trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram	frequency
the presence of	4855
as well as	4838
hepatitis c virus	2910
severe acute respiratory	2599
acute respiratory syndrome	2552
in order to	2470
one of the	2332
in this study	2329
the use of	2276
the number of	2234
the expression of	2207
the development of	2135
respiratory syndrome coronavirus	2094
of the viral	2026
in the presence	2007
due to the	1985
the role of	1943
based on the	1866
of the virus	1819
it has been	1745
been shown to	1739
analysis of the	1686
the formation of	1588
the absence of	1583
in patients with	1548
in addition to	1536
according to the	1514
the effect of	1507
the detection of	1448
end of the	1423
of viral rna	1390
structure of the	1383
has been shown	1380
the treatment of	1376
was used to	1374
dependent rna polymerase	1348
a number of	1307
involved in the	1284
found to be	1251
to determine the	1229
in the absence	1206
in response to	1176
of the rna	1159
the production of	1148
role in the	1114
influenza a virus	1104
the case of	1051
compared to the	1047
can be used	1031
a total of	1029
a variety of	1026
the end of	1018
is required for	1011
human immunodeficiency virus	984
in the case	983
mouse hepatitis virus	955
shown to be	954
in vitro and	950
the viral genome	949
the viral rna	945
a and b	939
of the genome	936
is associated with	935
was found to	934
expression of the	924
region of the	911
on the other	904
of hepatitis c	901
part of the	895
we found that	893
of the sars	891
a role in	880
the ability of	865
the level of	863
associated with the	857
for the treatment	855
for the detection	854
members of the	854
the other hand	851
data not shown	844
the majority of	843
the effects of	838
respiratory syncytial virus	834
such as the	834
there is a	824
present in the	815
most of the	808
of this study	803
the replication of	802
has also been	801
used as a	799
the fact that	795
be used to	795
were used to	785
well as the	783
of the protein	780
to investigate the	776
the amount of	773
to be a	772
middle east respiratory	769
the activation of	766
in terms of	764
east respiratory syndrome	759
the context of	757
of severe acute	755
in the same	754
and in vivo	754
have shown that	751
the synthesis of	749
the importance of	744
in contrast to	741
the aim of	741
in the present	740
west nile virus	739
herpes simplex virus	737
the results of	735
is essential for	735
the structure of	734
of rna viruses	730
this study was	728
has been reported	725
hepatitis b virus	722
to evaluate the	722
as a result	719
in the context	719
the present study	719
the ability to	717
of the human	717
of the most	714
vitro and in	712
the mechanism of	711
and characterization of	709
some of the	709
an important role	708
showed that the	708
polymerase chain reaction	704
and respiratory syndrome	703
to that of	699
at room temperature	696
the identification of	693
the regulation of	692
the lack of	691
in the cytoplasm	690
porcine reproductive and	685
reproductive and respiratory	684
of a novel	682
type i ifn	682
sequence of the	682
in cell culture	677
responsible for the	676
in which the	676
type i interferon	674
the host cell	668
related to the	661
has not been	661
the activity of	660
characterization of the	657
cells infected with	655
crystal structure of	654
that can be	653
in infected cells	650
the cells were	650
was used as	648
there is no	647
changes in the	645
important role in	642
activation of the	642
were found to	641
respiratory syndrome virus	640
have been shown	639
detected in the	637
strand rna viruses	635
infectious bronchitis virus	635
was performed using	633
was detected in	631
of patients with	628
study was to	628
each of the	625
is involved in	624
of the two	624
as shown in	624
cd t cells	623
it is possible	621
innate immune response	620
that of the	619
activity of the	618
understanding of the	618
found in the	618
of the host	616
it is not	614
the function of	613
have been reported	609
are involved in	605
was carried out	605
in mammalian cells	604
were infected with	595
used for the	593
as compared to	590
is one of	587
appears to be	583
was used for	582
the addition of	581
for min at	581
the innate immune	581
have been identified	574
to be the	572
the present document	571
of the n	571
observed in the	570
have also been	570
at the end	569
the surface of	567
there was no	567
were treated with	566
suggest that the	561
consistent with the	559
derived from the	558
be involved in	557
immunodeficiency virus type	556
and in the	555
the plasma membrane	552
to study the	552
was shown to	551
was observed in	549
the study of	547
a result of	547
the inhibition of	546
results suggest that	546
the binding of	545
to assess the	543
for detection of	540
an increase in	539
mutations in the	538
with respect to	538
of influenza a	536
shown in fig	535
the induction of	535
the impact of	534
similar to the	531
all of the	530
of type i	530
the risk of	528
in combination with	528
open reading frame	528
used in the	528
because of the	526
role of the	524
are associated with	522
vesicular stomatitis virus	520
was determined by	520
the course of	520
of the study	519
in the viral	519
nsp and nsp	518
the pathogenesis of	517
member of the	515
the generation of	514
a series of	514
the most common	514
were able to	513
is based on	511
viral rna synthesis	511
contribute to the	510
to display the	510
to determine whether	509
of the disease	507
as previously described	507
the evolution of	507
play a role	506
was supported by	505
large number of	505
a license to	504
were detected in	503
who has granted	502
function of the	502
display the preprint	502
the control of	502
medrxiv a license	502
granted medrxiv a	502
the preprint in	502
has granted medrxiv	502
license to display	502
a combination of	501
may not be	498
depending on the	495
the n protein	492
the author funder	492
of gene expression	491
was added to	490
the possibility of	490
the copyright holder	489
added to the	487
the interaction between	484
in the treatment	482
the interaction of	481
the immune system	481
is able to	480
of the coronavirus	478
antiviral activity of	478
at the same	478
viral rna in	477
increase in the	477
regions of the	475
of the s	474
is responsible for	474
is the author	474
of the first	473
between the two	472
rna was extracted	472
in the nucleus	471
the release of	468
the active site	468
associated with a	468
the rate of	468
the basis of	466
been reported to	466
copyright holder for	464
aim of this	464
holder for this	464
the levels of	463
wide range of	461
the efficiency of	461
found that the	460
of influenza virus	460
are able to	457
for the development	452
shown in figure	452
similar to that	451
the frequency of	450
of mouse hepatitis	450
detection of sars	449
the genome of	448
a wide range	447
compared with the	447
identification of a	446
presence of the	445
feline infectious peritonitis	445
of the cell	444
the need for	443
is the most	443
hepatitis e virus	442
in the first	442
resulted in a	441
preprint in perpetuity	441
were obtained from	440
the discovery of	440
patients with covid	439
were used for	438
addition to the	436
downstream of the	436
of the same	435
suggesting that the	435
viral replication and	435
this version posted	434
the emergence of	432
virus infection in	431
formation of the	431
binding to the	431
presence of a	430
development of a	430
the existence of	429
for h at	429
gene expression in	428
the time of	428
the analysis of	427
in the human	426
the efficacy of	426
required for the	426
mouth disease virus	426
be due to	423
the united states	423
remains to be	422
can also be	421
characterization of a	420
data suggest that	420
included in the	419
supported by the	418
results indicate that	417
are shown in	416
to identify the	416
are known to	416
rna in the	415
than that of	415
is important to	413
this work was	413
been shown that	412
cells in the	412
as described previously	411
differences in the	410
high levels of	408
on the surface	408
located in the	406
to interact with	406
has been used	406
is mediated by	405
as described above	405
it is important	404
the stability of	404
cells were infected	404
the process of	404
known to be	403
viral rna replication	403
for the first	401
the severe acute	400
on the basis	399
have not been	398
insights into the	397
at the time	395
a set of	394
led to the	394
inhibition of the	394
components of the	394
amino acid sequence	394
to understand the	394
central nervous system	393
materials and methods	392
domain of the	392
food safety authority	391
a novel coronavirus	391
be used as	391
seems to be	390
the in vitro	390
european food safety	390
the european food	389
of the three	389
the genomic rna	389
a large number	388
adopted by the	386
dna and rna	386
appear to be	386
were determined by	386
need to be	386
be used for	385
upstream of the	385
leading to the	384
shown that the	384
the immune response	383
likely to be	382
when compared to	382
viral rna was	381
were carried out	381
suggests that the	380
there was a	380
in the regulation	380
replication of the	380
is consistent with	379
and it is	377
of nucleic acid	376
comparison of the	375
studies have shown	375
may be a	375
and can be	375
show that the	375
dependent on the	375
the prevalence of	375
indicate that the	374
of the target	373
which is a	373
mechanism of action	372
the same time	372
open reading frames	372
have been described	372
referred to as	371
the concentration of	371
in the cell	371
a range of	371
the endoplasmic reticulum	371
the origin of	370
our understanding of	369
could not be	368
the sensitivity of	368
revealed that the	367
in comparison to	367
is known to	365
is possible that	365
leads to the	364
in our study	364
h n influenza	364
binds to the	364
identification of the	363
was extracted from	361
been used to	361
are required for	361
for this preprint	360
we show that	359
in the host	359
the s protein	358
from patients with	358
is important for	358
the size of	357
demonstrated that the	357
is an important	357
due to its	356
but not in	356
the percentage of	355
be considered as	354
of viral replication	354
in some cases	354
of novel coronavirus	353
by means of	353
virus replication in	353
sequences of the	352
interacts with the	352
has been demonstrated	352
nature of the	351
it is also	351
have been developed	351
in the united	351
the amino acid	350
of the patients	350
patients with severe	349
is the first	348
effect on the	348
the first time	347
used in this	347
that have been	347
a member of	346
the accumulation of	346
been found to	345
of infected cells	345
in the study	344
of a new	344
small interfering rna	344
replication and transcription	344
these results suggest	343
corresponding to the	343
the possibility that	343
and function of	343
of these viruses	342
the distribution of	340
in vitro transcription	340
properties of the	339
as described in	339
have been used	339
the potential to	339
h n virus	339
the assembly of	339
results showed that	339
total rna was	338
size of the	338
the cell surface	338
wang et al	338
to increase the	337
was found in	337
were observed in	337
the onset of	336
world health organization	336
this suggests that	336
innate immune responses	336
obtained from the	336
the most important	335
was able to	335
which can be	334
thought to be	334
results in the	334
a decrease in	334
be associated with	333
has been proposed	333
the human genome	333
analysis was performed	333
in this case	332
also known as	332
chronic hepatitis c	332
surface of the	331
were used as	331
which was not	331
of a single	331
were found in	330
were transfected with	330
the sequence of	330
in the development	329
followed by a	329
to reduce the	329
this is the	328
component of the	328
is thought to	328
interact with the	328
acts as a	327
the hepatitis c	327
were subjected to	327
cd and cd	326
virus replication and	326
based on a	326
any of the	326
the diagnosis of	326
a recent study	326
suggested that the	325
the length of	325
zhang et al	325
were incubated with	324
it can be	324
for viral replication	323
has been suggested	323
was associated with	323
the loss of	322
the design of	322
due to a	321
specificity of the	321
the proportion of	321
b and c	320
play an important	319
of the c	318
aim of the	317
translation of the	317
virus in the	317
was performed by	317
in a single	316
work was supported	316
it is a	316
in the future	315
this preprint this	315
preprint this version	315
expression levels of	314
was confirmed by	314
it should be	314
immune response to	313
depends on the	313
in the early	313
at least one	313
japanese encephalitis virus	312
can lead to	311
the spread of	311
of viral proteins	311
cells transfected with	310
the crystal structure	310
effect of the	310
red blood cells	310
of the gene	309
in the s	309
of sars coronavirus	308
due to their	308
many of the	307
that it is	307
the site of	307
their ability to	307
reported to be	307
gene expression and	306
use of the	306
of the immune	306
semliki forest virus	306
well as in	305
needs to be	305
a is the	304
relative to the	304
influenza a viruses	303
stability of the	303
rna and dna	303
the application of	302
the translation of	302
a role for	302
essential for the	301
to be involved	301
s and s	301
of human immunodeficiency	301
is critical for	301
amino acid residues	301
serve as a	300
in this work	300
has been described	300
lead to the	299
interaction with the	298
some of these	297
indicating that the	297
and evolution of	297
li et al	297
with or without	297
in the rna	296
it was shown	296
is supported by	295
of the p	295
indicated that the	295
binding of the	295
c virus rna	295
was isolated from	295
closely related to	295
is made available	295
none of the	294
the nature of	294
the relationship between	294
for the presence	294
in the field	293
to those of	293
of an rna	293
it is made	293
identified in the	292
proteins involved in	292
in the last	292
of dengue virus	292
in the control	292
to have a	292
out of the	292
sensitivity and specificity	292
as part of	291
interaction between the	291
has been found	291
of ebola virus	291
similar to those	291
of the family	290
detection of the	290
regulation of the	290
and in vitro	290
different types of	290
the sars coronavirus	289
bind to the	289
of the major	289
could be used	289
is shown in	289
from the same	289
porcine epidemic diarrhea	289
have been found	289
is dependent on	288
available under a	288
made available under	288
may contribute to	288
license it is	288
international license it	288
the combination of	288
the specificity of	287
stranded rna viruses	287
the virus to	287
as a consequence	287
in recent years	286
considered to be	286
results show that	286
one or more	285
to form a	285
the mechanisms of	285
t rna polymerase	285
to the cytoplasm	285
p and p	285
structural basis for	285
c for min	285
that there is	284
the control group	284
be able to	283
this study is	283
were collected from	283
the quality of	283
of action of	282
the nucleocapsid protein	281
in case of	281
in agreement with	281
the influence of	281
were isolated from	281
of porcine reproductive	280
by peer review	280
not certified by	280
those of the	280
study of the	280
viruses in the	280
certified by peer	280
amino acid sequences	280
in the genome	280
formation of a	279
viruses such as	279
was not certified	279
is a major	279
limit of detection	278
to determine if	278
are needed to	277
is due to	277
to inhibit the	276
samples were collected	276
in this review	276
together with the	276
in the formation	276
is that the	275
total number of	275
structure and function	275
of h n	275
length of the	275
was performed on	275
as a potential	275
the purpose of	275
were analyzed by	275
chen et al	274
the authors declare	274
to the viral	273
plays an important	272
it is likely	272
of the mrna	272
the introduction of	272
under a is	272
of the hepatitis	271
i and mda	271
mediated isothermal amplification	271
is likely to	270
by using the	270
are likely to	270
in the pathogenesis	270
the viral replication	270
can be found	269
in viral replication	269
a subset of	269
strand rna synthesis	269
nucleotide sequence of	269
were performed in	269
were shown to	269
rna secondary structure	269
site of the	268
of hepatitis b	268
genes involved in	267
resulting in the	267
to examine the	267
protein in the	267
be detected in	267
tobacco mosaic virus	266
results in a	266
expression of a	265
serves as a	265
the occurrence of	265
in viral rna	265
been associated with	264
in the lung	264
as a template	264
the range of	264
is present in	264
by using a	264
caused by the	264
data indicate that	263
been carried out	263
proteins in the	263
the ratio of	263
contrast to the	263
use of a	263
and that the	263
hepatitis a virus	262
cells were transfected	262
the result of	262
was performed with	262
the antiviral activity	261
to detect the	261
belongs to the	261
in the liver	261
there are no	260
western blot analysis	260
viral rna and	259
no significant difference	259
of nucleic acids	259
vero e cells	259
infection in the	258
the degree of	258
carried out in	258
control of the	258
which has been	258
to bind to	257
epidemic diarrhea virus	257
may also be	257
and has been	257
internal ribosome entry	257
change in the	257
there were no	256
the extent of	256
in the brain	256
results of the	255
the university of	255
a key role	255
the potential of	255
resulted in the	255
performed using the	255
r n a	255
the incidence of	254
the nucleic acid	254
infected with the	254
it was found	254
are responsible for	254
cells were treated	254
the central nervous	254
in human cells	254
are essential for	254
is not known	253
cd t cell	253
an in vitro	253
viral life cycle	253
expression in the	252
can be detected	252
may lead to	252
mutation in the	252
determined by the	251
cells treated with	251
in the past	251
t cell responses	251
the availability of	251
the m protein	250
supplementary figure s	250
the virus and	250
used to determine	250
are the most	250
is characterized by	250
newcastle disease virus	250
viral load in	250
of which are	250
followed by the	250
sensitivity of the	249
structural and functional	249
with regard to	249
is capable of	249
by the viral	249
was performed in	248
or absence of	248
this is a	248
have demonstrated that	248
terminus of the	247
innate immune system	247
mediated by the	247
resulting in a	247
the influenza virus	247
belonging to the	246
described in the	246
for min and	246
we used the	246
was shown that	246
that has been	246
structures of the	245
the novel coronavirus	245
to which the	245
detection of viral	245
we investigated the	245
the spike protein	245
the involvement of	245
has been observed	245
of the total	245
a mouse model	245
in vivo and	245
presence or absence	244
the hypothesis that	244
sequences in the	244
cleavage of the	244
the virus in	244
and stored at	243
structure of a	243
been reported in	243
patients with chronic	243
and identification of	242
rna replication and	242
yet to be	242
position of the	242
acute respiratory distress	242
hek t cells	242
were performed using	242
is composed of	242
more than one	242
by western blot	241
viral and cellular	241
swine fever virus	241
lower respiratory tract	240
of the genomic	240
of infectious virus	240
respiratory distress syndrome	240
as in the	239
been detected in	239
to play a	239
isolated from the	239
of the genus	239
by flow cytometry	239
insight into the	239
viral gene expression	239
is similar to	239
thermo fisher scientific	238
are present in	238
be used in	238
and of the	238
for viral rna	237
its ability to	237
in cells infected	237
in the blood	237
the total number	237
which is the	237
terminal domain of	236
not yet been	236
antiviral activity against	236
it may be	236
a group of	236
evaluation of the	235
positive and negative	235
an rna virus	235
treatment of covid	235
rna was detected	235
patients infected with	235
context of a	235
with the same	235
evolution of the	235
is likely that	234
tumor necrosis factor	234
the form of	234
to the development	234
upper respiratory tract	233
small interfering rnas	233
the cytoplasm of	233
conflict of interest	233
used as the	233
no effect on	232
is known about	232
encoded by the	232
mechanism by which	232
parts of the	232
cells of the	232
murine hepatitis virus	232
the severity of	232
is required to	231
for treatment of	231
to the cell	231
and activation of	231
these results indicate	231
effects of the	230
with severe acute	230
could be detected	230
we were able	230
of zika virus	229
is possible to	229
were added to	229
assembly of the	229
a review of	229
majority of the	229
key role in	229
to the virus	229
a consequence of	229
sequence analysis of	228
been reported that	228
the initiation of	228
the virus is	228
act as a	228
the samples were	228
in the lungs	228
to be more	227
with the exception	227
the beginning of	227
of the other	227
rna was isolated	227
in accordance with	227
protein is a	227
half of the	227
appeared to be	227
of the membrane	226
the e protein	226
to confirm the	226
cov and mers	226
may play a	226
rna synthesis and	226
with a high	226
belong to the	226
all rights reserved	225
seem to be	225
was performed to	225
the type i	225
considered as an	225
did not show	225
transmissible gastroenteritis virus	224
and development of	224
of the innate	224
before and after	224
that the virus	224
of the nsp	224
that may be	224
and expression of	223
coronavirus nucleocapsid protein	222
was measured by	222
to improve the	222
expressed in the	222
n a l	222
were included in	222
has been identified	222
genome sequence of	221
was obtained from	221
c virus replication	221
a function of	221
of the enzyme	221
cells were incubated	221
the molecular mechanisms	221
to test the	221
determination of the	221
in relation to	221
bound to the	221
the h n	221
liu et al	220
p r o	220
p r e	220
in vero cells	220
be related to	220
it will be	220
the viral life	220
approved by the	220
that could be	220
linked to the	220
ability of the	220
and viral rna	219
led to a	219
to the same	219
to compare the	219
of the cells	219
t cells were	219
the secondary structure	219
in a mouse	218
to be determined	218
synthesis of the	218
a critical role	218
the presence or	218
with the viral	218
gene expression by	218
in the current	217
plays a role	217
been observed in	217
of these proteins	217
the respiratory tract	217
of the hiv	217
for at least	217
c virus infection	217
a l p	217
j o u	216
were used in	216
replication in the	216
interfere with the	216
l p r	216
strand rna virus	216
was found that	216
we have previously	216
morbidity and mortality	216
o o f	216
correlated with the	216
r o o	216
u r n	216
the association of	216
shown in table	216
o u r	216
the cell cycle	215
which in turn	215
and the other	215
which may be	215
for virus replication	215
at least two	215
in comparison with	215
infected cells and	215
these data suggest	215
is not a	215
were identified in	214
as determined by	214
of the influenza	214
has been carried	214
the most abundant	214
of the authors	214
viral genomic rna	214
been identified in	214
decrease in the	214
to the nucleus	214
of at least	214
simplex virus type	214
in the literature	214
the virus was	213
are required to	213
study is to	213
the abundance of	213
of the blood	213
there is an	212
of the cellular	212
but it is	212
it would be	212
processing of the	212
to be used	212
of amino acids	212
we conclude that	212
we have shown	212
close to the	212
the recognition of	211
in the form	211
the field of	211
indicates that the	211
of innate immune	211
for up to	211
be found in	211
transcription and replication	211
in situ hybridization	211
to be an	210
residues in the	210
the structure and	210
to analyze the	210
been implicated in	210
g for min	210
that in the	210
it may not	210
t cells and	210
in escherichia coli	210
in the second	210
could be a	209
the duration of	209
of virus replication	209
is necessary for	209
difference in the	209
the exception of	209
transcription of the	209
phylogenetic analysis of	209
of the samples	209
interactions with the	209
the performance of	209
into the cytoplasm	208
reduction in the	208
with and without	208
fetal bovine serum	208
were tested for	208
important for the	207
only in the	207
rna polymerase ii	207
portion of the	207
of the dna	207
infected cells were	207
levels of the	207
studies on the	207
for use in	206
are important for	206
used to detect	206
for disease control	206
in line with	206
by rna interference	206
respiratory tract infections	206
a reduction in	206
genes in the	206
not be considered	206
the effectiveness of	206
by the authors	206
at h p	205
in a dose	205
identification and characterization	205
chronic hepatitis b	205
into the host	205
the type of	205
along with the	205
of rna synthesis	205
in this context	205
we did not	205
red blood cell	205
in the number	204
sequencing of the	204
during the first	204
we observed that	204
carried out by	204
the appearance of	204
we observed a	204
protein of sars	203
interferon regulatory factor	203
response to the	203
studies of the	203
is caused by	203
a mixture of	203
well as a	203
the potential for	203
avian infectious bronchitis	203
of the m	203
c and d	203
virus rna replication	203
of the e	203
as a control	203
in both the	203
as a model	202
of viral infection	202
of in vitro	202
with that of	202
the nucleus and	202
not required for	202
in cultured cells	202
a crucial role	201
dependent rna polymerases	201
rna extracted from	201
brome mosaic virus	201
there are several	201
is not clear	201
the genomes of	201
kim et al	200
differentially expressed genes	200
carried out using	200
we hypothesized that	200
in the virus	200
secondary structure of	200
be noted that	200
as regards the	200
of herpes simplex	200
interactions between the	200
the transcription of	200
were associated with	200
better understanding of	199
is crucial for	199
in the replication	199
reached in the	199
interaction of the	198
rna viruses and	198
is necessary to	198
an moi of	198
by the presence	198
little is known	198
higher than that	198
of the hcv	198
used to identify	197
c virus ns	197
and incubated for	197
the study was	197
exclusively by the	197
are thought to	197
the infected cells	197
were positive for	197
the recruitment of	197
of a viral	197
cells were washed	196
only a few	196
leads to a	196
of the a	196
and position as	196
in complex with	196
pcr products were	196
respect to the	196
the current study	196
its role in	196
viral replication in	196
protein of the	196
and the conclusions	196
of a contract	195
supplementary table s	195
significant difference in	195
innate and adaptive	195
to note that	195
side of the	195
is used to	195
ends of the	195
the observation that	195
be responsible for	195
h n and	194
complying with the	194
this task has	194
as an output	194
between the european	194
differences between the	194
significantly higher in	194
the issues addressed	194
addressed and the	194
as a novel	194
conclusions reached in	194
by in vitro	194
issues addressed and	194
the conclusions reached	194
many of these	194
low levels of	194
view and position	194
safety authority reserves	194
position as regards	194
authority reserves its	194
reserves its rights	194
been suggested that	194
by the authority	194
regards the issues	194
is published complying	193
document is published	193
authority is subject	193
in clinical trials	193
which the authority	193
the management of	193
transparency principle to	193
carried out exclusively	193
the authority is	193
disruption of the	193
out exclusively by	193
a contract between	193
the transparency principle	193
virus replication by	193
based on these	193
authority and the	193
prior to the	193
molecular biology of	193
safety authority and	193
with the transparency	193
been identified as	193
published complying with	193
basis for the	193
awarded following a	193
an output adopted	193
contract between the	193
a tender procedure	193
output adopted by	193
following a tender	193
principle to which	193
present document is	193
that do not	193
would like to	193
task has been	193
also been reported	192
based on their	192
cells were fixed	192
to the host	192
of a virus	192
has been produced	192
levels in the	192
the probability of	192
proteins of the	192
has recently been	192
this study we	192
to elucidate the	191
of amino acid	191
of the replication	191
of the molecular	191
located at the	191
did not affect	191
of the assay	191
were measured by	191
was assessed by	190
have been proposed	190
production of infectious	190
pcr was performed	190
the action of	190
of the full	190
virus infection and	190
depend on the	190
in vitro transcribed	189
spread of the	189
a systematic review	189
we aimed to	189
the expression levels	188
difference between the	188
of the orf	188
the limit of	188
nucleic acid amplification	188
of the sequence	188
are capable of	188
an overview of	188
on the cell	187
complementary to the	187
the functions of	187
untranslated region of	187
at an moi	187
were incubated at	187
and treatment of	187
congo hemorrhagic fever	187
for patients with	187
of the rdrp	187
of west nile	187
was used in	187
rights of the	187
to the presence	186
and analysis of	186
been produced and	186
the rights of	186
the sequences of	186
extracted from the	186
in association with	186
blood mononuclear cells	186
the in vivo	186
the kinetics of	186
one of these	186
other rna viruses	186
of the novel	186
document has been	185
without prejudice to	185
ribosome entry site	185
as it is	185
prejudice to the	185
peripheral blood mononuclear	185
high degree of	185
in the following	185
roles in the	185
immune response in	185
shows that the	185
to the rights	185
identified above as	185
infected with sars	184
produced and adopted	184
by the bodies	184
disease control and	184
type i and	184
bodies identified above	184
and adopted by	184
induced by the	184
of viruses in	184
of the proteins	184
be explained by	184
the bodies identified	184
heat shock protein	184
at least in	184
coronavirus infectious bronchitis	184
present document has	184
of the viruses	183
the selection of	183
we showed that	183
for the study	183
the results showed	183
orf a and	183
than in the	183
protein and the	183
the structural proteins	183
in the n	183
reactive oxygen species	183
we used a	183
in the sars	183
contributes to the	183
development of the	183
novel coronavirus in	183
should be noted	182
as a function	182
of the sirna	182
localization of the	182
knowledge of the	182
the establishment of	182
each of these	182
at the level	182
the first step	182
control and prevention	181
of the infected	181
is regulated by	181
to the formation	181
of the nucleocapsid	181
will be discussed	181
hcv rna replication	181
been found in	181
wide variety of	181
of the four	181
balb c mice	181
small number of	181
an inhibitor of	181
of the different	181
in vitro translation	181
was applied to	181
in rna viruses	181
blood samples were	181
critical role in	180
viruses have been	180
correlation between the	180
in spite of	180
effects on the	180
in humans and	180
from a single	180
to characterize the	180
molecular mechanisms of	180
risk factors for	180
rapid detection of	180
the position of	179
venezuelan equine encephalitis	179
mhc class i	179
of the manuscript	179
and safety of	179
the dynamics of	179
of rnase l	179
is a key	179
caused by a	178
of rna virus	178
it is the	178
sites in the	178
has led to	178
also been shown	178
of the main	178
translation initiation factor	178
was reported to	178
of more than	178
is a common	178
of these genes	178
by interacting with	178
in the infected	178
associated with an	178
and incubated at	178
may be due	178
to be associated	178
the cause of	178
with a single	177
that they are	177
evidence for the	177
identified as a	177
the outcome of	177
is related to	177
the rna polymerase	177
wu et al	177
to estimate the	177
proteins that are	177
and the authors	177
in a cell	177
the wild type	177
are found in	177
was significantly higher	177
the world health	177
analysis of a	176
and h n	176
viral and host	176
were detected by	176
in the central	176
at h post	176
the determination of	176
the progression of	176
we report the	176
unfolded protein response	176
comparative analysis of	176
were incubated for	176
in the process	176
all of these	176
hemorrhagic fever virus	176
is also a	176
be important for	175
rna virus replication	175
of the polymerase	175
cov and sars	175
information about the	175
required for efficient	175
of the virion	175
it does not	175
yellow fever virus	175
immune responses to	175
and the viral	175
this article is	175
case of the	174
high level of	174
in the production	174
to this end	174
equine encephalitis virus	174
active site of	174
mouse model of	174
the degradation of	174
binding domain of	174
of the ifn	174
to each other	174
for the diagnosis	174
the most frequent	173
lead to a	173
the rest of	173
we have developed	173
cells and the	173
when compared with	173
rift valley fever	173
is the only	173
in the c	173
a wide variety	173
rna secondary structures	173
the cell membrane	173
of the infection	173
type i ifns	173
a highly conserved	173
to generate a	173
broad range of	172
reported that the	172
nm in diameter	172
most of these	172
we sought to	172
borna disease virus	172
consists of a	172
its interaction with	172
with chronic hepatitis	172
release of the	172
distribution of the	172
final concentration of	171
clinical characteristics of	171
was performed as	171
the host immune	171
is believed to	171
which could be	171
in a study	171
of infectious diseases	171
information on the	171
influenza virus infection	171
in the range	171
ranging from to	171
for in vitro	171
bovine viral diarrhea	171
for the production	171
were significantly higher	171
t cells in	170
crucial role in	170
antiviral effect of	170
activity in the	170
dna or rna	170
in figure a	170
which have been	170
in this paper	170
authors in the	170
there are two	170
the host cells	170
the authors in	170
of blood components	169
early stages of	169
are used to	169
nucleic acid extraction	169
the viral envelope	169
activated protein kinase	169
in most cases	169
and may be	169
to form the	169
seen in the	169
the capsid protein	169
during the course	169
remain to be	169
proteins have been	169
recent studies have	169
does not require	169
tlr and tlr	169
a panel of	169
an essential role	169
a template for	168
sense rna viruses	168
findings suggest that	168
been proposed to	168
of vesicular stomatitis	168
using the same	168
are consistent with	168
efficacy and safety	168
in the expression	168
a lack of	168
we examined the	168
in this region	168
for each of	168
the significance of	168
it is known	167
likely due to	167
above as authors	167
the viral load	167
incubated for h	167
the causative agent	167
new insights into	167
the increase in	167
provided by the	167
significantly higher than	167
been demonstrated to	167
and replication of	167
on the same	167
results indicated that	167
immune responses in	167
by binding to	167
deletion of the	166
in all cases	166
because of their	166
to our knowledge	166
virus and the	166
impact on the	166
features of the	166
is a potent	166
significant differences in	166
was also observed	166
the supernatant was	166
we demonstrated that	166
lee et al	166
more likely to	166
the antiviral effect	166
were present in	166
for this purpose	166
previous studies have	165
that they have	165
evidence for a	165
years of age	165
was detected by	165
analysis revealed that	165
crystal structures of	165
the isolation of	165
leading to a	165
the ns a	165
the viral polymerase	165
of these two	165
as a negative	165
vivo and in	164
functions of the	164
and have been	164
the cleavage of	164
in clinical samples	164
of all the	164
in the region	164
associated with severe	164
relationship between the	164
to provide a	164
result in the	164
were collected and	164
part of a	164
cells were then	164
by a single	164
to the target	164
study showed that	164
was not detected	163
classical swine fever	163
mice infected with	163
a major role	163
the location of	163
used as an	163
in the two	163
in the mouse	163
were grown in	163
kindly provided by	163
has to be	163
is not required	163
t cell activation	163
further studies are	163
of middle east	163
under the control	163
of protein synthesis	163
avian influenza virus	163
isolated from a	163
are based on	162
multiplicity of infection	162
a negative control	162
no significant differences	162
of the antiviral	162
to enhance the	162
to viral infection	162
influenza a and	162
is needed to	162
functional analysis of	162
been described in	162
two types of	162
and for the	161
higher than the	161
required for viral	161
a h n	161
demonstrate that the	161
stages of the	161
i and ii	161
functions as a	161
mesenchymal stem cells	161
diseases such as	161
is not yet	161
of the capsid	161
should be considered	161
derived from a	161
there are many	161
we propose that	161
important roles in	161
in animal models	161
room temperature for	161
in ml of	161
the difference in	161
characteristics of the	160
this type of	160
the phosphorylation of	160
has shown that	160
the roles of	160
shown in the	160
a patient with	160
basis of the	160
supported by a	160
this may be	160
the orf a	160
result in a	160
h n viruses	159
the results were	159
of the pandemic	159
of coronavirus disease	159
rna interference in	159
was evaluated by	159
result of the	159
could also be	159
is an essential	159
in the course	159
transmission electron microscopy	159
are listed in	159
in tissue culture	159
and cd t	159
with the host	159
terminal region of	159
a and c	159
inhibition of viral	158
known about the	158
that there are	158
for the synthesis	158
the need to	158
is a novel	158
lower than that	158
mechanism of the	158
used to generate	158
limited number of	158
the contribution of	158
of hepatitis e	158
inhibitory effect of	158
aspects of the	158
have been detected	158
up to days	158
contributed to the	158
and did not	157
infection of the	157
results demonstrate that	157
proved to be	157
agreement with the	157
we demonstrate that	157
of ns a	157
this study were	157
next generation sequencing	157
is expected to	157
viral nucleic acid	157
with severe covid	157
attributed to the	157
a broad range	157
immune response and	157
transfected with the	157
viral nucleic acids	157
to control the	157
two of the	156
in a variety	156
for the virus	156
our results suggest	156
may be the	156
focused on the	156
of a protein	156
was identified as	156
nucleocapsid protein of	156
that are not	156
there have been	156
isolation and characterization	156
it was also	156
fact that the	156
a concentration of	156
mediated mrna decay	156
the delivery of	156
mapped to the	156
by the addition	156
and orf b	155
of sindbis virus	155
more than of	155
of the mhv	155
taxonomy of viruses	155
of the h	155
but not the	155
allowed us to	155
of blood donors	155
from infected cells	155
form of the	155
for hepatitis c	155
significant increase in	155
fold increase in	155
of total rna	155
the molecular biology	155
international committee on	154
coronavirus associated with	154
proteins such as	154
the age of	154
we analyzed the	154
it has also	154
a period of	154
yang et al	154
is the major	154
at least three	154
data show that	154
to develop a	154
in the clinical	154
a comparison of	154
the influenza a	154
the case for	154
viral diarrhea virus	154
not appear to	153
the middle east	153
focus on the	153
as compared with	153
in the serum	153
as an alternative	153
predicted to be	153
evidence suggests that	153
in this way	153
to generate the	153
ns and ns	153
has been developed	153
of murine coronavirus	153
rna and the	153
of the present	153
and specificity of	153
note that the	153
the interaction with	153
rna viruses are	153
coronavirus nonstructural protein	152
a family of	152
of our study	152
increased expression of	152
major role in	152
of a large	152
type i interferons	152
was analyzed by	152
possible that the	152
degradation of the	152
were purchased from	152
in hong kong	152
to define the	152
institutes of health	152
development of new	152
was present in	152
the understanding of	152
modification of the	152
at the n	151
replication and pathogenesis	151
have to be	151
during viral infection	151
implicated in the	151
we compared the	151
of host cell	151
implications for the	151
were cultured in	151
efficiency of the	151
coronavirus spike protein	151
was no significant	151
is expressed in	151
analysis showed that	151
of the genes	151
or in the	151
mechanisms of action	150
and the number	150
importance of the	150
of the world	150
was determined using	150
expression level of	150
the results obtained	150
the growth of	150
studies showed that	150
have been observed	150
on the viral	150
the safety of	150
we hypothesize that	150
causative agent of	150
our results show	150
pattern recognition receptors	150
cellular and viral	150
the two groups	150
agarose gel electrophoresis	150
in a similar	150
authors declare no	149
of the population	149
had no effect	149
national institutes of	149
and the rna	149
in this regard	149
to produce a	149
mechanisms by which	149
of the murine	149
studies are needed	149
may serve as	149
genomic rna and	149
zhou et al	149
rna from the	149
to interfere with	149
rest of the	148
the capacity of	148
acute lung injury	148
the region of	148
ns a and	148
for each sample	148
cells were seeded	148
to the rna	148
plasmacytoid dendritic cells	148
genome of the	148
has the potential	148
the transmission of	148
the last years	148
reported in the	148
molecular characterization of	148
view of the	148
to better understand	148
inhibitors of the	148
and rna viruses	148
by centrifugation at	148
was identified in	148
mutational analysis of	147
of influenza viruses	147
absence of the	147
of the ns	147
of the entire	147
in conjunction with	147
to explore the	147
are summarized in	147
virus nonstructural protein	147
a and a	147
model for the	147
of feline infectious	147
of up to	147
huang et al	147
multiple sequence alignment	147
and amino acid	147
both in vitro	147
course of the	146
were identified as	146
evidence that the	146
the basis for	146
sequence in the	146
compared to control	146
of this virus	146
we have also	146
believed to be	146
hospitalized patients with	146
was to investigate	146
of viral infections	146
context of the	146
it appears that	146
is difficult to	146
to prevent the	146
organization of the	146
to obtain a	146
host immune response	146
rna synthesis in	146
a significant increase	146
in both groups	145
the reduction of	145
the international committee	145
of the small	145
compared to those	145
committee on taxonomy	145
protein has been	145
purpose of this	145
is a highly	145
in of the	145
the preparation of	145
occurs in the	145
production of the	145
is the case	145
molecular basis of	145
to ensure that	145
do not have	145
used to treat	145
and subjected to	145
the characterization of	145
composition of the	145
no conflict of	145
inserted into the	144
the n gene	144
human coronavirus e	144
role in viral	144
and found that	144
we performed a	144
cells were harvested	144
is found in	144
results were obtained	144
of the structure	144
in the cytosol	144
has not yet	144
by the host	144
the leader sequence	144
real time pcr	144
participate in the	144
have the potential	144
performed as described	144
a better understanding	143
on taxonomy of	143
rna dependent rna	143
be applied to	143
rna synthesis by	143
an average of	143
early stage of	143
sequence of a	143
of the type	143
sars and mers	143
was the first	143
rna viruses in	143
life cycle of	143
site in the	143
cloned into the	143
centers for disease	143
of the spike	143
in the cns	143
in virus replication	143
a final concentration	143
of the replicase	143
of the interferon	142
were identified by	142
were stained with	142
defined as the	142
transcription and translation	142
replication in vitro	142
a viral rna	142
phase of the	142
reduction of the	142
was based on	142
be useful for	142
a new coronavirus	142
for the identification	142
of the leader	142
valley fever virus	142
linked immunosorbent assay	142
cell lysates were	142
patients in the	142
may be involved	142
be attributed to	141
mosaic virus rna	141
analysis of rna	141
been reported for	141
viral rna polymerase	141
to measure the	141
rna polymerase and	141
the gene expression	141
that had been	141
of cd t	141
at the beginning	141
the cytoplasm and	141
the accuracy of	140
can result in	140
to be highly	140
in this process	140
essential role in	140
they can be	140
other members of	140
novel coronavirus from	140
for more than	140
a significant reduction	140
to be important	140
and quantification of	140
of the interaction	140
we developed a	140
not affect the	140
and pathogenesis of	140
of the reaction	140
the method of	139
entry into the	139
orders of magnitude	139
and it was	139
a study of	139
rna viruses that	139
viruses and their	139
in the cells	139
the integrity of	139
in vitro studies	139
is known that	139
and release of	139
to contribute to	139
the construction of	139
to act as	139
figure s a	139
the entry of	139
is used for	139
recent advances in	139
account for the	139
around the world	138
transferred to a	138
regardless of the	138
in hepatitis c	138
of extracellular vesicles	138
their role in	138
assays were performed	138
and inhibition of	138
was to determine	138
the goal of	138
of n protein	138
a model for	138
the human immunodeficiency	138
by the virus	138
for production of	138
similar results were	138
of rna and	138
there has been	138
experiments were performed	138
authors declare that	138
state of the	138
infectious peritonitis virus	138
adaptive immune responses	138
not associated with	137
to the human	137
and is a	137
new england biolabs	137
involved in viral	137
origin of the	137
explained by the	137
review of the	137
in close proximity	137
stranded rna virus	137
cells were grown	137
amino acids in	137
of blood products	137
found to have	137
the ebola virus	137
in the nucleolus	137
with the use	136
copies of the	136
absence of a	136
studies have demonstrated	136
mode of action	136
of the complex	136
influenza c virus	136
determine whether the	136
several studies have	136
for minutes at	136
level of the	136
presence of viral	136
inhibition of hiv	136
in the family	136
is essential to	136
of the t	136
the properties of	136
in a recent	136
we evaluated the	136
of innate immunity	136
molecular weight of	136
in another study	136
for this reason	136
the group of	136
all of which	136
ns a protein	136
incorporated into the	135
to facilitate the	135
shown to have	135
able to detect	135
except for the	135
elements in the	135
investigation of the	135
give rise to	135
were generated by	135
of a specific	135
quality of the	135
a component of	135
was the most	135
to the control	135
we believe that	135
a previous study	135
vp and vp	135
significant reduction in	135
pandemic h n	135
green fluorescent protein	135
vero cells were	135
in the sample	135
compared to controls	135
in the middle	135
of the corresponding	135
and the results	135
is in the	134
patients treated with	134
cells in vitro	134
for the viral	134
included in this	134
which results in	134
host gene expression	134
infected with a	134
affected by the	134
applied to the	134
the leader rna	134
the differences in	134
an outbreak of	134
initiation of translation	134
model of the	134
transmission of sars	134
amplification of the	134
like to thank	134
of this protein	134
beginning of the	134
the idea that	134
as measured by	134
eukaryotic initiation factor	134
a part of	133
steps of the	133
the mechanism by	133
of the current	133
of genomic rna	133
specific for the	133
collected from the	133
which leads to	133
of the structural	133
presence of sars	132
even in the	132
were analysed by	132
to the n	132
associated with increased	132
was designed to	132
it is well	132
of both the	132
considered as a	132
large numbers of	132
rna chaperone activity	132
an increase of	132
step in the	132
the concept of	132
the life cycle	132
in peripheral blood	132
equine arteritis virus	132
avian influenza a	132
not detected in	131
been used in	131
studies have been	131
national institute of	131
allowed without permission	131
reuse allowed without	131
figure a and	131
to create a	131
h n pdm	131
listed in table	131
no reuse allowed	131
in the plasma	131
n influenza virus	131
to predict the	131
of rna recombination	131
the results are	131
because of its	131
of viruses and	131
inhibitory effect on	131
replicate in the	131
cells were cultured	131
presence of an	131
nanoparticle tracking analysis	131
the structures of	131
increased risk of	131
the rna was	131
murine leukemia virus	131
as described by	131
in our laboratory	131
molecular dynamics simulations	131
data on the	131
by use of	131
the prevention of	130
was incubated with	130
of the transcription	130
interacting with the	130
and at the	130
is a member	130
the highly conserved	130
weak d type	130
may be used	130
systemic lupus erythematosus	130
rna recombination in	130
was observed for	130
so that the	130
of the drug	130
of the putative	130
innate immune signaling	130
lymphocytic choriomeningitis virus	130
cells in a	130
the complexity of	130
the s and	130
that did not	130
it is necessary	130
can be achieved	130
is sufficient to	130
be required for	130
in host cells	130
an example of	130
were inoculated with	130
the diversity of	130
influenza a h	129
in t cells	129
at the c	129
produced by the	129
stress granule formation	129
levels of viral	129
the interactions between	129
these data indicate	129
for nucleic acid	129
of the large	129
coronavirus mouse hepatitis	129
blood and blood	129
the unfolded protein	129
min at room	129
in the respiratory	129
studies suggest that	129
of t cells	129
amino acid substitutions	129
in prostate cancer	129
were collected at	129
a positive control	129
is highly conserved	128
on the host	128
the vast majority	128
school of medicine	128
modulation of the	128
assessment of the	128
it is clear	128
in the other	128
the s subunit	128
is not the	128
been used for	128
up to of	128
attached to the	128
the inhibitory effect	128
version of the	128
the start of	128
the molecular basis	128
pcr assay for	128
to explain the	128
is determined by	128
as the most	128
long noncoding rnas	127
emerging infectious diseases	127
to the end	127
activity in vitro	127
of viral particles	127
of the sample	127
and as a	127
defective interfering particles	127
reverse genetics system	127
it possible to	127
in living cells	127
the golgi complex	127
may have a	127
a and orf	127
we present a	127
the dengue virus	127
to investigate whether	127
clinical features of	127
were obtained by	127
of the wild	127
with ml of	127
proven to be	127
occur in the	127
a broad spectrum	127
were divided into	126
this indicates that	126
was to evaluate	126
were maintained in	126
such as those	126
involvement of the	126
it is unclear	126
higher levels of	126
of respiratory syncytial	126
as one of	126
cell culture and	126
fusion of the	126
but also in	126
role for the	126
domains of the	126
infection in a	126
as a new	126
of which is	126
by reverse transcription	126
for in vivo	126
borne encephalitis virus	125
in hela cells	125
and does not	125
may result in	125
have developed a	125
was defined as	125