trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram	frequency
in patients with	629
as well as	400
the development of	394
the role of	320
the use of	318
in children with	284
the presence of	278
the prevalence of	273
of asthma in	268
the effect of	267
years of age	262
respiratory syncytial virus	257
is associated with	257
the risk of	247
of patients with	244
patients with asthma	238
of asthma and	224
the most common	223
the treatment of	210
quality of life	204
been shown to	199
one of the	194
of this study	184
the number of	184
children with asthma	178
obstructive pulmonary disease	172
chronic obstructive pulmonary	169
was associated with	169
study was to	160
this study was	159
the aim of	157
a history of	154
there is a	153
there was a	150
there was no	149
in the first	146
associated with asthma	146
the diagnosis of	145
in this study	142
development of asthma	141
risk of asthma	139
to determine the	138
has been shown	135
are associated with	134
the united states	133
an increase in	133
asthma in the	131
in the united	129
of the patients	129
increased risk of	127
a total of	127
in addition to	125
in the treatment	124
it has been	124
the majority of	122
aim of this	121
been associated with	121
the effects of	120
of asthma exacerbations	120
respiratory tract infections	118
found to be	118
shown to be	116
the age of	116
exacerbations of asthma	115
in order to	115
lower respiratory tract	114
in the elderly	114
risk factor for	113
the pathogenesis of	113
a number of	112
associated with the	111
the severity of	111
associated with a	110
of children with	110
of the disease	110
compared to the	108
to evaluate the	108
prevalence of asthma	108
based on the	108
more likely to	107
be associated with	106
the incidence of	105
the level of	105
patients with severe	104
the relationship between	103
to be a	102
airway epithelial cells	102
the control group	101
exhaled nitric oxide	101
with asthma and	101
the management of	100
risk factors for	100
have shown that	99
role in the	99
has not been	97
respiratory tract infection	96
asthma exacerbations in	95
a systematic review	95
asthma in children	95
diagnosis of asthma	95
house dust mite	93
in the airways	93
of allergic rhinitis	93
according to the	93
in response to	93
bronchial epithelial cells	92
in lung function	91
due to the	90
was used to	89
the expression of	88
of childhood asthma	88
to assess the	88
with a history	87
in the development	86
year of life	84
for the treatment	84
associated with increased	83
the patient was	83
there were no	83
is the most	83
likely to be	83
the importance of	82
of the airway	82
related to the	81
a role in	81
the production of	81
the frequency of	81
to investigate the	80
a risk factor	80
for patients with	80
in early life	80
the impact of	80
first year of	79
years of life	78
the need for	78
the first year	78
the association between	77
with and without	77
have been shown	77
a diagnosis of	77
associated with an	77
in the pathogenesis	77
in children and	77
the absence of	76
upper respiratory tract	76
patients with chronic	76
patients with a	75
data suggest that	75
history of asthma	75
with severe asthma	75
in the airway	75
in the last	75
allergic rhinitis and	74
the release of	74
in the study	74
of lung function	74
the airway epithelium	73
a variety of	73
in young children	73
respiratory viral infections	73
is characterized by	72
studies have shown	72
the time of	72
the efficacy of	72
and severity of	72
of the study	72
in relation to	72
there is no	71
lung function in	71
airway smooth muscle	71
before and after	71
at least one	71
has also been	70
and treatment of	70
with or without	69
was found to	69
management of asthma	69
increase in the	68
part of the	68
specific ige to	67
asthma and allergic	67
viral infections in	67
the immune response	67
children and adults	67
family history of	67
and management of	66
asthma and allergy	66
contribute to the	66
a decrease in	66
a reduction in	66
during the first	66
to have a	66
be used to	66
asthma is a	65
in asthma and	65
airway inflammation in	65
such as the	65
skin prick tests	65
skin prick test	65
the end of	64
appears to be	64
of eosinophils in	64
in the lung	64
and risk of	64
months of age	63
of severe asthma	63
exacerbation of asthma	63
an important role	63
it is not	62
with allergic rhinitis	62
likely to have	61
the influence of	61
in terms of	61
has been reported	61
in adults with	61
lung function and	61
has been associated	61
is one of	60
supported by the	60
in the presence	60
to be the	60
changes in the	59
may be a	59
high levels of	59
play a role	59
a case of	59
thought to be	59
were associated with	59
compared with the	58
have been reported	58
at the time	58
included in the	58
the onset of	58
age of years	58
peak expiratory flow	58
is an important	58
a recent study	57
the study was	57
cells in the	57
in the absence	57
have also been	57
need to be	57
of the most	57
can be used	57
the association of	56
with asthma exacerbation	56
induced asthma exacerbations	56
may contribute to	56
as a result	56
shortness of breath	56
the first years	56
the case of	56
seems to be	56
airway inflammation and	56
the immune system	56
not associated with	56
in asthma exacerbations	56
important role in	55
the rate of	55
first years of	55
in the lungs	55
at years of	54
of respiratory viruses	54
the ability of	54
because of the	54
interstitial lung disease	54
the fact that	54
asthma and copd	54
an increased risk	54
natural history of	53
of lung cancer	53
we hypothesized that	53
to be associated	53
as compared to	53
a and b	52
systematic review and	52
the increase in	52
is thought to	52
of acute asthma	52
risk of developing	52
was a significant	52
was detected in	52
were found to	52
asthma exacerbations and	52
treatment of asthma	52
was observed in	51
and lung function	51
the results of	51
on the other	51
the hygiene hypothesis	51
the lack of	51
the diagnosis and	51
of the airways	51
and in the	51
in combination with	51
severity of asthma	51
effect on the	51
for the diagnosis	51
the patient had	51
found in the	51
in preschool children	50
to examine the	50
observed in the	50
to the development	50
significant difference in	50
involved in the	50
is important to	50
the course of	50
with an increased	50
a combination of	50
of the children	50
in asthmatic children	50
in those with	49
increase the risk	49
were more likely	49
exacerbations in children	49
of viral infections	49
of asthma control	49
children with a	49
the mean age	49
and the development	49
but not in	49
of asthma exacerbation	49
a range of	49
this is the	49
be due to	49
when compared to	48
mean age of	48
understanding of the	48
for the development	48
a result of	47
the general population	47
balb c mice	47
the other hand	47
the levels of	47
adults with asthma	47
the prevention of	47
of allergic diseases	47
it is important	47
diagnosis and treatment	47
immune response to	47
case of a	47
in association with	46
was defined as	46
the common cold	46
of these patients	46
to reduce the	46
aim was to	46
were found in	46
seasonal allergic rhinitis	45
with asthma exacerbations	45
an association between	45
in the control	45
were used to	45
to identify the	45
a study of	45
of the lung	45
patients with allergic	45
the degree of	45
of allergic disease	45
incidence of asthma	45
some of the	45
the most frequent	44
morbidity and mortality	44
in the management	44
prior to the	44
upper and lower	44
are likely to	44
and specific ige	44
of asthma symptoms	44
been found to	44
were included in	44
people with asthma	44
patients with copd	44
the identification of	44
the occurrence of	44
we report a	44
of asthma is	44
and asthma in	44
to years of	43
review and meta	43
review of the	43
mild to moderate	43
asthma in adults	43
have not been	43
role of viral	43
that there is	43
should be considered	43
in early childhood	43
significantly higher in	43
in our study	43
may not be	43
analysis of the	42
significantly associated with	42
needs to be	42
for asthma in	42
diagnosis and management	42
no difference in	42
most of the	42
the natural history	42
symptoms of asthma	42
from patients with	42
of airway inflammation	42
well as the	42
poor asthma control	42
acute exacerbations of	42
viral respiratory infections	42
serum levels of	42
no significant difference	42
between the two	42
higher risk of	42
in infants and	42
and allergic rhinitis	41
eosinophils in the	41
a lack of	41
idiopathic pulmonary fibrosis	41
in the past	41
acute asthma exacerbations	41
studies are needed	41
can lead to	41
in older adults	41
as part of	41
is the first	41
the airways of	41
of the respiratory	41
a year old	41
difference in the	41
we found that	41
th and th	41
factor for asthma	41
for at least	41
for asthma and	41
syncytial virus infection	41
in acute asthma	41
at the age	40
was no significant	40
did not have	40
was to evaluate	40
in the prevalence	40
adults and children	40
is likely to	40
factors such as	40
there are no	40
patients with mild	40
thymic stromal lymphopoietin	40
may also be	40
were observed in	40
are needed to	40
asm cells from	40
may lead to	40
a cohort of	40
any of the	40
at age years	40
these data suggest	40
there has been	39
have been associated	39
the percentage of	39
the objective of	39
a prospective study	39
significant increase in	39
and development of	39
respiratory viruses in	39
number of patients	39
of life and	39
in the same	38
of food allergy	38
and asthma exacerbations	38
of the immune	38
with cystic fibrosis	38
of asthma was	38
in asthmatic patients	38
allergy and asthma	38
was found in	38
the most important	38
randomized controlled trial	38
birth cohort study	38
role of the	38
the effectiveness of	38
responsible for the	38
results of the	38
used as a	38
forced expiratory volume	38
the basis of	38
is known to	38
in the group	37
known to be	37
our aim was	37
in accordance with	37
than in the	37
a group of	37
with asthma in	37
aged to years	37
a significant increase	37
in contrast to	37
obstructive sleep apnea	37
epithelial cells and	37
to compare the	37
been reported in	37
patients treated with	37
the bone marrow	36
this is a	36
reported to be	36
more than one	36
has been demonstrated	36
differences in the	36
in all patients	36
a patient with	36
play an important	36
asthma symptoms and	36
major basic protein	36
were measured by	36
present in the	36
in the diagnosis	36
was the most	36
for treatment of	35
diseases such as	35
prevalence of allergic	35
development of allergic	35
with a mean	35
depending on the	35
was treated with	35
in these patients	35
expiratory volume in	35
respiratory distress syndrome	35
up to of	35
sick building syndrome	35
in adults and	35
data from the	35
on the basis	35
we present a	35
asthma has been	35
the patients were	35
to be more	35
the ability to	35
asma j pinto	35
been implicated in	35
da asma j	35
reduction in the	35
may have a	35
j pinto mendes	35
the same time	35
the combination of	35
with respect to	35
considered to be	35
in a recent	35
air pollution and	35
been reported to	34
the inflammatory response	34
appear to be	34
found to have	34
from donors with	34
specific ige and	34
higher in the	34
use of a	34
cells from donors	34
the likelihood of	34
polymerase chain reaction	34
was measured by	34
asthma exacerbation in	34
no significant differences	34
of bronchial asthma	34
found that the	34
were detected in	34
at baseline and	34
a review of	34
and asthma control	34
it is possible	34
with a diagnosis	34
of respiratory syncytial	34
syncytial virus bronchiolitis	34
length of stay	34
of chronic obstructive	34
of the asthma	33
history of atopy	33
the study of	33
the administration of	33
the duration of	33
the cause of	33
global initiative for	33
is needed to	33
viral infection and	33
objective of this	33
such as asthma	33
study of asthma	33
evaluation of the	33
study showed that	33
were significantly higher	33
of health and	33
has been used	33
factors associated with	33
it is also	33
asthma and allergies	33
subjects with asthma	33
early in life	33
moderate to severe	33
an improvement in	33
is related to	33
is a major	33
controlled trial of	33
the setting of	33
addition to the	33
specific ige levels	33
the response to	33
in case of	33
asthmatic and non	33
many of the	32
efficacy and safety	32
this may be	32
transforming growth factor	32
of sensitization to	32
in both groups	32
infections in the	32
have demonstrated that	32
the lower respiratory	32
cohort study of	32
of developing asthma	32
were treated with	32
safe and effective	32
the respiratory system	32
pathogenesis of asthma	32
has been found	32
and allergic disease	32
with acute asthma	32
of inhaled corticosteroids	32
with the development	32
at the same	32
study of children	32
results suggest that	32
in the nasal	32
that patients with	32
cause of death	32
but it is	32
in the setting	32
in the context	32
correlation between the	32
it can be	32
the context of	32
were no significant	32
one or more	31
we did not	31
can also be	31
asthma control and	31
the two groups	31
the group of	31
world health organization	31
asthma during pregnancy	31
at high risk	31
and duration of	31
report a case	31
t cells and	31
in the previous	31
in nasal polyps	31
viral infection in	31
study of the	31
the possibility of	31
patients who were	31
response to treatment	31
and without asthma	31
and may be	31
children with acute	31
is increased in	31
increased levels of	31
role in asthma	31
is defined as	31
inflammation in asthma	31
the mechanism of	31
end of the	31
compared to those	31
to study the	31
of patients who	31
change from baseline	31
levels in the	31
expression of the	30
the placebo group	30
infection in the	30
in subjects with	30
factors for asthma	30
an asthma exacerbation	30
in primary care	30
more than of	30
is a common	30
randomized controlled trials	30
was to determine	30
of allergy and	30
allergic airway inflammation	30
compared to placebo	30
the purpose of	30
adult patients with	30
the hypothesis that	30
bronchiolitis in infancy	30
to play a	30
lung function testing	30
a positive correlation	30
may play a	30
epithelial cells in	30
was shown to	30
prevention of asthma	30
be involved in	30
total ige levels	30
were able to	30
who did not	30
may be due	30
asthma in childhood	30
to determine if	30
inflammation in the	30
of age and	30
of the cases	30
control of asthma	30
in a study	30
associated with respiratory	30
to house dust	30
a family history	30
the most frequently	30
asthma and chronic	30
infections in children	30
in recent years	29
effects on the	29
the addition of	29
has been suggested	29
of atopic dermatitis	29
asthma and atopy	29
low birth weight	29
experimental rhinovirus infection	29
for the first	29
in peripheral blood	29
reported in the	29
tumor necrosis factor	29
are known to	29
are more likely	29
been linked to	29
viral respiratory tract	29
cd t cells	29
was to assess	29
lead to the	29
with chronic obstructive	29
in hong kong	29
and there is	29
to be effective	29
respiratory infections in	29
the proportion of	29
has been identified	29
peripheral blood mononuclear	29
was significantly higher	29
the patient is	29
in severe asthma	29
innate immune response	29
fold increase in	29
and environmental factors	29
significant differences in	29
acute exacerbation of	29
in this group	29
impact on the	29
response to the	29
have been identified	29
in asthma patients	29
due to asthma	29
in horses with	29
suggest that the	29
in the case	29
the respiratory tract	29
may be associated	29
severe persistent asthma	29
there are several	29
that of the	29
of vitamin d	29
for the prevention	29
treatment of acute	29
be related to	29
and quality of	29
guidelines for the	29
in exacerbations of	29
viral infections and	29
for asthma exacerbations	29
we report the	29
in of the	28
initiative for asthma	28
and can be	28
were the most	28
studies suggest that	28
infection in children	28
remains to be	28
and lower respiratory	28
by flow cytometry	28
mean age was	28
reduce the risk	28
patients had a	28
the formation of	28
the present study	28
was measured in	28
all patients with	28
study aimed to	28
a mouse model	28
in clinical practice	28
respiratory viral infection	28
early life and	28
were exposed to	28
use of the	28
treatment of allergic	28
the emergency department	28
have been found	28
findings suggest that	28
to determine whether	28
blood mononuclear cells	28
of air pollution	28
rhinitis and asthma	28
group of patients	28
the concentration of	28
and allergic diseases	28
the most commonly	28
asthma exacerbations are	28
systematic review of	28
with respiratory tract	28
of patients were	28
our understanding of	28
in pregnant women	28
were sensitized to	28
pregnant women with	28
the symptoms of	28
asthma and other	28
consistent with the	28
granzyme b expression	28
on lung function	28
significantly higher than	28
was no difference	28
and safety of	28
symptoms in the	28
also known as	28
of exhaled nitric	28
this study is	28
similar to those	27
be used as	27
a birth cohort	27
as measured by	27
of asthma patients	27
more common in	27
in which the	27
was able to	27
rhinovirus genome load	27
cd and cd	27
in vitro and	27
are thought to	27
in a mouse	27
in asthmatic subjects	27
increased risk for	27
did not differ	27
no effect on	27
the result of	27
of the lungs	27
the united kingdom	27
is based on	27
in patients who	27
that asthma is	27
in infants with	27
this age group	27
genetic and environmental	27
of exposure to	27
are related to	27
in the number	27
release of il	27
house dust mites	27
the safety of	27
may result in	27
were randomized to	27
in cases of	27
and of the	27
cytokines and chemokines	27
also associated with	27
respiratory symptoms in	27
of infants with	27
american thoracic society	27
children and adolescents	26
high risk of	26
recurrent airway obstruction	26
and exacerbations of	26
the assessment of	26
there have been	26
a statistically significant	26
body mass index	26
higher levels of	26
acute asthma exacerbation	26
in asthma pathogenesis	26
none of the	26
the last months	26
in a cohort	26
with atopic dermatitis	26
the introduction of	26
patients with moderate	26
showed that the	26
is difficult to	26
at the end	26
we aimed to	26
the pathophysiology of	26
chronic respiratory diseases	26
yet to be	26
at risk of	26
between the groups	26
and response to	26
of asthma or	26
as a risk	26
the detection of	26
patients who have	26
in the clinical	26
of symptoms and	26
majority of the	26
and patients with	26
of asthmatic patients	26
severity of the	26
patients in the	26
development of the	26
in airway epithelial	26
tract infections in	26
eosinophil cationic protein	26
has been described	26
asthma in pregnancy	26
significant reduction in	26
intensive care unit	26
and atopic dermatitis	26
the mechanisms of	26
risk of childhood	26
the previous months	26
which may be	26
respiratory viruses and	26
and those with	26
most common cause	26
were positive for	26
to that of	26
associated with higher	26
those with a	26
conflict of interest	26
asthma symptoms in	26
a role for	26
department of health	26
young children with	26
change in fev	25
can result in	25
prospective study of	25
and it is	25
is a chronic	25
in the literature	25
of allergic sensitization	25
there was an	25
and mortality in	25
significant improvement in	25
well as a	25
virus infection in	25
of asthmatic children	25
randomised controlled trial	25
younger than years	25
aim of the	25
patient had a	25
of the upper	25
was well tolerated	25
in of patients	25
in the placebo	25
from birth to	25
health and disease	25
the most prevalent	25
asthma and asthma	25
was supported by	25
signs and symptoms	25
in the early	25
used in the	25
for children with	25
respiratory infections and	25
risk for asthma	25
of specific ige	25
in the bronchial	25
severe asthma and	25
the potential to	25
or absence of	25
the amount of	25
other respiratory viruses	25
diagnosed with asthma	25
with bronchial asthma	25
are the most	25
the activation of	25
by age years	25
correlated with the	25
is common in	25
when compared with	25
the university of	25
it is a	25
months of life	25
of house dust	25
of which are	25
have been described	25
part of a	25
of allergic asthma	25
cause of asthma	24
in line with	24
evidence of a	24
women with asthma	24
mouse model of	24
of eosinophils and	24
subsequent development of	24
was higher in	24
little is known	24
airway obstruction in	24
to understand the	24
leading cause of	24
are responsible for	24
and the risk	24
patients with acute	24
with increased risk	24
over the last	24
supported by nhmrc	24
should not be	24
in a single	24
in the second	24
wheezing and asthma	24
a significant difference	24
to increase the	24
such as il	24
the dose of	24
be considered in	24
has been observed	24
a mean age	24
better understanding of	24
of viral infection	24
prevention and treatment	24
fev fvc ratio	24
and severe asthma	24
is responsible for	24
mast cells and	24
was significantly associated	24
wide range of	24
the form of	24
with asthma or	24
this was a	24
in the general	24
had at least	24
shown that the	24
asthma control medication	24
accordance with the	24
was assessed by	24
forced oscillation technique	24
sensitivity and specificity	24
the etiology of	24
of the clinical	24
the differential diagnosis	24
azelastine nasal spray	24
of the two	24
of viral respiratory	24
being the most	24
ranged from to	24
of subjects with	24
human airway epithelial	24
presence or absence	24
the pattern of	24
with inhaled corticosteroids	24
were performed using	24
of respiratory disease	24
the asthma control	24
that may be	24
the first time	24
common cause of	24
results there were	24
asthma at age	24
a randomized controlled	23
were higher in	23
course of the	23
fractional exhaled nitric	23
the lower airways	23
respiratory tract symptoms	23
sleep disordered breathing	23
inflammation of the	23
due to its	23
higher prevalence of	23
asthma by age	23
is a risk	23
was referred to	23
of respiratory tract	23
children who had	23
was obtained from	23
asthma and the	23
with the control	23
increased prevalence of	23
all patients were	23
in copd patients	23
led to the	23
there is evidence	23
to contribute to	23
that can be	23
is possible that	23
studies have demonstrated	23
severe asthma exacerbations	23
environmental tobacco smoke	23
detected in the	23
exposure to environmental	23
had a history	23
the burden of	23
dust mite allergen	23
is a high	23
and or asthma	23
is a need	23
of more than	23
elevated levels of	23
that it is	23
and has been	23
be responsible for	23
is known about	23
that have been	23
were obtained from	23
atopic dermatitis and	23
increases the risk	23
depends on the	23
were collected from	23
were asked to	23
of the first	23
measured by elisa	23
levels were significantly	23
and bronchoalveolar lavage	23
results in the	23
at the beginning	23
of the population	23
the potential for	23
these results suggest	23
chronic lung disease	23
in the community	23
caused by the	23
associated with severe	23
to be an	23
was performed to	23
a significant reduction	23
the relationship of	23
on the development	23
infections in exacerbations	23
children with severe	23
patients with the	23
the past months	23
in more than	23
wheezing in the	23
in comparison to	23
is a rare	23
and childhood asthma	23
study is to	23
in lung tissue	23
used as an	23
obtained from the	23
the last year	23
lead to a	23
this study aimed	23
and airway hyperresponsiveness	23
use of inhaled	23
compared with those	23
be explained by	23
with a higher	23
compared with placebo	23
defined as a	23
infections and asthma	23
been identified as	23
based on a	23
a comparison of	23
be a useful	23
asthma control test	23
well as in	22
was not associated	22
is a significant	22
otitis media with	22
has recently been	22
the availability of	22
than those with	22
the contribution of	22
of the human	22
levels of il	22
allergic rhinitis in	22
of treatment with	22
to patients with	22
to estimate the	22
written informed consent	22
a positive skin	22
in the asthmatic	22
to years old	22
than that of	22
in lung cancer	22
community study of	22
children in the	22
purpose of this	22
at least in	22
with stable asthma	22
of the patient	22
seen in the	22
regulatory t cells	22
of role of	22
to improve the	22
the beginning of	22
function in the	22
in people with	22
due to a	22
for childhood asthma	22
with mild asthma	22
the goal of	22
were measured using	22
was to examine	22
of which were	22
symptoms such as	22
major cause of	22
total of patients	22
media with effusion	22
hypothesized that the	22
was used for	22
in the form	22
children younger than	22
severe asthma in	22
study of role	22
in some cases	22
can be detected	22
a period of	22
carried out in	22
been shown that	22
acute respiratory tract	22
allergic diseases in	22
increased in the	22
in the upper	22
in this age	22
the fi rst	22
the patients with	22
first months of	22
disease in the	22
the outcomes of	22
be effective in	22
was performed with	22
decrease in the	22
evidence for a	22
role of eosinophils	22
and exposure to	22
of a number	22
was to investigate	22
with regard to	22
the regulation of	22
inhaled corticosteroids in	22
be used in	22
as an alternative	22
the lungs of	22
for asthma management	22
large number of	22
test was used	22
be considered for	22
a feature of	22
higher in patients	22
we have previously	22
in general practice	22
acute and chronic	22
was carried out	22
used to assess	22
a better understanding	22
in one study	21
in most cases	21
did not affect	21
referred to as	21
suggests that the	21
older than years	21
forced vital capacity	21
function of the	21
to be increased	21
in allergic asthma	21
of children and	21
of asthma at	21
one year of	21
lung cancer cells	21
of mast cells	21
has led to	21
with an increase	21
also been shown	21
pulmonary function testing	21
in some patients	21
to develop a	21
innate and adaptive	21
positive skin test	21
of the il	21
and respiratory symptoms	21
bronchoalveolar lavage fluid	21
and is a	21
with more severe	21
increase in il	21
especially in the	21
presented with a	21
in another study	21
atopic dermatitis in	21
in both the	21
tract infection in	21
with asthma are	21
production of il	21
and have been	21
is not a	21
year old children	21
kipyv and wupyv	21
seem to be	21
strongly associated with	21
at increased risk	21
asthma control in	21
included in this	21
with acute respiratory	21
two years of	21
small number of	21
of cases of	21
and that the	21
recent studies have	21
in children aged	21
a wide range	21
in the pediatric	21
was diagnosed with	21
identified as a	21
strategy for asthma	21
was to compare	21
of response to	21
and healthy controls	21
at months of	21
triggers of asthma	21
childhood asthma and	21
and associated with	21
and in vivo	21
high prevalence of	21
acute respiratory illness	21
with copd and	21
further studies are	21
between and years	21
and should be	21
cytokines such as	21
is caused by	21
evidence suggests that	21
lower levels of	21
the innate immune	21
the last years	21
the progression of	21
of bronchial epithelial	21
children aged to	21
of the total	21
the first months	21
infants and children	21
majority of patients	21
a consequence of	21
acute respiratory distress	21
tests were positive	21
asthma action plan	21
have been implicated	21
the risk for	21
there are few	21
the initiation of	21
was conducted in	21
especially in children	21
within the first	21
are found in	21
asthma development in	21
been diagnosed with	21
of life was	20
increased expression of	20
there is an	20
from baseline in	20
may be the	20
no differences were	20
males and females	20
the sensitivity of	20
and release of	20
years and over	20
the primary outcome	20
it is likely	20
in this population	20
copd and bronchiectasis	20
blood eosinophil counts	20
at this time	20
analyses were performed	20
airway hyperresponsiveness and	20
studies on the	20
for use in	20
do not have	20
elderly asthmatic patients	20
mrna expression of	20
asthma and atopic	20
leads to a	20
of asthma by	20
than years of	20
serum ige levels	20
association between the	20
leukotriene receptor antagonists	20
subjects with copd	20
a subset of	20
age of the	20
even in the	20
of life questionnaire	20
been observed in	20
with an asthma	20
after weeks of	20
implicated in the	20
during pregnancy and	20
most likely to	20
the efficacy and	20
food allergy in	20
the magnitude of	20
a marker of	20
that exposure to	20
and chronic obstructive	20
the forced oscillation	20
has been a	20
allergic rhinitis is	20
analysis was performed	20
development of childhood	20
infants and young	20
b expression in	20
in chronic obstructive	20
of airflow obstruction	20
data on the	20
results in a	20
the induction of	20
effect of tezepelumab	20
granzyme b and	20
in the lower	20
a higher risk	20
in the immune	20
and pulmonary function	20
a pilot study	20
prospective cohort study	20
development of a	20
associated with more	20
characteristics of the	20
of acute respiratory	20
the control of	20
an acute asthma	20
effect of a	20
is not known	20
global strategy for	20
mild persistent asthma	20
reactive oxygen species	20
with atopic asthma	20
and allergies in	20
of asthma has	20
the treatment group	20
that has been	20
asthma is the	20
asthma in older	20
research is needed	20
human metapneumovirus infection	20
used to treat	20
and blood institute	20
is due to	20
been described in	20
from subjects with	20
more effective than	20
skin prick testing	20
and young children	20
members of the	20
syncytial virus in	20
components of the	20
a key role	20
asthma medication use	20
which can be	20
intercellular adhesion molecule	20
of the same	20
ige levels and	20
positive airway pressure	20
more susceptible to	20
results from the	20
chronic respiratory disease	20
two or more	20
has been implicated	19
and specificity of	19
of recurrent wheezing	19
to elucidate the	19
it is unknown	19
clinical characteristics of	19
with food allergy	19
patients who are	19
may be used	19
positive correlation between	19
in allergic rhinitis	19
the existence of	19
characterized by a	19
after adjusting for	19
improvement in lung	19
a significant decrease	19
the upper respiratory	19
vitamin d deficiency	19
management and prevention	19
cases of asthma	19
of the allergic	19
positive skin prick	19
its role in	19
in a randomized	19
of peripheral blood	19
were negative for	19
of all patients	19
primary prevention of	19
were diagnosed with	19
increase in airway	19
associated with airway	19
referred to our	19
of the literature	19
led to a	19
less than years	19
atopy and asthma	19
vitamin d levels	19
are present in	19
asthma may be	19
it is clear	19
in the future	19
during the study	19
for the management	19
lung function impairment	19
of the eosinophil	19
all of the	19
virus bronchiolitis in	19
we examined the	19
with a high	19
of morbidity and	19
higher than the	19
and found that	19
severe respiratory syncytial	19
a significant role	19
a reduction of	19
decline in lung	19
participants in the	19
of our study	19
was confirmed by	19
vitro and in	19
and to determine	19
the decrease in	19
children hospitalized for	19
was positive in	19
with lung cancer	19
pulmonary function tests	19
may be useful	19
between patients with	19
elderly patients with	19
the nasal mucosa	19
with respiratory syncytial	19
the disease and	19
year history of	19
used for the	19
the inclusion criteria	19
early childhood asthma	19
in childhood asthma	19
patients who had	19
of inflammatory cells	19
compared to healthy	19
wheezing in children	19
in copd and	19
the quality of	19
were divided into	19
should also be	19
of the th	19
children to years	19
an acute exacerbation	19
resulted in a	19
it may be	19
should be used	19
asthma severity and	19
all of them	19
allergic bronchopulmonary aspergillosis	19
in the majority	19
are consistent with	19
recruitment to the	19
to the control	19
associated with lower	19
from to years	19
were seen in	19
the prevalence and	19
international study of	19
respiratory pathogens in	19
food allergy and	19
of the treatment	19
innate lymphoid cells	19
in a large	19
and asthma severity	19
pulmonary function in	19
lung disease and	19
presence of eosinophils	19
british thoracic society	19
higher than that	19
obstructive lung disease	19
be important in	19
with lower respiratory	19
defined as the	19
improvement in the	19
national health and	18
viral and bacterial	18
asthma management and	18
of patients in	18
response in the	18
was performed in	18
related quality of	18
significant role in	18
levels of the	18
retrospective chart review	18
for the study	18
rhinovirus infection in	18
induced asthma exacerbation	18
primary and secondary	18
shown to have	18
to be considered	18
the children with	18
lung cancer and	18
in the s	18
some of these	18
severe acute respiratory	18
the discovery of	18
safety and efficacy	18
to be at	18
with severe ea	18
patients with crs	18
no change in	18
of symptoms of	18
frequency of asthma	18
to viral infections	18
there may be	18
and asthma symptoms	18
influenza vaccination in	18
in a patient	18
should be performed	18
virus infection and	18
less likely to	18
eo b cfu	18
which is a	18
response to inhaled	18
compared with control	18
there is also	18
exhaled breath condensate	18
sensitization to cat	18
which in turn	18
presence of a	18
and children with	18
differences between the	18
will be used	18
in induced sputum	18
the world health	18
response to infection	18
be caused by	18
be a risk	18
in a group	18
aged years and	18
total serum ige	18
needed to determine	18
of age with	18
gene expression in	18
had a positive	18
onset of asthma	18
result of the	18
improvement in asthma	18
asthma exacerbation and	18
patients have been	18
to participate in	18
with mild to	18
of them were	18
associated with chronic	18
in infancy and	18
more prevalent in	18
use of antibiotics	18
is also a	18
in asthmatic airways	18
no correlation between	18
few studies have	18
infection and asthma	18
the national health	18
the involvement of	18
with viral infection	18
among patients with	18
higher incidence of	18
a subgroup of	18
risk of allergic	18
was evaluated by	18
in a clinical	18
had no effect	18
airways of asthmatics	18
a need for	18
were no differences	18
of less than	18
the presence or	18
of current asthma	18
the patients had	18
history of allergic	18
children with respiratory	18
pulmonary function and	18
an average of	18
asthma and wheezing	18
asthma control questionnaire	18
present a case	18
we conclude that	18
chart review of	18
in the blood	18
with a positive	18
completed the study	18
patients should be	18
in which a	18
in children in	18
of cd cd	18
igg and igg	18
asthma can be	18
was present in	18
on chromosome q	18
have been studied	18
to confirm these	18
was determined by	18
we sought to	18
to the emergency	18
have been observed	18
for more than	18
to have an	18
in this case	18
used to identify	18
be able to	18
difference between the	18
at least months	18
is clear that	18
was started on	17
in the us	17
to be important	17
the possibility that	17
the concept of	17
gastroesophageal reflux disease	17
in comparison with	17
this type of	17
is not well	17
during an acute	17
children with atopic	17
in any of	17
viral respiratory infection	17
allergies in childhood	17
that in the	17
minutes after the	17
have a higher	17
neutrophilic airway inflammation	17
significant difference between	17
also play a	17
low levels of	17
no evidence of	17
detected in of	17
allergy clin immunol	17
nitric oxide in	17
and tolerability of	17
f e no	17
history of recurrent	17
the grass pollen	17
of the subjects	17
patients suffering from	17
and allergy at	17
the evaluation of	17
serum total ige	17
by means of	17
in bronchial epithelial	17
and it was	17
of inhaled corticosteroid	17
of the allergen	17
were determined by	17
primary ciliary dyskinesia	17
asthma is not	17
in conjunction with	17
the patients who	17
with allergic asthma	17
a t h	17
in the home	17
asthma have been	17
study was conducted	17
are the major	17
of respiratory symptoms	17
for development of	17
the type of	17
similar to that	17
was measured using	17
key role in	17
health and nutrition	17
may be related	17
of proinflammatory cytokines	17
significantly increased in	17
studies that have	17
the persistence of	17
recurrent wheezing and	17
was an increase	17
children who were	17
high risk for	17
a protective effect	17
in children younger	17
a retrospective study	17
year of age	17
patients with seasonal	17
we describe a	17
of this disease	17
study of patients	17
nature of the	17
there is little	17
effects of the	17
the development and	17
to infection with	17
its impact on	17
asthma control is	17
outdoor air pollution	17
and ara h	17
the analysis of	17
prick tests with	17
emergency department visits	17
of a positive	17
asthma quality of	17
and is associated	17
important in the	17
the ages of	17
and use of	17
is likely that	17
in a population	17
volatile organic compounds	17
with asthma severity	17
and after the	17
and respiratory syncytial	17
pathophysiology of asthma	17
effect of the	17
of life in	17
patients with persistent	17
to complete a	17
risk of severe	17
found in patients	17
could be a	17
duration of asthma	17
with a significant	17
the rates of	17
of asthma are	17
respiratory symptoms and	17
to respond to	17
time of the	17
the outcome of	17
a randomised controlled	17
those who were	17
it is the	17
studies have been	17
such as those	17
occurring in the	17
may be involved	17
with asthma have	17
of interstitial lung	17
derived from the	17
mrna expression was	17
j allergy clin	17
samples were collected	17
and characteristics of	17
oral food challenge	17
innate immune responses	17
the international recommendations	17
nasal epithelial cells	17
and the use	17
the safety and	17
in the field	17
a patient who	17
ige and igg	17
the first strategy	17
been suggested that	17
were randomized into	17
had a mean	17
into two groups	17
of patients had	17
in the fall	17
response to viral	17
to our knowledge	17
the recruitment of	17
genes associated with	17
often associated with	17
and peak flow	17
associated with reduced	17
indoor air quality	17
asthma in a	17
months after the	17
a literature review	17
for detection of	17
epithelial cells from	16
t h type	16
study found that	16
increased susceptibility to	16
was related to	16
composition of the	16
of those who	16
and asthma and	16
a viral infection	16
disease in children	16
than that in	16
asthma at years	16
a dose of	16
of atopy and	16
is the only	16
immune responses in	16
in the third	16
months prior to	16
and efficacy of	16
positive control cells	16
in allergic patients	16
patients sensitized to	16
of a new	16
there were significant	16
national institutes of	16
is necessary to	16
asthma education and	16
is present in	16
been found in	16
the potential of	16
the airways and	16
parts of the	16
were carried out	16
was not significantly	16
not significantly different	16
of the major	16
asthma candidate genes	16
the implementation of	16
with chronic respiratory	16
levels of total	16
to high levels	16
associated with viral	16
of the lower	16
morning and evening	16
and a decrease	16
the intervention group	16
were analyzed by	16
am phagocytic ability	16
of asthma during	16
expression of il	16
development of sensitization	16
asthma as a	16
in the respiratory	16
different types of	16
we conducted a	16
respiratory disease in	16
results showed that	16
be present in	16
a high prevalence	16
in the present	16
high level of	16
donors with and	16
rate of asthma	16
potential role of	16
divided into two	16
to affect the	16
viral infections are	16
by asm cells	16
allergic airway disease	16
found between the	16
im rahmen der	16
and at the	16
be the most	16
and did not	16
of the symptoms	16
of the hygiene	16
of sbs symptoms	16
by the patient	16
the change in	16
the activity of	16
inflammatory airway disease	16
t cells in	16
wide variety of	16
the utility of	16
of asm cells	16
respiratory viruses were	16
prevalence of respiratory	16
a large number	16
is unknown whether	16
from the first	16
both asthma and	16
lung cancer cell	16
deficit hyperactivity disorder	16
high fat meal	16
associated with wheezing	16
pulmonary blood flow	16
more than years	16
in blood and	16
leading to the	16
other allergic diseases	16
with respiratory disease	16
is able to	16
followed by a	16
tree nut allergy	16
in cystic fibrosis	16
circulating h cit	16
and total ige	16
half of the	16
expression in blood	16
with the highest	16
of respiratory pathogens	16
as in the	16
it should be	16
of an asthma	16
the severity and	16
higher than in	16
the measurement of	16
at least two	16
in vitro studies	16
area under the	16
are able to	16
with the diagnosis	16
an allergic reaction	16
lung function tests	16
asthma or copd	16
sputum eosinophil counts	16
is essential to	16
and eczema in	16
of inflammation in	16
with asthma were	16
this study we	16
assessment of the	16
for allergic rhinitis	16
logistic regression analysis	16
mycoplasma pneumoniae and	16
for up to	16
chronic lung diseases	16
were measured in	16
significant decrease in	16
we present the	16
is similar to	16
to a significant	16
on the airway	16
horses with severe	16
patients with idiopathic	16
and prevention of	16
total ige and	16
acute asthma in	16
plays a role	16
has shown that	16
in agreement with	16
the pediatric population	16
is a complex	16
levels of ige	16
studies have investigated	16
a clinical trial	16
these findings suggest	16
and prevalence of	16
data were analysed	16
differences were found	16
the gold standard	16
we describe the	16
functional residual capacity	16
at risk for	16
in individuals with	16
and years of	16
will be discussed	16
and th cytokine	16
were used as	16
with persistent asthma	16
serum specific ige	16
suggesting that the	16
tend to be	16
to confirm the	16
over the past	16
total ige level	16
in a range	16
suggested that the	16
on the severity	16
contributes to the	16
to be determined	16
the correlation between	16
weeks of treatment	16
are exposed to	16
to severe asthma	16
results of a	16
patients did not	16
of at least	16
of inflammatory mediators	16
investigate the effect	16
the first case	16
only of the	16
cells and monocytes	16
groups of patients	16
several studies have	15
a higher prevalence	15
consent was obtained	15
study on the	15
grass pollen allergy	15
of adults with	15
closely related to	15
to treatment with	15
activation of the	15
as a consequence	15
old woman with	15
variation in the	15
of the virus	15
commonly used in	15
the value of	15
in adult patients	15
with moderate to	15
the adult and	15
randomized clinical trial	15
were conducted at	15
be required to	15
exposure to allergens	15
of upper respiratory	15
had a higher	15
therapy in asthma	15
to be involved	15
was significantly increased	15
we aim to	15
the pollen season	15
significant reductions in	15
more frequent in	15
role for eosinophils	15
immune system and	15
was significant for	15
prevalence of sbs	15
and up to	15
some studies have	15
the patient presented	15
t cell responses	15
allergic sensitization and	15
be considered as	15
in the bone	15
treatment for the	15
observational study of	15
peripheral blood eosinophils	15
also found that	15
who had not	15
in the skin	15
in children who	15
of the innate	15
the upper airways	15
rhinovirus illnesses in	15
of these studies	15
to identify and	15
in the regulation	15
is required to	15
a retrospective chart	15
with disease severity	15
used to determine	15
the process of	15
symptoms of allergic	15
is important for	15
one third of	15
patients were included	15
group of children	15
infl uenza a	15
a prospective cohort	15
of wheezing in	15
dose of inhaled	15
to moderate asthma	15
increased in asthma	15
patients with covid	15
pediatric patients with	15
be useful in	15
immune responses to	15
to viral infection	15
suggest that there	15
of persistent asthma	15
hypersensitivity reactions to	15
up to mg	15
may be more	15
cd cd high	15
no statistically significant	15
disease control and	15
were identified in	15
failure to thrive	15
treatment of the	15
of the bronchial	15
a difference in	15
the lower airway	15
in airway inflammation	15
continuous positive airway	15
in the uk	15
and fev fvc	15
and changes in	15
levels of ecp	15
comparison of the	15
for disease control	15
with seasonal allergic	15
believed to be	15
percentage change in	15
among children with	15
lung disease in	15
asthma associated with	15
allergy at age	15
the extent of	15
severe asthma with	15
the characteristics of	15
a course of	15
asthma with fungal	15
were years of	15
to a lesser	15
may be important	15
nitric oxide and	15
epidermal growth factor	15
grass pollen season	15
for the same	15
a panel of	15
a need to	15
of airway remodeling	15
clinical features of	15
months to years	15
the difference in	15
as it is	15
murine model of	15
in all groups	15
been studied in	15
role of respiratory	15
air quality and	15
of the host	15
and nutrition examination	15
as a major	15
in later childhood	15
with the exception	15
the gastrointestinal tract	15
peripheral blood eosinophilia	15
individuals with asthma	15
of the association	15
total number of	15
to air pollution	15
studies showed that	15
in allergy and	15
bacteria and viruses	15
of asthma among	15
the rest of	15
were assessed by	15
in spite of	15
side effects of	15
in prevalence of	15
of asthma were	15
the first two	15
in the production	15
the sensitivity and	15
parents and children	15
located in the	15
hospital admissions for	15
after one year	15
children at risk	15
was performed using	15
institutes of health	15
in the course	15
of respiratory infections	15
respiratory illness in	15
report the case	15
the design of	15
in health and	15
and mast cells	15
immune response in	15
past medical history	15
of allergic inflammation	15
and with a	15
with nasal polyps	15
and family history	15
for food allergy	15
of viruses in	15
is an effective	15
cells from asthmatic	15
are involved in	15
out of the	15
contribute to asthma	15
of the following	15
children with high	15
at our institution	15
the exception of	15
have been proposed	15
a wide variety	15
a longitudinal study	15
health care utilization	15
the bronchial epithelium	15
are caused by	15
adverse effects of	15
is not clear	15
wheezing rhinovirus illnesses	15
upper respiratory infections	15
have suggested that	15
hospitalized patients with	15
measured using a	15
be increased in	15
a correlation between	15
with recurrent wheezing	15
rhinitis and or	15
lung function at	15
which is the	15
that there are	15
up to years	15
and atopy in	14
number of asthma	14
perennial allergic rhinitis	14
written asthma action	14
in asthma control	14
only a few	14
patients with bronchiectasis	14
the usefulness of	14
and lower airway	14
airway obstruction and	14
in the use	14
symptoms and asthma	14
on the use	14
is found in	14
safety and tolerability	14
life predict asthma	14
skin test to	14
short course of	14
children with cystic	14
was not significant	14
at and years	14
likely due to	14
with other respiratory	14
account for the	14
inflammatory cells in	14
pulmonary disease and	14
for asthma exacerbation	14
exacerbation in children	14
and cytokine production	14
who had been	14
the need to	14
idiopathic eosinophilic myositis	14
chronic airway inflammation	14
should be avoided	14
between the ages	14
year old male	14
swelling of the	14
ara h and	14
participate in the	14
and an increase	14
had not been	14
treatment should be	14
of up to	14
ethnic differences in	14
children less than	14
not been previously	14
of those with	14
wheeze and asthma	14
of airway remodelling	14
that the risk	14
asthma and respiratory	14
and heart rate	14
of tumstatin in	14
we investigated the	14
of asthma severity	14
of respiratory viral	14
and the number	14
of the drug	14
are required to	14
are based on	14
model of asthma	14
prick tests were	14
the nature of	14
epithelial cells are	14
with an acute	14
a control group	14
in both cases	14
disease characterized by	14
s per person	14
the major cause	14
as assessed by	14
asthma is characterized	14
associated with acute	14
of chronic urticaria	14
of early childhood	14
with control subjects	14
no differences in	14
to explore the	14
based on clinical	14
treatment of severe	14
lung volumes and	14
in one second	14
positive response to	14
in elderly patients	14
used to compare	14
neutrophil extracellular traps	14
detection of respiratory	14
with an increasing	14
onset of symptoms	14
colonization of the	14
fruits and vegetables	14
of wheeze and	14
diagnosis of copd	14
a link between	14
in any patient	14
in the emergency	14
in nasal lavage	14
in a number	14
play a key	14
the median age	14
and does not	14
children with chronic	14
recurrent wheezing in	14
l s per	14
studies of the	14
of inhaled steroids	14
in asthma is	14
oral allergy syndrome	14
allergic contact dermatitis	14
than those without	14
the complexity of	14
for those with	14
an effect on	14
can be identified	14
on the respiratory	14
to establish the	14
and had a	14
patients with respiratory	14
comparable to that	14
of asthma medication	14
to an increased	14
cells such as	14
activity of the	14
total and specific	14
patients with cf	14
is often used	14
more severe asthma	14
in infancy is	14
to the study	14
longitudinal cohort study	14
episodes of wheezing	14
a single dose	14
of innate immunity	14
of pulmonary function	14
in children is	14
on asthma and	14
of the chest	14
c motif chemokine	14
approved by the	14
the diagnosis is	14
to account for	14
is unlikely to	14
of people with	14
reversible airway obstruction	14
initiation of asthma	14
aspects of the	14
to predict the	14
results a total	14
horses with mild	14
mutations in the	14
this pilot study	14
des asthma bronchiale	14
total of children	14
the airway and	14
they are not	14
csf and il	14
loss of lung	14
as a potential	14
on quality of	14
and symptoms of	14
with a median	14
is not possible	14
eosinophilic inflammation and	14
nutrition examination survey	14
a significant correlation	14
tests were performed	14
a cause of	14
fall in fev	14
the lung microbiome	14
volume in one	14
between viral infection	14
role of viruses	14
important risk factor	14
among children in	14
high doses of	14
chronic otitis media	14
asthma compared with	14
a written asthma	14
asthma patients and	14
is that the	14
the loss of	14
disease and asthma	14
between exposure to	14
to be less	14
the reasons for	14
and control groups	14
shown to induce	14
to use a	14
and in vitro	14
is a key	14
poorly controlled asthma	14
a randomized trial	14
in patients and	14
in up to	14
up to the	14
of these findings	14
admitted to the	14
approach to the	14
resolution of the	14
as many as	14
resulting in a	14
in asthmatic and	14
the start of	14
health effects of	14
with severe or	14
not yet been	14
to age years	14
in idiopathic pulmonary	14
significant correlation between	14
this article is	14
by t cells	14
has been linked	14
dendritic cells and	14
within minutes of	14
was seen in	14
was found between	14
persons with asthma	14
data will be	14
of a year	14
to the use	14
prick test with	14
skin tests and	14
with exposure to	14
patients with non	14
with a low	14
provided by the	14
it was shown	14
and there was	14
exposure to high	14
of the skin	14
with a reduction	14
blood eosinophil count	14
allergic rhinitis patients	14
mast cell activation	14
have been used	14
cells of the	14
to describe the	14
to inhaled corticosteroids	14
in one patient	14
in the allergic	14
acute asthma attacks	14
risk of respiratory	14
known about the	14