bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
cystic fibrosis	450
results suggest	396
research funds	268
epithelial cells	253
present study	223
nervous system	216
gene expression	210
spinal cord	199
cell lines	186
graduate school	176
fluorescent protein	168
results indicate	159
plasma membrane	156
cell line	154
infected cells	152
central nervous	145
glial cells	139
cell surface	134
lung function	130
important role	127
wild type	122
lung disease	121
stem cells	120
mg kg	116
data suggest	113
cell death	113
transgenic mice	109
angelica tenuissima	107
pseudomonas aeruginosa	104
tenuissima nakai	104
kenyon cells	104
airway epithelial	103
progenitor cells	103
amino acid	100
green fluorescent	99
neuronal activity	96
type i	94
cell types	94
western blot	90
virus infection	89
microglial cells	88
molecular mechanisms	88
protein expression	88
viral replication	87
hela cells	87
results show	87
positive cells	86
innate immune	84
neural stem	83
mouse model	83
expression levels	82
accessory calyx	81
oxidative stress	80
cells expressing	80
cerebral cortex	79
taken together	79
determine whether	78
ko mice	77
knockout mice	76
previous studies	75
virus replication	75
ca i	74
national institute	74
gfp expression	73
significantly increased	72
findings suggest	72
immune response	71
confocal microscopy	71
significantly reduced	71
flow cytometry	71
stem cell	70
mean age	70
hippocampal neurons	70
molecular dynamics	70
performed using	69
significant increase	69
cell culture	68
cl pro	68
respiratory syndrome	68
inflammatory response	68
dorsal accessory	68
recent studies	67
transcription factor	67
rna viruses	67
schwann cells	66
synaptic transmission	66
gene therapy	66
fusion protein	66
synaptic plasticity	65
purkinje cells	65
prefrontal cortex	64
pulmonary function	64
time points	64
previously reported	64
mrna expression	64
visual cortex	64
endoplasmic reticulum	63
growth factor	63
cut sites	63
brain science	63
reporter gene	63
binding protein	63
inflammatory monocytes	62
membrane proteins	62
living cells	62
protein kinase	62
gene transfer	61
electron microscopy	61
amino acids	61
chikungunya virus	61
black flying	60
may contribute	60
brain regions	59
flying fox	59
fluorescence microscopy	58
bp kenyon	58
also found	57
chadox mers	57
dependent manner	57
cell proliferation	57
cell imaging	56
significant difference	56
multiple sclerosis	55
bronchial epithelial	55
fluorescent proteins	55
brain injury	54
rat brain	54
cortical neurons	54
cleavage sites	54
united kingdom	54
mechanisms underlying	54
single molecule	53
ng cells	53
previously described	53
pyramidal neurons	52
membrane protein	52
treated cells	52
days post	52
significantly decreased	52
protein synthesis	52
results demonstrate	51
nmda receptor	51
pulmonary exacerbation	51
mammalian cells	51
analysis revealed	51
ng ml	51
viral rna	51
cell type	51
research institute	51
membrane potential	51
hippocampal slices	50
protein levels	50
white matter	50
lipid membranes	50
two different	50
osaka univ	50
expressing cells	49
nutritional status	49
fluorescence intensity	49
airway epithelia	49
immune responses	49
significantly higher	49
microglial activation	49
cleavage site	49
syncytial virus	49
chikv ls	49
respiratory syncytial	49
neurodegenerative diseases	48
previously shown	48
rna interference	48
vero cells	48
significant differences	48
ca region	48
viral infection	47
dentate gyrus	47
university graduate	47
receptor antagonist	47
cell adhesion	47
fatty acids	46
body weight	46
human cells	46
kyoto university	46
results showed	46
room temperature	46
also observed	46
pulmonary exacerbations	46
deficient mice	46
may play	45
data show	45
blot analysis	45
syndrome coronavirus	45
binding sites	45
light scattering	45
mutant mice	45
projection neurons	45
human airway	44
mrna levels	44
transcription factors	44
live cell	44
fev predicted	44
airway surface	44
epithelial cell	44
reactive astrocytes	44
poorly understood	44
cell membrane	44
model system	43
cell cycle	43
binding site	43
mice showed	43
neuropathic pain	43
atomic force	43
time course	43
olfactory bulb	43
acute respiratory	42
situ hybridization	42
cftr expression	42
viral proteins	42
pyramidal cells	42
cut site	42
doc id	41
university school	41
western blotting	41
cftr gene	41
cord uid	41
cell viability	41
antiviral activity	41
channel activity	41
activated microglia	41
signaling pathway	41
real time	41
mg ml	41
fibrosis foundation	40
science institute	40
nmda receptors	40
gnrh neurons	40
animal model	40
severe acute	40
terminal pro	40
clinical trials	40
fidelity tc	39
precursor cells	39
key role	39
culture medium	39
granule cells	39
data indicate	39
cell migration	39
lipid bilayers	39
molecular mechanism	39
control group	39
medical university	39
host cell	39
apical membrane	39
nerve injury	38
first time	38
inflammatory cytokines	38
mouse brain	38
mass spectrometry	38
mushroom body	38
terminal processing	38
signaling pathways	38
transfected cells	38
two types	38
extracellular matrix	38
measured using	38
bovine serum	38
respiratory tract	38
cell biology	38
wt mice	38
preliminary results	38
osaka university	37
research center	37
fatty acid	37
immune cells	37
force microscopy	37
human bronchial	37
gene delivery	37
inhibitory effect	37
patch clamp	37
results indicated	37
substantia nigra	37
chloride channel	36
widely used	36
transmembrane conductance	36
terminal domain	36
airway epithelium	36
ex vivo	36
significantly lower	36
well plates	36
stranded rna	36
significantly different	36
well known	36
time pcr	36
mean fev	36
cftr protein	36
conductance regulator	35
rat hippocampal	35
will discuss	35
transgenic lines	35
significant decrease	35
analysis showed	35
neuronal cell	35
fox cells	35
brain barrier	35
heat shock	35
structural proteins	35
target cells	35
energy transfer	35
conformational changes	35
brain function	35
animal models	35
rna polymerase	35
adult patients	35
high levels	35
two groups	34
commonly used	34
gfp gene	34
united states	34
neurite outgrowth	34
cells transfected	34
intracellular ca	34
herpes simplex	34
target genes	34
antiviral activities	34
dopaminergic neurons	34
circuit current	34
lipid bilayer	34
cells using	34
examined whether	34
type mice	33
lateral protocerebrum	33
medical school	33
dynamics simulations	33
kyoto univ	33
sox cut	33
crucial role	33
previous study	33
large number	33
cell cultures	33
expression level	33
null mice	33
medical center	33
whole cell	33
motor neurons	33
cx cr	33
cell membranes	33
mm nacl	32
neuronal death	32
fibrosis transmembrane	32
motor performance	32
wide range	32
lentiviral vectors	32
mouse models	32
hippocampal ca	32
glial cell	32
side effects	32
cftr function	32
growth cone	32
simplex virus	32
ms patients	32
results obtained	32
tohoku univ	32
important roles	32
dorsal root	32
fusion proteins	32
protein interactions	32
mediated gene	31
cftr activity	31
endothelial cells	31
described previously	31
cells infected	31
may also	31
cord injury	31
action potentials	31
surface expression	31
autophagic flux	31
laser scanning	31
crystal structure	31
transgenic mouse	31
term potentiation	31
better understanding	31
free energy	31
molecular biology	31
surface liquid	31
glutamate receptors	31
immunodeficiency virus	31
control mice	31
suppressor activity	31
influenza virus	30
morphological changes	30
tokyo metropolitan	30
tg mice	30
treated mice	30
investigate whether	30
ion transport	30
gel electrophoresis	30
protein tag	30
may provide	30
orf gene	30
opc differentiation	30
least one	30
investigated whether	30
disease severity	30
pc cells	30
i will	30
middle east	30
ng glia	30
also known	30
pulmonary disease	30
tohoku university	30
lipid droplets	30
i sc	30
pg ml	30
like protease	30
different types	29
gabaergic neurons	29
pcg proteins	29
muc ac	29
expression pattern	29
drug delivery	29
highly expressed	29
study period	29
immune system	29
remains unclear	29
better understand	29
neural activity	29
cells showed	29
neutralizing antibodies	29
rna recombination	29
asl volume	29
vaccinia virus	29
fold increase	29
rna binding	29
long term	29
significant changes	29
results suggested	29
protein complex	29
optic nerve	29
allowed us	28
riken brain	28
mucociliary clearance	28
ca pyramidal	28
reverse genetics	28
culture system	28
neurotrophic factor	28
results provide	28
human brain	28
negatively charged	28
glutamate transporter	28
medium containing	28
cell bodies	28
two distinct	28
expression patterns	28
basal ganglia	28
independent experiments	28
transgene expression	28
critical role	28
nl min	28
microglia activation	28
total rna	28
fisher scientific	28
nagoya university	28
microarray analysis	27
glutamate receptor	27
sox cleavage	27
apical surface	27
functional role	27
gfp reporter	27
innate immunity	27
binding domain	27
total number	27
dendritic spines	27
viral protein	27
ion channels	27
hypertonic saline	27
visual information	27
type cftr	27
rnai suppressor	27
neuronal differentiation	27
ciliated cells	27
gfp fusion	27
atp release	27
recently reported	27
confocal laser	27
positive control	27
ligand binding	27
first step	27
thermo fisher	27
sensory neurons	27
auditory cortex	27
nitric oxide	27
signal transduction	27
cells compared	26
reactive oxygen	26
chapel hill	26
vesicular stomatitis	26
experimental data	26
magnetic resonance	26
corpus callosum	26
gfp substrate	26
pcr products	26
inflammatory responses	26
adult brain	26
gfp bac	26
intracellular calcium	26
stomatitis virus	26
infected mice	26
fluorescence spectroscopy	26
different cell	26
confocal microscope	26
studies will	26
post infection	26
disease virus	26
control cells	26
findings indicate	26
receptive field	26
antibiotic treatment	26
rsv infection	26
ablv infection	26
coding region	26
ms lesions	26
ampa receptors	26
live cells	26
cells treated	26
healthy controls	26
mm tris	25
gap junction	25
wistar rats	25
locomotor activity	25
single cell	25
primary cultures	25
information processing	25
viral genome	25
secondary structure	25
purkinje cell	25
growth factors	25
brain tissue	25
fluorescence lifetime	25
iv antibiotics	25
lentiviral vector	25
molecular weight	25
airway inflammation	25
correlation spectroscopy	25
adult mice	25
i ifn	25
spike protein	25
structural changes	25
class i	25
brain development	25
expression vector	25
antibiotic therapy	25
life cycle	25
glutamate transporters	25
cellular processes	25
postnatal day	25
rna replication	25
induced cell	25
test whether	25
life science	24
gfp protein	24
life sciences	24
quality control	24
sweat chloride	24
data demonstrate	24
sputum samples	24
physiological conditions	24
may lead	24
tissue culture	24
neural network	24
type iii	24
strand rna	24
porcine epidemic	24
type ii	24
mechanism underlying	24
genomic dna	24
bone marrow	24
binding proteins	24
molecular basis	24
expression vectors	24
transiently transfected	24
small molecule	24
image series	24
well understood	24
brain slices	24
fibrosis patients	24
amyloid fibrils	24
dendritic cells	24
negative control	24
i interferon	24
oxygen species	24
circular dichroism	24
functional recovery	24
neurons showed	24
phev infection	24
membrane fusion	23
protein folding	23
electron transfer	23
nucleic acid	23
stably expressing	23
red fluorescent	23
actin cytoskeleton	23
molecular level	23
thyroid hormone	23
blood vessels	23
neural activities	23
lapse imaging	23
nucleic acids	23
infrared spectroscopy	23
high frequency	23
submucosal glands	23
expression profiles	23
adult rats	23
cell lysis	23
transfection efficiency	23
serum albumin	23
expressing gfp	23
play important	23
monoclonal antibody	23
confidence level	23
lung tissue	23
fear memory	23
respiratory disease	23
glutamate uptake	23
three times	23
cd hi	23
asl height	23
gfp fluorescence	23
rhesus macaques	23
bl mice	23
cancer cells	23
result suggests	23
er stress	23
standard deviation	23
experiments showed	22
ak ub	22
liquid interface	22
control subjects	22
firefly luciferase	22
bd biosciences	22
pcr analysis	22
enteric tropism	22
previously demonstrated	22
newborn screening	22
enveloped viruses	22
os cells	22
mm hepes	22
weight loss	22
gene encoding	22
synaptic vesicles	22
keio univ	22
low temperature	22
studies using	22
adult rat	22
neural progenitor	22
recombinant virus	22
allow us	22
studies indicate	22
oligodendrocyte precursor	22
east respiratory	22
synthetic viruses	22
specific binding	22
riken bsi	22
proinflammatory cytokines	22
receptor activation	22
still unclear	22
may reflect	22
two weeks	22
different time	22
infectious virus	22
using two	22
respiratory symptoms	22
dorsal horn	22
time point	22
determined using	22
brain activity	22
rna virus	22
high affinity	22
statistically significant	22
working memory	22
future studies	22
statistical analysis	22
cell patch	22
disease progression	22
gene transcription	21
motor learning	21
subventricular zone	21
unilamellar vesicles	21
na absorption	21
pathological conditions	21
fos expression	21
animals vaccinated	21
cell division	21
rem sleep	21
sodium channel	21
evidence suggests	21
virus entry	21
kindly provided	21
ca influx	21
analyzed using	21
biofilm formation	21
hours post	21
respiratory epithelial	21
supplementary table	21
bronchoalveolar lavage	21
alveolar macrophages	21
synaptic inputs	21
increased expression	21
action potential	21
quantitative rt	21
chadox gfp	21
tight junctions	21
gene silencing	21
surround suppression	21
like receptor	21
epidemic diarrhea	21
th percentile	21
infectious clone	21
glutamate release	21
stem progenitor	21
protein aggregates	21
broad spectrum	21
motor cortex	21
slice cultures	21
liver disease	21
input neurons	21
antiviral compounds	21
inflammatory cytokine	21
functional significance	21
studies showed	21
will provide	21
lung transplant	21
mice exhibited	21
reporter genes	21
physical activity	21
bovine respiratory	20
western blots	20
also showed	20
mice lacking	20
present results	20
neuronal cells	20
labeled cells	20
small number	20
embryonic day	20
primary motor	20
neuronal damage	20
cftr trafficking	20
ablv replication	20
sciatic nerve	20
presynaptic terminals	20
equine encephalitis	20
open reading	20
years old	20
granule cell	20
active site	20
three days	20
cftr mutations	20
present work	20
schwann cell	20
antennal lobe	20
recombination events	20
well plate	20
genes involved	20
current study	20
central role	20
cultured cells	20
risk factors	20
da neurons	20
transmitter release	20
largely unknown	20
assessed using	20
healthy subjects	20
human immunodeficiency	20
potential difference	20
mature form	20
cells may	20
cells well	20
posterior lateral	20
differentially expressed	20
protein level	20
mdck cells	20
results demonstrated	20
dna nanoparticles	20
nagoya univ	20
reverse transcriptase	20
takes place	20
data obtained	20
per year	20
analysis using	20
heat shocked	20
essential role	20
transmissible gastroenteritis	20
inhibitory effects	20
empty vector	20
nucleotide binding	20
college london	20
related diabetes	20
small molecules	20
adult male	20
derived neurotrophic	19
significantly greater	19
drg neurons	19
fold higher	19
potential therapeutic	19
cells receive	19
poliovirus infection	19
male rats	19
mature oligodendrocytes	19
brain research	19
ebola virus	19
water maze	19
pancreatic insufficiency	19
host defense	19
preliminary data	19
early postnatal	19
short circuit	19
conformational change	19
peripheral er	19
dominant negative	19
synapse formation	19
stranded dna	19
molecular layer	19
will allow	19
study aimed	19
host factors	19
showed significant	19
elp tag	19
transmembrane domain	19
cell layer	19
nerve regeneration	19
egfp reporter	19
ependymal cells	19
ionizing radiation	19
dynamic light	19
chikv nsp	19
host cells	19
provide evidence	19
neuronal migration	19
primary human	19
optical imaging	19
increased levels	19
hydrogen peroxide	19
lung epithelial	19
higher levels	19
host interactions	19
glioma cells	19
new york	19
quantitative analysis	19
alternative splicing	19
physiological role	19
clinic visits	19
using anti	19
binding motifs	19
protein complexes	19
sindbis virus	19
significant reduction	19
immunohistochemical analysis	19
electrical stimulation	19
target proteins	19
glial activation	19
virus type	19
metropolitan institute	19
pediatric patients	19
modifier genes	19
glial scar	19
venezuelan equine	18
poly i	18
antiviral state	18
membrane expression	18
root ganglion	18
peripheral nervous	18
antimicrobial peptides	18
binding domains	18
three independent	18
outer membrane	18
significantly inhibited	18
primary microglia	18
molecule fluorescence	18
gfp positive	18
secretory pathway	18
clinically stable	18
actin filaments	18
hepg cells	18
food intake	18
sars coronavirus	18
increased risk	18
evaluated using	18
ifit proteins	18
recent study	18
protective effect	18
viral particles	18
may represent	18
drosophila melanogaster	18
inner ear	18
phase transition	18
also show	18
quantitative pcr	18
viral infections	18
cell sorting	18
one week	18
generated using	18
adhesion molecules	18
cell lysates	18
synaptic activity	18
cell population	18
early stages	18
new insights	18
virus titer	18
studies suggest	18
postnatal development	18
renilla luciferase	18
oligodendrocyte progenitor	18
mice compared	18
fetal bovine	18
viral vectors	18
lipid droplet	18
novel therapeutic	18
brain areas	18
beneficial effects	18
new method	18
throughput screening	18
somatosensory cortex	18
may help	18
peripheral nerve	18
also used	18
axon terminals	18
visualized using	18
read counts	18
neuronal function	18
facs analysis	18
activated protein	18
data support	18
fluorescently labeled	18
peripheral blood	17
gfp cells	17
plasmid dna	17
positively charged	17
encephalomyelitis virus	17
fmri study	17
environmental factors	17
chronic lung	17
vaccinated mice	17
scanning microscopy	17
frontal cortex	17
control animals	17
expression system	17
diarrhea virus	17
green fluorescence	17
vaccine candidate	17
treated rats	17
present data	17
resonance energy	17
individual neurons	17
cell body	17
mice treated	17
receptive fields	17
four hours	17
cells stably	17
membrane properties	17
mouse line	17
two days	17
energy metabolism	17
specific antibodies	17
receptor agonist	17
antiviral effects	17
scar formation	17
acid residues	17
ca channel	17
nuclear export	17
physiological sciences	17
wnt signaling	17
control groups	17
per well	17
cftr chloride	17
single channel	17
useful tool	17
different concentrations	17
double stranded	17
mrna splicing	17
japan science	17
ca signals	17
pcr using	17
therapeutic targets	17
powerful tool	17
neuronal network	17
main calyx	17
using fluorescence	17
chifit gene	17
physical properties	17
clinical symptoms	17
expression profile	17
hbe cells	17
atpase activity	17
closely related	17
atp binding	17
functional roles	17
processing site	17
mice using	17
neutrophil elastase	17
developing brain	17
encephalitis virus	17
model systems	17
highly conserved	17
inflammatory mediators	17
proteins involved	17
sensitive dye	17
cortical areas	17
rat spinal	17
studies indicated	17
adhesion molecule	17
directed mutagenesis	17
protein production	17
health care	17
istituto di	16
cultured cortical	16
reading frame	16
eiav infection	16
blood cells	16
dipartimento di	16
fluorescence correlation	16
experimental conditions	16
high resolution	16
dna fragments	16
protease inhibitor	16
hospital admission	16
also examined	16
tokyo medical	16
virulence factors	16
base pairs	16
high level	16
cell counts	16
life sci	16
cognitive function	16
mammalian expression	16
recombinant protein	16
neurodegenerative disease	16
secondary antibody	16
photon microscopy	16
allows us	16
estrogen receptor	16
axonal regeneration	16
semliki forest	16
therapeutic target	16
axonal transport	16
hearing loss	16
mm edta	16
fat mass	16
analysis demonstrated	16
nuclear translocation	16
therapeutic strategy	16
induced sputum	16
log likelihood	16
hek cells	16
autophagy pathway	16
proteolytic cleavage	16
two main	16
similar results	16
mechanical properties	16
recombinant proteins	16
gray matter	16
diabetes mellitus	16
cd cells	16
fully understood	16
recent years	16
ms ms	16
barr virus	16
ussing chamber	16
rat model	16
inflammatory markers	16
clamp recordings	16
pharmaceutical sciences	16
axon guidance	16
fluid secretion	16
primary cultured	16
cerebral ischemia	16
hippocampal formation	16
basic protein	16
quantified using	16
final concentration	16
virus particles	16
young adults	16
es cells	16
stop codon	16
visual system	16
chikv replication	16
barrel cortex	16
data analysis	16
different brain	16
eye movement	16
eye movements	16
aqueous extract	16
control samples	16
free protein	16
hokkaido university	16
medical science	16
niigata university	16
may explain	16
virus infections	16
lipid composition	16
brain sci	15
cerebellar cortex	15
radial glia	15
ne activity	15
scientific research	15
proteomic analysis	15
postsynaptic currents	15
mutant cftr	15
neural progenitors	15
axonal degeneration	15
middle cerebral	15
well tolerated	15
high concentrations	15
cultured hippocampal	15
city university	15
cytokine production	15
family members	15
autophagosome formation	15
per patient	15
lavage fluid	15
spatial frequency	15
stable expression	15
patients without	15
conditioned medium	15
studied using	15
visual stimuli	15
channel function	15
resonance imaging	15
replication complex	15
cepacia complex	15
rat hippocampus	15
ace cells	15
virus titers	15
primary antibodies	15
low levels	15
body image	15
neural cell	15
bhk cells	15
cell lysate	15
structural basis	15
recombinant viruses	15
results also	15
replication kinetics	15
kyushu institute	15
neural development	15
soluble form	15
neuronal survival	15
lung transplantation	15
therapeutic strategies	15
cells express	15
human cell	15
predicted fev	15
microglia macrophages	15
will present	15
morris water	15
positive neurons	15
underlying mechanisms	15
spatial memory	15
glial cultures	15
remains unknown	15
length cdna	15
nucleolar accumulation	15
within min	15
changes induced	15
pa infection	15
data suggests	15
contraction rate	15
small interfering	15
neural mechanisms	15
artery occlusion	15
like behavior	15
study suggests	15
kg day	15
female mice	15
cerebral artery	15
tumor cells	15
percent predicted	15
unclear whether	15
memory formation	15
mrna level	15
delivered dose	15
percent change	15
associated protein	15
pari lc	15
vitro transcription	15
neural cells	15
cultured neurons	15
steady state	15
ribosomal rna	15
fever virus	15
live imaging	15
biological systems	15
viral titers	15
lung pathology	15
force spectroscopy	15
flow rate	15
vesicular glutamate	15
blood samples	15
forest virus	15
ifit gene	15
wt cells	15
microglial cell	15
primary visual	15
ganglion cells	15
blood glucose	15
firing rate	15
ventral accessory	15
cell signaling	14
may serve	14
growth cones	14
na channels	14
cftr activation	14
labeled neurons	14
body mass	14
vivo imaging	14
protein structure	14
chloride currents	14
tidal volume	14
rna degradation	14
imperial college	14
excitatory synapses	14
cftr tm	14
antiviral properties	14
astroglial cells	14
motor function	14
imaging techniques	14
previous reports	14
neural circuit	14
serous cells	14
cell survival	14
protein interaction	14
mammalian cell	14
untreated cells	14
neuronal loss	14
cell responses	14
wt littermates	14
cultured rat	14
medical sciences	14
translation inhibition	14
orf protein	14
olfactory system	14
escherichia coli	14
iodide efflux	14
glucose tolerance	14
electron microscopic	14
viral mrna	14
even though	14
hepatitis virus	14
using different	14
normal human	14
serum levels	14
healthy volunteers	14
major role	14
behavioral abnormalities	14
high throughput	14
fluorescence imaging	14
examine whether	14
quantitative real	14
technology agency	14
poorly characterized	14
mammalian brain	14
psychiatric disorders	14
body composition	14
electrical activity	14
cells grown	14
surface area	14
chicken embryos	14
adverse events	14
twice daily	14
ifit genes	14
hippocampal slice	14
catalytically inactive	14
ussing chambers	14
without affecting	14
physical chemistry	14
adult mouse	14
individual cells	14
bacterial infection	14
genes encoding	14
serial dilutions	14
ad mice	14
successfully used	14
purified rsv	14
cdna clone	14
ml min	14
chloride secretion	14
whole brain	14
induced changes	14
bacterial killing	14
developmental stages	14
target protein	14
italian institute	14
virus genome	14
possible role	14
like structures	14
clinical trial	14
study investigated	14
tissue sections	14
pabrh cells	14
also increased	14
class ii	14
cftr inhibitor	14
also suggest	14
potassium channels	14
lc plus	14
myosin ii	14
vivo studies	14
cos cells	14
critical period	14
agarose gel	14
replication complexes	14
also investigated	14
firing patterns	14
authors declare	14
vaccinated animals	14
patients compared	14
functional properties	14
whole sputum	14
based assay	14
infectious diseases	14
spinal cords	14
human ifit	14
yellow fluorescent	14
fold change	14
medial prefrontal	14
model membranes	14
recently identified	14
washed twice	14
normal brain	14
aptamer chimera	14
dna damage	14
protein aggregation	14
pa pf	14
might play	14
detected using	14
mouse lung	14
raman spectroscopy	14
well defined	13
binding activity	13
differ significantly	13
registry data	13
cell populations	13
chiba university	13
viral proteases	13
biological membranes	13
studies demonstrate	13
studies revealed	13
cytopathic effect	13
rpe cells	13
calcium channels	13
specific peaks	13
host shutoff	13
chicken ifit	13
term memory	13
mixed glial	13
tested whether	13
neurodegenerative disorder	13
fluorescent molecules	13
ca signaling	13
may result	13
myelin basic	13
peripheral nerves	13
luciferase reporter	13
translation initiation	13
close proximity	13
eukaryotic cells	13
function tests	13
gene editing	13
cerebellar nuclei	13
fibril formation	13
three different	13
di fisica	13
forced expiratory	13
provide new	13
na i	13
experiments show	13
cellular functions	13
imaging system	13
one hour	13
surface antigen	13
new therapies	13
myeloid cells	13
lineage cells	13
gastrostomy tube	13
quality improvement	13
ischemic injury	13
tokyo university	13
skeletal muscle	13
total cell	13
subcellular localization	13
interfering rna	13
using single	13
single dose	13
south korea	13
vitro studies	13
related genes	13
confocal images	13
goat anti	13
enzyme activity	13
significantly larger	13
infectious cdna	13
visual field	13
pivotal role	13
start site	13
cftr maturation	13
neural circuits	13
tyrosine hydroxylase	13
functional analysis	13
stress response	13
neurons may	13
nihon university	13
genetic counseling	13
influenza viruses	13
give rise	13
blood flow	13
viral envelope	13
sox targeting	13
subgenomic promoter	13
ventricular zone	13
field potential	13
neuroblastoma cell	13
washed three	13
glial fibrillary	13
experimental autoimmune	13
activity using	13
synaptic vesicle	13
specific manner	13
basal cells	13
mechanisms involved	13
binding affinity	13
cingulate cortex	13
statistical significance	13
using fmri	13
underlying mechanism	13
cells also	13
public health	13
also demonstrated	13
also significantly	13
significant effect	13
dengue virus	13
amyotrophic lateral	13
error bars	13
antiviral effect	13
cho cells	13
cerebellar purkinje	13
recent advances	13
anterior cingulate	13
derived macrophages	13
fold greater	13
three groups	13
optic lobe	13
cx cl	13
median age	13
functional studies	13
crispr cas	13
nsp binds	13
coupled receptors	13
human genome	13
lipid membrane	13
waseda university	13
chronic inflammation	13
mouse monoclonal	13
channel gating	13
cov strains	13
nerve terminals	13
complex formation	13
consensus sequence	13
human lung	13
also expressed	13
cortical slices	13
young adult	13
stab wound	13
healthy children	13
examined using	13
staphylococcus aureus	13
flavoprotein fluorescence	13
pulmonary infection	13
slice culture	13
patient registry	13
also shown	13
open field	13
therapeutic potential	13
transmission electron	13
cell entry	13
several types	13
protective role	13
lateral sclerosis	13
study demonstrates	13
oligodendrocyte lineage	13
significant role	13
markedly increased	13
activated cell	13
astrocyte activation	13
like cells	13
neurodegenerative disorders	13
protease inhibitors	13
layer neurons	12
spontaneous activity	12
mitsubishi kagaku	12
postsynaptic density	12
receptor expression	12
neuronal activities	12
cftr mutation	12
baseline fev	12
spatial distribution	12
luciferase activity	12
also detected	12
type littermates	12
using primers	12
concentration range	12
proteolytic activity	12
binocular disparity	12
different stages	12
mental retardation	12
using lipofectamine	12
neurotransmitter release	12
first year	12
completely abolished	12
hokkaido univ	12
mice deficient	12
airway mucus	12
expanded polyglutamine	12
neuronal networks	12
ray scattering	12
cbx cells	12
protein family	12
constitutively active	12
aged mice	12
arachidonic acid	12
opc migration	12
nakai extracts	12
state university	12
transgenic chicken	12
fold decrease	12
superior lateral	12
pdz domain	12
clamp recording	12
ferulic acid	12
increased significantly	12
nonstructural protein	12
dorf gfp	12
secondary antibodies	12
serially diluted	12
soluble protein	12
brain slice	12
kainic acid	12
provide novel	12
intracellular trafficking	12
cftr inh	12
cfu ml	12
lung infection	12
cell transplantation	12
aeruginosa infection	12
also performed	12
used two	12
proteins using	12
chromatin binding	12
vas deferens	12
programmed cell	12
mrna degradation	12
rabies virus	12
extracellular virus	12
factor receptor	12
sensorimotor cortex	12
medical research	12
time constant	12
er ca	12
confocal fluorescence	12
see table	12
xenopus oocytes	12
will help	12
nt surrounding	12
ionic strength	12
associative learning	12
protein dynamics	12
i cl	12
activated astrocytes	12
injected mice	12
broad range	12
almost completely	12
layer pyramidal	12
cdna clones	12
high dose	12
amiloride sensitive	12
optical tweezers	12
plexiform layer	12
processing sites	12
protein nanoparticle	12
marked increase	12
dental university	12
significant improvements	12
neurons using	12
specific gene	12
various cell	12
analyses revealed	12
lung infections	12
like protein	12
regulatory elements	12
ion channel	12
year post	12
virus expressing	12
health outcomes	12
identified several	12
ampa receptor	12
viral receptors	12
ca channels	12
breast cancer	12
luciferase gene	12
immunoblot analysis	12
nasal potential	12
neuronal circuits	12
candidate genes	12
extracellular space	12
neuroprotective effect	12
cftr null	12
surface proteins	12
type ca	12
cortical astrocytes	12
cognitive functions	12
nutritional risk	12
gfap expression	12
temporal lobe	12
terminal region	12
mossy fibers	12
chronic infection	12
immune cell	12
may affect	12
newcastle disease	12
mainly due	12
tyrosine kinase	12
gfp infected	12
markedly reduced	12
nippon medical	12
plant cells	12
reactive astrogliosis	12
myelinating cells	12
good agreement	12
will also	12
necrosis factor	12
frontal gyrus	12
membrane fluidity	12
transepithelial resistance	12
well characterized	12
virus infected	12
gene mutations	12
myelin protein	12
might contribute	12
clinic visit	12
induced apoptosis	12
cftr channel	12
cell recordings	12
current response	12
cvb infection	12
medium supplemented	12
per group	12
emission spectra	12
cftr promoter	12
virus infectivity	12
many patients	12
inferior temporal	12
molecular interactions	12
wall redundancy	12
culture supernatant	12
myelin sheath	12
kenyon cell	12
regulatory mechanisms	12
chronic pain	12
human neuroblastoma	12
local field	12
serine protease	12
terminal fragment	12
transcriptional regulation	12
neutron scattering	12
experimental results	12
cftr cells	12
advance care	12
protein quality	12
colonic wall	12
optical signal	12
gene product	12
mutant protein	12
least three	12
lesion site	12
red blood	12
mm mgcl	12
much higher	12
isg mutants	12
monoclonal antibodies	12
transgenic line	12
protein unfolding	12
clamp technique	12
neuronal functions	12
mice expressing	12
integral membrane	11
reporter viruses	11
mesenchymal stem	11
receptor subunits	11
brain tissues	11
autoimmune encephalomyelitis	11
higher brain	11
parietal cortex	11
sensory inputs	11
muscle activity	11
specific inhibitor	11
antibiotic use	11
neuronal development	11
cell growth	11
sample size	11
primary auditory	11
imaging microscopy	11
acidic protein	11
active zone	11
mathematical model	11
plaque assay	11
delivery system	11
study demonstrated	11
disease complex	11
nerve fibers	11
sirna delivery	11
chloride ion	11
targeted rna	11
viral diseases	11
brain activation	11
receptor antagonists	11
firing rates	11
dmem medium	11
data provide	11
differential expression	11
analysis indicated	11
jak stat	11
uller glial	11
excitatory postsynaptic	11
transmembrane domains	11
enabled us	11
phase ii	11
treated group	11
randomly selected	11
coli cell	11
signaling molecules	11
significantly enhanced	11
mutant mouse	11
progenitor cell	11
viral life	11
md simulations	11
cell shrinkage	11
poliovirus proteins	11
increasing evidence	11
antimicrobial activity	11
promoter activity	11
locus coeruleus	11
gunma univ	11
reverse primer	11
chloride concentration	11
sweat test	11
low concentrations	11
chicken genome	11
firing pattern	11
mucus obstruction	11
niigata univ	11
amplified using	11
basic research	11
significant correlation	11
using antibodies	11
predominantly expressed	11
complex i	11
time rt	11
sequences surrounding	11
membraned vesicles	11
cell response	11
using immunohistochemistry	11
university hospital	11
severe lung	11
scanning microscope	11
cftr mediated	11
replication cycle	11
alexa fluor	11
stratum radiatum	11
cell fate	11
team members	11
lung lobes	11
hiroshima university	11
using whole	11
matched controls	11
potential role	11
san francisco	11
significant change	11
chain length	11
cultured astrocytes	11
biophysical chemistry	11
fluorescent probes	11
japan recent	11
ca area	11
physiological roles	11
dorf rluc	11
tissue damage	11
study using	11
signalling molecules	11
mushroom bodies	11
bath application	11
lung inflammation	11
clinical care	11
sds page	11
different sites	11
past years	11
virus strain	11
synthesis system	11
mitochondrial membrane	11
experiments revealed	11
antiviral agents	11
near infrared	11
modified vaccinia	11
intravenous antibiotics	11
rna molecules	11
smooth pursuit	11
mrna translation	11
protein trafficking	11
specific role	11
via activation	11
much lower	11
microglial processes	11
results will	11
also reduced	11
male wistar	11
gland secretion	11
traumatic brain	11
new therapeutic	11
intracellular distribution	11
gastroenteritis virus	11
cff registry	11
muscle contraction	11
inflammatory genes	11
delivery systems	11
short term	11
physiologically relevant	11
projection neuron	11
spatial resolution	11
neurons projecting	11
bile flow	11
inflammatory cells	11
containing mm	11
reporter virus	11
page gel	11
possible involvement	11
direct interaction	11
single neuron	11
potential target	11
chondroitin sulfate	11
calcium signaling	11
transient expression	11
transient increase	11
elevated plus	11
calcium imaging	11
subviral particles	11
median fev	11
temperature corrected	11
synaptic terminals	11
transport activity	11
protein translation	11
study aims	11
immunoglobulin superfamily	11
specific promoters	11
facial nerve	11
treatment groups	11
observations suggest	11
alzheimer disease	11
neutrophil recruitment	11
buffered saline	11
wildtype mice	11
days later	11
neuronal dysfunction	11
single stranded	11
bergmann glia	11
expression analysis	11
assay using	11
ng dl	11
genome replication	11
mitochondrial dysfunction	11
control conditions	11
reverse transcription	11
axonal growth	11
significantly less	11
early phase	11
differentiated respiratory	11
wide variety	11
multiplicative factor	11
inhibitory synapses	11
titration calorimetry	11
transforming growth	11
results support	11
heparan sulfate	11
demyelinating diseases	11
life technologies	11
lung tx	11
mediated activation	11
clinical isolate	11
signalling pathways	11
done using	11
expiratory volume	11
many aspects	11
dependent protein	11
protease activity	11
spatial learning	11
radiation exposure	11
cell volume	11
north carolina	11
resting membrane	11
respiratory scale	11
previously found	11
sequence analysis	11
full length	11
positively correlated	11
genetics system	11
several studies	11
current density	11
optical microscopy	11
johns hopkins	11
basolateral membrane	11
di biofisica	11
interferon response	11
burkholderia cepacia	11
confocal imaging	10
drug design	10
phase separation	10
least two	10
induced vesicles	10
field potentials	10
also included	10
fluorescent markers	10
positive astrocytes	10
vast majority	10
imaging experiments	10
various time	10
contextual fear	10
planck institute	10
respiratory medicine	10
complete medium	10
functional expression	10
specific interaction	10
containing fbs	10
pen strep	10
clinical studies	10
iv antibiotic	10
superoxide dismutase	10
grey matter	10
fourier transform	10
postnatal week	10
surface charge	10
currently investigating	10
pd patients	10
four times	10
showed increased	10
recently shown	10
conserved across	10
transgenic rats	10
spike gene	10
various types	10
area te	10
natural isolates	10
miu ml	10
receptor signaling	10
action selection	10
purinergic signaling	10
protective immunity	10
demyelinated axons	10
epigenetic regulators	10
electrophysiological recordings	10
electric field	10
sybr green	10
two components	10
swine fever	10
hemichannel activity	10
brain region	10
temporal order	10
inhibitory synaptic	10
fat diet	10
recognition particle	10
high efficiency	10
clinical signs	10
cell differentiation	10
crucial roles	10
embryonic stem	10
weeks post	10
motor nucleus	10
phev replication	10
biological processes	10
water molecules	10
slice preparations	10
laser irradiation	10
il tg	10
three weeks	10
temporal patterns	10
takeshi kaneko	10
neonatal rat	10
fl fl	10
giant unilamellar	10
glioma cell	10
study examined	10
one year	10
brain damage	10
mucous cells	10
aggregate formation	10
xenopus laevis	10
fxyd expression	10
data also	10
formic acid	10
aureus virulence	10
bmp signaling	10
may act	10
wound healing	10
vice versa	10
immune evasion	10
reactive microglia	10
fluorescence microscope	10
gfp knock	10
dmem containing	10
chain reaction	10
protein binding	10
neuronal excitability	10
inhibitory neurons	10
adult neurogenesis	10
possible mechanism	10
opc proliferation	10
fibrosis center	10
nipah virus	10
ct scans	10
neuronal circuit	10
care centers	10
previously showed	10
genetic material	10
alkaline phosphatase	10
poliovirus rna	10
neural mechanism	10
microscopy revealed	10
pdb id	10
discrimination task	10
oligodendroglial exosomes	10
associated proteins	10
single molecules	10
studies also	10
neuronal processes	10
diseases including	10
kakenhi sy	10
identified novel	10
liposomal amikacin	10
single nucleotide	10
active form	10
dependent mechanism	10
physiological functions	10
microglial response	10
two cell	10
adult cystic	10
cell biol	10
consecutive days	10
cellular responses	10
iii secretion	10
kda protein	10
stably expressed	10
structural properties	10
isothermal titration	10
glia cells	10
sciatic nerves	10
uller glia	10
response properties	10
months old	10
bal fluid	10
investigated using	10
lifetime imaging	10
may influence	10
channel inhibitor	10
patients completed	10
cftr folding	10
airway infection	10
neural responses	10
gfp infection	10
aggregation process	10
primary culture	10
restriction site	10
retrospective study	10
orientation maps	10
mice overexpressing	10
cd expression	10
gram negative	10
photon excitation	10
na transport	10
assess whether	10
electronic nebulizer	10
matrix protein	10
cell synapses	10
actin polymerization	10
glucose deprivation	10
cell attachment	10
neutralizing antibody	10
genbank accession	10
japan previous	10
regulatory factor	10
regulatory proteins	10
expression cassette	10
page gels	10
reduced viral	10
passive avoidance	10
animal experiments	10
mature neurons	10
usa background	10
one patient	10
macaque monkeys	10
mouse embryos	10
fluorescence recovery	10
higher concentrations	10
objective lens	10
selective inhibitor	10
epidermal growth	10
cell number	10
chikv infection	10
median time	10
waiting list	10
human diseases	10
cortical cells	10
mice show	10
geniculate nucleus	10
nucleocapsid protein	10
envelope proteins	10
superior colliculus	10
hela cell	10
brain sections	10
weight gain	10
structural information	10
motor area	10
ltp induction	10
molecule level	10
monocular deprivation	10
competing interests	10
study showed	10
cns injury	10
action plan	10
signal recognition	10
early visual	10
remain unclear	10
replacement therapy	10
negative bacteria	10
myelin sheaths	10
primary cells	10
human respiratory	10
memory extinction	10
mmp expression	10
positive feedback	10
olfactory epithelium	10
induced neuronal	10
visually guided	10
neuronal populations	10
fluorescent dye	10
stably transfected	10
i ifns	10
dna binding	10
binding partners	10
airway cells	10
nasal epithelium	10
primary astrocytes	10
inhaled tobramycin	10
human cftr	10
still unknown	10
boost regimen	10
pluripotent stem	10
will show	10
blood brain	10
cell metaplasia	10
different strategies	10
transiently expressed	10
fibrillary acidic	10
polyclonal antibody	10
protein tags	10
crystal structures	10
irt irt	10
double transgenic	10
also confirmed	10
single cells	10
drug discovery	10
experimental models	10
luciferase assay	10
classical swine	10
trypan blue	10
pancreatic insufficient	10
receptor binding	10
cftr inhibitors	10
es cell	10
social interaction	10
study will	10
also measured	10
cell monolayers	10
fear conditioning	10
drug development	10
functional cftr	10
animal care	10
optical properties	10
term depression	10
na channel	10
ec values	10
directly related	10
viral gene	10
small protein	10
dna sequencing	10
remains largely	10
mucous cell	10
per day	10
significantly smaller	10
radial migration	10
mass index	10
fixation point	10
cultured microglia	10
nih grant	10
elevated levels	10
antiviral immunity	10
structural integrity	10
oral glucose	10
fluorescence resonance	10
oxygen saturation	10
reporter mice	10
scale bar	10
premotor cortex	10
insular cortex	10
critical roles	10
temperature correction	10
cell extracts	10
may induce	10
data reveal	9
sensor cell	9
globus pallidus	9
two independent	9
major component	9
cells expressed	9
substrate specificity	9
airway secretions	9
ali cultures	9
cfbe ocells	9
oligodendrocyte development	9
neurological diseases	9
like particles	9
mean change	9
optic nerves	9
cancer cell	9
phase i	9
wt cftr	9
mucociliary transport	9
may offer	9
positron emission	9
interacting protein	9
ii pneumocytes	9
three viruses	9
open probability	9
nuclear bodies	9
plus maze	9
surface protein	9
time window	9
previous work	9
reversal potential	9
cells following	9
serum il	9
jet nebulizer	9
also analyzed	9
also suggested	9
parkinson disease	9
results confirm	9
chicken embryo	9
capsid protein	9
asked whether	9
raphe nuclei	9
signalling pathway	9
research foundation	9
case western	9
derived cell	9
water permeability	9
entorhinal cortex	9
structural features	9
ips cells	9
also studied	9
coding sequence	9
pkc phosphorylation	9
culture supernatants	9
late phase	9
frequency stimulation	9
serous acinar	9
chronically infected	9
national institutes	9
motor neuron	9
jikei univ	9
disease onset	9
powerful tools	9
conditioned media	9
olfactory learning	9
specific primers	9
normal mice	9
receptor mediated	9
newly generated	9
aedes albopictus	9
hl cells	9
contains two	9
vitro model	9
observation period	9
huntington disease	9
linear regression	9
cftr mice	9
spine density	9
polymerase chain	9
financial support	9
small airways	9
findings show	9
opc maturation	9
temporal resolution	9
western reserve	9
gal transgenic	9
oscillatory activity	9
bronchial epithelia	9
motor activity	9
dynamical properties	9
analyses showed	9
unadjusted height	9
neuron activity	9
lipid vesicles	9
low ph	9
various brain	9
fluorescence anisotropy	9
ts cje	9
volume regulation	9
clinical outcomes	9
healthy control	9
second cleavage	9
animals showed	9
highly specific	9
irt dna	9
phosphorylation sites	9
significantly improved	9
molecule force	9
biological activity	9
currently available	9
genetically encoded	9
diffusion coefficient	9
stimulated genes	9
lipid rafts	9
auditory system	9
astroglial networks	9
one day	9
cov cl	9
envelope protein	9
four different	9
many viruses	9
high concentration	9
previously published	9
well documented	9
conducted using	9
pka phosphorylation	9
gfp mice	9
life expectancy	9
containing either	9
two years	9
vaccine carrier	9
hispanic patients	9
primary rat	9
fluorescent microscopy	9
mm nh	9
recent work	9
unfolded protein	9
protect neurons	9
mediated endocytosis	9
sucrose cushion	9
acute slices	9
computer simulation	9
association cortex	9
footpad swelling	9
radial glial	9
intracellular ph	9
egfp mice	9
defective cftr	9
data showed	9
inward current	9
second step	9
inflammatory phenotype	9
data will	9
chase experiments	9
fluorescence emission	9
shrna expression	9
axon regeneration	9
essential cellular	9
rapid decline	9
adult neural	9
human coronavirus	9
significantly attenuated	9
dromedary camels	9
cellular proteins	9
targeted gene	9
preliminary experiments	9
guidance molecules	9
potassium channel	9
cell therapy	9
group showed	9
molecular neurobiology	9
recorded neurons	9
two patients	9
lateral geniculate	9
generated transgenic	9
frontier biosciences	9
sialic acid	9
mediated cl	9
specific antibody	9
imaged using	9
cells isolated	9
monitor virus	9
gfp mrna	9
olfactory information	9
repeated measures	9
ca stores	9
also involved	9
bee venom	9
control diet	9
foundation therapeutics	9
well established	9
lung tissues	9
recent reports	9
restriction factor	9
graphpad prism	9
body temperature	9
tight junction	9
camp pka	9
psd fraction	9
forming cells	9
probably due	9
paraventricular nucleus	9
domestic cat	9
free medium	9
czech republic	9
shock protein	9
df cftr	9
respiratory rhythm	9
induced nucleolar	9
ischemic conditions	9
correlation coefficient	9
nm ii	9
injury site	9
nsp binding	9
cftr mrna	9
gsh levels	9
pancreatic status	9
clinical outcome	9
patient care	9
cell infiltration	9
active lesions	9
strongly suggest	9
cognitive decline	9
emission tomography	9
dorsal part	9
took advantage	9
brain res	9
mobility shift	9
defense mechanism	9
signal intensity	9
genomic rna	9
superior temporal	9
neuroprotective effects	9
short stature	9
virucidal activity	9
lower levels	9
del mutation	9
dependent plasticity	9
resident macrophages	9
brain tumors	9
brain functions	9
essential roles	9
human patients	9
autophagy activation	9
acinar cells	9
greatly reduced	9
following treatment	9
nasal airway	9
thermo scientific	9
memory consolidation	9
mice revealed	9
previous findings	9
oxidative damage	9
attenuated vaccine	9
juntendo univ	9
leading cause	9
well described	9
old rats	9
cftr potentiators	9
soluble receptor	9
protein response	9
transport properties	9
recent progress	9
calculated using	9
model using	9
expressed genes	9
axon growth	9
targeting element	9
nervous systems	9
days old	9
sleep deprivation	9
specifically expressed	9
culture systems	9
right hemisphere	9
chronic inflammatory	9
ffu ml	9
step towards	9
recently demonstrated	9
chart review	9
prospective study	9