bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
zika virus	1317
zikv infection	620
study design	539
case studies	484
background case	481
design method	387
results finding	375
virus infection	372
vero cells	233
blood bank	188
viral rna	187
infected cells	177
red blood	175
whole blood	151
pregnant women	144
results findings	144
design methods	138
blood donors	135
west nile	121
blood center	120
natal rgn	120
dengue virus	118
zikv natal	118
nile virus	106
blood cells	103
natural products	102
immune response	102
blood products	100
zikv strains	99
public health	95
blood cell	94
zikv rna	94
red cell	93
blood group	87
retinoic acid	85
antiviral activity	85
performed using	85
spinal cord	83
mg dl	81
united states	80
flow cytometry	79
blood components	79
viral replication	79
room temperature	78
sexual transmission	77
rbc units	76
transfusion medicine	73
statistically significant	72
zikv replication	71
type i	71
virus replication	70
blood transfusion	69
mouse model	68
yellow fever	68
body weight	67
previously described	67
blood product	67
neutralizing antibodies	66
transfusion service	65
french polynesia	65
represented sequences	64
viral load	63
significantly higher	62
zikv ns	62
stem cell	61
neutralizing antibody	61
cell culture	61
viral infections	59
days post	59
nervous system	58
significant difference	58
thermo fisher	57
blood donor	57
amino acid	57
medical center	57
viral genome	56
ebola virus	56
blood donation	55
rhce ce	54
cord uid	54
transfusion reactions	54
antibody screen	54
doc id	54
viral infection	52
rgn srips	51
bone marrow	51
immune responses	51
respiratory syndrome	50
weight loss	50
innate immune	50
spectrum antiviral	50
host cell	50
risk factors	49
pediatr radiol	49
cell lines	49
fisher scientific	49
previously reported	48
platelet count	48
viral loads	47
pfu ml	47
chikungunya virus	47
sg assembly	47
central nervous	47
red cells	46
ag mice	46
center background	46
blood samples	46
time points	45
massive transfusion	45
clinical trials	44
endoplasmic reticulum	44
congenital zika	44
motor deficits	44
positive samples	44
pregnant mice	43
stem cells	43
health organization	43
peripheral blood	43
nucleic acid	43
blood donations	43
abo rh	43
zikv challenge	43
rna copies	43
influenza virus	43
testicular tissue	42
quality control	42
way anova	42
mr imaging	42
blood centers	42
analyzed using	42
antibody titers	41
infectious virus	41
japanese encephalitis	41
animal models	41
encephalitis virus	41
reverse transcription	41
zikv strain	41
plaque assay	41
nk cells	41
virus entry	40
three times	40
aedes aegypti	40
mg kg	40
pathogen reduction	40
mean age	40
cell death	40
ng ml	40
magnetic resonance	40
world health	40
clinically significant	40
vaccine development	39
viral proteins	39
pediatric patients	39
infectious diseases	39
host cells	39
er stress	39
viral diseases	38
blood loss	38
antibody response	38
infected mice	38
red cross	38
blood type	38
rbc transfusion	38
virus disease	38
zikv ediii	37
may also	37
significant differences	37
cell line	37
respiratory syncytial	37
virus outbreak	36
apheresis platelets	36
syncytial virus	36
blood services	36
year old	36
cdna clone	36
zikv infections	35
fever virus	35
puerto rico	35
fetal brain	35
syndrome coronavirus	35
adverse events	35
blood volume	35
blood supply	35
endothelial cells	35
treated cells	34
statistical analysis	34
well plates	34
patient care	34
significantly different	34
life cycle	33
monoclonal antibodies	33
sickle cell	33
zika syndrome	33
statistical significance	33
viral protein	33
within hours	33
host immune	33
i interferon	33
rna viruses	33
copies ml	32
retrospective study	32
infectious disease	32
cell viability	32
viral titers	32
virus infections	32
computed tomography	32
rna synthesis	32
white matter	31
vertical transmission	31
mutant virus	31
time pcr	31
western blotting	31
natural product	31
medical record	31
negative control	31
zikv proteins	30
patient blood	30
treated mice	30
south america	30
dnk cells	30
results suggest	30
results showed	29
protein expression	29
ic values	29
virus associated	29
independent experiments	29
transfusion vol	29
unique teaching	29
imaging findings	29
viral particles	29
teaching points	29
cd cells	29
transfusion reaction	29
one year	29
rgn replicon	29
zikv infected	29
herpes simplex	28
case report	28
acid signaling	28
tissue culture	28
cell types	28
total number	28
packaging cells	28
immune cells	28
systematic review	28
yap island	28
graphpad prism	28
cells infected	28
blood management	27
emerging infectious	27
case series	27
plasma exchange	27
transfusion services	27
two different	27
infectious clone	27
rna replication	27
ediii protein	27
one patient	27
well plate	27
ns protein	27
hemolytic transfusion	27
east respiratory	27
sequence repeats	27
case presentation	27
breast milk	27
middle east	27
rare consensus	27
viral entry	27
immune system	27
significantly lower	27
rhesus macaques	27
serum samples	26
igg antibodies	26
patient safety	26
aurintricarboxylic acid	26
time rt	26
pcr assay	26
blood banks	26
blood component	26
acute respiratory	26
bovine serum	26
virus titers	26
consensus sequence	26
fetal interface	26
health care	26
birth defects	26
envelope protein	26
antiviral agents	26
least one	25
zikv mr	25
differential diagnosis	25
american red	25
high titer	25
month period	25
significantly increased	25
authors declare	25
virus particles	25
antibody identification	25
simplex virus	25
zikv inoculation	25
cell disease	25
study period	25
virus type	25
patient samples	24
clinical trial	24
false positive	24
rgn strain	24
flow cytometric	24
lethal mutagenesis	24
positive results	24
measured using	24
years old	24
severe acute	24
serial dilutions	24
first trimester	24
human cytomegalovirus	24
two groups	24
real time	24
barre syndrome	24
resonance imaging	24
arboviral diseases	24
virus transmission	24
motor neurons	24
zikv activity	24
bact alert	24
progenitor cells	24
inhibitory activity	24
emergency department	24
monoclonal antibody	24
gene expression	23
zika viruses	23
three days	23
fetal mri	23
soft tissue	23
neutralizing activities	23
class i	23
adverse effects	23
clinical practice	23
previous studies	23
electronic medical	23
new york	23
significant reduction	23
enveloped viruses	23
immunodeficiency virus	23
aedes mosquitoes	23
inhibit zikv	23
platelet counts	23
time point	23
mouse models	23
rescued virus	23
creative commons	23
rna virus	23
urine samples	23
platelet concentrates	23
brazil zika	23
neural tube	22
serially diluted	22
virus zika	22
culture supernatants	22
high levels	22
transfusion practice	22
head trauma	22
dna vaccine	22
fruit bats	22
determine whether	22
dependent manner	22
human immunodeficiency	22
neural progenitors	22
molecular testing	22
increased risk	22
neutralizing activity	22
total rna	22
placental barrier	22
virus infects	22
male mice	22
cells using	22
time period	22
units transfused	22
neural progenitor	22
antiviral activities	22
stress granules	22
zikv genome	22
determined using	22
virus rna	21
host factors	21
infected patients	21
virus production	21
cord blood	21
standard deviation	21
university hospital	21
donor center	21
blood safety	21
important role	21
predictive value	21
intensive care	21
two independent	21
human placental	21
disease control	21
rna polymerase	21
evaluated using	21
virus pathogenesis	21
regional blood	21
mayo clinic	21
frozen plasma	21
test results	21
mice infected	21
zikv diagnostics	21
iu ml	20
per year	20
commercially available	20
inhibits zika	20
year period	20
federated states	20
kindly provided	20
neurological disorders	20
reference laboratory	20
transfusion protocol	20
salivary gland	20
forming units	20
parental virus	20
congenital infection	20
washed three	20
old female	20
information system	20
hemolytic anemia	20
adc values	20
zika fever	20
protein synthesis	20
significantly decreased	20
per month	20
ionizing radiation	20
mice treated	20
bacterial contamination	20
platelet products	20
virus ns	20
inventory management	20
prospective study	20
data showed	20
different time	20
present study	20
plasma samples	20
amniotic fluid	20
scd patients	20
post mortem	20
flaviviridae family	19
therapeutic plasma	19
lumbosacral spinal	19
body fluids	19
zikv outbreak	19
hematopoietic stem	19
apheresis platelet	19
cerebrospinal fluid	19
health emergency	19
recent studies	19
retrospective analysis	19
cd deficiency	19
canadian blood	19
control group	19
structural proteins	19
average number	19
blood collection	19
linear regression	19
cell cycle	19
restriction sites	19
vaccine candidates	19
also tested	19
plasma units	19
dengue viruses	19
zikv transmission	19
rhd gene	19
intrinsic disorder	19
neural stem	19
samples tested	19
asian lineage	19
inhibited zikv	19
supplementary document	19
cell cultures	19
reading frame	19
infectious clones	19
ct scan	19
log copies	19
ediii alone	19
zikv vaccine	19
congenital anomalies	19
trauma patients	19
physical examination	19
type ii	19
buffered saline	19
supplementary table	19
platelet inventory	19
animal model	19
deferral rates	19
rare donor	18
calculated using	18
aedes albopictus	18
endemic areas	18
severe disease	18
specific antibody	18
positive control	18
hong kong	18
crystal violet	18
four patients	18
national blood	18
logistic regression	18
infectious particles	18
pediatric population	18
lamp assay	18
zika vaccine	18
lymph nodes	18
first time	18
graphpad software	18
patients received	18
diagnostic tests	18
usutu virus	18
platelet units	18
volume reduction	18
iron deficiency	18
may provide	18
hospital transfusion	18
brain barrier	18
final concentration	18
signal intensity	18
african genotype	18
protein ns	18
rbc transfusions	18
cell membranes	18
retrospective review	18
also observed	18
interferon signaling	18
cells transfected	18
sertoli cells	18
symptom onset	18
antigen expression	18
shell disorder	18
fetal bovine	18
infects human	17
strain prvabc	17
age group	17
dtt treatment	17
risk factor	17
eu eea	17
medium containing	17
pediatric radiologists	17
vitro quality	17
hcmv infection	17
brain organoids	17
subunit vaccine	17
hospital background	17
imaging techniques	17
blood ordering	17
membrane fusion	17
fetal demise	17
widely used	17
different cell	17
genome sequence	17
gold standard	17
last years	17
previous study	17
rejuvenation solution	17
zikv isolates	17
ifitm proteins	17
congenital zikv	17
shelf life	17
amino acids	17
neurological complications	17
stranded rna	17
abdominal pain	17
rhd beadchip	17
life technologies	17
median age	17
monoclonal anti	17
egfp reporter	17
chest ct	17
goat anti	17
human brain	17
donor screening	17
treated rbcs	17
genome replication	17
regression analysis	17
coding regions	17
zikv particles	17
different concentrations	17
per well	17
days later	17
cellular stress	17
female donors	17
epithelial cells	17
polymerase chain	17
see table	17
western hemisphere	17
pathogen inactivation	17
cell monolayers	17
low levels	17
platelet transfusion	17
dsdna viruses	17
seven days	16
per patient	16
fresh frozen	16
emerging viral	16
hours post	16
transfected cells	16
blood system	16
brain endothelial	16
zika igg	16
chain reaction	16
washed twice	16
nk cell	16
clinical outcomes	16
cohort study	16
donor samples	16
nucleotide sequences	16
white blood	16
virus genome	16
growth medium	16
future studies	16
another study	16
patients undergoing	16
case reports	16
growth factor	16
even though	16
virus strains	16
jamaican fruit	16
antiviral effect	16
serologic testing	16
repeat testing	16
clinical symptoms	16
infectious cdna	16
significantly reduced	16
replication cycle	16
abusive head	16
ml kg	16
isothermal amplification	16
new automated	16
unfolded protein	16
leucocyte depleted	16
high resolution	16
coding region	16
laboratory testing	16
influenza vaccine	16
genomic dna	16
scale bar	16
patients receiving	16
blood service	16
cells per	16
culture media	16
whole body	16
tertiary care	16
fetal morbidity	16
contrast enhanced	16
data suggest	16
serological specificity	16
endemic regions	16
plaque reduction	16
electron microscopy	16
standard curve	16
manual tube	16
ns proteins	16
similar results	16
pcr products	16
vero cell	16
tube testing	16
secondary antibody	16
nonstructural protein	16
antibody screening	16
congenital cytomegalovirus	16
tcid ml	16
weighted imaging	15
fluorescence intensity	15
voluntary blood	15
study demonstrated	15
trophoblast cells	15
high prevalence	15
patients showed	15
cd cd	15
brain tissues	15
virus stocks	15
nonstructural proteins	15
inhibitory effects	15
reverse genetic	15
infection zika	15
congenital brain	15
negative blood	15
inhibits zikv	15
western pacific	15
diagnostic tool	15
reagent red	15
solid phase	15
false negative	15
cell transplantation	15
results show	15
recently developed	15
serum albumin	15
whether zikv	15
severe neurological	15
disease virus	15
additive solution	15
ferritin levels	15
acute phase	15
care unit	15
terumo bct	15
adverse reactions	15
gestational age	15
rbc unit	15
one hour	15
krrk basic	15
western blot	15
significant increase	15
fda approved	15
mosquito bites	15
antiviral drug	15
human serum	15
cellular immune	15
rhd diiia	15
cell lysates	15
molecular detection	15
antiglobulin test	15
uninfected cells	15
high risk	15
immunosuppressed mice	15
image quality	15
amotosalen uva	15
asian genotype	15
stored rbcs	15
rbcs stored	15
olfactory ensheathing	15
described previously	15
using anti	15
among different	15
basic residues	15
zikv may	15
long term	15
supernumerary centrin	15
fold increase	15
weighted images	15
viral envelope	15
imaging modality	15
quality improvement	15
centrin foci	15
detect zikv	15
commonly used	15
time course	14
emergency release	14
ct examinations	14
human skin	14
hcv rna	14
corpus callosum	14
neg rbc	14
er membrane	14
mediated endocytosis	14
cells well	14
radiation exposure	14
human neural	14
protein response	14
mediated isothermal	14
patient population	14
side effects	14
comparator assay	14
protective efficacy	14
zikv envelope	14
chloroquine treatment	14
brain tissue	14
pandemic influenza	14
virus detection	14
recent study	14
infected individuals	14
blood screening	14
ct scans	14
error bars	14
copyright holder	14
old male	14
direct antiglobulin	14
viral pathogens	14
flow cytometer	14
detection limit	14
zika forest	14
hemolytic disease	14
live attenuated	14
plaque forming	14
trauma center	14
blood systems	14
fresh medium	14
pathogen reduced	14
healthy volunteers	14
human pregnancy	14
tested using	14
zikv neonates	14
human infection	14
old girl	14
turnaround time	14
multiple comparison	14
spinal motor	14
renal function	14
pluripotent stem	14
likely due	14
clinical signs	14
febrile illness	14
developing fetus	14
zikv infectious	14
expression levels	14
treated zikv	14
rbc products	14
results indicate	14
three independent	14
dexamethasone immunosuppression	14
vector control	14
tissue tropism	14
antibody screens	14
tube method	14
cytomegalovirus infection	14
significant antibodies	14
donor population	14
small number	14
positive cells	14
sciatic nerve	14
urinary tract	14
cells may	14
human plasma	14
blood transfusions	14
pilot study	14
ms ms	14
antibody responses	14
two patients	14
virus particle	14
using two	14
hemoglobin levels	14
male donors	14
zikv ir	14
zika vrna	14
confocal microscopy	14
rhesus macaque	14
protein kinase	14
reduced viral	14
rare sequence	14
mice immunized	14
sexual contact	14
negative rbcs	14
iron metabolism	14
high frequency	14
risk assessment	14
transfusion testing	13
control study	13
borne transmission	13
storage lesion	13
mass spectrometry	13
genotyping results	13
alexa fluor	13
generation sequencing	13
aegypti mosquitoes	13
obtained using	13
plasma membranes	13
sperm count	13
single unit	13
antiviral efficacy	13
yap state	13
performed within	13
perinatal transmission	13
single adjuvant	13
transfused patients	13
like activity	13
emergency blood	13
clinical presentation	13
early stage	13
slightly lower	13
mr zikv	13
take home	13
commons license	13
informed consent	13
one unit	13
rhd genotyping	13
human strains	13
virus strain	13
transfusion transmitted	13
hla antibodies	13
clinical manifestations	13
mg cells	13
recent outbreak	13
congenital heart	13
donated blood	13
assessed using	13
irradiated blood	13
motor cortex	13
one month	13
human igg	13
zikv prm	13
several studies	13
health concern	13
dengue vaccine	13
three patients	13
culture supernatant	13
antiviral drugs	13
low ferritin	13
thermofisher scientific	13
ex vivo	13
diagnostic accuracy	13
mouse sera	13
san diego	13
also found	13
vaccine design	13
primary human	13
renal failure	13
confirmed positive	13
antibody titer	13
home points	13
statistical analyses	13
early diagnosis	13
denv serotypes	13
viral genomes	13
huh cells	13
new world	13
immune evasion	13
centrosome organization	13
genital tract	13
transplant recipients	13
standard tube	13
brain development	13
investigate whether	13
transmembrane protein	13
case study	13
one hundred	13
buffy coat	13
may lead	13
antiviral effects	13
escherichia coli	13
within days	13
results demonstrate	13
university school	13
inhibitory effect	13
mononuclear cells	13
international license	13
strains tested	13
literature review	13
antiviral agent	13
blood count	13
primary antibodies	13
rapid spread	12
sanger sequencing	12
innate immunity	12
developing fetuses	12
molecular diagnostic	12
indirect immunofluorescence	12
blocking solution	12
replacement fluid	12
sequence analysis	12
igg antibody	12
codon usage	12
contrast media	12
subunit vaccines	12
diagnostic test	12
imaging procedures	12
also reported	12
examination revealed	12
specific primers	12
mutation frequencies	12
rgn infectious	12
molecular weight	12
mpl adjuvants	12
congenital malformations	12
persistent infection	12
congenital disease	12
associated protein	12
third trimester	12
see supplementary	12
predicted phenotype	12
allowed us	12
suspected cases	12
thawed plasma	12
secondary antibodies	12
academic medical	12
small bowel	12
mammalian cells	12
first isolated	12
oxidative stress	12
primary antibody	12
made available	12
alloimmunized patients	12
family members	12
group system	12
infection induces	12
nat yield	12
age groups	12
treatment group	12
rhd weak	12
immature platelet	12
viral pandemics	12
high throughput	12
molecular mechanisms	12
relatively low	12
possible association	12
risks associated	12
specific mabs	12
accession number	12
two cases	12
growth kinetics	12
intracellular trafficking	12
cells treated	12
control mice	12
vps score	12
mpl adjuvant	12
rhd negative	12
lipase activity	12
infected mothers	12
ns gene	12
significant impact	12
mosquito species	12
hcmv infected	12
large number	12
rabies virus	12
reactive samples	12
cost savings	12
first case	12
days following	12
cytopathic effect	12
brain defects	12
cmv promoter	12
nucleoside analogues	12
much lower	12
donate blood	12
antigen negative	12
cells ml	12
hospital blood	12
based transfusion	12
higher levels	12
pregnancy outcomes	12
color doppler	12
old boy	12
per group	12
management system	12
blood supplier	12
clinical use	12
vast majority	12
seminiferous tubules	12
virus life	12
results indicated	12
signaling pathway	12
two years	12
global health	12
kir ds	12
one day	12
vaccine clinical	12
will also	12
approved drugs	12
zika infection	12
mini kit	12
pleural effusion	12
log ec	12
antibody levels	12
buffy coats	12
marrow edema	12
transfusion recipients	12
stress granule	12
reduced zikv	12
te cells	12
dmem containing	12
cell membrane	12
stress response	12
dengue fever	12
based blood	12
per unit	12
iron overload	12
study aimed	12
recipient cells	12
vascular malformations	12
associated microcephaly	11
abo typing	11
recombinant zikv	11
transfusion safety	11
central venous	11
semen samples	11
cell processor	11
nip rhd	11
parental mr	11
human cortical	11
iron depletion	11
ns protease	11
hbv dna	11
results demonstrated	11
blood pressure	11
reference standard	11
cause fetal	11
purified zikv	11
reduction neutralization	11
clinical data	11
calculated based	11
mice zika	11
clinical diagnosis	11
strain pan	11
cd cell	11
data show	11
automated bp	11
significantly associated	11
patient received	11
best practice	11
donor plasma	11
author funder	11
protective immunity	11
hod otii	11
single ventricle	11
hemorrhagic fever	11
plt count	11
neutralize zikv	11
post thaw	11
reverse genetics	11
brain abnormalities	11
regional office	11
may play	11
cell cycles	11
based approach	11
cell migration	11
inflammatory response	11
forward primer	11
screening test	11
cell units	11
split rate	11
immunocompetent mice	11
zikv compound	11
observed using	11
neuroglial cells	11
skull base	11
female mice	11
randomization models	11
blood specimens	11
phone calls	11
treated group	11
compatible blood	11
two days	11
ab plasma	11
critically ill	11
mg ml	11
chronic hepatitis	11
new england	11
randomized controlled	11
mean fluorescence	11
hela cells	11
linked immunosorbent	11
emerging viruses	11
also performed	11
fluorescent protein	11
early stages	11
protein folding	11
denv infection	11
study zika	11
plasma replacement	11
studies showed	11
cep gt	11
adverse pregnancy	11
fetal transmission	11
binding protein	11
samples collected	11
bars represent	11
genbank accession	11
dengue infection	11
surface antigen	11
health system	11
pcr system	11
hematology analyzer	11
mouse anti	11
cell interactions	11
host interactions	11
host ap	11
cd tregs	11
analysis revealed	11
umbilical cord	11
csp bj	11
may contribute	11
considered significant	11
exact test	11
cell lysate	11
rna levels	11
tested positive	11
negative results	11
past years	11
large volume	11
clinical outcome	11
early detection	11
hb deferral	11
study shows	11
borne encephalitis	11
also inhibits	11
medical records	11
patient outcomes	11
apheresis donors	11
granted medrxiv	11
serologic properties	11
human zikv	11
ensheathing cells	11
multiple myeloma	11
cxcr pd	11
peer review	11
human monoclonal	11
response rate	11
assay using	11
adverse outcomes	11
lysis buffer	11
patient harm	11
micronesia zika	11
three cases	11
data set	11
normal limits	11
five days	11
syndrome outbreak	11
also evaluated	11
randomly selected	11
rh typing	11
signaling dysregulation	11
tranexamic acid	11
second dose	11
wide range	11
random variants	11
within normal	11
different zikv	11
titer anti	11
technician related	11
phase clinical	11
global public	11
pet ct	11
human primates	11
laboratory data	11
analysis showed	11
platelet transfusions	11
juvenile idiopathic	11
rabbit anti	11
positive predictive	11
african americans	11
slightly higher	11
antigen typing	11
reproductive organs	11
may help	11
reverse primer	11
significantly improved	11
fold serial	11
flavivirus infection	11
automated alinity	11
intracellular viral	11
course study	11
dpg levels	11
brain malformations	11
may cause	11
gastrocnemius muscle	11
healthy children	10
borne viruses	10
also determined	10
ethics committee	10
borne virus	10
prism software	10
first line	10
cold pbs	10
virus targets	10
plaque size	10
forming assay	10
rna extraction	10
brazil zikv	10
brazilian zika	10
human antibody	10
interferon treatment	10
mr virus	10
immunofluorescence staining	10
false positives	10
hindlimb motor	10
weeks old	10
rbc storage	10
outbreak associated	10
donor program	10
id rhd	10
ill patients	10
deep learning	10
final diagnosis	10
study demonstrates	10
pondr vlxt	10
hla class	10
nucleotide sequence	10
axial disease	10
unfolded proteins	10
purified inactivated	10
rhesus monkeys	10
per animal	10
pathogenic mutations	10
microcephaly cases	10
green monkey	10
chart review	10
cell entry	10
posted march	10
donor unit	10
spectra optia	10
disease pathogenesis	10
acute infection	10
fold dilutions	10
human mabs	10
rhd xt	10
diagnostic imaging	10
cohort studies	10
duke university	10
positive antibody	10
cell proliferation	10
drug administration	10
monitored daily	10
two distinct	10
left ventricle	10
cortical neural	10
polyethylene glycol	10
cell surface	10
inclusion criteria	10
result verification	10
specificity zika	10
plasmid containing	10
product wastage	10
three zikv	10
platelet additive	10
serologic weak	10
liver transplantation	10
modification systems	10
infected vero	10
tissue factor	10
zais qds	10
virus vaccine	10
packed red	10
compared using	10
limited data	10
data points	10
transmitted zika	10
following zikv	10
chronically transfused	10
version posted	10
days prior	10
total volume	10
apheresis procedures	10
ttp patients	10
viral titer	10
pcr detection	10
fresenius kabi	10
based zikv	10
previously healthy	10
cause severe	10
day post	10
virucidal activity	10
er lumen	10
natural infection	10
analysed using	10
ap donors	10
infectious titer	10
studies will	10
copies per	10
influenza viruses	10
post collection	10
vascular anomalies	10
experimental models	10
away time	10
us blood	10
htlv i	10
blood banking	10
patient identification	10
clinical diagnostics	10
using graphpad	10
among blood	10
lower levels	10
idiopathic arthritis	10
rbc alloimmunization	10
histological analysis	10
samples obtained	10
blood groups	10
attenuated zikv	10
previously published	10
platelet recovery	10
immunohematology reference	10
many viruses	10
phylogenetic analysis	10
new process	10
ct angiography	10
age range	10
following day	10
genus flavivirus	10
single donor	10
mps iva	10
infectious agents	10
way valve	10
heart disease	10
patients requiring	10
testing using	10
therapeutic potential	10
medical students	10
respiratory tract	10
healthy donors	10
least two	10
sf cells	10
pfu cell	10
cd expression	10
bowel wall	10
reference laboratories	10
avian influenza	10
wbc count	10
contrast enhancement	10
acid sequence	10
titer results	10
five patients	10
vena cava	10
using flow	10
also showed	10
detected using	10
bac cdna	10
doppler us	10
african green	10
reading frames	10
mhc class	10
stored rbc	10
factors associated	10
zikv epidemic	10
abo bw	10
sample collection	10
peg iat	10
research institute	10
childbearing age	10
reported cases	10
cross blood	10
zkv testing	10
baby units	10
digital radiography	10
rna level	10
data management	10
gene sequencing	10
crossing vessels	10
using standard	10
dendritic cells	10
clinically relevant	10
human diseases	10
key role	10
tissue sections	10
rbc alloantibodies	10
specific antibodies	10
i interferons	10
master mix	10
standard deviations	10
molecular evolution	10
sybr green	10
investigated whether	10
medicine background	10
sciatic notch	10
translation initiation	10
african lineage	10
storage period	10
reverse transcriptase	10
london uk	10
early pregnancy	10
neutralization assay	10
cell tropism	10
dependent rna	10
commons attribution	10
complete protection	10
underrepresented sequences	10
zikv pathogenesis	10
crossmatch compatible	10
lipid metabolism	10
task force	10
positive er	10
rpe cells	10
com scientificreports	10
pacific region	10
nonhuman primate	10
delayed hemolytic	9
human antibodies	9
attachment activity	9
body mri	9
laboratories indicated	9
pediatric patient	9
clinical course	9
willebrand factor	9
pg ml	9
york blood	9
cause congenital	9
scoring system	9
systematic reviews	9
malignant lesions	9
chemical proteomics	9
us examination	9
animal care	9
viral persistence	9
mouse igg	9
zikv cdna	9
four days	9
plasma wastage	9
thrombocytopenic purpura	9
cerus corporation	9
retrospectively reviewed	9
infectious dose	9
three groups	9
dose zikv	9
first report	9
wall thickening	9
ct findings	9
immucor neo	9
trima accel	9
much higher	9
horseradish peroxidase	9
diffusion restriction	9
zikv isolate	9
viral particle	9
congenital pulmonary	9
autoimmune hemolytic	9
transfusion practices	9
developing brain	9
os cells	9
patients treated	9
additional information	9
page followed	9
clone anti	9
international concern	9
based assay	9
rhd variant	9
also demonstrated	9
different types	9
global threat	9
rhesus monkey	9
closed system	9
latin america	9
cells derived	9
rbc antigens	9
among men	9
ge healthcare	9
platelet adhesion	9
suckling mice	9
brazilian zikv	9
several viruses	9
protein mab	9
upper gi	9
generated using	9
will provide	9
safe blood	9
nat screening	9
routine quality	9
positive donations	9
lethal challenge	9
week period	9
rbc exchange	9
allogeneic blood	9
hla antibody	9
tested negative	9
copy number	9
spondweni virus	9
wide spectrum	9
volume processed	9
cells kg	9
human blood	9
post transfusion	9
genomic rna	9
reporter gene	9
bacterial culture	9
zikv asian	9
clinical syndromes	9
cell fate	9
better understanding	9
zikv full	9
effective treatment	9
forming unit	9
high titers	9
reproductive tract	9
sexually transmitted	9
virus isolation	9
abdominal trauma	9
ediii proteins	9
hla typing	9
pizv dose	9
sample size	9
growth curve	9
platelet components	9
virus vaccines	9
tubular matrix	9
number ku	9
rhce cehar	9
second sample	9
cmap amplitudes	9
positive dat	9
septic transfusion	9
african american	9
domain iii	9
von willebrand	9
crosslinked proteins	9
nuclear import	9
human coronavirus	9
closely related	9
zikv molecular	9
current status	9
comparison tests	9
interacting proteins	9
open access	9
inventory levels	9
viral dna	9
cell histiocytosis	9
compound control	9
radiation dose	9
ortho clinical	9
liquid plasma	9
different stages	9
study days	9
neutralizing monoclonal	9
literature search	9
broadly neutralizing	9
natural killer	9
previous reports	9
competing interests	9
microcephaly associated	9
units per	9
strong correlation	9
cell response	9
better understand	9
human neutralizing	9
flavivirus genus	9
per milliliter	9
induced pluripotent	9
institutional review	9
improve patient	9
motor neuron	9
mesenchymal stem	9
immunized mice	9
humoral response	9
neutralizing human	9
zikv sequences	9
plasma volume	9
human fetal	9
progeny yield	9
also identified	9
gt gt	9
brain structures	9
control measures	9
reticulum stress	9
serological tests	9
acute pancreatitis	9
kidney transplant	9
indirect antiglobulin	9
also used	9
within weeks	9
one week	9
wild type	9
vaccine platforms	9
advisory committee	9
cell collection	9
laboratory information	9
adult patients	9
i ii	9
optic nerve	9
mr plasmid	9
high sensitivity	9
per ml	9
inferior vena	9
three different	9
untreated control	9
evidence based	9
placental tissues	9
teg results	9
glial cells	9
coding sequences	9
total blood	9
infected animals	9
patients underwent	9
platelet collections	9
among patients	9
patients without	9
surgical treatment	9
tumor volume	9
high specificity	9
gene sequences	9
induce cellular	9
may affect	9
pe patients	9
virus growth	9
antibodies prevent	9
paediatric patients	9
dna fragments	9
binding site	9
multiple comparisons	9
phase red	9
diffusion weighted	9
zikv entry	9
surgical blood	9
next generation	9
er density	9
restriction enzyme	9
mdck cells	9
skin cells	9
broad range	9
emerging arbovirus	9
blood derived	9
factor viii	9
study also	9
failed runs	9
south pacific	9
blood order	9
clinic background	9
blood sample	9
vertebrate hosts	9
inhibit viral	9
viral membrane	9
examined whether	9
dna replication	9
highly conserved	9
paediatric radiology	9
limited number	9
observer agreement	9
quantitative pcr	9
healthy adults	9
ediii subunit	9
mean number	9
thrombin generation	8
normal saline	8
per week	8
respiratory symptoms	8
hla matched	8
viral disease	8
broad spectrum	8
hgb hct	8
university medical	8
emergency units	8
aedes spp	8
procedures performed	8
national reference	8
probably due	8
human cd	8
pak lx	8
incubation period	8
transforming growth	8
structural basis	8
emergency use	8
rbc samples	8
deficient mice	8
disease activity	8
iron supplementation	8
mp content	8
values obtained	8
recombinant virus	8
two zikv	8
culture medium	8
ns antigen	8
cobe spectra	8
monkey kidney	8
american health	8
computer program	8
transfected packaging	8
platelet yield	8
antibodies isolated	8
virus envelope	8
rhd alleles	8
decidual nk	8
genetic analysis	8
viruses zika	8
conducted using	8
may become	8
using rt	8
platelet usage	8
also known	8
observational study	8
matched platelets	8
quantified using	8
using different	8
seminiferous tubule	8
peripheral neuropathy	8
infected control	8
vaccine efficacy	8
prevent zikv	8
serological testing	8
neutralizing mabs	8
clinical samples	8
negative controls	8
way analysis	8
study performed	8
immunohistochemical staining	8
zikv group	8
important implications	8
molecular biology	8
pan american	8
specific hits	8
chemical probe	8
ag mouse	8
laboratory operations	8
oneg rbcs	8
pediatric oncology	8
north america	8
dna viruses	8
weakly positive	8
biliary atresia	8
pathogenic viruses	8
markedly reduced	8
virus stock	8
homooligonucleotide repeats	8
confer protection	8
congenital duodenal	8
data indicate	8
may result	8
three reading	8
strain mr	8
rare donors	8
pacific islands	8
epidemiological studies	8
rare case	8
rare cases	8
irradiated rbcs	8
wastage rates	8
gel card	8
plaque assays	8
services background	8
recent outbreaks	8
correlation coefficient	8
disordered regions	8
zoster virus	8
myc antibody	8
interventional radiology	8
primary infection	8
immediate spin	8
simulated transfusion	8
cases reported	8
bpn bottles	8
first identified	8
reduce zikv	8
dtt treated	8
fetal microcephaly	8
vector competence	8
viral life	8
typing results	8
different blood	8
borne flavivirus	8
also revealed	8
patients may	8
partial plasma	8
spectrum anti	8
clinical disease	8
without affecting	8
additional studies	8
grade tumours	8
represent mean	8
zikv exposure	8
dependent enhancement	8
immunosorbent assay	8
least three	8
usage bias	8
severe reaction	8
cells expressing	8
rheumatoid arthritis	8
level i	8
neutrophil infiltration	8
tm cells	8
complete blood	8
cytometric method	8
significant correlation	8
matched units	8
cmnc protocol	8
culture infectious	8
mab binding	8
significant decrease	8
cell antibodies	8
inoculated onto	8
laboratory results	8
old woman	8
affected areas	8
igm positive	8
infected male	8
assay showed	8
targeted mabs	8
control samples	8
dimethyl sulfoxide	8
pcr test	8
control groups	8
calcusyn computer	8
also associated	8
storage duration	8
triglyceride levels	8
brain mri	8
considered statistically	8
plt units	8
dna samples	8
acute zika	8
fever without	8
initial presentation	8
neutralization test	8
vital organs	8
activated protein	8
final product	8
brain edema	8
primary hits	8
different groups	8
disease severity	8
structural protein	8
thrombotic thrombocytopenic	8
dot represents	8
waste management	8
portal vein	8
mm tris	8
infectious viral	8
time donors	8
one study	8
affected countries	8
brazilian strain	8
platelet clearance	8
laboratory diagnosis	8
human viruses	8
virus causes	8
controlled trials	8
less likely	8
oneg patients	8
higher risk	8
high incidence	8
mr images	8
infected cell	8
automated solid	8
rgn srip	8
infected human	8
third party	8
critical role	8
alloimmunization rates	8
small numbers	8
family flaviviridae	8
pediatric radiologist	8
technologist time	8
group antigen	8
brain microvascular	8
analytical sensitivity	8
ortho vision	8
software version	8
culture results	8
automated gel	8
male reproductive	8
phase i	8
also detected	8
active inflammation	8
spleen stiffness	8
platelet refractoriness	8
pe group	8
transfusion related	8
emergently issued	8
different viruses	8
low titer	8
independent variables	8
loading control	8
scimitar syndrome	8
recent advances	8
radiographic findings	8
healthcare system	8
inhibitory concentration	8
clinical evaluation	8
endemic countries	8
capsid protein	8
genome sequencing	8
two weeks	8
virus challenge	8
potent neutralizing	8
rh phenotype	8
nine patients	8
light chain	8
relatively high	8
strains isolated	8
brain tumours	8
readily available	8
true positive	8
product utilization	8
low dose	8
microplate reader	8
total bilirubin	8
rh blood	8
weeks among	8
bl mice	8
current study	8
crystal structure	8
review board	8
single dose	8
implementation period	8
chikungunya fever	8
procedure cd	8
mutant rzikv	8
recognition sites	8
study showed	8
lamp primers	8
transcription factor	8
group antigens	8
blood utilization	8
protective effect	8
process improvement	8
prevent zika	8
blood cultures	8
high correlation	8
coding sequence	8
cytotoxic concentration	8
transfusion hemoglobin	8
antiviral functional	8
postnatal imaging	8
diagnostic performance	8
time since	8
clinical management	8
actin served	8
high volume	8
staphylococcus aureus	8
molecular tweezer	8
plate format	8
palindromic sequences	8
asymptomatic patients	8
orp values	8
two radiologists	8
tpe procedures	8
like receptor	8
confidence intervals	8
mouse brain	8
fatty acid	8
manufacturing methods	8
abo blood	8
contrast agents	8
zikv titers	8
luminex bead	8
fold change	8
transcription loop	8
calyceal dilation	8
mouth disease	8
single amino	8
plaque phenotype	8
persistently infected	8
following transfusion	8
zikv diagnostic	8
sequence alignment	8
semen parameters	8
general population	8
cell antigens	8
group ab	8
test whether	8
blood flow	8
coronary artery	8
prbc units	8
ha antibody	8
misfolded unfolded	8
ferritin testing	8
bone cyst	8
disease onset	8
upload time	8
well known	8
acute zikv	8
pediatric trauma	8
zikv vaccines	8
clinical assays	8
first months	8
plain radiograph	8
mutation frequency	8
per cell	8
data analysis	8
emergent situations	8
brain injury	8
biosafety level	8
represented sequence	8
standard operating	8
clinical care	8
assay performance	8
fluid signal	8
appointment booking	8
patients presenting	8
medical director	8
hematological parameters	8
flavivirus infections	8
tract infection	8
asian strain	8
give blood	8
cell adherence	8
findings suggest	8
child abuse	8
cultured cells	8
focal lesions	8
virus persistence	8
brain damage	8
aca treatment	8
open reading	8
done using	8
plasma membrane	8
recent zikv	8
vertically transmitted	8
immunodetection assay	8
fibrinogen levels	8
rational design	8
new class	7
rbc genotyping	7
individual donation	7
drug development	7
abundant common	7
lineage zika	7
less severe	7
cytometry analysis	7
cell concentrates	7
maximum surgical	7
diagnostic testing	7
controlled trial	7
zikv copies	7
urgent need	7
future state	7
inhibit zika	7
internal medicine	7
joint space	7
transmitted via	7
significantly reduces	7
technical staff	7
prevent transfusion	7
lung disease	7
isotype control	7
disorder differences	7
sg markers	7
gestational week	7
fetal disease	7
george chen	7
intravenous immunoglobulin	7
reagent management	7
log pfu	7
infection using	7
diagnostic approach	7
mild disease	7
assays perform	7
donor deferrals	7
fluorescence signal	7
zikv immunodetection	7
best practices	7
diabetes mellitus	7
lateral ventricles	7
serial dilution	7
cancer center	7
south china	7
current state	7
plate reader	7
cns involvement	7
bac clone	7
corresponding virus	7
remote blood	7
cell supernatants	7
factors involved	7
ct group	7
hepatocellular carcinoma	7
quantitative real	7
fatality rate	7
molecular tweezers	7
potential therapeutic	7
olfactory nerve	7
local transmission	7
emerging pathogens	7
four different	7
wt sequence	7
lung injury	7
iatrogenic blood	7
exclude concomitant	7
index donations	7
using gamma	7
seizure activity	7
matched controls	7
potential complications	7
electronic ordering	7
dmem supplemented	7
acid substitution	7
detection system	7
adamts activity	7
south american	7
functional residues	7
zikv infects	7
virus may	7
frontal cxr	7
assisted ba	7
mri images	7
binding kinase	7
clone plasmid	7
month old	7
venous return	7
zikv multiplication	7
abbott diagnostics	7
transmission cycle	7
abo discrepancy	7
placental damage	7
automatic appointment	7
mr urography	7
partial protection	7
clinical setting	7
igm igg	7
reduction technology	7
considered positive	7
mri findings	7
will require	7
igg titers	7
type plasmid	7
fetal autopsy	7
adult ag	7
increased blood	7
high level	7
genome copy	7
southeast asia	7
samples showed	7
rh confirmation	7
dna extracted	7
dara treatment	7
examination showed	7
taken together	7
fort collins	7
rh haplotypes	7
zikv cases	7
platelet aggregation	7
imaging modalities	7
total cell	7
infected mouse	7
outside africa	7
swab samples	7
cd yield	7
genetic variants	7
health background	7
ncam antibody	7
like illness	7
hydrodynamic radius	7
asian zikv	7
hemoglobin level	7
microvascular endothelial	7
copy numbers	7
placental cells	7
transfusion hgb	7
listeria monocytogenes	7
study population	7
new insights	7
statistically significantly	7
oxygen affinity	7
preliminary report	7
effective doses	7
collected using	7
supplementary material	7
binding affinity	7
traveller returning	7
viruses doi	7
human respiratory	7
group received	7
assessed whether	7
vps scores	7
liver transplant	7
negative predictive	7
stable patients	7
virion assembly	7
study evaluated	7
virus impairs	7
phase ii	7
immunofluorescent staining	7
iron stores	7
clinical information	7
mk cells	7
related complications	7
zimmer biomet	7
phylogenetic trees	7
ic value	7
apparent diffusion	7
bac approach	7
molecular determinants	7
synthetic dna	7
will need	7
specific cellular	7
diffusion coefficient	7
protein interaction	7
clinical development	7
hbv infection	7
pneumatic tube	7
marburg virus	7
coagulation parameters	7
placental blood	7
transfusion protocols	7
sequences identified	7
sgs assembly	7
bacterial artificial	7
hospital customers	7
kg day	7
antibodies targeting	7
dara interference	7
htlv ii	7
dna sequences	7
positive rbcs	7
apoptotic cell	7
per day	7
inhibiting zikv	7
mers coronavirus	7
ost complex	7
wbc ul	7
nonhuman primates	7
cell receptors	7
neonatal intensive	7
infection causes	7
gregg williams	7
parenchymal volume	7
primate model	7
emerging infections	7
living cells	7
neural cell	7
virus dna	7
increased walk	7
strand rna	7
concomitant infections	7
replication complex	7
continued pressures	7
tubular matrices	7
type iii	7
tested mabs	7
may still	7
among pregnant	7
diagnostic samples	7
birth weight	7
rank test	7
causes birth	7
vessel wall	7
three cell	7
bone age	7
different clr	7
emd millipore	7
zurich ch	7
cmap amplitude	7
blue arrows	7
related failed	7
transfusion transmission	7
young children	7
blood mononuclear	7
mers cov	7
platelet collection	7
included patients	7
new clinical	7
lethal infection	7
antiviral therapies	7
years ago	7
post infection	7
two samples	7
published literature	7
viral titres	7
random blood	7
antibody testing	7
represent standard	7
growth factors	7
lateral ridge	7
zikv human	7
arbovirus infection	7
laboratory findings	7
zikv env	7
prediction algorithm	7
medicine service	7
rna detection	7
transcription pcr	7
procleix zikv	7
host proteins	7
infected patient	7
arbovirus infections	7
clinical specimens	7
vaccine candidate	7
phylogenetic tree	7
months post	7
comparative analysis	7
human transmission	7
inhibit type	7
leydig cells	7
six patients	7
laboratory tests	7
mortem imaging	7
supplementary data	7
murine model	7
control cells	7
relatively small	7
patient demographics	7
remains unclear	7
recent epidemics	7
commodity waste	7
specific igg	7
extracellular vesicles	7
hospital based	7
organ transplant	7
tubing segments	7
higher sensitivity	7
control zikv	7
conventional mri	7
five years	7
cmv infection	7
dynamic contrast	7
studies suggest	7
high grade	7
slice ct	7
adamts deficiency	7
cdna clones	7
process steps	7
final volume	7
days using	7
pulmonary sequestration	7
human neurospheres	7
antiviral compound	7
also noted	7
may serve	7
meconium peritonitis	7
reactive antibodies	7
supplementary figures	7
mark paradowski	7
mycophenolic acid	7
emerging zika	7
cell transfusion	7
hour post	7
days two	7
published data	7
vitro transcription	7
human placenta	7
community hospitals	7
including zikv	7
serial passage	7
independent variable	7
brain swelling	7
continuous variables	7
enhanced automation	7
placental macrophages	7
epidemic arboviral	7
novel antiviral	7
placental transfer	7
five mice	7
transmission electron	7
sylvatic transmission	7
treatment stage	7
data collected	7
two additional	7
clerical errors	7
study sponsors	7
icu patients	7
wrist radiography	7
infection damages	7
concurrent epidemics	7
ray imaging	7
donation frequency	7
small volume	7
maternal immunization	7
identified natural	7
study group	7
gt mefs	7
result showed	7
blunt abdominal	7
rhce variants	7
imaging studies	7
congenital rubella	7
significant effect	7
cell responses	7
secure texting	7
study day	7
jane bryant	7
statistical software	7
transfusion guidelines	7
close proximity	7
rubella virus	7
george schlauder	7
ediii without	7
clr concentrations	7
day prior	7
human pathogens	7
increased expression	7
received ivig	7
bovine viral	7
molecular genotyping	7
epidemic areas	7
lung ultrasound	7
vaccinia virus	7
chikungunya viruses	7
mice vaccinated	7
cells zika	7
abnormal risk	7
unit transfusion	7
stress responses	7
basal ganglia	7
viral polymerase	7
also significantly	7
significant changes	7
also assessed	7
acid test	7
least cells	7
mild symptoms	7
mutagenic activity	7
human stat	7
clinical studies	7
ns rna	7
walk away	7
panel cells	7
medical history	7
denv ediii	7
may require	7
may represent	7
without compromising	7
skeletal age	7
dexamethasone withdrawal	7
pcr using	7
interferon receptor	7
septic patients	7
operations demand	7
null phenotype	7
maternal blood	7
cfu ml	7
fluorescence microscope	7
one rbc	7
ml penicillin	7
high inhibitor	7
paediatric radiologist	7
patient underwent	7
exchange transfusion	7
using routine	7
infants born	7
gfp reporter	7
lactate dehydrogenase	7
among women	7
rare blood	7
recombinant type	7
immune cell	7
arachidonic acid	7
mayaro virus	7
clinical significance	7
infected group	7
vascular access	7
immune globulin	7
transfused per	7
state fmri	7
zikv serology	7