bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
ang ii	548
angiotensin ii	451
converting enzyme	439
angiotensin system	263
blood pressure	161
acute respiratory	132
ace inhibitors	107
smooth muscle	95
type receptor	95
lung injury	93
ii type	92
ang i	92
angiotensin converting	91
respiratory syndrome	89
severe acute	86
ii receptor	85
growth factor	84
cardiovascular disease	83
heart failure	80
receptor blockers	78
coronavirus disease	75
amino acid	74
oxidative stress	73
ace expression	72
mas receptor	68
angiotensin receptor	68
angiotensin i	63
ace activity	62
epithelial cells	62
brain ras	61
novel coronavirus	61
spike protein	60
severe critical	57
diabetic nephropathy	56
protein kinase	55
gut microbiota	55
podocyte injury	55
ace gene	54
plasma membrane	53
acei arb	52
vascular smooth	52
endothelial cells	52
renin receptor	52
ras inhibitors	51
respiratory distress	50
muscle cells	49
amino acids	48
enzyme inhibitors	48
distress syndrome	47
ace ang	46
angiotensinconverting enzyme	44
renin angiotensin	44
myocardial infarction	43
syndrome coronavirus	42
diabetes mellitus	42
gene expression	42
sars coronavirus	42
animal models	42
endothelial dysfunction	41
nitric oxide	39
high glucose	39
kidney disease	38
aldosterone system	38
ang iii	37
local ras	37
ace inhibitor	37
aceis arbs	36
lung cancer	36
human ace	36
neutral endopeptidase	36
type diabetes	35
hypertensive rats	35
vascular endothelial	35
deficient mice	35
hypertensive patients	34
ace deficiency	34
ras activation	33
cord uid	33
doc id	33
nervous system	32
signal transduction	32
angiotensin type	32
adipose tissue	31
receptor antagonist	31
classical ras	31
activated protein	31
blood flow	30
host cells	30
ang iv	30
important role	30
ace receptor	30
oxygen species	30
reactive oxygen	30
acute lung	30
mrna expression	30
severe covid	30
bone marrow	29
protein expression	29
clinical trials	29
ace ace	29
transgenic mice	29
spontaneously hypertensive	28
ras proteins	28
ras components	28
renal injury	28
clinical characteristics	28
may also	27
mas axis	27
induced lung	27
tissue ras	27
fusion proteins	26
transmembrane domain	26
cytokine storm	26
lung tissue	26
risk factors	26
kidney injury	26
central nervous	25
inflammatory cytokines	25
ras blockade	25
disease severity	25
necrosis factor	25
map kinase	25
ace shedding	25
senescent cells	25
endoplasmic reticulum	24
system inhibitors	24
cell growth	24
systematic review	24
er stress	24
renin activity	23
ras wt	23
signaling pathway	23
cardiovascular diseases	23
ras system	23
ii levels	23
transforming growth	23
lung tumor	23
cell death	23
reninangiotensin system	23
infected patients	23
factor receptor	22
cell entry	22
crucial role	22
viral entry	22
recombinant human	22
signaling pathways	22
receptor blockade	22
ace levels	22
critical outcomes	22
ace axis	22
arb users	22
clinical outcomes	22
increased ace	22
trabecular bone	22
cardiac hypertrophy	22
active site	22
enzyme inhibitor	21
tumor cells	21
receptor blocker	21
ras pathway	21
functional receptor	21
molecular mechanisms	21
viral infection	21
increased risk	21
immune responses	21
coronavirus infection	21
ace protein	21
tumor necrosis	21
insulin resistance	21
gastrointestinal tract	21
beneficial effects	20
epidermal growth	20
circulating ras	20
hepatic fibrosis	20
diabetic rats	20
host cell	20
prorenin receptor	20
binding domain	20
intensive care	20
ace mrna	20
cell proliferation	20
virus infection	20
orx mice	20
cohort study	19
liver disease	19
ii receptors	19
pulmonary hypertension	19
liver fibrosis	19
receptor mas	19
united states	19
severe disease	19
tumor cell	19
protective effects	19
therapeutic target	19
renal disease	19
left ventricular	18
protective role	18
provided adjusted	18
blood vessels	18
immune system	18
tumor tissue	18
significantly reduced	18
portal pressure	18
cardiovascular system	18
immune response	18
cellular senescence	18
enzyme inhibition	18
cleavage site	17
coupled receptor	17
vsmc senescence	17
basement membrane	17
higher levels	17
type i	17
patients infected	17
receptor axis	17
human coronavirus	17
collecting duct	17
ras blockers	17
chronic kidney	17
tissue injury	17
angiotensin receptors	17
clinical studies	17
alveolar epithelial	17
ace inhibition	17
podocyte apoptosis	17
vascular senescence	17
novel therapeutic	16
control group	16
critical illness	16
integral membrane	16
early dn	16
increased expression	16
mouse model	16
cardiac dysfunction	16
normal lung	16
also known	16
receptor signaling	16
renal function	16
knockout mice	16
fatty acids	16
proteolytic cleavage	16
among patients	16
rat model	16
endothelial growth	15
dm group	15
sex differences	15
membrane protein	15
portal hypertension	15
gene polymorphisms	15
gender differences	15
rat brain	15
developing severe	15
acute kidney	15
coronavirus spike	15
inflammatory response	15
essential hypertension	15
ectodomain shedding	15
protective effect	15
glomerular filtration	15
serum potassium	15
senescence via	15
potential therapeutic	15
cell types	15
diabetic patients	15
three groups	15
innate immune	15
extracellular matrix	15
induced senescence	15
respiratory tract	14
receptor ace	14
membrane fusion	14
receptor gene	14
diabetic mice	14
may contribute	14
ii production	14
angiotensin iv	14
human angiotensin	14
lipid accumulation	14
ras activity	14
neurogenic hypertension	14
hospitalized patients	14
nadph oxidase	14
animal model	14
renin inhibitors	14
kinin system	14
nuclear factor	14
proinflammatory cytokines	14
heart function	14
organ damage	14
highly expressed	14
plasma renin	14
expressing cells	14
insulin receptor	14
may lead	14
lipid metabolism	14
mas receptors	14
pressure regulation	14
retrospective cohort	14
ace angiotensin	14
experimental models	14
clinical course	14
ii induces	14
binding protein	13
critical role	13
pulmonary fibrosis	13
ras genes	13
viral infections	13
angiotensin iii	13
related carboxypeptidase	13
cardiac myocytes	13
endothelial cell	13
local tissue	13
significant association	13
muscle cell	13
reticulum stress	13
dm ab	13
case series	13
cancer cells	13
alveolar cells	13
cancer risk	13
central role	13
extracellular signal	13
cell surface	13
enzyme activity	13
adjusted estimates	13
spike glycoprotein	13
renin inhibitor	13
human podocytes	13
podocyte loss	13
tyrosine kinases	13
critical disease	13
masr axis	13
induced diabetic	13
lung fibrosis	13
receptor antagonists	13
animal studies	12
protective arm	12
mitochondrial dysfunction	12
cov infection	12
filtration barrier	12
brain renin	12
viral rna	12
therapeutic targets	12
regulated kinase	12
significantly increased	12
mitochondrial fission	12
statistically significant	12
enzyme gene	12
angiotensin peptides	12
ab group	12
high blood	12
lung disease	12
virus entry	12
coronary artery	12
cell membrane	12
receptor binding	12
pathological conditions	12
viral particles	12
clinical implications	12
lower risk	12
pulmonary vascular	12
receptor tyrosine	12
podocyte damage	12
type diabetic	12
key role	12
induced podocyte	12
subgroup analysis	12
intrarenal ras	12
high dose	12
viral replication	11
type ii	11
gtpase activity	11
pathological changes	11
like receptor	11
foot processes	11
vascular permeability	11
neutral amino	11
direct renin	11
plasma levels	11
converts angiotensin	11
activated ras	11
plasma acetate	11
may play	11
biologically active	11
significant difference	11
human renin	11
recombinant ace	11
ras imbalance	11
lung function	11
mice lacking	11
system blockers	11
glomerular basement	11
east respiratory	11
cardiac fibrosis	11
detrimental effects	11
sars virus	11
multiple comparisons	11
cardiovascular risk	11
ace may	11
enzyme angiotensin	11
arterial hypertension	11
disease progression	11
mortality estimates	11
clinical data	11
actin cytoskeleton	11
negative regulator	11
systemic inflammation	11
glomerular podocytes	11
heart disease	11
receptor subtypes	11
cardiac fibroblasts	11
ras may	11
produce ang	11
exposure time	11
endothelial function	11
active sites	11
nep may	11
high risk	11
previous studies	11
induced cardiac	11
spike proteins	11
soluble ace	11
small intestine	11
renal angiotensin	10
yeast two	10
several studies	10
ras systems	10
structural basis	10
immune complexes	10
transduction pathways	10
type alveolar	10
oxide synthase	10
mesangial cells	10
subfornical organ	10
immune cells	10
side effects	10
brush border	10
diabetic renal	10
gut dysbiosis	10
injury angiotensin	10
therapeutic potential	10
ii formation	10
rats angiotensin	10
control study	10
inflammatory responses	10
mortality rates	10
inflammatory effects	10
cardiac remodeling	10
positive patients	10
foot process	10
acid transporter	10
functional expression	10
signaling mechanisms	10
receptor stimulation	10
expression levels	10
dependent manner	10
associated protein	10
ii infusion	10
assisted surgery	10
clinical features	10
pulmonary disease	10
mast cell	10
diabetic kidney	10
robotic assisted	10
segmental glomerulosclerosis	10
serine threonine	10
pulmonary vasoconstriction	10
physiological functions	10
protein levels	10
one study	10
transforming activity	10
mucociliary clearance	10
may increase	10
electron microscopy	10
transgenic rats	10
significantly higher	10
essential role	10
artery disease	10
middle east	10
receptor subtype	9
long term	9
catalytic activity	9
acid residues	9
cytokine production	9
creative commons	9
induced vsmc	9
decreased expression	9
inflammatory cells	9
renal fibrosis	9
binding sites	9
critically ill	9
taken together	9
patients may	9
ejection fraction	9
previous sars	9
testosterone deficiency	9
glycogen synthase	9
mortality rate	9
glomus cells	9
glucose uptake	9
proximal tubule	9
lower odds	9
clinical trial	9
tyrosine kinase	9
higher crude	9
protein interactions	9
ras dysregulation	9
studies using	9
egf receptor	9
cardiovascular complications	9
human homolog	9
ras overactivation	9
mortality among	9
human lung	9
recent studies	9
pulmonary ras	9
salt hypertension	9
mg ml	9
cell signaling	9
diabetic complications	9
cardiac angiotensin	9
vascular inflammation	9
bound ace	9
renin receptors	9
essential regulator	9
spike receptor	9
ace expressing	9
podocyte hypertrophy	9
local renin	9
receptor type	9
cell biology	9
db mice	9
resistant hypertension	9
recent study	9
induced hypertension	9
lung ventilation	9
lung failure	9
renin prorenin	9
increased plasma	9
induced vascular	9
insulin sensitivity	9
skeletal muscle	9
ii generation	9
cardiac injury	9
system blockade	9
angiotensin peptide	9
human vascular	9
focal segmental	9
null mice	9
pulmonary blood	9
ras inhibition	9
epicardial adipose	9
risk factor	8
original studies	8
lung damage	8
ii stimulates	8
china clinical	8
podocyte detachment	8
previously described	8
glucose transporter	8
cells within	8
also found	8
inflammatory cytokine	8
clinical relevance	8
general population	8
transcription factors	8
cell rna	8
pivotal role	8
systemic ras	8
insertion deletion	8
ace imbalance	8
well established	8
tissue ace	8
secretory phenotype	8
plasminogen activator	8
new therapeutic	8
corona virus	8
mrna levels	8
linked genes	8
new coronavirus	8
human heart	8
glomerular diseases	8
palmitic acid	8
mesenchymal transition	8
akita mice	8
genes involved	8
length human	8
cancer patients	8
hypertensive rat	8
high levels	8
hypoxic pulmonary	8
myocardial fibrosis	8
cell senescence	8
orx group	8
mice angiotensin	8
cell body	8
cells via	8
pooled analysis	8
novel angiotensin	8
increased ang	8
tissue distribution	8
breast cancer	8
serum angiotensin	8
apical membrane	8
metabolic syndrome	8
gene deletion	8
cell apoptosis	8
reduced ace	8
generating ang	8
adult inpatients	8
nep expression	8
db db	8
sympathetic nervous	8
sodium delivery	8
saccharomyces cerevisiae	8
ras plays	8
juxtaglomerular cells	8
pressure elevation	8
circulating ang	8
antibiotic intervention	8
mechanical stress	8
outcomes among	8
binding site	8
mediated virus	8
dependent pathways	8
adrenal gland	8
observational studies	8
ras signaling	8
receptor activation	8
ras derivatives	8
induced acute	8
serum ace	8
coronavirus nl	8
virus replication	8
activity may	8
tumor growth	8
patients taking	8
tissue damage	8
performed using	8
high level	8
antihypertensive drugs	8
aortic aneurysm	8
intrarenal renin	8
beneficial effect	8
podocyte injuries	8
lung epithelial	8
yeast strains	8
natriuretic peptide	8
serine proteases	8
second messenger	8
renal ace	8
bone metabolism	8
serine protease	8
circulating renin	8
increasing ace	8
care units	8
potential role	8
pulmonary arterial	8
cell lung	8
two groups	8
coronavirus pneumonia	8
intracellular ang	8
renal hypertrophy	7
connective tissue	7
significant differences	7
vascular remodeling	7
low dose	7
receptor expression	7
viral spike	7
enzyme protects	7
fatty acid	7
diabetic retinopathy	7
might lead	7
previously reported	7
kinase inhibitor	7
transmembrane serine	7
respiratory diseases	7
density lipoprotein	7
higher expression	7
entry receptor	7
glomerular sclerosis	7
abdominal aortic	7
glomerular podocyte	7
mechanical ventilation	7
type mice	7
genetic ace	7
rat liver	7
receptors mediate	7
linked mental	7
supplementary table	7
inhibitory activity	7
insensitive carboxypeptidase	7
may provide	7
kinase kinase	7
sars patients	7
bone mineral	7
ace balance	7
myocardial ace	7
sars pathogenesis	7
brain angiotensin	7
induce podocyte	7
angiotensin systems	7
membranous nephropathy	7
hospital mortality	7
patients hospitalized	7
mineral density	7
ace activities	7
including hypertension	7
targeted derivatives	7
acid linker	7
adverse effects	7
ace function	7
bone mass	7
i converting	7
diabetic conditions	7
neprilysin inhibition	7
cardiac function	7
increased susceptibility	7
right ventricular	7
orally active	7
sodium retention	7
diabetes infected	7
observational study	7
clinical severity	7
vascular aging	7
signaling events	7
bronchial epithelial	7
cellular receptor	7
ace converts	7
mental retardation	7
underlying mechanisms	7
dysregulated ras	7
receptor agonist	7
beneficial role	7
african americans	7
renin hypertension	7
cellular responses	7
cardiovascular effects	7
positive feedback	7
intracellular renin	7
ulcerative colitis	7
renal cells	7
macrophage infiltration	7
therapeutic role	7
ventrolateral medulla	7
data suggest	7
membrane proteins	7
experimental evidence	7
mouse models	7
biological effects	7
tissue growth	7
study showed	7
dependent mechanism	7
world health	7
authors declare	7
hypertensive nephrosclerosis	7
human subjects	7
also expressed	7
carotid body	7
cov spike	7
another study	7
without affecting	7
golgi membranes	7
cultured human	7
renal tissue	7
reduced risk	7
crude mortality	7
cellular entry	7
hepatic stellate	7
inhibitors angiotensin	7
vitro studies	7
advanced glycation	7
first step	7
may result	7
ii also	7
target cells	7
stem cells	7
slit diaphragm	7
two axes	7
significantly associated	7
gastric cancer	7
hxt gene	7
transmembrane protein	7
crystal structure	7
dawley rats	7
vascular disease	7
mg kg	7
lamina propria	7
increases ace	7
rodent models	7
elderly patients	7
chronic diseases	7
cells angiotensin	7
glycation end	7
terminal transmembrane	7
health organization	7
patients treated	7
active renin	7
structural proteins	7
acute myocardial	7
gene variants	7
inflammatory mediators	7
vascular endothelium	7
ace cleaves	7
significant decrease	7
sex hormones	7
inflammatory diseases	7
growth factors	7
coronavirus sars	7
disease model	7
chemoattractant protein	7
fatality rate	7
viral load	7
receptor angiotensin	7
targeting signal	7
tyrosine phosphorylation	7
inflammatory reactions	7
bradykinin receptor	7
superoxide production	7
opg rankl	6
molecular basis	6
significantly elevated	6
important roles	6
patients admitted	6
terminal dipeptide	6
antihypertensive agents	6
ii effects	6
unfolded protein	6
linker region	6
derived ros	6
epidemiological studies	6
ii signaling	6
receptor recognition	6
homologue ace	6
ace functions	6
erbb family	6
adaptive immune	6
lung inflammation	6
patients requiring	6
terminal domain	6
podocytes cultured	6
mineralocorticoid receptor	6
structural studies	6
mediated stimulation	6
may occur	6
deletion polymorphism	6
cells expressing	6
hour group	6
glycogen phosphorylase	6
ace activation	6
adjusted mortality	6
dependent kinase	6
two active	6
higher risk	6
em structure	6
expression data	6
cell killing	6
kidney injuries	6
ras family	6
peptide ang	6
arbs may	6
ace ectodomain	6
circulating ace	6
monocyte chemoattractant	6
isolated perfused	6
slgt inhibitors	6
significant reduction	6
biochemical indexes	6
including vasoconstriction	6
evidence indicates	6
might also	6
acid linkers	6
chronic hepatitis	6
mas expression	6
viral loads	6
lipoprotein receptor	6
animal experiments	6
renal damage	6
two isoforms	6
autophagosome formation	6
recent meta	6
new york	6
drug resistance	6
hour groups	6
regulatory role	6
understanding sars	6
receptors may	6
chronic liver	6
studies included	6
ros production	6
phase ii	6
infected cells	6
studies showing	6
rostral ventrolateral	6
crude rate	6
chronic inflammatory	6
gene polymorphism	6
ace genes	6
small cell	6
large number	6
epithelial cell	6
converts ang	6
prostate cancer	6
tissue renin	6
atp ap	6
also reported	6
ottawa scale	6
ventricular hypertrophy	6
cov receptor	6
type angiotensin	6
lower blood	6
retrospective case	6
water reabsorption	6
bone loss	6
hypertension angiotensin	6
ischemia reperfusion	6
patients linked	6
reperfusion injury	6
chromosome inactivation	6
process effacement	6
increased mortality	6
intracellular signaling	6
east asian	6
furin cleavage	6
ventricular dysfunction	6
renin inhibition	6
protein response	6
forming enzymes	6
induced apoptosis	6
ii blockade	6
immune complex	6
molecular weight	6
domain complexed	6
protein kinases	6
well documented	6
cell survival	6
diseases associated	6
kinase activation	6
lung cells	6
membrane versions	6
pulmonary neuroendocrine	6
intestinal ace	6
supplementary material	6
wide variety	6
severe pneumonia	6
microvascular thrombosis	6
mrna expressions	6
ill patients	6
potassium wasting	6
cell cycle	6
small molecule	6
liver injury	6
mediates regulated	6
plasma angiotensin	6
inflammatory pathways	6
ii concentration	6
cardiovascular aging	6
water retention	6
releasing peptide	6
will provide	6
terminal lipid	6
evidence supporting	6
human bronchial	6
innate immunity	6
hybrid system	6
controlled trial	6
somatic ace	6
renal diseases	6
immune function	6
lipid raft	6
higher ace	6
kinase activity	6
pulmonary diseases	6
antifibrotic effects	6
acid transporters	6
associated secretory	6
western blot	6
therapeutic approaches	6
muscle weakness	6
ras axis	6
endogenous ligand	6
lipid modifications	6
extracellular vesicles	6
transmembrane anchor	6
water absorption	6
recent years	6
distinct roles	6
platelet aggregation	6
molecular mechanism	6
protein priming	6
case reports	6
dependent endocytosis	6
podocyte depletion	6
reduced expression	6
vascular dysfunction	6
exclusively hypertensive	6
upregulate ace	6
fold higher	6
disease states	6
brain nuclei	6
i receptor	6
transcription factor	6
human tissues	6
systemic circulation	6
lumbar vertebra	6
may cause	6
active peptide	6
two different	6
high ace	6
may serve	6
higher mortality	6
new insights	6
ncov infected	6
independent mechanisms	6
acute coronary	6
angiotensinogen gene	6
case fatality	6
early stage	6
randomised trial	6
signal pathway	6
molecular biology	6
pressure response	6
damage caused	6
main effector	6
promoting effects	6
regulated ectodomain	6
original sars	6
circulating levels	6
ras might	6
lung adenocarcinoma	6
regulated aminopeptidase	6
endocytic pathway	6
tissue levels	6
adrenergic receptor	6
glomerular injury	6
induced obesity	6
poor outcomes	5
inhibitors may	5
significantly decreased	5
ii angiotensin	5
arterial pressure	5
closely related	5
increased tissue	5
vlp group	5
regulate blood	5
global pandemic	5
drug classes	5
ras drugs	5
ras within	5
linker regions	5
two distinct	5
inflammatory bowel	5
current study	5
potential target	5
circulating angiogenic	5
mesangial matrix	5
ras fusion	5
predominantly expressed	5
neuroendocrine cells	5
pathway analysis	5
therapeutic strategy	5
aii levels	5
rats treated	5
expression profiling	5
potential risk	5
aortic senescence	5
whereas ace	5
working modes	5
therapeutic strategies	5
cell damage	5
inflammatory conditions	5
novel target	5
ace inhibitory	5
glomerular endothelial	5
mediated effects	5
related diseases	5
tubular injury	5
chaperone proteins	5
commons attribution	5
coding sequence	5
may require	5
biological actions	5
inhibitory peptides	5
antithrombotic effect	5
mg day	5
ras also	5
adenine dinucleotide	5
increased covid	5
peptide metabolism	5
blood glucose	5
body weight	5
brain regions	5
aged mice	5
fat diet	5
therapeutic implications	5
heparan sulfate	5
present study	5
severe course	5
ace null	5
systolic blood	5
acetate levels	5
controlled trials	5
aldosterone secretion	5
plant food	5
five studies	5
angiotensinogen mrna	5
ii may	5
soluble form	5
quality assessment	5
digestive system	5
many patients	5
survival benefit	5
small studies	5
clinical practice	5
carboxypeptidase ace	5
systemic ang	5
higher plasma	5
interaction inhibitors	5
enzymatic activity	5
metabolism disorder	5
ace replacement	5
analysis based	5
mediated senescence	5
ii pneumocytes	5
target organ	5
organ dysfunction	5
chronic inflammation	5
facilitates viral	5
biological functions	5
inflammatory lung	5
end products	5
systolic dysfunction	5
factor beta	5
emerging evidence	5
ras function	5
important factor	5
associated coronavirus	5
arterial stiffness	5
new class	5
subsequent studies	5
sexual dimorphism	5
fda approved	5
growth arrest	5
higher rates	5
may reduce	5
ventricular remodeling	5
vlp groups	5
differential expression	5
cellular growth	5
ko mice	5
expression may	5
sd proteins	5
renal sodium	5
negatively regulates	5
inflammatory drugs	5
studies showed	5
immunofluorescence staining	5
renin release	5
substrate specificity	5
cirrhotic patients	5
captopril treatment	5
senescence appears	5
vascular system	5
pressure overload	5
confirmed covid	5
mesenchymal cells	5
human angiotensinconverting	5
studies reported	5
smad signal	5
chymase inhibitors	5
risk group	5
receptor pathway	5
diseases including	5
myocardial ischemia	5
patients receiving	5
rate among	5
arb use	5
ventilated patients	5
may account	5
rna virus	5
focus forming	5
retrospective study	5
angiogenic cells	5
cancer cell	5
factors associated	5
skeletal ras	5
hypertensive mice	5
whether ras	5
literature review	5
protease inhibitor	5
kinase inhibitors	5
plasma ang	5
podocyte foot	5
particular interest	5
bone area	5
probe sets	5
tissue factor	5
lung compliance	5
pathological cardiac	5
angii infusion	5
urinary protein	5
urinary potassium	5
respiratory disease	5
glomerular hypertrophy	5
brain barrier	5
host receptor	5
primers vk	5
clinical evidence	5
nonproteolytic activation	5
elevated blood	5
local production	5
disease angiotensin	5
mice exhibit	5
chronic administration	5
infected pneumonia	5
pancreatic cancer	5
high concentration	5
akt pathway	5
study indicated	5
atrial fibrillation	5
insulin secretion	5
mice expressing	5
differential effects	5
rat intestine	5
direct effect	5
recently demonstrated	5
hospitalised patients	5
myocardial dysfunction	5
possible mechanisms	5
cardiovascular implications	5
ras gene	5
nucleus tractus	5
two patients	5
dna damage	5
human disease	5
results suggest	5
lupus nephritis	5
whereas ang	5
term sequelae	5
dd genotype	5
life span	5
even though	5
ras involvement	5
among covid	5
downregulate ace	5
new target	5
analysis reported	5
oral mucosa	5
blockade inhibits	5
ace knockout	5
also shown	5
cause transformation	5
randomised controlled	5
alpha convertase	5
preserved ejection	5
induced colitis	5
literature search	5
forming enzyme	5
also inhibit	5
drug development	5
kinase pathway	5
hypertension hospitalized	5
low levels	5
catalytically active	5
public health	5
immune genes	5
gut microbiome	5
fibrotic effects	5
primary target	5
less likely	5
yeast cells	5
although ace	5
chronic heart	5
physiological conditions	5
human studies	5
peroxisome proliferator	5
upper respiratory	5
fatal outcomes	5
recently reported	5
nicotinamide adenine	5
activator inhibitor	5
secondary antibody	5
extracellular domain	5
filtration membrane	5
study association	5
different populations	5
adhesion molecules	5
neurotransmitter release	5
adhesion molecule	5
senescent cell	5
encodes aminopeptidase	5
protein synthesis	5
monoclonal antibody	5
septic shock	5
therapeutic effects	5
current pandemic	5
serum ang	5
rat hearts	5
stellate cells	5
renal dysfunction	5
glomerular hypertension	5
early phase	5
estrogen receptor	5
study reported	5
putative receptor	5
tissue inflammation	5
cardiac involvement	5
model predicts	5
gene transfer	5
ace i	5
underlying mechanism	5
drugs targeting	5
pathological hypertrophy	5
fanconi syndrome	5
portal hypertensive	5
increase ace	5
blood volume	5
transmembrane protease	5
widely used	5
bone resorption	5
ii level	5
endothelial nitric	5
experimental studies	5
paraventricular nucleus	5
urine potassium	5
bile duct	5
also called	5
cardiac failure	5
vascular injury	5
recombinant angiotensin	5
membrane bound	5
generate ang	5
also causes	5
dinucleotide phosphate	5
therapeutic intervention	5
ace overexpression	5
open access	5
evidence supports	5
national health	5
ace pathways	5
also showed	5
times higher	4
expiratory pressure	4
ace structure	4
novel angiotensinconverting	4
indirectly via	4
system may	4
study design	4
prone posturing	4
minimal change	4
dj donoghue	4
see note	4
compensatory mechanisms	4
tractus solitarius	4
gene transcripts	4
cardiac disease	4
proven protease	4
inhibits development	4
dm rats	4
signaling via	4
recent evidence	4
convoluted tubule	4
local pulmonary	4
periodic acid	4
arbs reduce	4
hematopoietic stem	4
hubei province	4
cd ap	4
study demonstrated	4
diminazene aceturate	4
coronary syndrome	4
competing interests	4
genetic analysis	4
hour vs	4
therapeutic agents	4
inhibitor therapy	4
endothelial ace	4
clinical presentation	4
cd cells	4
respiratory system	4
aortic stiffness	4
specific antibody	4
antihypertensive effect	4
reduced myocardial	4
ras anchored	4
rat angiotensin	4
polymerase chain	4
mediated cytotoxicity	4
nucleotide polymorphisms	4
within several	4
disease susceptibility	4
central ang	4
domain receptor	4
renal impairment	4
vascular resistance	4
growing evidence	4
differentially expressed	4
many organs	4
biased expression	4
infection may	4
sympathetic neurons	4
prospective cohort	4
related disease	4
reported mortality	4
cancer therapeutics	4
chain reaction	4
antihypertensive therapy	4
hemodynamic effects	4
sequence identity	4
transmission electron	4
tissue homeostasis	4
evidence suggesting	4
enzyme type	4
co insufflation	4
form angiotensin	4
cardiovascular dysfunction	4
receptor promotes	4
human angiotensinogen	4
receptor via	4
severity outcomes	4
situ hybridization	4
endopeptidase activity	4
asian populations	4
vascular complications	4
actions via	4
matrix expansion	4
precursor protein	4
proinflammatory cytokine	4
cellular signaling	4
intracerebroventricular infusion	4
system renin	4
axis ace	4
risk individuals	4
protein interaction	4
protease serine	4
angii antagonists	4
may act	4
deleterious actions	4
renin secretion	4
mice models	4
potential influence	4
blocking drugs	4
rat intestinal	4
proteolytic activation	4
also involved	4
acid transport	4
negatively charged	4
biliary fibrosis	4
golgi compartment	4
also responsible	4
transmembrane glycoprotein	4
increased intracellular	4
ace downregulation	4
distal sodium	4
premature aging	4
like particles	4
terminal amino	4
either ace	4
kidney diseases	4
normal tissue	4
soluble angiotensin	4
lower respiratory	4
cardiovascular patients	4
blood cancer	4
glomerular slit	4
cov family	4
dna fragment	4
activated receptor	4
cov also	4
treatment may	4
adam activity	4
cov entry	4
feedback activation	4
regulatory mechanism	4
bladder cancer	4
ras medications	4
induced inflammation	4
entry depends	4
odds ratio	4
lower crude	4
charge barrier	4
ace activators	4
human airway	4
mediated endocytosis	4
ten studies	4
regulated glycogen	4
ii produced	4
vascular damage	4
lung adenocarcinomas	4
increased oxidative	4
diabetic cardiovascular	4
conjugated goat	4
golgi targeting	4
american hypertensives	4
genetic variants	4
therapeutic effect	4
bowel disease	4
ace ko	4
potential therapy	4
bat origin	4
protein coupled	4
cyclic ang	4
catalytic domain	4
may represent	4
glomerular endothelium	4
interstitial oedema	4
vascular wall	4
may explain	4
several mechanisms	4
may influence	4
antagonist candesartan	4
data analysis	4
light microscopy	4
hepatic fibrogenesis	4
coronavirus entry	4
potent anti	4
including il	4
ras upregulation	4
arterial wall	4
drug discovery	4
binding proteins	4
ii activation	4
lower levels	4
tissue ang	4
apelin receptor	4
terminal kinase	4
enhanced thrombosis	4
aberrant ras	4
antisense inhibition	4
ventricular fibrillation	4
superoxide dismutase	4
closely resembles	4
increased angiotensin	4
hypokalaemia compared	4
mesangial expansion	4
studies also	4
surface ace	4
microbiota might	4
pathways angiotensin	4
factor alpha	4
natriuretic peptides	4
double membrane	4
also stimulates	4
cada cassette	4
higher affinity	4
including heart	4
group compared	4
tmprss cleavage	4
cerebral artery	4
dependent senescence	4
targeting function	4
carboxypeptidase angiotensin	4
individual genetic	4
increased blood	4
cirrhotic liver	4
renal renin	4
widely expressed	4
kill tumor	4
full text	4
arterial aging	4
gene reprogramming	4
binding affinity	4
threonine kinases	4
cell lines	4
reduced compared	4
cytoplasmic tail	4
cytokine profile	4
careful targeting	4
mediated activation	4
components required	4
short half	4
lung fibroblasts	4
clinically proven	4
programmed cell	4
silent hypoxia	4
cohort studies	4
antihypertensive effects	4
opposing effects	4
vsmc phenotype	4
mediated via	4
mechanism underlying	4
ards therapy	4
severe cases	4
comparative study	4
pulmonary ace	4
subgroup analyses	4
still unclear	4
probable bat	4
autophagic flux	4
derived growth	4
complex mechanisms	4
handle region	4
viral pneumonia	4
protective arms	4
bamhi site	4
respiratory infections	4
catalytic activities	4
enzyme suppresses	4
deficiency disorder	4
evidence suggests	4
also promotes	4
two receptors	4
renal failure	4
large body	4
lung diseases	4
pathological features	4
healthy adults	4
human glomerular	4
induced osteoporosis	4
novel drugs	4
protease tmprss	4
heat shock	4
varying degrees	4
airway epithelial	4
internal standard	4
study examining	4
current evidence	4
enzyme inhibitory	4
cq hcq	4
multiple organ	4
positive end	4
randomized controlled	4
mortality compared	4
remains unknown	4
cardiac arrest	4
reduced ratio	4
experimental heart	4
phosphatidyl inositol	4
compensatory increase	4
tract infections	4
ace might	4
protein complex	4
glomerular mesangial	4
biological peptides	4
perfused rat	4
probiotic species	4
nucleotide exchange	4
wuhan clinical	4
forms ang	4
cardiac death	4
shear stress	4
broad spectrum	4
electrolyte disturbances	4
colorectal cancer	4
significantly lower	4
ventilatory support	4
muscle contraction	4
atrial natriuretic	4
nobel prize	4
pressor response	4
intracellular ras	4
reversible association	4
vascular cell	4
higher odds	4
angii type	4
caax motif	4
podocyte sd	4
nasal epithelium	4
myocardial remodeling	4
studies investigating	4
conformational change	4
patients showed	4
oxidase activity	4
poorly oxygenated	4
troponin i	4
distal nephron	4
cerebrospinal fluid	4
increase blood	4
also observed	4
also express	4
reduce lung	4
ras axes	4
signalling pathways	4
protein kc	4
experimental animals	4
collagen deposition	4
last years	4
activation via	4
accentuates vascular	4
liver phosphorylase	4
threatening condition	4
serum levels	4
electrolyte balance	4
cardiothoracic ras	4
human aging	4
neonatal rat	4
partial pressure	4
pneumonia outbreak	4
int cassette	4
lysis buer	4
limiting step	4
like ace	4
matrix metalloproteinase	4
pdr gene	4
coronavirus family	4
approved drugs	4
data suggested	4
like enzymes	4
previous study	4
muscularis mucosa	4
spectrum antibiotics	4
mouse podocytes	4
change disease	4
will lead	4
nk cells	4
sudden cardiac	4
presympathetic neurons	4
regulatory proteins	4
single nucleotide	4
cultured podocytes	4
murine autoimmune	4
ras elements	4
syndrome leads	4
myocardial injury	4
key mechanism	4
protein complexes	4
arterial blood	4
glucose homeostasis	4
till now	4
tissue level	4
family receptors	4
hydrolyze ang	4
ace deletion	4
dependent pathway	4
vascular cells	4
years ago	4
term use	4
site cleft	4
key modulator	4
prefusion conformation	4
clinical use	4
via mas	4
enalapril attenuates	4
intracellular signalling	4
medical literature	4
decoy peptide	4
sham group	4
liquid chromatography	4
data support	4
pressure control	4
ura gene	4
healthy aging	4
loop diuretics	4
mobility group	4
plasma concentration	4
genetic deletion	4
regulated kinases	4
mitigate covid	4
rat lung	4
clinical prognosis	4
cell chymase	4
amyloid beta	4
york city	4
premature senescence	4
rat jejunum	4
statistically non	4
care unit	4
vitro ace	4
fibrosis induced	4
platelet activation	4
rats effect	4
fibroblast growth	4
tract infection	4
vasopressin release	4
rat hepatic	4
tubular lumen	4
receptor function	4
sympathetic nerve	4
treated groups	4
dna synthesis	4
ii acting	4
cardiovascular functions	4
dna sequences	4
increased production	4
deficiency accentuates	4
vivo studies	4
group box	4
risk patients	4
outbreak associated	4
studies suggest	4
minimum distance	4
angiotensinergic signaling	4
via ace	4
diabetic angiotensin	4
related proteins	4
possible role	4
single amino	4
related protein	4
mammalian cells	4
brain tissue	4
lung axis	4
specific receptors	4
threonine kinase	4
kc hart	4
mediated ace	4
hospitalized covid	4
carotid arteries	4
mcd patients	4
examine whether	4
mitochondrial ros	4
descriptive study	4
rna sequencing	4
sympathetic activity	4
cardiovascular events	4
pathway genes	4
iconverting enzyme	4
genes encoding	4
injury response	4
causal relationship	4
respiratory symptoms	4
glycemic control	4
microvascular complications	4
harmful effects	4
histopathological evidence	4
another important	4
cultured rat	4
rat podocytes	4
increasing evidence	4
mapk pathway	4
global loss	4
ras protein	4
intestinal inflammation	4
pdr locus	4
treated rats	4
associated nephropathy	4
chronic ras	4
high mortality	4
time pcr	4
losartan treatment	4
including cell	4
data indicate	4
aortic smooth	4
oriented perspective	4
combinatorial library	4
deficiency leads	4
cardiovascular function	4
highly correlated	4
cells may	4
sd rats	4
soluble flt	4
epidemiological data	4
stem cell	4
strong association	4
two forms	4
dependent ace	4
immunodeficiency virus	4
death rate	4
via angiotensin	4
angiotensin iimediated	4
cov virus	4
small gtpase	4
reduced podocyte	4
renal fanconi	4
cholesterol accumulation	4
protein level	4
disease patients	4
chloride ion	4
ace plays	4
induced endothelial	4
neutrophil chemotaxis	4
treat resistant	4
elevated plasma	4
autonomic dysfunction	4
per se	4
two studies	4
significant role	4
podocyte density	4
genetic polymorphisms	4
inner surface	4
renal tissues	4
high expression	4
receptor mrna	4
gene delivery	4
biological function	4
new components	4
renal potassium	4
cardiovascular hypertrophy	4
functional analysis	4
many years	4
neurons within	4
human cells	4
disease compared	4
point mutation	4
pulmonary edema	4
disease conditions	4
proinflammatory signaling	4
leukocyte adhesion	4
glucose tolerance	4
cellular mechanisms	4
new drugs	4
minimally invasive	4
mitochondrial sirt	4
coupled receptors	4
review article	4
normal physiological	4
factors may	4
apoe knockout	4
usa proc	4
several gene	4
ii antagonist	4
recent reports	4
cre recombinase	4
hong kong	4
related genes	4
low level	4
blood group	4
inflammatory markers	4
mm hg	4
intercellular adhesion	4
system revisited	3
metabolic diseases	3
drugs acting	3
dysfunctional diabetic	3
pulmonary insult	3
two strains	3
histopathological data	3
human gastric	3
cov infections	3
thoracic aortic	3
valproic acid	3
significant changes	3
regulate ace	3
ic values	3
early studies	3
asian countries	3
yeast pdr	3
kidney cortex	3
perivascular fibrosis	3
play important	3
treatment protocols	3
kidney biopsy	3
factor erythroid	3
deeper understanding	3
bronchitis virus	3
reduces hypertension	3
inflammatory thrombocytosis	3
metabolic actions	3
selective inhibitors	3
transcriptional activity	3
endogenous counter	3
vasoactive peptide	3
related factor	3
promotes antithrombotic	3
epithelial brush	3
including angiotensin	3
inflammatory state	3
electronic supplementary	3
recombinant soluble	3
might act	3
renin isoform	3
peer review	3
diabetes rats	3
related coronavirus	3
several factors	3
grade inflammation	3
genetic predispositions	3
induced aaa	3
vascular tone	3
senescence induced	3
cardiovascular pathology	3
inhibiting renin	3
src family	3
antimicrobial peptides	3
vessel exposure	3
newly developed	3
dependent angiotensin	3
ras differentially	3
clinically relevant	3
soluble neprilysin	3
myenteric plexus	3
presenting cells	3
disease progresses	3
colitis model	3
inhibitor use	3
clinical specimens	3
intracellular signal	3
saudi arabia	3
inflammatory sites	3
kinase cascade	3
network analysis	3
senescence markers	3
inhibitors present	3
ras levels	3
proximal metaphysis	3
transtubular potassium	3
treating covid	3
identified throughout	3
enzyme overexpression	3
experimental biliary	3
ace polymorphisms	3
mediated cellular	3
like growth	3
ursodeoxycholic acid	3
tumour necrosis	3
system angiotensin	3
impact gut	3
alpha subunits	3
th anniversary	3
newly identified	3
reporter genes	3
correlation analysis	3
ras status	3
online version	3
excessive scfas	3
oncogenic ras	3
longitudinal muscle	3
dna fragments	3
podocytes may	3
primary antibodies	3
protein aggregation	3
heart chymase	3
room temperature	3
international union	3
long structural	3
induced reactive	3
fulminant hypertension	3
transduction mechanisms	3
might play	3
cell function	3
profound loss	3
eligibility criteria	3
obvious feedback	3
starting point	3
infarct size	3
matrix proteins	3
celecoxib derivative	3
ii caused	3
chinese national	3
additional small	3
utilizes ace	3
arb treatment	3
urinary podocyte	3
critical outcome	3
membrane lipid	3
intervention protocols	3
two major	3
also present	3
positively charged	3
beta integrin	3
renal cortex	3
may constitute	3
well described	3
three key	3
mediated damage	3
tissue samples	3
future therapeutic	3
cause hypokalaemia	3
control animals	3
high affinity	3
factor xiii	3
host membranes	3
binding properties	3
thrombosis may	3
among african	3
cascade activation	3
microvascular endothelium	3
cyclic amp	3
better prognosis	3
extrarenal tissues	3
family members	3
metabolic effects	3
since ras	3
muscularis propria	3
pulmonary tissues	3
ii transmembrane	3
pharmacological inhibition	3
might contribute	3
signaling cascades	3
hyperpermeable yeast	3
protein receptor	3
protein bound	3
human immunodeficiency	3
conflicting findings	3
whilst death	3
altered sasp	3
mesenteric microvascular	3
three main	3
pathways involving	3
edged sword	3
classical renin	3
higher incidence	3
recent discoveries	3
cell responses	3
differences may	3
mediated vasoconstriction	3
potential mechanism	3
pulmonary pathology	3
adenocarcinoma tissue	3
golgi compartments	3
mek erk	3
type receptors	3
gene fragment	3
intestinal epithelial	3
cleavage sites	3
attenuates downregulation	3
sulphonic acid	3
target organs	3
mechanisms underlying	3
ras receptors	3
increased ros	3
retrospective clinical	3
extracellular regulated	3
specific intercellular	3
gastric inflammation	3
gel electrophoresis	3
form ang	3
cirrhotic livers	3
ras must	3
apoptosis pathway	3
receptor genes	3
carcinoma cells	3
time course	3
ii binding	3
mouse brain	3
primarily mediated	3
reverse transcriptase	3
protein binding	3
potassium concentration	3
vaccinated animals	3
protein concentration	3
urine protein	3
volume depletion	3
diastolic dysfunction	3
competitively bind	3
podocyte death	3
respiratory virus	3
specific protein	3
renal physiology	3
highly differentiated	3
one hand	3
physiological relevance	3
key factor	3
reduced inflammation	3
potential application	3
promising therapeutic	3
targeting ras	3
chain fatty	3
presenting characteristics	3
disease due	3
hyaluronic acid	3
downregulating ace	3
severe coronavirus	3
olmesartan treatment	3
associated inflammatory	3
dependent activation	3
eight amino	3
reducing oxidative	3
amino peptidase	3
renal tubules	3
human organs	3
fast green	3
hypertensive covid	3
pancreatic renin	3
mm cl	3
express ace	3
prorenin levels	3
also activate	3
chronic pulmonary	3
glucose transport	3
postmenopausal women	3
randomised trials	3
related mechanisms	3
apoptosis via	3
expression increased	3
induced activation	3
vasoprotective axis	3
risk conditions	3
sex dimorphism	3
cells express	3
bone health	3
cause increased	3
associated inflammation	3
prolyl carboxypeptidase	3
two decades	3
yeast hxt	3
rac rho	3
mainly characterized	3
pathways related	3
marrow dysfunction	3
adverse remodelling	3
surgical smoke	3
intracellular angiotensin	3
virus internalization	3
podocytes via	3
biochemical pathways	3
human small	3
decreased glomerular	3
expresses renin	3
insulin signaling	3
increased activity	3
oxide bioavailability	3
phase i	3
nep activity	3
pulmonary outcome	3
increases vascular	3
human gut	3
nm diameter	3
extracellular region	3
mediated signaling	3
striking differences	3
environmental factors	3
funnel plot	3
ace activator	3
modified yeast	3
expression level	3
vascular repair	3
alzheimer disease	3
new roles	3
play upstream	3
hippocampal ltp	3
cholesterol homeostasis	3
activated via	3
viral ace	3
driving force	3
negative feedback	3
phase reaction	3
key autophagy	3
circulating volume	3
ace also	3
hepatic resistance	3
mice infused	3
comparative map	3
cytoskeletal reorganization	3
gal promoter	3
proinflammatory arm	3
intense research	3
worse covid	3
ischemic stroke	3
virus cell	3
basal cell	3
injury sars	3
available evidence	3
systemic vasculature	3
immune disorder	3
transgenic model	3
nasal epithelial	3
ii synthesis	3
pulmonary damage	3
metabolizing ang	3
sprague dawley	3
free fatty	3
blood urea	3
activation leads	3
human liver	3
lung pathology	3
stress signaling	3
transmissive receptor	3
hydrogen bonds	3
ii clinical	3
rat prorenin	3
myocardial function	3
recent advances	3
elevated ang	3
also reduced	3
medical community	3
like receptors	3
enteric involvement	3
activation promotes	3
gene maps	3
viral myocarditis	3
human ras	3
epithelial side	3
human mesangial	3
increase susceptibility	3
local ang	3
biased agonists	3
activation may	3
bone formation	3
experimental results	3
entering host	3
first place	3
tissue angiotensin	3
cardiovascular homeostasis	3
outlet spigot	3
cell receptor	3
rate limiting	3
glomus cell	3
healthy volunteers	3
related renal	3
receptor usage	3
regulate cardiovascular	3
calcium ions	3
human gastrointestinal	3
stress activities	3
coronavirus receptor	3
vascular diseases	3
ii regulates	3
ras modulator	3
notch signaling	3
gastrointestinal diseases	3
ser thr	3
association study	3
typical acute	3
systematically reviewed	3
santa cruz	3
raf proteins	3
whose expression	3
highly selective	3
also increases	3
reparative function	3
cultured neonatal	3
induced nephropathy	3
mapk signaling	3
erk signaling	3
han chinese	3
circulatory volume	3
thrombus formation	3
may promote	3
functional gut	3
stiffness syndrome	3
healthcare systems	3
experimental model	3
renal proximal	3
pulmonary function	3
increase risk	3
second messengers	3
contains supplementary	3
experimental hypertension	3
acute tubular	3
related disorders	3
cirrhotic rat	3
axis angiotensin	3
ras actions	3
vascular reparative	3
damaging effects	3
dilated cardiomyopathy	3
gut syndrome	3
normal rats	3
increase ang	3
central angiotensin	3
renin levels	3
infectious diseases	3
modulatory effects	3
drug administration	3
motility disorders	3
restore functional	3
specific angiotensin	3
gtp binding	3
drug combination	3
study group	3
mouse ren	3
cardiac pathology	3
asian females	3
organ protection	3
prorenin receptors	3
arb relative	3
neprilysin inhibitor	3
rabbit kidney	3
via preventing	3
embryonic development	3
ultrasonic devices	3
effective therapeutic	3
new angiotensin	3
cardiac sympathetic	3
ncov sars	3
ii alveolar	3
inflammatory stress	3
proinflammatory factors	3
small intestinal	3
functional angiotensin	3
autophagy related	3
death receptor	3
systematic literature	3
transformation assays	3
diseased lungs	3
induced pulmonary	3
human recombinant	3
induced ards	3
human intestine	3
infarcted rat	3
microvascular dysfunction	3
cerebral ischemia	3
electrolyte absorption	3
reducing brain	3
dependent glucose	3
worse prognosis	3
early anticoagulation	3
related muscle	3
renin inhibitory	3
associated cardiovascular	3
expression changes	3
mm tris	3
gut disorders	3
assay kit	3
many countries	3
mediated pressor	3
chronic treatment	3
ace seems	3
unadjusted meta	3
viral functional	3
injury induced	3
receptor inhibitor	3
propria mesenchymal	3
drug screening	3
i transmembrane	3
health care	3
therapeutic option	3
murine model	3
mice carrying	3
effects via	3
confounding factor	3
mediating cardiovascular	3
homeostatic regulator	3
co filter	3
viral invasion	3
renal pathological	3
cyclic gmp	3
studies indicated	3
proximal tubules	3
suppresses pathological	3
disease ace	3
also affect	3
apelin receptors	3
tace adam	3
degrading ang	3
risk alleles	3
wound healing	3
induce insulin	3
increasing ang	3
individual variation	3
fibrosis development	3
myocardial infarcted	3
terminal catalytic	3
vasodilatory effect	3
two subtypes	3
via several	3
heme oxygenase	3
increased morbidity	3
aspartyl protease	3
linear cascade	3
potent vasoconstrictor	3
lactobacillus paracasei	3
exacerbates lipid	3
covid infection	3
gut ras	3
specific brain	3
ras polymorphisms	3
alzheimer amyloid	3
genetic susceptibility	3
toxic metabolite	3
podocyte biology	3
peptide angiotensin	3
podocytes express	3
distal convoluted	3
target ras	3
might represent	3
coronary arteries	3
separate pooled	3
plasma level	3
podocyte membrane	3
i cleavage	3
randomly divided	3
recovered sars	3
systolic hypertension	3
evidence support	3
zinc metalloproteinase	3
factor expression	3
aii promotes	3
data will	3
potential effect	3
aldosterone increases	3
podocyte number	3
also confirmed	3
potentially detrimental	3
diseases angiotensin	3
alcoholic steatohepatitis	3
related multi	3
potentially lethal	3
virus endocytosis	3
reducing ang	3
adverse clinical	3
stock solution	3
catalytic efficiency	3
might favor	3
raas inhibitors	3
calcium influx	3
system gender	3
functional integrity	3
sodium reabsorption	3
serum markers	3
differential downregulation	3
cell granules	3
vascular function	3
rates among	3
pathways mediating	3
cardiac output	3
steroidal anti	3
activated prorenin	3
via tgf	3
support choices	3
complex i	3
two subdomains	3
first paragraph	3
patients also	3
cell migration	3
male mice	3
genes whose	3
inhibits growth	3
endothelium glycocalyx	3
also increase	3