This is a list of all the questions and their associated study carrel identifiers. One can learn a lot of the "aboutness" of a text simply by reading the questions.
| identifier | question |
|---|---|
| cord-007689-0vpp3xdl | Approaching the asymptote? |
| cord-306533-lvm11o4r | The ubiquitinmodifying enzyme A20 is required for termination of Toll- like receptor responses CYLD limits Lys63-and Met1-linked ubiquitin at receptor complexes to regulate innate immune signaling Deubiquitination, a new function of the severe acute respiratory syndrome coronavirus papain- like protease? |
| cord-287855-jfrg9soy | Influenza- virus- induced signaling cascades: targets for antiviral therapy? |
| cord-285339-pwy1ry4n | Studying immunity to zoonotic diseases in the natural hostdkeeping it real The encephalomyocarditis virus Encephalomyocarditis virus is potentially derived from eastern bent- wing bats living in East Asian countries Can bats serve as reservoirs for arboviruses? |
| cord-313957-hviv5zar | The papain- like protease from the severe acute respiratory syndrome coronavirus is a deubiquitinating enzyme Biomolecules 2020 Deubiquitination, a new function of the severe acute respiratory syndrome coronavirus papain- like protease? |
| cord-305737-bnzd7b25 | What is the molecular basis of IFIT1 mediated inhibition of virus replication? |
| cord-305737-bnzd7b25 | Why is this the case? |
| cord-301362-f3lp10lm | The molecular pathogenesis of Semliki Forest virus: a model virus made useful? |
| cord-311823-85wj08gr | Does the converse hold true for a virus such as HCV, which typically establishes a persistent infection characterized by mild( or slowly progressing) disease? |
| cord-311823-85wj08gr | How then can greater benefits be gained from using functional genomics to study virus- host interactions? |
| cord-303189-ktl4jw8v | The interferon response to intracellular DNA: why so many receptors? |
| cord-312892-p72zwmtb | ( TLR3) ectodomain Pattern recognition receptors and the innate immune response to viral infection Toll like receptor 3 and viral infections of nervous system Human Toll- like receptor 8 can be cool too: implications for foreign RNA sensing Structural reorganization of the Toll- like receptor 8 dimer induced by agonistic ligands Toll- like receptor 9 processing: the key event in Toll- like receptor 9 activation? |
| cord-007382-5kb16qb7 | T cells Human deoxyribonucleases STING- dependent cytosolic DNA sensing pathways CRISPR provides acquired resistance against viruses in prokaryotes A developmentally regulated activity that unwinds RNA duplexes An unwinding activity that covalently modifies its double- stranded RNA substrate Toll- like receptor 9 processing: The key event in Toll- like receptor 9 activation? |
| cord-007382-5kb16qb7 | The ribonuclease activity of SAMHD1 is required for HIV-1 restriction Trashing the genome: The role of nucleases during apoptosis Approaching the RNA ligand for RIG- I? |
| cord-254895-ym0jsir5 | Interferon alpha/ beta and interleukin 12 responses to viral infections: pathways regulating dendritic cell cytokine expression in vivo Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/ beta MyD88-dependent and-independent murine cytomegalovirus sensing for IFN- alpha release and initiation of immune responses in vivo Viral infection switches non- plasmacytoid dendritic cells into high interferon producers Innate antiviral responses by means of TLR7-mediated recognition of single- stranded RNA Does Toll- like receptor 3 play a biological role in virus infections? |
| cord-254895-ym0jsir5 | What is the molecular basis for the rapid and robust interferon production in pDCs? |
| cord-254895-ym0jsir5 | What is the role of TLR9 for antiviral immunity in vivo? |
| cord-321607-3r736dnk | The question that ultimately arises, however, is how does the cell distinguish between pathogen- induced cytoskeletal remodeling and that due to physiologic cellular processes? |
| cord-131093-osukknqr | Hanks( lexigropher) pointed this problem in his paper where he questioned'Do word meaning exist?' |
| cord-131093-osukknqr | He questioned'How is the meaning of words represented in the mind?'and discussed the problem in the aspects of'mental lexicon'and'generative lexicon'approaches to the representation of meaning[ 51]. |
| cord-283096-qm7h4qui | : how close are the family ties? |
| cord-283096-qm7h4qui | I TLR3 in antiviral immunity: key player or bystander? |
| cord-283096-qm7h4qui | The interferon regulated ubiquitin- like protein, ISG15, in tumorigenesis: friend or foe? |
| cord-323756-atnrw9ew | Approaching the asymptote? |
| cord-351520-c5fi2uoh | RIG- I- mediated innate antiviral signaling by the dihydroxyacetone kinase RNF5, a RING finger protein that regulates cell motility by targeting paxillin ubiquitination and altered localization Innate antiviral responses by means of TLR7-mediated recognition of single- stranded RNA Poxvirus protein N1L targets the I- kappaB kinase complex, inhibits signaling to NF- kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF- kappaB and IRF3 signaling by toll- like receptors Activation of IKK by TNFalpha requires site- specific ubiquitination of RIP1 and polyubiquitin binding by NEMO Does Toll- like receptor 3 play a biological role in virus infections? |
| cord-351520-c5fi2uoh | an in- Toll- erant protein kinase? |
| cord-319501-a2x1hvkk | The action points at which viral proteins function marked with a question mark(?) represent controversial and inconclusive findings in the field or molecular mechanisms not well studied. |
| cord-319501-a2x1hvkk | announcement of the coronavirus study group Middle East respiratory syndrome coronavirus: transmission, virology and therapeutic targeting to aid in outbreak control Inhibition of novel β coronavirus replication by a combination of interferon- α2b and ribavirin Distinct immune response in two MERS- CoV- infected patients: Can we go from bench to bedside? |
| cord-343963-99rd3o79 | Hepatitis C Virus induces the mitochondrial translocation of Parkin and subsequent mitophagy Autophagy and RNA virus interactomes reveal IRGM as a common target MicroRNAs and immunity: novel players in the regulation of normal immune function and inflammation How do microRNAs regulate gene expression? |
| cord-343963-99rd3o79 | NS5A nonstructural protein: a new paradigm for phosphorylation- dependent viral RNA replication? |
| cord-328252-dk54w8z9 | 3C- Like Protease Regulates Its Interferon Antagonism by Cleaving NEMO Ubiquitin in the activation and attenuation of innate antiviral immunity Deubiquitination, a new function of the severe acute respiratory syndrome coronavirus papain- like protease? |
| cord-328252-dk54w8z9 | Cell Host Microbe Quo vadis? |
| cord-328252-dk54w8z9 | to Usurp Ubiquitin and SUMO Host Pathways Human coronaviruses: what do they cause? |
| cord-346916-jj4l9ydl | : what have we learned and where are we headed? |
| cord-346916-jj4l9ydl | Toll- like receptor 3 in viral pathogenesis: friend or foe? |
| cord-312001-8p7scli8 | Re- evaluation of the immunological Big Bang Pattern recognition receptors and control of adaptive immunity Approaching the asymptote? |
| cord-312001-8p7scli8 | The interferon response to intracellular DNA: Why so many receptors? |
| cord-307598-p54p7enk | Detection of viral RNA-which structure stimulates RIG- I? |
| cord-307598-p54p7enk | RNase cleavage products- ligands for RIG- I and MDA5? |
| cord-307598-p54p7enk | how bad is it? |
| cord-299754-tgexahwd | Do TRIM proteins function as hubs connecting different signaling pathways or different systems? |
| cord-299754-tgexahwd | For example, how many TRIMs act as autophagic receptors and what are their specific targets? |
| cord-299754-tgexahwd | How is the autophagic role of TRIMs integrated with the other functions of TRIMs, including regulation of gene expression and pro- inflammatory signaling? |
| cord-299754-tgexahwd | I interferons in infectious disease Are the IKKs and IKK- related kinases TBK1 and IKK- epsilon similarly activated? |
| cord-299754-tgexahwd | What is the interplay between the E3 ligase activity of TRIMs and precision autophagy? |
| cord-350836-1enteev7 | -I signaling Reversal of the interferon- sensitive phenotype of a vaccinia virus lacking E3L by expression of the reovirus S4 gene Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA Approaching the RNA ligand for RIG- I? |
| cord-350836-1enteev7 | A novel role for viral- defective interfering particles in enhancing dendritic cell maturation Defective interfering influenza virus RNAs: time to reevaluate their clinical potential as broad- spectrum antivirals? |
| cord-350836-1enteev7 | Methanococcus jannaschii Unlocking the DEAD- box: a key to cryptococcal virulence? |
| cord-313138-y485ev30 | -I by viral RNA Tetratrico peptide repeat interactions: to TPR or not to TPR? |
| cord-313138-y485ev30 | The long view: a bright past, a brighter future? |
| cord-313138-y485ev30 | The tetratricopeptide repeat: a structural motif mediating protein- protein interactions Structure, chromosome localization, and regulation of expression of the interferon- regulated mouse Ifi54/ Ifi56 gene family RING domains: master builders of molecular scaffolds? |
| cord-001129-gi2kswai | The roles of TLRs, RLRs and NLRs in pathogen recognition Approaching the asymptote? |
| cord-001129-gi2kswai | The symbol"."represents the same codon as the reference sequence of human MDA5 protein,"? |
| cord-001129-gi2kswai | The symbol"."represents the same codon as the reference sequence of human RIG- I protein,"? |
| cord-001129-gi2kswai | The symbol"."represents the same nucleotide as the reference sequence of human MDA5 gene,"? |
| cord-001129-gi2kswai | The symbol"."represents the same nucleotide as the reference sequence of human MDA5 gene,"? |
| cord-001129-gi2kswai | The symbol"."represents the same nucleotide as the reference sequence of human RIG- I gene,"? |
| cord-001129-gi2kswai | The symbol"."represents the same nucleotide as the reference sequence of human RIG- I gene,"? |
| cord-307914-lgprrwee | ( Gowen et al., 2007)? |
| cord-307914-lgprrwee | , 2009)? |
| cord-307914-lgprrwee | -I given that RIG- I senses the 5 0 diphosphate terminus? |
| cord-307914-lgprrwee | : DNase II deficiency prevents activation of autoreactive B cells by double- stranded DNA endogenous ligands Toll- like receptor 3 in viral pathogenesis: friend or foe? |
| cord-307914-lgprrwee | C a robust activator of MDA5 while many other defined, long dsRNAs such as poly(A: U) are not( Colby and Chamberlin, 1969; Pichlmair et al., 2009)? |
| cord-307914-lgprrwee | The interferon response to intracellular DNA: why so many receptors? |