bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram frequency
vesicular stomatitis504
stomatitis virus455
influenza virus188
infected cells180
protein synthesis138
respiratory syndrome129
host cell120
cell lines118
hela cells109
virus infection101
type i97
antiviral activity97
immune responses95
ebola virus93
neutralizing antibodies74
ebov gp72
west nile71
recombinant vesicular70
viral mrnas70
plasma membrane66
enveloped viruses65
ifit mice65
virus replication65
vsv infection64
nile virus62
virus glycoprotein61
syndrome coronavirus61
amino acid60
vero cells60
pseudotyped virus57
viral envelope57
room temperature56
cell surface56
vaccinia virus55
cell culture54
rvsv vectors54
severe acute54
acute respiratory54
host protein54
cellular mrnas53
immunodeficiency virus53
neutralizing antibody52
virus particles52
spike protein52
virus type51
vectors expressing51
cell line51
viral rna50
viral replication50
gp pseudotyped49
cells infected49
antiviral activities49
herpes simplex49
gene expression48
aug codon48
host mrnas48
treated cells47
vaccinated mice47
immune response46
vaccine vectors45
human immunodeficiency45
fever virus44
viral proteins44
i ifn43
monoclonal antibodies43
influenza viruses43
vsv replication42
simplex virus42
leukemia virus41
mammalian cells41
viral infection41
middle east39
neutralization assay39
cotton rats39
cord uid39
rna polymerase39
doc id39
described previously39
measles virus38
previously described38
acid sphingomyelinase38
avian influenza38
porcine reproductive38
east respiratory38
hemorrhagic fever37
viral mrna37
cell entry36
er buds36
viral protein36
epithelial cells36
envelope proteins36
virus entry35
congo hemorrhagic35
recombinant vsv35
amino acids35
well plates34
export complexes34
syndrome virus34
golgi complex34
membrane fusion33
wt mice33
cell fusion33
bhk cells32
positive control32
transmembrane domain32
cap binding31
host translation31
lentiviral vectors31
tetherin antagonism30
murine leukemia30
host shutoff29
pseudotyped viruses29
pseudotyped hiv29
viral glycoproteins29
days post29
wt vsv29
sindbis virus29
endoplasmic reticulum29
vsv xn29
polysome association29
positive cells29
matrix protein29
protein expression29
stomatitis viruses28
virus vectors28
negative control28
neutralization test28
vaccine vector28
mdck cells27
virus envelope27
cytoplasmic tail27
structural proteins27
aug codons27
rvsv vector27
rna virus27
transcriptional activity27
cells expressing26
viral genome26
antibody responses26
viral entry26
intercat ifn26
host proteins26
membrane proteins26
live ebov26
body weight26
treated virions25
lipid bilayer25
rna viruses25
viral infections24
target cells24
cellular immune24
thermo fisher24
prok treated24
based assay24
replication competent24
tumor cells24
cell types24
sarcoma virus24
pseudotyped vsv24
previous studies23
performed using23
vsv rna23
virus mrnas23
insect cells23
recombinant vsvs23
mosaic virus23
inhibitory effect23
serum samples23
monoclonal antibody23
viral translation23
nucleotide sequence23
culture medium22
secondary structure22
proteolytic cleavage22
mrna cap22
tissue culture22
fusion protein22
binding protein22
cov infection22
virus glycoproteins22
envelope protein22
antibody titers22
animal models22
electron microscopy22
mm tris22
highly pathogenic22
sialic acid22
ifnar mice22
gfp expression21
pseudotyped vectors21
plaque assay21
molecular weight21
based vaccine21
weight loss21
fisher scientific21
nonhuman primates21
initiation factor21
envelope glycoprotein21
cotton rat21
retroviral vectors21
high levels20
serial dilutions20
mediated antiviral20
bovine serum20
antibody response20
sendai virus20
neutralization assays20
vector expressing20
semliki forest20
membrane protein20
cell responses20
present study20
western blot20
transduction efficiency20
infectious virus20
open reading20
nervous system20
dependent manner20
central nervous19
current study19
clinical trials19
first time19
com scientificreports19
virus rna19
surface proteins19
leader sequence19
coronavirus spike19
transfected cells19
virus assembly19
viral particles19
cell death19
test using19
infectious diseases19
post infection19
using vsv19
attenuated vesicular18
day pi18
protein kinase18
uninfected cells18
cytopathic effect18
mouse model18
lethal challenge18
significant differences18
dmem containing18
gene delivery18
determine whether18
pfu ml18
detected using18
expression vector18
reading frames18
single dose18
kindly provided18
animal cells18
forming units18
results indicate18
per well18
tetherin expression18
taken together18
vsv virions18
goat anti18
envelope glycoproteins18
feline ifn18
forest virus18
sars coronavirus17
three times17
cellular mrna17
control group17
virus expressing17
disease virus17
start site17
cell membrane17
virus infectivity17
reaction mixture17
final concentration17
reading frame17
reporter gene17
guinea pigs17
golgi apparatus17
whole virions17
whether doxorubicin17
viral gene17
emc virus17
oligomer formation17
sucrose gradients17
control groups17
results demonstrate17
signaling pathway17
neutralisation assay17
mers gfp17
virus titers17
pseudotypes bearing17
gene therapy17
expression levels17
upstream aug17
antiviral effect17
virus production16
virus vaccine16
virus neutralisation16
stranded rna16
infected rn16
prime boost16
washed twice16
translation initiation16
ebov neutralisation16
graphpad prism16
expression plasmids16
live virus16
green fluorescent16
highly attenuated16
cov neutralizing16
animal model16
fluorescent protein16
i interferon16
statistically significant16
may also16
neutralisation assays16
independent experiments16
host range16
coding sequence16
baculovirus vectors16
column chromatography16
gold particles16
host cells16
antibody titer16
buffered saline16
buds per15
viral titers15
rna replicates15
total number15
important role15
statistical significance15
restriction sites15
gp gp15
mg ml15
nipah virus15
protease inhibitor15
cytoplasmic domain15
fusion activity15
viral spread15
cd cd15
mg kg15
rabbit anti15
trypsin treatment15
mediated immune15
vectors pseudotyped15
latently infected15
dromedary camels15
viral vectors15
vaccine protects15
recombinant feifn15
type vsv15
gxxxg motif15
promoted ripa15
rous sarcoma15
luciferase activity14
novel coronavirus14
pathogenic avian14
innate immune14
antiviral agents14
containing fbs14
fetal bovine14
influenza virions14
cell protein14
surface glycoprotein14
two different14
cell lysates14
nucleocapsid protein14
autographa californica14
resistant oligomer14
sigmodon hispidus14
sialic acids14
protective immune14
flow cytometry14
serially diluted14
specific antibody14
coronavirus infection14
spectrum antiviral14
specific antibodies14
doxorubicin inhibits14
ripa activity14
challenge infection14
respiratory syncytial14
ifn signaling14
infectious vsv14
creative commons14
epithelial cell14
error bars14
genomic rna14
total cytoplasmic14
complete protection14
syncytial virus14
mice immunized14
associated reads14
virus strains14
also inhibited14
ng ml14
strand rna13
animal care13
western blotting13
three independent13
expression plasmid13
newly synthesized13
human glioblastoma13
pseudoparticle neutralization13
vsv vrp13
human cells13
er membrane13
rna synthesis13
intact cells13
gg ml13
rabies virus13
gene transfer13
also showed13
metabolic labeling13
vsv genome13
approved drugs13
resulting residue13
bat cell13
pbs containing13
stem cells13
dk services13
determined using13
virus particle13
using live13
glioma cells13
transcription unit13
immune system13
vaccine development13
host mrna13
cancer stem13
gel electrophoresis13
vaccine based13
significantly higher13
ribosomal subunits13
significant difference13
transcription promoter13
live attenuated13
infected wt13
cellular proteins13
cell viability13
attenuated rvsv12
authentic sars12
cov spike12
replication cycle12
culture supernatant12
messenger rna12
airway epithelial12
binding factor12
saudi arabia12
encephalitis virus12
viral genes12
initiation sites12
terminator codon12
previous study12
washed three12
viral membrane12
culture supernatants12
post transfection12
guinea pig12
glycosylation sites12
complemented vsv12
cells transfected12
prrsv olot12
cell proteases12
investigate whether12
vsv pseudotypes12
expressing cells12
viral surface12
vsv particles12
time points12
sense rna12
pseudotyped lentiviral12
erk signaling12
exclusion zone12
hepatitis virus12
renal epithelial12
results suggest12
sucrose cushion12
antiviral response12
golgi retention12
translational machinery12
gene encoding12
table i12
negative controls12
fold serial12
virus challenge12
vaccine candidates12
zoonotic viruses12
promote ripa12
golgi exclusion12
secondary antibodies12
virus matrix12
kidney cells11
reverse genetics11
protease inhibitors11
specific immune11
proteins identified11
packaging system11
protect mice11
protective efficacy11
feline leukemia11
hispidus cell11
live mers11
like particles11
medium containing11
human sera11
standard plaque11
virus groups11
attenuated vsv11
infected group11
binding domain11
lysis buffer11
feline interferon11
cell monolayers11
mm edta11
human tetherin11
cells grown11
recombinant baculovirus11
binding proteins11
based neutralization11
resident proteins11
biosafety level11
analyzed using11
strongly inhibited11
protects mice11
lethal dose11
bars indicate11
virus recombinants11
antiviral action11
data suggest11
previously reported11
silica gel11
vsv vector11
chromatography using11
expressing hiv11
primary antibodies11
two proteins11
doxorubicin treatment11
inhibited vsv11
caspase activity11
vsv vectors11
laboratory animals11
mouse igg11
increased polysome11
treated mice11
haemorrhagic fever11
virus mrna11
neutralization tests11
cells showed11
sucrose gradient11
first aug11
coat protein11
term protection11
new jersey11
gel column10
specific cell10
vaccinated animals10
neuronal necrosis10
antiviral state10
empty vector10
signal peptide10
secondary antibody10
polyacrylamide gel10
single immunization10
specific ifn10
cells per10
boosted group10
binding site10
heat shock10
metabolically labeled10
also inhibits10
viral membranes10
infected cell10
virus hemagglutinin10
gp ecto10
entry inhibitors10
boost vaccination10
virus titer10
baculovirus display10
prrsv envelope10
infected mice10
conjugated goat10
virus proteins10
eukaryotic ribosomes10
exchange vectors10
fluorescence microscope10
specific igg10
rna levels10
attenuated recombinant10
unpublished data10
suicide gene10
bd biosciences10
previously shown10
cell cultures10
structural components10
mice per10
based vaccines10
infectious particles10
translational control10
spanning domain10
genes encoding10
free medium10
thymidine kinase10
promoting ripa10
mrna synthesis10
virus infections10
er surface10
decreased polysome10
i glycopeptides10
export complex10
vp gene10
ge copies10
first position10
lentiviral vector10
tyrosine kinase10
widely used10
lumenal domain10
sars vaccine10
genome replication10
using anti10
newcastle disease10
free extracts10
culture plates10
mm nacl10
fd vsv10
vrp expressing10
ifit isg10
antigen expression9
infected hela9
heterologous animal9
irf mutant9
foreign antigen9
led us9
animal viruses9
late viral9
type ii9
serial sections9
public health9
stirred solution9
reverse transcription9
total protein9
tested whether9
throughput screening9
mouse hepatitis9
significantly stronger9
influenza virion9
authors declare9
mrna levels9
treated animals9
ripa branch9
infected ifit9
virus preparations9
stacking gel9
ethyl acetate9
plasma membranes9
vsv glycoprotein9
two independent9
broad spectrum9
viral diseases9
recombinant feline9
vsv recombinant9
serological assays9
adverse effects9
dendritic cells9
mers coronavirus9
apoptotic pathway9
surface area9
tetherin counteraction9
highest dilution9
surface display9
rna genome9
initiation factors9
vsv mrnas9
virus infected9
different cell9
restrictive temperature9
proteins found9
similar results9
cell tropism9
cell membranes9
significant reduction9
sequence analysis9
lymphocytic choriomeningitis9
budding profiles9
min chase9
units ml9
vsv proteins9
clinical signs9
low ph9
class ii9
random distribution9
biological activities9
serum dilution9
national institute9
viral fusion9
results showed9
small amount9
prototypic rvsv9
cell shut9
tripartite leader9
peptide pool9
high titer9
virus strain9
foreign gene9
leaky scanning9
reovirus mrnas9
virucidal activity9
life cycle9
total rna9
cellular protein9
enveloped rna9
neutralising antibodies9
rna replication9
cap methylation9
ebov challenge9
using recombinant9
hamster kidney9
translational regulation9
choriomeningitis virus9
competent vector9
evd survivor9
different viruses9
vectors transduced9
plasmid dna9
indirect immunofluorescence9
post challenge9
rvsv expressing9
commons license9
nuclear envelope9
mm sodium9
viral budding9
well plate9
driven entry9
leader rna9
recent studies9
initiator codon8
control cells8
expression system8
luciferase reporter8
high throughput8
intraperitoneally injected8
fusion proteins8
rna expression8
counting method8
different concentrations8
mdbk cells8
doxorubicin activates8
virus fusion8
class i8
dependent rna8
female balb8
type virus8
rbl cells8
human coronavirus8
gfp vlps8
mm hepes8
inhibitory effects8
aids vaccine8
gfp fluorescence8
mrna translation8
lassa fever8
cells untreated8
initiation site8
penicillin streptomycin8
expressing vsv8
old mice8
capsid protein8
peripheral sites8
essential medium8
mrna transcription8
particles per8
reverse transcriptase8
elevated temperature8
liquid nitrogen8
neutralizing activity8
plasmids encoding8
sds resistance8
induced cell8
proteolytic activation8
antigenic determinants8
proteins associated8
proteolytic digestion8
spike glycoproteins8
humoral immune8
ha spike8
given i8
surface glycoproteins8
cell signaling8
brain tissues8
human infection8
virus disease8
tetherin antagonist8
assay using8
coding region8
high concentrations8
dmem supplemented8
batfluav surface8
ifit protein8
spike glycoprotein8
expressing gml8
indiana serotype8
mem medium8
log pfu8
rvsv vaccine8
extracellular adp8
polyhedrosis virus8
vector system8
pseudotypes harboring8
influenza vaccine8
virucidal effect8
mouth disease8
virus neutralization8
cell receptor8
foreign glycoproteins8
recombinant vaccine8
horseradish peroxidase8
virus systems8
viral loads8
cells using8
growth factor8
neutralizing epitopes8
nhei restriction8
regulatory factor8
gfp cells8
golgi transport8
phosphate buffered8
cells treated8
pi treatment8
cells via8
ebov infection8
virus spread8
per infected8
inflammatory responses8
reduction neutralization8
brain cells8
binding medium8
rnp complexes8
herpes virus8
vsv spread8
single amino8
prok treatment8
vsv antibody8
using graphpad8
doxorubicin inhibited8
bee venom8
statistical analysis8
mrna expression8
zaire ebolavirus8
using lipofectamine8
specific antiviral8
test whether8
extensively washed8
growth kinetics8
alfalfa mosaic8
linked immunosorbent8
virus using8
reduced pressure8
consecutive sections8
glycosyl side8
viruses including8
vectored vaccine8
hiv protease8
crystal violet8
immunoprecipitated using8
virus genome8
specific proteins8
internal aug8
glycoprotein exchange8
competitive binding8
low dose8
personal communication8
infected insect8
electron microscope8
institutional animal8
may provide8
competent vsv8
per cell8
end point8
human coronaviruses8
vsvs expressing8
cell plasma8
intranasal inoculation8
viral vector8
hela cell8
acid residues8
encoded gfp8
parainfluenza virus8
vectored vaccines8
pyrvinium pamoate8
receptor binding8
tubular elements8
transmembrane serine8
thermofisher scientific8
weeks post8
challenge experiments8
doxorubicin promoted8
competent vesicular8
sphingomyelinase activity8
plaque forming7
virus gp7
virus adsorption7
previous reports7
efficient translation7
rlr stimulation7
cycle vectors7
total volume7
bone marrow7
mean sd7
protein bands7
yersinia pestis7
ge healthcare7
polyacrylamide gels7
innate immunity7
within days7
chikungunya virus7
mammalian cell7
effective aids7
log tcid7
virus attachment7
equal volume7
based vectors7
uranyl acetate7
ifit proteins7
abl tyrosine7
membrane components7
pancreatic acinar7
inhibit virus7
restricted mutant7
protein inhibits7
ha na7
cytoplasmic abundance7
cellular receptor7
cellular membrane7
infection without7
virus pseudotypes7
virus replicon7
er export7
ifn response7
lentiviral pseudotyped7
second bud7
use committee7
immune cell7
translational efficiency7
wide range7
hours post7
sodium dodecyl7
bat cells7
vaccine approach7
dna vaccines7
growth medium7
clinical studies7
biologically active7
data demonstrated7
previous work7
ribosome binding7
virus budding7
avian leukosis7
virus vector7
resistant oligomers7
kda protein7
mouse anti7
vector based7
egfp expression7
purified virus7
buffer containing7
yellow fever7
ch cl7
nrk cells7
biological activity7
log increase7
transgene expression7
vsv titers7
intranasal infection7
large oligomer7
planar projection7
clinical trial7
vitro models7
cancer cells7
infected mouse7
cytopathic effects7
expression vectors7
host shut7
vsv neutralizing7
cellular genes7
viral nucleocapsid7
virus structural7
three different7
mutant lxxxl7
purified virions7
codon usage7
fresh culture7
doxorubicin also7
cells challenged7
recombinant human7
viral polypeptides7
cell type7
day post7
natural host7
generated using7
hepatocellular carcinoma7
export sites7
vsv infected7
mediated cell7
treated samples7
national institutes7
lg ml7
tumor growth7
tcid ml7
endosomal membranes7
spike rbd7
studies will7
encephalomyocarditis virus7
major structural7
golgi region7
dna viruses7
smaller polysomes7
antiviral effects7
surface density7
humoral response7
protein may7
host factors7
stimulated genes7
may reflect7
provides complete7
viral pathogenesis7
lipid composition7
kinase gene7
less efficiently7
stop codon7
inhibits host7
pancreatic cancer7
cycle vsv7
major enu7
sensitive mutants7
firefly luciferase7
recombinant vaccinia7
proteolytic processing7
schwannoma cells7
expressing glycoproteins7
virus vaccines7
measured using7
challenge virus7
kcal mol7
protein composition7
adenovirus type7
spectral counts7
highly susceptible7
viral infectivity7
induced protein7
plaque assays7
different vsvs7
vivo studies7
ha protein7
normal brain7
vsv indiana7
examine whether7
neutralizing titers7
nonsegmented negative7
prism software7
facs analysis7
right panel7
ht cells7
virus membrane7
knockout mice7
second aug7
small molecule7
virus recombinant7
major surface7
early mrnas7
purified using7
using hexane7
soluble expression7
binding assay7
persistent infection7
united states7
marburg virus7
permissive temperature7
neuraminidase activity7
aqueous solution7
crystal structure7
olfactory bulbs7
external surface7
poliovirus mrna7
african green7
proteomic analysis7
animal experiments7
scientificreports www7
disease control7
inhibit viral7
fluorescence microscopy7
best studied7
results demonstrated7
negative strand7
enu start7
gml oligomer7
mice developed7
retroviral vector7
human pathogens7
purified recombinant7
pcr amplification6
internal proteins6
infection results6
log scale6
green monkey6
elicit robust6
mice showed6
gives rise6
minimum essential6
expression systems6
californica nuclear6
cap equivalent6
host rna6
whether vsv6
microplate reader6
early region6
gfp infected6
ebov vaccine6
ace interaction6
body temperature6
essential role6
wild type6
induced ifit6
transmission electron6
vsv pseudotype6
may occur6
vaccine production6
chain reaction6
without affecting6
lethal ebola6
data indicate6
incubated overnight6
throughput screen6
two methods6
medium supplemented6
intramuscular injection6
vivo gene6
containing viruses6
i ifns6
mediated tetherin6
high degree6
molecular probes6
entry requires6
frog virus6
independent replicates6
cellular membranes6
wheat germ6
attenuation strategies6
expressing ebovgp6
fresh medium6
competent construct6
antiviral properties6
different regions6
cap structure6
acid sequences6
distilled water6
intranasal vaccination6
bat influenza6
shock protein6
neutralization antibodies6
baby hamster6
neutralization antibody6
foreign proteins6
baculovirus expression6
wsn strain6
dimensional organization6
animal studies6
gene products6
either vsv6
associated virus6
mice expressing6
protective immunity6
innate antiviral6
expressing hafl6
red blood6
entry assay6
internal initiation6
ebola vaccine6
codon occurs6
cem gfp6
average number6
high generation6
colorless oil6
glass coverslips6
including vsv6
igg titers6
avian sarcoma6
standard deviation6
poliovirus rna6
infection experiments6
likely due6
oncolytic vesicular6
virus encephalitis6
hiv env6
inhibits viral6
competing interests6
designated pvsv6
attenuated vsvs6
mutant virus6
life technologies6
rvsv hiv6
virus input6
cd expression6
directly inhibit6
virus ankara6
enriched membrane6
may contribute6
cells plated6
cytoplasmic fraction6
sequence homology6
intranasally infected6
vaccinated group6
particle release6
standard deviations6
glycoprotein species6
ml domain6
also used6
virus pseudotype6
fold increase6
previously published6
mass spectrometry6
inhibits vsv6
allantoic fluid6
table iii6
nuclear polyhedrosis6
units per6
single cycle6
vectors showed6
potent anti6
per ixm6
viruses expressing6
significantly increased6
primary structure6
gp mab6
virus grown6
vitro antiviral6
human primates6
cleavage sites6
influenza viral6
ni affinity6
virus protein6
chandipura virus6
one mrna6
prrsv proteins6
assays using6
lethal ebov6
completely inhibited6
ace receptor6
shutoff mechanism6
based pseudotyped6
polymerase chain6
review see6
molecular weights6
acid sequence6
surface expression6
functional receptor6
co atmosphere6
calculated using6
complete medium6
open access6
gene ontology6
stem cell6
peer review6
intracranial inoculation6
hemagglutinating activity6
polysome fractions6
efficient transduction6
modified vaccinia6
dose vaccination6
viral mutant6
inhibit translation6
trypan blue6
provide evidence6
sulfur atom6
virus stock6
plasma samples6
adenovirus early6
family members6
either one6
directed expression6
antiviral drug6
nonstructural proteins6
values obtained6
sample types6
current status6
one might6
major groups6
candidate vaccine6
cov neutralization6
translational capacity6
mumps virus6
ebovgp gene6
studies revealed6
mediated entry6
complete nucleotide6
examined whether6
virus species6
pet cats6
per se6
baculovirus surface6
ml recombinant6
membrane glycoproteins6
distantly connected6
fold lower6
transmembrane domains6
tests using6
cd low6
protein cytoplasmic6
ii transmembrane6
infect cells6
viral titer6
much lower6
factor eif6
progenitor cells6
purified mab6
intranasal vsv6
restriction factor6
six times6
results obtained6
spike proteins6
kinase inhibitor6
nv model6
metabolically radiolabeled6
moloney murine6
cell receptors6
pg ml6
total er6
peptide pools6
mouse serum6
flag epitope6
polypeptide chains6
molecular mass6
closely related6
supplementary table6
reporter genes6
plaque reduction6
also found6
see materials6
antibody directed6
oncolytic virus6
results show6
active site6
tris ph6
interferon omega6
statistical analyses6
specific neutralizing6
overall decline6
nm gold6
treatment inhibited6
ms ms6
kidney epithelial6
gammaretroviral vectors6
like receptor6
following challenge6
hal proteins6
associated coronavirus6
ammonium chloride6
immunosorbent assay6
small molecules6
tobacco mosaic6
experimental animal6
deficient mice6
world health6
entry driven6
san diego6
embryonic fibroblasts6
additional transcription6
based ebola6
findings suggest6
ribonucleic acid6
nasal epithelial6
vaccine candidate6
mean surface6
enveloped virus6
type mice6
cleavage site6
extracellular domain6
pseudotype entry6
blot analysis6
beta interferon6
jak stat5
different vsv5
iptg concentration5
strong humoral5
purinergic receptors5
transduced tumor5
cell proteins5
olot strain5
signal pathway5
inhibits virus5
mem i5
gene translocations5
serum albumin5
high virus5
following vsv5
two groups5
replicon particles5
viral genomes5
many viruses5
glycoprotein gene5
neutralization titers5
prrsv antigens5
investigated whether5
inhibit vsv5
herpes viruses5
animal welfare5
virion samples5
partial inhibition5
feline immunodeficiency5
response curves5
free systems5
lateral diffusion5
recombinant expressing5
study showed5
immunofluorescence assay5
acinar cells5
genome organization5
restriction site5
major viral5
ml streptomycin5
continuous cell5
respiratory tract5
vsv leader5
signal sequence5
health organization5
cell gene5
tested cells5
converting enzyme5
crispr cas5
equine encephalitis5
assay kit5
sfcs splenocytes5
major capsid5
highly significant5
phosphorylation sites5
lassa virus5
hiv gag5
oligosaccharide side5
proven protease5
accession number5
imaging system5
vsv replicons5
antiviral genes5
well tolerated5
rhabdoviridae family5
two additional5
pandemic influenza5
termination codon5
downstream site5
either immediately5
graphpad software5
virus pathogenesis5
phenotypic mixing5
cytokine responses5
randomly chosen5
new subtypes5
viral suspensions5
human cd5
virus assays5
feline infectious5
zika virus5
study endpoint5
aug triplets5
carbohydrate composition5
liver diseases5
background level5
integral membrane5
ti rotor5
soluble forms5
prrsv infection5
prokaryotic soluble5
covalently linked5
simian immunodeficiency5
tetherin antagonists5
using previously5
cells ml5
camp epac5
infectious virion5
nude rats5
years ago5
side chain5
viral envelopes5
viruses infecting5
several viruses5
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cellular entry5
genomic cdna5
two new5
interfering rna5
wnv infection5
mouse survival5
ebovgp vector5
mcias using5
purified vsv5
several studies5
globin mrna5
studies demonstrate5
pseudotype particles5
pikfyve kinase5
entry efficiency5
optimal induction5
eukaryotic initiation5
inhibit host5
evaluated using5
will likely5
vai rna5
animals developed5
coli strains5
vaccine approaches5
tag ni5
induced inhibition5
protective humoral5
cchfv challenge5
copi coats5
protein transport5
virusinfected cells5
optimal antiviral5
cause severe5
dna replication5
viral systems5
binding domains5
scanning mechanism5
escherichia coli5
concentric shells5
hind limb5
antibody positive5
receptor molecule5
secretory pathway5
coronavirus disease5
cell extracts5
see section5
neutralization epitopes5
fold higher5
like receptors5
intracellular trafficking5
vaccinated pigs5
observations suggest5
among different5
several approaches5
protects nonhuman5
safety studies5
uitro translation5
hiv type5
animal species5
plaque formation5
genomic dna5
immunodiffusion protocol5
different recombinant5
induction conditions5
cholesterol transporter5
empty plasmid5
virus isolates5
wide variety5
competent cells5
transfected bhk5
foreign protein5
congo haemorrhagic5
dmem medium5
groups compared5
hcg antibody5
protein complex5
derived buds5
reticulocyte lysate5
antiviral defense5
infectious peritonitis5
vsv platform5
er bud5
plasmid pvsv5
sugar ring5
ifn system5
may result5
viral glycoprotein5
recombinant virus5
bearing pseudotypes5
model system5
monkey kidney5
experimental vaccines5
ripa contributes5
two distinct5
potential antiviral5
serum antibodies5
viral neuraminidase5
side chains5
intranasally vsv5
results led5
human population5
defective interfering5
drug screening5
plasmid encoding5
elispot responses5
gene product5
control serum5
regional foci5
serial dilution5
antiviral function5
cleavage products5
rat glioma5
mice infected5
cytoplasmic mrna5
encoding feifn5
many different5
effective therapeutic5
recognition receptors5
radiolabeled vsv5
vero cell5
days pi5
also induced5
using intercat5
pc cells5
kinase inhibitors5
ng hiv5
like cells5
biochemical studies5
imaged using5
rhesus macaques5
human clinical5
data presented5
rvsv ebov5
inhibits infection5
baculovirus displaying5
even though5
parental vsv5
clinical evaluation5
intracellular compartments5
reg cells5
pseudotyped baculovirus5
untreated cells5
final volume5
adenovirus mrnas5
oncolytic vsv5
capped mrnas5
research institute5
hybridoma supernatant5
specific activity5
immune serum5
therapeutic agents5
wt vol5
sino biological5
evd survivors5
phylogenetic tree5
molecule inhibitors5
tail length5
cd cells5
neutralising activity5
ripa activators5
novel antiviral5
brain tumors5
using two5
small mammals5
highly effective5
vectors will5
nhp nv5
free dmem5
ncov usa5
uninfected rn5
acid substitutions5
apilimod blocks5
ma cells5
infection conferred5
reduced tetherin5
tissue tropism5
within vtcs5
cells date5
complementary sequences5
fruit bat5
normal shutoff5
binding sites5
competent vaccine5
dodecyl sulfate5
using pseudotyped5
plasmid system5
homologous animal5
activate ripa5
gtp restricted5
structural protein5
bars represent5
well culture5
ifn action5
per ml5
virus growth5
clinical development5
vsv particle5
tissue sections5
favorable context5
disease following5
atcc ccl5
deep sequencing5
volume ratio5
vsv adsorption5
vesicle budding5
average rlu5
activate irf5
stat pathway5
virus pseudotyped5
vsv expressing5
alkaline phosphatase5
affinity column5
conjugated secondary5
potent protective5
structural component5
cytotoxic effects5
mice exhibited5
functional characterization5
derived vesicles5
ml penicillin5
previously demonstrated5
prompted us5
phase i5
serine proteases5
hypertonic stress5
simian virus5
clinically proven5
natural reservoir5
vsv activity5
quantified using5
cauliflower mosaic5
macromolecular synthesis5
fourth transcription5
induced apoptosis5
glioma model5
way anova5
virion surface5
mouse pems5
cells well5
pseudotypes using5
invasive areas5
rbd protein5
neuraminic acid5
andes virus5
highly efficient5
proteins encoded5
rapid protection5
associated mrna5
pathogens including5
optimized vaccine5
washed six5
aug triplet5
studies using5
cd ifn5
human monoclonal5
cell growth5
expression using5
eight hours5
neutralized vsv5
transiently transfected5
protease treatment5
novel virus5
observed using5
hong kong5
rat schwannoma5
transcription stop5
proteins expressed5
incorporated efficiently5
peptide cleavage5
virus may5
inhibit acid5
performed mcias5
signaling competent5
plos one5
encoded proteins5
glycoproteins expressed5
naturally occurring5
new england5
membrane structure5
marburg viruses5
diarrhea virus5
heterologous challenge5
cell duplication5
fluorescent vlps5
sw ti5
approximately kda5
polysome fraction5
subcellular localization5
endosomal ph5
input virus5
strong immune5
infectious centres5
limb paralysis5
liquid chromatography5
induction time5
golgi compartments5
transfection medium5
polyclonal rabbit5
i interferons5
viral disease5
commons attribution5
encode proteins5
adenovirus va5
natural infection5
laboratory animal5
transitional region5
transcription gradient5
infectious units5
ifit genes5
cellular infection5
internal surface5
control vsv5
sequence reads5
gene induction5
malignant glioma5
expressing egfp5
mediated neutralization5
competent rvsv5
induced irf5
prrsv gp5
mediated activation5
experimental conditions5
mouse monoclonal5
membrane receptors4
certain bat4
thigh muscle4
nuclear margin4
showed similar4
may interact4
ifn receptor4
polymerase protein4
reduced vsv4
inoculated intranasally4
one based4
severe respiratory4
modified eagle4
irf transcriptional4
arabian peninsula4
fixation conditions4
zaire ebola4
protein exchange4
might mediate4
rabbit papillomavirus4
vector laboratories4
uracil nucleoside4
venezuelan equine4
decreasing amounts4
virus binding4
human transmission4
asked whether4
highly invasive4
potentially zoonotic4
coomassie staining4
cell cytoplasm4
virus life4
protease tmprss4
sodium ions4
new world4
following lethal4
elevated temperatures4
human viruses4
polymerase ii4
vsv vaccine4
effect inhibition4
transmembrane region4
cell volume4
apoptotic cells4
coronavirus receptor4
imatinib inhibits4
surface antigen4
therapeutic effect4
tmprss cells4
studies reported4
neutral ceramidase4
cell biol4
slightly lower4
virus maturation4
small interfering4
robust cd4
protective potential4
igg response4
monitored daily4
glycoprotein precursor4
santa cruz4
humanely euthanized4
nahco aqueous4
human influenza4
conducted using4
antibodies specific4
interferon regulatory4
mammalian expression4
docking scores4
nonstructural protein4
cytotoxic concentration4
doubly infected4
th fractions4
puc vector4
detection system4
blue exclusion4
antagonize tetherin4
black beetle4
sanger sequencing4
findings indicate4
nucleotide sequences4
vsv replicates4
virus titre4
expressing either4
complement control4
genbank accession4
sand flies4
porcine tetherin4
protein interactions4
antibody neutralization4
budding sites4
structural polypeptides4
nitrocellulose membranes4
cd apc4
thank also4
convalescent sera4
using flowjo4
comparable growth4
vaccine virus4
virus sv4
infectious viral4
significantly reduced4
one type4
also activate4
vitro studies4
two glycoproteins4
markers nestin4
empty expression4
associated influenza4
prepared using4
embryonated chicken4
tumor areas4
new york4
increasing amounts4
dead cells4
positive tumor4
vaccines protect4
singlestranded rna4
high susceptibility4
exhibited potent4
gradient sedimentation4
dependent protein4
mouse bmdms4
hsv type4
signaling pathways4
hybridoma cell4
translational modifications4
encoded vsv4
mean cell4
activate hal4
novel vesicular4
study day4
cellular gene4
virion formation4
strand viruses4
hybridoma antibodies4
vesicular carriers4
treated groups4
complete sequence4
will need4
culture models4
cell functions4
biological functions4
initiating cells4
detect mers4
dna damage4
therapeutic efficacy4
ts vsv4
mice inoculated4
vector attenuation4
antibody specific4
major protein4
ascites tumor4
studies described4
mice succumbed4
proteins required4
hours prior4
performed according4
protective effect4
blocks infection4
distributed throughout4
forming assay4
cell biology4
start signal4
hemagglutinin provides4
triplicate wells4
cell targeting4
blood cells4
carboxyl terminus4
native pr4
slow shaking4
vsv pathogenesis4
electrophoretic mobility4
containing mm4
capsid proteins4
colorless sticky4
histopathological examination4
highly enriched4
alpha beta4
structural glycoproteins4
differential inhibition4
thank dr4
three groups4
large numbers4
cell supernatant4
different amounts4
host species4
forward primer4
control animals4
leukaemia virus4
days without4
fluc activity4
glycoproteins may4
stable expression4
experimental vaccine4
hl nl4
gradient centrifugation4
vsv mrna4
luciferase assay4
starting dilution4
goose erythrocytes4
cellular tropism4
temperature overnight4
genetic information4
kos strain4
free translation4
ideal balance4
mature virus4
distinct mechanisms4
group also4
therapeutic options4
replication deficient4
eagle medium4
adherent cells4
molecular mechanisms4
times higher4
coronavirus associated4
data show4
influenza vaccines4
purinergic signaling4
coxsackie virus4
sequence encoding4
significantly inhibited4
seven distinct4
study provides4
vsv pseudotyped4
possible explanation4
alternative method4
field isolates4
histocompatibility complex4
buds detected4
strong neutralizing4
small fraction4
tg ml4
vectors based4
model using4
type virions4
intranasal route4
higher expression4
pilot studies4
using monoclonal4
using primers4
human cell4
adaptive immune4
family rhabdoviridae4
one another4
protein provides4
infecting bhk4
viral rnp4
cell supernatants4
limiting membrane4
control pnhs4
gene expressing4
cytoplasmic membranes4
combination therapy4
future studies4
infectious dose4
control mice4
dipeptidyl peptidase4
antigen presentation4
immunized mice4
cytosine nucleoside4
virus stocks4
immunofluorescence microscopy4
restricts viral4
least two4
also obtained4
phlebotomine sandflies4
detectable antibody4
remain polysome4
enhanced green4
positive way4
two genes4
whole virion4
either wt4
vsv protein4
resulting plasmid4
mediate entry4
activate batfluav4
cmv promoter4
hafl vaccines4
treated vsv4
deleterious effects4
host interactions4
approximately nm4
technical replicates4
transmembrane protein4
novel arthropod4
foreign antigens4
vsv genes4
murine retroviruses4
brome mosaic4
receptor cd4
table ii4
confocal microscopy4
promising vaccine4
blocked formation4
brain tumor4
clinical applications4
ethanol administration4
neuraminidase activities4
zebov infection4
polymerase complex4
ten days4
trypsin inhibitor4
novel viruses4
membrane glycoprotein4
interferon system4
hep cells4
may represent4
vsv neutralisation4
interferon genes4
virus thymidine4
dilution factor4
mouse embryonic4
organic layer4
vaccine efficacy4
activates ripa4
assay based4
gp fusion4
ns proteins4
ifn production4
vaccine viruses4
temperature sensitive4
solubilized either4
truncated form4
membrane domains4
borne encephalitis4
virus induced4
budded baculovirus4
vaccine platform4
using vesicular4
pol gene4
efficient recovery4
translation efficiency4
cycle replication4
molecular cloning4
insect virus4
promoting compounds4
codon optimized4
luis enjuanes4
using pseudotype4
activating compounds4
max nm4
human anti4
rvsv genome4
mitsunobu reaction4
considered significant4
camp plays4
respiratory disease4
newly generated4
survival rate4
glycoprotein expression4
ifn antiviral4
several different4
mediated gene4
intracellular migration4
conferred protection4
tandem mass4
cell leukemia4
vsb chain4
serum sample4
line expressing4
tier ii4
based expression4
igg responses4
replication step4
biological properties4
restore translation4
egfp complemented4
lethal homologous4
early shutoff4
induced caspase4
different attenuated4
cells compared4
markedly reduced4
hcl ph4
secreted ebovgp4
recurrent tumors4
dividing cells4
gene sequences4
cell markers4
type env4
times post4
minimal conserved4
latent state4
cells used4
nih aids4
induced release4
potent inhibition4
caudal thigh4
type gd4
dropwise added4
analysis using4
lytic infection4
synthesized proteins4
form hetero4
used previously4
lentiviral pseudotypes4
expression level4
efficient gene4
farther downstream4
sample buffer4
entry mediated4
highly immunogenic4
hypertonic conditions4
viral components4
neurotropic virus4
scanning model4
trypsin digestion4
promotes stable4
related viruses4
transfected hela4
three days4
budded virions4
protein incorporation4
nucleic acid4
described procedures4
growth curves4
chicken embryo4
protein levels4
gml oligomerization4
infected patients4
hpai viruses4
transgene delivery4
protected mice4
brain cancer4
class iii4
hal cleavage4
protein gene4
influenza strains4
emerging human4
ha hal4
determined whether4
intracellular membranes4
significant survival4
virus types4
target genes4
antigenic changes4
vectors containing4
borne viruses4
suboptimal context4
reduced polysome4
viral activity4
competent virus4
using baculovirus4
intraperitoneally treated4
affect viral4
cov receptor4
ic values4
high affinity4
treated group4
fatality rates4
culture dishes4
ebov vector4
mediated endocytosis4
endosomal proteolysis4
indicated time4
viruses possess4
gfp co4
vaccines expressing4
specific serum4
bearing hal4
fold greater4
invaded virus4
four groups4
connected er4
baculovirus particles4
chicken eggs4
robust increase4
significantly lower4
specific pathogen4
golgi localization4
stable cell4
adenovirus infection4
isg ifit4
remains unclear4
identified based4
viral vaccine4
mhc class4
coding sequences4
therapeutic approach4
envelope structure4
serial thin4
deletion mutants4
rlu well4
consecutive serial4
cas system4
antiviral responses4
much less4
intermediate compartment4
ml ml4
serine protease4
pseudovirus system4
induced fusion4
reverse primer4
cytoplasmic extracts4
calf serum4
case fatality4
suppressed doxorubicin4
therapeutic strategies4
subsequently incubated4
dense coat4
cottontail rabbit4
eukaryotic libraries4
ct region4
protective immunities4
mucosal immunization4
protein expressed4
host membrane4
slightly reduced4
leukemia viruses4
cycle growth4
becton dickinson4
hal activation4
inefficient gene4
transferred onto4
nonpermissive temperature4
bacterial infection4
eucaryotic ribosomes4
cell cytopathic4
abl kinase4
capsid display4
mek inhibitor4
virus containing4
bv ev4
proximal aug4
indicated otherwise4
mean age4
virus entirely4
viral attachment4
top panel4
activated protein4
transcriptional branch4
pseudotyped vector4
using mers4
preclinical studies4
polyclonal antibody4
phage display4
invasive tumor4
wt cells4
scale bars4
chorionic gonadotropin4
antibodies directed4
initiate translation4
favorable immune4
nl min4
retrograde transport4
human epithelial4
conventional mnt4
entry depends4
vlp release4
blocking buffer4
interferon induction4
microdose cytopathic4
replicative capacity4
two novel4
differential translation4
also indicated4
eukaryotic mrnas4
experimental animals4
cytoplasmic tails4
strongly induced4
healthy adults4
mouse antibody4
challenge studies4
culture collection4
cdna encoding4
bars denote4
antibody titres4
texas red4
major histocompatibility4
sha shazip4
marked reduction4
visualized using4
antiviral protection4
viral pathogens4
copii coats4
treatment groups4
viral transcription4
significantly suppressed4
dimensional structures4
packaging plasmid4
infectious vesicular4
enrichment analysis4
clearly demonstrated4
activity using4
viruses isolated4
experimentally infected4
vaccine expressing4
target sequence4
reporter virus4
nuclear export4
doxorubicin promotes4
human cases4
might also4
host gene4
virus cell4
enhance transduction4
pvsv xn4
persistently infected4
expressing human4
trypsin cleavage4
virus replicates4
overall translational4
attenuating mutations4
cdna clones4
er membranes4
complete inhibition4
gag proteins4
samples tested4
administered via4
pseudotype vectors4
confer protection4
barr virus4
proteins except4
will require4
cell activation4
preproinsulin mrna4
strongly suggests4
reference bud4
beckman sw4
direct interaction4
cell populations4
thermo scientific4
conserved transcription4
signal promotes4
expression led4
mm dtt4
glycoproteins gp4
antiviral mechanism4
negative plasma4
antibodies using4
vitro growth4
wt wt4
small size4
agarose beads4
primary screen4
glycoproteins appear4
virus isolation4
human chorionic4
hispidus cells4
schwannoma cell4
second protein4
animals died4
beetle virus4
protein subunit4
plant virus4
mrnas might4
mean fluorescence4
protein ct4
nearly identical4
promotes ripa4
parp levels4
danger signal4
susceptible cells4
ebola viruses4
control conditions4
virus dose4
plaque sizes4
days later4
na spike4
single vaccination4
fold serially4
lower panel4
simplex type4
cell epitopes4
moussa virus4
gml proteins4
primary cell4
envelope fusion4
ferret nv4
hemagglutinin polypeptide4
host defense4
inhibitory action4
internal membrane4
baculovirus transduction4
cellular debris4
results revealed4
carbohydrate components4
specific cellular4
gml oligomers4
heterologous viral4
pestis challenge4
expression cassette4
rna species4
stomatitis disease4
jersey serotype4
rna interference4
four hours4
poliovirusinfected cells4
see text4
methylene chloride4