quadgram

This is a table of type quadgram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

quadgram frequency
these results suggest that242
in the presence of211
in the present study150
on the other hand90
the central nervous system90
in the absence of87
these results indicate that86
an important role in86
of this study was83
results suggest that the80
this study was to80
in vitro and in77
as well as the74
vitro and in vivo72
in the regulation of68
we found that the68
has been shown to68
our results suggest that65
the dorsal accessory calyx64
graduate school of medicine63
the aim of this60
these data suggest that58
a bp kenyon cells56
can be used to52
is one of the52
play a role in52
of angelica tenuissima nakai51
aim of this study51
play an important role49
little is known about46
university graduate school of46
for the treatment of45
patients with cystic fibrosis45
in the central nervous44
in this study we44
we have shown that42
these findings suggest that42
have been shown to41
in patients with cf40
severe acute respiratory syndrome40
plays an important role39
as well as in39
at the end of39
on the basis of39
a significant increase in38
the presence of a38
is involved in the37
university school of medicine36
for the first time36
one of the most36
our results indicate that35
had no effect on35
cells were infected with35
the end of the35
black flying fox cells35
in the number of33
in the spinal cord32
we have previously shown32
examined the effects of32
be involved in the32
in the case of32
to be involved in32
the a bp kenyon31
purpose of this study31
important role in the31
cystic fibrosis transmembrane conductance31
the present study was30
under the control of30
our results show that30
fibrosis transmembrane conductance regulator30
a wide range of30
a large number of30
the role of the30
as a function of30
the results suggest that30
in the development of29
of the central nervous29
the purpose of this29
as a result of29
the presence of the29
here we show that29
was observed in the29
studies have shown that29
was used as a29
is known to be28
been shown to be28
a member of the28
we have developed a28
a role in the28
was found to be28
at the time of28
for the development of28
it has been shown27
we also found that27
have previously shown that27
we were able to26
we show that the26
the total number of26
of this study is26
is known about the26
results indicate that the26
riken brain science institute26
our data suggest that26
acute respiratory syndrome coronavirus26
investigated the effect of25
is thought to be25
the expression of the25
a decrease in the25
we examined the effects25
in the pathogenesis of25
an increase in the25
this study is to24
this work was supported24
the cystic fibrosis transmembrane24
work was supported by24
investigated the effects of24
to the plasma membrane24
cells were transfected with23
examined the effect of23
a significant decrease in23
a better understanding of23
in the expression of23
a key role in23
as shown in figure23
a crucial role in23
hek t cells were23
by the presence of23
in patients with cystic23
may contribute to the22
the green fluorescent protein22
in addition to the22
did not affect the22
it was shown that22
to the development of22
middle east respiratory syndrome22
is a member of21
in contrast to the21
in the plasma membrane21
in the ca region21
in the treatment of21
the formation of the21
cells were treated with21
on the surface of21
has been shown that21
there was no significant21
in the control of21
sod g a mice20
these results suggested that20
it was found that20
as compared to the20
it is possible to20
of cf lung disease20
we have found that20
in the hippocampus of20
a critical role in20
human airway epithelial cells20
neutrophils and inflammatory monocytes20
r n a l19
increased the number of19
results show that the19
the posterior lateral protocerebrum19
extract of angelica tenuissima19
j o u r19
study was to investigate19
p r o o19
animals vaccinated with chadox19
the size of the19
data suggest that the19
in the substantia nigra19
plays a role in19
o u r n19
national institute for physiological19
in this work we19
cells were cultured in19
might be involved in19
r o o f19
east respiratory syndrome coronavirus19
no effect on the19
u r n a19
the aim of the19
a l p r19
in black flying fox19
role in the regulation19
the effect of the19
we have demonstrated that19
these results demonstrate that19
were found to be19
l p r e19
n a l p19
there was no difference18
we investigated the effect18
the basis of the18
may be involved in18
we examined the effect18
we investigated the effects18
we have investigated the18
in children with cf18
the function of the18
for the study of18
national institute of neuroscience18
it is important to18
to determine whether the18
the activity of the18
at the level of18
in the formation of18
at the plasma membrane18
was to investigate the18
investigate the effect of18
the present study we18
at the cell surface18
no significant difference in18
to better understand the18
porcine epidemic diarrhea virus17
at the same time17
play important roles in17
presence or absence of17
significant increase in the17
there was a significant17
it is possible that17
to the dorsal accessory17
to test this hypothesis17
were observed in the17
the cystic fibrosis foundation17
tokyo metropolitan institute for17
metropolitan institute for neuroscience17
the university of tokyo17
study was to determine17
in the context of17
institute for physiological sciences17
that there is a17
both in vitro and17
as well as to16
k cat k m16
it is known that16
the structure of the16
we have studied the16
we have reported that16
investigate the role of16
in the rat brain16
a small number of16
department of anatomy and16
the development of the16
the influence of the16
to the formation of16
it is well known16
the control of the16
are involved in the16
better understanding of the16
during the course of16
is based on the16
min at room temperature16
in the brain of16
the results showed that16
decline in lung function16
has been reported to16
with respect to the16
in the cerebral cortex16
japan science and technology16
at different time points16
we have previously reported16
kyushu institute of technology15
these results show that15
may play a role15
to investigate the effect15
of severe acute respiratory15
the objective of this15
has been used to15
was used to determine15
increase in the number15
was no difference in15
the surface of the15
the nucleolus after hs15
can be used for15
we conclude that the15
as shown in fig15
was added to the15
it has been reported15
of neurons in the15
the plasma membrane of15
for min at room15
in the dorsal accessory15
morbidity and mortality in15
was associated with a15
in the present work15
used to determine the15
it is likely that15
is well known that15
c bl j mice15
there were no significant14
aqueous extract of angelica14
cells were seeded in14
these data indicate that14
play a key role14
are known to be14
involved in the regulation14
have previously reported that14
school of pharmaceutical sciences14
is expressed in the14
results showed that the14
has been reported that14
as well as a14
these results indicated that14
during the study period14
the mechanism by which14
of the dentate gyrus14
of neural stem cells14
objective of this study14
human bronchial epithelial cells14
it has been suggested14
the presence or absence14
to the presence of14
we have examined the14
the time course of14
vaccinated with chadox gfp14
patients with cf and14
as one of the14
these findings indicate that14
in cf patients with14
used in this study14
gene expression in the14
were found in the14
of the present study14
were included in the14
cells were incubated with14
and the number of14
the development of a14
but not in the14
italian institute of technology14
the ventral accessory calyx13
the primary visual cortex13
at an moi of13
we found that a13
is consistent with the13
the regulation of the13
findings suggest that the13
by the cystic fibrosis13
the course of the13
the apical surface of13
here we report that13
in the pathophysiology of13
a final concentration of13
graduate school of science13
on the cell surface13
was also observed in13
in order to determine13
can be used as13
to an increase in13
in the olfactory bulb13
was no significant difference13
graduate school of pharmaceutical13
has been suggested that13
to play a role13
the formation of a13
the molecular mechanisms of13
was applied to the13
the magnitude of the13
in cystic fibrosis patients13
the relationship between the13
graduate school of medical13
one of the main13
is characterized by a13
in the dentate gyrus13
the expression level of13
in airway epithelial cells13
with fetal bovine serum13
in hek t cells13
supported by grants from13
science and technology agency13
the expression levels of13
the molecular mechanism of13
to the cell surface13
is the most common13
our data show that13
present study was to13
of the green fluorescent13
the molecular basis of13
aid for scientific research12
the position of the12
that the expression of12
the superior lateral protocerebrum12
the results show that12
is necessary for the12
the location of the12
a central role in12
middle cerebral artery occlusion12
it is not clear12
angelica tenuissima nakai extracts12
significant difference in the12
are consistent with the12
to the apical surface12
have shown that the12
to test the hypothesis12
vaccinated with chadox mers12
in the presence or12
at least in part12
has been proposed to12
as part of a12
as a positive control12
the effects of the12
through the activation of12
in the presence and12
our findings suggest that12
venezuelan equine encephalitis virus12
were obtained from the12
of science and technology12
of gaba a receptors12
at the surface of12
to be associated with12
plays a crucial role12
the functional role of12
we did not observe12
and the effect of12
using a combination of12
this is the first12
to the a bp12
in accordance with the12
we previously reported that12
cellular and molecular mechanisms12
to be expressed in11
tokyo university of agriculture11
were transiently transfected with11
may be due to11
was supported by the11
the use of the11
that the number of11
were no significant differences11
it was suggested that11
the left and right11
to that of the11
the functional significance of11
the mechanisms by which11
for the detection of11
as a consequence of11
the antiviral activity of11
the angelica tenuissima nakai11
compared to the control11
with an increase in11
have been used to11
in the nucleolus after11
japan it has been11
be due to the11
to be due to11
in agreement with the11
of central nervous system11
test the hypothesis that11
the viral life cycle11
in order to study11
the crystal structure of11
at the age of11
could be involved in11
a significant reduction in11
was detected with clone11
for the regulation of11
the spinal cord of11
with the use of11
a wide variety of11
in the hippocampal ca11
the innate immune response11
supplemented with fetal bovine11
the inhibitory effect of11
the importance of the11
may be related to11
data are consistent with11
in an attempt to11
is not well understood11
the molecular mechanisms underlying11
of bv or mlt11
positive cells in the11
graduate school of life11
over the course of11
we have previously demonstrated11
confocal laser scanning microscopy11
city university graduate school11
to address this issue11
in a variety of11
was used to measure11
previous studies have shown11
in the process of11
these results suggest the11
children with cystic fibrosis11
cf bronchial epithelial cells11
in a mouse model11
caused by mutations in11
one of the major11
our data demonstrate that11
neuronal activity in the11
in the vicinity of11
be one of the11
our results demonstrate that11
of children with cf11
membrane expression of cftr10
in the primary visual10
these data show that10
the onset of the10
of semliki forest virus10
to play an important10
school of life science10
by the addition of10
understand the role of10
here we report the10
this result suggests that10
we showed that the10
study was to evaluate10
was injected into the10
as well as their10
we are currently investigating10
classical swine fever virus10
the presence of two10
in cf patients and10
plays a key role10
the ability of the10
that the majority of10
the expression pattern of10
we have used a10
japan we examined the10
we sought to determine10
before and after the10
glial cells in the10
in cells infected with10
of the formation of10
of hepatitis b virus10
we will discuss the10
in the visual cortex10
by the expression of10
play a crucial role10
fluorescence resonance energy transfer10
an essential role in10
of a variety of10
goal of this study10
the apical membrane of10
in the cf lung10
aim of the present10
key role in the10
dopaminergic neurons in the10
experiments were performed in10
three times with pbs10
a significant difference between10
we demonstrate that the10
be used as a10
of respiratory syncytial virus10
differentiated respiratory epithelial cells10
these observations suggest that10
in the basal ganglia10
on the expression of10
in the majority of10
were used to determine10
a major role in10
free protein synthesis system10
compared to that of10
the possible role of10
was detected in the10
for the formation of10
and western blot analysis10
have previously demonstrated that10
have demonstrated that the10
cells were transiently transfected10
of the plasma membrane10
and some of them10
to investigate the role10
significant decrease in the10
in the brain and10
in situ hybridization and10
is likely to be10
the physiological role of10
is essential for the10
tokyo medical and dental10
and atomic force microscopy10
the length of the10
of morbidity and mortality10
was not affected by10
bp kenyon cells receive10
in the range of10
mechanism of action of10
of the r domain10
a pivotal role in10
a broad range of10
in adult cf patients10
glial fibrillary acidic protein10
of the gfp gene10
study was undertaken to9
aim of this work9
to be one of9
the results of this9
the characterization of the9
the stability of the9
to the pathogenesis of9
a total of patients9
is not required for9
such as multiple sclerosis9
we examined whether the9
fluorescence recovery after photobleaching9
could be related to9
in order to identify9
be explained by the9
university of north carolina9
studies have demonstrated that9
was not observed in9
that the level of9
is dependent on the9
of influenza a virus9
with hematoxylin and eosin9
the cells were washed9
may play an important9
japan we investigated the9
was shown to be9
examine the effects of9
a significant increase of9
in primary cultures of9
present results suggest that9
by cff and nih9
by grants from the9
were more likely to9
was cloned into the9
the percentage of gfp9
washed three times with9
in relation to the9
that are responsible for9
the cells were infected9
are not well understood9
in the auditory cortex9
play a critical role9
bovine respiratory disease complex9
by in situ hybridization9
it has been proposed9
no difference in the9
the concentration of the9
rna was extracted from9
we took advantage of9
revealed the presence of9
supported by cff and9
at the start of9
have been found in9
plasma membrane expression of9
of the number of9
the early stages of9
the dynamics of the9
in the cystic fibrosis9
a result of the9
to the end of9
case western reserve university9
and the presence of9
study was to examine9
in vivo and in9
supported by the cystic9
will allow us to9
were carried out in9
at the beginning and9
to be able to9
test was used to9
of the orf gene9
cf cells compared to9
the activities of the9
has been implicated in9
of the airway epithelium9
be related to the9
of green fluorescent protein9
in the endoplasmic reticulum9
supported by the nih9
for the presence of9
we also show that9
a useful tool for9
a significant difference in9
we hypothesized that the9
piglets in the tgev9
is caused by mutations9
cells were grown in9
at the molecular level9
is not involved in9
the piglets in the9
in response to the9
the study of the9
similar results were obtained9
angelica tenuissima nakai in9
total number of reads9
the granule cell layer9
neural stem progenitor cells9
of reactive oxygen species9
department of biophysics and9
determine the effect of9
of astrocytes in the9
of nsp and nsp9
at various time points9
the primary motor cortex9
plays a critical role9
that the activation of9
japan in order to9
cells were maintained in9
has been proposed that9
the goal of this9
the intensity of the9
are responsible for the9
national institutes of health9
that the presence of9
suggest that activation of9
were identified in the9
medical and dental university9
of cftr in the9
the presence and absence9
is responsible for the9
investigated the role of9
compared to wild type9
the interaction of the9
under the same conditions9
in order to examine9
with a decrease in9
ml or v v9
for h at uc9
in the hippocampus and9
the sox cut site9
for min at uc9
the presence of both9
the coding region of9
that can be used9
are thought to be9
to understand the role9
the development of novel9
the use of a9
between the two groups9
development of a new9
and found that the9
the cells were fixed9
presence and absence of9
there were no differences9
for h at c9
after spinal cord injury9
in the corpus callosum8
have been reported to8
these data demonstrate that8
the presence of different8
for the loss of8
cells of the central8
expressed in the brain8
the activation of the8
it is necessary to8
department of cell biology8
on the development of8
is mediated by the8
by an increase in8
functional magnetic resonance imaging8
rate of decline in8
to study the role8
kenyon cells receive in8
app swe ps de8
the existence of a8
the hypothesis that the8
to the identification of8
in the mammalian brain8
cells receive in the8
was significantly higher in8
in the nervous system8
we report that the8
inhibit the replication of8
our goal is to8
we set out to8
cells transfected with the8
as well as on8
stained with hematoxylin and8
we developed a new8
that project to the8
by means of a8
important roles in the8
the peripheral nervous system8
expression was observed in8
school of medical science8
the analysis of the8
in both cell types8
in the amount of8
and the role of8
prior to cell lysis8
is supported by the8
of excitatory and inhibitory8
the role of these8
analysis was performed using8
receive in the dorsal8
mortality in cystic fibrosis8
the number of cells8
the type i ifn8
we have developed an8
the mechanism of the8
elucidate the role of8
and an increase in8
involved in the control8
a confidence level of8
were added to the8
a marked increase in8
did not differ significantly8
significantly decreased in the8
the effect of a8
black flying fox and8
less is known about8
in the mouse brain8
with the formation of8
of our study was8
the ca region of8
to a better understanding8
new insights into the8
nsp and nsp are8
neurons in the substantia8
hyogo college of medicine8
this study aimed to8
the age of weeks8
preliminary results show that8
we previously showed that8
in a number of8
of hepatitis c virus8
the expression of a8
in order to elucidate8
to understand the mechanism8
vaccination with chadox mers8
we were unable to8
children with cf and8
from the cell surface8
based on these results8
the antiviral effect of8
the mrna entry channel8
beginning and end of8
of the dorsal accessory8
is associated with a8
a mean age of8
in the adult brain8
on the presence of8
in learning and memory8
of la and dha8
during the development of8
the hippocampal ca region8
flying fox and human8
using the r h8
these data are consistent8
was to determine the8
a broad spectrum of8
human immunodeficiency virus type8
were washed three times8
of the cftr gene8
hepatitis b surface antigen8
of the cystic fibrosis8
neurons that project to8
have been linked to8
to elucidate the role8
of spinal cord injury8
is not fully understood8
we propose that the8
to be required for8
as a model system8
as a marker for8
synaptic transmission in the8
of the viral genome8
the inhibitory effects of8
the level of the8
have been used for8
are expressed in the8
regions of the brain8
a function of temperature8
graduate school of frontier8
in the course of8
the medial prefrontal cortex8
are associated with the8
to changes in the8
was found in the8
studied the effect of8
been implicated in the8
is observed in the8
at the apical membrane8
the beginning and end8
a student t test8
the amount of the8
the cerebral cortex and8
cells compared to wt8
inhibited the replication of8
enhanced green fluorescent protein8
in rat hippocampal slices8
to test whether the8
of reads in the8
the treatment of cf8
the maintenance of the8
to determine the effect8
in the lungs of8
but little is known8
in comparison with the8
this work was to8
at the onset of8
pediatric and adult patients8
in cultured hippocampal neurons8
the present results suggest8
is associated with the8
an important role of8
cd hi cd b8
as part of the8
cells were washed with8
similar to that of8
of this work was8
by confocal laser scanning8
were washed with pbs8
was kindly provided by8
an animal model of8
the spinal cord and8
for h at room8
study the role of8
the effects of a8
a mutation in the8
in the control group8
h at room temperature8
number of reads in8
of the spinal cord8
of the mushroom body8
was similar to that8
the results of the8
in the current study8
a powerful tool for8
with the exception of8
patients were included in8
the airway epithelial cells8
used to study the8
to a final concentration8
of the nervous system8
modified vaccinia virus ankara8
levels of neutralizing antibodies8
recent studies have shown8
no significant differences in8
at the protein level8
when compared to the8
plays a central role8
as well as for8
forced expiratory volume in8
can be found in8
was reported to be8
for pediatric and adult8
we suggest that the8
and incubated for h8
a part of the8
in the prefrontal cortex8
we examined effects of8
we find that the8
the determination of the8
proteins bc and a7
incubated for h at7
of the same age7
the number of reads7
are one of the7
is considered to be7
the presence of an7
in vivo imaging of7
compared with those of7
with different concentrations of7
by western blot analysis7
for each of the7
were significantly decreased in7
the impact of the7
demonstrate for the first7
this work is to7
experiments were carried out7
our study was to7
tested the hypothesis that7
in xenopus laevis oocytes7
the neuroprotective effect of7
at the beginning of7
that some of the7
included in the study7
this study we investigated7
adult patients with cf7
that most of the7
the underlying molecular mechanisms7
in the progression of7
after the onset of7
has not yet been7
in the form of7
supported by nih and7
the vicinity of the7
the cellular and molecular7
were used to amplify7
been reported to be7
the underlying mechanism of7
japan we previously reported7
the nt surrounding the7
by the total number7
involved in regulation of7
our data indicate that7
the mechanical properties of7
study is to investigate7
cystic fibrosis foundation therapeutics7
in a wide range7
plays a major role7
and their role in7
the aim of our7
been shown that the7
lead to a better7
not appear to be7
in cf and non7
in response to various7
the fluorescence intensity of7
that angelica tenuissima nakai7
was seen in the7
in an in vitro7
study we investigated the7
have been reported in7
japan we have previously7
vivo and in vitro7
this suggests that the7
inoculum was replaced with7
adult central nervous system7
results of this study7
of microglia and astrocytes7
equine infectious anemia virus7
in cf patients is7
animal care and use7
significant changes in the7
in the apical membrane7
study was to identify7
subjects were required to7
in infants with cf7
we recently reported that7
by the interaction with7
reduced the number of7
we found a significant7
university of occupational and7
resulted in a significant7
well as the number7
was to determine if7
in the brains of7
of the role of7
a change in the7
which is involved in7
the soluble form of7
of the cut site7
in the modulation of7
the pari lc plus7
of bdnf in the7
induced during poliovirus infection7
shown in figure a7
by a combination of7
the hepatitis b virus7
a new class of7
investigate the effects of7
was expressed in the7
significantly increased in the7
were kindly provided by7
is caused by a7
induction of type i7
is to investigate the7
data indicate that the7
which may contribute to7
the substantia nigra pars7
in order to understand7
we have recently reported7
untreated and heat shocked7
order to understand the7
it has been demonstrated7
translocation to the nucleus7
occupational and environmental health7
were seen in the7
to infection by brsv7
the developing cerebral cortex7
the egfp reporter gene7
is possible that the7
involved in the development7
examined the role of7
were significantly higher in7
in the development and7
of the interaction between7
the cff patient registry7
were no differences in7
of the peripheral er7
the results indicate that7
to the accumulation of7
was performed in the7
for a total of7
the aqueous extract of7
in cells treated with7
animals that received a7
in different brain regions7
analysis showed that the7
of porcine epidemic diarrhea7
of the mature form7
in the developing brain7
herpes simplex virus type7
a potent inhibitor of7
study was designed to7
coomassie brilliant blue g7
be due to a7
and astrocytes in the7
the signal recognition particle7
in a significant increase7
the distribution of the7
cf is characterized by7
in a previous study7
kyoto institute of technology7
treatment of cystic fibrosis7
cells were obtained from7
bronchial epithelial cell line7
has been reported in7
the organization of the7
and function of the7
studies indicate that the7
mlt h n treated7
did not show the7
used as a control7
this study we have7
neurons and glial cells7
the surface of lipid7
fos expression in the7
of changes in the7
performed in the presence7
cells were fixed and7
were not significantly different7
and characterization of a7
the dorsal part of7
from the endoplasmic reticulum7
an in vitro model7
the fact that the7
innate immune response to7
cf mice compared to7
by mutations in the7
which is consistent with7
in any of the7
toyohashi university of technology7
we are interested in7
is characterized by an7
on the cell membrane7
can be explained by7
to the central nervous7
kyoto university graduate school7
dorsal part of the7
as the number of7
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in the united states7
lower than that of7
the collapse of the7
the area of the7
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not been reported in7
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progenitor cells in the7
infected with chikv ls7
h n treated mice7
cystic fibrosis related diabetes7
a mouse model of7
the plasma membrane and7
the cells were then7
the replication of ndv7
it is not known7
of microglia in the7
the kinetics of the7
supported in part by7
well tissue culture plates7
was to evaluate the7
in the adult rat7
in the ventricular zone7
the specificity of the7
used to amplify the7
to investigate the effects7
adults with cystic fibrosis7
it is suggested that7
the identity of the7
is related to the7
cells in the adult7
h k me levels7
has been demonstrated in7
were significantly reduced in7
the authors declare that7
were cloned into the7
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was significantly higher than7
was identified as a7
an important role for7
support the hypothesis that7
kindly provided by dr7
and quality of life7
has been suggested to7
analysis revealed that the7
claws formed by the7
electrical stimulation of the7
due to lack of7
coding region of cftr7
institutional animal care and7
of occupational and environmental7
to examine the effects7
through a series of7
the involvement of the7
cause of morbidity and7
we investigated the role7
to contribute to the7
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sox cut site in7
and the expression of7
did not show any7
of cd t cells7
a single dose of7
accumulate in the nucleolus7
the change in the7
examine the role of7
our results showed that7
has been associated with7
on the role of7
the sequence of the7
hospital for sick children7
are present in the7
the vast majority of7
was used to assess7
in the striatum of7
respiratory syndrome coronavirus c7
the majority of the7
the molecular layer of7
c bl mice were7
to further investigate the7
decrease in the number7
that the rate of7
a sustained increase in7
different from that of7
similar to that observed7
of the patients with7
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which has been shown7
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one of the three7
bovine respiratory syncytial virus7
in pbs for min7
induce the formation of7
have been associated with7
our aim is to7
did not observe a7
the majority of patients7
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compared to wt cells7
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the morphology of the7
cells in the presence7
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the present study examined6
these results imply that6
a major component of6
to the cell membrane6
focused our attention on6
the neurons in the6
the lungs of cf6
and the cells were6
these studies demonstrate that6
national institute of advanced6
analyses were performed using6
fusion of autophagosomes with6
the antiviral effects of6
could be used to6
has been attributed to6
determine the role of6
a green fluorescent protein6
layer of the dentate6
to further characterize the6
the mechanism of action6
part of the spvi6
expression of cftr in6
the institutional animal care6
be a useful tool6
its mechanism of action6
by the formation of6
the development of new6
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and migrate to the6
we are grateful to6
a total volume of6
to address this question6
proteins as well as6
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was involved in the6
reverse genetics system for6
in c bl mice6
on the type of6
for h and then6
the induction of autophagy6
for a variety of6
flying fox cell lines6
we also examined the6
if there is a6
divided into three groups6
indicate that there are6
of the virus and6
highly expressed in astrocytes6
levels were measured by6
in the absence or6
in u os cells6
in animals vaccinated with6
in the gene encoding6
was inserted into the6
structure and function of6
to elucidate the mechanisms6
we have analyzed the6
kida department of bioscience6
was supported by a6
than in the control6
we examined the role6
discuss the role of6
and h k me6
at uc for min6
by a variety of6
quality of life in6
the sod g a6
the authors declare no6
expression of irf in6
and a bp kenyon6
differentiated airway epithelial cells6
was a significant difference6
the active site of6
we concluded that the6
care and use committee6
by the number of6
in our cf center6
transfected with the empty6
we hypothesized that these6
increased the frequency of6
we found that these6
explore the role of6
a significant number of6
in the somatosensory cortex6
the time of the6
both sides of the6
may serve as a6
which is characterized by6
single dose of chadox6
japan we have reported6
not only in the6
ffm and fat mass6
was significantly reduced in6
and the change in6
pivotal role in the6
school of medical sciences6
that neutrophils and inflammatory6
we found that in6
satoshi kida department of6
were collected from the6
school of frontier biosciences6
for the purpose of6
porcine reproductive and respiratory6
microscopy was used to6
at room temperature and6
and then infected with6
muc and muc ac6
in the frontal cortex6
for the expression of6
the gfp substrate and6
the expression patterns of6
cf lung disease severity6
significant differences in the6
is expected to be6
cells were incubated for6
results indicated that the6
the calyx of held6
part of the left6
be used to study6
data will be presented6
used a combination of6
fluorescence lifetime imaging microscopy6
ca region of the6
has the potential to6
this work is supported6
the existence of the6
pyramidal neurons in the6
and its role in6
detected as early as6
a human neuroblastoma cell6
evaluated the effects of6
is not clear whether6
that they have no6
titers were determined by6
in the white matter6
a rat model of6
the efficiency of the6
this study aims to6
these two types of6
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purification of recombinant proteins6
which is known to6
with mild to moderate6
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is to understand the6
on the analysis of6
of h ak ub6
compared to wt mice6
and mortality in cystic6
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adult neural stem cells6
of live cell imaging6
hsod g a mice6
we investigated the expression6
industrial science and technology6
for the induction of6
and the extent of6
declare that they have6
from the middle east6
applied to the apical6
of vitamin d deficiency6
mice as compared to6
viral and host factors6
with angelica tenuissima nakai6
of the host cell6
in response to a6
of newcastle disease virus6
in a model of6
dose of chadox mers6
of adults with cf6
glial cells and neurons6
for the characterization of6
have been implicated in6
caused a decrease in6
we used a novel6
supported by cystic fibrosis6
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the nature of the6
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role of cftr in6
was significantly lower than6
be expressed in the6
shown to be involved6
have been identified in6
japan the present study6
by nih and cff6
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to the existence of6
from the viral genome6
percentage of infected cells6
to act as a6
significantly lower than that6
the bovine respiratory disease6
in the adult mouse6
were fixed with paraformaldehyde6
it was observed that6
mechanical properties of the6
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the role of this6
difference between groups compared6
patients followed at the6
department of chemistry and6
a soluble form of6
of the most common6
we observed a strong6
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for their ability to6
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indicates a significant difference6
for a pulmonary exacerbation6
cre c ebpb fl6
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to determine the role6
have the potential to6
confocal laser scanning microscope6
in order to address6
as a model of6
organic and biomolecular chemistry6
the core of the6
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suggesting a role for6
neurons projecting to the6
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the most common mutation6
been found to be6
by incubating the cells6
plays an essential role6
the different cell types6
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increased morbidity and mortality6
institute of science and6
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institute of advanced industrial6
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were used as controls6
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significantly higher in the6
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proteins in the nucleolus6
have been developed for6
in the developing cerebral6
information processing in the6
leads to a significant6
have not yet been6
times with pbs and6
the role of cftr6
cells in the cns6
region of the hippocampus6
collapse of the peripheral6
the expression of p6
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the results indicated that6
a fraction of the6
on the effect of6
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was larger in the6
graduate school of arts6
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hi cd b f6
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results suggest that these6
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we examined the expression6
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nuclear translocation of the6
in subjects with cf6
will be discussed in6
connect to the a6
investigate the influence of6
known to be a6
understand the mechanism of6
of type i interferon6
a selective inhibitor of6
at a dose of6
the mean number of6
sputum samples were collected6
in most of the6
human neuroblastoma cell line6
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there is evidence that6
a function of the6
the induction of the6
the cleaved elp tag6
reproductive and respiratory syndrome6
type i ifn signaling6
can be applied to6
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studied the interaction of6
in the granule cell6
hek t and hela6
respiratory syncytial virus infection6
in addition to their6
cells were washed twice6
that nsp and nsp6
the therapeutic potential of6
electrophoretic mobility shift assay6
the cl pro moiety6
an increase of the6
university of health and6
at a dilution of6
number of cells expressing6
in the molecular layer6
is a hallmark of6
collapsin response mediator protein6
were prepared from the6
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changes in the expression6
the first step of6
pcr and western blot6
to the lack of6
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could be found in6
cells were pretreated with6
leads to the formation6
at the site of6
the number of gfp6
mrna and protein expression6
to be crucial for6
suggesting the importance of6
between groups compared by6
shimojo implicit brain function6
is located in the6
inhibition of autophagic flux6
increasing evidence suggests that6
may be associated with6
for the production of6
difference was observed in6
shown to play an6
into the dorsal accessory6
cerebral cortex and hippocampus6
has no effect on6
in the design of6
infection of target cells6
structure and dynamics of6
a transgenic mouse model6
at later time points6
in the brain is6
the national institutes of6
both nsp and nsp6
were divided into two6
g for min at6
no significant differences were6
in astrocytes and microglia6
for peer review of6
findings indicate that the6
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may be responsible for6
the important role of6
osaka university graduate school6
in mouse models of6
regulate the expression of6
these results provide a6
inflammatory monocytes in the6
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in lung tissue of6
was performed to determine6
changes in gene expression6
treatment of sputum with6
the blood brain barrier6
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ng cells in the6
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the transfection efficiency of6
the increase of the6
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examined the expression of6
significant difference between groups6
in the induction of6
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the frequency of the6
soluble form of the6
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the modulation of the6
and distribution of the6
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by the lack of6
was not associated with6
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cell infiltration into the6
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tested the effects of6
total rna was extracted6
washed with pbs and6
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the replication of rna6
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aim of our study6
was to examine the6
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by the activation of6
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found that the number6
the components of the6
a high degree of6
department of integrative physiology6
caucasian cf patients who6
we report here the6
neurons in the rat6
over the past years6
poliovirus proteins bc and6
and molecular dynamics simulations6
comparable to that of6
the contribution of the6
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japan to investigate the6
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the spinal gray matter6
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advanced industrial science and6
different from those of6
school of arts and6
the peripheral er network6
cell proliferation in the6
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our findings indicate that6
authors declare that they6
bovine lung extract surfactant6
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neuroscience and brain technologies5
over the study period5
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the consensus sequence of5
detailed characterization of the5
essential role in the5
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total of patients were5
a powerful tool to5
ampa and nmda receptors5
the formation of an5
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differences in the expression5
role in the development5
supported by cfft and5
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also significantly reduced in5
experiments showed that the5
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gfp substrate and the5
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information science and technology5
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the beneficial effects of5
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the amount of gfp5
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the most commonly used5
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role of astrocytes in5
the present work we5
cells were fixed with5
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by confocal fluorescence microscopy5
they have no competing5
in line with our5
stem progenitor cells in5
the localization of gfp5
in both black flying5
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the number of c5
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panels present typical results5
the dependence of the5
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we previously demonstrated that5
of the mechanism of5
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efficacy and safety of5
and hela cells were5
is a useful tool5
further our understanding of5
be influenced by the5
investigated the expression of5
may represent a promising5
cells in the hippocampus5
increase in ca i5
the number of the5
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to investigate the mechanisms5
fold serial dilutions of5
expression in the adult5
have focused on the5
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one of the key5
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in the activation of5
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significant difference between the5
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percentage of gfp positive5
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due to the presence5
the potential role of5
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the context of the5
this study demonstrates that5
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factor x and x5
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study the effects of5
oral glucose tolerance test5
molecular mechanisms underlying the5
as described in the5
cftr at the cell5
mammalian target of rapamycin5
will be used to5
total vitamin d intake5
transcranial flavoprotein fluorescence imaging5
the anterior cingulate cortex5
infection of the brain5
are derived from the5
using an antibody directed5
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it is essential to5
by means of the5
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small heat shock protein5
with cf and their5
these results demonstrate the5
cells infected with chikv5
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were performed in the5
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is highly expressed in5
total of cf patients5
were infected with rsv5
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found at the beginning5
a new method for5
we would like to5
the current study we5
does not affect the5
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course of the disease5
the protective effect of5
the nucleolus upon hs5
van den boom et5
can be modulated by5
a significant impact on5
did not correlate with5
of the innate immune5
the neuronal activity of5
inflammatory response in cf5
within the central nervous5
to understand the molecular5
funders had no role5
has been linked to5
recent studies have demonstrated5
to be a useful5
in good agreement with5
was calculated from the5
caused a significant increase5
our preliminary results show5
a mouse model for5
whole cell patch clamp5
terminal domain of spike5
apical surface of the5
significant effect on the5
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analyzed by confocal microscopy5
cftr in the presence5
was replaced with medium5
h k me and5
cells were fixed in5
taking advantage of the5
t cells were transfected5
was predicted to be5
porcine hemagglutinating encephalomyelitis virus5
dmem supplemented with fbs5
by western blot using5
we have established a5
a large fraction of5
we have generated a5
has yet to be5
of the functions of5
is found to be5
during the period of5
cxrs and chest cts5
significantly lower in the5
we did not find5
to further understand the5
enriched in the nucleolus5
of the autophagy pathway5
to the regulation of5
which leads to the5
was used as an5
we investigated effects of5
may be explained by5
may be a promising5
in heat shocked cells5
the surface expression of5
scale bar represents mm5
is to develop a5
to a decrease in5
h ak ub recovery5
department of applied biology5
the regulation of inflammation5
for h in the5
assess the impact of5
may account for the5
we also investigated the5
the adult central nervous5
are shown in fig5
be considered as a5
forms of synaptic plasticity5
the changes in the5
in the peripheral nervous5
based on these findings5
human respiratory syncytial virus5
of molecular biology and5
a deeper understanding of5
levels of lc b5
institute for biophysical chemistry5
from animals vaccinated with5
induced changes to the5
viruses in vitro and5
by a factor of5
sputum of cf patients5
of the viral life5
did not significantly affect5
no significant changes in5
t cells were transiently5
compared to control subjects5
compared to the wt5
group than in the5
the role of rab5
of cd and cd5
in order to gain5
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this study suggests that5
also show that the5
in order to obtain5
the herpes simplex virus5
nsp binds to the5
the structure and dynamics5
can be related to5
the absence of the5
we observed a significant5
proteins nsp and nsp5
at days of age5
was compared to the5
astrocytes and microglia in5
expressing cells in the5
aid for jsps fellows5
proteins involved in the5
added to each well5
the open reading frame5
only in the presence5
er ca store expansion5
the presence of nsp5
type i ifns and5
slovak academy of sciences5
these results demonstrated that5
admission and discharge pfts5
type i and type5
been shown to have5
with excitation and emission5
well as on the5
were significantly increased in5
coronavirus infectious bronchitis virus5
of the basal ganglia5
different parts of the5
as described previously and5
on the level of5
the absence or presence5
is very similar to5
the pari eflow rapid5
at different stages of5
to play a key5
progression of the disease5
rna and dna viruses5
of the amino acids5
the mechanism underlying the5
brain and spinal cord5
was carried out on5
showed an increase of5
of the activity of5
has been used as5
scanning window of nt5
and transferred to uc5
sensitive short circuit current5
a region of the5
chimera with protein tag5
of the study was5
of patients in the5
mechanism by which the5
mrna was expressed in5
it is shown that5
dependent protein kinase ii5
were measured by a5
swe ps de mice5
was used to remove5
of information science and5
are the first to5
incubated at uc for5
of the free energy5
of the hepatitis b5
and is associated with5
of middle east respiratory5
in the field of5
the spatial distribution of5
to investigate the influence5
here we investigated whether5
the regulation of enac5
incubating the cells with5
a model in which5
to the number of5
lung function in cf5
of cell adhesion molecules5
the age of the5
was performed using a5
than that of the5
investigate the ability of5
as well as by5
replication of rna viruses5
cells for h at5
phase ii clinical trials5
in comparison to the5
young adults with cf5
rats were divided into5
of glial cells in5
has not been elucidated5
the inflammatory response in5
have a role in5
it has been known5
of the sequences of5
and the development of5
physical properties of the5
of decline in lung5
is the presence of5
to understand the mechanisms5
activity is regulated by5
to the generation of5
a scanning window of5
as shown in the5
in the cerebellum of5
is due to the5
increased sult e activity5
granule cells in the5
dispersal of the golgi5
no significant change in5
an antibody directed against5
protein and mrna levels5
institute of molecular biology5
in both cell lines5
it is unclear whether5
examined the influence of5
in the first year5
the complexity of the5
use of laboratory animals5
the cells transfected with5
will be required to5
school of life sciences5
major role in the5
a marked decrease in5
was removed and the5
graduate school of engineering5
the first time the5
in cf cells compared5
the mode of action5
in the posterior lateral5
between the ages of5
more than half of5
these results suggest a5
in the supernatant of5
mediated antiviral activities of5
the idea that the5
of arts and sciences5
for min on ice5
the identification of the5
the first time that5
targeted production of il5
we recorded neuronal activity5
molecular layer of the5
suggesting the existence of5
led to an increase5
the end of p5
the plasma membrane expression5
in the establishment of5
compared with the control5
the lifetime of the5
terminal domain of the5
study was to assess5
phosphorylation of the r5
as a potential therapeutic5
compared to those of5
the hippocampal dentate gyrus5
is thought to play5
it remains to be5
homozygous f del mice5
also found in the5
we have constructed a5
study was supported by5
did not bind to5
oxidative stress induced by5
of the reporter gene5
results indicate that there5
after adjusting for age5
in close proximity to5
a novel role for5
and use of laboratory5
on the size of5
in the anterior pituitary5
results demonstrate that the5
expression and activity of5
used to identify the5
our understanding of the5
to our understanding of5
the middle of the5
it is expected that5
is believed to be5
with dnas coding for5
in the ratio of5
both black flying fox5
in order to explore5
cells were seeded on5
we generated transgenic mice5
part of the lv5
compared with the mock5
with the plasma membrane5
is a powerful tool5
pcg proteins to the5
was also found to5
with the help of5
the number of fluorescent5
susceptible to infection by5
and the level of5
and at the end5
toward the gfp substrate5
the interactions between the5
disease is characterized by5
in male and female5
more than of the5
no significant differences between5
in human airway epithelia5
by standard plaque assay5
the reporter gene expression5
the expression of several5
we show here that5
crystal structure of the5
not involved in the5
the secondary structure of5
for the analysis of5
we demonstrated that the5
we have identified the5
to the wild type5
of f del cftr5
associated with an increase5
flying fox cells was5
based on the analysis5
roles in the development5
various time points post5
at each time point5
was to study the5
to the onset of5
the severe acute respiratory5
was further confirmed by5
on the kinetics of5
to a number of5
the release of the5
in rat visual cortex5
define the role of5
the insertion of a5
at all time points5
that nsp binds to5
cells were washed three5
cells stably transfected with5
the induction of type5
of the lipid bilayer5
the fusion of autophagosomes5
and expressed as log5
of the viral proteins5
involved in this process5
of airway epithelial cells5
reported in the literature5
the construction of a5
is in agreement with5
in the production of5
we show that a5
of type i ifns5
cftr chloride channel activity5
airway epithelial cells in5
with serial dilutions of5
been proposed to be5
on the aggregation of5
in adults with cf5
the cells were incubated5
order to elucidate the5
and neural stem cells5
is widely used to5
was absent in the5
has emerged as a5
of cf patients in5
result suggests that the5
role of microglia in5
in the cns and5
probably due to the5
or in combination with5
expression and function of5
and black flying fox5
the ca i response5
we previously found that5
patients and healthy controls5
the direction of the5
in situ hybridization analysis5
provide new insights into5
the f del mutation5
has been studied by5
was observed between the5
alpn and a bp5
the center of the5
was mutated to a5
of biophysics and life5
lungs of cf patients5
similar to those of5
of dopaminergic neurons in5
as a receptor for5
it is difficult to5
approved by the institutional5
and s b fig5
the absence of trypsin5
ccl and cx cl5
from p to p5
ipsilateral hand and foot5
an extension of the5
as a starting point5
in glial cells and5
has been known that5
we studied the effect5
the primary auditory cortex5
carolina at chapel hill5
expressed in t cells5
male and female mice5
may be useful for5
work is supported by5
these results support the5
the increase in the5
were isolated from the5
project to the dorsal5
had no role in5
decline in pulmonary function5
the claws formed by5
excitatory and inhibitory inputs5
sites a and b5
one located in the5
cut site in limd5
the enteric tropism determinant5
population of inflammatory monocytes5
studies have suggested that5
the gfp gene was5
might be due to5
african green monkey kidney5
infected with pseudomonas aeruginosa5
activities of angelica tenuissima5
os cells transfected with5
was carried out to5
pellets were resuspended in5
of the respiratory tract5
used in combination with5
pulsed field gel electrophoresis5
has not been reported5
role of rab in5
play a central role5
the morris water maze5
care and use of5
in children with cystic5
has been identified as5
den boom et al5
have no competing interests5
the pathogenesis of cf5
at the bottom of5
in the hippocampal neurons5
of a mixture of5
findings of this study5
of airway surface liquid5
in the previous study5
japan in this study5
cells were stimulated with5
we have been using5
gaba a receptors in5
of gfp positive cells5
been shown to increase5
role in this process5
cf patients compared to5
in the hippocampal dentate5
was significantly lower in5
order to determine the5
used to measure the5
of the growth cone5
recently reported that the5
is likely that the5
role in the pathogenesis5
angelica tenuissima nakai and5
the induction of ltp5
to be a powerful5
was found at the5
of the cl pro5
evaluate the efficacy of5
bridge the gap between5
cells transiently transfected with5
to assess whether the5
was to identify the5
gene expression in astrocytes5
of the coding region5
of the cf patients5
total rna was isolated5
a duplicated subgenomic promoter5
the interaction between the5
between alpn and a5
video s and figure5
progression of lung disease5
mice were treated with5
the translocation of the5
angelica tenuissima nakai can5
the gene modifier study5
formed by the a5
caused a significant decrease5
the result suggests that5
thought to play a5
rats were exposed to5
the sequence of s5
in the cf airway5
of patients with cf5
significantly reduced in the5
of lipid droplets in5
of the a bp5
the type i interferon5
large number of neurons5
be used to monitor5
gunma university graduate school5
of mental disorder research5
and differential scanning calorimetry5
the funders had no5
changes in expression of5
the data suggest that5
expression and purification of5
and incubated at uc5
katsuei shibuki department of5
for the role of5
from the posterior lateral5
critical role in the5
in view of the5
the functionality of the5
we have been able5
means and sem of5
the ratio of the5
significantly different from that5
in the nucleus of5
have not been well5
time course of the5
institute of physical chemistry5
here we demonstrate that5
compared to the wild5
the proportion of patients5
been previously shown to5
of the gfp substrate5
study was to compare5
by angelica tenuissima nakai5
antiviral activities of angelica5
the findings suggest that5
a kind gift from5
for the maintenance of5
ministry of science and5
the rna binding motifs5
be used to determine5
hela cells were pretreated5
as well as from5
would be expected to5
performed in order to5
was significantly inhibited by5
mutations in the gene5
a key regulator of5
which is responsible for5
at the cellular level5
cells were inoculated with5
the functional properties of5
may be used to5
with the aim of5
were expressed in the5
to the level of5
to be important for5
cells in the brain5
some of them are5
higher ionizing radiation exposure5
vector was used as5
an increased number of5
used as a model5
in the adult cf5
the mean age of5
the molecular basis for5
in the study of5
in cells transfected with5
our results indicated that5
in this type of5
the second cleavage site5
has not been fully5
pathogenesis of cf lung5
we have begun to5
in part by the5
cells were incubated at5
be responsible for the5
balb c mice were5
we studied the interaction5
the number of astrocytes5
with the increase of5
the elp tag from5
in the table below5
compared with the untreated5
with fetal calf serum5
of gstt and gstm5
of anatomy and neurobiology5
confirmed the presence of5
play a pivotal role5
would result in the5
based on the results5
we have also shown5
time points post infection5
the correlation between the5
analyzed the effect of5
correlated with changes in5
by the administration of5
was measured using the5
induced nucleolar accumulation of5
we report here that5
compared to the only5
in order to investigate5
to suppress global mrna5
of amino acid residues5
inhibition of virus replication5
the gene expression profile5
black flying fox brain5
of pulmonary exacerbations in5
supernatants were collected and5
in terms of the5
leading cause of morbidity5
recent studies suggest that5
study the effect of5
aid for young scientists5
after the addition of5
studies have been conducted5
was then used to5
which are known to5
were incubated with the5
led to the development5
nsp and nsp bind5
added to the cells5
to the effect of4
of the f protein4
the subcellular localization of4
we could not detect4
as the sum of4
with sd is shown4
expression in plant cells4
peripheral blood mononuclear cells4
and molecular mechanisms that4
this research was supported4
in plant cells by4
may be important for4