quadgram

This is a table of type quadgram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

quadgram	frequency
chronic obstructive pulmonary disease	168
of this study was	131
this study was to	128
the development of asthma	119
the aim of this	118
in the united states	111
aim of this study	105
in the treatment of	102
has been shown to	92
with a history of	84
been shown to be	80
in the development of	79
in children with asthma	79
for the treatment of	77
first year of life	77
in patients with asthma	77
have been shown to	71
the first year of	71
in the pathogenesis of	70
a risk factor for	64
the risk of asthma	63
has been associated with	61
in the first year	56
asthma in the elderly	56
at the time of	55
in the presence of	55
is one of the	55
at years of age	54
an important role in	52
first years of life	52
to be associated with	52
of asthma in the	52
the first years of	51
the prevalence of asthma	51
play a role in	50
there was a significant	50
studies have shown that	49
exacerbations of asthma in	49
the age of years	48
and the development of	48
in the absence of	48
were more likely to	48
one of the most	48
on the other hand	47
patients with severe asthma	45
to the development of	45
is the most common	45
increase the risk of	44
in patients with severe	44
an increased risk of	43
to years of age	43
associated with an increased	43
more likely to have	43
as well as the	42
for the development of	42
in the management of	42
systematic review and meta	41
of asthma in children	40
these data suggest that	40
asthma exacerbations in children	40
there was no significant	40
it is important to	40
at the age of	39
respiratory syncytial virus infection	39
was found to be	38
in the prevalence of	38
as a result of	38
risk factor for asthma	38
the natural history of	37
of patients with asthma	37
have been associated with	37
a systematic review and	36
our aim was to	36
diagnosis and management of	35
in children and adults	35
were found to be	35
da asma j pinto	35
on the basis of	35
asma j pinto mendes	35
with a diagnosis of	34
cells from donors with	34
respiratory syncytial virus bronchiolitis	34
of asthma exacerbations in	34
forced expiratory volume in	34
play an important role	34
of viral infections in	33
in patients with chronic	33
is thought to be	33
in the airways of	33
in the control group	33
a significant increase in	33
can be used to	33
there were no significant	32
of respiratory syncytial virus	32
of chronic obstructive pulmonary	32
in the setting of	32
the objective of this	31
in the context of	31
in addition to the	31
role of viral infections	31
more likely to be	31
this is the first	30
of children with asthma	30
report a case of	30
is associated with a	30
it has been shown	29
at the same time	29
patients with asthma and	29
studies are needed to	29
of the airway epithelium	29
acute exacerbations of asthma	29
with and without asthma	29
may be associated with	29
patients with a history	28
a role in the	28
asm cells from donors	28
lower respiratory tract infections	28
with chronic obstructive pulmonary	28
the treatment of asthma	28
study was to evaluate	28
natural history of asthma	28
the pathogenesis of asthma	28
may be due to	28
there was no difference	28
were included in the	28
we report a case	28
are more likely to	28
in the first years	28
global initiative for asthma	28
of exhaled nitric oxide	28
the development of allergic	27
with the development of	27
was to evaluate the	27
in adults and children	27
with an increased risk	27
peripheral blood mononuclear cells	27
in exacerbations of asthma	27
the lower respiratory tract	27
no significant difference in	27
was associated with an	26
risk factors for asthma	26
respiratory tract infections in	26
at the end of	26
and quality of life	26
of asthma and allergic	26
and management of asthma	26
risk of developing asthma	26
in adults with asthma	26
as well as a	25
efficacy and safety of	25
asthma and allergic rhinitis	25
in the case of	25
in the diagnosis of	25
is associated with increased	25
of asthma and allergies	25
in early life and	25
the role of the	25
in a mouse model	25
study was to assess	25
patients with allergic rhinitis	25
the case of a	25
for the diagnosis of	25
the diagnosis and management	25
upper respiratory tract infections	25
increased risk of asthma	24
in airway epithelial cells	24
in a cohort of	24
development of asthma and	24
risk of childhood asthma	24
was no significant difference	24
a family history of	24
the incidence of asthma	24
included in the study	24
as a risk factor	24
prevalence of asthma and	24
reduce the risk of	24
fractional exhaled nitric oxide	23
family history of atopy	23
the end of the	23
this study aimed to	23
presence or absence of	23
infections in exacerbations of	23
for the prevention of	23
has been reported to	23
that there is a	23
viral infections in exacerbations	23
there is a need	23
of the immune system	23
was associated with a	23
a diagnosis of asthma	23
of the most common	23
the diagnosis of asthma	23
the most common cause	23
in accordance with the	23
it is possible that	23
for the diagnosis and	23
of asthma in adults	23
had a history of	23
in the number of	23
was no difference in	22
an increase in the	22
community study of role	22
with increased risk of	22
the purpose of this	22
of eosinophils in the	22
as well as in	22
otitis media with effusion	22
department of health and	22
of a number of	22
study of role of	22
was not associated with	22
upper respiratory tract infection	22
in this age group	22
these results suggest that	22
was significantly associated with	22
the aim of the	22
of role of viral	22
a total of patients	22
associated with the development	22
diagnosis and treatment of	22
in the placebo group	22
were significantly higher in	21
respiratory tract infection in	21
in patients with copd	21
associated with increased risk	21
a wide range of	21
most common cause of	21
is a risk factor	21
at months of age	21
years of age and	21
a randomized controlled trial	21
in the last months	21
the management of asthma	21
development of asthma in	21
the use of a	21
associated with asthma exacerbations	21
has been shown that	21
allergic rhinitis and asthma	21
was to determine the	20
and the risk of	20
and risk of asthma	20
the majority of the	20
a mouse model of	20
a mean age of	20
respiratory syncytial virus in	20
increases the risk of	20
asthma and allergies in	20
little is known about	20
granzyme b expression in	20
the immune response to	20
was to assess the	20
the effect of tezepelumab	20
asthma and allergic disease	20
in chronic obstructive pulmonary	20
of asthma and allergy	20
first months of life	20
on the development of	20
a better understanding of	20
prevention and treatment of	20
has been found to	20
quality of life questionnaire	20
in the last year	20
is likely to be	20
the forced oscillation technique	20
infants and young children	20
during the first years	20
children aged to years	20
the mean age of	20
in the form of	20
in the general population	19
no significant differences in	19
objective of this study	19
been found to be	19
in the majority of	19
study was to determine	19
was the most common	19
in the group of	19
with a mean age	19
for the management of	19
is associated with the	19
syncytial virus bronchiolitis in	19
and exacerbations of asthma	19
the use of the	19
with an increase in	19
the severity of asthma	19
acute respiratory distress syndrome	19
with allergic rhinitis and	19
higher in patients with	19
been reported to be	19
with respiratory syncytial virus	19
a systematic review of	19
compared with the control	19
decline in lung function	19
viral respiratory tract infections	19
improvement in lung function	19
in patients with allergic	19
and chronic obstructive pulmonary	19
also been shown to	19
syncytial virus infection in	19
the first months of	19
severe respiratory syncytial virus	18
and lower respiratory tract	18
the presence or absence	18
in a group of	18
vitro and in vivo	18
in the previous months	18
children younger than years	18
than years of age	18
associated with asthma exacerbation	18
role in the development	18
a positive correlation between	18
a higher risk of	18
in the united kingdom	18
purpose of this study	18
and severity of asthma	18
morbidity and mortality in	18
a significant role in	18
of the patients had	18
risk of asthma exacerbations	18
there were no differences	18
related quality of life	18
of morbidity and mortality	18
the presence of eosinophils	18
virus bronchiolitis in infancy	18
in vitro and in	18
be a risk factor	18
of interstitial lung disease	17
risk of asthma in	17
upper and lower respiratory	17
and respiratory syncytial virus	17
quality of life and	17
j allergy clin immunol	17
children with acute asthma	17
has been identified as	17
in children younger than	17
in the immune response	17
children with asthma exacerbation	17
in a study of	17
aim of the study	17
global strategy for asthma	17
with mild to moderate	17
has been suggested that	17
it is likely that	17
national health and nutrition	17
asthma quality of life	17
may contribute to the	17
history of asthma and	17
was associated with increased	17
for the first time	17
it is clear that	17
our understanding of the	17
and is associated with	17
is known to be	17
may play a role	17
were measured by elisa	17
of bronchial epithelial cells	17
significant difference in the	17
to the emergency department	17
contribute to the development	17
of patients with chronic	17
was to investigate the	17
of respiratory viruses in	17
international study of asthma	17
study of asthma and	17
had no effect on	17
there was an increase	17
should be considered in	17
to the control group	17
with respiratory tract infection	17
in a recent study	17
the presence of a	17
the mean age was	17
in children with acute	17
have been implicated in	17
the course of the	17
have been reported in	17
the upper respiratory tract	17
strategy for asthma management	17
and the use of	16
pregnant women with asthma	16
the prevalence of allergic	16
lower respiratory tract infection	16
was to examine the	16
in patients with mild	16
it is unknown whether	16
from donors with and	16
with the control group	16
a significant reduction in	16
in any of the	16
and allergies in childhood	16
aged years and over	16
patients with asthma or	16
of this study is	16
of house dust mite	16
t cells and monocytes	16
in a range of	16
between the two groups	16
test was used to	16
to be effective in	16
been associated with asthma	16
in bronchial epithelial cells	16
b expression in blood	16
we present a case	16
was an increase in	16
was supported by the	16
as part of a	16
associated with an increase	16
the number of patients	16
genetic and environmental factors	16
further studies are needed	16
research is needed to	16
important role in the	16
of the patients were	16
of lung function in	16
guidelines for the diagnosis	16
asthma management and prevention	16
of allergic rhinitis and	16
donors with and without	16
the diagnosis and treatment	16
present a case of	16
asthma and chronic obstructive	16
by asm cells from	16
investigate the effect of	16
it has been suggested	16
had at least one	16
for asthma management and	16
in patients with a	16
have shown that the	16
to house dust mite	16
in this study we	16
the role of eosinophils	16
studies have demonstrated that	16
report the case of	15
shown to be effective	15
a large number of	15
and years of age	15
diseases such as asthma	15
the results of the	15
health and nutrition examination	15
compared to the control	15
of the study was	15
a wide variety of	15
study was to investigate	15
human airway epithelial cells	15
mild to moderate asthma	15
quality of life in	15
and allergy at age	15
associated with asthma and	15
in the bone marrow	15
a key role in	15
to investigate the effect	15
found to be associated	15
with the exception of	15
a birth cohort study	15
in the treatment group	15
has been reported in	15
continuous positive airway pressure	15
asthma and allergy at	15
the development of the	15
in the production of	15
the majority of patients	15
and specific ige to	15
role of eosinophils in	15
were years of age	15
development of childhood asthma	15
in the course of	15
been identified as a	15
may be involved in	15
to be the most	15
during the first year	15
have been found to	15
are associated with the	15
asthma is a chronic	15
been shown to have	15
may be related to	15
the severity of the	15
the treatment of allergic	15
management of asthma in	15
with moderate to severe	15
better understanding of the	15
we report the case	15
family history of asthma	15
were no significant differences	15
associated with respiratory tract	15
was shown to be	15
of asthma in childhood	15
in health and disease	15
likely to have a	15
a retrospective chart review	15
elderly patients with asthma	15
asthma and allergic diseases	15
wheezing rhinovirus illnesses in	15
the patient had a	15
levels were significantly higher	14
incidence of asthma and	14
a higher prevalence of	14
of the hygiene hypothesis	14
in infants and young	14
the world health organization	14
expiratory volume in one	14
volume in one second	14
in a number of	14
the onset of asthma	14
between viral infection and	14
a high prevalence of	14
results a total of	14
with seasonal allergic rhinitis	14
is associated with asthma	14
in children with a	14
asthma is characterized by	14
and an increase in	14
children with cystic fibrosis	14
was not significantly different	14
severe asthma with fungal	14
in the past months	14
are likely to be	14
was used to assess	14
a total of children	14
are thought to be	14
at high risk for	14
in people with asthma	14
safety and efficacy of	14
were observed in the	14
role in the pathogenesis	14
and nutrition examination survey	14
between the ages of	14
to high levels of	14
a prospective study of	14
in young children with	14
included in this study	14
and lung function in	14
and a decrease in	14
national institutes of health	14
of the respiratory system	14
the airways of asthmatics	14
this study is to	14
the risk of developing	14
patients with copd and	14
has also been shown	14
the major cause of	14
l s per person	14
exhaled nitric oxide in	14
review of the literature	14
will be used to	14
in the pediatric population	14
a case of a	14
patients with chronic obstructive	14
in children and adolescents	14
play a key role	14
was a significant difference	14
the study was to	14
lower respiratory tract symptoms	14
change from baseline in	14
associated with a higher	14
an acute asthma exacerbation	14
at increased risk of	14
and family history of	13
a high level of	13
against the development of	13
a prospective cohort study	13
early life predict asthma	13
of severe asthma in	13
treatment of acute asthma	13
house dust mite allergen	13
of airway smooth muscle	13
of asthma control medication	13
the ability of the	13
in the use of	13
on the use of	13
as risk factors for	13
children with asthma and	13
of allergy and asthma	13
a written asthma action	13
aim to determine the	13
at the beginning of	13
in idiopathic pulmonary fibrosis	13
years of age with	13
to be increased in	13
important risk factor for	13
the efficacy and safety	13
asthma exacerbation in children	13
also play a role	13
cytokines such as il	13
no difference in the	13
is needed to determine	13
case of a year	13
effect of tezepelumab on	13
analysis was used to	13
life predict asthma development	13
treatment of allergic rhinitis	13
severe acute respiratory syndrome	13
with the diagnosis of	13
in allergy and asthma	13
retrospective chart review of	13
children with a history	13
the frequency of asthma	13
in balb c mice	13
to confirm these findings	13
innate and adaptive immune	13
to a variety of	13
asthma with fungal sensitization	13
is known about the	13
seems to be a	13
illnesses in early life	13
obstructive pulmonary disease and	13
fold increase in il	13
percentage change in fev	13
to play a role	13
of patients with a	13
to be a useful	13
the development of childhood	13
to the use of	13
and the number of	13
on the severity of	13
the treatment of acute	13
rhinovirus illnesses in early	13
written asthma action plan	13
at high risk of	13
study was to examine	13
to the age of	13
this may be due	13
development of allergic disease	13
to complete a questionnaire	13
we hypothesized that the	13
was significantly higher in	13
was observed in the	13
upper and lower airway	13
infections in children with	13
life and risk of	13
there is a high	13
who did not have	13
acute exacerbation of asthma	13
appears to be a	13
has been linked to	13
acute respiratory tract infections	13
predict asthma development in	13
has been implicated in	13
of patients with severe	13
after one year of	13
and asthma in children	13
as part of the	13
on the role of	13
in early life predict	13
examined the effect of	13
been diagnosed with asthma	13
these findings suggest that	12
has led to the	12
the development of a	12
clinically significant improvement in	12
a higher incidence of	12
influenza a h n	12
a small number of	12
mice exposed to cig	12
informed consent was obtained	12
crc for asthma and	12
it was shown that	12
exposed to cig smoke	12
in the regulation of	12
of the effect of	12
respiratory syncytial virus and	12
lung cancer cell lines	12
viruses and exacerbations of	12
asthma is associated with	12
primeiros anos de vida	12
respiratory viruses and exacerbations	12
both children and adults	12
asthma and asthma exacerbations	12
be due to the	12
of this analysis was	12
role for eosinophils in	12
a single dose of	12
randomized controlled trial of	12
in a variety of	12
in copd and bronchiectasis	12
of health and ageing	12
it is difficult to	12
been associated with increased	12
peking university first hospital	12
an important risk factor	12
by respiratory syncytial virus	12
a randomised controlled trial	12
increase in the prevalence	12
of thymic stromal lymphopoietin	12
airway inflammation in asthma	12
moderate to severe asthma	12
for at least months	12
there was a high	12
is a need to	12
prevalence of allergic diseases	12
in a murine model	12
has been hypothesized that	12
of sensitization to cat	12
specific ige and igg	12
by t cells and	12
on the effect of	12
the high fat meal	12
apoptosis of bronchial epithelial	12
primary prevention of asthma	12
t reg cd cd	12
with a reduction in	12
and its impact on	12
there is evidence that	12
in the nasal mucosa	12
and granzyme b expression	12
before and after bd	12
asthma in older adults	12
with lower respiratory tract	12
under years of age	12
sensitivity and specificity of	12
the rest of the	12
between alexithymia and asthma	12
on quality of life	12
the most common chronic	12
initiation of asthma control	12
in more than of	12
evaluation and management of	12
are the major cause	12
exhaled nitric oxide and	12
were included in this	12
been shown to induce	12
with advanced lung disease	12
prevalence of asthma in	12
it has been hypothesized	12
for asthma and airways	12
there was no correlation	12
of the role of	12
innate immune response to	12
to determine the prevalence	12
in acute asthma exacerbations	12
of this study were	12
objective of this analysis	12
the sensitivity and specificity	12
in contrast to the	12
in the cbt group	12
the american thoracic society	12
bronchial epithelial cells and	12
obstructive sleep apnea syndrome	12
with the use of	12
the exacerbation of asthma	12
treatment of asthma in	12
supported by the nhmrc	12
by the presence of	12
horses with severe ea	12
to house dust mites	12
is not associated with	12
this analysis was to	12
a decrease in the	12
of the disease and	12
an increase in airway	12
vascular endothelial growth factor	12
asthma development in high	12
asthma in the previous	12
reg cd cd high	12
and the severity of	12
in the exercise group	12
that the risk of	12
over years of age	12
on the management of	12
there has been a	12
study was to compare	12
also been associated with	12
fraction of exhaled nitric	12
is increased in asthma	12
been associated with the	11
of the immune response	11
the proportion of patients	11
is a need for	11
have the potential to	11
a result of the	11
with severe persistent asthma	11
were excluded due to	11
were higher in patients	11
the grass pollen season	11
the results showed that	11
the time of the	11
the total number of	11
to the presence of	11
treatment of severe asthma	11
peak expiratory flow rate	11
of allergic diseases in	11
of viral respiratory infections	11
it has been demonstrated	11
children and adults with	11
the expression of the	11
of asthma has been	11
a year old woman	11
of infections in the	11
it was found that	11
for the use of	11
skin prick tests with	11
an acute exacerbation of	11
the authors concluded that	11
ara h and ara	11
of respiratory pathogens in	11
was to estimate the	11
was obtained from the	11
to be involved in	11
in lung function in	11
regression was used to	11
in the upper respiratory	11
the effect of a	11
total and specific ige	11
to the risk of	11
determine the prevalence of	11
in patients with bronchiectasis	11
of asthma and other	11
a significant correlation between	11
a significant decrease in	11
was significantly higher than	11
mean age of the	11
the differential diagnosis of	11
been shown to reduce	11
plays a role in	11
a positive skin prick	11
and there is a	11
the sensitivity of the	11
is an important risk	11
asthma education and prevention	11
be used as a	11
with asthma or copd	11
was a significant increase	11
the potential role of	11
tract infections in children	11
with idiopathic pulmonary fibrosis	11
been implicated in the	11
a review of the	11
independent risk factor for	11
of atopy and asthma	11
national asthma education and	11
asthma in children and	11
bronchiolitis in infancy is	11
positive skin prick test	11
in infancy is an	11
in infants and children	11
divided into two groups	11
that the use of	11
in which a single	11
at least in part	11
was to compare the	11
be one of the	11
a murine model of	11
when compared to the	11
of the children with	11
length of hospital stay	11
the prevalence of childhood	11
more than half of	11
the mrna expression of	11
the ecp g c	11
the size of the	11
infancy predict subsequent childhood	11
that the prevalence of	11
for the adult and	11
time to initiation of	11
are one of the	11
in both children and	11
during the course of	11
the vast majority of	11
patients with mild to	11
allergic airway inflammation in	11
chronic otitis media with	11
predict subsequent childhood wheezing	11
in the present study	11
infancy is an important	11
of inhaled corticosteroids in	11
human bronchial epithelial cells	11
the number of cd	11
in patients with moderate	11
and then infected with	11
and increased risk of	11
risk of asthma and	11
in pregnant women with	11
during infancy predict subsequent	11
a significant difference in	11
changes in lung function	11
h and ara h	11
up to the age	11
determine the effects of	11
despite the fact that	11
before and after the	11
ever been diagnosed with	11
were the most common	11
this has not been	11
were used to determine	11
asthma at age years	11
play a significant role	11
been associated with a	11
has been used in	11
are associated with an	11
the upper and lower	11
it is estimated that	11
have been found in	11
the innate immune response	11
to initiation of asthma	10
in adult patients with	10
the gold standard for	10
asma e da atopia	10
bronchial epithelial cells have	10
in children with severe	10
as well as to	10
prevalence of current asthma	10
the september epidemic of	10
parental history of asthma	10
ethnic differences in lung	10
to determine the impact	10
a year old male	10
in the first months	10
most likely to be	10
is associated with an	10
allergic rhinitis and or	10
p and der p	10
in the bronchial mucosa	10
airway smooth muscle mass	10
we examined the effect	10
with at least one	10
in relation to the	10
is associated with airway	10
of the patients who	10
impact of allergic rhinitis	10
infants at high risk	10
management of patients with	10
found in patients with	10
loss of lung function	10
we were able to	10
can be explained by	10
there are no studies	10
of upper respiratory tract	10
airway epithelial cells and	10
asthmatic bronchial epithelial cells	10
and to determine the	10
significantly higher than the	10
rhinitis and or asthma	10
their quality of life	10
the quality of life	10
the time of an	10
were no differences between	10
risk of lung cancer	10
and the occurrence of	10
was referred to our	10
response to infection with	10
on lung function and	10
education and prevention program	10
diagnosed with asthma and	10
patients with bronchial asthma	10
children to years of	10
exposure to high levels	10
have been linked to	10
patients with severe or	10
history of asthma in	10
asthma and other allergic	10
associated with more severe	10
increased risk of developing	10
in lung function and	10
the time to initiation	10
diagnosis of asthma in	10
sick building syndrome in	10
for disease control and	10
the area under the	10
vivo and in vitro	10
the role of viral	10
asthma exacerbations in the	10
to confirm the diagnosis	10
response to viral infection	10
was found to have	10
of sleep disordered breathing	10
da asma e da	10
appears to be the	10
it is possible to	10
der p and der	10
the asthma control questionnaire	10
did not differ between	10
more research is needed	10
it is thought that	10
to be a risk	10
the role of viruses	10
the immune system and	10
children with severe asthma	10
primeiros tempos de vida	10
children under years of	10
of people with asthma	10
to be responsible for	10
skin prick tests and	10
two years of age	10
high resolution computed tomography	10
during the grass pollen	10
levels in patients with	10
increased airway smooth muscle	10
were randomized to receive	10
is considered to be	10
children were randomized into	10
of the general population	10
and other allergic diseases	10
patients with chronic respiratory	10
cells were exposed to	10
confirmed the presence of	10
symptoms in the last	10
disease control and prevention	10
to participate in the	10
the first two years	10
have a role in	10
prevalence of childhood asthma	10
a positive skin test	10
association between exposure to	10
the ages of and	10
safety and tolerability of	10
lower limit of normal	10
factor for asthma and	10
likely to play a	10
to the fact that	10
due to lack of	10
the beginning of the	10
has been observed in	10
our study was to	10
in a patient with	10
european community respiratory health	10
associated with asthma hospitalizations	10
infections in the development	10
that asthma is a	10
patients with asthma are	10
september epidemic of asthma	10
between and years of	10
and in the absence	10
group of patients with	10
the production of il	10
study was undertaken to	10
may also play a	10
analyses were performed using	10
institute of medical research	10
young children with respiratory	10
of our study was	10
data suggest that the	10
there is a significant	10
the international study of	10
of asthma and copd	10
are the most common	10
the pathophysiology of asthma	10
primary outcome was the	10
is funded by the	10
logistic regression was used	10
was defined as a	10
those who did not	10
there appears to be	10
epithelial cells have a	10
was to study the	10
that patients with asthma	10
and was associated with	10
in vivo and in	10
than those with a	10
exacerbation of asthma in	10
the subsequent development of	10
our data suggest that	10
significantly higher in the	10
to infection with rhinovirus	10
asthma and respiratory symptoms	10
those reported in the	10
the evaluation and management	10
children less than years	10
nos primeiros tempos de	10
woolcock institute of medical	10
is a feature of	10
with other respiratory viruses	10
on the prevalence of	10
assess the effect of	10
of patients with allergic	10
differences in lung function	10
were not associated with	10
prevention of asthma and	10
have a deficient innate	9
holder for this preprint	9
was more common in	9
a crucial role in	9
statistical analyses were performed	9
institute of health and	9
was higher in the	9
are related to the	9
medrxiv a license to	9
influenza a and b	9
for recruitment to the	9
up to years of	9
a short course of	9
were performed using spss	9
of the respiratory tract	9
role of deficient type	9
was undertaken to determine	9
and wheezing in the	9
of childhood asthma is	9
wheezing in young children	9
he was treated with	9
increased risk of childhood	9
in order to prevent	9
children ages to years	9
in the prevention of	9
asthma is the most	9
considered to be a	9
implicated in the pathogenesis	9
respiratory symptoms in the	9
and exacerbation of asthma	9
copyright holder for this	9
asthma at years of	9
such as asthma and	9
and risk of wheeze	9
were detected in of	9
reported to be increased	9
the rescue intervention strategy	9
expiratory volume in second	9
with an acute asthma	9
the symptoms of asthma	9
in the absence or	9
cause of asthma exacerbations	9
role of viruses in	9
epidermal growth factor receptor	9
asthma and wheezing in	9
wheezing in the first	9
of asthma in older	9
old female with a	9
were significantly associated with	9
the study of the	9
mast cells and basophils	9
children to years old	9
during the study period	9
in human airway epithelial	9
for the majority of	9
virus in early life	9
than that of the	9
asthma symptoms and asthma	9
of airway inflammation in	9
guidelines for the management	9
health and human services	9
license to display the	9
respiratory viral infections are	9
to assess the efficacy	9
small number of patients	9
in the field and	9
asthma is related to	9
to a lesser extent	9
of asthma in pregnancy	9
and natural history of	9
levels were higher in	9
and the need for	9
viruses were detected in	9
in asthmatic and non	9
is yet to be	9
in a model of	9
exacerbations in children and	9
children with high rhinovirus	9
plays an important role	9
upper or lower respiratory	9
was significantly increased in	9
more studies are needed	9
exacerbations of chronic obstructive	9
is the author funder	9
is responsible for the	9
an increased risk for	9
in airway smooth muscle	9
with the severity of	9
was associated with higher	9
of wheeze and allergy	9
cells have a deficient	9
are consistent with the	9
we have previously reported	9
risk of asthma development	9
of acute asthma exacerbations	9
induced exacerbations of asthma	9
in subjects with asthma	9
examine the effect of	9
objectives of this study	9
in terms of the	9
from birth to years	9
is related to the	9
suggest that there is	9
of the use of	9
regression analysis was used	9
who has granted medrxiv	9
we did not observe	9
to assess changes in	9
infections are associated with	9
australian institute of health	9
found to have a	9
of rhinovirus infections in	9
to evaluate the effect	9
of asthma and atopy	9
prior to the procedure	9
a license to display	9
display the preprint in	9
was associated with the	9
infections in the first	9
granted medrxiv a license	9
the airway smooth muscle	9
in the pathophysiology of	9
and asthma and allergy	9
centers for disease control	9
community respiratory health survey	9
of symptoms of asthma	9
to examine the effect	9
this study were to	9
age of the patients	9
subjects with chronic obstructive	9
high rhinovirus genome load	9
are associated with asthma	9
year of life and	9
this version posted july	9
development of persistent asthma	9
investigate the relationship between	9
no change in il	9
may be important in	9
the impact of allergic	9
of acute asthma in	9
the preprint in perpetuity	9
she was treated with	9
the innate immune system	9
of acid reflux disorders	9
prevalence of sbs symptoms	9
of airway epithelial cells	9
patients with mild asthma	9
is to evaluate the	9
in up to of	9
illnesses during infancy predict	9
had a family history	9
the mechanisms by which	9
be associated with the	9
a birth cohort of	9
over the last years	9
of health and human	9
early life exposure to	9
of randomized controlled trials	9
thought to be a	9
studies have focused on	9
participated in this study	9
for this preprint this	9
two years of life	9
for asthma in the	9
early life and risk	9
be associated with a	9
prevalence of asthma was	9
to display the preprint	9
in the lungs of	9
the innate and adaptive	9
before and after treatment	9
of allergic sensitization and	9
under the age of	9
of deficient type iii	9
viral respiratory tract infection	9
a high incidence of	9
us department of health	9
production in asthma exacerbations	9
during the first months	9
preprint this version posted	9
a higher rate of	9
in patients with the	9
a history of recurrent	9
by the age of	9
daily peak expiratory flow	9
the functional significance of	9
the role of alternative	9
response to rv infection	9
with the presence of	9
wheeze and allergy by	9
rhinovirus illnesses during infancy	9
risk of wheeze and	9
respiratory viral infections in	9
cohort of infants with	9
that the number of	9
the increased prevalence of	9
is based on the	9
be higher in the	9
practitioners in the field	9
the united states and	9
in patients with pneumonia	9
and allergy by age	9
study was conducted in	9
the department of health	9
an atopic family history	9
months prior to the	9
were divided into groups	9
a retrospective study of	9
aim was to determine	9
were found to have	9
the development of pulmonary	9
infection and allergen exposure	9
the mechanism by which	9
alone or in combination	9
as a cause of	9
stable subjects with asthma	9
pathogenesis has not been	9
prick tests were positive	9
ige and igg levels	9
children at high risk	9
with an improvement in	9
years of age were	9
effects of air pollution	9
number of patients with	9
the copyright holder for	9
was no correlation between	9
important role in asthma	9
the airway epithelium in	9
and response to treatment	9
gamma ifn and il	9
the national health and	9
the role of respiratory	9
severity of airflow obstruction	9
the effect of the	9
asthma and atopic dermatitis	9
development of allergic diseases	9
was associated with reduced	9
the need for a	9
patients with moderate to	9
increase in the number	9
the primary prevention of	9
of the severity of	9
has granted medrxiv a	9
to be due to	9
thought to contribute to	9
this preprint this version	9
the control of asthma	9
higher than that in	9
first two years of	9
for the assessment of	9
for patients with asthma	9
viral infections and asthma	9
be involved in the	9
and asthma exacerbations in	9
mean asm cell volume	8
and treatment of asthma	8
is protected by copyright	8
the first strategy recruited	8
predictors of a positive	8
asthma by age had	8
monocytes were separated from	8
the australian institute of	8
used in the treatment	8
from other leukocytes by	8
of asthma associated with	8
genes contribute to the	8
a doctor diagnosis of	8
the effects of port	8
was examined in lung	8
th and th cytokines	8
absence or presence of	8
by placental abruption at	8
it was suggested that	8
older people with asthma	8
factors for asthma exacerbations	8
and functionally distinct protein	8
should be considered for	8
patients with asthma were	8
length of stay was	8
used to assess associations	8
or in combination with	8
pregnancy was complicated by	8
patterns of asthma medication	8
asthma action plan was	8
in those with lung	8
which peripheral blood mononuclear	8
research was supported by	8
was analysed by flow	8
have been observed in	8
not associated with the	8
the european community respiratory	8
children at risk of	8
in asthma and related	8
was isolated and reverse	8
and frequent asthmatics had	8
support the use of	8
severity in copd patients	8
ige and specific ige	8
signs and symptoms of	8
s domain of the	8
ascertain asthma in the	8
transforming growth factor b	8
years to ascertain asthma	8
asthma at the age	8
been found to have	8
inflammation at the tumour	8
progression of the disease	8
doctor diagnosis of asthma	8
in the near future	8
between and within cell	8
significantly higher than that	8
differentiated into dendritic cells	8
but no change in	8
of appropriately sized donor	8
of asm cells is	8
single gene can generate	8
the chronic inflammatory asthma	8
of tumstatin in the	8
a single gene can	8
into dendritic cells following	8
to better understand the	8
cell ifng and tnfa	8
of severe and aspirin	8
appropriately sized donor lungs	8
systematic review and metaanalysis	8
an indirect measure of	8
at the level of	8
admitted to hospital with	8
following incubation with defined	8
of current asthma in	8
in asthma are underway	8
viruses associated with asthma	8
with both severe asthma	8
birth cohort of infants	8
of seasonal allergic rhinitis	8
were conducted at and	8
care of patients with	8
was performed in a	8
separated from other leukocytes	8
was approved by the	8
dispensed between july and	8
before the age of	8
eosinophilic infiltration of the	8
asthma from childhood to	8
with a decrease in	8
conclusion this pilot study	8
complicated by placental abruption	8
it is not known	8
maternal smoking during pregnancy	8
was measured at baseline	8
recruited gps over months	8
role of respiratory viruses	8
proposed minimum database for	8
for the common cold	8
is a collaborating unit	8
a subgroup of asthmatics	8
in patients treated with	8
the lower limit of	8
which is associated with	8
significance of our findings	8
leading cause of death	8
airway hyperresponsiveness and angiogenesis	8
from birth to age	8
in the recruitment of	8
samples were collected from	8
are known to be	8
the global lung function	8
increased the risk of	8
patients did not have	8
of the a chain	8
levels of total ige	8
of individual respiratory events	8
o concentration between the	8
was complicated by placental	8
to reduce the risk	8
at the tumour site	8
viruses as precipitants of	8
tests were used to	8
viral respiratory infections in	8
recurrent wheezing and asthma	8
becs from subjects with	8
increased release of il	8
in asthma pathogenesis has	8
predictive normal values for	8
severity of asthma exacerbation	8
found that s p	8
in the nasal aspirates	8
risk factor for the	8
size mandibular enclosure volume	8
is the first study	8
in lung cancer cells	8
who could be considered	8
after the end of	8
had ever been diagnosed	8
the patient had no	8
aspirates and sputum samples	8
method a birth cohort	8
with the international recommendations	8
a written action plan	8
with an atopic family	8
to the cbt intervention	8
to increased release of	8
severity of sleep disordered	8
cat exposure before birth	8
of asthma during pregnancy	8
production by asm cells	8
did not affect the	8
examined in lung tissue	8
expiratory volume in s	8
cell granzyme b expression	8
weight loss and skeletal	8
prevalence and characteristics of	8
mg infusion over minutes	8
for asthma and allergy	8
increased risk of severe	8
that are associated with	8
were separated from other	8
in h o concentration	8
is the first case	8
wheeze in the first	8
defined concentrations of gm	8
subgroup of asthmatics who	8
airway epithelial cells are	8
prospectively documented up to	8
at and years to	8
was also associated with	8
has been identified in	8
candidate genes contribute to	8
group compared to the	8
or chronic obstructive pulmonary	8
in infancy and asthma	8
of all patients with	8
in the respiratory tract	8
role in the immune	8
in the last years	8
were recruited from the	8
and reduced levels of	8
before birth and development	8
a collaborating unit of	8
was a strong correlation	8
methods children who had	8
the effectiveness of a	8
absence of appropriately sized	8
pneumoniae and chlamydia pneumoniae	8
by the department of	8
primary bronchial epithelial cells	8
upper and lower airways	8
who had failed bosentan	8
evaluate the effect of	8
associated with asthma in	8
of infants with an	8
and fev fvc ratio	8
structural changes in the	8
the absence or presence	8
to cig smoke had	8
respiratory viruses were detected	8
who had ever been	8
in the third trimester	8
for both practitioners in	8
could be considered for	8
migration of mature dc	8
we present the case	8
we are conducting a	8
birth to years of	8
a literature review of	8
with defined concentrations of	8
patients with asthma in	8
higher than that of	8
isolated and reverse transcribed	8
respiratory viruses associated with	8
but not in the	8
patients with chronic asthma	8
infection in children with	8
not been previously investigated	8
of cyclin d mrna	8
ifng and tnfa production	8
are at increased risk	8
the mean percentage change	8
an increased likelihood of	8
development of pulmonary fibrosis	8
high fat meal was	8
in children less than	8
accordance with the international	8
a wide spectrum of	8
used as an indirect	8
the melbourne atopic cohort	8
intensity of asthma exacerbation	8
when subjects were years	8
which commenced in when	8
associated with severe asthma	8
mc sn lysates were	8
factors and risk of	8
over the course of	8
had respiratory symptoms in	8
leukocytes by adherence method	8
this research was supported	8
to the pathogenesis of	8
of early childhood asthma	8
infants with an atopic	8
in vitro effects of	8
allergy and clinical immunology	8
ics laba combination therapy	8
the prevalence of tuberculosis	8
the composition of the	8
between morning and evening	8
immune response to viral	8
did not observe any	8
a mean cpi of	8
there is also evidence	8
children who had ever	8
to the treatment of	8
increased prevalence of asthma	8
the study was conducted	8
a safe and effective	8
concentration between the groups	8
patients with seasonal allergic	8
of patients treated with	8
inflammatory asthma phenotypes of	8
as well as with	8
is often used as	8
of assessment of tbw	8
placental abruption at weeks	8
the field and for	8
both practitioners in the	8
prevalence of allergic rhinitis	8
in children hospitalized with	8
and airway inflammation in	8
the fact that the	8
laba combination therapy in	8
the first wheezing episode	8
important to note that	8
and establish the functional	8
the use of ics	8
patients with cystic fibrosis	8
chronic inflammation at the	8
acam is a collaborating	8
may be used to	8
mycoplasma pneumoniae and chlamydia	8
respiratory viral infections and	8
as an associated cause	8
to determine the feasibility	8
seems to be the	8
participate in the study	8
loss and skeletal muscle	8
of cytokines and chemokines	8
had received at least	8
a major cause of	8
in exhaled breath condensate	8
can generate structurally and	8
measured at baseline and	8
interviews were conducted at	8
were similar to those	8
located on chromosome q	8
and shortness of breath	8
consent was obtained from	8
of the innate immune	8
patients with and without	8
of allergic disease and	8
results there was a	8
the hypothesis that early	8
cyclin d expression in	8
evaluated the effect of	8
in patients with acute	8
the global initiative for	8
were found in the	8
conducted at and years	8
combination therapy in a	8
hypothesized that specific alternatively	8
tool in patients with	8
as an indirect measure	8
conclusion our data suggest	8
nos primeiros anos de	8
be considered as a	8
funded by the department	8
incubation with defined concentrations	8
of lower respiratory tract	8
treatment of patients with	8
reproductive factors and risk	8
children with advanced lung	8
when compared to placebo	8
in the percentage of	8
asthmatic subjects provided ml	8
cells following incubation with	8
with ahi events hour	8
of asthma at years	8
to months of age	8
this article is protected	8
positive correlation between the	8
major contributor to protein	8
the administration of antenatal	8
an mdi and spacer	8
after weeks of treatment	8
findings in asthma are	8
had a mean cpi	8
in the expression of	8
may prove to be	8
be associated with asthma	8
mechanism of action of	8
prove to be a	8
we found that s	8
had failed bosentan therapy	8
a prospective observational study	8
in children with tof	8
play a crucial role	8
associations between alternative splicing	8
pulmonary blood flow during	8
associated cause of death	8
difference between the groups	8
has been described in	8
of a positive tbb	8
a longer duration of	8
the s domain of	8
patients with chronic urticaria	8
nasal aspirates and sputum	8
there are few studies	8
mc sn and lysates	8
alternative splicing in asthma	8
bronchiolitis in infancy and	8
comorbidity associated with asthma	8
phenotypes of severe and	8
collaborating unit of the	8
in quality of life	8
the start of the	8
meeting with parents and	8
as a target for	8
last year were identified	8
and a history of	8
in a single inhaler	8
expression was assessed by	8
is the cause of	8
of asthma exacerbations and	8
to assess associations between	8
a significant association between	8
having only primary education	8
patients with asthma have	8
other leukocytes by adherence	8
even in the absence	8
and increase risk of	8
promoting chronic inflammation at	8
used to compare the	8
our findings in asthma	8
granzyme b and granulysin	8
a principal diagnosis of	8
mast cells in the	8
lack of response to	8
asthma candidate gene in	8
as well as other	8
isolated by pcr analysis	8
complementary and alternative medicine	8
induced asthma exacerbations in	8
the patient was treated	8
of asthma symptoms and	8
between alternative splicing and	8
cells and monocytes play	8
correlations between granzyme b	8
phagocytic ability of am	8
quantitative pcr and densitometry	8
history was significant for	8
exhaled nitric oxide levels	8
with a principal diagnosis	8
compared to those with	8
by years of age	8
participants in the cbt	8
family history was recruited	8
is a longitudinal population	8
in patients with persistent	8
using multiparameter flow cytometry	8
recruitment to the adf	8
an associated cause of	8
a major contributor to	8
the patient is a	8
were measured using a	8
in patients with seasonal	8
principal diagnosis of asthma	8
exposure before birth and	8
of our findings in	8
the number of eosinophils	8
caval shunt was created	8
and the prevalence of	8
is commonly used in	8
thought to be involved	8
in the previous year	8
the most commonly used	8
melbourne atopic cohort study	8
chi squared test was	8
respiratory and sleep medicine	8
of mast cells and	8
increasing the risk of	8
in total aqol scores	8
atopic family history was	8
support acam is a	8
of viral infection in	8
alternatively spliced asthma candidate	8
is important to note	8
of an asthma exacerbation	8
found to be increased	8
the absence of appropriately	8
contributor to protein diversity	8
and had respiratory symptoms	8
generate structurally and functionally	8
participants in total aqol	8
article is protected by	8
is a major contributor	8
bronchial epithelial cell apoptosis	8
mean percentage change in	8
younger than years of	8
and the presence of	8
episodic and mild persistent	8
significant reduction in the	8
role of alternative splicing	8
has the potential to	8
alexithymia and asthma control	8
in a subset of	8
to lung function impairment	8
using an ultrasonic flow	8
the present study was	8
persistent and frequent asthmatics	8
mast cells and eosinophils	8
would be higher in	8
of the forced oscillation	8
squared test was used	8
relationship between alexithymia and	8
functional significance of our	8
the mean age years	8
there was a positive	8
higher than the national	8
pulmonary disease and asthma	8
case of a patient	8
there was a strong	8
it has long been	8
in most of the	8
between july and june	8
in the same patient	8
to ascertain asthma in	8
change in fev after	8
was used to identify	8
from childhood to adulthood	8
of air pollution on	8
and mortality in copd	8
reverse transcribed for real	8
development of sensitization to	8
that the majority of	8
with a doctor diagnosis	8
between granzyme b and	8
with asthma and copd	8
allergic disease remains controversial	8
infection in young children	8
bal and breath condensate	8
and is characterized by	8
immune response to infection	8
assess associations between alternative	8
effects of port hedland	8
chronic inflammatory asthma phenotypes	8
modifiable risk factors for	8
with parents and children	8
participants with copd had	8
significant improvement in ef	8
provided ml of blood	8
minimum database for both	8
be considered for recruitment	8
and were current smokers	8
has not been studied	8
with house dust mite	8
consecutive patients who underwent	8
study of consecutive patients	8
in interstitial lung disease	8
associated with a reduced	8
and is funded by	8
by the fact that	8
field and for research	8
to increase the risk	8
rna was isolated and	8
in patients with non	8
reported asthma by age	8
mild episodic and mild	8
in clinically diagnosed artpah	8
with or without asthma	8
respiratory infections and asthma	8
asthma hospital admissions in	8
up to age years	8
be related to the	8
people aged years and	8
the group of patients	8
functionally distinct protein isoforms	8
a broad range of	8
database for both practitioners	8
domain of the a	8
of the upper airway	8
of alternative splicing in	8
in of the patients	8
with progressive dyspnoea and	8
of blood from which	8
and sick building syndrome	8
more likely to develop	8
total ige and specific	8
patients with asthma exacerbations	8
a randomized clinical trial	8
gene can generate structurally	8
per practice in the	8
respiratory pathogens in the	8
there is no evidence	8
by a variety of	8
administration of antenatal corticosteroids	8
and the pathogenesis of	8
of the present study	8
that specific alternatively spliced	8
we hypothesized that specific	8
found to be significantly	8
ages of and years	8
skin prick test with	8
a high degree of	8
emphysema severity in copd	8
studies have suggested that	8
triggers of asthma exacerbations	8
treatment in patients with	8
inflammatory cytokines and chemokines	8
and evening peak flow	8
the relationship between alexithymia	8
it is hypothesized that	8
the natural course of	8
in pulmonary blood flow	8
we also found that	8
alternative splicing and asthma	8
in one of the	8
alternative or aberrant splicing	8
with the high fat	8
the presence of the	8
and years to ascertain	8
with copd and bronchiectasis	8
of asthma and the	8
balb c mice were	8
tumstatin in the airway	8
regulatory t cells in	8
considered for recruitment to	8
analysed by flow cytometry	8
has been demonstrated to	8
a history of asthma	8
cytokine chemokine production was	8
were associated with asthma	8
hospital admissions in children	8
birth and development of	8
was prospectively documented up	8
interstitial lung disease and	8
asthma and airways and	8
escape immune surveillance by	8
symptoms of allergic rhinitis	8
normal values for each	8
did not differ significantly	8
subjects were years of	8
has not been previously	8
an increase in intracellular	8
and is a major	8
asthma and had respiratory	8
the role played by	8
were isolated by ficoll	8
in the differential diagnosis	8
of quality of life	8
and within cell lines	8
and reverse transcribed for	8
specific alternatively spliced asthma	8
paired pulmonary function data	8
underlying cause of death	8
present the case of	8
in the risk of	8
the development of atopy	8
led to increased release	8
the leading cause of	8
improvement in ef and	8
markers of systemic inflammation	8
observational study of consecutive	8
spliced asthma candidate genes	8
prospective longitudinal cohort study	8
has yet to be	8
evidence of bronchopleural fistula	8
between cat exposure before	8
with severe or difficult	8
history of allergic rhinitis	8
following a familiarization test	8
shown to be associated	8
patients with stable asthma	8
of suspected pulmonary embolism	8
the nature of the	8
body size mandibular enclosure	8
was calculated using the	8
at baseline and following	8
methods of assessment of	8
in line with the	8
the most common food	8
of ahr in sarcoidosis	8
of each apnea event	8
the inflammatory response and	8
from which peripheral blood	8
were significantly higher than	8
asthma pathogenesis has not	8
shown to have a	8
may increase the risk	8
the role of early	8
structurally and functionally distinct	8
of the common cold	8
were current or ex	8
allergic rhinitis is a	8
in children to years	8
conflict of interest none	8
a member of the	8
in the early morning	8
the asthma control test	8
on the one hand	8
establish the functional significance	8
study of children with	8
tahs is a longitudinal	8
h o concentration between	8
of asthma medication use	8
similar to that of	8
dendritic cells following incubation	8
predicted and fev fvc	8
those with lung cancer	8
in saturated fat and	8
were found in patients	8
and colleagues showed that	8
asthma phenotypes of severe	8
both adults and children	8
were determined from the	8
there is little evidence	8
these data will be	8
blood from which peripheral	8
ml of blood from	8
inflammatory cells in the	8
prevalence of acid reflux	8
asthma candidate genes contribute	8
is influenced by asthma	8
with asthma and had	8
were former smokers and	8
subjects provided ml of	8
who had their first	8
and the level of	8
is often associated with	8
symptom and peak flow	8
splicing in asthma pathogenesis	8
the last year were	8
did not have osa	8
of port hedland pm	8
blood flow during cpb	8
often used as an	8
volume and molar mass	8
in the induced sputum	8
which a single gene	8
are associated with a	7
allergen exposure increase the	7
th cytokine and il	7
of the most important	7
subjects and patients with	7
and allergen exposure increase	7
was a positive correlation	7
systematic review of randomized	7
in all age groups	7
not associated with higher	7
skin prick tests were	7
of asthma and atopic	7
determine the frequency of	7
ige levels and skin	7
prevalence of symptoms of	7
a limited number of	7
hospital admissions for asthma	7
no differences between the	7
inflammatory disorder of the	7
risk of asthma hospital	7
the disease and the	7
appears to be no	7
by viral respiratory infections	7
is made available under	7
with respiratory tract disease	7
no clinically relevant changes	7
it is associated with	7
significantly higher in patients	7
subsequent development of persistent	7
tests and specific ige	7
of peak expiratory flow	7
it is known that	7
of respiratory viruses associated	7
m and m receptors	7
the national institute of	7
have been reported to	7
for the onset of	7
the activity of the	7
the later development of	7
respiratory tract viral infections	7
is the case with	7
other studies have shown	7
of allergic disease in	7
the aim of our	7
for patients with severe	7
a number of other	7
and treatment of wheezing	7
the relative contribution of	7
and tumor necrosis factor	7
has been demonstrated that	7
may be present in	7
symptoms of asthma in	7
have an impact on	7
the time of exacerbation	7
the first case of	7
the treatment of chronic	7
in children with high	7
asthma and atopic diseases	7
children from birth to	7
can be associated with	7
development of recurrent wheezing	7
a major public health	7
is not known whether	7
the safety and efficacy	7
of the study is	7
have also been shown	7
and asthma medication use	7
allergic diseases in the	7
the treatment of children	7
of the efficacy of	7
may be useful for	7
international license it is	7
the occurrence of asthma	7
specimens were negative for	7
poor asthma control is	7
of children with a	7
children with respiratory tract	7
risk of asthma exacerbation	7
on the association between	7
there was a trend	7
of asthma and wheezing	7
serum levels of ecp	7
deficient type iii interferon	7
the frequency and severity	7
be at increased risk	7
total of patients were	7
a key regulator of	7
presenting to the emergency	7
in seasonal allergic rhinitis	7
we report on a	7
a deficient innate immune	7
a recent study of	7
in the last few	7
of modifiable risk factors	7
deficient innate immune response	7
an increasing number of	7
to determine the effects	7
is a chronic inflammatory	7
a causal relationship between	7
in the first two	7
this has led to	7
it is believed that	7
the case of the	7
national health interview survey	7
high risk for asthma	7
development of sensitization and	7
that this may be	7
in asthmatic subjects in	7
severe combined immune deficiency	7
lower respiratory illness is	7
asthma and related to	7
in asthma and asthma	7
infection in early life	7
with mild persistent asthma	7
to an increase in	7
the development of airway	7
wheezing in the last	7
asthmatic subjects allergic to	7
can be found in	7
induced lower respiratory illness	7
with high rhinovirus genome	7
in elderly asthmatic patients	7
duration of asthma and	7
the prevalence of gerd	7
less than years old	7
of respiratory viral infection	7
study of modifiable risk	7
asthma control medication was	7
of subsequent development of	7
for the study of	7
exacerbations are associated with	7
children and young adults	7
risk for the development	7
factor for the development	7
total ige level was	7
in patients with lung	7
were randomly assigned to	7
that there may be	7
pacifi c society of	7
viruses and bacteria in	7
cells from patients with	7
in the diagnosis and	7
virus infection and allergen	7
are similar to those	7
investigated the effect of	7
diagnosis of asthma or	7
available under a is	7
is associated with severe	7
bacteria in acute asthma	7
illness is increased in	7
consistent with the hypothesis	7
of upper and lower	7
than in single infections	7
is to assess the	7
a positive response to	7
correlates with disease severity	7
with a variety of	7
was used to compare	7
with normal lung function	7
study was carried out	7
a reduced risk of	7
allergy by age years	7
a significant reduction of	7
study is the first	7
patients with persistent asthma	7
studies to date have	7
associated with clinical severity	7
for prevention and treatment	7
a significant proportion of	7
inclusion and exclusion criteria	7
the treatment of severe	7
can be used in	7
shown to be a	7
number of inflammatory cells	7
acute respiratory tract infection	7
for the detection of	7
compared to healthy controls	7
c society of respirology	7
study was approved by	7
tests were positive for	7
related to virus load	7
in the induction of	7
or more of the	7
in children with atopic	7
not been well studied	7
from patients with asthma	7
to determine the frequency	7
study was to estimate	7
the aim was to	7
were found between the	7
the complexity of the	7
infections are the major	7
as well as an	7
the most frequently identified	7
study was designed to	7
to evaluate the role	7
release of inflammatory mediators	7
evaluate the role of	7
asthma respiratory syncytial virus	7
one of the main	7
a is the author	7
despite the use of	7
an odds ratio of	7
a central role in	7
the clinical efficacy of	7
aims of this study	7
children with atopic dermatitis	7
can be used as	7
group than in the	7
the role of rhinovirus	7
compared to those without	7
the aims of this	7
a significant improvement of	7
infancy and asthma and	7
eosinophil major basic protein	7
after the administration of	7
in nasal polyp tissue	7
poor control of asthma	7
response to viral infections	7
the role of virus	7
license it is made	7
at increased risk for	7
exposure increase the risk	7
attention deficit hyperactivity disorder	7
a greater reduction in	7
of asthma and wheeze	7
was associated with lower	7
eosinophil numbers in the	7
in relation to age	7
were invited to participate	7
respiratory syncytial virus disease	7
by bronchial epithelial cells	7
in coinfections than in	7
asthma exacerbations in adults	7
of genes associated with	7
respiratory viruses in children	7
a growing body of	7
to be able to	7
key role in the	7
yet to be determined	7
one of the major	7
has not yet been	7
as a consequence of	7
did not correlate with	7
an effective treatment for	7
infections and the development	7
role in these processes	7
in the control of	7
with the hypothesis that	7
there was no increase	7
lung function in the	7
mild to moderate ea	7
virus load and th	7
treated with inhaled corticosteroids	7
and related to virus	7
bronchial epithelial cells from	7
but it is not	7
made available under a	7
not been studied in	7
there is a strong	7
admitted to the hospital	7
than that in the	7
by the use of	7
and its effect on	7
about the role of	7
at least one of	7
variation in the prevalence	7
asthma is one of	7
experimental rhinovirus infection in	7
of infection in the	7
children hospitalized for wheezing	7
asthma attacks associated with	7
syncytial virus in early	7
of patients who were	7
a cohort of asthmatic	7
been suggested as a	7
presence of eosinophils in	7
significant differences in the	7
was found between the	7
had a sensitivity of	7
of allergic airway inflammation	7
to be at least	7
is defined as a	7
are considered to be	7
was performed with a	7
is a marker of	7
was a significant correlation	7
chart review of all	7
measured before and after	7
in the release of	7
compared with those with	7
the use of antibiotics	7
up to of asthma	7
a reduction in the	7
a protective effect on	7
risk of hospital admission	7
and the degree of	7
the mean duration of	7
led to a significant	7
are also associated with	7
the characteristics of the	7
screening of respiratory tract	7
the increased rate of	7
to be elevated in	7
the management of chronic	7
of budesonide and formoterol	7
six years of life	7
of wheezing disorders in	7
attacks associated with respiratory	7
of genetic and environmental	7
associated with an improvement	7
obstructive pulmonary disease in	7
over a period of	7
as a means of	7
patients with atopic asthma	7
be considered in patients	7
year of life was	7
of respiratory tract samples	7
the increase in the	7
but the presence of	7
epidemic of asthma exacerbations	7
assess the efficacy of	7
of the disease has	7
with recurrent airway obstruction	7
is the most important	7
the presence of specific	7
previous diagnosis of asthma	7
severe asthma research program	7
to estimate the prevalence	7
confirm the diagnosis of	7
acute asthma in children	7
the british thoracic society	7
a marked increase in	7
be associated with an	7
most likely due to	7
and exhaled nitric oxide	7
diagnosis of allergic rhinitis	7
role in acute asthma	7
increased in asthma and	7
and bacteria in acute	7
has not been well	7
in the clinical setting	7
children in hong kong	7
high risk of developing	7
levels were measured by	7
to estimate the incidence	7
the result of the	7
measures of lung function	7
the intensive care unit	7
development and validation of	7
treatment with inhaled corticosteroids	7
prevalence of food allergy	7
risk of subsequent development	7
this study showed that	7
further research is needed	7
did not differ in	7
the clinical course of	7
a randomized trial of	7
the median age of	7
both asthma and copd	7
lung function and asthma	7
are shown in table	7
treatment of wheezing disorders	7
the association between viral	7
studies have investigated the	7
to virus load and	7
a critical review of	7
in the first six	7
the most common trigger	7
disorders in preschool children	7
is characterized by a	7
well as in the	7
of a year old	7
were detected in the	7
was no increase in	7
use of inhaled corticosteroids	7
tezepelumab in patients with	7
of kipyv and wupyv	7
according to international guidelines	7
under a is the	7
frequency and severity of	7
were not statistically different	7
the possible role of	7
be safe and effective	7
especially in patients with	7
were no significant changes	7
high risk of asthma	7
thymic stromal lymphopoietin in	7
of allergies and asthma	7
may be explained by	7
the prevention and treatment	7
and total ige levels	7
associated with increased asthma	7
respiratory tract infection and	7
did not find a	7
the dose of inhaled	7
an important impact on	7
association between viral infection	7
of viral respiratory tract	7
safe and effective treatment	7
of the natural history	7
have an important role	7
independent risk factors for	7
lung function at age	7
before years of age	7
have not been investigated	7
of influenza vaccination in	7
of asthma hospital admissions	7
a great deal of	7
wheezing disorders in preschool	7
function in patients with	7
we have shown that	7
respiratory tract infections and	7
an independent risk factor	7
an improvement in asthma	7
and to a lesser	7
was detected in of	7
on the surface of	7
in patients with idiopathic	7
for a total of	7
on the presence of	7
the prevalence of sensitization	7
the development of atopic	7
significant increase in the	7
respiratory illness is increased	7
and a reduction in	7
symptoms and asthma medication	7
of inflammatory cells in	7
it is made available	7
of food allergy in	7
course of the disease	7
a role for eosinophils	7
and risk of subsequent	7
should be aware of	7
children with respiratory disease	7
the pathogenesis of allergic	7
the small number of	7
coinfections than in single	7
prevalence of asthma is	7
by a combination of	7
found to be more	7
of allergy and clinical	7
asthmatic subjects in vivo	7
a period of months	7
patients with allergic asthma	7
with obstructive sleep apnea	7
in an animal model	7
in horses with severe	7
it is not possible	7
of the airways that	7
asian pacifi c society	7
in the event of	7
been well studied in	7
been linked to asthma	7
children and adults in	6
and subsequent development of	6
the prevalence of acid	6
severe lower respiratory tract	6
leads to activation of	6
her past medical history	6
study of patients with	6
the basis of the	6
safe and well tolerated	6
mice were immunized with	6
area under the curve	6
in airway inflammation and	6
they were asked to	6
to the release of	6
both before and after	6
is a leading cause	6
had a higher mean	6
the main cause of	6
both th and th	6
to be successful in	6
a beneficial effect on	6
such as those of	6
and a greater reduction	6
children with asthma exacerbations	6
of sensitization and allergic	6
of proinflammatory cytokines and	6
this was followed by	6
viral exacerbation of asthma	6
exacerbations in patients with	6
being the most common	6
there are more than	6
there was no change	6
did not show a	6
and the release of	6