This is a table of type quadgram and their frequencies. Use it to search & browse the list to learn more about your study carrel.
quadgram | frequency |
---|---|
porcine epidemic diarrhea virus | 2208 |
of porcine epidemic diarrhea | 1105 |
epidemic diarrhea virus in | 321 |
porcine epidemic diarrhoea virus | 277 |
in the united states | 244 |
severe acute respiratory syndrome | 157 |
epidemic diarrhea virus infection | 140 |
porcine reproductive and respiratory | 134 |
reproductive and respiratory syndrome | 133 |
for the detection of | 129 |
in the presence of | 127 |
the porcine epidemic diarrhea | 125 |
epidemic diarrhea virus strains | 125 |
acute respiratory syndrome coronavirus | 119 |
of the porcine epidemic | 119 |
porcine epidemic diarrhea viruses | 119 |
and respiratory syndrome virus | 119 |
of porcine epidemic diarrhoea | 118 |
porcine epidemic diarrhea in | 115 |
of the s protein | 109 |
complete genome sequence of | 106 |
epidemic diarrhea virus strain | 104 |
in the present study | 93 |
epidemic diarrhea virus and | 86 |
detection of porcine epidemic | 83 |
diarrhea virus in the | 81 |
emergence of porcine epidemic | 81 |
as shown in fig | 78 |
strain of porcine epidemic | 75 |
associated with diarrhea in | 73 |
characterization of porcine epidemic | 70 |
virus in the united | 70 |
and phylogenetic analysis of | 68 |
us porcine epidemic diarrhea | 67 |
isolation and characterization of | 66 |
with diarrhea in swine | 66 |
transmissible gastroenteritis virus and | 65 |
the results showed that | 63 |
review of molecular epidemiology | 63 |
sequence analysis of the | 63 |
a comprehensive review of | 62 |
comprehensive review of molecular | 62 |
the pedv s protein | 62 |
particle associated with diarrhea | 62 |
genome sequence of a | 61 |
and viral genomic sequences | 61 |
like particle associated with | 60 |
gene of porcine epidemic | 60 |
and porcine epidemic diarrhea | 59 |
used in this study | 59 |
gastroenteritis virus and porcine | 59 |
an important role in | 59 |
the end of the | 59 |
cells were infected with | 58 |
of transmissible gastroenteritis virus | 57 |
washed three times with | 56 |
of the s gene | 56 |
genes of porcine epidemic | 55 |
variants of porcine epidemic | 55 |
were infected with pedv | 55 |
phylogenetic analysis of porcine | 54 |
for porcine epidemic diarrhea | 54 |
against porcine epidemic diarrhea | 53 |
diarrhea virus in china | 53 |
in the s gene | 53 |
the s protein of | 53 |
on the other hand | 52 |
as shown in figure | 52 |
with porcine epidemic diarrhea | 52 |
epidemic diarrhea virus spike | 51 |
analysis of porcine epidemic | 51 |
samples were collected from | 50 |
new variants of porcine | 50 |
outbreak of porcine epidemic | 49 |
o u r n | 49 |
u r n a | 49 |
j o u r | 49 |
r n a l | 49 |
virus and porcine epidemic | 49 |
r o o f | 48 |
cells were transfected with | 48 |
a l p r | 48 |
p r o o | 48 |
the cells were washed | 48 |
l p r e | 48 |
was used as a | 48 |
n a l p | 48 |
cells were treated with | 48 |
in the spike gene | 47 |
diarrhea virus spike protein | 47 |
in vero e cells | 46 |
the presence of pedv | 46 |
the detection of pedv | 46 |
a member of the | 45 |
epidemic diarrhea virus from | 44 |
in the small intestine | 44 |
of pedv in the | 44 |
rna was extracted from | 44 |
of severe acute respiratory | 44 |
cells were incubated with | 42 |
and characterization of porcine | 42 |
variant porcine epidemic diarrhea | 42 |
as well as the | 42 |
in the absence of | 42 |
of the spike protein | 42 |
attenuated porcine epidemic diarrhea | 42 |
at the end of | 41 |
the authors declare that | 41 |
pigs of all ages | 41 |
of the small intestine | 41 |
virus strains in the | 41 |
aminopeptidase n is a | 41 |
genotyping of emergent porcine | 40 |
of emergent porcine epidemic | 40 |
strains in the united | 40 |
the detection of porcine | 40 |
propagation of the virus | 40 |
and genotyping of emergent | 40 |
characterization and phylogenetic analysis | 39 |
molecular characterization and phylogenetic | 39 |
strain pc a in | 39 |
african green monkey kidney | 39 |
diarrhea viruses associated with | 39 |
a porcine epidemic diarrhea | 39 |
epidemic diarrhea viruses associated | 39 |
emergent porcine epidemic diarrhea | 39 |
on the surface of | 39 |
were observed in the | 39 |
diarrhea virus strains in | 39 |
cells were fixed with | 39 |
and transmissible gastroenteritis virus | 39 |
were washed three times | 39 |
incubated for h at | 39 |
by porcine epidemic diarrhea | 38 |
evolution of pedv strains | 38 |
porcine epidemic diarrhea coronavirus | 38 |
of porcine reproductive and | 38 |
to porcine epidemic diarrhea | 38 |
of us porcine epidemic | 37 |
viruses associated with the | 37 |
the virus of porcine | 37 |
and complex evolution of | 37 |
of the virus of | 37 |
economic losses to the | 37 |
virus strain pc a | 37 |
diarrhea in suckling piglets | 37 |
in the s protein | 37 |
virus of porcine epidemic | 37 |
experimental infection of pigs | 37 |
min at room temperature | 37 |
complex evolution of pedv | 37 |
with fetal bovine serum | 37 |
characteristics and complex evolution | 36 |
for min at room | 36 |
swine in the united | 36 |
the gene source of | 36 |
middle east respiratory syndrome | 36 |
diarrhea virus strain pc | 36 |
associated with the disease | 36 |
porcine transmissible gastroenteritis virus | 36 |
strains of porcine epidemic | 36 |
for the presence of | 36 |
diarrhea in cell culture | 36 |
distinct characteristics and complex | 36 |
epidemic diarrhea in cell | 36 |
with the disease outbreak | 36 |
epidemic diarrhea in suckling | 35 |
disease outbreak among swine | 35 |
the porcine epidemic diarrhoea | 35 |
among swine in the | 35 |
outbreak among swine in | 35 |
the disease outbreak among | 35 |
has been shown to | 34 |
as the gene source | 34 |
was added to each | 34 |
coronaviruses as the gene | 34 |
care and use committee | 34 |
for the first time | 34 |
total rna was extracted | 34 |
animal care and use | 34 |
pensaert and de bouck | 33 |
added to each well | 33 |
and sequence analysis of | 33 |
adapted porcine epidemic diarrhea | 33 |
the spike gene of | 33 |
diarrhea viruses isolated in | 33 |
protein genes of porcine | 33 |
three times with pbs | 33 |
that they have no | 33 |
on the cell surface | 33 |
for the development of | 33 |
epidemic diarrhea viruses isolated | 33 |
of a porcine epidemic | 33 |
the s gene of | 33 |
variant of porcine epidemic | 32 |
hek t cells were | 32 |
the pedv n protein | 32 |
plays an important role | 32 |
declare that they have | 32 |
results showed that the | 32 |
authors declare that they | 32 |
vero e cells were | 32 |
play a role in | 31 |
cells were seeded in | 31 |
institutional animal care and | 31 |
a new porcine enteric | 31 |
was added to the | 31 |
a functional receptor for | 31 |
were detected in the | 31 |
pc a in gnotobiotic | 31 |
cells were inoculated with | 31 |
east respiratory syndrome coronavirus | 31 |
this is the first | 31 |
was used as the | 31 |
new porcine enteric coronavirus | 31 |
pcd and vero cells | 30 |
infected with pedv at | 30 |
and vero cells were | 30 |
the spike protein of | 30 |
large deletion in the | 30 |
spike gene of porcine | 30 |
the antiviral activity of | 30 |
of this study was | 30 |
similar to that of | 30 |
like strain of porcine | 30 |
pathology of us porcine | 30 |
studies have shown that | 30 |
porcine aminopeptidase n is | 30 |
isolation of porcine epidemic | 30 |
on the basis of | 30 |
supplemented with fetal bovine | 30 |
a in gnotobiotic pigs | 30 |
viruses isolated in korea | 30 |
was found to be | 29 |
on porcine epidemic diarrhea | 29 |
infected with porcine epidemic | 29 |
the intracellular extracts of | 29 |
for min at rt | 29 |
a variant porcine epidemic | 29 |
the s protein is | 29 |
was first reported in | 29 |
the severe acute respiratory | 29 |
for h and then | 29 |
the small intestine of | 29 |
s protein of pedv | 29 |
amino acid sequences of | 29 |
the recombinant s protein | 28 |
a large deletion in | 28 |
and the cells were | 28 |
with a large deletion | 28 |
the nucleocapsid protein of | 28 |
these results indicated that | 28 |
the sensitivity of the | 28 |
this work was supported | 28 |
in pigs of all | 28 |
this study was to | 28 |
a multiplicity of infection | 28 |
at room temperature for | 28 |
functional receptor for the | 28 |
the presence of trypsin | 28 |
new variant of porcine | 28 |
gds and gds strains | 28 |
the results of the | 28 |
of the orf gene | 28 |
epidemic diarrhoea virus in | 28 |
a and icpc a | 27 |
pigs with a new | 27 |
as a negative control | 27 |
cells were washed with | 27 |
antibodies against porcine epidemic | 27 |
at an moi of | 27 |
with a new porcine | 27 |
work was supported by | 27 |
in vitro and in | 27 |
infection of pigs with | 27 |
type i ifn production | 27 |
virus and transmissible gastroenteritis | 27 |
of pigs with a | 27 |
is a functional receptor | 27 |
these results indicate that | 27 |
and characterization of a | 27 |
the s and s | 27 |
icpc a and icpc | 27 |
the expression levels of | 26 |
were incubated for h | 26 |
detection and quantification of | 26 |
it is possible that | 26 |
of tbk and irf | 26 |
was detected in the | 26 |
feline infectious peritonitis virus | 26 |
neutralizing antibodies against the | 26 |
the cells were fixed | 26 |
of a variant porcine | 26 |
in the natural host | 26 |
cells infected with pedv | 26 |
is one of the | 26 |
in the current study | 26 |
to the swine industry | 26 |
they have no competing | 26 |
in accordance with the | 26 |
classical attenuated vaccine strains | 26 |
outbreaks of porcine epidemic | 26 |
porcine intestinal epithelial cells | 25 |
phylogenetic analysis based on | 25 |
detection of antibodies against | 25 |
of transmissible gastroenteritis coronavirus | 25 |
phylogenetic analysis of the | 25 |
of the nucleocapsid protein | 25 |
play an important role | 25 |
and the united states | 25 |
region capable of inducing | 25 |
of inducing neutralizing antibodies | 25 |
sequence of a porcine | 25 |
then infected with pedv | 25 |
at a concentration of | 25 |
these results suggest that | 25 |
vero cells were infected | 25 |
deletion in the spike | 25 |
vitro and in vivo | 25 |
molecular evolutionary genetics analysis | 25 |
against the porcine epidemic | 25 |
similar to those of | 25 |
cd cd t cell | 25 |
well tissue culture plates | 25 |
of pedv rna in | 25 |
than that of the | 25 |
of the pedv s | 25 |
restriction fragment length polymorphism | 25 |
we found that the | 25 |
the amino acid sequence | 24 |
the united states and | 24 |
korean pedv field isolates | 24 |
complete genome sequences of | 24 |
like particles associated with | 24 |
presence or absence of | 24 |
inducing neutralizing antibodies against | 24 |
the detection limit of | 24 |
cells were cultured in | 24 |
the jejunum and ileum | 24 |
protein of porcine epidemic | 24 |
of pedv n protein | 24 |
have no competing interests | 24 |
and then infected with | 24 |
antibodies against the porcine | 24 |
cell culture isolation and | 24 |
the pedv spike protein | 24 |
capable of inducing neutralizing | 24 |
the united states porcine | 24 |
at the same time | 23 |
genome sequence of porcine | 23 |
one of the most | 23 |
epitope region capable of | 23 |
emerging epizootic swine virus | 23 |
with paraformaldehyde for min | 23 |
type i interferon production | 23 |
identification of the epitope | 23 |
the cells were then | 23 |
an emerging and re | 23 |
cells were grown in | 23 |
caused by porcine epidemic | 23 |
no conflict of interest | 23 |
the epitope region capable | 23 |
was significantly higher than | 23 |
in this study were | 23 |
the presence of the | 23 |
propagated in vero cells | 23 |
of prrsv and pedv | 23 |
economic losses in the | 23 |
is a member of | 23 |
of the epitope region | 23 |
the gds and gds | 23 |
with porcine epidemic diarrhoea | 23 |
at a multiplicity of | 23 |
an outbreak of swine | 23 |
for the simultaneous detection | 23 |
g a and g | 23 |
china complete genome sequence | 22 |
to that of the | 22 |
of a vero cell | 22 |
or s t protein | 22 |
important role in the | 22 |
epithelial cells of the | 22 |
results indicated that the | 22 |
of the n gene | 22 |
as a result of | 22 |
epidemic diarrhea virus date | 22 |
were significantly higher than | 22 |
were fixed with paraformaldehyde | 22 |
the heat and rnase | 22 |
heat and rnase treated | 22 |
novel porcine epidemic diarrhea | 22 |
the innate immune response | 22 |
the cells were collected | 22 |
a final concentration of | 22 |
syndrome of porcine epidemic | 22 |
new syndrome of porcine | 22 |
like particles in japan | 22 |
g for min at | 22 |
united states porcine epidemic | 22 |
can be divided into | 22 |
sialic acid binding activity | 22 |
were positive for pedv | 22 |
the cells were incubated | 21 |
and porcine respiratory coronavirus | 21 |
the vero cells and | 21 |
deduced amino acid sequences | 21 |
strain with a large | 21 |
the orf gene of | 21 |
the partial s gene | 21 |
at the time of | 21 |
pcr and western blotting | 21 |
the first time in | 21 |
strains similar to us | 21 |
n is a functional | 21 |
virus strains similar to | 21 |
and high mortality in | 21 |
receptor for the pedv | 21 |
for the pedv coronavirus | 21 |
in the cytoplasm of | 21 |
at different time points | 21 |
the authors declare no | 21 |
were negative for pedv | 21 |
spread of porcine epidemic | 21 |
similar to us strains | 21 |
s domain of the | 21 |
based on the s | 21 |
the ohio state university | 21 |
the n gene of | 21 |
growth adaptation in vitro | 21 |
an intact s gene | 21 |
diarrhea virus strains similar | 21 |
are listed in table | 21 |
genetically diverse us porcine | 20 |
the expression of the | 20 |
morbidity and mortality in | 20 |
pedv s or s | 20 |
of swine diarrhea of | 20 |
culture isolation and sequence | 20 |
related porcine epidemic diarrhea | 20 |
epidemiology of porcine epidemic | 20 |
epidemic diarrhea in canada | 20 |
vero cells were seeded | 20 |
of tgev and pedv | 20 |
virus strains including a | 20 |
a and orf b | 20 |
at c for h | 20 |
analysis of genetically diverse | 20 |
novel strain with a | 20 |
s or s t | 20 |
tissue culture infectious dose | 20 |
isolation and sequence analysis | 20 |
diarrhea virus strains including | 20 |
sequence analysis of genetically | 20 |
including a novel strain | 20 |
be due to the | 20 |
porcine apn transgenic mice | 20 |
of pedv pl pro | 20 |
completion of the porcine | 20 |
of the virus in | 20 |
fixed with paraformaldehyde for | 20 |
approved the final manuscript | 20 |
in the presence or | 20 |
the plates were incubated | 20 |
an apparently new syndrome | 20 |
and approved the final | 20 |
cell adapted porcine epidemic | 20 |
a novel strain with | 20 |
our results showed that | 20 |
porcine group a rotavirus | 20 |
apparently new syndrome of | 20 |
the positive control group | 20 |
analysis was performed using | 20 |
cells were pretreated with | 20 |
epidemic diarrhea virus by | 20 |
fragment length polymorphism analysis | 20 |
outbreak of swine diarrhea | 20 |
of genetically diverse us | 20 |
swine diarrhea of a | 20 |
with bovine serum albumin | 20 |
strains including a novel | 20 |
the small and large | 20 |
the united states in | 20 |
shown in figure a | 19 |
the presence or absence | 19 |
polymorphism analysis of orf | 19 |
as shown in table | 19 |
from korean field strains | 19 |
was observed in the | 19 |
spike protein is a | 19 |
statistical analysis was performed | 19 |
it has been reported | 19 |
vero cells were grown | 19 |
length polymorphism analysis of | 19 |
current epidemiology and available | 19 |
type associated with coronavirus | 19 |
simultaneous detection and quantification | 19 |
epidemic diarrhea virus dr | 19 |
nucleotide and amino acid | 19 |
pedv in vero cells | 19 |
to transmissible gastroenteritis virus | 19 |
nucleotide sequences of the | 19 |
diarrhea virus from korean | 19 |
of current epidemiology and | 19 |
used as a negative | 19 |
a vero cell adapted | 19 |
porcine epidemic diarrhoea coronavirus | 19 |
orf a and orf | 19 |
differentiation of a vero | 19 |
of mouse hepatitis virus | 19 |
epidemiology and available vaccines | 19 |
molecular epidemiology of porcine | 19 |
strains by restriction fragment | 19 |
of attenuated porcine epidemic | 19 |
entry of porcine epidemic | 19 |
the negative control group | 19 |
mortality in neonatal piglets | 19 |
domain of the porcine | 19 |
epidemic diarrhea virus field | 19 |
a review of current | 19 |
member of the genus | 19 |
by restriction fragment length | 19 |
lower than that of | 19 |
at a moi of | 19 |
read and approved the | 19 |
pcr for the simultaneous | 19 |
review of current epidemiology | 19 |
of alphacoronavirus and betacoronavirus | 19 |
epidemic diarrhoea virus and | 19 |
diverse us porcine epidemic | 19 |
analysis based on the | 19 |
as seen in figure | 19 |
host innate immune response | 19 |
virus from korean field | 19 |
of the spike gene | 19 |
suckling and weaned pigs | 19 |
epidemic diarrhea virus porcine | 19 |
the simultaneous detection and | 19 |
korean field strains by | 19 |
the causative agent of | 19 |
sequence of porcine epidemic | 19 |
de arriba et al | 19 |
vero cell adapted porcine | 19 |
field strains by restriction | 19 |
from three independent experiments | 19 |
the duration of the | 18 |
to jurisdictional claims in | 18 |
of global porcine epidemic | 18 |
nature remains neutral with | 18 |
spike protein genes of | 18 |
claims in published maps | 18 |
diarrhea virus in south | 18 |
springer nature remains neutral | 18 |
of blfp crude extract | 18 |
intracellular extracts of ln | 18 |
been shown to be | 18 |
of type i interferon | 18 |
the complete genome sequences | 18 |
and attenuation of virulence | 18 |
the new ica was | 18 |
an ion channel protein | 18 |
epidemic diarrhea viruses from | 18 |
is the first report | 18 |
in published maps and | 18 |
of the genus alphacoronavirus | 18 |
adaptation in vitro and | 18 |
and serial propagation of | 18 |
attenuation of virulence in | 18 |
in spike protein genes | 18 |
diarrhea virus in porcine | 18 |
maps and institutional affiliations | 18 |
of virulence in vivo | 18 |
global porcine epidemic diarrhea | 18 |
rna was detected in | 18 |
isolation and serial propagation | 18 |
of type i ifn | 18 |
we found that pedv | 18 |
there were no significant | 18 |
h at room temperature | 18 |
were similar to those | 18 |
plates were incubated for | 18 |
in the swine industry | 18 |
with regard to jurisdictional | 18 |
positive cells in the | 18 |
jurisdictional claims in published | 18 |
were considered statistically significant | 18 |
s gene of pedv | 18 |
was performed as described | 18 |
from the united states | 18 |
the host innate immune | 18 |
were found to be | 18 |
the specificity of the | 18 |
published maps and institutional | 18 |
the replication of pedv | 18 |
and functional characterization of | 18 |
identified in this study | 18 |
virus porcine epidemic diarrhea | 18 |
with growth adaptation in | 18 |
regard to jurisdictional claims | 18 |
the coronavirus spike protein | 18 |
were washed with pbs | 18 |
higher than that of | 18 |
in cell cultures and | 18 |
and incubated for h | 18 |
for h at room | 18 |
losses to the swine | 18 |
mortality in suckling piglets | 18 |
in the small intestines | 18 |
it has been shown | 18 |
results suggest that the | 18 |
in the family coronaviridae | 18 |
heterogeneity in spike protein | 18 |
and partial characterization of | 18 |
vero cells were inoculated | 18 |
spike glycoprotein gene of | 18 |
as a vehicle for | 18 |
the pcr products were | 18 |
remains neutral with regard | 18 |
neutral with regard to | 18 |
with transmissible gastroenteritis virus | 18 |
as a cause of | 18 |
comparison of porcine epidemic | 17 |
cultures and partial characterization | 17 |
infected vero e cells | 17 |
analysis of the orf | 17 |
from germany and the | 17 |
in this study are | 17 |
novel mammalian and avian | 17 |
blocked with bovine serum | 17 |
structural and functional characterization | 17 |
seven novel mammalian and | 17 |
could be detected in | 17 |
the n protein of | 17 |
and avian coronaviruses in | 17 |
in vitro and attenuation | 17 |
cell cultures and partial | 17 |
cell attenuated porcine epidemic | 17 |
vitro and attenuation of | 17 |
and avian coronaviruses as | 17 |
in porcine intestinal epithelial | 17 |
analysis of the spike | 17 |
sequences of the s | 17 |
mammalian and avian coronaviruses | 17 |
encodes an ion channel | 17 |
cells in the small | 17 |
supports bat coronaviruses as | 17 |
pigs porcine epidemic diarrhea | 17 |
were collected from the | 17 |
the survival of pedv | 17 |
partial characterization of the | 17 |
is a class i | 17 |
germany and the united | 17 |
of gammacoronavirus and deltacoronavirus | 17 |
diarrhoea virus in italy | 17 |
in the pathogenesis of | 17 |
the nucleotide sequences of | 17 |
diarrhea of a new | 17 |
was used for the | 17 |
mutations in the spike | 17 |
alphacoronavirus and betacoronavirus and | 17 |
quantification of transmissible gastroenteritis | 17 |
fecal samples were collected | 17 |
class i virus fusion | 17 |
by porcine epidemic diarrhoea | 17 |
induction of neutralizing antibodies | 17 |
coronavirus spike protein is | 17 |
associated with porcine epidemic | 17 |
cloning and further sequence | 17 |
in significant economic losses | 17 |
viruses from germany and | 17 |
source of alphacoronavirus and | 17 |
discovery of seven novel | 17 |
virus in cell cultures | 17 |
at rt for min | 17 |
were no significant differences | 17 |
avian coronaviruses as the | 17 |
no significant differences in | 17 |
for the detection and | 17 |
in the vero cells | 17 |
were orally inoculated with | 17 |
onset of clinical signs | 17 |
source of gammacoronavirus and | 17 |
and s t proteins | 17 |
cells were washed three | 17 |
the aim of this | 17 |
and quantification of transmissible | 17 |
characterization of the isolate | 17 |
diarrhea virus strain from | 17 |
for the duration of | 17 |
bat coronaviruses as the | 17 |
in addition to the | 17 |
gene source of gammacoronavirus | 17 |
was kindly provided by | 17 |
detection limit of the | 17 |
vaccines for porcine epidemic | 17 |
aim of this study | 17 |
gene source of alphacoronavirus | 17 |
to those of the | 17 |
betacoronavirus and avian coronaviruses | 17 |
with different concentrations of | 17 |
analysis of the partial | 17 |
significantly higher than the | 17 |
of seven novel mammalian | 17 |
epidemic diarrhea virus nucleocapsid | 17 |
further sequence analysis of | 17 |
propagation of porcine epidemic | 17 |
in serum and colostrum | 17 |
and betacoronavirus and avian | 17 |
associated with growth adaptation | 17 |
type i and type | 17 |
authors read and approved | 17 |
detection of transmissible gastroenteritis | 17 |
the early stage of | 17 |
these data indicate that | 17 |
deltacoronavirus supports bat coronaviruses | 17 |
and further sequence analysis | 17 |
the development of a | 16 |
high morbidity and mortality | 16 |
the complete genome sequence | 16 |
in swine porcine epidemic | 16 |
a class i virus | 16 |
the mesenteric lymph nodes | 16 |
epidemic diarrhea virus isolate | 16 |
pedv rna was detected | 16 |
until the end of | 16 |
epidemic diarrhea virus genome | 16 |
vero cells and ipec | 16 |
mutations in the s | 16 |
in the genus deltacoronavirus | 16 |
study was to determine | 16 |
i virus fusion protein | 16 |
of the new ica | 16 |
with an intact s | 16 |
the fusion core complex | 16 |
of the order nidovirales | 16 |
performed as described previously | 16 |
cells were maintained in | 16 |
seven open reading frames | 16 |
infection of vero cells | 16 |
the porcine aminopeptidase n | 16 |
ion channel protein and | 16 |
coronaviruses in the genus | 16 |
as the reciprocal of | 16 |
infectivity of icpc a | 16 |
letter to the editor | 16 |
as a source of | 16 |
characterization of a variant | 16 |
the s proteins of | 16 |
as described in the | 16 |
of porcine circovirus type | 16 |
was supported by the | 16 |
of three independent experiments | 16 |
had no effect on | 16 |
of antibodies against porcine | 16 |
pedv classical attenuated vaccine | 16 |
of diarrhoea caused by | 16 |
clinical signs of ped | 16 |
protein is a class | 16 |
by the addition of | 16 |
serial propagation of porcine | 16 |
viral rna was extracted | 16 |
antibodies were detected in | 16 |
pedv strain pc a | 16 |
the activation of the | 16 |
pedv at an moi | 16 |
was first identified in | 16 |
diarrhea virus in cell | 16 |
were obtained from the | 16 |
of pedv s protein | 16 |
functional characterization of the | 16 |
end of the trial | 16 |
of the n protein | 16 |
for h at rt | 16 |
have been identified in | 16 |
characterization of the fusion | 16 |
the absence of trypsin | 16 |
is a highly contagious | 16 |
of the fusion core | 16 |
in this study was | 16 |
small and large intestines | 16 |
when compared to the | 16 |
of type i ifns | 15 |
has been reported that | 15 |
genomic rna and sg | 15 |
more than of the | 15 |
type i and iii | 15 |
all authors read and | 15 |
an equal volume of | 15 |
of transportation in spread | 15 |
transportation in spread of | 15 |
diarrhea virus infection of | 15 |
closely related to the | 15 |
in spread of porcine | 15 |
characterization of a novel | 15 |
the transmissible gastroenteritis virus | 15 |
epidemic diarrhea virus the | 15 |
the results of this | 15 |
in china isolation and | 15 |
has been reported in | 15 |
channel protein and regulates | 15 |
min at rt and | 15 |
avian coronaviruses in the | 15 |
diarrhea viruses from germany | 15 |
the results indicated that | 15 |
role of transportation in | 15 |
density to porcine epidemic | 15 |
of the viral genome | 15 |
pedv orf encodes an | 15 |
were washed twice with | 15 |
the genus deltacoronavirus supports | 15 |
epidemic of diarrhoea caused | 15 |
and then incubated with | 15 |
most closely related to | 15 |
that pedv n protein | 15 |
diarrhoea caused by porcine | 15 |
there was no significant | 15 |
was performed using the | 15 |
with pedv at a | 15 |
have been shown to | 15 |
and regulates virus production | 15 |
receptor density to porcine | 15 |
in the regulation of | 15 |
the reciprocal of the | 15 |
of the partial spike | 15 |
to the genus alphacoronavirus | 15 |
of sows with a | 15 |
assay for the detection | 15 |
were collected at hpi | 15 |
to the pig industry | 15 |
protein and regulates virus | 15 |
duration of the study | 15 |
infected or infected with | 15 |
vero cell attenuated porcine | 15 |
with pedv at an | 15 |
are summarized in table | 15 |
vero cells were treated | 15 |
the culture medium was | 15 |
previous studies have shown | 15 |
may be due to | 15 |
it has been demonstrated | 15 |
for h prior to | 15 |
membrane protein genes of | 15 |
in the us and | 15 |
genus deltacoronavirus supports bat | 15 |
diarrhea virus and transmissible | 15 |
in the lamina propria | 15 |
has been reported to | 15 |
in the spike protein | 15 |
contribution of the porcine | 15 |
paraformaldehyde for min at | 15 |
of the porcine aminopeptidase | 15 |
diarrhea virus field strains | 15 |
and porcine group a | 15 |
orf encodes an ion | 15 |
the inhibitory effects of | 15 |
investigation of porcine epidemic | 15 |
was propagated in vero | 15 |
h and then infected | 15 |
have been reported in | 15 |
in the orf a | 15 |
fecal viral rna shedding | 15 |
epidemic diarrhea virus variant | 15 |
was obtained from the | 14 |
nuclei were stained with | 14 |
contaminated feed as a | 14 |
diarrhea virus associated with | 14 |
partial spike glycoprotein gene | 14 |
incubated at room temperature | 14 |
investigation into the role | 14 |
the basis of the | 14 |
epidemic diarrhea virus associated | 14 |
followed by cycles of | 14 |
the swine industry in | 14 |
in a variety of | 14 |
infected cells per well | 14 |
at weeks of age | 14 |
under a fluorescence microscope | 14 |
the s protein was | 14 |
recombinant s domain of | 14 |
efficacy of vero cell | 14 |
pedv n protein was | 14 |
were inoculated orally with | 14 |
the partial spike glycoprotein | 14 |
diarrhea virus in southern | 14 |
the nucleotide sequence of | 14 |
diarrhea virus dr strain | 14 |
of the virus to | 14 |
there was no difference | 14 |
the role of potentially | 14 |
would like to thank | 14 |
has been demonstrated that | 14 |
did not show any | 14 |
states porcine epidemic diarrhea | 14 |
genotype b porcine epidemic | 14 |
diarrhea in swine porcine | 14 |
diarrhea and or vomiting | 14 |
declare no conflict of | 14 |
the institutional animal care | 14 |
of porcine enteric coronaviruses | 14 |
is a receptor for | 14 |
particles associated with porcine | 14 |
in the small and | 14 |
s and s t | 14 |
was removed and the | 14 |
have been reported to | 14 |
the late stage of | 14 |
of the s domain | 14 |
on porcine epidemic diarrhoea | 14 |
potentially contaminated feed as | 14 |
of vero cell attenuated | 14 |
immunogenicity and protective efficacy | 14 |
porcine epidemic diarrhoea in | 14 |
into the role of | 14 |
pedv n protein and | 14 |
interaction between irf and | 14 |
virus in southern germany | 14 |
a source of the | 14 |
and porcine epidemic diarrhoea | 14 |
recombinant porcine epidemic diarrhea | 14 |
are shown in table | 14 |
studies are needed to | 14 |
diarrhea virus and its | 14 |
glycoprotein gene of porcine | 14 |
were tested for the | 14 |
the sialic acid binding | 14 |
b porcine epidemic diarrhea | 14 |
was no significant difference | 14 |
coronavirus mouse hepatitis virus | 14 |
aminopeptidase n is not | 14 |
sensitivity and specificity of | 14 |
field isolates in korea | 14 |
diarrhea virus porcine epidemic | 14 |
in the gastrointestinal tract | 14 |
rapid detection of porcine | 14 |
at hpi and hpi | 14 |
with the n protein | 14 |
oral efficacy of vero | 14 |
region of the s | 14 |
china isolation and characterization | 14 |
daily for clinical signs | 14 |
a large number of | 14 |
cells were subjected to | 14 |
the virulence of pedv | 14 |
large deletions in the | 14 |
vero cells infected with | 14 |
can be used to | 14 |
cells were fixed and | 14 |
was extracted from the | 14 |
the deduced amino acid | 14 |
feed as a source | 14 |
for rapid detection of | 14 |
virus in serum and | 14 |
has been shown that | 14 |
cells were stained with | 14 |
terminal region of the | 14 |
was used to detect | 14 |
rna and sg mrna | 14 |
virus associated with growth | 14 |
and infected with pedv | 14 |
of viral rna in | 14 |
of the reemerging korean | 14 |
role of potentially contaminated | 14 |
to prevent and control | 14 |
the cell lysates were | 14 |
were found in the | 14 |
positive and negative controls | 14 |
of potentially contaminated feed | 14 |
room temperature for min | 13 |
cells were collected at | 13 |
i interferon production by | 13 |
in europe and asia | 13 |
deletion in the s | 13 |
are shown in fig | 13 |
s and n genes | 13 |
positive ec cells in | 13 |
of clinical signs and | 13 |
authors would like to | 13 |
pedv s protein was | 13 |
in intestinal epithelial cells | 13 |
between irf and tbk | 13 |
of the pedv strain | 13 |
cells in the presence | 13 |
of the pedv spike | 13 |
was approved by the | 13 |
authors declare no conflict | 13 |
strains with an intact | 13 |
it is important to | 13 |
the molecular biology of | 13 |
a critical role in | 13 |
efficacy of recombinant s | 13 |
of the s and | 13 |
was significantly lower than | 13 |
t cells were co | 13 |
in mesenteric lymph nodes | 13 |
on ice for min | 13 |
these results suggested that | 13 |
cellular receptor for pedv | 13 |
sequence and phylogenetic analysis | 13 |
caused huge economic losses | 13 |
in the us in | 13 |
virus prototype and s | 13 |
is worth noting that | 13 |
i and type iii | 13 |
cells were blocked with | 13 |
a key role in | 13 |
belongs to the genus | 13 |
in the healthy groups | 13 |
green monkey kidney cells | 13 |
in the positive control | 13 |
epidemic diarrhea virus into | 13 |
between the united states | 13 |
the invasion rates of | 13 |
the pedv s gene | 13 |
detection of pedv in | 13 |
the authors would like | 13 |
of the severe acute | 13 |
identification and characterization of | 13 |
was determined to be | 13 |
was performed using a | 13 |
in the control group | 13 |
the vero cells were | 13 |
amino acid sequence identity | 13 |
blood samples were collected | 13 |
vero cells were cultured | 13 |
amino acid sequence of | 13 |
epidemic diarrhea virus is | 13 |
was similar to that | 13 |
a role in the | 13 |
and protective efficacy of | 13 |
cells as described previously | 13 |
between porcine epidemic diarrhea | 13 |
cell entry of porcine | 13 |
isolate of porcine epidemic | 13 |
to the lack of | 13 |
cells were washed twice | 13 |
the first report of | 13 |
using graphpad prism software | 13 |
the infectivity of icpc | 13 |
in the p group | 13 |
in the feces of | 13 |
the expression level of | 13 |
with hematoxylin and eosin | 13 |
pp a and pp | 13 |
of a novel porcine | 13 |
high mortality in neonatal | 13 |
variants with high pathogenicity | 13 |
pedv s protein is | 13 |
transcription polymerase chain reaction | 13 |
the interaction between irf | 13 |
protein of the porcine | 13 |
significant economic losses in | 13 |
the spread of the | 13 |
times with pbs and | 13 |
genome sequences of the | 13 |
agent of porcine epidemic | 13 |
and porcine reproductive and | 13 |
compared to that of | 13 |
were performed using the | 13 |
susceptible to pedv infection | 13 |
it is known that | 13 |
spread of the virus | 13 |
deletions in the s | 13 |
epidemic diarrhea virus isolates | 13 |
the inhibitory effect of | 13 |
on the s protein | 13 |
clarified by centrifugation at | 13 |
pigs inoculated orally with | 13 |
and genetic characterization of | 13 |
phylogenetic trees were constructed | 13 |
pedv is an enveloped | 13 |
as well as in | 13 |
of apn positive cells | 13 |
it is worth noting | 13 |
serum samples were collected | 13 |
for an additional h | 13 |
virus variants with high | 13 |
detected outbreaks of porcine | 13 |
in the case of | 13 |
of recombinant s domain | 13 |
s protein of the | 13 |
were added to the | 13 |
in hek t cells | 13 |
other pedv reference strains | 13 |
from each group were | 13 |
via natural feeding behavior | 13 |
coe and rlppg f | 13 |
but not in the | 13 |
losses in the swine | 13 |
suppression of type i | 13 |
is a type i | 13 |
in the mesenteric lymph | 13 |
pedv infection in vero | 13 |
the crude extract containing | 13 |
source of the first | 13 |
the introduction of pedv | 13 |
alphacoronavirus in the family | 12 |
deletion porcine epidemic diarrhea | 12 |
diarrhea virus variants with | 12 |
elisa for the detection | 12 |
the limit of detection | 12 |
reverse transcription polymerase chain | 12 |
this article can be | 12 |
of the pedv n | 12 |
cells were maintained at | 12 |
evaluation of contaminated complete | 12 |
were observed between the | 12 |
virus and discovery of | 12 |
pigs following consumption via | 12 |
epidemic diarrhea in china | 12 |
analysis of membrane protein | 12 |
a herd of breeding | 12 |
a coronavirus related to | 12 |
diarrhea virus nucleocapsid protein | 12 |
for min at c | 12 |
for pedv and tgev | 12 |
to each well and | 12 |
piglets born to immunized | 12 |
herd of breeding and | 12 |
a cause of persistent | 12 |
terminal domain of the | 12 |
related to human coronavirus | 12 |
in vero cells as | 12 |
rectal swabs were collected | 12 |
are available from the | 12 |
rna was extracted using | 12 |
in the development of | 12 |
as well as to | 12 |
phylogenetic analysis of membrane | 12 |
complete feed as a | 12 |
diarrhea virus and discovery | 12 |
pedv s and s | 12 |
the mrna levels of | 12 |
virus as a cause | 12 |
following consumption via natural | 12 |
rna genome of approximately | 12 |
of membrane protein genes | 12 |
virus isolates in china | 12 |
and colostrum by indirect | 12 |
by western blot analysis | 12 |
the sequence of the | 12 |
virus and porcine respiratory | 12 |
of the pedv strains | 12 |
infected with pedv strains | 12 |
the culture supernatants were | 12 |
the orf a b | 12 |
washed twice with pbs | 12 |
for h followed by | 12 |
were randomly divided into | 12 |
of a recombinant swine | 12 |
were expressed as the | 12 |
in the orf gene | 12 |
type porcine epidemic diarrhea | 12 |
virulent strains of pedv | 12 |
coronavirus porcine epidemic diarrhea | 12 |
feed as a vehicle | 12 |
replaced with fresh dmem | 12 |
diarrhea virus infection in | 12 |
than that in the | 12 |
consumption via natural feeding | 12 |
numbers of pedv antigen | 12 |
a novel swine enteric | 12 |
plays a critical role | 12 |
of contaminated complete feed | 12 |
significantly higher than those | 12 |
a vehicle for porcine | 12 |
orf gene of wild | 12 |
s and s domains | 12 |
pbs for min at | 12 |
vehicle for porcine epidemic | 12 |
m and n genes | 12 |
evolutionary genetics analysis version | 12 |
passages in vero cells | 12 |
in any of the | 12 |
colostrum by indirect elisa | 12 |
article can be found | 12 |
and pathogenicity of global | 12 |
these data suggest that | 12 |
and the role of | 12 |
as well as a | 12 |
cells with bound tgev | 12 |
the reemerging korean pedv | 12 |
antigenicity and pathogenicity of | 12 |
cd t cell frequency | 12 |
contaminated complete feed as | 12 |
and discovery of a | 12 |
in the united kingdom | 12 |
end of the study | 12 |
diarrhea virus isolates in | 12 |
virus and porcine deltacoronavirus | 12 |
high sensitivity and specificity | 12 |
in the infected piglets | 12 |
in pbs for min | 12 |
the course of the | 12 |
g a pedv strain | 12 |
were obtained from a | 12 |
vero cells in the | 12 |
in agreement with the | 12 |
with pedv strains at | 12 |
were inoculated with the | 12 |
epidemic diarrhea virus variants | 12 |
was shown to be | 12 |
were approved by the | 12 |
results indicate that the | 12 |
in the s and | 12 |
the present study was | 12 |
in vero cells in | 12 |
been reported to be | 12 |
for h at c | 12 |
the united kingdom in | 12 |
crude extract containing coe | 12 |
losses to the pig | 12 |
in the context of | 12 |
have shown that the | 12 |
a recombinant swine enteric | 12 |
recombinant swine enteric coronavirus | 12 |
variant with a large | 12 |
in porcine epidemic diarrhea | 12 |
classical swine fever virus | 12 |
at h after transfection | 12 |
diarrhea virus in serum | 12 |
the viral spike protein | 12 |
amino acid sequences were | 12 |
serum and colostrum by | 12 |
the type i interferon | 12 |
for min and then | 12 |
in a herd of | 12 |
discovery of a recombinant | 12 |
pathogenicity of global porcine | 12 |
sequence of a novel | 12 |
acid sequences of the | 12 |
the nucleocapsid protein gene | 12 |
of the gds and | 12 |
american type culture collection | 12 |
which belongs to the | 12 |
were then incubated with | 12 |
natural science foundation of | 12 |
was used to determine | 12 |
late stage of infection | 12 |
was calculated using the | 12 |
protective efficacy of recombinant | 12 |
the care and use | 12 |
with the intracellular extracts | 12 |
for detection of pedv | 12 |
tested for the presence | 12 |
insertion deletion porcine epidemic | 12 |
an evaluation of contaminated | 12 |
identification of two novel | 12 |
a high mortality rate | 12 |
virulent porcine epidemic diarrhea | 12 |
the number of pedv | 12 |
two novel b cell | 11 |
cause of persistent diarrhoea | 11 |
for up to days | 11 |
supported by a grant | 11 |
epidemic diarrhea virus a | 11 |
nucleotide sequence of the | 11 |
of experimental cv coronavirus | 11 |
an acute and highly | 11 |
proteolytic activation of the | 11 |
epitopes on porcine epidemic | 11 |
on the s gene | 11 |
of a novel recombinant | 11 |
divided into three groups | 11 |
antigenic relationships among porcine | 11 |
of the virus and | 11 |
of pedv and tgev | 11 |
transmissible gastroenteritis virus strains | 11 |
usage and cell entry | 11 |
the integrity of the | 11 |
is associated with the | 11 |
of breeding and finishing | 11 |
were located in the | 11 |
all samples were tested | 11 |
centrifuged for min at | 11 |
genome of approximately kb | 11 |
as a receptor for | 11 |
a and g b | 11 |
porcine enteric coronaviruses and | 11 |
for the care and | 11 |
committee on taxonomy of | 11 |
the inoculum was removed | 11 |
is involved in the | 11 |
cell epitopes on porcine | 11 |
breeding and finishing pigs | 11 |
biological and physicochemical properties | 11 |
the s and n | 11 |
b cell epitopes on | 11 |
of persistent diarrhoea in | 11 |
the mucosal immune system | 11 |
nucleocapsid genes of porcine | 11 |
and porcine transmissible gastroenteritis | 11 |
bmc vet res doi | 11 |
statistical analyses were performed | 11 |
coronaviridae of the order | 11 |
were carried out in | 11 |
human immunodeficiency virus type | 11 |
virus nucleocapsid protein antagonizes | 11 |
weeks prior to farrowing | 11 |
human coronavirus e and | 11 |
clinical signs of diarrhea | 11 |
a gnotobiotic pig model | 11 |
viral rna in serum | 11 |
height to crypt depth | 11 |
after washing three times | 11 |
cd t cell frequencies | 11 |
can be used for | 11 |
be used as a | 11 |
an immunohistochemical investigation of | 11 |
international committee on taxonomy | 11 |
vero cells treated with | 11 |
and analysis of a | 11 |
of the negative control | 11 |
strain isolated in france | 11 |
the age of the | 11 |
the invasion efficiency of | 11 |
novel b cell epitopes | 11 |
villous epithelial cells of | 11 |
mock infected or infected | 11 |
sequence of the pedv | 11 |
based on the orf | 11 |
analysis of the complete | 11 |
sequestering the interaction between | 11 |
the complete genome of | 11 |
attenuated strains of porcine | 11 |
the spread of pedv | 11 |
the m protein of | 11 |
western blot analysis of | 11 |
the number of new | 11 |
of the innate immune | 11 |
receptor usage and cell | 11 |
of the family coronaviridae | 11 |
passage in vero cells | 11 |
way analysis of variance | 11 |
sows with a mild | 11 |
at pid compared to | 11 |
relationships among porcine epidemic | 11 |
phylogenetic trees based on | 11 |
t cells were transfected | 11 |
epidemic diarrhea virus outbreaks | 11 |
weaned pigs at pid | 11 |
classical attenuated vaccine strain | 11 |
experimental cv coronavirus enteritis | 11 |
coronavirus enteritis in piglets | 11 |
epidemic diarrhea s gene | 11 |
i and iii ifns | 11 |
in the infected groups | 11 |
the cells were infected | 11 |
persistent diarrhoea in a | 11 |
ec cells in the | 11 |
production by sequestering the | 11 |
genome sequencing and analysis | 11 |
a novel outbreak in | 11 |
study was funded by | 11 |
of two novel b | 11 |
cv coronavirus enteritis in | 11 |
in contrast to the | 11 |
pigs had significantly higher | 11 |
protein antagonizes beta interferon | 11 |
harbin veterinary research institute | 11 |
at a dilution of | 11 |
of the ica kit | 11 |
porcine epidemic diarrhea s | 11 |
to a final concentration | 11 |
incubated for min at | 11 |
ch jx and cv | 11 |
causative agent of porcine | 11 |
the presence of antibodies | 11 |
pedv n protein is | 11 |
in mice group g | 11 |
cd cd t cells | 11 |
and physicochemical properties of | 11 |
on taxonomy of viruses | 11 |
slips through us borders | 11 |
nucleocapsid protein gene of | 11 |
derivation of attenuated porcine | 11 |
against the s protein | 11 |
indel strain isolated in | 11 |
the complete s gene | 11 |
might be due to | 11 |
pedv cv and lnct | 11 |
of pedv infection in | 11 |
in china complete genome | 11 |
in cells treated with | 11 |
diarrhea virus outbreaks in | 11 |
in the production of | 11 |
have been used to | 11 |
detection of pedv antigen | 11 |
virus outbreaks in taiwan | 11 |
analysis showed that the | 11 |
suckling pigs compared to | 11 |
further studies are needed | 11 |
of the present study | 11 |
cells in the g | 11 |
infection of sows with | 11 |
among porcine epidemic diarrhea | 11 |
s and s subunits | 11 |
is based on the | 11 |
version of this article | 11 |
novel outbreak in belgium | 11 |
deadly pig virus slips | 11 |
diarrhea s gene indel | 11 |
virus strain from henan | 11 |
s gene indel strain | 11 |
the vero and ipec | 11 |
villous atrophy in the | 11 |
phylogenetic tree based on | 11 |
were fixed with formaldehyde | 11 |
the family coronaviridae of | 11 |
pathology of experimental cv | 11 |
high mortality rates in | 11 |
pig virus slips through | 11 |
transmissible gastroenteritis virus infection | 11 |
family coronaviridae of the | 11 |
the percentage of apn | 11 |
pcr was performed using | 11 |
colonic mucosa and content | 11 |
in the sera of | 11 |
due to the lack | 11 |
strains prevailing recently in | 11 |
with large deletions in | 11 |
the detection limits of | 11 |
cloning and sequence analysis | 11 |
a high level of | 11 |
antibody responses in serum | 11 |
virus field strains prevailing | 11 |
length genome sequence of | 11 |
by sequestering the interaction | 11 |
and cell entry of | 11 |
cells were harvested and | 11 |
sequencing and analysis of | 11 |
mouse proximal apn promoter | 11 |
resulting in significant economic | 11 |
villous and crypt epithelium | 11 |
compared to weaned pigs | 11 |
aminopeptidase n and its | 11 |
virus in south china | 11 |
the vero e cells | 11 |
stained with hematoxylin and | 11 |
of spike gene of | 11 |
against the pedv s | 11 |
was funded by the | 11 |
is the most abundant | 11 |
we were able to | 11 |
immunohistochemical investigation of porcine | 11 |
virus slips through us | 11 |
indel strain of porcine | 11 |
diarrhoea in a herd | 11 |
interferon production by sequestering | 11 |
may be involved in | 11 |
previous infection of sows | 11 |
with the results of | 11 |
prevention and control of | 11 |
pigs infected with porcine | 11 |
were blocked with bovine | 11 |
supernatants were collected at | 11 |
gene indel strain isolated | 11 |
mice orally immunized with | 11 |
against pedv in vero | 11 |
rapid differential detection of | 11 |
compared to those of | 11 |
prevailing recently in china | 11 |
medium was replaced with | 11 |
confirmed the presence of | 11 |
inoculated orally with pedv | 11 |
in a humidified co | 11 |
the content of the | 11 |
were inoculated with pedv | 11 |
field strains prevailing recently | 11 |
coronavirus infectious bronchitis virus | 11 |
of nucleocapsid genes of | 11 |
van cott et al | 11 |
were randomly assigned to | 11 |
diarrhea in piglets in | 10 |
diarrhoea virus as a | 10 |
severity of clinical signs | 10 |
and protection in conventional | 10 |
reciprocal of the highest | 10 |
for porcine epidemic diarrhoea | 10 |
antagonizes beta interferon production | 10 |
our data indicate that | 10 |
of the authors of | 10 |
of type i and | 10 |
elisa using monoclonal antibodies | 10 |
in the s region | 10 |
green monkey kidney cell | 10 |
novel swine enteric alphacoronavirus | 10 |
and ileum are the | 10 |
financial or personal relationship | 10 |
was defined as the | 10 |
analysis of a novel | 10 |
bias the content of | 10 |
samples were tested in | 10 |
plasma is not infectious | 10 |
mediated by the viral | 10 |
infected suckling pigs had | 10 |
the small intestines of | 10 |
virulent or attenuated porcine | 10 |
or infected with pedv | 10 |
dna and rna viruses | 10 |
europe and matters of | 10 |
of a coronavirus spike | 10 |
insertions and deletions in | 10 |
epidemiology and vaccine of | 10 |
of vero cells with | 10 |
is essential for induction | 10 |
the surface of the | 10 |
vaccine of porcine epidemic | 10 |
in vero cells and | 10 |
deposited in genbank under | 10 |
neutralizing antibodies in the | 10 |
pedv at a multiplicity | 10 |
in the phylogenetic tree | 10 |
higher than that in | 10 |
physicochemical properties of cell | 10 |
the cellular receptor for | 10 |
in the genbank database | 10 |
the creative commons attribution | 10 |
the role of apn | 10 |
personal relationship with other | 10 |
to be positive for | 10 |
national natural science foundation | 10 |
thirds of the genome | 10 |
in the healthy piglets | 10 |
pcr for the detection | 10 |
washed with pbs and | 10 |
beta interferon production by | 10 |
has been used to | 10 |
presence of pedv rna | 10 |
is not infectious to | 10 |
orally with ml of | 10 |
in a previous study | 10 |
essential for induction of | 10 |
was replaced with fresh | 10 |
of cells in the | 10 |
in the large intestine | 10 |
the s protein in | 10 |
is a major receptor | 10 |
from europe and matters | 10 |
of icpc a and | 10 |
pedv and tgev infection | 10 |
or bias the content | 10 |
people or organizations that | 10 |
of antibodies against pedv | 10 |
and mesenteric lymph nodes | 10 |
porcine cell cultures and | 10 |
the majority of the | 10 |
porcine plasma is not | 10 |
were treated with the | 10 |
organizations that could inappropriately | 10 |
a mild strain of | 10 |
a high degree of | 10 |
in response to pedv | 10 |
into s and s | 10 |
s protein is a | 10 |
monoclonal antibodies for the | 10 |
molecular characterization of the | 10 |
was first detected in | 10 |
used to amplify the | 10 |
three times with pbst | 10 |
for clinical signs of | 10 |
could inappropriately influence or | 10 |
other people or organizations | 10 |
and in the vero | 10 |
is essential for the | 10 |
was cloned into the | 10 |
at the day of | 10 |
tissue culture infective dose | 10 |
the in vitro prophylactic | 10 |
or personal relationship with | 10 |
n is a major | 10 |
and immunogenicity of recombinant | 10 |
innate immune responses to | 10 |
suckling pigs at pid | 10 |
and vaccine of porcine | 10 |
nucleocapsid protein antagonizes beta | 10 |
and matters of debate | 10 |
piglets infected with pedv | 10 |
and in situ hybridization | 10 |
the university of minnesota | 10 |
vero cells as described | 10 |
the presence of a | 10 |
be responsible for the | 10 |
were performed in triplicate | 10 |
authors of this paper | 10 |
outbreaks in south korea | 10 |
of the pedv genome | 10 |
in the pig industry | 10 |
each well and incubated | 10 |
passages in cell culture | 10 |
rna virus belonging to | 10 |
chinese porcine epidemic diarrhea | 10 |
than those in the | 10 |
detection and molecular diversity | 10 |
particles associated with diarrhea | 10 |
a vital role in | 10 |
the presence of ribavirin | 10 |
and in the ipec | 10 |
diarrhea virus variant with | 10 |
analyses based on the | 10 |
cell cultures and experimental | 10 |
were significantly lower than | 10 |
washing three times with | 10 |
or organizations that could | 10 |
novel recombinant porcine epidemic | 10 |
molecular biology of coronaviruses | 10 |
by a grant from | 10 |
cycles of denaturation at | 10 |
virus and its antibodies | 10 |
and incubated for min | 10 |
spike protein of the | 10 |
and fecal samples were | 10 |
analyses were performed using | 10 |
the development of effective | 10 |
virus rna present in | 10 |
pedv spike protein gene | 10 |
the remainder of the | 10 |
antibodies for the detection | 10 |
the authors of this | 10 |
protection against infection with | 10 |
igg and iga antibodies | 10 |
were monitored daily for | 10 |
major receptor for the | 10 |
monkey kidney cell line | 10 |
analyzed by western blotting | 10 |
at the beginning of | 10 |
results showed that pedv | 10 |
responses and protection in | 10 |
a retrospect from europe | 10 |
vero cells were pretreated | 10 |
plays a role in | 10 |
fecal pedv rna shedding | 10 |
gene of the porcine | 10 |
the global swine industry | 10 |
diversity of spike gene | 10 |
of peptide h on | 10 |
pigs orally inoculated with | 10 |
related to transmissible gastroenteritis | 10 |
to those in the | 10 |
inappropriately influence or bias | 10 |
at the late stage | 10 |
using monoclonal antibodies for | 10 |
care and use of | 10 |
rna present in commercial | 10 |
south dakota state university | 10 |
were challenged orally with | 10 |
from a novel outbreak | 10 |
between fcov type and | 10 |
a financial or personal | 10 |
detection and differentiation of | 10 |
jejunum and ileum are | 10 |
properties of cell culture | 10 |
villous height to crypt | 10 |
was present in the | 10 |
in the intestine of | 10 |
detection and genetic characterization | 10 |
vero cells grown in | 10 |
depletion of cellular cholesterol | 10 |
samples were collected at | 10 |
the presence of m | 10 |
in each group were | 10 |
coronavirus transmissible gastroenteritis virus | 10 |
were purchased from sigma | 10 |
of apn negative cells | 10 |
serum samples collected from | 10 |
relationship with other people | 10 |
as a viral deubiquitinase | 10 |
the s protein and | 10 |
s gene of the | 10 |
and experimental infection of | 10 |
the international committee on | 10 |
venezuelan equine encephalitis virus | 10 |
a novel recombinant porcine | 10 |
the first line of | 10 |
cultures and experimental infection | 10 |
the entire genome of | 10 |
that could inappropriately influence | 10 |
with the exception of | 10 |
retrospect from europe and | 10 |
portion of the s | 10 |
a major receptor for | 10 |
of the pedv outbreak | 10 |
to a nitrocellulose membrane | 10 |
present in commercial spray | 10 |
positive for pedv by | 10 |
binding domain complexed with | 10 |
fusion of the viral | 10 |
in colostrum and milk | 10 |
in a gnotobiotic pig | 10 |
enteric disease in pigs | 10 |
sense rna genome of | 10 |
and molecular characterization of | 10 |
s proteins on the | 10 |
and crypt epithelium of | 10 |
objective of this study | 10 |
plates were washed three | 10 |
pigs of different ages | 10 |
against infection with a | 10 |
pathogenesis of porcine epidemic | 10 |
the early stages of | 10 |
entry into host cells | 10 |
have been identified as | 10 |
by the institutional animal | 10 |
of the sars coronavirus | 10 |
at a density of | 10 |
the role of the | 10 |
in the negative control | 10 |
at days of age | 10 |
to the family coronaviridae | 10 |
molecular diversity of spike | 10 |
is related to the | 10 |
virus in porcine cell | 10 |
in porcine alveolar macrophages | 10 |
the amino acid sequences | 10 |
huge economic losses to | 10 |
bile and bile acids | 10 |
in vitro prophylactic effects | 10 |
influence or bias the | 10 |
protein of pedv is | 10 |
is not required for | 10 |
to further investigate the | 10 |
and deletions in the | 10 |
of the ohio state | 10 |
specific siga positive colostrum | 10 |
balb c mice were | 10 |
or attenuated porcine epidemic | 10 |
jnk and erk phosphorylation | 10 |
with other people or | 10 |
pigs infected with pedv | 10 |
epidemic diarrhea virus identification | 10 |
to human coronavirus e | 10 |
n protein of pedv | 10 |
data are shown as | 10 |
was no difference in | 10 |
the infected weaned pigs | 10 |
epidemic diarrhoea virus as | 10 |
were cloned into the | 10 |
infection of pigs of | 10 |
with a mild strain | 10 |
rates of the gds | 10 |
the g g phase | 10 |
the cd cd t | 10 |
in porcine cell cultures | 10 |
dried porcine plasma is | 10 |
and molecular diversity of | 10 |
were inoculated with kpedv | 10 |
this study was funded | 10 |
in the infected group | 10 |
in piglets born to | 10 |
divided into four groups | 10 |
swine porcine epidemic diarrhoea | 10 |
diarrhea virus and porcine | 10 |
activation of the porcine | 9 |
crude extract containing trimeric | 9 |
transmissible gastroenteritis and porcine | 9 |
colorado from the united | 9 |
infection in vero e | 9 |
currently circulating in the | 9 |
and feline infectious peritonitis | 9 |
genetic characterization of porcine | 9 |
immunodominant region of s | 9 |
subjected to virus isolation | 9 |
open access article distributed | 9 |
rotavirus in a gnotobiotic | 9 |
response to pedv infection | 9 |
fusion protein by trypsin | 9 |
is not a cellular | 9 |
with the pedv s | 9 |
epidemic diarrhea virus rna | 9 |
the results demonstrated that | 9 |
intestinal and fecal samples | 9 |
cells were overlaid with | 9 |
was considered statistically significant | 9 |
of the coronaviridae family | 9 |
type i ifn response | 9 |
determination of the nucleocapsid | 9 |
pedv in the presence | 9 |
compared to the control | 9 |
coronavirus spike fusion protein | 9 |
analysis of the porcine | 9 |
the orf gene and | 9 |
in vero cells at | 9 |
were calculated using the | 9 |
genome sequence of pedv | 9 |
and its inhibition by | 9 |
the original us pedv | 9 |
the amount of pedv | 9 |
and molecular epidemiology of | 9 |
antigenic relationship between the | 9 |
antibodies in serum samples | 9 |
causative agent of ped | 9 |
causes endoplasmic reticulum stress | 9 |
of n protein with | 9 |
could be used to | 9 |
of the creative commons | 9 |
to the best of | 9 |
cells were incubated for | 9 |
are expressed as mean | 9 |
e and porcine transmissible | 9 |
of q r on | 9 |
and rapid detection of | 9 |
was supported by a | 9 |
was carried out using | 9 |
epidemic diarrhea coronavirus spike | 9 |
to the order nidovirales | 9 |
heterogeneous nuclear ribonucleoprotein a | 9 |
the pedv strain cv | 9 |
a large amount of | 9 |
at room temperature and | 9 |
of pedv n and | 9 |
an original us porcine | 9 |
a significant increase in | 9 |
our data indicated that | 9 |
indel and pedv s | 9 |
detection of viral rna | 9 |
than those induced by | 9 |
antiviral innate immune response | 9 |
end of the experiment | 9 |
were positive for pdcov | 9 |
the best of our | 9 |
protective immunity to human | 9 |
at h after the | 9 |
characterization of pig epidemic | 9 |
not a cellular receptor | 9 |
protein is the most | 9 |
was added and incubated | 9 |
evidence of infectivity of | 9 |
pedv infection in the | 9 |
in viral entry and | 9 |
strain usa colorado from | 9 |
the differentially expressed genes | 9 |
new insights into the | 9 |
original us porcine epidemic | 9 |
was to determine the | 9 |
swine porcine epidemic diarrhea | 9 |
viral rna at long | 9 |
the s gene and | 9 |
at rt and then | 9 |
p e d v | 9 |
analysis of the s | 9 |
attenuated vaccine strain cv | 9 |
the pathogenesis of pedv | 9 |
virus from a novel | 9 |
with an equal volume | 9 |
has a financial or | 9 |
were used to amplify | 9 |
in gilts and sows | 9 |
may play an important | 9 |
presence of pedv in | 9 |
pedv in the field | 9 |
well and incubated at | 9 |
respiratory syndrome virus nucleocapsid | 9 |
our understanding of the | 9 |
characterized by watery diarrhea | 9 |
fold serial dilutions of | 9 |
that the s protein | 9 |
detection of airborne viral | 9 |
the mouse proximal apn | 9 |
for rapid differential detection | 9 |
severe diarrhea and vomiting | 9 |
in the early stage | 9 |
infectivity of airborne porcine | 9 |
at g for min | 9 |
and viral modulation of | 9 |
immune evasion of porcine | 9 |
molecular characterization of porcine | 9 |
the highest serum dilution | 9 |
the antigenic relationship between | 9 |
of pedv have been | 9 |
at a final concentration | 9 |
proteins have been identified | 9 |
be divided into two | 9 |
results are expressed as | 9 |
number of new cases | 9 |
the detection of the | 9 |
in the intestines of | 9 |
pedv as well as | 9 |
incubated for an additional | 9 |
tcid ml of pedv | 9 |
were then washed with | 9 |
the severity of clinical | 9 |
by the viral spike | 9 |
a simple method of | 9 |
a and g a | 9 |
and downstream mediators on | 9 |
the national natural science | 9 |
note springer nature remains | 9 |
the levels of pedv | 9 |
terminus of the s | 9 |
protein gene of the | 9 |
high mortality in suckling | 9 |
orally immunized with rlppg | 9 |
strains at h after | 9 |
and cloned into the | 9 |
could provide piglets against | 9 |
vero cells grown on | 9 |
diarrhea virus strain usa | 9 |
phylogenetic analysis of nucleocapsid | 9 |
diarrhea virus confers protection | 9 |
paper has a financial | 9 |
prrsv and pedv were | 9 |
severe watery diarrhea and | 9 |
and evolution of the | 9 |
is an open access | 9 |
of a new porcine | 9 |
cleavage of the s | 9 |
pigs exposed to virulent | 9 |
reemerging porcine epidemic diarrhea | 9 |
based on the nucleotide | 9 |
attenuated vaccine strains and | 9 |
groups a and b | 9 |
with acute diarrhea in | 9 |
of pedv antigen in | 9 |
high mortality in piglets | 9 |
for induction of neutralizing | 9 |
virus and detection of | 9 |
provide piglets against homologous | 9 |
this s indirect elisa | 9 |
pcr and virus isolation | 9 |
diarrhea virus in swine | 9 |
an open access article | 9 |
of acute pedv infection | 9 |
entry mediated by the | 9 |
in the number of | 9 |
the detection of antibodies | 9 |
of the expression of | 9 |
attenuated porcine epidemic diarrhoea | 9 |
analysis of nucleocapsid genes | 9 |
spike fusion protein by | 9 |
and the presence of | 9 |
trypsin in cell culture | 9 |
antiviral activity of ribavirin | 9 |
modulation of antiviral innate | 9 |
of coronavirus cell entry | 9 |
of infectivity of airborne | 9 |
long distances from infected | 9 |
samples were subjected to | 9 |
our results suggest that | 9 |
virus infection of naive | 9 |
virus porcine epidemic diarrhoea | 9 |
diarrhea virus in portugal | 9 |
and gds strains were | 9 |
of pedv and other | 9 |
epidemic diarrhea virus replication | 9 |
based on the complete | 9 |
molecular characterization of pig | 9 |
replicates in porcine alveolar | 9 |
the random forest model | 9 |
were used in this | 9 |
were determined to be | 9 |
of pigs of different | 9 |
mild strain of porcine | 9 |
distributed under the terms | 9 |
results indicated that pedv | 9 |
in the replication of | 9 |
be involved in the | 9 |
development and evaluation of | 9 |
antibodies were purchased from | 9 |
the data indicated that | 9 |
rna at long distances | 9 |
the primary sites of | 9 |
of the interaction between | 9 |
with other pedv strains | 9 |
a and pp ab | 9 |
confers protection against infection | 9 |
the function of the | 9 |
airborne viral rna at | 9 |
was first discovered in | 9 |
diarrhea virus rna present | 9 |
for samples stored at | 9 |
shedding was detected in | 9 |
on the antigenic relationship | 9 |
cells were then washed | 9 |
mechanisms of coronavirus cell | 9 |
transmissible gastroenteritis virus in | 9 |
at the indicated times | 9 |
simple method of estimating | 9 |
transferred to a nitrocellulose | 9 |
were deposited in the | 9 |
was determined by a | 9 |
evasion of porcine enteric | 9 |
invasion efficiency of pedv | 9 |
immune responses induced by | 9 |
best of our knowledge | 9 |
the pedv genome is | 9 |
the cbp degradation by | 9 |
and detection of airborne | 9 |
extract containing trimeric coe | 9 |
were collected from piglets | 9 |
positive for pedv rna | 9 |
at h post infection | 9 |
membranes were incubated with | 9 |
of this paper has | 9 |
in the online version | 9 |
of a novel swine | 9 |
in vero and ipec | 9 |
hybridization for the detection | 9 |
diarrhea virus from a | 9 |
enteric coronaviruses and viral | 9 |
tge ped detection kit | 9 |
piglets against homologous challenge | 9 |
was visualized using a | 9 |
infected pigs at pids | 9 |
on the viral surface | 9 |
the production of type | 9 |
epidemic diarrhea virus shedding | 9 |
exposed to virulent or | 9 |
to determine whether pedv | 9 |
observed in this study | 9 |
the genetic diversity of | 9 |
the porcine apn transgene | 9 |
crude extract against pedv | 9 |
herpes simplex virus type | 9 |
n protein prolongs s | 9 |
trees based on the | 9 |
by the ministry of | 9 |
exhibited lower antigenic indexes | 9 |
the infected cells were | 9 |
respiratory syndrome coronavirus spike | 9 |
the first case of | 9 |
may contribute to the | 9 |
infected with pedv non | 9 |
fcov type specific sera | 9 |
moi of for h | 9 |
were found to have | 9 |
epidemic diarrhea virus confers | 9 |
of middle east respiratory | 9 |
diarrhea coronavirus spike fusion | 9 |
differential detection of transmissible | 9 |
isolated from a suckling | 9 |
of the most important | 9 |
of an original us | 9 |
the attachment and entry | 9 |
alpha minimum essential medium | 9 |
cov pl pro s | 9 |
virus is essential for | 9 |
pedv rna in the | 9 |
distances from infected herds | 9 |
is the causative agent | 9 |
science foundation of china | 9 |
coronaviruses and viral modulation | 9 |
isolated in japan from | 9 |
for the purpose of | 9 |
virus confers protection against | 9 |
investigate the effect of | 9 |
virus strain usa colorado | 9 |
method of estimating fifty | 9 |
without blfp crude extract | 9 |
in situ hybridization for | 9 |
of the assay was | 9 |
infection of naive pigs | 9 |
ped was first reported | 9 |
induces endoplasmic reticulum stress | 9 |
infection with a severe | 9 |
cells were incubated at | 9 |
of the partial s | 9 |
g b and g | 9 |
in europe in the | 9 |
porcine hemagglutinating encephalomyelitis virus | 9 |
viruses isolated in japan | 9 |
access article distributed under | 9 |
recombinant s protein was | 9 |
of airborne viral rna | 9 |
relationship between the coronavirus | 9 |
in a humidified incubator | 9 |
with porcine reproductive and | 9 |
proteolytic cleavage of the | 9 |
and deduced amino acid | 9 |
orally inoculated with the | 9 |
usa colorado from the | 9 |
by trypsin in cell | 9 |
syndrome virus nucleocapsid protein | 9 |
production of type i | 9 |
cell entry mediated by | 9 |
percentage of sows mated | 9 |
culture supernatants were collected | 9 |
the cells were blocked | 9 |
mouse hepatitis virus strain | 9 |
pedv icpc a and | 9 |
this paper has a | 9 |
conventional pigs exposed to | 9 |
protein by trypsin in | 9 |
virulent strain of pedv | 9 |
j cells were transfected | 9 |
n is a receptor | 9 |
from a suckling piglet | 9 |
of airborne porcine epidemic | 9 |
inoculum was removed and | 9 |
the virulence of the | 9 |
our data showed that | 9 |
virus belonging to the | 9 |
based on the sequence | 9 |
signs of diarrhea and | 9 |
diarrhea virus and the | 9 |
positive ec cells were | 9 |
in conventional pigs exposed | 9 |
phylogenetic tree was constructed | 9 |
coronavirus e and porcine | 9 |
values are expressed as | 9 |
plates were infected with | 9 |
data are expressed as | 9 |
coronavirus cell entry mediated | 9 |
reemerging korean pedv strains | 9 |
as described previously with | 9 |
fecal and serum samples | 9 |
viral modulation of antiviral | 9 |
diarrhea virus into vero | 9 |
subtypes g and g | 9 |
diarrhea virus is essential | 9 |
of pedv icpc a | 9 |
assays for the detection | 9 |
in the serum of | 9 |
of the us strains | 9 |
blfp crude extract against | 9 |
study on the antigenic | 9 |
article distributed under the | 9 |
shown in figure b | 9 |
were consistent with the | 9 |
total number of pigs | 9 |
differential detection of porcine | 9 |
pigs experimentally infected with | 9 |
in the s domain | 9 |
were washed once with | 9 |
m and orf genes | 9 |
mice vaccinated with the | 9 |
discovery of a novel | 9 |
nucleocapsid and spike protein | 9 |
serial passages in vero | 9 |
losses to the global | 9 |
clinical signs of pedv | 9 |
of antiviral innate signaling | 9 |
epidemic diarrhea virus subtypes | 9 |
at long distances from | 9 |
the role of viral | 9 |
and rnase treated vaccine | 9 |
cellular receptor of porcine | 9 |
of mice vaccinated with | 9 |
significant differences between the | 9 |
vero cells with the | 9 |
the rapid spread of | 9 |
pedv at a moi | 8 |
of an enteric infection | 8 |
these results revealed that | 8 |
provided by state and | 8 |
followed by incubation with | 8 |
respiratory syndrome coronavirus infection | 8 |
not infectious to naive | 8 |
of pedv in vitro | 8 |
may be related to | 8 |
pig epidemic diarrhoea viruses | 8 |
viral entry and pathogenesis | 8 |
of the dna damage | 8 |
isolated from kefir grains | 8 |
pedv was first reported | 8 |
at the indicated time | 8 |
incubated with mouse anti | 8 |
after the onset of | 8 |
gastroenteritis virus infection in | 8 |
the yc pedv strain | 8 |
research was supported by | 8 |
cells of the small | 8 |
cell frequencies in blood | 8 |
cats and chinese ferret | 8 |
in gnotobiotic pigs porcine | 8 |
of the transmissible gastroenteritis | 8 |
were subjected to three | 8 |
comparison between the united | 8 |
an enteric infection in | 8 |
in pbs at rt | 8 |
pedv was detected in | 8 |
in this study we | 8 |
an elisa for the | 8 |
deletion in the orf | 8 |
test for the detection | 8 |
support were provided by | 8 |
was chosen as the | 8 |
sequence of the spike | 8 |
tree based on the | 8 |
immunofluorescent study on the | 8 |
reveals a polymorphic orf | 8 |
is characterized by vomiting | 8 |
a devastating enteric disease | 8 |
were incubated with pedv | 8 |
might be associated with | 8 |
in the supernatants of | 8 |
in the beijing area | 8 |
constructed from the aligned | 8 |
genetic characterization of deltacoronavirus | 8 |
pigs at pids and | 8 |
coronavirus related to human | 8 |
this virus is a | 8 |
from porcine epidemic diarrhea | 8 |
twice with pbs and | 8 |
of the intestinal epithelium | 8 |
pedv strains in this | 8 |
of an indirect elisa | 8 |
epidemic diarrhoea viruses isolated | 8 |
pcr assay for the | 8 |
of deltacoronavirus in pigs | 8 |
a humidified co incubator | 8 |
are the primary sites | 8 |
corresponding author on reasonable | 8 |
sequence determination of the | 8 |
flexible strategies for multiple | 8 |
host innate immune responses | 8 |
the highly virulent pedv | 8 |
pathogenesis comparison between the | 8 |
and severe acute respiratory | 8 |
pigs inoculated with the | 8 |
is important for the | 8 |
partial s gene sequences | 8 |
on vero cell monolayers | 8 |
from mesenteric lymph nodes | 8 |
treated with different concentrations | 8 |
university institutional animal care | 8 |
strains in this study | 8 |
of the korean pedv | 8 |
agricultural research and development | 8 |
that the recombinant s | 8 |
s indirect elisa was | 8 |
the n protein is | 8 |
studies have demonstrated that | 8 |
associated with cell adaptation | 8 |
strategies for multiple sequence | 8 |
vaccines emergence of porcine | 8 |
to be associated with | 8 |
nucleocapsid protein of porcine | 8 |
of coronavirus attachment to | 8 |
of a liquid antimicrobial | 8 |
impact on the swine | 8 |
used to detect pedv | 8 |
in piglets less than | 8 |
and chinese ferret badgers | 8 |
update on porcine epidemic | 8 |
in the usa in | 8 |
were subjected to sds | 8 |
seems to be a | 8 |
purchased from santa cruz | 8 |
virulent parental attenuated strains | 8 |
emerging and reemerging epizootic | 8 |
and spike protein genes | 8 |
to the cytoplasm and | 8 |
in swine farms in | 8 |
the terms and conditions | 8 |
were washed times with | 8 |
available from the corresponding | 8 |
acting as a viral | 8 |
for multiple sequence alignment | 8 |
of the vero cells | 8 |
virus n protein prolongs | 8 |
t cell frequency in | 8 |
diarrhea virus identification of | 8 |
nucleocapsid protein of sars | 8 |
research support were provided | 8 |
to those of other | 8 |
antibody responses and protection | 8 |
of coronavirus spike proteins | 8 |
was first described in | 8 |
promotes its infectivity via | 8 |
identified in the us | 8 |
content of the paper | 8 |
prevalence of porcine epidemic | 8 |
united states and canada | 8 |
approved by the institutional | 8 |
classical and variant virulent | 8 |
and the results are | 8 |
in the icpc a | 8 |
epidemiological status of pedv | 8 |
inoculated orally with ml | 8 |
production of neutralizing antibodies | 8 |
were cultured in alpha | 8 |
blocking elisa using monoclonal | 8 |
plates were incubated at | 8 |
protein genes reveals a | 8 |
intestinal epithelial cell line | 8 |
i interferon pathway by | 8 |
effusion disease in rabbits | 8 |
with large genomic deletion | 8 |
different from those of | 8 |
faculty of veterinary medicine | 8 |
data are presented as | 8 |
as well as other | 8 |
these results demonstrated that | 8 |
the course of infection | 8 |
impacts of porcine epidemic | 8 |
of porcine transmissible gastroenteritis | 8 |
papn ectodomain and pedv | 8 |
by acting as a | 8 |
the infection of pedv | 8 |
cells were permeabilized with | 8 |
were rinsed with pbs | 8 |
the nucleotide and amino | 8 |
in south korea in | 8 |
the mechanism by which | 8 |
pigs in each group | 8 |
severe diarrhea and or | 8 |
the membrane was incubated | 8 |
mean numbers of serotonin | 8 |
viral protein nsp in | 8 |
cells and and in | 8 |
the s gene is | 8 |
the coronavirus transmissible gastroenteritis | 8 |
were plotted using imagej | 8 |
to pedv infection and | 8 |
the murine coronavirus spike | 8 |
the pathogenesis of an | 8 |
during the course of | 8 |
your next manuscript to | 8 |
prevailing in central china | 8 |
analysis of porcine deltacoronavirus | 8 |
diarrhoea virus and transmissible | 8 |
and and in the | 8 |
were extracted using the | 8 |
infected weaned pigs had | 8 |
strains in conventional neonatal | 8 |
was measured at nm | 8 |
probably due to the | 8 |
and embedded in paraffin | 8 |
findings of this study | 8 |
circulating in the us | 8 |
in the jejunum of | 8 |
state and federal funds | 8 |
based on the results | 8 |
is a coronavirus related | 8 |
to host aminopeptidase n | 8 |
entry of the porcine | 8 |
comparative genomic analysis of | 8 |
of the murine coronavirus | 8 |
supported by the national | 8 |
spike genes of porcine | 8 |
of classical and variant | 8 |
on the expression of | 8 |
aided by quality analysis | 8 |
nk cell frequencies in | 8 |
protection in conventional pigs | 8 |
genes induced by ifn | 8 |
cv vero adapted strain | 8 |
characteristics of the spike | 8 |
protein causes endoplasmic reticulum | 8 |
to be free of | 8 |
the phylogenetic tree based | 8 |
and federal funds appropriated | 8 |
emergence of pedv in | 8 |
by quality analysis tools | 8 |
interferon pathway by acting | 8 |
epidemic diarrhea virus coronavirus | 8 |
pbs at rt for | 8 |
infects and replicates in | 8 |
parental attenuated strains of | 8 |
to the original us | 8 |
the rest of the | 8 |
this research was supported | 8 |
to better understand the | 8 |
microscope coverslips placed in | 8 |
types of pedv strains | 8 |
no conflicts of interest | 8 |
a total volume of | 8 |
virus and degradation of | 8 |
throughout the small intestine | 8 |
ohio department of agriculture | 8 |
virus confirms that this | 8 |
protein is responsible for | 8 |
epidemic diarrhea virus c | 8 |
the iowa state university | 8 |
was not detected in | 8 |
epizootic swine virus porcine | 8 |
high mortality rate in | 8 |
after three washes with | 8 |
other cov n proteins | 8 |
used to determine the | 8 |
than that of cv | 8 |
coronavirus attachment to host | 8 |
and clarified by centrifugation | 8 |
the infectivity of pedv | 8 |
porcine epidemic diarrhoea porcine | 8 |
infection with porcine epidemic | 8 |
cholesterol is required for | 8 |
enteric infection in pigs | 8 |
these findings suggest that | 8 |
into vero e cells | 8 |
grown on microscope coverslips | 8 |
reemerging epizootic swine virus | 8 |
study are available from | 8 |
pretreated vero cells with | 8 |
against the n protein | 8 |
showing a positive signal | 8 |
submit your next manuscript | 8 |
enteric disease characterized by | 8 |
virus shedding in the | 8 |
the prevalence of pedv | 8 |
and reemerging epizootic swine | 8 |
endoplasmic reticulum stress and | 8 |
it is likely that | 8 |
with other pedv reference | 8 |
of korean pedv field | 8 |
type i ifn signaling | 8 |
and pedv n protein | 8 |
in vero cells infected | 8 |
virus genome using targeted | 8 |
kit according to the | 8 |
variants with large deletions | 8 |
nsp in irf signaling | 8 |
an emerging and reemerging | 8 |
higher than those of | 8 |
piglets infected with porcine | 8 |
of two porcine epidemic | 8 |
of piglets born to | 8 |
its inhibition by neutralizing | 8 |
under the terms and | 8 |
with pedv in the | 8 |
that there is a | 8 |
the development of new | 8 |
genome between the nucleocapsid | 8 |
virus and the role | 8 |
it has been suggested | 8 |
and degradation of creb | 8 |
genome structure and replication | 8 |
are closely related to | 8 |
kindly provided by dr | 8 |
coronavirus spike proteins in | 8 |
in the middle of | 8 |
genomic analysis of classical | 8 |
of pedv in swine | 8 |
federal funds appropriated to | 8 |
have contributed to the | 8 |
alignment aided by quality | 8 |
showed that pedv infection | 8 |
article is an open | 8 |
analysis of classical and | 8 |
of the membrane protein | 8 |
for prrsv and pedv | 8 |
for h and infected | 8 |
centrifuged at rpm for | 8 |
and variant virulent parental | 8 |
scale outbreak of diarrhea | 8 |
diarrhea virus genome between | 8 |
staining was visualized using | 8 |
variant virulent parental attenuated | 8 |
pcr assays for the | 8 |
inhibition by neutralizing antibodies | 8 |
infectious to naive pigs | 8 |
to biomed central and | 8 |
the nuclear translocation of | 8 |
hepatitis virus strain a | 8 |
role of viral protein | 8 |
a crucial role in | 8 |
and specificity of the | 8 |
protein nsp in irf | 8 |
with bound tgev purdue | 8 |
proteins in viral entry | 8 |
states porcine epidemic diarrhoea | 8 |
interferon restriction by porcine | 8 |
in the endoplasmic reticulum | 8 |
diarrhea virus by duplex | 8 |
cellular entry of the | 8 |
survival of pedv in | 8 |
evaluation of porcine epidemic | 8 |
airborne porcine epidemic diarrhea | 8 |
epidemic diarrhea virus on | 8 |
virulent genotype b porcine | 8 |
using targeted rna recombination | 8 |
of the disease in | 8 |
experimentally induced by the | 8 |
a high number of | 8 |
with porcine respiratory coronavirus | 8 |
with pedv at moi | 8 |
orf a b gene | 8 |
porcine small intestine epithelial | 8 |
were added to each | 8 |
at the protein level | 8 |
clinical signs were observed | 8 |
the cells were harvested | 8 |
the porcine reproductive and | 8 |
stage of pedv infection | 8 |
and immunofluorescent study on | 8 |
between the nucleocapsid and | 8 |
those induced by ifn | 8 |
and conditions of the | 8 |
of tbk or irf | 8 |
the intestinal lamina propria | 8 |
of porcine deltacoronavirus in | 8 |
to determine the effect | 8 |
virus by duplex rt | 8 |
for min and washed | 8 |
cells were detected in | 8 |
coronavirus related to transmissible | 8 |
spike protein genes reveals | 8 |
vero cells were incubated | 8 |
in the previous study | 8 |
of pedv has been | 8 |
incubated at c for | 8 |
and hpi for qrt | 8 |
virus genome between the | 8 |
but promotes its infectivity | 8 |
epidemic diarrhoea virus infection | 8 |
based on the pedv | 8 |
enterocytes of the small | 8 |
epidemic diarrhea virus transmission | 8 |
encodes four structural proteins | 8 |
author on reasonable request | 8 |
induces antibodies that neutralize | 8 |
genes reveals a polymorphic | 8 |