This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.
trigram | frequency |
---|---|
genome sequence of | 255 |
the human genome | 175 |
as well as | 166 |
of the genome | 136 |
the number of | 135 |
one of the | 110 |
complete genome sequence | 109 |
the presence of | 96 |
sequence of the | 95 |
of the human | 94 |
the development of | 86 |
the genome of | 83 |
analysis of the | 79 |
due to the | 69 |
in addition to | 68 |
of the viral | 64 |
such as the | 60 |
it has been | 58 |
based on the | 58 |
of rna viruses | 57 |
in the genome | 56 |
a number of | 56 |
the use of | 55 |
the evolution of | 55 |
a variety of | 53 |
in the human | 52 |
of the virus | 52 |
as a result | 48 |
genome sequences of | 48 |
the genomes of | 48 |
the identification of | 48 |
be used to | 47 |
that can be | 46 |
in order to | 46 |
the viral genome | 45 |
some of the | 44 |
the genome sequence | 43 |
there is a | 43 |
sequence of a | 42 |
the case of | 42 |
the basis of | 40 |
a result of | 40 |
the ability to | 40 |
draft genome sequence | 40 |
in the case | 40 |
can be used | 39 |
human genome project | 38 |
the stability of | 38 |
well as the | 37 |
part of the | 37 |
genome of the | 36 |
the discovery of | 35 |
dependent rna polymerase | 35 |
mutations in the | 35 |
the analysis of | 35 |
a total of | 35 |
severe acute respiratory | 34 |
associated with the | 34 |
end of the | 34 |
in which the | 33 |
the origin of | 33 |
of the two | 33 |
acute respiratory syndrome | 33 |
the absence of | 33 |
of the same | 32 |
most of the | 32 |
the generation of | 32 |
each of the | 32 |
the size of | 32 |
hepatitis c virus | 32 |
of yersinia pestis | 31 |
on the other | 31 |
large number of | 31 |
the fact that | 31 |
a set of | 31 |
the frequency of | 31 |
it is possible | 31 |
the majority of | 30 |
a and b | 30 |
led to the | 30 |
members of the | 30 |
open reading frames | 30 |
in this case | 29 |
present in the | 29 |
region of the | 28 |
because of the | 28 |
the result of | 28 |
can also be | 28 |
the host genome | 28 |
the study of | 28 |
human immunodeficiency virus | 28 |
on the basis | 27 |
sequences of the | 27 |
of a single | 27 |
it is not | 27 |
insights into the | 27 |
complete genome sequences | 27 |
there is no | 27 |
the united states | 27 |
wimmer et al | 26 |
of the most | 26 |
understanding of the | 26 |
to identify the | 26 |
in the same | 26 |
the other hand | 26 |
the genome size | 26 |
related to the | 26 |
size of the | 26 |
found in the | 26 |
in terms of | 25 |
referred to as | 25 |
important role in | 25 |
of the insert | 25 |
the formation of | 25 |
the level of | 25 |
the effect of | 25 |
a large number | 25 |
responsible for the | 25 |
and evolution of | 25 |
in the absence | 25 |
wang et al | 25 |
to be a | 25 |
of the genomes | 25 |
the emergence of | 25 |
the complete genome | 24 |
mouth disease virus | 24 |
shown in figure | 24 |
and genome size | 24 |
and analysis of | 24 |
and it is | 24 |
involved in the | 24 |
regions of the | 24 |
role in the | 24 |
rna recombination in | 24 |
diversity of the | 24 |
nucleotide sequence of | 24 |
the role of | 24 |
into the host | 23 |
the ability of | 23 |
in contrast to | 23 |
the possibility of | 23 |
of the first | 23 |
of a novel | 23 |
in this study | 23 |
the process of | 23 |
the diversity of | 23 |
addition to the | 23 |
the field of | 23 |
strand rna viruses | 23 |
many of the | 22 |
with respect to | 22 |
according to the | 22 |
found to be | 22 |
an rna virus | 22 |
high mutation rates | 22 |
of the poliovirus | 22 |
there are many | 22 |
the context of | 22 |
the production of | 22 |
the availability of | 22 |
of the host | 22 |
it is also | 22 |
the need for | 22 |
the detection of | 21 |
respiratory syndrome coronavirus | 21 |
can lead to | 21 |
similar to the | 21 |
two or more | 21 |
in rna viruses | 21 |
sequence accession jx | 21 |
in the context | 21 |
number of genes | 21 |
an important role | 21 |
immunodeficiency virus type | 21 |
the whole genome | 21 |
the same time | 21 |
the expression of | 21 |
of viral genomes | 21 |
structure of the | 21 |
in the host | 21 |
at the same | 21 |
isolated from a | 21 |
of the genes | 21 |
of rna recombination | 21 |
in the presence | 20 |
of gene expression | 20 |
the function of | 20 |
has not been | 20 |
the influenza virus | 20 |
the mutation rate | 20 |
the university of | 20 |
west nile virus | 20 |
appear to be | 20 |
of a virus | 20 |
be able to | 20 |
it should be | 20 |
in a single | 20 |
appears to be | 20 |
depending on the | 20 |
sequence accession cp | 20 |
the course of | 20 |
of rna virus | 20 |
at least one | 20 |
need to be | 19 |
have been developed | 19 |
lead to the | 19 |
of a genome | 19 |
likely to be | 19 |
is possible to | 19 |
may not be | 19 |
molla et al | 19 |
the potential to | 19 |
has been shown | 19 |
evolution of the | 19 |
of the complete | 19 |
of the rna | 19 |
characterization of the | 19 |
of viral genome | 19 |
in the united | 19 |
the relationship between | 19 |
the structure of | 19 |
of viral rna | 19 |
of genetic variation | 18 |
it is a | 18 |
of the sars | 18 |
and characterization of | 18 |
the replication of | 18 |
protein coding genes | 18 |
the lack of | 18 |
encoded by the | 18 |
differences in the | 18 |
the sequence of | 18 |
genes in the | 18 |
at the time | 18 |
the genome and | 18 |
that of the | 18 |
from a single | 18 |
whole genome sequencing | 18 |
amino acid sequences | 18 |
it is the | 18 |
considered to be | 18 |
closely related to | 18 |
the application of | 18 |
comparison of the | 18 |
comparative analysis of | 18 |
the end of | 18 |
of the protein | 18 |
the scientific community | 18 |
of the hgp | 18 |
associated with a | 18 |
is based on | 17 |
organization of the | 17 |
for the first | 17 |
that have been | 17 |
quantitative trait loci | 17 |
have been used | 17 |
vesicular stomatitis virus | 17 |
is likely to | 17 |
of the genus | 17 |
the goal of | 17 |
been shown to | 17 |
it can be | 17 |
this type of | 17 |
of the entire | 17 |
the genome is | 17 |
have been identified | 17 |
function of the | 17 |
the importance of | 17 |
and in the | 17 |
a series of | 17 |
is one of | 17 |
the distribution of | 17 |
of a new | 17 |
of the polymerase | 17 |
national center for | 17 |
acute respiratory disease | 17 |
increase in the | 16 |
the extent of | 16 |
of the bacterium | 16 |
all of the | 16 |
open reading frame | 16 |
changes in the | 16 |
infectious disease research | 16 |
dna and rna | 16 |
sequence accession jq | 16 |
of these viruses | 16 |
in the viral | 16 |
in response to | 16 |
the mechanisms of | 16 |
genome size and | 16 |
rna viruses have | 16 |
the nature of | 16 |
of infectious disease | 16 |
of recombination in | 16 |
emerging infectious diseases | 16 |
the results of | 16 |
of a gene | 16 |
the existence of | 16 |
in southern china | 15 |
of infectious diseases | 15 |
seem to be | 15 |
internal ribosomal entry | 15 |
is the most | 15 |
of genetic information | 15 |
in the following | 15 |
it is likely | 15 |
use of the | 15 |
for crop improvement | 15 |
that has been | 15 |
of the four | 15 |
influenza a virus | 15 |
thought to be | 15 |
it is important | 15 |
human genome and | 15 |
may also be | 15 |
give rise to | 15 |
for the development | 15 |
mutation rate of | 15 |
of treponema pallidum | 15 |
evolution of rna | 15 |
the causative agent | 15 |
that there is | 15 |
number of probes | 15 |
identification of the | 15 |
wide range of | 15 |
phylogenetic analysis of | 15 |
of a human | 15 |
in cell culture | 15 |
high mutation rate | 15 |
to determine the | 15 |
in some cases | 15 |
structure and function | 15 |
of mutations in | 15 |
rna viruses are | 15 |
molecular basis of | 15 |
are associated with | 15 |
simple sequence repeats | 15 |
a range of | 15 |
the consensus sequence | 15 |
of a viral | 15 |
to that of | 15 |
center for biotechnology | 14 |
used in the | 14 |
it may be | 14 |
nature of the | 14 |
our understanding of | 14 |
have shown that | 14 |
in vitro and | 14 |
is important to | 14 |
expression of the | 14 |
is not a | 14 |
was used to | 14 |
to the genome | 14 |
be used for | 14 |
the most common | 14 |
and the other | 14 |
the immune response | 14 |
gromeier et al | 14 |
of influenza a | 14 |
are likely to | 14 |
causative agent of | 14 |
the occurrence of | 14 |
to be the | 14 |
genomes of the | 14 |
a role in | 14 |
is associated with | 14 |
ribosomal entry site | 14 |
found that the | 14 |
to the human | 14 |
the spectral density | 14 |
seems to be | 14 |
the proportion of | 14 |
in the field | 14 |
of the coronavirus | 14 |
of the genomic | 14 |
has been proposed | 14 |
of viral proteins | 14 |
the accumulation of | 14 |
the impact of | 14 |
in the genomes | 14 |
of coronavirus hku | 14 |
algv r x | 14 |
have also been | 14 |
a single gene | 14 |
number of genomes | 14 |
and can be | 14 |
of viral pathogens | 14 |
portion of the | 14 |
the entire genome | 14 |
of the polyprotein | 14 |
there are two | 14 |
parts of the | 14 |
the high mutation | 14 |
for infectious disease | 14 |
in the course | 14 |
the virus to | 14 |
recombination in poliovirus | 13 |
shown to be | 13 |
in the s | 13 |
the selection of | 13 |
of poliovirus rna | 13 |
resulted in the | 13 |
development of a | 13 |
based on a | 13 |
in a cell | 13 |
complete nucleotide sequence | 13 |
domingo et al | 13 |
of genes in | 13 |
presence of a | 13 |
the need to | 13 |
of the sequence | 13 |
as part of | 13 |
by the viral | 13 |
because of their | 13 |
human adenovirus type | 13 |
of the pan | 13 |
the mechanism of | 13 |
a wide range | 13 |
the synthesis of | 13 |
by a single | 13 |
the surface of | 13 |
the cost of | 13 |
on a single | 13 |
alignment of the | 13 |
we find that | 13 |
the effects of | 13 |
only a single | 13 |
for biotechnology information | 13 |
more than one | 13 |
the first time | 13 |
replication of the | 13 |
de novo assembly | 13 |
from the same | 13 |
the time of | 13 |
identified in the | 13 |
at the level | 13 |
the complexity of | 13 |
to each other | 13 |
is essential for | 13 |
suggest that the | 13 |
view of the | 13 |
genome sequences and | 13 |
the order of | 13 |
can be found | 13 |
have to be | 13 |
has also been | 13 |
features of the | 13 |
determined by the | 13 |
of the genetic | 13 |
genome size is | 13 |
result of the | 13 |
expression of a | 13 |
of an rna | 13 |
a combination of | 13 |
the sequencing of | 13 |
the national center | 13 |
the type species | 13 |
of the immune | 13 |
in the population | 13 |
of the data | 13 |
to investigate the | 12 |
some of these | 12 |
in the past | 12 |
the action of | 12 |
a wide variety | 12 |
knowledge of the | 12 |
the same genome | 12 |
the incorporation of | 12 |
that they have | 12 |
the amount of | 12 |
of the major | 12 |
genes that are | 12 |
genome analysis of | 12 |
for rna viruses | 12 |
an analysis of | 12 |
is an important | 12 |
as an example | 12 |
observed in the | 12 |
amino acid substitutions | 12 |
evolutionary history of | 12 |
defective interfering particles | 12 |
which may be | 12 |
sequences in the | 12 |
the black death | 12 |
the viral rna | 12 |
for each of | 12 |
relative to the | 12 |
the inserted sequence | 12 |
it would be | 12 |
between the two | 12 |
could not be | 12 |
only a small | 12 |
the rate of | 12 |
development of new | 12 |
of the molecular | 12 |
a viral genome | 12 |
context of the | 12 |
identification of a | 12 |
are able to | 12 |
hepatitis b virus | 12 |
the beginning of | 12 |
along with the | 12 |
sequencing of the | 12 |
to sequence the | 12 |
the spike protein | 12 |
of the gene | 12 |
of inserted sequences | 12 |
into the genome | 12 |
depends on the | 12 |
should be noted | 12 |
the viral genomes | 12 |
the mutant spectrum | 12 |
isolated from the | 12 |
of amino acid | 12 |
of genes and | 12 |
the type of | 12 |
is likely that | 12 |
the error rate | 12 |
to provide a | 12 |
of the population | 12 |
a foreign gene | 12 |
the form of | 12 |
treponema pallidum subsp | 12 |
in this chapter | 12 |
serve as a | 12 |
used as a | 12 |
of the picornavirus | 12 |
wide variety of | 12 |
are present in | 12 |
of escherichia coli | 12 |
the range of | 12 |
ends of the | 12 |
contributed to the | 12 |
of the total | 11 |
and respiratory syndrome | 11 |
formation of a | 11 |
single nucleotide polymorphisms | 11 |
that do not | 11 |
an example of | 11 |
may be a | 11 |
with the genome | 11 |
porcine reproductive and | 11 |
mechanism by which | 11 |
from the human | 11 |
in the environment | 11 |
play an important | 11 |
as in the | 11 |
of natural products | 11 |
accumulation of mutations | 11 |
what is the | 11 |
member of the | 11 |
the transmission of | 11 |
of genes that | 11 |
the structure and | 11 |
in the future | 11 |
is also a | 11 |
which can be | 11 |
is possible that | 11 |
been shown that | 11 |
of the species | 11 |
has been reported | 11 |
in the form | 11 |
high levels of | 11 |
the probability of | 11 |
of quantitative trait | 11 |
mutation rate and | 11 |
viruses and their | 11 |
the insertion of | 11 |
origin of the | 11 |
genome sequence data | 11 |
the success of | 11 |
the human microbiome | 11 |
of the disease | 11 |
the vast majority | 11 |
sequence analysis of | 11 |
number of mutations | 11 |
compared to the | 11 |
the site of | 11 |
the coding region | 11 |
contrast to the | 11 |
reproductive and respiratory | 11 |
that there are | 11 |
presence of the | 11 |
an increase in | 11 |
the length of | 11 |
nonreplicative rna recombination | 11 |
be considered as | 11 |
of genetic diversity | 11 |
of thousands of | 11 |
needs to be | 11 |
were found to | 11 |
genetic diversity of | 11 |
tend to be | 11 |
of the national | 11 |
is similar to | 11 |
hepatitis a virus | 11 |
they have been | 11 |
of a particular | 11 |
and rna viruses | 11 |
which is a | 11 |
the protein coding | 11 |
could be used | 11 |
the immune system | 11 |
play a role | 11 |
strains of the | 11 |
showed that the | 11 |
is that of | 11 |
is composed of | 11 |
of genome replication | 11 |
complexity of the | 11 |
taxonomy of viruses | 11 |
and his colleagues | 11 |
the advent of | 11 |
are known to | 11 |
length of the | 11 |
the design of | 11 |
to generate a | 11 |
the poliovirus genome | 11 |
of the manuscript | 11 |
have the same | 11 |
of all the | 11 |
has been the | 11 |
and in vivo | 11 |
proteins involved in | 11 |
yet to be | 11 |
be noted that | 11 |
of a foreign | 11 |
all of these | 11 |
in this context | 11 |
amino acid residues | 10 |
in the consensus | 10 |
properties of the | 10 |
tools such as | 10 |
herpes simplex virus | 10 |
diseases such as | 10 |
molecular epidemiology of | 10 |
respiratory syncytial virus | 10 |
is not clear | 10 |
human genome research | 10 |
to predict the | 10 |
this process is | 10 |
the nucleic acid | 10 |
on the same | 10 |
is determined by | 10 |
of the nascent | 10 |
more than a | 10 |
of human adenovirus | 10 |
ancient pathogen genomes | 10 |
of the whole | 10 |
is that the | 10 |
been used to | 10 |
the utility of | 10 |
overlapping reading frames | 10 |
viruses that are | 10 |
in the public | 10 |
genome of a | 10 |
majority of the | 10 |
to a new | 10 |
a novel coronavirus | 10 |
the history of | 10 |
genome sequencing and | 10 |
sites in the | 10 |
salmonella enterica serovar | 10 |
also known as | 10 |
there are several | 10 |
the potential of | 10 |
multiple sequence alignment | 10 |
known to be | 10 |
in the first | 10 |
c cd pr | 10 |
avian influenza virus | 10 |
drug and vaccine | 10 |
genome segment reassortment | 10 |
can only be | 10 |
the genetic information | 10 |
of the proteins | 10 |
genomes from a | 10 |
text text text | 10 |
genomes have been | 10 |
in a genome | 10 |
such as those | 10 |
be used as | 10 |
in the laboratory | 10 |
lead to a | 10 |
overview of the | 10 |
of a bacterial | 10 |
a single nucleotide | 10 |
genes in a | 10 |
has been estimated | 10 |
see for example | 10 |
molecular mechanisms of | 10 |
in the virus | 10 |
the hypothesis that | 10 |
is required for | 10 |
amino acid sequence | 10 |
with a high | 10 |
be found in | 10 |
resulted in a | 10 |
of the inserted | 10 |
basis of the | 10 |
on the surface | 10 |
proteins encoded by | 10 |
the virus and | 10 |
within the same | 10 |
this is a | 10 |
only a few | 10 |
in the dna | 10 |
vitro and in | 10 |
in a viral | 10 |
the sequences of | 10 |
over the past | 10 |
of ancient pathogen | 10 |
human immunodefi ciency | 10 |
the set of | 10 |
the near future | 10 |
andino et al | 10 |
the genes in | 10 |
are found in | 10 |
may have been | 10 |
in this way | 10 |
surrounded by an | 10 |
are responsible for | 10 |
appeared to be | 10 |
in this work | 10 |
and so on | 10 |
this can be | 10 |
in the early | 10 |
also be used | 10 |
in the development | 10 |
mueller and wimmer | 10 |
is important for | 10 |
density oligonucleotide arrays | 10 |
comparative genomics of | 10 |
a consequence of | 10 |
of at least | 10 |
is not the | 10 |
suggests that the | 10 |
added to the | 10 |
this suggests that | 10 |
viral and cellular | 10 |
has led to | 10 |
the spread of | 10 |
history of the | 10 |
note that the | 10 |
genome sequencing projects | 10 |
in the number | 10 |
has recently been | 10 |
to reduce the | 10 |
as a reference | 10 |
xiang et al | 10 |
they can be | 10 |
as shown in | 10 |
classifi cation of | 10 |
be involved in | 10 |
the department of | 10 |
the start of | 10 |
the core genome | 10 |
stability of the | 10 |
that could be | 10 |
similar to that | 10 |
the source of | 10 |
pan subsp pertenue | 10 |
that rna viruses | 10 |
of the other | 10 |
that are not | 10 |
that may be | 10 |
the genetic basis | 10 |
of an organism | 10 |
to the presence | 10 |
of the cellular | 10 |
in hong kong | 10 |
a tool for | 10 |
gene expression and | 10 |
sequence of an | 10 |
those of the | 10 |
natural products discovery | 10 |
was found to | 10 |
sequence of bacteriophage | 9 |
defined as the | 9 |
variation in the | 9 |
viruses such as | 9 |
inserted into the | 9 |
of a given | 9 |
half of the | 9 |
of viruses and | 9 |
that does not | 9 |
and expression of | 9 |
the first two | 9 |
map of the | 9 |
its ability to | 9 |
the initiation of | 9 |
completion of the | 9 |
development of the | 9 |
are similar to | 9 |
this is the | 9 |
in the poliovirus | 9 |
in these cases | 9 |
vast majority of | 9 |
different types of | 9 |
the conservation of | 9 |
the creation of | 9 |
of a species | 9 |
genetic basis of | 9 |
the sum of | 9 |
c pr and | 9 |
results of the | 9 |
closely related species | 9 |
genome to be | 9 |
genome can be | 9 |
to study the | 9 |
the efficiency of | 9 |
the human body | 9 |
coronavirus hku was | 9 |
a means to | 9 |
the viral polymerase | 9 |
in the clinic | 9 |
on the array | 9 |
and public health | 9 |
genetic variation of | 9 |
to the development | 9 |
mouse hepatitis virus | 9 |
a virus to | 9 |
serves as a | 9 |
have not been | 9 |
is a single | 9 |
the th century | 9 |
the same as | 9 |
be interesting to | 9 |
information on the | 9 |
is necessary to | 9 |
horizontal gene transfer | 9 |
respiratory syndrome virus | 9 |
account for the | 9 |
the fidelity of | 9 |
was determined in | 9 |
the host cell | 9 |
in the near | 9 |
other rna viruses | 9 |
is thought to | 9 |
of which are | 9 |
of data and | 9 |
large numbers of | 9 |
multilocus sequence typing | 9 |
in the formation | 9 |
available at https | 9 |
as a tool | 9 |
of closely related | 9 |
discussed in the | 9 |
beginning of the | 9 |
genes involved in | 9 |
gene expression in | 9 |
are difficult to | 9 |
and in vitro | 9 |
resulting in a | 9 |
a group of | 9 |
relative abundance of | 9 |
it possible to | 9 |
for the detection | 9 |
of influenza virus | 9 |
genome sequencing for | 9 |
viruses with a | 9 |
minimum hitting set | 9 |
is encoded by | 9 |
rate at which | 9 |
that some of | 9 |
this means that | 9 |
is responsible for | 9 |
is related to | 9 |
the molecular mechanisms | 9 |
the reference strain | 9 |
suggesting that the | 9 |
described in the | 9 |
is difficult to | 9 |
of the three | 9 |
been developed to | 9 |
of the influenza | 9 |
to be involved | 9 |
recombination between the | 9 |
mutation rates for | 9 |
invertebrate vectors of | 9 |
that it is | 9 |
to note that | 9 |
the task of | 9 |
be related to | 9 |
be responsible for | 9 |
the molecular basis | 9 |
the integration of | 9 |
between viruses and | 9 |
the human population | 9 |
an overview of | 9 |
the basis for | 9 |
of the mutation | 9 |
stability of inserted | 9 |
in this section | 9 |
the possibility that | 9 |
the involvement of | 9 |
to estimate the | 9 |
the introduction of | 9 |
frequency of the | 9 |
strains isolated from | 9 |
the genome sequences | 9 |
insertions and deletions | 9 |
of adenovirus type | 9 |
in rna virus | 9 |
suggested that the | 9 |
to the evolution | 9 |
of the malaria | 9 |
to meet the | 9 |
been applied to | 9 |
sequences can be | 9 |
fact that the | 9 |
of template switching | 9 |
of the mechanisms | 9 |
to understand the | 9 |
have been found | 9 |
compared with the | 9 |
in infectious disease | 9 |
local alignment search | 9 |
analyses of the | 9 |
the section on | 9 |
viruses have been | 9 |
genes related to | 9 |
of a pathogen | 9 |
sequences within the | 9 |
the accuracy of | 9 |
infectious disease informatics | 9 |
included on the | 9 |
the poliovirus polyprotein | 9 |
in recent years | 9 |
of more than | 9 |
it will be | 9 |
stranded dna viruses | 9 |
implications for the | 9 |
of the current | 9 |
a collection of | 9 |
in escherichia coli | 9 |
at the end | 9 |
the amino acid | 9 |
genes responsible for | 9 |
into a single | 9 |
there is an | 9 |
alignment search tool | 9 |
china complete genome | 9 |
the rate at | 9 |
replicate their genomes | 9 |
is the number | 9 |
genome consists of | 9 |
the sars coronavirus | 9 |
basic local alignment | 9 |
of a specific | 9 |
mutation rates of | 9 |
in genome replication | 9 |
one or more | 9 |
of genetic material | 9 |
the cellular receptor | 9 |
rna viruses is | 9 |
tool for the | 9 |
in the low | 9 |
genome tiling arrays | 9 |
has the potential | 9 |
study of the | 9 |
relationship between the | 9 |
the genetic diversity | 9 |
result in a | 9 |
a lack of | 9 |
initiation of translation | 9 |
the evolutionary history | 9 |
the regulation of | 9 |
mutational analysis of | 9 |
is able to | 9 |
murine leukemia virus | 9 |
strains in the | 9 |
out of the | 9 |
of deleterious mutations | 9 |
the diagnosis of | 9 |
as described earlier | 9 |
been identified in | 9 |
an understanding of | 9 |
nm in diameter | 9 |
in many cases | 8 |
of these genes | 8 |
a member of | 8 |
the other two | 8 |
contribute to the | 8 |
has been identified | 8 |
a prerequisite for | 8 |
for the evolution | 8 |
caused by a | 8 |
a complete genome | 8 |
recombination between rna | 8 |
the larger the | 8 |
in which they | 8 |
of its genome | 8 |
depend on the | 8 |
of oligonucleotide arrays | 8 |
a database of | 8 |
of the replication | 8 |
and does not | 8 |
used for the | 8 |
it is necessary | 8 |
and comparative genomics | 8 |
than that of | 8 |
and genotyping of | 8 |
the detection and | 8 |
from the genome | 8 |
around the world | 8 |
of the sequences | 8 |
the location of | 8 |
genome sequencing project | 8 |
of genomic data | 8 |
integration into the | 8 |
is present in | 8 |
have been published | 8 |
and pan subsp | 8 |
the capacity of | 8 |
to be highly | 8 |
the transfer of | 8 |
dynamics of the | 8 |
of these data | 8 |
of the replicative | 8 |
in a given | 8 |
type iii secretion | 8 |
friedberg et al | 8 |
the mechanism by | 8 |
the properties of | 8 |
genome research institute | 8 |
to address the | 8 |
of genomic and | 8 |
the quality of | 8 |
model of the | 8 |
the nascent strand | 8 |
in the process | 8 |
morbidity and mortality | 8 |
are the most | 8 |
substitutions in the | 8 |
of a universal | 8 |
copies of the | 8 |
pan subsp pallidum | 8 |
and amino acid | 8 |
of the original | 8 |
is involved in | 8 |
to the reference | 8 |
of poliovirus in | 8 |
there are a | 8 |
genetic variation in | 8 |
of the covid | 8 |
the addition of | 8 |
the capacity to | 8 |
of virus genomes | 8 |
rna and dna | 8 |
of severe acute | 8 |
with the size | 8 |
of the sabin | 8 |
each of these | 8 |
were used to | 8 |
in poliovirus rna | 8 |
of the rice | 8 |
national human genome | 8 |
a change in | 8 |
could lead to | 8 |
bovine viral diarrhea | 8 |
more and more | 8 |
viral diarrhea virus | 8 |
species of the | 8 |
the problem of | 8 |
case of the | 8 |
corresponding to the | 8 |
it is interesting | 8 |
version of this | 8 |
and the ability | 8 |
viral and host | 8 |
was used for | 8 |
example of a | 8 |
plays an important | 8 |
group b streptococcus | 8 |
viruses in the | 8 |
is used to | 8 |
of dna sequences | 8 |
genome sequencing of | 8 |
as described in | 8 |
hepatitis delta virus | 8 |
murine hepatitis virus | 8 |
pais of subsp | 8 |
better understanding of | 8 |
of the organism | 8 |
mechanisms by which | 8 |
more likely to | 8 |
middle east respiratory | 8 |
is also possible | 8 |
by an envelope | 8 |
and maintenance of | 8 |
the bacterium in | 8 |
a subset of | 8 |
deletion of the | 8 |
which could be | 8 |
be used in | 8 |
of the strains | 8 |
east respiratory syndrome | 8 |
mechanism of rna | 8 |
as a template | 8 |
of dna sequence | 8 |
of stem cells | 8 |
and relative density | 8 |
resulting in the | 8 |
in the cell | 8 |
the most important | 8 |
the mitochondrial genome | 8 |
relative abundance and | 8 |
analysis of viral | 8 |
functional elements in | 8 |
was the first | 8 |
high rate of | 8 |
in the analysis | 8 |
to find the | 8 |
humans and pigs | 8 |
agents of bioterrorism | 8 |
the increase of | 8 |
the dna sequence | 8 |
in spite of | 8 |
genome and the | 8 |
led to a | 8 |
and that the | 8 |
human and animal | 8 |
viruses have evolved | 8 |
analysis of a | 8 |
sequence can be | 8 |
to better understand | 8 |
level of the | 8 |
of positive selection | 8 |
most closely related | 8 |
predicted to be | 8 |
evolution of picornaviruses | 8 |
round primers lpw | 8 |
gmyl et al | 8 |
used to identify | 8 |
infectious bronchitis virus | 8 |
the dynamics of | 8 |
analysis of genetic | 8 |
the query sequence | 8 |
genomes in the | 8 |
the public domain | 8 |
of hepatitis c | 8 |
of the dna | 8 |
and hz shx | 8 |
single nucleotide polymorphism | 8 |
advantage of the | 8 |
a viral population | 8 |
the virus in | 8 |
of the viruses | 8 |
acid substitutions in | 8 |
human genome sequence | 8 |
the reconstruction of | 8 |
insertion of a | 8 |
to identify and | 8 |
a powerful tool | 8 |
terminus of the | 8 |
the cause of | 8 |
in case of | 8 |
are composed of | 8 |
course of evolution | 8 |
regions in the | 8 |
cao and wimmer | 8 |
synthesis of the | 8 |
across the genome | 8 |
to be used | 8 |
consistent with the | 8 |
little is known | 8 |
synthesis of a | 8 |
to reach the | 8 |
may lead to | 8 |
be necessary to | 8 |
sequencing the human | 8 |
belong to the | 8 |
the nucleotide sequence | 8 |
and development of | 8 |
homologous rna recombination | 8 |
and diversity of | 8 |
infl uenza virus | 8 |
of the mutant | 8 |
genome sequence and | 8 |
the rna polymerase | 8 |
were found in | 8 |
indicates that the | 8 |
of genomes of | 8 |
a measure of | 8 |
there is evidence | 8 |
and the development | 8 |
site of the | 8 |
of the large | 8 |
alv genome assembly | 8 |
of the more | 8 |
the comparison of | 8 |
a genome is | 8 |
the dpav genome | 8 |
the list of | 8 |
primers lpw lpw | 8 |
and do not | 8 |
was supported by | 8 |
deletions in the | 8 |
a model for | 8 |
the treatment of | 8 |
fas ii system | 8 |
role of the | 8 |
genomes can be | 8 |
play important roles | 8 |
over the last | 8 |
the correlation between | 8 |
have led to | 8 |
of sequence data | 8 |
genome as a | 8 |
that most of | 8 |
a web server | 8 |
not found in | 8 |
willemsen et al | 8 |
linked to the | 8 |
has been used | 8 |
of porcine deltacoronavirus | 8 |
due to their | 8 |
samples of pigs | 8 |
we will discuss | 8 |
the activity of | 8 |
the ends of | 8 |
the case for | 8 |
human genome was | 8 |
in the current | 8 |
of the global | 8 |
in clinical microbiology | 8 |
the ratio of | 8 |
and function of | 8 |
are in the | 8 |
small number of | 8 |
of this type | 8 |
were able to | 8 |
by at least | 8 |
of viruses with | 8 |
interactions between the | 7 |
as a whole | 7 |
nomoto et al | 7 |
genetic recombination of | 7 |
will lead to | 7 |
closely related viruses | 7 |
the reference genome | 7 |
the recovery of | 7 |
the primary structure | 7 |
for a given | 7 |
of an outbreak | 7 |
the choice of | 7 |
mutation rates in | 7 |
on the nature | 7 |
elements in the | 7 |
genome sequencing in | 7 |
for dna and | 7 |
the value of | 7 |
is not possible | 7 |
the correlation function | 7 |
report of the | 7 |
the key to | 7 |
of the capsid | 7 |
to play a | 7 |
a common ancestor | 7 |
of the invention | 7 |
in humans and | 7 |
have evolved to | 7 |
harber et al | 7 |
in virus genomes | 7 |
in the identification | 7 |
assigned to an | 7 |
group of viruses | 7 |
escherichia coli k | 7 |
gov dmid genomes | 7 |
incorporated into the | 7 |
a new era | 7 |
assigned to the | 7 |
leading to the | 7 |
mutation and recombination | 7 |
remains to be | 7 |
absent in the | 7 |
for gene therapy | 7 |
viruses can be | 7 |
the degree of | 7 |
of the following | 7 |
viruses of the | 7 |
genome is the | 7 |
example of this | 7 |
is capable of | 7 |
variations in the | 7 |
to an order | 7 |
the most widely | 7 |
fragment of the | 7 |
to the a | 7 |
in the replication | 7 |
another example of | 7 |
being able to | 7 |
rate of the | 7 |
can act as | 7 |
and complexity of | 7 |
holland et al | 7 |
of complete genome | 7 |
not the only | 7 |
have been a | 7 |
the emcv ires | 7 |
different levels of | 7 |
that the genome | 7 |
species in the | 7 |
is shown in | 7 |
viruses that have | 7 |
sequence of mycobacterium | 7 |
text texttext text | 7 |
to the host | 7 |
used in this | 7 |
of this review | 7 |
institutes of health | 7 |
the replacement of | 7 |
is dependent on | 7 |
limited number of | 7 |
the phylogenetic analysis | 7 |
prokaryotic and eukaryotic | 7 |
nejsum et al | 7 |
are used to | 7 |
has been suggested | 7 |
known as the | 7 |
whole genome sequences | 7 |
an outbreak of | 7 |
access to the | 7 |
national institutes of | 7 |
to provide the | 7 |
kb sliding windows | 7 |
and infectious diseases | 7 |
to assume that | 7 |
data generated by | 7 |
the nuclear genomes | 7 |
the exchange of | 7 |
internal ribosome entry | 7 |
the completion of | 7 |
are shown in | 7 |
can result in | 7 |
database at ncbi | 7 |
within a species | 7 |
frequency of recombination | 7 |
of a variety | 7 |
the most likely | 7 |
levels of the | 7 |
are designed to | 7 |
by homologous recombination | 7 |
that in the | 7 |
sequencing and analysis | 7 |
as a means | 7 |
to the other | 7 |
have been sequenced | 7 |
to obtain a | 7 |
discovery of a | 7 |
and they are | 7 |
a virus with | 7 |
li et al | 7 |
as it is | 7 |
estimated to be | 7 |
a new genome | 7 |
to be discovered | 7 |
virus genomes are | 7 |
does not require | 7 |
amino acid substitution | 7 |
the uncorrelated background | 7 |
are unlikely to | 7 |
the understanding of | 7 |
viral mutation rates | 7 |
brome mosaic virus | 7 |
can be divided | 7 |
is expected to | 7 |
dependent rna polymerases | 7 |
of the identified | 7 |
there was no | 7 |
protein coding regions | 7 |
of the family | 7 |
carried out in | 7 |
total number of | 7 |
data from the | 7 |
extent to which | 7 |
with a large | 7 |
texttext text text | 7 |
which have been | 7 |
draft genome sequences | 7 |
the physical genome | 7 |
means that the | 7 |
recombination in rna | 7 |
been developed and | 7 |
human genome is | 7 |
sequence repeats in | 7 |
an important factor | 7 |
surface of the | 7 |
not assigned to | 7 |
for the analysis | 7 |
among virus genomes | 7 |
study of ancient | 7 |
the prediction of | 7 |
data on the | 7 |
start of the | 7 |
for a single | 7 |
poliovirus rna replication | 7 |
a virus that | 7 |
some rna viruses | 7 |
at the genome | 7 |
of the form | 7 |
is required to | 7 |
rna virus genomes | 7 |
common ancestor of | 7 |
text text texttext | 7 |
the reference sequence | 7 |
the one hand | 7 |
of virus evolution | 7 |
avian infectious bronchitis | 7 |
protein coding region | 7 |
attached to the | 7 |
are encoded by | 7 |
genomes with the | 7 |
in human and | 7 |
genetic diversity within | 7 |
has been applied | 7 |
and consequences of | 7 |
the relative abundance | 7 |
diversity in the | 7 |
studies on the | 7 |
genome size of | 7 |
located in the | 7 |
fourier spectral density | 7 |
portions of the | 7 |
mutation rate is | 7 |
a matter of | 7 |
of the virion | 7 |
is considered to | 7 |
the characterization of | 7 |
that will be | 7 |
much of the | 7 |
in which a | 7 |
would like to | 7 |
was observed in | 7 |
given rise to | 7 |
fraction of the | 7 |
of the black | 7 |
the nucleocapsid is | 7 |
human genome in | 7 |
has been made | 7 |
is interesting to | 7 |
provides insights into | 7 |
to develop a | 7 |
are based on | 7 |
the genome to | 7 |
sets of genes | 7 |
a requirement for | 7 |
human parvovirus b | 7 |
genome organization of | 7 |
recognition of the | 7 |
it is now | 7 |
can be considered | 7 |
it does not | 7 |
serogroup b meningococcus | 7 |
emerging and re | 7 |
most widely used | 7 |
been estimated that | 7 |
types of data | 7 |
can be predicted | 7 |
for the production | 7 |
measure of the | 7 |
paul et al | 7 |
complete genome sequencing | 7 |
genomics and transcriptomics | 7 |
for all the | 7 |
by the number | 7 |
enterica serovar typhi | 7 |
appear to have | 7 |
been proposed that | 7 |
the acquisition of | 7 |
the rest of | 7 |
and of the | 7 |
the authors declare | 7 |
important roles in | 7 |
orders of magnitude | 7 |
genes present in | 7 |
mutation rates and | 7 |
dependent on the | 7 |
genetic analysis of | 7 |
of mycobacterium tuberculosis | 7 |
of the pathogen | 7 |
example is the | 7 |
in vivo and | 7 |
introduction of the | 7 |
to the public | 7 |
lateral gene transfer | 7 |
occurred in the | 7 |
restricted to the | 7 |
sequencing of a | 7 |
evidence for the | 7 |
a family of | 7 |
the national institutes | 7 |
for the discovery | 7 |
are discussed in | 7 |
were detected in | 7 |
used to predict | 7 |
it is still | 7 |
there is also | 7 |
in both the | 7 |
they do not | 7 |
supported by the | 7 |
the first step | 7 |
a gene that | 7 |
of the high | 7 |
in favor of | 7 |
the assembly of | 7 |
of staphylococcus aureus | 7 |
have the potential | 7 |
for infectious diseases | 7 |
derived from a | 7 |
used by the | 7 |
do not have | 7 |
agent of plague | 7 |
nucleotide sequences of | 7 |
example of the | 7 |
been found in | 7 |
immunodefi ciency virus | 7 |
genomes of human | 7 |
in genome size | 7 |
and assembly of | 7 |
a platform for | 7 |
goal of the | 7 |
at least two | 7 |
of a protein | 7 |
a list of | 7 |
there are four | 7 |
with that of | 7 |
and treatment of | 7 |
replication and pathogenesis | 7 |
genome and singletons | 7 |
of high mutation | 7 |
elements of the | 7 |
will also be | 7 |
pizza et al | 7 |
in all the | 7 |
fold increase in | 7 |
rna virus evolution | 7 |
in other words | 7 |
at the protein | 7 |
this is true | 7 |
sites of the | 7 |
gene in the | 7 |
model for the | 7 |
the enveloping curve | 7 |
of rna synthesis | 7 |
in the reference | 7 |
some of them | 7 |
in an rna | 7 |
on the one | 7 |
as a single | 7 |
of the individual | 7 |
be carried out | 7 |
these viruses have | 7 |
of dna and | 7 |
sequence of porcine | 7 |
in the study | 7 |
two of the | 7 |
been associated with | 7 |
part of a | 7 |
abundance and relative | 7 |
a region of | 7 |
to be sequenced | 7 |
coronavirus hku in | 7 |
can be easily | 7 |
but also for | 7 |
together with the | 7 |
and the number | 7 |
mapping of the | 7 |
the national human | 7 |
focused on the | 7 |
and the genome | 7 |
a long time | 7 |
can be achieved | 7 |
their ability to | 7 |
eradication of poliovirus | 7 |
rna polymerase ii | 7 |
are capable of | 7 |
a bacterial genome | 7 |
the significance of | 7 |
large dna viruses | 7 |
analysis of dna | 6 |
characterization of a | 6 |
of the experiment | 6 |
of the proviral | 6 |
and references therein | 6 |
are the result | 6 |
of the physical | 6 |
be due to | 6 |
maintenance of the | 6 |
genomes and the | 6 |
any of the | 6 |
and approved the | 6 |
rna viruses and | 6 |
the age of | 6 |
only one of | 6 |
were subjected to | 6 |
of the project | 6 |
exon mutator phenotype | 6 |
polymerase chain reaction | 6 |
recombination in the | 6 |
spectral density of | 6 |
the viability of | 6 |
bovine respiratory disease | 6 |
omics alv genome | 6 |
the genome at | 6 |
of the information | 6 |
lu et al | 6 |
in the regulation | 6 |
of infl uenza | 6 |
the extent to | 6 |
genome size in | 6 |
within the genome | 6 |
increase or decrease | 6 |
of the evolution | 6 |
be restricted to | 6 |
is not required | 6 |
to infer the | 6 |
its genome size | 6 |
a class of | 6 |
of the main | 6 |
from patients with | 6 |
of mutation rates | 6 |
associated with human | 6 |
parasite plasmodium falciparum | 6 |
density of ssrs | 6 |
generated by the | 6 |
in the subfamily | 6 |
viruses may be | 6 |
forms of the | 6 |
subcellular localization of | 6 |
will be discussed | 6 |
and the second | 6 |
as the number | 6 |
substitutions per nucleotide | 6 |
the hgp was | 6 |
and their hosts | 6 |
of outer membrane | 6 |
the genes and | 6 |
is not assigned | 6 |
are part of | 6 |
genome assembly al | 6 |
contributing to the | 6 |
in y axis | 6 |
of point mutations | 6 |
will provide a | 6 |
for a number | 6 |
is a major | 6 |
participate in the | 6 |
in this category | 6 |
the capsid proteins | 6 |
can then be | 6 |
map of h | 6 |
as the reference | 6 |
be infected with | 6 |
traits such as | 6 |
the evolution and | 6 |
sequences that are | 6 |
can be made | 6 |
plant rna viruses | 6 |
to adapt to | 6 |
the nature and | 6 |
of viral sequences | 6 |
the ssrs relative | 6 |
functions of the | 6 |
rate of rna | 6 |
the idea of | 6 |
selection of the | 6 |
a reduction in | 6 |
been used in | 6 |
the bronze age | 6 |
coronavirus hku strains | 6 |
for prediction of | 6 |
by which the | 6 |
international committee on | 6 |
zhou et al | 6 |
genetic diversity and | 6 |
are unable to | 6 |
to form a | 6 |
infl uenza viruses | 6 |
might have been | 6 |
and their associated | 6 |
the risk of | 6 |
unable to replicate | 6 |
a comparison of | 6 |
from pigs in | 6 |
noncoding region of | 6 |
to explore the | 6 |
mapping and sequencing | 6 |
variation of the | 6 |
complete genomes of | 6 |
in light of | 6 |
in the late | 6 |
of the c | 6 |
the roslin institute | 6 |
with regard to | 6 |
novo assembly of | 6 |
of west nile | 6 |
in the next | 6 |
and vice versa | 6 |
of genomes and | 6 |
and is a | 6 |
the behavior of | 6 |
respiratory disease in | 6 |
winzeler et al | 6 |
of human dna | 6 |
consists of a | 6 |
that contribute to | 6 |
sequence accession jn | 6 |
porcine epidemic diarrhea | 6 |
to make the | 6 |
for example the | 6 |
large population sizes | 6 |
primary structure of | 6 |
it was shown | 6 |
are examples of | 6 |
it was also | 6 |
correspond to the | 6 |
capacity of the | 6 |
in less than | 6 |
response of the | 6 |
human genome the | 6 |
zwart et al | 6 |
the rice genome | 6 |
there are some | 6 |
genome of an | 6 |
the authors thank | 6 |
of the sequencing | 6 |
recombination has been | 6 |
the two strains | 6 |
in this review | 6 |
in the detection | 6 |
genetic recombination in | 6 |
to explain the | 6 |
by the orf | 6 |
malaria parasite plasmodium | 6 |
the best adapted | 6 |
to give rise | 6 |
to participate in | 6 |
the performance of | 6 |
with a single | 6 |
the alignment of | 6 |
of humans and | 6 |
small genome size | 6 |
of dna sequencing | 6 |
very similar to | 6 |
important factor in | 6 |
as compared to | 6 |
description of the | 6 |
so that the | 6 |
a human host | 6 |
the rna genome | 6 |
transcriptome map of | 6 |
in silico rea | 6 |
of rna genomes | 6 |
for which no | 6 |
genomic analysis of | 6 |
cells of the | 6 |
is believed that | 6 |
neutralization antigenic sites | 6 |
have been made | 6 |
primordial germ cells | 6 |
of molecular biology | 6 |
and on the | 6 |
the improvement of | 6 |
genomes from the | 6 |
of a recombinant | 6 |
the same cell | 6 |
been identified as | 6 |
possible to identify | 6 |
the control of | 6 |
a whole genome | 6 |
human microbiome project | 6 |
in the sequence | 6 |
type species of | 6 |
to produce the | 6 |
is known about | 6 |
is surrounded by | 6 |
to create a | 6 |
the nucleus of | 6 |
vectors of infectious | 6 |
of nucleic acid | 6 |
can be isolated | 6 |
the genome level | 6 |
the poliovirus ires | 6 |
limited by the | 6 |
other types of | 6 |
which is an | 6 |
would be interesting | 6 |
for influenza virus | 6 |
cannot be excluded | 6 |
of the cell | 6 |
a function of | 6 |
have been isolated | 6 |
whole genome amplification | 6 |
into the viral | 6 |
jex et al | 6 |
to be an | 6 |
range of genome | 6 |
is defined as | 6 |
position of the | 6 |
rise to a | 6 |
the window length | 6 |
related to a | 6 |
craig venter institute | 6 |
because of its | 6 |
able to replicate | 6 |
of herpes simplex | 6 |
fecal samples of | 6 |
diversity of sars | 6 |
in foxtail millet | 6 |
by the year | 6 |
coding region for | 6 |
to determine whether | 6 |
we have used | 6 |
in the latter | 6 |
to evaluate the | 6 |
state of the | 6 |
that they are | 6 |
mechanisms of genetic | 6 |
that the high | 6 |
high frequency of | 6 |
the position of | 6 |
it is thought | 6 |
to analyze the | 6 |
can be identified | 6 |
lethal mutagenesis of | 6 |
rates of rna | 6 |
infectious disease diagnosis | 6 |
scale sequencing of | 6 |
early stages of | 6 |
have been reported | 6 |
is thought that | 6 |
relative density of | 6 |
of the template | 6 |
diversity can be | 6 |
the malaria parasite | 6 |
it is difficult | 6 |
or absence of | 6 |
ancient pathogen dna | 6 |
the online version | 6 |
diversity within a | 6 |
on taxonomy of | 6 |
structure of poliovirus | 6 |
for template switching | 6 |
to be able | 6 |
of rna editing | 6 |
processing of the | 6 |
for viral replication | 6 |
the release of | 6 |
the origins of | 6 |
in the regions | 6 |
and invertebrate vectors | 6 |
bioinformatics resource centers | 6 |
available to the | 6 |
of the ires | 6 |
rna or dna | 6 |
of a large | 6 |
that the most | 6 |
to the scientific | 6 |
to have a | 6 |
and lack of | 6 |
viral genome is | 6 |
wide association study | 6 |
trait loci for | 6 |
grain protein content | 6 |
are currently being | 6 |
component of the | 6 |
in the meantime | 6 |
isolation and characterization | 6 |
in relation to | 6 |
multiplicity of infection | 6 |
the genome that | 6 |
to accelerate the | 6 |
nonhomologous rna recombination | 6 |
should also be | 6 |
to identify novel | 6 |
quality of the | 6 |
of rna molecules | 6 |
from the template | 6 |
a strain of | 6 |
the same or | 6 |
fidelity of the | 6 |
inside the cell | 6 |
of simple sequence | 6 |
been detected in | 6 |
that the two | 6 |
sequence of pseudomonas | 6 |
read and approved | 6 |
virus replication and | 6 |
of drug resistance | 6 |
central nervous system | 6 |
potential to be | 6 |
to be more | 6 |
in hepatitis c | 6 |
infl uenza a | 6 |
of the university | 6 |
as the first | 6 |
a method for | 6 |
a study of | 6 |
studies suggest that | 6 |
d p is | 6 |
that affect the | 6 |
coding region of | 6 |
sequence of yersinia | 6 |
southern china complete | 6 |
with an average | 6 |
according to their | 6 |
presence or absence | 6 |
set of genes | 6 |
to the viral | 6 |
borevitz et al | 6 |
fatty acid synthesis | 6 |
in the u | 6 |
and the host | 6 |
sfav a orf | 6 |
it could be | 6 |
annotation of the | 6 |
may be the | 6 |
genome from the | 6 |
translation of the | 6 |
of amino acids | 6 |
is not known | 6 |
a small number | 6 |
sequences from the | 6 |
of acute respiratory | 6 |
without prior knowledge | 6 |
were present in | 6 |
natural history of | 6 |
in vertebrate genomes | 6 |
found in all | 6 |
the recognition of | 6 |
of genes are | 6 |
conserved noncoding sequences | 6 |
version of the | 6 |
poliovirus can be | 6 |
betson et al | 6 |
of foreign genes | 6 |
the eradication of | 6 |
the loss of | 6 |
jx usa ak | 6 |
point of view | 6 |
is a prerequisite | 6 |
viruses have a | 6 |
with high accuracy | 6 |
vertebrates and invertebrates | 6 |
in kb sliding | 6 |
the orf of | 6 |
the microbial pan | 6 |
to have the | 6 |
of whole genome | 6 |
to support the | 6 |
in any of | 6 |
it is believed | 6 |
epidemic diarrhea virus | 6 |
considered agents of | 6 |
disease caused by | 6 |
shown in fig | 6 |
corynebacterium pseudotuberculosis strain | 6 |
it appears that | 6 |
be divided into | 6 |
belonging to different | 6 |
with the development | 6 |
be possible to | 6 |
for the treatment | 6 |
rest of the | 6 |
source of the | 6 |
infectious disease genomics | 6 |
of human influenza | 6 |
human parainfluenza virus | 6 |
of d p | 6 |
the total number | 6 |
was found in | 6 |
are important for | 6 |
the genomic diversity | 6 |
pertenue and endemicum | 6 |
the potential for | 6 |
human respiratory syncytial | 6 |
will not be | 6 |
a strategy to | 6 |
fly and worm | 6 |
the types of | 6 |
differences of ssrs | 6 |
are surrounded by | 6 |
been developed for | 6 |
information about the | 6 |
this may be | 6 |
in the order | 6 |
that cannot be | 6 |
comparative analyses of | 6 |
consists in the | 6 |
be exploited to | 6 |
sequences of two | 6 |
and to identify | 6 |
the strength of | 6 |
be transferred to | 6 |
online version of | 6 |
altmeyer et al | 6 |
and structure of | 6 |
would be the | 6 |
of pathogenicity islands | 6 |
the coding potential | 6 |
for each genome | 6 |
identification and characterization | 6 |
were associated with | 6 |
pallidum and pan | 6 |
tobacco mosaic virus | 6 |
with the advent | 6 |
detection and genotyping | 6 |
web server for | 6 |
the maximum likelihood | 6 |
of viral replication | 6 |
shed light on | 6 |
variation of viruses | 6 |
this indicates that | 6 |
characteristic of the | 6 |
from the host | 6 |
mutation in the | 6 |
consequence of the | 6 |
in the evolutionary | 6 |
respiratory tract infections | 6 |
production of a | 6 |
of the bacterial | 6 |
belongs to the | 6 |
rapid evolution of | 6 |
like to thank | 6 |
in the data | 6 |
in rna synthesis | 6 |
of the remaining | 6 |
at both ends | 6 |
methods such as | 6 |
was identified in | 6 |
indicating that the | 6 |
the complete mitochondrial | 6 |
was used as | 6 |
is a powerful | 6 |
proportional to the | 6 |
to be expressed | 6 |
considered as a | 6 |
the susceptibility to | 6 |
the public health | 6 |
time of writing | 6 |
sequence of staphylococcus | 6 |
using the same | 6 |
for analysis of | 6 |
the genomes and | 6 |
expected to be | 6 |
viral genomes is | 6 |
the host organism | 6 |
of the microbial | 6 |
part of this | 6 |
the common ancestor | 6 |
its role in | 6 |
to the same | 6 |
the concept of | 6 |
initial sequencing and | 6 |
the complete dataset | 6 |
interfering particles of | 6 |
the genome with | 6 |
was shown that | 6 |
a new host | 6 |
integrated into the | 6 |
a key role | 6 |
genetic diversity in | 6 |
to the virus | 6 |
revealed that the | 6 |
to generate the | 6 |
genome sequences from | 6 |
in a clinical | 6 |
the biology of | 6 |
wide association studies | 6 |
the genome in | 6 |
genome sequence is | 6 |
to target the | 6 |
complete mitochondrial genomes | 6 |
we would like | 6 |
shown that the | 6 |
subsp pallidum and | 6 |
of viruses in | 6 |
the genomes are | 6 |
virus to the | 6 |
have been the | 6 |
the fas ii | 6 |
found in a | 6 |
larger than the | 6 |
the molecular level | 6 |
of spontaneous mutation | 6 |
by more than | 6 |
as a consequence | 6 |
transmission of a | 6 |
of the sra | 6 |
of mutations that | 6 |
the present study | 6 |
mutation and selection | 6 |
a wealth of | 6 |
the locations of | 6 |
global burden of | 6 |
caused by the | 6 |
proteins in the | 6 |
the inserted gene | 6 |
away from the | 6 |
a reference genome | 6 |
while the other | 6 |
the organization of | 6 |
the genome d | 6 |
no competing interests | 6 |
was not the | 6 |
all strains of | 6 |
necessary for the | 6 |
one of these | 6 |
a single probe | 5 |
domain of the | 5 |
pilipenko et al | 5 |
the complete genomes | 5 |
etiologic agent of | 5 |
sites of recombination | 5 |
vary inversely with | 5 |
interaction with the | 5 |
the original variables | 5 |
a reference database | 5 |
to more than | 5 |
it cannot be | 5 |
the appearance of | 5 |
which do not | 5 |
some of which | 5 |
of coxsackievirus b | 5 |
sequences at the | 5 |
wide analysis of | 5 |
on the virus | 5 |
of genome sequence | 5 |
are available at | 5 |
of defective genomes | 5 |
which is not | 5 |
the stationary state | 5 |
the gene that | 5 |
as vectors for | 5 |
depth of coverage | 5 |
back to the | 5 |
a maximum of | 5 |
all the genomes | 5 |
for the generation | 5 |
protein content and | 5 |
of core genes | 5 |
associated with an | 5 |
adaptive value of | 5 |
the attenuation phenotype | 5 |
iii secretion system | 5 |
large amounts of | 5 |
and hepatitis c | 5 |
the gene expression | 5 |
the world health | 5 |
host range and | 5 |
and the emergence | 5 |
minimum number of | 5 |
human genome sequencing | 5 |
vivo and in | 5 |
evolutionary genetics analysis | 5 |
steps involved in | 5 |
complete viral genomes | 5 |
drought tolerance in | 5 |
associated with severe | 5 |
of the decade | 5 |
apart from the | 5 |
committee on taxonomy | 5 |
used in a | 5 |
the virus has | 5 |
suum and a | 5 |
genomes to be | 5 |
be found at | 5 |
organisms such as | 5 |
viral genome in | 5 |
virus genomes from | 5 |
within and between | 5 |
release of the | 5 |
world health organization | 5 |
contributes to the | 5 |
is regulated by | 5 |
the mode of | 5 |
the global distribution | 5 |
and they have | 5 |
rna virus populations | 5 |
recombination in a | 5 |
the two nasopharyngeal | 5 |
oryza sativa l | 5 |
that can infect | 5 |
the differences of | 5 |
in bacterial genomes | 5 |
the number and | 5 |
replacement of the | 5 |
affected by the | 5 |
set of sequences | 5 |
tend to have | 5 |
the genes that | 5 |
bacterium isolated from | 5 |
to be identified | 5 |
at the beginning | 5 |
coding and non | 5 |
in each of | 5 |
of the next | 5 |
th century ce | 5 |
well as other | 5 |
in the utr | 5 |
in the range | 5 |
percent of the | 5 |
conservation of the | 5 |
and high throughput | 5 |
have contributed to | 5 |
of the corresponding | 5 |
associated with fatal | 5 |
relationship between ssrs | 5 |
coding regions of | 5 |
a viral rna | 5 |
of gene families | 5 |
as a function | 5 |
are thought to | 5 |
in the breeding | 5 |
that the genetic | 5 |
increase in mutation | 5 |
focus on the | 5 |
a recent study | 5 |
single nucleotide resolution | 5 |
the incidence of | 5 |
evidence that the | 5 |
protein that is | 5 |
can be directly | 5 |
generation of a | 5 |
all analyzed viruses | 5 |
for synthesis of | 5 |
to assess the | 5 |
does not necessarily | 5 |
was shown to | 5 |
rates and frequencies | 5 |
in most cases | 5 |
subset of the | 5 |
generation sequencing data | 5 |
genome structures and | 5 |
the exon mutator | 5 |
growth of the | 5 |
reads per base | 5 |
there are also | 5 |
comparative sequence analyses | 5 |
toyoda et al | 5 |
was thought to | 5 |
the fi rst | 5 |
promising target for | 5 |
and there are | 5 |
form of the | 5 |
determination of the | 5 |
fixation of mutations | 5 |
provided by the | 5 |
as a first | 5 |
of genomic science | 5 |
that contains the | 5 |
the functional elements | 5 |
of sindbis virus | 5 |
evolutionary genomics of | 5 |
a new environment | 5 |
and it has | 5 |
viral genomes and | 5 |
was also found | 5 |
be the case | 5 |
but also the | 5 |
genetic information is | 5 |
on the human | 5 |
are not well | 5 |
of viruses is | 5 |
origin of ichnoviruses | 5 |
strains from the | 5 |
genetic variability and | 5 |
the nasopharyngeal samples | 5 |
the integrity of | 5 |
are susceptible to | 5 |
of the international | 5 |
the next generation | 5 |
been used for | 5 |
an even more | 5 |
they are not | 5 |
singh et al | 5 |
to ensure that | 5 |
illustrated in figure | 5 |
of population structure | 5 |
of foxtail millet | 5 |
the consequence of | 5 |
with each other | 5 |
nucleic acid sequences | 5 |
in the evolution | 5 |
which results in | 5 |
remain to be | 5 |
similar to each | 5 |
to characterize the | 5 |
section on evolution | 5 |
age of natural | 5 |
has contributed to | 5 |
equal to the | 5 |
molecular evolution of | 5 |
high level of | 5 |
there will be | 5 |
have now been | 5 |
viral genomes were | 5 |
viral rna genomes | 5 |
be part of | 5 |
and management of | 5 |
viral rna synthesis | 5 |
impact of the | 5 |
a better understanding | 5 |
a host cell | 5 |
of human genome | 5 |
genetic and biochemical | 5 |
niaid category a | 5 |
of nonreplicative rna | 5 |
has been successfully | 5 |
for invertebrate vector | 5 |
the sabin strains | 5 |
within the rna | 5 |
genome annotation pipeline | 5 |
the command line | 5 |
the processing of | 5 |
of genes from | 5 |
sequence data and | 5 |
a patient with | 5 |
the genetic code | 5 |
to tile the | 5 |
in which it | 5 |
basis of resistance | 5 |
that the genomes | 5 |
the evaluation of | 5 |
in the new | 5 |
the abundance of | 5 |
orf of the | 5 |
comparative genomics and | 5 |
been completely sequenced | 5 |
the genomic context | 5 |
of microbial species | 5 |
of murine hepatitis | 5 |
in the history | 5 |
from the national | 5 |
well as by | 5 |
that is similar | 5 |
the most commonly | 5 |
the presence or | 5 |
noted that the | 5 |
of which was | 5 |
in the sars | 5 |
each other and | 5 |
the mutation frequency | 5 |
in a separate | 5 |
for thousands of | 5 |
and d p | 5 |
consisting of the | 5 |
various types of | 5 |
to those of | 5 |
is referred to | 5 |
for this study | 5 |
the pathogenesis of | 5 |
of a complete | 5 |
may be able | 5 |
in cultured cells | 5 |
only of the | 5 |
is divided into | 5 |
is a web | 5 |
genome structural annotation | 5 |
the other strains | 5 |
that are difficult | 5 |
with the following | 5 |
from studies of | 5 |
coronavirus nonstructural protein | 5 |
for further analysis | 5 |
not lead to | 5 |
at the university | 5 |
genome sequencing has | 5 |
the viruses that | 5 |
more complex than | 5 |
the infection cycle | 5 |
lateral gene transfers | 5 |
differ from the | 5 |
could also be | 5 |
sequence of sv | 5 |
maintained in the | 5 |
crop improvement programmes | 5 |
african bovine rotaviruses | 5 |
possible that the | 5 |
will depend on | 5 |
jx tw tw | 5 |
of vesicular stomatitis | 5 |
of the latter | 5 |
academy of sciences | 5 |
does not contain | 5 |
and the human | 5 |
of the standard | 5 |
well as in | 5 |
gene finding algorithms | 5 |
of the d | 5 |
new insights into | 5 |
of the queue | 5 |
possible to assume | 5 |
the modencode project | 5 |
insertions or deletions | 5 |
the panarray algorithm | 5 |
hemorrhagic fever syndromes | 5 |
hidden markov model | 5 |
in any case | 5 |
of the cns | 5 |
of the correlation | 5 |
and phylogenetic analysis | 5 |
associated with disease | 5 |
discovery of novel | 5 |
a swarm of | 5 |
to maximize the | 5 |
and whole genome | 5 |
in fecal samples | 5 |
of all possible | 5 |
bacterial fatty acid | 5 |
to account for | 5 |
is designed to | 5 |
a fast and | 5 |
cq and hz | 5 |
review of the | 5 |
the percentage of | 5 |
close to the | 5 |
with the goal | 5 |
of the primary | 5 |
authors read and | 5 |
there are three | 5 |
the de novo | 5 |
from one template | 5 |
number of clusters | 5 |
of the s | 5 |
all types of | 5 |
the p region | 5 |
even if the | 5 |
were published in | 5 |
at the early | 5 |
of chagas disease | 5 |
or response to | 5 |
not required for | 5 |
it had been | 5 |
genes and the | 5 |
of viral and | 5 |
a broad range | 5 |
leads to a | 5 |
case of a | 5 |
by using the | 5 |
is the type | 5 |
absence of a | 5 |
with the human | 5 |
for the virus | 5 |
live attenuated vaccines | 5 |
in a variety | 5 |
at the national | 5 |
included in this | 5 |
cells with the | 5 |
look at the | 5 |
was carried out | 5 |
million years ago | 5 |
the genome into | 5 |
different modes of | 5 |
both of these | 5 |
to maintain the | 5 |
rna polymerase d | 5 |
is consistent with | 5 |
of the phage | 5 |
ssrs relative abundance | 5 |
of the complexity | 5 |
all forms of | 5 |
thousands of genes | 5 |
provide an overview | 5 |
the transition to | 5 |
than in the | 5 |
heterozygous and homozygous | 5 |
that the number | 5 |
the foreign gene | 5 |
consisting of a | 5 |
small fraction of | 5 |
the transcriptome map | 5 |
the internal ribosomal | 5 |
the purpose of | 5 |
the malaria mosquito | 5 |
studies of the | 5 |
of candidate genes | 5 |
function in the | 5 |
assembled from metagenomes | 5 |
microbial sequencing centers | 5 |
powerful tool to | 5 |
enabled us to | 5 |
is known to | 5 |
viruses belonging to | 5 |
the difference between | 5 |
families in the | 5 |
can be determined | 5 |
loss of infectivity | 5 |
of which is | 5 |
a viral infection | 5 |
are used for | 5 |
and the viral | 5 |
has resulted in | 5 |
number of studies | 5 |
canine distemper virus | 5 |
well as for | 5 |
applied to the | 5 |
and annotation of | 5 |