quadgram

This is a table of type quadgram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

quadgram	frequency
in the presence of	928
severe acute respiratory syndrome	830
porcine reproductive and respiratory	649
reproductive and respiratory syndrome	648
and respiratory syndrome virus	576
has been shown to	556
in the absence of	480
in the pathogenesis of	470
acute respiratory syndrome coronavirus	444
an important role in	438
of type i ifn	413
as well as the	408
middle east respiratory syndrome	392
in the treatment of	387
for the treatment of	367
the innate immune system	357
peripheral blood mononuclear cells	357
the innate immune response	346
of this study was	343
this study was to	334
of the innate immune	315
east respiratory syndrome coronavirus	315
the aim of this	302
have been shown to	287
on the other hand	284
aim of this study	284
play an important role	279
in the context of	276
in vitro and in	276
the central nervous system	252
type i ifn signaling	249
vitro and in vivo	249
play a role in	247
of type i interferon	230
for the development of	228
of type i ifns	226
as a result of	222
as well as in	220
was found to be	218
cd and cd t	218
at the time of	217
of porcine reproductive and	215
in the development of	214
the type i ifn	214
type i and type	212
of the immune response	209
been shown to be	208
in the regulation of	207
innate and adaptive immune	206
of severe acute respiratory	201
of cd t cells	200
in the case of	196
to be involved in	194
in the present study	194
type i ifn production	185
and cd t cells	183
of hepatitis c virus	181
these results suggest that	179
innate and adaptive immunity	175
a critical role in	174
of the immune system	174
the present study was	173
these results indicate that	173
cd t cells in	172
on the basis of	171
t t t t	171
was used as a	171
the type i interferon	170
herpes simplex virus type	167
it has been shown	158
in a mouse model	158
important role in the	158
of the type i	158
porcine epidemic diarrhea virus	157
is one of the	157
a mouse model of	156
be involved in the	156
our results suggest that	155
in the induction of	155
patients with chronic hepatitis	155
specific cd t cells	153
a pivotal role in	153
type i ifn response	151
t cells in the	151
cells were treated with	151
these data suggest that	151
a role in the	149
and adaptive immune responses	149
studies have shown that	149
respiratory syncytial virus infection	148
cells were infected with	148
acute respiratory distress syndrome	147
type i interferon production	143
plays an important role	141
the production of ifn	141
the activation of the	141
the expression of the	140
at the end of	139
one of the most	138
has been reported to	137
hepatitis c virus infection	136
rift valley fever virus	136
compared to corresponding hc	136
cells were transfected with	136
has been shown that	134
of the present study	134
role in the pathogenesis	134
of interferon regulatory factor	134
to the development of	133
these results demonstrate that	133
release of svegf and	132
innate immune response to	132
abstract case report text	132
association between malaria and	132
in the activation of	131
induction of type i	129
at the same time	129
are involved in the	128
with chronic hepatitis c	128
for the presence of	125
vascular endothelial growth factor	124
as shown in fig	123
i and type iii	123
no relationships to disclose	122
in contrast to the	122
a key role in	122
in the control group	121
of influenza a virus	121
in the form of	121
the results showed that	121
a significant increase in	121
a member of the	121
production of type i	120
in patients with severe	120
of cd and cd	118
the antiviral activity of	118
in addition to the	118
used in this study	118
for the first time	117
it is possible that	116
in the group of	115
type i interferon signaling	115
in the sera of	115
of type i and	114
transducer and activator of	113
in patients with chronic	113
influenza a virus infection	112
cd t cell responses	112
in the expression of	112
and activator of transcription	112
cell responses in the	111
to the activation of	110
the aim of the	109
it is important to	109
we found that the	109
the majority of the	109
signal transducer and activator	109
type i interferon response	109
a large number of	109
antibodies were detected in	108
cd cd t cells	108
cd t cells and	108
at the site of	108
investigate the role of	107
cells were incubated with	107
the induction of ifn	106
results indicate that the	106
we are currently investigating	106
in the generation of	105
the end of the	104
the role of the	104
to investigate the role	104
present study was to	104
in the innate immune	104
be presented at the	104
of human collectins in	103
of type i interferons	103
the expression of human	103
expression of human collectins	103
in the united states	103
with special emphasis on	102
lectin pathway of complement	102
human collectins in normal	102
in the central nervous	102
the group of divers	102
iga antibody to type	102
have been found to	102
our results indicate that	102
of genes involved in	101
the lectin pathway of	101
cd t cells were	100
cytokine tumour necrosis factor	100
the association between malaria	99
of svegf and svegfr	99
of middle east respiratory	99
human peripheral blood mononuclear	99
were found to be	99
as shown in figure	99
the expression of ifn	98
an increase in the	98
the immune response to	96
has been demonstrated in	96
in an attempt to	96
as compared to the	95
for the detection of	95
type i ifn in	95
was shown to be	95
we have developed a	94
of herpes simplex virus	94
the presence of a	94
compared to healthy controls	94
expression of type i	93
type i and iii	93
it was found that	93
in the release of	93
have been associated with	93
did not correlate with	93
is associated with a	93
on the surface of	93
we have shown that	93
in cells infected with	93
could be detected in	92
a major role in	92
in the respiratory tract	92
we have demonstrated that	91
a wide range of	91
play a pivotal role	91
patients with and without	91
were significantly higher in	90
i and type ii	90
may be involved in	90
to be associated with	90
been reported to be	90
in the lungs of	90
was to investigate the	89
presence or absence of	89
of the central nervous	89
cells as well as	88
to play a role	87
study was to determine	87
chronic obstructive pulmonary disease	87
pivotal role in the	87
these findings indicate that	87
study was to evaluate	86
for the induction of	86
little is known about	86
with a history of	86
well as in the	86
vivo and in vitro	86
in vivo and in	86
cells were isolated from	86
the presence or absence	85
west nile virus infection	85
a central role in	85
balb c mice were	85
a crucial role in	85
in the control of	84
of innate and adaptive	84
the severe acute respiratory	84
with severe acute respiratory	84
and the development of	83
in the production of	83
the expression of cd	83
in vitro stimulation of	83
we were able to	82
the host immune response	82
is involved in the	82
in the number of	82
in this study we	82
it should be noted	82
by the fact that	82
the production of type	81
the release of the	81
response to viral infection	81
due to differences in	81
h n influenza virus	81
only in the presence	81
may be associated with	81
we have previously shown	80
efficacy and safety of	80
after in vitro stimulation	80
also been shown to	80
classical swine fever virus	79
by hepatitis c virus	79
the development of the	79
there was no significant	79
is induced by type	79
the fact that the	78
of the cellular immune	78
were included in the	78
production in response to	78
increased the expression of	78
inducible nitric oxide synthase	78
of chronic hepatitis b	77
in type i ifn	77
part of the innate	77
reduced in the presence	77
in the majority of	77
role in modulation of	77
of respiratory syncytial virus	77
may contribute to the	76
and the ability to	76
should be noted that	76
of this study is	76
for up to weeks	76
have previously shown that	76
and tumor necrosis factor	75
is dependent on the	75
the jak stat pathway	75
play a key role	75
been found to be	75
have been used for	75
in a variety of	75
on the cell surface	75
both innate and adaptive	75
it has been reported	75
the cellular immune responses	75
responses in the lung	75
cells in response to	75
hek t cells were	75
key role in the	74
the effect of the	74
been shown to induce	74
in response to viral	74
amino acid substitution in	74
respiratory syndrome coronavirus infection	73
this study is to	73
are currently investigating the	73
cd t cells from	73
in a cohort of	73
of hepatitis b virus	73
have shown that the	73
was significantly higher in	73
the regional lymph nodes	73
the presence of the	73
a negative regulator of	72
the goal of the	72
these data indicate that	72
and the presence of	72
in balb c mice	72
aim of the present	72
the adaptive immune response	72
was not altered by	71
and cd t cell	71
a large panel of	71
of rift valley fever	71
type i ifn induction	71
to examine the effects	71
examine the effects of	71
to the induction of	71
mitochondrial antiviral signaling protein	71
major histocompatibility complex class	71
of nk cells with	71
had no effect on	70
of mouse hepatitis virus	70
from healthy blood donors	70
were detected in the	70
white blood cells and	70
of the inflammatory cytokines	70
terminal part of the	70
was not associated with	70
of a number of	70
in the frequencies of	70
as demonstrated by flow	69
a negative feedback regulation	69
the total number of	69
blood cells and platelets	69
patients of bronchial asthma	69
in the oral mucosa	69
presence of dendritic cells	69
resulted in a significant	69
will be presented at	69
demonstrated by flow cytometry	69
expression of tlr on	69
to activate nk cells	69
as well as a	69
trying to identify the	69
blood samples were collected	69
is essential for the	69
have been reported to	69
asthma with allergic rhinitis	69
healthy blood donors were	69
of bronchial asthma with	69
in patients of bronchial	69
bronchial asthma with allergic	69
the presence of complement	69
complications in type diabetes	68
and allergic airway inflammation	68
that the majority of	68
from first to final	68
first to final visit	68
provide an insight of	68
expression of cd and	68
presence of clonally expanded	68
project could provide an	68
mala s for h	68
in presence of dendritic	68
addition of dendritic cells	68
mbl levels and mbl	68
the formation of mbp	68
the expression of cla	68
currently trying to identify	68
the majority of responses	68
type i ifn receptor	68
the effects of hyperbaric	68
any of the examined	68
presented at the conference	68
or the ear skin	68
of tlr on dcs	68
levels and activity were	68
the presence of clonally	68
host innate immune response	68
in this project could	68
immunity in the lung	68
and their related molecules	68
mbl levels and activity	68
with chronic hepatitis b	68
in the mbl gene	68
with a th phenotype	68
t dm patients with	68
critical role in modulation	68
was reduced in the	68
is increasingly used as	68
of nk cells may	68
iga protease activity of	68
increased levels of igg	68
lxrs and their related	68
with the exception of	68
the virus nonstructural protein	68
the inflammatory cytokines il	68
the pathogenesis of ae	68
in ms from stockholm	68
and hc from stockholm	68
of mhc class i	68
the a a receptor	68
the group of control	68
mbl double ko animals	68
for factor h binding	68
serum mbl levels were	68
assays for antiviral activity	68
in the normoalbuminuric group	68
human immunodeficiency virus type	68
could provide an insight	68
of the examined s	68
than in the normoalbuminuric	68
polymorphisms in the mbl	68
with nephropathy than in	68
collectins in normal colon	68
this project could provide	68
are currently trying to	68
results will be presented	68
on the presence of	68
the addition of dendritic	68
proliferating cells were found	68
lactobacillus and bifidobacterium spp	68
group of control donors	68
in chronic hepatitis c	68
intron of the mbl	68
the oral mucosa and	68
but not from sassari	68
of iga protease activity	68
outside the pressurized chamber	68
asthma and allergic airway	68
of hyperbaric exposure on	68
effects of hyperbaric exposure	68
the frequency of mt	68
patients with nephropathy than	68
some time to monitor	67
used as antiviral and	67
it is likely that	67
in the lectin pathway	67
induced by type i	67
all ifn species are	67
nk cells in vitro	67
time to monitor patients	67
type i ifn expression	67
the results will be	67
species are potentially immunogenic	67
the development of a	67
these assays require laborious	67
may be related to	67
monitor patients on ifn	67
these findings suggest that	67
bioavailability varies with ifn	67
increase in the release	67
laborious titrations making them	67
ifn species are potentially	67
species and mode of	67
first line of defense	67
to monitor patients on	67
assays require laborious titrations	67
the objective of this	67
them unsuitable for large	67
titrations making them unsuitable	67
immune response towards a	67
in the presence or	67
increasingly used as antiviral	67
for some time to	67
varies with ifn species	67
antiviral and immunomodulatory therapies	67
pathway of complement activation	67
as antiviral and immunomodulatory	67
and mode of administration	67
used for some time	67
with ifn species and	67
making them unsuitable for	67
and all ifn species	67
been used for some	67
require laborious titrations making	67
new and better reporter	67
an attempt to find	67
patients on ifn biologicals	67
play a major role	67
ifn species and mode	67
the role of mbl	67
is supported by the	66
soluble vascular endothelial growth	66
of fizz and ym	66
svegf and svegfr concentrations	66
living on the coast	66
for malaria in children	66
on the coast of	66
complement activation through the	66
of complement activation through	66
plasma svegf and svegfr	66
induced release of svegf	66
highthroughput global proteome analysis	66
in sentinel lymph nodes	66
the induction of type	66
cells of c def	66
hydrophobic interaction chromatography and	66
invertebrate pattern recognition molecule	66
and transduced cell lines	66
the development of loss	66
mrna in cd b	66
depended on intercellular contact	66
our understanding of the	66
between the two groups	66
of ae to modulate	66
a responsiveness ex vivo	66
and mbl masp activity	66
differences in the frequencies	66
between malaria and malnutrition	66
children living on the	66
the development of immunological	66
cultures of sarcoid origin	66
is likely to be	66
a predisposing factor for	66
to be able to	66
our observation that c	66
survival and growth of	66
and have no enhanced	66
svegf and svegfr from	66
a unique possibility to	66
control and transduced cell	66
the control and transduced	66
like domain of ccf	66
the host innate immune	66
capacity of ae to	66
response towards a th	66
for survival and growth	66
involved in the pathogenesis	66
selected on the basis	66
the coast of kenya	66
objective of this study	66
the protective effect of	66
binding regions of ospe	66
at different time points	65
type i ifn responses	65
has been reported that	65
was associated with a	65
tumor necrosis factor alpha	65
at an moi of	65
hepatitis b surface antigen	65
infection is associated with	65
no significant difference in	64
is required for the	64
an important role for	64
with an increase in	64
study was to investigate	64
was found in the	64
in accordance with the	64
hepatitis c virus replication	64
type i interferon induction	63
infection of mice with	63
similar to that of	63
were added to the	63
plays a role in	63
the authors declare that	63
the presence of an	62
in the range of	62
production of inflammatory cytokines	62
suppressor of cytokine signaling	62
in the response to	62
this work was supported	62
treatment of chronic hepatitis	62
at the level of	62
the expression levels of	62
with the help of	61
and type i ifn	61
inflammatory cytokines and chemokines	61
plays a pivotal role	61
in patients with covid	61
in hek t cells	61
a high degree of	61
by the induction of	61
be detected in the	61
which is associated with	61
for the production of	61
to determine whether the	61
innate immune responses to	61
has been associated with	61
in the course of	61
results showed that the	60
may be due to	60
is known about the	60
type i ifn and	60
included in this study	60
was observed in the	60
is associated with the	60
in the management of	60
there was no difference	60
national institutes of health	60
the site of infection	60
in mice infected with	60
work was supported by	60
the first line of	60
type i interferon responses	60
type i interferon and	60
the antiviral effect of	60
of natural killer cells	59
activation of the ifn	59
at a dose of	59
our aim was to	59
in the bone marrow	59
in peripheral blood mononuclear	59
cytokines such as tnf	59
central nervous system of	59
by flow cytometry and	59
our data suggest that	59
was no significant difference	59
inhibits type i interferon	58
the treatment of chronic	58
included in the study	58
the vast majority of	58
as a consequence of	58
we have found that	58
and the risk of	58
higher levels of il	58
is part of the	58
a better understanding of	58
or in combination with	58
cirrhosis and hepatocellular carcinoma	58
has been found to	58
in the design of	58
in the cns of	58
the innate and adaptive	58
play a central role	58
the nature of the	57
in response to virus	57
at the onset of	57
under the control of	57
during influenza virus infection	57
could be used to	57
in the recognition of	57
a final concentration of	57
patients with severe acute	57
type i interferons in	57
of the study was	57
the purpose of this	57
of the expression of	57
identification and characterization of	57
to the severity of	57
the expression of mhc	56
have been demonstrated to	56
has also been shown	56
analyses were performed using	56
may play a role	56
the results of this	56
play a critical role	56
would be interesting to	56
been implicated in the	56
the expression of type	56
hepatitis c virus ns	56
during the course of	55
it has been suggested	55
of innate immune responses	55
central role in the	55
study was carried out	55
human respiratory syncytial virus	55
on the expression of	55
type i interferon receptor	55
with respiratory syncytial virus	55
are present in the	55
in the peripheral blood	55
of the ifn response	55
to the use of	55
in vero e cells	55
activation of nk cells	55
compared to the controls	55
for the expression of	55
and the expression of	54
the activity of the	54
in response to infection	54
were used as a	54
remains to be determined	54
has been demonstrated to	54
influenza a virus ns	54
previously been shown to	54
antiviral innate immune response	54
patients with severe covid	54
it was shown that	54
the secretion of ifn	54
histocompatibility complex class i	54
was not due to	54
shown to be a	54
is thought to be	54
increase the expression of	54
was significantly associated with	54
was not observed in	54
role in the induction	54
it has been demonstrated	54
were randomized to receive	54
blood samples were obtained	53
the inhibitory effect of	53
alone or in combination	53
in a murine model	53
was considered statistically significant	53
the influenza a virus	53
been shown to increase	53
is not fully understood	53
cells in peripheral blood	53
innate immune responses in	53
a l p r	53
were isolated from the	53
can be used for	53
of the role of	53
the importance of the	53
the treatment of covid	53
ifnar fl fl mice	53
of th and th	53
plays a critical role	53
the first year of	53
hepatitis b virus infection	53
results in the activation	53
by the presence of	53
can be detected in	53
the treatment of patients	53
type i ifns and	53
was significantly increased in	52
l p r e	52
for min at room	52
at all time points	52
over a period of	52
safety and efficacy of	52
the host response to	52
the ability of the	52
is a member of	52
o u r n	52
not certified by peer	52
the presence of ifn	52
we have investigated the	52
we have previously demonstrated	52
license to display the	52
the stability of the	52
is the author funder	52
the mechanisms underlying the	52
can be used to	52
medrxiv a license to	52
there was no correlation	52
to contribute to the	52
the expression of il	52
a first line of	52
at the age of	52
was not certified by	52
r n a l	52
min at room temperature	52
a license to display	52
u r n a	52
display the preprint in	52
used as a control	52
certified by peer review	52
p r o o	52
of tumor necrosis factor	52
granted medrxiv a license	52
n a l p	52
has been suggested that	52
it would be interesting	52
that the expression of	52
macrophages and dendritic cells	52
which was not certified	52
r o o f	52
who has granted medrxiv	52
j o u r	52
induce the expression of	52
total rna was extracted	52
of chronic hepatitis c	52
has granted medrxiv a	52
to display the preprint	52
negative feedback regulation of	51
results of this study	51
the mechanism by which	51
incubated for h at	51
stimulated in vitro with	51
of the complement system	51
the hepatitis c virus	51
treatment of patients with	51
cells were stimulated with	51
leading to the activation	51
copyright holder for this	51
to a lesser extent	51
of a patient with	51
by cd t cells	51
a single amino acid	51
was to evaluate the	51
i and iii ifns	51
at a concentration of	51
and tumour necrosis factor	51
be due to the	51
it is known that	51
influenza a h n	51
innate immune response in	51
role of type i	51
mice were immunized with	51
the efficacy and safety	51
were incubated with the	51
both in vitro and	51
an essential role in	50
was added to the	50
studies are needed to	50
a significant decrease in	50
this is supported by	50
cellular immune responses to	50
of angelica tenuissima nakai	50
has previously been shown	50
cells are involved in	50
low levels of ifn	50
of west nile virus	50
has not yet been	50
a role for the	50
patients and healthy controls	50
does not seem to	50
rna was extracted from	50
regulation of type i	50
h at room temperature	50
is not due to	49
in order to study	49
a result of the	49
by the innate immune	49
analysis was performed using	49
of the transcription factor	49
by the addition of	49
was measured by elisa	49
type i ifns in	49
first year of life	49
have the capacity to	49
response to virus infection	49
no significant differences in	49
of porcine epidemic diarrhea	49
was associated with higher	49
this is the first	49
is crucial for the	49
our findings suggest that	49
has been implicated in	49
is responsible for the	49
higher than that in	49
their role in the	49
we propose that the	49
to porcine reproductive and	49
the formation of the	49
induces the expression of	49
study was to examine	48
the nuclear translocation of	48
chronic hepatitis c virus	48
t cell responses in	48
purpose of this study	48
was found to have	48
cells were seeded in	48
that the absence of	48
tested the hypothesis that	48
of experimental autoimmune encephalomyelitis	48
the kinetics of the	48
the regulation of the	48
levels were higher in	48
of stat and stat	48
high levels of ifn	48
in the immune response	48
have previously demonstrated that	48
that the use of	48
is independent of the	48
induced type i ifn	48
i interferon production by	48
of the adaptive immune	48
have the potential to	48
that there is no	48
the copyright holder for	48
in a patient with	48
study was undertaken to	48
aim of the study	48
to type i ifn	47
in patients infected with	47
dependent on the presence	47
is known to be	47
in severe acute respiratory	47
first years of life	47
is important to note	47
the complexity of the	47
patients with multiple sclerosis	47
in the last decade	47
the authors declare no	47
there was a significant	47
with increased levels of	47
to the production of	47
significantly increased in the	47
we previously reported that	47
in mice immunized with	47
the role of ifn	47
r h m k	47
been associated with increased	47
the surface expression of	47
with type i ifn	47
is a target for	47
higher in patients with	47
ifn in response to	47
was no correlation between	47
we tested the hypothesis	47
a significant reduction in	47
been shown to inhibit	47
with the development of	47
could play a role	47
the early stages of	47
line of defense against	46
in vitro stimulation with	46
and transforming growth factor	46
on cd t cells	46
was performed using the	46
the major source of	46
in response to ifn	46
in the first year	46
cell lines in vitro	46
human airway epithelial cells	46
in the inhibition of	46
response was observed in	46
the production of il	46
the expression of tlr	46
known to play a	46
liver cirrhosis and hepatocellular	46
type i interferon in	46
group than in the	46
the absence of ifn	46
of inflammatory cells into	46
a higher risk of	46
were similar in both	46
of both innate and	46
studied the effect of	46
order to study the	46
proinflammatory cytokines such as	46
measured by flow cytometry	46
examined the effects of	46
higher than that of	46
significantly higher in patients	46
the immune responses of	46
at least in part	46
both human and mouse	46
have been identified in	46
found to be significantly	46
were increased in the	45
cells in the pathogenesis	45
was higher in the	45
a broad spectrum of	45
concentration of ng ml	45
expression of genes involved	45
have been reported in	45
both mouse and human	45
influenza virus infection in	45
and the production of	45
a major cause of	45
type i ifns are	45
to the site of	45
the first years of	45
case report text introduction	45
their ability to produce	45
used for treatment of	45
the study was to	45
type i and ii	45
may be attributed to	45
as a marker of	45
inhibit the replication of	45
and type iii ifns	45
for the activation of	45
also been found to	45
in the light of	45
important to note that	45
was performed to detect	45
were observed in patients	45
of mhc class ii	45
a in patients with	45
studies have demonstrated that	45
could be used in	45
the course of infection	45
mechanism of action of	45
examined the expression of	45
added to the cells	45
the antiviral effects of	45
produce large amounts of	45
cells was significantly higher	45
before and after the	45
lower respiratory tract infections	45
for h at room	45
the pathogenesis of ms	45
of nk cells in	44
was carried out to	44
patients who do not	44
is the most common	44
to be activated by	44
of mice with the	44
a total of patients	44
significantly higher in the	44
could lead to a	44
the porcine reproductive and	44
to influenza a virus	44
was significantly higher than	44
the severity of the	44
the early phase of	44
role in the innate	44
for more than months	44
study is to evaluate	44
in infected cells and	44
the presence of anti	44
mhc class ii and	44
there were no significant	44
hepatitis c virus rna	44
for their ability to	44
holder for this this	44
and the induction of	44
compared to the control	44
as well as some	44
this version posted august	44
the control group was	44
is to evaluate the	44
was to determine whether	44
to be the case	44
for this this version	44
is not included in	44
syncytial virus infection in	44
this this version posted	44
we recently reported that	44
at the interface of	44
results suggest that the	44
been shown to activate	44
are listed in table	44
positive cells in the	44
an important regulator of	44
be a risk factor	43
have been implicated in	43
is consistent with the	43
of alternatively activated macrophages	43
could serve as a	43
at a moi of	43
natural killer cells in	43
for at least months	43
the mechanism of action	43
innate immune response by	43
in a model of	43
studies revealed that the	43
involved in the regulation	43
play a crucial role	43
a monoclonal antibody against	43
in order to understand	43
has also been found	43
their ability to respond	43
g for min at	43
and the activation of	43
of a set of	43
animal care and use	43
natural killer cell cytotoxicity	43
has been demonstrated that	43
for the identification of	43
be explained by the	43
systematic review and meta	43
the development of vaccines	43
class ii cytokine receptor	43
to play a pivotal	43
mgfapcre ifnar fl fl	43
in the study and	43
the e ubiquitin ligase	43
care and use committee	43
with fetal bovine serum	43
compared to healthy individuals	43
a type i ifn	43
ability to respond to	43
regulate the expression of	43
the adaptive immune system	43
an important part of	42
we also examined the	42
was found that the	42
was approved by the	42
patients with a history	42
in response to the	42
is not required for	42
first line of defence	42
t cells that are	42
cd t cell response	42
been used as a	42
sera from patients with	42
the immune status of	42
monocytes and dendritic cells	42
was to examine the	42
t cells were cultured	42
critically ill patients with	42
mhc class i molecules	42
the first step in	42
specific t cell responses	42
line of defence against	42
t cells into the	42
the exact role of	42
a cohort of children	42
the ability of these	42
be related to the	42
a systematic review and	42
has the potential to	42
was not influenced by	42
the effect of ifn	42
cells were washed with	42
has also been reported	42
increased risk of developing	42
one of the leading	42
analysed by flow cytometry	42
the production of tnf	42
bovine viral diarrhea virus	42
lack of response to	42
in the formation of	42
for the interaction with	42
in patients treated with	42
it remains to be	42
and increased levels of	42
of the patients was	42
our results show that	42
in the setting of	42
in human and murine	42
was measured by a	42
i ifn in response	41
of a variety of	41
increased susceptibility to infections	41
by increased expression of	41
order to understand the	41
the pathogenesis of asthma	41
of single nucleotide polymorphisms	41
c a and c	41
of cytokines and chemokines	41
rna in infected cells	41
mhc class i and	41
associated with suppression of	41
cytokines such as il	41
cd t cells to	41
the cytokine response to	41
as a control group	41
a has been shown	41
the number of ifn	41
of the leading causes	41
the initial phase of	41
the absence of any	41
a type i interferon	41
a significant role in	41
both cd and cd	41
immune response in the	41
its ability to bind	41
to play an important	41
by plasmacytoid dendritic cells	41
was detected in the	41
also play an important	41
significantly associated with the	41
to be sensitive to	41
similar results were obtained	41
required in order to	41
have not been fully	41
in parallel with the	41
adaptive immune responses to	41
for h and then	41
by the formation of	41
stimulation of t cells	41
a virus ns protein	41
in patients who received	41
and the majority of	41
but not in the	41
a possible role of	41
in combination with ribavirin	41
blood samples were drawn	41
associated with the disease	41
t cells and the	41
produce type i ifn	41
memory cd t cells	41
this group of patients	41
the subsequent development of	41
the site of injection	41
in a significant increase	41
i ifn production in	41
did not result in	41
on the development of	40
we have examined the	40
have important implications for	40
a broad range of	40
activation of the complement	40
cd and cd on	40
in this study is	40
can act as an	40
model for studying the	40
induction of cell death	40
suggest that there is	40
in human monocytes and	40
at increased risk of	40
in critically ill patients	40
found to be sensitive	40
c mice were immunized	40
t cell responses to	40
the mechanisms by which	40
proliferation in response to	40
in plasmacytoid dendritic cells	40
data presented in this	40
but not sufficient for	40
important implications for the	40
mediated type i interferon	40
to produce type i	40
present study was undertaken	40
lower than that in	40
detected in the sera	40
can be applied to	40
c bl mice were	40
specific cd t cell	40
pcr was performed with	40
peptides corresponding to the	40
were then treated with	40
that expression of the	40
a period of months	40
the complement system is	40
and play an important	40
trials for the treatment	40
between innate and adaptive	40
expression in peripheral blood	40
the induction of cell	40
of mice infected with	40
as a positive control	40
in order to determine	40
expression was evaluated by	40
that are known to	40
has been used as	40
respiratory syndrome virus infection	40
long been known to	40
these data demonstrate that	40
to increased susceptibility to	40
the proliferation of the	40
on the function of	40
were collected and the	40
better understanding of the	40
in a number of	40
it was reported that	40
a family history of	40
important part of the	40
the ability to activate	40
was measured by flow	40
a wide variety of	40
investigated the effect of	40
is the first step	40
and the number of	40
the treatment of various	40
the concentration of ifn	40
is based on the	40
a potent inhibitor of	39
on peripheral blood mononuclear	39
involved in host defense	39
we found that il	39
for chronic hepatitis c	39
to be limited to	39
believed to play a	39
and stability of the	39
associated with poor prognosis	39
the early stage of	39
in healthy individuals and	39
significantly higher levels of	39
test the effect of	39
t cells were transfected	39
cd and cd were	39
t cells were isolated	39
investigated the ability of	39
and then infected with	39
and can be used	39
we examined the effects	39
peripheral blood stem cell	39
the data presented in	39
we have tested the	39
cells during the acute	39
without the addition of	39
associated with a type	39
time pcr was performed	39
were higher in the	39
single amino acid substitution	39
during the observation period	39
the immunomodulatory effect of	39
there is increasing evidence	39
virus infection in mice	39
aim was to investigate	39
was compared to the	39
the development of th	39
cultured with or without	39
by the use of	39
crystal structure of a	39
the induction of the	39
we recently demonstrated that	39
in the current study	39
we identified a novel	39
to test the effect	39
of blood mononuclear cells	39
plays a crucial role	39
respiratory syncytial virus bronchiolitis	39
of both human and	39
macrophages as well as	39
and adaptive immunity in	39
peripheral blood samples were	39
and the balance between	39
the innate antiviral response	39
immune response and is	39
a reduction in the	39
nk cells in the	39
syndrome coronavirus m protein	39
and compared to the	39
acid substitution in the	39
high degree of homology	39
is an important regulator	39
with porcine reproductive and	39
respiratory syndrome coronavirus m	39
the expression level of	39
be interpreted with caution	39
to the lack of	39
for the control of	39
the first time that	39
in this group of	39
our results showed that	39
of the vaccinia virus	39
a lower risk of	39
genes involved in the	39
these genes were significantly	38
can be found in	38
in some cases the	38
the cells were then	38
of heat shock protein	38
the cell cycle and	38
in this study had	38
shown in figure a	38
promote the formation of	38
the effect of these	38
of the ns protein	38
cells play an important	38
an increased production of	38
to the nucleus and	38
and healthy controls were	38
of this cytokine on	38
to the difference in	38
a major source of	38
does not bind to	38
of a range of	38
a decrease in the	38
immunity in response to	38
and the role of	38
no conflict of interest	38
we suggest that the	38
the absence of the	38
we studied the effect	38
study was to analyse	38
protein as well as	38
regulation of adaptive immunity	38
is critical for the	38
be critical for the	38
at various times after	38
with high levels of	38
n and h n	38
is characterized by recurrent	38
cells has been demonstrated	38
in the control and	38
were more pronounced in	38
serve as a useful	38
proliferation of b cells	38
and a combination of	38
to investigate the association	38
was not mediated by	38
more frequent in the	38
mice compared to wildtype	38
cell suspensions were prepared	38
play important roles in	38
host innate immune responses	38
of high and low	38
to the group of	38
the maturation of the	38
investigate the prevalence of	38
institute of medical microbiology	38
which was found to	38
which may be related	38
in the liver of	38
and production of inflammatory	38
be responsible for the	38
to any of the	38
found that the majority	38
days after the last	38
cells were assayed for	38
a combination of il	38
in turn results in	38
major source of ifn	38
cells were stained with	38
which was not observed	38
such as tnf and	38
have not been elucidated	38
the genes of interest	38
further characterization of the	38
be of value in	38
produced higher levels of	38
not influenced by the	38
to the pathogenesis of	38
to the impairment of	38
of hla class i	38
have a higher risk	38
reported to be involved	38
is associated with increased	38
that they have no	38
the immune response in	38
the activation of nf	38
and is related to	38
sera from ms patients	38
by the development of	38
that is produced by	38
of cd t cell	38
at years of age	38
mast cell degranulation and	38
the results of the	38
and is associated with	38
in any of the	38
to the expression of	38
was examined by western	38
induced by treatment with	38
were cultured with or	38
the capacity to induce	38
have been identified as	38
was closely related to	38
is a predictor of	38
of c a and	37
will also be presented	37
not to be the	37
patients compared to the	37
cell activation in the	37
were incubated for h	37
the cytolytic activity of	37
the course of the	37
is an important part	37
of molecular and cellular	37
we show here that	37
showed no difference in	37
the light of the	37
no effect on the	37
an inflammatory response to	37
the simultaneous expression of	37
be used to identify	37
form the basis for	37
interactions are crucial for	37
in the cytoplasm of	37
has been identified as	37
pattern recognition receptors of	37
is associated with poor	37
model of allergic asthma	37
to investigate the prevalence	37
increasing the number of	37
have long been known	37
how the immune system	37
and characterization of a	37
the role of anti	37
and is dependent on	37
focus has been on	37
we first evaluated the	37
examined by western blotting	37
cytokines and chemokines in	37
supported by the fact	37
receptors of the innate	37
amino acid residues in	37
in the salivary glands	37
the control of the	37
a polymorphism in the	37
th or th responses	37
activation of interferon regulatory	37
and the subsequent development	37
to be deficient in	37
clinical data of the	37
the observed reduction of	37
were homozygous for the	37
be able to induce	37
alveolar epithelial cell line	37
of this study suggest	37
response to contact with	37
than in patients with	37
found to be activated	37
the subsequent activation of	37
necessary but not sufficient	37
chronic hepatitis b patients	37
with g ml of	37
migration of inflammatory cells	37
is incorporated into the	37
in the regional lymph	37
this study is that	37
the design of new	37
in agreement with the	37
of patients infected with	37
have a critical role	37
the effects of recombinant	37
the induction of antigen	37
the cytokine profile in	37
the proportion of the	37
a longitudinal study of	37
significantly more frequent in	37
high amounts of il	37
in cd t cells	37
of the patients with	37
both primary and secondary	37
during infection with the	37
to the response to	37
by fusion of the	37
class ii and cd	37
might be used to	37
preliminary results suggest that	37
in hepatitis c virus	37
for treatment of inflammatory	37
significant differences in the	37
and the costimulatory molecules	37
of human nk cells	37
of the patients presented	37
high levels of il	37
as a negative regulator	37
the analyses were performed	37
and the kinetics of	37
confocal laser scanning microscopy	37
in the effect of	37
the immune response through	37
of the two major	37
t cells from healthy	37
is a naturally occurring	37
in the lack of	37
due to the difference	37
was observed in animals	37
genes involved in lipid	37
pbmcs were incubated with	37
we used a mouse	37
genes involved in host	37
in response to contact	37
two members of the	37
did not affect the	37
indicate a role for	37
declare that they have	37
did not show any	37
large amounts of il	37
was determined by an	37
sequence similarity to the	37
likely to be involved	37
mediated by the induction	37
of house dust mite	37
phosphorylation and nuclear translocation	37
this is particularly important	37
but due to the	37
we investigated the ability	37
a crucial step in	37
may have important implications	37
molecules cd and cd	37
tissue from patients with	37
has a critical role	37
to cd t cells	37
it is shown that	37
but their role in	37
ebola virus vp protein	37
been shown to elicit	37
of c and c	37
are required in order	37
there is a potential	37
alternative activation of macrophages	37
used as a marker	37
with and without the	37
were determined in patients	36
as being involved in	36
recognition receptors of the	36
induce apoptotic cell death	36
t cells play an	36
incubated with mg ml	36
would like to thank	36
an association of the	36
activation of macrophages and	36
be activated by the	36
undertaken to investigate the	36
cellular immune responses were	36
may be a risk	36
have to be interpreted	36
a th phenotype and	36
modulation of innate and	36
characterized by flow cytometry	36
the cellular immune system	36
in patients with ae	36
of cd by cd	36
be noted that this	36
rna was isolated from	36
to an increase in	36
the lack of response	36
found to increase the	36
which in turn results	36
up to weeks post	36
may be contributing to	36
by flow cytometry after	36
requires the use of	36
innate immune responses and	36
cells and nk cells	36
from patients and healthy	36
of the inflammatory response	36
in part mediated by	36
in both primary and	36
million people worldwide and	36
not mediated by the	36
the interface of the	36
in response to foreign	36
seem to be involved	36
cells and endothelial cells	36
in healthy control subjects	36
cells have not been	36
may also inhibit the	36
the development of sle	36
igg and iga antibodies	36
cytotoxicity was measured by	36
was no difference in	36
costimulatory molecules cd and	36
expression of the other	36
shown to be deficient	36
disease of the central	36
most of the known	36
found in association with	36
effects on the host	36
the function of th	36
be used as a	36
are pattern recognition receptors	36
was performed as described	36
will allow us to	36
for the binding of	36
increased production of the	36
t cells of the	36
the cytokine production in	36
the context of the	36
sequences as well as	36
of classical swine fever	36
of the protective effect	36
in the serum of	36
including rheumatoid arthritis and	36
differences were found among	36
but only in the	36
biopsies of patients with	36
involvement in the pathogenesis	36
a multiplicity of infection	36
the cytometric bead array	36
with a molecular mass	36
association of single nucleotide	36
vero e cells were	36
in diabetic patients with	36
group and control groups	36
with those of other	36
and type iii ifn	36
induction of dc maturation	36
be contributing to the	36
of the control and	36
persisted for more than	36
well as in healthy	36
recent studies suggested that	36
coding regions of the	36
similar to the response	36
in response to e	36
can be stimulated by	36
on the role of	36
mucosal and systemic immunity	36
was undertaken to investigate	36
the absence of a	36
release of the pro	36
treatment did not induce	36
monoclonal antibody against the	36
this could lead to	36
of most of the	36
appears to be necessary	36
of the binding site	36
contributing to the severity	36
no production in macrophages	36
the production of all	36
of these genes are	36
t cells were monitored	36
in patients with sle	36
were detected in mice	36
compared to the group	36
of both mouse and	36
epitopes present in the	36
in sera of mice	36
both murine and human	36
and molecules involved in	36
experiments showed that the	36
of igg and iga	36
in the capacity to	36
between patients with and	36
was to define the	36
to the complexity of	36
effects of this cytokine	36
system is an important	36
pathway of innate immunity	36
were randomly selected for	36
a retrospective cohort study	36
we investigated whether il	36
mouse model of allergic	36
been demonstrated in several	36
were incubated with mg	36
to be interpreted with	36
similar in patients with	36
the host immune system	36
concentration was measured by	36
of human immunodeficiency virus	36
in the lung by	36
was to analyse the	36
ex vivo in the	36
study is that the	36
t cells for the	36
pathways are involved in	36
turn results in the	36
the nk cells and	36
to better understand the	36
assays for detection of	36
the capacity of different	36
a result of a	36
by these cells in	36
observed in the group	36
we now report that	36
grown in the presence	36
h n and h	36
gene expression profiles were	36
we also demonstrate that	36
study was designed to	36
be one of the	36
a murine model of	36
of t cells from	36
flow cytometry and confocal	36
the inhibition of the	36
b cells and the	36
has been on the	36
were performed using a	36
resulting in an increased	36
may play an important	36
seems not to be	36
more studies are required	36
have a lower risk	36
t cells are involved	36
the costimulatory molecules cd	36
supplemented with fetal bovine	36
the activation state of	36
synthetic peptides corresponding to	36
so that they are	36
in a parallel experiment	36
for the maturation of	36
were used to investigate	35
in a negative feedback	35
this interaction leads to	35
a molecular mass of	35
compared to the clinical	35
when compared to the	35
effect on cell proliferation	35
possible role of this	35
detected in mice immunized	35
in the association between	35
breast cancer cell line	35
macrophages are capable of	35
we show that ifn	35
studies will address whether	35
the effect of various	35
findings indicate that ifn	35
a profound impact on	35
from these studies will	35
that the amino acid	35
mrna expression was evaluated	35
various cancer cell lines	35
role for the human	35
of response to the	35
complement system is an	35
amino acid residues from	35
to find the optimal	35
cells from healthy volunteers	35
and without the addition	35
people worldwide and represents	35
of binding affinities of	35
in serum from patients	35
to the identification of	35
is considered as the	35
the onset of disease	35
a lower dose of	35
studies will also be	35
can be converted to	35
exist in dairy cows	35
was evaluated by real	35
data suggest that the	35
the upper respiratory tract	35
and the presentation of	35
a and c a	35
on various cancer cell	35
there is a distinct	35
igg antibodies in the	35
the balance between tolerance	35
apoptotic cells in the	35
of the other proteins	35
cells were cotransfected with	35
expression did not correlate	35
uptake of mbp by	35
the three proteins were	35
they also play an	35
sensitive detection in the	35
such as helicobacter pylori	35
used a mouse model	35
the presence and the	35
determined by an elisa	35
b cells may be	35
investigated the presence of	35
that the transcription factor	35
normal functions of the	35
the clinical data of	35
was used to determine	35
the results also indicated	35
levels for up to	35
on t cells in	35
play a role for	35
development of experimental autoimmune	35
with and without vascular	35
the presence of intact	35
difference when compared to	35
is associated with poorer	35
would be a possible	35
belonging to the b	35
interpreted with caution and	35
leads to increased susceptibility	35
increased in the gc	35
in both groups but	35
critical role in the	35
observed the production of	35
predisposition and environmental factors	35
located at the interface	35
we have recently generated	35
elicited by the same	35
infection in this group	35
this may provide a	35
the main difference between	35
with hepatitis b surface	35
the expression of a	35
suggest a possible role	35
effect of these cytokines	35
these cells were found	35
surface plasmon resonance analysis	35
the potential exists for	35
in peripheral blood at	35
investigate the association between	35
for the capacity of	35
gene in a patient	35
the presence of il	35
the salivary glands of	35
future studies will address	35
the solid support and	35
and type iii interferons	35
strains were tested for	35
as in the expression	35
respiratory syncytial virus and	35
content of the cell	35
mhc ii expression on	35
was found to give	35
have found that both	35
were stimulated with autologous	35
the presence of sera	35
the maturation marker cd	35
expanded t cells were	35
detected in out of	35
is a potential risk	35
following acute viral infection	35
responses in the spleen	35
in the upper airways	35
a type immune response	35
venezuelan equine encephalitis virus	35
leading to production of	35
diseases such as chronic	35
and the cytokine production	35
in this regard is	35
time of treatment was	35
may be achieved by	35
as detected by the	35
mice that lack both	35
were directed to the	35
cells was evaluated by	35
of these molecules to	35
been known to play	35
design of new vaccines	35
special emphasis on the	35
in the pathogenesis remains	35
the presence of igg	35
presence of sera from	35
the findings indicate that	35
marker cd and the	35
in the coding regions	35
we showed that recombinant	35
and clinical response to	35
paving the way for	35
indicated that suppression of	35
a suitable model for	35
with sequence similarity to	35
we have shown the	35
may account for their	35
used to identify patients	35
for cancer treatment in	35
by western blot analysis	35
of mice immunized with	35
the normal functions of	35
was associated with poor	35
the protein content of	35
the patients presented with	35
although the importance of	35
used to examine the	35
expression of cd by	35
by influenza a virus	35
correlated with a lower	35
we investigated the presence	35
control of cell cycle	35
lung function and symptoms	35
the safety and efficacy	35
to optimize the immune	35
carried out to find	35
important not only for	35
and is recognized by	35
attempt to find a	35
with a type immune	35
a similar effect of	35
demyelinating disease of the	35
which could be of	35
acute infection of mice	35
role for the development	35
in both patient groups	35
activated by proinflammatory cytokines	35
of how the immune	35
crucial step in the	35
the presence of cpg	35
immunogenicity and protection against	35
mediated by dendritic cells	35
makes it possible to	35
production of the inflammatory	35
are negative regulators of	35
has been applied to	35
at a lower dose	35
did not induce apoptotic	35
characterized by increased expression	35
when monocytes differentiate into	35
to levels comparable to	35
antibodies were present in	35
the pathogenesis of microvascular	35
human collectins in colorectal	35
asthma and allergic rhinitis	35
both lymphoid and nonlymphoid	35
may play a key	35
patients before and after	35
might be used for	35
at high levels for	35
role for b cells	35
results suggest that there	35
of apoptotic cells in	35
and surface plasmon resonance	35
pbmc in response to	35
of bronchial asthma and	35
the binding of dsrna	35
responses target the virus	35
has been postulated in	35
complement activity may be	35
during the initial phase	35
serum total ige levels	35
are important regulators of	35
and a set of	35
cytokine that is produced	35
maturation and production of	35
mount an inflammatory response	35
its ability to trigger	35
percentage of cells positive	35
the presence of type	35
suggest an involvement of	35
hematopoietic stem cell transplantation	35
resulting in the lack	35
and expression of genes	35
that protection was not	35
could not be observed	35
only the expression of	35
were investigated for their	35
not induce apoptotic cell	35
of lactic acid bacteria	35
out to find the	35
of responses target the	35
this means that the	35
were significantly downregulated in	35
performed using a leica	35
the acute infection of	35
the upper airways and	35
with two doses of	35
for their susceptibility to	35
are now in clinical	35
activity were observed in	35
immune response to the	35
cells were cultured from	35
the uptake of mbp	35
often decreases to a	35
that is incorporated into	35
was estimated in a	35
development of vaccines and	35
subsequent challenge with the	35
of no production in	35
did not change during	35
and c have been	35
have recently generated a	35
concentrations were significantly higher	35
which recognize molecular structures	35
which was not significantly	35
components like c q	35
by b cells and	35
analyzed by flow cytometry	35
this could serve as	35
in addition to suppressing	35
and the concentration in	35
production and stimulation of	35
surface mhc class ii	35
treated with acid and	35
were measured on day	35
indicate that the use	35
patients were treated with	35
the form of dna	35
similar in both patient	35
lymphoid and nonlymphoid cells	35
examined in this study	35
enhanced type i interferon	35
be promoted by the	35
proteins were developed and	35
not bind to any	35
igg antibodies were detected	35
we therefore examined the	35
we have used this	35
of different groups of	35
such as chronic inflammatory	35
stability of the virus	35
vast majority of the	35
minor salivary gland tissue	35
and fixed in paraformaldehyde	35
effect was observed for	35
while on the other	35
to bind to different	35
chronic inflammatory skin disease	35
to severe acute respiratory	35
were observed in the	35
binding of ospe to	35
were no significant differences	35
are responsible for the	35
genetic predisposition and environmental	35
results may have important	35
studies are required to	35
also indicated that the	35
t cells during the	35
protein content of the	35
cytokine response to gram	35
treatment of inflammatory diseases	35
the coding regions of	35
we have investigated how	35
using the commercially available	35
initial phase of the	35
the proliferative response was	35
ospe to the c	35
of the lcm virus	35
balance between tolerance and	35
of ospe to the	35
on natural killer cell	35
of the pbmcs was	35
these results show that	35
were significantly more frequent	35
prove to be an	35
killer cell cytotoxicity and	35
work in our lab	35
has been suggested to	35
in high levels of	35
study was to define	35
no major role for	35
appeared to be more	35
and control groups was	35
more frequent in diabetic	35
on lung function and	35
autoantibodies in healthy individuals	35
the formation of complement	35
and their ligands are	35
to be more pronounced	35
appears to be limited	35
cell proliferation was not	35
be interesting to see	35
the binding site for	35
one by one in	35
compared using the mann	35
levels are elevated in	35
blood donors were cultured	35
seems to contribute to	35
cellular immune responses following	35
this is independent of	35
is located at the	35
cell cytotoxicity was measured	35
activity and disease severity	35
was numerically higher in	35
we analysed the data	35
we have also evaluated	35
complement components like c	35
we have conducted a	35
were found among the	35
screened for the presence	35
results in increased cell	35
amounts of nitric oxide	35
cells at all times	35
natural killer cell functions	35
the present study evaluated	35
is part of our	35
been shown to differ	35
dose in the range	35
the tnf production in	35
and decreases in the	35
had significantly elevated mbl	34
without mala s for	34
infection may play a	34
allow for a greater	34
found mainly in the	34
complement on phagocytosis of	34
without iga protease activity	34
is increased in cd	34
thereby becoming unresponsive to	34
regulators of genes involved	34
the integrity of iga	34
higher risk of leukaemia	34
a few scattered proliferating	34
identify the tlr involved	34
due to the reported	34
may lead to the	34
if asthma was controlled	34
fourfold higher opsonophagocytosis titer	34
when a more specific	34
as chronic inflammatory bowel	34
the selected ncoder framework	34
included sera from patients	34
we observed that lysines	34
for mapping of the	34
are surprisingly narrow in	34
differently from the wt	34
for further characterization of	34
gc have a higher	34
they can promote cell	34
blood drawn from eight	34
was significantly higher after	34
tested for induction of	34
h binding to ospe	34
the adjuvant potential of	34
primes for a th	34
that species of lactic	34
fusion protein induced a	34
epitopes were removed one	34
recently generated a human	34
our lab has demonstrated	34
variants of streptococcus pneumonia	34
of ae is not	34
direct measurenment of the	34
data suggest that prevalence	34
samples were obtained sequentially	34
homologous wildtype target bacteria	34
related molecules as being	34
expression without simultaneous upregulation	34
dna vaccine coding for	34
of piglets throughout the	34
to stimulate expression of	34
and macrovascular complications in	34
significant pathology and long	34
stimulator of interferon genes	34
by both lymphoid and	34
and ionic interactions are	34
safer alternative for specific	34
proinflammatory cytokine tumour necrosis	34
been found to predispose	34
the concentration in plasma	34
animals were also exposed	34
surface expression of toll	34
at position showed increased	34
protease activity and complement	34
mala s on antigen	34
and denaturing gradient gel	34
potentiated the cytokine response	34
the cell by binding	34
in der p and	34
of sows fed the	34
the malarial antigen fused	34
a whole blood stimulation	34
well as igg caga	34
standard assays for detection	34
upper airways and circulation	34
to ingest iga antibody	34
degradation processes of antigens	34
demonstrated in other autoimmune	34
purified monocytes and monocyte	34
with allergic rhinitis and	34
the relation of h	34
proliferation may be attributed	34
incidence is even higher	34
nab against the ifn	34
inflammatory response to gram	34
of asthma and allergic	34
healthy controls as well	34
t cells that recognize	34
indicating that this oral	34
cell cytotoxicity and subsets	34
peptides spanning over the	34
human phagocytic cell line	34
immunospot to overlapping peptides	34
decreases to a critical	34
monocytes differentiate into dcs	34
increased the binding efficiency	34
the cysteine protease der	34
transduction and expression of	34
served as control donors	34
ms from stockholm was	34
analysed using standard statistical	34
in distribution and remain	34
sendai virus from inducing	34
cell line in the	34
atmosphere outside the pressurized	34
is in agreement with	34
animals exhibited considerable less	34
level in persons working	34
more pronounced in wells	34
resulting in anaphylactic reactions	34
was obtained by fusion	34
expression occurs via a	34
in atopics and patients	34
regions of ospe were	34
b cells from human	34
patients and normal mucosa	34
the synthesis of leukotriene	34
could be of value	34
directly designed for protein	34
transcription of the novel	34
ae assessed in clinical	34
some variation in the	34
whereas sendai virus utilizes	34
igm in serum of	34
analysis of thousands of	34
level of vitamin e	34
as tnf and ifn	34
samples were determined and	34
diffusion and affinity coupling	34
to a critical low	34
could directly interact with	34
flora is crucial for	34
crc patients and normal	34
were successfully applied as	34
majority of the cd	34
and symptoms at clinic	34
priming effect was observed	34
than in patients receiving	34
of complement factor c	34
dm and healthy controls	34
this protease in standard	34
cells to investigate the	34
not believed to play	34
who received peripheral blood	34
nephropathy and t dm	34
activation of proteases like	34
polarize differentially dc maturation	34
pneumococci produce iga protease	34
that suppression of kb	34
in peptides spanning over	34
when analysed by flow	34
frequency of proliferating cells	34
microdissected and rna isolated	34
pneumococci by an unstimulated	34
working in normobar atmosphere	34
present study evaluated the	34
samples were collected seven	34
stability and arrayed dehydrated	34
weeks fed either a	34
the capacity to activate	34
the whole lymph node	34
risk of developing these	34
of high mbl genotypes	34
lipoproteins during mammalian infection	34
whereas ldh release by	34
to eliminate the noncytopathic	34
bacteria than in wells	34
the interaction between vitamin	34
of concentration by active	34
single amino acid residues	34
dc to lethally irradiated	34
in these studies indicated	34
total am concentration of	34
than achieved by ics	34
was used to sensitize	34
the protozoan trypanosoma brucei	34
was significantly lower in	34
allergic individuals are reactive	34
to understand the relation	34
tick vector into the	34
levels and complement activity	34
with specific primers for	34
of responses were directed	34
vitamins e and c	34
findings suggest that mbl	34
due to the complexity	34
different antigens of a	34
sensitive to complement killing	34
effects observed after bmt	34
at a higher level	34
with clinical gvhd could	34
and cd were upregulated	34
phenotype and mt with	34
the mbl gene in	34
for factor h interactions	34
of the host cell	34
the protein microarray technology	34
stockholm but not from	34
of mbl status might	34
of hsp primes for	34
inhibitory and stimulatory effect	34
ldh release by these	34
key lysine residues in	34
that parts of the	34
we conclude that most	34
of an otherwise lethal	34
modulate cancer cell proliferation	34
to respond to different	34
vitamin e status of	34
complications were driven primarily	34
b infection are surprisingly	34
clinical signs of arthritis	34
we aim to develop	34
measurenment of the proteins	34
be used for treatment	34
of pbmc estimated in	34
was below the noise	34
a multivariate regression model	34
and polymorphisms in the	34
these molecules to bind	34
responsiveness ex vivo to	34
as well as igg	34
mddcs exposed to mala	34
mucosa samples were collected	34
pylori as well as	34
recognized by both mbl	34
technique involving b cells	34
not any of the	34
of the tigr strain	34
maturation marker cd and	34
to obtain nearly pure	34
denaturing gradient gel electrophoresis	34
expression on splenocytes early	34
at least months by	34
find the optimal stimulation	34
the immune response revealed	34
addition to suppressing the	34
ligands are negative regulators	34
requirement for different tlr	34
compared to other days	34
able to ingest iga	34
the eicosanoid synthesis by	34
response to the capsid	34
although the cytotoxicity increased	34
cancer treatment in the	34
improved the immune responses	34
a g in exon	34
memory response of virus	34
as the cytolytic activity	34
required for factor h	34
activity and complement on	34
patients with regular focal	34
ospe were required for	34
in the phagocytotic uptake	34
revealed that the c	34
cytokines in culture supernatants	34
after weaning compared to	34
persistent normoalbuminuria matched for	34
phenotype may be associated	34
interesting due to the	34
ifn and decreases in	34
for microarrays providing sensitive	34
a detailed status of	34
reflect the stress level	34
currently investigating the cellular	34
a material of haematoxylin	34
these cytokines and this	34
increase the cellular and	34
experiments with rmbl partially	34
and analysed for the	34
part of our normal	34
mbp by b cells	34
and natural autoantibodies in	34
immununized mice that lack	34
tlr on dcs was	34
have addressed the issues	34
peptides restricted to the	34
both inhibitory and stimulatory	34
of the nk cells	34
strains of lactobacillus spp	34
an unknown cofactor increase	34
they are suitable for	34
to examine the cytokine	34
an effective method for	34
conclude that most proliferating	34
genus dermatophagoides pteronyssinus is	34
it of hdm allergy	34
cells and platelets were	34
was found to express	34
transcriptional regulators of genes	34
the a cell line	34
c but not c	34
antigen fused with a	34
the iga protease activity	34
monocytes produced higher levels	34
to the virus nonstructural	34
both probes and solid	34
it suitable for mapping	34
and auricular lymph nodes	34
of the target bacteria	34
tissue was microdissected and	34
expression of factor h	34
the identification of such	34
frequencies of apoptotic cells	34
of divers compared to	34
the capability of ms	34
an involvement of the	34
frequent in diabetic patients	34
elicit specific ige and	34
dramatically increased humoural responses	34
mice were killed at	34
auricular lymph nodes were	34
the more stabile physiological	34
seroimmunological phenotype and warrant	34
which were threefold higher	34
strategies for our microarray	34
burgdorferi is due to	34
a potential risk of	34
studied whether vitamin c	34
to different commensal bacteria	34
patients presented with anti	34
were stimulated with il	34
regression in nude mice	34
are dramatically induced by	34
drawn from eight divers	34
regional lymph nodes demonstrated	34
associated with poor survival	34
to the reported sparing	34
shift to a cd	34
these t cells in	34
the balance between these	34
sensitivity in the oral	34
to certain colorectal carcinoma	34
a r or dominant	34
cells circulating in peripheral	34
significantly elevated mbl levels	34
in patients with end	34
stem cell grafts after	34
molecules expressed by vascular	34
the nuclear receptor heterodimers	34
but increased cd expression	34
profiles were analysed using	34
increase in cytotoxicity observed	34
diet supplemented with mg	34
to regulate mucosal and	34
was supported by the	34
collectins in colorectal cancer	34
sera to promote the	34
and may thus affect	34
mhc i molecules are	34
mbl binds to noncapsulated	34
be modulated according to	34
an increased risk of	34
by an unstimulated human	34
thereby allowing nonpurified probes	34
tested positive for iga	34
in silico epitope mapping	34
these cytokines are being	34
that lack both mbl	34
is dependent on interleukin	34
with pss was morphologically	34
exacerbation may associate with	34
that lysines in the	34
other clonotypes emerged during	34
on dcs and also	34
percent eosinophilia and percent	34
be stimulated by inflammatory	34
thus be target for	34
proteins on a single	34
study had both inhibitory	34
showed a significant expression	34
similar effect of iga	34
maintaining its ability to	34
are characterized by increased	34
found that mbl binds	34
a cell line is	34
frequently in the whole	34