This is a list of all the questions and their associated study carrel identifiers. One can learn a lot of the "aboutness" of a text simply by reading the questions.
| identifier | question |
|---|---|
| cord-007621-rapinodd | Prehybridization was performed at 42 °(7 in a solution containing 50%( v/ v) formamide, 5 x SSC, 1× Denhardt's solution, 50 p, g/ ml of denatured salmon sperm DNA, and 0.1% sodium dodecyl sulfate( SDS) for 8- 24 h. Hybridization was carried out at 420(` for 48 h in prehybridization solution containing 10% dextran sulfate, 0.05 mM Na phosphate buffer and denatured? |
| cord-013183-t25gecuw | A high plasma concentration of TNF- α is associated with dementia in centenarians C- reactive protein: Risk marker or mediator in atherothrombosis? |
| cord-013803-d1sbfibq | Soluble CD30 serum level- an adequate marker for allograft rejection of solid organs? |
| cord-005664-n4xv247l | The acute respiratory distress syndrome Ventilator- induced lung inflammation: is it always harmful? |
| cord-005664-n4xv247l | a contributing factor? |
| cord-003013-h8txbd3p | Bacteria, the endoplasmic reticulum and the unfolded protein response: friends or foes? |
| cord-003013-h8txbd3p | LRRK2 enhances Nod1/2-mediated inflammatory cytokine production by promoting Rip2 phosphorylation IL-1β processing in host defense: beyond the inflammasomes Dysregulated IL-1β secretion in autoinflammatory diseases: a matter of stress? |
| cord-006610-me8rhkcg | How do they survive in this hostile environment and sustain tumor neovascularization? |
| cord-006610-me8rhkcg | What is the role of endothelial cells in angiogenesis? |
| cord-000324-to4g9he9 | Is Panton- Valentine leukocidin the major virulence determinant in community- associated methicillin- resistant Staphylococcus aureus disease? |
| cord-000324-to4g9he9 | Repeated injection of MK801: an animal model of schizophrenia? |
| cord-001293-dfaxj3bv | Are patients with sepsis dying of immune failure-dissecting the arguments used to describe compensatory immunosuppression occurring after sepsis? |
| cord-001293-dfaxj3bv | Is boosting the immune system in sepsis appropriate? |
| cord-001293-dfaxj3bv | authors: Cavaillon, Jean- Marc; Eisen, Damon; Annane, Djilalli title: Is boosting the immune system in sepsis appropriate? |
| cord-007613-g4s0v8ra | Cytokines and HIV infection: is AIDS a tumour necrosis factor disease? |
| cord-002209-xs6qigg4 | Astrocyte activation( mild astrogliosis): a pro- reparative phenotype? |
| cord-002209-xs6qigg4 | The impact of astrocytic gap junctional coupling on potassium buffering in the hippocampus Distinct stages of myelination regulated by gamma- secretase and astrocytes in a rapidly myelinating CNS coculture system Immunocytochemical study of myelinassociated glycoprotein( MAG), basic protein( BP), and glial fibrillary acidic protein( GFAP) in chronic relapsing experimental allergic encephalomyelitis( EAE) Astrocytes- friends or foes in multiple sclerosis? |
| cord-002209-xs6qigg4 | The interleukin 1 receptor: ligand interactions and signal transduction Myelination: do astrocytes play a role? |
| cord-003686-1pfk4qve | Safety profile of the interleukin-1 inhibitors anakinra and canakinumab in real- life clinical practice: a nationwide multicenter retrospective observational study Fluorouracil and bevacizumab plus anakinra for patients with metastatic colorectal cancer refractory to standard therapies( IRAFU): a single- arm phase 2 study Interleukin-1 Beta- a friend or foe in malignancies? |
| cord-003686-1pfk4qve | the legendary fifth cardinal sign of inflammation, added by Galen to the four cardinal signs of Celsus Robbins& Cotran pathologic basis of disease Inflammation and metabolic disorders Endoplasmic reticulum stress and the inflammatory basis of metabolic disease Inflammatory mechanisms in obesity Approaching the asymptote? |
| cord-005872-w1x1i0im | Does elevated nitric oxide production enhance the release of prostacyclin from shear stressed aortic endothelial cells? |
| cord-005872-w1x1i0im | To block or enhance its production during sepsis? |
| cord-023950-nv0pbbu2 | A Risk or Advantage? |
| cord-006770-m5wqk6rh | Should we conclude that the treatment of infectious disease with TNF will be impossible, in spite of the conclusive evidence that this cytokine is an essential part of the normal response to infection? |
| cord-006770-m5wqk6rh | The malaria vaccine: anti- parasite or anti- disease? |
| cord-006770-m5wqk6rh | The role of cytokines in the immunopathology of tuberculosis and the regulation of agalactosyl IgG TNF as an activator of vascular endothelium Does tumor necrosis factor play a role in the pathogenesis of fulminant hepatitis? |
| cord-006828-i88on326 | -was hat sich verändert? |
| cord-006828-i88on326 | Aktivitätsmarker der Lupusnephritis? |
| cord-006828-i88on326 | Komplementmangels ist bisher nicht untersucht( andere Bestandteile der Kaskade?) |
| cord-262511-96xp1v0r | ARED 3.0: the large and diverse AU- rich transcriptome AU- rich elements and associated factors: are there unifying principles? |
| cord-262511-96xp1v0r | Can the RNA decay- promoting activity of the RNA- binding proteins be harnessed as an antiviral therapeutic strategy? |
| cord-006518-al94gxjw | Definitions for Sepsis and Organ Failure and Guidelines for the Use of Innovative Therapies in Sepsis Strategies for the Treatment of Sepsis Epidemiology of Severe Sepsis in the United States: Analysis of Incidence, Outcome, and Associated Costs of Care Has the Mortality of Septic Shock Changed with Time? |
| cord-006518-al94gxjw | Genetically Determined by TNF- β NcoI Gene Polymprophism? |
| cord-006518-al94gxjw | Pouring Oil on Troubled Waters or Another Fishy Tale? |
| cord-006518-al94gxjw | Should Immunonutrition Become Routine in Critically Ill Patients? |
| cord-015147-h0o0yqv8 | Here we report on the development of the PGE2 mimetic combination therapy( DP-837953) that inhibits basal and LPS/ TLR4 induced TNF-?, IL-1ß, and MMP-1, 8, 9, 13 in human and murine synovial membranes and peripheral macrophages. |
| cord-015147-h0o0yqv8 | In a murine model of chronic synovitis( dorsal skin air pouch), DP837953 dramatically inhibited IL-1ß, TNF-?, MIP2, MCP-2 and IL-8 expression, delayed the profile of leukocyte/ neutrophil extravasation and reduced exudate volume. |
| cord-015147-h0o0yqv8 | In addition, TNF-?, IL-1ß, MMP-8 and to a lesser extent MMP-9 expression/ synthesis levels were strongly suppressed as judged by RT- PCR and ELISA measurements |
| cord-015147-h0o0yqv8 | Most of the recent studies have focused on challenge- induced expression of antimicrobial peptides and have addressed the following questions:( 1) which genes are upregulated during various types of bacterial, fungal or viral infections and what are their functions? |
| cord-022353-q2k2krnm | A mouse bleeding technique yielding consistent volume with minimal hemolysis Transgenesis and the study of expression, cellular targeting, and function of oxytocin, vasopressin and their receptors KOs model the 100 best- selling drugs: will they model the next 100? |
| cord-022353-q2k2krnm | Insights in asthma from overexpression transgenic modeling Genotype, obesity, and cardiovascular disease: has technical and social advance outstripped evolution? |
| cord-022353-q2k2krnm | Mildly oxidized LDL induces an increase apolipoprotein J/ paraoxonase ration The genetic control of alkaline phosphatase activity in the duodenum of the mouse Diabetes mellitus: a"thrifty"genotype rendered detrimental by"progress"? |
| cord-022353-q2k2krnm | The protein profile of acetazolamidetreated sera in mice bearing Lewis neoplasm CEBS object modes for systems biology data, SysBio- OM Partal hormone resistance in mice with disruption of the steroid receptor coactivator-1( SRC-1) gene Platelet factor 4 gene transfection into tumor cells inhibits angrogenesis tumor growth and metastasis Mice lacking the thyrotropin- releasing hormone gene: what do they tell us? |
| cord-276564-o21ncldx | Why Does COVID-19 Disproportionately Affect the Elderly? |
| cord-023935-o2ffxgnn | In monitoring her response to these interventions, which of the following should NOT be used as a therapeutic endpoint to monitor her progress? |
| cord-023935-o2ffxgnn | There is suffi cient data to justify the use of which of the following adjuvant therapies in pediatric sepsis? |
| cord-023935-o2ffxgnn | Which of the following components of coagulation is increased during sepsis? |
| cord-017309-pt27efu1 | Does colorectal cancer clinical advancement affect adhesion molecules( sP- selectin, sE- selectin and ICAM-1) concentration? |
| cord-017309-pt27efu1 | I( s- VCAM- I) and soluble intercellular adhesion molecule- I( s- ICAM- I) levels in bladder carcinoma patients with different stages Autoantibodies and other serological markers in rheumatoid arthritis: predictors of disease activity? |
| cord-017309-pt27efu1 | The antitumor activity of an anti- CD54 antibody in SCID mice xenografted with human breast, prostate, non- small cell lung, and pancreatic tumor cell lines Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E- selectin and P- selectin double mutant mice Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress Invasive amebiasis: A microcirculatory disorder? |
| cord-017309-pt27efu1 | The impact of peripheral arterial disease on circulating platelets Intestinal inflammation in adhesion molecule- deficient mice: an assessment of P- selectin alone and in combination with ICAM-1 or E- selectin Adhesion molecule polymorphisms in chronic renal allograft failure Endothelial adhesion molecules are associated with inflammation in subjects with HIV disease Evaluation of microbiologic and hematologic parameters and E- selectin as early predictors for outcome of neonatal sepsis Expression of endothelial protein C receptor and thrombomodulin in human coronary atherosclerotic plaques P- selectin in arterial thrombosis Role of ICAM-1 in persisting inflammation in Parkinson disease and MPTP monkeys Cellular adhesion molecules and blood pressure: interaction with sex in a multi- ethnic population Association between the Thr715Pro P- selectin gene polymorphism and soluble P- selectin levels in a multiethnic population in South London Effect of clopidogrel on the expression of inflammatory markers in rabbit ischemic coronary artery Allergic rhinitis: continuous or on demand antihistamine therapy? |
| cord-017309-pt27efu1 | The levels of soluble adhesion molecules in diabetic and nondiabetic patients with combined hyperlipoproteinemia and the effect of ciprofibrate therapy Increased platelet activation markers in rheumatoid arthritis: are they related with subclinical atherosclerosis? |
| cord-017470-sjk7a34u | But who is the conductor? |
| cord-017470-sjk7a34u | Pulmonary edema Is the mortality higher in the pulmonary vs the extrapulmonary ARDS? |
| cord-017470-sjk7a34u | The lingering consequences of sepsis: the hidden public health disaster? |
| cord-017470-sjk7a34u | a systematic review Glucocorticoids potently block tumor necrosis factor- alpha and lipopolysaccharide- induced apoptotic cell death in bovine glomerular endothelial cells upstream of caspase 3 activation Renal blood flow distribution in experimental septic acute renal failure Pathophysiology of septic acute kidney injury: what do we really know? |
| cord-017470-sjk7a34u | following a brief exposure to endotoxin: a mechanism to link infection and infarction? |
| cord-017470-sjk7a34u | paradigms lost? |
| cord-018764-02l423mk | As outlined in the section'Is hyperlactataemia a cause or marker of the acidosis of malaria?' |
| cord-018764-02l423mk | Possible central role of nitric oxide in conditions clinically similar to cerebral malaria Nitric oxide potently and reversibly deenergizes mitochondria at low oxygen tension Tumor necrosis factor- alpha and lipopolysaccharide enhance interferoninduced antichlamydial indoleamine dioxygenase activity independently Lipopolysaccharide induction of indoleamine 2,3-dioxygenase is mediated dominantly by an IFN- gamma- independent mechanism Metabolites of the kynurenine pathway of tryptophan metabolism in the cerebrospinal fluid of Malawian children with malaria Cerebrospinal fluid studies in children with cerebral malaria: An excitotoxic mechanism? |
| cord-018764-02l423mk | Reevaluation of the role of cellular hypoxia and bioenergetic failure in sepsis Does tissue acidosis in sepsis indicate tissue hypoperfusion? |
| cord-018764-02l423mk | The effect of intravenous lactate on cerebral function during hypoglycaemia Lactate as a pivotal element in neuron- glia metabolic cooperation Unaccounted for anion in metabolic acidosis during severe sepsis in humans Unmeasured anions identified by the Fencl- Stewart method predict mortality better than base excess, anion gap, and lactate in patients in the pediatric intensive care unit Unidentified acids of strong prognostic significance in severe malaria Glucose homeostasis in children with falciparum malaria: precursor supply limits gluconeogenesis and glucose production Hypoglycemia as a manifestation of sepsis Hypoglycaemia is an important complication of falciparum malaria Severe falciparum malaria Intracranial pressure in childhood cerebral malaria Intracranial hypertension in Africans with cerebral malaria Prognostic significance and course of retinopathy in children with severe malaria Blood- brain barrier in falciparum malaria Breaking down the blood- brain barrier: signaling a path to cerebral malaria? |
| cord-018764-02l423mk | The injured child is resistant to multiple organ failure: a different inflammatory response? |
| cord-018764-02l423mk | where do they come from; where do they go to? |
| cord-002119-kl431ev6 | ( SK2) modulates hippocampal learning, memory, and synaptic plasticity Calcium signalling: dynamics, homeostasis and remodelling Local calcium signaling in neurons Remyelination after spinal cord injury: is it a target for repair? |
| cord-002119-kl431ev6 | CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system Protective autoimmunity: regulation and prospects for vaccination after brain and spinal cord injuries B cell selection and susceptibility to autoimmunity Human innate B cells: a link between host defense and autoimmunity? |
| cord-002119-kl431ev6 | CXCL10 enhances tissue sparing and angiogenesis following spinal cord injury Cellular inflammatory response after spinal cord injury in Sprague- Dawley and Lewis rats Macrophage activation and its role in repair and pathology after spinal cord injury Rats and mice exhibit distinct inflammatory reactions after spinal cord injury Neuroprotection and acute spinal cord injury: a reappraisal Astrocyte roles in traumatic brain injury Microglia and inflammation: conspiracy, controversy or control? |
| cord-002119-kl431ev6 | Do chemokines mediate inflammatory cell invasion of the central nervous system parenchyma? |
| cord-002119-kl431ev6 | Is neuroinflammation in the injured spinal cord different than in the brain? |
| cord-002119-kl431ev6 | an immunohistochemical study GeneChip5 analysis after acute spinal cord injury in rat Activated human T cells, B cells, and monocytes produce brain- derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation? |
| cord-006444-eq56zhtd | 10 patients showed antitumor response to immunotherapy: 3 complete remissions( CR) and? |
| cord-006444-eq56zhtd | Are the growth factors simply permissive for these processes? |
| cord-006444-eq56zhtd | Or do they have an inductive role to play in lineage commitment of stem cells and subsequent maturation into phenotypically mature cells? |
| cord-006444-eq56zhtd | The number of activated T- cells defined by the antigens CD38, HLA- DR and CD56 were low or in the normal range, and did not fu~ er decrease during therapy in contrast to the non- activated T- cells.? |
| cord-006444-eq56zhtd | W41/88/ Ha-1- 2 from the Deutsche Krebshilfe and 90.055.1 from the Withe~ m- Sander Stiftung IS GRANULOCYTE COLONY- STIMULATING FACTOR AN ANGIOGENIC FACTOR IN HUMAN GLIOBLASTOMA? |
| cord-006444-eq56zhtd | the high- dose chemotherapy consisted of prednisolone 60rag/ n? p.o. |
| cord-016523-pznw2ciu | +-dependent molecular mechanisms transiently inhibiting DISC formation, and do tumor cells use this signal to escape the immune response and/or resist chemotherapy? |
| cord-016523-pznw2ciu | Cancer immunosurveillance, immunoediting and infl ammation: independent or interdependent processes? |
| cord-016523-pznw2ciu | Cisplatin- induced CD95 redistribution into membrane lipid rafts of HT29 human colon cancer cells Redistribution of CD95 into the lipid rafts to treat cancer cells? |
| cord-016523-pznw2ciu | Does CD95 have tumor promoting activities? |
| cord-016523-pznw2ciu | Oncogenic Cytokine? |
| cord-016523-pznw2ciu | inhibits programmed necrosis by processing CYLD Programmed cell death: apoptosis meets necrosis Fas involvement in cytotoxicity mediated by human NK cells Fas ligand expression by astrocytoma in vivo: maintaining immune privilege in the brain? |
| cord-023425-3sjsogvq | Necrosis Factor‐α Responders Exist in Dairy Cows? |
| cord-004879-pgyzluwp | A50$ 14- 28 Neutralization rates of TNF- a from eight animal species by a monoclonal antibody against human TNF: implication for receptor action? |
| cord-004879-pgyzluwp | Are these two activities encoded by a single mRNA? |
| cord-004879-pgyzluwp | Do their protein- chemical structure and organisation decipher us certain clues and parts of the path by which they have been selected and derived from a possible primordial reaction centre polypeptide? |
| cord-004879-pgyzluwp | Does the ALEP1 germ- line specific protein have a homologue in the somatic ribosomes? |
| cord-004879-pgyzluwp | However, in the presence of 1000 U/ ml interferon? |
| cord-004879-pgyzluwp | Is membranebound enzyme preferentially associated with a given cellular membrane? |
| cord-004879-pgyzluwp | What is the function of rpS 19? |
| cord-017640-i8h48ny6 | +-dependent molecular mechanisms transiently inhibiting DISC formation, and do tumor cells use this signal to escape the immune response and/or resist chemotherapy? |
| cord-017640-i8h48ny6 | Cancer immunosurveillance, immunoediting and inflammation: independent or interdependent processes? |
| cord-017640-i8h48ny6 | Cisplatin- induced CD95 redistribution into membrane lipid rafts of HT29 human colon cancer cells Redistribution of CD95 into the lipid rafts to treat cancer cells? |
| cord-017640-i8h48ny6 | Does CD95 have tumor promoting activities? |
| cord-017640-i8h48ny6 | Mutations? |
| cord-017640-i8h48ny6 | Oncogenic Cytokine? |
| cord-017640-i8h48ny6 | inhibits programmed necrosis by processing CYLD Programmed cell death: apoptosis meets necrosis Fas involvement in cytotoxicity mediated by human NK cells Fas ligand expression by astrocytoma in vivo: maintaining immune privilege in the brain? |
| cord-017520-r786yd6i | Circulating postinjury neutrophils are primed for the release of proinflammatory cytokines Elevated levels of soluble ICAM-1 correlate with the development of multiple organ failure in severely injured trauma patients Cytokines and adhesion molecules in elective and accidental trauma- related ischemia/ reperfusion Molecular mechanics and dynamics of leukocyte recruitment during inflammation Trauma- induced suppression of antigen presentation and expression of major histocompatibility class II antigen complex in leukocytes Direct bacterial protein PAMP recognition by human NK cells involves TLRs and triggers alpha- defensin production NK cell recognition Augmentation of NK cell activity by a circulating peptide isolated from the plasma of trauma patients Natural killer cells as an initial defense against pathogens Mechanism of suppression of natural killer cell activity in trauma patients Depletion of NK cells in a murine polytrauma model is associated with improved outcome and a modulation of the inflammatory response The role of natural killer cells in sepsis Natural killer cells contribute to the lethality of a murine model of Escherichia coli infection Inflammation in traumatic brain injury: role of cytokines and chemokines Modulation of immune response by head injury Closed head injury- an inflammatory disease? |
| cord-017520-r786yd6i | Early expression changes of complement regulatory proteins and C5A receptor( CD88) on leukocytes after multiple injury in humans Complement: more than a'guard'against invading pathogens? |
| cord-017520-r786yd6i | Early onset of lipid peroxidation after human traumatic brain injury: a fatal limitation for the free radical scavenger pharmacological therapy? |
| cord-017520-r786yd6i | Evidence for a role of kallikrein- P6nin system in patients with shock after blunt trauma Formation of bradykinin: a major contributor to the innate inflammatory response Molecular intercommunication between the complement and coagulation systems Is interleukin 6 an early marker of injury severity following major trauma in humans? |
| cord-017520-r786yd6i | Increased neutrophil migratory activity after major trauma: a factor in the etiology of acute respiratory distress syndrome? |
| cord-017520-r786yd6i | Marker of injury or mediator of inflammation? |
| cord-017520-r786yd6i | The gut: the'motor'of multiple organ dysfunction syndrome? |
| cord-256837-100ir651 | how does HIV-1 exacerbate tuberculosis? |
| cord-270414-gh9agf4x | What's new? |
| cord-271114-hv3gwvdi | -174 genotype associated with the development of septicemia in preterm infants? |
| cord-271114-hv3gwvdi | Genetic predisposition of the interleukin-6 response to inflammation: implications for a variety of major diseases? |
| cord-271114-hv3gwvdi | The relationship between hospital spending and mortality in patients with sepsis 4 million neonatal deaths: when? |
| cord-271114-hv3gwvdi | Where? |
| cord-271114-hv3gwvdi | Why? |
| cord-023928-9a1w174h | Given the tens of thousands of genes in the human genome and the millions of genetic polymorphisms, on which polymorphisms and in which genes should investigators focus? |
| cord-023928-9a1w174h | I LLN ESS severity between two children with pneumonia be associated with variations in their genes coding for one of the surfactant proteins? |
| cord-023928-9a1w174h | In considering this possibility, which of the following is true? |
| cord-295523-5pv7kw6i | Still's disease and catastrophic antiphospholipid syndrome triggered by fulminant Chikungunya infection: A case report of two patients Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway Regulation of ferritin genes and protein Hyperferritinemia in the critically ill child with secondary hemophagocytic lymphohistiocytosis/ sepsis/ multiple organ dysfunction syndrome/ macrophage activation syndrome: What is the treatment? |
| cord-295523-5pv7kw6i | The association between systemic glucocorticoid therapy and the risk of infection in patients with rheumatoid arthritis: Systematic review and meta- analyses Long- term anti- TNF therapy and the risk of serious infections in a cohort of patients with rheumatoid arthritis: Comparison of adalimumab, etanercept and infliximab in the GISEA registry Long- term safety of abatacept in patients with rheumatoid arthritis Adverse effects of biologics: A network meta- analysis and Cochrane overview Influenza vaccination in systemic lupus erythematosus: Safe and protective? |
| cord-271812-ldwb05xn | What causes Alzheimer's? |
| cord-278339-6ddsj014 | The risk of infections associated with rheumatoid arthritis, with its comorbidity and treatment a rush to judgment? |
| cord-278339-6ddsj014 | What is the true incidence of COViD-19 in patients with rheumatic diseases? |
| cord-259586-kep2dgaw | Finally, we can study some of the most exciting questions in pigs, such as: How do viruses induce the production of different cytokines? |
| cord-259586-kep2dgaw | How do cytokines released in the lung exert systemic effects? |
| cord-259586-kep2dgaw | Which cells make cytokines during different virus infections and where? |
| cord-280599-7ixpqd5n | So, what can we expect to learn by profiling cytokine production or levels in blood samples from patients with inflammatory diseases? |
| cord-280599-7ixpqd5n | What does the peripheral blood tell you in SARS? |
| cord-291076-p350i54m | Neutrophil extracellular traps: is immunity the second function of chromatin? |
| cord-291076-p350i54m | The Middle East respiratory syndrome-- how worried should we be? |
| cord-306577-gq6fss5l | A relation between localization and function? |
| cord-306577-gq6fss5l | Necrotizing enterocolitis in very low birth weight infants: biodemographic and clinical correlates Very low birth weight outcomes of the National Institute of Child Health and Human Development neonatal network Necrotizing enterocolitis- multisystem organ failure of the newborn? |
| cord-309619-glb2y82u | The antithrombotic effect of angiotensin-(1- 7) involves mas- mediated NO release from platelets High frequency of antiphospholipid antibodies in critically- ill COVID-19 patients: a link with hypercoagulability? |
| cord-309619-glb2y82u | risk factors in medical- surgical critically ill patients* multicenter study; randomized controlled trial Pulmonary thrombosis: a clinical pathological entity distinct from pulmonary embolism? |
| cord-309619-glb2y82u | rs12252-C is associated with disease severity in COVID-19 Genomewide Association study of severe Covid-19 with respiratory failure Use of reninÀangiotensinÀaldosterone system inhibitors and risk of COVID-19 requiring admission to hospital: a case- population study Novel antibody epitopes dominate the antigenicity of spike glycoprotein in SARS- CoV-2 compared to SARS- CoV Soluble angiotensin- converting enzyme 2: a potential approach for coronavirus infection therapy? |
| cord-307813-elom30nx | A decoy peptide that disrupts TIRAP recruitment to TLRs is protective in a murine model of influenza Novel strategies for targeting innate immune responses to influenza Highly pathogenic avian influenza A H5N1 and pandemic H1N1 virus infections have different phenotypes in toll- like receptor 3 knockout mice Inhibition of toll- like receptor signaling as a promising therapy for inflammatory diseases: a journey from molecular to nano therapeutics Small- molecule inhibitors of the TLR3/ dsRNA complex Radix isatidis polysaccharides inhibit influenza a virus and influenza A virus- induced inflammation via suppression of Host TLR3 signaling in vitro Novel effect of methionine enkephalin against influenza A virus infection through inhibiting TLR7-MyD88-TRAF6-NF- kappaB p65 signaling pathway Influenza virus and glycemic variability in diabetes: a killer combination? |
| cord-307813-elom30nx | Innate lymphoid cells in asthma: will they take your breath away? |
| cord-307813-elom30nx | a mechanism for the unusual severity of human disease? |
| cord-034340-3ksfpaf7 | Before making a definitive diagnosis of HLH patients were treated for PUO, sepsis? |
| cord-034340-3ksfpaf7 | None declared AB041 Paediatric extra- pulmonary large vessel arteritis, a forme fruste of pediatric Behcet's disease? |
| cord-313227-6zwkfzab | An overview on medicinal perspective of thiazolidine-2,4-dione: a remarkable scaffold in the treatment of type 2 diabetes TNF- alpha and inflammatory cytokines and risk of type 2 diabetes: a systematic review and meta- analysis Selective insulin resistance and the development of cardiovascular diseases in diabetes: the 2015 edwin bierman award lecture Can pioglitazone be potentially useful therapeutically in treating patients with COVID-19? |
| cord-313227-6zwkfzab | are we already that far? |
| cord-306983-6w2fvtfy | Influenza A virus associated with acute encephalopathy PCR on cerebrospinal fluid to show influenza- associated acute encephalopathy or encephalitis Systemic cytokine responses in patients with influenza- associated encephalopathy Induction of proinflammatory cytokines in human macrophages by influenza A( H5N1) viruses: a mechanism for the unusual severity of human disease? |
| cord-310942-191m0e65 | Russel J. title: Beneficial actions of melatonin in the management of viral infections: a new use for this “ molecular handyman ”? |
| cord-336432-tu00gffr | Can we trust docking results? |
| cord-336432-tu00gffr | China Is it reliable to take the molecular docking top scoring position as the best solution without considering available structural data? |
| cord-319121-et957lfl | What's behind the decline? |
| cord-317628-1inxq7t5 | What Are We Talking About? |
| cord-351310-6p42b144 | What's new? |
| cord-301946-erzh30mt | American journal of physiology Could intravenous immunoglobulin collected from recovered coronavirus patients protect against covid-19 and strengthen the immune system of new patients? |
| cord-301946-erzh30mt | Archives of gynecology and obstetrics Lymphocyte immunotherapy for recurrent miscarriages: Predictors of therapeutic success Information for clinicians on therapeutic options for covid-19 patients Clinical and immunologic features in severe and moderate coronavirus disease 2019 Tumor necrosis factor Chloroquine and hydroxychloroquine as available weapons to fight covid-19 A systematic review on the efficacy and safety of chloroquine for the treatment of covid-19 Does immunotherapy for treatment of reproductive failure enhance live births? |
| cord-301946-erzh30mt | Intravenous immunoglobulin therapy: How does igg modulate the immune system? |
| cord-301946-erzh30mt | What to expect for covid-19? |
| cord-301946-erzh30mt | a th2 phenomenon? |
| cord-301946-erzh30mt | china Hfea coronavirus( covid-19) guidancecurrent status as of Covid-19 and vitamin d- is there a link and an opportunity for intervention? |
| cord-351387-i0zamkpd | Phytomedicine Cutting edge: immune cells as sources and targets of the IL-10 family members? |
| cord-341667-ayl71jpc | Interferon- α, Tumor Necrosis Factor- α, Interleukin-1, and Inflammation during Acute Influenza in Pigs: A Possible Model for Humans? |
| cord-295745-iw3ftw3h | The Croonian Lecture Part of a scientific master plan? |
| cord-295745-iw3ftw3h | This not only demonstrates the involvement of TNF in the progression to colon cancer but also the potency of its decoy in treatment Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis Anti- angiogenesis: new concept for therapy of solid tumors Angiogenesis: an organizing principle for drug discovery? |
| cord-337414-8ndkjs1i | immune system molecule expression in the central nervous system Bcl-2 and the regulation of programmed cell death OLN-93: a new permanent oligodendroglia cell line derived from primary rat brain glial cultures Oligodendroglial degeneration in distemper: apoptosis or necrosis? |
| cord-354492-6r6qs4pp | The effects of diets enriched in omega-3 polyunsaturated fatty acids on systemic vaccinia virus infection Omega-3 polyunsaturated fatty acids and inflammatory processes: Nutrition or pharmacology? |
| cord-354492-6r6qs4pp | What next? |
| cord-316904-g7dli0a8 | 112 Is there a role for leptin? |
| cord-316904-g7dli0a8 | As these cytokines do not appear to cross the blood- brain barrier in significant amounts, how can these cytokines be acting at the CNS level? |
| cord-316904-g7dli0a8 | What are mechanisms( and mediators) by which anorexia and hypermetabolism are produced? |
| cord-316904-g7dli0a8 | What, therefore, would be the cause for muscle wast- ing in AIDS? |
| cord-316904-g7dli0a8 | pilot studies Pentoxifylline therapy in HIV seropositive subjects with elevated TNF Pentoxifylline for treatment of cancer anorexia and cachexia? |
| cord-353887-f4yd7guj | Intravenous immunoglobulin therapy: how does IgG modulate the immune system? |
| cord-353887-f4yd7guj | the Guangzhou experience Potential benefits of precise corticosteroids therapy for severe 2019-nCoV pneumonia Decoding the enigma of antiviral crisis: does one target molecule regulate all? |
| cord-340741-bhxm4zua | How good is automated protein docking? |
| cord-340741-bhxm4zua | why today? |
| cord-300991-ipy24zxp | 2020, 9, x FOR PEER REVIEW 4 of 12 buds or nasal mucosal epithelia? |
| cord-300991-ipy24zxp | A Sixth Taste Modality? |
| cord-300991-ipy24zxp | COVID-19 patients not exhibit a change in ONS perception? |
| cord-300991-ipy24zxp | Can the strategies to alter the intestinal microbiota decrease the severity of SARS- CoV-2 infection? |
| cord-300991-ipy24zxp | Does SARS- CoV-2 infect taste buds or nasal mucosal epithelia? |
| cord-300991-ipy24zxp | Does this viral infection promote a particular microbiome in the gut and ONS epithelia? |
| cord-300991-ipy24zxp | Is there any genetic or epigenetic predisposition? |
| cord-300991-ipy24zxp | all the COVID-19 subjects not complain of the loss of smell? |
| cord-336510-qzm9wgde | NF- kappa B induction of major histocompatibility class I and beta 2-microglobulin gene expression in transfected human neuroblastoma cells Complex formation of the interferon( IFN) consensus sequence- binding protein with IRF-1 is essential for murine macrophage IFN- gamma- induced iNOS gene expression Does nitric oxide play a critical role in viral infections? |
| cord-336510-qzm9wgde | NO or no NO? |
| cord-336510-qzm9wgde | The acquisition of herpes simplex virus during pregnancy Neonatal herpes simplex virus infection in relation to asymptomatic maternal infection at the time of labor Herpes simplex virus infections of women and their offspring: implications for a developed society Neonatal herpes simplex virus infections: is there a role for immunoglobulin in disease prevention and therapy? |
| cord-336510-qzm9wgde | interferon- beta mRNA levels in human fibroblasts Is Wiskott- Aldrich syndrome a cell trafficking disorder? |
| cord-022526-j9kg00qf | , why does the iced tea have a garlic taste? |
| cord-022526-j9kg00qf | : what happens in the microcompartments? |
| cord-022526-j9kg00qf | How important is intestinal reperfusion injury in horses? |
| cord-022526-j9kg00qf | Is Helicobacter( Campylobacter) pylori associated with gastritis/ ulcer disease in asymptomatic foals? |
| cord-022526-j9kg00qf | The oral glucose tolerance test in the horse Small intestinal malabsorption in the horse: an assessment of the specificity of the oral glucose tolerance test Transient glucose malabsorption in two horses: fact or artifact? |
| cord-022526-j9kg00qf | The role of cyclooxygenase inhibitors in repair of ischaemic- injured jejunal mucosa in the horse Mechanisms of acute and chronic intestinal inflammation induced by indomethacin Mechanisms of NSAID- induced gastrointestinal injury defined using mutant mice Pathogenesis of NSAID gastropathy: are neutrophils the culprits? |
| cord-354765-abayh871 | Innate immune response to viral infection Mechanisms and Therapeutic Relevance of Neuro- immune Communication Acute respiratory failure in COVID-19: is it"typical"ARDS? |
| cord-354765-abayh871 | Peripheral Focused Ultrasound Stimulation( pFUS): New Competitor in Pharmaceutical Markets? |
| cord-354765-abayh871 | Revisited Storm, typhoon, cyclone or hurricane in patients with COVID-19? |
| cord-348855-lnltoj1n | : what to expect for COVID-19? |
| cord-348855-lnltoj1n | Could Intravenous Immunoglobulin Collected from Recovered Coronavirus Patients Protect against COVID-19 and Strengthen the Immune System of New Patients? |
| cord-348855-lnltoj1n | Should we stimulate or suppress immune responses in COVID-19? |
| cord-348855-lnltoj1n | should inhibitors of the reninangiotensin system be withdrawn in patients with COVID-19? |
| cord-348391-xytmq2f2 | Are they closely related? |
| cord-348391-xytmq2f2 | Characteristics of pediatric SARS- CoV-2 infection and potential evidence for persistent fecal viral shedding The immunology of COVID-19: Is immune modulation an option for treatment? |
| cord-348391-xytmq2f2 | Recombination and complementation between orthomyxoviruses under conditions of abortive infection Why is the flu vaccine so mediocre? |
| cord-348391-xytmq2f2 | The mechanism of cell death during West Nile virus infection is dependent on initial infectious dose Mechanism of cell death during infectious salmon anemia virus infection is cell type- specific Dengue virus infection induces passive release of high mobility group box 1 protein by epithelial cells Systemic release of high mobility group box 1 protein during severe murine influenza HMG-1 as a Late Mediator of Endotoxin Lethality in Mice Pathogenic role of HMGB1 in SARS? |
| cord-348391-xytmq2f2 | Why do RNA viruses recombine? |
| cord-016960-xhzvp35g | ( 2007)? |
| cord-016960-xhzvp35g | (, 2005? |
| cord-016960-xhzvp35g | : where does it come from? |
| cord-016960-xhzvp35g | Does the use of tumour necrosis factor antagonist therapy in poor prognosis, undifferentiated arthritis prevent progression to rheumatoid arthritis? |
| cord-016960-xhzvp35g | The biology of VEGF and its receptors Development of ranibizumab, an antivascular endothelial growth factor antigen binding fragment, as therapy for neovascular agerelated macular degeneration Clinical and immune responses in resected colon cancer patients treated with anti- idiotype monoclonal antibody vaccine that mimics the carcinoembryonic antigen Clinical and immune responses in melanoma patients immunized with an anti- idiotype antibody mimicking disialoganglioside GD2 Is IgG galactosylation the relevant factor for pregnancy- induced remission of rheumatoid arthritis? |
| cord-016960-xhzvp35g | The wolf in sheep's clothing: the role of interleukin-6 in immunity, inflammation and cancer Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production Microchimerism: incidental byproduct of pregnancy or active participant in human health? |
| cord-016960-xhzvp35g | Tocilizumab: therapy and safety management Swedish natalizumab( Tysabri) multiple sclerosis surveillance study Partial reduction of human FOXP31 CD4 T cells in vivo after CD25-directed recombinant immunotoxin administration Enhancement of cell- mediated immunity in melanoma patients immunized with murine anti- idiotypic monoclonal antibodies( MELIMMUNE) that mimic the high molecular weight proteoglycan antigen Fc receptors in immune thrombocytopenias: a target for immunomodulation? |
| cord-016960-xhzvp35g | VACTERL association? |
| cord-016960-xhzvp35g | blocking antibodies transmitted from mother to child Prenatal diagnosis of Huntington disease in maternal plasma: direct and indirect study Pregnancy outcomes in patients with systemic autoimmunity Understanding systemic lupus erythematosus physiopathology in the light of primary immunodeficiencies Tumor necrosis factor- a inhibition and VATER association: a causal relationship? |
| cord-016960-xhzvp35g | case report and literature review Lethal vasculitis of coronary arteries in a neonate and two infants: possible neonatal variant of the MLNS/ IPN complex? |
| cord-347298-7kqrl3rv | , why are such reactions not more common? |
| cord-347298-7kqrl3rv | LPS Flagellin/ Profilin ? |
| cord-347298-7kqrl3rv | Significant ROS include the superoxide anion( O 2-), hydrogen peroxide( H 2 O 2), the hydroxyl radical( HO?), nitric oxide( NO?), and the peroxynitrite anion( ONOO À). |
| cord-347298-7kqrl3rv | Significant ROS include the superoxide anion( O 2-), hydrogen peroxide( H 2 O 2), the hydroxyl radical( HO?), nitric oxide( NO?), and the peroxynitrite anion( ONOO À). |
| cord-347298-7kqrl3rv | The question then arises: if immune responses against exogenous and endogenous antigens are inhibited in the testis environment, does the testis display a reduced capacity to deal with infections and greater susceptibility to certain kinds of tumors? |
| cord-022888-dnsdg04n | /CRTAM on gd T cells? |
| cord-022888-dnsdg04n | As the results show, could there not be a direct relationship between the HLA system and the development of SA or TBC, or in contrast, was the first patient missdiagnosed of TBC being a good prognosis SA? |
| cord-022888-dnsdg04n | Could Carabin play a role of negative regulator of B cell function? |
| cord-022888-dnsdg04n | How is the IGSF4-CRTAM axis regulated in T cells? |
| cord-022888-dnsdg04n | a one- year prospective birth cohort study PC09/16 TO WHAT EXTENT T- SPOT.TB COULD BE USED IN THE DIAGNOSIS OF TUBERCULOSIS IN CHILDREN EXPOSED TO TB INFECTION? |
| cord-006230-xta38e7j | 2´-deoxy- cAMP in human cell lines: Another second messenger? |
| cord-006230-xta38e7j | > Ser Extra- adrenal glucocorticoid synthesis in the intestinal epithelium: more than a drop in the ocean? |
| cord-006230-xta38e7j | Converging of the classical mitochondria- related pathway in Parkinson and nuclear DNA- repair signaling? |
| cord-006230-xta38e7j | Detoxification by conjugation of glutathione? |
| cord-006230-xta38e7j | Is formaldehyde a good example for a"genotoxic carcinogen"with a threshold mode of action? |
| cord-006230-xta38e7j | The transcriptome analyses of human cells showed that additionally to the 30.000 protein coding sequences the human DNA codes for much more( 450.000?) |
| cord-006230-xta38e7j | possible link between diabetes and cancer? |
| cord-344204-qq2vqzc2 | An insight into the sex differences in COVID-19 patients: what are the possible causes? |
| cord-344204-qq2vqzc2 | High- glucose- induced nuclear factor κB activation in vascular smooth muscle cells COVID-19: a new virus, but a familiar receptor and cytokine release syndrome Acute kidney injury in patients hospitalized with COVID-19 Understanding the renin- angiotensin- aldosterone- SARS- CoV- axis: a comprehensive review COVID-19 as a STING disorder with delayed over- secretion of interferon- beta Thrombotic microangiopathy in a patient with COVID-19 COVID-19: what treatments are being investigated? |
| cord-344204-qq2vqzc2 | NF- kB signaling is the molecular culprit of inflammaging Tranmer GK Taming the cytokine storm: repurposing montelukast for the attenuation and prophylaxis of severe COVID-19 symptoms NF- κB in renal inflammation COVID-19: risk for cytokine targeting in chronic inflammatory diseases? |
| cord-344204-qq2vqzc2 | SARS- coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum Coronavirus infection( SARS- CoV-2) in obesity and diabetes comorbidities: is heat shock response determinant for the disease complications? |
| cord-344204-qq2vqzc2 | What is the role of supplementation with ascorbic acid, zinc, vitamin D, or N- acetylcysteine for prevention or treatment of COVID-19? |
| cord-344204-qq2vqzc2 | Why does COVID-19 disproportionately affect older people? |
| cord-344204-qq2vqzc2 | a clue from innate immunity Azithromycin for COVID-19: more than just an antimicrobial? |
| cord-020643-0yzkqykg | A controlled trial of dichloroacetate for treatment of lactic acidosis in adults Der Darm als immunologisches Organ Apheresis as therapy for patients with severe sepsis and multiorgan dysfunction syndrome Plasma exchange as rescue therapy in multiple organ failure ncluding acute renal failure Treatment strategies for acute myocardial infarction complicated by cardiogenic shock in a community hospital Enterale Immunonutrition: wann, für wen, welche Zukunftsperspektiven gibt es? |
| cord-020643-0yzkqykg | Bestandteil des Multiorganversagens in der Sepsis? |
| cord-020643-0yzkqykg | Dysfunktion seiner Patienten Beachtung schenken? |
| cord-020643-0yzkqykg | Endemie- Erfassung der Ostalbregion und Literaturübersicht Hemodynamic and metabolic effects of low- dose vasopressin infusions in vasodilatory septic shock Inhibition of 38 mitogen activated protein kinase: a novel strategy in sepsis? |
| cord-020643-0yzkqykg | One- year outcomes in survivors of the acute respiratory distress syndrome Does immunonutrition in patients with sepsis do more harm than good? |
| cord-020643-0yzkqykg | Patienten? |
| cord-020643-0yzkqykg | Should we emergently revascularize occluded coronaries for cardiogenic shock? |
| cord-020643-0yzkqykg | Should we emergently revascularize occluded coronaries for cardiogenic shock? |
| cord-020643-0yzkqykg | Sind diese in der Diagnostik nutzbar? |
| cord-020643-0yzkqykg | Ursachen oder Folgen? |
| cord-020643-0yzkqykg | an acute myocardial infarction Organ apoptosis in the septic patient: A potential therapeutic target? |
| cord-020643-0yzkqykg | ein Nierenversagen? |
| cord-020643-0yzkqykg | sind MODS- anfällig? |
| cord-020643-0yzkqykg | systemic infl ammatory response syndrome Cytokines, nitrite/ nitrate, soluble tumor factor receptors, and procalcitonin concentations: Comparison in patients with septic shock, cardiogenic shock, and bacterial pneumonia Coronary hemodynamics and myocardial metabolism in sepsis and septic shock Kristalloide versus Kolloide-A never ending story? |
| cord-015910-d9gxew91 | --how strong is the association? |
| cord-015910-d9gxew91 | A fundamental question is which precedes the other- the general increase in inflammation or the development of diseases with overt and covert inflammatory bases? |
| cord-015910-d9gxew91 | Are these phenomena an unfortunate side effect of maturity, or is there a common mechanism that determines the appearance of these diseases patterns in the elderly.'? |
| cord-015910-d9gxew91 | Could glutamine be exerting an anti- inflammatory influence via an effect on GSH that enhances immune function? |
| cord-015910-d9gxew91 | Do the general findings from this type of study also apply to modulation of low- grade chronic inflammation, such as has been observed in the elderly and obese? |
| cord-015910-d9gxew91 | Does N- acetyl cysteine inflkuence cytokine response during early human septic shock? |
| cord-015910-d9gxew91 | Free RadicalBiology andMedicine Do men and women follow different trajectories to reach extreme longevity? |
| cord-015910-d9gxew91 | Genetically determined? |
| cord-015910-d9gxew91 | Involvement of IkappaB- alpha stabilisation Are differences in interleukin 10 production associated with joint damage? |
| cord-015910-d9gxew91 | Is major histocompatibility complex polymorphism relevant to the control of human longevity? |
| cord-015910-d9gxew91 | Is there, therefore, a link between this phenomenon and increased levels of inflammation? |
| cord-015910-d9gxew91 | The roles of Nramp 1 and Tnfo~ genes in nitric oxide production and their effect on the growth of Salmonella typhimurium in macrophages from Nrampl congenic and tumor necrosis factor- alpha-/-mice Polymorphism of the human TNF- cz promoter-- random variation or functional diversity? |
| cord-015910-d9gxew91 | What mechanisms could result in this divergent effect? |
| cord-015910-d9gxew91 | Why does tissue GSH content have differing effects on immune cell populations depending on whether or not an inflammatory response is occurring? |
| cord-256838-8rzibpbl | A clue to Balkan endemic nephropathy? |
| cord-256838-8rzibpbl | Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids Is there an association between ephedra and heart failure? |
| cord-256838-8rzibpbl | Are these molecules specific for that specific activity of a TCM formula or herbs? |
| cord-256838-8rzibpbl | Could a specific ADR come from interactions between specific active molecules? |
| cord-256838-8rzibpbl | Could the gut microbiota reconcile the oral bioavailability conundrum of traditional herbs? |
| cord-256838-8rzibpbl | Could these activities be extrapolated into humans? |
| cord-256838-8rzibpbl | Could these inactive ingredients be omitted? |
| cord-256838-8rzibpbl | Could they reach a minimal serum level to exert that particular pharmacologic activity in humans? |
| cord-256838-8rzibpbl | Does publication bias exist so that undesired pharmacologic effects are not published? |
| cord-256838-8rzibpbl | Is it possible that a particular gene is prone to a specific ADR of a TCM formula or herbs? |
| cord-256838-8rzibpbl | Is it possible that herbs and TCM formulas can be effective in this low concentration of bioactive compounds? |
| cord-256838-8rzibpbl | Is it possible that interactions between active molecules, e.g., synergism, but not active molecules themselves, account for a specific activity? |
| cord-256838-8rzibpbl | Is it possible that little amount of bioactive molecules can cause interactions? |
| cord-256838-8rzibpbl | Is it possible that new active molecules are generated during preparation of the TCM formula? |
| cord-256838-8rzibpbl | Is it possible that the clinical effects of herbs and TCM formulas can be effective with such a small amount of bioactive compounds? |
| cord-256838-8rzibpbl | Is it possible that there might be unidentified active molecules that actually account for a particular pharmacologic activity? |
| cord-256838-8rzibpbl | Is there a specific gene or single nucleotide polymorphism( SNP) largely affecting the pharmacokinetic profile? |
| cord-256838-8rzibpbl | Positive or Negative Actors? |
| cord-022940-atbjwpo5 | , What is the role of Ministry of Health? |
| cord-022940-atbjwpo5 | Are antibiotics against which the strain is resistant inducing the changes in bacterial proteome? |
| cord-022940-atbjwpo5 | Can YKL-40 be an inflammatory biomarker in vitamin D deficiency? |
| cord-022940-atbjwpo5 | Hemolysis and test rejection: are we following a reliable process? |
| cord-022940-atbjwpo5 | His- flag tag as a fusion partner in insect expression systemgain or loss? |
| cord-022940-atbjwpo5 | How does different lead levels affect TSH, FT3, FT4, vitamin B12 and folate? |
| cord-022940-atbjwpo5 | How preeclampsia affects oxidant status and antiinflammatory potential of breast milk? |
| cord-022940-atbjwpo5 | Is this strain characterized by other differences on a proteome level? |
| cord-022940-atbjwpo5 | It was intended to shed light on some questions such as, what is the place and importance of IVD in Turkey? |
| cord-022940-atbjwpo5 | MRM transitions used were m/ z? 250/164 for 8-iso- PGF 2a and m/ z? |
| cord-022940-atbjwpo5 | MRM transitions used were m/ z? 250/164 for 8-iso- PGF 2a and m/ z? |
| cord-022940-atbjwpo5 | Medical and biological illustrations for life sciences education: Is'a picture worth a thousand words'in visualizing medicine and science? |
| cord-022940-atbjwpo5 | P-04.01.1- 006 Host- pathogen interactions: is there a relationship between TLR 4 polymorphisms and tuberculosis in a group of Turkish patients? |
| cord-022940-atbjwpo5 | P-05.01.1- 015 Does causes 1800 MHz magnetic field application KRAS and P53 mutations in colon?: |
| cord-022940-atbjwpo5 | P-09.04.4- 108 Is there any relation between 50 g oral glucose challenge test and serum total oxidant- antioxidant status in pregnant woman? |
| cord-022940-atbjwpo5 | What are the responsibilities of educational institutions? |
| cord-022940-atbjwpo5 | What is extra to learn from protein drying measurements? |
| cord-015394-uj7fe5y6 | : Do They Change during Pregnancy? |
| cord-015394-uj7fe5y6 | A Role for Intrahepatic GLUT1? |
| cord-015394-uj7fe5y6 | Androgens Influence Human Luteal Cells Function? |
| cord-015394-uj7fe5y6 | Are Contractions at 24- 32 weeks Gestation Less Painful Than Those at Full Term? |
| cord-015394-uj7fe5y6 | Could Confined Placental Mosaicism Account for Adverse Perinatal Outcomes in IVF Pregnancies? |
| cord-015394-uj7fe5y6 | Fact or Fiction? |
| cord-015394-uj7fe5y6 | Following Periconceptional Undernutrition or Twinning in Sheep? |
| cord-015394-uj7fe5y6 | In these experiments we sought to answer the question,'Does anandamide( AEA) work in the same manner as THC?' |
| cord-015394-uj7fe5y6 | Is There Evidence for Aromatase Activity in the Stroma of Postmenopausal Ovaries? |
| cord-015394-uj7fe5y6 | Is There a Role for Fatty Acids in the Pathogenesis of Pre- Eclampsia? |
| cord-015394-uj7fe5y6 | Is There a Seasonal Pattern in the Incidence of Post- Cesarean Endometritis? |
| cord-015394-uj7fe5y6 | Necessary? |
| cord-015394-uj7fe5y6 | Pregnancy Outcome? |
| cord-015394-uj7fe5y6 | Reason To Change Intrauterine Referral Practice in the Netherlands? |
| cord-015394-uj7fe5y6 | Term Preeclampsia: Any Risk for the Neonate? |
| cord-015394-uj7fe5y6 | and What Are the Roles Played by Peroxynitrite in Preeclamptic Women? |
| cord-005814-ak5pq312 | * p<0.05 CAN vs NaCI? |
| cord-005814-ak5pq312 | 2) Are whole body changes in VAPCO2 and AVpH associated with parallel changes in regional circulation? |
| cord-005814-ak5pq312 | : We inquired all the nurses of the Intensive Care Unit of an Regional Hospital by an semiestructurated questionary which included personal data: age, sex, contractual relation, professional experience.., and opinion data: do you think to inform relatives is a nurse task?. |
| cord-005814-ak5pq312 | A HEROE? |
| cord-005814-ak5pq312 | A PROGNOSTIC FACTOR? |
| cord-005814-ak5pq312 | After more than 2 years clinical experience two aspects were investigated: What effort is necessary to install and support a CIS, and what is the benefit for patients and personnel on the ICU? |
| cord-005814-ak5pq312 | Are circular circuits safe? |
| cord-005814-ak5pq312 | CO, MAP, CVP, PCWP, PaO?, and Pv~ remained unchan NO administration. |
| cord-005814-ak5pq312 | Case report: A 41 year old man developed typical skin manifestations of HSP following an episode of severe( biliary?) |
| cord-005814-ak5pq312 | GS score difference seems suggestive and can be that an abnormal cerebral activity( hipofisary hormones?) may play a crucial role on onset of ARF in these patients. |
| cord-005814-ak5pq312 | In 35 patients with cardiogenic shock due to ischemic heart disease( N=26), heart failure( N=7) and valvulopathy( N=2), hemod31aamic data including measures of intravascular pressures, cardiac output and mixed venous gases were collected at regular times intervals, at least 3 times a da?. |
| cord-005814-ak5pq312 | In all 13 patients with positive blood cultures the clinical course of S, infection was complicated:? |
| cord-005814-ak5pq312 | In case ot GER persistence at the pH- metry on? |
| cord-005814-ak5pq312 | In this stud?', wc recorded the gastrointestinal motility of critically ill patients with abundant(> 250 mL/24 hours) fasting gastric aspirates. |
| cord-005814-ak5pq312 | Is there any way to individualise the triple H therapy when it is necessary? |
| cord-005814-ak5pq312 | TA Buckle? |
| cord-005814-ak5pq312 | The absence of this mechanism( right heart impairement?) |
| cord-005814-ak5pq312 | Therefore, extreme attention should be paid to the maintenance of an adequate mean arterial blood pressure( above 90 mmHg?) |
| cord-005814-ak5pq312 | We were considered that a patient had Ventilator associated pneumonia( VAP) when the specimens of Bronchoalveolar Lavage( BAL) or Protected Specimen Brush( PSI?,), ebb'ned through the bronchoscope, had one or more microorganisms in concentrations greater than 105 and 103 cfu/ ml respectively. |
| cord-005814-ak5pq312 | Where are we?. |
| cord-005814-ak5pq312 | Which of the next informafions do you think is more important? |
| cord-005814-ak5pq312 | and AVpH also reflect the onset of tissue hypoxia during endotoxemia? |
| cord-005814-ak5pq312 | thrombolytic therapy or pulmonary embolectomy? |
| cord-015021-pol2qm74 | ( 3) Should future clinical trials be based on new classifications of illness such as MODS, SIRS, APACHE III, SAP II, MRM, etc., or should trials be dedicated to specific diseases-urinary tract infections, pneumonia, trauma patients, cardiac surgery and other specific problems, rather than generalized problems of sepsis, the sepsis syndrome and other classifications? |
| cord-015021-pol2qm74 | 3-Is the ACCP classification of sepsis useful at the bedside to select oatients? |
| cord-015021-pol2qm74 | Abnormally high skeletal muscle pO 2 in septic patients and its normalization during recovery: Evidence against tissue hypoxia but for impaired oxygen metabolism of skeletal muscle? |
| cord-015021-pol2qm74 | Administration of exogenous IFN? |
| cord-015021-pol2qm74 | And, finally, how can the participants be sure that the trial will be stopped at the right time, to ensure that no treatment is given to any patient that might be harmful? |
| cord-015021-pol2qm74 | Are all eligible patients being studied, and their results reported? |
| cord-015021-pol2qm74 | Are all the participants truly unbiased about the relative merits of the regimens being studied? |
| cord-015021-pol2qm74 | Before using the model for risk of death in septic patients, is it mandatory to validate it( by calibration, i.e. goodness of fit, and discrin'dnation, i.e., ROC curves) first on a data base using the same definition for sepsis as in the trial and secondly on the placebo group of the trial? |
| cord-015021-pol2qm74 | Can it achives a significant improvement in the septic course, organ dysfunction, and final outcome? |
| cord-015021-pol2qm74 | Conversely, administration of anti- IFN? |
| cord-015021-pol2qm74 | Correlatively the RNI inhibitor MMLA induces in vitro a decrease in the rate of bacterial killing, fxom 78% to 57%, in macrophages triggered with IFN-?+ LPS. |
| cord-015021-pol2qm74 | How can organ dysfunction and/or failure be defined? |
| cord-015021-pol2qm74 | How should we decide which of them should be brought to clinical trial? |
| cord-015021-pol2qm74 | If there is agreement that thin is an appropriate antibiotic protocol, should it not be used in all seriously ill septic patients in the hospital? |
| cord-015021-pol2qm74 | In contrast, GF109203X significantly reduced ICAM-1 expression induced by Interferon- y( IFN-?) |
| cord-015021-pol2qm74 | In fact, the IFN-? and IL-1 induced adhesion of PBMC to cytokine treated HUVEC could be downregulated by the PKC- inhibitor, whereas TNFc~-and LPS- mediated adhesion was not influenced. |
| cord-015021-pol2qm74 | In other words, should we now begin to have clinical trials on specific diseases with causes that are known and can be attacked? |
| cord-015021-pol2qm74 | Interferon-? |
| cord-015021-pol2qm74 | Is like being compared with like-are all the end points and the standards for measuring them clearly defined so that they can not be misunderstood? |
| cord-015021-pol2qm74 | Is there any role for antioxidative therapy in sepsis? |
| cord-015021-pol2qm74 | Is truly informed consent being sought that will satisfy not only the patient's right to choose what happens to him, but also the law of the land? |
| cord-015021-pol2qm74 | MIF secretion also was induced by TNFoc( 1 ng/ ml) and IFN? |
| cord-015021-pol2qm74 | MIF secretion is induced by LPS, TNFc~ and IFN?. |
| cord-015021-pol2qm74 | Macrophages of C57BL/10ScCr mice are incapable of producing interferon-~( IFN~) which we could show to be obligatory for the production of IFN? |
| cord-015021-pol2qm74 | On closer investigation the impaired IFN? |
| cord-015021-pol2qm74 | The IFN? |
| cord-015021-pol2qm74 | The absence of sensitization to LPS in Lps d C57BL/10ScCr mice was identified as being due to their inability to produce interferon-7( IFN?). |
| cord-015021-pol2qm74 | The clinical"take"rate o? cultured epithelial autografts( CEA) has been observed to Increase with transplantation to allodermls, but the reasons for the improved clinical performance have not yet been defined. |
| cord-015021-pol2qm74 | The inability to produce adequate amounts of IL-2, most likely attributable to alterations in the transmission of signals from the cell membrane to the nucleus, results in incomplete proliferative T- cell responses to antigenic stimuli, while a lack of? |
| cord-015021-pol2qm74 | There are reports of nentrophil dysfunction in inflammatory disorders of the skin( 2), Are there dysfunctions concerning the unspecific host defense in SIRS, as well? |
| cord-015021-pol2qm74 | This has not happened, however, and the question is"Why not"? |
| cord-015021-pol2qm74 | This might be due to a preexisting( genetic?) or more likely to an epiphenomenal receptor defect. |
| cord-015021-pol2qm74 | We have investigated the proinflaznmatory oytokine secretion patter~ by PMN in patients following major~hermal or tra~ matic injury and in volunteers fellowinq endotoxemia.? |
| cord-015021-pol2qm74 | What are the definitions? |
| cord-015021-pol2qm74 | What are the issues, then, in 1994, to be dealt with at this symposium and congress? |
| cord-015021-pol2qm74 | What are the mechanisms? |
| cord-015021-pol2qm74 | What is the aplpiieability of study results in typical clinical situations? |
| cord-015021-pol2qm74 | What is the availability of speciftc antibiotics at a participating hospital? |
| cord-015021-pol2qm74 | Will the patient's physicians agree to the protocol choice? |
| cord-015021-pol2qm74 | Will they be helpful in the study and esro of patients? |
| cord-015021-pol2qm74 | Will this contribute to better clinical trials, information basis and better research? |
| cord-015021-pol2qm74 | Will we benefit Oleo from a more precise classification and definition of a non- outjty, a hodgu- podge of human disorders which have charsmeristic.s and manifestations of tissue injury, inflammation and infactian? |
| cord-015021-pol2qm74 | and?-IFN and T- helper-2( Th2) acting principally in inducing antibody formation with a secretion of IL-4, IL-5, IL-10 and TNF-[3 has still to be established within the context of major trauma. |
| cord-015021-pol2qm74 | anti- IFN-?( p<0.05). |
| cord-015021-pol2qm74 | or is it better to use a specific model for each trial? |
| cord-015021-pol2qm74 | ~is s?. |