quadgram

This is a table of type quadgram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

quadgram	frequency
severe acute respiratory syndrome	17101
acute respiratory syndrome coronavirus	8022
of severe acute respiratory	5074
middle east respiratory syndrome	3899
medrxiv a license to	3841
a license to display	3841
to display the preprint	3841
granted medrxiv a license	3841
license to display the	3841
display the preprint in	3840
who has granted medrxiv	3831
has granted medrxiv a	3831
is the author funder	3610
copyright holder for this	3524
the copyright holder for	3505
the preprint in perpetuity	3248
holder for this preprint	2725
east respiratory syndrome coronavirus	2580
acute respiratory distress syndrome	2545
certified by peer review	2396
not certified by peer	2394
was not certified by	2394
for this preprint this	2291
preprint this version posted	2291
this preprint this version	2291
in patients with covid	2282
which was not certified	2256
the severe acute respiratory	2020
for the treatment of	1998
with severe acute respiratory	1929
it is made available	1888
made available under a	1887
is made available under	1887
international license it is	1852
license it is made	1852
a l p r	1757
r n a l	1755
o u r n	1755
j o u r	1755
u r n a	1755
l p r e	1753
r o o f	1753
p r o o	1753
n a l p	1753
a is the author	1640
under a is the	1638
available under a is	1638
in patients with severe	1409
of patients infected with	1389
in the united states	1338
at the time of	1307
in the context of	1289
on the other hand	1286
the world health organization	1280
in the treatment of	1279
in the absence of	1278
disease control and prevention	1241
for disease control and	1190
as well as the	1111
reuse allowed without permission	1105
no reuse allowed without	1105
in the case of	1071
of a novel coronavirus	1044
of hospitalized patients with	1014
this article is protected	1013
is protected by copyright	1013
article is protected by	1013
patients with coronavirus disease	1010
systematic review and meta	967
clinical features of patients	960
patients with severe acute	953
in the presence of	952
of patients with covid	948
infected with novel coronavirus	929
the treatment of covid	924
a systematic review and	917
with novel coronavirus in	908
features of patients infected	904
patients infected with novel	900
of middle east respiratory	857
has been shown to	847
novel coronavirus in wuhan	837
it is important to	835
a novel coronavirus from	821
critically ill patients with	813
this this version posted	797
for this this version	797
holder for this this	797
for the detection of	783
patients with novel coronavirus	777
of the novel coronavirus	774
respiratory syndrome coronavirus infection	754
centers for disease control	739
patients with severe covid	734
acute respiratory syndrome in	732
patients infected with sars	715
hospitalized patients with covid	705
a retrospective cohort study	695
and clinical characteristics of	687
from patients with pneumonia	682
of coronavirus disease in	679
as a result of	635
with acute respiratory distress	635
is one of the	634
coronavirus disease in china	630
novel coronavirus from patients	629
of novel coronavirus pneumonia	629
coronavirus from patients with	628
patients with pneumonia in	627
in addition to the	625
on the basis of	625
characteristics of coronavirus disease	624
an important role in	623
the spread of the	622
was found to be	621
with pneumonia in china	621
by severe acute respiratory	618
of the severe acute	618
with a new coronavirus	615
clinical characteristics of coronavirus	614
of the spike protein	602
associated with a new	601
outbreak associated with a	599
a new coronavirus of	598
pneumonia outbreak associated with	598
new coronavirus of probable	597
of probable bat origin	597
a pneumonia outbreak associated	596
coronavirus of probable bat	596
at the same time	586
of the sars coronavirus	581
for the development of	574
for severe acute respiratory	573
r i p t	572
c r i p	572
s c r i	572
m a n u	570
n u s c	570
a n u s	570
u s c r	570
characteristics of cases of	564
hospitalized patients with novel	560
center for disease control	550
one of the most	547
clinical characteristics of cases	536
epidemiological and clinical characteristics	534
a large number of	534
depends on ace and	532
on ace and tmprss	531
and is blocked by	531
is blocked by a	530
blocked by a clinically	529
cell entry depends on	529
in patients with sars	528
entry depends on ace	528
ace and tmprss and	528
associated with severe acute	525
this version posted may	523
by a clinically proven	523
and tmprss and is	522
a clinically proven protease	522
tmprss and is blocked	521
in severe acute respiratory	519
at the end of	519
clinically proven protease inhibitor	519
were found to be	517
the authors declare that	515
clinical characteristics of hospitalized	514
after the onset of	511
and risk factors for	511
characteristics of hospitalized patients	509
of critically ill patients	508
this version posted september	503
preprint the copyright holder	502
novel coronavirus pneumonia in	501
in vitro and in	494
cases of novel coronavirus	493
have been shown to	491
the onset of symptoms	488
of the s protein	487
the middle east respiratory	478
this version posted august	477
novel coronavirus associated with	475
the total number of	475
a novel coronavirus associated	474
the spike protein of	473
of cases of novel	471
c e p t	470
and middle east respiratory	470
p t e d	469
c c e p	469
e p t e	469
no conflict of interest	468
with the novel coronavirus	468
coronavirus pneumonia in wuhan	467
a c c e	467
associated with acute respiratory	466
the end of the	465
outbreak of severe acute	464
coronavirus associated with severe	463
risk factors for mortality	460
a wide range of	460
e d m a	460
t e d m	460
d m a n	460
in the present study	459
the detection of sars	459
it is possible that	458
this version posted june	458
studies have shown that	455
play a role in	455
on the surface of	447
a functional receptor for	446
that they have no	445
infected pneumonia in wuhan	445
the course of the	441
tested positive for sars	441
the intensive care unit	436
in the pathogenesis of	431
been shown to be	429
can be used to	427
the authors declare no	427
factors for mortality of	421
to severe acute respiratory	420
clinical course and risk	419
for mortality of adult	418
course and risk factors	418
in hospitalized patients with	417
vitro and in vivo	416
in critically ill patients	416
adult inpatients with covid	415
the central nervous system	415
in a patient with	414
as shown in figure	413
mortality of adult inpatients	413
the presence of sars	412
of adult inpatients with	412
of patients with sars	412
spread of the virus	409
in the development of	406
respiratory syndrome coronavirus spike	406
respiratory syndrome coronavirus in	404
identification of a novel	404
spike protein of sars	401
by the world health	399
declare that they have	397
chinese center for disease	397
cd and cd t	396
in the setting of	395
epidemiology of novel coronavirus	394
is a functional receptor	391
the beginning of the	389
authors declare that they	385
detection of novel coronavirus	385
and epidemiology of novel	384
a report of cases	383
functional receptor for the	382
a novel coronavirus in	382
this version posted july	381
virus origins and receptor	380
for virus origins and	379
coronavirus in patients with	379
origins and receptor binding	379
implications for virus origins	378
in patients with coronavirus	374
food and drug administration	373
of the immune system	371
chronic obstructive pulmonary disease	370
syndrome in hong kong	368
respiratory syndrome in hong	368
was approved by the	367
structure of the sars	366
the severity of the	365
em structure of the	361
in vero e cells	357
efficacy and safety of	356
characterisation and epidemiology of	355
to be associated with	355
genomic characterisation and epidemiology	354
the treatment of sars	354
transmission dynamics in wuhan	353
in the general population	353
the chinese center for	352
during the course of	352
in the number of	351
diagnosis and treatment of	347
associated with the novel	346
for the management of	345
a systematic review of	345
an increased risk of	341
caused by severe acute	339
of the virus in	338
has been reported to	336
the s protein of	335
increase the risk of	335
on the use of	334
human respiratory disease in	334
early transmission dynamics in	334
of novel coronavirus in	332
it has been shown	331
infection prevention and control	331
antibody responses to sars	331
associated with human respiratory	330
new coronavirus associated with	329
a new coronavirus associated	329
with human respiratory disease	329
coronavirus associated with human	329
a familial cluster of	328
the presence of the	328
cause of severe acute	327
respiratory disease in china	326
as well as in	326
syndrome coronavirus spike protein	325
receptor for the sars	321
the novel coronavirus indicating	320
in the management of	319
ill patients with covid	318
and cd t cells	318
were more likely to	316
it has been reported	315
as shown in fig	315
play an important role	314
in the respiratory tract	314
in the prefusion conformation	312
novel coronavirus in patients	309
in accordance with the	307
important lessons from the	307
have been reported in	304
and important lessons from	304
a study of a	303
of and important lessons	303
it is likely that	303
reduce the risk of	302
characteristics of and important	302
the spread of sars	301
the rest of the	300
of pneumonia associated with	300
from the coronavirus disease	299
of a family cluster	299
the upper respiratory tract	297
in the form of	297
it should be noted	297
familial cluster of pneumonia	297
the results of the	296
lessons from the coronavirus	296
of personal protective equipment	295
pneumonia associated with the	295
spike in the prefusion	294
the receptor binding domain	294
during the sars outbreak	294
cluster of pneumonia associated	294
a risk factor for	293
functional receptor for sars	293
antigenicity of the sars	292
study of a family	292
studies are needed to	292
are more likely to	292
of angiotensin converting enzyme	291
ncov spike in the	291
from the chinese center	289
of patients with severe	289
the active site of	289
a role in the	289
similar to that of	288
this version posted october	288
and antigenicity of the	287
for the sars coronavirus	287
the crystal structure of	286
for the diagnosis of	285
treatment of severe acute	285
isolation and characterization of	285
it is necessary to	284
the role of the	283
the presence of a	283
the treatment of severe	282
at the beginning of	282
born to mothers with	281
cases from the chinese	281
enzyme is a functional	280
would like to thank	279
novel coronavirus indicating person	279
summary of a report	279
used in this study	279
of a report of	278
characteristics and outcomes of	278
study was approved by	278
the number of cases	278
s protein of sars	277
the centers for disease	277
we found that the	276
no conflicts of interest	276
to the development of	276
of the coronavirus disease	276
outcomes of critically ill	275
in the course of	274
the recently emerged novel	274
case of novel coronavirus	274
has been reported that	273
recently emerged novel coronavirus	273
and chloroquine effectively inhibit	273
chloroquine effectively inhibit the	273
of the virus and	273
effectively inhibit the recently	273
remdesivir and chloroquine effectively	273
inhibit the recently emerged	273
the early stage of	272
should be noted that	272
and the number of	271
may be due to	271
by the severe acute	271
an observational cohort study	271
and outcomes of critically	270
we would like to	269
the impact of the	268
plays an important role	267
with the use of	266
the early stages of	266
prevention and control of	266
by the novel coronavirus	265
a higher risk of	265
report of cases from	265
jurisdictional claims in published	264
has been reported in	264
the structure of the	264
regard to jurisdictional claims	264
remains neutral with regard	264
with regard to jurisdictional	264
neutral with regard to	264
in published maps and	264
to jurisdictional claims in	264
maps and institutional affiliations	264
claims in published maps	264
published maps and institutional	264
for the presence of	263
nature remains neutral with	263
a key role in	263
the incubation period of	263
a public health emergency	263
the diagnosis of covid	263
springer nature remains neutral	263
influenza a h n	262
in the lungs of	260
of cases from the	260
the development of a	259
novel coronavirus in the	258
converting enzyme is a	257
for the first time	257
has been shown that	256
the spread of covid	256
with respect to the	256
the lower respiratory tract	255
which was not peer	255
transcription polymerase chain reaction	255
as well as a	255
the context of the	255
respiratory distress syndrome and	254
has been associated with	253
is likely to be	253
the pathogenesis of sars	253
the functional receptor for	252
more likely to be	252
are shown in table	252
course of the disease	251
the severity of covid	251
days after symptom onset	251
the first case of	250
risk factors associated with	250
pathological findings of covid	250
outcomes of patients with	249
the early phase of	249
first case of novel	248
the expression of ace	248
have been associated with	247
in patients infected with	247
ill patients with sars	247
this work was supported	247
this is the first	246
note springer nature remains	246
important to note that	246
it was found that	246
as compared with sars	246
aerosol and surface stability	245
committee on taxonomy of	243
the majority of the	243
and surface stability of	243
can be found in	242
the fact that the	242
international committee on taxonomy	242
with novel coronavirus pneumonia	241
the surface of the	240
be used as a	240
is important to note	240
the risk of infection	240
clinical course and outcomes	239
the use of a	238
course and outcomes of	238
receptor for sars coronavirus	236
a review of the	235
the causative agent of	235
surface stability of sars	235
health emergency of international	234
of the immune response	234
the novel coronavirus from	233
transmission of the virus	233
were included in the	233
caused by a novel	232
days after the onset	232
and severe acute respiratory	232
of the virus to	232
this version posted april	232
have been reported to	232
outbreak of novel coronavirus	231
higher than that of	231
the time of the	230
virological assessment of hospitalized	230
a first step in	230
national health commission of	230
important role in the	230
work was supported by	230
there is no evidence	229
prevention and treatment of	229
tissue distribution of ace	228
public health emergency of	227
coronavirus in the united	226
with middle east respiratory	226
entry into host cells	226
the novel coronavirus disease	225
have the potential to	225
the context of covid	225
the efficacy and safety	225
to the ace receptor	224
first step in understanding	224
are summarized in table	223
declare no conflict of	223
mortality in patients with	223
emergency of international concern	223
treatment of patients with	223
as severe acute respiratory	223
and approved the final	223
a total of patients	223
structural basis for the	223
may play a role	222
is based on the	222
with the exception of	222
in response to the	222
the innate immune response	222
distribution of ace protein	221
in understanding sars pathogenesis	221
the international committee on	221
these results suggest that	221
step in understanding sars	221
to the lack of	220
this version posted november	220
multisystem inflammatory syndrome in	220
was supported by the	220
in upper respiratory specimens	220
for patients with covid	220
specimens of infected patients	218
of the viral genome	218
severity of the disease	217
the virus in the	217
in the spike protein	217
the innate immune system	217
inflammatory syndrome in children	216
authors declare no conflict	216
characterization of a novel	216
is consistent with the	216
assessment of hospitalized patients	215
viral load in upper	215
upper respiratory specimens of	214
load in upper respiratory	214
all over the world	213
in adults hospitalized with	213
on taxonomy of viruses	213
respiratory specimens of infected	213
review of the literature	213
with a history of	213
is associated with a	212
as shown in table	212
a better understanding of	212
cytokine storm syndromes and	211
consider cytokine storm syndromes	211
the outbreak of sars	211
of convalescent plasma therapy	211
a randomized clinical trial	210
a possible cause of	210
of viral rna in	210
human immunodeficiency virus type	209
has the potential to	209
the sars outbreak in	209
as part of the	209
transmission of severe acute	209
as a possible cause	209
storm syndromes and immunosuppression	209
spread of the disease	208
by a novel coronavirus	208
there was no significant	207
it is known that	207
death in patients with	207
in different types of	207
are likely to be	207
been reported to be	207
the diagnosis and treatment	206
species severe acute respiratory	206
hospitalized with severe covid	206
and the risk of	206
the immune response to	206
to the intensive care	206
may be related to	206
peripheral blood mononuclear cells	205
declare no competing interests	205
be due to the	205
adults hospitalized with severe	205
as a treatment of	204
of novel coronavirus disease	203
during the study period	203
the species severe acute	203
the case of sars	203
hydroxychloroquine and azithromycin as	202
preprint in the copyright	202
authors declare no competing	202
in the copyright holder	202
a member of the	202
be related to the	202
study clinical characteristics of	202
the preprint in the	202
it is difficult to	201
and azithromycin as a	201
ncov and naming it	201
the treatment of patients	201
of the disease and	201
a treatment of covid	201
was performed using the	201
the limit of detection	201
the time of writing	200
clinical characteristics of patients	200
possible cause of severe	200
and naming it sars	200
crystal structure of sars	199
innate and adaptive immune	199
coronavirus as a possible	199
azithromycin as a treatment	199
the basis of the	199
the use of the	199
of this study was	199
reverse transcription polymerase chain	198
between the two groups	198
there is an urgent	198
that the use of	198
can be used for	197
was added to the	197
sensitivity and specificity of	196
and clinical features of	196
can be used as	196
is responsible for the	196
management of patients with	195
to reduce the risk	195
in the intensive care	195
a critical role in	194
and treatment of covid	193
to the presence of	193
the spike glycoprotein of	193
a crucial role in	193
it is possible to	193
to better understand the	192
patients with severe disease	192
for the novel coronavirus	192
different types of clinical	191
results of an open	190
and viral load in	190
an analysis based on	190
in contrast to the	190
at room temperature for	190
structural studies of sars	190
into the host cell	189
types of clinical specimens	189
is an urgent need	189
of acute respiratory distress	189
for the prevention and	189
for the recognition of	189
as one of the	189
acute respiratory syndrome a	189
transcriptase polymerase chain reaction	188
and the use of	188
novel coronavirus from wuhan	188
has not yet been	188
we were able to	188
a trial of lopinavir	188
in the early stage	187
crystal structure of the	187
the onset of the	187
for the prevention of	186
in new york city	186
viral load in a	186
the creative commons attribution	186
severe cases of covid	186
and the presence of	186
it has been suggested	185
due to the lack	185
a small number of	184
inflammatory cytokines and chemokines	184
by the end of	184
the aim of this	184
to the fact that	184
is thought to be	184
the sensitivity of the	183
patients hospitalized with covid	183
to the use of	183
for detection of sars	183
the outbreak of covid	183
may be associated with	183
the vast majority of	183
ritonavir in adults hospitalized	183
immune response to sars	182
with suspected or confirmed	182
and shortness of breath	182
was used as a	182
novel coronavirus from a	181
analysis based on decade	181
spike glycoprotein of sars	181
was associated with a	181
long structural studies of	180
in vitro antiviral activity	180
manifestations of hospitalized patients	180
clinical characteristics of covid	180
safety and efficacy of	180
patients with acute respiratory	179
the transmission of sars	179
isolation of a novel	179
human airway epithelial cells	178
progression and viral load	178
from a man with	178
acute respiratory syndrome the	178
of the creative commons	178
for treatment of covid	178
in the current study	178
the absence of a	178
pneumonia in saudi arabia	178
with pneumonia in saudi	178
clinical progression and viral	178
in a community outbreak	178
response in patients with	178
an increase in the	177
distributed under the terms	177
a man with pneumonia	177
a descriptive study clinical	177
prevent the spread of	177
a result of the	177
man with pneumonia in	177
as the number of	177
national institutes of health	176
entry into the host	176
of the innate immune	176
a community outbreak of	176
china clinical characteristics of	176
igm and igg antibodies	176
coronavirus from a man	176
the activation of the	176
for critically ill patients	175
from a patient with	175
was shown to be	175
to that of the	175
the epidemiological characteristics of	175
and outcomes of patients	175
of the sars epidemic	175
novel severe acute respiratory	175
the risk of sars	174
in the early phase	174
origin and evolution of	174
basis for design of	174
a major outbreak of	174
a wide variety of	174
expression of ace in	174
load in a community	174
in the face of	173
to acute respiratory distress	173
to be able to	173
for the use of	173
the clinical characteristics of	173
porcine epidemic diarrhea virus	173
of viral load in	173
in the regulation of	173
as compared to the	173
has been found to	173
the s protein is	172
mechanism of action of	172
related to the sars	172
is mediated by the	172
the genome sequence of	172
orf a and orf	172
and personal protective equipment	171
basis for the recognition	171
for patients with severe	171
the protein data bank	171
that there is a	171
as well as to	171
our understanding of the	171
a patient with covid	171
early phase of the	170
and the development of	170
novel coronavirus infection in	170
the pathogenesis of covid	170
characteristics of novel coronavirus	170
the binding of the	170
by the fact that	169
have no conflict of	169
has been suggested that	169
in the majority of	169
is shown in figure	168
in a cohort of	168
was detected in the	168
was obtained from the	168
in the upper respiratory	168
infection from an asymptomatic	168
for middle east respiratory	167
the most common symptoms	167
these data suggest that	167
at the s s	167
article distributed under the	167
not included in the	167
be one of the	167
binding domain complexed with	167
of an outbreak of	166
of the number of	166
use of personal protective	166
for the diagnosis and	166
the first week of	166
after onset of symptoms	166
neonates born to mothers	165
to the sars coronavirus	165
pregnant women with covid	165
treatment of novel coronavirus	165
in view of the	165
the basic reproduction number	165
as a consequence of	165
this study was to	165
a randomized controlled trial	164
with coronavirus disease in	164
distress syndrome and death	164
the risk of transmission	164
by the presence of	164
it was reported that	163
upper and lower respiratory	163
of a patient with	163
it has also been	163
the expression of the	163
the sars coronavirus spike	163
the absence of any	163
major outbreak of severe	163
hospitalized patients with coronavirus	162
number of confirmed cases	162
in this study were	162
to the best of	162
detection of severe acute	162
in acute respiratory distress	162
the viral spike protein	162
the antiviral activity of	162
the size of the	162
in the early stages	162
respiratory syndrome coronavirus and	161
in the range of	161
disease prevention and control	161
the results showed that	161
a broad range of	161
the rapid spread of	161
the majority of patients	161
more likely to have	161
treatment of severe covid	161
potential conflict of interest	161
access article distributed under	161
the prevention and treatment	160
alone or in combination	160
of mouse hepatitis virus	160
the use of corticosteroids	160
caused by the novel	160
for each of the	159
have no competing interests	159
cases of severe acute	159
the sars epidemic in	159
as a function of	159
best of our knowledge	159
they have no competing	159
and death in patients	159
factors associated with acute	159
the best of our	158
used for the treatment	158
from an asymptomatic contact	158
the national health commission	158
informed consent was obtained	158
isolated from a patient	158
management of severe acute	158
in a mouse model	158
of the novel human	157
the number of patients	157
asymptomatic contact in germany	157
an asymptomatic contact in	157
prognosis in patients with	157
that there is no	157
of the sars outbreak	157
has also been reported	157
of patients with coronavirus	157
no significant difference in	157
little is known about	157
the diamond princess cruise	157
the stability of the	157
are shown in figure	156
in terms of the	156
the ability of the	156
s and s subunits	156
it was shown that	156
the epithelial cells of	156
syndrome and death in	155
outcomes in patients with	155
ncov infection from an	155
analyses were performed using	155
to prevent the spread	155
is known to be	155
the s and s	155
a potent inhibitor of	155
rna was detected in	155
were obtained from the	154
the nucleocapsid protein of	154
health commission of the	154
diamond princess cruise ship	154
of coronavirus spike proteins	154
the novel coronavirus sars	154
the replication of sars	154
been found to be	154
to the host cell	154
the d g mutation	154
at increased risk for	153
h n influenza virus	153
the acute phase of	153
protein of severe acute	153
of cd t cells	153
a high level of	152
a case series of	152
of the patients with	152
of sars and mers	152
binding domain of the	152
sequence of the sars	152
admitted to the hospital	152
and lower respiratory tract	152
viral load in the	152
to be involved in	152
it is worth noting	152
at increased risk of	152
and acute respiratory distress	152
the proximal origin of	152
of ace and tmprss	151
have shown that the	151
community outbreak of coronavirus	151
against severe acute respiratory	151
respiratory distress syndrome in	151
and evolution of pathogenic	151
caused by the severe	151
better understanding of the	151
evolution of pathogenic coronaviruses	151
the evolution of the	150
the case of the	150
a retrospective review of	150
the clinical course of	150
early stages of the	150
on the day of	150
or in combination with	150
proximal origin of sars	150
the impact of covid	149
in the event of	149
consent was obtained from	149
associated with an increased	149
in the middle east	148
associated with poor prognosis	148
has been detected in	148
parts of the world	148
the start of the	148
acute respiratory syndrome and	148
authors would like to	148
in the united kingdom	148
may contribute to the	147
in the control group	147
severe acute respiratory infection	147
of sars coronavirus spike	147
it is noteworthy that	147
the nature of the	147
pp a and pp	147
over the course of	147
the diagnosis of sars	147
as well as other	146
patients with middle east	146
posterior oropharyngeal saliva samples	146
confirmed cases of covid	146
to the severity of	146
in a variety of	146
of novel coronavirus infection	146
than that of the	146
angiotensin ii receptor blockers	146
during the incubation period	145
presence or absence of	145
rna dependent rna polymerase	145
accepted article this article	145
these findings suggest that	145
and characterization of a	145
the effect of the	145
article this article is	145
days after onset of	145
immune response in patients	145
in balb c mice	145
and serum antibody responses	145
carrier transmission of covid	144
asymptomatic carrier transmission of	144
in the field of	144
viral load in posterior	144
read and approved the	144
the ministry of health	144
convalescent plasma therapy in	143
in treatment of covid	143
load in posterior oropharyngeal	143
in posterior oropharyngeal saliva	143
similar to those of	143
was used for the	143
reverse transcriptase polymerase chain	143
for disease prevention and	143
the sensitivity and specificity	143
at high risk of	142
the potential risk of	142
in human airway epithelial	142
to be the most	142
from patients with covid	142
were positive for sars	142
a crucial role of	142
has been identified as	142
as soon as possible	142
have been found to	142
the presence of viral	142
analysis of the sars	142
were infected with sars	142
of viruses related to	141
were admitted to the	141
to that of sars	141
the emergence of sars	141
had a history of	141
coronavirus isolated from a	141
was observed in the	141
approved the final manuscript	141
antibody responses during infection	141
the interaction between the	141
to mothers with covid	141
receptor recognition by the	141
was not associated with	141
animals in southern china	141
at higher risk of	141
profiles of viral load	141
responses during infection by	140
serum antibody responses during	140
studies of sars coronavirus	140
of hepatitis c virus	140
is worth noting that	140
are included in the	140
could be used to	140
temporal profiles of viral	140
oropharyngeal saliva samples and	140
high expression of ace	140
samples and serum antibody	140
during infection by sars	140
of the international committee	140
it is clear that	140
from animals in southern	140
saliva samples and serum	140
recognition by the novel	140
recent insights into emerging	140
was defined as the	140
have also been reported	140
to the emergency department	140
one of the main	140
sars coronavirus from animals	139
were observed in the	139
role of angiotensin converting	139
insights into emerging coronaviruses	139
in patients with novel	139
a case report of	139
coronavirus from animals in	139
viruses related to the	139
of sars coronavirus infection	139
during the sars epidemic	139
an urgent need for	139
a major role in	139
cd t cell responses	139
of the patients were	139
and characterization of viruses	138
be explained by the	138
presumed asymptomatic carrier transmission	138
can be detected in	138
in relation to the	138
this study was approved	138
in the human population	138
the sars coronavirus from	138
the presence or absence	138
the performance of the	138
is supported by the	137
disease in china clinical	137
genome sequence of the	137
studies are required to	137
systematic review of the	137
of the ace receptor	137
further studies are needed	137
the median age of	137
was no significant difference	137
characterization of viruses related	137
in the active site	136
of human immunodeficiency virus	136
crucial role of angiotensin	136
were found to have	136
be involved in the	136
included in the study	136
included in this study	136
which is consistent with	136
endothelial cell infection and	136
analysis was performed using	136
t cell responses to	136
the purpose of this	135
the greater toronto area	135
cd t cells in	135
also been shown to	135
a and pp ab	135
epithelial cells of the	135
the duration of the	135
neurologic manifestations of hospitalized	135
the number of infected	135
early stage of the	134
the neuroinvasive potential of	134
in light of the	134
admitted to the icu	134
the host immune response	134
clinical management of severe	134
are listed in table	134
a novel coronavirus outbreak	134
was used as the	133
patients with confirmed covid	133
identification of severe acute	133
in patients with acute	133
of the n protein	133
patients admitted to the	133
with severe coronavirus disease	133
play a key role	133
for the study of	133
of the new coronavirus	133
the authors would like	133
novel coronavirus outbreak of	133
have been used to	133
in a recent study	133
written informed consent was	133
of influenza a virus	133
be considered as a	133
the media briefing on	132
before the onset of	132
of the spike glycoprotein	132
in combination with other	132
in a study of	132
remarks at the media	132
the disease caused by	132
a severe acute respiratory	132
at the media briefing	132
from severe acute respiratory	132
of lopinavir ritonavir in	132
is associated with the	132
the case of a	132
a final concentration of	132
has also been shown	132
is shown in fig	132
outbreak of global health	131
of the middle east	131
risk of transmission of	131
in the fight against	131
on the cell surface	131
review of medical records	131
suspected or confirmed covid	131
the mechanism of action	131
risk factors for severe	130
bound to the ace	130
in the near future	130
has been observed in	130
of the respiratory tract	130
an outbreak of novel	130
on the one hand	130
who tested positive for	130
in line with the	130
that can be used	130
domain of the spike	130
the peak of the	130
they have no conflict	130
mortality due to covid	130
at the university of	129
retrospective review of medical	129
cells were infected with	129
characteristics of an outbreak	129
it has been demonstrated	129
use of convalescent plasma	129
the analysis of the	129
in the peripheral blood	129
due to the high	129
in the process of	129
coronavirus outbreak of global	129
of global health concern	129
of ace in the	129
acute respiratory syndrome virus	128
available under a author	128
epidemiological characteristics of an	128
shown in figure a	128
infection and endotheliitis in	128
the united states and	128
are involved in the	128
and endotheliitis in covid	128
and angiotensin ii receptor	128
the results of this	128
the new york city	128
under a author funder	128
there is currently no	128
be taken into account	128
is considered to be	128
cell infection and endotheliitis	128
of sars coronavirus in	128
the recognition of sars	127
time polymerase chain reaction	127
increase in the number	127
in the new york	127
white blood cell count	127
the coronavirus study group	127
expression of ace and	127
as much as possible	127
in most of the	127
in the production of	127
domain bound to the	127
the prevention and control	126
in the s protein	126
in the greater toronto	126
mediated by the viral	126
the viral life cycle	126
an intensive care unit	126
european centre for disease	126
in close contact with	126
with an increased risk	126
there is a need	126
one of the major	126
the potential role of	125
hydroxychloroquine for the treatment	125
control the spread of	125
poor prognosis in patients	125
the novel coronavirus outbreak	125
are associated with poor	125
the risk of covid	125
neuroinvasive potential of sars	125
in the formation of	125
cases of coronavirus disease	125
will need to be	124
among health care workers	124
with poor prognosis in	124
severe acute respiratory distress	124
on the role of	124
the case fatality rate	124
that the majority of	124
patients infected with the	124
is known about the	124
were tested for sars	124
lower than that of	124
a and orf b	124
a prospective cohort study	124
global initiative on sharing	124
was first reported in	123
samples from patients with	123
since the beginning of	123
and its impact on	123
of the viral rna	123
of spike glycoprotein of	123
at a concentration of	123
a cluster of cases	123
that the number of	123
patients with sars in	123
of novel coronavirus diseases	123
caused by the sars	123
the study was approved	122
approved by the institutional	122
structure of sars coronavirus	122
the management of covid	122
it is essential to	122
vertical transmission potential of	122
and the cardiovascular system	122
min at room temperature	122
upper respiratory tract infection	122
of this study is	122
epub ahead of print	122
the lancet infectious diseases	122
clinical characteristics of novel	122
the extent to which	122
sars coronavirus nucleocapsid protein	122
centre for disease prevention	122
binding domain bound to	122
authors have declared that	122
incidence of thrombotic complications	122
the specificity of the	122
icu patients with covid	121
initiative on sharing all	121
induced acute lung injury	121
for up to days	121
on sharing all influenza	121
is caused by a	121
the s subunit of	121
has been used to	121
it is not clear	121
signs and symptoms of	121
stages of the disease	121
an update on the	121
cytokines and chemokines in	121
composition and divergence of	121
as well as for	121
is involved in the	120
in nine pregnant women	120
a high risk of	120
sharing all influenza data	120
lopinavir ritonavir in the	120
cases have been reported	120
tested negative for sars	120
of pregnant women with	120
in any of the	120
in patients with mild	120
intrauterine vertical transmission potential	120
genomic characterization of the	120
of thrombotic complications in	120
first case of covid	120
the ethics committee of	120
could be due to	120
the highest number of	120
china clinical features of	120
infants born to mothers	119
syndrome associated with sars	119
the origin of sars	119
the binding affinity of	119
an essential role in	119
the quality of the	119
vero e cells were	119
a significant role in	119
infection in nine pregnant	119
the characteristics of the	119
these results indicate that	119
the viral load in	119
the time of this	119
transmission potential of covid	119
of science and technology	119
clinical features of covid	119
to a lesser extent	119
ritonavir in the treatment	119
approved by the ethics	119
and intrauterine vertical transmission	118
statistical analyses were performed	118
short period of time	118
dosing design of hydroxychloroquine	118
a high degree of	118
is yet to be	118
in an attempt to	118
and the lack of	118
be responsible for the	118
characterization of the novel	118
did not show any	118
on the management of	118
specific cd t cells	118
mice transgenic for human	118
vitro antiviral activity and	118
during the coronavirus disease	118
samples were collected from	118
the first cases of	118
the outbreak of the	118
design of hydroxychloroquine for	118
domain complexed with receptor	118
of hydroxychloroquine for the	118
clinical characteristics and intrauterine	117
publicly reported confirmed cases	117
there is evidence that	117
by the addition of	117
in the control of	117
the virus and the	117
to the number of	117
and projection of optimized	117
the formation of the	117
is caused by the	117
pathology of severe acute	117
complications in critically ill	117
activity and projection of	117
is associated with decreased	117
projection of optimized dosing	117
and the pathogenesis of	117
was identified as the	117
antiviral activity and projection	117
respiratory syndrome coronavirus replication	117
characteristics and intrauterine vertical	117
effectiveness of convalescent plasma	117
due to lack of	117
on an analysis of	116
of immune response in	116
abnormal coagulation parameters are	116
to the world health	116
were included in this	116
in agreement with the	116
at the level of	116
optimized dosing design of	116
the host cell membrane	116
the context of a	116
the interaction of the	116
the number of confirmed	116
and pathogenesis of coronaviruses	116
respiratory syndrome coronavirus as	116
of patients from wuhan	116
it is reasonable to	116
one of the first	116
of optimized dosing design	116
chloroquine phosphate has shown	116
on virus entry and	115
among patients with covid	115
and the middle east	115
virus entry and its	115
host response to sars	115
of the virus into	115
in the city of	115
patient with atypical pneumonia	115
of the central nervous	115
associated pneumonia in clinical	115
the safety and efficacy	115
pneumonia in clinical studies	115
the activity of the	115
based on an analysis	115
diagnosis and management of	115
of the most important	115
cluster of cases of	115
of the s subunit	115
lower respiratory tract infections	115
clinical predictors of mortality	115
critically ill icu patients	115
the transmission of the	115
increases the risk of	115
entry and its immune	115
and other respiratory viruses	115
and characteristics of patients	115
been shown to have	114
of the cytokine storm	114
is due to the	114
entry of the virus	114
the declaration of helsinki	114
the time of covid	114
efficacy in treatment of	114
phosphate has shown apparent	114
epidemiological and clinical features	114
are shown in fig	114
that there are no	114
dysregulation of immune response	114
should be considered in	114
is believed to be	114
under the terms of	114
parameters are associated with	114
coronavirus spike protein by	114
pandemic by the world	114
has shown apparent efficacy	114
by the ethics committee	114
the city of wuhan	114
shown apparent efficacy in	114
with the severity of	114
the origin of the	114
and the role of	114
coagulation parameters are associated	114
a patient with atypical	114
infectious diseases society of	114
in intensive care units	114
due to the presence	114
pneumonia after visiting wuhan	113
is possible that the	113
the importance of the	113
of the disease in	113
this is an open	113
was found to have	113
the development of new	113
an analysis of data	113
sars coronavirus spike receptor	113
characterization of spike glycoprotein	113
of the patients had	113
in critically ill icu	113
have not yet been	113
this is consistent with	113
respiratory syndrome in canada	113
the institutional review board	113
type i and type	113
group of the international	113
study group of the	113
with atypical pneumonia after	113
atypical pneumonia after visiting	113
apparent efficacy in treatment	113
it is also important	113
the terms of the	113
for min at room	113
with the help of	113
acute lung injury and	113
are presented in table	113
the antiviral effects of	113
was conducted in the	112
disease caused by the	112
were added to the	112
an urgent need to	112
university of hong kong	112
sars coronavirus spike protein	112
the management of patients	112
it is believed that	112
and adaptive immune responses	112
the acute respiratory distress	112
has been demonstrated that	112
was added to each	112
the development of vaccines	112
as a risk factor	112
terms of the creative	112
the authors have no	112
is the number of	112
vertical transmission of sars	111
during the outbreak of	111
of mortality due to	111
an overview of the	111
when compared to the	111
health care workers in	111
have no conflicts of	111
a mortality rate of	111
at the onset of	111
remains to be determined	111
compassionate use of remdesivir	111
with the development of	111
the first days of	111
hydroxychloroquine in patients with	111
associated with disease severity	111
is also important to	111
acute respiratory syndrome identification	111
the national institute of	111
memory cd t cells	111
diseases society of america	111
thrombotic complications in critically	111
are at higher risk	111
is a potent inhibitor	110
detection of viral rna	110
in hong kong and	110
was admitted to the	110
with sars in the	110
the immune system and	110
of smell and taste	110
in health and disease	110
be used for the	110
could be used as	110
characteristics of patients infected	110
it is interesting to	110
study was supported by	110
there has been a	110
dependent rna polymerase from	110
and its implications for	110
respiratory syndrome identification of	110
the emergence of a	110
in the era of	110
respiratory syndrome coronavirus a	110
were found in the	110
associated with a higher	109
evidence for gastrointestinal infection	109
by the use of	109
the humoral immune response	109
ill icu patients with	109
are similar to those	109
and tumor necrosis factor	109
upper respiratory tract infections	109
s s cleavage site	109
a significant increase in	109
used in the treatment	109
of respiratory syncytial virus	109
the development of the	109
data of patients from	109
and its immune cross	109
respiratory syncytial virus infection	109
viral entry into the	109
it is unclear whether	109
opening remarks at the	109
can be seen in	109
the pathogenesis of severe	109
may be involved in	109
for the identification of	109
our results suggest that	108
all authors contributed to	108
to control the spread	108
analysis of data of	108
of cell entry and	108
of pneumonia of unknown	108
that most of the	108
the impact of sars	108
in the diagnosis of	108
a limited number of	108
be found in the	108
functional assessment of cell	107
a mouse model of	107
assessment of cell entry	107
on the number of	107
of data of patients	107
entry and receptor usage	107
cells were transfected with	107
and clinical course of	107
safety and immunogenicity of	107
in order to avoid	107
h at room temperature	107
and receptor usage for	107
the upper and lower	107
for gastrointestinal infection of	107
close contact with a	107
from publicly reported confirmed	107
a potential target for	107
on the development of	107
disease caused by sars	107
predictors of mortality due	107
clinical characteristics and outcomes	107
cell entry and receptor	107
aim of this study	107
incubation period of coronavirus	107
in viral shedding and	107
inactive inactive inactive inactive	107
from person to person	107
to note that the	107
period of coronavirus disease	107
results showed that the	107
at least one of	106
to be related to	106
dynamics in viral shedding	106
at the active site	106
to an increase in	106
of probable sars cases	106
complete genome sequence of	106
named severe acute respiratory	106
of hydroxychloroquine and azithromycin	106
infected vero e cells	106
gastrointestinal infection of sars	106
for a long time	106
this study was supported	106
neutralizing antibodies against sars	106
a significant number of	106
temporal dynamics in viral	106
viral rna in the	106
in chinese horseshoe bats	106
and transmissibility of covid	106
in relation to covid	106
patients diagnosed with covid	106
an outbreak of severe	106
the respiratory tract of	106
loss of smell and	106
of igm and igg	106
and it has been	106
in the lungs and	106
and the united states	106
the identification of the	106
of receptor recognition by	106
of acute lung injury	106
the entry of sars	106
lower respiratory tract infection	106
initial virological and clinical	106
in patients with cancer	105
role of lopinavir ritonavir	105
an overview of their	105
basis of receptor recognition	105
outbreak of coronavirus disease	105
the respiratory failure of	105
of their replication and	105
on the same day	105
in patients with a	105
sars coronavirus infection and	105
sars in hong kong	105
and angiotensin receptor blockers	105
receptor recognition by sars	105
entry into target cells	105
than that of sars	105
pathogenic coronavirus isolated from	105
to the general population	105
with regard to the	105
added to each well	105
respiratory failure of covid	105
had no role in	105
as a positive control	105
in mice transgenic for	105
overview of their replication	105
natural science foundation of	105
the rbd of sars	105
virological and clinical findings	105
molecular and serological investigation	105
and serological investigation of	105
structural basis of receptor	105
we did not observe	105
of traditional chinese medicine	105
stage of the disease	104
viral shedding and transmissibility	104
article can be found	104
implication of multiple shedding	104
a pandemic by the	104
as the cause of	104
test was used to	104
in children and adolescents	104
authors read and approved	104
and the possibility of	104
airway epithelial cells and	104
is associated with increased	104
of type i interferon	104
was carried out using	104
of patients in the	104
of multiple shedding routes	104
phase of the disease	104
morbidity and mortality in	104
are highly expressed in	104
evolution of coronavirus spike	104
shedding and transmissibility of	104
studies have demonstrated that	104
of patients admitted to	104
and treatment of novel	103
in one of the	103
are natural reservoirs of	103
appears to be a	103
angiotensin i to angiotensin	103
update on the status	103
was estimated to be	103
influenza a and b	103
based dashboard to track	103
of transmission of sars	103
dashboard to track covid	103
with the severe acute	103
media briefing on covid	103
new insights into the	103
of the host cell	103
due to the fact	103
the effects of the	103
of its spike protein	103
plays a key role	103
in the emergency department	103
feline infectious peritonitis virus	103
in the time of	103
receptor binding domain of	103
significant difference in the	102
of the virus is	102
clinical course of patients	102
their replication and pathogenesis	102
patients who did not	102
a cohort of patients	102
clinical features and short	102
the binding free energy	102
outbreak in hong kong	102
bats are natural reservoirs	102
in vitro activity against	102
on the epithelial cells	102
the epidemic and the	102
fatal severe acute respiratory	102
in patients of novel	102
patients with hypertension and	102
the main protease of	102
a short period of	102
in this study was	102
for at least days	102
patients of novel coronavirus	102
on the origin and	102
study clinical features of	102
results suggest that the	102
are at increased risk	102
novel coronavirus outbreak in	102
have been detected in	102
into the host cells	102
and evolution of coronavirus	101
sars in the greater	101
the novel severe acute	101
in the midst of	101
spike glycoprotein of the	101
symptoms such as fever	101
viral load of sars	101
observed in patients with	101
identification and characterization of	101
evolution of the novel	101
active site of the	101
is closely related to	101
term outcomes of patients	101
is related to the	101
patients with suspected or	101
cells in patients with	101
have been identified in	101
descriptive study clinical characteristics	101
more than half of	101
role in the pathogenesis	101
of chest ct and	101
from sars to mers	100
at higher risk for	100
treatment of middle east	100
of interest the authors	100
the european society of	100
chest ct and rt	100
despite the fact that	100
natural reservoirs of sars	100
herpes simplex virus type	100
reproduction in any medium	100
number of patients with	100
severe acute respiratory infections	100
correlation of chest ct	100
use of remdesivir for	100
outbreak of sars in	100
of deceased patients with	100
patients with lung cancer	100
of the present study	100
this article can be	100
and reproduction in any	100
key role in the	100
from sars and mers	100
expression of the sars	100
potential conflicts of interest	100
adult respiratory distress syndrome	100
be associated with the	100
in up to of	100
binding domain of sars	100
with onset of illness	99
pneumonia of unknown etiology	99
the gold standard for	99
the adaptive immune response	99
the cumulative number of	99
the sequence of the	99
systematic reviews and meta	99
infection in patients with	99
the lack of a	99
cells infected with sars	99
a h n virus	99
play a crucial role	99
in order to prevent	99
increased risk for covid	99
are more susceptible to	99
in patients with chronic	99
national natural science foundation	99
case fatality rate of	99
in the central nervous	99
interest the authors declare	99
science foundation of china	99
cell responses to sars	98
the efficacy of the	98
hypertension and diabetes mellitus	98
might be due to	98
is similar to that	98
and respiratory syncytial virus	98
expression of ace receptor	98
is highly expressed in	98
all authors read and	98
those who did not	98
figure a and b	98
provides a basis for	98
human bronchial epithelial cells	98
of chloroquine and hydroxychloroquine	98
and cd t cell	98
onset of illness from	98
was reported to be	98
is a member of	98
reported in the literature	98
a potential conflict of	98
discovery and therapeutic options	98
the virus to the	98
respiratory tract infections in	98
is estimated to be	98
the number of deaths	98
a median of days	98
the spike protein and	98
distribution of severe acute	98
closely related to the	97
research is needed to	97
expression profiling of ace	97
the genome of sars	97
be construed as a	97
more than of the	97
the novel coronavirus pneumonia	97
was performed on the	97
admitted to the intensive	97
the course of covid	97
of vero e cells	97
we also found that	97
research was conducted in	97
is similar to the	97
the clinical features of	97
the number of people	97
of the coronavirus study	97
remdesivir for the treatment	97
with the presence of	97
as part of a	97
acute respiratory syndrome clinical	97
the amino acid sequence	97
acute respiratory syndrome sars	97
for the purpose of	97
therapeutic efficacy of remdesivir	97
could be construed as	97
in adults with severe	97
in a group of	97
the detection of the	97
inhibits the replication of	97
was the most common	97
treatment of critically ill	97
of health care workers	96
commercial or financial relationships	96
detection of sars coronavirus	96
of cases of severe	96
the republic of korea	96
and cellular immune responses	96
in wuhan clinical characteristics	96
potent inhibitor of sars	96
cases with onset of	96
to be effective against	96
is essential for the	96
or financial relationships that	96
remdesivir for patients with	96
severity of coronavirus disease	96
which this version posted	96
fusion of the viral	96
presence of the virus	96
in a number of	96
acute lung injury in	96
in severe coronavirus disease	96
conflict of interest the	96
contamination by severe acute	96
the s s site	96
financial relationships that could	96
of the risk of	96
the coronavirus spike protein	96
respiratory syndrome a novel	96
converting enzyme protects from	96
risk of severe covid	96
the etiological agent of	95
impact of the covid	95
patients infected with covid	95
it remains to be	95
syndrome a novel coronavirus	95
pathogenesis of coronavirus disease	95
probable sars cases with	95
syndrome severe acute respiratory	95
for the production of	95
that could be construed	95
clinical characteristics of deceased	95
cytokines such as il	95
incubated for h at	95
an outbreak of pneumonia	95
characteristics of deceased patients	95
in this study we	95
was considered statistically significant	95
can be used in	95
other lineage b betacoronaviruses	95
study of patients with	95
it has been proposed	95
of remdesivir for patients	95
with the host cell	95
the presence of antibodies	95
ethics committee of the	95
cd t cells were	95
sars cases with onset	95
in health care workers	95
immune responses to sars	95
be attributed to the	95
of t cell responses	94
in the cerebrospinal fluid	94
there are currently no	94
and clinical therapies on	94
as a potential conflict	94
england journal of medicine	94
with hypertension and diabetes	94
all authors have declared	94
used to determine the	94
as the gene source	94
the national institutes of	94
the virus has been	94
to be effective in	94
in a series of	94
o o f journal	94
pathogenesis of severe acute	94
is the most common	94
any commercial or financial	94
the research was conducted	94
tested positive for covid	94
effective in inhibiting sars	94
a human monoclonal antibody	94
antibodies in patients with	94
and severity of covid	94
the gene source of	94
construed as a potential	94
from a symptomatic patient	94
a broad spectrum of	94
epidemiology and pathogenesis of	94
the angiotensin converting enzyme	94
relationships that could be	94
of the general population	94
o f journal pre	94
are considered to be	94
has yet to be	94
of any commercial or	94
wuhan clinical characteristics of	94
summary of probable sars	94
that the presence of	94
absence of any commercial	94
deceased patients with coronavirus	94
there is no specific	94
a significant reduction in	93
it was observed that	93
with novel coronavirus disease	93
assay for the detection	93
as a receptor for	93
proteins of severe acute	93
for h at room	93
admitted to hospital with	93
acute kidney injury in	93
and other lineage b	93
as described in the	93
new england journal of	93
therapies on coronavirus disease	93
available under a perpetuity	93
version of the manuscript	93
antiviral activity against sars	93
the number of covid	93
a vital role in	93
the rbd of the	93
of antibodies against sars	93
of pediatric patients with	93
in close proximity to	93
receptor usage for sars	93
in the lung and	93
in response to sars	93
solid organ transplant recipients	93
clinical therapies on coronavirus	93
onset of symptoms and	93
the integrity of the	93
our results indicate that	93
has been described in	93
a high rate of	93
combination of hydroxychloroquine and	93
is part of the	93
the control of the	93
the management of the	93
that the research was	93
the second week of	93
efficacy of remdesivir and	93
disease is associated with	93
associated with decreased mortality	93
olfactory and gustatory dysfunctions	92
pcr testing in coronavirus	92
respiratory syndrome coronavirus receptor	92
the formation of a	92
study has several limitations	92
testing in coronavirus disease	92
of novel coronavirus infections	92
severe acute lung failure	92
the crystal structures of	92
in acute lung injury	92
have been described in	92
with decreased mortality in	92
and the need for	92
coronaviruses as the gene	92
conducted in the absence	92
transmission and clinical therapies	92
drug discovery and therapeutic	92
in the host cell	92
by the national health	92
at the early stage	92
respiratory syndrome severe acute	92
in an effort to	92
exposure to the virus	92
of t cells in	92
and moderate coronavirus disease	92
severe and moderate coronavirus	92
a basis for design	92
higher in patients with	92
for the control of	92
no significant difference between	92
admitted to intensive care	92
are known to be	92
in the s subunit	92
and pathogenesis of coronavirus	92
and disease severity in	91
is expected to be	91
the host immune system	91
a large proportion of	91
one of the following	91
to the risk of	91
of the severity of	91
been reported in the	91
of morbidity and mortality	91
previous studies have shown	91
and interferon beta against	91
plays a role in	91
equipment contamination by severe	91
the average number of	91
comparative therapeutic efficacy of	91
in the sera of	91
main protease provides a	91
the epidemiology and pathogenesis	91
the course of infection	91
rna was extracted from	91
in critically ill covid	91
we did not find	91
the molecular biology of	91
been identified as a	91
in this study are	91
personal protective equipment contamination	91
in the lower respiratory	91
treatment is associated with	91
a nonhuman primate model	91
remdesivir and combination lopinavir	91
for design of improved	91
the median age was	91
a group of patients	91
interferon beta against mers	91
and discovery of its	91
of remdesivir and combination	91
low molecular weight heparin	91
viral replication in the	91
even in the absence	91
discovery of its inhibitors	90
and potential therapeutic target	90
was found in the	90
highly expressed in nasal	90
have been observed in	90
the detection of viral	90
coronaviridae study group of	90
we were unable to	90
did not receive any	90
the s domain of	90
divergence of the novel	90
clinical and epidemiological features	90
as a negative control	90
the distribution of the	90
can also be used	90
was based on the	90
less toxic derivative of	90
has been demonstrated to	90
pathogenic human coronavirus infections	90
was identified as a	90
a link to the	90
the treatment of the	90
the emergence of the	90
care of patients with	90
protective equipment contamination by	90
patients with severe sars	90
was not detected in	90
protease provides a basis	90
in order to identify	90
there was a significant	90
therapeutic options for the	90
toxic derivative of chloroquine	90
was performed using a	90
of human coronavirus oc	90
during the acute phase	90
of west nile virus	90
characteristics of patients with	90
a less toxic derivative	90
and the severity of	90
were detected in the	90
structural and functional basis	90
in a nonhuman primate	90
of the active site	90
of the presence of	89
the online version of	89
of emerging infectious diseases	89
new york city area	89
innate and adaptive immunity	89
in china clinical characteristics	89
and divergence of the	89
role in the respiratory	89
there was no evidence	89
acute respiratory syndrome severe	89
converting enzyme inhibitors and	89
coronavirus disease in wuhan	89
for the design of	89
with increased risk of	89
play a critical role	89
the spread of infection	89
protein interaction map reveals	89
statistical analysis was performed	89
proportion of patients with	89
version of this article	89
epidemic and the challenges	89
coronavirus severe acute respiratory	89
genome composition and divergence	89
data suggest that the	89
the findings of this	89
among patients hospitalized with	88
in nasal epithelial cells	88
the possibility of a	88
the emerging human coronavirus	88
china epidemiological and clinical	88
the risk of severe	88
of the disease is	88
a novel human coronavirus	88
can be divided into	88
is effective in inhibiting	88
patients in hong kong	88
viral rna mini kit	88
to evaluate the efficacy	88
it is not possible	88
provided the original author	88
is not included in	88
is an open access	88
it is well known	88
creative commons attribution license	88
respiratory syndrome corona virus	88
authors declare that the	88
enzyme inhibitors and angiotensin	88
should be given to	88
dipeptidyl peptidase is a	88
virus in chinese horseshoe	88
syndrome coronavirus envelope protein	88
was one of the	88
in china clinical features	88
as a public health	88
is in line with	88
novel coronavirus from the	88
which may lead to	88
the binding of sars	88
ace is expressed in	88
had at least one	88
injury in patients with	88
was defined as a	88
authors contributed to the	88
at an early stage	88
hydroxychloroquine and azithromycin in	88
in the crystal structure	87
to the onset of	87
mechanisms and potential therapeutic	87
peptidase is a functional	87
in order to reduce	87
a pandemic on march	87
we are grateful to	87
molecular mechanisms and potential	87
h n influenza a	87
patients admitted to hospital	87
by the institutional review	87
respiratory syndrome coronavirus envelope	87
it has been observed	87
encephalitis associated with sars	87
for the emerging human	87
receptor for the emerging	87
cells of oral mucosa	87
the patients in the	87
findings of this study	87
acute respiratory infection when	87
highly expressed in the	87
sars coronavirus infection in	87
the virus that causes	87
may increase the risk	87
in this article are	87
in intensive care unit	87
could be detected in	87
case series of patients	87
of fatal severe acute	87
who have recovered from	87
to the formation of	87
decreased mortality in severe	87
epithelial cells of oral	87
and specificity of the	87
coronavirus in wuhan clinical	87
is associated with severe	87
from human to human	87
and control of the	87
has been used for	86
were excluded from the	86
has been proposed as	86
of the epidemic in	86
cells were treated with	86
mortality in severe coronavirus	86
in order to determine	86
prince of wales hospital	86
inhibitor of sars coronavirus	86
to participate in the	86
duration of viral shedding	86
from symptom onset to	86
it can be seen	86
evidence does not support	86
anticoagulant treatment is associated	86
also found to be	86
cov infection in a	86
with the aim of	86
of cytokine storm and	86
will be important to	86
during the first week	86
on the th day	86
other parts of the	86
first case of meningitis	86
effective treatment of severe	86
the possible role of	86
the function of the	86
the human ace receptor	86
us food and drug	86
lung pathology of fatal	86
of allergy and infectious	86
to the severe acute	86
from severe acute lung	86
the past two decades	86
none of the patients	86
the median time from	86
in the same way	86
the large number of	86
was first identified in	86
pathology of fatal severe	86
inhibitors and angiotensin receptor	86
of smell or taste	86
and functional basis of	85
sars coronavirus spike glycoprotein	85
on the host cell	85
in health care settings	85
with a total of	85
from the united states	85
an increasing number of	85
and indicate if changes	85
were the most common	85
are responsible for the	85
could be used for	85
infections in engineered human	85
in comparison to the	85
like virus in chinese	85
the primary cause of	85
infected with the novel	85
been shown to inhibit	85
is not possible to	85
appropriate credit to the	85
syndrome coronavirus infection in	85
is a lack of	85
provide a link to	85
in patients treated with	85
has been suggested to	85
of ebola virus disease	85
the magnitude of the	85
taking into account the	85
are available from the	85
infectious disease caused by	85
online version of this	85
risk factor for covid	85
according to the who	85
uses the ace receptor	85
has been used in	85
protects from severe acute	85
limit of detection of	85
during the period of	85
patients were treated with	85
is defined as the	85
most of the patients	85
if changes were made	85
patients recovered from covid	85
minimize the risk of	85
in the respiratory failure	85
the length of the	85
to be infected with	85
of ace receptor of	85
in the transmission of	85
cd t cells and	85
clinical evidence does not	85
reduce the number of	85
have a role in	85
indicate if changes were	85
give appropriate credit to	85
in engineered human tissues	85
be detected in the	85
the risk of death	85
of neonates born to	84
risk of human transmission	84
performed according to the	84
the american college of	84
declare that the research	84
is well known that	84
at a higher risk	84
novel coronavirus pneumonia emergency	84
is located in the	84
with a focus on	84
evolution of the sars	84
has been found in	84
associated with increased risk	84
from the onset of	84
china a pneumonia outbreak	84
its spike protein for	84
the s protein and	84
the present study was	84
and is associated with	84
pneumonia in china a	84
a pivotal role in	84
treatment of coronavirus disease	84
engineered human tissues using	84
of nosocomial transmission of	84
coronavirus disease patients with	84
innate immune response to	84
main protease of sars	84
manifestations in patients with	84
patients with severe respiratory	84
syndrome identification of a	84
in the acute phase	84
enzyme protects from severe	84
activates the nlrp inflammasome	84
ministry of health and	84
van doremalen et al	84
from the corresponding author	84
respiratory syndrome coronavirus nsp	84
in the design of	84
ongoing wuhan outbreak and	84
igg and igm antibodies	84
be noted that the	83
from the ongoing wuhan	83
outbreak and modeling of	83
spike protein for risk	83
has not been reported	83
coronavirus pneumonia emergency response	83
a median age of	83
was also observed in	83
n and h n	83
the national natural science	83
influenza a virus infection	83
the ongoing wuhan outbreak	83
severe coronavirus disease patients	83
in the detection of	83
wuhan outbreak and modeling	83
a decrease in the	83
high morbidity and mortality	83
well as in the	83
pneumonia emergency response epidemiology	83
preferred reporting items for	83
a significant proportion of	83
first cases of covid	83
coronavirus open reading frame	83
for rapid detection of	83
compared to that of	83
the involvement of the	83
the s s cleavage	83
characterization of severe acute	83
disease patients with coagulopathy	83
coronavirus from the ongoing	83
protein for risk of	83
response to viral infection	83
modeling of its spike	83
mortality in hospitalized patients	83
for risk of human	83
department of health and	83
clinical features of the	83
for the analysis of	83
and modeling of its	83
there is a lack	83
were used for the	83
the dynamics of the	83
plays a critical role	83
meningitis encephalitis associated with	83
the effectiveness of the	82
of airborne transmission of	82
of a bat sars	82
and control of covid	82
the human respiratory tract	82
as well as their	82
were performed using the	82
that there was no	82
is a risk factor	82
a global health emergency	82
emergence of a novel	82
avian infectious bronchitis virus	82
h n and h	82
increasing the risk of	82
does not support corticosteroid	82
support corticosteroid treatment for	82
reduce the spread of	82
for design of anti	82
functional basis of sars	82
should be taken into	82
national institute of allergy	82
dexamethasone in hospitalized patients	82
grade soluble human ace	82
characteristics of pediatric sars	82
institute of allergy and	82
personal protective equipment for	82
features and clinical course	82
spike protein is a	82
chloroquine is a potent	82
the understanding of the	82
t cell responses in	82
we believe that the	82
case of meningitis encephalitis	82
least one of the	82
study of hydroxychloroquine in	82
disease severity in patients	82
can be considered as	82
the accuracy of the	82
the food and drug	82
of meningitis encephalitis associated	82
infected with the virus	82
the relationship between the	82
therapy in patients with	82
not support corticosteroid treatment	82
entry by using human	82
respiratory syndrome coronavirus entry	82
tumor necrosis factor alpha	82
of the use of	82
to the spread of	81
results of this study	81
there were no significant	81
at high risk for	81
agent of severe acute	81
of patients hospitalized with	81
were similar to those	81
open access article distributed	81
h n avian influenza	81
in the cytoplasm of	81
were shown to be	81
a first case of	81
it is crucial to	81
have been identified as	81
adults with severe covid	81