trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram frequency
background case studies481
study design method387
of zika virus327
zika virus infection266
the presence of230
as well as204
the number of202
the use of158
study design methods138
of zikv infection130
a total of119
zikv natal rgn118
in this study115
due to the107
west nile virus106
zika virus in105
in order to105
to determine the99
based on the96
red blood cells94
was used to93
virus infection in92
the development of92
of this study91
of the zikv90
red blood cell81
in the presence81
one of the79
to evaluate the79
in vero cells78
infected with zikv78
this study was78
the blood bank77
at room temperature75
there was no74
the risk of74
in patients with72
in addition to71
of the viral71
zikv infection in70
were used to70
of the virus70
study was to69
the absence of67
the effect of67
the detection of66
cd t cells64
been shown to62
were infected with61
against zikv infection60
was determined by60
the role of59
according to the59
for h at58
the most common57
was performed using57
vero cells were56
to assess the55
compared to the55
the need for53
there was a53
is associated with52
vero e cells52
transmission of zika51
the majority of51
natal rgn srips51
cells were infected50
the patient was50
the cells were50
zikv infection and50
it has been50
the percentage of49
thermo fisher scientific49
the aim of49
in response to48
we found that48
against zika virus48
s pediatr radiol47
central nervous system47
was added to47
in the americas47
the united states46
in the brain46
center background case46
a and b46
detection of zika46
in the absence45
the diagnosis of45
for the detection45
in vitro and45
analysis of the44
the levels of44
used as a43
the zika virus43
as previously described43
has been reported43
there is a42
found to be42
in pregnant women42
of zikv in41
were treated with41
the level of41
have been reported41
c for h40
up to days40
the treatment of40
the case of40
the time of40
the zikv natal39
hepatitis c virus39
has been shown39
has not been38
in the blood38
vitro and in38
and in vivo38
to determine if38
at our institution38
before and after38
sexual transmission of38
in the case37
was used for37
at the time37
added to the37
in children with37
the ability to37
for zika virus37
resulted in a36
of the most36
respiratory syncytial virus36
the purpose of36
compared with the36
was observed in35
the importance of35
zika virus outbreak35
of zikv rna35
can be used35
associated with the35
in french polynesia35
respiratory syndrome coronavirus35
to be a35
zikv e protein35
virus in the35
zika virus and34
aim of this34
for min at34
the viral genome34
weak d type34
in the first34
world health organization34
was detected in34
virus infection and34
included in the34
infection during pregnancy33
the amount of33
with zika virus33
there were no33
in our study33
was performed to33
has also been33
such as the33
was found to33
congenital zika syndrome32
of the brain32
the impact of32
be used to32
prior to the32
of blood products32
antiviral activity of32
each of the32
when compared to32
was associated with32
shown to be32
of the patients31
were used for31
for up to31
to investigate the31
detected in the31
in cell culture31
the incidence of31
in the united31
to zikv infection31
well as the31
as part of31
the expression of30
of patients with30
zikv infection is30
an increase in30
the implementation of30
and in the30
cells were incubated30
the course of30
most of the30
the central nervous30
infection in the30
the effects of30
was performed on30
the lack of29
to have a29
showed that the29
natal rgn replicon29
observed in the29
the other hand29
in contrast to29
the combination of29
unique teaching points29
sensitivity and specificity29
an average of29
was performed in29
on the other29
all of the29
this study is29
could not be28
years of age28
in the study28
a history of28
associated with a28
development of a28
consistent with the28
for zikv infection28
have not been28
in terms of28
zika virus associated28
is the most28
cells were washed28
retinoic acid signaling28
been associated with28
protection against zikv28
use of the28
was used as28
japanese encephalitis virus28
the results of28
as shown in28
increase in the28
any of the28
the frequency of28
zikv infection of28
role in the28
were determined by27
the evaluation of27
was defined as27
hek t cells27
type i interferon27
were found to27
is important to27
because of the27
to reduce the27
samples were collected27
a combination of27
than that of27
east respiratory syndrome27
of the study27
were incubated with27
of zikv natal27
total number of27
study is to27
balb c mice27
with or without27
and incubated for26
were performed in26
virus associated with26
part of the26
that zikv infection26
detection of zikv26
obtained from the26
in the same26
cells were fixed26
data not shown26
presence of the26
the objective of26
used to determine26
have been shown26
middle east respiratory26
in combination with26
purpose of this26
a patient with26
results suggest that26
there is no26
in the viral26
are needed to26
of viral rna26
and zika virus25
as described above25
present in the25
been reported in25
with zikv and25
of the disease25
and stored at25
zika virus from25
identified in the25
of natural products25
were added to25
a mouse model25
was performed by25
the addition of25
herpes simplex virus25
a transfusion vol25
the prevalence of25
american red cross25
it is important25
to identify the25
the ability of25
a number of25
the viral rna25
mlakar et al25
seen in the25
as a result25
there are no25
the supernatant was24
influenza a virus24
for patients with24
type and screen24
sickle cell disease24
the mutant virus24
b and c24
it is possible24
magnetic resonance imaging24
in the cytoplasm24
zikv and denv24
analysis was performed24
of the blood24
alum and mpl24
involved in the24
were observed in24
were analyzed using24
those of the24
can also be24
implementation of the24
by plaque assay24
yellow fever virus24
some of the24
objective of this24
and incubated at24
was removed and24
zika virus replication24
for the treatment24
were compared to24
the formation of24
on yap island24
the brain and24
the fact that24
similar to the24
at least one24
approved by the23
to examine the23
changes in the23
during the first23
with zikv infection23
should be considered23
be able to23
cells in the23
that of the23
of these patients23
of red blood23
the samples were23
severe acute respiratory23
was to evaluate23
acute respiratory syndrome23
testing was performed23
correlate of protection23
more likely to23
be associated with23
a variety of23
an moi of23
used in this23
medical center background23
to analyze the23
may be a23
to compare the23
difference between the22
due to a22
the production of22
significant difference in22
brazil zika virus22
infected with the22
patient blood management22
were obtained from22
the cause of22
these results suggest22
zikv rna in22
in which the22
are associated with22
were able to22
the authors declare22
in the literature22
as compared to22
found in the22
human immunodeficiency virus22
the identification of22
the feasibility of22
the onset of22
cells were seeded22
of west nile22
used for the22
of the patient21
high levels of21
the potential to21
were collected and21
to be the21
this is the21
of pregnant women21
of the er21
based on a21
a review of21
for detection of21
located in the21
in the us21
by flow cytometry21
have shown that21
weight loss and21
zikv in the21
an important role21
the total number21
of blood components21
a case of21
to determine whether21
in comparison to21
the innate immune21
derived from the21
the rate of21
weak d types21
or absence of21
the possibility of21
cells infected with21
the potential for21
of the new21
the severity of21
the world health21
the efficacy of21
no significant differences21
is one of21
the study was21
effect on the21
the assembly of20
of dengue virus20
for use in20
of ap m20
increased risk of20
the emergence of20
may not be20
depending on the20
residues of ifitm20
the context of20
the blood center20
in the number20
the host immune20
have also been20
states of micronesia20
to those of20
were associated with20
the most frequent20
electronic medical record20
the type of20
the present study20
did not have20
was carried out20
federated states of20
associated with an20
for the development20
presence or absence20
were used as20
neutralizing antibody titers20
the virus was20
viral rna was20
understanding of the20
the transfusion service20
zika virus infects20
massive transfusion protocol20
statistically significant difference20
in the context20
of sexual transmission20
washed three times20
combination of alum20
is the first20
differences in the20
with the zikv20
a series of20
a h n19
associated with zika19
were incubated at19
use of a19
patients who received19
that can be19
serial dilutions of19
natal rgn strain19
in the past19
associated with increased19
infection and microcephaly19
outbreak on yap19
the concentration of19
was used in19
important role in19
can lead to19
suggesting that the19
of whole blood19
were performed using19
and it is19
evaluation of the19
be used for19
kindly provided by19
cells were cultured19
safe and effective19
and ns b19
review of the19
rare consensus sequence19
morbidity and mortality19
were identified in19
presence of a19
were analyzed by19
mice treated with19
associated with zikv19
the antiviral activity19
within hours of19
were tested for19
influenza a h19
reported in the19
were divided into19
the host cell19
used in the19
in the setting19
not associated with19
viral rna synthesis19
related to the19
of the mutant19
blood center background19
not significantly different19
the control of19
test was used19
infected cells were19
cd and cd19
school of medicine19
no significant difference19
was seen in19
was able to19
rio de janeiro19
the goal of19
treatment of zikv19
in a patient19
a reduction in19
there is an19
ns a protein19
the presence or19
the setting of19
were identified by19
performed using the18
compared to those18
a year old18
at risk of18
in the pediatric18
is a rare18
used in combination18
the most abundant18
regions of the18
we present a18
members of the18
was significantly higher18
at the maternal18
in a large18
cells transfected with18
in both the18
at different time18
pre and post18
results showed that18
higher than that18
the release of18
were performed with18
found that the18
therapeutic plasma exchange18
the pathogenesis of18
in this case18
the flaviviridae family18
by the presence18
isolated from a18
were included in18
on zika virus18
is required to18
room temperature for18
the extent of18
were used in18
was measured using18
the spread of18
for disease control18
in both groups18
fetal bovine serum18
as a control18
viral loads in18
rna was extracted18
a significant reduction18
be due to18
of the zika18
and a cells18
hematopoietic stem cell18
stored for days18
of blood donors18
onset of symptoms18
the endoplasmic reticulum18
of children with18
are presented as18
revealed that the18
zika virus ns18
of the cases18
and safety of18
virus zika virus18
suggested that the18
the end of18
transmission of zikv18
in of cases18
were analyzed for18
need to be18
months of age17
shown in table17
no effect on17
was designed to17
of zikv and17
majority of the17
we compared the17
be detected in17
a range of17
was obtained from17
of e protein17
up to of17
hospital background case17
alum with mpl17
are shown in17
of which were17
three times with17
of a new17
is needed to17
virus infection of17
the spinal cord17
studies are needed17
added to each17
zika virus pathogenesis17
in a dose17
by zika virus17
to the development17
zikv can be17
to zika virus17
the study period17
different time points17
on day and17
none of the17
viral rna in17
stages of the17
region of the17
berberine and emodin17
is based on17
the study of17
in the diagnosis17
the university of17
in vero e17
to study the17
determined to be17
innate immune response17
and incubated with17
of red cell17
is known to17
suggest that the17
in the future17
zika virus zika17
the performance of17
of vero cells17
canadian blood services17
body weight loss17
were fixed with17
consensus sequence repeats17
presented as mean17
the fetus and17
which may be17
in the plasma17
indicated that the17
it should be17
cells were then17
hepatitis b virus17
were performed on17
were seeded in17
with a high17
led to a17
was evaluated by17
were stored at17
did not show17
was evaluated using17
activity of the17
of cells with16
infection in human16
asian and african16
and the cells16
but not in16
for evaluation of16
and spinal cord16
in pregnant mice16
in the testes16
limit of detection16
chan et al16
ebola virus disease16
average number of16
was isolated from16
in vitro quality16
in hek t16
serve as a16
and all of16
in agreement with16
h at room16
samples were tested16
and may be16
disease control and16
been reported to16
with respect to16
the day of16
to test the16
when compared with16
the parental virus16
zika virus disease16
were collected at16
multiplicity of infection16
was performed with16
a statistically significant16
mice infected with16
safety and efficacy16
not appear to16
is possible that16
associated with microcephaly16
the sensitivity of16
these natural products16
known to be16
for more than16
is thought to16
was found in16
on the day16
abusive head trauma16
transfected with the16
control and prevention16
were detected in16
the distribution of16
a panel of16
a result of16
to the centrosome16
sera and tissues16
denv and zikv16
zikv infection was16
fresh frozen plasma16
the safety of16
were purchased from16
pregnant women and16
the management of16
congenital zikv infection16
the average number16
male and female16
to each well16
can be performed16
in the last16
of at least16
virus infects human16
for the presence16
and of the16
viruses in the16
infection in a16
supplementary table s16
represented sequences in16
of the flaviviridae16
significantly higher in16
immune response to16
a systematic review16
public health emergency16
were positive for16
the same time16
polymerase chain reaction16
the time to16
infection in pregnant16
for at least16
lower than that16
determined by plaque16
and characterization of16
was incubated with16
size of the16
of a novel16
was confirmed by16
the last years16
h n virus16
for treatment of16
from the same16
disease of the16
viral replication and16
likely to be16
of the viruses15
a group of15
with zikv mr15
end of the15
in of the15
was consistent with15
to confirm the15
virus infection during15
appear to be15
a and c15
with microcephaly in15
inhibits zika virus15
levels of zikv15
at the same15
of transfusion medicine15
jamaican fruit bats15
in the development15
this is a15
days after the15
as a potential15
rna copies in15
the first trimester15
insights into the15
virus outbreak on15
in the western15
cases of zikv15
vero and a15
and cells were15
at risk for15
of the human15
it is also15
can be found15
of the first15
neural progenitor cells15
for pregnant women15
we report a15
can be detected15
in a single15
data were analyzed15
mutation in the15
infectious cdna clone15
significant difference between15
between the two15
of infectious virus15
studies have shown15
after the onset15
could be used15
the virus in15
has the potential15
in the testis15
of the samples15
is consistent with15
performance of the15
should be noted15
hemolytic transfusion reactions15
sequences that are15
krrk basic residues15
of ebola virus15
the need to15
infection zika virus15
virus replication and15
a public health15
the age of15
significantly higher than15
was assessed by15
zikv has been15
appears to be15
remains to be15
of the four15
cd t cell15
difference in the15
number of units15
isolated from the15
the accumulation of15
been reported that15
cells were treated15
implementation of a15
the infectivity of15
a role in15
to understand the15
significant differences in15
were significantly higher15
and serological specificity15
was identified in15
be used as15
inoculum was removed15
were collected from15
authors declare no15
in the pacific15
and specificity of15
hepatitis e virus15
information on the15
the e protein15
and infected cells15
to inhibit zikv15
to the blood15
the effectiveness of15
with and without15
the generation of15
to describe the15
retrospective review of15
to the cells15
isolations and serological15
with pfu of15
male a mice15
in pediatric patients15
z at dpi15
emergence in the14
in south america14
but did not14
the efficiency of14
basic residues of14
a decrease in14
a natural product14
mouse model of14
of ifitm and14
shown in figure14
the quality of14
it is not14
indicate that the14
hemolytic disease of14
data suggest that14
were cultured in14
supernumerary centrin foci14
in a mouse14
the immune response14
we performed a14
of alum with14
than in the14
were washed with14
by western blotting14
from january to14
the copyright holder14
centers for disease14
mice with zikv14
the ns a14
of a zikv14
it was found14
are known to14
and urine samples14
hcmec d cells14
brain endothelial cells14
we hypothesized that14
between zikv infection14
sequence of the14
viral load in14
are expressed as14
study was performed14
from whole blood14
i interferon signaling14
and cd t14
in sera and14
t cells in14
needs to be14
ranging from to14
of the three14
to of the14
likely due to14
unfolded protein response14
mediated isothermal amplification14
lumbosacral spinal cord14
with zikv inoculation14
emerging infectious diseases14
may be useful14
diagnosis of zikv14
found to have14
o neg rbc14
of a single14
levels of the14
is essential for14
final concentration of14
the mechanism of14
of the total14
phosphorylation of eif14
of infected cells14
host immune response14
stem cell transplantation14
only a few14
half of the14
were stained with14
the most potent14
and viral rna14
of the same14
dengue and chikungunya14
testes and epididymides14
lump et al14
the alinity s14
the patient had14
the electronic medical14
were performed by14
determine if the14
in transfusion medicine14
study was conducted14
role of the14
the differential diagnosis14
was extracted from14
are the most14
has led to14
viral rna replication14
in the table14
sequences in the14
of the fetus14
for the evaluation14
calvet et al14
ranged from to14
day and day14
was evaluated on14
was referred to14
results indicate that14
virus in brazil14
min at room14
responsible for the14
small number of14
viral rna copies14
blood samples were14
identified by the13
africa and asia13
blood bank and13
had no effect13
all of them13
a retrospective analysis13
mice immunized with13
take home points13
retrospective analysis of13
similar to that13
were reported in13
in the cell13
a zika virus13
be used in13
in zika virus13
in all patients13
correlated with the13
intensive care unit13
the accuracy of13
m and c13
to detect zikv13
and did not13
inhibit zikv infection13
dengue virus type13
of the left13
with the exception13
were grown in13
as described previously13
zikv infection by13
goal of this13
infection of the13
it may be13
should also be13
of up to13
expression of the13
reduce the risk13
the c protein13
the western hemisphere13
the viral protein13
the entry of13
the proportion of13
may lead to13
to measure the13
and dengue virus13
clinically significant antibodies13
be noted that13
from the blood13
be found in13
and zk c13
in the current13
a single adjuvant13
the increase in13
in different cell13
african and asian13
in infected cells13
and zika viruses13
of yellow fever13
in children and13
the rescued virus13
vertical transmission of13
its emergence in13
incubated for h13
zikv infection has13
at an moi13
in the zikv13
the assessment of13
the timing of13
the degree of13
a cause of13
microcephaly in brazil13
are able to13
zika virus transmission13
was measured by13
was the most13
conflict of interest13
considered to be13
washed twice with13
supplemented with fbs13
zika virus during13
were transfected with13
statistical analysis was13
were incubated for13
was collected from13
the placental barrier13
positive and negative13
should be used13
defined as the13
with a single13
served as a13
assay was performed13
be considered in13
has been associated13
statistical significance was13
the process of13
was assessed using13
we did not13
used to assess13
washed with pbs13
a cohort of13
data are presented13
aim of the13
further studies are13
significant reduction of13
of retinoic acid13
university school of13
were washed three13
old a mice13
immunized with ediii13
is characterized by13
to the er13
zika virus rna13
with sickle cell13
shown in the13
the acute phase13
in accordance with13
the comparator assay13
the natural products13
and after the13
patients with a13
reduction in the13
was admitted to13
neural stem cells13
was found that13
seems to be13
after treatment with13
rbcs stored for13
change in the13
creative commons license13
nile virus infection13
the plates were13
no statistically significant13
of zikv to13
were similar to13
with ediii alone12
a case report12
innate immune responses12
brain and spinal12
lead to the12
were detected by12
in ag mice12
reduction of the12
cells were identified12
congenital zika virus12
cases of human12
academic medical center12
and hcmec d12
case of a12
we show that12
direct antiglobulin test12
followed by a12
the exception of12
the recent outbreak12
a v mutation12
of our study12
the surface of12
antiviral activity against12
resulting in a12
and then the12
to allow for12
vast majority of12
time to publication12
li et al12
a safe and12
denv and chikv12
from zikv infection12
of zikv replication12
a retrospective study12
prior to transfusion12
number of rare12
findings in the12
higher than the12
the change in12
was to assess12
could lead to12
leads to the12
the availability of12
in the host12
was added at12
was determined to12
the in vitro12
large number of12
reported to be12
virus infection zika12
to our knowledge12
the patient is12
was analyzed by12
the association between12
be useful to12
were found in12
infection has been12
was not detected12
inhibitory activity of12
and replaced with12
culture supernatants were12
and japanese encephalitis12
structure of zika12
detection of the12
distribution of the12
prm and e12
the krrk basic12
heavy and light12
results indicated that12
and chikungunya virus12
on vero cells12
of the right12
zikv is a12
cells treated with12
due to its12
the patient and12
of size m12
allowed us to12
appear to have12
proven to be12
assessment of the12
we evaluated the12
of the current12
that could be12
of the host12
which can be12
the zikv strains12
of the ns12
bmsc and amsc12
of harringtonine was12
relative to the12
was shown to12
be explained by12
activity against zikv12
in these patients12
in the region12
aedes aegypti mosquitoes12
impact on the12
of the natural12
its ability to12
blood group system12
hemolytic transfusion reaction12
as we previously12
the induction of12
of influenza a12
that there is12
for minutes at12
were exposed to12
donors in the12
ic values of12
blood donor center12
performed in the12
of defa b12
t cells and12
of the donors12
performed using a12
risk factors for12
and compared to12
c and d12
disorder in the12
risks associated with12
of these viruses12
two independent experiments12
was analyzed using12
the egfp reporter12
the patients with12
the testicular tissue12
with the same12
genotyping was performed12
ns b and12
for zikv rna12
but not the12
the activation of12
the results were12
with regard to12
known to cause12
testis and epididymis12
was determined using12
urine and saliva12
in which a12
we were able12
a retrospective review12
it can be12
which has been12
susceptible to zikv12
to days after12
with a history12
is involved in12
the first time12
and mpl adjuvants12
of hepatitis b12
in the coding12
in the developing12
in the early12
was sent to12
all samples were12
should not be12
as high as12
of infection in12
experiments were performed12
the introduction of11
time course study11
within normal limits11
in the s11
who has granted11
a significant difference11
neutralizing antibody response11
we believe that11
will be discussed11
a reduction of11
the mice were11
z and aj11
a negative control11
at a large11
error bars represent11
protective efficacy of11
display the preprint11
expressed as the11
and should be11
were not significantly11
were within normal11
followed by incubation11
study demonstrated that11
and other flaviviruses11
then incubated with11
over the past11
mechanism by which11
c and e11
the difference between11
patients in the11
cells were transfected11
of these natural11
in the testicular11
lead to a11
into host cells11
rt on day11
after the first11
the limit of11
of the flavivirus11
diagnosis of pneumonia11
led to the11
automated alinity s11
the range of11
bpa and bpn11
with weak d11
h n influenza11
the rest of11
immune response and11
c and m11
course of the11
calculated based on11
between zika virus11
zikv and other11
the author funder11
global public health11
microcephaly and guillain11
for h to11
no conflict of11
olfactory ensheathing cells11
microcephaly in the11
to the fetus11
in case of11
in the treatment11
into the cytoplasm11
in pag c11
was to determine11
positive predictive value11
significant impact on11
treated with the11
of dengue and11
a diagnosis of11
these results demonstrate11
this article is11
structure of the11
with the use11
of cases of11
and can be11
model of zika11
use of blood11
are in the11
efficacy of the11
association between zika11
to investigate whether11
or in the11
to establish the11
were evaluated for11
as described in11
of bone marrow11
and dengue viruses11
t cells to11
amniotic fluid of11
that the virus11
contribute to the11
according to a11
which is the11
was performed at11
as a cause11
number of patients11
serologic properties of11
inhibited zikv infection11
spinal motor neurons11
mice zika virus11
care and use11
a recent study11
in the supernatant11
a license to11
higher levels of11
function of the11
in vivo and11
it would be11
the coding regions11
been used to11
used to analyze11
for the diagnosis11
have been described11
was conducted to11
in the pre11
presence of zikv11
viral protein ns11
to that of11
mock and zikv11
has been observed11
was applied to11
blood and blood11
as a consequence11
mmol g hb11
study zika virus11
approximately of the11
the creative commons11
early stages of11
was not statistically11
that had been11
release of zikv11
and other neurological11
results of the11
performed in a11
both zikv and11
properties of zika11
thought to be11
in a cells11
prior to infection11
it has also11
of rare consensus11
were evaluated by11
that the patient11
the virus to11
the analysis of11
and has been11
at this time11
emergency of international11
to zikv e11
in the evaluation11
no evidence of11
micronesia zika virus11
is necessary to11
virus replication by11
mri of the11
low levels of11
with the parental11
the in vivo11
an in vitro11
wide range of11
may also be11
plates were washed11
in relation to11
may be associated11
genetic and serologic11
is the author11
the location of11
to detect the11
and serologic properties11
in body fluids11
effect of the11
bone marrow edema11
who presented with11
b and ns11
it is a11
were collected for11
license to display11
zikv ns b11
the pediatric population11
acid signaling dysregulation11
described in the11
all patients with11
and efficacy of11
the function of11
in brazil and11
has been used11
are present in11
new automated alinity11
to estimate the11
in the second11
significant increase in11
was reported in11
zikv ediii protein11
has been demonstrated11
has granted medrxiv11
the utility of11
health emergency of11
study aimed to11
in a child11
with an epidemic11
without an adjuvant11
granted medrxiv a11
zika virus strain11
after symptom onset11
and at the11
cells were lysed11
the amino acid11
possible association between11
medrxiv a license11
are based on11
position of the11
rna in the11
suggests that the11
the interaction of11
preprint in perpetuity11
to rbcs stored11
host ap m11
transmitted by aedes11
in neonates and11
see supplementary document11
the preprint in11
virus life cycle11
that has been11
to display the11
in the control11
also been reported11
with zikv at11
significantly associated with11
were also tested11
been implicated in11
this preprint this10
of the population10
length of stay10
to enhance the10
mice in the10
and drug administration10
and could be10
to be determined10
against zikv challenge10
our understanding of10
at the end10
assay for the10
we investigated whether10
whole blood and10
as the mean10
and days post10
was replaced with10
of zikv from10
was created to10
hazin et al10
in the post10
predicted to be10
over the course10
is essential to10
were monitored for10
a lack of10
infection in french10
demonstrate that the10
show that the10
for hr at10
more than times10
holder for this10
of blood transfusion10
using graphpad prism10
outbreak associated with10
number of zikv10
and public health10
a key role10
hindlimb motor deficits10
the western pacific10
based on this10
was evaluated in10
was to investigate10
of the parental10
did not affect10
serologic weak d10
of chikungunya virus10
a maximum of10
the genus flavivirus10
regional office for10
is present in10
weeks after the10
analysis of variance10
blood donors were10
blood loss and10
red cross blood10
outbreak of zikv10
for a total10
and used for10
has resulted in10
the packaging cells10
white blood cell10
the antibody response10
between january and10
have been proposed10
with fetal bovine10
for this preprint10
the rhd gene10
is difficult to10
lower in the10
of units of10
flavivirus e protein10
our data showed10
likely to have10
and the viral10
in the present10
expressed as mean10
as measured by10
the result of10
the past years10
of zikv was10
supernatants were collected10
a case study10
specificity of the10
between zikv and10
were challenged with10
we sought to10
followed by western10
the footpad with10
the visionv r10
belongs to the10
the bact alert10
preprint this version10
zikv replication in10
is likely to10
as in the10
sensitivity was evaluated10
were more likely10
from two independent10
packed red blood10
id rhd xt10
the results showed10
studies were performed10
is required for10
a large number10
version posted march10
creative commons attribution10
was no difference10
and used to10
we report the10
the transfusion medicine10
and treated with10
contributed to the10
juvenile idiopathic arthritis10
weak d phenotype10
rest of the10
of the mice10
the control group10
the patients were10
during the acute10
to the number10
the cytotoxicity of10
was done by10
zikv was first10
of the main10
in clinical trials10
in any of10
dengue virus infection10
and leads to10
virus titers were10
the natural product10
and for the10
to calculate the10
the differences between10
prevention and control10
report a case10
levels in the10
of the other10
the cytoplasm and10
a subset of10
the following day10
to increase the10
and use of10
were measured by10
in human skin10
for h and10
and evaluation of10
binding and entry10
were applied to10
is an important10
brazilian zika virus10
age of the10
samples were taken10
to the original10
associated with congenital10
were obtained with10
adverse pregnancy outcomes10
these results indicate10
and function of10
as long as10
were performed to10
of motor deficits10
to ensure that10
this version posted10
comparison of the10
surface of the10
the emergency department10
regional blood center10
referred to as10
evaluation of a10
our blood center10
the progression of10
of fetuses with10
that did not10
in the third10
results in the10
play an important10
microcephaly and other10
different concentrations of10
of zikv e10
fig a and10
cd cells ml10
identity of the10
were transfused with10
zika virus targets10
in the human10
vero cells and10
can be seen10
type i interferons10
level of the10
strain of zikv10
play a role10
with pbs and10
in the footpad10
virus in urine10
to be able10
for each of10
at h post10
serological specificity zika10
the diagnosis and10
in most cases10
be aware of10
zk b and10
to ensure the10
trimester of pregnancy10
epidemic in brazil10
a wide range10
was first isolated10
used to infect10
cobasv r zika10
supported by the10
inhibition of zikv10
be performed in10
units were transfused10
the beginning of10
the length of10
and the number10
not detected in10
was positive for10
referred to the10
the developing fetus10
blood donors with10
for the first10
specificity zika virus10
in the right10
entered into the10
medicine background case10
plaque forming units10
of the liver10
zikv infection during10
patients had a10
the discovery of10
countries and territories10
with an moi10
neurons in the10
was kindly provided10
of stress granules10
titers were determined10
we developed a10
of the mean10
in all cases10
by the blood10
leading to a10
may contribute to10
number of under10
have been developed10
the vast majority10
the weak d10
used to compare10
fluid of fetuses10
the lumbosacral spinal10
the viral replication10
data are expressed10
tested on the10
in the c10
acute phase of10
shown to have10
at the blood10
were prepared from10
of cd t10
molecular detection of10
a dose of10
of the number10
similar to those10
arboviral diseases in10
in some cases10
to have an10
patient with a10
the influence of10
of the asian10
group a plasma10
to pregnant women10
significantly different between10
that defa b10
human neural progenitor10
virus in a10
were determined using10
the decision to10
the antibody screen10
in the central10
syndrome outbreak associated10
with mpl adjuvant10
african green monkey10
to the virus10
cellular immune response10
ease of use10
factors associated with10
fixed with paraformaldehyde10
persistence in the10
demonstrated that the10
food and drug10
old female with10
belonging to the10
at least two10
no difference in10
and stained with10
and or mf10
of patients who10
in the left10
infection of human10
were presented as10
copyright holder for10
were euthanized at10
the second dose10
at c for10
platelet additive solution10
of hepatitis c10
was no significant10
zikv rna copies10
the viral envelope10
used to identify10
the blood and9
that resulted in9
for the blood9
antibody screen and9
was negative for9
and in vitro9
one or more9
on the use9
sequences of the9
mutant virus was9
resulted in an9
the first case9
data show that9
a more balanced9
we describe a9
along with the9
human skin cells9
the above data9
in conjunction with9
of international concern9
an increased risk9
authors declare that9
random variants of9
virus rna in9
state of the9
included in this9
to rule out9
tend to be9
for whole blood9
ns and ns9
the benefits of9
were tested with9
delayed hemolytic transfusion9
member of the9
hb deferral rates9
bacterial contamination of9
the neutralizing antibody9
and brain organoids9
from zika virus9
in rio de9
in the spinal9
further research is9
to the same9
in brazil in9
protein mab g9
was performed for9
rhd and rhce9
the two groups9
infectious virus particles9
of micronesia zika9
comparison tests were9
not in the9
of denv and9
a broad range9
in the male9
infection with zikv9
in the adult9
incubated at room9
human cortical neural9
is due to9
has been previously9
critically ill patients9
in zikv infected9
patient safety and9
of these compounds9
the size of9
the potential of9
a mice were9
during the outbreak9
spread of the9
strains of the9
for the study9
because of its9
zikv and yfv9
to induce cellular9
the outbreak in9
the cost of9
was treated with9
resulted in the9
activation of the9
that zikv can9
the emergency blood9
was observed for9
as opposed to9
twice with pbs9
chikungunya virus infection9
the sequence of9
of the assay9
samples obtained from9
blood donors and9
can result in9
the supernatant of9
to better understand9
inferior vena cava9
other enveloped viruses9
compared to a9
rbc units were9
blood system for9
pc in plasma9
x l and9
of less than9
a model of9
together with the9
blood donors in9
after days of9
and blocked with9
linked to the9
similar results were9
u os cells9
pregnant women with9
the survey was9
sg assembly in9
tests were applied9
a prospective study9
in supplementary table9
antiviral effect of9
host immune system9
we used a9
induce cellular stress9
three independent experiments9
ortho clinical diagnostics9
determine the optimal9
during the period9
septic transfusion reactions9
compared to controls9
emerging and re9
which results in9
cortical neural progenitors9
high titer anti9
the experiments were9
wang et al9
of the immune9
copies in the9
in the zika9
over the last9
with that of9
the testes and9
of infectious diseases9
york blood center9
could be a9
were compared with9
in our institution9
mouse model for9
in parallel with9
of rare sequence9
fetuses with microcephaly9
have been identified9
the possibility that9
with the presence9
of the antibody9
a high titer9
rapid spread of9
lower levels of9
significantly different from9
whole blood derived9
removed and the9
immunoassay for the9
immunosuppressed mice with9
indicated that they9
zika virus infections9
leading to the9
these results indicated9
outbreak in the9
aim was to9
in figure b9
e cells were9
as previously reported9
mean number of9
zika virus strains9
plaque reduction neutralization9
is a potent9
been previously reported9
directly from the9
and microcephaly in9
igm and igg9
we conducted a9
divided into two9
more than days9
ml of plasma9
have been associated9
development of the9
have to be9
patients who had9
was followed by9
safety of blood9
to cells infected9
added to vero9
applied to compare9
page followed by9
patients who were9
be related to9
little is known9
performance of a9
to review the9
to further confirm9
with the wild9
during the study9
different types of9
e protein expression9
suspected cases of9
which resulted in9
an inhibitor of9
at hpi with9
were fixed in9
performed on the9
from patients with9
of the rhd9
in this population9
zika virus was9
compared to other9
cep gt gt9
the time course9
clinic background case9
first report of9
b and zk9
were seen in9
have found that9
biology of zika9
that zikv ns9
the cmv promoter9
supplemented with fetal9
inhibitors of zika9
pfu of rzikv9
broad range of9
a and anti9
log copies ml9
were subjected to9
specificity and sensitivity9
a final concentration9
new york blood9
the sensitivity and9
in of patients9
natural products in9
and west nile9
be the most9
more than of9
e protein mab9
key role in9
to meet the9
in animal models9
was extracted and9
and c proteins9
vero cells with9
three days post9
was calculated by9
and added to9
been observed in9
times with pbs9
we aimed to9
and eif g9
infected with pfu9
and fetal demise9
based on our9
is able to9
characterization of the9
these results are9
performed to determine9
the specificity of9
shown in fig9
used to detect9
attenuates their growth9
the third trimester9
to be used9
are consistent with9
by standard tube9
identification of the9
at seven days9
this study are9
virus outbreak in9
intensity of the9
the evolution of9
from amniotic fluid9
and flow cytometry9
aware of the9
the virus and9
limited number of9
zikv strains tested9
of the remaining9
this study aimed9
a single unit9
used as an9
french polynesia in9
is used in9
been detected in9
in the database9
a is the9
dependent rna polymerase9
hbv and hcv9
virus from the9
rna in semen9
with cold pbs9
an effort to9
it is recommended9
values of the9
rgn srips in9
collected from the9
procedures were performed9
was added and9
was performed and9
cells were collected9
at days post9
and vaccine development9
von willebrand factor9
characterization of a9
for diagnosis of9
is a significant9
and treated at9
as an alternative9
in whole blood9
not yet been9
microcephaly associated with9
patients with scd9
results show that9
supernatant was removed9
different zikv strains9
zikv infection are9
the m protein9
the ratio of9
the duration of9
transferred to the9
of these donors9
the gold standard9
autoimmune hemolytic anemia9
was calculated using9
can be transmitted9
t cells with9
the fraction of9
and do not9
it is likely9
is important for9
were maintained in9
a cells were9
cdna clone of9
top of the9
was less than9
data was collected9
molecular evolution of9
the value of9
the viral load9
was collected and9
to donate blood9
there have been9
was compared to9
motor deficits in9
amino acid sequence9
proved to be9
when used in9
the immucor neo9
of human infection9
of zikv ns9
of the time9
to that end9
was supported by9
accession number ku9
induced by zikv9
would be a9
present a case9
of viral replication9
treated at hpi9
in one patient9
type i and9
of t cells9
infected and treated9
to identify and9
to note that9
for red blood9
correlation between the9
with microcephaly and9
addition to the9
to improve the9
with zikv or9
did not appear9
of viral infections9
from a patient9
ct and mri9
in the decidua9
data were presented9
public health concern9
infection as a9
in endemic regions9
cells were stained9
multiple comparison tests9
the date of9
as a model9
the ap m9
for s and8
be a useful8
shadrick et al8
by using a8
was propagated in8
performed by the8
with the control8
in mice zika8
as the sole8
chikungunya and zika8
is dependent on8
a period of8
as the number8
membranes were intact8
to the zikv8
in our laboratory8
by incubation with8
of protection in8
as a positive8
virus pathogenesis and8
and attenuates their8
viral titers were8
the d antigen8
entry into the8
fink et al8
strains of zikv8
after zikv infection8
at days p8
hcmec d cell8
services background case8
stranded rna virus8
the mutant rzikv8
of medicine background8
the safety and8
progenitors and attenuates8
may be more8
in the group8
to vero cells8
loads in the8
to verify the8
negative for the8
the design of8
antibody screen was8
american health organization8
of neutralizing antibodies8
data on the8
used as the8
available under a8
viral replication cycle8
the viral life8
the replication of8
lower than the8
a control for8
infections in the8
were washed twice8
the centers for8
response to zikv8
and more than8
such as guillain8
this should be8
color doppler us8
e c e8
caused by the8
proteins in the8
acute zikv infection8
and detection of8
the titer of8
the mechanisms of8
sequencing of zika8
many of the8
present in semen8
is a novel8
transmission of the8
transfusion reactions and8
in patients who8
look at the8
to be more8
was not significantly8
has recently been8
cells with zikv8
could be observed8
by the same8
in uganda in8
institutional review board8
for inhibitors of8
in these cells8
be seen in8
abnormalities and guillain8
is a major8
units in the8
all other tissues8
and whole blood8
the initiation of8
can serve as8
is used for8
was comparable to8
report of a8
estimated to be8
rare case of8
aim is to8
brain abnormalities and8
of protection against8
challenged with zikv8
serve as an8
who had a8
immunized with pbs8
at the level8
has been detected8
stage of zikv8
component of the8
the differences in8
previous studies have8
to address the8
animal models of8
mayo clinic background8
has the ability8
the loss of8
than those in8
other tissues were8
the group with8
and m proteins8
with a positive8
the new process8
of viral load8
ars for h8
the most important8
zikv with an8
use of this8
of microcephaly and8
as a negative8
the development and8
the interaction between8
we determined the8
did not meet8
treated with ribavirin8
the unfolded protein8
was significantly increased8
are not available8
it is made8
that in the8
those in the8
a report on8
and the other8
confirmed the presence8
to test whether8
the first months8
was first identified8
under a is8
all patients had8
at least three8
our study was8
a wide spectrum8
time pcr system8
on the same8
detection and sequencing8
of the manuscript8
by using the8
virus infection by8
fold serial dilutions8
the detection limit8
the basis for8
lazear et al8
mice with dexamethasone8
of viral infection8
zika and chikungunya8
a a v8
results were compared8
was removed from8
was higher than8
the rare consensus8
methods were used8
using the same8
in a small8
are included in8
results were obtained8
prevent zika virus8
infection during the8
summarized in table8
in a pregnant8
confirmed to be8
infection and its8
approved for use8
of influenza virus8
for use on8
with an average8
on the zikv8
room temperature and8
did not identify8
thrombotic thrombocytopenic purpura8
antibodies isolated from8
shows that the8
cases have been8
in the ediii8
with ic values8
during pregnancy in8
in experimental models8
with zikv with8
culture infectious dose8
in the mouse8
in hcmec d8
with a mean8
neural progenitors and8
these data suggest8
corresponding to the8
on the cell8
is responsible for8
the application of8
hla class i8
university medical center8
also associated with8
what has been8
not have a8
results from the8
of nucleic acid8
pan american health8
the most recent8
endoplasmic reticulum stress8
made available under8
measured using a8
with congenital zika8
three reading frames8
a consequence of8
reagent red cells8
tissue culture infectious8
as an important8
a global public8
western pacific region8
models were used8
from french polynesia8
males and females8
we investigated the8
is known about8
virus infection a8
hcv and hiv8
the virus is8
to validate the8
rna replication and8
system for platelets8
antibodies against zikv8
for zikv and8
and implementation of8
ediii subunit vaccine8
were carried out8
this may be8
of congenital zikv8
and the use8
plasma membranes were8
study shows that8
flow cytometric method8
zikv infection at8
for in vitro8
we analyzed the8
genbank accession number8
was observed between8
carried out in8
c bl mice8
been proposed as8
the selection of8
of in vitro8
in pbs for8
in a timely8
isolated from wbcs8
using the following8
of childbearing age8
a zikv vaccine8
the genome of8
borne transmission of8
cells were used8
transforming growth factor8
standard of care8
during zikv infection8
the relationship between8
is recommended that8
of the molecular8
infection in pregnancy8
were monitored daily8
rare sequence repeats8
day or day8
analysis revealed that8
and the blood8
demonstrated that zikv8