bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
asthma exacerbations	644
lung function	567
allergic rhinitis	483
respiratory tract	404
severe asthma	376
epithelial cells	359
specific ige	339
asthma control	336
airway inflammation	327
asthma exacerbation	302
viral infections	287
respiratory syncytial	264
syncytial virus	259
childhood asthma	238
asthma symptoms	236
viral infection	228
food allergy	220
lung cancer	214
respiratory viruses	210
lung disease	204
acute asthma	204
immune response	203
pulmonary disease	201
atopic dermatitis	198
air pollution	197
risk factors	195
asthmatic patients	190
lower respiratory	185
chronic obstructive	181
control group	181
skin prick	178
obstructive pulmonary	173
increased risk	172
asthma patients	172
induced asthma	167
respiratory infections	167
smooth muscle	160
dust mite	156
united states	156
allergic asthma	155
mean age	152
pulmonary function	150
respiratory symptoms	150
allergic diseases	148
risk factor	148
house dust	147
asthmatic children	145
airway epithelial	144
systematic review	144
inhaled corticosteroids	143
nitric oxide	143
controlled trial	140
peripheral blood	140
cohort study	138
asthma severity	137
respiratory disease	137
young children	135
ige levels	133
mast cells	131
early life	129
allergic disease	127
years old	127
airway obstruction	126
upper respiratory	125
total ige	125
grass pollen	124
persistent asthma	123
age years	122
respiratory viral	122
acute respiratory	122
bone marrow	121
tract infections	121
cystic fibrosis	119
bronchial asthma	116
significantly higher	116
case report	115
may also	115
immune system	110
bronchial epithelial	109
virus infection	107
dendritic cells	106
nasal polyps	106
statistically significant	105
allergic patients	104
prick test	103
growth factor	103
health care	103
asthmatic subjects	102
tract infection	101
exhaled nitric	101
cd cd	100
airway hyperresponsiveness	99
air quality	99
early childhood	96
family history	96
viral respiratory	96
immune responses	96
rhinovirus infection	95
airway epithelium	93
side effects	93
pregnant women	93
airflow obstruction	91
adverse events	90
significant difference	89
common cold	89
prick tests	88
da asma	88
first year	86
mast cell	86
current asthma	86
emergency department	85
year old	84
peak flow	84
clinical trials	83
pulmonary fibrosis	82
otitis media	81
mg ml	81
clinical trial	81
airway disease	80
data suggest	80
chronic respiratory	80
allergic sensitization	80
skin tests	80
human metapneumovirus	80
airway smooth	79
skin test	79
clinical practice	79
airway remodeling	79
und die	79
respiratory virus	78
randomized controlled	78
prospective study	78
influenza virus	77
children aged	77
gene expression	77
primary care	76
doc id	76
respiratory health	76
preschool children	76
inflammatory response	76
cord uid	76
recurrent wheezing	75
respiratory diseases	75
high risk	75
expiratory flow	75
respiratory infection	74
environmental factors	74
flow cytometry	74
serum ige	73
eosinophilic inflammation	73
asthma attacks	73
important role	72
inflammatory cytokines	72
bronchoalveolar lavage	71
birth cohort	71
asthma development	71
least one	71
innate immune	70
allergic reactions	70
acute exacerbations	70
chronic asthma	69
ng ml	69
human rhinovirus	69
high levels	69
pg ml	68
allergic inflammation	68
healthy controls	68
asm cells	68
diagnosed asthma	67
epithelial cell	67
control subjects	67
significant differences	67
nasal spray	66
rv infection	66
respiratory illness	66
lung diseases	66
asthma management	65
mrna expression	65
among children	65
mg dl	65
disease severity	64
recent studies	64
lung tissue	64
cigarette smoke	64
inflammatory cells	64
one study	64
natural history	64
recent study	64
dust mites	63
peak expiratory	63
copd patients	63
allergen exposure	63
lower airway	62
mg kg	62
respiratory system	62
skin testing	62
two groups	62
induced sputum	62
rsv infection	61
well tolerated	61
significantly increased	61
tobacco smoke	61
old children	60
iu ml	60
mouse model	60
fev fvc	60
older adults	60
severe ea	60
adverse effects	60
first years	60
bronchial hyperresponsiveness	60
hygiene hypothesis	60
forced expiratory	60
interstitial lung	59
oxidative stress	59
without asthma	58
asthma prevalence	58
eosinophil counts	58
informed consent	58
uncontrolled asthma	58
medication use	58
food allergens	57
inhaled corticosteroid	57
cytokine production	57
may contribute	57
infl uenza	57
clinical symptoms	57
age group	57
allergic airway	56
elderly patients	56
asthma bronchiale	56
general population	55
monoclonal antibody	55
positive skin	55
respiratory distress	55
asthma medication	54
one year	54
th cells	54
eosinophilic esophagitis	54
allergen challenge	54
seasonal allergic	54
commonly used	53
bei der	53
function testing	53
upper airway	53
adult patients	53
measured using	53
indoor air	53
asthma phenotypes	53
auf die	53
also found	52
controlled trials	52
serum levels	52
feno levels	51
airway responsiveness	51
mechanical ventilation	51
logistic regression	51
eosinophil count	51
public health	51
hospital admissions	51
old male	51
significant increase	50
another study	50
controlled asthma	50
higher risk	50
atopic asthma	50
one patient	49
chronic rhinosinusitis	49
type i	49
nasal congestion	49
respiratory pathogens	49
lower airways	49
chronic inflammatory	48
asthma treatment	48
obstructive sleep	48
acute exacerbation	48
patients treated	48
airway resistance	48
respiratory illnesses	48
mg day	48
thoracic society	48
specific immunotherapy	47
specific igg	47
per year	47
significantly reduced	47
symptom score	47
control study	46
general practice	46
food allergies	46
weight loss	46
performed using	46
chest tightness	46
increased airway	46
chronic lung	46
long term	46
idiopathic pulmonary	46
human bocavirus	46
study showed	46
nasal polyposis	46
function tests	45
hypersensitivity reactions	45
chronic urticaria	45
pilot study	45
peanut allergy	45
like receptor	45
asthma outcomes	45
study group	45
pediatric asthma	45
pollen season	45
significantly associated	44
sleep apnea	44
median age	44
innate immunity	44
systemic corticosteroids	44
fatty acids	44
tidal breathing	44
air pollutants	44
asthma diagnosis	44
significant improvement	44
several studies	44
clinical characteristics	43
abdominal pain	43
stable asthma	43
rsv bronchiolitis	43
blood eosinophil	43
year follow	43
induced wheezing	43
allergic symptoms	43
im rahmen	42
onset asthma	42
poor asthma	42
mild asthma	42
adhesion molecule	42
acting beta	42
ige level	41
aber auch	41
adrenergic receptor	41
united kingdom	41
thymic stromal	41
may lead	41
chlamydia pneumoniae	41
ocs dose	41
birth weight	41
stromal lymphopoietin	41
nasal symptoms	41
hay fever	41
leukotriene receptor	40
significantly lower	40
neutrophilic inflammation	40
basic protein	40
auch die	40
immune cells	40
controlled study	40
severe disease	40
may result	40
equine asthma	40
th response	39
asthma may	39
animal models	39
milk allergy	39
respiratory failure	39
pulmonary hypertension	39
eosinophilic asthma	39
asthma education	39
clinical presentation	39
results suggest	39
mycoplasma pneumoniae	39
two years	39
developing asthma	39
provocation test	39
physical examination	39
allergic reaction	39
respiratory function	39
world health	39
oral corticosteroids	39
cell lines	39
expiratory volume	39
induced airway	39
asthma pathogenesis	39
influenza vaccination	38
airway hyper	38
atopic disease	38
clinical features	38
airflow limitation	38
sectional study	38
old female	38
extracellular matrix	38
disordered breathing	37
wheezing episodes	37
nasal mucosa	37
adult asthma	37
necrosis factor	37
including asthma	37
patients received	37
hong kong	37
major basic	37
pediatric patients	37
severe exacerbations	37
intensive care	37
old woman	37
allergic rhinoconjunctivitis	37
th cytokines	37
osa patients	37
airway remodelling	37
odds ratio	37
placebo group	37
inflammatory mediators	37
growth factors	37
ventilation heterogeneity	37
hypereosinophilic syndrome	36
pinto mendes	36
disease control	36
polymerase chain	36
previous studies	36
guinea pigs	36
chain reaction	36
antibiotic use	36
airway diseases	36
mononuclear cells	36
severe persistent	36
budesonide formoterol	36
allergic subjects	36
treatment group	36
may occur	36
significant reduction	36
aged years	36
experimental rhinovirus	36
may play	36
fev predicted	36
chronic disease	36
building syndrome	36
national health	36
healthy individuals	36
studies suggest	35
sbs symptoms	35
inhaled steroids	35
many patients	35
distress syndrome	35
particulate matter	35
birch pollen	35
human eosinophils	35
positive correlation	35
sick building	35
medical history	35
age groups	35
symptom scores	35
acute wheezing	35
hospital admission	35
children hospitalized	35
amino acid	34
chronic inflammation	34
bacterial infections	34
transforming growth	34
virus bronchiolitis	34
moderate asthma	34
copd subjects	34
oral steroids	34
inflammatory diseases	34
sublingual immunotherapy	34
clinical outcomes	34
action plan	34
increased levels	34
ige binding	34
higher levels	34
receptor antagonists	34
randomised controlled	34
outdoor air	34
infectious diseases	34
acute bronchitis	33
global initiative	33
recent years	33
allergen immunotherapy	33
occupational asthma	33
protein levels	33
observational study	33
bronchopulmonary dysplasia	33
test results	33
longitudinal study	33
factors associated	33
primary outcome	33
may help	33
ige antibodies	33
eosinophilic infiltration	33
retrospective study	33
regression analysis	33
fi rst	33
blood eosinophilia	33
allergic response	32
human airway	32
twice daily	32
among patients	32
fluticasone propionate	32
high prevalence	32
egg white	32
lung volumes	32
determine whether	32
two patients	32
inclusion criteria	32
receptor antagonist	32
mild persistent	32
clinically relevant	32
epidemiological studies	32
smoke exposure	32
blood eosinophils	32
health effects	32
asthma medications	32
findings suggest	32
chronic cough	32
eosinophil infiltration	32
like symptoms	32
muc ac	32
cd cells	32
exhaled breath	32
severe allergic	32
literature review	32
bronchial epithelium	32
drug allergy	32
healthy children	31
common cause	31
heart rate	31
collagen iv	31
asthmatic individuals	31
proinflammatory cytokines	31
health organization	31
cationic protein	31
th cytokine	31
und der	31
asthma risk	31
fatty acid	31
sputum eosinophils	31
airway eosinophilia	31
endotoxin levels	31
young adults	31
blood mononuclear	31
vital capacity	31
cohort studies	31
lung volume	31
school children	31
cancer cells	31
phase ii	31
mass spectrometry	31
combination therapy	31
bronchial hyperreactivity	31
refractory asthma	30
nasal polyp	30
hearing loss	30
candidate genes	30
igg levels	30
also known	30
asthma therapy	30
cell responses	30
normal subjects	30
airway hyperreactivity	30
mass index	30
protective effect	30
clinical course	30
body mass	30
health outcomes	30
see table	30
gastroesophageal reflux	30
fold increase	30
randomized trial	30
respiratory rate	30
corticosteroid treatment	30
environmental exposures	30
eosinophil cationic	30
ics laba	30
airway wall	30
eosinophil recruitment	30
total protein	29
mite allergen	29
rhinovirus infections	29
clinical manifestations	29
treatment groups	29
risk children	29
forced oscillation	29
healthy subjects	29
inflammatory cell	29
differential diagnosis	29
nitrogen dioxide	29
study aimed	29
basement membrane	29
poorly controlled	29
clinical efficacy	29
ist die	29
phase iii	29
patients may	29
tumor necrosis	29
safety profile	29
ct scan	29
pollen allergy	29
barrier function	29
chart review	29
consecutive patients	29
asthma morbidity	29
skeletal muscle	29
prospective cohort	29
low birth	29
significantly decreased	29
allergen sensitization	28
asm cell	28
th th	28
endotoxin exposure	28
bal fluid	28
aspergillus fumigatus	28
asthma action	28
last months	28
cell counts	28
patients without	28
significantly greater	28
goblet cell	28
primary prevention	28
cell activation	28
requiring hospitalization	28
care unit	28
lavage fluid	28
asthmatic airways	28
phagocytic ability	28
oscillation technique	28
eosinophilic myositis	28
genome load	28
clinical studies	28
present study	28
influenza vaccine	28
sputum samples	27
high doses	27
inhaled steroid	27
chronic airway	27
clinically significant	27
rhinovirus genome	27
nocturnal enuresis	27
also associated	27
study found	27
helper type	27
als auch	27
inflammatory responses	27
mit der	27
allergischer erkrankungen	27
viral replication	27
even though	27
family members	27
nasal aspirates	27
tree nut	27
structural changes	27
virus infections	27
celiac disease	27
adverse reactions	27
asthma group	27
reflux disease	27
mit einer	27
inflammatory airway	27
chronic bronchitis	27
cells mm	27
last years	27
hrv infection	27
breath condensate	27
last year	27
sensitive asthma	27
american thoracic	27
alveolar macrophages	27
epithelial barrier	27
diagnostic criteria	27
widely used	27
airway function	27
cysteinyl leukotrienes	26
heart disease	26
per person	26
within minutes	26
previously reported	26
leading cause	26
two different	26
atopic diseases	26
office buildings	26
bacterial infection	26
increased prevalence	26
cell count	26
tidal volume	26
reported asthma	26
cat allergen	26
wheezing illness	26
sample size	26
cancer cell	26
much higher	26
significantly improved	26
blood pressure	26
cord blood	26
previous months	26
reduced lung	26
blood flow	26
eosinophils may	26
cell differentiation	26
low dose	26
innate lymphoid	26
first time	26
clinical history	26
recurrent airway	26
cell line	26
effective treatment	26
connective tissue	26
clinical improvement	26
asthma care	26
patients aged	26
per week	26
environmental tobacco	26
taken together	26
systemic inflammation	26
better understanding	26
clinical assessment	26
control groups	26
potential role	26
acquired pneumonia	25
intervention group	25
based study	25
statistical analysis	25
cells may	25
also showed	25
granule proteins	25
pulmonary artery	25
within hours	25
studies showed	25
patch test	25
ex vivo	25
heart failure	25
gold standard	25
ipratropium bromide	25
wheezing episode	25
major allergen	25
elevated levels	25
wide range	25
allergen avoidance	25
preterm infants	25
treatment period	25
community study	25
significant correlation	25
significant decrease	25
serum periostin	25
severe respiratory	25
sputum eosinophilia	25
international study	25
lung transplantation	25
allergic conjunctivitis	25
zu einer	25
asthma among	25
may cause	25
challenge test	25
clinical relevance	25
many studies	25
blood samples	25
immune function	25
severe acute	25
emergency room	25
airway pressure	25
health study	25
epidemiologic studies	25
hypertonic saline	25
ige mediated	24
rhinovirus illnesses	24
airways disease	24
contact dermatitis	24
clinically diagnosed	24
gastrointestinal tract	24
bronchodilator response	24
high dose	24
significantly different	24
fvc ratio	24
mc sn	24
urgent hcu	24
may reduce	24
da resposta	24
study population	24
bronchial mucosa	24
fungal sensitization	24
moderate ea	24
allergic bronchopulmonary	24
subsequent development	24
azelastine nasal	24
serum total	24
prospective studies	24
natural killer	24
asthma candidate	24
atopic eczema	24
past months	24
tree pollen	24
cell types	24
first months	24
microbial products	24
blood cells	24
national asthma	24
six months	24
indoor environment	24
asthma phenotype	24
evidence suggests	24
obstructive lung	24
parainfluenza virus	24
university hospital	24
asthma guidelines	24
control medication	24
multiplex pcr	24
strongly associated	24
higher prevalence	24
port hedland	24
hospitalized children	24
one week	24
time pcr	24
des arg	24
control test	24
rhinitis symptoms	24
food challenge	23
anaphylactic reaction	23
dermatophagoides pteronyssinus	23
ige reactivity	23
year history	23
determined using	23
atopic status	23
tract symptoms	23
control measures	23
large number	23
older people	23
clinical diagnosis	23
systemic steroids	23
histamine release	23
lung inflammation	23
sputum eosinophil	23
preterm birth	23
treated patients	23
asthma hospitalizations	23
clinical response	23
candidate gene	23
volatile organic	23
hypersensitivity reaction	23
maintenance dose	23
lower levels	23
detection rate	23
inhalant allergens	23
cell proliferation	23
viral bronchiolitis	23
recurrent infections	23
acute viral	23
cell apoptosis	23
patients receiving	23
allergic children	23
tissue eosinophilia	23
less likely	23
adaptive immune	23
hemmung der	23
chronic sinusitis	23
age range	23
sleep disordered	23
gold stage	23
smoking history	23
fractional exhaled	23
durch die	23
lymph nodes	23
th responses	23
key role	23
severe rsv	23
childhood wheezing	23
small number	23
atopic patients	23
nasal lavage	23
elderly asthmatic	23
oral corticosteroid	23
included patients	22
host disease	22
older children	22
positive control	22
task force	22
asthma asthma	22
pediatric population	22
reactive protein	22
prick testing	22
health survey	22
well known	22
like receptors	22
eosinophil activation	22
cysteinyl leukotriene	22
written informed	22
human coronavirus	22
endothelial cells	22
significantly less	22
monoclonal antibodies	22
patients undergoing	22
increased susceptibility	22
corticosteroid therapy	22
influenza viruses	22
increased expression	22
allergy clinic	22
confidence interval	22
immune deficiency	22
body weight	22
eosinophil numbers	22
year period	22
late asthmatic	22
mg bid	22
chronic diseases	22
dependent asthma	22
patients using	22
staphylococcus aureus	22
million people	22
reactive oxygen	22
lung microbiome	22
major cause	22
atypical bacteria	22
smoking cessation	22
patient presented	22
children younger	22
oral challenge	21
lymphoid cells	21
skin biopsy	21
forced vital	21
human lung	21
national heart	21
infected cells	21
atopic children	21
latex allergy	21
relatively low	21
currently available	21
total serum	21
aged children	21
specific antibody	21
diagnostic tests	21
genetic factors	21
peripheral eosinophilia	21
streptococcus pneumoniae	21
blood institute	21
fi ndings	21
low levels	21
bronchial reactivity	21
nasal secretions	21
intermittent asthma	21
medical center	21
may increase	21
per day	21
healthy volunteers	21
nasal obstruction	21
productive cough	21
intercellular adhesion	21
results showed	21
study using	21
beneficial effect	21
allograft rejection	21
three months	21
clinical data	21
clinical signs	21
ige sensitization	21
cell surface	21
viral detection	21
lung biopsy	21
muscarinic receptors	21
results patients	21
mucociliary clearance	21
aufgrund der	21
commercially available	21
asthma attack	21
challenge tests	21
genetic variants	21
minute ventilation	21
recurrent respiratory	21
asthmatic response	21
tissue damage	21
cell function	21
von pge	21
oral antibiotics	21
allergic disorders	21
hospitalized patients	21
exclusion criteria	21
asthma triggers	21
small airways	20
study also	20
high resolution	20
extracellular traps	20
otherwise healthy	20
may affect	20
similar results	20
average age	20
statistical analyses	20
patients underwent	20
positive response	20
diffusing capacity	20
metapneumovirus infection	20
statistical significance	20
airway narrowing	20
also play	20
cigarette smoking	20
data collection	20
prevalence rates	20
methods data	20
pulmonary vascular	20
computed tomography	20
parainfluenza viruses	20
von il	20
greater risk	20
study period	20
may reflect	20
protein kinase	20
asthma subjects	20
case reports	20
will also	20
global strategy	20
infectious agents	20
lung injury	20
asthma using	20
signifi cantly	20
related quality	20
associated asthma	20
subcutaneous immunotherapy	20
preliminary data	20
study will	20
symptom control	20
blind placebo	20
life questionnaire	20
type ii	20
response rate	20
significant association	20
pollen counts	20
mit einem	20
high fat	20
infl ammation	20
skin lesions	20
patient outcomes	20
molecular mechanisms	20
neutrophilic asthma	20
age children	20
aumento da	20
airway eosinophils	20
function impairment	20
bronchopulmonary aspergillosis	20
study design	20
flow rate	20
poor control	20
may provide	20
positive airway	20
emphysema severity	20
mouse models	20
oxygen species	20
der allergischen	20
allergy testing	20
months prior	20
school age	20
trigger asthma	20
type iii	19
airway lumen	19
drug allergies	19
pleural effusions	19
ventilation rate	19
eosinophilic gastroenteritis	19
human bronchial	19
differentially expressed	19
chest pain	19
data indicate	19
gina guidelines	19
dose response	19
two weeks	19
oral food	19
positive results	19
dass die	19
dose ics	19
muscle mass	19
host cell	19
wide association	19
induced exacerbations	19
patch tests	19
children without	19
reference equations	19
british thoracic	19
old boy	19
anaphylactic reactions	19
maternal smoking	19
antibiotic therapy	19
studies using	19
arterial blood	19
cat dander	19
der atemwege	19
treat asthma	19
healthy control	19
coronavirus disease	19
receptor expression	19
pulmonary arterial	19
less common	19
dose inhaler	19
control questionnaire	19
normal range	19
current study	19
environmental control	19
neutrophilic airway	19
cell death	19
reference values	19
significant role	19
amino acids	19
month follow	19
intranasal steroids	19
predictive value	19
carbon monoxide	19
control cells	19
physical exam	19
fungal spores	19
medical care	19
randomized clinical	19
city children	19
three years	19
milk protein	19
treatment options	19
higher incidence	19
acute bronchiolitis	19
years ago	19
odds ratios	19
organic compounds	19
well established	19
allergy symptoms	19
significant reductions	19
oral prednisolone	19
acupuncture treatment	19
allergy clin	19
closely related	19
rhinitis patients	19
health status	18
two studies	18
developed countries	18
serum tryptase	18
mild ea	18
younger age	18
nos primeiros	18
autoimmune disease	18
nasal blockage	18
th cell	18
higher doses	18
macrolide antibiotics	18
asthma respiratory	18
clinical study	18
important risk	18
haemophilus influenzae	18
vor allem	18
cpap therapy	18
asthma associated	18
first case	18
carbon dioxide	18
cytokines il	18
common respiratory	18
retrospective chart	18
patients showed	18
ed visits	18
murine model	18
future studies	18
lung cancers	18
environmental exposure	18
guinea pig	18
significantly elevated	18
signifi cant	18
middle ear	18
die bildung	18
atopic sensitization	18
study conducted	18
double blind	18
patients suffering	18
chest ct	18
acute attacks	18
also demonstrated	18
nut allergy	18
cardiovascular disease	18
sputum induction	18
stimulating factor	18
elevated serum	18
third trimester	18
often used	18
respiratory events	18
serum specific	18
new york	18
within weeks	18
transcription factor	18
th immune	18
ciliary dyskinesia	18
nasal epithelial	18
total lung	18
asthma quality	18
cell hyperplasia	18
specific antibodies	18
quantitative pcr	18
group compared	18
independent risk	18
individual patient	18
clinical setting	18
pcr assays	18
clinical problems	18
free diet	18
patienten mit	18
atopic asthmatic	18
least months	18
analysis revealed	18
wheezing children	18
may influence	18
inflammatory process	18
eosinophil degranulation	18
gut microbiome	18
adhesion molecules	18
systematic reviews	18
improved asthma	18
da atopia	18
pneumoniae infection	18
asthmatic adults	18
virus detection	18
international recommendations	18
four patients	17
cell volume	17
primary ciliary	17
antibiotic exposure	17
short course	17
nk cells	17
white blood	17
transcription factors	17
asthma compared	17
machine learning	17
oesophageal reflux	17
ige receptor	17
body size	17
significant change	17
increased asthma	17
general practitioners	17
isaac phase	17
within normal	17
department visits	17
respiratory conditions	17
naturally occurring	17
inhalant allergies	17
one third	17
bei kindern	17
upper airways	17
nervous system	17
arterial hypertension	17
nucleic acids	17
bildung von	17
single dose	17
may represent	17
month period	17
tidal volumes	17
study included	17
breast feeding	17
allergy asthma	17
und eine	17
virus replication	17
often associated	17
mean fev	17
deficient mice	17
consensus statement	17
predicted fev	17
school performance	17
predict asthma	17
studies indicate	17
cc genotype	17
first strategy	17
incidence rates	17
observational studies	17
idiopathic eosinophilic	17
genes associated	17
bronchial responsiveness	17
persistent airway	17
pulmonary inflammation	17
five patients	17
clin immunol	17
topical steroids	17
common chronic	17
ethnic differences	17
adverse reaction	17
pulmonary embolism	17
inflammatory cytokine	17
related asthma	17
remains unclear	17
im vergleich	17
two children	17
percentage change	17
progenitor cells	17
every day	17
systemic reactions	17
health problem	17
desensitization protocol	17
gestational age	17
maintenance therapy	17
normal lung	17
basophil activation	17
may modulate	17
sensitized mice	17
oxygen saturation	17
reverse transcription	17
also reported	17
symptom severity	17
high level	17
rheumatoid arthritis	17
hyperactivity disorder	17
cellular senescence	17
eosinophil granule	17
multivariate analysis	17
gas exchange	17
cd high	17
generalized urticaria	17
common causes	17
methods children	17
histamine challenge	17
building materials	17
disease burden	17
autoimmune diseases	17
severe atopic	17
case series	17
chemokine production	17
wide variety	16
ventilation rates	16
allergic contact	16
ets formation	16
total number	16
medical thoracoscopy	16
lg ml	16
positive biopsy	16
clinical immunology	16
antitrypsin deficiency	16
mdi spacer	16
related symptoms	16
sowie die	16
secretory iga	16
early detection	16
also observed	16
following treatment	16
respiratory mechanics	16
oral immunotherapy	16
aktivierung von	16
rahmen der	16
und il	16
enclosure volume	16
first episode	16
new zealand	16
viral load	16
analyzed using	16
national institute	16
unknown whether	16
novel coronavirus	16
epithelial damage	16
usual care	16
action plans	16
disease states	16
airway neutrophils	16
office workers	16
induced allergic	16
tumor cells	16
patients sensitized	16
patient developed	16
sputum cell	16
dynamic hyperinflation	16
outcome measures	16
association studies	16
group showed	16
acid reflux	16
negative skin	16
eosinophilic colitis	16
old man	16
persistent symptoms	16
difficult asthma	16
reproductive factors	16
chronic otitis	16
interstitial pneumonia	16
western blot	16
beneficial effects	16
least two	16
muscle cells	16
longitudinal cohort	16
patients admitted	16
residual capacity	16
inflammatory disease	16
neutrophil extracellular	16
chronic rhinitis	16
bronchodilator reversibility	16
asthma susceptibility	16
gp dstat	16
ige antibody	16
pollen allergic	16
fat meal	16
treg cells	16
analysis showed	16
infl ammatory	16
outpatient visits	16
bosentan therapy	16
asthma foundation	16
possible role	16
poorly understood	16
inhaled allergens	16
respiratory comorbidity	16
wt mice	16
alternative medicine	16
alternative splicing	16
children ages	16
deficit hyperactivity	16
asthmatic airway	16
three patients	16
rna viruses	16
infection may	16
three groups	16
early morning	16
lung infection	16
cow milk	16
increased il	16
effector cells	16
provocation tests	16
early diagnosis	16
remains controversial	16
hypersensitivity pneumonitis	16
human asthma	16
os estudos	16
mandibular enclosure	16
rescue medication	16
resposta imune	16
reversible airway	16
inverse correlation	16
functional residual	16
different types	16
pulmonary blood	16
severe symptoms	16
challenged mice	16
egg allergy	16
single infections	16
term outcomes	16
study demonstrated	16
respiratory syndrome	16
aqol scores	16
isaac questionnaire	16
vitro studies	16
persistent wheezing	16
pollen exposure	16
mature dcs	16
adaptive immunity	16
european countries	16
patients hospitalized	16
induced anaphylaxis	16
patients referred	16
longitudinal studies	16
three different	16
national institutes	16
vlcd program	16
critical role	16
medical research	16
higher among	16
bacterial pathogens	15
care utilization	15
function test	15
days later	15
nutrition examination	15
perinatal outcomes	15
rhinovirus colds	15
child health	15
also increased	15
healthy infants	15
written asthma	15
later childhood	15
airway reactivity	15
alternaria alternata	15
ocular symptoms	15
perennial allergic	15
copd exacerbations	15
steroid treatment	15
older asthmatic	15
mite allergens	15
cold air	15
study shows	15
first two	15
several different	15
asthma research	15
goblet cells	15
single nucleotide	15
cytokine profiles	15
mucus production	15
asthma will	15
older patients	15
factor receptor	15
significant changes	15
continuous positive	15
daily activities	15
dendritic cell	15
antibiotic treatment	15
less severe	15
newly discovered	15
western blotting	15
cat exposure	15
allergy syndrome	15
systemic symptoms	15
healthy smokers	15
lung health	15
clinical severity	15
chlamydophila pneumoniae	15
bronchial brushing	15
epidermal growth	15
fungal allergens	15
six years	15
serum il	15
chronic infection	15
des asthma	15
human disease	15
may induce	15
indoor environments	15
data will	15
sich die	15
asthma incidence	15
asthma related	15
univariate analysis	15
infection control	15
total score	15
immunosorbent assay	15
ecp levels	15
diseases including	15
recurrent wheeze	15
runny nose	15
healthy adults	15
ats ers	15
inflammatory markers	15
developing countries	15
protein expression	15
oral allergy	15
treatment strategies	15
nasal symptom	15
respiratory epithelial	15
standard treatment	15
stranded rna	15
bacterial species	15
whole blood	15
lung transplant	15
cell adhesion	15
positive spt	15
vital signs	15
beclomethasone dipropionate	15
decreased lung	15
evaluation revealed	15
past medical	15
per month	15
wheezing rhinovirus	15
preterm delivery	15
roc curve	15
complete resolution	15
hospital stay	15
common colds	15
icu admission	15
patients completed	15
gastrointestinal symptoms	15
gabe von	15
food sensitization	15
positive test	15
inflammatory effects	15
igg antibodies	15
lung capacity	15
asthma mortality	15
disease progression	15
multiple logistic	15
every weeks	15
authors declare	15
antibody responses	15
mechanisms underlying	15
auch bei	15
patients presented	15
associated wheezing	15
therapy may	15
clinical research	15
receptor gene	14
und den	14
potential risk	14
ist es	14
log feno	14
der lunge	14
examination survey	14
may include	14
methods patients	14
per patient	14
lung development	14
serum samples	14
stage iii	14
premature infants	14
among adults	14
primary endpoint	14
scfos lcfos	14
blood cultures	14
asthma immunology	14
human rhinoviruses	14
detection rates	14
lower limit	14
patient education	14
liver disease	14
activated eosinophils	14
incidence rate	14
macrophage colony	14
asthma cases	14
allergen components	14
lymph node	14
von der	14
barrier integrity	14
respiratory epithelium	14
auch eine	14
effector functions	14
calculated using	14
small airway	14
african american	14
polyp tissue	14
also shown	14
serum concentrations	14
blood tests	14
incident asthma	14
bronchial obstruction	14
better understand	14
mexico city	14
cam therapies	14
von eosinophilen	14
medical records	14
mg qd	14
disease characterized	14
asthma prevention	14
two months	14
early exposure	14
patient reported	14
mean score	14
animal model	14
likely due	14
increased numbers	14
respiratory inflammation	14
supplemental oxygen	14
mg daily	14
using multiple	14
breast milk	14
allergic inflammatory	14
viral rna	14
low risk	14
health services	14
pollen allergens	14
reversibility testing	14
age asthma	14
may improve	14
eosinophil levels	14
current smokers	14
case illustrates	14
term follow	14
laboratory tests	14
expression levels	14
gi tract	14
protective effects	14
outpatient clinic	14
placental abruption	14
children whose	14
patients will	14
inflammatory bowel	14
five years	14
high concentrations	14
mechanisms involved	14
drug reaction	14
using spss	14
life exposure	14
clinical outcome	14
milk proteins	14
atopic subjects	14
one second	14
hmpv infection	14
patients whose	14
passive smoking	14
treated mice	14
asthmatic patient	14
higher rate	14
may indicate	14
well controlled	14
serum immunoglobulin	14
human subjects	14
asthma assessment	14
will help	14
polyunsaturated fatty	14
rsv infections	14
cancer patients	14
fish oil	14
variable airflow	14
cluster analysis	14
three times	14
epidemiological study	14
ragweed pollen	14
three days	14
specific immunoglobulin	14
comorbid conditions	14
steroid therapy	14
receptor agonists	14
vascular endothelial	14
much lower	14
bronchial challenge	14
drug reactions	14
animal studies	14
international guidelines	14
two thirds	14
cytokine il	14
aus der	14
identifi ed	14
au ml	14
children may	14
panel report	14
one hundred	14
life predict	14
clinical benefit	14
studies show	14
beim asthma	14
common allergens	14
high rhinovirus	14
practice guidelines	14
maintenance treatment	14
association study	14
je nach	14
motif chemokine	14
affected horses	14
may benefit	14
oral mucosa	14
children less	14
endothelial growth	13
ige synthesis	13
major allergens	13
nasal swab	13
recurrent episodes	13
nasal discharge	13
poor metabolizers	13
several factors	13
higher frequency	13
hdm slit	13
maintenance phase	13
blood count	13
cell lung	13
written action	13
gas transfer	13
placebo controlled	13
weeks gestation	13
ist ein	13
infections may	13
lung damage	13
ct scans	13
pleural effusion	13
bronchial hyper	13
induced lung	13
genetic studies	13
past years	13
positive controls	13
less clear	13
many cases	13
among people	13
control asthma	13
assessed using	13
routine clinical	13
line treatment	13
severe bronchiolitis	13
human influenza	13
underlying mechanisms	13
respiratory study	13
intervention strategy	13
mesothelin levels	13
regression model	13
reduces asthma	13
secondary prevention	13
fi brosis	13
crs patients	13
von mutius	13
related air	13
respiratory medicine	13
type response	13
elderly asthmatics	13
line therapy	13
reduce asthma	13
eosinophilic airway	13
also identified	13
skin diseases	13
winter months	13
parental history	13
central role	13
glutathione peroxidase	13
independent predictors	13
day care	13
serum level	13
die allergische	13
comparative study	13
hiv infection	13
also significantly	13
acute episode	13
negative control	13
dry cough	13
symptoms related	13
time period	13
four weeks	13
may explain	13
respiratory allergy	13
reverse transcribed	13
methacholine challenge	13
common food	13
lipid mediators	13
new therapeutic	13
relatively small	13
elderly persons	13
clinical asthma	13
cytokine expression	13
medical conditions	13
soluble factors	13
viral pathogens	13
obstruktiven atemwegserkrankungen	13
bacterial products	13
im gegensatz	13
ten patients	13
children born	13
ground glass	13
asthma monitoring	13
cytokine responses	13
studies investigating	13
durch eine	13
symptoms among	13
study evaluating	13
new orleans	13
metered dose	13
function parameters	13
reduced expression	13
attention deficit	13
months later	13
children using	13
muscle hypertrophy	13
serum vitamin	13
fungal species	13
obese patients	13
nasopharyngeal aspirate	13
fl uid	13
infection induces	13
physician visits	13
normal values	13
nasal allergy	13
urinary antigen	13
cell numbers	13
obstruction group	13
two hours	13
mucus secretion	13
severe forms	13
controller medications	13
advanced lung	13
corticosteroid use	13
myocardial infarction	13
study reported	13
maternal asthma	13
wheezing disorders	13
ist der	13
molecular weight	13
asthma und	13
hae patients	13
exacerbation rate	13
indoor environmental	13
inhaled allergen	13
stem cell	13
reduced risk	13
i interferon	13
environmental allergens	13
childhood infections	13
organ involvement	13
antimicrobial peptides	13
children respiratory	13
people aged	13
asthma health	13
wall thickness	13
using flow	13
objective measures	13
die die	13
allergic responses	13
genetic predisposition	13
daily dose	13
type cytokines	13
severe ad	13
injectable epinephrine	13
patients presenting	13
mice received	13
disease remains	13
rescue intervention	13
clinical utility	13
bleomycin treated	13
newly diagnosed	13
causal relationship	13
bronchial wall	13
one month	13
sensitized patients	13
cell metaplasia	13
symptom onset	13
expert panel	13
environment interaction	13
economic burden	13
increased production	13
asthmatic symptoms	13
developed asthma	13
antiviral therapy	13
elimination diet	13
increased incidence	13
derived neurotoxin	13
lymphoid tissue	13
children treated	13
nucleic acid	12
european respiratory	12
rv replication	12
exacerbation rates	12
cell lysis	12
may prove	12
culture positive	12
respiratory morbidity	12
avian influenza	12
von cox	12
clinical evaluation	12
assess whether	12
first hospital	12
conductive ventilation	12
may become	12
increased significantly	12
systemic corticosteroid	12
mediated immunity	12
cytokine release	12
income countries	12
reg cd	12
dog dander	12
total aqol	12
periostin levels	12
many years	12
background asthma	12
um die	12
induced eosinophil	12
nasal swabs	12
vast majority	12
tlr agonists	12
pack year	12
allergy unit	12
nach der	12
obstruktiven bronchitiden	12
human eosinophil	12
appropriately sized	12
routine cta	12
severe equine	12
mit dem	12
south australia	12
cytokine chemokine	12
limited data	12
sinonasal tissue	12
local reactions	12
endotracheal intubation	12
weight gain	12
disease activity	12
inhaled budesonide	12
urban pm	12
arachidonic acid	12
mg dose	12
exercise group	12
without treatment	12
cell granzyme	12
para os	12
among asthmatic	12
oral provocation	12
venous blood	12
physical activity	12
mucosal inflammation	12
primary immunodeficiency	12
die il	12
allergischen erkrankungen	12
recently published	12
patients allergic	12
broad spectrum	12
must also	12
antiviral activity	12
airway responses	12
atopic individuals	12
stable copd	12
first study	12
care providers	12
impulse oscillometry	12
diagnosed artpah	12
poor quality	12
stent thrombosis	12
days following	12
studies reported	12
stat signalling	12
vergleich zu	12
complete blood	12
evaluated using	12
nitrogen oxides	12
difficulty breathing	12
reticular pattern	12
specific iga	12
binding capacity	12
events hour	12
sulfur dioxide	12
dose inhaled	12
whole genome	12
expression von	12
hedland pm	12
lung windows	12
respiratory disorders	12
pneumonia severity	12
inhaled fluticasone	12
test reactivity	12
cell degranulation	12
study drug	12
controlled studies	12
case control	12
second strategy	12
chronic exposure	12
adult population	12
asthma genetics	12
university first	12
well studied	12
patient days	12
significant associations	12
acute graft	12
sized donor	12
gene cd	12
frequently used	12
airway mucosa	12
excluded due	12
may allow	12
pitjantjatjara lands	12
bronchiolitis obliterans	12
respiratory muscle	12
allergic sensitisation	12
progressive dyspnoea	12
asm tone	12
pleural plaques	12
linear regression	12
left ventricular	12
intradermal skin	12
normal limits	12
ffm hydration	12
fatal asthma	12
lower risk	12
longer duration	12
vascular permeability	12
may impact	12
weeks smoking	12
prevent exacerbations	12
wheat flour	12
presenting cells	12
family size	12
gps recruited	12
asthmatic reactions	12
results data	12
training mwd	12
intradermal testing	12
lung inflation	12
receiver operator	12
lymphocyte count	12
acute lower	12
linked immunosorbent	12
children presenting	12
cig smoke	12
traditional chinese	12
study comparing	12
independently associated	12
male patient	12
cbt intervention	12
much less	12
cancer cases	12
severe asthmatics	12
dietary intake	12
baseline fev	12
torres strait	12
lower lung	12
status asthmaticus	12
mice exposed	12
peking university	12
primeiros anos	12
cd gene	12
subsequent childhood	12
underlying cause	12
total cost	12
based studies	12
th profile	12
persistent disease	12
cell receptor	12
significant increases	12
laboratory data	12
obstructive airway	12
aspirin sensitivity	12
positive tbb	12
lung tissues	12
infectious asthma	12
protective role	12
younger children	12
ebc nox	12
natural course	12
morning peak	12
fetal outcomes	12
early studies	12
methods subjects	12
ulcerative colitis	12
right diaphragm	12
resolution computed	12
old caucasian	12
late preterm	12
apnea syndrome	12
cbt group	12
tumour antigen	12
global lung	12
mucus hypersecretion	12
influenza infection	12
study aims	12
plasmacytoid dendritic	12
following training	12
pollen grains	12
predictive normal	12
cells via	12
congenital malformations	12
cypress pollen	12
olive tree	12
treatment protocol	12
levels may	12
mediator release	12
asthma onset	12
peanut allergens	12
caval shunt	12
care workers	12
nuclear export	12
pollen extract	12
test result	12
probably due	12
protease activity	12
via mdi	12
varying degrees	12
cell type	12
results show	12
splice variant	12
phagocytic function	12
becoming increasingly	12
wheezing illnesses	12
matrix metalloproteinase	12
high rate	12
patient population	12
tract disease	12
strategy recruited	12
experimental studies	12
pattern recognition	12
poor performance	12
human respiratory	12
viral coinfection	12
neutrophil elastase	12
serum albumin	12
laboratory findings	12
interview survey	12
activated mast	12
mean level	12
cancer risk	12
class ii	12
der akuten	12
tracheal mucus	12
including il	12
muscarinic receptor	12
respiratory samples	12
patient demographics	12
quality control	12
ultrasonic flow	12
well documented	12
preliminary results	12
dairy products	12
cells ml	12
lung parenchyma	12
molar mass	12
antiviral responses	12
significant effect	12
acting bronchodilator	12
related airway	12
clinical effectiveness	12
based cohort	12
unclear whether	11
mm hg	11
immune complexes	11
asthma symptom	11
skin symptoms	11
increasing doses	11
common variable	11
per se	11
oral antihistamines	11
early intervention	11
skin tested	11
phase three	11
patient showed	11
severe reactions	11
management strategies	11
sind die	11
asthma include	11
increased likelihood	11
may act	11
clinical findings	11
infancy predict	11
spontaneous urticaria	11
data support	11
infantile colic	11
flow meter	11
pulmonary edema	11
pediatric subjects	11
single gene	11
studies will	11
present within	11
antiviral response	11
exacerbate asthma	11
respiratory secretions	11
population sample	11
risk asthmatics	11
matched controls	11
total body	11
study suggest	11
patients following	11
medical treatment	11
host defense	11
disease may	11
children living	11
gel electrophoresis	11
wound healing	11
nan title	11
asthma affects	11
homeopathic remedies	11
high incidence	11
cytokine levels	11
ige igg	11
crossover study	11
zu einem	11
infectious disease	11
moderate severe	11
lamina propria	11
renal failure	11
minimum database	11
also affect	11
tumor growth	11
effects associated	11
exacerbated respiratory	11
numerous studies	11
dermatophagoides farinae	11
ml vs	11
zu den	11
murine models	11
genetic basis	11
strong th	11
asthmatic bronchial	11
prevent asthma	11
findings indicate	11
recombinant protein	11
patients included	11
muscle tissue	11
indoor allergens	11
age months	11
antibody response	11
airway disorders	11
specific th	11
wirkung der	11
immune diseases	11
study asthma	11
der obstruktiven	11
clinical disease	11
reduced asthma	11
significant adverse	11
additional asthma	11
asthma also	11
worsening asthma	11
inflammatory processes	11
clinical samples	11
emergency departments	11
subsequent asthma	11
several weeks	11
resistant asthma	11
immunodeficiency virus	11
retrospective analysis	11
including allergic	11
cat allergens	11
eine rolle	11
acute episodes	11
respiratory society	11
regulatory cells	11
natural colds	11
sleep medicine	11
strong association	11
eight patients	11
negative controls	11
die cox	11
life antibiotic	11
study investigating	11
blood ige	11
authors concluded	11
children infected	11
cell cultures	11
peach tree	11
eine reduzierte	11
bronchial smooth	11
fluticasone salmeterol	11
healthy horses	11
additional studies	11
interquartile range	11
activation test	11
threshold dose	11
also performed	11
stent implantation	11
community respiratory	11
female patient	11
neutrophil infiltration	11
functional significance	11
tissue eosinophils	11
cause airway	11
mucous membrane	11
inflammatory mechanisms	11
urine samples	11
different clinical	11
investigated whether	11
bowel disease	11
ocs use	11
tissue remodeling	11
diabetes mellitus	11
seminal fluid	11
samples taken	11
healthcare professionals	11
lung mechanics	11
nk cell	11
cold virus	11
negative impact	11
late phase	11
secondary outcomes	11
th day	11
observation group	11
fed infants	11
gamma ifn	11
well described	11
matched control	11
six patients	11
low cd	11
inflammation may	11
infected patients	11
conjugate vaccine	11
well understood	11
iga levels	11
fev vc	11
lung fibrosis	11
still unclear	11
modifiable factors	11
across different	11
resolution ct	11
blood cell	11
hr post	11
mean percentage	11
ist eine	11
pleural fl	11
current evidence	11
reflux disorders	11
biopsy revealed	11
old girl	11
th immunity	11
ige response	11
der regel	11
converting enzyme	11
increased use	11
several years	11
twin pairs	11
surfactant protein	11
recovery group	11
fully understood	11
patients diagnosed	11
higher concentrations	11
type inflammation	11
bacterial colonization	11
results demonstrate	11
randomized double	11
term asthma	11
major risk	11
coronary arteries	11
ophthalmic solution	11
lip swelling	11
treatment approaches	11
appropriate management	11
cochrane review	11
made available	11
viral wheeze	11
clinical picture	11
human monocyte	11
studies showing	11
derived growth	11
newly identified	11
sectional studies	11
viruses associated	11
subjects allergic	11
rahmen von	11
immunocap isac	11
single infection	11
sore throat	11
ild patients	11
old white	11
beobachtete man	11
pcn skin	11
drug therapy	11
normal levels	11
milk consumption	11
membrane thickening	11
among older	11
sialic acid	11
allergen specific	11
cam therapy	11
congestive heart	11
north america	11
neuraminidase inhibitors	11
cell populations	11
increasing prevalence	11
oxide levels	11
office visits	11
patients years	11
oral tolerance	11
conventional treatment	11
bone mineral	11
inflammatory properties	11
airways inflammation	11
increased release	11
expiratory airflow	11
mild intermittent	11
predict subsequent	11
immune systems	11
moderate persistent	11
lung fibroblasts	11
bronchial provocation	11
crucial role	11
airway inflammatory	11
seven patients	11
host response	11
low concentrations	11
eine wichtige	11
die wirkung	11
helicobacter pylori	11
ics therapy	11
high degree	11
using immunohistochemistry	11
allergen extracts	11
normal controls	11
positively correlated	11
allergic respiratory	11
early stage	11
gene transcription	10
und des	10
induced il	10
exacerbations per	10
recent data	10
enrolled children	10
may present	10
previously described	10
primeiros tempos	10
limited number	10
mometasone furoate	10
binding lectin	10
four groups	10
asthma study	10
inflammatory th	10
life respiratory	10
prospective longitudinal	10
physical exercise	10
controlled clinical	10
controller therapy	10
culture medium	10
normal epithelial	10
randomly selected	10
activated protein	10
sickle cell	10
respiratory outcomes	10
nasal provocation	10
common aeroallergens	10
previous study	10
hours later	10
increased rate	10
will provide	10
infection compared	10
ers ats	10
study suggests	10
develop asthma	10
atopic family	10
acute phase	10
elisa inhibition	10
allergen skin	10
detected virus	10
major role	10
eosinophil survival	10
related allergic	10
relative risk	10
cytokine response	10
urgent care	10
positive reactions	10
bronchodilator therapy	10
thrombin generation	10
study evaluated	10
tryptase levels	10
ocular itching	10
tissue repair	10
report describes	10
may involve	10
allergic individuals	10
eoe patients	10
tracheal wash	10
symptoms may	10
mediated cytotoxicity	10
blood levels	10
adversely affect	10
food allergen	10
immunoglobulin levels	10
mit den	10
perfil th	10
questionnaire survey	10
prevention program	10
molecular mass	10
also examined	10
childhood pneumonia	10
severe combined	10
disease process	10
tiotropium bromide	10
sedating antihistamines	10
also may	10
plasma cells	10
auch der	10
ventilation systems	10