Questions

This is a list of all the questions and their associated study carrel identifiers. One can learn a lot of the "aboutness" of a text simply by reading the questions.

identifier question
cord-262760-mf1pn587Could RNA- RNA recombination have played a role?
cord-252048-ftbjsoupCoronavirus avian infectious bronchitis virus Infectious bronchitis virus-evidence for recombination within the massachusetts serotype Infectious bronchitis Does IBV change slowly despite the capacity of the spike protein to vary greatly?
cord-257715-pbcr81qmThe seroepidemiology of genogroup 1 and genogroup 2 Norwalk- like viruses in Italy Breda virus- like particles in pigs in South Africa Inducible expression of the vaccinia virus A17L gene provides a synchronized system to monitor sorting of viral proteins during morphogenesis Porcine torovirus?
cord-290801-dv6aak01The 5 and 3 downstream AUG region elements are required for mosquito- borne flavivirus RNA replication RNA structures required for production of subgenomic flavivirus RNA La protein binds to NS5 and NS3 and to the 5 and 3 ends of Dengue 4 virus RNA Functional RNA elements in the dengue virus genome Autochthonous dengue fever in Croatia Impact of climate change and other factors on emerging arbovirus diseases Pathogenic flaviviruses Viral encephalomyelitis Origin and evolution of flavivirus 5 UTRs and panhandles: trans- terminal duplications?
cord-286658-9kco7qadWhy do RNA viruses recombine?
cord-287324-ecpicv5vHow severe and prevalent are Ebola and Marburg viruses?
cord-260422-z22t57jua cysteine- rich peptide mimics the normal metal- linked dimer interface Fuzzy complexes: a more stochastic view of protein function HIV-1 Tat, apoptosis and the mitochondria: a tubulin link?
cord-278939-z6kiee09Can Chinese medicine be used for prevention of corona virus disease 2019( COVID-19)?
cord-309205-l8vjtrjqThe prevalence of types I and II feline coronavirus infections in cats Protease- mediated entry via the endosome of human coronavirus 229E Deletions in the 7a ORF of feline coronavirus associated with an epidemic of feline infectious peritonitis Feline infectious peritonitis: still an enigma?
cord-288253-wqrhiq08what can they teach us about the severe acute respiratory syndrome?
cord-284479-75zgljetCan you teach old drugs new tricks?
cord-284479-75zgljetHow Far Are We?
cord-284479-75zgljetLuciferase- expressing Ebolaviruses as tools for screening of antivirals Emerging virus diseases: can we ever expect the unexpected?
cord-327682-i3uim0ziWhat's new with common colds?
cord-326320-flfrdrbiA potential antiviral drug for the treatment of SARS- CoV-2 by blocking the trimerization of viral spike glycoprotein?
cord-300883-rws11uelHowever, it is unclear whether the hMPV G- gene experienced differential selection pressures, or all the deduced amino acid sites evolved due to stochastic mutational processes?
cord-320331-wtxja5i9Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
cord-320331-wtxja5i9Can we contain the COVID-19 outbreak with the same measures as for SARS?
cord-295099-ghc85pf5Ammonium ions improve the survival of glutaminestarved hybridoma cells Isolation and characterization of anti ROR1 single chain fragment variable antibodies using phage display technique Development of a new yeast surface display system based on Spi1 as an anchor protein Passive immunization with the anti- HIV-1 human monoclonal antibody( hMAb) 4E10 and the hMAb combination 4E10/2F5/2G12 Global structure of HIV-1 neutralizing antibody IgG1 b12 is asymmetric Evaluation of a novel multi- immunogen vaccine strategy for targeting 4E10/10E8 neutralizing epitopes on HIV-1 gp41 membrane proximal external region Improved efficiency of EBV transformation of B- lymphocytes Single cell sorting and cloning Isolation of human monoclonal antibodies by mammalian cell display Antibody immunoprophylaxis and immunotherapy for influenza virus infection: utilization of monoclonal or polyclonal antibodies?
cord-290948-cuu78cvlThe non- structural protein nsp10 of mouse hepatitis virus binds zinc ions and nucleic acids Discovery of an RNA virus 3 → 5 exoribonuclease that is critically involved in coronavirus RNA synthesis Nidovirus transcription: how to make sense?
cord-279969-5nlmljcwThe 3?
cord-279969-5nlmljcwThis finding is comparable to the low conservation of some 3?
cord-284866-66azyje4An evaluation of measures of synonymous codon usage bias Genetic variability and molecular evolution of Hepatitis A virus MUSCLE: a multiple sequence alignment method with reduced time and space complexity Theory and Applications of Correspondence Analysis Initial sequencing and analysis of the human genome Analysis of synonymous codon usage in the UL24 gene of duck enteritis virus What drives codon choices in human genes?
cord-284866-66azyje4Why is CpG suppressed in the genomes of virtually all small eukaryotic viruses but not in those of large eukaryotic viruses?
cord-325973-e3rxr6oqRecent spreading of a divergent canine parvovirus type 2a( CPV-2a) strain in a CPV-2c homogenous population Host range relationships and the evolution of canine parvovirus Typing of canine parvovirus strains circulating in Brazil between Characterization of pantropic canine coronavirus from Brazil Development of a nested PCR assay for the detection of canine coronavirus Nucleotide sequence and genome organization of canine parvovirus Detection and genotyping of canine coronavirus RNA in diarrheic dogs in Japan Evolution of canine parvovirus − a need for new vaccines?
cord-325973-e3rxr6oqa possible new CPV-2a is emerging?
cord-276198-psjua913Does form meet function in the coronavirus replicative organelle?
cord-276198-psjua913Double- membrane organelles observed( x) or uncertainly observed(?) in infected cells are marked at right.
cord-276198-psjua913Secoviridae P ER V?
cord-290481-i2ppvsh5What could be the reason for multiplication of diverse suppressors in closteroviruses as opposed to single suppressors of smaller viruses?
cord-290481-i2ppvsh5What is the driving force behind the increase in viral genome complexity?
cord-290481-i2ppvsh5What is the functional significance of the increase in genome complexity seen in closteroviruses relative to the simpler plant viruses?
cord-290481-i2ppvsh5What would be considered an'environmental catastrophe'for a virus?
cord-290481-i2ppvsh5Why then the largest DNA viruses with the ∼1200 kb genomes are so much larger than the largest RNA viruses with the ∼30 kb genomes?
cord-290481-i2ppvsh5a titanic achievement?
cord-268337-o6lo55o8HIV mRNAs are capped, so why would a virus that expresses capped mRNAs encode a function that cleaves eIF4 G and represses cap- dependent translation and scanning?
cord-268337-o6lo55o8How would this be expected to affect translation?
cord-268337-o6lo55o8So how does proteinase cleavage of PABP affect translation?
cord-268337-o6lo55o8What could be the missing part(s) of the translation shutoff model?
cord-268337-o6lo55o8What effects do viral proteinases have on translation of viral mRNA?
cord-268337-o6lo55o8What else could have been missing from the shutoff model?
cord-268337-o6lo55o8While proteases of many picornaviruses and caliciviruses are known to cleave several translation factors, what of other RNA viruses?
cord-268337-o6lo55o8the function of PABP and PABP- interacting proteins in mRNA translation Mammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanisms Cleavage of poly(A)-binding protein by Coxsackievirus 2A protease in vitro and in vivo: another mechanism for host protein synthesis shutoff?
cord-285580-gq7400tq: What should a clinician really know?
cord-285580-gq7400tqCan nitric oxide overcome bacterial resistance to antibiotics?
cord-285580-gq7400tqCoagulation and inflammation cross- talking Could nasal nitric oxide help to mitigate the severity of COVID-19?
cord-285580-gq7400tqH1N1 Potential benefits of tryptophan metabolism to the efficacy of tocilizumab in COVID-19 Protocol for a randomized controlled trial testing inhaled nitric oxide therapy in spontaneously breathing patients with Nitric oxide- loaded chitosan nanoparticles as an innovative antileishmanial platform Pharmaceutical nanotechnology: which products are been designed against COVID-19?
cord-285580-gq7400tqInhalation of nitric oxide in the treatment of severe acute respiratory syndrome: A rescue trial in beijing To give or not to give?
cord-285580-gq7400tqInhaled nitric oxide treatment in spontaneously breathing COVID-19 patients Small molecules for great solutions: Can nitric oxide- releasing nanomaterials overcome drug resistance in chemotherapy?
cord-285580-gq7400tqNL63 molecular epidemiology and evolutionary patterns in rural coastal Kenya Serum levels of nitric oxide as a predictor of survival in acute respiratory distress syndrome caused by H1N1 pneumonia?
cord-344084-z4t2wkgk, the following question arose: does CCR5 have any clinically relevant influence on SARS- CoV-2 or other coronaviruses infections?
cord-344084-z4t2wkgk: forgotten or ignored?
cord-344084-z4t2wkgkAn emerging interplay between extracellular vesicles and cytokines Lack of chemokine receptor CCR5 promotes murine fulminant liver failure by preventing the apoptosis of activated CD1d- restricted NKT cells CCR5 in T cell- mediated liver diseases: what's going on?
cord-344084-z4t2wkgkCCR5 polymorphism as a protective factor for hepatocellular carcinoma in hepatitis B virus- infected Iranian patients CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface Effects of the CCR5-Δ32 mutation on antiviral treatment in chronic hepatitis C Effects of the CCR5-Δ32 mutation on hepatitis C virus- specific immune responses in patients with haemophilia CC- chemokine receptor 5( CCR5) in hepatitis C-- at the crossroads of the antiviral immune response?
cord-344084-z4t2wkgkCells Chemokine receptors as important regulators of pathogenesis during arboviral encephalitis Enhanced expression, native purification, and characterization of CCR5, a principal HIV-1 coreceptor Dengue haemorrhagic fever: a job done via exosomes?
cord-333180-xevie6tmAre all granzymes cytotoxic in vivo?
cord-333180-xevie6tmHow do viruses control mitochondria- mediated apoptosis?
cord-333180-xevie6tmThe emerging role of the interferon- induced PKR protein kinase as an apoptotic effector: a new face of death?
cord-333180-xevie6tmThe interferon response to intracellular DNA: why so many receptors?
cord-333180-xevie6tmThe question is what is the fate of the infected cells?
cord-333180-xevie6tmThe question is what is the fate of the infected cells?
cord-333180-xevie6tmvia which BH3-only protein?, see below)
cord-304424-048xo7jnA novel paramyxovirus?
cord-304424-048xo7jnAnd what exactly did the host look like then?
cord-304424-048xo7jnAre we missing half of the viruses in the ocean?
cord-304424-048xo7jnAt what point in host evolution does an RNA viral pathogen arrive?
cord-304424-048xo7jnCRISPR- Cas9 Species- level deconvolution of metagenome assemblies with Hi- C- based contact probability maps Virus discovery: are we scientists or genome collectors?
cord-304424-048xo7jnMetagenomics for the discovery of novel human viruses Global epidemiology of noninfluenza RNA respiratory viruses: data gaps and a growing need for surveillance Viral metagenomics on animals as a tool for the detection of zoonoses prior to human infection?
cord-304424-048xo7jnOther than sampling more broadly and maintaining the exponential growth in Genbank, what are orthogonal challenges for future RNA virus metagenomic studies?
cord-304424-048xo7jnTombusviridae and Nodaviridae?
cord-304424-048xo7jnWhat do you get when you cross a picornavirus and a calicivirus?
cord-304424-048xo7jnWhere do we begin with RNA virus metagenomics?
cord-304424-048xo7jnWhy has RNA virus metagenomics been so successful?