63
we retrospectively analyzed63
for the development63
conditioning regimen was63
patients with scd63
out of patients63
is important to62
shown in table62
the first time62
did not have62
to compare the62
and platelet engraftment62
for treatment of62
regulatory t cells62
to declare background62
at years of62
herpes simplex virus62
the detection of62
polymerase chain reaction62
a median time61
to analyze the61
patients with severe61
the two groups61
t cell responses61
has been associated61
overall survival was61
was confirmed by61
is the only60
in complete remission60
the identification of60
reported in the60
prior to the60
was determined by60
in the group60
a group of60
from january to60
an increased risk60
a series of60
hematopoietic stem cells60
in situ hybridization59
the patient is59
the relationship between59
we hypothesized that59
in patients and59
observed in the59
the quality of59
s of s59
high risk of59
was performed by59
we conducted a59
suggest that the59
appears to be59
the occurrence of59
inflammatory bowel disease59
in the control58
peripheral blood mononuclear58
the possibility of58
a dose of58
after the first58
been described in58
studies are needed58
the patient had58
bone marrow biopsy58
significant differences in58
age at diagnosis58
compared to patients58
old male with58
resulted in a58
clinical and laboratory58
for all patients58
all of them57
chronic granulomatous disease57
the most important57
and the patient57
blood mononuclear cells57
was diagnosed in57
have been described57
was present in57
in this patient57
aim was to57
patients with multiple57
the ability of57
intensive care unit57
at our center57
we evaluated the56
we observed that56
may lead to56
known to be56
to describe the56
died due to56
activation of the56
have shown that56
of the virus56
in the united56
end of the56
here we report56
have not been56
dose of mg56
with a high55
acute kidney injury55
at the same55
was performed on55
we present the55
diffuse large b55
and efficacy of55
the median follow55
risk of developing55
the analysis of55
a retrospective chart55
was performed with55
purpose of this55
total body irradiation55
it is important55
it is not55
is an important55
understanding of the55
t cells from55
the proportion of54
is a common54
was referred to54
to reduce the54
is caused by54
failure to thrive54
mhc class i54
of chronic gvhd54
the first days54
of the first54
the association between54
higher in the54
of patients had54
patients were included54
t cells with54
adult patients with54
in children and54
with sickle cell54
need to be54
barr virus infection54
myeloablative conditioning regimen53
not associated with53
further studies are53
in comparison with53
in comparison to53
were used for53
not statistically significant53
umbilical cord blood53
in cases of53
of the skin53
the overall survival53
the outcomes of53
is involved in53
was used as53
compared to healthy53
play an important53
full donor chimerism53
to declare p53
differences in the52
with multiple myeloma52
may contribute to52
the differential diagnosis52
of the tumor52
of stem cells52
incidence of acute52
in association with52
we observed a52
one patient had52
the only curative52
were enrolled in52
and the other52
could not be52
the type of52
this study we52
haematopoietic stem cell52
in our cohort52
are shown in51
changes in the51
the generation of51
and management of51
the objective of51
has been described51
of all patients51
we analyzed the51
at months of51
in the last51
of bone marrow51
as gvhd prophylaxis51
the start of51
old female with51
the duration of51
little is known51
squamous cell carcinoma51
the t cell51
was no difference51
incidence of relapse51
this retrospective study51
in a single51
cd cd cd51
be used to51
is based on51
the mean age51
no statistically significant50
a decrease in50
all of the50
was significantly lower50
only one patient50
and b cells50
national institute of50
minimal residual disease50
included in this50
who presented with50
was carried out50
did not receive50
a subset of50
have been shown50
and one patient50
at a dose50
has been used50
after allogeneic stem50
in multivariate analysis49
the function of49
performed a retrospective49
patients with primary49
the first case49
be due to49
be involved in49
of them were49
of allogeneic hematopoietic49
in patients undergoing49
iv acute gvhd49
to be the49
objective of this49
the degree of49
in the patient49
patient is a49
and mortality in49
was identified in49
chronic gvhd was49
median time from49
higher incidence of49
patients diagnosed with48
the activity of48
the fact that48
of nk cells48
and patients with48
from peripheral blood48
in the patients48
member of the48
the surface of48
the mechanism of48
time to neutrophil48
is known about47
such as the47
the group of47
cd cell dose47
higher risk of47
were used as47
retrospective analysis of47
present a case47
the peripheral blood47
were significantly higher47
and safety of47
difference in the47
in the case47
the median number47
after hematopoietic stem47
did not show47
next generation sequencing47
our data suggest47
we found a47
patients are alive47
in this population47
in the majority46
review of the46
we conclude that46
a case report46
t cell proliferation46
a risk factor46
chart review of46
the amount of46
in the early46
the same time46
acute gvhd was46
were divided into46
was evaluated by46
a single center46
the severity of46
for patients who46
the progression of46
in the pediatric46
differential diagnosis of46
age at transplant46
during the study46
the study period46
and mycophenolate mofetil46
and may be46
is needed to46
showed that the46
was able to45
samples were collected45
has also been45
levels of il45
patients were transplanted45
is required for45
patients who developed45
of peripheral blood45
and young adults45
patients with aml45
and in vivo45
the cells were45
and t cell45
was achieved in45
in of cases45
report text introduction45
median age years45
age of the45
present in the45
a statistically significant45
remains to be45
half of the44
in our series44
with high risk44
of morbidity and44
and of the44
likely to be44
the levels of44
be related to44
did not differ44
of cd cd44
was to determine44
with a mean44
progression free survival44
is a major44
the ability to44
the day of44
responsible for the44
autologous hematopoietic stem44
males and females44
in our patient44
the patients had44
a significant increase44
red blood cell44
the median duration43
barr virus in43
are involved in43
the influence of43
memory t cells43
used for the43
when compared with43
were performed in43
organ transplant recipients43
out of the43
in this cohort43
with history of43
mean age of43
was consistent with43
to patients with43
of the human43
may be associated43
significantly lower in43
history of recurrent43
was admitted to43
significantly higher than43
and multiple sclerosis43
increased susceptibility to43
in relation to43
patients were in43
we did not43
or chronic gvhd43
is known to43
to determine if43
led to the42
we hypothesize that42
multiple sclerosis in42
led to a42
more than of42
the safety and42
results indicate that42
significant increase in42
described in the42
vg vd t42
one patient developed42
there have been42
and can be42
the basis of42
between the groups42
in the regulation42
be used as42
and after the42
in the second42
of patients in42
a retrospective analysis42
aim of our42
high incidence of42
have been associated42
the administration of42
was shown to42
were analyzed by42
cause of morbidity42
cell transplantation for42
in patients receiving42
patient with a42
be considered as42
is essential for42
were used in42
in t cells42
been reported to42
family history of42
acute gvhd grade42
systemic lupus erythematosus42
to understand the42
correlation between the42
the general population41
acute or chronic41
after the outbreak41
during the outbreak41
of the breast41
we sought to41
in a large41
detected in the41
in this case41
was measured by41
and b cell41
followed by a41
role of the41
these results suggest41
and cd cd41
of the liver41
have been identified41
for children with41
vitro and in41
statistically significant difference41
in the differential41
a member of41
to the development41
months after hsct41
was performed to41
one patient died41
one or more40
within the first40
correlated with the40
a prospective study40
was to investigate40
our aim was40
data indicate that40
from to years40
the evaluation of40
of a patient40
our results suggest40
a marker of40
respiratory tract infections40
the tumor cells40
of cmv reactivation40
matched sibling donor40
t cells are40
patients with relapsed40
bone marrow and40
red blood cells40
b and t40
at last follow40
acute graft versus40
our study was40
all the patients40
cd cells were40
and the median40
but not in40
major cause of40
is an effective40
enrolled in the40
infection in the40
were no significant40
findings suggest that39
of hematopoietic stem39
at high risk39
we aim to39
presence of a39
increased expression of39
treatment option for39
mg m day39
engraftment was days39
and it is39
diagnosis and treatment39
children and adolescents39
was negative for39
was to assess39
of our patients39
outcome of patients39
in our institution39
their ability to39
the cause of39
the association of39
compared to controls39
the stem cell39
patients with mm39
patient had a39
are the most39
cell source was39
well as in38
not significantly different38
development of a38
factors associated with38
were identified in38
at day and38
the incidence and38
are able to38
secondary graft failure38
neutrophil engraftment was38
associated with higher38
b cell lymphoma38
and peripheral blood38
a role for38
higher in patients38
patients with hematological38
and did not38
in the past38
and cd cells38
of stem cell38
lower respiratory tract38
a period of38
patients were diagnosed38
time of the38
presented with a38
mean age was38
of the clinical38
extensive chronic gvhd38
in t cell38
of them had38
chronic kidney disease38
one of them38
needs to be38
to characterize the38
in those with38
serum levels of38
we demonstrate that38
of the cd38
conducted a retrospective38
of which were38
delta t cells38
leading to the38
with regard to38
at the university38
were detected by38
mean age at38
school of medicine38
prophylaxis consisted of38
efficacy and safety37
proportion of patients37
were the most37
of age with37
blood samples were37
evaluation of the37
two patients with37
of pediatric patients37
prior to hsct37
of the following37
of patients and37
who received a37
of the viral37
gene expression in37
impact on the37
the last years37
children with scd37
at years was37
flow cytometry and37
fludarabine mg m37
more common in37
in some cases37
disease status at37
in pts with37
with an increased37
in b cells37
with hematological malignancies37
some of the37
medical records of37
carcinoma of the37
low levels of37
time of diagnosis37
in the two37
on the basis37
is to evaluate37
to that of37
we were able37
to improve the37
higher levels of37
the central nervous37
in the diagnosis37
t cell development37
the study of37
of b cell37
with multiple sclerosis37
data were collected37
were obtained from37
caused by a36
cytotoxic t cells36
is not well36
combined immune deficiency36
the probability of36
from healthy donors36
cell proliferation and36
hla class i36
among patients with36
in univariate analysis36
to play a36
institutes of health36
and the presence36
of acute and36
data on the36
on the surface36
was performed and36
transplant related mortality36
the etiology of36
barr virus and36
for the diagnosis36
main cause of36
patients suffering from36
in which the36
to define the36
national institutes of36
or absence of36
the efficacy and36
by western blot36
all patients who36
of the two36
from diagnosis to36
of mg kg36
followed by autologous36
in the same36
urinary tract infection36
with the use36
were measured by36
leading cause of36
and severity of36
of the same36
os and pfs36
the formation of35
more frequent in35
results of the35
thought to be35
show that the35
more than one35
successfully treated with35
increased risk for35
renal transplant recipients35
defined as the35
to the hospital35
than in the35
class i molecules35
for gvhd prophylaxis35
in two patients35
we developed a35
for more than35
significant difference between35
we showed that35
a significantly higher35
t cells was35
to explore the35
at risk for35
the introduction of35
any of the35
safe and effective35
obtained from the35
retrospective review of35
immunoglobulin replacement therapy35
resulting in a35
in the number35
response to treatment35
proved to be35
which can be35
platelet engraftment was35
to increase the35
hsct in our35
causes of death35
it can be35
primary immune deficiency35
summarized in table35
are known to35
antigen presenting cells35
haploidentical stem cell35
in the peripheral35
risk of ms35
was not significantly35
were determined by35
the release of34
of patients was34
with bone marrow34
seen in the34
test was used34
study was conducted34
patients who did34
were isolated from34
blood and marrow34
in bone marrow34
was not statistically34
cells and the34
who underwent hsct34
t cell response34
patients with cgd34
in this setting34
samples from patients34
in out of34
for at least34
the cell surface34
car t cells34
we have previously34
with a higher34
due to its34
status of the34
an average of34
characterized by a34
matched related donor34
moderate to severe34
was complicated by34
with acute myeloid34
specific t cell34
high rate of34
the tumor was34
and has been34
was performed for34
are alive and34
were collected from34
donor lymphocyte infusion34
in group a34
the extent of34
the remaining patients34
consistent with the34
a significant reduction34
stem cell mobilization34
in the future34
up to of34
of cases of33
it is a33
he was diagnosed33
stem cells in33
of the left33
overall survival in33
a matched unrelated33
in a cohort33
the loss of33
risk of relapse33
in the lung33
melphalan mg m33
and number of33
peripheral blood in33
it is possible33
who underwent allo33
report text background33
up was months33
expression in the33
these data suggest33
response to the33
members of the33
caused by mutations33
to examine the33
studies have shown33
magnetic resonance imaging33
gvhd prophylaxis consisted33
autoimmune hemolytic anemia33
we retrospectively reviewed33
a panel of33
for these patients33
in the liver33
the main cause33
to healthy controls33
cd cells kg33
was analyzed by33
t cell lymphopenia33
that can be33
b cells in33
and response to33
in group b33
in the general33
the gastrointestinal tract33
a bone marrow33
the process of33
patients who are32
study aimed to32
majority of the32
the reaction norm32
disease free survival32
the contribution of32
b cells were32
our understanding of32
at that time32
year os was32
among the patients32
were no differences32
cd cells in32
age of patients32
nature of the32
an increase of32
from the same32
are required to32
the first months32
a critical role32
here we present32
cell transplantation is32
adverse events were32
considered as a32
option for patients32
was well tolerated32
found in patients32
the significance of32
which is a32
of patients undergoing32
acute gvhd and32
located in the32
presence or absence32
clinical features of32
severe chronic gvhd32
in the immune32
the control of32
two patients had32
the current study32
serve as a32
there is an32
similar to the32
the spectrum of32
was based on32
appear to be32
referred to our32
of the t32
conditioning regimen for32
follow up was32
patients undergoing allogeneic32
recurrent sinopulmonary infections32
of vitamin d32
an unrelated donor32
we studied the32
ranged from to32
differences between the32
and outcomes of32
at transplant was32
it should be32
with acute leukemia32
is a frequent32
the plasma membrane32
patients with chronic32
a reduction in32
solid organ transplant32
with newly diagnosed31
performed in patients31
was peripheral blood31
patients with pid31
abdominal pain and31
patients with sickle31
were classified as31
and lack of31
t cells to31
results demonstrate that31
gvhd prophylaxis was31
may be an31
at a single31
we compared the31
cd cd cells31
in immunocompromised patients31
results showed that31
in recent years31
cd cell count31
were evaluated by31
a child with31
single center experience31
significant impact on31
the most commonly31
no differences in31
with median age31
a primary immunodeficiency31
plays an important31
year old male31
by mutations in31
he was treated31
those who did31
it may be31
was positive for31
were performed using31
in our centre31
primary graft failure31
is a well31
divided into two31
iga and igm31
tumor cells were31
the potential to31
balb c mice31
were tested for31
were more likely31
on days and31
chronic graft versus31
cells of the31
is thought to31
a and b31
may not be31
prior to and31
characteristics of the31
the patient and31
interstitial lung disease31
male and female31
tumor necrosis factor31
analyses were performed31
these patients were31
activated t cells31
white blood cell31
statistical analysis was31
bone marrow in30
the rest of30
to be an30
found that the30
presence of the30
ranging from to30
with a diagnosis30
patients from the30
the diagnosis and30
characterized by the30
length of stay30
latent membrane protein30
mhc class ii30
after allogeneic hsct30
patients with low30
results show that30
we describe the30
immune response to30
present the case30
chart review was30
on day and30
course of the30
with the same30
in the right30
donor lymphocyte infusions30
was supported by30
a consequence of30
the presence or30
switched memory b30
patients with agvhd30
in more than30
is dependent on30
have been used30
high dose chemotherapy30
to better understand30
after initiation of30
the innate immune30
a trend towards30
b and nk30
the most frequently30
the site of30
seen in patients30
we have identified30
was evaluated in30
peripheral blood of30
after days of30
all patients engrafted30
were compared to30
sensitivity and specificity30
after stem cell30
a crucial role30
over the last30
the patients was30
of allergy and30
patients who have30
patients undergoing hsct30
the result of30
lead to a30
we examined the30
regulation of the30
who underwent allogeneic30
absolute neutrophil count30
clinical trial registry30
the correlation between30
cell lines and30
were reported in30
of viral infections30
we report our30
lead to the29
with the development29
to confirm the29
faculty of medicine29
function of the29
in the blood29
incidence of grade29
prior to transplant29
derived from the29
of the present29
the distribution of29
a retrospective review29
for min at29
could be a29
is a primary29
with primary immunodeficiency29
viral infections and29
and nk cell29
of primary immunodeficiency29
was a significant29
associated with high29
overall survival of29
can be a29
patient was diagnosed29
acute chest syndrome29
sinusoidal obstruction syndrome29
of the literature29
were transplanted in29
detected in patients29
in our experience29
the patients received29
at increased risk29
the dose of29
she was diagnosed29
to the best29
retrospective study of29
in both cases29
effect on the29
seem to be29
significant differences between29
induction of the29
is a very29
matched unrelated donors29
the cases of29
was to analyze29
and infectious diseases29
and had a29
was significantly associated29
patients with non29
no history of29
in adult patients29
at risk of29
we have shown29
was significant for29
in this group29
a review of29
and duration of29
may have a29
in patients treated29
regimen consisted of29
cells can be29
of breast cancer29
the first month29
difference between the29
first year of29
overall response rate29
respiratory syncytial virus29
at diagnosis was29
of death in29
in this retrospective29
patients did not29
the cd cd29
the patients in29
prior to transplantation29
results in a29
the clinical and29
demonstrated that the29
the results were28
were analyzed using28
large b cell28
on day was28
and disease free28
were significantly lower28
we suggest that28
risk of multiple28
study was performed28
data show that28
in the bone28
study of the28
were not significantly28
the response to28
a major cause28
conflicts of interest28
may result in28
risk factors and28
conditioning regimens were28
to our hospital28
days after the28
the increase in28
by means of28
a high risk28
patient was started28
in recipients of28
continued to have28
activity of the28
its role in28
depends on the28
cord blood transplantation28
chronic gvhd and28
the diagnosis was28
was obtained from28
and healthy controls28
could be used28
on day of28
of these two28
igg mg dl28
head and neck28
of cmv infection28
according to our28
nk cells were28
as a marker28
is mediated by28
than that of28
implicated in the28
colony stimulating factor28
are summarized in28
were in complete28
the study group28
and months after28
cytotoxic t lymphocytes28
considered to be28
patients were followed28
been implicated in28
as shown in28
total number of28
that may be28
vd t cells28
and t cells28
addition to the28
has to be28
high level of28
mesenchymal stem cells28
or in combination28
was reported in28
days after hsct28
a mutation in27
we assessed the27
also known as27
infections in the27
for the presence27
complete resolution of27
a significant difference27
pediatric oncology patients27
high risk patients27
in line with27
higher than the27
similar to that27
the goal of27
and in patients27
which may be27
was detected by27
in transplant recipients27
in a dose27
do not have27
relapsed or refractory27
cytokine release syndrome27
group compared to27
reported to be27
be used in27
was not associated27
she was started27
was notable for27
t cells by27
the patient with27
approved by the27
and for the27
the initiation of27
in cases with27
often associated with27
between and years27
been identified in27
on day after27
in accordance with27
of overall survival27
survival in patients27
common cause of27
boys and girls27
a cause of27
cd b cells27
significant decrease in27
noted to have27
during the follow27
considered in the27
in the post27
were negative for27
the patient underwent27
likely to have27
primary immunodeficiency diseases27
were compared with27
developed acute gvhd27
pediatric hematology oncology27
the median of27
biopsy of the27
it is also27
the utility of27
as a consequence27
use of a27
may play a27
patients compared to27
report the case27
of ebv in27
the application of27
and treated with27
of grade ii27
for the patients27
statistically significant differences27
for high risk27
of unknown significance27
has been demonstrated27
he was found27
had at least27
is a potentially27
describe a case27
an autosomal recessive27
in patients without27
the entire cohort27
of uncertain significance27
did not reach27
from unrelated donors27
with high dose26
occurred in the26
overall survival and26
one patient was26
to detect the26
and quality of26
were significantly increased26
cells infected with26
between patients with26
which has been26
after months of26
of these cells26
a key role26
of the total26
this case highlights26
be able to26
in the other26
used in patients26
is a significant26
may be used26
patients were enrolled26
based on these26
features of the26
the risk for26
in the course26
that of the26
that have been26
the development and26
were conditioned with26
disease caused by26
of treatment with26
time from diagnosis26
the pediatric population26
of the cells26
significant difference was26
we propose that26
known about the26
in the tumor26
as measured by26
production of il26
for the detection26
of death were26
this was a26
innate and adaptive26
severe aplastic anemia26
has been suggested26
d and d26
showed a significant26
biopsy was performed26
is difficult to26
patients had received26
a significant decrease26
of patients treated26
received myeloablative conditioning26
associated hemophagocytic lymphohistiocytosis26
univariate and multivariate26
as a potential26
in the non26
for multiple sclerosis26
were analyzed with26
was years old26
two cases of26
of the ebv26
identified in the26
specific cytotoxic t26
best of our26
t cell counts26
on the day26
used to compare26
in breast cancer26
and at the26
shown that the26
the best of26
reduction in the26
of this disease26
cd cd ra26
with no evidence26
our results show26
and stem cell26
of infectious complications26
of tumor cells26
conditioning regimen consisted26
small number of26
at months after26
revealed that the26
at this time26
immune system and26
of our knowledge26
or in the26
these results demonstrate26
source of stem26
protective effect of26
were present in26
different time points26
estimates of genetic26
in the management25
treated with a25
loss of function25
related mortality was25
the concentration of25
there has been25
mg kg on25
of patients are25
the university of25
virus infection in25
the establishment of25
patients with refractory25
the pi k25
to elucidate the25
the interaction of25
varicella zoster virus25
january and december25
two of the25
significantly different between25
of the il25
used to evaluate25
developed chronic gvhd25
leading to a25
only a few25
january to december25
consistent with a25
the availability of25
patient was treated25
is possible that25
of ebv infection25
well as a25
diagnosis and management25
caused by the25
patients with the25
the study is25
cells with a25
of immune dysregulation25
patient presented with25
to describe a25
investigate the role25
a higher risk25
time of transplant25
patients with no25
to of patients25
and viral infections25
the involvement of25
series of patients25
t cell depletion25
to respond to25
impact of the25
the first report25
upper respiratory tract25
heterozygous mutation in25
hepatitis b virus25
and outcome of25
patients with recurrent25
in cases and25
critical role in25
or bone marrow25
effect of the25
groups of patients25
allergy and infectious25
a reduced intensity25
referred to as25
institute of allergy25
i and ii25
no effect on25
without evidence of25
in the cd25
in most cases25
a part of25
has been observed25
patients have been25
index of suspicion25
th and th25
infected b cells25
the value of25
of consecutive patients25
to be effective25
in patients at25
different types of25
we demonstrated that25
cell activation and25
will be presented25
of graft failure25
cells in vitro25
in the thymus25
of the right24
inhibition of the24
severe acute respiratory24
incidence of chronic24
no conflict of24
the cost of24
and function of24
diseases such as24
donor t cells24
she was treated24
been shown that24
consecutive patients who24
of inkt cells24
report our experience24
of the lung24
had a significantly24
an effective treatment24
the nature of24
in exon of24
with r r24
course was complicated24
mg m on24
groups according to24
is consistent with24
the risk factors24
was noted in24
between and at24
differences were observed24
the source of24
median cd cell24
better understand the24
that it is24
recurrent infections and24
into two groups24
unrelated cord blood24
patients had an24
months after transplantation24
report of a24
cd t lymphocytes24
of the conditioning24
cells have been24
nk cells and24
cells as well24
can result in24
is safe and24
and the number24
defects in the24
is a life24
was positive in24
cells were positive24
is not a24
patients with advanced24
mg m d24
in a variety24
in solid organ24
and development of24
in the current24
with the presence24
reactive oxygen species24
mean number of24
the difference was24
the interaction between24
to be more24
three patients with24
is expressed in24
used to determine24
were seen in24
a safe and24
analysis showed that24
protein expression in24
the existence of24
the prevention of24
a range of24
is an uncommon24
the clinical course24
of the donor24
is able to24
it is unclear24
did not affect24
of these cases24
use of the24
chronic myeloid leukemia24
as early as24
of patients received24
occur in the24
genes involved in24
early diagnosis and24
in patients after24
outcomes of patients24
a matched related24
wide range of24
allogeneic bone marrow24
as a novel24
high prevalence of24
incidence of agvhd24
can be considered24
evaluate the impact24
patients affected by24
year cumulative incidence24
median time for24
signs and symptoms24
significantly increased in24
a matched sibling24
with relapsed refractory24
of the innate24
intensity conditioning regimen24
majority of cases24
the patient has24
in one case24
patients were alive24
shown in figure24
our results indicate24
significant differences were24
better understanding of24
a years old24
heterozygous mutations in24
chemotherapy followed by24
can also be24
first case of24
were stained with24
were defined as24
of pts with24
goal of this24
compared to control24
used to treat23
this work was23
event free survival23
between and were23
a lack of23
lymph node biopsy23
conditioning regimen and23
and should be23
the proliferation of23
decrease in the23
inborn errors of23
is required to23
is important for23
after weeks of23
of at least23
we report on23
supported by the23
were identified as23
and risk factors23
patients were male23
the b cell23
time of days23
were not statistically23
patients were evaluated23
mg dl and23
using flow cytometry23
b and c23
whitney u test23
abstract already published23
group and in23
less than years23
risk of gvhd23
results of this23
was found between23
all but one23
region of the23
examination of the23
a myeloablative conditioning23
significant reduction of23
was added to23
of the primary23
high rates of23
and activation of23
in the il23
cd cd t23
complete blood count23
and marrow transplantation23
cell dose was23
was to compare23
the length of23
lymph node metastasis23
admitted to the23
were diagnosed as23
may be useful23
as compared with23
in vivo and23
the appearance of23
who had a23
in the analysis23
be effective in23
it is known23
allogeneic haematopoietic stem23
median time between23
the most effective23
and he was23
t cell subsets23
two of them23
of regulatory t23
graft failure was23
identified as a23
at different time23
at diagnosis and23
from a matched23
was also found23
a mean of23
hsct in patients23
invasive fungal infection23
in these cases23
compared with those23
no differences were23
with increased risk23
most common cause23
the inhibition of23
be used for23
the characteristics of23
present study was23
be considered for23
in high risk23
first report of23
renal cell carcinoma23
are at risk23
with a significant23
mechanism of action23
cell receptor excision23
objective is to23
used to assess23
the period of23
records of patients23
cells from the23
stage renal disease23
even in the23
age at hsct23
the emergence of23
and a median23
to neutrophil engraftment23
and the development23
chronic gvhd were23
on the use23
the in vivo23
mouse model of23
positive for cd23
this may be23
t cells that23
two patients were23
all patients in23
retrospective cohort study23
and to identify23
old woman with23
patients with ms23
is a safe23
in b cell23
one patient who23
compared to non23
in both patients23
we have developed23
as the first23
there were patients23
no signs of23
the pathophysiology of23
to test the23
we are currently23
the transcription factor23
patients presented with23
he had a23
and patients were23
based on a23
of them received23
these patients had23
missense mutation in23
data from the23
alone or in23
data demonstrate that23
in cvid patients23
donor and recipient23
similar to those23
may be considered23
consecutive patients with23
positive correlation between23
should not be23
who had received23
of t and22
each of the22
essential for the22
average number of22
and negative for22
was not significant22
not been reported22
well tolerated and22
but it is22
been used for22
as an alternative22
key role in22
at the start22
the need of22
levels in the22
in multiple myeloma22
was approved by22
factors such as22
at day after22
poor graft function22
with common variable22
of herpes simplex22
median dose of22
age at the22
been previously reported22
was also observed22
did not find22
was performed at22
significant association between22
university hospital of22
in the human22
compared with control22
of follow up22
been found in22
who had undergone22
t and nk22
use of plerixafor22
dependent on the22
solid organ transplantation22
and it was22
not been previously22
the recruitment of22
are important for22
a central role22
in older patients22
time of transplantation22
and risk of22
adoptive transfer of22
of cd in22
function mutations in22
he was started22
early in life22
of relapse and22
source was peripheral22
that patients with22
kg cd cells22
related or unrelated22
in the left22
transplanted in cr22
yet to be22
is found in22
immune response in22
were retrospectively analyzed22
study suggests that22
up to years22
achieved complete remission22
one of these22
levels were significantly22
crucial role in22
b cells are22
was diagnosed as22
in the pre22
none of these22
we retrospectively evaluated22
the group with22
was started at22
did not develop22
many of the22
been used to22
patients with an22
old man with22
haploidentical hematopoietic stem22
bone marrow was22
occurred in of22
day and day22
clinical manifestations of22
three patients had22
to those of22
the multivariate analysis22
patients were divided22
and in vitro22
it was shown22
a better understanding22
months after the22
on the presence22
identification of the22
prospective studies are22
is related to22
significantly correlated with22
cells were isolated22
more than years22
performed in the22
of patients receiving22
of high risk22
were analyzed for22
should be performed22
significant reduction in22
subset of patients22
was higher than22
after completion of22
did not respond22
in the upper22
survival rate was22
the first patient22
p and p22
of immune suppression22
of the pts22
compared to a22
result in a22
of cd b22
free survival was22
for this study22
has been proposed22
high risk for22
acute respiratory syndrome22
from an hla22
is a novel22
this study aimed22
there are few22
lymphoblastoid cell lines22
have also been22
based on clinical22
referred to the22
group and the22
expression of p22
prevention and treatment22
is critical for22
had to be22
in any of22
expression of il22
innate immune system22
and flow cytometry22
percentage of patients22
were performed on22
s p ratio22
and to determine22
human monoclonal antibodies22
efficacy of the22
patients with hematologic22
percent of patients22
and of patients22
adolescents and young22
we used the22
viral load in22
most of them22
were analyzed in22
may also be22
associated hemophagocytic syndrome22
the molecular mechanisms22
is not clear22
days after transplantation22
lower in the22
complication of allogeneic21
effector t cells21
only curative treatment21
to be involved21
are consistent with21
and loss of21
in the expression21
a paucity of21
time to platelet21
from bone marrow21
large number of21
department of hematology21
to control the21
insights into the21
to estimate the21
between and in21
infection of the21
conditioning regimen in21
group a and21
with an average21
large cohort of21
analysis of patients21
she had a21
an extremely rare21
reported in patients21
in at least21
in colorectal cancer21
cmv reactivation was21
the beginning of21
defined as a21
linked to the21
risk of infection21
gvhd grade ii21
were assessed by21
lost to follow21
with acute gvhd21
low incidence of21
stem cells from21
engraftment was achieved21
but there was21
was due to21
is an autosomal21
with a low21
levels of the21
cells and a21
was similar in21
as stem cell21
and of them21
of a year21
is a severe21
and could be21
in a pediatric21
of t lymphocytes21
characteristics of patients21
the prognosis of21
surface expression of21
of cd on21
at any time21
who were diagnosed21
with the addition21
peripheral blood and21
is necessary to21
the feasibility of21
in a significant21
one hundred and21
the patient presented21
to have an21
our center between21
performed using the21
acute respiratory distress21
plasma levels of21
part of a21
of mg dl21
in spite of21
had a history21
the patient developed21
and fungal infections21
objective was to21
treatment for patients21
mantle cell lymphoma21
identification of a21
who were treated21
the frequency and21
no difference between21
in a prospective21
in the spleen21
on the cell21
memory b cell21
these findings suggest21
in mm patients21
respiratory distress syndrome21
difference was not21
in about of21
for detection of21
t cell function21
was lower in21
increased in the21
incidence of cmv21
after stimulation with21
increase the risk21
were measured in21
correlation was found21
our center from21
is likely to21
the normal range21
of the main21
in the multivariate21
the clinical presentation21
not show any21
with hematologic malignancies21
were performed with21
retrospectively analyzed the21
positive and negative21
of cd l21
we used a21
these results are21
prognostic significance of21
period of time21
especially in the21
gvhd prophylaxis in21
the need to21
body mass index21
children with cancer21
the intensity of21
were excluded from21
associated with poor21
study shows that21
in a child21
patients with suspected21
to develop a21
of the brain21
in the transplant21
of severe acute21
hepatitis c virus21
patients with mds21
compared to that21
a heterogeneous group21
porcine reproductive and20
positively correlated with20
of the infection20
at mg kg20
from day to20
were consistent with20
leads to the20
high morbidity and20
we decided to20
disorder characterized by20
in the adult20
of care for20
a mouse model20
patients with cd20
median overall survival20
acute gvhd in20
reproductive and respiratory20
nk cells in20
at the onset20
to the cell20
who received hsct20
viral infections in20
to the presence20
for the entire20
its ability to20
based conditioning regimen20
human endogenous retrovirus20
of gd t20
higher rates of20
c bl mice20
in the cytoplasm20
the first day20
found in of20
was significantly increased20
four patients with20
this patient population20
was not different20
epstein barr virus20
in most patients20
included patients with20
might be a20
high expression of20
which is the20
and specificity of20
no cases of20
in subjects with20
pfs and os20
sequencing was performed20
a mean age20
was bone marrow20
in cd t20
a high rate20
curative option for20
were higher in20
and cd cell20
here we describe20
in the serum20
vast majority of20
this type of20
age at transplantation20
after treatment with20
patients with all20
for the study20
primary immune deficiencies20
be an effective20
b cell development20
year after hsct20
had no effect20
primary and metastatic20
the infusion of20
levels were measured20
graft failure and20
patients responded to20
to identify patients20
in the era20
cells in patients20
the vast majority20
were more frequent20
marrow biopsy was20
with cmv reactivation20
diagnosed with a20
at day was20
and western blot20
he presented with20
was extracted from20
based gvhd prophylaxis20
bone marrow aspirate20
in conjunction with20
the host immune20
of the graft20
due to an20
a retrospective cohort20
occurred at a20
mg kg d20
due to their20
was the only20
and grade iii20
and multivariate analysis20
and one with20
less than of20
observed in of20
of adult patients20
the liver and20
and is associated20
be explained by20
are characterized by20
case highlights the20
female with a20
with the exception20
of a single20
at diagnosis of20
relapse free survival20
is due to20
biological activity of20
cyclophosphamide mg kg20
for acute myeloid20
heterogeneous group of20
quality of the20
high frequency of20
the th percentile20
virus in the20
was related to20
and respiratory syndrome20
involvement of the20
year old female20
the era of20
patients transplanted from20
over the course20