trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram frequency
the golgi apparatus595
of the golgi477
the plasma membrane423
the golgi complex416
the presence of409
in the golgi332
the cell surface304
the endoplasmic reticulum302
to the golgi278
the formation of268
in the presence248
the secretory pathway247
as well as204
in the er199
is required for174
to the plasma173
to the cell172
of the protein171
been shown to166
the role of159
a number of154
from the er151
to the er137
the cells were128
it has been128
the er and127
data not shown125
has been shown124
the cytoplasmic domain122
the absence of118
through the golgi118
of the er116
of the ga113
mouse hepatitis virus113
in addition to109
the golgi stack108
from the golgi103
and the golgi102
of the membrane101
the addition of100
proteins in the99
to the vacuole98
associated with the97
the e protein96
from the tgn95
shown to be95
the number of93
the site of91
the m protein91
in the absence90
vesicular stomatitis virus90
of the secretory90
involved in the89
the transmembrane domain89
the fact that89
of the cell86
structure of the85
localized to the85
part of the85
in the trans85
the transport of85
role of the84
transported to the80
required for the80
the localization of79
shown in fig79
in which the79
in the tgn79
cytoplasmic domain of78
present in the78
proteins to the76
domain of the74
in the endoplasmic74
that of the74
side of the74
of dpap a73
function of the71
guanine nucleotide exchange71
found to be71
exit from the70
one of the70
in contrast to70
from the endoplasmic70
in mammalian cells70
of the cells69
in the same69
herpes simplex virus69
the synthesis of69
has also been68
was found to68
the cytoplasmic tail68
analysis of the68
characterization of the67
endoplasmic reticulum and67
er and golgi67
of the n67
the case of67
transport to the67
cells infected with67
found in the66
some of the66
localization of the66
the function of66
and characterization of65
on the cell65
the rate of65
appears to be65
such as the64
golgi intermediate compartment64
due to the64
to the tgn63
at the cell63
formation of the63
m and s63
the effects of63
similar to that63
in the cytoplasmic63
region of the63
retained in the62
consistent with the62
proteins of the62
the distribution of62
with the golgi62
from the trans62
transmembrane domain of62
the er to62
in the case62
the amount of60
the b protein60
rough endoplasmic reticulum60
mutations in the60
a role in59
to that of59
the lumen of59
on the other59
appear to be59
golgi apparatus and58
at the plasma58
of the e58
are required for58
between the er57
proteins from the57
severe acute respiratory57
the other hand57
the effect of57
have been shown57
the possibility that56
role in the56
in order to56
as described above56
of the viral56
surface of the56
based on the55
are involved in55
in the secretory55
of vesicular stomatitis55
in the formation55
acute respiratory syndrome55
of mouse hepatitis54
the existence of54
the rough endoplasmic54
the s protein53
the structure of53
of the transmembrane53
nilsson et al53
in infected cells53
a variety of53
of membrane proteins53
to be a53
the assembly of52
presence of the52
is involved in52
most of the52
the n protein52
studies on the51
of the tgn51
back to the51
organization of the51
the surface of51
of the cytoplasmic51
of kre p51
has been suggested51
transport from the51
showed that the51
retention in the51
be involved in50
suggest that the50
in the cell50
the kre p50
regions of the50
derived from the49
of secretory proteins49
in the membrane49
in the cytoplasm49
cytoplasmic tail of49
is essential for49
to the trans48
the golgi stacks48
expression of the48
for min at48
er to golgi48
targeted to the48
as shown in47
the observation that47
changes in the47
at h p47
the early secretory47
have shown that47
semliki forest virus47
the er membrane47
of the m47
endoplasmic reticulum to47
to determine the47
of these proteins47
the majority of47
portion of the47
there is no46
er and the46
er to the46
and function of46
the sorting of45
components of the45
of the yeast45
african swine fever45
integral membrane protein45
into the er45
located in the45
face of the45
the appearance of45
protein in the45
a and b45
is consistent with45
out of the45
protein to the45
have been identified45
as a result45
hepatitis c virus44
in mdck cells44
transport of the44
was shown to44
respiratory syndrome coronavirus44
to the cis44
early secretory pathway44
assembly of the44
of newly synthesized43
appeared to be43
the budding compartment43
within the golgi43
a series of43
lumen of the43
of dpap b43
effect on the43
elements of the43
identification of a43
referred to as43
arf and arf43
the retention of43
members of the43
it is possible43
the context of43
spanning domain of43
domain of dpap43
vsv g protein42
has not been42
the golgi region42
the level of42
the endocytic pathway42
of the coronavirus42
h after infection42
swine fever virus42
the lumenal domain41
as described in41
schwartz et al41
in the context41
cells were fixed41
to be the41
tooze et al41
of the trans41
intracellular transport of41
the use of41
play a role41
the golgi network41
infectious bronchitis virus40
the er in40
materials and methods40
all of the40
the ability of40
results in the40
in the yeast40
was added to40
amino acid sequence40
it is not40
proteins that are40
through the secretory40
structure and function40
to determine whether40
domains of the40
a role for39
in hela cells39
the intermediate compartment39
from the cell39
remains to be39
of the endoplasmic39
nucleotide exchange factor39
indicate that the39
the host cell39
shown that the38
were treated with38
is possible that38
inserted into the38
distribution of the38
at the golgi38
was used to38
the golgi to38
activity of the38
adjacent to the38
the amino acid38
cov e protein38
have also been38
the accumulation of38
been implicated in37
of the arf37
the elementary unit37
nucleotide exchange factors37
the activity of37
secretory proteins in37
m s complexes37
golgi apparatus of37
of the virus37
amino acid residues37
of the proteins37
length of the36
the golgi and36
nothwehr et al36
occur in the36
been shown that36
golgi localization of36
cells were incubated36
residues in the36
association with the36
lumenal domain of36
responsible for the36
cisternae of the36
the rough er36
the yeast golgi36
the mechanism of36
the golgi cisternae36
to the pm36
thought to be36
according to the35
golgi to the35
the secretion of35
indicating that the35
of fhx p35
is thought to35
with s methionine35
be due to35
the movement of35
led to the35
well as the35
the biosynthesis of35
depending on the35
the release of35
to interact with35
of the p35
an inhibitor of34
the biogenesis of34
processing of the34
the organization of34
suggesting that the34
golgi complex and34
of the two34
presence of a34
at room temperature34
of the b34
of the mhv34
at the same34
in response to34
sequence of the34
is associated with33
regulated secretory pathway33
of the human33
added to the33
s d and33
the incorporation of33
change in the33
as described previously33
many of the33
the lipid bilayer33
signal in the33
in the lumen33
is sufficient for33
proteins into the33
the binding of33
of vsv g33
been suggested to33
to be involved33
followed by a33
the action of33
coronavirus e protein33
nature of the33
likely to be33
reticulum to the33
suggested that the33
end of the32
addition to the32
similar to those32
to the apical32
characterization of a32
with the plasma32
ferraro et al32
not required for32
plasma membrane and32
of the sars32
of ibv m32
roberts et al32
have not been32
of a membrane32
than that of32
budding from the32
and in the32
the idea that32
results suggest that32
transport through the32
is not clear32
contrast to the32
of the host32
on the cytoplasmic31
are present in31
for golgi retention31
properties of the31
of brefeldin a31
association of the31
the association of31
a result of31
for h at31
been suggested that31
the transfer of31
golgi retention signal31
schweizer et al31
the regulated secretory31
regulated secretory proteins31
polarized epithelial cells31
for min and31
the cell periphery31
of viral proteins31
integral membrane proteins31
the control of31
of the first31
were incubated with31
occurs in the31
the ga in31
of amino acids31
the process of31
jackson et al30
removal of the30
the activation of30
of a novel30
protein of the30
in the early30
to golgi membranes30
the vsv g30
in living cells30
of the fusion30
d and s30
is that the30
in the cells30
in vitro and30
golgi apparatus in30
surface expression of30
the end of30
localizes to the30
cells were washed30
that it is30
in cells infected30
the e glycoprotein30
amino acids of30
is dependent on30
accumulate in the30
the fusion protein30
in saccharomyces cerevisiae30
membrane of the29
there is a29
with the er29
the same time29
similar to the29
that the golgi29
study of the29
an integral membrane29
each of the29
are thought to29
is not known29
of these enzymes29
maturation of the29
that they are29
the gbf gea29
a membrane protein29
of the bilayer29
i and ii29
the tgn and29
cleavage of the29
of semliki forest29
cooper and bussey29
the nuclear envelope29
machamer et al29
the g protein29
cells in the29
activation of the29
of influenza virus29
the protein to29
the trans golgi28
membrane proteins in28
the expression of28
of infected cells28
analyzed by sds28
vesicles from the28
to the endoplasmic28
and s d28
proteins such as28
seems to be28
p in the28
of the lipid28
cells treated with28
demonstrated that the28
formation of a28
crystal structure of28
results were obtained28
e protein ic28
membranes of the28
proteins involved in28
related to the28
by brefeldin a28
stomatitis virus g28
the basis of28
mouth disease virus28
is mediated by28
were infected with28
revealed that the28
the development of28
fragmentation of the28
because of the28
has been demonstrated28
secretory pathway in28
an important role28
proteins have been28
the recruitment of28
were found to28
in cos cells27
the presence or27
disruption of the27
cells were treated27
golgi complex in27
understanding of the27
the production of27
site of budding27
is responsible for27
of the s27
of the c27
no effect on27
close to the27
of the peptide27
the cis golgi27
the center of27
thickness of the27
in this study27
morphology of the27
also been shown27
and golgi apparatus27
at the trans27
determined by the27
the regulation of27
the processing of27
known to be27
big and big27
cells were then27
of s d27
to the membrane27
in association with27
complex to the27
min of chase26
fused to the26
a family of26
component of the26
golgi apparatus is26
of vaccinia virus26
suggested to be26
of mm caffeine26
infected with mhv26
identification of the26
swift and machamer26
detected in the26
the kinetics of26
of the plasma26
are shown in26
inhibition of the26
interactions between the26
secretory proteins are26
for the retention26
the cytoplasmic face26
in the transport26
the importance of26
the fusion proteins26
dependent on the26
with respect to26
these results suggest26
interaction with the26
could not be26
terminus of the26
compartments of the26
golgi retention of26
similar results were26
is supported by26
with that of26
implicated in the26
localize to the26
at the tgn26
in the transmembrane26
expression of a26
cells were infected26
that there is26
the vacuolar membrane26
and that the26
secretory granules in26
been reported to26
has been reported25
of lysosomal enzymes25
the transmembrane segment25
parts of the25
of a protein25
location of the25
reticulum and the25
were shown to25
influenza virus hemagglutinin25
cells of the25
half of the25
at the cis25
of the early25
is necessary for25
the length of25
attached to the25
apical and basolateral25
from rat liver25
fact that the25
retention signal in25
this suggests that25
presence of bfa25
simplex virus type25
the percentage of25
insights into the25
the protein is25
of the rough25
presence or absence25
and processed for25
the results of25
for rain at25
the periphery of25
a golgi retention25
to the basolateral25
may also be25
localized in the25
interaction of the25
forms of the25
in some cases25
where they are24
important role in24
in terms of24
yeast golgi apparatus24
was determined by24
the efficiency of24
at least in24
an increase in24
member of the24
and has been24
plasma membrane proteins24
of progeny virions24
supported by the24
evidence that the24
the transmembrane and24
the replication complex24
reticulum and golgi24
the size of24
to study the24
suggests that the24
of the intermediate24
from the plasma24
evidence for a24
mediated by the24
to golgi transport24
membrane association of24
site of the24
the morphology of24
orci et al24
of the signal24
and chased for24
the viral genome24
to occur in24
addition of n24
cytoplasmic face of24
studies of the24
of the oligosaccharide24
of golgi proteins24
show that the24
did not affect24
cells were grown24
interact with the24
the tgn is24
the protein was24
are associated with24
of the major24
leads to the23
or absence of23
of the glycoprotein23
been found to23
to form a23
form of the23
be important for23
in polarized epithelial23
which can be23
of the same23
sorting in the23
of the total23
golgi membrane protein23
was found in23
results indicate that23
in control cells23
is known about23
the nature of23
de haan et23
vitro and in23
vps mutant cells23
constitutive and regulated23
golgi apparatus to23
is known to23
type i astrocytes23
e glycoprotein of23
the transmembrane domains23
the course of23
acts as a23
glycoproteins to the23
possibility is that23
immature secretory granules23
also known as23
coronavirus spike protein23
of secretory granules23
the golgi compartment23
retention of a23
golgi network of23
b and c23
mm caffeine at23
function in the23
by the addition23
have been described23
in epithelial cells23
has recently been23
of herpes simplex23
the treatment of23
haan et al23
but not the23
of this protein23
newly synthesized proteins23
localization to the23
the golgi membrane23
serve as a23
the identification of23
of the drug22
the location of22
but it is22
have been reported22
of the carbohydrate22
the regulated pathway22
be expected to22
the cytosolic domain22
of transmembrane proteins22
at the end22
residues of the22
a consequence of22
the removal of22
of proteins to22
that have been22
the budding of22
it is clear22
resulting in the22
very similar to22
and analyzed by22
due to a22
essential for the22
linked oligosaccharide chains22
level of the22
mutation in the22
more than one22
addition of the22
of the ic22
depends on the22
demonstrate that the22
not affect the22
the top of22
interaction between the22
the degradation of22
terminal amino acids22
transport of secretory22
in a membrane22
and membrane proteins22
is inhibited by22
of m and22
cytoplasmic domains of22
the study of22
the interaction between22
protein associated with22
as a consequence22
and processing of22
the interaction of22
the golgi is22
e protein is22
golgi complex is22
for the formation22
kre p tmd22
of the murine22
locker et al22
transmembrane segment of22
virus g protein22
it is likely22
of the three22
the golgi ribbon22
high levels of22
hydrophobic thickness of22
the transmembrane region22
relative to the22
and in vitro22
at the exit22
tang et al22
in cell culture22
to the transmembrane22
terminal domain of22
golgi cisternae and21
distinct from the21
were carried out21
in agreement with21
reggiori et al21
open reading frame21
golgi structure and21
for retention of21
that can be21
is similar to21
of proteins from21
to examine the21
rab and rab21
the exocytic pathway21
in animal cells21
roth et al21
possibility that the21
comparison of the21
well as in21
top of the21
is likely to21
these proteins are21
with the membrane21
sialic acid residues21
to the lysosome21
in vitro translation21
it is the21
delivery to the21
in this case21
some of these21
were used to21
transmembrane domains of21
that has been21
with each other21
protein is a21
protein transport and21
synthesis of the21
on the surface21
is regulated by21
to the formation21
levels of expression21
g for min21
at the er21
golgi complex to21
has been implicated21
of man ii21
of cell surface21
for golgi localization21
known about the21
has been proposed21
were grown in20
one or more20
saraste and kuismanen20
with the same20
interacts with the20
evidence for the20
and expression of20
it will be20
and plasma membrane20
knoops et al20
proteins through the20
effect of bfa20
m and e20
for viral replication20
the involvement of20
of the regulated20
conjugated goat anti20
are likely to20
in the present20
saraste and svensson20
that in the20
the inhibition of20
of arf and20
was supported by20
for review see20
the yeast secretory20
localization of a20
plasma membrane of20
membrane proteins are20
kindly provided by20
is likely that20
determination of the20
majority of the20
fusion of the20
yeast secretory pathway20
labeled with s20
by indirect immunofluorescence20
to be determined20
at the level20
in a post20
it is also20
resulted in the20
type ii membrane20
that the membrane20
retention of the20
as described by20
periphery of the20
at least one20
of coronavirus e20
proteins and the20
subunit of the20
along the secretory20
of the gc20
is required to20
and transport of20
forms of kexlp20
are transported to20
between the endoplasmic20
of the rer20
the membrane of20
be used to20
doms et al20
proteins may be20
may be a20
expressed in cos20
removed from the20
as previously described20
the extent of20
plasma membrane in20
to endo h20
important for the20
by the presence20
is clear that20
golgi membrane proteins20
the in vitro20
are responsible for20
is important for20
its retention in20
protein from the20
is found in20
the vaccinia virus20
a mechanism for20
the hydrophobic thickness20
its ability to20
but not in19
may play a19
domain of coronavirus19
required for golgi19
of the enzyme19
in golgi membranes19
between the two19
can also be19
were labeled with19
of golgi apparatus19
page and fluorography19
of severe acute19
the signal peptide19
membrane protein of19
a large number19
control of the19
step in the19
to be important19
with a half19
increase in the19
the induction of19
as determined by19
condensed secretory proteins19
consistent with this19
of golgi cisternae19
for membrane proteins19
in att cells19
the structure and19
the specificity of19
associated with a19
total number of19
ability of the19
into the medium19
the maturation of19
zhang et al19
in a cell19
case of the19
a final concentration19
targeting to the19
be required for19
it appears that19
of transition vesicles19
and in vivo19
maintenance of the19
a combination of19
ribophorin i molecules19
decrease in the19
in the medium19
at h after19
is targeted to19
the ii cytoplasmic19
and the plasma19
are known to19
it should be19
the replication of19
cell surface and19
are targeted to19
in the processing19
the integrity of19
washed three times19
in the sorting19
proteins destined for19
interactions with the19
acids of the19
ends of the19
under these conditions19
a member of19
er exit sites19
of the gm19
the generation of19
size of the19
coronavirus envelope protein19
the amino terminus19
of the a18
were applied to18
three times with18
absence of the18
of bfa on18
contribute to the18
of these structures18
a and a18
endosomes and lysosomes18
were incubated for18
large number of18
proteins and lipids18
of mdck cells18
in the pathway18
transmembrane proteins in18
the newly synthesized18
of a number18
not affected by18
within the er18
golgi ribbon formation18
in the plasma18
restricted to the18
final concentration of18
composition of the18
are important for18
enzymes involved in18
the total number18
see materials and18
synthesized in the18
in the ic18
p cytoplasmic tail18
its role in18
transit through the18
transport of proteins18
of the influenza18
signal in a18
in cells treated18
arf at the18
risco et al18
cell biol doi18
the exit of18
the catalytic domain18
incorporated into the18
but does not18
for min in18
of golgi enzymes18
j cell biol18
in the nucleus18
indicated that the18
of the vesicular18
transmissible gastroenteritis coronavirus18
structural and functional18
membrane spanning domain18
the basolateral surface18
was carried out18
it is unclear18
the same golgi18
there is evidence18
not appear to18
is localized to18
it is a18
the delivery of18
with brefeldin a18
in the rer18
to secretory granules18
and the tgn18
of cell biology18
data indicate that18
only in the18
presence of mm18
glycosylation of the18
from that of18
of rat liver18
a decrease in18
mhc class i18
the mechanisms of18
was present in18
a type ii18
to the vacuolar18
identification and characterization18
all of these18
trans golgi network18
observed in the18
little is known18
is due to18
be related to18
to play a18
of which are18
von willebrand factor18
gbf gea and18
bound to the18
the thickness of18
c and d18
coronavirus mouse hepatitis18
in the brain17
described in materials17
it can be17
has been observed17
the big sec17
by the fact17
to the surface17
showing that the17
conformation of the17
k killer toxin17
that there are17
fatty acyl chains17
in these cells17
on the golgi17
salanueva et al17
of the virion17
in patients with17
throughout the cytoplasm17
of the env17
and golgi complex17
the electron microscope17
activation of arf17
be present in17
kre p is17
the influenza virus17
specificity of the17
staining of the17
modification of the17
a change in17
cells were labeled17
for min with17
isolated from the17
on the basis17
may be important17
respect to the17
infected cells and17
apparatus to the17
is independent of17
had no effect17
the vesicular stomatitis17
and is required17
were transfected with17
of saccharomyces cerevisiae17
lead to the17
and then incubated17
golgi and the17
rottier et al17
deletion of the17
hepatitis virus strain17
in of the17
structure of a17
in the lipid17
much of the17
the constitutive pathway17
secretory pathway of17
of e protein17
of the budding17
domain of a17
a subset of17
are necessary for17
been proposed to17
of the sec17
the viral envelope17
fuse with the17
hela cells were17
those of the17
to be localized17
is not required17
vacuolar protein sorting17
are found in17
found that the17
in protein transport17
regulation of the17
have been found17
of membrane traffic17
features of the17
of kex p17
luminal er proteins17
density lipoprotein receptor17
to note that17
we conclude that17
golgi membranes and17
membrane proteins of17
not essential for17
sufficient for golgi17
the ends of17
corresponding to the17
replication and assembly17
wide range of17
of the mouse17
together with the17
the ph domain17
to reach the17
translocation of the17
do not have17
subcellular localization of17
the cytoplasm and17
were maintained in17
delivered to the17
of the vacuolar17
fusion proteins were17
believed to be17
vennema et al17
the membranes of17
function as a17
the rer and17
between these two17
cytosolic domain of17
in materials and17
the golgi membranes17
are unable to17
at least three17
of arf proteins17
the dpap a17
sites in the17
growth factor receptor16
of cells with16
resulted in a16
depend on the16
insight into the16
binding of the16
the signal peptidase16
been localized to16
and big sec16
for the golgi16
to determine if16
protein sorting in16
small g proteins16
transported through the16
to changes in16
proteins in a16
may be the16
the nlrp inflammasome16
amino terminus of16
of regulated secretory16
golgi network and16
of african swine16
er in the16
associate with the16
potent inhibitor of16
is shown in16
griffiths et al16
biosynthetic protein transport16
into the cytoplasm16
the ga and16
necessary for the16
used in this16
in the c16
host immune response16
of intracellular transport16
seen in the16
signal peptidase cleavage16
at a dilution16
under the control16
role in golgi16
and cytoplasmic domains16
the liquid crystalline16
can be seen16
domain in the16
when the cells16
one of these16
to the n16
the sequence of16
the fusion of16
is sufficient to16
different cell types16
the cell cycle16
indicates that the16
involvement of the16
and may be16
when expressed in16
integrity of the16
is determined by16
destined for the16
by electron microscopy16
from the membrane16
low et al16
functions as a16
protein was found16
in the regulation16
proteins at the16
of the g16
used as a16
fusion with the16
after min of16
membrane traffic and16
released from the16
the culture medium16
in many cases16
be associated with16
described in the16
encoded by the16
the rsv env16
that the cytoplasmic16
of plasma membrane16
burke et al16
a wide range16
mechanism of action16
in membrane traffic16
the first amino16
their ability to16
bos et al16
fhx p in16
linked to the16
concluded that the16
to a final16
proteins do not16
inhibitor of the16
low levels of16
of the most16
golgi fragmentation in16
hydrophobic length of16
complex in the16
low density lipoprotein16
each of these16
retrograde transport of16
role for the16
have been proposed16
of the elementary16
to the e16
are consistent with16
a dilution of16
are derived from16
env gene product16
li et al16
for s d16
of the amino16
cells were transfected16
to the cytoplasmic16
have demonstrated that16
proteins within the16
on the plasma16
from the rer16
proteins and their16
membrane proteins from16
of secretory vesicles16
functional analysis of16
membrane proteins and16
of type i16
has been identified16
a set of15
between the rough15
is able to15
in the cytosol15
and sufficient for15
to be transported15
model for the15
the crystal structure15
transport of vesicular15
the apical membrane15
proteins accumulate in15
of the pathway15
aspects of the15
glycosylation in the15
the envelope proteins15
export from the15
of the lumenal15
is not a15
to the yeast15
the membrane spanning15
after infection with15
formed in the15
the finding that15
were incubated in15
performed as described15
this work was15
recruited to the15
transported from the15
that the ii15
of the nh15
or in the15
be found in15
the m and15
of the molecular15
as in the15
the viral membrane15
in combination with15
of the mannose15
a model for15
of protein secretion15
been proposed that15
the restrictive temperature15
been used to15
the host immune15
for h and15
a highly conserved15
of att cells15
endo h treatment15
mouse hepatitis coronavirus15
branch of the15
the golgi localization15
may not be15
the cytoplasmic side15
fraction of the15
identified as a15
of endoplasmic reticulum15
the lack of15
resides in the15
concentrated in the15
with those of15
required for its15
of the kre15
has been the15
the cytoplasmic and15
of action of15
early and late15
of budding of15
docking and fusion15
in the viral15
amino acid sequences15
redistribution of golgi15
were subjected to15
addition of galactose15
virus strain a15
the onset of15
were fixed and15
is the only15
in the budding15
with the anti15
presence of caffeine15
the result of15
viral replication and15
is composed of15
the conclusion that15
has been made15
produced by the15
to be required15
cytoplasmic tails of15
serves as a15
virions in the15
and resuspended in15
cells grown on15
of a golgi15
of the molecule15
apical or basolateral15
necessary and sufficient15
the severe acute15
a component of15
the cytoplasmic tails15
the early golgi15
be responsible for15
the bulk of15
at the c15
with endo h15
m protein is15
in the field15
of protein transport15
the targeting of15
marker for the15
be interesting to15
in close proximity15
are able to15
viral membrane proteins15
were analyzed by15
strand rna viruses15
and e proteins15
that at least15
stomatitis virus glycoprotein15
into the lumen15
transport between the15
unfolded protein response15
center of the15
be located in15
by the observation15
and the other15
leading to the15
stages of the15
of these two15
be able to15
the murine coronavirus15
have been observed15
route to the15
the present study15
of a coronavirus15
epidermal growth factor15
of ras l15
there was no15
is transported to15
incubated for h15
within the cytoplasmic15
and it is15
is believed to15
to form the15
of the other15
cells in culture15
to inhibit the15
of arf in15
is present in15
exchange factor gbf15
the oligosaccharide chain15
a monoclonal antibody15
dalcq et al15
steps in the15
would be expected15
these results indicate15
of addition of15
residues within the14
in this paper14
in this review14
and inhibition of14
used in the14
the medial golgi14
also involved in14
of golgi membranes14
is capable of14
has been known14
the default pathway14
transport of semliki14
different types of14
golgi matrix protein14
the er is14
of the cellular14
cell surface expression14
marie et al14
effect of the14
have been isolated14
plutner et al14
cell biology of14
were obtained from14
in a number14
are localized to14
secretory pathway and14
reggiori and klionsky14
by addition of14
leu leu leu14
of at least14
distributed throughout the14
independent of the14
the significance of14
so that the14
the apical surface14
determine whether the14
balch et al14
oligosaccharide chains of14
transport and sorting14
purification and characterization14
area of the14
from golgi to14
observation that the14
the loss of14
at the nonpermissive14
exchange factor for14
the levels of14
of the cd14
the construction of14
been observed in14
an essential role14
linked oligosaccharides of14
appearance of the14
be mediated by14
in the synthesis14
have been suggested14
with regard to14
and the cells14
and of the14
glc man glcnac14
subunits of the14
intracellular localization of14
of mammalian cells14
of the organelle14
can be used14
the concentration of14
in the perinuclear14
there was a14
the prototype serum14
transport in the14
was not affected14
of the mutant14
lysosomal membrane proteins14
were fixed with14
is based on14
ii cytoplasmic tail14
viral rna replication14
present on the14
darby canine kidney14
glucosidase i and14
baby hamster kidney14
transmembrane ot helices14
g protein of14
after their synthesis14
with the m14
to show that14
found on the14
the product of14
used at a14
protein transport from14
to accumulate in14
a recent study14
of the iicr14
give rise to14
in the first14
for h with14
of vps p14
to the endocytic14
into secretory granules14
expressed on the14
the arf gefs14
a potent inhibitor14
gea and big14
derived from a14
it may be14
the two proteins14
wang et al14
only a few14
to the same14
product of the14
localization of p14
tgn to the14
compartment of the14
incubated in the14
biosynthesis of the14
shown to inhibit14
in the biosynthesis14
and targeting of14
segment of the14
sorting of the14
was detected in14
are essential for14
two types of14
considered to be14
b and a14
the first step14
in vivo and14
are retained in14
although it is14
the small gtpase14
and s proteins14
the ic and14
in yeast and14
any of the14
of membrane protein14
eluted from rca14
membrane topology of14
is the major14
loss of the14
plasma membrane protein14
protein that is14
to the nucleus14
not to be14
mutational analysis of14
rous sarcoma virus14
differences in the14
this is the14
to the cytoplasm14
be attributed to14
central nervous system14
it would be14
be noted that14
of the wild14
ga in processes14
secretory pathway is14
treated with bfa14
and dpap a14
the ectodomain of14
of er buds14
belov et al14
work was supported14
the intracellular transport14
a amino acid14
flow from the14
through er and14
of a particular14
in er to14
our understanding of13
the position of13
outside of the13
to have a13
and secretion of13
and sialic acid13
does not appear13
of the insulin13
methionine for min13
proposed that the13
expressed in the13
that the transmembrane13
the cytoplasm to13
and sec ml13
none of the13
of interest to13
for the er13
has been found13
the ability to13
the nonpermissive temperature13
is restricted to13
amino acids in13
of resident proteins13
traffic in the13
on the role13
the er retention13
the sars coronavirus13
processing in the13
whether or not13
in the liquid13
the stem region13
opstelten et al13
possible that the13
transmembrane region of13
reticulum to golgi13
gefs and gaps13
of m protein13
regulated by the13
data suggest that13
multidrug resistance protein13
protein has been13
membrane proteins to13
retention of p13
received for publication13
baguena et al13
of the hydrophobic13
along with the13
membrane protein sorting13
the requirement for13
and then chased13
not yet been13
retinas were collected13
resulting in a13
wheat germ agglutinin13
targeting of the13
of the complex13
is linked to13
these data indicate13
in vps mutant13
the gm activator13
movement of the13
at g for13
studies have shown13
en route to13
difference between the13
to this end13
g ml of13
studies indicate that13
at the restrictive13
in the latter13
view of the13
studies showed that13
of a large13
antibodies specific for13
absence of a13
and stained with13
and vps p13
as shown by13
as judged by13
results in a13
dpap a is13
isolation and characterization13
incubated for min13
this may be13
in revised form13
of glycoproteins and13
proteins are sorted13
the coronavirus mouse13
not in the13
derivatives of ras13
there are no13
the s subunit13
traffic from the13
and maintenance of13
one possibility is13
the functions of13
of viral dna13
and secretory proteins13
of the rat13
and in revised13
replication and transcription13
late golgi compartment13
result in the13
the carboxy terminus13
residues on the13
vesicular transport of13
to identify the13
even though the13
we have previously13
vesicles in the13
is critical for13
corse and machamer13
piper et al13
note that the13
gleeson et al13
for the sorting13
is caused by13
caused by the13
protein exit from13
this is not13
is the most13
budding of progeny13
indicated by the13
protein and the13
the samples were13
ml of bfa13
the golgl apparatus13
consistent with a13
play an important13
ceacam a cells13
was used at13
of the genome13
in the rough13
rather than the13
of ganglioside biosynthesis13
injected intravitreally with13
within the cell13
to give a13
and incubated with13
of a single13
should be noted13
of viral glycoproteins13
of p o13
liquid crystalline phase13
indirect immunofluorescence microscopy13
yu et al13
vesicles to the13
the iicr chimera13
domain of tgn13
effects of the13
of the rsv13
infected cells were13
of the high13
form of s13
events in the13
to the periphery13
a complex with13
are required to13
involved in protein13
by the endoplasmic13
of st is13
of the vsv13
and the er13
secretory and membrane13
to be present13
sequence in the13
the copi coat13
the cis side13
rsv env gene13
of cells expressing13
from each other13
at the n13
proteins on the13
rate of transport13
was digested with13
the sec domain13
the env gene13
the gene encoding13
in the cytosolic13
compared with the13
that the protein13
carried out by13
and properties of13
the exit from13
vesicles and the13
the tgn in13
translocation across the13
and golgi membranes13
binding to the13
of the ap13
and identification of13
be part of13
from er to13
intracellular transport and13
class i and13
in more detail13
which in turn13
the analysis of13
rate of bulk13
that is required13
rough er and13
the hydrophobic length13
membranes in the13
protein with the13
of enveloped viruses13
was replaced by13
were able to13
which have been13
obtained from the12
were obtained with12
explanation for the12
pancreatic acinar cells12
the high mannose12
characteristics of the12
human immunodeficiency virus12
roles in the12
oh r a12
the transferrin receptor12
to increase the12
of the gene12
to the protein12
as indicated by12
of arf gefs12
directly to the12
be divided into12
allowed us to12
as part of12
gm and gm12
and activation of12
were collected for12
exclusively in the12
that appear to12
and from the12
mechanism by which12
delivery of the12
motif in the12
next to the12
the protein in12
m protein was12
of the polarized12
described for the12
golgi exclusion zone12
of proteins into12
compared to the12
and function in12
different from that12
membrane glycoproteins to12
average number of12
that the kre12
for virus replication12
in some cells12
of coronavirus mhv12
kex p and12
and in cells12
a and c12
entry into the12
in the number12
fuller et al12
signals in the12
of the envelope12
the virus factory12
in cultured cells12
in the assembly12
was isolated from12
for the treatment12
of the various12
the golgi structure12
for transport to12
to be an12
the secretory granule12
be required to12
machamer and rose12
of the transport12
of the interaction12
a guanine nucleotide12
into the membrane12
the signal anchor12
and g ml12
acid sequence of12
domains of these12
and fusion of12
a secretory protein12
plasma membrane by12
for the presence12
domain of p12
kre p was12
structures of the12
a protein that12
by means of12
at reduced temperature12
of patients with12
that newly synthesized12
the proteins were12
was used as12
the a protein12
the form of12
kre p cytoplasmic12
golgi compartments and12
of vesicular transport12
of the different12
be important in12
proteolytic processing of12
some of which12
of the stacked12
the unfolded protein12
of the lipids12
of both the12
of golgl apparatus12
the golgi in12
of golgi structure12
protein was not12
in support of12
in both the12
transmembrane and cytoplasmic12
the ergic and12
hela cells expressing12
cytoplasmic side of12
linked oligosaccharide chain12
the formation and12
across the golgi12
novoa et al12
the golgi exclusion12
both of these12
to be secreted12
as an integral12
pfeffer and rothman12
carboxy terminus of12
it seems likely12
located on the12
operate in the12
of viral membrane12
chinese hamster ovary12
recognized by the12
sorting at the12
to test whether12
isolation of a12
manuscript submitted for12
the tgn to12
coronavirus infectious bronchitis12
within the secretory12
submitted for publication12
of the endocytic12
the redistribution of12
ii transmembrane region12
with triton x12
which has been12
molecular mass of12
murine coronavirus spike12
is accompanied by12
residue transmembrane domain12
the basis for12
a conformational change12
medial golgi enzymes12
golgi apparatus the12
but not for12
has shown that12
disassembly of the12
association of m12
required for efficient12
s d mutant12
the conformation of12
condensing secretory proteins12
support for the12
raymond et al12
golgi structure formation12
high molecular weight12
wilcox et al12
and localization of12
protein secretion in12
sensitive to bfa12
directly from the12
receptors in the12
the method of12
processed for immunofluorescence12
to be due12
of m s12
of the catalytic12
that interact with12
an accumulation of12
of bulk flow12
man ii was12
in ergic golgi12
of a new12
through the er12
a protein of12
gives rise to12
effects of pdmp12
for h in12
of mhc class12
bulk flow from12
rat liver golgi12
from a post12
bound form of12
protein with a12
terminal region of12
of the sorting12
mhc class ii12
to localize to12
enzymes in the12
in intact cells12
mutants of the12
accumulated in the12
as we have12
structural maturation of12
a direct role12
the rer to12
retrograde transport from12
were then washed12
arf guanine nucleotide12
in spite of12
the he protein12
traffic between the12
of the retention12
is evidence that12
recent studies have12
class ii arfs12
of the gradient12
endo h digestion12
has been used12
the late golgi12
stranded rna viruses12
glycoproteins from the12
involved in golgi12
mutant forms of12
of these molecules12
of the prohormone12
the herpes simplex12
not inhibit the12
the secretory granules12
protein required for12
changes of the12
form of a12
connected to the12
er proteins are12
agreement with the12
exposed on the12
in the cis12
the er lumen12
of p and12
secretory vesicles from12
to the replication12
class e compartment12
short et al12
cytoplasmic tail and12
and adjacent to12
can serve as12
kd protein associated12
seem to be12
from the rough12
it does not12
in the ergic12
many of these12
cisternae and the11
during the cell11
to generate the11
and intracellular transport11
essentially as described11
to provide a11
transport and processing11
golgi membranes to11
terminal residues of11
but did not11
a critical role11
have been implicated11
could be detected11
accumulation in the11
effects of bfa11
the discovery of11
and fhx p11
large arf gefs11
is important to11
the yeast tgn11
graham and emr11
the structural proteins11
access to the11
human chorionic gonadotropin11
the low density11
to the cytosol11
of this pathway11
that the two11
of monensin on11
part of a11
were expressed in11
for the first11
amount of the11
carried out in11
defined by the11
of this review11
of the dpap11
of the manuscript11
implying that the11
after bfa treatment11
likely that the11
bulk of the11
the average number11
of membrane trafficking11
has been localized11
important in the11
effects on the11
the basolateral membrane11
this compound is11
for subcellular fractionation11
rise to the11
the endo h11
in which a11
the normal l11
wessels et al11
mediated arf activation11
by virtue of11
the cell in11
does not affect11
affected by the11
nm in diameter11
the detection of11
to the budding11
were washed with11
that the presence11
in eukaryotic cells11
was retained in11
protein does not11
thickness of a11
used for the11
in intracellular transport11
these structures are11
collected for subcellular11
does not prevent11
corresponds to the11
of eukaryotic cells11
be derived from11
specify golgi retention11
linked oligosaccharides are11
at least two11
may be related11
of cathepsin d11
sorting to the11
of the luminal11
thin sections of11
the mhv infection11
in this way11
its association with11
the cell type11
not result in11
and the membrane11
of each of11
the er or11
the cytoplasmic domains11
from the pvc11
a drug that11
of some of11
gosert et al11
the extent to11
with the cell11
and sorting by11
munro and pelham11
domains in the11
reside in the11
that the proteins11
golgi to er11
is a type11
transmembrane domain is11
the potential to11
abeijon et al11
a patient with11
in table i11
endoplasmic reticulum membrane11
member of a11
for transport of11
downstream of the11
of the process11
oligosaccharides of the11
sorting by the11
we propose that11
golgi transport vesicles11
presence of an11
an example of11
at the site11
golgi membranes in11
been identified in11
branches of the11
retention of golgi11
which they are11
the signal for11
membrane and secretory11
that ibv m11
secretory proteins and11
that the c11
oligomerization of a11
with the exception11
colley et al11
that kre p11
cooper and stevens11
gillingham and munro11
at the top11
the hydrophobic domain11
of the mammalian11
the fxfxd motif11
a type i11
rate at which11
of the t11
may be involved11
small immature vesicles11
protein is not11
action of the11
proteins associated with11
ion channel activity11
recruitment of the11
to the early11
consists of a11
followed by the11
golgi stack and11
and subjected to11
were added to11
major histocompatibility complex11
golgi apparatus cisternae11
virus membrane glycoproteins11
at the endoplasmic11
position of the11
act as a11
retrieval from the11
viral rna synthesis11
on golgi membranes11
protein is required11
in live cells11
coronavirus rna replication11
golgi mannosidase i11
followed by sds11
saraste et al11
to serve as11
of the hybrid11
in conjunction with11
the same buffer11
gene product is11
shows that the11
on the trans11
small amount of11
localization of ibv11
cells transfected with11
have previously shown11
golgi apparatus a11
from the isg11
of the large11
of the syncytia11
for its retention11
wills et al11
was performed as11
the intracellular localization11
take place in11
dissection of the11
the first site11
role of a11
proteins during the11
s and he11
essential role in11
on the same11
of chondroitin sulfate11
from the nucleus11
of coronavirus el11
of epithelial polarity11
a class of11
raises the possibility11
the rate at11
have been detected11
chen et al11
in the second11
b protein is11
its interaction with11
and cell surface11
the trafficking of11
min and chased11
seems likely that11
kim et al11
h after transfection11
the origin of11
golgi proteins into11
was performed by11
truncated forms of11
of protein sorting11
the exception of11
to a single11
and membrane traffic11
been known to11
at in the11
close proximity to11
to define the11
treated with brefeldin11
ergic golgi membranes11
in the amount11
to be located11
within and adjacent11
of the nuclear11
yeast saccharomyces cerevisiae11
golgi matrix proteins11
in the pellet11
s methionine and11
sigma chemical co11
a mutation in11
fhx p was11
is not essential11
for hr at11
then incubated with11
forest virus membrane11
a bilayer of11
the enzyme that11
to those of11
ergic and golgi11
shown by the11
ribophorins i and11
the viral replication11
labeled for min11
in the medial11
of the cytoplasm11
monoclonal antibody against11
in different cell11
membrane traffic in11
peripheral membrane protein11
type ii astrocytes11
secretion of proteins11
that the first11
the ph of11
of the oligomer11
of guanine nucleotide11
were incubated at11
copii and copi11
in polarized cells11
journal of cell11
the yeast vacuolar11
the wild type11
compartment to the11
big sec proteins11
a marker for11
of the ca11
presence of castanospermine11
which may be11
have indicated that11
a major role11
a regulated secretory11
the retention signal11
of the normal11
biogenesis of lysosomes11
included in the11
was fused to11
golgi stacks and11
which is a11
rather than a11
of ribophorin i11
min in the11
the isolation of11
associates with the11
to the other11
is blocked by11
cell surface in11
topology of the11
with or without11
in the host11
the ii transmembrane11
discussed in the11
golgi transport in11
griffiths and simons11
efficiency of the11
sorted to the11
stages in the11
aridor et al11
consisting of the11
has led to11
of gangliosides in11
was inserted into11
rer to the11
to the ergic11
is derived from11
is in the10
transport of a10
result of the10
for the synthesis10
detected at the10
are regulated by10
of the nlrp10
the field of10
heath et al10
the sseg mutant10
first site of10
m protein of10
membrane traffic between10
virus m protein10
of the sample10
orientation of the10
a multiplicity of10
insertion of the10
in the protein10
quality control in10
of the gbf10
context of a10
and sorting of10
the membrane surface10
each time point10
domain and the10
of golgi membrane10
the behavior of10
is no evidence10
the e r10
were found in10
surrounded by a10
inhibition of protein10
the constitutive and10